<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="https://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0X7</accession>
    <name>A0A1D2M0X7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008005">
        <property type="protein sequence ID" value="ODM86614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0X7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10845" checksum="BB1BC48A54146E5A" modified="2016-11-30" version="1" fragment="single">AEEKPVGKEEEYLEKFLPFKFQGLDELRRMKEEDRRRLLRKNATCLSLFISAKQLFGRLKDEWDDMKHDLDQAALGYMKELVVIAKEPEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M127</accession>
    <name>A0A1D2M127_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007748">
        <property type="protein sequence ID" value="ODM86669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M127"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903356" evidence="1">
        <location>
            <begin position="20"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="66" mass="6802" checksum="B29A018A9ABC4229" modified="2016-11-30" version="1">MSRLFALLVLVAVIAVANAQYYGGYYGGLGTYGVGTYGAGIGYSNIGYGYGGYSGLGLGYGAYYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2J3</accession>
    <name>A0A1D2M2J3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chitinase domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_19495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005937">
        <property type="protein sequence ID" value="ODM87187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2J3"/>
    <dbReference type="STRING" id="48709.A0A1D2M2J3"/>
    <dbReference type="OMA" id="YYKNEMG"/>
    <dbReference type="OrthoDB" id="10254444at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070492">
        <property type="term" value="F:oligosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02876">
        <property type="entry name" value="GH18_SI-CLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000002">
        <property type="entry name" value="Chitinase domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000028">
        <property type="entry name" value="Chitinase domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46066:SF2">
        <property type="entry name" value="CHITINASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46066">
        <property type="entry name" value="CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0458">Lysosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903420" description="Chitinase domain-containing protein 1" evidence="8">
        <location>
            <begin position="28"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="9">
        <location>
            <begin position="88"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM87187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="399" mass="45158" checksum="F1DE21BD0315D159" modified="2016-11-30" version="1">MWSVHLYNKAAALFFLVVVLIIPLVFGTITPSDKKSKDKDSAQTTFKKGPLTENVFERGLVTINPTPLDIIYESRAFCSKASERTVTLPVLGYVTPWNSHGYDVAKTFANKFTMISPVWLQINRKPTGEYYVTGTKDIDLGWIRDVRKRGKRSGVKIIPRVLFDGWSGEDYYKLFTSKVEIKELTKTVVAILEVYEFDGVTLELWSQLGGQARSALHTLVKAFGVGMKKAGLTFVLVIPPPLTNQGGPGMIELEDIQAVYSYVDYFSIMTYDYSRPDRPGANSPIKWIQKCIEALSVDELDREKFLIGLNFYGYQYTSTGGQPIIGHEYLTALGKAKKLEWSEDAEEHFFEVKDKGGRRTIFYPTLMSIHRRIKLAEKLGCGLAIWELGQGLDYFYDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M312</accession>
    <name>A0A1D2M312_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005494">
        <property type="protein sequence ID" value="ODM87358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M312"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="20266" checksum="839DDB2432216EF2" modified="2016-11-30" version="1">MPRPTPPPHCTLENNEICALGLSQFEEPDDPLRGGISVLKPKWVFRLTLLMENAKGIGPGSFSSLLVDVDSERIVEPIWKQRSAALFNQRIGKTGGNVLERWISMQTLPLAPGKHMSLQSSGVGHNENAFVGRRTNTSSGSDKRDAQWSLTIDPHLPKPEFASSKSITDNIASNLEHKYPRGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4R2</accession>
    <name>A0A1D2M4R2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription initiation factor IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004315">
        <property type="protein sequence ID" value="ODM87966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4R2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="76" mass="8549" checksum="506D835F536D1D0A" modified="2016-11-30" version="1">MCLVVRVSNSRPAVFYYQFHQNSQRIFGGLISLRAVIMSRVDFEQAPEAPLVEDVRAGGQLCSERGLVVSDRYAMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M569</accession>
    <name>A0A1D2M569_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004182">
        <property type="protein sequence ID" value="ODM88051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M569"/>
    <dbReference type="STRING" id="48709.A0A1D2M569"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="69"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="248" mass="29027" checksum="91819A21D18534BC" modified="2016-11-30" version="1">METLRINTSELAIFSKFEEAGLTELKQHIEGKSARKNNVEMAWDTLKLYAENRFRHYPEIFPIEAPSYIRDLVAKHVCGVLKNRDKFGRRILFFDMSKWDINDFSLDDLTIAGVIGAEAFWRNPEILENGLIIVENTIGFGMGHAKQHTMSRMNRMRNVFVQSFPVSIQGIFYLRMPYLFTLIFKMSRHLFPKKIRSRMNCYSSNQEPTELYDIASPDILPEWMGGKLKIEDAVEDAEFYERFLPHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5L8</accession>
    <name>A0A1D2M5L8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003971">
        <property type="protein sequence ID" value="ODM88204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5L8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19831" checksum="AE54FF852F18E9C2" modified="2016-11-30" version="1">MELFISGNCGVQYTYSIAYYSGMREEDMEHVIKHIWPLLVQKKFGVTVRCNKTRKLVAALLNCDHMDKTKFKQWAGISYPSKYRMEMIDQMDLVFRTKTMLAKALELARGAGFKSMYLMVFDHVSEEFVVDLFGFEVIEIMHVNQFVSSDGVIPFHLVPDYVCGTVLYKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6D2</accession>
    <name>A0A1D2M6D2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003483">
        <property type="protein sequence ID" value="ODM88516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6D2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="16454" checksum="2948058F0D6D83CC" modified="2016-11-30" version="1">MLGNGNGLCRREQCLGSFIQAFDTPYPLKAPLGDRYVHDYTKGWWKLQQKSDVNITADSFEEQFKDLTSDSVNSNKSIYRTARLGTTCEACGRKNVSMIVAIVILSVLCFGLIMPVVYLYNGNIFRRLGQRDHVKFQVLSEDVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6V8</accession>
    <name>A0A1D2M6V8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003335">
        <property type="protein sequence ID" value="ODM88661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6V8"/>
    <dbReference type="STRING" id="48709.A0A1D2M6V8"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="2"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="213" mass="23512" checksum="14A714CE2A06CC86" modified="2016-11-30" version="1">MLGGSTSTNFMMYVRGNKEDFNRWSTEDAVGDPQWNYENLLPYYKKPEDYNGIYASDPASAQYHGKGGLLNVATHDYMPGVEEFLAAAQEKGYTVGDYNGANQEVFSKVDVTTQDGWRESTYRAFYKDTGKPSNLCIKKYALVTKINFRPIAIPGKPRKAVGVTYQRQGLTRSVTATKEIILSAGAFGSAKILLLSGVGPAAHLRSLKVTEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7N3</accession>
    <name>A0A1D2M7N3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 4c3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_17713</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003016">
        <property type="protein sequence ID" value="ODM88969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7N3"/>
    <dbReference type="STRING" id="48709.A0A1D2M7N3"/>
    <dbReference type="OMA" id="INHEIME"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM88969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="534" mass="61490" checksum="D9A06C3A74C6F3FC" modified="2016-11-30" version="1">MFWALLLISGVVSYLLLIKLPKRQALLSKLASIKGPPALPLVGNAFDFQVPKRDILPLLKGYLDSYGPRLKIFLGMQPYIIIANAADTEKILSSQTQIEKSADYDRMHDWLGLGLLTSRGEKWFHRRKQLTPAFHFKILEDFLRVFNEQCLVFKGVLEGKMREKKAFDIFPVITHCALDIICETAMGRKVFVQQKSDSEYVKAIYRLSDLVQYRQFRPWLHSDLMWKLSSSGKENDQCLKILHGFTDLVIRERKEERAEMLKESPKEKNSKQDDGVYMNCTYENCIQLFDSVLDTLILNFFSIAKKKLAFLDLLLDAQQTDATLTDKNVREETDTFMFEGHDTTSAAASWTTFLLSLHPEYQTKVHQEMDDIFGSDRTREVTMADLSKMKYLECCIKEGLRIFPSVPFIGRKLTKDQTLDDGVVLPQGVTIMCLIYFLHRDPKVFPNPEKFDPSRFAQEEGGTQGRHPFAYVPFSAGPRNCIGQKFAMMEEKVMISTIFRNFRVHAAERMEDVDVLCELITRPEAGLHVTLEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8E8</accession>
    <name>A0A1D2M8E8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exoskeleton protein RP43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002813">
        <property type="protein sequence ID" value="ODM89201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8E8"/>
    <dbReference type="OrthoDB" id="8297242at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903633" evidence="2">
        <location>
            <begin position="20"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="299" mass="32055" checksum="ED700C34979D3576" modified="2016-11-30" version="1">MKVLASFCLSLVLCQVGRASVLPGQVEKQPLVDVIHYNSGLKTFSPLSSDSSLLTSCNGVLNATSGGIAYRAFEPIAENERCVWTIRGGNAGGFSLNVLNLGISNSSSNTQVIATCLRRGETLANHILLNQTGPVNGVSYCNVLVITFASGSEVSGSTGFVLEYSVLRSSSLSPRSQDYIIDAGTAGIIRHPNSASRYENYELNTFIILPTLGSNTNVIYFRGSLEADYCYDNLSVYRFNATSVAPTKWEYKGRICGHILSDFISNGDLILITFDTDQSVVGTGFQLAIAPSDAAQCQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9M3</accession>
    <name>A0A1D2M9M3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002483">
        <property type="protein sequence ID" value="ODM89641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9M3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="68"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM89641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="288" mass="33184" checksum="64772AA77B828242" modified="2016-11-30" version="1">MNDVVQHIAAIQQYISDMKAQLAQKEAVISKMKTEFTKNNEIYKDYYKKLLHAARFREAESTKSKEEAVKWKEEAAESKEKVERLEVAEQRMKEHVLMAQEEKELVIMENLALEQQVKDQLEKISTLENQNHLLMEERTETAGPARKKVKRSISQAAHGCRKRPTLEERHAEDPSKVMDGYFFCKCGSVFLSSDKLNGHINRASKRKLVHEFCDEGCSANDFISFCKHLQQKHNIMLDGKMQTGCFVCGQALTTREEFVAHYQENHNPAESELGCRPHPTELCLVSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA33</accession>
    <name>A0A1D2MA33_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L32, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_16838</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the mitochondrial large ribosomal subunit (mt-LSU). The mitochondrial ribosome (mitoribosome) is a large ribonucleoprotein complex responsible for the synthesis of proteins inside mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002324">
        <property type="protein sequence ID" value="ODM89846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA33"/>
    <dbReference type="STRING" id="48709.A0A1D2MA33"/>
    <dbReference type="OMA" id="DTCGHHY"/>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM89846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="24558" checksum="7AF2983BF810B2D5" modified="2016-11-30" version="1">MKGYLTAIALRLSATDSIRGLKKLTELLFPFPKGFPPGLAVAGAPSTLPPIPMPSATMEDKKAEGFVWGVPKRRRSIETRLTRKFGVLEWHWKLIKPKYNLLVCDTCGHHYEAKHLCRNCYEKTMEETKLIRESMEAKFGHSPMDKDVIVLYESDKQSVPTDTTPSLNASNKLIVELPKNRPTFFSPNLLQKSTAGANRKVKDVTATDPVPIVHKTPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA48</accession>
    <name>A0A1D2MA48_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002390">
        <property type="protein sequence ID" value="ODM89764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA48"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903690" description="Protein quiver" evidence="1">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12711" checksum="E5AA848917C6D1AF" modified="2016-11-30" version="1">MDQLVTSTLAILLTIIVSTEALNCYLCGHIENDLPKPNDWRRHSSCAAGNQPNSKFSTNCNDLDYFEMGSGIFIGTQKDEPKGGPPTVNLTSIMENSPVTSLALHLISRVYLELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAF5</accession>
    <name>A0A1D2MAF5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002265">
        <property type="protein sequence ID" value="ODM89975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAF5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="127" mass="14741" checksum="FF71FD8C44DFEBCC" modified="2016-11-30" version="1">MEMEVDLHLFQFPFLCYCRSRVRKLRRDSCRDRNAVIKTHPEERVLSEPVKSFLEEEPLLPKVVINSSEGGIKLTLKENENSMCDNNLVNLFSQLFEKSPVDPDKLEALKRHCVLMNSLYIALSKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBK5</accession>
    <name>A0A1D2MBK5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras-GEF domain-containing family member 1B-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16379</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002048">
        <property type="protein sequence ID" value="ODM90302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBK5"/>
    <dbReference type="STRING" id="48709.A0A1D2MBK5"/>
    <dbReference type="OMA" id="KASYECE"/>
    <dbReference type="OrthoDB" id="20825at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF356">
        <property type="entry name" value="FI05912P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="352"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="514"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="763"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="216"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="770"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="786" mass="86752" checksum="26803695596D8BD2" modified="2016-11-30" version="1">MEPLQAIDDLEIQEKVESLAGKGTRVIDCEKSTKFQTEEVLLVNGFPVPLNGEEGIRIKEALLAGHVPPCDLLNEILMRAGILKNPVELETTMNVKTTTKTTEVLTLRDKNGLLLDERLKEVEEDNEYKSTSKEVWKKDNSKCMDRLAKCVEKVNFGSSTSVATNATSCVSSNGSSSGGSSTTGLLGVGSASGGSSPYNAPSTITSIPTNYFSAKSSMTNSPTPSTSMKHSHSPQSSFSSGISEASGSVSGSSTASSRLSPSIFGTVASSPTSDFSYSANHQRKTLPQTSISANGSIPSNCSIVSNGSHSEEPHAKVANATINGSIDTVQNSTSTAAPKSGTHEWDNALVYQETNLISGTIDALIQHLVPTQSYYPDRAYVFAFLLSSRLYIRPHELLGRVFRLAMATPSHSPKYQMAKEAKIISNVVQLLGEWAELFPYDFRDERMMAHVRTITQKCVSVEPPIRNEVSQLLTSLLARLTALERYEDFLHRINTEAALGEPATAPSILTICPNPTMLSQQLTHIELERLSNIGAEEFVQAFAKETSQVETRYKDMKKTRNLESYVQWFNRLSYYVATEICKMPKKKSRVRVVEYWIEAARECFNIGNFNSLMAIIAGLNMSPVTRLKKMWAKVNTAQLSILEHQMEPSSNFSSYRSTLKQLYFLTTRHFDVISFVHCCRLGNGHINFDKFWQLAKQVTEVVAWQQITCPFPKVQTVITSLQTAPIFGESALCLASYDCEPADNAQEKERLKYLRQDETTAKGCLSTGSSKEKELDTPKSKSKSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBQ1</accession>
    <name>A0A1D2MBQ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine-protein kinase/endoribonuclease IRE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_16323</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002014">
        <property type="protein sequence ID" value="ODM90359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBQ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MBQ1"/>
    <dbReference type="OrthoDB" id="8187887at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="69"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM90359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="340" mass="39079" checksum="0EC083B1218A10F0" modified="2016-11-30" version="1">MEIDGSNSEDEDTFSPTRQETDKKLFGKTFGTDNKKKTNVLKRPRKPRANIRRPNTVKMTRLHGTDIAYTDDIKIGQGATSIVYKGYYGEIPCAVKRVDSEYVDVYENELAIWQHMKDKTEDGNVNIVSLFKWHPWKEGGGGTTYYFAMELALCDLAKRVKELKQWRDAKDPQFVEQEKKLPRFLHGAVKGLMWIHNKRILHRDIKPENVLIFETSNGEIAKLGDFGISRKLSETSTGTNSVGRGTSDWMAPEALQAMNNEETFFSTRNIDIFSLGMTSHYAISLGSHPFKFKSRFGIFIMTNIMQKSVQPTNLNYPHLDADHLFQWMMQKEEKQATKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD22</accession>
    <name>A0A1D2MD22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001764">
        <property type="protein sequence ID" value="ODM90875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD22"/>
    <dbReference type="OMA" id="VHESAHI"/>
    <dbReference type="OrthoDB" id="5960141at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="314" mass="35721" checksum="FD8EC387064A5ECA" modified="2016-11-30" version="1">MGDKKVQWTRTKVHESAHIDAGKGIPESVSKSLRLNQLRQLHKFQSARLRSSQHEASVQPEQGAVRRSADWTSLRRSIQQKSIITELSERLEIEEYGFPEDDEVLNDPTKLEAKLDVTALDRYNEDVRRIRKLTIDECRMLPQKGDADEIMLGRVKLVVRSLCRTVYYGTHKAQVLAEGAVILIVWLLNRRATPVPFKIHILQSFAEMVWASAELKTSLYRCSGMRVIAKIMVTGLHRKSELARWACYVLVISCIGSAEITEAVVDLPYFEEAVGEIAFYAYWSNWPANFGSILQGILYGPHSVVQIEDSCDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDA9</accession>
    <name>A0A1D2MDA9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DBH-like monooxygenase protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_15739</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001736">
        <property type="protein sequence ID" value="ODM90943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDA9"/>
    <dbReference type="STRING" id="48709.A0A1D2MDA9"/>
    <dbReference type="OMA" id="YKKHKRC"/>
    <dbReference type="OrthoDB" id="10003276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.230:FF:000001">
        <property type="entry name" value="Monooxygenase, DBH-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOMON" evidence="5">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="596" mass="68717" checksum="AA25155D82EA7C43" modified="2016-11-30" version="1">MVQEKSRNTAYDSPYTRCQSRAISGFGFSSTGTKWLEQICNGGVDDDGRPIFKDYHAIRNEVPVEDPSQDWTLIEASETGNSTTLRFSRPFDSCDSDHDIPITRDVLSLLWTYSESDDVTQYHFASRGSYEAYLLDPDLTPRGADVEYRRRHPEAAQGLQKLEFQRTKRLPGQDTLYWCTFQKLPFTEKKHIIGFQTVFPDRANFSHVHHMILHRCRAPPGMTQDEFFRGPSESEGTECYILDQPNQSPVPYCREVTHVYGIGGRAIFFPEDVGIAMQEIEDEYWMLQIHYDNPNNSTNLDVTVSLEAYYTDELRENEAGVLQMGDMQPGAHSIMIPPGSINHVIHGHCAPGCTDRILGEVSENGEGVTMFATFLHTHMSGIGVRLMQFRDGQEMPWINYDDNYDFNFQQFRVLREPRQILPKDHILYRCVYDSTDRDGTAITGGFSTREEMCTAFTYYYKASRGFALCRSETRSAAYMNHLGISNYTWQRPIRQMVVTAPEQYAGLTMRDYVNNHIDWTIDYRRELQRLQIYEPQVTQCPRFYWEDGRDFTGPGSDGNTYTSVDPGYEHESTMPRVPRWQRPEQCVAPGSSTRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-03-27" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDX4</accession>
    <name>A0A1D2MDX4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CARD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001686">
        <property type="protein sequence ID" value="ODM91064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDX4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01671">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001315">
        <property type="entry name" value="CARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50209">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CARD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="314" mass="36874" checksum="EFA5E1196F21E54D" modified="2016-11-30" version="1">MEETGKEWILENFSVLLKLTDCNTSFLAILLEKNVLSDEDIQQIKAQNTTYGMAWEVYNKLFARVGSYAVLLHALQETNQTGAVEILNQIHQKSSKRRKNDHDYPLDEIWTKIHPSCLHDYEACINNYHFEMEQVLCRKIISKEKGDLSEDHNRILGDILTRFEKMCDRNPTTQFSPRQIVESKWRLEQALGPLKLEYERKWTENWKLGLESMYLYLDIYKLGIRQQQKTLLLESGKLEIGILDYMENVKSAKDEFRRKFKNLSEDFLNSCLDEMESYASTKLVDVFKLLRRFPFPDAMISHDTVRDPTVVAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME75</accession>
    <name>A0A1D2ME75_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001595">
        <property type="protein sequence ID" value="ODM91318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME75"/>
    <dbReference type="STRING" id="48709.A0A1D2ME75"/>
    <dbReference type="OMA" id="KEEWSAY"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF87">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN C34C12.6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="22"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="189" mass="21840" checksum="E3339FE2085E69CA" modified="2016-11-30" version="1">MDQAEQMLKENLRWRNQTHAEDWSEFREKYPYNLDTINKQGMPILTGNIGDWDLRAIAISGRSSQFIRYIDMIMEDAAETVTQFDFLVNMDNYNVITQGCGQCLQFYIALVNGGENHYPGLADKIVLINSPPIFGLVLQVIRPLMSRTTRESLKVLGQDKTQWTKVLWSIAERSQLRPEFGGTYRRKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEK4</accession>
    <name>A0A1D2MEK4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cysteine desulfurase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001596">
        <property type="protein sequence ID" value="ODM91312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEK4"/>
    <dbReference type="STRING" id="48709.A0A1D2MEK4"/>
    <dbReference type="OMA" id="PYLDIDM"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686:SF1">
        <property type="entry name" value="AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686">
        <property type="entry name" value="SULFURTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="47"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="706" mass="78232" checksum="26A8318BEB5D5900" modified="2016-11-30" version="1">MDDSEMIRRESDSSSIDYPLALRSSLDYAVIGGHQEFAGPFGKRKYVYMDSTASGRSLSVVENFISNHVLPNYANTHTTTSRTSLQTTLFRDQARDIIRKVVGATDEDEVIFCGSGATAAVHKLVHHCLGPRTKPRKLIVFVGSYEHHSNILPWREAASKVIQVPLDIYGNLDLDFLHAKLKVESEKRSKKEKLIVGCFSAGSNISGALTDDILITSIMHQYGGFAFWDYAAAAPHVQIRMNPGCGGFGAKKDAIFFSGHKFLGGPQTPGVLVVKKHVLLNPVPHGAGGGTVLFTTRKNHQYLESIHEREEGGTPDIIGSIRLGLVVRVRNSVGINLITEVEAGYCWKALQHWNTVPEIHILGSSQSPRLPIVSFMIEHVDSVSNPCKLIKLVCREIVVWNLSISCPNLTFGNLIIFQGYFLHHNYVVALLNDLFGIQCRGGCMCAGPYAQHLLGLDDSLASAYESALKKSLNDKWDHITKIGTLLKPGFVRVAFSYHSSPEEIDFVIKAVAMIAKIGWKLLPMYHMAPDTSVFTFNGRKVCMLLNVLQLGKSHSPDMGSSFPSGTGPIDYPMVLKEAHSIFQKVPKLFHVNQPVQDEFDELLNVPEAKTLKWLLTPLDSLILQTTTKSGAYIKSSKAFSPRKPYYANSLNLLAHKGSIPRMIMKAWLNDDLQEIPPEHTISDYYPTCNLVSDKDTASNSMTRQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFL7</accession>
    <name>A0A1D2MFL7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001423">
        <property type="protein sequence ID" value="ODM91780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFL7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="18951" checksum="222320F15FA2630F" modified="2016-11-30" version="1">MAKLLASWKGLGKSESKEEARIARAIAKNNGRPHLLATNLNTNGNLFNQNRRHSSCILDGSDGASKLKPIVPLHSIGKENMATSWRKTSQFDLNKSTGPVQPFRHVQPNLRTEINHAETPKPKPSEELNITLGEARCTETNGNNGHSNGGPTSVAQKPIPFPRKPGILYRFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFP1</accession>
    <name>A0A1D2MFP1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-retinol dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.300</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_14881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25033"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17336"/>
            <dbReference type="ChEBI" id="CHEBI:17898"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.300"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor metabolism; retinol metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.300" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001415">
        <property type="protein sequence ID" value="ODM91806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFP1"/>
    <dbReference type="STRING" id="48709.A0A1D2MFP1"/>
    <dbReference type="OMA" id="VMRCPKS"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052650">
        <property type="term" value="F:all-trans-retinol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000145">
        <property type="entry name" value="Retinol dehydrogenase 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="36750" checksum="B0165DF829800C7C" modified="2016-11-30" version="1">MAKFPRFMIITSGIGAVVGGAVLLKDFIIGHGHKLPDTIRADGKVCIVTGSNTGIGKETAMELARRGCRVYMACRDLEKCRTARAEIISDTLNQHVHCRKCDLADFDSIRQFAEEFKAKESRLDILINNGGIMRCPRTLTKQGIEMQLGVNHMGHFLLTNLLLDNLQSSAPSRIVNLSSIAHTRGTINFEDLNSEKSYDPGAAYNQSKLANILFTKELAERLKGSGVTVNAVHPGIVKTELGRHMGFENSITASIFVKPILSFFLKSPVQGALTSIYVALEPSLESTTGKYFSDCKQKEPSEQAKDPTLAKKLWATSEKWTRLNSNSPSYSASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG01</accession>
    <name>A0A1D2MG01_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001406">
        <property type="protein sequence ID" value="ODM91831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG01"/>
    <dbReference type="OrthoDB" id="3561125at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="203" mass="22752" checksum="258B02D84A34158B" modified="2016-11-30" version="1">MLPSRRVRHNPRNLNNPIRAPGVDNLTGFEELNFWGTLMTIGMLVYLVSWKYSILTNNVSGHLDLAIEQNDIPAVGEDAKTKPLIPEPVNAWRLVYFFNIVTIVVGSSFLLGEVRRAIRQFNFDEEAAGNNSLIYDILLGVLMLATIGESVVWACVVATTGYEIPPYVYSSFSCSGLLIFSAVNFVEDIQLRLRIGRGTERRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHF1</accession>
    <name>A0A1D2MHF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Cell division cycle 5-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_14332</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001256">
        <property type="protein sequence ID" value="ODM92351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHF1"/>
    <dbReference type="STRING" id="48709.A0A1D2MHF1"/>
    <dbReference type="OMA" id="CVAMGNE"/>
    <dbReference type="OrthoDB" id="1410009at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000091">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="17" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="16">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="15">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="15">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="16">
        <location>
            <begin position="59"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="111"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="772"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="660"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="775"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM92351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="799" mass="91108" checksum="573AC940D9E19A89" modified="2016-11-30" version="1">MPRVMIKGGIWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWFEWLDPSIKKTEWSREEDEKLLHLAKLMPTQWRTIAPIIGRTAAQCLERYENLLDLAQKKEEGDEESGEVITGKGSAARKFQAGEIDPNPETKPARPDPKDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLASLQKRRELRMAGIDVRMKRPNRRTLDYNREIPFEKVPAAGFYDTSGETFAVKDPAFKQLRQEQMEFQMRKEKESHERAKDKAKLNKWKENEMPLSLMMDEQPQRKRSKLVLPSPQISEGELEHLVKVGKAVEAAKDGAFESGTQASRTLLNDYAVTGGGSLLRTPRTPSSTTDRIMQEAQNVMALENLDTPLKGGVNAELGEVDFSGMTPKKLGETIRTVNTVLASPFIRTPGQSPFCDTPGKAEGVASTPVRDKLSINIEDGGLVASSKLKEQLHSLPTPKNDYEIFIPEAELMETEAGEKSGGAQDRVADQDDLDQQTLAEKNRSRLEEFKKLSQAVQRNLPRPKDVNEGVLRYPGKDELQQAEKLIKEEIVIMLHHDALVAPAENQVVTKGKTGMSSVFNQAQHLDYLEEHPYQEFSEEEMAQAKQLLEVEMEVVKKGMGHELSFQMYEKVWDECLSQMLFLPTQNKFTRVSLASKKERIESLEKELETNRGNMMKEAKRAGKLEKKVKTLTTGYQRRAHALVGQLNELGEEIDKVKMQKDVFEFLKVKEDAAIAHRLQSLTVDVDRQMKRGKELQQMFSKMKESVTEKEDWNENKENDDPNKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHJ1</accession>
    <name>A0A1D2MHJ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Annexin A6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14308</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001250">
        <property type="protein sequence ID" value="ODM92372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHJ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MHJ1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0041">Annexin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904035" evidence="4">
        <location>
            <begin position="25"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="837" mass="97202" checksum="2A5DBB3BB6C68DA1" modified="2016-11-30" version="1">MAQINILITLVLMVTSVTLQYTDAFKNYHGCELHDNQPGHPTFVDIPNFNATADADYVWEALYHGGQDMIIHLAHLGSMRSRNQRKQIMKTLKRVHNVSLIYDHLHERTFDGTLGALVRALYMSREEFFATEVRWAIEGPGTDENTLTDIFCCLDPQEIQAGDIRRAFSRLYGSPVDYEIERDVCLDTYGKLLKELIMEKRSNTTDYDAAKTNAKLYFEDSKTEDFLHLSENSTIAYWKFFARRSYKEISMTSKNFNEISEDKPPFTKYLARVTTMNWWKFFTKDFWKIFPCGGNFRELVLAIVNYSTDKTKYYLDLLLDGLMVGDSRRLIRIVALRADKDLELIKQRYSENFGGIQGHTLAQLVVEQQHPFMHNHISHQVRTLLFKIICGDLYVNQHLDQLGDVLDLSTAVSIVIIVCIQFTDARTGENYVIRPGKPTLVDLPSFNKTADTDFVYKHLTRKKGYTVRHLAYLGSLRSRNERKQIVEELKQTYSIDMVHDYLLKAAFDTPDGALVRALFMPRDEFFATEIKWALMGLGTDEDTLTDIFCCLDPTEITADDIRRAYERLYEGSLDHDIAGDVCVENYGKLLDELVTKKRSNKADSDVAKSNAKLYWEDVKNKDFLHLPESSSISYLNVFARRSYDEIRMTSNNFYKLSKDEFPFTEYLDRVTSKNWRNFFSQDFWTLVRCGANFHDLILAIVNYSIDKYDYYLDLLKTALEEGDDRRLIRIVALRADKDLEWIKQRYTEDSDDAFSHNLAELVREKYTKFFSDRLELIVRFLIAEIIVGNQYSQFHSSTSNFEVHGKIGVTKAEALWEIRKSRQATAMRATVAWSPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHU6</accession>
    <name>A0A1D2MHU6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001204">
        <property type="protein sequence ID" value="ODM92545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHU6"/>
    <dbReference type="OrthoDB" id="6363067at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011015">
        <property type="entry name" value="LEM/LEM-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003887">
        <property type="entry name" value="LEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03020">
        <property type="entry name" value="LEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00540">
        <property type="entry name" value="LEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63451">
        <property type="entry name" value="LEM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50954">
        <property type="entry name" value="LEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="LEM" evidence="3">
        <location>
            <begin position="21"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="33703" checksum="E51CF855EA214FD6" modified="2016-11-30" version="1">MFISDDIHRLVVNLGYESRREKWVARLSDRNLFDALTACDRNVGPVLDSTRDLYRKMLIDLLKTGSTSQIVESIDNHLGSNQVALEHWEKTGMQSYRLTADDRSTDDEGDKSDKSSNAGSDVGSRRRTPTPSRGLSYASALSRESRAAAEEEFVRESTPPVTIPRTPRKLSSPLSAPSWPDLGAASAAEQEKKTESCQIKTGSFDDGFELRKREKGGSQVRECTKDVQGNSETGRSGQAHVSNLKILILALICGFSIFFAIFYYRENFYGSGPSQAEIEMEPGFKDELDYLIEQVNNIGGAEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIF9</accession>
    <name>A0A1D2MIF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase D7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13919</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001155">
        <property type="protein sequence ID" value="ODM92759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIF9"/>
    <dbReference type="STRING" id="48709.A0A1D2MIF9"/>
    <dbReference type="OMA" id="FESHVIC"/>
    <dbReference type="OrthoDB" id="8183779at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03177">
        <property type="entry name" value="GST_C_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03045">
        <property type="entry name" value="GST_N_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000034">
        <property type="entry name" value="glutathione S-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000007">
        <property type="entry name" value="Glutathione S-transferase 1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969:SF2">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D11, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01153">
        <property type="entry name" value="Main.4:_Theta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="86"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="24611" checksum="F9C3E324816490EE" modified="2016-11-30" version="1">MGIELYALQPSVPCRMVRLLIEYLELDVDFKVVDILKGEQLDPEYMKINPQHTIPTLVDDGLIITESRAMLMYLGNKYAENLYPSDSAKRALVDMRICFDLGTLYVRFMDAFWPVMYDQIMPDPVKLARLDEGLGYVEDFLKDGFIAGSELTIADFSMVAILTTLKAMEHDMSRFSEIAAYLEKCAGMMKGWEEINQPGADTFGQWYKAALAAAEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJG8</accession>
    <name>A0A1D2MJG8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Platelet-activating factor acetylhydrolase IB subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001052">
        <property type="protein sequence ID" value="ODM93177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJG8"/>
    <dbReference type="STRING" id="48709.A0A1D2MJG8"/>
    <dbReference type="OMA" id="WAQRHAQ"/>
    <dbReference type="OrthoDB" id="505607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852:SF0">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="41"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="370" mass="42387" checksum="9A548E80DE1DF100" modified="2016-11-30" version="1" fragment="single">STLGQKPWEPTEKNEAWWQERHQEILNTTASLAKDIKVVFIGSSSVEYWGTTAKEIWDSKYAPLGAVNYGIRSDRTEHVLWRIQNGELDGLSPKLVVVYIGSNNVPLFTEAETVRGVDAVIDTLHAKLPNTNLLFLGFFPRGDRTPVRNTLTKIRNITDTLEPMLDGDTQRKAHFLDIFWSLAPQSLDRIYEEFYRDDKLHMNLEGYKIWDNLMNRVLSQKPWDSVERNEDWWKQKHQEILNTTASQAGQIKIVFIGSSSVENWGSTGKQIWDAKYAPLGAINYGIGGDRTEHVIWRIDNNNSEIVRGVDTVITKIHEKVPSANILLVGFFPRGDMNPVSDLLRRVISISDTLNHGGWRFPKEILLFRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJK7</accession>
    <name>A0A1D2MJK7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cation channel sperm-associated protein subunit gamma 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001074">
        <property type="protein sequence ID" value="ODM93112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MJK7"/>
    <dbReference type="OrthoDB" id="9949093at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036128">
        <property type="term" value="C:CatSper complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097228">
        <property type="term" value="C:sperm principal piece"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028246">
        <property type="entry name" value="CATSPERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053873">
        <property type="entry name" value="CATSPERG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053874">
        <property type="entry name" value="CATSPERG_Ig-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14327:SF1">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14327">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22846">
        <property type="entry name" value="CATSPERG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22851">
        <property type="entry name" value="CATSPERG_Ig-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1817"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="domain" description="CATSPERG Ig-like" evidence="4">
        <location>
            <begin position="1511"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="domain" description="CATSPERG C-terminal" evidence="3">
        <location>
            <begin position="1647"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1892"/>
            <end position="1929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2029" mass="233146" checksum="1D18512DD554A9D7" modified="2016-11-30" version="1">MRPKHRRGESLYIAAAIIEIEGEKRLEELKDLAPSPVTDPFGVISQPGFQYPCEYKCESDPLYWTCVAECYERDPTALWDSQCYKTNLCNSSAPNHLLRGRCLPCLTQSTLDQLQKTCEIAYLPNSAPGINNLCIEMERCINKVPTPGSPGGGVNRTIRECAMDPQVQNRKELMQLCVTDTIMSAQRDCCYSEPVREASLCKTNNHKCDEFCDRILSPRLCQATCKKIRDEAQHECLENTCTFDYPISKVPCVHCLDSSLLTLKTHVEACTFPFCIRNLTTTKETYLTDNCHNLDWIQRFASFLKTKLNINNDIWAKVEVEKMDWITSHFTPIECFNDSMTDPLKGCAEDYLTTKRDSPDILAKCESNPYRILDMLVCGLHQEESLSWMNVLNQRNKFTGIRCKNEKLTLEVYKLVFQYEEKVCDDYCAKSKIRPENVASMKCRLEQCLVKEENLKVEHRKHCKPLEDAYLVQVSDFAPCRWQVDFAKSSNPYVLYATYFNELGPSEIRDKLEHPDTTGILQETDVNGKEGFYTFPYFVVVRVSCCTFIQPEPESLCDDNGYYDDGAYRFFVVGGNPIVELKYTAPTSRHSPTTLIHGVFQSSLVKLNSKGNDELIPLNPGSVDEEGNGCHEKICHPGFVVPLILLNIPQETMYVSAFHSRAVEGKGEIQIATSDYPAHAGMLFPKKRSSIFTDIELSFHSSCFANDLSDSTSEGYKKLKCSELDHILDEFDHPYETNIFAPLDAEDMLRSQYTYDNRTVQAIAGFYDPRFLVIGDPDMNDFEVVNWGKLLKPLEKDTSLHSCIQQDLVHKGYPKPIYSQIDRTDPDYPIYYRQRYAGRVYYDEKANKKSKEEDLPETAVFEAIALEDRLLLVTTKGLVSVYGHTNATVATNRQWTFSTDPARQDQIDRCFKLVRVLRRAQPNSDTIVGITYDYRVRNPTTKELEEVTQQVWVGKFTYPGQNIEWSKVEAVSVDNNIESHRVLDGAEAKSPGDPVLFDPVKQPGLPLQIREANPKSPIETICYKTYRTVIQPVAPRATVYDDRGWCQVIDATPEVMKELTIQVLVRFRLMYNEEGRDIIPVYFYILATHTLKQNSSVGFWRIDAVIPRKPCLDQHHESIKNTFLFDKTYFIHKTVGTGQEYGCYDDGNRKEKYIDSYVYLTGMTYTRHAKTIIKWQKPLCSLYAVHQWYCTIRLSAQKIRYELWLVEQPQVLGVVEVFHREVHRIMLMAFNDKGHYAFLTNKLELWVGNTGSLELILLRPSPLRGMVQLGLSKVRNLHDGVPFSIHFDSSDSLYEMVAIVGKEGHVTRIMKRPATEWKLLRVQQRAKDKAAGLSKELQMSFNYDSSMWANTCPFSSPKLSQNFSSTNSRTQGMYFPNPRQHLKLGKAYIEASLMTFQAATFSLVWKSFYNVPIRYYTGKDKDAFELYVFNKYNFDTEFHPKWIDKKRDMAILGVLQFGQGEPEDTGIVVQPRKFKRLQSYGNSSNLENSYYIDYNQVAELRLEFSSKNDFMVLNTDYEAQEINAIQLNVENANGSIIQVNTDKVFEAHRAVVVFFVRISVKRKTGLSQNLPGEHLLPVPMTFHFIGAFGNCIKNRANGIIGDSVETVAYVGCPPSRDFVFNWKSTLKSLKFRSGDTNHGTGDMCHGHEFACFFSRNPLVLFFDIFDESKQKFIPYTGKYTLRIIAGGRTKDEMRMFTDEEIQGYNVPGISDVSLIWNEWDITRHQKVERKPQTLYDDDGQEVHRDSREVILESGKSTILWACHTLSPCARVRPTWNLEVIFWFRLQITNRDVDNDTLCLYEKEIDIMLYGFNPSPEFQLFSTLGFCFFLLTILYICYRCCRRHQYLWRATKVNVRSWIRITKEVFPKKIRKYEPPLPEEVLERRQKVHRGFGSQDITHGDDDSNASLVDADSQEGGNKAHSSASSVGSLSTSMADSSQILPDNRPQYLPLSAKGVVYDQILTRRLNSIVERNRAMRQNLIRKASIQLKVDDLETEAHFEAQFGRTVSQESVFTPPMPKDRKRGVDNFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKI8</accession>
    <name>A0A1D2MKI8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_13095</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000951">
        <property type="protein sequence ID" value="ODM93586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKI8"/>
    <dbReference type="STRING" id="48709.A0A1D2MKI8"/>
    <dbReference type="OMA" id="DYQMFLR"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10324">
        <property type="entry name" value="SLC6sbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM93586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="584" mass="64929" checksum="C4487CCB1254D01E" modified="2016-11-30" version="1">MSNSLHHDNKGYEKDESENDRKSSALPDYTVAVIDSAPKIYLPRVIIGNKVDGNNGQAESSTPTYAVDVTAEQASETTDGVPGDGRDTWDNPVEFLLSCISMSVGLGNVWRFPGVAARNGGGAFLIPYLHYTFARGRPLYYLEMCMGQFSRFGQVKVWNMSPIFKGIGYGAITGTIVTVSYYCSLMAITSYFLVASFAKDLPWSVCDDTDKDYNCTLIGPEICRQLLQANIDDGLGKLHWKLSLCLVAVWLLVFFTLVKGVKSSGKVAYFTAIFPYVVLIILLVRGLTLKGAWEGIKYFITPEWSALYKPKVWYAAVSQCFFSLTTAFGPIIMFSSYNPFKQDVYKDALIISFVDTFTSLLAGCTVFSSWMTYPQAIAKFGWAPQFFAVMFFLMLLTLGLGSAASLTGAAITILCDQFPKWKRWLVTLVVCTSLCLVGLMYVTEGGMLMLDLVDNYGASFIIYVMAMVECGAISYVYGLSNICDDIEFMLGRHVGIYWRVFAAGYVTGLRSDLYTSMGIHTVATRKAKSLKEKIIEASKPTHRWGPQDKQLRSEWLAFPRRKAFTTLKEKISDILGIFLLGVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKZ4</accession>
    <name>A0A1D2MKZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monoacylglycerol lipase ABHD12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000933">
        <property type="protein sequence ID" value="ODM93686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MKZ4"/>
    <dbReference type="OMA" id="WFKDLNV"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052651">
        <property type="term" value="P:monoacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006660">
        <property type="term" value="P:phosphatidylserine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF194">
        <property type="entry name" value="FI04476P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="362" mass="41198" checksum="460D10D5CC588605" modified="2016-11-30" version="1">MGLRALFMGITTSAVTILMVWYYEMQLHFGFKIAVGATLLLYLLIPILYHFNSSVQRHLVFLPFVRWPAGINFSDPDSQGLQGCRNFYLMTQEDVTVGVWHMLPKSLIQQSKGKESQFWEDSMRNSGKHVIIYFHGNTGSRAVPHRMELYLILQQLDYHVVSFDYRGYADSTQIPPSETGVVTDGYAVYKYVRSILGASSVSSHVVSNLCKEGDPPTALFLESPFTSIGEEVKHHMLAAIYRYMPGFDFIFVKPLHRNDIAFESDRHIANIDIPMIIFHATDDPVIPYFLGKKLHTIAKRKRSSSAKPIYFKGFGEGFGHKYIYRSPELPQLIRDFVQCACTNQWPCPGFNKSDSADVLAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLS0</accession>
    <name>A0A1D2MLS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000912">
        <property type="protein sequence ID" value="ODM93794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLS0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="697" mass="76137" checksum="BD98AF6349DF5474" modified="2016-11-30" version="1" fragment="single">LITLNISVFAPQLEHYHHHSTFRIFFKNMLFFLKNFSIYFLLQVVVAGSSASQDVSEGHNIQKRYSYPTTPNYYQGSTYPQYNQNATCPPPKPYPLDGCNCLNCTFDTRPCTKDVHPTGCTVQYCTADDTFLLGYTCWCGGPYFPGGCMDENEAGKIRCTTDTSNTCYCNGISKCRTFSYIDVCMAGEQPTCSTTCLCHPTEPTRRPCGCVTGTIRSSLDTNTLAEQIQAILDEQEFEQNLNLMESSFTSSFPNDPGSHKIQKRYSYPVAPNYPPGASYPVAPNYYPGTSYPSNYQATTCPPTNSTPPVGCDCQNCNFNTKPCTKDDHPTGCTLQDCTAADTVLHGYMCYCTASLTPGGCVRPNVAGKTRCPNYFAPDCYCNSIGKSGTNCYADVCAVGEKPTCSTRCLCHPTDPTLKPCGCVTGVIASGGTLAAEVEAILAEQEREQILNFIESSSANSFPFSAESNHYEFVNQVSKDVSEGHNIQKRYSYPTTPNYYQGSTYPPYNHNATCPPPNPNPLEGCDCLNCTFDTRPCTKDVHPTGCTVQYCTADDTFLLGYTCWCTIGSFPGGCMDENEAGKTRCTTDTSTTCYCNGISKCRTFSYIDVCMAGEQPTCSTTCLCHPADPTRRPCGCVTGTIRSSLDANTLAEQIQAILDEQGFEQNLNSMQSSFTSSFPASTGSHNKKAGLLNLLLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM34</accession>
    <name>A0A1D2MM34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tight junction protein ZO-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000858">
        <property type="protein sequence ID" value="ODM94110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM34"/>
    <dbReference type="STRING" id="48709.A0A1D2MM34"/>
    <dbReference type="OrthoDB" id="418634at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005923">
        <property type="term" value="C:bicellular tight junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045216">
        <property type="term" value="P:cell-cell junction organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0150105">
        <property type="term" value="P:protein localization to cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06727">
        <property type="entry name" value="PDZ1_ZO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13865:SF28">
        <property type="entry name" value="POLYCHAETOID, ISOFORM O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13865">
        <property type="entry name" value="TIGHT JUNCTION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="101"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="306"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="673" mass="75395" checksum="3DFDD3CD326AACE9" modified="2016-11-30" version="1">MPEESPFPFRTPMIPPPYPYYDDTNYVSSSRSRQNILNIMLNELELELDSNTDTNVTETNTNANSTLERTELRASCTLVDSTILEPDELTSTVSRNWEYVNVSLTRVPGYGFGIAVSGGCDNPHFANGDPAIAISDVLKGGPAQGKLQINDRIISANGISLDNVDYSTAVADPAKRIKKLNFESLGFTISVTLQIKTVDSPALGLREGDIIDKIQGLRVNELFNEKIVVKELKRVVDESSNGNSGTLNLTVKRSGSHRTAQPQQAQTPQPTLSTGNLYVQPPTRNNKSFDNTNVNTPPPPPPPRPPLPVEFEAKNQLGIRLSGGNKTGIIVSAVQKNSQAELQGLSNHDKIIRVNEHDFMQNPPTRENAIEILSSIPNDTLVNLTVERSAPIPLHINQDEFYIRTRFQSDDFKIHELLLVTDTLVNGMVGHWEAYRVDSNGNALKHEKLIIPNVKHARDMLKKSWKRTTSFRNREYEDLLACSIAVDPYDNIEKILTHDLSKRPLIMFTPHNPSVVDSLSNLKNSSRVFKFIKSNDRLEFTDQRVRVIQDYVSVKYVQELHEKRIYPIVMVCNFPNKETMKDAIRDASKYSKSKKMFNVMGKLDGKLGSYADLKHEASDFESMAQWIYRVVVERGDAVSTVFAKVNDSVSFTNMQSNVALESNEEFNASSPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMB0</accession>
    <name>A0A1D2MMB0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000845">
        <property type="protein sequence ID" value="ODM94190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMB0"/>
    <dbReference type="OMA" id="HEHRTYH"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904249" evidence="1">
        <location>
            <begin position="17"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="153" mass="16433" checksum="BC2D0D14284D1CA0" modified="2016-11-30" version="1">MKVFIVLAAVIAAVSAGYLGHHGYGGGHLGGHHGGYGHGHHGYAAVPVAVPVVHKVPVATSYHHEHRTYHPIVPVIAKVPVVAKVAVPVYPVHHGYGHAHGGHHGYGHIGYGGTSSWRSWRRAWIWTLLKTVGITSSTLQFVTLPFKLTYNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMW6</accession>
    <name>A0A1D2MMW6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative N-acetyltransferase camello</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12309</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000816">
        <property type="protein sequence ID" value="ODM94367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMW6"/>
    <dbReference type="OMA" id="TYFSFYA"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="98"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="30505" checksum="0CAE3FB75DC34596" modified="2016-11-30" version="1">MESPIIVIRPIREEDCLAAKRVVFEGTLEPVNRFFFKSIFRETCAQAMVMVAALLYIVVGVKFQYCFLAIPIVIITTYVGVWTAHYYKAKYLHHDMKDIMKTYMSTDKNTCFFVAEALYSPENKNRIPAFVSDIEFNKMNWNGFYTSSPDISKQIVGTIAIARYKSSSVIAWLRRTAVKKEWRKKGVGSQLVDAVIRFCSQKGFVGIELVTTECHDSAKVLYEKKKFDTMAFYHKKLLNYTGLYITMYVMHYKTAPYSKTSMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNE4</accession>
    <name>A0A1D2MNE4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynamin-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000797">
        <property type="protein sequence ID" value="ODM94513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNE4"/>
    <dbReference type="STRING" id="48709.A0A1D2MNE4"/>
    <dbReference type="OMA" id="ENALECR"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="3">
        <location>
            <begin position="91"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="700" mass="79099" checksum="55C2F4FA142DCC1F" modified="2016-11-30" version="1">MHWNRSGDSLTTGHCFVNQLFFPTLLPSSSPWLTMPKMSFPSLTIRSLGIFPNASKPKSGLSSIMPDSRGLIELVNKLQNYFKSNGLGTRKIELPQIVVVGSQSSGKSSVLDGLVGFSILPRGSGTVTKCPIIVQLITTDAGKEEEGIELQDFLEDGRSQDYDEVRAKIATLMERNGGAIVDTPIIVRVYSPNVVTLTVVDLPGIKRIASYGEPSDLDKRIVSLSRKYINEKNAIILAVSPANYEICNSEGLLLAKEADPEGNRTIGVLTKLDLMDEGTDARGLLTGMSKDVQVKLGMIGVVNRSQKDIENNFTVEQQIAKEKSFLSNNYGDLIGQNGVPFLRKRLNELLVQHIYKCLPELMEKLEDMLKQCNKQLTEIPNVMTETDKLEFVIKVLHRFENEIKKEIQGSPRTPEYHHLYGGIVIKDIFEKHFAKDMEAAENTSDGSITDSMIFKAFRNSGSYDSMFLNPEAVFRKLAQNQIHHIEGPALKCAERVYDEIMKIADRNLAEENDHAFKYFPELRQLFKRVINHILDENLDELKKQIIEYIRVQSSVVFSMDYKFLQRDCRPSEELEKELYVGDGENSSDTKMSQVVPVVETGVKLYFRWIKSHVQDYIPKLVTDKLIIPFTNDAGFGVALKVSVMKDYKTLIQLPENALECRERDLILSEHLVEVIAEVKEMLNSCNQKDHEKLYDDDDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNH7</accession>
    <name>A0A1D2MNH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chymotrypsin-like elastase family member 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000809">
        <property type="protein sequence ID" value="ODM94404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNH7"/>
    <dbReference type="STRING" id="48709.A0A1D2MNH7"/>
    <dbReference type="OrthoDB" id="5565075at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904322" evidence="3">
        <location>
            <begin position="22"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="89"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="294"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="578" mass="63438" checksum="BFBAB30E7BCA7B2B" modified="2016-11-30" version="1">MKNFILVSIGLCALFVDSAVSQCSQELCLAPHWMCNKAVPDYPHSVPSSNKDTACTGDSGPGTLLWQGQSWELRKTNILIKSISELGACVAAQFTTKNWIISAAHCVRYGNDPNNYTSKAGQFRWQPGSEVQQAFVIAGTSHVKDADVPEANRYPIDKVIWHEKWNPNEIGDGYDIVLLHLKRPLDLAKGKIQPMRLEPANYVPNYGGNGVVIGFGNVNEQLGQASDDLMEIVGPIHHPATGIQMSFDPLNAEPSGTDLKAMHLAIGGGDSGVIVGQGDSGGPFICGDKNNKPILCGIASFKSCAPFKFCRKPSYFQRVAPMLQWIKDNTNNEPQEEELFFDEPLFPSKVSNEKAPASLVRIIHNKVSCMGVIVTSKMILTTAACTKNPDLSKANPIIYHFNSGEVLPYNGGGTHPDFTPDVSKNVSHYLTQPLNRNDFAFVAIKTPVPAAYVAKLAPQGYQMKGRSVEYTFNQAVNSLEKRNFLEMDKTDCASKLRAVDKKLELTPDQLCMRQVYSAEKDCKRDLGGLLMCDNGKFFCGLGSFHACKANGFPEIFANYLTGRGTLRAMLDRTMQQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNJ5</accession>
    <name>A0A1D2MNJ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sperm flagellar protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000807">
        <property type="protein sequence ID" value="ODM94424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNJ5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010441">
        <property type="entry name" value="CH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06294">
        <property type="entry name" value="CH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CH-like" evidence="2">
        <location>
            <begin position="35"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="277" mass="32133" checksum="2A82F826B089EB9E" modified="2016-11-30" version="1">MNHEGAVGVEDEHYFLNMWDSQMQDAGEDTMTETLMQWFSTIDILKHVGANDICGMFSDGVLFVLLLRELSIPEVRHVGDNYLAPVNTFKGKLHNWKILNVEVLQKLNLGVTEWYLEFIAREKKGYAEAVLHSLYQLVQEREKVRPQKRNWKTPSDNSPDARPLDMESVIWGSGTRNRRQRTRNRKAPVVKRYFNSGGRRNRESTGRSVLGEHAVQTYCLLAKKRKQGYPFGIPNLRGRNSYAKRPGYLTYIYKYYVQFPHNCVFCNSIEKCACTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNQ4</accession>
    <name>A0A1D2MNQ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000772">
        <property type="protein sequence ID" value="ODM94667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNQ4"/>
    <dbReference type="OrthoDB" id="6429739at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="28026" checksum="CC924F2C40762025" modified="2016-11-30" version="1" fragment="single">EENDVHAVVIVNKKRERLERKIVFKELRKSNKCVSESVSEGARSLLPSEKRQKEQDCAILIVLPEPNNDVNRHHRASSRGNTRIYDINPGVAGAALDPRKPWFRGAIPPPGITATTAPAGEPSFNSLCESRLGEDSLFSYGYGVQPREDTDASDEVLTRIRSGVMRDSEVKHSPGLFQYSEMPSLTRSTPPRAFGNITTEEDKNSVFKGYLTAILSCIYAIFILMLGVVVYIADLISRTATLAECDSLPWEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNQ7</accession>
    <name>A0A1D2MNQ7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mannosylglycerate hydrolase MGH1-like glycoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000763">
        <property type="protein sequence ID" value="ODM94720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNQ7"/>
    <dbReference type="STRING" id="48709.A0A1D2MNQ7"/>
    <dbReference type="OrthoDB" id="8248091at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054491">
        <property type="entry name" value="MGH1-like_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22422">
        <property type="entry name" value="MGH1-like_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannosylglycerate hydrolase MGH1-like glycoside hydrolase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="225" mass="25850" checksum="C87E874A6EF3B7EC" modified="2016-11-30" version="1">MEHSASSEQTDDPYHGGLGYRPSFNSEMYANAITISKIARINNDTRTAEEFEGRAAAIRQGILDHLWDDERTFFYHVFREDNPNYELLDTREEIGFYPWRFGVPDPQEPKYALAWEHLFDPQGFNSTYVQQLVNKDLYGLMEIKRHSVAGGMVINSLAAQLRDYGTTNIVNVNTFLEVLHNNHSEHYAHSTYVDNVLGDLIGIVPQPDNIRYQPADTIHLALFHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNR8</accession>
    <name>A0A1D2MNR8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NEDD8 ultimate buster 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11999</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000769">
        <property type="protein sequence ID" value="ODM94677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNR8"/>
    <dbReference type="STRING" id="48709.A0A1D2MNR8"/>
    <dbReference type="OMA" id="SVCRLME"/>
    <dbReference type="OrthoDB" id="434245at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000058">
        <property type="term" value="P:regulation of ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14270">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14291">
        <property type="entry name" value="UBA1_NUB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17062">
        <property type="entry name" value="Ubl_NUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039749">
        <property type="entry name" value="NUB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041207">
        <property type="entry name" value="NUB1_ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12948:SF3">
        <property type="entry name" value="NEDD8 ULTIMATE BUSTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12948">
        <property type="entry name" value="NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18037">
        <property type="entry name" value="Ubiquitin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="124"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="370"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="442"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="67541" checksum="DF6E3CCBC9124C6E" modified="2016-11-30" version="1">MSATNLAENALTARLRDRLNLESMKLWLEPFFDPVTQAPKDTEVVALGSRYAVELELAESEVIQCLFALQQHAIEKIAERQTFKSTGKATLRIRYSGQLTADEKKVALNVPKLQLNLAATNGKDLKDMIAEKLNVAGNRLKLISAGRVIDENKMLEAQNLKNGSQIMALFISTDKETYQETEDRFKQLEDIKDSADYLASSERSDVYTLQVADQSGKPLDLPEAERKALAVALALHDKGRAALKIQDFSKALVFLLEADTVYSQCQSQLLEMVDNYGLLNLDIAWCYLSLQSIAELPEAEARLQKCERALRRSYGEDMERVVALKGSTGWEAALFVRLHLLQAIAAYHLGQIEKSRFLMTRAETELGRLKVSDDKLAELINMGYKEEESRMALRATYGDSTSAVDWIIRRREEKSQIKQQEKENRERRKLQKQLGNCDNDQPVNTRLFLQMKEMGFSPTMVTFALKRANNDMNIAIQLLGDDEFLRQARANIVIPSTQDGPSTSSAANADALAASVATVASAQGPAATASQQELLQNLADQLFENNLQDEFSMMNEAEKEKSQKAYESLTKDTCSESEYIDLTLSAEAEYLEHYKTLITTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPZ2</accession>
    <name>A0A1D2MPZ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine/tyrosine-interacting protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000744">
        <property type="protein sequence ID" value="ODM94825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPZ2"/>
    <dbReference type="STRING" id="48709.A0A1D2MPZ2"/>
    <dbReference type="OMA" id="CINPNAR"/>
    <dbReference type="OrthoDB" id="426001at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="98" mass="10897" checksum="6A762CF2BE87CAF8" modified="2016-11-30" version="1">MDSDTESIIPHFKTVNAFIDECLSNGGKALVHGSTGNSRSAALVLAYIMSKFGVSLNEASSLVKSKRYSIRVNNGFMDQLREYEPIYRALHSVPDKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQM1</accession>
    <name>A0A1D2MQM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Suppressor of hairless protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11270</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Su(H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000677">
        <property type="protein sequence ID" value="ODM95410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQM1"/>
    <dbReference type="STRING" id="48709.A0A1D2MQM1"/>
    <dbReference type="OMA" id="HNTSAWI"/>
    <dbReference type="OrthoDB" id="5600360at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990433">
        <property type="term" value="C:CSL-Notch-Mastermind transcription factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01176">
        <property type="entry name" value="IPT_RBP-Jkappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1450:FF:000001">
        <property type="entry name" value="Recombining binding protein suppressor of hairless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000003">
        <property type="entry name" value="recombining binding protein suppressor of hairless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000074">
        <property type="entry name" value="Recombining binding protein suppressor of hairless, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015350">
        <property type="entry name" value="Beta-trefoil_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038007">
        <property type="entry name" value="RBP-Jkappa_IPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09270">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20144">
        <property type="entry name" value="TIG_SUH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01268">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01267">
        <property type="entry name" value="LAG1_DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="12">
        <location>
            <begin position="44"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-trefoil DNA-binding" evidence="13">
        <location>
            <begin position="176"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="459"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="523" mass="58612" checksum="AB449BD3B5B0A987" modified="2016-11-30" version="1">MLSWNSFSSKMNSSRCVDSDGSAGKQRLTRERMRKYLKERKDCVLTILHAKVAQKSYGNEKRFFCPPPCIYLEGDGWDRKREMMLAQGETELGAQLCAFIGIGNSDQDMQQLDLNGKNYCAAKTLFISDSDKRKHFMLSVKMFYGNESEVGVFHSKRIKVISKPSKKKQSLKNADLCIASGTTVALFNRLRSQTVSTRYLHVEDNNFHASSTQWGAFTIHLLDDDESESEEFNVRDGYIHYGSTIKLVCGKTGMALPRLVIRKVDKQMALLDADDPVSQLHKCAFYMKDTDRMYLCLSHEKIIQYQATPAAKDASREVISDGAAWTIISTDKAEYQFFEGMGSVPTPITPVPIVHSLNLNGGGDVAMLEINGENFGPQLKVWFGEVESETLYRCAESMLCVVPDISLFREGWQWVRVPTQVPVSLVREDGIIYATGLTFVYTPEPGPHAHVPSIDQVMRTPRNSTAPSTNNSYHSSQQQLQQLHNSHSSSHSHASPANMELHGMSPVGNAGIKYSYSLQRSMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRA4</accession>
    <name>A0A1D2MRA4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein SMG5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000658">
        <property type="protein sequence ID" value="ODM95526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRA4"/>
    <dbReference type="STRING" id="48709.A0A1D2MRA4"/>
    <dbReference type="OrthoDB" id="5920073at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF7">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="550"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="777" mass="88397" checksum="822A24CCAA39009B" modified="2016-11-30" version="1" fragment="single">AFLLRPDSGLAFNQLGNLYADVGGLHSVYYLLYSIQSASTYDGSYSNLRQLLDRKIVHFARLPASVESRPMDTLVNNILSLMYYFLYEHTQLQNYERHCQEALTNFTERLVTFDPELDEKFLFQLSSVCVMMVWRLQVTNSVHTSAAVGFAISVFCQLVNHLTTILEQHSHVKLCSSEGVALSPSPMPSDVDQISVTSVSGSRIREVETDEFDAKQSSQEDGDKNDFTAPKRRKRRRRGRGISDSESEGSDYGTPDFIYTDEEELENSEASDNDWEINSEDEEMNFNGSIPEEDCKFKSSRAFDSSSSNGNSDASVTKTAPELEINGLDNSAAIGAVKTENYKQKFMIPVEDLMKCRSQVEASLVALSPFLRWIQASPVIKDALAANVEKAFLEKLCSTLNLLISQNWPSLLDDLSISEELKSDWKTLCEEPVNEKSIFKWELEEDRSALGIPHFQDFLKDLRIQSVNLNDALVIRIGRMVAFGSWLVSTENFSILYSAEELNYFVPNPQTLKAYLLQSKLKRLRARLGNGTSDELDKLTKAYKDMKISNETMEKASRRNRDDREPRRNRRRRGGGGGAGRRSGGVSTSDPVYAVIDLEALIKRFYDVKRVAANKKFIVVIPHSAWKTLDMLKDSEEEDAKNARIAFRWLEGAIKRKHPGLILQKDQQKMEINFPYPKDPIDVDAWDYFDMMECCNYITNTWLKNKPRSNEVIWGDVRDKCRVFFLTGREDLLNTRIPRSFDPVKIARNVGIFVDYIVPYPGLGRGKKWKSVAKTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRG6</accession>
    <name>A0A1D2MRG6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000649">
        <property type="protein sequence ID" value="ODM95586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRG6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="150" mass="16169" checksum="AC592123C41B0B39" modified="2016-11-30" version="1" fragment="single">MLEQVRSAPATSGLEISSGSSSSPSSSSSSASPSSLSQSPSAGMIMSSGEEGEDGIYHFASVAVGTGCLVAVVLLAAVFLRCYSNWKSSRYHRQLDDEETSSTKANIRISHSLPDLSQDMAKHEYIQEVKEKKLSKRKGKWVKQTPNQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRZ2</accession>
    <name>A0A1D2MRZ2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_11117</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000652">
        <property type="protein sequence ID" value="ODM95574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRZ2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRZ2"/>
    <dbReference type="OMA" id="ELMEWLN"/>
    <dbReference type="OrthoDB" id="17644at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="622" mass="71371" checksum="85064FBE0E385041" modified="2016-11-30" version="1">MVLKSHNFAFDFSGSQVVVTKPNSSELGQLALKHFADEPYMRNFIVSSAEVFVLAQKQFKSCYPDPVPQTTITALSQMYRGIILELVQNLKDVGDLETAALYSNLDFVWNFCEIIFLSSNPDLPVLPYLIDWVRINFDQSSKILPEVQQELPDLGQQCIDKVWKLIYTHVFHGRTREAAKLLPFVNPRPGNSHSNGVGTSASLKNKIEFMTELLEKKPRYNPRTGSFTDFESSWASWREECVNRLEQRVFYGNEQLTFICNVLCGNDEGFSEARTKNLLTWYEYLVMLINYRFPIIRPSALKGYARKVVSDFGLGDSLEPRDIILFHAMEYDIVNVLKEIQAVWNNPWYSTHFVDLIYAGGKFSEVTDVRIDYSSVPPLRTHFIIDYGTTIMEHKPIWQIGVPYFEALEEPLRKHLIGKCIERINPKTEMEAQKLVQIAGQFNLSSELSGICRKVAVDKLKCGQMQNALLWAIKAGDSSLTTHIVDQILFEGDCKIEASLLESLRNAIPCSDRLVFLSGFCDFRKLMDKKDYANAVGKLCQLIKEDMIPKRINHKIIQHLVTLHDKNVKFRANETTILMEFVHLRVGINKIEPADFTRLNMLLVCNRANEILTMFNNKTFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTF1</accession>
    <name>A0A1D2MTF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000567">
        <property type="protein sequence ID" value="ODM96181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTF1"/>
    <dbReference type="OrthoDB" id="6368363at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="112" mass="12954" checksum="3BDC4DDC2C55DE97" modified="2016-11-30" version="1">MTPVPFLPMIFRRHPRKRNERISIAVYAAIAVILAQLSLTIQGIDNLEGEAGFRMVSLKWMFPPEGPSQRSPISFQVKFCELHSWGLNRCRYQFIIHSSEKKPETFSVGWAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTK0</accession>
    <name>A0A1D2MTK0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Collagen alpha-1(XV) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000592">
        <property type="protein sequence ID" value="ODM96025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTK0"/>
    <dbReference type="STRING" id="48709.A0A1D2MTK0"/>
    <dbReference type="OrthoDB" id="10060752at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="243" mass="26928" checksum="2362A60CD1E4A4C7" modified="2016-11-30" version="1">MHCVIGDNVTLFLNCREHSSKLAMRNPKELSFDPASTLYIGQAGPILKGNFQGAIQELKLYGNHMVSEVQCEDAFSSFGSTEGSSSDFTNELADFYDYPTYEDEEEINMDELGSGGLPPPPPRPPPAPTDDGHPFFDEENGSQGGKDKTNKDTSVFTPFVPTTKKLPNHRSGSTWYEDGLDSETAICQCNHTEILMKLPETLRGLPGPKGEQGRIKYFSFLSNLRGNWPRDSRAARNAARKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTT9</accession>
    <name>A0A1D2MTT9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000538">
        <property type="protein sequence ID" value="ODM96463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTT9"/>
    <dbReference type="OMA" id="TECMERY"/>
    <dbReference type="OrthoDB" id="8287884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="28782" checksum="854199C7429B7CED" modified="2016-11-30" version="1">MALTALFPVLQQNMYHQCPVRSDVCFSSPLMKMGQASTALALLLSSGSMTPTKAMFSNISVAPSSSWYFSLSPFESILLGLLVLKLMLLRYLTILPIDINNLANKDYFDFGKKRRKRDTHGLDESKIRKEKERLAEIMFTVIRRLDMQDCFLRMLCELQAHSIQGKTLPREVKLTLSALSKSGWKRQQEPKIDLGPDFIADRPILSVFEEAVQVGWDAKGKNSTECMERYFICPLSTEDIFSHFDTVKVVDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTY4</accession>
    <name>A0A1D2MTY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000558">
        <property type="protein sequence ID" value="ODM96264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTY4"/>
    <dbReference type="STRING" id="48709.A0A1D2MTY4"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="209" mass="23254" checksum="C554F5C5368A226F" modified="2016-11-30" version="1">MFKRDIIRTYNTLEARLAWHGKCSAGREFTVLESIRRAVAGLAGISLLRVTDLALTEWPSGTSAFWFSLRQIVNFQELSRNNNTSHSTIVFPLADAYRILRDVISRHDVTLRVDLSPNEHMLVGIQRGSLISIPRALHPIFMRNINSKSLSVIKASYTSGAVAGLGLAMAVLGLAIGLLLGFVLWNGSTRMRYWRSPWSNSPIPYGLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUD3</accession>
    <name>A0A1D2MUD3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_09990</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="LJIJ01000511">
        <property type="protein sequence ID" value="ODM96697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUD3"/>
    <dbReference type="STRING" id="48709.A0A1D2MUD3"/>
    <dbReference type="OMA" id="VIHNVYS"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056452">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 3-BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23546">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPO_IA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Topo IA-type catalytic" evidence="9">
        <location>
            <begin position="169"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="806"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="821"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM96697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="845" mass="94887" checksum="43ACF99B70435DE4" modified="2016-11-30" version="1">MGKVVLMVAEKPSVAELIAQKLNSRNLRSRKALNGIPVHEWDGNFRNVGSVMFRMTAVTGHVHGMDFPSKYNSWDKVDPAELFECPVEKTEANEKQRVPQMLKAEGRNADYLVLWLDCDKEGENICFEISDILQDTMTLIPGQTLFRARFSALTGPDLEKAIDNLTVPNENESKSVDARQELDLRIGCCFTRFQTRAFHGKYGGLDSTLVSYGPCQTPTLGFCVKRHDKIQSFKPEKFWSINVTVGLDGDKQVSLEWRRKRLFDKEAVEYFLSTMKDAKVAIVSSVKKKECVKKRPVGLNTVEMLRLASSKLGMSPQHTMQVAERLYTQGYISYPRTESTHYPANFDYKSDLGKFSKHDEWSSLISWNSIVSPLKGHDAGDHHPITPLVATHSGTFHDSDAARLYGFVVKYFIATFTEDCTYLETNIDFRIQNESFGFQGKEIIKPGFTKAYPFSVISNSDQIPEVKVNTSCPVLEKKLYESETKPPDYLTESELISLMEQHGIGTDASIPVHINNICQRNYVQLVPGRKLVPTELGIILVHGYLRIDPELVLPTMRSEVEKQLDLIARGEAQLSPVVDHALDIFKAKFLFFVKNITSMDELFEVSFSKFADGGKPFARCGKCRRYMKLVSLNVSRLHCATCTDTYNVPQGGILRAFNDIRCPLDDFELIQWNGGSKDKSYTFCPYCVNNPPFPGMRKGNACNMCLHPTCPYGFSNKGICACEECEDGVLVLDPASGPKHKVSCNKCDVFISIFEGSRRVTVLDEETCESCESALVLVDLPKRANEGEKKGCIFCTEEFEPFVEKHRVMDQKRGGGGRGGRGGRGRGRGRGRGRGRGRSRGRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUE8</accession>
    <name>A0A1D2MUE8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Protein toll</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_10152</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Toll-like receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000530">
        <property type="protein sequence ID" value="ODM96531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUE8"/>
    <dbReference type="STRING" id="48709.A0A1D2MUE8"/>
    <dbReference type="OMA" id="WSCRCKF"/>
    <dbReference type="OrthoDB" id="2015831at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001438">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF161">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="676"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="TIR" evidence="12">
        <location>
            <begin position="727"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="893"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="939"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1004"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1075"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="946"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1035"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1047"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1078"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1144"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1196"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1210"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="1231"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1250"/>
            <end position="1260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM96531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1260" mass="140232" checksum="26170E3E52FDDAD8" modified="2016-11-30" version="1">MVVSTLNLKLNQLVALPPKVFHPCKGIRELDLHNNSLTALSPMLLNGLEHLQVLDLSMNSLASQYIASEIFNSCVRLVILNLRSNQFTHISNTTFTNLYSLQILDISENLISSIDENTFAPMSNLHSLHLGRNRLVSIDSNMLNGLFVLSKLSLDYNQISVIRPDAMKNCTSLADLSLIGNRIGESNGEVPHALRSLANLRSIDLGENSISQFHSESFYGNSNLIGLRLVENRISELGSDLCQYNKNLRVLNLAKNRIPSGKISSRAFHSCGNLRVLRLDENLLDEINFADTLPSLLWLNVSQNALKVLDYGLLPKKLEWLDIRYNELESLVGSHGGIRAMDASYNRLTNLSHHSIPTSIEILRVNNNRLNRISRDTFLGLSSLRRVEMISNQLENIPLNALRISPNGNPTKPLPEFFFGGNALLCDCHMEYLAPSRLKQLNFKTVCPSNCTCYRDSEWLFNVVNCANSGHTSIPPLPMDTTEVYIDSNNIKVLKSHSFIGRKNTKKLFLNSSGIEQISNKSFNGLQSLEILHLEFNRIKILHGYEFDQLSRLRELYLQSNLISAISNQTFLGLKSLEVLRIDGNRLAVFQVWQLSLNPYLVEAYISNPFSCECDYLHQIYLWVTDNSRKVVDLRHLQCFWNTTHKPGPHLIDYNQTCSSWAIMQMKNGFDFTSPLPLALAFVSFITLFILVVALVILCRENFSLWLFTKFNGLRMCSAGADFEDDKSYDSYLIYSQKDEEFVAQRVADMLETNDNYRLCLHYRDLICETGDLKDMMIGALENSKSVLIILSRNFLQGEWSSGEYRSAFHAVLKKSQRGGGGMNMGGGGGKTPPKKILIVFIEDIPKVEISPDIRSWVRHNKIQVIKWNIHSPDYNKNRKFWNKLKFSLPDPSSHYHSNITSNTTTTSASSGESNGGIMATLKYSTAMQAESQLHHVPHSHIGQHPNHHHHPHHHHQTHPHHHQQIIVDESGRFTTITTSATNTLNSVKYWPYGATNFVALPPKYQQGSHHGSVGGSHPPSMHSPGSPHSLHYHPPLPISNPPKSPPSSQSTDSTTTTMADEAPSLLSQLTMASFNRSNNSPSASSATKSPVPVPKSSYSSRNTLVNNPISNSNSTSNNIVNGGESYLDGEHVYSTLDPPSPQPTQQSMSLSQNILGNGSSGGAPNFLNNIHLPNGYTYQPQSSLNQHQQNHHHFAPLSSPSGAAAPGNKHGHGGHHHQVMSSFVGNGAANNGGVGTGGKQQGFKQKVSDGNNPVQTYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV50</accession>
    <name>A0A1D2MV50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="32">Protocadherin-like wing polarity protein stan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="32" type="ORF">Ocin01_09825</name>
    </gene>
    <organism evidence="32 33">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="32 33" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="32">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Apical cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="32">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000496">
        <property type="protein sequence ID" value="ODM96856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MV50"/>
    <dbReference type="OMA" id="TEVYTVI"/>
    <dbReference type="OrthoDB" id="26203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016339">
        <property type="term" value="P:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042067">
        <property type="term" value="P:establishment of ommatidial planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022603">
        <property type="term" value="P:regulation of anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048638">
        <property type="term" value="P:regulation of developmental growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051239">
        <property type="term" value="P:regulation of multicellular organismal process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035159">
        <property type="term" value="P:regulation of tube length, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="CDD" id="cd00053">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000185">
        <property type="entry name" value="basement membrane-specific heparan sulfate proteoglycan core protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000013">
        <property type="entry name" value="Cadherin EGF LAG seven-pass G-type receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1240.10:FF:000021">
        <property type="entry name" value="Cadherin EGF LAG seven-pass G-type receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000010">
        <property type="entry name" value="Cadherin EGF LAG seven-pass G-type receptor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000029">
        <property type="entry name" value="Cadherin EGF LAG seven-pass G-type receptor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000020">
        <property type="entry name" value="Dachsous cadherin-related 1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000058">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000082">
        <property type="entry name" value="Laminin subunit alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000005">
        <property type="entry name" value="Protocadherin 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000134">
        <property type="entry name" value="protocadherin Fat 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000249">
        <property type="entry name" value="Starry night"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032471">
        <property type="entry name" value="AGRL2-4_GAIN_subdom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056286">
        <property type="entry name" value="Cadherin_CELSR1-3_9th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057244">
        <property type="entry name" value="GAIN_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046338">
        <property type="entry name" value="GAIN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001879">
        <property type="entry name" value="GPCR_2_extracellular_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000203">
        <property type="entry name" value="GPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026">
        <property type="entry name" value="FAT ATYPICAL CADHERIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026:SF51">
        <property type="entry name" value="PROTOCADHERIN-LIKE WING POLARITY PROTEIN STAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23592">
        <property type="entry name" value="Cadherin_CELSR2_9th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16489">
        <property type="entry name" value="GAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00303">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00008">
        <property type="entry name" value="HormR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50227">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50221">
        <property type="entry name" value="GAIN_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 20" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="15 21" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 21" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="13" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="19 22" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="14 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="33" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="18" id="KW-0807">Transducer</keyword>
    <keyword evidence="7 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 24" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="2875"/>
            <end position="2893"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="2905"/>
            <end position="2925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="2931"/>
            <end position="2951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="2972"/>
            <end position="2992"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="3012"/>
            <end position="3035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="3055"/>
            <end position="3076"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="3082"/>
            <end position="3105"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="461"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="566"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="675"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="782"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="907"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="1010"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="1195"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="1276"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="31">
        <location>
            <begin position="1411"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="26">
        <location>
            <begin position="1762"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="25">
        <location>
            <begin position="1842"/>
            <end position="2040"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="26">
        <location>
            <begin position="2043"/>
            <end position="2079"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="25">
        <location>
            <begin position="2085"/>
            <end position="2241"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="26">
        <location>
            <begin position="2279"/>
            <end position="2318"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="27">
        <location>
            <begin position="2383"/>
            <end position="2430"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 1" evidence="29">
        <location>
            <begin position="2415"/>
            <end position="2488"/>
        </location>
    </feature>
    <feature type="domain" description="GAIN-B" evidence="28">
        <location>
            <begin position="2670"/>
            <end position="2864"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="30">
        <location>
            <begin position="2876"/>
            <end position="3106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="2794"/>
            <end position="2816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="3168"/>
            <end position="3203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="3168"/>
            <end position="3181"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="21">
        <location>
            <begin position="1788"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="21">
        <location>
            <begin position="2069"/>
            <end position="2078"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="22">
        <location>
            <begin position="2383"/>
            <end position="2395"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="22">
        <location>
            <begin position="2385"/>
            <end position="2402"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="22">
        <location>
            <begin position="2404"/>
            <end position="2413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS50221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS50227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="31">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="EMBL" id="ODM96856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="33">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="3203" mass="358513" checksum="22338773E01C6982" modified="2016-11-30" version="1">MKKYWNNYIMCVVLNRKMYFHHQHHLPKKKRQRLKLHHSGSTISSSNSPSLNRNKVLMSFSVYSVCFVLLFLLSTATSFVIISDQDTPEGWILFDAHVPITTTTTSSRNYRDEVYSHHNQQHHNIQQRHYGNIPSGFHYQYRISHHKTQPWIHRIVKLDKDGLLQLKKSISNCQFTAGLYPSTFLVYIDIVARYKSTLPEDDHGDWDGGGENSRKISRRDLAQKDHDEQDEVGDELASNYDYISFPVTIILKRSSECHNSNNNNNLQGKSSSTTTSFSSPFSVEGWKSSWNANNNNHDAPSSNKINNVEEDVSTHVARSVDDIYVSLPLDQDNHCHHTNERIANVFHFLPASVRAQCSVKAEVVTGFEHTFGIQQGTLDIVLLRDWCLFDVYQTIQLLLRLNCTGMGGSGGNLRGLPEKVMAWDQMVHLILHQPGANNPSLDHHPIHRIRREMRNQAPYFDQPLYIAAVPEEQPAGITVTTIGATDPENQPLTYSMTSLLDARSQQFFSLDSKSGVVQTTSRLDRERMDVHYFRIVATDSGVPPRTGTGTLQINVLDSNDHDPNFEQSQYSVSIREGLSVGSTVLSVRATDQDADKNGELFYSILNPHDIDDTFRIESSSGVISTKLTLDREKRDEYTLLVQATDLAQSQAERKTATATVRIEILDDNDNYPKWTQRSYNVSVPENLDATNYPVISTVSATDADEGVNAALRYSIIGGNNQNHFSIDSLTGEVSLIKTLDYEATRSFRLNIRAIDNGNPTRSNNTQLVINVIDENDNAPKFYSQIFQETVQENLPISSSVLRIQAFDPDDGPNAKIYYRINYQENPEKFPFDIEAESGWIKTVRELDREEQSRYDFDVIAADSGDIPLSSTASVVITVQDQNDNVIIQHETFSFTPKNTQQKDPHFSPKLYESQVSEEDSPGTPVVTVKATDPDENSRITYEITEGNLRNRFSISTQNGVGLITIAQPLDFKSERKFVLTVKATDSGGRTDVATVYVDVIDANTFAPVFQNTPYSVKIFEDVPIGTTVLAVNAVDQDSGINAQIVYTLLDEGDGGGSESDNAAFMIDSNSGAITTTKLLDREKVPGYILTVVARDRGIPPMSDTTDVEIVINDVNDYLPVFEKDFYQAKVDEDVPVGTSILQVQASPFRNNILHFMVKCPLTKNIIGVHKQRGNKDDLLQKPAFYTVHVMLLFQDGDQGKNSIVRYSFSTFSDGDGTFTVDPASGVVRTVKPLDREQVSRYDLMVLATDQGSPQLTGRTNVTITILDKNDSPPMFESDRIRFFIPENSPLGSTVGKLTAWDPDEGVNAQVIYSIVGGVDANSFTLVSHPSPTVNGQSGGSGSADILTRIELDYESSRKKYDIIVRAASPPLRNDVHVEIHITDVNDNAPMIQPQFFVTLNNYKDHFPVGPIGRVPAVDADISDKLQYTILTGNKANLVYLNESTGMITLSPYLDTNVPLMAKMDVLVSDGLNEARSEMILQTHYITDELLFNSVTIQLAEMTTEAFLSPLFHHFQQAVALILNSPKENIVIFSVQSSKKCSTHPVFTFSSSYSLQSFILLVPFIHSFFLSALLLHFSSFGNANLFQEEVEGNHGILNVSLSARKPNTLTEEYFSPHYIKERVFLNRITLSKLATVEYWVELVQYNFKNAPYYFFTLGIVHPYFTHETLHMQYTMLRRVNIDGYQVTHRSLGKHVLPFSDDLCLREPCLNFEECLVVLKFRNVSNFVPTDTMLFRSVYPWQTFACRCPPGYTGLREHYLCDAEINLCFSSPCRNGGTCFRRERGYSCVCPSGFTGPSCEIQLELDTCQPNICGRGSTCTPRVRGGFLCQNCSRNEYVNSLCELTARSFSRGAFLTFPGLKDRYRTHIKLSFATQQKNGMLLYNGRYNERFDFIALEVLNSTVRFSFSLGSSNLTYVDTGKSMSDGLWHTVEVSYSNQTATVSVDDCDIIMSLENPDEFPPSSSCAGKGTLWLEPRCRSLTESCQRFLDLTGPLYIGGLPAPNGPTQIQTHDFVGCIKNVYINHKFLDLNNYVMEHGTSAGCPEKKNFCATHPCKNGGKCSDGWGTYYCQCPDGFGQKDCSEDAKPVWSLRDENSYLVFIPQLRPIGFPWYTSLSVRTVKPTGTLMSVKVSSNETIKLTLDNGVIHYFYEDQAIPVSLPRIHDGHWHHIEAKWMTAEIWFSLDYGQFETTAPFEEKVKNLHISQVTVGHPSSSVTACVQDVRVGSAKNYLRKTTHEKNVNEGCSLATACVGAVCPPRSTCVEQGGRPKCQCDAGYVGVHCIPICDLKPCKNNGSCVLDLTTPRGYHCKCDERYYRGKNCEKVMELTCPTTWWGWPVCGPCSCPADKNYSPECNKTTGQCKCKASPKQCYHTSDYHYEKDGVCKDCQCYTVGSLSKNCDLQTGRCQCRAGVLGNRCDTCASAFAEVTLNGCELVRDGCPRALDGEIWWPRAKFSTNSVHDCPSRSIGLATRECRSPQGWAEADLFNCTSTRFVPILNIVNQLDSRDLSLSPLLSTKLAADLSKALNDTTAGGSRLFGNDISISQRLITHLIQHETKQKGLNLSHRQDKNFVKNLITATGRITSKEYSSEWARLKRNYGAGADNILRLMERYLAHLVDNQEDTYTKPFELITSNLVMGLDTVELTWDNDGRKNFEDLTIESSYDLYEVTTTTKRAVRFPKYDNVVMDPRRYTTNAKIIIPLDILGLHDEKDMAGNAVVGYLEYYSLWDVLPKQFKNDVDRRFNSQQVAAQPIISLSVLASRLGLVSGKQSSPIRIKFEIFGRYIDSSNPQCVIWDDGSSEEPTTTSVPGKTVIPPTTTTASSQGWTTLPCITQVEENYLPKMGNVMTVNCTCWHLSTFAVLLEDSEIQDVPRPSIVEDIVTYVAFSMTLLLIFLALYQPPLPTLHKHLLLSIFGAVLFYFVAIKLRMILVQNDAICRVIAIGLHVTWLATFAWLLSSAIHLRRMFTEVRDVNHGSALFYFALGYAFPLLCVALSLGVRAHHYGNKFFCWLSLYEGIVWGMVGPILICVVATLATFLVAVRAAFTLKDQVVDSGNMRTLLWMDLTLLPICGMCWALCLLGANERNPVWQYAIAIAVSVLGLYIALGYCVLNQRVKESLYIRAGGLFQSRDNAQAANVSRSALAYRNEFGGTSGREDFRRDIFRGVHSLGVSTASTTSRSTTKTSSSPYRSDGFNGYGSTLPHLHHRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW92</accession>
    <name>A0A1D2MW92_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000454">
        <property type="protein sequence ID" value="ODM97329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW92"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052808">
        <property type="entry name" value="GPCR_Mth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="252" mass="28464" checksum="9D4532CC6534F6AD" modified="2016-11-30" version="1" fragment="single">MNVSNICIDGAVNIPGHFDATNKQQVFSGDELDTIIVECGPALAEEETDHPTLLYGIALFISSLFLVAIIVVYGLLWDKQNVHGLTMLGYVITMLGYYMALLATFIYLYAYPNPNYVNETEIFSSFCGIIAYWNKVKEQSQIHHLPYFHRRSSIHYCGNCSITGSSYGDELEENIVLPRYGWNKCFMDLEYAALPYYFAPAGSLLILNCILYFTTIFHIHKLQESTKFASATSSSSQVQKQRAKTAFHNVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWA8</accession>
    <name>A0A1D2MWA8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oxygen-dependent choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09588</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000474">
        <property type="protein sequence ID" value="ODM97094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWA8"/>
    <dbReference type="STRING" id="48709.A0A1D2MWA8"/>
    <dbReference type="OMA" id="HNDPSPI"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="643" mass="71170" checksum="E89C04D55451ECED" modified="2016-11-30" version="1">MSSVEDVPGFAPIINTVLQPLPRFMVNYFLGSAPYLILTLATLMSYNDFFRASNQIPSLLFGPREPVETFDFIVVGGGSSGAVVASRLAKNFKVLLLEAGGDPHPTSYIPAFACFLYNKPQVDWGYKTRPLNGSGFGSTSSGGCLNYPRSKSLGGSTNVNDMIYMRGNPSDYDNWAIVTTDRRWSYENVRKYYQKMEDYHGHYSSDEDNDHGVGGPMHIEKAGYTPSIQYWMDAGSELGLKTGSDPNNQQGEGVFQLDVMAKRGVRYGTYRAYLEDNLRFRNRNNNNLVVHRYSIVTQIHFDENKTATGVTYFRHAIKQQARASKEIILTAGAINTPKLLLLSGIGPKEELESVGIEQIADLPVGKNNLQDHVSTLVGPFLLNKSESFLASRDVTTIAAASYLSQGIGPFSVTNFVSAAGLFSTSSALPLWPNILYTMMAAGTDRILQNHLMYQFSLNRQNLESFLQNNLGKDSNYVVVTLGKPRSRGSVRIPSFDPWHEPHIDLNYYSDEGDRDMNDMIEGIKMAVNLYENTTSFQKLGAHLAPEQYPGCEQHEMRSDAYWDCLIRTVTVTLSNPCCTAPMGLKDSPQAVVDSELRVIGVKGLRIADASVMPEITNAHLNAVPIMIGEVASDLIIHDHPGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWJ5</accession>
    <name>A0A1D2MWJ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000465">
        <property type="protein sequence ID" value="ODM97184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWJ5"/>
    <dbReference type="STRING" id="48709.A0A1D2MWJ5"/>
    <dbReference type="OrthoDB" id="5976067at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051254">
        <property type="entry name" value="PPP1R15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16489">
        <property type="entry name" value="GH11727P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16489:SF12">
        <property type="entry name" value="GH11727P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="576" mass="63422" checksum="BEB4DA8A225722AA" modified="2016-11-30" version="1">MSKTERRKLFQPIPLSSILDPSHQTPFSKLEQFQFDLDLSNVHSHRPEVEQISLWRKLQTTLINAMSNLVVISQPVFATSMGKSTANSASTMSLIPWKPNKSSELSEVINLSDGSGSPLLSPSKQDSRQQQSLYHSVRSGLECLRYFATHPLHEEKATPVHSCKQNINSSYDFSYSDSSSRVSFEPNSGYLGSSAILFPAPFPFFVASEHQYYSSSWCPAAPQVPAPNLFSLAMSGFLLASPPYLNAFYENSCLFSPIHNIKGSPAAHKPSRTMNGVGSEFEIIIHATSHQSSQEPGKGLSSHTSASASAKNTSSMSEGGGGGGAGGCIRVANWRSNNNEDNCPFQSVSVCSSSSSKGGTVTFSCASATVTSSSPRTMAMACPRSANRRLKTESESSVDSFVEFSASVESTDSFCIVFESAGGCIDEEYLLEFDRDDDEWEDDDDEEEESEDEEDQIFDYAAETDGEIFQTEIDDGNELQGLAEHDQTDGASCSATCSKKRKSKKVSFDEENLVSVIEFEDDAESRRARETYWEVFARDRARFQDRIFRTGDILEPILLGAHRTKVFSCRFKEPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWT5</accession>
    <name>A0A1D2MWT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000436">
        <property type="protein sequence ID" value="ODM97517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWT5"/>
    <dbReference type="OMA" id="IMAWENR"/>
    <dbReference type="OrthoDB" id="5519333at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027861">
        <property type="entry name" value="TMEM249"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35442:SF1">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT TMEM249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35442">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15158">
        <property type="entry name" value="TMEM249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="289" mass="33786" checksum="75BE95D98AB6DD34" modified="2016-11-30" version="1">MFKEDTLCTLLKNWWNYKPEDELYYRLQDNPYWPFKMISDGYFYVVVQSDRAAYGMWTLIATVGCYAVCTIILGFYSIPQSFFLISLLLSLWTLRGRIAWRELIISRRGRGSYMLRVLSNQEKLIQHELRNIYIRLAKKDDSSGDPYFWLNLSGYELDDYRITRMTKAESALRIMGMRLAYRLGVNFFDWKDESEEHLVFHYKTHSKLTFHPHQLTYYKTKDDTAGKDSIAVDDTKSTSETRQQAFLVVPPRKARTATSGDNQSSKKQKGQSVDDKKKVNISDGSDTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWZ6</accession>
    <name>A0A1D2MWZ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein unc-13 B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09119</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000431">
        <property type="protein sequence ID" value="ODM97566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWZ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MWZ6"/>
    <dbReference type="OMA" id="TTHVTQM"/>
    <dbReference type="OrthoDB" id="10053234at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031594">
        <property type="term" value="C:neuromuscular junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098831">
        <property type="term" value="C:presynaptic active zone cytoplasmic component"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042734">
        <property type="term" value="C:presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030672">
        <property type="term" value="C:synaptic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043195">
        <property type="term" value="C:terminal bouton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019992">
        <property type="term" value="F:diacylglycerol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017075">
        <property type="term" value="F:syntaxin-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061789">
        <property type="term" value="P:dense core granule priming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099525">
        <property type="term" value="P:presynaptic dense core vesicle exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035249">
        <property type="term" value="P:synaptic transmission, glutamatergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016081">
        <property type="term" value="P:synaptic vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016082">
        <property type="term" value="P:synaptic vesicle priming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04027">
        <property type="entry name" value="C2B_Munc13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08395">
        <property type="entry name" value="C2C_Munc13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.50:FF:000001">
        <property type="entry name" value="Protein unc-13 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000002">
        <property type="entry name" value="Protein unc-13 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000014">
        <property type="entry name" value="protein unc-13 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000001">
        <property type="entry name" value="Protein unc-13 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010439">
        <property type="entry name" value="MUN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014770">
        <property type="entry name" value="Munc13_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027080">
        <property type="entry name" value="Unc-13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037302">
        <property type="entry name" value="Unc-13_C2B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10480">
        <property type="entry name" value="PROTEIN UNC-13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10480:SF12">
        <property type="entry name" value="UNC-13, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06292">
        <property type="entry name" value="MUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01145">
        <property type="entry name" value="DUF1041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51258">
        <property type="entry name" value="MHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="8">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="126"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="MHD1" evidence="9">
        <location>
            <begin position="558"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="MHD2" evidence="10">
        <location>
            <begin position="813"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="1047"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1017"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1020"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1220" mass="138820" checksum="47178D8822580E4A" modified="2016-11-30" version="1">MHVYKKTLQALIYPISSTTPHNFVLWTATSPTYCYECEGLLWGIARQGVRCTECGVKCHEKCKDLLNADCLQRAAEKSCKHGAEDKANSIITAMKEIMKQRERQKPEIFELIRTTFTVDPDTHIDNLEQAEGSVLEGTSKWSCKIAITVICAQGLIAKDKSGTSDPYVTVQVGKTKKRTRTMPQELNPVWNEKFYFECHNSSDRIKVRVWDEDNDLKSKLRQKLTRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHHLCEVQVGMMNLPSSKGDDAWKVYFEDPGQEIVDEFAMRYGIESIYQAMTHFHCLSTKYLCNSVPAVMSTLLANINAYYAHTTASSAVSASDRFAASNFGKEKFVKLLDQLHNSLRIDLSMYRNNFPASSQEKLMDLKSTVDLLTSITFFRMKVQELSSPPRASTVVKDCVKACLRSTYQFLFENCYELYSREFQVDPNEPKREPDDNGPRLDSVDFWHKLIALIVSVIEEDKNSYAPVLNQFPQELNIGQLSAATMWSLFAVDMKYALEEHEQHRLCKSSAYMNLHFKVKWLYNNYVKEVPPYKGSVPEYPAWFEPFVMQWLNENDDVSLEYLHGAFKRDKKDGFQKSSEHALFSVSVVDVFTQLTQCFDVVSKLECPDPDIWKRYMKRFAKTIVKVLLAYADIVKQEFPTHTKDQDERVACILMNDIMQLRVQLEKLFEAMGGEKLEEDAATILHDLQNSLNAVMDDLAIQFSLSLEIRITGSVKELGDLLLAVKGQGNFNLSQPAQRNQVAAEADEVLRPLMDLLDGSLSMYAEICEKTVLKRLLKELWKIVMRTLEKQVVLPPMTDKSMLLKNITSNAKKMMEIPNANATMENMGQLFKKNMAKHDVKSALSGVMVSGVMELEKNLSPKQCAVLDVALDTIKQYFHAGGNGLKKSFLEKSSELQSLRYALSLYTQTTDALIKTFVTTQLTQVPLNDKKTIELRALSFDRDDEFSGEPGLEEVLKAKKPKEPLKKGSKDIPSMDEGSVGECSIQVDLFTHPGTGEHKITVKVVAANELKWPSTGFRPFVEVNLIGPHLSDKKRKQATKSKSGTWSPKYNETFHFIVGNEEHLDCYELHICVKDYCFAREDRLVGVAVMQLRDIMEQGSCACWLALGKRIQMDETGWTILRILAQRNNDEVAKEFVKLKSDVRPEDNLISSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZA0</accession>
    <name>A0A1D2MZA0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000368">
        <property type="protein sequence ID" value="ODM98271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZA0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="358" mass="41128" checksum="AF71900CCC3FB994" modified="2016-11-30" version="1">MEFCDFTGDSDFEQFMPTRNASQDSMKSNDDNDNLDSTPGYCYCPPDESDLQILRDKQLRGRGYRYKYRKPCNKKTSVNNDSEYSCFPTETCCGMETTVSEQFPPRYSKIKATNPFAFLMTGGRTAKSTMRKATAVINPNECCNHDEPSGSRKFILQFDKQNAATISDRSDSCYVAEKDRCTEFWEFVNGTPELEKIIKDGTFFHNVPPKEVDKSGHPLKEVELQSLFKAIRKSKDISKYSPEMEALRQRNIKVREEEKKRREKLRERIKIVQEKSGQKYRMGQLNYDDGSKKPCGHLADCSNPSPGEVLEEMEYFDELSSNPVQVGCKFRKRRQSCKEIFMPFGDDAGEGAYSEGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N082</accession>
    <name>A0A1D2N082_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000335">
        <property type="protein sequence ID" value="ODM98696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N082"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="223" mass="25200" checksum="E96DC7E85F2C2FD0" modified="2016-11-30" version="1">MSILPWTPESFLSSFVIQPSRYSNCYVKISLTRKNVNIKSSHIIILIITLQHPQIMYTLESRNWRTYFGDTLCIGLNANSSTSPTLRFILNPDKPAPATPNNEPITAAPKILKNICQLWRKSTIFNTIFSSYFNLILVTCCTSDCDCCSPTKHTRHTSSCKSIIVVTQLWERTDKLPISGAASPPVRPSTAPPPKVASPTRAYRFIFRFLNRFLLSFDSSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0D2</accession>
    <name>A0A1D2N0D2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein prune</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPase class C family. Prune subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000330">
        <property type="protein sequence ID" value="ODM98732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0D2"/>
    <dbReference type="STRING" id="48709.A0A1D2N0D2"/>
    <dbReference type="OMA" id="QNSCAEP"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="2">
        <location>
            <begin position="129"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="509" mass="56240" checksum="6BBD15BAB702BDB9" modified="2016-11-30" version="1" fragment="single">DEIDLIALQSTGRMKLTLVDHNVLAQGDAFLQNSIVQVIDHHKRERQFDRRDIIEPVGSCCTLVAEMVLGLFDKDPVICALLYGTILLDTINLNPSAQKATPKDVKLTSELEDTLARALGSPLKRDDVYEPINKARTDISQLSPDQLLRKDCKLLKSPEITIAVPAVPLLSQKFLELPAAVEALRNSLRLNRCTAIVLMGWEVDMEGTMRRDVTIFSDGIHKAKQVCTPMENCGELQLQLVKSSTESQSVYWTYNQKNAALSRKFILPFLATHFETKAQNHLDVDALAGVEILIPNGEMSPNKIGTCPVPSISYSSVQNLGIGDPISHCGSNQSSAYNSCPYTPQNSCAEPEDGYPSEQYFLPSFNSREMIEKIELKRHKLRGYDKSEDQLNPGACSSYPYTPKNSFVESNMEALFEQQRSNNGGVLHEIDSEVLLRKLLEKRKDNLNASPTAHSISNTSSKSQSLTKLNVVDEAAAGGDISSQLSPTYQVRLTENYVSSMESSGGDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0L5</accession>
    <name>A0A1D2N0L5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_07857</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000319">
        <property type="protein sequence ID" value="ODM98826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0L5"/>
    <dbReference type="STRING" id="48709.A0A1D2N0L5"/>
    <dbReference type="OMA" id="ATPPFWA"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF98">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="86"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="534" mass="59588" checksum="9F3060956C0C355B" modified="2016-11-30" version="1" fragment="single">MYVKQTTARSDSLAQPDLFSSESHFGAIVPNKQPAELLPGEPIHHESVHGREGEGHESTEHGGIKVIKVDFEEVETPFIIALWIFCASLAKIGFHMAPKLSHIFPESCLLILVGLVIGLLLNYTQSVHVSPLTPKTFFHFMLPPIILDAGYFMPNRLFFNNLGTILLFAVIGTLWNTFSIGLSLYGLGFTGIFGGDVAEHLTLLPTLLFSALISAVDPVAVLAVFEEIHVNEVLYIVVFGESLLNDAVTVVLYHMFEDYATMGENQIDTMEIVKGIASFPVVALGGTAIGIIWGFLTGFVTRFTNHVRVIEPIFIFVMAYLSYLCAETFHMSGILAVTFCGITMKNYVQANISQKSQCTVKYAMKMLSSSAETIIFMFLGVSTIHDEHNANVWFIIFTILFCTVYRIIGTIVLSALANKFRLHKLGRVDQFVMSYGGLRGAVAFALVLLIKEEAVNKNNELRKMFITTTIAVIYFTVFLQGITIKPLVCWLKVKRAEKRKPTMNERIHERLMDHTMVVLESIVGQTGHYKLRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N130</accession>
    <name>A0A1D2N130_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000305">
        <property type="protein sequence ID" value="ODM98993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N130"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="25756" checksum="8D815A3C6FC4D7BB" modified="2016-11-30" version="1">MSVKDPLQFFVFVTSIASIILLLLSNYVESASFGTTRPEGTGGIQRYENGRKVPEYIQSSILKYCEKCSDSQRKTVEDVLLLLFSLDPDQKTSENSSKFKQKLKKTLMKAQKHKKPTTLNPRDRWPSVPAPEVALQYYNVDNFQQQQVIPFPTTSTTPSGVGSPSTTVSSAPAPAQSVEMPTPPTATYNDWAHLLLLPECLSSSSLQPPTTSELWRVVLLKRGEQRCSLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1I4</accession>
    <name>A0A1D2N1I4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000296">
        <property type="protein sequence ID" value="ODM99153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1I4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="322" mass="37788" checksum="2C7BC4C6815E17D1" modified="2016-11-30" version="1">MPDNNNGMKKRKVISSSHVENEEEYSYQLNSSPMEEDSKKHQKISKAKYKWLRRMTLEVNKFPYSNTKTLGLYSFEVTELEWYYKEIRLLADKVLDILECPVCEDTIKKAVMPGCGCDNPLACCSKCWMEAGSICFNCKRNCTSIPFEPVDEIIRECHLFMKERSPFPFQKDKNIHDSELKRICESYHQFLKQSEMQLMCNYCFGTLENTITINCGNDMRSQVCTGCHELYMECYTYCTDFSAYPTFDRLNREYCHFFSRVLAYCSSNKVQMYTDPYPNMKQPSYFKLRVMKRNGLKSKVFGVFKKAIVVAACAYLVVYFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2V0</accession>
    <name>A0A1D2N2V0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras-related protein Rab-14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000270">
        <property type="protein sequence ID" value="ODM99582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2V0"/>
    <dbReference type="STRING" id="48709.A0A1D2N2V0"/>
    <dbReference type="OMA" id="NWAQTIT"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001728">
        <property type="entry name" value="Ras related protein1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="232" mass="25819" checksum="06CC170BB5FF256A" modified="2016-11-30" version="1">MSGGPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVCGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALIIYDITRRSTYNHLSSWLTDAVILPIQTLETANCVTFNWAQTITGDFSNWKQIRPRWPEGCNLRKAKKFADENGLKFVEASAKTGENVEEAFLETAKKIYESIQDGSLDLNAAESGVQKKPTANGARSLSADNAEGRNPSSCSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2X7</accession>
    <name>A0A1D2N2X7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transient receptor potential cation channel subfamily A member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_07065</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000268">
        <property type="protein sequence ID" value="ODM99618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2X7"/>
    <dbReference type="STRING" id="48709.A0A1D2N2X7"/>
    <dbReference type="OrthoDB" id="1661883at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902495">
        <property type="term" value="C:transmembrane transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052076">
        <property type="entry name" value="TRP_cation_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143:SF1">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM99618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18140" checksum="79E3D160CD9F770A" modified="2016-11-30" version="1">MYGMVHYGRVELLSHDLSHKYLQMKWNAYGKYIHFSHLILYLCYLGILTSFASGYLKRDRAGGGVTTPPPVVTTGVVDYLDRSRTEAPLPEIDLLGLVSNRTLPGNTSGNKATHIHSTQQPSAKSSTSSSINGSWNAVGKEHNEFSRPGNDEDEGGRGEIRYTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3C4</accession>
    <name>A0A1D2N3C4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrator complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06903</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000256">
        <property type="protein sequence ID" value="ODM99768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3C4"/>
    <dbReference type="STRING" id="48709.A0A1D2N3C4"/>
    <dbReference type="OMA" id="DRDSIWX"/>
    <dbReference type="OrthoDB" id="18190at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016180">
        <property type="term" value="P:snRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056235">
        <property type="entry name" value="INTS4_8HBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057412">
        <property type="entry name" value="INTS4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20938">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20938:SF0">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24493">
        <property type="entry name" value="INTS4_8HBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25458">
        <property type="entry name" value="INTS4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTS4 8 helical bundle" evidence="3">
        <location>
            <begin position="357"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 4/Protein SIEL C-terminal Ig-like" evidence="4">
        <location>
            <begin position="562"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="695" mass="77599" checksum="DDC22E5BB05B544D" modified="2016-11-30" version="1">MVPTPSGGGEKMRLVDDAFAKICHAINDPCVQVRVLAATLLGKMPQVGQNFLDQTLDKKLMSDMRRKRSAHERQWEKVKSGEWSSGKKWADDAPQELIEAASVSLISSGAAGAFVHGLEDEFLEVRSAAVDSLCTLAIKSPDFANLALDFLVDMFNDEIEDVRLKAIDSLTKISKYIVLWEDQLETILAVLEDSSIDIREGLHKLLAVCHLMTKDCVKMCLDHILENLKRYPQDKKSIWKSLEGVGKNHPWVVLPLVPQLLSMHPFFDTSEPDPEDPAYVSVLILVFNSAKGCPTMATLFDEKLLRHYHYLRDTLPHFVPELNISNESITGTSDKQIASSSSGSGTSIGGNTNGRLILKELTAKLKSSSNLNSEMKTRLCKLILKDLKRLSEVDQEISAIAKFSSLYIKAQLVYTNCLSSSAWIQLTQNTQNEPLRLQIQSFMQLCLKMQYGFTGLSPKEYGIVMQLKLRALAFQLVYIVRGSNASALAICQNLLEQAETVQKYLEENNLTPDEFTFAMLKMLDSLDEPKPGTVAKHLLPLFEAHQIPLISFSSSIKMASATIIEPTGESDNALKFTAGLLLGIPVDAEIHNLEDTSYVRIMINYPDQQVHLICPRAQDFRSDSNGEVRLLTTISISHQAWTEACPVTISIVLDLRGPETNYNRKLMWKKDSTYIIQLSEEKQVLVSPKPAKRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Z3</accession>
    <name>A0A1D2N3Z3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000242">
        <property type="protein sequence ID" value="ODM99982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Z3"/>
    <dbReference type="OrthoDB" id="8062658at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905002" evidence="2">
        <location>
            <begin position="22"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="630"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="778"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="805" mass="89530" checksum="A84B211C0D259F74" modified="2016-11-30" version="1">MRSAILFTLAIFSLSIHLTSGGIFRRYVRKHRPEGGHRLPQHMIMSRSRMGPPLVERQFRIRQRPWNMFVRRPRAPAWPPILYHYPMQYSPMFQTTQPRMNMRASRRFRFQEQSSRVPQFHHQPLGARHHHPIGISTTTRLPTTSAVQWRPLDYGNPIDRDPTYDYAPPAVERVRFVTEVRGRQPTARANTGMIGMYSRPTPVIVPAPWKRDPNVLARHPILSQQHLHLPQQHQQQLQQHHHHHHQQQQQQHSHAQQHHLPPPPPPRGAFPLWKILSHKQRPRRPQRPVRPQPPRFIGQDPKHPLYHHQVYQEEAEVHPHIPNIVYFQPTDVVPTKNQGKTKVNPKPGLKPGSVASADLYSAEVASASEFKPIHPTRTSSANKSAQSSGNKGYKFTVVGYSGPVATTPMSPVASAPYTTTLRPPTVFYAVKTTPETLSTTHNSVVKPLEPTESLDAQEEAEAASELRPVHVLPNNIPEVEDGREQGAMEDVDFDNTDDSDSQAVPVVPNSFNVFESLLSSFEKEFGNVDEEQDNEEEILEVKDNHHHQRIPVFEPVEEASSGGEVAEPTTPTSARNNNFETSTSISMSVGVSSSSTTSKKSSNTKKEEDEKSVAADDDTDGYFGIRLAPSTTSSTTTSTTTTTTERPVTTSRTTESTTTTTSTTAKSTSTAYPRLPTMPTYKRKPTPVYARKSSKAGGLLSKYSSSSSSISKEVSATGGGVPNGSGEVVIITAGRSKVKEYKPQVIANQTHLLAFDKVVADGEGVKESPIIGAESNASPSSTSTTKSPLEEFDAMQLLHSWLNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4K5</accession>
    <name>A0A1D2N4K5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_06473</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMTC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000224">
        <property type="protein sequence ID" value="ODN00207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4K5"/>
    <dbReference type="STRING" id="48709.A0A1D2N4K5"/>
    <dbReference type="OMA" id="ENCYQRI"/>
    <dbReference type="OrthoDB" id="66906at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000239">
        <property type="entry name" value="Transmembrane and TPR repeat-containing protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000528">
        <property type="entry name" value="Transmembrane and TPR repeat-containing protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013618">
        <property type="entry name" value="TMTC_DUF1736"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44395">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44395:SF1">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08409">
        <property type="entry name" value="TMTC_DUF1736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 16" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1736" evidence="19">
        <location>
            <begin position="135"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="324"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="444"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="478"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="549"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="652"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="712"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="765"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="793"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN00207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="831" mass="94495" checksum="E672C865CC6D0B42" modified="2016-11-30" version="1">MEVTGVVGRAETLSAIFFILAFTVYVKATVKRSITDWKLMPGCSLLVMIAMLCKEQGITVLAVSVLWRTLTSCKYYNVEFILQSVTYERLSSPTSYGAQRKRVFALLDFTSDTTHVCPSSHSYAPTFGRLLVMGSQLPIFTRFDNPASVSETPTRQLTYNYLVALNVWLLLFPCDLCCDWTMGTVPLVESWWDPRNLVTLGTYAVLFSLAHSALTRHTDRHSNLILFGLSLIVFPFLPASNLFFPVGFVIAERILYVPSMGFCLLVAYGWTRIYSSQKCRRKWCWLFLASLLLIHGTKTHIRNYDWESEYSIFMAGLRVNLRNAKLYNNVGHALESQGNYDEALYYFQKAVSVQSDDIGAHINVGRTYNNLKLYKEAEDAYLKASLAKSLLPKAKPGESYQARIAPNHLNVFLNLANLIARNETRLEEADRLYRQAISMRADYTQAYINRGDILLKMNRTKEAQEVYERALFYDSSNPDIYYNLGVVYLEQGKPSQALAYLDKALDFEPEHTQALLNSAIVLSELGDPSLRPMAKQRLETLVARDPKNERAYFHLGMLAMDERDGDSAEKYFRQAITLKEDFRSALFNLALLLADSQRPLEAAPYLNQLVKYHPDHIKGLILLGDIYINNIKDLDMAENCYQRILKMDPENVQGLHNLCVVYVERGDLLRAEKCFIRATQLAPEEEYIHRHLKIVRQRIAKLTAALNQNANMPQKSVMEKSQTDYPPPIIGDDDDALLDALPENDPYFNQHGHRHHHHANEHLPSSSSSTTSTSTSGRHHGRKRRSIGEESPSDISRSHQNGKNSPPVHIDYSAENTSTKDCLADNGKMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N565</accession>
    <name>A0A1D2N565_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-binding protein creA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_06477</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000224">
        <property type="protein sequence ID" value="ODN00205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N565"/>
    <dbReference type="STRING" id="48709.A0A1D2N565"/>
    <dbReference type="OrthoDB" id="10064525at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="466"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="347"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="502"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="559"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="666"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="559"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="666"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN00205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="745" mass="81777" checksum="C087FBFA1D3C0A27" modified="2016-11-30" version="1">MEVLIEKKMIDEPVMIQLDHHGKPRAPPTELEPCEEFPILYGLLTAPKSFKPKNSEELQFLPHELSGGVNGVVMGRVQLLNSRPVVDSDIISMEEADSQNLDFCREDSGASSRSSSCSPQMVDSSSNLSTADENDSPIFLNYLSERRNRNSRSGNRGDSMSDDESSMVSSPGGSSAGGDECLDDNIPTSTTSGFKRKASRLETAIGNIVRRRRVQKRVSPNSSSNYNNNNSSMLSVPISMAPSSPTVSTTCVDPPAPSSALSQQNSSRGRSEILERILRSSTTNTVNNPAASQQQQLQPSGRDNVPRNEGRRHNDSNNNNDSSYEPYAKLRDLLTMSEDQLVKRRRIEYGLPNSNNKTGGGEHDTGRGGREYSPPRNNILASLLQKGRQFDPPRGGRYPLENNAVIRNNNSSPGIVSINLNLSDSNDSSSNGNDERPYKCSLCDLRFKKLPLLNRHVKTHSHIKRYVCRFCSHAFKRSDNLLAHMRTSCKGIKEADAKFAGGVRQPASGTQQGQIIPSLLSPSSSPSLNNGSAAPSSHSVSRSQLEEALLSLRGQNDKIYNSNQNSNSLVSTTTASPPPRVVRRQIIQPGPDFQSRHSKLLEILSGSPVIPNSNLEDEMPLPLSLKVERCSASSPSSLSPSSSQSQLLRSHQRTLYYNNLVKQNELPDEDSQTEEEEEEVHESEQPLDLGSSRVLPPVQPITTPPTVPSVRSRDHPEIVSILSRQPKNVVMMAPDLRKFVGIDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5K9</accession>
    <name>A0A1D2N5K9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000202">
        <property type="protein sequence ID" value="ODN00512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5K9"/>
    <dbReference type="STRING" id="48709.A0A1D2N5K9"/>
    <dbReference type="OMA" id="NARVETQ"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="966"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="878"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1070" mass="116481" checksum="338172D5C84F9E8B" modified="2016-11-30" version="1" fragment="single">DPDKLNSGQPKNARVETQEERQWKQIQMRQQQPQQSVALPDQRLQGDQHKDSVLAGSTVTLAGAPQMTFSPSVSGAMGVNQRMMPPGSPVSTGMDCVRQALQGPHSPSPMGRPFPGSLPLGRPRPPNMTVPMPPPSPSGVYSSRPETPNNAQNIRGQMYPRLPFSHQPRQPLSMQNDVYGNPPTPQSDSVPQSPLGPRSFEQDNMVPSDSYPQKVMADQFSHSPVPQGNEQDVNSVPRPNPSPQTPEAKQHLRGLLINLQDKRLHQESVVQSPGDVSGNRPPVPWQQQHDDPSKLQGVDSKLAQRLGVPNAQTVKNVNVGEFRHPLLPSHVRVPGNVTPMSPLGGQRPMGEYRLGSPVGPGSAHNMDPRARILLHHQQRGILVQPQQVISQRPTGFNQYGGNPPMRNPLDPFDHLVVQQPRMPMSSVSASSSTMLAQQLGRPLNTTIQHVAPPANSPQLSPHHIHSPHQPSPMISGVTAGDAASPAGLAADHQELPDSVTEELEKLEQEHSDHGVEGEQSELADLGMDDDELLGMGDDFNILEYADSELDDVVGGGKTNILDNLDLEEDDKEEKELQLKKETEKNEKKVIPKEFPSLSKNSGITKAITAHSAAAEAAAALSNQSNVSILSPPSQNFIHSAPGEPQILRPAPPPPPYPGPPPPYPGRPQMGIRNGCGVIPNIPSVSALSGGLRNPISGVGVGIRPVQPSLASPPMPSNANPHLHLSQRRTLLLQEQPLLLEDLLEQEKREQQKQIPAPGLMGAAPEEPLLSDFDFERLKADVLSSSNLPVSLSPPNVVGQTVALPTQQGVFVRSAPTLGQVHSSQSGPTWQMESGPNGTLLPNPQQNSMDPSTVHTNLQSGSLQGPNQPGGPRMHLTSLPPPPNPPEHPTTEQERQQQFQYEQWLYHQERVLEMQLKGVEGEVTKLRKQKKAINCKLRQLKKTGAQLNDNDNMELERIQRELPGLQKQLEQARKQARQHSHLSQDYRTKQQKKQQLMGMNPGNQGPTPQNNLSTQMSPLGPSASSPLHSTPQSPMLSSSPSMSGPSPSPLMQHSPMASPLTPRPHHRQQWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7D0</accession>
    <name>A0A1D2N7D0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-alpha-acetyltransferase 16, NatA auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05793</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7D0"/>
    <dbReference type="STRING" id="48709.A0A1D2N7D0"/>
    <dbReference type="OMA" id="MEMRADY"/>
    <dbReference type="OrthoDB" id="10263032at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000003">
        <property type="entry name" value="N-terminal acetyltransferase A, auxiliary subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021183">
        <property type="entry name" value="NatA_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF2">
        <property type="entry name" value="N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12569">
        <property type="entry name" value="NatA_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000422">
        <property type="entry name" value="N-terminal-AcTrfase-A_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="588"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="764" mass="89236" checksum="435F73D7AB4DA517" modified="2016-11-30" version="1">MTPNPVTVKSLPPKENALFKRILKCYEQKLYKNGLKFAKQILSNPQFADHAETLAMKGLILNALGRREEAYEYVRRGLRNDLKSHTCWHVFGLLQRSERKYDEAIKCYRNALKWDSQNIQILRELSIVQIHTRDLVGYRDTRHQLFKLKPGQRASWIGFAIAYHLMKDYEMAFKILDALRNTMNQDNQQMQQGRKDATFEYERSELLLYQNMILEESGDILGAKKHLLDHNKEIIDRVAFNETIARYHIHLEEYVQAETIYRKLIQSNQENKVYYEGLMRSLRIEEEPEEKSKLFNELKAQYPRAALVKRLPLDFTEEAQFTDLLRPYVISALEKGAPTLFTDLRPLYKNPSKVVIIQNLVEGFVTQLEKNSKFSEVDTERAPASGLLWAYYYLAKHYDHIGNTKTALHCVNKAIDHTPTLIELLTCKAKIYKHSGDITAAVENMNDAREMDTADRYLNSKCAKYMLRADKVSEATEILGKFTREGTSPMDNLNEMQCMWFQTECARTYQRVGMWGEALKKCLEVDRHFHEIIEDQYDFHSYCLRKMTLRSYIKLLRLEDILHSHPFYFKAAKVAIDVYIYLHDNPLKNQSSDEQNNQENLSPSELKKLKNKERKAKKRAELEQQAAAAAAEKKNLHQKQKQTNEDGESHHPDSAEELVPDKLAATVEPLQQAMKFLEPLLSLAAHNIETHILAYEIYSRKDKPLLMLRSIRRALKVDPDNDTVQRLLVKFQETMSTRVKTLPEPLPEFMKKELEKVYAFKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7H4</accession>
    <name>A0A1D2N7H4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05467</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000167">
        <property type="protein sequence ID" value="ODN01213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7H4"/>
    <dbReference type="OMA" id="FWERIVT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050909">
        <property type="term" value="P:sensory perception of taste"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013604">
        <property type="entry name" value="7TM_chemorcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21143:SF121">
        <property type="entry name" value="GUSTATORY AND ODORANT RECEPTOR 21A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21143">
        <property type="entry name" value="INVERTEBRATE GUSTATORY RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08395">
        <property type="entry name" value="7tm_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="49456" checksum="355335DEC3F30037" modified="2016-11-30" version="1">MIESKLLSSTEWAFLSPRLFCYWPFTIRPSANGAKKIHSCYSWNYGIPLSATFLLLNIIFLSFYGRIKGNAYFNNKSLMAFDVYCIVVWDSIIMTNEIVIRIYCLLNLHKLNKFWERIVTLTTNYFEHSSQPDVVEHGLRQINNWAKTWTLLNFALVSVHLSCFIYPYISGDEIRRGEDGFAAFMNVYMEVVMCFHNVDVLFLIYFIKIMILGFDLVSSKIQETVRFNLIQREARLMLSRKKSSGTELHKETLPEMKSEIWVNSELTPTLNLLQTLENIVESFNETFSINMLGVVIMVMSQAIFAVYFLYCDPRSITSFTWAVSLITPLILCPCSLVSLCFSASKLADKCYGIMRQMQGIPLSCMSREDQWSVQLTVTRLSGKGVGIYVGRLFQIRASLLTSAVSTFATYFIIIIQMQISSRSQKINNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9S4</accession>
    <name>A0A1D2N9S4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoglycolate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000130">
        <property type="protein sequence ID" value="ODN02003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9S4"/>
    <dbReference type="STRING" id="48709.A0A1D2N9S4"/>
    <dbReference type="OMA" id="PPMHRET"/>
    <dbReference type="OrthoDB" id="413953at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF93">
        <property type="entry name" value="FI11325P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="353" mass="39227" checksum="6FF405230CBB49B2" modified="2016-11-30" version="1">MILRSGAALIGRYLKDCRKVFSSPSYSISSNFASMESKHVQNGNALSLASLPKEQLTSFMQDIDAVMFDCDGVLWLGMDPLENAQALVIKLRSMGKKVFFMTNNSTRTQEEFLEKFNKLGFEASVDEIVGTAFLAALYLKECGFKDKVYVIGSEGITKELAKVGIDSLPIGPDAVDPTSLRWNPQDYNIDLDPSVGAVIVGFDHHISYTKILKAASYLNNDKCLFVATNTDEQFPARGLSSIVCPGTGTFVNAVKTAAGREPVVMGKPEPFPFEYVQRKHNLQPNRVLMVGDRGNTDILFGRECGLWTLLVMSGVTDINSMRRWETSQDPAEKMCVPDYYSQDVNEFYKLLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB39</accession>
    <name>A0A1D2NB39_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Proton-coupled amino acid transporter 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000111">
        <property type="protein sequence ID" value="ODN02463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB39"/>
    <dbReference type="STRING" id="48709.A0A1D2NB39"/>
    <dbReference type="OMA" id="WIRNISK"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF349">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="70"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN02463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="487" mass="53916" checksum="14E8081C77EE202B" modified="2016-11-30" version="1">MSKEEVEPLLLQTDGSDGHGSQDSDEPMYPHKKGAKTSTVISLQKPVAEHDYSITGEHYDPLTERDIEHPTSNCDTMIHLLKGNVGTGILAMPDAFKNAGLAVGTIGTVMIGLICVHTMHILVRCAHDLCRRTQTPTLSFAEVAEVSFKVGPPPLRRFSSVARMTIDSFLCVTQLGFCCVYFVFVAQNLKHVFDPYMGTWPLQSYMALLLLPMILLNYVRNLKLLAPFSMIANIFMAAGLGIIFYYIFRDPLPPIHRPEFHSGFASWKQLPLYFGTAIYAFEGIGMVLPLENSMKTPLDFGGWNGVLNTSMIIVGCLYTAVGFFGYLKYGDLVAGSVTLNLSTGEVLAESVRLMMALSIFLSYPLQFYVPMDIMWPSIKSRIPTERMQLISEYAFRTFLVILTFAMAELIPNLGLFISLVGAVSSSTLALIFPPLINILTTWNAGYGKFRWELWKDISLMIFGGIGFVAGTYVSLEQILHGEASKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDE9</accession>
    <name>A0A1D2NDE9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Eukaryotic initiation factor 4A</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase eIF4A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_03398</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDE9"/>
    <dbReference type="STRING" id="48709.A0A1D2NDE9"/>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045495">
        <property type="term" value="C:pole plasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 19" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="77"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="258"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODN03283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="419" mass="47612" checksum="06B1DB3F295B36D4" modified="2016-11-30" version="1" fragment="single">IYSRGEQDWADSRNGPSVKDAPPKYDGPAGMDPEGLIESSWDQVCTSFDEMELNQKLLRGIYAYGFEKPSAIQQRAIIPCISGRDVIAQAQSGTGKTATFSIAILQQINPENRFCQALILAPTRELAQQIQKVVVALGDYLNVTCHACIGGTNVKDDQRKLENGVQIVVGTPGRVYDMITRRSFRTDHIKIFVLDEADEMLSRGFKDQIYKVFKCLNTDTQVILLSATMPPDVLEVTTKFMRDPVTILVKKEELTLEGIKQFYVNVEKEEWKLDTLSDLYDTLSITQAVIFCNTRRKVDWLTQRMREKEHTVSAMHGDMDQKDREIIMKEFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTDEDKRTLKDIEEFYNTQIVEMPSDVANMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDQ0</accession>
    <name>A0A1D2NDQ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Partner of bursicon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000076">
        <property type="protein sequence ID" value="ODN03367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDQ0"/>
    <dbReference type="STRING" id="48709.A0A1D2NDQ0"/>
    <dbReference type="OMA" id="ECKCYKC"/>
    <dbReference type="OrthoDB" id="786951at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031395">
        <property type="term" value="C:bursicon neuropeptide hormone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005184">
        <property type="term" value="F:neuropeptide hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034441">
        <property type="entry name" value="Bursicon_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41151">
        <property type="entry name" value="PARTNER OF BURSICON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41151:SF1">
        <property type="entry name" value="PARTNER OF BURSICON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905411" evidence="1">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="16024" checksum="C5DDE277E6C784F7" modified="2016-11-30" version="1">MRETRTSWSLIGMCMILFVVGEQISRGMGCETLPSSIHIIKEIYQPSGQMERTCEGEVAVSKCEGSCSSKVRPSAVSHTGFYKDCQCCRETTLRSRSVTLNKCYDPNGKTLTGDKEKYVINLKEPVDCRCYRCGDLPNTSSIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE09</accession>
    <name>A0A1D2NE09_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein 12B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE09"/>
    <dbReference type="STRING" id="48709.A0A1D2NE09"/>
    <dbReference type="OMA" id="RCTVEIC"/>
    <dbReference type="OrthoDB" id="10062424at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056953">
        <property type="entry name" value="CUT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560">
        <property type="entry name" value="CYPHER, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560:SF1">
        <property type="entry name" value="MINIATURE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25057">
        <property type="entry name" value="CUT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00241">
        <property type="entry name" value="ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="691"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="ZP" evidence="3">
        <location>
            <begin position="25"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="762" mass="85598" checksum="5F3E92C3E279849A" modified="2016-11-30" version="1">MTSWHLSSSWERPTGMPNIANLEVMCGTQHMEVHLEFDSPFHGLVASKGMYGHEGCVYVPPRSGKNKFVFNIYYDKCGTKPDNHGKFYENTVVVQYDEELIEAWDEAKRLRCEWFNDYEKTATKTSPMVISDLEIVELNFHGDNVDCWMEIQEGKGPWAPPLTGIVPLGSTLTMVIAVKDPTGEFDMRVKDCDASDGQSGNLLSLSDTDGCIVRPKLIGKFAKLKMDDGRATVMTYAFLSAFKFPDMLNVHLRCTVEICRHGCPEHCSKLPPPPGSHIADVHGQFSDQEPIAVQSQVSQQKVKPNSIEETADGQSEGPEQVSRDKPDIHEEAQRVQKLHEEQQSSEEVRRPPPPQQHQGLPPPQHSQRHQHFQPPQQHQGPPMRYPSQQPPEMYSQHPPQMMHPPPPRYFGRGGPPQGPNGPPPPGMFRQPPRKLIPPGLMRQRPDIAPFQQHNHPNFRHSLPPMPSAIPPAFPSQMYRESTAPEQTIMEQHLRQQVQAERLQSMLMKPEHKTEEEISHEDTVSRKGEPTKDTNEEAENVEDSINEEEEEEEEEKEVPQKEEVTNQKQEQEHKQERAPVPVSNPRESLISQPQALKGDPIESIEDDSLSAEKAAASPLRTMFPKGPRSLRRRRSVSGSTDTIGVQGAFRVVSQADLNFALNATTTQSQPTVVLRGKMRSEDLVYGICLPRMGFGLIFFGLGVAVLVAILIASFLAYAHYSIHHLQMSQQKRSGVSGGPMASLPMAPPPQVLPLPIIIFKKMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE38</accession>
    <name>A0A1D2NE38_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">POU domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_03437</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the POU transcription factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000081">
        <property type="protein sequence ID" value="ODN03236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE38"/>
    <dbReference type="STRING" id="48709.A0A1D2NE38"/>
    <dbReference type="OMA" id="EDATIMC"/>
    <dbReference type="OrthoDB" id="6358449at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000056">
        <property type="entry name" value="POU domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.40:FF:000007">
        <property type="entry name" value="POU domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013847">
        <property type="entry name" value="POU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000327">
        <property type="entry name" value="POU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050255">
        <property type="entry name" value="POU_domain_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636:SF70">
        <property type="entry name" value="INHIBITORY POU PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636">
        <property type="entry name" value="POU DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00157">
        <property type="entry name" value="Pou"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00028">
        <property type="entry name" value="POUDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00352">
        <property type="entry name" value="POU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00035">
        <property type="entry name" value="POU_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00465">
        <property type="entry name" value="POU_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51179">
        <property type="entry name" value="POU_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="POU-specific" evidence="12">
        <location>
            <begin position="142"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="11">
        <location>
            <begin position="238"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="240"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN03236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="33433" checksum="21B24A4E27CAD27B" modified="2016-11-30" version="1">MQGDLFGGLNDGLLSRAEALVDIGKHPGASPPVTGLPQLKHDMMYHPSMGPPHPDGASRYGWTGHARSHFVNNNDDEFGPDDLRIDLSFSCPHTCPTPPVVRVHAFCCMNSMMAAAASHPSLPHPHGHPHSGHPHPAVGMHDADTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAWLEEAEAQARSKRRDPDAPNVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFAAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE40</accession>
    <name>A0A1D2NE40_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Replication factor C subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03177</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE40"/>
    <dbReference type="STRING" id="48709.A0A1D2NE40"/>
    <dbReference type="OMA" id="GATKYIQ"/>
    <dbReference type="OrthoDB" id="10249205at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000011">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000032">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000129">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF20">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="69"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="360" mass="40124" checksum="C3AE12A5C8D4236B" modified="2016-11-30" version="1">MDAFLKTGKLGKSVPRSSESGVSGASQKDSKKKSWPVPWVEKYRPRNIDDVVQQEEVVAVLGKILTGADLPNLLFYGPPGTGKTSTILAAARQLFGDNYKDRILELNASDERGISVIREKVKKFSQQTASATLPDGRPCPPFKLIILDEADAMTVAAQSALRRTMEKETKSTRFCLLCNYLSRIIPPITSRCSKFRFKPLKDDMILQRLEKICSEEGVRFESGVLKSLIKACEGDLRRAITSLQSCHRLKGKDHVLTIADVEELSGLVPMERIEELFTACQTGNYDKVDDVVEKMSRNGLPAAKVLDQFFHFVLDNEQLTDAQKATMFQKISECNFRLMDGGSEYLQLMDLGTTVMLSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEY4</accession>
    <name>A0A1D2NEY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="35">Peptidyl-glycine alpha-amidating monooxygenase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="35" type="ORF">Ocin01_02876</name>
    </gene>
    <organism evidence="35 36">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="35 36" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="35">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="25">Peptidyl-alpha-hydroxylglycine alpha-amidating lyase that catalyzes an essential reaction in C-terminal alpha-amidation of peptides. Mediates the dismutation of the unstable peptidyl(2-hydroxyglycine) intermediate to glyoxylate and the corresponding desglycine peptide amide. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>a [peptide]-C-terminal (2S)-2-hydroxyglycine = a [peptide]-C-terminal amide + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:20924"/>
            <dbReference type="Rhea" id="RHEA-COMP:13485"/>
            <dbReference type="Rhea" id="RHEA-COMP:15321"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:137001"/>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
            <dbReference type="EC" id="4.3.2.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:20925"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>a [peptide]-C-terminal glycine + 2 L-ascorbate + O2 = a [peptide]-C-terminal (2S)-2-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O</text>
            <dbReference type="Rhea" id="RHEA:21452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13486"/>
            <dbReference type="Rhea" id="RHEA-COMP:15321"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
            <dbReference type="ChEBI" id="CHEBI:59513"/>
            <dbReference type="ChEBI" id="CHEBI:137000"/>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
            <dbReference type="EC" id="1.14.17.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="28">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
        <text evidence="28">Binds 2 Cu(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="28">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="28">Binds one Zn(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Endomembrane system</location>
            <topology evidence="22">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="26">Belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="35">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000063">
        <property type="protein sequence ID" value="ODN03814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEY4"/>
    <dbReference type="OMA" id="AGDEMCN"/>
    <dbReference type="OrthoDB" id="10018185at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004598">
        <property type="term" value="F:peptidylamidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004504">
        <property type="term" value="F:peptidylglycine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14958">
        <property type="entry name" value="NHL_PAL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000054">
        <property type="entry name" value="Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.310:FF:000005">
        <property type="entry name" value="Peptidylglycine alpha-hydroxylating monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020611">
        <property type="entry name" value="Cu2_ascorb_mOase_CS-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014783">
        <property type="entry name" value="Cu2_ascorb_mOase_CS-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000720">
        <property type="entry name" value="PHM/PAL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680:SF14">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00790">
        <property type="entry name" value="PAMONOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00084">
        <property type="entry name" value="CU2_MONOOXYGENASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00085">
        <property type="entry name" value="CU2_MONOOXYGENASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="28" id="KW-0106">Calcium</keyword>
    <keyword evidence="14 28" id="KW-0186">Copper</keyword>
    <keyword evidence="21" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="17 29" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="19" id="KW-0456">Lyase</keyword>
    <keyword evidence="16 32" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 28" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15 35" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="20" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="36" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7 32" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 32" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 28" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="32">
        <location>
            <begin position="788"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase N-terminal" evidence="33">
        <location>
            <begin position="49"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase C-terminal" evidence="34">
        <location>
            <begin position="187"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="30">
        <location>
            <begin position="484"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="30">
        <location>
            <begin position="538"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="30">
        <location>
            <begin position="610"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="31">
        <location>
            <begin position="352"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="31">
        <location>
            <begin position="761"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="31">
        <location>
            <begin position="839"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="31">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="31">
        <location>
            <begin position="846"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>C-terminal Xaa-(2S)-2-hydroxyglycine residue</name>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="499"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="566"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>C-terminal Xaa-(2S)-2-hydroxyglycine residue</name>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="614"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="630"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>C-terminal Xaa-(2S)-2-hydroxyglycine residue</name>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="712"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="713"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="29">
        <location>
            <begin position="65"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="29">
        <location>
            <begin position="213"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="29">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="29">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="29">
        <location>
            <begin position="626"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00050393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00057118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00061296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="PIRSR" id="PIRSR600720-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="PIRSR" id="PIRSR600720-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="PIRSR" id="PIRSR600720-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="33">
        <source>
            <dbReference type="Pfam" id="PF01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="34">
        <source>
            <dbReference type="Pfam" id="PF03712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="35">
        <source>
            <dbReference type="EMBL" id="ODN03814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="36">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="868" mass="96258" checksum="B8B131A7C72F22B2" modified="2016-11-30" version="1">MANILTSLSSRLTNYGISYNSALLLVLINLSLICDCTLREGVEAEHSLDIAMPDVRPTKDDHYLCTALNIEAYGTQYVHSFEPNSNADRAHHMLLFTCDDVPEMLRKDGWWDCGHHYQACKSMRIIYAWAKNAPPTVLPKDVGFRIGAESNIKYLVLQVHYAHPLPVGSTDRSGFSLHVNSEEPKYLAGIMLMYRSMLDIPPFQEKIHGDMNCALETNSPIHPFAYRVHTHKLGVVVSGYRLDPNNGKFETIGKGNPQWPQAFYPTKTNVTINPKDYIVAQCTFSTKNFEKPTQIGMTAGDEMCNLYLMYYTKSRDPEEHNLNCGDEENAEITAHIPPDSDVPLPRNKTLEEHAMGHHSSPSTEKTSHSKKRPGIEFNSTPKLGVSDEEPGNGDTTTHRFVVYGGGGRSLKESTFKAINSWPDSSITIGQASGVDFDTAGNIVVFHRGDRVWDYHTFDARNNYAQKEKGPIKTDTVLIIDPSSGKLLHKWGKDLFYMPHDITVDNKGNFWLTDVALHQVFKFSPGSFKPSMILGKRFEPGSDNSHFCKPAAVAVMSNGDFFVADGYCNSRVIKFNSRGEKILEWGRAYQPNLLDGMQSWFSRISPPPYAFQIPHALALAEEHDLLCVADRENGRIQCFKASSGEFEFKIESLEFGGRLFSVAYSPANGGTLVAVNGPNGRFQSKTVQGFIISLATREISSVFKPASGFGNPHDVAISKDGNDIYVVEISQPYKVWKFSQNSTSSAFGKQLDMVHTGPVAPSSSVAMAHSADESNSVNSSEPATAEDSFGASVIIMAFLTIPLLLLIGIGSLMRLRDSGCCRRKETKSFSEFFPPSAGFEKLRMDESDSENSDTEVEEFSASMYRKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFD6</accession>
    <name>A0A1D2NFD6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein beta chain, ciliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFD6"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="71" mass="8523" checksum="C2B682E60FE3E56C" modified="2016-11-30" version="1">MAGKKEAPVYEPGVDLRLDFVYGYIIRSFRIKPDKWNKFLSNEDYKAALFDFFENPQTMVTQLRLRYDKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGG9</accession>
    <name>A0A1D2NGG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sex-lethal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02352</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000047">
        <property type="protein sequence ID" value="ODN04337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGG9"/>
    <dbReference type="STRING" id="48709.A0A1D2NGG9"/>
    <dbReference type="OrthoDB" id="266020at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008266">
        <property type="term" value="F:poly(U) RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050686">
        <property type="term" value="P:negative regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000205">
        <property type="entry name" value="Sex lethal, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="127"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="213"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="35441" checksum="6AF96AC7DAF4E2C6" modified="2016-11-30" version="1">MSSTAEEYLKGTKTNELAITGKLGAGDTMSSMKAGKEVDATSTSGSGGSSGIWSTNAPDSSFYIDRGGPMSLGIGDGDKASFPLLTSSGDGSHSLDSSGKRDQDLDMDGRPTVSVSQAGRKYIITKRNLIVNYLPQSFTDRQLFNLFVSYGAIDSVKIMRDATTGYSYGFGFVNFVNEEDGIRARAEMNGAQVENKRIKVSFARPPSDDIKDTNLYVTNLPRSMTEEHLFTLFAPFGEIVQRKLLVDRYTNLPRGVAFIRFERRDQAAAAINALNNYVPEGAEEPIRIRLAEDHGKQKAAYLAGFRAGMGLPSAALYSEGTWNNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGY4</accession>
    <name>A0A1D2NGY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger and BTB domain-containing protein 7C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGY4"/>
    <dbReference type="STRING" id="48709.A0A1D2NGY4"/>
    <dbReference type="OrthoDB" id="10684183at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF23">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="161"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="500" mass="56866" checksum="AA3EC66738CE5C18" modified="2016-11-30" version="1">MEGGSNFQIDTKGACFLCLKVPSTHNGLGCGSFKNYSFRQLSRYLSLDFLKIFNISISLHAFSNSALENSEVTITICVDCCDTTNKFSLFYQELERIQGELNQCVRQVHDIMVSADRNSDTVQQYRQRMIRTNPAQLIEASIAEKLREETIRKCFHKAMGSNTAVKGEKHDKRKPDVKQVRQIPSQPSSSTNGVTFIALQNQGGELQRNSSDKSSSGSNKPTQLQMKKDPDEEVINLSSDDESDSVAREPAIQINSIVDRNGQVYSASGEYLTPRPSLTFNNYSSNPLLNSTAADATINEFIFPSLPSGSSISVSRPTASSSLFPFPKPRMEYKCDICEKVTHSRHYLEQHKRQHTGQKPYHCIHCNGKFVSQATLKIHIVRDHRELLFSQFKDPNTSPQDFKAAVDQLFENYRRSDDRTRPYLCAHCDIQGYLHKRDLQAHMFQYHFDLLASKLQNFQRASNYQMTPHHQQFGEMTSSLMGPELAENGTLKRMRPLDFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHM1</accession>
    <name>A0A1D2NHM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">LIM/homeobox protein Awh</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_01938</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHM1"/>
    <dbReference type="STRING" id="48709.A0A1D2NHM1"/>
    <dbReference type="OMA" id="THERVND"/>
    <dbReference type="OrthoDB" id="10068367at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000027">
        <property type="entry name" value="LIM/homeobox protein Lhx9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF127">
        <property type="entry name" value="LIM_HOMEOBOX PROTEIN AWH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 10" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="13">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="14">
        <location>
            <begin position="112"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="9">
        <location>
            <begin position="114"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN04751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="20617" checksum="DD088978A552C560" modified="2016-11-30" version="1">MRLPETHERVNDSDLSSLGQTFGSAQCAKCSRWISSSDWVRRARDSQAEQIYHLACFACDACHRQLSTGEEFALVEKKLLCKTHYQETVESDESEEQEGGDPDDNTRVRNKSKTKRVRTTFTDEQLQILQANFQIDSNPDGQDLERIAQITGLSKRVTQVWFQNSRARQKKHVGGKHSAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHV7</accession>
    <name>A0A1D2NHV7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHV7"/>
    <dbReference type="STRING" id="48709.A0A1D2NHV7"/>
    <dbReference type="OrthoDB" id="10055432at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41153">
        <property type="entry name" value="RE41427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41153:SF2">
        <property type="entry name" value="RE41427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="383" mass="41568" checksum="7E324941295252B7" modified="2016-11-30" version="1">MNSLKMETVISLCSVGGGGKSSEKSRKNIASHSQLRQLRLGPLIQQSTVLLSLLLVKTVISLNTNAPPHPNGLPSESIDFNGKGKLKYVWGDALADPKALGPDGNPYPWELATKIASKQRNPRTLFAEEFGGADIGLINPETTRQILLRSFEAQEFGGGMNSFFGSLSHSHHHHHAHSHTPSDDNGRQGRSLNRQGHAYTIRGRGNKRVANGPSPSSPNSSPYHHYQYNRDVDPSSSSTTNPNDNEGDASNNNNNTPPPSDGGCVPSRLCPSTYNTTAPLYGISLTSGQPVTIVQKFPDLLQQVVFQVCKTTECDVIHGECVQTYLPYLFLVIPLGPVTLTGQDYVLVESGCVCRPKYASKQDEPPPLPFIQAYNTTKARTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI02</accession>
    <name>A0A1D2NI02_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01808</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000034">
        <property type="protein sequence ID" value="ODN04893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI02"/>
    <dbReference type="STRING" id="48709.A0A1D2NI02"/>
    <dbReference type="OMA" id="VFVCPLY"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF118">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="199"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="402"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="824" mass="93068" checksum="249B017964B25432" modified="2016-11-30" version="1">MVSLIKSKKPYLPIQNGSPAPSSSGMTQVENQTGNERRKKKKKKKKKGNQSFEESLASTSTTAPVGNGDMAVKKAKTFVIGKKKIICDKLLLNMLKKKKKKQLAAALKAKAAVEASKNQGQGSEVVEQIPFSNKRKLSNSGSTKSEDKIPLLQDTEEEDYGEPERERKVIKYKNNQVKANSPGVATPDLPVTECREALIQRFKESDTLIVVGETGSGKSTQIPQFLLKDCSKLFSYRGIAITQPRRVAAISLANRVAYELGTEVGETVGFKVRFDKQVSDKTKITFLTDGYLMMDAIRNKTFDEYSVIIVDEAHERSVETDVVLSLLRNAQTIRKVRNPKKQLKLIIMSATLDVDKFKSFFSLKDHGLTTKAVYVKGRPFSLQLNYLPKTVSESHIDSTWITLLKLHMELPTDHHILVFLTGKEEIDLIVARANAINQRKDLTRVFVCPLYAALSKESQMKSFELPSDNTRKIVVSTNLAETSLTIPGIRVVIDSGRVKSKYFEESLGMNVLRVQLISKSQSDQRAGRAGREFEGAVYRLYTKSDYEKMEGFPAPEITRSNLSRVLLLAAVSLGVNDFNEFQLPDRPSTKAIRYALNELHRFGAIEANQQPVKLTRTAKRLLSFPVELHLARVLYLAVQYQELSRICAIIAMSTVETVYSPDIHEKETRHVKYRALWAPEGDFLTFWRIFKEYKKSKNKKAWCKEYSIQFKTMAYVTQVWRHLLTVCQSMELEEDERLSCGDAVDFKEKLLLIFKTAFSHQIARLSKTGGIYIVENVFDSSIKFHAKIHPTSSLIATKPGRLIFTHLSFNEVDNAVYMHNCGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJI9</accession>
    <name>A0A1D2NJI9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein CWC15 A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01284</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJI9"/>
    <dbReference type="STRING" id="48709.A0A1D2NJI9"/>
    <dbReference type="OMA" id="KYREHGQ"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26683" checksum="69019AD361634BFC" modified="2016-11-30" version="1">MTTAARPTFDPAKGGGGRGEKDLSALSRQYSSRDLPSHTKLKYREPGQGTTDEHKSKDFRREVEDRERQSRRDKEKEASRGRVAPEPASSSSSSAGAIQQPPAKKSKIDPANLDADDPIEDSDADDADEDSDDEDDTAALMAELQRIKKERAAEQAKKEAEKRAEEERIRAENILSGNPLLSYSGTASKGDMKVKRRWDEDVVFKNCARADDKSKTKGFINDCLRSDFHRKFMEKYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKG3</accession>
    <name>A0A1D2NKG3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3 15">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_00949</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="15">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3 15"/>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKG3"/>
    <dbReference type="STRING" id="48709.A0A1D2NKG3"/>
    <dbReference type="OMA" id="SFFDFDY"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07849">
        <property type="entry name" value="STKc_ERK1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000046">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008349">
        <property type="entry name" value="MAPK_ERK1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01770">
        <property type="entry name" value="ERK1ERK2MAPK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 15 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="31"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN05744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="382" mass="44386" checksum="1F8B144557F83388" modified="2016-11-30" version="1">MADNNSNTGVTSNNPNAEIIRGQGFEVGPRYINLAYIGEGAYGMVVSVYDNVTKTKVAIKKISPFEHQTYCQRTLREIKILTRFKHENVSKVAHENIIDIRDILWSPNIENFKDVYIVQCLMETDLYKLLKTQKLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGTPSQDDLQCIINEKARSYLQSLQYKPKVPWEKLYPDADRKALDLLDKMLTFNPHKRIVVEDALAHPYLEQYYDPADEPVAEEPFKLDMEYDDLPKERLKEMIFEEAMLFKKRMEIELQQQQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKI3</accession>
    <name>A0A1D2NKI3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKI3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="15780" checksum="E8BAD09CEBCBA184" modified="2016-11-30" version="1">MWRWPPSDQLMEQMLNSMGYQIPARKQVIELTKMKQSLQLKLKLLLKKRGRLIEKLDEFEDSAARYELLDQDEILPPIPENSSLNLDLMHAIFKNMQFIGSSRDDEGVDLVVALPKPDPITYVLPIQYHDKRMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKK0</accession>
    <name>A0A1D2NKK0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger CCCH domain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_00890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000016">
        <property type="protein sequence ID" value="ODN05803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKK0"/>
    <dbReference type="STRING" id="48709.A0A1D2NKK0"/>
    <dbReference type="OrthoDB" id="3247158at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045124">
        <property type="entry name" value="Su(sable)-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119:SF12">
        <property type="entry name" value="PROTEIN SUPPRESSOR OF SABLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="868"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="897"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="868"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="897"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1019"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1036"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1047"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1061"/>
            <end position="1097"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1112" mass="122998" checksum="6408DAF59F2D3389" modified="2016-11-30" version="1">MRVEHCGDLLLEPSSLHQQPSTISSHCSDHQSSRNIQFSELNQIEVPVIGCKPEFILDNEGQRGVFGFTLSEEEWSLFSKSHLADLEPYERKKMCSLPKSFTPFSSKAVGDGGLESDRNLNRSASNSILLRKCESLNPTPSQFLLNGSEPNNNSIAHPSSLSKILLLHKSQEGFQEDEKENWLGDEGWNGTDTASVAETNAETINDSAPIGDLGTQGSLLWEGFYQIDQNDLKEPEIDVEFLPTTRFPITHSSSVVGTIGSHPNPIISCAADQAHYHQHQDLSTSQKASFPSTVYNFHSIDPVLYAEYDDWNANVASLCENNADSTPVLYPDVLSVNMSGYAIQPAPESGFGSYAAYGDNEEATDSGRAVEEVNTLSTFLSKFDDKVAAIWGQGSARSTLGANLLSVDGCISSASTPLGSSNPWGTPSSDVSTTHGSSEFRLMQTQATKQISLAADALLSGGYALHSNQDHTHFEVQSNSQNANKITICDPTISPPKGNYNIMHSMKQYFGTAPPESEYHIIKRNEAISSAEEMEQSLAAVNHDYENAGFIAFAYPQDPDERQSRMDMNMVARALDSIDDEGDEEWEIVEACTKGKQQGYDEDLLNSWKTHFRTVDQVETIASVRGIDLLESPITAISAHQINPNLPEYRLFDVEVDGEYRVFNRPGQTLFPVKYKVRRQFEKGNQTEELGVGLSPPLDPSQVFQAYKAASEWTQYLSVPNFEFTGTLGTLPQCTTPRDTRIAYECDNTADLQSTDWYSLSKGSEYSGIWGEWVVGEDTSNSLVPGGVEYCDSGVDGVGSRSDYYDDMFGDYEGEFENFSGIGFSFPGFVAANDTDTDYGQFQDAASSIGCDASSLSGKQGKSNRRNKTRLRPCKYYFLEGSCRRGNDCKFSHDSVTCRYWAEGSCLKGHTCPYVHCFIDGKKLGPHDEYGMKATGADKQYHLESETDFPALGSTKNTMLSSRQPMALEFPSSMGEGIRRLEDSLESLTVFTDSNSSVVEEEVNQVETRRLFLFERMRSSPSKSVTTERAHKKQNSGDSGKTNNKNYNEKHQRLDSREWSESSNRTLSKSKSLGDTNSSAPWLRNSVSRSSSHTTGITLGIPVKEKRKKKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL88</accession>
    <name>A0A1D2NL88_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein dimmed</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000014">
        <property type="protein sequence ID" value="ODN05865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL88"/>
    <dbReference type="STRING" id="48709.A0A1D2NL88"/>
    <dbReference type="OrthoDB" id="10039134at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070888">
        <property type="term" value="F:E-box binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061564">
        <property type="term" value="P:axon development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007423">
        <property type="term" value="P:sensory organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050359">
        <property type="entry name" value="bHLH_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290:SF167">
        <property type="entry name" value="PROTEIN DIMMED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="211"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="278" mass="30133" checksum="7D424F018BAE1C74" modified="2016-11-30" version="1">MNVMVVKSNMMSESRTQERSSRGRKRVMREQTSRKQSKQITEPLETIDIDLFDDDIPVSDELMESILNSTGIVGGTSSGGSGAGDDLDDYDEIDTSDDNLDGTSTSSSSQYLRSTRNSNSGSGSSALFSDKEGCSFAGSEERLTSAEKTGGRRRGAGSNSNHSGGGSGGGSSGSVAGDDGSVNGGNCSASEKSGSGERRRKTVMSARERNMRRLESNERERQRMHSLNDAFQQLREVIPHVTMQRKLSKIETLTLAKHYIMALTNVICDMRGEEKPYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLI8</accession>
    <name>A0A1D2NLI8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dual specificity protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
            <ecNumber evidence="1">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EC" id="3.1.3.48" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLI8"/>
    <dbReference type="STRING" id="48709.A0A1D2NLI8"/>
    <dbReference type="OMA" id="HVINCAD"/>
    <dbReference type="OrthoDB" id="253091at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033549">
        <property type="term" value="F:MAP kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020405">
        <property type="entry name" value="Atypical_DUSP_subfamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45682">
        <property type="entry name" value="AGAP008228-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45682:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01908">
        <property type="entry name" value="ADSPHPHTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01909">
        <property type="entry name" value="ADSPHPHTASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="14278" checksum="A353F17FAB44F153" modified="2016-11-30" version="1">MSKEEVRIQVKKVLENESVSHWNHLDQVYPGIFIGDEHAAKDIDNLKRLGITHILNAAFVSSRTNCYDHGIVDTDPDWYAVREYNCEFLGIDAIDNPEFDLSQFFEDAADFIESARCSNGMVSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMD2</accession>
    <name>A0A1D2NMD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase LMTK3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMD2"/>
    <dbReference type="STRING" id="48709.A0A1D2NMD2"/>
    <dbReference type="OMA" id="CMSAKEE"/>
    <dbReference type="OrthoDB" id="5973359at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24417:SF7">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN EAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24417">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE LMTK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="223" mass="25619" checksum="41F18CC0D117DB53" modified="2016-11-30" version="1" fragment="single">MLSDGWRDARMFMKVLTIVCDISFPKGLEWLHTAGFVHPDLAARNCQVSSENRVVIGDYGLGTQIYKDDYHWSSNIAIPLRWTAPETLHCTSSVIQILKVNESSNVWSWGVLAWEICEFGKLPYFELSDDEVISRVIIDKNYFLGMPTLQCMSAKEELYKIMSSCWQADLEHRPGLSTIISCLENLLKTFNVSATPPRDDFESKWEQLGSRTNSEEDKRRKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMS0</accession>
    <name>A0A1D2NMS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein outspread</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMS0"/>
    <dbReference type="STRING" id="48709.A0A1D2NMS0"/>
    <dbReference type="OrthoDB" id="9942268at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052223">
        <property type="entry name" value="Actin_Cytoskeleton_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17271">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17271:SF1">
        <property type="entry name" value="PROTEIN OUTSPREAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="16"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="311"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="387"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="152"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="493"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="59232" checksum="954E1F8B1C2DEA72" modified="2016-11-30" version="1" fragment="single">REAEYTESLKCKDEIIEELRDQLTREISVREKLELQTHELEQQVQLLSEKVAKVQSLLSETERELDQSNINQRELGRITESQQMQLKQELDLLRVRCNDLTEKLYQSEKTAKTLKTKLGRVKSQSLKDRQIESDVICKIHDLEEKISRFDKSPLSPSSTTSGASLSLPPSASLPTSPTESTPGAVTSPGGGNTPGGRDGGIINVIMKLNDLDQRVEKVTESLWFRRGELEDYVGECQNCKILEMEVRERDERLEVLEGNLKKLELEFDKKMQELREFVKEQPPSSQEASPSYHQATNKYQVEIEQLRNLCAKGLEAMENSHRRMIMELEEKHRRELQNLRIEKEQELAEETKATLSALDAMRKNHQLELQREMAKFKEEFMRKFQCNQDLSDLHREHEEELYEVKTEILRLTEKYSLKCVEASKLEETITYLKSQLNEAKRKMIEMEASDFQSCISSVSKVDPSTRPQPKPRTSRQQLQPVEQALPPPPPLQPQQVVPLAAALSPQEIKDQGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMT5</accession>
    <name>A0A1D2NMT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMT5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="149" mass="17618" checksum="03CD8FAAD9092D6B" modified="2016-11-30" version="1">MIFMQVMSLVRELRAFNANLNRSLGIIYVNFFITTLCYYSGTPANLRKSTITKSHWYKGVYFFMSWTTWIWSCEFHRKIQEALRSWIREHKYCSNGQLTQMDIGKMNLLAMEIEHDAMGIVCRYFTVNYSLLFSLLGLLVTYSILAYQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMW4</accession>
    <name>A0A1D2NMW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_00130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMW4"/>
    <dbReference type="STRING" id="48709.A0A1D2NMW4"/>
    <dbReference type="OMA" id="HGGSQWS"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051121">
        <property type="entry name" value="FAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42796:SF4">
        <property type="entry name" value="FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42796">
        <property type="entry name" value="FUMARYLACETOACETATE HYDROLASE DOMAIN-CONTAINING PROTEIN 2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="3"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN06559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="23283" checksum="197E456630AE2808" modified="2016-11-30" version="1">MDKVVCVGMNYIDHCEEQNVPVPKEPIFFSKFSSSVVGPNDPIQYPDMTEELDYEVELAVVIGATGKNIPREKALDYVLGYTVAHDVSARDWQLKRNGGQWLIGKTMDGFCPIGPWIVTKSDIADVHNLGIRCRVNGVTKQDSNTNQLVHRVENVIELLSKFVTLLPGDIILTGTPPGVGVFAKPPFFLKRGDKVECEIDEIGTIENLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMW9</accession>
    <name>A0A1D2NMW9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit RPC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">DNA-directed RNA polymerase III subunit rpc9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_00091</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.</text>
    </comment>
    <comment type="function">
        <text evidence="12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With POLR3H/RPC8 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation. Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the RNA polymerase III complex consisting of 17 subunits: a ten-subunit horseshoe-shaped catalytic core composed of POLR3A/RPC1, POLR3B/RPC2, POLR1C/RPAC1, POLR1D/RPAC2, POLR3K/RPC10, POLR2E/RPABC1, POLR2F/RPABC2, POLR2H/RPABC3, POLR2K/RPABC4 and POLR2L/RPABC5; a mobile stalk composed of two subunits POLR3H/RPC8 and CRCP/RPC9, protruding from the core and functioning primarily in transcription initiation; and additional subunits homologous to general transcription factors of the RNA polymerase II machinery, POLR3C/RPC3-POLR3F/RPC6-POLR3G/RPC7 heterotrimer required for transcription initiation and POLR3D/RPC4-POLR3E/RPC5 heterodimer involved in both transcription initiation and termination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPC9 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMW9"/>
    <dbReference type="STRING" id="48709.A0A1D2NMW9"/>
    <dbReference type="OMA" id="WGMHNLA"/>
    <dbReference type="OrthoDB" id="1746530at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.40:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038846">
        <property type="entry name" value="RPC9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561">
        <property type="entry name" value="CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="14">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN06618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="18330" checksum="D48C88658045284E" modified="2016-11-30" version="1">MESKCGQFDIAEKLVPPEGDQNSKRLIGPLSNYEVYQFFKEVKEGNVRGPKNANKWKFNTHLNTVTYEVLQYLQRTPCIVQSPEIIEEFLTKLHPYNLTKAERLTILNTRPSQPVDIQAIVEESEERLTESQIEEILDIVDSTLPPLNANEEAKTDGPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1M5</accession>
    <name>A0A1D2M1M5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006969">
        <property type="protein sequence ID" value="ODM86857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1M5"/>
    <dbReference type="OrthoDB" id="10254973at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="49" mass="5902" checksum="83B3DC4AD64797D2" modified="2016-11-30" version="1">MQRWGFPKTTMMDLIEGPDTMLRTFWPTFSHMERILIGDEQAERMNQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2S5</accession>
    <name>A0A1D2M2S5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">GTP-binding protein Rheb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_19406</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Lipid-anchor</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the small GTPase superfamily. Rheb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005683">
        <property type="protein sequence ID" value="ODM87278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2S5"/>
    <dbReference type="STRING" id="48709.A0A1D2M2S5"/>
    <dbReference type="OMA" id="SARHNEN"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04137">
        <property type="entry name" value="RheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000273">
        <property type="entry name" value="GTP-binding protein Rheb homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM87278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="21027" checksum="761ED74EAA55878B" modified="2016-11-30" version="1">MPPKQRRIAILGFRSVGKSSLTIQFVEGHFVDSYEPTIENTFNKNTKLRGQEYQLTLVDTAGQDEYSIFPTQYSMDIHGYVLVYSIVDPRSLEVIQVIYDKLLDMTGKVNVPIVLVGNKRDLQGERKISQEQGKKLADSWKAVFLEASAKNNDSVMDIFTTILTQIEKADNNSNGQGSENKSNCVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2V1</accession>
    <name>A0A1D2M2V1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Syntaxin-1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005724">
        <property type="protein sequence ID" value="ODM87262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2V1"/>
    <dbReference type="STRING" id="48709.A0A1D2M2V1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Syntaxin N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="60" mass="6694" checksum="EE015061843D15E8" modified="2016-11-30" version="1" fragment="single">MEVSDTTRMIEDLTTDVEKVKSLHSKILASAISDQQMKADLDDLMSVIKTSSQVIRAKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M330</accession>
    <name>A0A1D2M330_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U1 small nuclear ribonucleoprotein 70 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_19361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005569">
        <property type="protein sequence ID" value="ODM87321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M330"/>
    <dbReference type="STRING" id="48709.A0A1D2M330"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM87321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="81" mass="9243" checksum="F0EAF97E5842B9C7" modified="2016-11-30" version="1" fragment="single">MQMERKLTGRRVVVDVERGRTVKGWLPRRLGGGLGRTRRGGPEVNVKISGRDEPDRDRFRDDKSDRGRDRTGNVKKGPSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M475</accession>
    <name>A0A1D2M475_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferric-chelate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18904</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004706">
        <property type="protein sequence ID" value="ODM87778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M475"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="8">
        <location>
            <begin position="83"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM87778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="320" mass="36391" checksum="56CCD4DFDC439178" modified="2016-11-30" version="1" fragment="single">LSGEGVFWISLPRAGTRPNYPSGRGPPPIQAAEVPEMDSHDNEYSLLEMVDAGNTRCPCPFVPTTVPPELQTKRPVEIEGRRSHVLQMLIGWVILVPLSFFVARFYKETFSKVFFLQEFWWYTIHFLCLATTLIFTAGGIYALKIKRSTGPEYEIVWTDATTIHIYFGYGLIASFILHLLLGAFRAYDMEIRMIQISLHWGLGWLEYAVANVVIMSSMGIPSGILNCTSLVVYIAFLAVQLMFTLGMEVHIRRVDDELALQPPRSYLPSPVMRLFHRDAPHANFRMWILGFFFLVCVAFFTALHLTMDFGFEFSPASQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M603</accession>
    <name>A0A1D2M603_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_18270</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003628">
        <property type="protein sequence ID" value="ODM88407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M603"/>
    <dbReference type="STRING" id="48709.A0A1D2M603"/>
    <dbReference type="OrthoDB" id="3069995at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000016">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000111">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="643"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="688"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="773"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="851"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="910"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="939"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="968"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="382"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="423"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODM88407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1029" mass="118846" checksum="1E12310D2FD2F54E" modified="2016-11-30" version="1">MANCRKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVPKYFVRYNGNKNAVDFVLMWFWLALPCILRSCSEHNTGERGPQPTAPHSQALVQTESSTFYSHQLNQTVLNMPPKPVERLPRRQERPKEHFQGDGKKRKHKRKESYAIYIYKVLKQVHPDTGVSSKAMSIMNSFVNDIFERIAAEASRLAHYNKRTTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSNYCPVCGEETPADTTSNATNTGRFVKEPGFQIVFDCFINLFEISDPPWFEKAFVFCSECSRQLTVVYELEKVMKEVERRFKESEKVVKDKLRSSEVKFQSSGVYGRDNRYWRVRKQFLRKDRDPDDSDSETLSAITSPVPSPSTSVPPASHSEVACGRGASENEEEVVLSEALEDNQKRKRRQKDHNSSECQVKRKKKPESEQGEFAHLGTNANVFPTPPLGFESEYNLDEFFQEESYNSSKTPTTLKENEDKELITIEEELKTDNEKRKPELTPEEEEQKALAIARWLTPGRPEIFHNGIRLSKIGDGRQYQCSACDAIILCTKPQHHQQLPKAHVITHHTDFHKCECGERFSNNKSLQKHVNLVHNSIAEEREKRIALVRYCHVCRRPFEDVNELRSHIWTHYSKEEREEALARGEKPEVEKKSFHCDKCTFKFAKEKELLRHLKFAHDPASKKKEELKVLNEKTFSFHGVIITKIDGDKIKYKCSKCGATSPRLGMAKYHVVVKHTKTLKCDHCDMRFAVEYALKKHVEKVHTKDPSSACYCPICGCPYYALKNPPRRHIWTHFSEEDRQDALARGETVPFGVDRTFQCEKCPSSYTCNAALQKHQRESHEGQVKRKICGICGASVAGSLVSHMRLKHPKQEDFRFVCTVCNRRFTQYTRLKLHKQSCHVVEPQFKCEICARGFKLEKRLKEHRLGVHLNQKPFKCEQCPRAFMRRTLLKRHVEGVHEGKKFKQYPRKKRRKQQKKVELELECSEEDEDTSDSDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6N4</accession>
    <name>A0A1D2M6N4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003409">
        <property type="protein sequence ID" value="ODM88584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6N4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="397" mass="44643" checksum="456BCF158C34F6A0" modified="2016-11-30" version="1">MSGSNWNFGENMRKGFQALEEAVDKLKSGATKTEADAEMKKAEDRETRDFLVAELIAAREENAGLVKRSWKVEKVEAEVVPSGDDPQVGGKLPVNIFPIEVWGLMFNNLTASSDLAACSNASPDFRNELKPKRTRFLFEQVLPILINNGTFSPENVFERLLELRTICRSWKAGVDNFLENHPCHQHSMLSDYCTRASNIYSSPSELTDCLQLQHFTGFSSTEEITRCLTVLDELPLHAPKPAFIGRTIVFTEGSWTNQNILEFWAAAQRLLGMDGIGGSIWHCSILDMSPSMLHPHLPLLLQLMPNLKILKLLLKCAGRRVQAVQNSSSLPELAALQVLRVRCCKPCLPRGYQLVSCYPHVKKLELDFYKGERIEYSIMNEPRRIGTHGVISPADRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M795</accession>
    <name>A0A1D2M795_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003110">
        <property type="protein sequence ID" value="ODM88860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M795"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="139" mass="16520" checksum="DDAEBDFA5FF9D8F3" modified="2016-11-30" version="1">MIFQFKAAVYPKLSLEMMKHDVYLLRWIRAKNLDVQLAERDILEMVKFVRVNKIENIMEEDFGDIMDEFPYHMDIVSFKLSPTPTIHVLLNMLRPFFSESTNRALKIFGPNKTKWKPYLDARIDPNKLPEQFGGNRLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M799</accession>
    <name>A0A1D2M799_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003128">
        <property type="protein sequence ID" value="ODM88838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M799"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903568" evidence="1">
        <location>
            <begin position="21"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="16898" checksum="AB2DA5A565AC29D2" modified="2016-11-30" version="1">MLWSLGLVAILADLSFRQWGGDFDLASDITDEEKLNRTTGVNAEILRIYLINNTLIDHDNTRTTSLSKGTTLKFYENPTTHYTESEIIFTSPLPEDYESKPSGRDISGVPGGDANIRGERDDRKILKNGKETQVLLLLKVCGDLKNLLLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7T4</accession>
    <name>A0A1D2M7T4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 1A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_17708</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003009">
        <property type="protein sequence ID" value="ODM88974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7T4"/>
    <dbReference type="STRING" id="48709.A0A1D2M7T4"/>
    <dbReference type="OMA" id="PIWICHA"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="182" mass="20653" checksum="A9DBF2F610CC62E6" modified="2016-11-30" version="1">MLSDLLQTGTTTTNGTLNYGLLFLTLNPDIQKKCQADIDAIVLKHLTPTLEDVEKMPYFQAFVLETHRLGNIVPNPIPRTCPKDWRIRGYTIPKGSIIFSNHYSVHMDKEYWGDPEVFRPDRFINEKGEFVLDKRVCHFGFGKRICIGITLSNAVIPIFIATLLQNFNLSCVPGQKPPTTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8I0</accession>
    <name>A0A1D2M8I0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Divalent-cation tolerance protein CutA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002757">
        <property type="protein sequence ID" value="ODM89275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8I0"/>
    <dbReference type="STRING" id="48709.A0A1D2M8I0"/>
    <dbReference type="OMA" id="VMENHTY"/>
    <dbReference type="OrthoDB" id="2017693at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="DIVALENT CATION TOLERANCE CUTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419:SF8">
        <property type="entry name" value="FI09726P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11381" checksum="2F933B00EC8D371B" modified="2016-11-30" version="1">MELAKSFARDLVQQQLAAIVNIMPMESAVYMWEGQLEEDPEVLLLIYSQECQLPSLEAYIRENHPDEEPGLAALPIVGGSSSFLDWIRNNSMSANDTGNLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M926</accession>
    <name>A0A1D2M926_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002645">
        <property type="protein sequence ID" value="ODM89432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M926"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903650" description="CUB domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="28964" checksum="27AB898ED70AB16B" modified="2016-11-30" version="1">MNIKGILLTCFCTFFHFSTSESTSCGQTIIADNGTITYKLADNYDAGELCVFMIKFESGYIDTTFNLDTHGLSNSDSDAVTVFGSFFGLTLAANLGHNQQSVTLTGFGAVVIFRTNSSSGTGFQLSFKPNRIRFPGIYDGTYAVFDNNTLSPLNIPANDTGESLYNYFVFTSGSRLISEPDTFFRLTAKVNFENPDNKCSNGFHVYSFVDELQLEKSICERVDDGVVFEFSTRGLFFVYQDQDGFLPPVSGVITWETDTLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9A6</accession>
    <name>A0A1D2M9A6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">sn-1-specific diacylglycerol lipase ABHD11</fullName>
            <ecNumber evidence="3">3.1.1.116</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha/beta hydrolase domain-containing protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_17132</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>1,2-didecanoylglycerol + H2O = decanoylglycerol + decanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48596"/>
            <dbReference type="ChEBI" id="CHEBI:11152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:27689"/>
            <dbReference type="ChEBI" id="CHEBI:90605"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + octadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:77107"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:25629"/>
            <dbReference type="ChEBI" id="CHEBI:77129"/>
            <dbReference type="ChEBI" id="CHEBI:186738"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + octadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:25629"/>
            <dbReference type="ChEBI" id="CHEBI:52392"/>
            <dbReference type="ChEBI" id="CHEBI:75728"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + octadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:77103"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:25629"/>
            <dbReference type="ChEBI" id="CHEBI:73990"/>
            <dbReference type="ChEBI" id="CHEBI:75468"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,3-diacyl-sn-glycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38503"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:64683"/>
            <dbReference type="ChEBI" id="CHEBI:77272"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01002553">
        <property type="protein sequence ID" value="ODM89550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9A6"/>
    <dbReference type="STRING" id="48709.A0A1D2M9A6"/>
    <dbReference type="OMA" id="FICTRTR"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="12">
        <location>
            <begin position="49"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00043667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM89550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="20543" checksum="09CFE6B62998EEFA" modified="2016-11-30" version="1">MHCNILTKTSFLRRIPTTTCSELHFCRHSSSSSLLSHSIYKPPGSEAGPPLLITHGLLGSKFNWNSIAKATAKATNRKIVTFDARNHGDSPSHDDISYELMAEDIWELAKHLEVDKFSLMGHSMGGRTVMTFALNHPDRIEKLVVVDVSPLDLYSDFPTMKVYLQALYDIGLNLKDTFDTTFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAE5</accession>
    <name>A0A1D2MAE5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16734</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002276">
        <property type="protein sequence ID" value="ODM89950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAE5"/>
    <dbReference type="STRING" id="48709.A0A1D2MAE5"/>
    <dbReference type="OrthoDB" id="8182982at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF299">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="4">
        <location>
            <begin position="32"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="2">
        <location>
            <begin position="282"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="3">
        <location>
            <begin position="564"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="921" mass="105371" checksum="35957E5B32242830" modified="2016-11-30" version="1" fragment="single">ASATNNITSEDHDPEQEIWENLFGKRSERFIPSHYDLELRPIFEEEGKRHTMPGKVLIIGTTMEKTNKIRLDPSSTFSFEQNPEHPLEIKSSSIKVTSNGAPVTIKNVDAKGFYIDLDRKVGAGETIEVYIEYVAKIQQKEFSKGFMHLPCGKDCKEAEIAVTGFNAYAWVVETHCGHIFPCLDNRDYKTTFNLSLIRKNEYQSAANGLLLTTTPHSQLKGWMTDKYTWNTKIRMPLFAFTVFKGYSYEQSYFGKEKKIVKVFAPKEDINKAVNVINVTATAAAKILSFYEEYFGSSSNVQKIELFFVSTSYRDFGTSFMKTMGMNFYNLDDLIPKNEADQSTKLRVIESVVGSLAHQWVGEWWDPEPETSLVFTKALPRFLEYLGLQQIDTALADAAIYKDILEAEAVDRDDENYQSHKDNWSKGTLLLRMMEEVLSKDVLKAGLQTYFNRLWSENGTRVTTEEFYEILQKSTGKGKLPFDIATILGSFVHNVGVPLVRVGIANETHFVFKQERFRYVDSRNKTNDAVWYLPVTYTQGNERKTIWLTPDQNVKYVPGNTSELLLLNPDATGYYRTLYEDSSLLQRLQQQLELNHTEINPLTRAGLLSDFFVFADEKYSSYGAALNLTSYFNEGSANETSLVVWTAFITKFTGTYNKFISHSQYAKMKNFLLEKVNRILEDTNPPKENEQIALRDYLLGVACTLNHPYCETKAKKLFLEWRANSNGASPLDYLYPDSRPILQCAIVANGGQEAYDFLLAKYREAIKAKVSTEEARALVKSLACAPDKPVFQKLLELLLTPPSSGGIEEYNRWFIEDYVLKTPLPNGKEIILPFISKNFDLIDEKLGHRPGESVIPWKIRALTRSWHFSSAEKKKEIQELLKLHEKKFQDEGNLIHVPTLYQELDANIQWMDTHGHDILNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBG3</accession>
    <name>A0A1D2MBG3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Complex I is composed of 45 different subunits This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002085">
        <property type="protein sequence ID" value="ODM90251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBG3"/>
    <dbReference type="STRING" id="48709.A0A1D2MBG3"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12280:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit B 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="7">
        <location>
            <begin position="217"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00071853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="342" mass="38118" checksum="E8BB6321276DC4A8" modified="2016-11-30" version="1" fragment="single">NHKFPILSTRPSRDSQKATKIERGSGQLGTTKSPSSEQMLKPLNSKPTIFRYILKRRSKSLDQLKVSAFGGLNQIRRVPILRSRSKMATLGLMKLGGRFGFRILNGNSGSAQLGAFVNIPFGGNQQNKIYIHTQNANSAPGAVDKTAVRSWEIKDNTKALVPFRNASSTAVADEKPGPYSPFQNTNSWGEYAVARLDDLMNWGRKSSLWPLTFGLACCAVEMMHIAAPRYDMDRFGVVFRASPRQADVIIVAGTLTNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIIPVDIYVPGCPPTAEALMYGILQLQKKIKRMKTLQMWYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBN7</accession>
    <name>A0A1D2MBN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase/reductase SDR family member 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002035">
        <property type="protein sequence ID" value="ODM90321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBN7"/>
    <dbReference type="STRING" id="48709.A0A1D2MBN7"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43115">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43115:SF4">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="8753" checksum="2E649CC25655A1A6" modified="2016-11-30" version="1">MNALADTFVEKKYPGVLVPYKCDVSKDEELEKMFEWIENHHGGVDVCVNNAGFSYDKPLLEITGDEMRAMLDVNVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC76</accession>
    <name>A0A1D2MC76_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_16171</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001928">
        <property type="protein sequence ID" value="ODM90511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC76"/>
    <dbReference type="STRING" id="48709.A0A1D2MC76"/>
    <dbReference type="OMA" id="YQDAGMD"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000013">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM90511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="50104" checksum="132B4440503B03D3" modified="2016-11-30" version="1">MREIVHLQVGQCGNQVATKFWEAIAEEHGVDMDGIYGGTDDRQTDRISVYFTHADGGKYVPRSILVDLEPGTMDSVRSGSMGKLFRPDNFVFGNSGAGNNWAKGHYTEGAEMVDSVLDVIRKEGEACDCLQGFQLTHSLGGGTGSGMGTLLLSKIKEEYPDRILSAFSIIPSPKVSDTVVEPYNACLSFHQLLEHSDEVFCIDNEALYDICFRTLKITNPAYGDLNHLISSTMSGITTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLCAAGSQAYETLTVSELTQQIFNAKNMMTACNPQHGKYLTVAAVFRGKLSMKEVDEQMLTVQNKNSSSFVEWIPNNIKVAVCDIPPKGLKMSATFIGNSTSMQEVFKRITEQFSVMFKRKAFLHWYTGEGMDESEFAEAESDLHDLISEYQQYQEATIDVAEESNLEEEEEGQSQVALVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCT4</accession>
    <name>A0A1D2MCT4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Small conductance calcium-activated potassium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15874</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001787">
        <property type="protein sequence ID" value="ODM90808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCT4"/>
    <dbReference type="STRING" id="48709.A0A1D2MCT4"/>
    <dbReference type="OMA" id="YHINEML"/>
    <dbReference type="OrthoDB" id="73653at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016286">
        <property type="term" value="F:small conductance calcium-activated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000027">
        <property type="entry name" value="Small conductance calcium-activated potassium channel, isoform O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036122">
        <property type="entry name" value="CaM-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015449">
        <property type="entry name" value="K_chnl_Ca-activ_SK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10153">
        <property type="entry name" value="SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03530">
        <property type="entry name" value="SK_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01451">
        <property type="entry name" value="SKCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81327">
        <property type="entry name" value="Small-conductance potassium channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0407">Ion channel</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="3">
        <location>
            <begin position="212"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM90808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="44757" checksum="DE1F4A77A751E923" modified="2016-11-30" version="1">MLRKQKPNVGYRLGRRKALFEKRKRISDYALVMGMIGIGFMVLENELSSANIYDKASFYSTALKTLISVSTLILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRMAQIGLELTVCAIHPVPGKYDFIWTTKMANHGGYLKTEKVPIDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERNHDPDHANLLNSMWLIAITFLCVGYGDIVPNTYCGRGICVACGMMRWVWRYRAEYILWKGNRSNDRHYGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQTNKAGRNYMLRVRNYAALRKSLLFRDYTHAAGDEIEIERCEDASKRVRDSKRPSRSSRPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD83</accession>
    <name>A0A1D2MD83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001737">
        <property type="protein sequence ID" value="ODM90940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD83"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="17267" checksum="D248053E382CF183" modified="2016-11-30" version="1">MLNNCSSISNPSAANTKVFHARFADSEAKIVPVNDRNVGKVLQPWCQGLSVEVTTDAVGIVSVDGTETVAHTDGQSNSHWESTSCPIKFDRDPENKHCKHNYAIRPENVSVAITSASEIVTVAETGIAVSMGGAKIIEVRAQLDNDEQNDDTNFKLKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDH0</accession>
    <name>A0A1D2MDH0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcium-dependent protein kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001695">
        <property type="protein sequence ID" value="ODM91030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDH0"/>
    <dbReference type="OMA" id="DSECCKH"/>
    <dbReference type="OrthoDB" id="8015076at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="15966" checksum="B324D9B5C5FFD763" modified="2016-11-30" version="1">MKVASQCCRINLFTNFCRDGAKGTPCCGVRDCNIFCCNCSEGGCRDGDHTVFKHYWNKLVSHVRGSRYARNIHDNSLSREQDEHEHDKNKDGFYDINEAHNILLSGSCGNYTEKVSHFAEKFNQMDKDNDGKLSYEEING</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEH5</accession>
    <name>A0A1D2MEH5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_15401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FKBP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01001608">
        <property type="protein sequence ID" value="ODM91282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEH5"/>
    <dbReference type="STRING" id="48709.A0A1D2MEH5"/>
    <dbReference type="OMA" id="CEHIDRI"/>
    <dbReference type="OrthoDB" id="8116123at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042282">
        <property type="entry name" value="FKBP6/shu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674:SF1">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="141"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM91282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="428" mass="48211" checksum="A953BF0B84BBE322" modified="2016-11-30" version="1">MDSDDEFVDCEEELEGLSYSNIDVNLSRQLEQNLDFQRMLRGEVQSFDTLGLDMDEIIETEGFQAESKPTPDSALPMYLSDKTTLEKTKFRHGDQTVNEAISTMFGDFDDLEDLMTNVCEGDDRLKKLVMKSGTGASVEAGQLVRVHYVIGCEFMDDIIESTYIKRKPARFRIGGGEVLHILELATATMKIGETSKFLGTSDIGYGKMGVPLDDTKVIPADARVVIQIELLDAKDKVAPQVETISDLSDAERRQIGFEKLFKHAEEMKNEGNDEFKAGMYDRAKLKYKAAIACAKDMDPITAAETQQFLSLRGVLCKNLCMTCYKLGDVKTALKFGKAAATNLDVSKDIRSKSNYWCAKCYYDMGDYHEGVKYIKVARNLCADSNVTELFDMFQKKENELRNKEKDICARMMKITTNETKEAQKGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFH1</accession>
    <name>A0A1D2MFH1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14934</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01001433">
        <property type="protein sequence ID" value="ODM91749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFH1"/>
    <dbReference type="STRING" id="48709.A0A1D2MFH1"/>
    <dbReference type="OMA" id="MIINWYL"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM91749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="38938" checksum="E4F87DF1C5417488" modified="2016-11-30" version="1">MPDFKEYPKNKLSIYIADPRVENWFLMPRWTPILTIIIIYYLVVLIGPILMENRRPYTLRNVLKIYNFVQVMISGYMFKEFVISAWQSSYSLQCQPVDRSNSPQAVRMAAACWWFFFSKVIDLLDTVFFILRKKNSQVTFLHVYHHGSMILNWWLAGKYFPGGQIFFQCTCNSFVHVVMYTYYFLSAFGPAVQKYLWWKRYLTQLQLIQFLAIIVHLIYGMSRTCDFPFVLNCYIIIYCITLISLFTNFYIEAYQHQRTDRLEIQAAIQEKRARSIAAGGTGTNNYANNSYMNNLRNGFIKNSSENGCSGPTMISNGYGTDVNGNGPMAYLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFR2</accession>
    <name>A0A1D2MFR2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001406">
        <property type="protein sequence ID" value="ODM91836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFR2"/>
    <dbReference type="STRING" id="48709.A0A1D2MFR2"/>
    <dbReference type="OMA" id="SIMALHT"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="2">
        <location>
            <begin position="56"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="28122" checksum="DFFC059285EC6170" modified="2016-11-30" version="1">MSLRRSEVTMVNSSWTEGHILQLWQKPETTFKVYPACDVRAFKELVRHDEDQERRSINVVSVAQFRPEKDHQMQIKAMKNPGTGVVAGSGWCCWKREEMNGDRERVDNLKELSRQLGVEQNCIFQVNFSFDTLKKELVDGLMGIHSMWNEHFGISVVECMAAGLLMVAHKSGGPLMDIVVDDEGDRNGFLAADEHEYARVIKSILEMSPELQERIRKRARSSVDRFSDQEFERNFRESLKIVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFW7</accession>
    <name>A0A1D2MFW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Low-density lipoprotein receptor-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_14813</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001392">
        <property type="protein sequence ID" value="ODM91869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFW7"/>
    <dbReference type="STRING" id="48709.A0A1D2MFW7"/>
    <dbReference type="OMA" id="DEINCHK"/>
    <dbReference type="OrthoDB" id="9990982at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042562">
        <property type="term" value="F:hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000002">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF14">
        <property type="entry name" value="MEGALIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903953" evidence="12">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM91869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18114" checksum="FAF894221FAD1200" modified="2016-11-30" version="1">MKAFLVILGLCAVLGFSYSQECAGNEFLCEDGKFCIPNSWVCDGDPDCDDESDENQNCATTVPTGPTTSPCPGFTCLNSGRCIIAEWVCDGDNDCGDSSDEQNCDDVTTTQCPGFICEETGRCIPNQWFCDGHEDCPSGQDERDCPTENPVKPSRKQQRKRPARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFX6</accession>
    <name>A0A1D2MFX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001417">
        <property type="protein sequence ID" value="ODM91792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFX6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="7077" checksum="A95BE2D87F45ED18" modified="2016-11-30" version="1">MLQAVNWSEKLGQIFGGHRGRVLRILILFLCALAVLIGVYRSRSARLEKEKLRREKPLLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH29</accession>
    <name>A0A1D2MH29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Melanoma-associated antigen D2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001281">
        <property type="protein sequence ID" value="ODM92275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH29"/>
    <dbReference type="STRING" id="48709.A0A1D2MH29"/>
    <dbReference type="OrthoDB" id="205198at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="201"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="535" mass="59676" checksum="D7C1E21DBB89F17B" modified="2016-11-30" version="1">MSWRRSTRIHAQAKRPRFQDGTDENVYPSDVHHQASVGDMMMAGGSWQMGHHHLAAAVDSFHNMGMSSYHHQYPHYQTQYHGVQHQPQYQQYHHPVEMSQGMMMPTPTMMGDAEPGTSSGRSLRNRAGPSTSTPIISRGKRIGAPSSQLATAASSSGEPSGSGRVASVLDDAEDDEDDVEGGTASGTPKAKKGGMETSLTVDQMVHNCLYYLLVSQHKKVPVKRSDLIKNAMNSQAKSFSDVIKKLSASLDEVFGMKLVRLEKGKEHLTVASTPTDDEPGDEKEDDKKGKSKGKVDEKKGKGKGKGNSSSVCMYMVVSKFPSSVCDSVMKRDPEVDSKKTVLYLVLSTIFMLNRAIDEDLIWKIIQEMQLDQIVCQRREDLRKFLKSEFVSTGYLNMEVNERDTHPNAPKKARDPSSNDQNDKPEYEQATARYLWGPRAHVEYSKYAMLKFVTNRFPGRRPYEFTVQYNVIKQDEKEKGLLEEIIEERESDNDHASAAAGRNGSALRVKPKTKGKEPAYAIDTGGDNTETETEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH32</accession>
    <name>A0A1D2MH32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flotillin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14394</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001277">
        <property type="protein sequence ID" value="ODM92289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH32"/>
    <dbReference type="STRING" id="48709.A0A1D2MH32"/>
    <dbReference type="OMA" id="THGQGES"/>
    <dbReference type="OrthoDB" id="6080404at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016600">
        <property type="term" value="C:flotillin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002020">
        <property type="term" value="F:protease binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045661">
        <property type="term" value="P:regulation of myoblast differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03399">
        <property type="entry name" value="SPFH_flotillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF46">
        <property type="entry name" value="FLOTILLIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="26"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="15625" checksum="2CF2F27C61C6B36F" modified="2016-11-30" version="1">MNGNQCNVSKVCMCDTHSGCCGATTKRTIVGGWAFAWWFVTDVQRISLEVMTVNPVCEHVETSQGVPLTVTGVAQIKIMRADDLLKTAAEQFLGVPVNQLRSTVNQTLEGHLRAILGLYYLDIQRGWQQKKVQERKELSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHR8</accession>
    <name>A0A1D2MHR8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_14134</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01001203">
        <property type="protein sequence ID" value="ODM92547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHR8"/>
    <dbReference type="STRING" id="48709.A0A1D2MHR8"/>
    <dbReference type="OMA" id="TEYNNIC"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050321">
        <property type="term" value="F:tau-protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000156">
        <property type="entry name" value="Serine/threonine-protein kinase SIK3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057380">
        <property type="entry name" value="UBA_SIK1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF42">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SIK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23312">
        <property type="entry name" value="UBA_SIK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="60"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="496"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="644"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="780"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="794"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM92547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="804" mass="90838" checksum="5F4676D119EDE06B" modified="2016-11-30" version="1">MSEASRVYGVLKILSFPTIPSSSNSNLQQKKKKKSPITSRTQVRMADPRKVETLVRVGYYELEKTIGKGNFAVVKLATHIITNSKVAIKIIDKTKLTPDNLKKIFREIHIMRKLKHPHIIRLYQVMETEQIIYLVTEYASRGEIFDHLVMNGRMHEDEARRIFKQIIDAVSYLHINGIVHRDLKAENLLLDINNNIKLADFGFSNEYQEGSLLNTWCGSPPYAAPELFEGKSYDGPKTDIWSLGVVLYVLVCGALPFDGSTLHSLRNRVVGGKFRIPFFMSNDCEHLIRHMLVVEPSKRLTIQQILAHKWMMQGEPAALPEEPFCMTISEPLVDQIALLPGVSKDTVLQSVRERRFDHISAIYDLLFDAKEEDVRGGPGPPQPLPVFHLPVQRKASITTGVVERQEPPPEIHLLLNDSQIYEKFDEMREVEEELRRQDSTQIQPPQGRRHTVDLPQQGIPVVTHGFDDPAIPLVESVKDQHLLKPPPSMESTCGFGRRASDGGANLQQKEKQQQSCEGGWSHPSSREQLSTGVLRRDATYLATPEEEMLFRGRNRRTGLITVVERPPVVDPESHKLYMSGPNFSYNYPQGQGISMLPPPSHSRRLFHHALSRIQPRKYRTTYYQPPGRETYKELCHVSCERYSPVRRGSEGTCPPSPRLAKTLQQRDDRRHSITSSSPSSPVRLFQPLDSPLAPHPQVPGPLDISQGLQGLHLYSHQTQGPPSPFSLQNNQTLAMIQEHDILKHVDATQTGFAYPEISVTDESGCLPVYLLQDQDACRRPSITRGIGKPPPTTESDKEIPLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHV8</accession>
    <name>A0A1D2MHV8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14094</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001195">
        <property type="protein sequence ID" value="ODM92587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHV8"/>
    <dbReference type="STRING" id="48709.A0A1D2MHV8"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF18">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="79"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM92587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="48769" checksum="43C574E686A7756F" modified="2016-11-30" version="1">MNCTDYTTDEYLPEIFTCQIIDLSEHKLCSEHKPNVCIRCSILGKFFTGESIYETKAIGHVICVFLWSLTVIVGVHGVATNFLIVIITRRINSQRPFDILIMFLAMFDLLCSGSTVVGMTVHVAFYQSWVNKNFWTMHWFHKSTLAILLCRTASTYMAMLITMERFLVLKFPFQTRYWFSTRKTILLAIGVIVVSLILNVPRFLMFEVEPNHFQSANITALHDFTYIVGVTHIFGWNTICFFFENLWDMNEHLDFLAPLPVLLVFNVLSYAKVQKMQNRRKQLDMGVKAEIETVRLFLPVVIAYFSTNVVPFVHFFIAYFTDTFYRELNAAVGLSIAINSAVNFQIYYYQRKAFRMETKAFIPKWYKFVSVFRPNEAMLHRDNTVDTGTETRSTDSALLTNKNTFKSWVNWKAESGVEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIN9</accession>
    <name>A0A1D2MIN9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Limulus clotting factor C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14012</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001177">
        <property type="protein sequence ID" value="ODM92674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIN9"/>
    <dbReference type="STRING" id="48709.A0A1D2MIN9"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904101" evidence="4">
        <location>
            <begin position="18"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="37"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="416"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="613" mass="67247" checksum="8E9B0A36FBD4D4B3" modified="2016-11-30" version="1">MTVQIIILICGCSALYRNPTPDCGHPSVDLLGNSPVVVFGETATRESFPWHAAIFRSNGPGTQYQFYCGGSLITPSNKGFLVVTAAHCVTSSLRTHKVRPLDDFRVVLGSVSSNYKDNEKARGTQIFSVKAAKIHPSYDYNRVQNDIAIVKLNGTVKLSEYISPVCFPSREMANKQITGTGLISGFGLDETSKITKILNYARLPVTQNQICNYALGKELTSVEFCAGYSSGSSVCSGDSGGGLIFMDELTKRLYIQGIASNVDKRTLDEKKYCQNYNTFVRVSSFVDWVQDELDQFFSDVDDSADEQHLRQPGSGSRPTRPNANRPTGNRGEFLVTVYRDINDKSHYEEWRMSNCSAVPQNWNVGQFWVDVHGKCLQFFEGRVCSGRSLQLQPSPSSSVFKWNFPDFYISSVSLCQGGPPSSSGPSQGSQGGSGSSKPIGGPDNGNGQQGGFVPGSGSSNQGSNQESDYQVVGLRRHNAYRLRHGVPQVVLSEALNVKAKAYADKLINYNNLISSNEGGENLFQIRGSSESSAAIVKQAVDLWYDSMKDYNWERPTATSFSQLVWKSTREIGIGVARSRGRTVVVAKYSPPGNVFYGGADPYKYFRDNVYPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIR5</accession>
    <name>A0A1D2MIR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001122">
        <property type="protein sequence ID" value="ODM92898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIR5"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="36024" checksum="339FBF0B863B4C39" modified="2016-11-30" version="1">MSYNAVLRKENAEVFGRMSLSTLETLPGSWDIMFGDNFIPKTTDLKTILCDSKFPLSIHTVPGEREIIVKPDFRGENFEYKFSVSRTTKVRQLKDWIWEKMEMQGKSGLLKGHKMALLLHPDDKDDKILGDNQPIKGHSYGLTVFGTCPRKSCRSNNIPQQQTTYKAGYGFLRIDLKNKNVRCVGCKAPNCKFPPSTLVVCEGRALFRFKKTEGHLDAQTKLLESFGGIDEYASFDVGGGNAEYDWIEVTTVKKDESVYSCSRCNMPIQKWKETVLYGCPLSHPVHRGCKEDQCGICNARDIRTESLTLWSIIQLGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ23</accession>
    <name>A0A1D2MJ23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001120">
        <property type="protein sequence ID" value="ODM92905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ23"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ23"/>
    <dbReference type="OMA" id="HMMENDG"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="6"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="121" mass="13472" checksum="B087C235B09DE3C4" modified="2016-11-30" version="1">MKRLSVLAKKCAEFHMMENDGDRECPYKNGDGEIWLMGTDDWKKSDMAGKAAEKWYKQNENYDFTKPGYSPTTGAFTQLIWKSSEKLGFGFAQMKGKTVAVGIFSPGGNVKGMFPENVAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJP8</accession>
    <name>A0A1D2MJP8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kynurenine formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001096">
        <property type="protein sequence ID" value="ODM93024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJP8"/>
    <dbReference type="STRING" id="48709.A0A1D2MJP8"/>
    <dbReference type="OMA" id="WITIRRM"/>
    <dbReference type="OrthoDB" id="7108654at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118:SF12">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904143" evidence="2">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="262" mass="29445" checksum="625A6C50AFCE4ADE" modified="2016-11-30" version="1">MNPNLIIFVAFAICPVFISSARNPNKFIDLTHAFNNQTMSWPGRKSSWYLETEGFTAGGFWVASKGFCTSEHTSTHIDAPYHFSKEGRKLHELPLEDLIDIPGVMIDIYDKVHKFKDGKLNVIENYALTQDDVIEWEEKNEEKDLEAAAAPTNNTVDDDKTIPLDVNLNFPSFDVSSARYLAVERQVLGVGVDALSIDPGNTKTFPSHRLFASRNIYMLEMVANLHALPPKGFNLWVVPFKIDFGTGAPTRVLARLNNKDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK07</accession>
    <name>A0A1D2MK07_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001006">
        <property type="protein sequence ID" value="ODM93377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK07"/>
    <dbReference type="STRING" id="48709.A0A1D2MK07"/>
    <dbReference type="OMA" id="YESFHYT"/>
    <dbReference type="OrthoDB" id="427071at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039210">
        <property type="entry name" value="OGFOD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14650:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14650">
        <property type="entry name" value="PROLYL HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="6">
        <location>
            <begin position="119"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="328" mass="37274" checksum="AB3A3C9A4C9F24C5" modified="2016-11-30" version="1">MSSEVTQRKGDAVSKSTKEEPKETSGSPSKTKKDKDQAEDAPPKPKFGPMPRFSKQRLWSRGILITGLLVIVWYNSGKKNEQSFADFDEEITAKAMKTRCSSSHEAAVKPFSKCIPKQCGRFVVDNLFSPQEIYALKDLMERVFKEGKVEGAASVFDFQLGLMQLEGETVDLYKLNSTRKIFQKGDQIIYQNLKGKLQRLISSYFAIDHWSLHTAAPMFMTRLNRKFAKRESDEYWHPAVHQKQFKTYQYSTVLFMSDYGTDIEGGRLIFIDGDNTNRTVDPKLGRAIAFSSGEESLHYTERVRKGTRFAVTVGFTCNPNDAVLDPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML34</accession>
    <name>A0A1D2ML34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 4C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_12940</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000926">
        <property type="protein sequence ID" value="ODM93736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML34"/>
    <dbReference type="STRING" id="48709.A0A1D2ML34"/>
    <dbReference type="OMA" id="MWPENID"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM93736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="537" mass="62570" checksum="956FE0E4275A6B04" modified="2016-11-30" version="1">MTNHRKTWKYSTEQLLKMETYSHYFFHILSFSGKSVLQNFLLISTISLFLLKVVQRWAGFWSKSLEEDPYKAYKALRGPRTLSPTGNVLWFILKNDLLQKFVDYALKYGPIYRLDFFFEEVICLTSPEATQALLSSQNYGHYRHGQLQELMWPENIDSLLVLPGGEKWKSRRKLLSSPFKYKALQVHNPCFHKHANRLVQQLETRFKDGAGSEGILSDLLTVCTFGISSETLLGVDLDETEVGAGTLFCKNVNIFYKNVIGRCTRPWLLIPWIWKRSSAYQETTEAIASMRRIAGKVIEKYKHKMENDSRTDSEPNDTMIEVMLRKGADEKLIFDEVTIMLTVANDTTPISTEYALFILALHPEHQERCRQEIDKVFNDPNMFKDGVLKFEALTELKYLERCIQETLRMNPIVMIMRRLEAPLRINEELMGFPCSYRPIAVHNQPQYYPDPEKFDPDRFLPEKVRERSVYGYIPFSVGQRSCIGMKLAILELKIMIATILRNFEVRTPERREDVKLVVVGITKPSKPIRFILTRRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLN3</accession>
    <name>A0A1D2MLN3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein SPT2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12846</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000904">
        <property type="protein sequence ID" value="ODM93838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLN3"/>
    <dbReference type="STRING" id="48709.A0A1D2MLN3"/>
    <dbReference type="OMA" id="GPMATPH"/>
    <dbReference type="OrthoDB" id="6259853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054552">
        <property type="entry name" value="SPT2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691:SF8">
        <property type="entry name" value="PROTEIN SPT2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691">
        <property type="entry name" value="YEAST SPT2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22878">
        <property type="entry name" value="SPT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPT2 homolog N-terminal" evidence="5">
        <location>
            <begin position="16"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="223"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="324"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="401"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="494"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="539"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="677"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM93838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="687" mass="79102" checksum="B0CB1D6A47C24003" modified="2016-11-30" version="1">MGGVQVANQALYDPNKPRRVDPKEVRLKEGVAKFLAKREEEDRKKRDEERVKKEKLLQLRNQDRKAANRPDEDDYGYTSNYADMMHKKMMEKYKAIPVKPAFPQERGPPIPKPQTFSKNNGSGWRKSNTDNQGDYSPEPVYEPEPAAAPSKPAKPSRVPKPKPVDYQQLLELAKLKALEPALPTKVVVDKNAEREQYEFGRPMTAKEKAAFLAEKELKDKVARRMDFRADKNNNGATDPKSTKDQSFKIPKARQRDEDVTPAKKPRISESGDGKLLHRELSKSRPAEPSSHAARSSSPVRKPLEKPYRQSESAKPRERDPYRGNGQSRPDSRPQGNPDRQSGERSRGPPSKDRVNVDQNRKPASPSGFKQKPGPSRESLQSGLSDSRENARMGMSSMKNNPQRDSDRRPIKKDAPPVRRDDVQNRREPAAPRRDDSQQRRDDSQQRREAPTARRDESQYRKETPASRREEVSYRKDTQQSRRDGPPSGRSEMQPQRRDVPTQRRDMPPQRRDNIPPQRKDNLPPVRREMPPLGRGDMGPPRRDAPVAGKRDAPPPRRDGPPPARRDGPMRGSDRMRDEQRRMKPRPPKGRAVIDSDEEYDSEMDDFIDDSELDTGNISAIIGQMFNYDRRKYVYEDSDDECMESSVAQQMREEQRSLRIGIQEDMEDIRREEEEKRRKMGKVKKAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLR7</accession>
    <name>A0A1D2MLR7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger MYM-type protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000885">
        <property type="protein sequence ID" value="ODM93947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLR7"/>
    <dbReference type="STRING" id="48709.A0A1D2MLR7"/>
    <dbReference type="OMA" id="DILCHEA"/>
    <dbReference type="OrthoDB" id="7692318at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025398">
        <property type="entry name" value="DUF4371"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006580">
        <property type="entry name" value="Znf_TTF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45749">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45749:SF21">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14291">
        <property type="entry name" value="DUF4371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00597">
        <property type="entry name" value="ZnF_TTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TTF-type" evidence="2">
        <location>
            <begin position="146"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="486" mass="54682" checksum="DCDE50A0CEC3892D" modified="2016-11-30" version="1">MAKRKQTFLDNFLSKKTSSSSSDSSLHSELSVTAKPGGSGLQTSSIPQEIGREENTAHSLEPANAPKVDLSSSNVIELNPDVLGIPPNNDQDPEEKVDDRQTTKKLETSTENLSQSTLAPESASQIVSENAYQPSDWASVQHVGKRHFNFQQSWFQTFPWLHLDKDIQKMLCIICVNATRLGLHRANTVKEETFLSTGFCNWKKAIDKCKKHESSNYHTTSLNKLAELRNVPITQKLQTEALKLQATARIFLRKIITSILYLGKQGLGLRGNESDSGNFLALMELRSEDVDGLSAWLHRSKSFTSWAIQNEVLRIASHSLLRQVMKKIENAKYYSVIVDETTDSSVKEQVSLNIRIVDEDFEPQEYFMGLYETEDTTGNALFTRITDALQRFNLSIENLRGQCYDGAANMSGKFKGVKAKILERQPKAFFVHCFNHSLNLALQDSSKSIAFFRDILCHEAGILVRASPKQIEHAWRVGGRREPIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLS6</accession>
    <name>A0A1D2MLS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000877">
        <property type="protein sequence ID" value="ODM93980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLS6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="111" mass="12514" checksum="2A24C632C979AE71" modified="2016-11-30" version="1">MFDISPASPPSRPEDSDNIFTTPSSCNTKLTKRFATLLPSLISCRHQRISLHTPPSRSESGARQRRSQARKQGSQTRRKRLNFNSGNGDESDASVIGPHLLSKLRRHYRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMU6</accession>
    <name>A0A1D2MMU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ras GTPase-activating protein-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Stress granule</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000852">
        <property type="protein sequence ID" value="ODM94144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMU6"/>
    <dbReference type="STRING" id="48709.A0A1D2MMU6"/>
    <dbReference type="OMA" id="RPRGNAY"/>
    <dbReference type="OrthoDB" id="339151at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000015">
        <property type="entry name" value="Ras GTPase-activating protein-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="6">
        <location>
            <begin position="30"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="438"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="186"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="247"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="513"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="598" mass="64593" checksum="511D446B8A722D48" modified="2016-11-30" version="1">MVMEESNIHHHSPAGENNNANNTNNNVYLVGLEFVRQYYTVLNQGPLYLHRFYSDDSSFVHGVSARDSKVAYGQQEIHKRIQSLNFHNCHAKIRQVDSHETLGNGVVIQVTGELSNNGQPMRRFMQTFVLAPQNPKRYYVRNDIFHYQDEIFCDDEGEPDTPPESTPVDTEEAEELDKEGDINGGSEIIAADPTSPVSTTVTVPKLSSGGITPPTVSATGNSPNNLVEVAVEEKVQIKPVVDIPALSSNQQSGAGDEDSVVSVKPPAVTVPAPEEEQQQQPANNTSNSGPKTYANLFKGHGSSSSSVSKPNKLPTEFKPTAGVNKHAGIGSNGPSGGSPGNSQVTVSVNDGGVTSPPQVSPLPSSTGIHKGLPPRNPPRNQAYNRDRGGDRDRPGGDRDGYQNRRERLISRSSTTLNDETGSVDGDRRRPVNTYPDANQLFVGNLPHFVTPQDMKDIFSEFGEVAEVKIQKPMPKSTGVKVPYFCFVVFEEAVSAQSAIEKKGEIFMKLNGGAQRRLNVEPKRSQRSGRGGDDSDAPYNRMDAASPAGNRPSDGMRSQSRTFRGSNRSGGMSGDRDRGRGGLSDRGRSERGGGGRGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNL5</accession>
    <name>A0A1D2MNL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Unconventional myosin-Vb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12236</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000803">
        <property type="protein sequence ID" value="ODM94444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNL5"/>
    <dbReference type="STRING" id="48709.A0A1D2MNL5"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058662">
        <property type="entry name" value="Myo5a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046987">
        <property type="entry name" value="Myo9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46184:SF5">
        <property type="entry name" value="UNCONVENTIONAL MYOSIN-IXA-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46184">
        <property type="entry name" value="UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25966">
        <property type="entry name" value="Myo5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Unconventional myosin-Va/b" evidence="5">
        <location>
            <begin position="442"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="404"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="623"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="259"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="623"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="640"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="741" mass="86304" checksum="E0E34A6D0C997850" modified="2016-11-30" version="1">MSTSSRKKTVGSQFRDSLTPHAKFKCPRRLTMFVVLNQTTLKRHLSLTHHRLYRPLVKNSKDINRQSPRATCETIVYGMISDEDAYRFGKSKIFFRAGQVAFLKIRMEKLQIQCSYDSKNVRGFIYKARYTKLKKSVQKLQNYGRGMLARRLALKLRQTRAAIRIQTCFRRWKKQKEYQRLRNITIQFQCRIRGCLARKKAQRLRMIKAAIIIQKYMRMWLEKLRFEKARQDIIKVQSCVRRWMAKRRLKELKTEARSLEHVRQLNKGLENKIISLQQKIEEFSKGANQNKKVVKDYEKIKVQLDNYKHMEKDLKAALEKIGELEGLNDGLEDELRGKMDARGGFVTTKVELGARMEDYGLQMGGWSEREKWSNRPINSCSKKCMTWNKILSLVVDIKDRRTTPVPRKSLAPNSLDSGLPSLDRSPSPTRRALQIGSPNQIQQNASEPDIGLVLVLQQKLRQSEKERESLEKQLEEQSATNPDSETRRTQDLIRLQELEMENAKLRDDLNHLRSADDKDTEISRQFQSLQEELARKKEESIQLRTLLASPNSWSGNSKQKRWRNTISFPKTKLWKTKSKSRAWLSVSPSTASVWQGWRSSPKHEVGGLTNENLTLRDHLSRLKTELESDTSEQRSHRNLKQSNDSMTAQQSELGPCVHPKEGPGLLGYAGVSTRRRGQDYASSILDSNHNCSFPLSKRSSQPYIPMFHEIRYNRFTSTDDNKVRSLLTSAITYIKRLMRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNU6</accession>
    <name>A0A1D2MNU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000794">
        <property type="protein sequence ID" value="ODM94524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNU6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="243" mass="27420" checksum="9ACE9CB95894E736" modified="2016-11-30" version="1">MNKSRKTSYEEAQELPTNCGVDFDGECQTWDGLFPEDPEEEFLGECEEDDEECFQRLLDEEEQYDTTSTNMAVRGSQSTKKNSLRSTQKSFDRNGSLPGAGQDPEDVYKNRMFPEMENEPFEGLPENYYKKKYRPDYPTDLRMKPVCAAKPARRRTVGTTKTQIHAYFTPSDSSFLKPEQDDRSAAGTAKKRGTGGASSLRTSMTKGDTVGISNLPFDETSPLEQNRMPPPIVSSSDEVIVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPH0</accession>
    <name>A0A1D2MPH0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxygen-dependent choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000748">
        <property type="protein sequence ID" value="ODM94802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPH0"/>
    <dbReference type="STRING" id="48709.A0A1D2MPH0"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="22324" checksum="8ED2057C83FCB912" modified="2016-11-30" version="1">MVKVLTKIRYHVKSGFRHGFKNVIFSKFFFGFVASLGMLIASHDKAGRIRDNLNARLNDQEDTFDFIVVGAGTAGSLLANRLSEQHKVLLLEAGGEPHPSNAYPPWPSSWSTTERLTGCIAPCPKDELASLLPADELGSPKDEIWGAQGTSTTSCTCAAPRVTMTTGLNSRGMRAGRMKPFCTTSVGTKTTREIHQTGKHTALMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ19</accession>
    <name>A0A1D2MQ19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer dense fiber protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000707">
        <property type="protein sequence ID" value="ODM95133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ19"/>
    <dbReference type="OMA" id="RAPKYSM"/>
    <dbReference type="OrthoDB" id="406368at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051291">
        <property type="entry name" value="CIMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580:SF28">
        <property type="entry name" value="BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580">
        <property type="entry name" value="SHIPPO-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="25047" checksum="59BA7A4F88C8132A" modified="2016-11-30" version="1">MGGHIQQRPWTPTKRRGPIAAEFSSPGPASVALPGLIDRHVDTTDHAGPGPGTYNVMGLSSKGFTDSGKASAPSASLHYRHAQPKAFVTPSPGAYNPETSEKIILDHSPKYSFGTKTEKKLKSNTPAPNAYNVPSVLGSNQEGTMQKAPSYSISGRGKDAIDPRVANPGPGKYEAGSMDAMKQKAPAFSLSTRTQLPSDDTKKPGPGAYSAEKVNLNLAPAHSFGIKHSPYIISKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQS8</accession>
    <name>A0A1D2MQS8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Palmitoyltransferase ZDHHC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000677">
        <property type="protein sequence ID" value="ODM95413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQS8"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="14613" checksum="76FAA150537DD861" modified="2016-11-30" version="1">MLLCDHHCPWEPIVSCFTTTKFFILFLAYAFPVLRRDLCNFISILYRLLRGGWDAPMQGRFHILFVFVCRCHVCDKALCSLCGVYSLLSLAILVTRNRVPRLSHPSLPYSETRRRQERIQSWNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRL7</accession>
    <name>A0A1D2MRL7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000657">
        <property type="protein sequence ID" value="ODM95538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRL7"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904432" description="Chitin-binding type-2 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="37799" checksum="B7F6DC5B1BB85FF8" modified="2016-11-30" version="1">MYTCACIILGILFSLGEYCNAQQNRRPGSTSAGMDAYRMRLAAYNRRQSTPKPAPLQTPSAGPSRAGQQAQIVNGFYCAKIHTFFTTEDNPRMYHLCARNRDSWYVYHFFCPGGSIFDESVKKCSMSRRAPPSRPFIVSTPGTSTTTTRTPVIQRRTTTMSTRGPPPNTGFASFLGLNGFFPRPPSTTMASTMMTTTTTTTAEIPEAVPEPEPNATDISASSEESTEEETMGVKNVYVNIPGFTMSSSSSAHPPPADDGNEEATTEIDTPNEEESNMIPESGTTLQNSLAYQLQQVASMHNKTNPSKTMEMVASILKASALSSSGGRRPRVKKQNKWHYYRFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRP4</accession>
    <name>A0A1D2MRP4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">WD repeat-containing protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11111</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000652">
        <property type="protein sequence ID" value="ODM95568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRP4"/>
    <dbReference type="STRING" id="48709.A0A1D2MRP4"/>
    <dbReference type="OMA" id="VIFQWSF"/>
    <dbReference type="OrthoDB" id="10250638at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057855">
        <property type="entry name" value="Beta-prop_WDR19_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056157">
        <property type="entry name" value="TPR_IFT80_172_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040379">
        <property type="entry name" value="WDR19/dyf-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056170">
        <property type="entry name" value="Znf_IFT121-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920">
        <property type="entry name" value="OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920:SF0">
        <property type="entry name" value="WD REPEAT DOMAIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23389">
        <property type="entry name" value="Beta-prop_WDR19_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23387">
        <property type="entry name" value="TPR_IFT80_172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23145">
        <property type="entry name" value="Zf_2nd_IFT121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR19 first beta-propeller" evidence="12">
        <location>
            <begin position="27"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="IFT80/172/WDR35 TPR" evidence="11">
        <location>
            <begin position="539"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="13">
        <location>
            <begin position="724"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="domain" description="IFT121-like zinc finger" evidence="10">
        <location>
            <begin position="1165"/>
            <end position="1210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1232" mass="138601" checksum="32441F786ABD4E6A" modified="2016-11-30" version="1">MRFIMATGSACKRIFTVRNERGTSTMVHCAWQKCPGGLLASSVEGSPSVRIHERQGKIIEKLAVPASCVGLAWDEDGDILAIIVDQPGVLLLWEVHSSRLQEVDTGMKDIGSCVAWSKAGKILCFASQKGNILIYNHRNLRRIPIIGKHSKRIVCVQWSNDTLLALGTIDNFLSVNTMDGDTIKNFQLRGKPSDLQFGQIKEDRNATTVDNTVSAIVGEKTLYLLKFDDGQGALTPMELGFQARYGNLCAHHWHGDGYILVTFSAGFIVLLSSHYKEIGTELVLCELKADPLRHSCLNTKLSRIEGDGMDMRGMKTFPEQSARSFKITCLSMTKDVFLYGGENGVVRIFHMDSWCEIIQLQSPAGVTLKSIHPNFNGIYFIMIDKNCQGFFYNIDEDMMKPVPNFPTRVDGVLWDTEYGSRHIFLAYSLSSTKIQVYVTWRQVLLGEPLHQVGTFQWFQTSEHRPLCFRKGVIASLTSSGRVIRTQCVYLDKPEASDGNELPDGKLSKLTRLLVMKKFADAYDYCLVSKDEEMYLALGRACLESMELEIAMKAYVAVKDIGMVYSIRRAMKNKDYNQCCGNVGVILGEFDLAEQKYLEAGLRIPALQMRRDLQEWDKALEMAQKFAPHLVADVSREYALYHEHNGDFAVALTLFEEAFNKFGDVKRAPPRPMTSGGRAISSQLTDGRVLKQIEEGIARNSIRCGHIQKGFQMAMDSKSAQHKKDCAAVLEISKSYAEAGALYEDCSLWENAASCYIRMKNWSRVADLLQYVQSPKIFVQFGKAKETEGKLREAAVSYEKANDVMNSIRLYLSADYPDDAIRVARVSGSLSGAMLVSRYFEEHGDMETALRFLIISRCYEDALLVAFKHGKSETYVQCIQDEFSAIPSEFLDGIRQVAAYFEEKKDNFKAGKYYQVCGDYKKSFALLMKSAQNRVTVDDNELMEVVIQTVIKSENEAYSRTLVEFLLGEKDGVPKDPKFLLSYYISANKLVEASKTALIVAMEDQKGGNYRDAHATLVRTCKELKSHSMKIPKDIMDALRILHYYLLVRKHVNIQNHKQAARLLVVLVDNISKFPTHAVQLLTTAAVECQKAGLRQSSMQCCFTLMKPDYRKQIADKFKSKIETMVRKSGKAKLEDAPDDLSPCPYCQAMVPDYNLVCTECKSEIPFCIASGRHIFSGDFTTCPTCEFPAVRSEILKLLENEPLCPLCNESLVMSDVNLINDLHPYLFVIRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS39</accession>
    <name>A0A1D2MS39_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein sleepless</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000630">
        <property type="protein sequence ID" value="ODM95718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS39"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904462" description="Protein sleepless" evidence="1">
        <location>
            <begin position="30"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17002" checksum="BB7A79771F096CFD" modified="2016-11-30" version="1">MSFLASHHLFFTLFVTTVLLGISLKSTQGILCWHCTSPKNDSLCDKEHNGENENCNTTLNAMCVIRIRTEKDTKKKEIYKFCESTMDKTSGTCEEEPGTIATTNEVCYCNDKDLCNKEEIAGKGKSGSALITPMIISIFSGIICMLNADLWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTS7</accession>
    <name>A0A1D2MTS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000536">
        <property type="protein sequence ID" value="ODM96477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTS7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904520" evidence="2">
        <location>
            <begin position="23"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="446" mass="48179" checksum="30336C00BF54A633" modified="2016-11-30" version="1">MAKLRRILIFAIFVQIHPQITSRTTIDLNFFQSRNPPDVNSSLTVTTAIPSIPQRIHASLNNVLRIPLPIWGTSTSSRGTIFIPTLPLKPVAQTPTGGAQQNHAVGASGASQAAPTNFLPLPEGIQAIHSTIAQLSTLTHWPFAYVTTTRPAAPSTGNATSGQIEKTTAAPAITVQTATTTTVAPTIPPNTTPLPSTAVKVTQPPPPLPTFLAPPSPIFPQQIIPQLPPRPPLQSIPNRLQNRLQSTLGSYIRLPNLSQIGQPPRSMITEPPWVTELLGPTLEPPTTRAPTLGERVHNTLNNVLLFVPATLLNIWYQNFGHAHVDRIIQRLQVPTPKPGSTDPVFATISQNNALANFTGSESGELPVIAAFLNANGTLMPTVVHPVVNITKNTIEYQLRSENNETTVLWTGSLSNDIFFGNRTALGQEEEDDEDEQIKIGALTLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTU4</accession>
    <name>A0A1D2MTU4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SID1 transmembrane family member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10358</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SID1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000552">
        <property type="protein sequence ID" value="ODM96321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTU4"/>
    <dbReference type="STRING" id="48709.A0A1D2MTU4"/>
    <dbReference type="OMA" id="WAKTICI"/>
    <dbReference type="OrthoDB" id="416618at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051033">
        <property type="term" value="F:RNA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025958">
        <property type="entry name" value="SID1_TM_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12185:SF14">
        <property type="entry name" value="CHOLESTEROL UPTAKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12185">
        <property type="entry name" value="SID1 TRANSMEMBRANE FAMILY MEMEBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13965">
        <property type="entry name" value="SID-1_RNA_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904524" evidence="10">
        <location>
            <begin position="17"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="592"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="651"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="708"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="772"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="825"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="859" mass="98123" checksum="3A0A65224EA9C70D" modified="2016-11-30" version="1">MLFLFVFVYIPECVCGPELLIETKCTIIVANTNQIYQNFVSLEKPVAYVFFVPRRYIQRSHTTNLRIEVSTNEDTSLKYPLLFSARQQRFLSSFEVPFQFDEDQTQITGRSKKNIFYSAGRTLCIDADDEIVEGRNVTLRVSTQSKKLHSFTVILKLTEDYQLPVDKQVEIDVSPTAPKYYGFNFGKPDLDVVKIRAISDSTNCMTISVQTPQCPIYDLEHNVRYKGKWQTMSTTAAMTVLKYGEFAKGFVVVLVAHTDNEECGRRDSSSASYNNTDNWRNSNNLLSTSIKDSRTKTIKLIITDESKVSEWIILACLFIPIFATLLTSLVVIALFRNRHQWLGQTTRENFGTGNASVTLLTSLNDTSNSEQNGTAINNENETRPLNRSSVRPSSVIQRSIPLPSASSQGKFKWKSDLYIADFGCKGYYEVKKFAKRFYWTIGIVAIFYSIPVYQLVLHYLRVLYRTGEYDICYYNYLCAQRLGVLIDFNHFWSNASYVIFGIFFIFIVRRRSRNLCLDELEKEDAESRGKPSCCCCSPGKVGQACLCTFSRICFRWDHGVPAHFGVFYALGVALTMEGFLSAAYHLCPNQSTFQFDTCFMYVIAVLLLLKIYQFRHPVHFGANHTFAILAGFVIVSVLGLLFERGTDNAKLIFKCIFLPFQYTIMIFLSVYYYAVGYVRDENNELVTDWRIYQYLGQLKYHRINGDRIILPFISFSICIAVLVYSELSSMGFASYLLYILVGNVLGTTLYYVGIMKPLHGEFKNRTWVQPTLYFLAAGVIGGFSLQYFVRAPAQWELSASASRAENEDCLSGWFPFHPFYDSHDAWHFLSAAALFLAFMGLLIVDDDLITTKQSSIPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU09</accession>
    <name>A0A1D2MU09_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000544">
        <property type="protein sequence ID" value="ODM96391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU09"/>
    <dbReference type="OMA" id="KKECHTE"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904553" evidence="3">
        <location>
            <begin position="18"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="20456" checksum="3A157BEEC76BF3E0" modified="2016-11-30" version="1">MKSFIVALALFAAVVIASEEEGHRHHHHHHHHHHHHHGGHGHKHLKCKGEAVVRNEAFEKSMEECRKEIKNHEDDEETEGRKSGKACQAVCAMTKVGAFNEEGLIVESKLREMVNEGFVNQEARKELEKEFTFCGRNSTGLGTAHSDHKCSNYKHYFYCIKTAIDTTCVDKSAHDPEDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU47</accession>
    <name>A0A1D2MU47_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium-independent sulfate anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_10107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000525">
        <property type="protein sequence ID" value="ODM96573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU47"/>
    <dbReference type="STRING" id="48709.A0A1D2MU47"/>
    <dbReference type="OMA" id="CCLMGYL"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="SLC26A/SulP transporter" evidence="7">
        <location>
            <begin position="90"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="524"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM96573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="671" mass="73286" checksum="11E98F40D9BFD412" modified="2016-11-30" version="1">MKTELLHSYSSASLAAIARSDSSLTLSQFEYDQNPGGPTATFQTGDDPPSKCEAIGNCVKDWWGKACRRKTLEKKFPIIRWLPKYDTEKLVADIVAGFTVGLTILPQGLAYATVGGLPPQYGLYSGFVGCFVYILLGGTGEVTVGPTAVMAIITFTYTHGKPPAYAVILCFLTGIVTLLMGVFQLGFIVNFISAPVNSAFTSAAAITICATQIKGLFGLKFAAEGFLPTVKGATAHITEVKFWDSILSLICIAALLFLMKLQLIFSFLIKRVPILNKPLWFISTARNAIIVIVCTAIASGIGETQPFTIVGKIVPGLPDFTIPPFTIIDPATNVTHSFTNILEEEASAVIVMPLLAIMEHITIAKAFAGENTIDASQEMMSIGVSNIIGAFFSSMPVTGSFSRTTVNAMSGAKSPLGGLITGTIVILALRFLTPYFYYIPKASLAAVIVCAVAFTIDIDIIKPMWRSKRFDVIPWVLTFLVSLFVGLEFGMLTGFLISVIYLLYYAARPGVKVKKGYSTSGKEFLLVEMDRSLTFPSVEYIRYVISKASQVWGQNKLPVVINCLHIQFADYTAAVGIKEVIGLFKKRDQQIILWQVKPSIVRVLSGVLNEPGRDEYVHFCRSEEEVESIIDGRCTLERKVATLQTMDMDSGVDVHTPHPTHREKYNSIPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUL8</accession>
    <name>A0A1D2MUL8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ribonuclease P/MRP protein subunit POP5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10281</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000543">
        <property type="protein sequence ID" value="ODM96395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUL8"/>
    <dbReference type="STRING" id="48709.A0A1D2MUL8"/>
    <dbReference type="OMA" id="HCFLFIR"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="entry name" value="Ribonuclease P, Pop5 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016819">
        <property type="entry name" value="RNase_P/MRP_POP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48414">
        <property type="entry name" value="POP5 HOMOLOG, RIBONUCLEASE P_MRP SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48414:SF1">
        <property type="entry name" value="POP5 HOMOLOG, RIBONUCLEASE P_MRP SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023803">
        <property type="entry name" value="Ribonuclease_P_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR023803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="17658" checksum="B4F96045BDEAA33C" modified="2016-11-30" version="1">MVRLRHRYLVTEYSVTDGRDSEADNAAIRSSSVLEALTNSIRRLHGVHGVAVSKAGLLVKYINNSTQILFIRMRRSACSLVSSAIPFIRQVDGKSVTFRTIYTGATINHCNKFLVKYQRKILQEQYGSLKTDLQRQYFQRDLDKLKPYSVQLGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUP3</accession>
    <name>A0A1D2MUP3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein beta chain, ciliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUP3"/>
    <dbReference type="STRING" id="48709.A0A1D2MUP3"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46961">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46961:SF20">
        <property type="entry name" value="LOW QUALITY PROTEIN: DYNEIN BETA CHAIN, CILIARY-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="1">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="14326" checksum="BF76A2CE864720C9" modified="2016-11-30" version="1">MPEVDTYGTVQPHTLIRTTYGLRTLRHFAVSRWLSGMDALQNIYKNILQQHLSKSAASFLPTAVKFHYVFNLRDLSNIFQGLIIQHVDCLQHPLTWSACGCMKHPEYTEISLSMTRTSKHFINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUQ8</accession>
    <name>A0A1D2MUQ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter G family member 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09855</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000500">
        <property type="protein sequence ID" value="ODM96829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUQ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MUQ8"/>
    <dbReference type="OMA" id="STINFHM"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051449">
        <property type="entry name" value="ABC-2_transporter_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047817">
        <property type="entry name" value="ABC2_TM_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30294">
        <property type="entry name" value="MEMBRANE COMPONENT OF ABC TRANSPORTER YHHJ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30294:SF38">
        <property type="entry name" value="TRANSPORT PERMEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="607"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-2" evidence="10">
        <location>
            <begin position="404"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="635" mass="71327" checksum="BF40B64F1E95DAC4" modified="2016-11-30" version="1">MRDIALYEYLTIKEILQYFGRIFGMTTSEIDGQTEFLVNFLQLPNRNKQINTLSGGQARRSSLAASLIHDPQLLILDEPTIGLMRNGRLLAEKAPETLLKEHNAHLLEDIVLKLCRNDLSPSLDSHKNSNGNGNGNSNGNGNNNNNGKNGKRNDLVAEALSEISFYSRINKMLPLSRFYKQETSQDKPEVVGLKFQQTVPIGDAEPMRKRHSSIKRRQSFIDTLSDDMWFRVSRIRALTVRNYLNFFRNPVFVLGVVFLPSVQMILTSLIVGQDPQHMRFGVANHEFPDWEDRCSKDLSSNVCGAELSCRYLNQLKYQNGDFFDLVPVEKESDAVDEVRLGKMWGYISFPDNYSDYVGYRSAHGLYADNETLENSIVKLRLDMSHYLAGVFMINNLFRSFQEYLKGSITTCGGNPMEVELPFNYSAVYGSVDSRYMEYIIPGALILIIYLITLCSCAVSVIGDRKQGTLDRSRVAGIQTFDIMISYFITEGTTVLFQAALGASILILGFNLEVQGSTALFLLVCIITGLCGQASGLLIGILCPDEVEALFLGMFFYLPMMLLAGVIWPLEAMPVALRYFSYCLPLTLTCESLRSITSRGLGLLHPKVWPGVAVVSTWTVAFWIIALCIFRSLKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUW8</accession>
    <name>A0A1D2MUW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation-dependent mannose-6-phosphate receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_09810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000494">
        <property type="protein sequence ID" value="ODM96877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUW8"/>
    <dbReference type="OMA" id="MKEMARN"/>
    <dbReference type="OrthoDB" id="29460at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018939">
        <property type="entry name" value="Autophagy-rel_prot_27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF0">
        <property type="entry name" value="MANNOSE 6-PHOSPHATE RECEPTOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09451">
        <property type="entry name" value="ATG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10433" checksum="A62356028F842EFD" modified="2016-11-30" version="1">MSTLFQNITTPAPAPSPKVVDDGMSGGTAFCLFFFIICCVYFGGGILVRKFARGAEGNEMLPHYEFWSDLPNLIRDGVMFTLNGCQPELTYERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVG5</accession>
    <name>A0A1D2MVG5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger and BTB domain-containing protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000513">
        <property type="protein sequence ID" value="ODM96675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVG5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="427" mass="47685" checksum="672462CD800D6521" modified="2016-11-30" version="1">MESYVTRREFENVIKEVRRLQYFLADTFGPKFMEFFKDDKFGEVESTLKNDLGNESTNVLNASLTGVLSKSSSLPSGGGGPMENINKVPPPPSVSPPAVSVATRPSARLILQDASTREYAQKMVRNAAVDEVIRNRPSSSQHSTTTAPVVPISVVKSLKRKLPPGENHEETRSSSPSPQMTERNMLSDDDVKVELVDLDADNDEINKEVHDEPMAPPKPAFLHPMPPTAPLPSFRHSKFQSKLKKPDSGEIIQCPQCHLYIYSNQMDEHLKTHSILNGNGKKPSEKPSSSINLFSKSPLTCFLCKTEFPTFQFYEGHCNLHHRDGNPCPICFKVLRPHGKLRKHMDEHENPKLKKTFRTKKTHPPPQQTSSAATTTMTGSEFGEVDKDQDNGHEGGDNIVGELIEVKMDVGDTVQFEYEGDDDDELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW11</accession>
    <name>A0A1D2MW11_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000458">
        <property type="protein sequence ID" value="ODM97263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW11"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="224" mass="24922" checksum="C0840B29AE98C282" modified="2016-11-30" version="1">MGGRVGKYNIQPTGQGYCCMNSSGRLSRKSGYNMAQFSINFVLATTLVVTCNAFLLFDTPAKLEPKNTRVLEHQASGKCLTVSEEFVLFLDDCSWNKGRQEVASVFSVIKSNTGGHLLRWASGPKPQGIQGCLADRVESEFGEVLSQRPQLVGCDARARTQSWSFQKIADAQYLIRRVGDDGQCLSMSGHDNEDYPRTVKCNSQDPEQLWRICENLSNLHKCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW33</accession>
    <name>A0A1D2MW33_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein artemis</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">DNA cross-link repair 1C protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_09679</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000479">
        <property type="protein sequence ID" value="ODM97014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW33"/>
    <dbReference type="STRING" id="48709.A0A1D2MW33"/>
    <dbReference type="OMA" id="PANHCAG"/>
    <dbReference type="OrthoDB" id="262529at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF8">
        <property type="entry name" value="PROTEIN ARTEMIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="14">
        <location>
            <begin position="25"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="402"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM97014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="474" mass="53753" checksum="26C816D5A9484400" modified="2016-11-30" version="1">MASLVRFHYGENNINTGPLKQIPEICVDHFFGDDLNSSVFFLSHAHTDHLVGLETNEFVRRLNQPGVQLYCHPITPILLGSFERYLGGPQGIEKLVAQRKIIPVDASVPFKIRIPRVPVALEVTVTLLPAGHCPGSVMFLFETSKFRILHTGDFRLTLDDLKTMSQLHAEKDKPKPLDHLYVDTTFCSHSANLFPNRKEVLYEAIEHLRNWISLSDMHIVHISFSAKFAHEYILLELHKTLNQKIHVTPERRAIYQHIPDVYNCVTLNNQTQLHLCGDKACVENGNAITWRLSSMWYTSRAKADRRNVSWNGKTVMLCYSMHSSLEEIAQTIDYLKPRIVTPLVLPIKSQVSEIHEAIKSYTTHEFRFEDYRSTRDVFGDGDVPDAPCPIEQDATDIGDAMDVDEDDADETDTNTASQSTVEGSPEPKRKKLDEDSKLIWQFKFSPSPRSKSSQGSSDDSQNANNSQELDSDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW34</accession>
    <name>A0A1D2MW34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">GATA-binding factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09792</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000493">
        <property type="protein sequence ID" value="ODM96885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW34"/>
    <dbReference type="STRING" id="48709.A0A1D2MW34"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000001">
        <property type="entry name" value="GATA transcription factor (GATAd)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000032">
        <property type="entry name" value="Transcription factor GATA-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF337">
        <property type="entry name" value="GATA-BINDING FACTOR A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="13">
        <location>
            <begin position="98"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="13">
        <location>
            <begin position="152"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="197"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM96885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="32584" checksum="FB9661D8DF51C13C" modified="2016-11-30" version="1">MKMSSGFCATPNFSATALNHHPHQIAAAAAAHAAHHPASLHHNGGLSNSSATAGHGHGHMSMSNLAGSATSPAVALTAAAAVLDTTCFMGPGWTPAGLNEARECVNCGAVSTPLWRRDGTGHYLCNACGLYHKMNGMNRPLIKPSRRMATSRRAGLSCSNCGTFSTTLWRRNNEGEPVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPKNKISPGTLQAHQQAQQQQQQQQHHHHHQQHQSPSNKSLLPPSNHHSSNSMMHDVKLHSNGGSGGGSGAGLSHHSNSSSHHHHNHHHHLHNHNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY24</accession>
    <name>A0A1D2MY24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Heparan sulfate 2-O-sulfotransferase pipe</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfotransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000393">
        <property type="protein sequence ID" value="ODM97953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY24"/>
    <dbReference type="STRING" id="48709.A0A1D2MY24"/>
    <dbReference type="OMA" id="PMPIYVN"/>
    <dbReference type="OrthoDB" id="10019582at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001863">
        <property type="entry name" value="Heparan sulfate 2-o-sulfotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007734">
        <property type="entry name" value="Heparan_SO4_2-O-STrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129">
        <property type="entry name" value="HEPARAN SULFATE 2-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129:SF20">
        <property type="entry name" value="HEPARAN SULFATE 2-O-SULFOTRANSFERASE PIPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="52"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="393" mass="45898" checksum="766AF06D5DAC9948" modified="2016-11-30" version="1">MLSRFFSSEWIALASVSLTVFLFIHTQILTARIEEIKQEALTAAAAFSAHENHLSSASQEKSRGDFSGNNVHSNAQEQYSSDQQGGSSSGLQHHHRQYLHPKKKYNATALNNTRNSEKETLFFNRVPKVGSQTLMDLMQRLSIANGFQFHRDKTQKVETIKMTYYEESRLTTMVDMFTPPSVYVKHTCFSNFTRHGYSMPIYMNIVRDPIERVISWFYYIRAPWYIIERKQVFPELPLPHPMWLKKDFESCVLNGDRECMFIPGEYHDGVGDHRRQTMFFCGHDEKCVEFNGEWAMQKAKRNVEKHYAVVGVLEEMDITLKVLENYIPRFFAGASHVYHDNLSSMVKINKNMYKPPVSEQVKNILRQNFTNEIEFYEFCKQRLHMQHAAVTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYV7</accession>
    <name>A0A1D2MYV7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA pseudouridine 55 synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08440</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase Pus10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000371">
        <property type="protein sequence ID" value="ODM98233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYV7"/>
    <dbReference type="STRING" id="48709.A0A1D2MYV7"/>
    <dbReference type="OMA" id="LVISCQR"/>
    <dbReference type="OrthoDB" id="271937at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2510:FF:000001">
        <property type="entry name" value="tRNA pseudouridine synthase Pus10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3190:FF:000001">
        <property type="entry name" value="tRNA pseudouridine synthase Pus10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039894">
        <property type="entry name" value="Pus10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048741">
        <property type="entry name" value="Pus10-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048742">
        <property type="entry name" value="Pus10_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01213">
        <property type="entry name" value="pseudo_Pus10arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21238">
        <property type="entry name" value="Pus10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21237">
        <property type="entry name" value="Pus10_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pus10 N-terminal eukaryotes" evidence="9">
        <location>
            <begin position="112"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Pus10-like C-terminal" evidence="10">
        <location>
            <begin position="298"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00075270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00079393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00083669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="540" mass="61259" checksum="C3AC1FF148F37B06" modified="2016-11-30" version="1">MVGNCECAIIRAKMESLITEKGMRTEIIEDLAKFGCCNLCILRYLGNTEPYNYRKDEKLIEKLLFGELKKKNDNSCSKTGGRKMETDEGVEKENNLEDQDQPSRKVLKKSPCSVCLGLLDLKYGASDAVLDKIAAAVKEANIQAKSYTINLSLPIAVQFRAYFLWYHLVEKFSKIYNLYSMMKPESVCLKNAWKWICTHRLKDKVDPDSDWVTDGCLMVNISLKYEDDESECQTLGNQVRNSSDRRSKSNGLSRGGVELLFKDMTTFEFKRKFGDAPPIPSNFLVIDEICCTHIPVLVAGRYCKYSRNVSQTPWIVDGKRFHDASVEELIAHVVTPMMNADQVKFSASGREDVDVRMLGRGRPFVMEVISPKRTLFTTENMKELRNKINSSTKLISVRDIQIAERKAAAKLKDGEEFKTKTYCALCRVPEGIVVAEMLEKLNAMKLPIVLQQQTPIRVLHRRSLATRERSILSIKATPAKSPNLFKLRVQTQAGTYVKEFVHGDFGRTRPSVAEILECDADIVSLDVESVDFHWPPSIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZG7</accession>
    <name>A0A1D2MZG7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Failed axon connections</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_08244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000354">
        <property type="protein sequence ID" value="ODM98436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZG7"/>
    <dbReference type="OMA" id="CFPDWED"/>
    <dbReference type="OrthoDB" id="5809458at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03193">
        <property type="entry name" value="GST_C_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03080">
        <property type="entry name" value="GST_N_Metaxin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="4">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="3">
        <location>
            <begin position="276"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM98436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="47791" checksum="441B7EDBDE1CBCD4" modified="2016-11-30" version="1">MTCCEKAIKPAAKPHHRHHPQLLWKIERDKKRRSSKCQPKLKARELRSRRRSRRKRRQKRLMMNLQLKKLKKPREVRRRREEAAAAEKKEAAPPPPRVHKQDFQKDVVYLYQFCRTPVLPSLSPYCLKVETWMRLTGVNYENVDHKLKFRSSKGQLPFVELNGEEIGDSAVIISKLSQYFGIDPDAQLTKEEKNVSHALISMIENHLCWVYVYWRSKYPDVMIKGCKLSLQHALNSRIPNAILNVVFKLTYSRKGAKKVKAHGLGVHSAEEVLEFGKQDLRVLEETLGDKQFFFGDKPSNLDIVAFAHLSQIANVDKCVEYDLRDWMEENCPHLMGLLGRLRERCYPDWEAITSTLKMNTHLPEPEPEKEEEKESKEKEATKEKEPEKEKEEIKEEKKEETKEDENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0W7</accession>
    <name>A0A1D2N0W7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 13 member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_07775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000312">
        <property type="protein sequence ID" value="ODM98912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0W7"/>
    <dbReference type="STRING" id="48709.A0A1D2N0W7"/>
    <dbReference type="OMA" id="QINLCAG"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015137">
        <property type="term" value="F:citrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015141">
        <property type="term" value="F:succinate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF82">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="552"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="604"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="635"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="669" mass="72232" checksum="BEF990344362CF2F" modified="2016-11-30" version="1">MNWRGIAKNWRFFITFIVPLILLPIFFLDEDGSKKFRCAYVILITALFWMSEAIPLAVTSFLPVVLFPLLGIQDTGRVSRNYMKETNMMFVGGLIIALAVEYSNLHKRIALRVMTIFGASPVRLMLGVMMTTMGLSMWISNTATTAMMVPIVLAVLDELNKGGNNPANNKKQLEANIVNFAHSSQSTTGGKSSGAVAILHAPDPNPQLTVNSVNRSKDFDTITGSTTTIAIDDSSSDGDNDSAIVSSGLGNALREKVNESEVAGMKRALLTAAVVAANIGGTATPYASSSSGLLYRLLAAQRPITVAGSVIGLQCQNGILFAIAYASNIGGTGSILGSGPNLILKDKAHCNNGTLSELTFATWMAFNVPPMIVNVLIAWVYLVLVFFGVSGRGKDKTTARMMSKDNQRDVERMLKEKYKGLGPISFHEAAVAVLFLFAVSLWFFKEPKFMPGWSDLITTSHDFNIGDSTAAMLIVMLLFILPKNPSAMFRKENAGVKVEALLDWKFVQSNLPWGVVLLMGGGFALSDASNESGLSQWIGDSLIGLKDLPRPLILFIVMIMTAGITEVASNTACANVLIPILITLSKNLNLHPLYLTLPATVTCSYAFMLPVATPPNAIVFSVGSMKILDMVKTGFFLNVSCVVVLLIFNITYGSLIFDYGSYQGLNSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N217</accession>
    <name>A0A1D2N217_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger and BTB domain-containing protein 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07372</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000288">
        <property type="protein sequence ID" value="ODM99309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N217"/>
    <dbReference type="STRING" id="48709.A0A1D2N217"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="275" mass="30824" checksum="FD53ABF768960E4C" modified="2016-11-30" version="1">MHIQRDHVKAKNFFCDQCGAGYALDCQLKNHIASVHTEATPVTCHVCGFVVSNKRFIKKHMKAASEALKMSTDEVEAYEHEEVTDKYNVQFVEKVSYSRACSVKRHYETVHEKKTVICQYCNKEIATSSLYQHQSQTKLCGAKRKAELEAKSNSTVVVVKQSTPSSTITAESEINAPFFDPFRDNHQQFENLNQSKELKFAVLVTTMVFCLVSQSSWAFPAEVSPNAKKDPVSTAPFYVESHLPNGQKQITYVDKDGVVLGDTRWGGCGYKGMCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2A9</accession>
    <name>A0A1D2N2A9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000284">
        <property type="protein sequence ID" value="ODM99399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2A9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="18137" checksum="3C47AB9C0F22453C" modified="2016-11-30" version="1" fragment="single">MDPQRNRNLTRGVDGLINGSGGRAAANVKFHESSVNVEAKLVQASSPVFVAGNSEMESGGTGSKLEELLLADKKTFNKSWRDNFGTTSTSSVTAGNDNKNKPSSEKTTPVENPRKRLLMNALKDSMEEKAGAESENKSGSKGRKMMRWKTERRSDEATNRGAAANSASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2J2</accession>
    <name>A0A1D2N2J2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LRAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000279">
        <property type="protein sequence ID" value="ODM99479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2J2"/>
    <dbReference type="OMA" id="WHADCRI"/>
    <dbReference type="OrthoDB" id="8249927at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20485" checksum="1EA6A17849CD0EA0" modified="2016-11-30" version="1">MKDKKTMANFDRVSDWFDADSFKIFTQTVRSGDILELRSTRCSHWGIAIRIKQAPISPKSKSKPPKPVPDEIMVYHLIHSSKNRGQVGQFTLEEFWHADCRIRINNTNNGASLYSTSRLKAKADILQNAFIAHASTQLKWQTCGDFIRWASVEQQDDIIRRSPVTSRNPTSTNIACSSAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N376</accession>
    <name>A0A1D2N376_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Adapter molecule Crk</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_06943</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000258">
        <property type="protein sequence ID" value="ODM99737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N376"/>
    <dbReference type="STRING" id="48709.A0A1D2N376"/>
    <dbReference type="OMA" id="SMTRQEA"/>
    <dbReference type="OrthoDB" id="9204160at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030971">
        <property type="term" value="F:receptor tyrosine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007167">
        <property type="term" value="P:enzyme-linked receptor protein signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09926">
        <property type="entry name" value="SH2_CRK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11759">
        <property type="entry name" value="SH3_CRK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11758">
        <property type="entry name" value="SH3_CRK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035458">
        <property type="entry name" value="CRK_SH3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035457">
        <property type="entry name" value="CRK_SH3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051184">
        <property type="entry name" value="Tyrosine-phos_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19969:SF5">
        <property type="entry name" value="CRK-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19969">
        <property type="entry name" value="SH2-SH3 ADAPTOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH2" evidence="8">
        <location>
            <begin position="15"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="110"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="206"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="288" mass="32638" checksum="7B240D691AB23A01" modified="2016-11-30" version="1">MAKTLTFDPFDRRSWYFGPISRQDATDLLMAERDGGVFLVRDSSSIPGDYVLCVKEDCKVCHYIINKVNEDNDGTKYRIGDRYFADLPSLLSFYKLHYLDTTPLVRPATRKLEKVIAKHDFDGADPEDLPFKKNEVLTILSKDEEQWWTARNSLGRIGAIPVPYIKPQYDEKSNDNVMPTPNKPPSETSSQTSENHTPKKTCLEPNKDTYARVKQARVPNAYDDTALKLQVGDIIRVTKINISGQWEGELVMEGGKGGRKGHFPFTHVELIDYDPLTASPNPTIQIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3M8</accession>
    <name>A0A1D2N3M8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="3">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_06825</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000251">
        <property type="protein sequence ID" value="ODM99863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N3M8"/>
    <dbReference type="OMA" id="CLAHSKN"/>
    <dbReference type="OrthoDB" id="275301at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06624">
        <property type="entry name" value="STKc_ASK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000054">
        <property type="entry name" value="Mitogen-activated protein kinase kinase kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000487">
        <property type="entry name" value="Serine/threonine protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046872">
        <property type="entry name" value="DRHyd-ASK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046873">
        <property type="entry name" value="HisK-N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043969">
        <property type="entry name" value="MAP3K_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025136">
        <property type="entry name" value="MAP3K_TRAF-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF394">
        <property type="entry name" value="APOPTOTIC SIGNAL-REGULATING KINASE 1, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19039">
        <property type="entry name" value="ASK_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20309">
        <property type="entry name" value="DRHyd-ASK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20302">
        <property type="entry name" value="HisK-N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13281">
        <property type="entry name" value="MAP3K_TRAF_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="615"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="912"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1097"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1210"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="1138"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="912"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="940"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="644"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM99863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1346" mass="152893" checksum="0E1F58A31888FEC7" modified="2016-11-30" version="1">MKKNRTSTTDSVGSKSDNSGNTAIVRESARPKMDVAFVIDLQNPVHLSQRKKAFEDVKNACAMLNANCIHIQFEKLDFGEVNILETMYNADVALIDLSVDVQKNTLFYHLGVRESFGMKQNILTFNDFDIEITMPLKLSCTAYPFVTYRVLECGTCVVTMPNIISPAEESVMESRTPLGQKIKRLLQDVEIQSKAHIKEKFLSDLRKARETLTDKELSKALHAMKKRLDDPNVISGETVYNMLLSFREIQDYDAMVNLVDTLEFLKSIHNYKNCVNTPAIMYLYAFALNRRNKEGDREKALLVMIKTLEKKENHVPDLVCLCGRIYKDKFVESGYTDRDSLHHAIHWYRKGFEVQPNEYAGINLATLLVVDGNEFSECEELQHIGMVLNNLIGKKGSLSSLQDYWDVATFFEISVLAKNYGKAIQAAECMFKLKPPNWYLKSTIGNITLIKQFRKQDAQEQPEETIFHFWIEYFVEATKSEIGDTIRIPILIFEPSRVFMPSYVICNLGAEQKSLQIANLCLQCLQSKCKQRHNWLFTADMIKSVSLYKRDDRCVFFYVHENSDDFHMYFPNSHYREHFYNLVLKLTADQNNRFTDLDAALSEEQIRYEYEFDEQTKKVVLGKGTYGTVYAARDLSTQVRIAVKEIPEKNLGEVQPLHEEIRLHSQLRHRNIVQYLGSVSEDSYFKILMEQVPGGSLSALLRSKWGPLKGSEPTIAYYTKQILEGLKYLHDQKIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGISPLTKTFAGTLQYMAPEVIDKGQRGYGAPADIWSLGCTIVEMATGKPPFIELGSPEAAMFKVGFYKMHPQIPSEMSERAKKFILKCFEPDPDKRATAAELLEDPFLTESGRKKNIRATATQEFARSISVPADRVIAAEKAKRQALSSDDSCGTNTAQSDYEDSLSRRGSSGNIPVSPESEISKSSPIVGDGADQDCFYLLKKESQRRTTLSKVLAQDEKRICEIWVKNYERDVEIALLKKDHIARLMHGLQDYIEKNDRIKLEGAINALKEEFNCDGVAVNQIQLALFLFRDAVNNVLRSHNIKPHWMFALDSLVSTAIQFAIHILSPDHSRDTREGAGSGSDGIGSTSGVSTVNSLKSHKALDYPSSKMHSEYQEQLESCRLENERLMQELLESRKAYQLLLRSSIDEQKLNLHLLNQTTQQMRMIGQFLTLTPPTIMRSSETGFSSHHTLNSEDDTSSQAGVAEMPDAASSVVTSGDNSNSSCCHHQLIAPSAPLPLNIRDPKLVEFLTELHLDRISIERFLQEEYTYDDVVLLMTREDLKSLKLKGGIELRVWKAIMKQRRILDPEWCKAEYSTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4T0</accession>
    <name>A0A1D2N4T0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serpin B8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06616</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4T0"/>
    <dbReference type="STRING" id="48709.A0A1D2N4T0"/>
    <dbReference type="OMA" id="CINGAYT"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19601">
        <property type="entry name" value="serpin42Da-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="6">
        <location>
            <begin position="45"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="418" mass="47026" checksum="03DC1F3CD29A355B" modified="2016-11-30" version="1">MQNGRHLWLNIFMLIVVCINGAYTRRDSRSLALQSIAESGNLFAESIFQEILGGQSLSERNVLISPLSISIGLSMLREGASGKTLEEITNGLRINKDLNDEDVRNGFTELISAFKDDRNNDEDVRLQLANRVYVGQVYPIKQSFLQTARSHFFADAEQVNFGDMEAAAFTVNRWVQQATRNRIKDVIVPSMLTNQTAMILVNAIHFKGQWKYPFDPDNTREERFKTLSGQELPVKMMQLDRPRKMKFAKLPELKSSAVALPYTSQRYSFVILLPDPEVNLIDVERGLKDGMLAAIPSRMRSTSVDVRMPKLLLESSIDLIASKSLENLGMESMSTEFAEFGRLSEEEGLRITNVIHKAFLEVNEAGSEAAAASAFIAQARSLDIEPENAVKFIVDRPFIAYIFDSITRSILFVARKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N532</accession>
    <name>A0A1D2N532_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06292</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000210">
        <property type="protein sequence ID" value="ODN00390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N532"/>
    <dbReference type="STRING" id="48709.A0A1D2N532"/>
    <dbReference type="OMA" id="TIKTCEY"/>
    <dbReference type="OrthoDB" id="6278121at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23599">
        <property type="entry name" value="TFP_LU_ECD_Cold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.60.10">
        <property type="entry name" value="CD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045860">
        <property type="entry name" value="Snake_toxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10036">
        <property type="entry name" value="CD59 GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10036:SF3">
        <property type="entry name" value="PROTEIN SLEEPLESS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57302">
        <property type="entry name" value="Snake toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905042" evidence="4">
        <location>
            <begin position="26"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="154" mass="17609" checksum="56485942DC40679A" modified="2016-11-30" version="1">MTYHSASSMLSVFLGLSFLIGLSTGLECYVCTNQEGNIEKCLSTIKTCEYGEDTCLTEVRWGSTPYWSQGAEKQYYVTKKCSNRTHCEDRRKQFVHHCHRIWYEDWKCAECCQGDRCNYYVVLGAPGLRFSWLVIAASVITTVCVYFSKDGILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5M6</accession>
    <name>A0A1D2N5M6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_06105</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5M6"/>
    <dbReference type="STRING" id="48709.A0A1D2N5M6"/>
    <dbReference type="OrthoDB" id="249932at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042078">
        <property type="term" value="P:germ-line stem cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22655">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE TDRD12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22655:SF2">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE TDRD12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0221">Differentiation</keyword>
    <keyword evidence="7 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="9" id="KW-0744">Spermatogenesis</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="95"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="14">
        <location>
            <begin position="839"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1076"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1095"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1122"/>
            <end position="1133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN00580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1264" mass="143386" checksum="A2CE8F91CCE95CD7" modified="2016-11-30" version="1">MDHVKLKRDLDKLKLESQQKLLFVSETGNLKSAYQSLEELHLHPDIIARLNQLQFGAKYIDDDYLLRIVWSNIVGGSDSVIVAQEISPRSKFRRTLSYLLPILRLLTMNTHESPVPSYSKTNASLGPQALLVCSSVTTALTFEKNLKRLLEGTSVPLKVRLVHTGMTDWKELNSVDILITNVLSICQLMRGREGHKNSTTVNLQRLKYLVMDEVDGYLKLESHILGCLIESATLKHVQKFHVQFVICGSTWTPELKAFHLSMIKKGRTPNLYIEPLAEILNFAEATWQVDYAPDDSKRFERLKETLTQRMASHARCIIACSTFSVAVSILGVCKECNVMSKIVSSELNELATENASEIPTETEVLIVTDDMVSLGLISDCTYMLSFDSSREIPTQSESVERMRLLHIWNALPTLVNTDNWMIQKPVAHFLMTGQEPNFLRFFRFSKNLVNNVYDPELETFGNKLLDEDMHKRPVCKGVELFGYCNAAPGATCSFRHDFMASDFENLANAPFYGEIEFALTECLSPSEYRGTLLTHYEYKQGQRLLLKSFKDETSTRTALLKEHYATYGNKKFPSSFNKENVYAFWSQSEETYKRVKIIGKLPRTVGVDNSDIVNLYCVDSGNTLTASVSDLLSIPKEIASWPPLALRVILTNICPPSREPEYTSEHINIVGTLAKHSTIRAKVELSFVLLSRGETVWVSPMITKTEDKSLGTTSIRPNLIRYLAASLNSGHQDYLIESVRALGTNYHGHKHLPIDMPKRKCTDEIFDLSRPDNTIQWAHLEQSTEDEVIPLRIKTTFGINPWTFYGANVKHRKLLYTLEDELHDWVEAQDRNEYVEFFEMLRPNSIVAAKDADGRWERAMILDMDRQGDQPQYELFSVDFGELYIDTEENIFPIATKFVTRLPFQVVALSLEHVRPRDKSELWSTEEKDAFLDLIIPNGDSVFLDVAVSCKVVGVESPPPCNYYMAVALLNSEELGSKLVRNGMAEMVHCIPRLADALQNKLNSTLDEASSVDVSDLIDNGEESDTDNQPTFEEFLQRFDVCANFSDNPKSSGEKNRVVEDIKAIVKSSLGIQSFKQPQNASEAHVQEADATPIDPSSSHTISDINGTVDEPDSIAIPTAGPSPSTSFEQPTESEDSLLSPTLYWSQSTSEVFLTVKLPEIQAYIVHILMDCRTIQFKTLNPPNYGFELKLFEICTNHNELLTNQQLKIRLKKKFPCNWTRLLFDSDTKLPWIQEDPDYLQNASKDTKIRFGLVRPVHTRMFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5Y2</accession>
    <name>A0A1D2N5Y2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_06001</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000192">
        <property type="protein sequence ID" value="ODN00683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5Y2"/>
    <dbReference type="STRING" id="48709.A0A1D2N5Y2"/>
    <dbReference type="OMA" id="NGWVHQI"/>
    <dbReference type="OrthoDB" id="899at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15557">
        <property type="entry name" value="PHD_CBP_p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15802">
        <property type="entry name" value="RING_CBP-p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031162">
        <property type="entry name" value="CBP_P300_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056484">
        <property type="entry name" value="PHD_P300"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010303">
        <property type="entry name" value="RING_CBP-p300"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038547">
        <property type="entry name" value="RING_CBP-p300_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23570">
        <property type="entry name" value="PHD_P300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06001">
        <property type="entry name" value="RING_CBP-p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51727">
        <property type="entry name" value="CBP_P300_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="9 14" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Bromo" evidence="17">
        <location>
            <begin position="76"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CBP/p300-type HAT" evidence="19">
        <location>
            <begin position="295"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="18">
        <location>
            <begin position="707"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TAZ-type" evidence="15">
        <location>
            <begin position="707"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="526"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="819"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN00683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="844" mass="98481" checksum="AB0953753165AAD9" modified="2016-11-30" version="1">MGLAVDECLDNSISEDVKKANEVLGQQDAEQPTTPVKSRLQIPIPFEFKRPRRQNTRVFETNKLKKYLGPVLSHLERHEHSGPFLQPVDAEALGLVNYNDIVKQKMDLSTIRLRLETGFYIEPWQFIDDVWLMLDNAKRFNRKGTNVYRGAELLGKLFDEEVDRVMQEKMKYCCGKRLFYTPPTLFCVGKRVCIIPRETTYYSHGEQYIYCKKCFAAIPGDKVPLHNERQEIIKYVLKEEFDFRRNDHLEPEPLVPCRECGRLMHQICCMYLDHFWPDGYICENCRRPAFTPPVLLTAETLVKTRLSEFIESRVSNFLITSGAVDIKVAIRVVSSRDRLAQLKPQMNARFPERNGFPYRAKAIFAFLQLEGHEIAFFGMHVQEYGSDCPSPNNRRVYIGYLDSVQYFRPRELRTAVYREVLLGYLEYVRLRGFLTVHIWACPPGNDDDYIFHCHPPQQKIPQPGRLQEWYKTILRKGQEDKIVMEFKNLYKYILDEGLNPVDDLPYFEGDFWPMILEDSLKDIDKEEEKKKEEANANVTVAQGGPDSRLKKKPKKTIKRLSHHLAKDLPTKMINVIKRHQESFLVVILNTTEAIVNLPMRETEDGDCLLYADLMDGRDGLLSVAMERHYEFSSYRRAMFSTMLLLFELSHSEDQNVFMCSSCNLHFTKGFRCMECESESASVDMCPTCHDTERHIHDMTQIETKRNQTSQTSLLQLRMALVIGVLHAYTCFDDSCTRSTCQQYKQLYSHASACPRNSKDKCEECRPMAQLLKAHARFCIKVHCPVPNCSEFKMGFRLERVNKKFKHNRCLQRRMRMMLQQKSEQEPDSGEQTTIVDDIQPMELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6R0</accession>
    <name>A0A1D2N6R0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000181">
        <property type="protein sequence ID" value="ODN00921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6R0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="339" mass="38083" checksum="E303A1EE086BAB19" modified="2016-11-30" version="1">MPRKRRVPENDVPTHPPPPTRMTRSRAATVAQPKNVQEEKEVIPKSTMKTTEEKKTERKPQSSRKKAPSNPAKPKRARKTASKPAKSKRARKTASSPLPVLYHSTDEECEEMPRLHEPQSPHESFEVSNLEPPTLVMQQSPAHADAPIAGPSRGNQSYVFLPKRTRGNITASFYKESVPDWAYTSTTLYNIQDAKDITKKTIDNMKYDFWSVLKAGSGGFVRPVLTVLEDPEGFKIYFEICALVYKRGGKLKQEPLASVTAYIRTEKLTLFTFEIINKELADYNDITVKLMKKGAEQIFGTTIVRCADKTGRGQMSANDIEYFAKRAGWNVDAPGNVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7J9</accession>
    <name>A0A1D2N7J9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Protein kinase C and casein kinase substrate in neurons protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_05446</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. May form heterooligomers with other PACSINs. Interacts (via SH3 domain) with DNM1, SYNJ1 and WASL. Interacts with TRPV4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000165">
        <property type="protein sequence ID" value="ODN01239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7J9"/>
    <dbReference type="STRING" id="48709.A0A1D2N7J9"/>
    <dbReference type="OMA" id="AMAHVFK"/>
    <dbReference type="OrthoDB" id="10255128at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030100">
        <property type="term" value="P:regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07655">
        <property type="entry name" value="F-BAR_PACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11843">
        <property type="entry name" value="SH3_PACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000014">
        <property type="entry name" value="Kinase C and casein kinase substrate in neurons protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000009">
        <property type="entry name" value="Protein kinase C and casein kinase substrate in neurons 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF11">
        <property type="entry name" value="SYNDAPIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 13 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="18" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-BAR" evidence="17">
        <location>
            <begin position="11"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="16">
        <location>
            <begin position="408"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="319"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00064966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN01239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="467" mass="53881" checksum="64629F60689EEE52" modified="2016-11-30" version="1">MSHHSEDGMLIASSDSFWEPGNYKRTTKRIEDGYRLCNDLMQLVQERAEIEKAYARNLKTWSKKWADAIEKGPEYGTTEAAWKGVLVESDRLYDVHTTIKDDLHNEVIGQIRGWQKDSYHKNVMNLKERKEMEDMFKKVQKPWAKLLAKVNKAKADYHNACKNEKSALNLERNATSDTSLSPDQVKKLQDRVAKSKEEVQKTREKYESALQEITAYNPKYIEDMRDVFDKCQEMEAKRLKFFKDAMFSIHKCINISEKPELPQIYEEFYHTISNADHMKDLKWWSNNHGVNMAMNWPTFEDYSEEFRDITKSRIKDSVPSGGITLLTQKPVSDDLPAGGPQEPQPVQMTKANSIKAKTNGSESKVTKTKEKEEIKPNGSGKGERGNPFEEEEWDEYSNNEGALVDRGEPGIPVRALYDYEGAEDDELSFKQGDVFEKLEDEDEQGWCKGRKDGRVGLYPANYVEVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7Y9</accession>
    <name>A0A1D2N7Y9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000154">
        <property type="protein sequence ID" value="ODN01393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7Y9"/>
    <dbReference type="STRING" id="48709.A0A1D2N7Y9"/>
    <dbReference type="OMA" id="MIPQTED"/>
    <dbReference type="OrthoDB" id="5832575at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039139">
        <property type="entry name" value="CCDC170-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18863:SF6">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18863">
        <property type="entry name" value="TSEC-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="19282" checksum="A8A4FE98DB41402A" modified="2016-11-30" version="1" fragment="single">IIALERARKIEDTEKKLNELELLRCKYNRKVGFLKDQLKSYRDTTTQERDLHDHAFQRLSEELNASKKNLLEASRRETQLLNLRNMIGKILGIDWCKTVVPDYELISKLEKIVQTNREFAQVSRKLTDNIKMIPQTEDPGARFTSPSPRGSEDSNGDDMHIRRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N894</accession>
    <name>A0A1D2N894_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05488</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000167">
        <property type="protein sequence ID" value="ODN01196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N894"/>
    <dbReference type="OMA" id="HFIICHE"/>
    <dbReference type="OrthoDB" id="8298631at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="6">
        <location>
            <begin position="303"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN01196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="360" mass="40808" checksum="9B25F46D7BB06D64" modified="2016-11-30" version="1">MSLRDELIHNEIQHLGQMLQTLSYELTILQDFIKDKFGSDFESFRENLTCAQQHSSTTPKETGTSSRSGNITARKSTSKPGGLKRSDGTRNTNDLAEKRHKDSHVAAQKHEESDSSSDEEKPITIRIESVVSGAGAEQYSNDEENSRTEDGADDDDNSEMEFPIDEKNVIDLMDEEQKVKGERIDFSTPPLRQRKPRSEIWTKFVVTKLPNGKFHVRCPICKAPVSSKSSRMEKHFKNCRQLVADGGATSNNSPGPSTVSSRMSLADEKRETFKAMRQVKKEKLKIVSWESRQRPGGPMGPGRRLDPVWAYFNVTDDPETGKKVAICKQCESRVSNRVHRIRRHFIICHELEKEEQEQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8S5</accession>
    <name>A0A1D2N8S5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-ketoglutarate-dependent dioxygenase alkB 7, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000144">
        <property type="protein sequence ID" value="ODN01663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8S5"/>
    <dbReference type="STRING" id="48709.A0A1D2N8S5"/>
    <dbReference type="OMA" id="VEPHMKR"/>
    <dbReference type="OrthoDB" id="548214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032870">
        <property type="entry name" value="ALKBH7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052:SF0">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052">
        <property type="entry name" value="SPERMATOGENESIS ASSOCIATED 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="34137" checksum="8EE243028D6625AC" modified="2016-11-30" version="1">MAASLRNLVFTVRPVTIKNWRRLPYIVPYIVFDCCEGQFWRGTNNVRKCFSTSSKVDESVSREQTEEQRQGMGEHFDMSQSFQKTQDWRNKLLESMLVYPNFVSVEEEGAILKEIEPYISRLHYETSHWDDAIHHYRETERAKWNHKNTEIINRIRSLCFPPGVPQLRFVHILDLAKTGVIKPHIDSVRFCGNTIAGLSLLSDSIMRLRHDVQKDFYCDVLLPRFSLYVMSRDFVRYEFTHEILGEKDSKFKDRVICRDRRISVICRNEPEPATSSSVTGPEFKPLSPPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N988</accession>
    <name>A0A1D2N988_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">DNA transposase THAP9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_04843</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000137">
        <property type="protein sequence ID" value="ODN01823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N988"/>
    <dbReference type="OrthoDB" id="5982876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026516">
        <property type="entry name" value="THAP1/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006612">
        <property type="entry name" value="THAP_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46600">
        <property type="entry name" value="THAP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46600:SF1">
        <property type="entry name" value="THAP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05485">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00980">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50950">
        <property type="entry name" value="ZF_THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="THAP-type" evidence="15">
        <location>
            <begin position="29"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="127"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="357"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN01823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="421" mass="48019" checksum="AD5EE4F35EA7D896" modified="2016-11-30" version="1">MYSAGGMTMSMIQARKDRRGKRAELPDDIAKKLKSCSVLSCEEWRDLSAYTTYHCFPTGEKNQERWEIWTQLLRKAREDETWIPFRGSLVCSHHFRPTDFISDPLSKRRKLMKNSIPSIFPTFTVDLEDPSYQVPEDQMGDDEVGEESYENNDDNSGTYYYEEENGSSMLTNSNSNLYEEEYDYKYASDANGSIQNGDSSYGSNVFEQYDDDDDDDDIQIIHDSESESNSNAPSSVPAGIHILSTSSLSSTTAAASQQQRMRTPPQAPSKVILVSNNATRVQNVVVHSASNAGRRKQQHQQRATVTAVKNIPFQPNRQQNSPPKLSRQEETAKAISSLPFSLNPDLEIEMIDPTEDLAASRLRISELEQQNKSLINMYESAMEGLKLKYENQILFLRKRMKEQERILEMNQIPLPKRTRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9C5</accession>
    <name>A0A1D2N9C5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Reticulocyte-binding protein 2 a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000136">
        <property type="protein sequence ID" value="ODN01860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N9C5"/>
    <dbReference type="OMA" id="NIASASC"/>
    <dbReference type="OrthoDB" id="2386367at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905250" evidence="2">
        <location>
            <begin position="29"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="domain" description="MACPF" evidence="3">
        <location>
            <begin position="563"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="927"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1349" mass="153125" checksum="AC74862B1F16F599" modified="2016-11-30" version="1">MAFFAKTLPFQNGVVLFLLLALFKVSLGQQNPYLEKTCAVLYSGDRFSSDELTLMDGDQSVNLEEDNRASSGWNTTGSINIANGCKMDICNETYFDGNCHILEQGAYYLSNLTKEFGDNIASASCRCQKECKCSDIFMKRSTCARAYLKGGCRTCHSLYTDLSDSKTYFPDDFVGKVEALRLRRGCTLTLYPEEDFDGEGEIVDSEIVEDYKGEFRSYECVCNDAEYRPRVRPPRPASLPALVDIPDNVDTIIKMLNNKTYAEHPGLLAALKSMKSGRSSKNVYILLLGSTGAGKSSAVNNLLLWIPNISKVSEKKKSSKRTDIHEFRIPVPVDELGVANSELRVIDTPGLVNRAGICLKGLEGLDAFRERITDENYSNCIFVLSHFCSETKATKRKPDVRLSQFKKVIEDYSLFPRPIIITVAENKAKDQELPMVNGFFKLPNNEFYPRNLYEKLELVTKNGGDMMGLGVFRTAFRDSEGFNVSSITFKLVEKGGSKVEYYLRILSNAFFGVEKTQISQLLQQVWDEKVDATLRKQFPDSLHYLQKSLNIRNVNTMEDIPKTTTAILELLTAIKHDEATRALLDKALNIKPPPFQQNPIAGYSYNVFKDTYLPTSPFQLGDLQQTDIGFMVPKILTCKLEPSSTQNFFVFDNQEQYLQHRLHSLGIEGNIPRESFKGTIKPGHNIRSISFKNDSCTLSATREFRHFEFILNERLDYTPEFVNAVKALPVFNEEDHDAVDKWNAFFNEYGTHTVSSVHGGGSIEIELQSDKPFNDDMGQALFDLIKFAEDMSFLVADESENGTSNANKTVFAPGIQHTLSFHGGDSQYHTSDFTKMPIEDASKLLTRWKKSLKFNPAVLTTEMRLKPISQVVKKIGQNYSSEIERATSLLFNSSLKYVPVKKPSRTEAAPGLARDDTPMMTQLLMEQQKSNQRMQELMMDLKKIEQQNEERRQVLEQQRLAWQQEQARLQQEFRMQQMTMQHAAEEKRQEMAAQLEAVRQQQALAREKQQREYMDQVTKAQEAAAARSLALMREIANRPQPSGGGGSCLKKGTKILLSDMTEKSVEELQVGDIVLDKDMNPTRVLGVAYEFLLDQKFYGFDNESFFFTDSHMFVGPSSAGDISLYAKSTNRLFYNNPLLKYLNVNDMDKTERLPLFHRVGERQVSVENVFVTADPVEYPIDTPIYFIQVDSPTGTYFANGYVCRHEIPPVEYWPNTMSILFKLMGTDSFEKLSQLSYTIETVNFLLDVSNKVAATVKQFIESSEWRNAKTERNYKVMTLEDINMEECISKIFSNPTLSTAGVSLYARVGDIIAPYLDSIETEKQVDPSELGRLQHELYQILSQELEKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9G4</accession>
    <name>A0A1D2N9G4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_04797</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000135">
        <property type="protein sequence ID" value="ODN01900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9G4"/>
    <dbReference type="STRING" id="48709.A0A1D2N9G4"/>
    <dbReference type="OMA" id="PYWERTH"/>
    <dbReference type="OrthoDB" id="446635at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16475">
        <property type="entry name" value="RING-H2_RNF121-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040176">
        <property type="entry name" value="RNF121/RNF175"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407:SF0">
        <property type="entry name" value="FI05221P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407">
        <property type="entry name" value="RNF121 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="222"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="38216" checksum="856BC3F84737473B" modified="2016-11-30" version="1">MDEPSDLLDQLKESEQERFRRELTPQEELRKQHIQFHEKHKGHEQMHAEMFIILIFTLLIAQIVLVEWKKRHYRSYMFMTLLGMWTVPMCFSCYNLWYRFILSWLLFTSLSGVVVRKALEKPLNCSTPRLVYKWFYIIHKVSYGMGIAGYCLMMATIMGLNFIFSANPHNWMDCALLLLFYGLYYGVLGRDLAEICSDKMAVKIGYYSKDGFPTKTPDDNICAICGNPLLVSTEEEGVLEDTFRLSCNHVFHEFCIRGWCIVGKKQTCPFCNEKVDLKRIVRNFWEKPHLLYGQLLDWVRWLVCWQPLIYFLVQGINWILGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBI3</accession>
    <name>A0A1D2NBI3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter G family member 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBI3"/>
    <dbReference type="STRING" id="48709.A0A1D2NBI3"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038:SF3">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 20 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26948" checksum="F2928DCB923F74E9" modified="2016-11-30" version="1" fragment="single">YSLIGSSGAGKTALLSCIVGLRQWDSGSITVLGRKQRSSENDFLEIGKRVGYMPQEYALYEHLTIKEIFRYYGKLYGMTNSETKERWKFLSKLLELTSKRYTKIQNLSGGERRRTSLSLALVHRPDLLILDEPTVGLDCLVRQRFSNTIGMMRNGQLIFQDSPKSLLSIYNSTGLQDAILKMCKNSQKTLSNKIPVDFVSKVKALNRLHEIKFQYNGKTSPRSSIDLPDGKLDKTVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND18</accession>
    <name>A0A1D2ND18_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proto-oncogene tyrosine-protein kinase receptor Ret</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03522</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000085">
        <property type="protein sequence ID" value="ODN03157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND18"/>
    <dbReference type="STRING" id="48709.A0A1D2ND18"/>
    <dbReference type="OrthoDB" id="3256376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055162">
        <property type="entry name" value="RET_CRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF617">
        <property type="entry name" value="RET ONCOGENE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22540">
        <property type="entry name" value="RET_CRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="625"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="658"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN03157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="889" mass="98402" checksum="A728DA8CF52D1128" modified="2016-11-30" version="1">MDIANITHENFTGVLSAAKAGSQEPLPNMLITKAGFDREEVELYNFSVSCIVTSSETPNKHEVIATAANLRILDENDNTLISSSDGTSDVTVYISLSDIKYHLEPGKRLVPRDHSELLARDNDTVDVNNFKIYNLNDTKRLLELDFTQHQIATEGSMNYTALIPKLKLSEHVQGLSPWEGDYCVAAVINDSTVAIPEKRDQDLKYTICVSWGQKPSSPRPESQSTDYLLSRLSNHVDQARMPRSTQRLAPVLSPFPDLVTDVSDTIAGLEFSIVYTMAYAFEEDLESNSAEPGTTMIASADYNEIFDVTPHMGIIYLMHPELIQNSSFQSFQLQLLCNSSLIPSFTTNITITLESPVTSETLCDDELCSVHADSKSCEQSCGYGSPGKCFWRQKPGFNNSLSNDDVTDQPVDIAQYPTCSPHLGTCPDGKCDEMEQLFPHLCPQDCATKLLGFGRLLEHSNGRFYGINGEFCKGVGTCQDPTICSCAHLPNPVLESPLSSLPKPTNIVSSRTAVGMDCGFNCVMIYLAVSLIGVFIMLVTIYVLRQRKERKRKARSLNQSVMMTAAGIEIGGGYGDNTGNGTLISNAEYGPGGMNHAVLMVSDDQFEANQIVQVDIKWEIHRDDLTLEHVLGEGQFGRVLKGKLRGHSGGGHTPVAVKMLKVDAAEGSKSLWQEFMAEFSLLKQVDHPNVIKLLGACTTTGGPPYIVMEYAEYGALRSFLRKCRRVEKINGSHSALHWDNPDSSVSPASDPLNVEYVVTPREVLGFSWQIAKGMAYLSDMKMVHRDLAARNILLTRTKACKISDFGLTRDIYVDDAYQKKSKDRVPVKWLAPECLADELYTTKSDVWAFGVLVWELTTLEHLHILESQLNNCTLFLIRDIECTNLKTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND69</accession>
    <name>A0A1D2ND69_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND69"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="10945" checksum="5CFB1C192047B9E3" modified="2016-11-30" version="1">MGCCGSKNMDAGAPPEVQPTASQGQPMEAAPSNADQGGMEAAEGGVPMYIQLIAPINSMYLSPSDVFIHPAGWKPCASYQVDFYAVPNQPPRRSNIRSFIVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDM3</accession>
    <name>A0A1D2NDM3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KCMF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000077">
        <property type="protein sequence ID" value="ODN03353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDM3"/>
    <dbReference type="STRING" id="48709.A0A1D2NDM3"/>
    <dbReference type="OMA" id="GRRPNMH"/>
    <dbReference type="OrthoDB" id="7873042at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010646">
        <property type="term" value="P:regulation of cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023051">
        <property type="term" value="P:regulation of signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099536">
        <property type="term" value="P:synaptic signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02338">
        <property type="entry name" value="ZZ_PCMF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008598">
        <property type="entry name" value="Di19_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050774">
        <property type="entry name" value="KCMF1/Dystrophin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12268">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE KCMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12268:SF13">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE KCMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05605">
        <property type="entry name" value="zf-Di19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="10">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="137"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="218"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="320" mass="35133" checksum="A444477EBE3008BC" modified="2016-11-30" version="1">MSRHEGVSCDACLKSNFKGRRYKCLRCYDYDLCANCYEGGAATSRHTSDHPVQCILSRGDYDLYYSGESSTELAHSLTCPICGRLGFTESELQSHVTSEHQNSNTEVVCPICASMPGGEPNLVTDDFTAHLTLEHRQQPRDNYVEEAPSARHSLRRVQQPSRTLGVGRGRRPNMHFSSGGLSPSGAREAVDPIAELLSQLSGVRRAAAVPYDRLLHRHTTSSQQSSSAQGSSSSAAAGARRSVFPQPSGGQTVILADQTATMQPPNPMDSGTQKHDKHQFLLDKCLDSQRRRDLNPDQSLFLQDLLLATMTLEDKDNPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDN6</accession>
    <name>A0A1D2NDN6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000076">
        <property type="protein sequence ID" value="ODN03374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDN6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="432" mass="47048" checksum="295D7BF9674A642D" modified="2016-11-30" version="1">MAQELTEETDRILLRSEISISLDQGLDQIDLLKPVNKSQQANLSGSATNIDHTANNSAALGDVVRGRAQERFLTGWKKGGITQPEDIDPSWLVNSMDADSDCGRRLSTCLNSRPYHSDLESSVVSNSNEPNRSRRRSRRVGQVSLPTQFPADSPHSYNIPPPGPSTSKVANGSISIPDGSIQAKQLRLLDRKISMYFGERSSSGGSRPPPTVRKARSYEKLQSNSSKALPHNLSLFSPPQPTELHTREKENASKYEDPTPTVTTISDIETDNCDFHVNPPIELTTAVGLGKDLDKSQEDTTTSSENDITTAVTPEQPSGSTVVFNGPSIEEGSPYPTTLSISSVELVVKQTVPSSFAPKDNNQYDIVEAESQSNVYVGGGGGDDDDPIASLLKETEPDKGLDEESDLWNRMEALSSYQSFNLIRKSTIDPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE23</accession>
    <name>A0A1D2NE23_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine/threonine-protein kinase ATR</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_03204</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000072">
        <property type="protein sequence ID" value="ODN03482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NE23"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08064">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00802">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="15">
        <location>
            <begin position="1781"/>
            <end position="2390"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="14">
        <location>
            <begin position="2496"/>
            <end position="2805"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="16">
        <location>
            <begin position="2814"/>
            <end position="2846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2297"/>
            <end position="2316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="2297"/>
            <end position="2312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN03482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2846" mass="324964" checksum="F2E18612477C4332" modified="2016-11-30" version="1">MSKRKRSSESNDLNTSNRASKAASHKNPSVHNNHGRNRRGGVESDDLHEVVDLEADDDEPEAAANIGVGVSASKKKRMEKAKESRTMKKDIKLDNRQPSTSLTPPLSAEPVSEREPEVFCSAASNIRSTKNGDGNSNSQYLTPSDSEPLEFKRPGVPLFKKPYPPVLPGPSSSSHQTVVVGEKMGPTEKQLQATQKSREMRKAIIDVLQATLEDASKCSIASVPDLLENFLPCIKRMSFIFASRRYPGQRDVDDLSGEDEISDLARWWLFGMTALLFSTPADGVKKMKEAVKYMIRTVCQFLCNGHPKVVDSIIPLLINVIRDLTVRGDNDQMRVLKLDLPSLECSSSGPNSQKSIYNIQLTVDNEWAIPHFMQSISAVLPRIFFYHFHLRHVLVELLNRFLSRQSCESVETAVTSYSSPAMPAIAYLTEDCIVSLIQRLVESPSLPGINLHQLSLLVGQHGTTFDAISEDIGMNLLPLVLPEYLHSKNFSLLYHNENTVIIADAFRSLMDTVPIHHSQIISCESIKFSKLVSLAGLNVILNPLLEKILLAELENESTGSGPNFQANWSLQHPLRIVKVWEVSQLWSKIMHQWESSLYTVSSHGTPNHEGAVNFMKRSSVFIKLAKNLWNGVYPLLTTKRVRFIFFELKHLQRWFSSRDGYEIHLAILETMESFHACNWLGIKLSPKVLTNLISIPGWPWIANFDAFLPQKYKPLHSFTRLDVSNIIGSKVLVAKSIRVLGSEVFRPWTHFVTEVYSYIINAESTLANSVLVIELLDMIADVRWPFKQMPIKIIFTFVAQIVNREEWKVNSGLRTSLANAIVALPCLCCSVNLGGMNPGNEFSIIKSGCHICSRKQENLANMAQPSIPDYLTQRIASLASPLLRSKFLLVKFQLSDLIVRFASHSEKSSTQVTLPFMHVVVTGKVDLSENVFQKIGVLLTQVGNLNNPCEYRLGLAQQIFTSLRRLMVNSTSNRKISTNKLSKVLKGFFQLATYPLSLSVFVELVKCIVFFLSQTDKSEVTILCQKIVAKYASVYQCQPFDLIVRIRQDLSREIIKVATKAFFVPPESRDYYVNVQQCADFLARLFLLGEFRYGKMFISYYYPAMLEKMVPKLPTRYGYRFLLSAMASHSKQIEQAVLQDWVMLYYPTLLLDHNSETVSTCLQFLKNHYGFVAIFAAKQQEQRILNEALCRLSDQREKLLRCLPHLCKFDEDSSQMMYNAGTSKAMSILEIQELLSKRLLGFFLHLDTKLQSRIETVESKKKILRSFTSLLDLMKEKKITPLRSKVYKTLSSMTKEGPEYFKELFDAWKVFADNLDAEHFGPMASQILAAVLPLRNSPLRNDVDCLISHFVVFKKKLTEPHYHELYFLIEHLKKGDNEDTRTKSEKAKVINAVGGKINEMKNNWLEYFMMIVKESSHENVHIRYQAFSKLLDVFRHESSNFENKVLTRGQMHVSQVISALLAGLRGDSSNEKLKTLIIECLGNVGALDPVRFRSEDDDLRTKSRCTTYSGQMTTFAVLYLQELIREFQEAKDTTSFDYCACLIQQVLQEFKVFPTNEDPIWSCISPASQHHIMHLLTTKYQMDTTSPPPTVYSPIYLSEHGLTFDSWLLNWLTVLISCITTEELRAHSLFNKNKYLLRRNPRIAAFIIPYVTMYAIFCGNAEQREEIVREIITVLERWTVLDAMKVKAHSTVPIKDSQTEFGVKEELSVENESVFHFRCTQVIFSVLDHLLRSFKLAKRKWGLKLASERSRGPSSKTIHPPMSEVNMKNIEAVLEKIPANLISQVAFDCGSYTIALYYLEQELRTNPSNEKLQRNLGYLQRIYVSLNDMDSVIGIAAVRDSDPSLCEIVLENIAKWKMEDCVRNLEKMTANDPSDLIAHNALVQAYLNLDEPRKADTLIRGTIQKRSEWELAFQDVQLESLVKLKNWPELNTLVGRVEMTPSSCILDDTSFTWNTDLVRTISKIQQMLFNDATEIVERIKSKMIAPLVAASEEMYPYKRAYHNVVQLHILTEMEDAIKLLQTHLNYIASGKGQSTQGKLFHDVKRMMTRWDARFRNVSKSMTVIDQILNVRKCLFEIMKTTFHTNGSVCEVLNSAIRECWLDVARDASKCGNFIRADNCLMEAKKFMSPKVLIEEAKILSRKGEKEHAISVLQKGIALYFPQKDTWKEQSSSDHASSYETLDARILCSKALLLLAKLCEEEKLLNMEDYIAKYKEASDVYRDSEKNYFTLGSYHDRLWSSTERRENHFHIQATVVRYYSQSLLYGCKYVYQSLPRLLSIWFDFAAALQSGEYSKVNSSSSKSASSSSSNQSNDNIPIMKPEDVLEIMAAAIKRMVAGIPAYILITAFSQLISRLCHSHRKTWTDLREIIVSIICAHPHQTLWMIMAVTKSLNSQRKKRCLEIYTSVEKTKSELKPLIRSYTELTAKFLAVSDYPIERNKGSLTSVCPSLPNMIRNSAFGKVSIPFQIFLNPSLPRVGNNHKEHEPFPESLVYIEDIEDNIDVMPSLIRPKKLTLRASNGKSCGLMCKPKDDLRKDSKVMEVNNVVNWYLNQITESSQRRLHVRTFSVVPLNEECGLLEWVPNLQGLRPILLSLYKEKNITPNNRDLRCTIELHDTLEVKMEKFVEKMVKPHPPVFHEWFFNNFNDHQSWYEARMAYIRTTAVMSVVGYIMGLGDRHGENILVDSATGETVHVDFNCLFNKGETFEWVERVPFRLTQNMIDAMGPLGYEGVFRRSCEIVMNMFREHKSVFLSVLRPFVFDPLVEWNRNRDDRRGCSSAAGQHGGELTNEKAVETMKYIRNRLNGTARNLMRDINTELSVEAQVKYLIDEATSIENLCQMYIGWAAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEG9</accession>
    <name>A0A1D2NEG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Germinal-center associated nuclear protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NEG9"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="14"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="432"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="484"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="344"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="484"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="498"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1563" mass="173823" checksum="F54D724006AD1CE9" modified="2016-11-30" version="1">MESSTGDDASKKKSIVVVEMLEEFINRDILKKHFEKYGTVERLACSVSKRYAVIHFSTAEEADYAMKNGKIIKENAPPLKIFKSAKAAPTASQAQAQAQKSTSSGPPSTTRVVLRRKLSRTPVSTSPTSELPLSIPTTNVVNKSPEPPSTSQLGPLRSSIKVSRPSPFLRKRPSLGDRTGKSGPPMVSRNPFALPPRNMLTLDRRKEKISPGGPSISTSDLGSKSSPSIRKILKAATDKTISVNITLKESEKEQKPVVFQGAAFISPEGGASTTRDENDVTASTQSHSQDVPELPSSLQLDADENTEDVTETPGIESGGVDTNENDGYEFEEGDAGTQDTAEATTEEEEEEEEEGEILDDEDNDNEEDPDDEQDEEDDDDVYESPMKRFESEAKAAKSAAGGGFSFKLSKDNNSSSGSLFKLPFTSPFSLGDAPKPFSSASFGGAPKPFSSSTSFGDVPKPFTSTSLGDVPKPFTSTSFGIKVSASSGAKPSLSASKAADKADAPKEKQKEKPFVTPASLKKNDASEMEKAKPFPFGIFSSAGGSAASSKPVAPIVDVKSSIFSAKTTSSTSLPKRVGISAPPPPASIVATTSQVVVVPSTLQTQRDVPNPLLLSFNPDTPEAQELFSKRAVTVEERYRILEARDKIIRSRVPKTKVNVEEATRLIGTCPDMCPEKERYMRQFQRQLVGYETLPGPDVAVDHQRAIKVYSRSSADQEEPLPHELRPGPTLDYTMNYLLQTIVPLGDNPDDNLSDWYHFLWDRTRSIRKDITQQQIIDLTAVSLYEKCTRFHIHCGSRLCELDVHSFDPKLNDENLMKCLQSLEHLYEDLRRRQVTCPNEPEFRAYQIMMNLNEGDALYNAQQLPSWILNSTDVQIALKLHHNIYTKNFVAFFKSVEGLPYMTACILHRYFFQVRSLALRCLMKAYCTLPKFETSMPMSTLQRMLGYGLEEAQYFNYLCEAHGIHCDIEDNKVILKRKMFYLPEFPSIYREKHLIDSKLRTSVAEAVNGGPLPNIDFGSRIPQSSFNENGQLIPGDIVGSSSGNRAVISATISQNPESTTVKQLPKAIQPIIKSSFPFARVFQQRKETPPAPVLVVAKPEKEIDAACQAVTARLIDESIKQDIVELSEARLAEAKKNQEIAARKKLREEVATRVAQEFIEKAINQHVENVVRSQTISRIRQFVAIEEASKMALESLVDETVLINTSIAARTELILAKELHHRQLRTLKEIFARVRARFAFGKWSAYTRRKKLERELQQEKRREELWNFPAVNSYSLTTKDVYNAFCGRSSVQPSINKVDSLVTVDDLIKTTLENSPDSLTAPRAKRRSGGDSEIFPIPAKLPKLSPDISPMTVNRLRELWEFPAIDSYSRTNRQVLEAFCGSSVTKNSSVFTSSFTPIRKMPNFGPINFNKNTPFFRPIGSFSSDGRYSKEIQTKSAEGTTDMLKSVQNFLSQVREETQKLDSLETYQKSVDDMRKTCPLIDSQIESASAAHSARNAGDFSSSYSEFNNPEWMEVDNTAINMAALNFDNDDLLNCIQRFVLKIREEKAKSWNVDTFLNDIEVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEM4</accession>
    <name>A0A1D2NEM4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 18">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 18">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_02990</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 21">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 18"/>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEM4"/>
    <dbReference type="STRING" id="48709.A0A1D2NEM4"/>
    <dbReference type="OMA" id="HPMSLDF"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 18 24" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 18 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 18" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="23">
        <location>
            <begin position="176"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="34"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="514"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="515"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="564"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="22">
        <location>
            <begin position="593"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="19">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="19">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODN03677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="616" mass="69880" checksum="87DEB7F0E5EE928E" modified="2016-11-30" version="1">MASASTPPGRYEYAGYSEQMLEGAYIPWKPTEHPVCDGQFDDDEDDEGVETTITVGKEVAGSASQSGSVPSGGGVTNAYTRVEGAEDINSEEEDDEDTDYSEGYDEDDYQFWDERNGPNCQSNHKNLQTSDELFRKFSSKISVEKYEGVENLPSGAGNKILSTNKRALGQRVKVKDKQDRATVEQVLDPRTRMILYKLLSSGKIVSIDGCISTGKEANVYHATGPDNSALAIKIFKTSILTFKARDKYVSGEFRFRQGYCKKNPRKMVRLWAEKEFRNLQRIHTTGMIKSHVLVMDFIGEDGWPCPLLKDVKFNEIEFNDNEQNSDQVAAETSENDPVLNLVANLYKQCLVILYRLFNHCKLVHADFSEFNLILKDNKELYVIDVSQSVEHDHPRSLDFLRHDIKNVQEFFGKHILVGDYKDIFEFITSPTVDDSNCDAVLDGILKNAKKLESFNVSDEVFRQTHIPRKMQEVVDYERDYQKMKMGETELVYTKIMGMKSDMSGPEVVNRICSRPQESSSKVDDSPQTPASAENKENADRDGDDESESDTETVSTSESEDEEGGKEVASRPKNETAEEKKLRKKQVKEEKAEKRKSKVKKHVKKRKEKLAHANSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFX2</accession>
    <name>A0A1D2NFX2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NK1 transcription factor-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02552</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NK-1 homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000054">
        <property type="protein sequence ID" value="ODN04144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFX2"/>
    <dbReference type="STRING" id="48709.A0A1D2NFX2"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000315">
        <property type="entry name" value="NK1 homeobox 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF37">
        <property type="entry name" value="HOMEOBOX PROTEIN SLOU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="79"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="81"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="228" mass="24578" checksum="00A0D031FDD7AE81" modified="2016-11-30" version="1">MHADPDSTTTTPPNSDLLTSPCETSYGDDENSCDLLLEDENYRSESESVTGDDPLSLDKGSEKGKKKSSKSSNSDTKSGKPRRARTAFTYEQLVALENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDVNSPPVPTPNSGGLGSFGSANSPYSAATHHLLYPHMTAYLAGGSVSSGSALASAGSLLSYHNPNGGPPSNSFSSSYFSHLSHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGA7</accession>
    <name>A0A1D2NGA7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase-coupling factor 6, mitochondrial</fullName>
            <shortName evidence="9">ATPase subunit F6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02418</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ATPase subunit F6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000049">
        <property type="protein sequence ID" value="ODN04262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGA7"/>
    <dbReference type="STRING" id="48709.A0A1D2NGA7"/>
    <dbReference type="OMA" id="SICAYST"/>
    <dbReference type="OrthoDB" id="8902296at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.110:FF:000001">
        <property type="entry name" value="ATP synthase-coupling factor 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.110">
        <property type="entry name" value="Mitochondrial ATP synthase-coupling factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008387">
        <property type="entry name" value="ATP_synth_f6_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036204">
        <property type="entry name" value="ATP_synth_f6_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12441">
        <property type="entry name" value="ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12441:SF10">
        <property type="entry name" value="ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05511">
        <property type="entry name" value="ATP-synt_F6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002455">
        <property type="entry name" value="ATP_synthase_coupling_factor_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111357">
        <property type="entry name" value="Mitochondrial ATP synthase coupling factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0138">CF(0)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR002455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12037" checksum="1B0B2FEF87B18D45" modified="2016-11-30" version="1">MAVIPKLQRSAFTILKRNIGFSAILAQKGQAVDPIQKLFVQKIREYDQKAKASPGKLVDSTPAIEKELKTELDRVAKMFGGGEGVDMTKFPTPNFQEPALDPINHQATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGK2</accession>
    <name>A0A1D2NGK2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Neuferricin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02294</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000045">
        <property type="protein sequence ID" value="ODN04393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGK2"/>
    <dbReference type="STRING" id="48709.A0A1D2NGK2"/>
    <dbReference type="OMA" id="SREWIGF"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF4">
        <property type="entry name" value="NEUFERRICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="4">
        <location>
            <begin position="166"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="377" mass="42248" checksum="9F89D500387B7327" modified="2016-11-30" version="1">MSRKRLNNTTSSGENSVQMPGPGTPSMFSGEEQLEGYQEFEKRLTPSVDDYNGAIPKEQKSARRPEKIAPKVGKTVIGRVGVMGCAIAAVVGIISVGVLLYGADHTMSFFSKTLWKDKPIDKQHGHDPASVPQKLFKKDNEKLDWKSHLVNVQEKLRKGNSEVRIMTDEDIKYKDGGKMYVVLAGFVFDVSSASKTYGKDSGYHGFVGRDGSRAFVTGKFTEEEGLVPNLRDLTPDENKGISNWVNFYLNHETYKFVGLHSGWFFDEKGEKTWRMREFEEALIEAEALDNAQSETDKLFPGCNMEWNAEHGSNLWCSKQSGGMSREWIGFPRSFKIPDDKTSPRCVCVHPNMLTDPRVSVYKGCDPKSVSCKLGKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHN4</accession>
    <name>A0A1D2NHN4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Abhydrolase domain-containing protein 16A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHN4"/>
    <dbReference type="STRING" id="48709.A0A1D2NHN4"/>
    <dbReference type="OMA" id="THCTQLP"/>
    <dbReference type="OrthoDB" id="6412627at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052651">
        <property type="term" value="P:monoacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006660">
        <property type="term" value="P:phosphatidylserine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054518">
        <property type="entry name" value="ABHD16_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF72">
        <property type="entry name" value="BAT5L PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22990">
        <property type="entry name" value="ABHD16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylserine Lipase ABHD16 N-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="217"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="501" mass="55642" checksum="23E20B23089457B2" modified="2016-11-30" version="1">MSSIKRYAKYIISSPKLYRIYQTQQQYVPPILETISDATITYALPITILLTVYNRKLSYVQLSVLLYVASRILRSLSRLTSPQYLEFLNHVDRASESATSENINVLRNYDFEFKYFPVVHSATVSVQSYVDAQQRESGVLNMLSYAMAHTFGIRLIYPGLILGGVFRSMLEDARAKLVVEKHGKRVKIEAKSEHANVCIDAMVFDNREHGGAGNYLVICCEGNAGEAFAQLLLMLFMLLAHFQFLAGFYEIGMLGGALSEGYSVLGWNHPGFGGSTVRFSFNARLKIKAGVPYPTSELTGVLGVMDYATQVLGFKESSIIVYGWSIGGFPATYLASRFPRLKGLILDATFDDILPLAVPRMPEFMTPLVISTIRNHVNLLNTANLENYTGPLRVIRRTEDEIIADPPGVLNGNRGNGLLIDVVVKRAGNLAPNDIAAVTEWVRQPHDTDAPAYDSLSGANPPGSLEGKDRAIALASSILRDYKSTHCTPLPKEYYRLRQFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI73</accession>
    <name>A0A1D2NI73_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">oxaloacetate tautomerase</fullName>
            <ecNumber evidence="5">5.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Fumarylacetoacetate hydrolase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>oxaloacetate = enol-oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:16021"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17479"/>
            <dbReference type="EC" id="5.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:16023"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.2" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI73"/>
    <dbReference type="STRING" id="48709.A0A1D2NI73"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="6">
        <location>
            <begin position="14"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00042340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="179" mass="19651" checksum="D6EA588579B0F06E" modified="2016-11-30" version="1">MSGNFTRFAELGRKIVAVGRNYRDHAAELGNAVPEIPLLFLKPASSYITEGTPIKIPKGCTSLHHEIELGVVIGQKGTDIPEGSAMNHVAGYVLALDMTARDFQNIAKKKETHGTWPRDLTLLAQLYFTLEPNDIILTGTPPESVASTPVISSKVDLVTWLKLSSRSRAKLVDHKYSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJA3</accession>
    <name>A0A1D2NJA3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJA3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="784" mass="84528" checksum="6BDF78FC768ADF06" modified="2016-11-30" version="1">MNATYELGILSPLSQYLQEGGTQQTSSMGGTPRPGTPRGSGFRLSPDGNLGNPGTPGASHDHHKFPNSPWSGSDPATPGYNRNVVPSSPYISSYPNTPATPGGGGYYQKPNNGGSINGHGTTSVPPGSPWTERSVCTPGPMTPMTPATPMHSTSEQGNGFSSNNGSPTFPEHTINSGKGATLFSGGLVQDALTDALLPVSVVNHNHHNQAPPPPPPPPVSVQNNGNANVALHNNPPYSETERSQAVDHNPNLIKEFEDFLAEFMAGKTRKEKEQDNAARQQQQQQQQPPPQQQNNPPHQQQPQQPLPPHNMPPHMGNGSGMMYNPMPNNNNGGQPSMMMNNPHMNSGQMQSSAGPMRGRYNMGPNGHPGGGHPHPHHPYMMSSNNSMMRSRQVPVHNMQPSNQYTATSAQNHGGMPPHPNSMGGNMMNGNMNGLPPQQQPPPQSQFGHPGHQLQSASIYAPPPSNNGGYVQQQQHQHPQSPMQPQPGNPVGQYMQQQHANNNPVHWQPPPQQMSMNNHNGPPTPNPMLVNNGNMPNNIGGGNNNASRGIPQPNSYFQNPVNSPSMPPVEQGHNNGNNNGALPSFPFNSMSPCMSNNNVAGGTPTNNNQMAINSGTSAMPMGQQQQQMVKTPSQMSLPPTPQTPSSSMPPIEDLNIDLDGPYDGTVLNQTVWNKAAEKASRTNPVIEIGKVLFDEIFTDDEIVYCTLSGRGSTQKFNPNKVHVLKRAVAWLMTRPPRPWEFNVDTCDASLGSDDESGIRGLEKKVFTEYRSRKRGDIMKARNQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJM6</accession>
    <name>A0A1D2NJM6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ancient ubiquitous protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJM6"/>
    <dbReference type="STRING" id="48709.A0A1D2NJM6"/>
    <dbReference type="OMA" id="KFNSWPF"/>
    <dbReference type="OrthoDB" id="1854593at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15486">
        <property type="entry name" value="ANCIENT UBIQUITOUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15486:SF96">
        <property type="entry name" value="LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="357" mass="39530" checksum="637095660F2660CD" modified="2016-11-30" version="1">MGEQMNVEHLFHKSWFRPAGLSTIALILYAPVGICLFVIRVFILLQFFLMALLLPPSKIRQKCLQVMAAVLGMTISAEGDPGPCRGRVFVANHITRLDHLAIHVVTSALKPALDAVPYYLLRPLALTASSLANRTQDSIEASEVSFVVFPEGETTSGEVGLLAFSAVEIPNGINVQPVAIKVSRHWFNTSSVTGGLLNELLIFLFLPNTHFSLRFLPVEVVDNEGLWKQRTQSAIAQELHVTPTKLNTSDKAEFRKKLFFRPPSLAAMARAVQQQLAPQILSPEVILAALQQTGSAEGALEYLRQNRPSAAGNIHPAASTFSKNATHRMMSFQERKRLMIAFARQRYIEKHELQISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKG8</accession>
    <name>A0A1D2NKG8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycogen synthase kinase-3 beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01082</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000020">
        <property type="protein sequence ID" value="ODN05605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKG8"/>
    <dbReference type="STRING" id="48709.A0A1D2NKG8"/>
    <dbReference type="OMA" id="MKTTMPM"/>
    <dbReference type="OrthoDB" id="272141at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007276">
        <property type="term" value="P:gamete generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032436">
        <property type="term" value="P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070507">
        <property type="term" value="P:regulation of microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000055">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000009">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="43"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="367"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="418" mass="46616" checksum="10F4B073747CCE4D" modified="2016-11-30" version="1">MSGRQRTSSSADQRNSISSDGGKVTTVIATPGAGPDRPQEIRYTDTKPIGNGSFGVVYQAKLCDTLELVAIKKVLQDKRFKNRELQIMRRLEHCNIVKLKFFFYSSGEKASKDEVYLNLVLEYIPETVYKVARHYSKNKQTIPISYIKLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDPATGILKLCDFGSAKHLVRGEPNVSYICSRYYRAPELIFGAIDYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFRFPQITAHPWTKVFRPRTPPEAIELVSRLLEYTPSSRITPLEACAHNFFDELRDPNTRLPNGRELPPLFNFTEHELGIQPHLNQILIPPHAAGSSGSNTQTQENSGGNGGGNSATDLIASSEAATATNPDSTSSQPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKH4</accession>
    <name>A0A1D2NKH4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetyl-CoA acetyltransferase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000020">
        <property type="protein sequence ID" value="ODN05615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKH4"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="13833" checksum="009647376FDA977B" modified="2016-11-30" version="1">MSNYFERKNKRGDPCDERCPNPNRGFLQKFIFIFCTATGREAHQKKVVFLPKQVQEVYIGNGFKLGVGKLSSSSNNFWRTSCSTVDCTTINKLEASGMKINNASNINLKCGDQQLMLGGMGINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKX4</accession>
    <name>A0A1D2NKX4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-mannosidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000020">
        <property type="protein sequence ID" value="ODN05616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKX4"/>
    <dbReference type="STRING" id="48709.A0A1D2NKX4"/>
    <dbReference type="OMA" id="GDPPEFY"/>
    <dbReference type="OrthoDB" id="10261055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.110.10:FF:000007">
        <property type="entry name" value="Alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050843">
        <property type="entry name" value="Glycosyl_Hydrlase_38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607:SF70">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 38 N-terminal" evidence="5">
        <location>
            <begin position="223"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 38 C-terminal" evidence="6">
        <location>
            <begin position="787"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1212" mass="137875" checksum="7BCAF11BD1B24A08" modified="2016-11-30" version="1">MEYFFNSESSHVVHSPSTAMPMKIASLLLKPRNLRFIVLTLIAGTLVVAIYHMYYGGMPDTPLPTNPVPADNLVGEIDHNDIDIAPPPLIGDSDYGNGKQEDYKARVVHGNEHDSRPSGSSRDTHQRHQLARGFNYGPTSPASQPSGRSSGRDKCFKIEAFLPDFDASKVYPTLEFDASWITTREYWNADFEKRYQSIAKKDKELKKEKARPSHNLPQTPPLKVFVIPHSHNDPGWLKTFEGYFYAQTKEILDNAVEKLTEFKQMKFLWSEISFLSKWWEHAHPTKRAMLQQLVKEGRVEIVTGGWVMTDEATVNLYSMIDQLIEGQQWVKAHLGVVPKSSWSVDPFGHGSVFPYILQASSIKGMVIQRIHYGWKKWFLDQQKGDFKWVQRWDTNEKYGIKCHNAPWDIYSIKHSCGPFPQICLNFDFRNISGEYSENYLVSSPITPSNVKQKAELMLEQYGRTASMFTHNIAMISMGDDFRFHRSIEWDQQYNNYMKLFDHINANKQLYNNAEVQFGTVSDYFKAPRRDLSSYQGFFVYSDNFQRGLQPIWRWHYSTQPLLKKFYRERKKCLFGARNSLAHLLTLPFHQRGARINKVSNHRQPGNPKQETRILRVQIVELAIRTTDAAVLIGPFTPWSKQNLPHSTDTELKELRAALDRLPFVFQGPNVIKKVVLYNSLGRKRMHLTKIVVMTPDVEVVGPDGQSIISQLNPVLELTENNMIISGQVFEVVFFAELAPLSVSVFELRMAKPNGKANAIRSLVYCKQCTSPGPTFEINTIQTGDIQLNNERLQLLFDRNSGFLLKVTKLKDKTSANISMKFGGYASIDFRSGAYLLMPDTNTEQEIPFRYSANPVKVFIVSGPLYSELSVSHAPLLLSTRLMHTGGDLYEEAIFVQNQVDLGKHNGEIFIRFDTDISSTAKLNHPDYEGSDQPALYTDQSGFTFEKRVKIPKIRYEGNTYPVNTMAYLQEETPNLRFTFVTRCASMEVGRLECMIERRTIFDDSRGMGEGVTDNRPTVSNYVLYLEKLGGNTVVDNTDYQKSLPTLSAHHLSQELSYPSFMYVYNDDKYQPLSGSATSPSQPDVISMLNQELPCDVNLLNLRTITDSSLDYDLNLPSMNALLIAHRFGYLCTTGDCGGSSNTNPNPLSLFYPNTTFNGVQVSSIVQTDLTGVSSTQSYNNFHSHKNLSHLHQILGEPFELTSVLVAFSEIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLR1</accession>
    <name>A0A1D2NLR1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alanine--glyoxylate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00595</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glyoxylate + L-alanine = glycine + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:24248"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="2.6.1.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLR1"/>
    <dbReference type="STRING" id="48709.A0A1D2NLR1"/>
    <dbReference type="OMA" id="YEWDTPA"/>
    <dbReference type="OrthoDB" id="7403325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004760">
        <property type="term" value="F:L-serine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019265">
        <property type="term" value="P:glycine biosynthetic process, by transamination of glyoxylate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009436">
        <property type="term" value="P:glyoxylate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06451">
        <property type="entry name" value="AGAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000039">
        <property type="entry name" value="Serine--pyruvate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000027">
        <property type="entry name" value="Serine--pyruvate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF40">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="10">
        <location>
            <begin position="90"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="446" mass="48744" checksum="BCED017DCEE4BBE5" modified="2016-11-30" version="1">MLKGFVGTVQRALINQRKCYASSSAVLARAYSTRPAADNRRLEIDTMSQEANRKINSVFAPPSVLANPMNVPVKLLMGPGPTNVSPRVMQASSNQMLGHMHAETFQIMDEIKAGLRYVFQTSNPWTLVVSGPGHLGMEAVLVNLLEPGDKVLIGINGLWGKRAVDLANKLGASPIPLEQETGKSISLDEIEQGLSKHKPKVLFLIHSESSSGVMQPLVGVGDLCRKHDCLFVVDTVASLGGVPFFMDDWNVDAVYTGSQKVIGAPPGLSPISFGPRAVEVIKTRKTLIKSYLLDMNELTIQWQCGDPSIPRIYHHTPPVNLFYALREALAELTEEGLENVWKRHAQAAARLHAGIHSLGLKLFVQDESDRLPTVTTILVPEGIDWKRVVQFLMEKHLIEIAGGLGPTVGKVFRIGLLGCNATPEKVDRVLQALKEGLEFAKLQGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMK7</accession>
    <name>A0A1D2NMK7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">JNK-interacting protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Protein sunday driver</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_00189</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK-signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. Syd is required for efficient kinesin-I mediated axonal transport.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms homo- and heterooligomeric complexes. Binds the TPR motif-containing C-terminal of kinesin light chain, Klc. Pre-assembled syd scaffolding complexes are then transported as a cargo of kinesin, to the required subcellular location.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Perinuclear region</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the JIP scaffold family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000004">
        <property type="protein sequence ID" value="ODN06492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMK7"/>
    <dbReference type="STRING" id="48709.A0A1D2NMK7"/>
    <dbReference type="OMA" id="NDNITAC"/>
    <dbReference type="OrthoDB" id="10256043at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008432">
        <property type="term" value="F:JUN kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019894">
        <property type="term" value="F:kinesin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030159">
        <property type="term" value="F:signaling receptor complex adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1770:FF:000001">
        <property type="entry name" value="C-Jun-amino-terminal kinase-interacting protein 3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1000:FF:000001">
        <property type="entry name" value="C-Jun-amino-terminal kinase-interacting protein 3 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1000">
        <property type="entry name" value="arf6 gtpase in complex with a specific effector, jip4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039911">
        <property type="entry name" value="JIP3/JIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032486">
        <property type="entry name" value="JIP_LZII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034743">
        <property type="entry name" value="RH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034744">
        <property type="entry name" value="RH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13886:SF4">
        <property type="entry name" value="JNK-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13886">
        <property type="entry name" value="JNK/SAPK-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16471">
        <property type="entry name" value="JIP_LZII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09744">
        <property type="entry name" value="RH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19056">
        <property type="entry name" value="WD40_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51776">
        <property type="entry name" value="RH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51777">
        <property type="entry name" value="RH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RH1" evidence="12">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="RH2" evidence="13">
        <location>
            <begin position="420"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="207"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="504"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="746"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="54"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="345"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="757"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00082388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN06492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1158" mass="127943" checksum="4224AE92651BF68D" modified="2016-11-30" version="1" fragment="single">MIFFRKSTQVQALAGSIYQEFERMINKYDEDVVKDLMPLVVNVLENLDLSYTENQEHEVEVELLREDNEQLVTQYEREKALRKTTEQKLLEIEDQSEEQIKDLSGKIESLEAILRMLELKSKNAADHVSRLEDKEAEMKKEYAKLHDRYTELFKTHMDYMERTKILMGTDRLENFGIPKKIGNVMSRSTGPVSFGFESLANNSPMLKSLASPGDAPSSGISVLSPGAHLRTGPSNIQEEMSMDEIVDGGNGNDSTPPSSSEHERDREAPIQTSQPQAQHGKSRTKKEERTGNTLYQEFSFQEPEIVEEPTDITGSWVHPGEYASSGMGKEVENLIMENNELLATKNALNIVKDDLIAKVDELTSEQEILREEIASLNAVKSRLKLRVQELEDELKKIKEDLEKKTSNKSDDEEDVPLAQRKRFTRVEMARVLMERNQYKERFMELQDAVRWTEMLRAAKQDPSIDKNKNNRGIFNFFSNLFSKTTTPALTMTTDRLVSSGGIVPHSSPTRGATNTPAQNNSSVEPYRAARNSTEMPAEKLQLRRLGDTQQRRDQTTYSKIKAHVRKDDGRMQAYGWSLPAKAATVPGSAQVANASNSRDAAPSDAALAKVGAPLPTRHLPVPVPIYCRPFMEQAPGMKIFCASGVDLSGGSTKKGELSRACSSPHVWICTATHPASRVTIIDANRPADVILSFDACQSHLLCIAAVPGLKDDDLKPEVGIAETEEDAGGVSAGKCGVLSHVTAASQIEQTERRRSKSVATTDNPSTENESKTDVQETENVMDAKDTESISLVEPVAATDVNEASSERDGAVETEVISGSSIVSEEEVFMSSVQPTMWLGAQSGFVYVHSAVAQWERCLHRVRLPDSVLSITHLRGRVFVSMANGTIAIFRRAVDGQWNLSSYYLLDFGQQPHHSIRCLSVVHDHIWCGFRNKIHVVDVSTLLVKTSFEAHPRKESQVRQMACYGDGVWVSIRLDSTLRLYHATTFEHLQDVDIEPYVSKMLGTGKLGFSYARITALLIASHRLWIGTGNGVIISVPLSESVCILPGHGSIGRMDIANPSKSVYPGAIVRVTGDEKGGRVIPYCSMSQAQLSFHGHRDAVKFFVAVPGAPFSDTHGSMALVGGGVGVEAHSRDGNGSALLKSNSMLVISGGEGYIDFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0T8</accession>
    <name>A0A1D2M0T8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008161">
        <property type="protein sequence ID" value="ODM86580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0T8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="645" mass="74051" checksum="3ACA2038361D6390" modified="2016-11-30" version="1">MGISTTAVGEEVSTPESGSGVASSGGDPEEQPGDDELELSVAETNIEARGRRDSDDDWDSPPPTPAPKERPKEEVDPLSLLPKAEARAIRKQRLKAKNDKISRYWRHKFWGVEPEKIGRKSIAPKKEAVPAQKPILKRSFEDETPADVEEQNLKDKRFWDKYHPQYGTRNSQQSVDEKIWDDQGASHSIKSHAELDLTGKNEEPGKETGGDQKAGKVKIDEDNNRKLNQKPEKVPGTSGSSKDEKYDAANDKKLEQNYKAEKIDELSSPIHPTKHHPYKVVNFDRKGISKSVGELPNSKDGKGGDKFGENEKAGPSGTNKKSEKREGPHKHKMGRLRIVVDPWYERHEPGVYSTEDVKEDLKLSQKQTRCEVKNPEEHEGAEEASHEEPLPYFQWLEEDDQILEVGQDEIRKVGCKCGGETDLEECECGINGEECECKWKENMRMWRRHFKRRLLLRLQLCMRDCEKDLSVAEQIANDVNDLVCESGVCWKNQSFDADGEESEFQSMLELPYDDPNRVWGRTHLERYDGKLYPPKHWSVLEKKWGYDKEKIEEKRGELPWGKNPNYAPWDDEDYEGPWEWQRELMEQEISPIPGVTVIEKEPVYPGPHYHNCNEECVKGVQLEGQKGGRIRTFDLWLMWRESLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1I8</accession>
    <name>A0A1D2M1I8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007078">
        <property type="protein sequence ID" value="ODM86824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1I8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="214" mass="23545" checksum="507BF7B389F5686D" modified="2016-11-30" version="1">MITSLTPPLAKVPESPSSPDSPESASMYEEDSISSTTGISFNIHLPKISGTDSSRRSLRAALEAVPAMPPITNIPIPNMSPPMNSMLPMKTEMMTHTPDEPSGSTFDEILAVLTPSPPQYHMNMNDELNDLLEIAAEEFKIESGVNDEPVIDVVEDPMDPWNSVNSVWEQPLTSVGMDFNFEGLTCRWLILIFSCDLFLNNKIKSKISGKVLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1T6</accession>
    <name>A0A1D2M1T6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006827">
        <property type="protein sequence ID" value="ODM86902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1T6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903382" evidence="1">
        <location>
            <begin position="22"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17571" checksum="28AE25430C805D39" modified="2016-11-30" version="1">MGKLVAILALIAVLTVQKGQADKPWPDWSCYPEFEALAKTHSDKVQTGMEFAKATMEDCKKDDVRGNDCEKECILKKLLTRAVELKTGSSDWTSSGILAHVGQHKDDLFARLTGVFSSAPEIAKKVKDNCYEMSKGITTKSCEEKEAFFQCLDNAWKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M228</accession>
    <name>A0A1D2M228_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kynurenine formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006412">
        <property type="protein sequence ID" value="ODM87023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M228"/>
    <dbReference type="STRING" id="48709.A0A1D2M228"/>
    <dbReference type="OMA" id="DENDWFI"/>
    <dbReference type="OrthoDB" id="7108654at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118:SF12">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="162" mass="18294" checksum="C3060B0079253F52" modified="2016-11-30" version="1">MIDIYDKVHKFKDGKLNVIENYALTQDDVLEWEEKNGKIPQGAVVLLRTGWDSRWGDLKQYRGNKGVGNNSTFDVSSARYLAVERQVLGVGVDVLSVDPGNSKTYLSHRLFASRNIYMLEMVANLHALPPRGFNLWVVPFKIDFGTGAPTRVLARLNNKDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2B2</accession>
    <name>A0A1D2M2B2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006130">
        <property type="protein sequence ID" value="ODM87113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2B2"/>
    <dbReference type="STRING" id="48709.A0A1D2M2B2"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.33.10:FF:000010">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="179"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="328" mass="37524" checksum="A9FFCAE18F8EBCF6" modified="2016-11-30" version="1">MIAKEDLWDFRTNGEYDELMSYAGFERRMKSISLCSSEESQSFHPIANSDWQIFDRLLKPTTIEKRCRNKFFYDEPDFEGNIFTLTTSGGCYSFKSKWRNRISSLDASKPSLCVIAWDNLDCEGSSIRLELTTAASKNKNLKLVDFDKKIKSVNLCSQAQAEDDNGRAIQNPDDYRKLDINAIALEEHNKFRSQHGIDPLSSDEKLQSVAQTFADYLASSDKLYHSSDIQYGENLAGISTQDKETALKEAIQAWYNEISNYDFQNPRYSIRGLKAGHFTALVWKTTTKVGVGMAWNPKRRWWVVVANYSHLGISKELTQKNVFPPVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2F6</accession>
    <name>A0A1D2M2F6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006109">
        <property type="protein sequence ID" value="ODM87122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2F6"/>
    <dbReference type="STRING" id="48709.A0A1D2M2F6"/>
    <dbReference type="OMA" id="PACTERY"/>
    <dbReference type="OrthoDB" id="8055525at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF4">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="259" mass="27635" checksum="65EA28EFA64A2B61" modified="2016-11-30" version="1">MPPSQRMSAVRKTAACTNCLREGHYSTNCSSKHTCKVCNRKHHSLLHVPNSAQAAGSGSSSSGQVPPPTVSTNTASSAQLSQPTQVLLKTALVHIKNKFGRSQSCRVLLDDGSEASFITEKCAKSLACTQPHQCGITGIAANSAANVKWKTTAHLHSYHQEGAVEVELLILPKVTGMLPRVEVDSTQWSHLSGIKLADPLYGNVDLLLGADVVASIMRDGRKYGPADAPLLKTRFWMGPLGKVSTQPHLTICSNVATCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3H0</accession>
    <name>A0A1D2M3H0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_19200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005198">
        <property type="protein sequence ID" value="ODM87482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3H0"/>
    <dbReference type="STRING" id="48709.A0A1D2M3H0"/>
    <dbReference type="OMA" id="DSEYWEE"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM87482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="474" mass="54549" checksum="F41263E89590BDB4" modified="2016-11-30" version="1">MLDILSAILVGLFALFSISFYKVIFSKNSKHLAPGPIRLPFLGNLLQLAWINSKEPQLAFSKLGEIYGSTVSVQLGSVYAVVINSYEVMEEYLTKPEFSDRYFNGWMAERSWNKQLGIIMSKYPHPWTQLRRFSLRHLRDFGFGKRDAMQSVIHAELNDLVHELNISLKENNGIHTFDNYFTVSALNVELFESCNVANSFLFVFPEWRNWFPEWTGMSTQRRIFKEMNDFLQEFVDERKKLGIYKTSPENLVDGFLREMETGDDSEFTEQQLVALMGDFFMAGSETSSNTLAWCIVYLIRNPEVQEKLQKEIDSVVPKGTFPDAEHESKLHYVKATLAETHRRASVLPLGGPRTATEDSYCKQFLIPKGTYIITNLHGIHHDKAYWKDPENFRPERFLDENGKFKSDPRLKPFGFGKRICLGEPVASLSLLQYLTVLVQNFTFYWVPNEPLPAINPVLGITNGPQAFRALIECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M413</accession>
    <name>A0A1D2M413_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_18971</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004810">
        <property type="protein sequence ID" value="ODM87710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M413"/>
    <dbReference type="STRING" id="48709.A0A1D2M413"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000002">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 12" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="11 12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="14">
        <location>
            <begin position="108"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM87710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="245" mass="26889" checksum="5E02782838621AC8" modified="2016-11-30" version="1">MYLSREVYVYKKSISQRDKKKALSLLAVLLSAFAGIGRAATARQARPHSCIKAQCYPTRTSFTRSTSKFLNSQAKLSSLNMTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGALFWSCGLGLSWAFGFHGLGCLCLLWSLGLGWSFLAGCWFWKLVLLAGAGLGASAGLVFERCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M431</accession>
    <name>A0A1D2M431_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock 70 kDa protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18947</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004783">
        <property type="protein sequence ID" value="ODM87735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M431"/>
    <dbReference type="STRING" id="48709.A0A1D2M431"/>
    <dbReference type="OrthoDB" id="5788289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24028">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000010">
        <property type="entry name" value="heat shock 70 kDa protein 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000028">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="457"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="496" mass="55386" checksum="891AF25A1A48C0E0" modified="2016-11-30" version="1">MGDTQLKNDMTYWPFKVAQGDSGPAIDISGKYYPPEEIASYLLKQIVQDASTYLRTPIKKVVITVPAYFTDGQRAATLDAGELAGLEVLEILNEPTAAAIAYKLERFHEESRNVLIFDMGGGTFDVAVINTDSTSIEVLSVDGDTHLGGEDFDKALMHFCLKRFQEQHKVNPLVGNNLGTKTDKDVTKQRLRRLQTKCENAKVQLSFAPETTISVDSFYNGIDLLITIAREEFEKLIESLFNKAIDIVDRVLKDAEISKRDIHDIVLIGGSTRIPRVRELIIEFFDGKALNHTISPDEAVAYGSAVKAAILNGDQSKKMYNFKHIRDVIPRSLGIRTWMFDQEGQFTVIIPKSSKIPAEAMQEFRTKLDNQSAVEIKIFQGEERMADDNEYLGEFILSEIPPAPAGQEVIEVCMRVNNMGILHVTAVCKSTNGSETLIVSENKGRLSAETKKRIAGNKKITKTNKENSDMPTLPHQQSQKKGGILRRLTTFKKTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4G7</accession>
    <name>A0A1D2M4G7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 52 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18819</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004520">
        <property type="protein sequence ID" value="ODM87863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4G7"/>
    <dbReference type="STRING" id="48709.A0A1D2M4G7"/>
    <dbReference type="OMA" id="VFRLECE"/>
    <dbReference type="OrthoDB" id="19482at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007041">
        <property type="term" value="P:lysosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="7">
        <location>
            <begin position="52"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="8">
        <location>
            <begin position="239"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM87863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="415" mass="47196" checksum="4DAEC52D32F03DC4" modified="2016-11-30" version="1">MGDMDPVSLLEEVNPEIEHLVREALQSQGDLRDYSKNIEKDLREAENECIKDYIRESGNIANLHNQIDECDKILEAMERMLLGFQSELGSLSTEIETLQKQSISMSVQLCNRQAVRGELSSFVDDLVVSETLIRTILDSPVTEPAFIEQLKVLGQKAQFVNTVRDTRAARDVIDVIHKLTIRATAKVREYLITQIYKFRKPVTNYQIPQNSLLKHKFFYEFLLGNERQIAKEVKDEYVDTMSKVYMSYFKTYSSRLSKKQSTDTAGKDHVLAAAEEVKGKNPLFSLGKRADLLNELEAPALVPHAWNGPPLPYEALFRSLIFTLVDNACREFLFICDFFLAKGTALMDLFHAVMGKTLNHLLTVIEEGTSSSWDGIGLLLCAHIVLKLQMVTHKRAVPALIFLHCCFRLHLAIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M524</accession>
    <name>A0A1D2M524_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pancreatic triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18659</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004231">
        <property type="protein sequence ID" value="ODM88024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M524"/>
    <dbReference type="STRING" id="48709.A0A1D2M524"/>
    <dbReference type="OMA" id="GMINQIT"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF173">
        <property type="entry name" value="LIPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903479" evidence="5">
        <location>
            <begin position="21"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="6">
        <location>
            <begin position="58"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="6">
        <location>
            <begin position="158"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="315" mass="35130" checksum="53D7682DF9FAFC3C" modified="2016-11-30" version="1">MSAYKSIISTVLFIVASVPAKYLQNTKDVVWFPNPNGDGTLLEANLTPDPDFKIGDVSDVRFHLFTGNNQYTPDELFVGDDVSLTNSHFIPNRPLKVLIHGFGGDYRHTFPWQTYQGYLKVDSNQNFIMVNWTVLADTSNYFAAAQNTRYPPRWVFFGGQVVGQIGSRVSEKLTRITALEPALPLFDVADLHNRTDPSDAIYVNVLHTSGILGFNDPCGTVPEFWEQQPGCGIDLTGGCAHERAPDYFLEALLSETEFRGKKCTSWNDFTSGICDDNEVGVMSYNTPETTTGVFYLRTNSESPYAQAMAKQDGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M627</accession>
    <name>A0A1D2M627_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SID1 transmembrane family member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SID1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003680">
        <property type="protein sequence ID" value="ODM88372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M627"/>
    <dbReference type="STRING" id="48709.A0A1D2M627"/>
    <dbReference type="OMA" id="DANESQM"/>
    <dbReference type="OrthoDB" id="416618at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051033">
        <property type="term" value="F:RNA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025958">
        <property type="entry name" value="SID1_TM_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12185:SF14">
        <property type="entry name" value="CHOLESTEROL UPTAKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12185">
        <property type="entry name" value="SID1 TRANSMEMBRANE FAMILY MEMEBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13965">
        <property type="entry name" value="SID-1_RNA_chan"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM88372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="607" mass="70246" checksum="B51DCE2D9D912C98" modified="2016-11-30" version="1">MNIIQTKKFDNFSKHSTFLSCPIFDREDNIHYGGIYQTITSSGALIVEREKPFLDGFIVVIIAHSDHEQCQRRDPFSLPFSNLFSSSLNHLGTPITITITSNDSNVLTSLQILYWMIPILMAIGVALFLFALLFVRHHFIRTTEFHREERMNTWHGRRIRELCMGNFQHNGNSKRASFCYLVFIVGIFYCIPVIQFALYYYQVSIVTGDSDLCYYNYRCAHPVWFFLDFNHIVSNLPYVFFGVMIFIFVKLHKRKLDKIRPVGESRHDANESQMLVGNDNERNQQVEEQNGNVDDCDGQINLRSQPDFGVPLNYDIFQALGVALIAEGVLSASYHLCPNEATFQFDTCFMYVIALLTIVHLFQSRHPHCFSPNHAFLTIVFIVVPTVFSIVGNFLSSTLITIIMSIFLIITFLVSIYVGFKYGFLEQRQDVHAPMRIVTFPNFKKLFMPGTNIYRLRLVLPAGSYWILYRCPLSTYMLYLLVGNMCWNIVYYIFMKTLHGELTLKGCVFPLLYSTITIGFGVYAITFYFHAAARWELSPPASLAVNQKCLTVLGVEYPFDSHDVWHILSATAIFALLTYCSLWMTTWSLPVKHIFQYFKNARKWCRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M725</accession>
    <name>A0A1D2M725_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetraspanin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_17960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003280">
        <property type="protein sequence ID" value="ODM88722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M725"/>
    <dbReference type="STRING" id="48709.A0A1D2M725"/>
    <dbReference type="OrthoDB" id="6134317at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="25684" checksum="B1B50A1CA5856149" modified="2016-11-30" version="1">MMENFIICTAIIGPFILGIFLVWGAFAVKNGIIWYFGRILDYEGFELANLTIPCILLIVADGMAENIMLNSMGNYYNDGSPSQNVSVQFWDYLQENLKCCGIHGYTDWVAASQAPEIGFIPTSCCMDNAQSSDNVSCTEAITKDKISAVAFITNTIYMDGCLFQYNSSYGIGFLELTAIIAIFCHVCGLITACVCFHQQSVWLQQLDIKFIYYIRFTIVKVFIPFCKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M783</accession>
    <name>A0A1D2M783_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tigger transposable element-derived protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_17898</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tigger transposable element derived protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003184">
        <property type="protein sequence ID" value="ODM88784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M783"/>
    <dbReference type="STRING" id="48709.A0A1D2M783"/>
    <dbReference type="OMA" id="WQMQVEL"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50960">
        <property type="entry name" value="HTH_PSQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH psq-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="HTH CENPB-type" evidence="7">
        <location>
            <begin position="62"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM88784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="515" mass="59011" checksum="2B150DE58DB458DD" modified="2016-11-30" version="1">MSEKVKRKSFSLADKLKIIQKFEGGMTKASISRTMGIPKSTIIRICQDKEGIKSQNVQFNADFKKVRKCQFPKVDSCLLEWFKLQRSRHIPVNGPLLQEKAKEFASLDGIPNFEASNGWLDSWKKRHGITFKLLSGESSAVDTTRVTSWLEDDWPRLRDSYLDKDIFNADETGLFYRLLPDKTHEYKKQTCFGGKKSKERLSVLLCANATGSDKLKPLVIGKSAKPRCFSAIKNLASLPVTYRSNKSAWMTSQIFEEWLRTLDRDMRLQNRKILLLIDSCPPHVAAVTQFPNVNVVFLPVNATSIVQPLDRGIINSFKVKYRSTLVRKIIAKLDDDLDPKIDVLEAIYGMSRAWREVTDVCIQNCFKNAKIIKTCPQLNNDEIEVEEVNEIPLAAIRNHWNLDSFNIQEYAEVDNDVAVFSTPSDAEIYASQTSERMETDVEEPVDATENDFERVTITDRVALQFVEDLKFYLTCNEQCNTSMFTGLENMERWIVQKKVTKLRQGTIDDYFAPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7M4</accession>
    <name>A0A1D2M7M4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003060">
        <property type="protein sequence ID" value="ODM88922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7M4"/>
    <dbReference type="OMA" id="SYLCERD"/>
    <dbReference type="OrthoDB" id="204305at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18902" checksum="B9DE6E8FDA80FBD9" modified="2016-11-30" version="1">MGDPTIDLFSIRDLDSQLSNREAAAVQDWLVVGKAFYLFRDFPGTRNRTVLGGLWGGRNSLIGYDLAKQLLNQLLEKAVEKKDSIWALDRNILGDVVFTPHVTKFVAYDSYHCEYWNKSGNVRPYPTQRQGNDFLGSQVLWKLNKTPPICPVECRPTYGKDWDRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8D2</accession>
    <name>A0A1D2M8D2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002813">
        <property type="protein sequence ID" value="ODM89199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8D2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="25" mass="2821" checksum="FC69F6168565BCF0" modified="2016-11-30" version="1">MKVFASICLSLILCHLGILQSFRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9A3</accession>
    <name>A0A1D2M9A3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="5">dUTPase</shortName>
            <ecNumber evidence="5">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_17127</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01002549">
        <property type="protein sequence ID" value="ODM89555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9A3"/>
    <dbReference type="STRING" id="48709.A0A1D2M9A3"/>
    <dbReference type="OMA" id="CEQEENF"/>
    <dbReference type="OrthoDB" id="419889at2759"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241:SF0">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase-like" evidence="7">
        <location>
            <begin position="210"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="28"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="328" mass="35692" checksum="912DF83086B266AE" modified="2016-11-30" version="1">MQSTDKGSKKYKDAKKLRKNLLAAKAVLVANNATEPSSDSSDETTSDEDEADDDGEEDAVEATTAVTKRKKVQEEQAEEQGEEASSSKKSKKTAKKSKSDEPELSPKKRKVDNTQEEQVEVEKKGDCITKHYAPSDSSDEMHKYYFKGPIGGGYHVAFCQWLKNKQNYIQIRKSSAIGANIPAQFYANLKAAVNDVGVGAAFVKKVTHAFIPFRGSSEAAGFDLLSCHSVDILAGTTGCINTGIQVVLPKNTYGRIADRSSMAIKSLAVLGGVIDRDYTGSIIIMLHNFGRETLCIQPGDRVAQLIVERIYSGEASVLMNGNSLLRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9D7</accession>
    <name>A0A1D2M9D7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_17140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002555">
        <property type="protein sequence ID" value="ODM89542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9D7"/>
    <dbReference type="STRING" id="48709.A0A1D2M9D7"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor TFIIB cyclin-like" evidence="7">
        <location>
            <begin position="108"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor TFIIB cyclin-like" evidence="7">
        <location>
            <begin position="159"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="27409" checksum="3848DB3FCFBA49A8" modified="2016-11-30" version="1">MSRVDFTHAHCRKHPEAPLVEDCRTGDQICGLAVGDRVIDIGSEWRTFSNEAAGTDPCRVGGAENPLLNGSDLTRHIGGGIGTPGLMNLETQNINRGKQSPVEIMIRDGKKLKGRPTDAILSACLYIASRQEGVPQTIKEVCGVSRFSKNEIGRAILFSLGLSNTVRNAATAVAKAAEDLEIVTGRSPLSVAAAAIYMVSQVSKFKRSPKEISKVAGVSDVIVRQVYKLMYSRAGELFPKDFVFFTPIDMLCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9L7</accession>
    <name>A0A1D2M9L7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CCAAT/enhancer-binding protein epsilon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002450">
        <property type="protein sequence ID" value="ODM89676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9L7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="247"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="315" mass="34972" checksum="658931C871A2C1A7" modified="2016-11-30" version="1">MEEDALNLSTKECQPLSTAGSSELDTNNEYRHDSSSSRGHFQSTLPPVITSMPIATESLFSSPPLFAGYGLPSYSGLSYWGGEASGQSEFTSIQNQCDSSLRGQPFVYETTPFMPSHPFATQTQAQLSSLYFAQSKSQQTTILPTSDTNRFPLRAAATYKAETSTNEHSNEDKRNLGTKKQPPPPISKSKRGRKKKAITTPSASAAAPSLSDRPVSALDIDRESRSEQPVPSTSASEQEQSEARKAQVKCQKQRERNKADSKRFRDRKKAKYEEDLRRVANYVAENEKLRSELEAEKAVNSMLRSILYEQGVLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9P6</accession>
    <name>A0A1D2M9P6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CREB-regulated transcription coactivator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002432">
        <property type="protein sequence ID" value="ODM89706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9P6"/>
    <dbReference type="STRING" id="48709.A0A1D2M9P6"/>
    <dbReference type="OrthoDB" id="8947034at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008140">
        <property type="term" value="F:cAMP response element binding protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024786">
        <property type="entry name" value="TORC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024785">
        <property type="entry name" value="TORC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13589">
        <property type="entry name" value="CREB-REGULATED TRANSCRIPTION COACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13589:SF15">
        <property type="entry name" value="CREB-REGULATED TRANSCRIPTION COACTIVATOR, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12886">
        <property type="entry name" value="TORC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transducer of regulated CREB activity C-terminal" evidence="2">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="190" mass="20637" checksum="C69BED55E0C6F74B" modified="2016-11-30" version="1">MLTAYRCPPRPSPQNSPSPFRPASPHDGLSAPPSPSAQPQSADSFYLSQQANALQQHFEQISMVDGTPQRNNNGHWQQGGAMANSGFYVYNNGQQQQIGATAGVTTQQSPSHHQPQTPQTPSSIPDIIFTEFLGSDCTDPLEDFLTSEAAAQAFREGLGPIDTGDFRMLDDPNLVLPDPQAEDAFRLDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA15</accession>
    <name>A0A1D2MA15_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Molybdenum cofactor biosynthesis protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_16908</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MoaC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002381">
        <property type="protein sequence ID" value="ODM89772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA15"/>
    <dbReference type="STRING" id="48709.A0A1D2MA15"/>
    <dbReference type="OMA" id="QTVHMTS"/>
    <dbReference type="OrthoDB" id="429626at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21117">
        <property type="entry name" value="Twitch_MoaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040064">
        <property type="entry name" value="MoaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047594">
        <property type="entry name" value="MoaC_bact/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006870">
        <property type="entry name" value="PRK09364.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01383">
        <property type="entry name" value="cyclic_pyranopterin_phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01386">
        <property type="entry name" value="main_SPASM_domain-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01067">
        <property type="entry name" value="SPASM/twitch_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="17">
        <location>
            <begin position="44"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="379"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM89772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="556" mass="61724" checksum="549B90C2A4FF73C3" modified="2016-11-30" version="1">MEDATASASPRLAPTVKETRNGSRLEEFRMKQDVLPFSAFLTDKHGRQHNYLRISVSERCNLRCTYCMPEEGVPLTPSSKLLSATEVVRVAKLFASQGVDKVRITGGEPLLRKDLPRIIEQLHEMNLKSIGITTNGILLPRLLPELISSGVTAINISLDTLIPQKFEKISRRPPSAWYKVWKGIKMAEKLDPQKYTLKLNCVVQGGINDDEICDFVALTKDQRIDIRFIEYMPFSGNKWDVAKMVSYQQMVDTIRKVYPDFQKLEDPWNHTAKAFRIPGHVGQVGFITSMSEHFCGGCNRLRITADGNLKVCLFGNAEVSLRDAMRDGASDEKLLSLIGDAVQRKHPKHAGMLNLAKMENRPMILIGGHHQLLRSFSTTKLDNNNNNNNPDSPSSTTTSSSLSHVDSRGKAQMVDVSEKKVTTREAVAEATVNLSHETFQAVADNKMKKGDVLTVAQIAGIMGAKHTSNLIPLCHPLPLHKVDVNLELNYERRCVIIRALAKTTAMTGVEMEALTAATVAALTIYDMCKAMGHSITITDIKLIKKSGGKSDYSLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA52</accession>
    <name>A0A1D2MA52_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-type lectin domain family 4 member F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002313">
        <property type="protein sequence ID" value="ODM89868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA52"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903689" evidence="1">
        <location>
            <begin position="21"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18401" checksum="0D8C6DBE8F586E17" modified="2016-11-30" version="1">MKVVIIHCIIMQALFFLSEAAPTNITGDISAELVYLGFVDGKNYFTYEMDQSWFEARTLCQDDGLILASITSDAQLAFLKSQTVHAKIWGHEHWIGARDAQLPRALSYDDTGMEPPTLTGIEWIYRGDDYSTCGAYNPGKSSTTPDPDLIMFPCVFGRPFLCSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAP3</accession>
    <name>A0A1D2MAP3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002207">
        <property type="protein sequence ID" value="ODM90050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAP3"/>
    <dbReference type="OrthoDB" id="8284999at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.15.10">
        <property type="entry name" value="Proaerolysin, chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="32151" checksum="6A40340629A180A6" modified="2016-11-30" version="1">MLVGSKEDQNVTFVSGEHTGIKSSRNYEQLCDPGQAFTGIGVLVDEGGGIKQWGWMCDSVLDPTEMCEPQEFLGFVLQCDNSESGNELECSYSKTIGVGVSTTITETERQGMTFYKEFGYTVETGIPGLSASMSASLGLSELVGYEWSRSDTSTWTKETTVQATMKVRPYAHSKLEQLVVFIDCSLLEKTGKFTFILISPTWEIVGEKRSIVLMGQSGRLHVPNRASNGAVPGKCGGILEISSIGGNGGDGQDGGNGANGKRGGDATSEFPDPTLCKENQVDLEESVVQVELRDRREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBY1</accession>
    <name>A0A1D2MBY1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001929">
        <property type="protein sequence ID" value="ODM90507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBY1"/>
    <dbReference type="OrthoDB" id="10038672at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18073" checksum="E79224BC5F3E04FB" modified="2016-11-30" version="1">MSDLGVNYPCREYTCPICNKRWESAVAWRDSVNSANPAMNPCLQRDSSVSTSTTVNPVCHPQTGKRGGGSTSIVREETPAKAVEGWRKPTKSGKLKWEHRRDLCEKCKRLGRYCKSVPVKPTPAPKVEAWKSPQRTTPAPARRSPPPSNPCGVQVGWLQIMIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC26</accession>
    <name>A0A1D2MC26_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">DNA primase large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_16159</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001922">
        <property type="protein sequence ID" value="ODM90523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC26"/>
    <dbReference type="STRING" id="48709.A0A1D2MC26"/>
    <dbReference type="OMA" id="RINYKPW"/>
    <dbReference type="OrthoDB" id="421393at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009449">
        <property type="entry name" value="DNA_primase_large_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140914">
        <property type="entry name" value="PriB N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0639">Primosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="12">
        <location>
            <begin position="311"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR009449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR009449-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM90523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="540" mass="62714" checksum="293FE1946918B941" modified="2016-11-30" version="1">MEILQTNKRVSTKLEKGFVGGRSRLSHFGRSKQEIVADAELLTAYPTALNFYTTPPTYSISLMEFEKYALERLRLLRLIERVNTTSAARNNEYFYAVIKEINKSPDLPTYSILTSSKPDEDKSDDNLYARKIDHISHFLLRLAFARTEEQRKWFITLEVDFFRLKLWICNQIDEILLQHNLPFVEAKEEARKFNKEILDSSFMMTTTVPGAMRVYKVSFTHALDLVRSRRVFLHKGYAYVPYNDVASVIALKFRSWLSESLSLLKKNIHLVDDDERLQPLITGFERRHVGTDSTAPKNGDAVSVAQLSGFSQKSFPLCMKQLYDVVQKEHHLKHWGRLQLGLFFKRLGLPMDEATKFWRSNFTKRPDIDIGRFDKQYLYNIRHMYGQEGKRADYTPYSCMKVIHSSVGPGDHHGCPFRHSDATPLRTKFVEAGIPQEGIKEILNLVELKHYQIACQRYFEWTHDKNTIEGGVTHPNQYFTESRNILTGKKTIKAEEKIETKRTVYYKSQSTQNAEEKMETTDAPEAMDEDTDAIFAAMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDK3</accession>
    <name>A0A1D2MDK3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ELAV-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001671">
        <property type="protein sequence ID" value="ODM91098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDK3"/>
    <dbReference type="STRING" id="48709.A0A1D2MDK3"/>
    <dbReference type="OMA" id="VEMPEHE"/>
    <dbReference type="OrthoDB" id="266020at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12650">
        <property type="entry name" value="RRM1_Hu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034775">
        <property type="entry name" value="Elav_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="13"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM91098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="9587" checksum="C372CE043F1BC3F2" modified="2016-11-30" version="1">MDQVTVGSKRAKTNLIVNYLPQTMTQEEIRSLFLSIGEVESCKLIRDKITGQSLGYGFVNYHRPEDAEKAINTMNGLRLQNKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDY3</accession>
    <name>A0A1D2MDY3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001630">
        <property type="protein sequence ID" value="ODM91200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDY3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="182" mass="21115" checksum="16963E45C7165A4C" modified="2016-11-30" version="1">MVSNSELTSEVERITGMLQQNPPLLHDLMEKCEKFSDRYTEFIKIRLPPPAMSHPHPIFTELRMEYVRISEVERELNKQYCIFWNKVDDALKLYNYVEKAMKDIGQAAGASGIFSETQFAKLRQLFESDKNYALFNGLSANIPSLLADEWEHLNIIQPLTDCIHRMDTLKAKMNLELQAFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME72</accession>
    <name>A0A1D2ME72_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15365</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001595">
        <property type="protein sequence ID" value="ODM91317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME72"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050909">
        <property type="term" value="P:sensory perception of taste"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013604">
        <property type="entry name" value="7TM_chemorcpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08395">
        <property type="entry name" value="7tm_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="446"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="452"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="493" mass="56538" checksum="A23B33A107C38CCC" modified="2016-11-30" version="1">MKAKFIATNCVINFRDILSIPQEFACDDDDTDAHEQIFLFYSSTLSSPPRIRPGNFFTLGRHNLPLRNFKAMRLLRFKHRKINIISDPIIATKSKEDVRSLLIVPIRINQLLGTFPLSLHKSELALEKSWLSNFFGKTEQVTQLAISSLINLIENVCLVLFLLNRSQIQKFYSEFLKSFVGLLETCYKLSKHQEFNLPLRTSRLHKILGVIFILGLINLGSTWVSCITKSIEVNLGFKKLTTFLIISSYWSLMHYFRLLICYFWICTIMCFQLSFKAVAILAEGHHNDDEHNHNEPRSSIILWVMESFEKLEEFLQEFHSLFGVQLLSMCIIILLPILNCCFELISSVKAEQLGVWEQFTTLVGVVPHLVALVVTFFILCDVSTGMVDEAKGCVTDFRSIRSIDLNGDIQEKARIRLFYISTLSNPPSISPGRFFNLGRHIIPPPHACPGPTSHSPEQQQELVGSQRSAVRQPSPANRQAWPYRNMIKYQNMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME85</accession>
    <name>A0A1D2ME85_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4789 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001596">
        <property type="protein sequence ID" value="ODM91310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME85"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031993">
        <property type="entry name" value="DUF4789"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21177">
        <property type="entry name" value="IP06524P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16033">
        <property type="entry name" value="DUF4789"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4789" evidence="2">
        <location>
            <begin position="72"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="217" mass="24473" checksum="CBD253C643A821FA" modified="2016-11-30" version="1">MSNTCKWISFGVVSLGVVVILVFLYHLSQENNSKCPNEGELMQNDTRECFKRETKGPCFNNLVFVEDKPRSPYGACSCPYMEFNRTIIYYEGQCYFVFSQAYCNEGYWLNVTTHGEPVCELNPCSQQVTQELEAVGVEWVQIKDGRCVQLGKWAEGCPEGSTVRFSRNYVRPSCFQPVTLGQTIGAISAPSIRKCPAGSYLAISGKCQPTMEFDFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEB9</accession>
    <name>A0A1D2MEB9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reticulocyte-binding protein 2 a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001589">
        <property type="protein sequence ID" value="ODM91339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEB9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="65090" checksum="0C50B07A886C7A07" modified="2016-11-30" version="1">MDRGDMRPVIYESFKDLKARRAEQEAYRKALDEQIMQKKLLQQKEREKYEGHRVVPSDPISRNDRKLPNLPSHEGPSFNRSQPPSHPINYGTPPKINDIDNFNEPHPAAVVASMDEFHEKSTNIYPVGGFQQYAIPNNGTVYYSPQQANIPILNKPDSRFVSSASNVSQACLHSQNDIVDASQQPDILPEEYQVVQRPRSVRNSARPTPAPDIPPECMKYIQQVLPGFSVPTPQPQVNKISPKTQKESKTEGQHADSLQNQAFSSCTSSESSSVENVLVETSKKIHVSQTSEQLAGVRVTRKQYKSELQKQIDERKRREEELQRKDQEEEERIQRKIRIDQEKMQKEYEEDLRKQQEKELEEERKRQATLSNQSEFLKAEEELKMKARNKGKPISLQRDVNEDHDITAAPTTSAESLESIGEFFDATLSTILTLIQVPLAFLYDRIIPVVAKRLIKDKIGDKGIYRSETIEQHDYTLCSNEPRNAYNASSGSPTARIRGGCTMSESFALPEPPLPPEVQREMAIRSAPCPSHNDYGGNGLEFLASLRSYLQNEKSELEQRVQAKGSKSTEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEY8</accession>
    <name>A0A1D2MEY8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_15225</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01001543">
        <property type="protein sequence ID" value="ODM91452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEY8"/>
    <dbReference type="STRING" id="48709.A0A1D2MEY8"/>
    <dbReference type="OMA" id="SEINEDW"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="44"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="454" mass="50890" checksum="EE23FA8FF60B1C6D" modified="2016-11-30" version="1">MFKSTMWSAVVNKSTMGWCFRMFFALSFALFASTYASGNGSKQSIVVSTQQGKLEGLISKSRNGNAYYAFKGVPYADYPGRFQVATKFAKWDGIRSAKELGSYCAQIDLLDTSGAFYGKEQCLFLNIYTPTTKKDANLPTIFWIHGGAFAAGSGDDFEGKYFVDEGVIVVSINYRLGPLGFLSFGDDEVPGNIGLKDQLLALKWVKKNINSFGGDPNKVTLAGHSAGGASVHFQILSPQSKDLFRAAISQSGTATAFWATQTNPRDNAIKLASALNCPLPETRSSSTKDTVACLKSKSDMELVAAQVKLKEWYVYPIVLFAPVIEPEDQTVFWWNHQKLFCEREILTRDSISSEIRESYFDRFEIDEFTWQSFRDLFTDRYWLEPLETSIRLQSQHSRVFPYVFRFFGDHSLVHKIYGVSGNHGVGHGDDLQYLYVRTSVVILDIMLCVHTMIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFC6</accession>
    <name>A0A1D2MFC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001446">
        <property type="protein sequence ID" value="ODM91715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFC6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="482" mass="53547" checksum="7B7BF334AD6DADE1" modified="2016-11-30" version="1">MSVKKTESTVPTLHKKSTCTATISTPNEEELGCIVTDLRKPCTAPTGQSLETASEANVPLSSVWKTSQTRLLDETSNLELLKQLKFQHQYLKYCQEQGKVNKNVELTKFISSWVLSSEALLPNSSLYDMVLQPNSQQPLRENEKSSRFTMPRRISREQGKPHKAKSQPLLATLTENRNKTHHLTNSKSIGRFISAKGPPPSAGSSQATIKLQKNLNPRSEKLAFSQAERSSNNARASKSCVTNFSRTQKPKRSISSSSGRSSKIPQRDFVDPFPGKVKITKSSFKRLSSIPAVIGVPSALITYADKQQLQRGFKNAMLGAKKEKSAPTSPNMKRYTPLGENRSGKPQSRKLKSDYSPTRVIKSEKASLSSHFQTMDSFKKADESFLSTVSTAFSGLFRKPNFQELDDLSLKFTISHETLESVQLPATTGRDNNVGEFWLGCDYETERSEYEKPTGEVSFSDPIAIVITVSSTDLPETNHLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFT6</accession>
    <name>A0A1D2MFT6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative chitinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14832</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001401">
        <property type="protein sequence ID" value="ODM91850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFT6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFT6"/>
    <dbReference type="OMA" id="LNIMAYG"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.140.10:FF:000004">
        <property type="entry name" value="Chitinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF359">
        <property type="entry name" value="CHITINASE 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="9">
        <location>
            <begin position="144"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="84"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="35067" checksum="791D894346136BF9" modified="2016-11-30" version="1">MGSLKPSRVGWQKRYMFNGRQFKPDPTDCNKYYVCVNGSYVRSKCSAGLNWNANGNTCDWPSNAKCKPSGTASVESVPPQPVVASTTTTTTTTSATTTTSRPSTTTSRPTTSTTTTAPTSSATTSKPSSQTQYPILIGPNPSAYKIVCYYSSWANYRPGNGKFTPGDIDPTKCTHIIYAFATMNATSYKLEMGDPWIDGPDGLKGYEKVTAFRAKGVKVLIAVGGWVDSGHPKWGHMFKDPYKMQTFIDSCLDFITKWGFDGVDLDYEYPTCPNANCNFDSGVERSGFVALVKGLRLKFGEDRLITAAVSCNENIMREGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGM4</accession>
    <name>A0A1D2MGM4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_14563</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001324">
        <property type="protein sequence ID" value="ODM92125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGM4"/>
    <dbReference type="STRING" id="48709.A0A1D2MGM4"/>
    <dbReference type="OMA" id="XYSCSEE"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17974">
        <property type="entry name" value="DEXHc_DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000726">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF83">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="33"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="222"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM92125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="669" mass="76286" checksum="E20B47F8B26C0F39" modified="2016-11-30" version="1">MPGTKDKKNHKESACQSENAREVFQYPFKEDFIAAVNEYQVLIIEGETGSGKTTQIPQYLKEAGFCDDGKKVGCTQPRRVAAMSVAARVAEELGVKLGNEVGYSIRFEDCTSERTIIKYMTDGMLLREFLGEPDLSSYSVMIIDEAHERTLHTDVLFGLIKDIARFRPDLKLLISSATLDAEKFSEFFDEAPIFRIPGRRFPVDIYYTKAPEADYIDACVVTILQIHVTQPLGDVLVFLTGQEEIEACQELLEERVRRLGSKIKELNIRPIYANLPSEMQAKIFEPTPPGARKVVLATNIAETSLTIDNIIYVIDPGFCKENSYNPRTGMESLIVTPISKASANQRAGRAGRVAAGKCFRLYTAWAYKNELEDCQRPEIQRVNLGNVVLLLKSLGINDLIHFDFLDPPPHETLVLALEQLYALGALNHKGELTKLGRRMAEFPVDPMMAKMLLASEKYQCSDEMLSIAAMLSVNNSVFYRPKDKIIHADKARKDFFVKGGDHLTLLNVYKNWMDTGYSDQWCFENYIQHRSMKRARDVREQLEGLMQRVEIEIVSNPLETVNIRKAVTAGYFYHTAKLGENGQYRTVKHQQQVMIHPNSALFEDIPRWVIYHELVFTTKEYMRQTIEIESSWLLEVAPHYYKSKDLEDSRTKKMPKTIGKSKDELSRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH35</accession>
    <name>A0A1D2MH35_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001267">
        <property type="protein sequence ID" value="ODM92326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH35"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="128" mass="13608" checksum="AD33DD5D2E51C6CC" modified="2016-11-30" version="1" fragment="single">MPMGVPCLLKRCAGQDAASSHLKGSALVAGTSLLGRQGVSMNFSGPVHVHVDNMYMYDESNFAFNSSSSIGKWTDCPTRQPAIQLRSQPRLHESGILRKKGVVSDPAQVSTTGNDNENDGDSPGHPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH83</accession>
    <name>A0A1D2MH83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 2J6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14316</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001251">
        <property type="protein sequence ID" value="ODM92367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH83"/>
    <dbReference type="STRING" id="48709.A0A1D2MH83"/>
    <dbReference type="OMA" id="LINAWEI"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000036">
        <property type="entry name" value="CYtochrome P450 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904032" evidence="9">
        <location>
            <begin position="22"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM92367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="497" mass="56686" checksum="4A7016C88F4FB17E" modified="2016-11-30" version="1">MILEFILACLAIGLMFLFWNNKPPNFPAGPAGLPIIGNLHQLGSEPHKTFMKMREQYGDIFSLKFASYNVIVLNNYKDIKDAFAENAFSGRADFKPLKDRSGGMPRGLIFNVERSWTEQRRFALKSLRDFGFGKKSVETIVYDEITELIDNFRKTIGKPMQTQNKFNAAVLNALWTMVTGNRYSHDDPMLQDLIKRLTSSVTQSRAASVVLFFPWLYQLRNKLTMVFAYAKERQESIAKNMNFVKGTVEDHQSTFQKDAAPRDFIDVYLAEMEKTSDTTSSFYKEEGLKNLTVTLLDLFVAGAETTSTTLSWEFLLLALHADKQEKLHEEIKRVVGLSRLPSLNDRPSMPYTEAVINEVMRFSAMVPLAVFHSALEDVTFKGYQIPKGTLVIPNLFCTMHDPKVWTDPETFRPERFLSEDEKTLVKNEALIPFSTGKRICLGMTLAQDELFLFTSSLFQRFKVGPDPNGEKLTVDYHAASVLVPKPHNLVLYDRIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHA7</accession>
    <name>A0A1D2MHA7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Voltage-dependent calcium channel gamma-8 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001251">
        <property type="protein sequence ID" value="ODM92366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHA7"/>
    <dbReference type="OMA" id="WIMAVFT"/>
    <dbReference type="OrthoDB" id="5917530at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050579">
        <property type="entry name" value="PMP-22/EMP/MP20-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004031">
        <property type="entry name" value="PMP22/EMP/MP20/Claudin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10671">
        <property type="entry name" value="EPITHELIAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10671:SF82">
        <property type="entry name" value="GH19567P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13903">
        <property type="entry name" value="Claudin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="34126" checksum="6FF8199682104680" modified="2016-11-30" version="1">MARSRSNTPPKKSTQVNRVVFSPSSTRNSDNGSINSSTHPKLQSKESADNEKRRRVEKVARAKERREAMLKRVRMEKKVMLFSSIVAFLSLFPVWIMAVFTDHWFNVRQSDEALQKAFNVSLSEQDVFIYSNAGLWRMCHHFQTAGRSRQTCSYFSIFLGRDDSGRSPSTLNEHVIDYTRAQICFAFISVLLMVMTIVAAFYTFKNSRYVYKRLASCLYFMTTITVLAVQEVLGTSVNYADGAKLYPQGSHVSYGFSYYLGWSVFLVYLVNGCMFLVMSRKVKYDDDDDIDGGQIMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHP4</accession>
    <name>A0A1D2MHP4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001254">
        <property type="protein sequence ID" value="ODM92354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHP4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="143" mass="16245" checksum="E41756EE8FA9BEEB" modified="2016-11-30" version="1">MEVLVSIAEKSMLMFVLHIWPMNLSYIKLLWNVNMCKNKIRQRHNPNFHGHHATTKRKKVSFEGAATTNVSGRCIPGQTSRWLKISSQEGLTTLHFTKPWSTSLKEAMVREEDGAADFCGCAVAKHLYIPKRKQGSECLLTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI33</accession>
    <name>A0A1D2MI33_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450 2J5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001198">
        <property type="protein sequence ID" value="ODM92572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI33"/>
    <dbReference type="STRING" id="48709.A0A1D2MI33"/>
    <dbReference type="OMA" id="CDWDSEV"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="341" mass="38464" checksum="C4F4A04EA2C6AFA7" modified="2016-11-30" version="1">MDLFLSISETALIAVLLLIGFLFFRKNKKDPRYPPGPRSIPLLGNVLQLRKDPLQVFQKWAVEYGPIFSIRIGTQDTIVVNDPKLVKELFSDMNSIGRPFNPVTYYVGKGNGIITAHGQVWEAQRTFTLRKLRDFGLLKSSNEQFLQQESDSLIKFFERRVGKPISGIKLFNGPVINGLWRIVSGESCDWDSEVKPEIVERTECILELFELAGKTVEKHSKQLDANNPQDFIDHYLVKIRETTDPQSTFYKEKGVINLETIVGDVIAAGSETSSLTLSFAILYLLLHKEVQRSAQMELDRVVGSSRQVTLSDKALLPYIEAIILETLRLSSIGPLGHPIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIA2</accession>
    <name>A0A1D2MIA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inactive serine protease PAMR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001174">
        <property type="protein sequence ID" value="ODM92703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIA2"/>
    <dbReference type="STRING" id="48709.A0A1D2MIA2"/>
    <dbReference type="OMA" id="EDCTAND"/>
    <dbReference type="OrthoDB" id="7468414at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051333">
        <property type="entry name" value="CLIP_Serine_Protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260:SF136">
        <property type="entry name" value="GH08193P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904085" evidence="1">
        <location>
            <begin position="25"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="19"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="279" mass="30391" checksum="64CC46D97CFA6BF1" modified="2016-11-30" version="1">MGQFGISLLVASFVAIIAICLGAATETGDARLKAPWTAAIFRKVDSSKDQWEFICSGAITGRYTVITSARCVIPRVSGPKFSSRPHHIRYSDLQVVVGLPTSDLASKDQYTQFGTVGQIRDIYDPNNGDTPEGDIAVIRLKNVLNLSTPYVKEVQLLEKPGTLMEAKETKSGEILQLSGYEKARNGVQTRAQSKSSSPLKVSEIKIEEVGKCIEHYTAAYPTFYFNALCGVAVKKSDIIPCYYEGSGLVKKVKDASGAESYHLFGVYSSNTAWQSLKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML17</accession>
    <name>A0A1D2ML17_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-xylulose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12969</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000929">
        <property type="protein sequence ID" value="ODM93717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML17"/>
    <dbReference type="STRING" id="48709.A0A1D2ML17"/>
    <dbReference type="OMA" id="SWKDEIM"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM93717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="27509" checksum="1C1E1CC7F8238FF5" modified="2016-11-30" version="1">MSMSTQTAFVGKKCLVTGAGRGIGRAIVAELYARGATVYALSKNPSNLESLKKDFPNVIPICVDLSNWEEVKKVVEPLEALDVLINNAGINEPCTFLEITGESFDRVFNINLKAVMQISQIVAKKMIERGEGGSIINMSSMCSVRPLPRAGIYTCAKAGLDMLTKVMAVDLGPYKIRVNSVNPALVMTDMTAPVRPEPNEEENEIIYNILQRIPTGVFFVPVSDVVNTTLFLASDETSQINGQCLAVDGGYLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLM2</accession>
    <name>A0A1D2MLM2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000890">
        <property type="protein sequence ID" value="ODM93920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLM2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17391" checksum="8EE6E32344AE5F55" modified="2016-11-30" version="1">MGSPMLELLTNIKGQMEDLISLFKAGERGRQEDYNVSLHNLLEKVEEMNQLSERTEGVVLALEGPKKGLDEGEVAEQQVIEPAKIIWSWNIQVLPDPAIDMMTKGELESGPSSSSTPETSSESITELCARVKRNATATLEDVVMVKVEEQNKGSCIIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLY0</accession>
    <name>A0A1D2MLY0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Soluble NSF attachment protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12762</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000890">
        <property type="protein sequence ID" value="ODM93922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLY0"/>
    <dbReference type="STRING" id="48709.A0A1D2MLY0"/>
    <dbReference type="OMA" id="WSVKEYL"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000049">
        <property type="entry name" value="Alpha-soluble NSF attachment protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="32520" checksum="0183E17E6B43BF4F" modified="2016-11-30" version="1">MSDSEKKGLELMAEAEKKLTGSKGFLSSVFGGGGNKTDDAIECYQRAANMFKMAKKWGNAGEAFSKAAELHLKSANRHDGASNYVDAANCYKKTDIKEAVTCLERAIEQYLEMGRFSLAAKHHQSIAEALEAEGDLEKAIHHYEQAADYYKGEESNAAANKALLKVAAHAAQMENYTKAIKTYEEVGAAALESSLLKYSAKEYFFRAAVCHLCVDILNCQQALERYGDMYPGFQDSREFKLMKSLSASVENEDPESFTETLKEYDSISRLESWYTTLFLRIKKTMNADGELC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMV2</accession>
    <name>A0A1D2MMV2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain fatty acid transport protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000831">
        <property type="protein sequence ID" value="ODM94288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMV2"/>
    <dbReference type="STRING" id="48709.A0A1D2MMV2"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904267" evidence="1">
        <location>
            <begin position="22"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="41305" checksum="774628196FCF8595" modified="2016-11-30" version="1">MYSRLVLLLCLNYGVVVEVLGQNSLGSRLLDLGQHNVFPESVTLSGFSSGGTFAQQLQISYSSLFSGIASFSHAYYRCGPGNGTEADYDNACTIVGNNPVAYDPDRALADIRRYEREGVIERTRNLRNKKLYLYAGSRSSFFNLDQSLGAIRVYEPLIQNIDAIKIRVQDAEQLLPTANFGRACRLNAQNSFFLGNCGFSGAYEALQFLLGDAIKQPPAPLRPNPRNFLRFDQTEFFYGIEGNGDHFMDTIGYIYVPRQCYQRRCFLHLYFHGCLTGREFNGTRHLVNSGYLELAEANDLIVLAPQAVGTGPGGENEIGCWDTYGLTGPNYVATQLGAQVTVVRNILTRILGGDGFQRQNPSQGQSTLNGIGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN77</accession>
    <name>A0A1D2MN77_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Facilitated trehalose transporter Tret1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12397</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000831">
        <property type="protein sequence ID" value="ODM94285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN77"/>
    <dbReference type="STRING" id="48709.A0A1D2MN77"/>
    <dbReference type="OMA" id="MEYTSIV"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000218">
        <property type="entry name" value="facilitated trehalose transporter Tret1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="478"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="34"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="522" mass="57123" checksum="B103C16DBD4AA01B" modified="2016-11-30" version="1">MDCETDTAETVMLPRKEFPDADAKWYQIMAALAVCYICICGGNISGFTSPAIPSMRQVGYREESLCSNSSLLSTDVAASNNSLAERPENMSTCVEMIVEEQVEFLNITDSQASWIGGLAPLGAFVGSMAATISVKLLGPKGSILFLGSPIFLVSWVITALAPSILVVYIGRFIGGIALGLTISAAPLYIVESASVELRGPLGTLTQFLFTFGVLTSFIFGSILNWRQLAWASATIVLPSILMLFLIPESPVWLLSKDRVKEAERAFYKLRGKSADFKSFLECNAKLHNIDVNMNSDGIRSGISFFWKLNKAERRSCLVAIALCVFQQLSGINGINYYALTIFKAASEGSEAFVLNGHVSSIIVASVFCLATLPSYLLIEKVGRKLLLIGSIILMAFSSFGIGIYFFIKEKVEDSGVFRMIPLILLIIFVLAFSSGFGPILYILVAEILSPEIRPIYSPIAVGINWLAVFAITKSFPDLIAITGIYGVFWLYASLTIVAVFFVICFVPETKGKSEREIEKYFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNC5</accession>
    <name>A0A1D2MNC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000800">
        <property type="protein sequence ID" value="ODM94493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNC5"/>
    <dbReference type="STRING" id="48709.A0A1D2MNC5"/>
    <dbReference type="OMA" id="LPPFKLM"/>
    <dbReference type="OrthoDB" id="5861309at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027844">
        <property type="entry name" value="INTS15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14540">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14540:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14964">
        <property type="entry name" value="INTS15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="39491" checksum="F9BCFEEE59ACB06C" modified="2016-11-30" version="1">MNAHMMAQMGENLRWTSFPNNAKDLLGKIEHFYFSCKANNMMWKPEILIDSINQFVYNVVDARDIKRTKLSASQQLQLADIIVNYLSFSGDETDRQALFNSIFYSINFQKGDVPLRILGLVTSLSVAFRKSEILQCIAVWITAASLENPAVLCIAYELSRDLITDEFPDKYQNLPQRSYLFSAVFLIAVGKAYKSIPPPQRLIDQVTVWIENCPRVCFIPPQSAIFEIFRWCAHSEEDQSRLHLALMSAIDRAGKGAQLQVIPHIMTLIQELRVKREHVVSANNNGGLAYAQVERGVDMLFQLIQMLLASECLDRNEIHPIFESSEEALLPRTELYDMLKSIYFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPC6</accession>
    <name>A0A1D2MPC6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11834</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000740">
        <property type="protein sequence ID" value="ODM94846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPC6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPC6"/>
    <dbReference type="OMA" id="YLIRLKW"/>
    <dbReference type="OrthoDB" id="6424114at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF89">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9 11" id="KW-0868">Chloride</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="13">
        <location>
            <begin position="679"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="13">
        <location>
            <begin position="794"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="867"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="867"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM94846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="921" mass="103201" checksum="717F492480077006" modified="2016-11-30" version="1" fragment="single">QRRSLSQYGVTLPDQPDDLSGVHPNDDGYNFFSKGRDFQPRKSKHRFTDDELRTLETFESSAVLPSCSEVYRQWVQRSPKGMNWWVIGTIAIIIGILASVMKLVVEKFQIFYFPFVTKLIVEGSFGKLWIFYPLLGVTFSVLSAIVIVYICPSAAGSGLPEIIGILNGCVVRNVLNFRTLACKIVSCIFTVISTLPVGFEGPMVHIGALVGACMAQPLRCRCCVKNKKTEYDDERSSFQRTCFPKFCRYRDCSERYSLICVGAAAGVAAAFSSPIAGLTFAMEEMSSHWSKTLTWQAFVCCILARSTAELFHSFLEAAESIEEHGGSYLMYLSESALFDMRHVLNLNIAVLIPATFLGLFGGIVGSLFIFSWLKLSKFRRRMLAYINHRPKLVNFVKVFEVLLVSVSIKYFTNALKLSKSYHEALHFTYFQLLSCTAVLLSMQLAICKPVNHSQKLHDSTLSSKHFRLRSFECNNALNASLHDGVLSQTGEFNEGASLLFGSWEQMIRNLFSRRTAGFFNVPLLLYVFGYFLVFATWSSCTSIASGLLIPQLAIGALFGRAMGQIIYDVFGIYNTESGKFDWIDPGALALLGAASFLSGTSRLPVTSVIMMIEMTNDINLSVLIMLCVMLSKFSGDLLTHSLDHSMLDFKCIPYLESELKIYNEGTRINLELFRAEDVMKSPVRYVGVKENVYTLANLLLDTNHGGFPVVQIGFGFYRTFLGVITRLELTKILTKTKKFDASELVGEDIDMIRISYPEYSSGKLKDIETVNTVLNSYSTQIKYRNVHVNLLPYINTSAIAVPRDFSLYRAYMMFRGLGLRHMVVVDRYNQVEGIVTRKDLIGYTVETKLKSVWNNNIRKGFYIGSPTASDRSSATASSTTTSGSPSNPNSIYEVVHRQESMTPHGLQSTVILEEAEDEEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQK2</accession>
    <name>A0A1D2MQK2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospholipase B-like</fullName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Putative phospholipase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the phospholipase B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000679">
        <property type="protein sequence ID" value="ODM95390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQK2"/>
    <dbReference type="STRING" id="48709.A0A1D2MQK2"/>
    <dbReference type="OMA" id="YQEGYWA"/>
    <dbReference type="OrthoDB" id="443524at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007000">
        <property type="entry name" value="PLipase_B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12370:SF3">
        <property type="entry name" value="PHOSPHOLIPASE B-LIKE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12370">
        <property type="entry name" value="PHOSPHOLIPASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04916">
        <property type="entry name" value="Phospholip_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="571" mass="65588" checksum="5417DE2B68F6EDD0" modified="2016-11-30" version="1">MSLKTVAVILGICYLSITVDAIRYKESRSFKKPPHLHSKFAYVTWTKEKGYDIKIFAAHLSAPNGLDWIAKARYQNLVNKTGWAFVEVESKPSWPDEMQAYAAGIAEGYLTKDLIYYSYKNTLENYCDDKPKTCQYIDKFVSQNMAWTLKSVKALKNQNSYWYQVNLLIQQIDGLYFGYKKASNGTESDKLTKKDLIYLNIREELDDLSHALDPTPGLKDPTDREGHCSVMIKVMENNRDIFSSHVTWTKYTSMLRVIKRYNLAYRLSSSDKNPVPATEISFSSYPGVLQSIDDWYITSSGLMVTETTNENYNDDLWKKLSPKTLFSGLRAVVATRLATDGKSWTTIFSRYNSGTYNNQWMVVDYDLFEPTKPLGDGVLWVLEQLPGITVAKDMTSVLRNQGYWASYNIPYFDEIYQTSGHQKMVDQYGDFFSYNNNARAQIFARDHVNAKDVDSTIELMRYNDFQNEPLSRCNCTPPYSAENSISSRNDLNPSNGTYPIKMLGHRPSGATDLKLTNLDLLLLQQFVSIAGPTYDPLPPFRWSTSDFKNLPHYGQPDLFAFEPLIHQWHWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRU4</accession>
    <name>A0A1D2MRU4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heme oxygenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000643">
        <property type="protein sequence ID" value="ODM95621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRU4"/>
    <dbReference type="STRING" id="48709.A0A1D2MRU4"/>
    <dbReference type="OMA" id="FTMNDIA"/>
    <dbReference type="OrthoDB" id="652091at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720:SF0">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00088">
        <property type="entry name" value="HAEMOXYGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="357" mass="40538" checksum="E9D3A6093E24CC17" modified="2016-11-30" version="1">MAAQFPKVRRRTVEEDVIIRELSEEERLQNAVNSTDDEDNDPDEDDEVLFTIKMRQATRKVHNVSDALVNAKLGIAMSDEKVWAEGLLVFYEIFRFLENALERLAPRNSHFKKMHAVIQDIQRTKAFEDDLQYYYGNNYLKTYQIRPSVADYLKHLETLEEREPLRLLAYVYHLYMGLLSGGQILKRKRELRRKLKRSFGELLGWFGLRPQGSTTDSYGSSSSKPGNAVTTFAMDGRTISDIKKEIAFTMNDIAADLSRDEKESLLSEGIAVFQRNNEIVGSIERTGLIALKNLTGSPVIWLVALVAIGTFCMYWYFSEASPPPLSLPVPISPPPADSIDLNPVDTEFEIGADGFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS33</accession>
    <name>A0A1D2MS33_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DnaJ homolog subfamily C member 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_10755</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000606">
        <property type="protein sequence ID" value="ODM95919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS33"/>
    <dbReference type="STRING" id="48709.A0A1D2MS33"/>
    <dbReference type="OMA" id="RANHEES"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000046">
        <property type="entry name" value="dnaJ homolog subfamily C member 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="299"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="213"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="334"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00074367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="557" mass="64031" checksum="E95BAB4D8EFE67FD" modified="2016-11-30" version="1">MAAAKTKKCYYDVLGVERDATDDEIKKAFRKLALQLHPDKNPDRQDEAKEEFQKLQQAYETLSNPQERAWYDKHRDAVLREGFEQEDDDFIVDLFPYFTSACFTGYNDEEKGFYTVYREVFELISTEELDAGCEEDIPSFGDSLSSYDDVVGPFYGFWECYCTCKSFMWKDEYDSRRAGNRMVARMMERENKKVRAEAKKAWNQQVRALVDFVKRKDKRVQEWRAQQEVLRKEKEAAVAKRMQEEKTKKLAERKKALESLKKEREKEQQKINVHIKEMAGVYGEACSEEESDEDEISCLYCAACNKSFRTEKAFANHEKSKKHLAEVERLREELGEEESEGEEEEDLDDEDIENESVTEEEEEEEKQDHNEQNANVTNKASSVDGDIDEDVDQIANGVDNLTVEASEEPEDHDEPNVASFVAHSKKNKGKYRNAHMSGDSHDESAPLETLAKEISDNEAEAASKGSKKKRRRAKKGEISAENVVEKNDEMEEPKSADNTPAKCIVCNQDFPSRSKLFRHIKSTGHAAPITVVEAKAKFNAAESVKSSKKKKGRNKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS62</accession>
    <name>A0A1D2MS62_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000605">
        <property type="protein sequence ID" value="ODM95927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS62"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="82" mass="8887" checksum="6F1D7EBB3F9B044A" modified="2016-11-30" version="1">MTLTSFPGAFFLVSAAITVPVLLIFAWFYWQVRKEQSEDLKQSLADEGETGGGGDILNLDDGGDSTDSEASGTATPEHKERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT85</accession>
    <name>A0A1D2MT85_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vitamin K-dependent gamma-carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_10775</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000609">
        <property type="protein sequence ID" value="ODM95905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT85"/>
    <dbReference type="STRING" id="48709.A0A1D2MT85"/>
    <dbReference type="OMA" id="TYLNHYY"/>
    <dbReference type="OrthoDB" id="206689at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008488">
        <property type="term" value="F:gamma-glutamyl carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019842">
        <property type="term" value="F:vitamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011020">
        <property type="entry name" value="HTTM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053934">
        <property type="entry name" value="HTTM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007782">
        <property type="entry name" value="VKG_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053935">
        <property type="entry name" value="VKGC_lumenal_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12639">
        <property type="entry name" value="VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12639:SF6">
        <property type="entry name" value="VITAMIN K-DEPENDENT GAMMA-CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05090">
        <property type="entry name" value="HTTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22777">
        <property type="entry name" value="VKGC_lumenal_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00752">
        <property type="entry name" value="HTTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="HTTM-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="625" mass="72091" checksum="9E886E4C1DA5AB39" modified="2016-11-30" version="1">MALDVFQERGLSDADIRFGDPNYCFFPLFEWIQPLPIQQACILYSIMWAGSIGIMLGLKFRLSCLLYLCPYLYFFLLDKSRWNNHSYLFSLFTMLLTWSGAGQHMSIDALSIPKETKLSGVPKWNYFILKFQIFLLYFYAGVKKLFDSDWINGYSMKNLSKHSVFSPLKLVTDAETIEFYMVHMGGLVYDLTVGFMLNFDFSKKAAYLLSLMFHGLNSQIFHIGMFPYVCLASLVLFCKPGEFPCSLFKTNLEQTSSKSSRLTKRTKVSRNESSSPCKSSSSRATTGLLLFYMLLQLVLPFSHSITQGYNTWTKGLYGYSWDMMINSWETLHQKITVRNYYTGDERYLDTDVWVTNDRWSSHPDMAKQYAGCISRNLARFNITNIEIYMDVWKSLNGRFQQRMYDPRVNILTAPWSPFEEVTWVLPLLRQFSHYRQDHFQRIAKEVSNWTESSDVIFVADFPGLYLENYLPKELGNVSITVLSGQIMIEQDGDPNITLTNTMSAGNDGSAVDDSSNANNGDVLISTKHGIRSAEFHKVHVVSFPNPSCYMYTYTNDTAEKLRRTKTSEENDGESSIISQIWKEIREFAHEKYQEFSTSIYLVANAHLNLFFDVPMVLRKSINSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT96</accession>
    <name>A0A1D2MT96_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000593">
        <property type="protein sequence ID" value="ODM96014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT96"/>
    <dbReference type="STRING" id="48709.A0A1D2MT96"/>
    <dbReference type="OMA" id="CIWNNIV"/>
    <dbReference type="OrthoDB" id="5983145at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038838">
        <property type="entry name" value="TRIR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34753">
        <property type="entry name" value="TELOMERASE RNA COMPONENT INTERACTING RNASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34753:SF1">
        <property type="entry name" value="TELOMERASE RNA COMPONENT INTERACTING RNASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="351" mass="39103" checksum="D91FDEE9950F39EA" modified="2016-11-30" version="1">MPNCIWNNIVQISDHKALKVETHLFVLKMDRNAKGQYQSNQYHGGGGQHQGNNAPYPWAQNGMTPMYRGQSPPSAHPPRPNDRNMYYNQAQASHPAPPQNAGMSNHSYPNQQSFPPVGPPPQYGQQMNNPWGHYNQTQSYNNAAVTNAPTQAPAGQSYNQFMYPPPPPPTAVNNLPNQNQQNMPYAAAPPPPVHSYYQMQQPNYYYPPNQMYPTAVPPPPLPPPPVAKPEMSSSSENSSRETSVSSDSKSTKSSSSSSSDKASNSKKDMKSQPPPTEEKEKEEKETKKAVPIMVGKRRGGRVLPTGVVKKQKVEDDSKKGKSDAWSQYMAEVRRYKDQSCTEERQNRPLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTD3</accession>
    <name>A0A1D2MTD3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-glucuronosyltransferase 1-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000588">
        <property type="protein sequence ID" value="ODM96054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTD3"/>
    <dbReference type="STRING" id="48709.A0A1D2MTD3"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="69" mass="7932" checksum="3464748750EB8E3F" modified="2016-11-30" version="1">MGSDQDWNMAQVEYSGIGLKLELSDITEESFSKLLEIILNDPRYESEVQRRSTLFRDRQNSPLEKAVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTF3</accession>
    <name>A0A1D2MTF3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Armadillo-like helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10702</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000597">
        <property type="protein sequence ID" value="ODM95975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTF3"/>
    <dbReference type="STRING" id="48709.A0A1D2MTF3"/>
    <dbReference type="OMA" id="YEATHLN"/>
    <dbReference type="OrthoDB" id="2012278at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039868">
        <property type="entry name" value="ARMD3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013636">
        <property type="entry name" value="ARMH3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13608">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13608:SF3">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08427">
        <property type="entry name" value="ARMH3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01158">
        <property type="entry name" value="DUF1741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Armadillo-like helical" evidence="5">
        <location>
            <begin position="411"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="662" mass="75447" checksum="EAC2534E8152B367" modified="2016-11-30" version="1">MSLRKTSAHSLGKKQLKEKIIQIYEQLLQGEDPSLANSNFWDEFFLLKPKPSVLETELSKLRGDQLNYLKPIIRSLFTHCVSVLGETNSNSHHIKICNSFQTMVGLVDGVVKLIKTEFGYDLLDALMGFESATRVINDLLNNSSSILTGEYPKCVKQTCIHALLMIMTSTEIISKNKIMEYIVTNQTFLESIFWLLSQTDTRIEFGHDCLIIVTLLVNFEKDRPNDCAVRLSLVDDHLTLNGYSQAITGGLSEFCMQHTLSAESNSGWLHSFTSMVGSMFITDEHGKNESLCGTKVGLLVAFYEAIHLNRNFMTTLANTKTDTSPCNTLSQNVTSPMQMPPSNLLVTFLEYSSIVMQDIKTESSSNLVKLCFIILTCIAEDQYANALMSDPHLVFRVQIHRVPMRHRKISQDLSPPMPLVCALLDLMVEFLMTHLTKRLPYDIYMQSVGIIHRLLCYQKKSRTKISYDWRQLWSAFFTVLKFLISNEASLLKKFDIFQLALQIVNMVNLFITYGDTFLLTAASYDELYYEIIRCQQTFECLYSLTARYASNSGDYQSSASKLSFALVNVRAILTHFSPKIDEFLTSQNISTPTEEQIIEVVRENYESLTLKIPDSFDQFERFSEVPKYSSFFTSIIRVVIKDTRYNLSGKQIDYSPILTGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUR2</accession>
    <name>A0A1D2MUR2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abnormal spindle-like microcephaly-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000514">
        <property type="protein sequence ID" value="ODM96662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUR2"/>
    <dbReference type="STRING" id="48709.A0A1D2MUR2"/>
    <dbReference type="OMA" id="DPAMKEP"/>
    <dbReference type="OrthoDB" id="252964at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10699:SF11">
        <property type="entry name" value="IGLOO, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10699">
        <property type="entry name" value="NEUROMODULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="167" mass="18385" checksum="9BD7BDC515E11C76" modified="2016-11-30" version="1">MGDELTGLSRVHFANRETGDDKAENDTGDLNLDDPELEKAATRIQAAFRGHTTRKTLGKMAEGEEVIDIDLNDPEVGIAATKIQASFRGHKARREAEKAEKAKATDGELSEELQKLKTTEEKPAAEEEEDLPDLNDPEVNKAATKIQAHFKGHLVRKTLKDPKDASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUT3</accession>
    <name>A0A1D2MUT3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000538">
        <property type="protein sequence ID" value="ODM96465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUT3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="400" mass="46996" checksum="7E8C1D2F30C178ED" modified="2016-11-30" version="1">MKSYAQATTDKPRNDKQLYEQFLQFQNYLLSQNIMTDSDSTNMGCKWRDKLHRINDTRFFIYDTIGRKDIEANFTTARAFCEALNEKGLPTGKWRLARIEHLTTFRMITRKMEEVAKGASQHNNEVWIDAFFNYDTNTFQDSDGNILKFNSVLLYRHYKPMGIGAHEKHDDKVYNITKDKPNFQQCLTLSLPWPNEAEKGNYKGMTFGHQASFEERACEATQKFKPICENLQPECRYSEDLRNFNYFPIEGYAQKSYVDDGVWVFANRRFLVNLTPRNKTESEKFCESIKTKLYTPRTDDTCLIAYLKLWNIHLTHLHFWTTIKAKYTGLGTKDKAKEKDYQSRMSYENGTDFTLHRRNKVAADKLTLSDTARVDWIEQNATLMKIFDNLCVTANWAYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV97</accession>
    <name>A0A1D2MV97_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Neuronal PAS domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_09764</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000489">
        <property type="protein sequence ID" value="ODM96916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV97"/>
    <dbReference type="STRING" id="48709.A0A1D2MV97"/>
    <dbReference type="OMA" id="AYWSHHH"/>
    <dbReference type="OrthoDB" id="9978016at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010557">
        <property type="term" value="P:positive regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000081">
        <property type="entry name" value="Dysfusion, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23043:SF39">
        <property type="entry name" value="DYSFUSION, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23043">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14598">
        <property type="entry name" value="PAS_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="103"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="639"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="723"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="770"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="382"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="723"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="800" mass="84918" checksum="716E232246161413" modified="2016-11-30" version="1">MNMEDLLIHGDSVYDIIDKADHGTVQSELLRGGTSATASQNPPGEDTRIFLCRMNVSRNARRQMRFGDQKVVLLQGRYLSYLPLCSRNEPVFVAACTPVAMPETRECVVQGATNVFTTIHAMDMKFMHIDRNAEYYLGYTRSELGGISWYQLIHWNYMREAQSKHRLISQSEQEKSCILLLRLQTRSGGWIWVHCVLQVKDASDSSSSSSSSAQQQQQQSQQTPSQQSVIVATNQILSEREAGVMRANSWLYHYYTVQTKLQYGLAYPEAVAASQGSPAAAATAAARLAAAAYFPTPQLMNYTGHPHHHLHHPHHPHHAHHAHHQLTSAVETAGGYAAAAAAAAAASMPPPLHSPAHNGTGTSGAYGSGVATAGHPGYLHPHQPHHHPHPHHPHHSPFEMSSVGGAAGKDSPLDFSLAASTIPFDYQMSTGSYGAAAAYWSHHHHHHPHHSSASHGYTAPPTGSGGTVGSQRSTGSEGSPSNSSIVSASATSPHTWSLQQNGVTTNNQASSSVLQGSPPVKGSGSTSVIVNGNTGNSSSSSGSSRKRAKKENIVTAPTAAVVSDPTSPPLTSKSSDRPSRSSSHLGGVNPLSNGIDRSDIGGSGGGGVSGADCSVATATTPFPYHNRYRNAYKIFGSSTISPSDDDQSQMKEESSTMSCPLTPSPVWEGQTHRVPDLQFYNVERDAAGHHGVMTGTDLIHCVPTYQPYLSYCTTPVTAASISAHHHHNHHPHHHPGFGGSNTSSLGHVNGTTNLGLGMGLSMGLGSANGGLHMGTSLSESGSPNKENRLPPTPESDNGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVW5</accession>
    <name>A0A1D2MVW5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09613</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000475">
        <property type="protein sequence ID" value="ODM97071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVW5"/>
    <dbReference type="STRING" id="48709.A0A1D2MVW5"/>
    <dbReference type="OMA" id="PIVFIQH"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000021">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904621" evidence="7">
        <location>
            <begin position="22"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="8">
        <location>
            <begin position="57"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="8">
        <location>
            <begin position="453"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="766" mass="86266" checksum="16E5BA95AE737AB9" modified="2016-11-30" version="1">MTNFIKTSLIALIGLIGASSGFTIHDPESFFVDNALLLEENNGFTPFSDHEDGNLTVPQIIAKYGYPVEVHNVTTADGYILQLHRIPYGRNCGPAENKKVIFVQHGLLCDSSNWVMNGANKSLAFRLADACYDVWLGNARGNTYSKRHVTLDPHLDKEAYWDFSYHEMGIYDLPANFDYMMELTGTDGLYYVGHSMGTTMFWICMAEVPQYNSKIKLMNALAPVAHTEHMISPIRLIAPFSTQIEWLLKMFGLHEFLPSNDFLELISQQICDENSPIQPICANFLFILCGFNPDQLDTSLLPVLLGHLPAGASVRTVVHYAQGVPSGEFRQYDFGTEKNMEKYGQPTPPDYDLTKITAPIALYWGENDWMGAKADTLRIAELLPNIQRMFRIQDELFNHLDFLVAKQIQELINNPQQSTLLLLGLLGLVALASSKSLQNYNPLADNEDAKLSVPELIVKYGYPVEVHNITTADGYILTVHRIPYGKKCGPGEGKRVIFLQHGLLGDSANWIIAGPEKSLGYNLADECYDVWMGNYRGNTYSKRHVALDPVANKEAFWSFSWNELGTYDLPAAFDYVLENTGTDGLYYVGHSMGTTGFWVCMSERPEYNSKIKLMNAYAPVSYTEHMLSPIALIAPFSGQVEELMPTILGHVPAGSSVRNLVHYAQGVNSGLFRKYDHGRAGNLEAYGQETPPEYDISKITAPVALWWGENDWLGVKSDVYRLAEQLPNIQLKYRINHDKYNHLDFLWAKDNVDLINKQTIEFMKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWA3</accession>
    <name>A0A1D2MWA3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DmX-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000461">
        <property type="protein sequence ID" value="ODM97221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MWA3"/>
    <dbReference type="OMA" id="AENGNTC"/>
    <dbReference type="OrthoDB" id="342131at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022033">
        <property type="entry name" value="Rav1p_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12234">
        <property type="entry name" value="Rav1p_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="RAVE complex protein Rav1 C-terminal" evidence="4">
        <location>
            <begin position="1051"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="2522"/>
            <end position="2543"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="2635"/>
            <end position="2676"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="2677"/>
            <end position="2711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="159"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1055"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1494"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1542"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1821"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2049"/>
            <end position="2069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2161"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1077"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1543"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1821"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1855"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1876"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2161"/>
            <end position="2182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM97221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2767" mass="309397" checksum="A18CC53FEA27E30A" modified="2016-11-30" version="1">MVSQVLRSSLNFYNGSEGLKPEGVRKIIIWCFTMFTTPITTLLACFHLKKHRHKEAHSITSAFPLPMTMSSLPMMGLPMMATHSIPSAMDLMQNHALMHHGVAVHFHLAGSINAETDIPLVPPLKHHNFRVFWLNNKEMFFTQKSELILQEICRKGVEREDSGDGFGHDGSKRSGIPKSNSQDDASQADDSSQPSLSSAASSNSLAEGMWTEGFGDLERKLESLMRDWQRTPDVLVSLHPIDGSFLVWSVEWLDEYMPGCFRQAQVSFSSCIPGAIPLADATSMSSPNLYLFPLEKLAANRAGMMTKHHNGSLNLWTLSFGDDSKFCQVMSVAHAKRASGHRFQVREMACHPVLPLVLTAASHAFSTYSAIDETDSDQKQHHQNYCSELILWRVDPIGPLCKSGGVVEVARINSSELDAFSHVAWVPGLLPSTSLFSNSGCFVASDGTNLRVYQAVLDASNLLAEISTAYRKRKASLNDSVVSLSSSSSMSSIHGVLEDPDPDLFAIVSQQSTSRPGCILQLDRIDNQNWGEVSFIQVFRDDLDPTRRGGAEKLPSIITTMEKSNKKSFLNISISKLFEQTVCPGLDVSFSACSGHFVCGSSYALISTSKESVKLWKLARNDGAVTGVEDNYELCFKECNTLAACKEKGQMIQASAAYSGRIACVYKMDRETKDRNLLDEDKDLDANAEGQPVERCESCAITVYECESSGGTDWLLEDTIELKTDEEVTAVHLEWIPKHDAQHILALAITDMVCLFAHVSREPSVTFGAKVLPATASCKSQYWLPLHAFKLSSADGLRPFPVRFGWIHAVCVVAMRNEMQVYSQWALENLTDVSTLLPSTSQFNRQHTEIGEQSNRPHIELSLLSGSVGLFQYTRHCYPVLPQYHPSQLLEMLNSGKARWVRVILAHLVRYAYNFYTLETLASALNERKCQRVNFNFRCLGGGAGSLKRQNSLLHDEDGRQRSYSRSRCLSVSYPGPTSPSPLEHRNSMIFQPEDLSLNYAEMRTIPPVPLWMLLSAEKETSQPLSEDKTKDYNDLFNMETTEEPLDESVFDDFVENDDEDGMGTGTEGRKRRRSTSGDNQPLTFGQRQSRQLSRVLTHTQLPGLTSLDQMHLLALADTVAAIGTRLDHRDVQQSHIHDGTPDSLDECGLRFLIVVKQYTYLVRCLPPAQRVQLQKQGISTSDVVWAFHSESQEDILNLIPAYQKGNMTWQQLREIGVGWWLRNNQTLRLCMEKLGKHAFQREQDPMDAAIFFLAMKKKTLLWGLYRSNRNTKMEQFFQNDFSQERWRKAALKNAYALLGKQRFEHAAAFFLLSGSLKDALEVCLSKLKDIQLALVIARLYDGGDLDPIPPSVKNLLQTEIINPRPGEVGEAERDPFLCSIALWMLKEYQSSLDILLETKMSSRIFNFYVFLRSHPLLVRQNKAKGTLALNSQERRLYFFTAHEHYAAGCPTLAIHVLSQLPKAYQKLDSKLGSPIKPMKTLDSQIESGIITGFDETDHTPGKLNDSGTGTSLLDFGPKETKKDNTVDFDWGSSALSSKKADDDELKLDWDDDENSEDENKNSDEAVVVNHRDSLQKSGKNLLNNSVSKDEDSVAVEDLEEDLNDPQTVIAVELKLASCLKLMSEEIVSIAGQLEGTELRLHLYAWLEKQVPTLKELCKYQSDDDEVIDDEWNMRDRSLTPKLDTHSSGLHDILLSEKLDLEWKMGVITRRSRWLKANRHLLATLLAFSRLHAHALAPVYIELVFLLDELQKEKSSGTGPSLVSPLPFLHSEFPLLSAVANPTKTAVSFIQSSARDILHTICELIAAPVFPLPKDESQLNRKQSVAESSIRSHAAKSEDGLEDEEVEESKKETDADADELNEDEINNASDGSPIKKSSDLHEEGSEVSEESKEEMSAVVCDWRVVLVLRDSAVALSACLFQALSDSEGETTKDVGVSLLYAPRRRRWSSSGTGAIDGIGEKVISTPDKWPGVSILRGILSREEDGESPKLKYLLVECYAAVFSSILVHSIAICDAKAIFRLLAKKMDATAFSSIFGGGTKRQIKLPTVHQLHPQTHSTSSDKDGGDTSPSSVWTTFASLNKARMKFNMKLLGQQFTLTSPRTPTASAKARMFVVLFSAEERPSFREKFVPPEIPIYGYLLGKPNKPRLDSETLDGHVTAVDSEDEEDIEEEVEDEEEEDDGMGWEPKMKTNTNTTRINEGEDPFSYSWRLMRLAAVKLARKELERIVEIAGIDAAELSHISPFLDGVMRVFTVWKQQLFNELEAVSPAPLNYLQNATVENLSGPPIHKYRALLEPSNTPFLSKKSTFGLRRLWTFLVREEDVQNYFIRFVFGKKRPEDTFSLFGDMTYDGRVTKKEEGTGTGEESEDECIPAGPVRIVHKDHESISAFCLNQSGNGLMALATPKEIQELDVSVLLQMESWKFEDQFELDLINLYKDPETLSNSSYLVVQSPSDRKILENVERPQKGSHSLILKHRVDGVRRMASHPTLPLSIVNQQPYHVSNMISLYLTDIAFYSFYCQTDLSGSQDGSVRLWEFSHAQPVAVPRPPGTFAKVNRIRFHGNKFGVCDGDGRLSLWQIGANPRPFYTVQCHSKQTSDFVFLGSSSLIASGGISTESKNVALWDTLMPMKKAQIASFTCHEQGCVALSYSEEHQSLISAGKKGAVCIWDIRQRSLRHRFQGHESAIKCLCLDPSEEFFCTGAADGDIKVWDFNGKARAVFPAEHSRSGFFKNIPGQGVTQLSLEGSRRLFSCGADGSVKIRLLLDKFMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYY6</accession>
    <name>A0A1D2MYY6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7042 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000378">
        <property type="protein sequence ID" value="ODM98151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYY6"/>
    <dbReference type="OrthoDB" id="9979716at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055470">
        <property type="entry name" value="DUF7042"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255:SF9">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23069">
        <property type="entry name" value="DUF7042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7042" evidence="1">
        <location>
            <begin position="55"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15778" checksum="5DCF4A4CE9A63885" modified="2016-11-30" version="1">MHETKASVAVASLGSNQININVSSYCEEKNTLENLCSQIPGDAQLYSLFRIDAQPEDCPFKGAPFTFTYNRGHGECKNPVSFVDTCTEPSRLLLRYQACPDVQKTESTGRYAEFQEQSSQPGDILGKWLEIVEGSEESCNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ80</accession>
    <name>A0A1D2MZ80_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Clotting factor B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000362">
        <property type="protein sequence ID" value="ODM98353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ80"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ80"/>
    <dbReference type="OrthoDB" id="546450at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904753" evidence="4">
        <location>
            <begin position="25"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="89"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="353" mass="38694" checksum="74B67D13C8651F76" modified="2016-11-30" version="1">MKLSLKAFCIFIAILFSLSSKVGGRHCLQNGTVSKLQNGTEQLEGSNGSALLFSSTTTSSTPPTTTVPFFEDVSSACSCGLAEFGTGKIVGGTNVDDAHLWPWFAVVVRSDRPTVGSHCGASLISSRYLVTAAHCLLPMIHVGLRHFKVKLGYTDLRQNATEGERLDMAIESVTIHPRLRFEQSYPYHNDIGLIKLAYPLTCKYNKRIRPVCLPPSPSDEEEKNHFVDQVAITAGFGRTSINGNQSLTLQQIKIKIISNKECMSHFIQLPFQGPKILRNMLCAWKKGHDSCVGDSGGPLFLKPSNSSKYIQLGVTSFGIGCANEKYPGVYTRLSEYLHWIRTVAVDLSSASPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZW9</accession>
    <name>A0A1D2MZW9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000346">
        <property type="protein sequence ID" value="ODM98530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZW9"/>
    <dbReference type="STRING" id="48709.A0A1D2MZW9"/>
    <dbReference type="OrthoDB" id="5977743at2759"/>
    <dbReference type="UniPathway" id="UPA00885"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11141" checksum="80B475A42D1FB9DE" modified="2016-11-30" version="1">MELSVVHNSQYPKASGTLSLSTGQRQPVDAESGIDGDDPIISTGFMKSRWNELVSLVRITGVTYRLTQGVVKRIIPAVASTNAVIAAACATEVFKLATSCSIPMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N196</accession>
    <name>A0A1D2N196_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Bromodomain adjacent to zinc finger domain protein 1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_07713</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000306">
        <property type="protein sequence ID" value="ODM98981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N196"/>
    <dbReference type="OMA" id="NDLVFCC"/>
    <dbReference type="OrthoDB" id="332390at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008623">
        <property type="term" value="C:CHRAC"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045740">
        <property type="term" value="P:positive regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031445">
        <property type="term" value="P:regulation of heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15532">
        <property type="entry name" value="PHD2_CHD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15627">
        <property type="entry name" value="PHD_BAZ1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000300">
        <property type="entry name" value="Bromodomain adjacent to zinc finger domain protein 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047171">
        <property type="entry name" value="BAZ1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018501">
        <property type="entry name" value="DDT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013136">
        <property type="entry name" value="WSTF_Acf1_Cbp146"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46510">
        <property type="entry name" value="BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46510:SF1">
        <property type="entry name" value="BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02791">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10537">
        <property type="entry name" value="WAC_Acf1_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00571">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50827">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51136">
        <property type="entry name" value="WAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WAC" evidence="19">
        <location>
            <begin position="22"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="DDT" evidence="18">
        <location>
            <begin position="407"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="17">
        <location>
            <begin position="1147"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="17">
        <location>
            <begin position="1242"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="16">
        <location>
            <begin position="1493"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="263"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="672"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="808"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="922"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1021"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1203"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1287"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="270"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="331"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1034"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1220"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1295"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1329"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1352"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1406"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1430"/>
            <end position="1439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODM98981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1587" mass="180136" checksum="34897562EA1CDC1E" modified="2016-11-30" version="1">MPFFKRKPFVPNPPPSDLKGDEEVFFLRLTNEIFRDYDEYFAQVIQCNSLIWSCSLTGKSGLTFQEALESERSAKKFLKGFPRPLKKALFYLATLTKRGRFSDVVEDVLTYARERYFKGEEVFSVIGNMWCPSKVISIIAPTPAEMEQYKQDQIEKGLEDKNDYLTDDSWGPAPDLFRYEVQEIDPDNKTPTSSETHVLEAIDVKREKTILTRDKCRILLKLATDMIDEKGLVMVKPIVITDYGLQKAKYDEMFIGKTPIFEESPAPVKPVKDSSKSSKSKTPKEPKKEKSSMEKEKSKSGEKKAKSDGKEKKSTSPANKTAKAGSAKSKAKPEAKSKKPKVEKQLTQQELKQLEMVKKAKEREKLKAQKKLVADFKKLWFKPKEDLEVEDLKDLPIPDPVCCKIPNNLFGEFMMLLEFLHCYSSTLKVRDCFPSGVTFDILERALTKNEVAGPFSDILQLLMKTIFRLQETENAEITEVETATVDFEVNDVGGDVTAREAVQLATAYSTWSMMYQNTPLHKLGVDHLSITEVLRLHLLSSGAKPSEKDVKWRTQQRGGYTETDDPGLQLRLEEPQIIKSLNAGTVFDLTMREKLKLVQCLINQISTYVSVRDAMEESFDQLRLVRANLKSLQVSEKKKDAEDNYWRQKLKADKLMPDMTLFKAVPEKIIAESQDGENDQAGSKNGKGKEKPPEKPSKPPMTDEQIEAALAKKDKEIARRKQDFLWKEDELQEQLHKQERRLGIHPVGKDRAFRRYWTFSTVGGLFVEHDDEYVGDCLPAPTPFIANVDFDNLSFVKETYDKYLQMDKEGSDKENSISNSPKKSKKKASMSSAVKKEVSERPAIFGMCTGDKESCPVHCIYLPRPKWSFFWNPEHIDALIENLSPRGIREKELRSALVEEKDPIKAHVNKCPALKLNREGQFPEHISNAPDKRPQRGGTTQKNRIDPNLSYPAGTNIETILELQLRDLILEVEEKIFLGALGSVKVSDRGVWRKALEDREYDPQASKLSWTGGKSLNVAKRHGRLNGNSAGEGTSKSDQLSSHTSTSSEANKDDSTSLNPVVKDLACAILQIRQSIEPKFLKRPLGEEDGKKKKSKEAELSSKISLPAPTAIERWELSLMACTSFSQLFVHLFTFDNSVEWSRSVLNARCRVCRRKGNPENMLLCDGCNKGHHAYCLKPPLEVIPKGDWFCYDCKPIELPPPKPRSRARRLSDDDDILQELDRNDSDDENGRSNDLSEEVEQEGCAVCSFGGELMCCDGCPDMYHLLCLNPPLSRVPRGIWHCPNCKSQAQKGKSSSRSKNKSKARRTISTDESDEDTLRSDDESEPEASSRSRNHSDDETDRATDDDDESDKTTDDEREVVKVKFTKKPTERTSGNNRKRVYEDDEDYESEDDHHFGRGSRRKCASQAAAKIAQVAKRLRSDSKENESSDNSNDSSSSGFQAGSRSKRSNELEMYDSDAPKRTRLQRMNTNNCVRNGELDNVLLDKILSEVMKQAEAWPFLKPVTRNEAPDYHEIVKHPMDLGTIKYKLNSMVYTCNEEFISDLLLVFSNCEMYNDPSSRIHQAGRTLKSFCERKFSKIGITISDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2G1</accession>
    <name>A0A1D2N2G1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000280">
        <property type="protein sequence ID" value="ODM99462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2G1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904927" evidence="1">
        <location>
            <begin position="27"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="127" mass="14646" checksum="88FC83D829D0F1C8" modified="2016-11-30" version="1">MRKDKLCFSVCVIFAMLLTLTTICHSNFQYPNRIGISDQRRNFRNFSQQHKPFNSSLYSFSLINGLTKQRKSRSGKCHSHEHCQEHRSEKRSITNVSTVTSVNVEGIVRVVDFAFTLADISDYPKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2T5</accession>
    <name>A0A1D2N2T5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000272">
        <property type="protein sequence ID" value="ODM99541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2T5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904945" evidence="1">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="24966" checksum="C4D82EA572DF17F7" modified="2016-11-30" version="1">MVGIYKYLAIFAFATVVVTQVESELRSPNYSVCSDFFVGKCENGLASDAMFFDLQITGVSVIGLHIFMAQGRNGEPTGLAEFVFQENFGQYYQLTETAGLVTSLKRLGALDYKTPAISFAYELELITDGVAKFEDSAGSIERCSVAPATKSLVVHGVESWELVLNNGTSICLQVENTNSFVPGIVKDIENIGLPRDPFANICYVVKGCTLPPQQIIRIPNNVTSGVLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2Y1</accession>
    <name>A0A1D2N2Y1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Nidogen-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_07031</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
            <location evidence="1">Basement membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000265">
        <property type="protein sequence ID" value="ODM99647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2Y1"/>
    <dbReference type="STRING" id="48709.A0A1D2N2Y1"/>
    <dbReference type="OMA" id="PGTGNQF"/>
    <dbReference type="OrthoDB" id="6375837at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042813">
        <property type="term" value="F:Wnt receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017147">
        <property type="term" value="F:Wnt-protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000241">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.155.10">
        <property type="entry name" value="Green fluorescent protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050778">
        <property type="entry name" value="Cueball_EGF_LRP_Nidogen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006605">
        <property type="entry name" value="G2_nidogen/fibulin_G2F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009017">
        <property type="entry name" value="GFP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003886">
        <property type="entry name" value="NIDO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513:SF13">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513">
        <property type="entry name" value="VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07474">
        <property type="entry name" value="G2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00058">
        <property type="entry name" value="Ldl_recept_b"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06119">
        <property type="entry name" value="NIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00682">
        <property type="entry name" value="G2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00539">
        <property type="entry name" value="NIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54511">
        <property type="entry name" value="GFP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51120">
        <property type="entry name" value="LDLRB"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51220">
        <property type="entry name" value="NIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50993">
        <property type="entry name" value="NIDOGEN_G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0084">Basement membrane</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 12" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="NIDO" evidence="16">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Nidogen G2 beta-barrel" evidence="15">
        <location>
            <begin position="195"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="468"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="511"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="556"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="652"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="695"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="739"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="782"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="13">
        <location>
            <begin position="916"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="13">
        <location>
            <begin position="959"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="13">
        <location>
            <begin position="1002"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="13">
        <location>
            <begin position="1047"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="522"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="566"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="663"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="705"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="749"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="792"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM99647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1174" mass="128117" checksum="2537F5B6AC65F345" modified="2016-11-30" version="1">MPLFRSHGLMSGRSTNNITNSSVSDVRCEASEFSSSSKCAPARTNTYQLVIASDGGESYVAMIYDKIDWIQGTGKNPNLPDAKAQAGLIAGNGGPHYSLRGSGTDQVSSLNKRSNINEDGVWAFRIGRIGDQVEQPDLNVNLESSSEASSSCAAGGFTSCHSSANCVDYEPGFCCQCTRGFYGNGRVCLQNGTHVPVRFNGKVKGVLNGMAIDDADLFSYILPQDGRSYTAVAKIPERLGYDLQSVIVLGTSIGWLFSTSARGAPNGFMLTGGLFNYTADINFFQTGQKVQVHQSFLGLDVFSHMRVDTRLHGSLPLVPVGKSIEIVDLKMEFTRVAPGTIRSRSSHTYRVEGTSVDNPFSLVQTIEYNECPWAAPVPPELDTTTMKVGKNYIVYDSTQGIGRYAITSTITPVDGNDPCKENKDKCGPNSSCVVEGDNFRCICNLGYEQHYNYEATDINPDDPPQCVDINECQIGTSTCDVTAVCINYPGSYRCECPPGHSGDGYTCTNNSPPDCRQVRDLCDPFAECIYSRSSDSYICSCQPGYHGDGLVCHREPTESCEIENNCHPEADCRLDESAQEYICVCRSGYQGDGYVCMRSGGHDGHGREEAVPPPICVLGSCYCSTGYEYDDLRGVCVPVTEVVSSAETNNNNEMQCDVLPQMCDINAVCMYNSNIGRYACKCKTGYAGSGRECSPQDFCSSHSECSAYGECAYDSAELRYSCRCREGFTGDGKECRPKSDVGCDILRNCDSNAQCTWDSAQTKYACECQPGYKGDGLMCQEDLESCNVLQNCGENAECGYESESRSYKCQCLPGYEGDGFRCRSAVPCYQDPLVCDANAVCSVDQRSREWTCQCKPGYQGDGHTCKEVIPMSGGDFLVVTKGMSLIKVPLGNGRAVPLVVEPFQTAIGLDIDCPNQQIYWSDVATRTIKMASFNGTDRGTFLDDEIGSPEGLAIDPVSQTIYWTDSLKDTIEVASLKSKLRATIISTGLVNPRGIAVFPQRGRLFWSDWNRDYPKIEYSGLDGRERQILVGEGLALPNSLVVDKNTEELCWADAGTHKIECVGIDGRNRRNYVSKIKYPFGLAIGPESFYWSDWETKKVERASRQSGELSTGYDVHLGGTGKLYGIVYVAATCPNVYSPCDYNSCGEERLCLPNARNGRSCICPDGAVNCQNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N396</accession>
    <name>A0A1D2N396_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BTB/POZ domain-containing protein KCTD3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06924</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KCTD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000257">
        <property type="protein sequence ID" value="ODM99757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N396"/>
    <dbReference type="STRING" id="48709.A0A1D2N396"/>
    <dbReference type="OMA" id="YFMHSAS"/>
    <dbReference type="OrthoDB" id="6077599at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18363">
        <property type="entry name" value="BTB_POZ_KCTD3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000038">
        <property type="entry name" value="BTB/POZ domain-containing protein KCTD3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047876">
        <property type="entry name" value="SHKBP1/KCTD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15859:SF1">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15859">
        <property type="entry name" value="SETA BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BTB" evidence="6">
        <location>
            <begin position="6"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="124"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="734"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="734"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="758" mass="83009" checksum="C1E167E0EA142E69" modified="2016-11-30" version="1">MMFGSDIVHLNVGGTRFSTSWQTLTWVPDSFFTALLSGRISSLKDDSGAFFIDRDPTLFSVILNYLRSRDVDLRHVDMRALRNEAEFYGITPLVKRLALCDDLNYSTCGDVLFHGYLQPASLPMHPDTVLRQPSTSNTSSAPSTTTTTKPEEVPSSSSSGNGSTKSTDLRPTPGSIVRVPETHGAAGSTSTVNRNAHSRSASSGSGATGNGFTWTNTRNGHSRGSSVQHSRNSSFDARHSRNSSADLNKYFRTELSILSQGNWVDPMRVRIVKAHQNWICVAYSHFVTCYRQKDSSGWQLVFTSPRVDNMIDRLAINAKMTLGQGSSSSGNESNAKMVAIAAGSVVFMWGVSDDGHRTDIGQFSLPVPIDFLFFIGTQLVALSQNGKIGVWHSMTQHVLVQDIVSIQSFDTAGSFLLLGCSNGSISYIDMQKFPLRMKDNDLLVTELYKDPSNEPITAISVYLTPKTSLSGNWIEIAYGTQSGMVRVIVQHPETVGHGPQLFQTFTVHRSPVNKVKLTEKYLVSVCSEYNHVRSWTMTRFRGMISTHPGSTPLSSFKIVALEEIESNQSYVAGNDCGPYGDQDDEQVFIQKVVPETDQLYIRLASNGKRICTIRSVDGTTITSFCCHECEGSSRMGSRPRRFIFTGHSNGAIQMWDLTTALDLAQKGEPATQRSGGPTPEELLRLLDQCDLSTSHASTPCPSPNPSLLGGSGITQNRLKASNVAFLSQQSLQQHSAVQESSSTENQMTNDDLCGPHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3B9</accession>
    <name>A0A1D2N3B9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06917</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000256">
        <property type="protein sequence ID" value="ODM99769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3B9"/>
    <dbReference type="OMA" id="CEYAISS"/>
    <dbReference type="OrthoDB" id="10581197at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904973" evidence="3">
        <location>
            <begin position="22"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="316" mass="35408" checksum="259BEB842E1E0062" modified="2016-11-30" version="1">MNFISIALGFIFTLNLELTVCMKNNAYLLQDHKNNALVISITNQNGFKSSSNNSQLFTVQAPKYHRVMIVIQQLHLWSEPDPDFQSYLQFMDSDGSASEIVYGNIDPDETDKIPQYLTGPRSFVSTDDTASLAFINLRPDYIISSKNERRVYAKLAFTAFRDTCSYRSIPPLNSSDLESVTKLKNEVVYRSCITSSASGKNCIAAELFCDSIINCGETESGTFGLDETYINCDAKTSASRTFSTTSQPEDDGQESPKKHDKKSGDLLKTFILDQDYDEYYTELFKSVIIGFLGLCTTCILIAFVVTMFCLKNNGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3E8</accession>
    <name>A0A1D2N3E8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Interference hedgehog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_06871</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc).</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homodimer. Heterotetramer; 2 iHog chains bind 2 hh chains when facilitated by heparin, heparin is required to promote high-affinity interactions between hh and iHog.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the immunoglobulin superfamily. IHOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000254">
        <property type="protein sequence ID" value="ODM99806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3E8"/>
    <dbReference type="STRING" id="48709.A0A1D2N3E8"/>
    <dbReference type="OMA" id="PISVMWR"/>
    <dbReference type="OrthoDB" id="9998697at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF33">
        <property type="entry name" value="BROTHER OF IHOG, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0358">Heparin-binding</keyword>
    <keyword evidence="11" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0654">Proteoglycan</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="591"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="18">
        <location>
            <begin position="58"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="18">
        <location>
            <begin position="171"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="18">
        <location>
            <begin position="260"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="19">
        <location>
            <begin position="359"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="19">
        <location>
            <begin position="463"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="711"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="761"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="774"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODM99806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="790" mass="88629" checksum="812B7CB36B3A73F5" modified="2016-11-30" version="1" fragment="single">VRWKLNGRFLHPANESDIRVSGTLLSVKVSKNRERYMQQVGDYQCVAEFGAEALTSLPAQLTIAQLDPFQPHSNKTLEVVDGNTVAISCDAPYSNPPPVIQFYKDGRPIEPETGNSMLMDSGILHLYNVSSVDAGSYWCAVTNHITTDTYVAEWVTQLVVLPKSMGARKAPEFLVKPKPYYILPQDGNVTLECVAIGNPPPYTTWRKLRAPTMTNYQTNKGTLHLFNVGISQEGEYICEAYNGVGDAITTLSTIVLNSMPNITKEPMSLIVEEGGEAIIDCASEGLPKPRVYWVFNGQNVHDDGNVQITVIKPPVTSVLPPVTDQENHGYASAHHHKNNKFHRVKHNKRRKHKGQDMTPPSKPTINRLSDDSVMIRWDVPPNSGYPIQFFKIQYKEVSRKNSRWMTIDDDIAPHINSYEVRDLRVGHAYRFRIAAVYSNNDNKVGTNSEKFVLQKDATMRRPASSPIITNAVPHNTSSILLRWKVMNAEAGGLEGYFIYYRETTSAGDYSKVSVPGEEMESHYIDHLKTGTSYDIKIQSFNRAGASNFSSIITAKTTGVATTERPDYDNGKHREDEIIIPDDEPLPTHENLYLLMGCLFVGFWIFICLACAICYRCKQKRAEEEAKYPCDVQLDLENKSISNGHVGMNGHIHGLNGYIPTITSQLDEKETSFVERHNNNRPISPSLLNNSTCDLSSFKSSTLDGKSCTEMKTLGVARKTPESNSRNNSLKRQKHAHSNGNGSLRRGQYMSCSSEDLEGDDDKSKDTRIFPKEHYKARKHNRKRNSMADVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3K7</accession>
    <name>A0A1D2N3K7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000251">
        <property type="protein sequence ID" value="ODM99867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3K7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904988" description="Transmembrane protein" evidence="1">
        <location>
            <begin position="38"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="123" mass="13827" checksum="AAEE4376ECF5F468" modified="2016-11-30" version="1">MRPTRNTFMLEGPVQNMANSHGLMILLLLVTFVFTNGESVVRNESSDITNNSQSKCQTPLGPFYYQHPSLNWKQKNEDNTETDESMGKIDGDLSKSKFWSSGFGFSSHYETLPLPPPIPAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4K4</accession>
    <name>A0A1D2N4K4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000225">
        <property type="protein sequence ID" value="ODN00198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4K4"/>
    <dbReference type="STRING" id="48709.A0A1D2N4K4"/>
    <dbReference type="OMA" id="MTYGYMI"/>
    <dbReference type="OrthoDB" id="8251605at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007430">
        <property type="term" value="P:terminal branching, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.50:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00056400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="348" mass="39963" checksum="E1B0B80A03332EE4" modified="2016-11-30" version="1">MKGCMFNIDNGYLEGLCRGFKTGILTQNDYLNLVQCETLEDLKLHLAGTDYGNFLANEPSPLSVSTLDDKLREKLVNEFVHMRNCAVEPTSTFLDFITYSYMIDNIVLLITGALHQRPLQELLPKCHPLGSFEQMEAIHIATTPAELYNAVLVDTPLAPFFQDCISEADLDEMNVELIRNTLYKAYLEAFYEFCNQLGGETADVMCEILAFEADRRALIITINSFDTELSKEDRARLFPKCGKLYPDGLAALARADDYEQVRSVAEYYAEYQQLFATTGNNPEEKTLEDRFFEYEVKLNVNAFLRQFHFGVFYAYLKLKEQECRNIVWIAECIAQRHRAKIDNYIPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N505</accession>
    <name>A0A1D2N505_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000215">
        <property type="protein sequence ID" value="ODN00312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N505"/>
    <dbReference type="OMA" id="PPIMEND"/>
    <dbReference type="OrthoDB" id="6275292at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033557">
        <property type="entry name" value="CIMAP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34914">
        <property type="entry name" value="LYMPHOCYTE EXPANSION MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34914:SF1">
        <property type="entry name" value="LYMPHOCYTE EXPANSION MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="741" mass="83988" checksum="E6DE122F5FFBCF78" modified="2016-11-30" version="1">MADENSPSDAQNLLSEDAAGPSEEEWTEEEEEQVITKPGASAGTDLDSHLDFLRSLITTVDTPTPPPAPPTYDEEEDEEEEEHQHRFTSGYPEETTGEEEDEDEEEEGFYEHEYDDNEIVELFSPLLSPDGNYNHFEQEMRESGESDEVEDDAFDEYDAKVVDEDTIPQTGNAKQTESEIDITLAPTGGADVQSSAERPSPNKNKKDMSKRSFRWFERQLLYPLIPKPNDEGLRRKQLLEKCQMVRKVSKPVVTLLGAPKSFIASQDVAQGSKDSLNETDVVTKSFKDFTNFDWAMKNTQDFLTNAGCTESSSRTYRSSLKAVNDDKDIRLKIYEKQLKRRRNAIGSREQAPEITAALLRHAQRAVWRAVIDNTKPRYPLPRFIFTRHRYLKRVQAQFIGPGSYEHDVFHSQTKARQQKMPSTWATCNPRFPKDPAEAAAKGGAGAVHLLDPWESLDKANYQKKHPGTCVPFESTPQNFRKSTEAGSKIPPNAYNIKSPLEEFIKQKTSLRGPYDCYTPSRAVIPYGHYQTTTDEDKSRLGPGSYEVRSSLVKEMNDPYNFFKAKFGKAERNKMFGFKAAFDKPLWPKDNGIPPVGHYEGDTEIIGKDRRQYKAPFKVLAGLKKRDENRELVAPDYYYFNGTWTVPPKGADLASVFLSKSPQIMPSKLHHVRKERNRAMNRFCDPLGRHKEEHYAYDIPVKNDYVLEDCKYQCSGPKVDPYGIPGHGVVNATGKSGCCGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Q6</accession>
    <name>A0A1D2N6Q6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arylamine N-acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.5" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000180">
        <property type="protein sequence ID" value="ODN00953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Q6"/>
    <dbReference type="OMA" id="SHEACHY"/>
    <dbReference type="OrthoDB" id="10260017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004060">
        <property type="term" value="F:arylamine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2140.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053710">
        <property type="entry name" value="Arylamine_NAT_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786:SF0">
        <property type="entry name" value="ARYLAMINE N-ACETYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="35548" checksum="301B24E2B13EF6E9" modified="2016-11-30" version="1">MFIKHYFNIANPKELFIKDRLNLLKQLVKASVTRMPFQNLTSFGAFLPCDRATPQFKEVLRSGVKGEGGLCGHLNNFMILHLETLGFDVDRLSGCFRRTGVPMSHQLIKVRIPGHVSKEPVTNPMEKREDRTYIVDVGSGIPLHEPICIEKLPYYGRAGGLNFRYERVDENTLQRVNENGDAIMGNKPSSFMSPQDYTIDLAPRKYSEFNGPVHAIYSNPRSVFLHQGIYCFRYLNFTEDDFEMVCVRGKELILITKETRQVQSFSSYEELKPSLYKYFPMINTNDVELTVKHFSIPFEEAIKMPSNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6X3</accession>
    <name>A0A1D2N6X3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000178">
        <property type="protein sequence ID" value="ODN00982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6X3"/>
    <dbReference type="STRING" id="48709.A0A1D2N6X3"/>
    <dbReference type="OMA" id="HNIKSHE"/>
    <dbReference type="OrthoDB" id="5565075at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000054">
        <property type="entry name" value="Complement C1r subcomponent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="149"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="385" mass="42844" checksum="3AE496881FCB0CDF" modified="2016-11-30" version="1">MALVAVNPRHRIPLSLLSIIQSSREQYKWNIKITQMRCANVNYIKDAPSCGKKWGDIEAETLQTTTLPPELENTVYSVGDGYMDISRIAVDTAFYIDYLKQAHQVLSNSSSNTTTCRNRELDIKKEKLQEQRSEIEDLLDFEDNDKARILRGSDATLHQFPWQVSIQDAKGHVCGGAIISNDSIVTASHCFLSISPVPMRNIKVVVGDLNINTTTETEHTFVNISSITFHSHFDPYYLENDIAVIKLKNPLTFRAGVQPVCLPESGNSYSSKQATVSGWGAVSYPQGKLATNLQFVNNTVIENSACKKTLKIDYITQNMMCAVSYPNCSGTCGPLVVENEKTHVTSLIGIVSFGIGGCALFPSWPDVYTRVSEYLDWLSYAVTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N768</accession>
    <name>A0A1D2N768_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000171">
        <property type="protein sequence ID" value="ODN01104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N768"/>
    <dbReference type="STRING" id="48709.A0A1D2N768"/>
    <dbReference type="OrthoDB" id="1728974at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 3" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="15365" checksum="CE4E09954867C218" modified="2016-11-30" version="1" fragment="single">RSLRDLLNCQHKPFGGVTVVVGGDFRQQAPVILHGNRVKTIESTVKSSKLWRGFKEISLTKNMRVNPDEMEFVEWLLRVGSGLDDEDKKTDFLKLPEEILSDNIIRTIFGTDINELHLNELASRASFAPPAYRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8Q1</accession>
    <name>A0A1D2N8Q1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05074</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8Q1"/>
    <dbReference type="STRING" id="48709.A0A1D2N8Q1"/>
    <dbReference type="OMA" id="DICVDVF"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="398" mass="45206" checksum="F45FF10D425B245E" modified="2016-11-30" version="1">MSPGALCSKQGYPFETHYVQTEDGYILEMHRIPHGKYSSARNVSKYPVIVQHGNFQSSTDWLVNSPESESLGFFLASHGYDVWLGNQRGNEFSIRHSRVPVSSSKFWNFSFHEMGMYDLPAMLDYVTKITQKPKAHYIGFSMGTTLFFSGLSKRPEYSDKIGIGIAMGPSTFQKYFFNSWAKVIAPFTWFIQVFQKLAGDMPVLPQFVANLLHKILPIICNPKVDLIGICMSVVQIGFGHDQGKITKNIRFSSKTTNKNCRVEMTFSVLKEILYQITKVSPSSSSMKAFLHELQLMGTNRFCEYDYGSAENMVVYGREHPPDYNLTNIRAPISLIVGRNDFMAHKEDAKTLGSKLPNLVDFHYVPYEHFTHLDFCYASDVSSLVYKHVVALLNAHDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAG4</accession>
    <name>A0A1D2NAG4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000119">
        <property type="protein sequence ID" value="ODN02237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAG4"/>
    <dbReference type="STRING" id="48709.A0A1D2NAG4"/>
    <dbReference type="OMA" id="RHEEIHE"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="29159" checksum="F6B330E138A4B1F7" modified="2016-11-30" version="1">MAKGKLGRKKWTRKVKSADRKLACSWLGCTKAFRFDFDVKRHEKSHLPKDQRPFLCQPCNLRFAQWDQLRKHQKTPKHARGVALAELANQRGNANPEEEIRQAENGPMEVDINNGVHDNGEEEDHDNGEEEDHDEMDTESDNEVADDEEETEQEESDTEEQEGSDTEEQEGSDTEEQEGSDTEKKEESDTTKEGESASSDKEELGSPEEMELNPPKDKELNLPENEEEAAPDEAEVNSDEDELLDVGWEIFYKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAP2</accession>
    <name>A0A1D2NAP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkylated DNA repair protein alkB 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04364</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000116">
        <property type="protein sequence ID" value="ODN02324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAP2"/>
    <dbReference type="STRING" id="48709.A0A1D2NAP2"/>
    <dbReference type="OMA" id="EYEKYIM"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="231"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN02324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="613" mass="69610" checksum="47406DE9A62E6680" modified="2016-11-30" version="1">MSSSSSIGEDGSKNVEKKAVPRSLGKAERKNARKVSKMKQVVSKQVGVQMSDEPCSEWLIVWGFGASTGTTKNDILDYLKPRPVAVRLFVDQAYVFVRCSSLEDAALLKSKYHGREYDERQTLYVGFVEKYEVIPEEDIRYLAPFNVGLPEGLSLYPEFVTPEEEDCLIKNLFVDTSAVSSLRKRTVQHFGYEFRYGTNDVDPRSPLPNKIPDYVLPTVSKMISTGAAPAEPDQLTVNQYMPGQGIPPHCDTHSCFEGPIISLSLGSDTVMDFRQANSVSSVILPARSLLVMDGASRYGWTHGITPRKWDVVPDKHNGGITMLGRALRISLTFRRLKRGKVGCHCDFPNLCDTQKGKITDDNASVLENDLVHKVYENIAAHFTETRHKPWPKVREFVENLKPGDRMLDVGCANGKYFRINNDILEVGMDMSTGLLEKCLEKGNEVVRANALSLPFKDDHFESVISIAVLHHIATKERRQRFIEEIMRVLTPGGLGLIYVWAKDQNLEKTQSTWSERQQERNFYNPPGSCVDQVSDYLFLPIHDRDEEFPQNDMLVPWVNHQEKQNTVHHRYYHVFNKGELEELITDLEPAPKILDSYYEQGNWVVKFQKQGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBG9</accession>
    <name>A0A1D2NBG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Galanin receptor type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04087</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000104">
        <property type="protein sequence ID" value="ODN02604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBG9"/>
    <dbReference type="STRING" id="48709.A0A1D2NBG9"/>
    <dbReference type="OMA" id="MIFCSDH"/>
    <dbReference type="OrthoDB" id="5953793at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004983">
        <property type="term" value="F:neuropeptide Y receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000611">
        <property type="entry name" value="NPY_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243:SF208">
        <property type="entry name" value="PYROKININ-1 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01012">
        <property type="entry name" value="NRPEPTIDEYR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="113"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="47642" checksum="47F246CCC7143610" modified="2016-11-30" version="1">MRGRGKEVTHIEIVKTNGMSLLSHSVLDVSEGVSGASLFSKMESTSSPLITDYLGGENFSTEIPFFYGVGDEMEDGKIFFSTPEDMLNPSMRNPAFYPIVITHAITFVLGIFGNVVAVSVMIGDRKGRNATNLFLVSLAVADLLLLLLCIPLEVLQYFLQFEDNGVICKVARYTELLSASASVLNLCAVSLERFIVIVFPMRSRSVCTLSNCRKAICVVWVLAVVLSLPVMLTKEGYSVTYTNNITSVSVFYCKEVDENEGLPIAIYKFAILFAAPALLMMICYVYVIKMLILIIILFLVCWGPKLILTITLKLAFIFGLPIYSQEVYVCRVAFSLIPFVHSCINPIVYSFMSKNFRRSMNRQLGRCCVVCGCKCNCNNCGNHRNSIPLRSTARARTTQAVESTYSSNYCQLSDVHSTRHTEIEGISTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC23</accession>
    <name>A0A1D2NC23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">F-box only protein 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03888</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC23"/>
    <dbReference type="STRING" id="48709.A0A1D2NC23"/>
    <dbReference type="OrthoDB" id="9991467at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040394">
        <property type="entry name" value="FBX25/32"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13123">
        <property type="entry name" value="LD30288P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13123:SF7">
        <property type="entry name" value="LD30288P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="91"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="29414" checksum="E90AACBCE6CF65E2" modified="2016-11-30" version="1">MIQLLLFNMNYLPGNVQRILVRLIEEMATYSKENGWKGEMKSVLELMRENIVNQPVWGGQLGSSKLWEEHRNNIQKILNTTSDEDFDSDKGPPILHFPEEVIRQILLKLSSDKDIETLSNTHFLFNDIAHENRVWRQLCNYHFTAAQKDQLLDQQHQNLPPGVVNDNAANHNNNCNDSVSTQLSFENDNPQWKLVYKKLKRKHGLNKEEYAEELNLCKTCGLLFWATSSSNPHDCGMAILIRVKPGDFIKYFCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCT4</accession>
    <name>A0A1D2NCT4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">E3 ubiquitin-protein ligase MARCHF6</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Membrane-associated RING finger protein 6</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Membrane-associated RING-CH protein VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_03635</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with DIO2. Interacts with SQLE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000088">
        <property type="protein sequence ID" value="ODN03068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCT4"/>
    <dbReference type="STRING" id="48709.A0A1D2NCT4"/>
    <dbReference type="OMA" id="WLHYSLV"/>
    <dbReference type="OrthoDB" id="1108038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16702">
        <property type="entry name" value="RING_CH-C4HC3_MARCH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000096">
        <property type="entry name" value="E3 ubiquitin-protein ligase MARCH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056521">
        <property type="entry name" value="MARCHF6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCHF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145">
        <property type="entry name" value="SSM4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23113">
        <property type="entry name" value="MARCHF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="15 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="619"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="660"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="720"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="760"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="806"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="844"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="22">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="175"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="589"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00064724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00069012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00082010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00083917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODN03068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="945" mass="106565" checksum="F5273E586AD419B9" modified="2016-11-30" version="1">MMDDGQQDICRVCRSEGSPDRPLFYPCVCTGSIKYIHQDCLVQWLRYSRKEYCELCNHRFSFTPIYAPDMPKRLPIKDIISGLVTSVATAVRFWLHYTLVAFAWLGVVPLSACRIHRSLFTGSVNSILALPLDLLSTENLLSDIFHGCIVVMCTLCVFISLVWLREHMMHGGAPEWLEAPQEDNPIEIGDGDEGEDNGMNDMDNGNGDGEGDNGLQLDVQAPANQNDNNNNNNVQNARGGGNDEINWNPIEWDRAAEELTWERLLGLDGSLVFLEHVFWVVSLNTLFILVFEFSPYHIGHFTLAGLQLQEMTKVQHFEGLLVTLCGYCVVGICLVLLHAVASIMRLNRSKKVLGLCYVVVKVCLLSVVEIGIFPLVCGWWLDVCSLSLFDATFKDREATFNKAPGTSMFLHWLFGMIYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPIQEMIHLPILRHIRRFLFSMIIFGTTVLLMVWLPIRLIKRTIPTFLPYNFNLLPIFREQAHELSLELVVLQVMMPALLEQGHTREWLKIVVRFWCIVMAWILDLRSYLLGDVPLENNVNGDVVNEHREAAADVLLQRENNQNENVNENEDRGEGGGGGGGGAGGEVGAAGGLGFVIGGGLGAAHQALLLRDGPTGFLPYTRPKLFPAKITLLLLSMCATLTIVSIFILTVPVSVGRFVMRYWLSNPDEPIHELYTTASGLYVTWLTVRLLILFGTWIPRGWAAVWDMIRRWSVTMKTMYQWTMGLSFQVIKTAVAIGLLIGFIPYMCGLLFELLLISPLRVPLTQSPIYLASENWVMGTLYVKIACAGAMMTPQNFWLRRTLERIYNDGFRNINLNFIITELAAPCIVLLGLALAVPYVISQSLVPLFVTNMDSLNVVHRRIYPTFLVTAVVFGVISFQIRQFKKLYEHIKNDKYLGPEEHERPPPSPPVAAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCV3</accession>
    <name>A0A1D2NCV3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger RNA-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03596</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000087">
        <property type="protein sequence ID" value="ODN03088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCV3"/>
    <dbReference type="STRING" id="48709.A0A1D2NCV3"/>
    <dbReference type="OMA" id="TRPWCGV"/>
    <dbReference type="OrthoDB" id="8898434at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002080">
        <property type="entry name" value="Zinc finger RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000153">
        <property type="entry name" value="Zinc finger RNA-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000210">
        <property type="entry name" value="Zinc finger RNA-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000010">
        <property type="entry name" value="Zinc finger RNA-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006561">
        <property type="entry name" value="DZF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049402">
        <property type="entry name" value="DZF_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049401">
        <property type="entry name" value="DZF_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45762">
        <property type="entry name" value="ZINC FINGER RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45762:SF3">
        <property type="entry name" value="ZINC-FINGER PROTEIN AT 72D, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20965">
        <property type="entry name" value="DZF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07528">
        <property type="entry name" value="DZF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00572">
        <property type="entry name" value="DZF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51703">
        <property type="entry name" value="DZF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DZF" evidence="10">
        <location>
            <begin position="522"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="286"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="350"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="479"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="916"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="916"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="930"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="941"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="966" mass="104535" checksum="E49E82BCDFCFE975" modified="2016-11-30" version="1">MAANNYYGFTHAGTQYGNQYTPSQQGYTTAQPYPPPAQAPAVSQGAQAYAPPAENYVISGYTRPAQQSAGAQQSYYPQQSQQTAYTGQTMTSAAASGKVQPQGAVKIVGASSVYPTYNANTAGPGTTSYAGFTQPQQTSTTKAATFTNYDAAVYNAVTAYAQGGTNSKPNSFGFKRQGGGGGPHMNKMKGVRPMQNKPQTLHYCDVCKISCAGPQTYKEHLEGQKHKKKEAAQKAGGSGGVVPVAKGTSGGLRCELCDVTCTGSDAYAAHIRGAKHQKVLKLHTKLGKPIPSDNPTVIQSANANGQGQNQHSSGATVPLKATQKQNTNTSFVKPSASAVKVNFIGPKADYDRYGQGAQQPNESGQQQSTQATSHVQQQPQSVSQTNSGNPTSTNVDMKSETVTTPPSAVGYAEKDIQPVGQDYIEEVRSDDGKVVSFNCKLCECRFNDPNAKEMHMKGRRHRLQYKKKVNPDLVVDVKPSSRQKKMEERRASRVTPARKNQAIGDMFPRGPMPLMPPGGGPRGFAPPVYGAPPGGPHMPFIPPLIRRPESMEDRHVMARHADIYPKEEELHAIQKIVSNTEKALKFVSDEFAENDAMKLNGVKDSAIESKSDADLLQASRVLKGVMRVGHLAKGLLLRGDRIVQLVVLCSEKPTLSMLDRIVDGLPKHLQNVAPDEKYEVIKKLGDAALVVSSSKEPKIEVNVTLTSPLMRTPTPATTGSETGAAAGGKRILKVLLLRREEKFMTSTAVDVGRLVHEAQATQVKDPADVLDKEKCLDALAELRHAKWFQARATALQSCVIVIRILRDLCQRVSAWQSLPCWAVELLTEKSINSSGIPLSPGEALRIVLEVVSAGIFLQNGPGLLDPCEKESVDALKGLTNQCREDVTAYAQQALRQVAFRQIHKVLGMEPLPRFQKKNLMNRKRRRDNSEVGEGDEAEATNDGKKDKKEDVTSMETDVVVKTEPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND64</accession>
    <name>A0A1D2ND64_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Extracellular exo-alpha-(1-&gt;5)-L-arabinofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03665</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND64"/>
    <dbReference type="STRING" id="48709.A0A1D2ND64"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="6">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="355" mass="40433" checksum="DAD2D8B7B65D9C9E" modified="2016-11-30" version="1">MGSQLFQMVLIGVISVIAFCPFSYTASLESSASKGVYYNPIFDGSSPDPYIYLHTDGFYYFVLRIGDGITVMKNDRLTNWRSPLETMEVYQTPNGSANLWAPEIHFFDGYFHIYFTMGTGPIPTQRMWVIKALERDTPFTNYTEKIRLLPPTEDFYQIDGTVVQNGDGRWYMMWSGCDRVGIDNPTNLYIAPMSGPTELSGPRVLLRTRTMDWEGTVLEAPQYLWNEDRLIIIFSANAYQNKNYCLGMMYLDNYSTSDPLNATQWTQNIDHPVFASNDEAGVYGPGHCSLTFSKDYNETWLAYHAMEIPERIEGQPDNRTSRVEKLAWGNDRLPIFPIPTGLGIGLETPTGEPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDY5</accession>
    <name>A0A1D2NDY5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aminopeptidase</fullName>
            <ecNumber evidence="12">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_03496</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDY5"/>
    <dbReference type="STRING" id="48709.A0A1D2NDY5"/>
    <dbReference type="OMA" id="EHWVLER"/>
    <dbReference type="OrthoDB" id="5868348at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000006">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000013">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12 17" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="7 10 12" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905415" description="Aminopeptidase" evidence="13">
        <location>
            <begin position="27"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="16">
        <location>
            <begin position="101"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="14">
        <location>
            <begin position="314"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="15">
        <location>
            <begin position="624"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN03176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="962" mass="107082" checksum="D2F8DDD837ADE168" modified="2016-11-30" version="1">MGHFKTLIFASVLLAVLSNQKTFVQGQGALQIEPSDGLSQLRRNKDAVSVVDTSSKVVPTKKHVGPMDDQTLAWRLPREVLPTVYRVGIAPVIDAGQPVAEQWYVPGLVEISVTAQRATNNIVMHSKNITIHSINVNQGASVIPMTGFVVGGAHDFLNISLGASLQQGQTYTILINFTSYITEDLNGLYRSSYVNPDTGDTVWLATTQFEALHARQMMPCFDEPALKSVFHFQIARMEKYISLFNTESTGVNTTGPAPGWVWETYAPTVEMSTYLLALIISEFTYAEAAADLFPGHRVRTYAPDHYIRDEGGVYAAANAAKILDYFSKYFENEYPLSKMDSAAVPDFYFGAMENYGLNIYRESALLVFPNWTLESERWSISSVLAHELAHQWFGDLVSPAWWTHIWLNEGFATYFAAVGSAHTNPEFESQKRFLNDAVQRSMEVAANPAVAHSVKIDEEEWITKWAMDWFDRMAYEQAGSLIRMMDGFLTTPVLTGGLKTYLNRLQYKAAQQDDLFRDLNIMAVATNRIPENLTMKDIMDTWTLKAGFPLVRVSRASSNRVYVSQEKFTLNAGAVSVPTDQENDLWHIPISIATQSSPNFEPTAEQWLDKNVAMTSWEMNAEEWIILNAGATGYYRVLYDLPLTNFIKAQLETDHTVIDPLTRSQLLDDYFTTAYQQYQSLGTALGLTNYLAKEDEIVVWNAVLKHLRTPLNLFQSTGSYANLRNYLLPKLKGAINLTGGVEAEFGERAGMPILRHQQFMDWACAMEDEECQDFAVRRVSQWMSSSDNSIPRDFHQITYCAAVAKGEDSVFQFILDRYQDTATTRIQQGYLLSALACAANQGSIGRLLEGSLNAGFFRSNGDGSATLQRLATRPVGRAAVLRFVRENATDIATHFGSAAPIASVFSSAASYSSTTADLQNLETIATEIAATVEPVKATIDAAINTVRQNIVWMSTFAGSFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDZ5</accession>
    <name>A0A1D2NDZ5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic peptide chain release factor subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03497</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer of two subunits, one of which binds GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDZ5"/>
    <dbReference type="STRING" id="48709.A0A1D2NDZ5"/>
    <dbReference type="OMA" id="RCNGSEE"/>
    <dbReference type="OrthoDB" id="10254527at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000009">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000001">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.960.10:FF:000001">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="entry name" value="eRF1 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03676">
        <property type="entry name" value="aRF1_eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="444" mass="49643" checksum="6395DBF7F07C99FD" modified="2016-11-30" version="1">MSTNGTYGGGSEDSAARPNVEMWKIKKLIKSLEQARGNGTSMISLIIPPKDQISRVSKMLADELGTASNIKSRVNRLSVLGAITSVQQKLKLYTKVSPNGLVIYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVATTLFISNDKPNICGLILAGSADFKTELSQSDMFDPRLQAKIIKLVDVSYGGENGFNQAIELAAESLQNVKFIQEKKLIGRYFDEISQDTGRYCFGVEDTLKALELGAVETLICWENLDIQRYVLKNHGNAEEKILHLTPDQEKDKTHFTDKESGVELELVDCTPFLEWIANNYKTFGATLEIITDKSQEGSQFVRGFGGIGGLLRYKVDFQSLQLDDFEEDFDIDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE50</accession>
    <name>A0A1D2NE50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fructose-2,6-bisphosphatase TIGAR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000070">
        <property type="protein sequence ID" value="ODN03548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE50"/>
    <dbReference type="STRING" id="48709.A0A1D2NE50"/>
    <dbReference type="OMA" id="ISYGDWD"/>
    <dbReference type="OrthoDB" id="8275317at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="232" mass="25998" checksum="6856BC314A3233EE" modified="2016-11-30" version="1">MFTVTFVRHGETKMNAAKIVQSRTPGELSERGVHMAESLGKHICNEKFTRIYSSDLTRCHDTTLHILKQSLQGQPDLVLDETLRERDYGDLEFQSTSVTHDIHVETGNPIHAIPIPGGETYEATMKRTAKFFSGLCKLADASREPENVLVVTHGAWLMCFLDYLATNKGAFELENCDETQRTSAPRNTATTRLIIHKKGADGNEEEKRRVEFIQIHDIAHLVAANIIPISPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEN5</accession>
    <name>A0A1D2NEN5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Elongin-C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Elongin 15 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">RNA polymerase II transcription factor SIII subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">SIII p15</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Transcription elongation factor B polypeptide 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_03115</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Heterotrimer of an A (ELOA, ELOA2 or ELOA3P), ELOB and ELOC subunit. The elongin BC complex interacts with EPOP; leading to recruit the elongin BC complex to Polycomb group (PcG) target genes, thereby restricting excessive activity of the PRC2/EED-EZH2 complex. Component of multiple cullin-RING E3 ubiquitin-protein ligase complexes composed of Elongin BC (ELOB and ELOC), a cullin (CUL2 or CUL5), a catalytic subunit (RBX1 or RNF7/RBX2), as well as a substrate adapter protein that can be either ASB2, ASB9, ASB11, KLHDC2, KLHDC3, KLHDC10, APPBP2, FEM1A, FEM1B, FEM1C, LRR1, PCMTD1, SOCS1, SOCS2, SOCS5, SPSB1, SPSB3, ELOA, VHL, WSB1, ZYG11B or RAB40C. Interacts with TMF1. As part of the Elongin BC E3 ubiquitin ligase complex; interacts with NRBP1. May form oligomers as a KLHDC2/KLHDC3-ELOB-ELOC complex; this interaction is autoinhibitory for the E3 ligase complex as the substrate-binding site of KLHDC2/KLHDC3 is blocked in the oligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000069">
        <property type="protein sequence ID" value="ODN03565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEN5"/>
    <dbReference type="STRING" id="48709.A0A1D2NEN5"/>
    <dbReference type="OMA" id="DCLENEM"/>
    <dbReference type="OrthoDB" id="249087at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140535">
        <property type="term" value="C:intracellular protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18321">
        <property type="entry name" value="BTB_POZ_EloC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000016">
        <property type="entry name" value="Transcription elongation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="17">
        <location>
            <begin position="84"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00075906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00076689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00080440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00083625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00093535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN03565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="19558" checksum="C3772DDF02B1E25D" modified="2016-11-30" version="1">MSSTMPTSENMDVDKVEVEKEGSDTLIKMGKSKKKKKGVDYAALAEAQLDAAASKRMTMAAAEEAEVDDLSKKYGGCEGPDAMYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENETNEVNFREIPSHVLQKVCMFFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFM7</accession>
    <name>A0A1D2NFM7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFM7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="485" mass="56410" checksum="4F56BD99A4F2929B" modified="2016-11-30" version="1">MNPRVYPTTTRRIIAVDGGFVTRYNRGNQRGGIHKLRDDRFSQPRGRGRGRGMKRPFTFRHEVEHPRFRQYNKEWSPTRPRAVHHLNEERQARAPSYDRPKKKPFRRSRSRSPQNPRVSAHARDGGFVTRFNGGSQRGGIRKLRDDRFSQPRGRGRGKVMSRRPFTFRHDGELPRFRQDNNKEWHPTRHRTVHRLEDERKSRTPSYDRPKKRPFRRSRSRSSPQSLRVSPDARDVSRGSSCRRSVECADADSTETTTKFSDSPGSVTLYNPAEPTCDDKYVGGLIIGPLTPSLPVTPPSHCEGEVLNSENHKVSVPSHEAIQTVVGYQMKYDCTMARQRYELYFSREVPQRKIFKRIKINLSQEQVYSRYPNFVNNTGMSEVVDLLEIDDQELEGIVIPEVVARTRMIVRRQKLHQMCVSRFGEERMIKLMVHLDIKRKTADIDLIELYEEMLSKYGRTSSTNPTHNPFTTQRTQNGAPNSNNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFX4</accession>
    <name>A0A1D2NFX4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein Skeletor, isoforms B/C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000054">
        <property type="protein sequence ID" value="ODN04127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFX4"/>
    <dbReference type="OrthoDB" id="2448405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019545">
        <property type="entry name" value="DM13_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052126">
        <property type="entry name" value="Spindle_Org/Thrombomodulin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24036:SF13">
        <property type="entry name" value="PROTEIN SKELETOR, ISOFORMS D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24036">
        <property type="entry name" value="SKELETOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10517">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00686">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51549">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DM13" evidence="2">
        <location>
            <begin position="40"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="DM13" evidence="2">
        <location>
            <begin position="156"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="445" mass="48012" checksum="47161CBCBFC9E294" modified="2016-11-30" version="1">MVNHASHLNTILNDNISCSFFLKFTADSLLLQNVGSAYRGKYLGPLTSRKHSVTGHVYAVDSRTLHLQGFTYDGTGPDAFFWIGFTESPSPQGIIVPNERGTKEVLTAYNGNDITISLPDGLTLRDIKWFAVWCRAYEVNFGDLYIPPNFDYPQPHVIGSIVGQGVSSGPIVVVDAQTILVPDFTYDGQAPDLHFWVGRGAPGPDGIRVPDETGGDAALARADKKTLVLSLPGDLTIFDIDYFGLWSRLYGIDYGHVRIQPSLNVPPSLRMLGISPQLLSVTPSPYLQTTTAAAAYPQQLAYVHHDTNALVHPAPTYVQTTATTAVAPIAQQLPQQQYYHFVETQKPVVHQPTHAVHYNTALGSAIAAPQGNLITYHQASTPSFAAAPVHTNHITQDGLFYSHAPLTAAATTTALSGGYHTIGANGFSTYTLRTSHGAATAAALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG05</accession>
    <name>A0A1D2NG05_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="9">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_02470</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000051">
        <property type="protein sequence ID" value="ODN04200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG05"/>
    <dbReference type="STRING" id="48709.A0A1D2NG05"/>
    <dbReference type="OMA" id="VDEYCAW"/>
    <dbReference type="OrthoDB" id="65596at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17059">
        <property type="entry name" value="Ubl_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048857">
        <property type="entry name" value="OTU1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057766">
        <property type="entry name" value="Znf-C2H2_OTU1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21403">
        <property type="entry name" value="OTU1_UBXL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24560">
        <property type="entry name" value="zf-C2H2_OTU1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="10">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="11">
        <location>
            <begin position="160"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN04200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="39423" checksum="6EB0344022208526" modified="2016-11-30" version="1">MASGQKLALRVKSKKSQNAILRDVNTQETVQSLLGKLSELTGVPEGNIALLKGFPPKRISYETSNLVESLGLQNQDTIIVECDTNGTPSRGGEGAVVGIAGGSSTKSTSDNDKGIIPSPEVEELSEFATVEVIDPPPIARNSPPFVDLVPSVGDDDSGLLLRQIVPSDNSCLFTSVTFCLSGGPSVQLSGDSSFLREMIANTVAADPGKFNEAILGRPNADYVKWIKKSESWGGGIELAILSEFYGMQISVVDTQSVHISNFGEDQNFAQRIFLIYDGIHYDPLYYEPFNGGSTRTIFEVSNKKMNDLAMQLAREAHASNQFTDLKNFSLRCQICNTLLKGQEEAQAHAKKTAHTAFAEIIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH93</accession>
    <name>A0A1D2NH93_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein unc-79</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000047">
        <property type="protein sequence ID" value="ODN04336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NH93"/>
    <dbReference type="OMA" id="GKERRWM"/>
    <dbReference type="OrthoDB" id="6270916at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024855">
        <property type="entry name" value="UNC79"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21696">
        <property type="entry name" value="PROTEIN UNC-79 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21696:SF2">
        <property type="entry name" value="PROTEIN UNC-79 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14776">
        <property type="entry name" value="UNC-79"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1437"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1608"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1677"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1741"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1615"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1745"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1786"/>
            <end position="1803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2523" mass="281023" checksum="28F7B35EE01CCA5D" modified="2016-11-30" version="1">MLPRFCHCYQEPVLVGVFTKIIIPKTQWEREPRHSSHYSEILMFSVTAKIRNLQDYHLRLTNGIVPLPTGLDIANTLKHFSQTLLGTFGFKKLILYQDCSYPVLKDVPQYPLEMLKQRTEETVRMQLFPNLDYNALFNVVVQLIDVAPMVQLGVQGQNDTLGQAILQTIACLLPFLEHEHIDTLPYIVATSLGTFPSSLHKDIIDLLCHYLLPFTLYLMAFYNDNVLFLLDNCDQCPDKAAYAMQSVSAVLMMVFQYTSSSEYHCQILESVMCYKRDAIKDLLCVIAYGTVEARKVGMNLLVYYWPHVNPTLYDRRNVNFNFNGYKIPGCRSEMCSVNNTGMCADAAKVCFDHSVGISLAPENPPPLFLCQECSSRLQSEQPTASEHLYDVSLPIIKAGTTCENKNCRSQGPDKVLNAVICFHSECASYNGNRPIRYCSQCHSIRHNNRRGLDHVFHKSIQTPDTSDTELLNYHVEAVVSALLEAEPLATRGGTKDVLDQQTRLRLFTDGEFTDPIPIEERRLLGRFGIWLLVGFFNPEDDMLKDVLSRLLSALFQWFNTTAYLGNDPSANALERLKVDFVCPWLKRVVKGNFETFVTCLLPHPPDYARVGGHWYGLIIAKKQKLSLSHITPPICLLLLISSRTFHLREGFNRLFCLVPYEVISPEIWSQIMPHWMEAMASEVPEEEMGELKIILRYNILEYFLHLPNTLQTKTKVMDPEMNPLGFEARQMYQFIAVRFHQTSHKVKEQALKWLQVLSKLEIVIPLYFIFSIFREGIRPKTDKVPKRGSVSQSADTKDVISAICPEDSPQASIDLSDDEENIQLHTEQQSDSELMLSSFIFMLDIILKQLELQEVEQHKGLHTLVAKDAMVLLHNMVAMPWPGTHTCQQSQDCQFCEMAVLWYQLALEIVQKLAPENSALAPDVILSPDGEFGGKGFLEGAAKQELKDSKAAVSPKSESRGLEGIIVNMPQVCIMSSQILTATVETISDFDMGPIMPPTHTATAASIERPTSLNKSAVARQVTITDTETASATAQISSTPLLLENTADVNDKRENWSTTLGDFQFSIEELPPFLKFTYELLKAKDPEVMHNMLKCLRIMFLHGEVFMKASKENRGFVIWCQENLILKKNIEGNLDNFIRKLGRIHEALMKHENNYAAGSKTLYASLGSKMTYKRTMSAPGGLHAKGNDKGYWRQSSAPTLKRKGSRHGVEGYIHGLLGGDDSHLLGIFHRIIEIEEADKETMHLLTFLFMQFLSRYNRGPIPSENSKALARTQNVLLRHLNMLLGHNPQDKTFFIPPSRMRSSPVFNSFISALPQVLDQNFRVGGTLLPMSLTILQYCPAPSKNAGSRYPSYSLWYLEPHVRRSWLMSLIVVLYKYEYGQSPLSTQVQSVIRIILNTLNYQEHKCRPLPSTLILDEPIGRSRADISRVNIGNAAGDLEHITEHETPPITPLSTHNVSPSFSSTREARKSVSSISSVKQQKKGTSGGVSESFDMMSSTDEPDDIEPELAAIPESPRLISSSDVVYIYNSTALISYSSNCAFKELVEQPRITAVVHSADEFQTIDQLQSILPVVISESPKIVHSNSGSAPLSASSEKSKSIGWFIGSSGTASEGDNKSSSSGGSTSSKSGVTVAKSAGGEFPWHLSVQAALQIAKIPAPPLERLLPVGFNAPPLSPTVKSVPRISNNGGHGSPYESPESPMSRMDGMITIGPTFRIDEGEINEALQPERQHAHVDRLLSLGAQGSDKPYKHEEHGKGLHKAEGAGNVSPKKLVKQPRVCDSDVFDGTQQRDEGMEKRGAGDHDAGKSVGFAYERFSLETRSNVESSGQPSRYVLQNLRQSCLRVGEECVQERCGDCGVLLESYTNDELGLCIVALETFIHREPSVAAPFMPEILKVVTSFPNCKYIVGFRIALKPLFPWQVEGSSYFPGAVSSVAHQFLRCVLHQLAPYGVFVQLFQTKFPEKVKVDLFKSISLSLADFAALNPVAPLQMLFETLNARKSIVMDTVAPIIENLATYMECLPLEAASATWSAVIPLSEAFLRKIMPLMQNLTGVDGILRTMACLMRLPGISAFKSILDPFSKILGFVLGNLGLKYNTLVELCHLCHRGFLREREKLLLTRIAILELVQALKFKSNIPDSNFLTLVTFALQDAGGSLAPFVGTDDFPKFPTCEPSNAPTTGAAECMRQHLTDSLEFLADFHSLSKIKSNYKGNGCGLNEDTLGGVIKGGISQFIALEISRGNSRENRAIGRHLPWLYNPPSAIQQGPKEFLDCVAHIRVLSWLLLGALTHTAMFGPTSNVACVPIPLEASCHVADHVHVIMTGFAEQSKASVLHMSSLFHAFILCQVWTVYLEQVGPAAQTSNSSDPANVSTNILTDFWGKVTPAILQLISHSKVLAEMVNLHFLSLLESLLECNSSVFSRLLPLWNPVLFAHHGQLPAHVQVRLQTCLGYPPPDFLLQEAPSATAATTGMNPGHHHQHHHHDILEFPSPTCGPIHNLLLLKWVQRLQFKMGQIELQSSAATQFYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHG9</accession>
    <name>A0A1D2NHG9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron hydrogenase large subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000038">
        <property type="protein sequence ID" value="ODN04662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHG9"/>
    <dbReference type="STRING" id="48709.A0A1D2NHG9"/>
    <dbReference type="OMA" id="GYLHHVL"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase large subunit C-terminal" evidence="3">
        <location>
            <begin position="113"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="473" mass="52395" checksum="BFBB17F3B70845C9" modified="2016-11-30" version="1">MSTGGFSSILKIADLDDFITPSQECIKPVERPKITQPSVSGSKIRIEIEDDGTYSQIKEGIREPLQKVQVTLADCLACSGCITSAESVLISQQSPDELFRILELNKTTNDTKAIVSLGVQAVLSVANKYNISCQEGGERLAGMFAELGADYTTVVTVAEDLSLIESYNEFREAFKNGNVPILAGVCPGWICYSEKLHQHALPKISKVKSPQQIMGSLVKLIYGKKNDISPDQIYHISLMSCFDRKLEASRTDFFIEEYKAKEVDVVITPIEIEQIFSTMNKSLEDFERVPLMDLFSKGDIGTPIPNYQIMSHIGSGSGGYAEFIMRRIAKSLGQELGDIEWKVGRNPDITEAALTGSDGKPIKFSIATGFRNIQTLVRKLKAKTTMPHYVEIMACPTGCLNGGAQVRPANVEATQSRELSAKLEQEYRNLPPVQDTLAAETIYETIQNDPKLFSHVLYTEFHPVEKTNLGMKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJC6</accession>
    <name>A0A1D2NJC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin cytoskeleton-regulatory complex protein PAN1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJC6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905645" evidence="2">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="25917" checksum="F042FB90604CD15B" modified="2016-11-30" version="1">MQPFLAVATLVAAFTVVNSETAYILQPIHHGGHHHESIVQPIHEPIHHQSVVSAVHQPRVLTSGWGWRPTKTITLALPSISRGWGWRPKLPSLQLGVYGGIRIGQKQQGWGKQQQGWGWQPQKQQGWGWQPPKQQGWGWQPQQHVHHETGWGWKKQQHGWGWDDDDDEDDYRALTIDQTALADISDDASSEEVADDDASSSVESEEQDSVEADSPLDYRRSIVYDPYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJC7</accession>
    <name>A0A1D2NJC7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amphiphysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01467</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000028">
        <property type="protein sequence ID" value="ODN05215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJC7"/>
    <dbReference type="STRING" id="48709.A0A1D2NJC7"/>
    <dbReference type="OMA" id="KIGKTFQ"/>
    <dbReference type="OrthoDB" id="446293at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003005">
        <property type="entry name" value="Amphiphysin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46514">
        <property type="entry name" value="AMPHIPHYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46514:SF3">
        <property type="entry name" value="AMPHIPHYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="3">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="69" mass="7944" checksum="C9D49957F17D2C07" modified="2016-11-30" version="1" fragment="single">MSTMVDSKIGKTFQRSVGRAKEKILQNLGKVDRTADEILDDHITNFSKQQYAATRLQKELNNYIRCIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJD9</accession>
    <name>A0A1D2NJD9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000024">
        <property type="protein sequence ID" value="ODN05374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJD9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905650" evidence="2">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17178" checksum="8EA3AF00B131B689" modified="2016-11-30" version="1">MNVNFNIVVCVVAVFLTSNTHARQGGVACPQEGEQVCITCTCDSSNRGFNTCEPTDSCPEPLQSTSGITKKNKASSCPFGAQFTAQCALCECSGTKTGDHCAMCFALPVRRLGQPEQVNKELPQNTDNRFFNYEINGWDAPVEEEEDDEPAADEPDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJR0</accession>
    <name>A0A1D2NJR0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclin-L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJR0"/>
    <dbReference type="STRING" id="48709.A0A1D2NJR0"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000031">
        <property type="entry name" value="cyclin-L1-1-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="177"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="5">
        <location>
            <begin position="288"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="292"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="42"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="401"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="409"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN05484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="560" mass="61282" checksum="99F1C12DBB2F4A47" modified="2016-11-30" version="1">MSVTSFSSGNVSLRPVGDGLVGGASYTNNSTNSLKKSHLLTTTSGGLSSSVMTSNDSLRKSGSSVDIRKNNTSNSTTTSPTRGVSVNLVDSTSSRSSTTAVAVPTIKVTPAPPSSGNGSTATPSETPAATTLPKAYGKIVLTLENVLLPNEKLSPTPSSLDGLDEDNEMDLRIMGCELITTAGILLKLPQTAMATGQVLFQRFYYSKSFIRQPMEPTAMACIYLASKIEEAPRRIRDVVNVFHHIKLVRAGKPIQPMILDAAYIRTKNDVTLAERRVLKELGFCVHVKHPHKLIVIYLQQLTYDNESEFVQLSWNYMSDALRSNVFVRYTPEAIACACIYLSARILKIPLPNNPPWFVIFDTTEAQIVDICENILTLYDRPKVNYEQLEKKLEQLIKAYQDSKQKHRSGTSTSDKAALGTPTSASPLSRPASPQGSAPANASSTEASTVNNGKDKVIDDNKEKKKDKDDTSKAVGKRSAPSSPEPAKRSRRTPSPIVFDDSPKRHKRVDMLTQAQGRVLAHAPERGSLQRNDLVELEVEVDHIHRSVIIITNINHTVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL90</accession>
    <name>A0A1D2NL90_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Hydroxylysine kinase</fullName>
            <ecNumber evidence="8">2.7.1.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00711</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19049"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57882"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58357"/>
            <dbReference type="EC" id="2.7.1.81"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.81" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN06024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL90"/>
    <dbReference type="STRING" id="48709.A0A1D2NL90"/>
    <dbReference type="OMA" id="FYDTFDC"/>
    <dbReference type="OrthoDB" id="9973935at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047992">
        <property type="term" value="F:hydroxylysine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000549">
        <property type="entry name" value="hydroxylysine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1200.10:FF:000007">
        <property type="entry name" value="hydroxylysine kinase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050249">
        <property type="entry name" value="Pseudomonas-type_ThrB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21064">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21064:SF1">
        <property type="entry name" value="HYDROXYLYSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="10">
        <location>
            <begin position="131"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="383" mass="42805" checksum="8940B3CD583D4F7B" modified="2016-11-30" version="1">MSPSGDSGSATLQPGQRIKPNVSLSTAQKLIEEHYGLQIESIKELNSYDDNNFYVKAKDSDENTQKYTFKVLNSMDSKKTGHIEAEHVAMFLLHGKCIRCPIPMKNVKGETFALVNIKNEATDVDNNESIPTESSHIIRLLTFVEGQIMYEAPPTPKLLAKAGKYIAEIEAILKEVACAALDNHSSVWMLSHVLDLEKFIYVIKDQPERFNLVTSVLEAYKNRVVPILPQLEQGVLHGDFNEQNIIIQPSTTEPGEYDVHGLIDFGDLQAGAYIFELAITTCYMMLECVKEGVTLDSFEGAQNVLKGYSTVRNIPDKELKVLRILVASRLCQSLVLGAYTYSLDPGNEYLLTTAKTGWALLDRVWNEKSDEEMMACWKAAVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLR8</accession>
    <name>A0A1D2NLR8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLR8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="20030" checksum="6055BD896BF65DF5" modified="2016-11-30" version="1">MRLRMFGWNSLNIFLMKWIFIAFICKILARIFLRGAINPEEKAAPASKNKLKNSTDYDLSLTSEDLCTLDADELFLHPFRDFLALALCIAWYMLRKRIMLRKQEAVIRKLQFYQKQLEISKKMTKRLRSKLRKQYSKLFDHIFDFQVALGRLHPPPIADSDDDDRDVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNC9</accession>
    <name>A0A1D2NNC9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NNC9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11595" checksum="8BFFB29F1A3A6564" modified="2016-11-30" version="1">MEETPRSHAEQRKSQSWTATGKVESSIISVNSLEFPRQNNSYPSEPGSRTSVTSPESGIDGEAESSDETAPPPVPPKQRDKHSDNKPPTPPPKPPMRYFRDVPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M185</accession>
    <name>A0A1D2M185_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007458">
        <property type="protein sequence ID" value="ODM86729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M185"/>
    <dbReference type="OMA" id="RIWNIDI"/>
    <dbReference type="OrthoDB" id="5960276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="131" mass="14813" checksum="BDF7C858D84FD936" modified="2016-11-30" version="1">MGNWPVNDLLDLRKLSIKLVALLALTTGQRVQTISLIRLVNVKFVMNCVQIAITDRIKTSKPGKSLMLDLPKFSNPQLCVVLCLEHYIERTFSFRKESNSEFLLVSTRAPHGVVSTQTINRNTERCSTPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Q6</accession>
    <name>A0A1D2M1Q6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone H3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_19782</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006835">
        <property type="protein sequence ID" value="ODM86899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Q6"/>
    <dbReference type="STRING" id="48709.A0A1D2M1Q6"/>
    <dbReference type="OMA" id="LMIDLRF"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000085">
        <property type="entry name" value="Histone H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="44"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM86899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11417" checksum="83288555CED2B576" modified="2016-11-30" version="1">MARTKQTARKSTGGKAPRKQLATKAARKMPQPPEVSRSPIVTVPDFKTDLRFQSSAVMALQELRAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M200</accession>
    <name>A0A1D2M200_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_19720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01006615">
        <property type="protein sequence ID" value="ODM86962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M200"/>
    <dbReference type="STRING" id="48709.A0A1D2M200"/>
    <dbReference type="OMA" id="WEYISVD"/>
    <dbReference type="OrthoDB" id="115435at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000026">
        <property type="entry name" value="Transposon Ty3-G Gag-Pol polyprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="7">
        <location>
            <begin position="172"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="8">
        <location>
            <begin position="716"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM86962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="873" mass="100424" checksum="3B51762DD89942D5" modified="2016-11-30" version="1">MNLNLKGLSNTSIKPLGECNLKIDIGENCTKSAKALIVTDMSFDLIIGHETMKAWELCIDYATNEVIIDNKNVNKENGITAFVQIIEIEYEDLKKRFREKVSPNLTLTQQEKLINVLMENKEAFSVNGELGLVKSKYCKITLKSDSQPFKSQPYRVSIAERTIIKERIDELLKKGLIRKSCSDYTSPIILVSKGHKDSSGEKNQQRLVVDLRRLNKIAVNDNHPVPYMDSTLEALAGNNYFFSLDAEKGFWQLELEEASRKFTAFVCWLGIYEWTVLPFGFCNSSAIFQREMEEMLQDLLYVVCVVYVDDIIGFGVTFEEFLRNLEEVLGRCIKYGLKLKIDKCSFGHDEIDCLGHRVGKNGIKPDPKKVMAIQDIRTPSTIKEIRSFLGITGFFRKFIPQYAQLSKPLTRLLEKDNPFLWTPEQKRAFEELKSRLCSAPILRPFKAELRTILHIDASDYGVGSTLLQEEDNEERVVGYASRMMSSAEKNYSVTQKELLSLIHALKTFRHFLHMRRFEVITDHLNLVNMNFAHDVSCGRLLRWAVRLQDYDFVLKYKPGRLHNDADGLSRLPITPKFLPEEDSAHEFPIYSISIEENEKLQLQDTFCNNIRELLTKGDKRAVKRFTIKEGRLYNVERGNLRYVVPKTLVHALIYAHHGSETMAHVGFGKIYDQIRSKFYWAKMKATILKEIARCKTCKTAKHSTQRRYGFLQPIEVNEVPFDLWGMDFFGPVTTSPNGNKYLLVAVEYLTKFVLARPFSNANAEAVVTFLQENVIPIFGAPKAILTDRAKIFFSGDVRQLCTKWGIQQKYTSGYHSAGNGMSERMIQSITTLIRCEIENKQDEWEDALPVVLHLHQRQRSNLTDWFSALNQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M280</accession>
    <name>A0A1D2M280_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein PNO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19612</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006227">
        <property type="protein sequence ID" value="ODM87070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M280"/>
    <dbReference type="STRING" id="48709.A0A1D2M280"/>
    <dbReference type="OrthoDB" id="1932641at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22391">
        <property type="entry name" value="KH-I_PNO1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000009">
        <property type="entry name" value="RNA-binding protein PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000048">
        <property type="entry name" value="RNA-binding protein PNO1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055212">
        <property type="entry name" value="KH-I_PNO1_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="99"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="632" mass="72802" checksum="DAAD8D0350DA409B" modified="2016-11-30" version="1">MEVDVGGPTESTGKYELRKVSVPPHRYTPLKQKWRDIFTPIVEHLELQVRFNLKTRNVEIRAREDVKDASYLQKAVDFVQAFVYGFAVEDALALVRLENLFIDTFQVEDVKPLKGDHLSRAIGRLAGKGGRTKFTIENATKTRIVLADSRIHILGSFENIQLAKRAVCNLILGTPPSKFRFQVICGINYVGTKRRDPAAPAKNIILDNEEKEETPQTEKTMDDLPPEVLTTILEHAILNEPRNHVLVYRLVNPQWKEIVESLLEKEVISRRLEAFPEMKIGGQSDQLSVYCPRTIFRPEGNPFSFNSLLLDGYKHFRQDPTDTQMALPIFISKFGSNLTTFALQDQIIHKIAGYDAQIHEQLEEYLLRRRRTNQEEHWTRGILEPPPLPSLSTLKLKSELYYEEEDTKINPLYVWLVASYADQLVHLCLNTSGPFPALQKGHTNTVLRGEECKPSRITRLEKIDWHLWKLSPGSLLGHRSDALVNREGIQNIPTTRVIAGNVKKLTVRFSDDEDETLIDRALLTMFPGLERIQLLFYYSFGLYWEMTRYECQHQGANQVVSKMNEGDPADEILALKRRLLPLLEQKAVLVMRYRDPAEIEVRDQIYEAITAARSERASIFNDWLLWVKMRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2M1</accession>
    <name>A0A1D2M2M1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Proton-coupled zinc antiporter SLC30A5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Solute carrier family 30 member 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Zinc transporter 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_19475</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>Zn(2+)(in) + 2 H(+)(out) = Zn(2+)(out) + 2 H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:72627"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Heterodimer with SLC30A6/ZNT6; form a functional zinc ion transmembrane transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasmic vesicle</location>
            <location evidence="3">COPII-coated vesicle membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasmic vesicle</location>
            <location evidence="4">Secretory vesicle membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005903">
        <property type="protein sequence ID" value="ODM87206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2M1"/>
    <dbReference type="STRING" id="48709.A0A1D2M2M1"/>
    <dbReference type="OrthoDB" id="78669at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF1">
        <property type="entry name" value="PROTON-COUPLED ZINC ANTIPORTER SLC30A5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0050">Antiport</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="11" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="23">
        <location>
            <begin position="112"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="398"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00038531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00040846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODM87206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="46320" checksum="1CC08C503AEC24D1" modified="2016-11-30" version="1">MPKLHEIGTSSVMFAALLYTMLWTTEETPSTTTLMAYLLIYLGVLSLTSMEKASGGGSFVGYSSDGLPLFSFSDHFSPETYVPMWRNILKSTSSVLKQIQEDAISRRLFYFSVLTMLFTGIEFLYGTLTNNGNPKTYPFGYGRIEVLSGFLNSFFLLVIASIILIEALQRLYDPPGVDAKRLLPISIIGLLVNLVGIYTFRSNSAVSHGHNVNVKGVFLHILADTIGSIGVITSSILIHNYGLLVADPICSMIIATLIVISVVPLLKETSKMLLLAVPSGLEKNLQQTVLQILTTEGVKGYRNPRFWTHAPSVFTGSIHVQATEDANEQQVIRQVNNLFSSIGFTHFTTQLEKDEFIARKSFSIDYETRTTSESDMDVIHGSRLLLENNSLEGFGSETKYSSDSSVTQTGTEQDVKITLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M394</accession>
    <name>A0A1D2M394_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysenin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005304">
        <property type="protein sequence ID" value="ODM87443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M394"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903418" evidence="1">
        <location>
            <begin position="37"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="13983" checksum="8D99D2314B1146A2" modified="2016-11-30" version="1" fragment="single">MKKGRTCHKMRAQTNSSLMLWLAIVFGVLFPDRDSADQKETPQKAAGLKNGNLKTRTKWATQSISGPISISESKMAKCYSHNSEENGHYQVTLGDMELENEISSTDSGIIAPCFCTSWSLSITRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3H8</accession>
    <name>A0A1D2M3H8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coenzyme Q-binding protein COQ10 A, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005106">
        <property type="protein sequence ID" value="ODM87527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3H8"/>
    <dbReference type="STRING" id="48709.A0A1D2M3H8"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="5">
        <location>
            <begin position="58"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="24816" checksum="C0BFA273DFD7794C" modified="2016-11-30" version="1">MIKNCIQQANFLSFPGGSSTATKRKQFTERRIMGTKSGCFKQNAHPNNLFSLQIWMEQMFDVIRCRKISRLLTVVPFVSGNVQRKRFLERKFSSGDTSFCRVIHIQRYARRPLIIKAESTKGKLFKELTFVWKFSPGLKGKPQSCIIDYNVSLEFRSTIASQAANVFFNQVVRAMTEAFYNEAKKRYGPESVPSRKIEIVGSSSNSSDDDSSGGPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3K5</accession>
    <name>A0A1D2M3K5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_19191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005171">
        <property type="protein sequence ID" value="ODM87491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3K5"/>
    <dbReference type="STRING" id="48709.A0A1D2M3K5"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="3">
        <location>
            <begin position="411"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM87491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="567" mass="63849" checksum="CD499FB66CC1D608" modified="2016-11-30" version="1">MPVKHFVTSSQCPKDTGILDYHEINCSLGGAGMVVATRIANASRSSQILLLEVGGEPSVLNEIPAFDAYLENQPANTWLYNSTEQTNACRNCDGKVSVNFLGFMLQTFASINDLKSMFTQKVLTTRGKMLGGSTSTNFMMYGDTQWNYENLLSYFKKSEDYNGAWASQPDALTYHGKGGLRNVGTYDFQPGVDEFLAAALEKGYILGDYNGANQEGNYFQRLMSQLKTAGERVHTALSTETRGSEQPLHKKYARVTKINFLTLLGHQKLYNVNVVRDCDRNQRGYPQRWNFRFCSVVDDIRRRPAEHLSSLNIPLVKDLPVGKQLSDHVTTLVALSEISRVNPNRDLTIQAATEFLTSPTMLIYKWSTLQHLFIPSYPRPEQNVWTRVDILESWFDPTTNKIFGLLILGRPKSVGELRLASTNPYDNPIMDLQYLQHPDDVEAMLHGFKIFVDLYENTAALDNTKLFEKPVPGCDQNFKSDDYYRCVIRSFSFSIYHHVGTCALGKVVDGRLNFKYLINSFFQCRVIGIDGLRVIDASVMPRLPNGNTQAATIMIAEKGSDLIIADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M465</accession>
    <name>A0A1D2M465_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004718">
        <property type="protein sequence ID" value="ODM87768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M465"/>
    <dbReference type="OMA" id="ICTGSEC"/>
    <dbReference type="OrthoDB" id="7971529at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37162:SF10">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37162">
        <property type="entry name" value="HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="42964" checksum="7E4DBCA7126C892C" modified="2016-11-30" version="1">MSVNINKRARRQCTFNAELAKDYPFLEKRSNLSDSEVYCKLCNHSFSIANSGRTQINNHINTEGHKKNERAQASSKQLNNFFPNLKAKKEDLDLAAREGTIAYHTVLHDHSFNSVSCTSKLLKSFYDQKFSCSKTKCERIVIKVLAPAAIEVVEKELANVNYINAAVDCSNHKNVKLMPVMIRYFTVPEGVKVRMIDIHSLPGETAEIITTAVLKTLKEFSLSDKLIGICADNTNTNFGGVNRKGKVNLFSWKEIENSLETFTAFTGSKLNENELLDEFACLNEYITKEKIADWDKKILNADLRWADLYREQMHQLNVFSLINNYWSAEKVNLSLETLNAAITMKVNMRMDCSEYYAYLKSDTELLKKIHSAEKYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4C0</accession>
    <name>A0A1D2M4C0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Niemann-Pick C1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_18862</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>cholesterol(in) = cholesterol(out)</text>
            <dbReference type="Rhea" id="RHEA:39747"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004637">
        <property type="protein sequence ID" value="ODM87820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2M4C0"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015485">
        <property type="term" value="F:cholesterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042632">
        <property type="term" value="P:cholesterol homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030299">
        <property type="term" value="P:intestinal cholesterol absorption"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053956">
        <property type="entry name" value="NPC1_MLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22314">
        <property type="entry name" value="NPC1_MLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903457" evidence="14">
        <location>
            <begin position="27"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="698"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="728"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="771"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="805"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1164"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1190"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1222"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1254"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1293"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="15">
        <location>
            <begin position="697"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="845"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM87820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1326" mass="147382" checksum="4195B6E88FAEE0BD" modified="2016-11-30" version="1">MERFRVIILLVISAFLLVLDTPFVSSLETKILLDNGSAAGASKAQCVMYDECGPSPLNPDLNTNCVYNGPPKKLNDSEALNTLQSMCPEVVEKYGDELCCSATQINTLQGNLALPQAIIGRCPSCFYNFRRSICELACGQSQSQFLNVTKMQKNDTTGIAVVAEIHAYVTDYYVTETYESCKSVIMSSTNQLAMDMLCGPWGSFHCTPQRWFDYMGSTSNGYSPFDIIYNYSYSNYTGPFSPFSPEKAFKCNERIDNVTSACGCVAAMHRVQRLNPFRIWCHQHGSYLDDKSASRNVEQPNGQIRSNNQSHHDQNRLLPDGEILAMYPMDSFSLFQSAQQSIKKLFCVVGKGSAAHPVLTLFLLFIPLILSTSLVTPLFKITTDPVELWAGPHSRTRVEKDFFDKNFAPFFRTEQIIISSSNPSFNRTNADGQNQTFGPVFEKKFLYEISKLQSDIESLNGGELKSICLKPLETNCTIFSLMEYWQNSLVNLNKTESNDTYLDHFLFCSKNPASMADSTHLRQSCMGKFGGPVDYKLVLGGFPNDSEEAYLLANTTILTFVVRNHLEDAFNEEAKVWESAFISYMENWSATHEKKLNLSVAFTSERSIQDELSRESRMEIETILLSYIIMFLYIALSLGFGSYAVELFNRCTWRRYFWWRQINRRTSGVNLIEEPVPESTPRLPQSQTRRNNKWLPRLLLSLAGVFLVLLSVTASIGLFSFAGVPATLIVMEVVPFLVLAVGVDNIFIIVQTYDRTFPNSDLPVPERIGQVMSDIGPSLLISVISESVCFFIGGLVAKMPAVETFAYYSAVALIVDFLLQITVFVAIFGVCEEMGNVKNYSHEVLTNDSEEPSTSTPSPNHRPVSSIENTSPNGGGLQKEPINDQGGYITQLFTNCYAPFILGSKWIRLAVLMVFYSWLCVSIALVHKVDVGLDQKLSMPSDSYVLKYFNSLAEYLQVGPPVYFVVASNSSSPSLSDWDVQSKIAASGSPSSLVSQIFSASKISNSSFIAKPASSWLDDYVDWAANEDCCKITADGQFCPNSNSSCGPCGIEVTDLKMSPEDFRKYISFFLQDIPTETCPKAGHAAYQNGVSLGTVNNQTEVVASYFMTYQTVLKTSHDYVSALKQAIFLSENITKTLNNEFLVFPYSVFYVFYEQYLDTWHQVLLNLGLSLAGVCVVVLIGTFSIKETILVFTTILCIISNLIGMMYVFGISLNALSLVNLVMAVGISVEFCVHIVCAFAHTDGNSNVEKSKIVLGGVGSSVFSGITLTKIAGIIVLGFAKTKIFEVFYFRMYLLIVLIGATHGLCFLPVLMSFVGGGKREVARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4H6</accession>
    <name>A0A1D2M4H6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative arsenical pump-driving ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004511">
        <property type="protein sequence ID" value="ODM87873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4H6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903464" evidence="1">
        <location>
            <begin position="27"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="17815" checksum="F046A6BDAFA6D69D" modified="2016-11-30" version="1">MRCHLMMLIVVLPVLLSSLEIQLAEGIKCYFVECSGSACVGKGVEMDCEANYDRCFESLRWMTLSNETRIDRSCSDKETEDHVKEIGLSCEDFRPVKNGSTTLSKQCFCYADLCNDKFTDFGLVTTPAGLTNDAPLITGHSTVLLLVIASIYRLSSIFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4N1</accession>
    <name>A0A1D2M4N1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004395">
        <property type="protein sequence ID" value="ODM87929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4N1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="388" mass="44642" checksum="D2C23AC5B795D3B5" modified="2016-11-30" version="1">MWEESFYSSSSSISKEISPCLLCACGTKSRIPIDKPNHHESTHQQMFNYFCKILGMKEPSKIWNFENEKVFPFCAICKALLNTLVEVYSKLEELERVIKARMNEGEKTFVGDDLYGKCDERYLKFRKEAREGNVMSKSGETLGEIFTSDSESELGALSNEPKGSVNLQREKVSFTSTTKQRRKRKKTSSDSSTSSSSDSDTSESEFSNKRKKKIAKPTPSQKPNPNLILHSCRLCRDNPGFSSKELFNKHLATTHKVSSSKEYAQMNATLANKNRDGRKRYHTEKGWVTECEICSKQFININCRMSEWKHHQLTHKSGAEEIFLKNMRHGSKAKSTELVKFMKCYFSDALAGLAERCWCKIWTKSRRMKYTPSFGVFYLIFNNFLCDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5P0</accession>
    <name>A0A1D2M5P0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_18452</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003938">
        <property type="protein sequence ID" value="ODM88231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5P0"/>
    <dbReference type="STRING" id="48709.A0A1D2M5P0"/>
    <dbReference type="OrthoDB" id="9439903at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000478">
        <property type="entry name" value="Zinc finger protein 133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="306"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="234"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="500"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="534"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM88231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="544" mass="62286" checksum="66B4AE6D87C76AA0" modified="2016-11-30" version="1">MGDASRQNLIPPAGPSMAPTDEELQSQLSHIQMAFNRNWEYKERALKAKVDELQKALDSANAKETKRKAEMEETKKWVVEELKLLLFNEDSKNGTELLKEKLKNAEVVMDNGFRKRAEYRRIIREQKLKISVLETTLEETESGLRKELQVQHDEVQGLQRRLELAQQKTRDYLHQVLLEMEGEADLNREMPVAEGENSGESEDQGQNLEREERIWEWGVLIIWSSQLSQNQQRIRENEEGASSQLVPVPVAASSSNNPQLPRRSTRRRNILDRSKNPAEFYQHGEKRRIKMSYDHVNILGENPPLYQCKKCHRKFKSTRSIYNHMYCQSEDADKPFQCSQCGKGFVHSSNFKYHLKIHSGERPFVCVVCKRGFIQNCNLQSHIKTHTVFSTDDKRKSWAVQEQRPRCMMIGRDRPSETSSMSSVAHSPQHSFERKRERGSVSVFGFWWNGLGSGGVYQSSGRKSEQQLNQAEYFAHAWQVARYQSTGGIGDVGARSEGQITGRGLGSGYGSQSEGGVNFSEGDEALNRQGARSKTTDLLRRLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5Q3</accession>
    <name>A0A1D2M5Q3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Acyl-CoA Delta(11) desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_18377</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The histidine box domains are involved in binding the catalytic metal ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003790">
        <property type="protein sequence ID" value="ODM88305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5Q3"/>
    <dbReference type="STRING" id="48709.A0A1D2M5Q3"/>
    <dbReference type="OMA" id="IGYHRLY"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="14">
        <location>
            <begin position="65"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM88305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="45171" checksum="3114E05F84CE6C5A" modified="2016-11-30" version="1">MCVTKKEKLLEVPVERKVHEDFSRIDKPFGLEQYIFNWIWLGSAHVFAAYYFYLDIAGIVPTSTLLFELLYGYIGGLGITVGCHRYWTHKTFKANKPLQILMMIMQTIANQYPIRKWSLDHRIHHKYTDTNSDPHNSKRGFWFSHMGWLFLPKHPDLQKKLKTFDMPDLENDPIVRFQSRWYWTLTAVIHFIIPIFIFRYFWGLTWIYCIAANYRRYVVSLHITWSVNSVAHLWGDKPYDKNITPVENPWVSFFAVGEGWHNYHHTFPWDYKSAELGWKINFSTMFIDFFAWLGWAYDLKTVSQKMLKERLHRTGNESHNLQQSEAICDNDTNDFDYSVPADVTQLMKDSINEPIWGWDDESIPEDLRNVTKTLRSKGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6Y1</accession>
    <name>A0A1D2M6Y1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF659 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003273">
        <property type="protein sequence ID" value="ODM88728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6Y1"/>
    <dbReference type="STRING" id="48709.A0A1D2M6Y1"/>
    <dbReference type="OMA" id="FENDSCY"/>
    <dbReference type="OrthoDB" id="6777440at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007021">
        <property type="entry name" value="DUF659"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04937">
        <property type="entry name" value="DUF659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF659" evidence="1">
        <location>
            <begin position="33"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="36050" checksum="C7273F992B4F5D3A" modified="2016-11-30" version="1">MVELLRKLRPAYFPPNRKLIGNEILEEVYMETDRSDCKKEVTLVQDGWGTNQTQPVVAHSVHSGSKAFFLNAVAPGSATKDADYCLGVLSAAIEECQNVHKCQVIGFVTDNCNVMLSLRNKLHESHPDIFVFGCNAHYLNLVGQKVIPHDKIDNIVKIQKYFKNHHFQSAALSAAKGKRPVLPGLTRWNSQIDCIENYIENHAIYLDLRVKIRKFDNNITQMINDFSLYTAAEKLKSLAKPIAVALDKVQSNSASLSDAVSEWIKLRNDCPFENDSCYTYFQRKLTEALNETALAAYILDPRYRGNGTLLLRRRFKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8M6</accession>
    <name>A0A1D2M8M6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_17356</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002720">
        <property type="protein sequence ID" value="ODM89325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8M6"/>
    <dbReference type="STRING" id="48709.A0A1D2M8M6"/>
    <dbReference type="OMA" id="INESHQC"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM89325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="307" mass="34652" checksum="72DCCBC50706C8A5" modified="2016-11-30" version="1">MFTMNQTVLSGLFFAPSLRHVAPDFFGWTSWVNSVKNFFAVTDQAIEAHSVKLDLNNPQDFIDNYLMEIRATQDPSSTFYKENGEKNLKAIVGDLFFAGAETSSTTLSFAILYLCQNQEKQRKAQKELDLVVGSSHQISLSDKLSLPYIEAIVMETLRLSSIVPLGIPHQLIADTEFHGYLLPKGITLMPNLYTIHHDKKIWGEDANLFRPERFLDEDETRVVHNDALIPFSAGRRQCLGEGLARDTIFLFIASILQNFDIGPDPKSPVLDMETIPGILVEPKPFNFSQKRFTGTIRFASNQTTNMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8U9</accession>
    <name>A0A1D2M8U9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002656">
        <property type="protein sequence ID" value="ODM89416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8U9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="381" mass="43668" checksum="362604276EE89D5A" modified="2016-11-30" version="1">MDWFSTRFSTIVTGIKPYINSSSSSENITWTATMVARLNRENDFNPSFQPLQVIHTVYPEMANLRDWLLYDPNLKQDVNLEQPLEVAQEANAIFPGTVTTIVFHKADSRFGWNGFKEALETQLGNTNNSNAIRFGTYVDLSNCEVLKADFKSVSKWLKVVIIELVSDLRSPIPRLQFNNQKAAAYMDSALRNLFGKWEECRDSFHAVYPEVDIMLAVDCSKVMRTHENTTKEQLAKCWEMVTDYAEENNVWVVLYQAFDTPCPLRAPLGYRYVHDYTKGWWKLQQKSQVNITADSFEEQFKDLTSDSVNSNKNIYRTATLGTKCEAGGRKNVSMIVAIVILSILCFGLIMAVVYLYNGNIFRKLAQRDHVKFQVLSEDVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAC5</accession>
    <name>A0A1D2MAC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_16732</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002276">
        <property type="protein sequence ID" value="ODM89948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAC5"/>
    <dbReference type="STRING" id="48709.A0A1D2MAC5"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050636">
        <property type="entry name" value="C2H2-ZF_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="384"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="472"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="579"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="633"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="476"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="582"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM89948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="674" mass="77870" checksum="243973C667D9BD0B" modified="2016-11-30" version="1">MVHTEKNKERQQCPKCPLSFGDMRKFWQHVVLVHETQGDEDGGTSSNEENPRLDPRVNTMWITAEDGEPTCKECNKKFANVKGVKKHIKDIHLKLTFRECLRCGQKFRDTHNLNRHMKDVHSLSATDFPCSLCSIVYCSADGLFRHKRTVHGIRDLPATSGTPPTQCPYCSEIFYHQGFETHIRELHSEHYEEYLTSVMKKPQGTGRQPSTCQTCGLSFSDVQTLRRHITRVHDPSGKFQCSECGKHFGDQKELTTHLAMHQNAVMEPHIKAMLRSVFGTVCSPSMTCGICQTVVDSSVEAKLHLYVNHPDKFKEMIPSTPSGTGFVCTVCSVQQNTKEEMIQHMELYHQEENLPTCGICGHKELKERDMNYHYKRYHSEATRYVCDVCQESFTQKRELEKHVKREHTDEAGQCPYCPEKHIKVKMHVTKMHPERAVEYRKLVDQAIKEEREARKRFNQFLEGKNIRNRKRRVIDGDDSDSDSDKDEELSDDNNDGWNGEEGELEKKPIPSDCVVQQTKPVTLEKYKIEKKPEQPHVIEIQRIVPPAPDPEQILPDDCDGEDEQDIKPNVHALNEEQLQLQGEDEDEQIQEDAENEAEQIQEDEEEVELDEEEPRYLNLVLYRKTLAVEVERLNESEIKKWTSSASSSTTAKRKSPGNNQNAGPKTKKRRKRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAG1</accession>
    <name>A0A1D2MAG1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16721</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002270">
        <property type="protein sequence ID" value="ODM89960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAG1"/>
    <dbReference type="STRING" id="48709.A0A1D2MAG1"/>
    <dbReference type="OrthoDB" id="3069995at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="293" mass="33944" checksum="870A7391044D1B8E" modified="2016-11-30" version="1" fragment="single">CFIKLKRLKSCKLPSSSSSRRQNRGTKSPKTIRNTASKKEYKCTICFKPYRSYQGLAHHKRSHTNERPYGCKIVPEILNPQSIQTLKSHFCPQCPASFALSSGLRSHIRVVHEKDQRTKRKCNICHKILAKSHIAAHLKCHAKKMPFACVMCDKPFYALNNLKLHIQTKHLQERPFSCSKCPATFPVKYNLTHHILRVHIFDEWYTLKCVCDKTFHTEYALNQHMTSHTGEKHYKCATCGKRYGSSADLQRDVVSMNTFLRTRERNRFRISCARLDLAKMFPYIPSGGIQNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAP6</accession>
    <name>A0A1D2MAP6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002188">
        <property type="protein sequence ID" value="ODM90066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAP6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="59013" checksum="95866612A854FB3D" modified="2016-11-30" version="1">METFSKLSPETGSSLKVEEEENKGKSDTNMSQDGDLFSQLNVFSILPELWDQILNNLSPTDFLAIINSSLQWRNMFKTKTTDLLLPLVLNVLLKHWAVSKKSVLNWRQVNRKAKLFIEGRLEESPQQFYKNRDHDQDMDLSMWSSKRQVRNQPLGEIIEKIKNRYDFKYPSEMEQFTSRLATTGLSNPFLTKSLSVFILDQRYRSDKHLDLDPILMNMMSKFGHGISTMTFDLAGVNISYFFSLLGHISNLKVLKMNGPFILFPEYEDEMLMDREWANLKHLEILDIEKFRENMRPQNSRTGGLCTALLGRCCTQLKILICSNDFFGIEGNVNLLNSTSLPNLRCLRVSKADASVFTVLSEIKGLHLAEMQFVNCWDRDVHTIGSVIRAVDNFSQTLTHLQLFFKLDKGDVNLMLQESNWTKVLPKLSAFTTYWQNVDTSWFNSFIQHKCQNLKVLSLHGNYFVEENKMFKRTVKIVSQLKLQKVVFCCEIEQRKHSKAKNPVSNGTWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBM6</accession>
    <name>A0A1D2MBM6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002051">
        <property type="protein sequence ID" value="ODM90294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBM6"/>
    <dbReference type="OrthoDB" id="8272841at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006170">
        <property type="entry name" value="PBP/GOBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01395">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="104" mass="11320" checksum="541C707622B0D207" modified="2016-11-30" version="1">MAPSEGLTDKLKNCNDPEIVGDKDPKCIAVCTTEAVGGLKDGIPDKDLFINLVKTEFPEAQQANALERAEKCFEDRTFDKEDKTCSSIAEFSVCGTKLVVETTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCH7</accession>
    <name>A0A1D2MCH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001851">
        <property type="protein sequence ID" value="ODM90680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCH7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="96" mass="10779" checksum="78522BA09B48E829" modified="2016-11-30" version="1">MTRALEPSRRHRFHSSLGNGMLTFEGLGRLYWRCSEQRQQSTIQEIGALNALWVVAVSCSVVQRLMTIIIWMLNAVKLLQLRIGIAGVVAGCPQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCL8</accession>
    <name>A0A1D2MCL8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001814">
        <property type="protein sequence ID" value="ODM90738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCL8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="50265" checksum="9E0AB97A2AFE4ADD" modified="2016-11-30" version="1" fragment="single">MKAGAVSPVSSSAERMWCEDGFPDGGLSEIWLNVFDKLDRTDKLAFSAASSVWHDWVEPKRTESLISEVAPQLIETFHSENLLLGRELCQSWKEELEYKIQTNPSHTSLYFEIDSGQHWIPDLRSFRFRSVLSTVEKVESFMREMTNNPGNPFPARSIDLHCNFSEEVEGPEWNELQPEQLTMDSHVQLRECLLRLPNLKQVRFSKMDKSLLLENWIRDYYRLNPLPRLEHLETVQLNSASPALVGEVVNSCCVPANIKRLSYQHGQWHAHRGELPEVVYSFVNLKVGNLCGDSYSVRHGLYDPRAKWGEFSCNLPNLKKLSIHFYVGPLELLFQFKSLIHLELFRIRDSNGEWLDGREKQPVEERLGDNSVENWILKDLSEDLVSGLPVVVSGVGCLVYIVEVMQQLCFGSYSVMKLWPSISFIGFWFFHCEVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDM0</accession>
    <name>A0A1D2MDM0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001681">
        <property type="protein sequence ID" value="ODM91075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDM0"/>
    <dbReference type="OMA" id="HTRISMM"/>
    <dbReference type="OrthoDB" id="8279820at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903863" evidence="2">
        <location>
            <begin position="17"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="20819" checksum="B8FA45E112953E7F" modified="2016-11-30" version="1">MKIVLVFVGLIALTYAGVGVVTPEVEREAERLWKKFCEGASEGGNDGDLAVYCKLSRDSYEESLQHQIEVTPPPQALNRWCSSVHQHTRISMMWWLLEEVLPVRRRLFTFCPSKNKNQVNLVDNTSNTVVTQKPTVYFLKKDHDHSKSQEEVGSQPASPPGGYLPPPKEPDNGYNYQPPRSGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEJ8</accession>
    <name>A0A1D2MEJ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001608">
        <property type="protein sequence ID" value="ODM91281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEJ8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="82" mass="9419" checksum="E2C37820CF530915" modified="2016-11-30" version="1">MGQQGTSMLYKVRTVSIFCVQQLMYLFGFWIASLIMMWKMRTAAQKKLSSSRADEPANPQYETKSEPTIRYVDTGVTKRSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF41</accession>
    <name>A0A1D2MF41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001532">
        <property type="protein sequence ID" value="ODM91491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF41"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903926" evidence="1">
        <location>
            <begin position="25"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="29206" checksum="ACF97D90C1C62161" modified="2016-11-30" version="1">MTSFWGIVPILFLWTFFFFKQVECQLGVTYTPFVTPWDTSPTTQSYSIEDVKVMLNIISEDNFPFVSTYTVGAPNGNIINNPEMFKKTKNQIIMILLQNITKQTKTRYRCSSVFHTALAAAEINKEQKSLALTVYQGLYRHSPPAQLISEIEVGFEIAQAANQIYPGTVPAIIFPSSAGFNGLFDMEENLKAVSKRARNLQLKFGVRISNCETTIGKPDNYHKNKELLTLFDFLICEFMPKNELFRRTRKHFLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF75</accession>
    <name>A0A1D2MF75_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15129</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001506">
        <property type="protein sequence ID" value="ODM91552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF75"/>
    <dbReference type="STRING" id="48709.A0A1D2MF75"/>
    <dbReference type="OMA" id="VYVENIQ"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="10"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="224" mass="26128" checksum="E33454456097E8FE" modified="2016-11-30" version="1" fragment="single">MIFRSRRVKAGLSSYVFRWSGGMIPYKIQRGLPEEMHQMLHQAMSIIEDHTCINFIEKTTEKNYVYMSYSEQGCFSHVGMVNRGRQKLNLGRGCWKFGTIVHELIHSIGFSHEHQRNDRDSYITIAYENVEEGKEHNFKLDREMGLEFSTYEIPYNYASVMHYGSMAFSDEDDEPTIIPKKLSEVSPKQVYYSAVDGDGRPVIGLRKLTWGDVRMINLMYKDHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFI0</accession>
    <name>A0A1D2MFI0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001474">
        <property type="protein sequence ID" value="ODM91621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFI0"/>
    <dbReference type="OrthoDB" id="8284886at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10800" checksum="9BDA532991BB79E9" modified="2016-11-30" version="1">MAKCTNFVRIFDIVIPGTRDWDCPIKAWLVNGCVIILLGVISLLVLTIVTNRLVYSLLFFLMSLRIYEIWVVFDFCETQDLLPSNHDVEKLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFI1</accession>
    <name>A0A1D2MFI1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="19">2.4.1.223</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_14968</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>3-O-(beta-D-GlcA-(1-&gt;3)-beta-D-Gal-(1-&gt;3)-beta-D-Gal-(1-&gt;4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1-&gt;4)-beta-D-GlcA-(1-&gt;3)-beta-D-Gal-(1-&gt;3)-beta-D-Gal-(1-&gt;4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16221"/>
            <dbReference type="Rhea" id="RHEA-COMP:12573"/>
            <dbReference type="Rhea" id="RHEA-COMP:12574"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132093"/>
            <dbReference type="ChEBI" id="CHEBI:132104"/>
            <dbReference type="EC" id="2.4.1.223"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Glycan metabolism; heparan sulfate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.223" evidence="19"/>
    <dbReference type="EMBL" id="LJIJ01001446">
        <property type="protein sequence ID" value="ODM91713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFI1"/>
    <dbReference type="STRING" id="48709.A0A1D2MFI1"/>
    <dbReference type="OMA" id="KFMGSHT"/>
    <dbReference type="OrthoDB" id="5954868at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001888">
        <property type="term" value="F:glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015012">
        <property type="term" value="P:heparan sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000033">
        <property type="entry name" value="Exostosin-like glycosyltransferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015338">
        <property type="entry name" value="GT64_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261">
        <property type="entry name" value="ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261:SF4">
        <property type="entry name" value="EXOSTOSIN LIKE GLYCOSYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09258">
        <property type="entry name" value="Glyco_transf_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="20" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="17" id="KW-0464">Manganese</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Exostosin GT47" evidence="22">
        <location>
            <begin position="186"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 64" evidence="23">
        <location>
            <begin position="670"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="20">
        <location>
            <begin position="64"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00050948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF09258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODM91713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="926" mass="107086" checksum="28B0A96C9D4D40F5" modified="2016-11-30" version="1">MPYIRGFGTARLDHLLAGIRKLTFNIEVSVDENFSSEQDINSHPWIVQLADVDKLKGVELKSRIEELLRIKFSVTSELRELEAKRQHVQSEIALLNRRLEEAKMEAGKRRNELDRLQISLQQAKVAEKEAMERNTPRLGRPKPLAPLRNIPTYPVLPEYNSKTPNNFIKYCQMDSCFDYSMCPISSRFHFYVYTMTAYANQTKTMFSGNEQPTSNSITNLQEVLRNNQYLTRDYLKACIFLLIIDECEPVKMAQITKRLPHWFGDGRNHVVWMSCSNSGSYKEVLQSDYLKNFGRAIIATETIFKDSYRTKFDLVVSHWKKTLPSGEIWTHLPSIVPAKRKYLATYLGGETDHYVQSELLKIQQDDPQSFVFQFSCNIPLYQGKKPTQSEENEINSGNFKGEIDKGGKNSENSANGKLSSLCENDLLRTRLLIDSTFSLIILPPEDYMILSSDILQLRLYESLKYGAIPMIIGNRFEPPFSEVIDWSRIIITLPSARITEIHYLLKSFTDTDLLALRKNGRLAFENYFSTMEKVVETLLATLRTRIGVPPNPYKDFPSPSVFNETFVPLKLDTFTVDPEEEENLGPIEPSYPSLSFARNYSTIFLQKYEFWNTYFQPFKLYPYTPWDLTMSSEAKFRGSSLGFRPIAGGAGGSGKEFSQSIGGNLPKEQFTIVMLTYEREQVLMNSLQRLFGLPYLNKVVVVWNSPQNPLPDLRWPDIGVPIHVTKAHKNSLNNRFIPYDVIETEALLSIDDDAHLRHDEIVFGFRVWRENRDRIVGFPGRYHAWDQNFGGWLYNSNYSCELSMVLTGAAFYHKVYSYLYTYEMPSAIRDKVDELMNCEDIAMNFLVSHVTQKPPVKVTSRWTFRCPGCPVTLSEDDSHFQERHHCINFFSQVYGYTPLLYTQFRADSILFKTRIPHDKQKCFKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFQ1</accession>
    <name>A0A1D2MFQ1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cubilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001445">
        <property type="protein sequence ID" value="ODM91722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFQ1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="24477" checksum="A1D888668C6FD244" modified="2016-11-30" version="1" fragment="single">MMELTDANGNELFNSPNITALRRLYSYSSNQYTSQSREVYIIFYSDSAVVGDGFSISWRATGDHIKRGSEITTQFSHYRSDNGSATAVSRTATFTASLYQVFIFTPFLPSTYSDGMQLELNQTLPVVGGNDCVLNELSVYIPVNGILSKTELACNDAGKAILQNADGMVVAVMKSQNVSLKEVGIDFNWERGNALISPNLTMQNVSFDENSARRTKDGSNSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFU6</accession>
    <name>A0A1D2MFU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Valacyclovir hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001389">
        <property type="protein sequence ID" value="ODM91876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFU6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFU6"/>
    <dbReference type="OMA" id="YTIICID"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331:SF2">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="233" mass="26477" checksum="C20F54BA406002AA" modified="2016-11-30" version="1" fragment="single">MDIKPILSALDKEKFRWIGWDPPGYGKSRPPKRQIFPRGYSCMYELDAKYATELMKKLGIEHYSIAAWSSGGVTGMTMANRHPEQVSSMITWASYGFLGQETNKRLKSFSKLGSYALPDARRIELIEVYGEKLLHEMYSDALTEIMGMSESNVFREGGSFEDVIKNVKCPVLVIHGDKDTFIPISNAHHLNSTFQNSRLHVVKNGTHNLHLKQTHEFVKCIEGFLTAVYTQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG19</accession>
    <name>A0A1D2MG19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Matrilysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14767</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Can bind about 5 Ca(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M10A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001379">
        <property type="protein sequence ID" value="ODM91915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG19"/>
    <dbReference type="STRING" id="48709.A0A1D2MG19"/>
    <dbReference type="OrthoDB" id="7550572at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030574">
        <property type="term" value="P:collagen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201">
        <property type="entry name" value="MATRIX METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201:SF291">
        <property type="entry name" value="MATRIX METALLOPROTEINASE 1, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="767"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1012"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="10">
        <location>
            <begin position="856"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="binding site" description="in inhibited form" evidence="8">
        <location>
            <position position="844"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="913"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="923"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="925"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="930"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="935"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="942"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="946"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="949"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="969"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="977"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM91915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1081" mass="124770" checksum="828DA8D1691491D9" modified="2016-11-30" version="1">METINIPVEDLDPSFLPSAQDAIQTPIENFDRILSPFKNCFVHVSNFRGINLLPTDTPFILRQPELAIWDESKRKRRHLHNLILVPKGTKPRQNSSAIYGTPCELSDFFFGGDGTLSPCLMLKFSNFVSKSKTLNCQINIGIYPQEYHFLSTWDLKHPNGTYIQLGYLHSFGSPIPVNWEIYHMQPSAQPLNILIFEETYRKRNETELKSWLEDWMRRVNYGRCLITKDLFIFLETNERKPSANFSLRIVFASAVTIDLGPSDKSSYLNLRALENQFWNTTVEAMLSKIESYHAKPIVSWYHNDDNIDLEEDRSLNAQCSRNPYFIVWNYRQINSEIYNRKNEQRLLWDATVNILQLIFSNTSLIYNEYRAQFECVDINLRDSFGIIFSTQVEVALLRFDKTRYMNMPLTMKNPMRALKFISCGKPPQKTVGFEEFVIIYRWHVWLLIVVLIVGIFPVSFHFVEKLNLTIRAQHLRESLKQFSSNLFLQPIIILLEEGEAFVGNNLNLSSLQWMLGSLLIAGTVLSNAYKYDNVYNIIAPIKLLPYTHFRQLVSNNFTVHTMISVEGSDFNEFAWYLDNVTQINQHQIRGRFLLSNIQIESEVASLYLLDEFNTNVTGEYVTNSRLHPGILELFQKIQQENVTKNDRHKVFAGEQWKLVTDTVKVCNRSALILPELFALQLAQSMRKVDGLKYVFVGKDFLFAELISLEFRGWIPINIWAKIGSLESSGIWFWWENVIGSANGRVAEQEYVRAAEVAVEKPTMKGNVVVIFYLFCGVCGISIFSFVVESVENLQKQEWLKIDPNYENTDAQSLKFCVNDFRGVMGLEDRVKLNNSILTTIPILCGLEKEEKRYVITGSRWNSTSLSYRILSYPRRTAILGGQANIDKEFRKAFAVWENVTDFTFTKKNWGESDIKIRFLTGEHGDDDEFDAVEAHSFSPMFGNEIHFNDDREWNIGSFAGVDIFQTAGHYQRSDSIMYPNDVGYISNFSLHTDDVKAIQIIYGKKGKYSIPLWLAITWTALATVGIACMLLGVIVTVAVIFRYCKRKSGQRTALLEKSWLWDVEPEMDSEPTLEIDHSLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGH9</accession>
    <name>A0A1D2MGH9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14688</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001359">
        <property type="protein sequence ID" value="ODM91992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGH9"/>
    <dbReference type="STRING" id="48709.A0A1D2MGH9"/>
    <dbReference type="OMA" id="FNRCVDN"/>
    <dbReference type="OrthoDB" id="1551503at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="10">
        <location>
            <begin position="5"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM91992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="12253" checksum="F2793C5FFF7EB456" modified="2016-11-30" version="1">MDYSEARTLKDFLYLYNKISEDCFKKCVFNMTRRTLDDEEGSCISTCVQKHVKVNHKTMEFFAEINPIFQQKKMEEHQQELQKLQQQQQATATSAVADTTTESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGP8</accession>
    <name>A0A1D2MGP8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stabilizer of axonemal microtubules 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM154 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001315">
        <property type="protein sequence ID" value="ODM92159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGP8"/>
    <dbReference type="STRING" id="48709.A0A1D2MGP8"/>
    <dbReference type="OrthoDB" id="365640at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033336">
        <property type="entry name" value="SAXO1/2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05217">
        <property type="entry name" value="SAXO1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="22636" checksum="D53781CA6BEC1A2A" modified="2016-11-30" version="1">MVAPQCSPDLGFLQFSPTTAAPRSYASMGGGDCCPLPPVGCGSQVNFCGNHPRDDCCRIPQARCLPTLPCCTPAPVCVERVKNMKPDTIYEPPSVPFDGCSRYRIDYRGPCGAPAVSCKPTNTIDQSGSRMDGMSVYRDAYTWKPIGPIERPRMTNDYEPSTAPFEGCSSYRVDYRGCYGLPAQSVKAGDHCRSIIWQNGWLFQLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGV9</accession>
    <name>A0A1D2MGV9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Uridine kinase</fullName>
            <ecNumber evidence="8">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_14458</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01001293">
        <property type="protein sequence ID" value="ODM92219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGV9"/>
    <dbReference type="STRING" id="48709.A0A1D2MGV9"/>
    <dbReference type="OMA" id="IRVQDYN"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043771">
        <property type="term" value="F:cytidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000200">
        <property type="entry name" value="Uridine-cytidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="10">
        <location>
            <begin position="275"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="509"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM92219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="650" mass="72092" checksum="5B5927BDC214B401" modified="2016-11-30" version="1">MSKNIVKVFRVYINQQSNNHDALNRGNKKVEMELESNNNRNSLNITSSSAPSPSILKNPTIGMFGMGNSNSAGLDSGGKGSNNSVGGGKKLTKILIPKTVVVTKDPPSSASSERLEIGGYDQGYEFDAIIKTMVPGPPGSVETDEMTDENPLDSNVTTDTENETELMFNEDDDDVILLHEDEEQSSASSGSNDPTITKKKEIPVVVNRDQRAATVLSPEGGSARRRQRTLSSNGALLGSSSRRHDGILRTLTRTIYTAGRPPWYDAQGQHVEPCVIGICGGSASGKTTVADKIIQELNVPWVTRLSMDCFYKVFNAEERALAGRNEFNFDHPDAFDFDALLEVLHRLRDGKKAEVPVYNFVTHSREVNSKTMYGANVIIFEGIFTFHHLEVLNLLDVKVFVDTDADTRLARRLRRDISERGRDLDGCLKQYNKFVKPAFDNYIAPQMAHADIIVPRGGDNEVAINLIVQHVHSQLQARGLKVREKLAEGWCKELLQSATDPDSLFVLPTTNQILGLHTFIRCTHTPRDEFIFYSKRLIRLLIEYALSLLPFQDVVVDTPQNVLYKGKRAKVTKICGVSILRAGETMEQALNEVCKDIRIGKILIQTNTATGEPEVDPEINEKFHVMPGIGNFGDRYFGTEPCDDGLDEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGZ0</accession>
    <name>A0A1D2MGZ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein spinster 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_14545</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001322">
        <property type="protein sequence ID" value="ODM92134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGZ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MGZ0"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF96">
        <property type="entry name" value="LP14756P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="23"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM92134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="526" mass="57657" checksum="D86FADC47A95C949" modified="2016-11-30" version="1">MNNNEPDSVTFAEKWRGSWMLTVLGGIYLVGELGHYLIGVISRDVAEDLHFGDLGCFERPDVPGIHFGICENANTSDICTNITNEHGTFACEWQYTGLGLDYQLLAGPSFMAVFTVAGIFWGIAGDKTNRVYLLFAATLLFSISTACTGLCQKFWHVIVCRVVQGVGVAACSPLAAGMICDVFGQKRRGTAMSLYNCGMYIGYGLSYAVGTYVTQANLFNEGWRATFVISGIPGIVLAFLLLITVRDPEPKPTESPVEEKGAKEASYTYEAVHSYSAHPDGGTDDTESLISNHQEQTASQAGRMESDWRQCFRFVTLYLILAACLRRSAGYTLRYNSALYFQVYYPGLDVGWWLTAIYCIGGVLGSVLGGVTSDMLVNKLGVKARAVVLAVGQLVATPFSVLMFYMDPPYVFIPQTVGYLFGAMWFGAMFTILVEIIPSSIRSTAFGVAFFIMENFGGNFPVIVHHLSDILGYRLALVIMYPGELILSKIAYVQALSNNQHKQQDESASNDNVLCCLFLQVLSSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHW1</accession>
    <name>A0A1D2MHW1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein SET</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14083</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001193">
        <property type="protein sequence ID" value="ODM92598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHW1"/>
    <dbReference type="STRING" id="48709.A0A1D2MHW1"/>
    <dbReference type="OMA" id="VIMNHPH"/>
    <dbReference type="OrthoDB" id="19419at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="255"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="33936" checksum="DADBAD59D1169FA2" modified="2016-11-30" version="1">MNSSAFLSVPIFYQGVKMSKFQGPSPRKMMRREVEEIPSDSDSDDGLVDSDDGLDKETRDAIFELDKFQAEIADLDNKAAKEILEIEEKYNETRKPIYAKREVAIGKVPTFWSKVIMNHPHLNMIIDDEEEDVLSFLVKVEIQEEDNVEDGFCIKMGFNDNPYFENRELVKVFQLGGSLLDGFVEPTTSSTVIKWKEGKGQDLQKKLEEIIQKRKGEMTSFFDWFTGDKNPDDDQVADAFKDDLWPNPLIYFLHQGGMEEVEEEGEEEEVEEEEEDDSDGISNLGRNESVEEEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIH5</accession>
    <name>A0A1D2MIH5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Collagen type IV alpha-3-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001156">
        <property type="protein sequence ID" value="ODM92755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIH5"/>
    <dbReference type="STRING" id="48709.A0A1D2MIH5"/>
    <dbReference type="OrthoDB" id="2344588at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="15837" checksum="8F02DB20FB1389A6" modified="2016-11-30" version="1">MQLQILTDTTSLNHALTQSGLKIVDFRGEALTFKTCFMKFKFILGDNGCLINSVSSCTEFMTQREDLWKKKHEREVQKRKKLEENFNQALKRAQRKKAAMGGPDCEEGPHSTLNEDEFYDAVELGLDRLEEEAAFKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIR2</accession>
    <name>A0A1D2MIR2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">cAMP-specific 3',5'-cyclic phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001124">
        <property type="protein sequence ID" value="ODM92890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIR2"/>
    <dbReference type="STRING" id="48709.A0A1D2MIR2"/>
    <dbReference type="OMA" id="APECPGF"/>
    <dbReference type="OrthoDB" id="6111453at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40141:SF2">
        <property type="entry name" value="3',5'-CYCLIC-AMP PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40141">
        <property type="entry name" value="3',5'-CYCLIC-AMP PHOSPHODIESTERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="6690" checksum="10B966FAFCFE71E9" modified="2016-11-30" version="1">MLDFDVENGGAGRSPLEGGGTPSPGLVLQAQPPRRESFLYRSDSDFDMSPKSMSRNSSIASEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIS6</accession>
    <name>A0A1D2MIS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Growth/differentiation factor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_13860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TGF-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001139">
        <property type="protein sequence ID" value="ODM92821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIS6"/>
    <dbReference type="STRING" id="48709.A0A1D2MIS6"/>
    <dbReference type="OMA" id="FNHRINI"/>
    <dbReference type="OrthoDB" id="5948587at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.90.10:FF:000006">
        <property type="entry name" value="growth/differentiation factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001839">
        <property type="entry name" value="TGF-b_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015615">
        <property type="entry name" value="TGF-beta-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017948">
        <property type="entry name" value="TGFb_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11848:SF262">
        <property type="entry name" value="LD29161P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11848">
        <property type="entry name" value="TGF-BETA FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00019">
        <property type="entry name" value="TGF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00204">
        <property type="entry name" value="TGFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00250">
        <property type="entry name" value="TGF_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51362">
        <property type="entry name" value="TGF_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 8" id="KW-0339">Growth factor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="TGF-beta family profile" evidence="9">
        <location>
            <begin position="171"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM92821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="283" mass="31437" checksum="FD5F227B176F649F" modified="2016-11-30" version="1">MNQIVIGKQSKNVHHFTFSEKMSNMKIESATLYIYVRNTHHHGPADKKNSNFSIRIRELIQKKGESPVSVDIYGLFKPAGATSSLSHGRHNRSRWVQIDIRAALSKWVSASTSSRKITLVIEAVDNSGNPSKEVTVVNTSESDGHSSSSNADVNAQYPFIEVHVSESGRIRAPRNIGMTCDENSQETRCCKYPLTVDFEEFGWDWIIAPKQYYANYCSGECPFAFLQKYPHNHIVQQAVPSGVGGPCCAARKMSSISMLYFDGDSNIVYSVLPGMVVEKCGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJP0</accession>
    <name>A0A1D2MJP0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NADPH oxidase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_13668</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001098">
        <property type="protein sequence ID" value="ODM93014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJP0"/>
    <dbReference type="STRING" id="48709.A0A1D2MJP0"/>
    <dbReference type="OMA" id="WFVVPGC"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000056">
        <property type="entry name" value="NADPH oxidase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000012">
        <property type="entry name" value="NADPH oxidase, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF58">
        <property type="entry name" value="NADPH OXIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="462"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="619"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="129"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="203"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="315"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="658"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="788"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="796"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM93014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1088" mass="124887" checksum="0831CE65AE4D90E2" modified="2016-11-30" version="1" fragment="single">MSSDPIPGQTEMPFLKELDLVLANKSKLALVPREKSEDVSVKIENRQIPTYSQINQAQNQGSVVLNSCGSTTDLITLWQNRVRFNIPPENQVVMRRTSTKAFSRFSNAVSHLNFRQHPNKTQYELEGMEKEELFQILFHLFDRKQQGYLNQYQWIEFLKVRLIGIGPEKEEKWVEFVFLLESTAYSVCGDGNVDFENFCKIFGDKDVLSKFFRLIDEQGNGVASAEMVMEFISKLMNNHSSNQLNKENILTLEKLFRTVVGNGDFIRKEDFKQIIPTKNEFFVDRAFDIFNQSGSGFISLAEFLDAMHQFSSGENPDAKIRFLFKVYDADQDGVIKGEELETVIRACMSENGMKFSCTQTAQLTEALFEDAAVDGKGGITFEALKSQLEKHPENMSSMLDQWLVPLEKHKKRSCIKTPHQFTANYIKNNYVYLIWYYIFIITNIALFTTRFIHFHLENPDAIIYLVIARSAGQCLNFNCTFIVILMLRHCLTFLRSRGASFFLPIDQNIKFHKITGILTFFFGVLHTIMHLINIAEGIIRSTGSLGDCVAQNMSCPINSGNWSYSEFLFNPRVTSQSGVFSMGLIPGYAFNTGVVLIIILTIMAIGSSPCLRRGGSFQIFYWTHLLYYLFWTLLIIHAPQFWMWFVIPGTIFLIEQAFRYYNWKVGRGHTWVSSGILLPSKVTHVVIRRPPNFDFHPGDYVFVRIPNISKYEWHPFTISSAPEHQDAIWLHVRACGQWTTRLFQYFEAEQAIVFDSKKATDIQATSAAVNISNAEKLPIFMTPKSKLKSSQSFHTSGREPMRKREIDLESSPRSISAYELGNYKSKNRDESARRAAARSFKYVRNKPQIIAFQTPSEKQGESVEEEQNVNEIGSETQGGGIGMPLEIHLDGPYGAPSSHIFRAEHAILIATGIGVTPFASILQSIMHRYWASRNCCPNCNFKWCNELMRSVLNLKKVDFFWINRDQKCFEWFVQLLSQLEIEQAESGVMERFLDMHMYITSALQKTDMKAVGLQLALDLLHEKEKRDLITGLKTRTNAGRPNWNKIFQQISDQKKGKVTVFYCGPPALARTLKFKCDEFGFTFRKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMF3</accession>
    <name>A0A1D2MMF3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-phase kinase-associated protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000868">
        <property type="protein sequence ID" value="ODM94041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMF3"/>
    <dbReference type="STRING" id="48709.A0A1D2MMF3"/>
    <dbReference type="OrthoDB" id="2095648at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051341">
        <property type="entry name" value="Zyg-11_UBL_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12904">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12904:SF23">
        <property type="entry name" value="PROTEIN ZER-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="217"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="546" mass="61285" checksum="CAFDE43F14855897" modified="2016-11-30" version="1">MNPPPKTEFPSTSSSSTSSSVLLNTSGGAVKRDMTGFASLLNLKDGNCTATRARRIQISQMGASSRASSDGGLGPGLKKRWSFHSSNQINELLKEDRVMKPIISPKRRKPNSGTTLTRSNSETCKYSATLHPRGHRKLLDQSASSKLVLTNHQQLQSKPHQKTKVIAMSGECSTSDSKSRQRLMDEYYSFMDPYPASYYKFCVQPKPSKYSREPPPPDRISSMPDEVLLRICKFLPKPALSNLGRTSRRFSGLIEDDTLWKRLCVMNKILSPEHLIIISSRKPMYLRMARTTIPDPDVLPNDLTELTSSSQLRFLDLSSATISPFALSIIMKISPKLIKLSLEHLIVTKEVVQSMMGFVGSIEVLNLTMCYDVDAKTLMEFLSNCQVLKELNMSCLRCDWSKEDLTSIISKLPGTLQQLNISGYRNTLDDTHVAMIASRCPKLLELDVSDSQEMSGKSIEHILKLKNLQHLGLSRCYGVDPPYYSHLSCCKHLKYLDLFSLFKETSIRQLSSTLPGIEINKYLFSAVARPTVGNKRSSIWLQRVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN57</accession>
    <name>A0A1D2MN57_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L13a</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12208</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000801">
        <property type="protein sequence ID" value="ODM94477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN57"/>
    <dbReference type="STRING" id="48709.A0A1D2MN57"/>
    <dbReference type="OMA" id="GMLPWKT"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="203" mass="23205" checksum="85D247D9D0505BCB" modified="2016-11-30" version="1">MSGLSAKPIKIDGAGHMLGRLAATVAKTALQGNRVVVLRAELINMSGNFYRNKLKYLAFLRRRCNVNPARGPFHYRAPSEIFIRTVRGMIPHKTQRGKDALHRLKVFEGIPPPYDKKKRVVVPQAMRIMCLKPGRKYCYLGRLSTEVGWKYAGVVHQLENKRRMKNAIREKKRKIKRKITRTATDKIAKVAQPYNAVIKAYGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNB1</accession>
    <name>A0A1D2MNB1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000787">
        <property type="protein sequence ID" value="ODM94559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNB1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="41558" checksum="3EB103AF2A19BC61" modified="2016-11-30" version="1">MKRPELKIEPTKNTDTLVVHNDEQGKLANGEKSEKDNTATGTDPSNGESRARRRKRKKKKPRCQCECDPCKYLRKKICPYFPICCNLKLMTSVQILAVIDMYDPFIERIKGARSTNPFVSGAGAPPPSVKVTTPKYLDLFQESTTVLGPALFGSEVDADSEAIRYSKIAYLKRKFAQEVDRGCGSDYYVEHLFEHRLNVTRNLFYEVVKANYFVELLYVFNAVSILITTCCYFSYTSARTYLVVIWVLELVPIYFRLGLIIVSQSQRFCIFEYGLSRNGFKGLTVAFWLYLVPLIFYRPYKILVLSCFIYSLFTTAGNLQLRTKIEEMTLKQYVAMQEGYLRMDKDRDKSSSADEENETIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNN1</accession>
    <name>A0A1D2MNN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molybdenum cofactor sulfurase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000775">
        <property type="protein sequence ID" value="ODM94647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNN1"/>
    <dbReference type="STRING" id="48709.A0A1D2MNN1"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="410" mass="44050" checksum="CC6C654FE11931F2" modified="2016-11-30" version="1">MAKKNERGKEQRQGSNDHDYFDDDDKDDDSFALLPLVFLGIIEQYAFLNQKTVMLAAQLLRSRVVTASLSQTLLSLVNNLIERLRGNLVVGCPSLGDNETGFEEEEWSEVRIGDLLFKSGGPCTRCATICTDQNTGERSPEPLLTLSAMRNGRANFGIHLYNIPDNSPVQATTISASASLLPVDAQQSISPSWAEKVHIRTIKPWSGVDEPLQENGIATVPSGRYSAEKNKTPLEKLHGAFSETELQTSEAMMMEQAAAPKTVQNSGTKLKNRQLSSNSSSESFTLSKSSSTKLANSSISIANQVQAIHIGDPVSAQKNQRAVTGALASTMTKIHTGSSSSTNGQLHWSKNSATNSATTPIAGEKSNSSPSPNGGVKTSISKESFQISSPSDLGMEGNLAEMQSLIESID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNW8</accession>
    <name>A0A1D2MNW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000788">
        <property type="protein sequence ID" value="ODM94551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNW8"/>
    <dbReference type="STRING" id="48709.A0A1D2MNW8"/>
    <dbReference type="OMA" id="QETEDIC"/>
    <dbReference type="OrthoDB" id="510539at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="4">
        <location>
            <begin position="198"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="553"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="651" mass="73935" checksum="FDC4543FC1E974EF" modified="2016-11-30" version="1">MKRLLVDANQFAFRLDSRERSSYPILLDSDHPDELAHRFFGIPYYKGAALIRMMDGFLTSKTLRSGISRYLKRWAFKAAVQDNLFEALQEQAVEDGIELPNNLTVTDIMNGWTKQRGFPVIRVVTKNSSAISIIQVQNHVRILEQGKTKKLQEQALLSWHVPISIASADEPDFSNHLPKIWIPKDVALVNVDVDTSKWLVINPDATGYFRVHYDENIASLLREQLNTDHSVISPMTRSQLLDDYFNFATEGELQISKALEFTTYFGNETEEIVWHILLSNLRRLHYFYREYPDASSRNTSRSLPAFQGLRDYLLPRLEGALMKIGFEQSPEDRGIIITTRSRLLTWACRLGSQMCFDYANNLFVQWMNSPEKNPVPLDLQDFMYCYGVRAGGGRNWLFAVDQFAKATNLLQSLRLAKSLTCIEDEDVLNVFMDSVIDKETLGVSKEEFLVIFESLSSNPSRRHLAIKFLRTRLPAVIRYLNGTRSVNVLFSLLTDYLHTEEDLLEVQKIYSENLPQILMEKDVVDIDEHVTDIKDNIQWMAKYYQPMREWFDSQTREDKRKQQQQALAMPQDGQGSNQGASGGVSNFFNGFISGFTAALQGGVSGANSLFNGFGSAANNTFNGLLVGYNATSQGLVQGASNVIGDPNNRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP32</accession>
    <name>A0A1D2MP32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Activating transcription factor of chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_12059</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000782">
        <property type="protein sequence ID" value="ODM94614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP32"/>
    <dbReference type="STRING" id="48709.A0A1D2MP32"/>
    <dbReference type="OMA" id="WNEESVN"/>
    <dbReference type="OrthoDB" id="5847285at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14692">
        <property type="entry name" value="bZIP_ATF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="349"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="443" mass="48683" checksum="C75889A4EF88DB37" modified="2016-11-30" version="1">MSPPEQSHKPALSSVVTSRAQTASNVLNELERLHSFEHHNNDFGIAANEESVDLNMDLFEELADIEYTPSLLSSPEESKPFEVPSSQPLPAPVVVSTPQQPHLINVSSLAAAMTNNDTVKLSAEFKSIVESLTPSLATVPINNVIATNTFENLIQITGIPTTTVVGDECLVPVEFVGRASSISGTGDAETMDLDGIVISNEMEFINERDLFSLEELSAELVAEESNHSTTKGSVNNAMLVNGVLPQWAKGMTIPLDNLDYELSKNDETLNALLKGDVPAAKSCISSPAYVQEAFSPVSNFSSEDDETNMMEEDAAVEVIETTKPAAPVKQERRGRKPAKAYKDPLTYVRDKALRKKEQNKTAATRYRQKKKQELNVTLTEEEELQKVHDDLDKERESVAGELRIIRALLRQMLEVRRKKKTPSPSGVTASSLVQAQKVANRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPF3</accession>
    <name>A0A1D2MPF3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000734">
        <property type="protein sequence ID" value="ODM94903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPF3"/>
    <dbReference type="OrthoDB" id="6406818at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="19867" checksum="69E9EB3DABF7D305" modified="2016-11-30" version="1">MGGQSQLSSDSDVPLQSDFISSPGSSGEVNPEWDGVRPDKEADEEVLEDAPLSSGTMHFRYDEELSPDNGGVASRDRYEPLFFNRMVLPELVGQNAIRGKVANHLQYLANGRGGVKPVRRPLPLPQQVVREPVIWSSKSNYGIPAEGYIRANGYDKRSPRCIAKCMQQGMVHPLQCHSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ27</accession>
    <name>A0A1D2MQ27_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11479</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000697">
        <property type="protein sequence ID" value="ODM95209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ27"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ27"/>
    <dbReference type="OMA" id="MMIRSAT"/>
    <dbReference type="OrthoDB" id="185455at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="5">
        <location>
            <begin position="239"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="412" mass="46085" checksum="01363F2FE27EAF0A" modified="2016-11-30" version="1">MYQRKSLRSAGASSSAGGTQQSQNFPSTSAAASSQLNSQLNKQDDDHDSSENEDGEEYGDMHRLVLQGIMAAGYLDVKGVKKLFQESCKQLKCKVPAAEHLSPPFIQRVVREINERIKDYDMMIRSATCEVTGEKFYVFLVTIEKQVMKFQTYFTKAELDLFKKILDSLLRKHRYFSITETDCINIGGEIDPRSFSKSNAEDFVVKMISLQYFTKVCNNKDNEDDYEITLGFRTIREFEPIFREVYHDVFTNCCLCKMILLNGLQCPKCPAVIHRGCLKKYIKNCKTCVSCKGPWRTEGSLLIRARSTESDDDASPTTKPSESSGKAKKSRLAANGDEVDMPILEPMVSPRSAGTSASQSQKKASPSSKQKEKETTSSSTRSTANAASSDKKKTPAATRTRRARNRVSSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ63</accession>
    <name>A0A1D2MQ63_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000735">
        <property type="protein sequence ID" value="ODM94895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ63"/>
    <dbReference type="OrthoDB" id="6478931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="346" mass="38383" checksum="D01CA761905C360A" modified="2016-11-30" version="1">MSECESISSQCASKNCDEMETIIVEDLVKPVIFILNYAQPFADTIMYSSEARSFLAVKGSIWRKSFCILLELLILLRLGVKTAPIVSNYSNGNDNGMTALAKGAYFIFLSFYAVVKWTARASLIFVILYIVFTIIIYGVDSLKFTNYSDPNRNGSSKPSRFKLDFTEIHSPHDSTVSKIVFAVEIRTFNEIGKLIETFNQHYGLMNVLGLAVVVTYISTSVEHVFSGFQNIFKPGAGLHLFLSYIPMMIPALLLAEVSRVAGSFAGIIKNQFGKFTKECGDPAEALCGIAIVHYDLATSNIGIKGLGFYTVSYQFITTVLSLIVTYSIVIVQMFPHDESQENDLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRC8</accession>
    <name>A0A1D2MRC8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Estrogen sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000639">
        <property type="protein sequence ID" value="ODM95659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRC8"/>
    <dbReference type="STRING" id="48709.A0A1D2MRC8"/>
    <dbReference type="OMA" id="RDFKLNM"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="66"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="349" mass="41083" checksum="C29698B312249CBE" modified="2016-11-30" version="1">MADFDFSNPPIDFSELSDSSVGKKWEQHCHKVFYDEGWVRLGKIKACFARNYVRYYERIRDFQTQPDDIWVSSFPKCGTTWTQEMVYCIATDLDFEAAKIGLQKRFPYFELRANWSPNLTKIIADNVLKSNNNSSTEDENKSFFLNSFDLVDHLERPRFIKTHLHYSLLPTAMKNEQSPKMIYVARNPKDACISLYHHFCLMDGYGGSLEDFVDAFVQDTVFCGPYWTHVREYWEIRDRPNVLFIKYEDMKKDLPSVIRQTANFLGVTLTEEKVERLTEHLSFESMRKNPAVNYEDIVCNMRSLHGTFHESKFMRKGKVDSWKDEMTPEMVAKLDAWVAKNKIMGLYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRW1</accession>
    <name>A0A1D2MRW1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleolar MIF4G domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000614">
        <property type="protein sequence ID" value="ODM95839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRW1"/>
    <dbReference type="OrthoDB" id="10260961at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="7445" checksum="5DC953AA65F62DA1" modified="2016-11-30" version="1" fragment="single">DYLDAFEKLNHLDLRNNQDREIIHLALQYNLWDRLKDLNFEELDKSSKEKSRTTCCSFNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT25</accession>
    <name>A0A1D2MT25_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10512</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM161 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000569">
        <property type="protein sequence ID" value="ODM96166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT25"/>
    <dbReference type="STRING" id="48709.A0A1D2MT25"/>
    <dbReference type="OMA" id="RFALMPI"/>
    <dbReference type="OrthoDB" id="784140at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019395">
        <property type="entry name" value="Transmembrane_161A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13624:SF6">
        <property type="entry name" value="EMEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13624">
        <property type="entry name" value="RE42071P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10268">
        <property type="entry name" value="Tmemb_161AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM96166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="487" mass="54186" checksum="7A9C33120AF919EA" modified="2016-11-30" version="1">MALFGVQLAISVIVASIISKFGARLSLARYLLCNTGLIRFLHPTDEELRELAGVPKDVMGKGKGKGKNQDYKNPNTFHVPKDLDIKLDSVHVGPAEVIHLRYYTEYQSVLDYTIYATVVYFATEVYYSFLGPKDEMNLSIYWCILTLLWCIKVLLSVTKVYFRGDEVMGERALCMCMGGAYLLASMMFLIVDENTLEVGLDSAYDSFHLHASEFLKAQGLPSTGPASKLILKFVLAVFSAILGTLFTFPGLRMSKMFYDSIKYCEGRTLVKTLLNLAYVFPLILTILWIRPLGRDILAKPFAGSDKALMSEAAFESLRIILVVSMVVLRIAVMPFFLQSFLNVAQEKMIEQRKEAGRILNTDLQKKVAGIFYYLCIVAVQYVAPCLICLHSCFMYKTLGEGSWLGDLVAGNENASNGTTPAFKPVLPDTDEVLPAAQHFAIALASLKVVFNATVFRGIFGYMTWWCSFLLIASSGVGSLYLSYGTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTN1</accession>
    <name>A0A1D2MTN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000571">
        <property type="protein sequence ID" value="ODM96154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTN1"/>
    <dbReference type="STRING" id="48709.A0A1D2MTN1"/>
    <dbReference type="OMA" id="FTEGCAA"/>
    <dbReference type="OrthoDB" id="1545884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043193">
        <property type="entry name" value="GLOD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46466">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46466:SF1">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21701">
        <property type="entry name" value="GLOD4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="138"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="32957" checksum="FDC352BE75BD1F45" modified="2016-11-30" version="1">MSQRRALHYVMQIGKRKDAMGFFKNVLGMKVLRHEEFEKGCEAFCNGPYDGKWSKTMLGYGPEDNHFVLELTYNYGIGSYRKSNELRSIDILKKDLKPVLASGGIMERIKRDGLEMNACTVECEDYRVRVFENKAVNKIDRVVLATTNMTRTMEFWNGALGMSKDKDSCLSYSSEQCKLQFENHPLTEADRSQPFCRTAFSCPTEQLKGIEKLVSSRSDGSKVLVPFVTLPTPGKADVHVVVVQDPDGHEICFVGDKEYRQLSQVDPQSDKLLCFVQVGCMFAKKGGKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTS5</accession>
    <name>A0A1D2MTS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromodomain-helicase-DNA-binding protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000555">
        <property type="protein sequence ID" value="ODM96298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTS5"/>
    <dbReference type="STRING" id="48709.A0A1D2MTS5"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051493">
        <property type="entry name" value="CHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056342">
        <property type="entry name" value="HTH_CHD6-9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46850">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46850:SF1">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23078">
        <property type="entry name" value="HTH_CHD6-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromodomain-helicase-DNA-binding protein 6-9 tri-helical" evidence="3">
        <location>
            <begin position="199"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="313" mass="35980" checksum="BB5A32A58458E424" modified="2016-11-30" version="1" fragment="single">MEALSNKESSDETSKDIPTEPETPASDSLDKAEERDLEKTSDKGSEESENKITDEPETKEVPADDKVITKETDVENSKLKEILQPGGESKTPDETTTNITESDQLSSNAEGNVIIPTTNLLEASLNQPQSCAVEEPVIKMEEGIMQGCENQEQQSVNSKLEFPTVSDLNNRLRKLITSFQRNFKKEEIKNAQKAKRLERKEKIEQIVREREMQKLEMLQRRWSKKEENDFFKTISTFGVQRYKFSKCQNVTTRNQHCSSCLIMVLIGAGKYDWNKFRAISRLDKKFDDTLTEYFRAFYAMCKRVCGKKLSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVH0</accession>
    <name>A0A1D2MVH0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Condensin complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09592</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000474">
        <property type="protein sequence ID" value="ODM97090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVH0"/>
    <dbReference type="STRING" id="48709.A0A1D2MVH0"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="10">
        <location>
            <begin position="631"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="986"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="540"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1006" mass="114685" checksum="95C890706DC220CE" modified="2016-11-30" version="1">MSARSLNVSIDDARQREKYQTCVSKLAPIFDAIQTDDESSSKEAKKLKDKRMKQVDAVFEETGLKIFSETLIRMMIVPFSTKDSLYVTKVIQFFYDIVTDERWEVGDGSSPNDTVMSVTSNCSNMSVIEDGATEPLPVRILRLCERYHTETRALVRLRIMQTFDKIVPQRITPFEIRRGLQLRLTKMLLTRLRDKSDPVRAVAAVNLCAFLEEGLPYQGVVLDNLLTHMAFDPDPAVRAKIVSTIKITDETLEHVVERTGDPDNTVRTAAITRVTKDINLSSLTLEMREAILMANTTEENPKIVQKAVSLLLEHWLQCLKNDPCEFLRVLNVRKRHLLCKKVLDSVYNQPSEEAFEKMKEPLFKDKDKKYPDDSLSSENTFLWLYMYKRFKDDHYVFTKLALPVTEMIEYIKEYLEVVEDEGDLTNADLDYRSWMLGDLLLILQYLPCEEGGRQAVVQFVSTLFLNKKLMDVRNCVLGVKLISSCSNIQDETVVIDIVNSVLYTDRDSTRKSERRSLSSSGVSDSPTSLKIELGNLTHKRRKLEKDRDIAVRENDLYKAQACQDEINELETKIQNIKVRIDEASPDNSMTEETEEEEEEKWNYSDKTMLIAMSTVKTNILLSGRISTFSRTFYEMYVVKAVSKCSPVVRAIALEVMTLIAFEFEDEFPRASLFCLTALLKDQLIVKTQALKCLHDLIMRYSFARLAGWKLLLCKYLQLILGLSFFILGFYDNLLIYFCSYFCPETQEVKGILYGVNTIKDLPTFQTGGEDTTATLRSLLMSYIRHAEAKLVKVSVSGLLKLLFKHDLNTSRIITSFLMNWAIPTYELQLRFKEVSVMIPVYAMMGEDEAIEVAKCLFQCLKKIQAQIGSRGRDTPAKLPCSDASKIITLVVTCTDPSRLSKFQRPYIGHETIAITAVEELQNVELTSDEKTQYAKLLKSLNLSQCPKNSIKQLITSVSNIAESTNRTICGILNGFLQHLASLLPENESQMEDETQVAAGAFDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVH8</accession>
    <name>A0A1D2MVH8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000473">
        <property type="protein sequence ID" value="ODM97100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVH8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="89" mass="10065" checksum="9736F1DA7B46C720" modified="2016-11-30" version="1">MDQREARKYVSNNPPQDYSQSERRPSLLGRLLYRRTSSLSESENMAAGLQRRGSIEQPEAGSITQRVQTELVYNTGRRGSTAKEASIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWN0</accession>
    <name>A0A1D2MWN0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000449">
        <property type="protein sequence ID" value="ODM97372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWN0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904658" evidence="2">
        <location>
            <begin position="25"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="33289" checksum="154246B859E29602" modified="2016-11-30" version="1">MGGINRNPIIGIVVTILFIGMGNCADNISASKVSTETGENQRNSAGPALFKPIKPKTPDCSNYFPGTPAWNECFRVFTSEMANFNTRMQEHMQKYKQEDGANGASIVTQFGPGYYSESHQNSHSTSNNYIGGYAITAENLPISTSIVNGVLKVTLRTGQLDKFDSKIEGQEIKLNALSQGQSKAVRIAIPTGISINDVKIDRTPDAIYITAPVKLGNGGNSNFQWSSTSGNGASSSSSFHNTGGEFNTGGGGGMPPIPDYSNMFGNMFQNIFGLAFGGRNFGGRAMQPQMAGYNNNPFPSYYTPQVWFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXU6</accession>
    <name>A0A1D2MXU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000427">
        <property type="protein sequence ID" value="ODM97624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXU6"/>
    <dbReference type="STRING" id="48709.A0A1D2MXU6"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="32289" checksum="BA187FDCA8B5D389" modified="2016-11-30" version="1">MFFEYVPRIVNDDGKWVNMFLQIKEKGKRSDRPPFLDFSCLSSRSLQLLILSTAFTAFGSYSPLFHLGSTLVIGGALFALATLHGNHGLGSFCWIYGFGLGSYNYVLKAWTYEKTRAKNFSRAWSFVQCAQGLGCILGVPATGYVNYYAGLRSGYFMSSASVFFSAAIMFCCGMDRRRLMRNKSGTSSMKTCETFDSSGMQSPTVRRISFTFPDEQISPRLLSKGSSRSGSGVSGMDRQSFGGSIKSYNGNNNFGGTHHHHQPVLLDQPQNRIPKELTCISEEGAQEPHGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY62</accession>
    <name>A0A1D2MY62_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450 4c3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_09094</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000428">
        <property type="protein sequence ID" value="ODM97585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY62"/>
    <dbReference type="STRING" id="48709.A0A1D2MY62"/>
    <dbReference type="OMA" id="FGMRTVV"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF201">
        <property type="entry name" value="CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0349">Heme</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM97585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="242" mass="27174" checksum="190EC45E4AFCB8C9" modified="2016-11-30" version="1">MKGVDGIKGSGNSDFVSMIEVMLENGVTDKEIFEEVAITLAVAHDTTSVAMQIALFLLALHPDHQEICRAEADELFSDPTKYNDGNLQFSALPELKHLERCILESSRMLSLASILMRKLDAPLQLQEGLVIPAGVSIYVFPPVIHKNPEYFPNPEKFDPDRFLPEPSKQRHKYAFLSFAAGPRNCIGTKLAIIEIKMMIAKILHKFVVTTPDKYEDVVIIPSVIPGPEKPIRFIFKRRNDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYC3</accession>
    <name>A0A1D2MYC3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetratricopeptide repeat protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08644</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000387">
        <property type="protein sequence ID" value="ODM98039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYC3"/>
    <dbReference type="STRING" id="48709.A0A1D2MYC3"/>
    <dbReference type="OMA" id="MNANYIS"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039190">
        <property type="entry name" value="TTC14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184:SF9">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="161"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="344"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="378"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="705"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="805"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1088"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="528"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="596"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="616"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="632"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="706"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="853"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="878"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="925"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="946"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="975"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="987"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1012"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1088"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1107" mass="124441" checksum="71AB5AA929BCEBD2" modified="2016-11-30" version="1">MGDSEVRVPKGILKNKYGSNSSSRDSGEVMEVGRHSSMGYGSGSWETQVLGGSSNNPLPVPVPAPQHGMNMPNPVLASIDPISRGIGSEYLSLQQKLHEFIKSKRELLFRPLDDDETPLSDVKGTLRNSEDHYAIVPSLDHFLKVDTAEIKRYFYQNAQVGDIVIGRVISRSSSGVYLKLVCTEGGKHIVLEELGVKTFCPTQQSVQIVDPRDPNRYFEIDDLVRLEILEVNPDTEKIVSGMKGVTLSAETQHSFQLGLLSRHDLPRYYILSKYKHSGDFKSRRTYEEMLLESPGFQNPNSVSHLASSMGVYNNSNSLMKGFRTGFPAKEMASQLRRTQNAKWAHGHVAEGIKYFKLGKFTEAFQCLNNALNIDAENVEGLVARGALHAHNGHYDKAIDDFESALKFNPNHFNARKYLAETLVAYGRQQESQGKLEDAIASYSKSLVVRADHKEAKEALWSLHARTEKLDPSKMTGAAAAKAAELKAKLKTILQSELGLKMESKTSKEKKSKKDKRRKDSSASEDESSSSSSSDESSSDSSSSGSGYKKKSKKRKKKKSKKSKKSRRDSGGDRKREISLSPFSKRLAEPQGGGLSSGSAFTGLTDSTYAELQLGIPKHERDGDDSDTESKRSSKRSKDKKRSKKSKDKKKKRKHASSDSSSSDSDTSRSKKKSKKPAAAEPAPLQGILPDLGDLEAKLSAYYSKIEQGKIETKLPKRSPSREKSPEPIKKRPRELYDDIPPRIVENVPPPKMLEHEKQPEKSLPWSERKSSGKIDLQTDEYGNIMQSETLVRTVVNQIPEQKGKFEMKFKPMNSGAPENENGTGSSAPPPPDLGSKWRPLGAAVPQSEAVKNAFERESVHSDDDRKNDKDKSKEERNYRRRSRSSSRSPGARRRHRSRSFSSRSRSRSRSRSYSRSRSRSRSPSYRRDRDRRSYRRDGGGGGGYQRGRPAARFFRGYNYPRGGGGSRRPFNPRPSFRDRDRDYSNRSKFRNRFSHTPSRSRSRSRSRSRSITPKDRRRDSSRDRRSFTREDRSDKSVSLSQETHSSRMEADSVSQSQEEKPSPVDTEIQIGSLKTTSAADVEFLLDKRNAEKKEEMRKSNPEFFRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYY9</accession>
    <name>A0A1D2MYY9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000372">
        <property type="protein sequence ID" value="ODM98222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYY9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10134" checksum="1B518B68CB052A33" modified="2016-11-30" version="1">MHVDPVRGIIVSAICYLARKSEEAIFIPSTHVSVELSTLGMGLIISSVSDDVDEPEVLDKMMGLARPGCYEECAMEMVRQWYPDPLLNHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZS8</accession>
    <name>A0A1D2MZS8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000346">
        <property type="protein sequence ID" value="ODM98522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZS8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="33167" checksum="0D35D1D85AF7133B" modified="2016-11-30" version="1">MPMSPGTPAPPMGGCHGARSPQNLSHYNNCGQQNTSQLSPGTNHAHSPMSPLPPQHPQHAHLQQQNQVQPGANSPQNLAQYHNHHQQQKHQGMTQQQIMYQQMMNQRQQQQRAAHHNTQSVIQQRAMTPAPPMSPAPQPTHAHHNQNAAHAQMDSRMGMGYGHHNSMAQHGPTMTHPVPANSPYPAGYSRAMASTPGVQNPSTAALSSAAAAASQSRHNQQSHHHAQSVGANHNHVNSNSSATTGSKIANPAASSISKLQQMAHGLDRCQSIPPQLTPPPNNHQQTLTPPPGGPNMAMNNMVVVAAQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Q6</accession>
    <name>A0A1D2N0Q6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000348">
        <property type="protein sequence ID" value="ODM98495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0Q6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="19328" checksum="019744BB7C5D8ACE" modified="2016-11-30" version="1" fragment="single">AWRDEEWLPTRGEPSRNTRASEACSSTKQRRITRSMVIALEKGVTDRTAVANAQQNEDPKRKPVIKSTTATAKGLNPKRKRKAKHHPGLDLLHEQTYRSLAMPDQGPAPGTYDVILFDTRKAVALPGEIRHDPSHRVDMNFLLRTDFIEALDKEFHLKRVSKVGLVEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N171</accession>
    <name>A0A1D2N171_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmembrane emp24 domain-containing protein bai</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07886</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000321">
        <property type="protein sequence ID" value="ODM98804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N171"/>
    <dbReference type="STRING" id="48709.A0A1D2N171"/>
    <dbReference type="OMA" id="TKDFAFM"/>
    <dbReference type="OrthoDB" id="759142at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="36"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="24274" checksum="552556075DE32F45" modified="2016-11-30" version="1">MKLFEGSVSPSLVALIVTVLLSEVSSLMFHLQPSAQKCLREEIHKDVLVSGDYEITEVPGQTVDLAVVDSKGGFLWKKEHAEKGRFTFTTDEYEVYEICFTSKVPHGQRGFPQEVYLSTKHGVEAKSYEGLDEAAKLKPLEVELKRLEDLSEAIVKDFGFMRQREEEMRDTNESTNSRVLYFSIFSMLCLLGLATWQVLYLRQFFKSKKLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2N2</accession>
    <name>A0A1D2N2N2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sorting nexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in several stages of intracellular trafficking.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000274">
        <property type="protein sequence ID" value="ODM99519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2N2"/>
    <dbReference type="STRING" id="48709.A0A1D2N2N2"/>
    <dbReference type="OMA" id="HPVFRED"/>
    <dbReference type="OrthoDB" id="9976382at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090389">
        <property type="term" value="P:phagosome-lysosome fusion involved in apoptotic cell clearance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07621">
        <property type="entry name" value="BAR_SNX5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06892">
        <property type="entry name" value="PX_SNX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000008">
        <property type="entry name" value="Sorting nexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000001">
        <property type="entry name" value="Sorting nexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014637">
        <property type="entry name" value="SNX5/SNX6/SNX32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45850:SF1">
        <property type="entry name" value="SORTING NEXIN 6, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45850">
        <property type="entry name" value="SORTING NEXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036924">
        <property type="entry name" value="Snx5_Snx6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="35"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="323"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="418" mass="48235" checksum="99252382B86FBB27" modified="2016-11-30" version="1">MYIPLKTRHKPRCWGQVLSSGVFRSTKKPGRSDGELQENALAVEISDSLSEREKVKFTVITKTTLPGFEKSEFKVVRQHEEFVWLHDRFEENEEYAGYIIPPAPPRPDFDSSREKLQKLGEGEGNMTKEEFSKMKQELEAEYLATFKKTVAMHETFLGRFACHPIFRNDHNFRVFLSYDEELSVRGKNKKEFFGSLIKSFGQSTDEVLLSATQKDVDEFFDTQRNFLIDYHSNLKDATVKADKMTNLHKNVADSYIKISSELLQLATIDSNELEKFLTKVAEALEKARKVEYRVASDEDLKLSDTLRYYMKDSNAAKNLLYRRRRCLANYETANKNLDKARAKNREVGAAEQAQQEACDKFEAMSAKAKEELVDFKKRRVEAFKKNLIDLTELEIKHSKAQIQVLSTAVQSLKEELGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3H1</accession>
    <name>A0A1D2N3H1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gamma-interferon-inducible lysosomal thiol reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06852</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000253">
        <property type="protein sequence ID" value="ODM99827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3H1"/>
    <dbReference type="STRING" id="48709.A0A1D2N3H1"/>
    <dbReference type="OMA" id="VNNWENI"/>
    <dbReference type="OrthoDB" id="958254at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="27164" checksum="2C6E98BDF52BAB05" modified="2016-11-30" version="1">MTHFESHGVIFRLRFALTILGLVGVLLVQESSAFMGRRAHFRETISPRKEANNSVTINLYYESLCPDCVDFISRKLCPLWEDMSNYLRIDFVPYGNAETIVSKTGEISFECQHGPPECEANFIHDCALKHLSYKESIKFICCMESRHSAHGTAEICAEELEVDYAPIKTCAAGPEGIKLHYAYGQRTDKLVPSHEWVPWILFNGQYNKEDMDHAQDDLLSVLCKYIEDPKPTVCNEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N488</accession>
    <name>A0A1D2N488_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vesicle transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_06826</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000251">
        <property type="protein sequence ID" value="ODM99864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N488"/>
    <dbReference type="STRING" id="48709.A0A1D2N488"/>
    <dbReference type="OMA" id="ISCCDTE"/>
    <dbReference type="OrthoDB" id="73614at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF6">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="17841" checksum="F646D3533715B917" modified="2016-11-30" version="1">MDKLRRALSGEDRESQAEQGGFNEIIDSSSLSWSTRIKGFIACFLLGFIFSIFGSILFFFHNVKGFGICYSFGSIVSLLSTMFLMGPIKQMRKMFEGTRVIATAVMLGSLVLTLFFALKVGNGGLVLLFVIIQFLAMTWYSLSYIPYARDAVKKCFSGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N490</accession>
    <name>A0A1D2N490_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000257">
        <property type="protein sequence ID" value="ODM99745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N490"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="150" mass="17160" checksum="8B943E772976E71B" modified="2016-11-30" version="1">MDRETLLVKRLSKIDIFITIVNFGFGMFFVSSLWNVSGLRGPVEVFSLPTYYCYYMSAVALSTYVSFTSVYFYHSADEEPFPEIVKYYTKLTSICSALVVCVTAWLVSTKIVENPFEISFKWGLIVLLIMYRGLASWHHVRTLEVATASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4M2</accession>
    <name>A0A1D2N4M2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000249">
        <property type="protein sequence ID" value="ODM99885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4M2"/>
    <dbReference type="OMA" id="FAVCIMI"/>
    <dbReference type="OrthoDB" id="8296878at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905026" evidence="1">
        <location>
            <begin position="26"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="36695" checksum="C4971521D487592A" modified="2016-11-30" version="1">MWAFNMEFIWKAILFQILICPGILSEDISDPDFIAKYDETIKKVACEAIGQKDGAQMKINLDRYSTREEMAKLAFWNFGNDFTKTKLEFGEDIKWKRDLVDTMFNIFTLSCPNDSVPHGYMNLFRELGMIYLNSAEPRTTENAGAWAHIQRVLKACEEDLTPYEVVSSMLHITGLRGDKGNFTETTLILPPEEKVDATFPQLDLVVENLWFVFSHGMGRCYHKLPETAILAPKLRALFIRDILRALLNKWGDPGPVQDFGPVVGNFDINRVQRNIRHCVTISYFINGINEFQMVRPLKVGHVNEGINSVQNRKTGATIHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N578</accession>
    <name>A0A1D2N578_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein msta, isoform B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000207">
        <property type="protein sequence ID" value="ODN00429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N578"/>
    <dbReference type="STRING" id="48709.A0A1D2N578"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="400" mass="45601" checksum="1CD5A0737AABC4CE" modified="2016-11-30" version="1">MRCKGKTTSVYHMASMLTSNCIPNASWVIQDTLDFYLRASAPIKTGERITISFVDPLLGTWDRRKQLWQEKYLSCTCSRCSDPTELSTFFSAIKCPGEGKTGGESIGVNCECEGYLLPTDPLAAVTYSWNEEGGENDDHPPQEKLCEERMAEWKCNVCLMRQPWGFIQNSLQKLKTQRDDDICPGNDGASSNTNADKPQANNREGWRDHKNYSRLQLLQTRVDQITRLVGSVAHMNHYLILKMENEILTSISQLLEEGQVPLEDMEKWAVRMVELCKKGLKVVNVLCPGLSKARGRLLYYLQQGLMINLLFKTSRAMRITHSDSEECSPPKDSPSHEELTKKFQELLLARKEILEIFAIERGNSAESGMLRAVQHDSIEMRVLKNHFKCHQNISSWNFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5H8</accession>
    <name>A0A1D2N5H8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000202">
        <property type="protein sequence ID" value="ODN00517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5H8"/>
    <dbReference type="STRING" id="48709.A0A1D2N5H8"/>
    <dbReference type="OMA" id="HEFGKHD"/>
    <dbReference type="OrthoDB" id="72976at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019396">
        <property type="entry name" value="TM_Fragile-X-F-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13568">
        <property type="entry name" value="FAM11A, B PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13568:SF6">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 185A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10269">
        <property type="entry name" value="Tmemb_185A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="358" mass="41375" checksum="6875CBF1EB84CCC7" modified="2016-11-30" version="1" fragment="single">NTVRFRSRMNVERISQDFNPSKFVVYSCLFVFTILIALRQDETITWSYWAVFTPIWLWKLMVVLGAVVGSLVWWRHPHYRMEGEAYIQYKAMMMTLALHLLLLMFELLVCDNLESQRHLWILVFIPLIFISIISIAICIWAVKNDRSFDLELFCSVNILQFIFLALRLDNFISWDWEVVFVPLWILLCVSLVGVLYSIIFAGIIFRAPEVNAEQRRSSTSSAIGYTFLVIPILIFQVLLTNKLDENMNISYMAAVSPLCLTYIQLILTSFSNKRSNKWWFGIRKNFCHFLLDVCPCFQEYCNISYSVQDDEDEGRGGRDAIDASGSEFQASSKSTPAIVVSKINSKPIVPIVSIEMPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5P4</accession>
    <name>A0A1D2N5P4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_06079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000197">
        <property type="protein sequence ID" value="ODN00600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5P4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="7143" checksum="C900DCB249C09E71" modified="2016-11-30" version="1" fragment="single">TLDILLLLREVKRKPNNLKSLPSAVKLVQRSNATVTRVASFHATRAAHKVVQRWLDTRPESPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5Y4</accession>
    <name>A0A1D2N5Y4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta,beta-carotene 9',10'-oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000193">
        <property type="protein sequence ID" value="ODN00667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5Y4"/>
    <dbReference type="STRING" id="48709.A0A1D2N5Y4"/>
    <dbReference type="OMA" id="PEMSDNH"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003834">
        <property type="term" value="F:beta-carotene 15,15'-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="525" mass="59465" checksum="67EA925DDA0BAEC2" modified="2016-11-30" version="1">MPQRDLRRLYNNSGESKKPEEVFIEGKVPEWLNGTYLKVGPGKYHFDEFSMRHFIDGYSSVAKFEIKNGSKVIFQKKYLETDVLKRANAAQKPVVCEYGTPPQQDPNKGFLSRCIPTLIPEMSDNHNMAMYNLGTNLCVAGESCFFREFDYKTLQLGTKFDTNKCYGLNFTCPHPITDETGTTYTIGSSFITGLKYNFVKIPPMTGKPSTKEVLKKAKIFATISSQVTSMLSMHHSFGITKNYVVFIEQPYVLNVTKILGGVLTKGQCFFDWLEWRPELRNKFYLIEKETGKVLKTEVVSQEPFMFLHMSNCYEEDNQVVVDLVRFDNGDFFDANFIQKILSDRHQMESEFASVERFVIPLVDNVSSLQEGKELVSLGYTTASAVRKGKQIILSPEIFSKKGLELPFVNKTFLGKKYRYVYATGNTAPPGFYENTLVKIDLETKITKTWQGGPCSFPGEPYFIPNPNANEDDEDAGVVMCAVLDTGKDSNDHLLFLDAKTFQVIGKATFKDNIPFVIHGTFIPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N681</accession>
    <name>A0A1D2N681_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Sulfide:quinone oxidoreductase, mitochondrial</fullName>
            <ecNumber evidence="14">1.8.5.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Sulfide quinone oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_05917</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro). It is believed the in vivo electron acceptor is glutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a quinone + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + a quinol</text>
            <dbReference type="Rhea" id="RHEA:55156"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58905"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.8.5.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:55157"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ubiquinone-10 + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + ubiquinol-10</text>
            <dbReference type="Rhea" id="RHEA:62608"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:46245"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58905"/>
            <dbReference type="ChEBI" id="CHEBI:64183"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:62609"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ubiquinone-10 + hydrogen sulfide + sulfite + 2 H(+) = ubiquinol-10 + thiosulfate</text>
            <dbReference type="Rhea" id="RHEA:38359"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="ChEBI" id="CHEBI:46245"/>
            <dbReference type="ChEBI" id="CHEBI:64183"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:38360"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SQRD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.8" evidence="14"/>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N681"/>
    <dbReference type="STRING" id="48709.A0A1D2N681"/>
    <dbReference type="OMA" id="ERYSMFI"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106436">
        <property type="term" value="F:glutathione-dependent sulfide quinone oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070224">
        <property type="term" value="F:sulfide:quinone oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070221">
        <property type="term" value="P:sulfide oxidation, using sulfide:quinone oxidoreductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000034">
        <property type="entry name" value="sulfide:quinone oxidoreductase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015904">
        <property type="entry name" value="Sulphide_quinone_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632:SF2">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="17">
        <location>
            <begin position="40"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00052986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00060891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00066447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00070160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00082958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN00778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="50279" checksum="138ECC949621D5FE" modified="2016-11-30" version="1">MSYRKLLLSDIHSLSRRSESVWTWGTRKFSSTRSNGNRHYKLVIIGGGSGGCSISAKFAKTMGSKSIAVIEPSDVHYYQPMWTLVGGGMKSLADSGRPMSSVLPSNIDWVKDKATEIKPSKQTVVIGTGSSKQEIQYDYLVIAVGIQLQYEKIKGLPEAFNSAGVCSNYSSLYVNKTLQALKDFKKGNAVFTFPNTPVKCAGAPQKILYIADQYLRKNGKRDNAKLIYNTSLGVLFGVKHYADSLWNVVKSRDISVNLRRNLVEVIAKDKAAIFEDLDNPGKFETVPYEMLHVTPPMGAYDLIKSNSEDIPDAAGFVDVNKGTLQHVRHPNVFAIGDCANLPTAKTAAAVAAENGVLFRNLTNFMNGKEPEFIYDGYTSCPLVTGYEKCILAEFDYNGQPLETFPIDQSKERRSMFLMKKDVMPEIYWKLMLKGNWNGPGTFRKLFAPFKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N684</accession>
    <name>A0A1D2N684_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc transporter ZIP14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N684"/>
    <dbReference type="STRING" id="48709.A0A1D2N684"/>
    <dbReference type="OMA" id="ITMFAGE"/>
    <dbReference type="OrthoDB" id="200954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140410">
        <property type="term" value="F:monoatomic cation:bicarbonate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071578">
        <property type="term" value="P:zinc ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050799">
        <property type="entry name" value="ZIP_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12191">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12191:SF37">
        <property type="entry name" value="ZINC TRANSPORTER FOI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="40095" checksum="FA14846EE01F28E9" modified="2016-11-30" version="1">MEGLWGYGFLLVTIISCSSLVGVSLMPFMAKDFYKHLLTVMIGLAVGSLTGSAVFHLLPQALRLAEHDPDHEYLNISLYIVGGIWLFFMVERILKFIMDYKERKGKSWKREKMSSVLSSTPETSTIAVMTENGNLMKGPLVEANGGGGEQRNSLIFPSTPRDTGVIYECQEQAIKASFGHQEKPRLSSCHDHPVTFEQGKDSVIATVAWMIIFGDGLHNFIDGLSIGAAFNESIWTGVSISLAVLCEELPHELGDFAVLLNAGMSMRQAVTYNFLSACTCYIGMAVGILLGEIEASIYIFALAGGMFLYISLVDMVPEMNEIAQETSKVSVRKGIITLFLQNMGLFAGITALYLLAKYQDRFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7F8</accession>
    <name>A0A1D2N7F8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinol dehydrogenase 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000168">
        <property type="protein sequence ID" value="ODN01181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7F8"/>
    <dbReference type="STRING" id="48709.A0A1D2N7F8"/>
    <dbReference type="OMA" id="NCKRITK"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="712" mass="78820" checksum="5B4316565E4CCE50" modified="2016-11-30" version="1">MTFDITSSILTNYKITSSFAIASNPSSYYRLIKTSNNQVVKMAMSQAALVADYMGSITKHWFGFWKVNAEKVCDDEEDIKGKILAKRGAVVIMAVRDLEKGQVALDDIKKTLSPLEVQLELMKLDLGDLQSIKDFVKDFESKYSHLNILVNNAGFMDTNGKLLKTKDGFEQHVGVNHLGPFLLTRLLINSLKKGAPSRLVCVSSSNVAIATLDLDDLMMEKKVKTGDHGMEPYSISKLTNAICIKKFAETLEPDSGIKVIQLCPGFVKSDVFRNVKGVMNKIRNAVSLAFVGLTPHQGSETAVYCCVSKSVVAEPNEGKGDFYRFLKRWERGDKLLADYVKSEQGETLYRLSEEWIGLRDKNSRFKMPRSPFSRGMNYISDKTGHRFWSENATKVCDDEDDITGKIVIITGSNSGVGKEVAFQLAKRGAVVIMGVRDVQKGKLAVEDIKKSFPSSTIDLMTIDLGDLNSIKSFVAEFQSKYSHLDILVNNAGIMIVTKRSVTKDGFEENMAVNHFGTFLLTKLLLSSLTKGAPSRVVTLASTNLAIASLDLEDLMMEKRRKTGDNGREQYNSSKLAIAVCTRKLVSSLDPNCGIKFFLMCPGYVKTALFRDNGCCRKCLTNFGLCLGGINAHKGSETAVYLCLSKSVASGENSGKAEVYRFMKLWQFGENVLKEWDGTEQVEKLYAMTENLLGLHDTKSIAISKSVVVEAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7Q8</accession>
    <name>A0A1D2N7Q8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000161">
        <property type="protein sequence ID" value="ODN01294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7Q8"/>
    <dbReference type="OrthoDB" id="8189408at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN01294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="355" mass="40701" checksum="45E2E42A8CDB6385" modified="2016-11-30" version="1">MGRKIQKVKPAEQKIEWVFKINFDLNLTNEQARIAFLSGVERSYYPEDPGFSKFGLVYQLNLEGDVPPCNYTPPSFALTKPVSKKGYSIDGLSAPRFPKVNKHLDYPPPDKYQAELTDALLNSSRKPIPPAEDFFRLPPTDPFVLKHKEVLANQRTRQCYVGFGSLKTMPRFGKTPTFNSAGVGSYNLMPKQPPRPHLNSSFGRSPMICHPSTEIRCTYLTAEKCIECGKDLEICDHYRTRFSVRVPLPETRNPLDVGNDFPRGVRHVNLCNVCFYRAIQGHSKNWPKNKVRWLFKKVRTCANIHEHHNLPEIIHRADCKTVRKLQRKEAILSKYYADRVEESLPAKVTTVNDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8U2</accession>
    <name>A0A1D2N8U2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_05044</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000145">
        <property type="protein sequence ID" value="ODN01657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8U2"/>
    <dbReference type="STRING" id="48709.A0A1D2N8U2"/>
    <dbReference type="OMA" id="PHIATQF"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000173">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000043">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="50"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="16">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="187"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="158"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN01657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="30859" checksum="EBF25571004DC1D7" modified="2016-11-30" version="1" fragment="single">MVEMFVLPHIATQFQPSQRIYSSCLNSISASCLDVVKEERSGERQSLVLDAGLQFPVGRIHRFLRKGNAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGADSTHLFTRINLVVIMPKKRIAEATDSQKSTQHLKETQRTVAKKKAKASKAVKSGSKPKTKKRSKKESYSYFIYKVLKQVHPDTGISSKGMAIMNSFVNDRLAGEASRLVKYGKSKTLSSRDIQTATRLLLPGELAKHAVSEGTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9D8</accession>
    <name>A0A1D2N9D8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Glucosylceramidase</fullName>
            <ecNumber evidence="5 12">3.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_04826</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a beta-D-glucosyl-(1&lt;-&gt;1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose</text>
            <dbReference type="Rhea" id="RHEA:13269"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:22801"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="EC" id="3.2.1.45"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:13270"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a beta-D-glucosylceramide + H2O = an N-acyl-sphingoid base + D-glucose</text>
            <dbReference type="Rhea" id="RHEA:81447"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83264"/>
            <dbReference type="ChEBI" id="CHEBI:83273"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:81448"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine + H2O = an N-acyl-15-methylhexadecasphing-4-enine + D-glucose</text>
            <dbReference type="Rhea" id="RHEA:34755"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:70815"/>
            <dbReference type="ChEBI" id="CHEBI:70846"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:34756"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.45" evidence="5 12"/>
    <dbReference type="EMBL" id="LJIJ01000136">
        <property type="protein sequence ID" value="ODN01861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9D8"/>
    <dbReference type="STRING" id="48709.A0A1D2N9D8"/>
    <dbReference type="OMA" id="GPIMEEG"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007040">
        <property type="term" value="P:lysosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016241">
        <property type="term" value="P:regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051246">
        <property type="term" value="P:regulation of protein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032006">
        <property type="term" value="P:regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000030">
        <property type="entry name" value="Lysosomal acid glucosylceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00843">
        <property type="entry name" value="GLHYDRLASE30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8 12" id="KW-0746">Sphingolipid metabolism</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905249" description="Glucosylceramidase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 TIM-barrel" evidence="14">
        <location>
            <begin position="103"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="15">
        <location>
            <begin position="459"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN01861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="526" mass="60142" checksum="CD700CC97BC1FA65" modified="2016-11-30" version="1">MKAFILTVAIIATYFANQSQSATPCEARRFNHDSVVCVCTENYCDTLDPITRTDAGLVKVYESDRAGKRLEVREVRFGNDLPGVDPGRFKNVRVNRDRKFQEIIGFGTSFTDASALSLGRLSADLQTKVMKSYYSNEGIEYSLSRVVISGSDFSNRPYSYDDTPNDWSLNSWRLVDEDINFKIPQMHEAQRQRGSPIKFIGSSWSPPAWMKTNGEINHGGTLIGNTGSDEWKTYARYLRKFFEAYRENGLDFWGMTVQNEPMTGWDPWFPWNTCGFNAEMERDFVKNDLGPIMEEGGFGPDRFNIMVLDHNRPLAEDWANVVFSDNDATKYVKGLAVHWYFYGTAGPYDVYDRIHDKFPNQFILATEACNRNEDDENDRKGLGKWVLAEDYAHDILLDLLHYVTGWTDWNMVLDMNGGPNWVGNNHSAPIIVNPDEREFYKNVQYYAMAHFSKFLPPTSSRIETVPGVEEEGLLELGAFERPDGGTAVIIVNTKDNEEYFNVEDPALGSVKVKVEPHSFNSWVYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9Z5</accession>
    <name>A0A1D2N9Z5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000126">
        <property type="protein sequence ID" value="ODN02072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9Z5"/>
    <dbReference type="STRING" id="48709.A0A1D2N9Z5"/>
    <dbReference type="OrthoDB" id="152385at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="86" mass="9695" checksum="C9777FDC8A52E88D" modified="2016-11-30" version="1">MHAYPQFIYRFIEQTLQPGPAVSLKCSARGNPTPQVAWMLDGFPLPQSDRLVGRLIIRIFSASFVLLYATAYLTVFAQFVCSFHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAP7</accession>
    <name>A0A1D2NAP7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000116">
        <property type="protein sequence ID" value="ODN02328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAP7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="27440" checksum="EBF4D2DE18B69885" modified="2016-11-30" version="1">MEPGSASSGDMVIPFPAGWWKREEEPRLEPNMNLEPDNPITEGQKHSIQKEAVQASKPKLERKNPRSFRKYRWSNGLDLSFLETTRESEPVSLKPSFENKSTFIVEQKNEERANGIQEGEHVRQEKSEVDVGDGKGGSVTTGNELEAITKDWTKYYWGLRNDNAYVYPWMKPEFPVTEKMNELQIDKGTDKVQEKSIGSEDVVDAYAPVACDLDEMDSAEYWRSYRLYWERQPFFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAR9</accession>
    <name>A0A1D2NAR9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malate dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_04342</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000115">
        <property type="protein sequence ID" value="ODN02348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAR9"/>
    <dbReference type="STRING" id="48709.A0A1D2NAR9"/>
    <dbReference type="OMA" id="HTWVNGT"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01336">
        <property type="entry name" value="MDH_cytoplasmic_cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000010">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000002">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01517">
        <property type="entry name" value="Malate_dehydrog_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011274">
        <property type="entry name" value="Malate_DH_NAD-dep_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01758">
        <property type="entry name" value="MDH_euk_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003916">
        <property type="entry name" value="PRK05442.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="156"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN02348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="332" mass="35792" checksum="8725F20836FD86E3" modified="2016-11-30" version="1">MLEPIKVVVTGAAGQIAYSLLYQIGKGDVFGQDQPIIMHLLDIPAMMGVLEGVVMEMMDCALPLVRGIVPTADPAVGFGDVEAAFLVGAMPRKEGMERKDLLAANVKIFKVQGQALDKYAKKTVKVLVVGNPANTNALICAKYAPSIPKENFTAMTRLDQNRAQAQIAARLGVGIESVRNVLIWGNHSSTQYPDARHALVKKGAEEVKVTDALPDTAWLQDQFVTTVQKRGAAVIAARKMSSAMSAAKAAGDHMRDWWLGTSDGSFVSMGVISDGSYNAPSDVVFSFPVSIKNKQWTIVQGLAIDDFSRGKIEQTGQELVEERQEALAVCED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBS1</accession>
    <name>A0A1D2NBS1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Hemicentin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_03983</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000098">
        <property type="protein sequence ID" value="ODN02698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NBS1"/>
    <dbReference type="OMA" id="FLQIVAW"/>
    <dbReference type="OrthoDB" id="5969272at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20958">
        <property type="entry name" value="IgI_5_Dscam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000017">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000230">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000308">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000324">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013151">
        <property type="entry name" value="Immunoglobulin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF14">
        <property type="entry name" value="CELL ADHESION MOLECULE DSCAM2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00047">
        <property type="entry name" value="ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="18"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="15"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="624"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="721"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="804"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="902"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1004"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1225"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1323"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1421"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1519"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1617"/>
            <end position="1708"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1713"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1810"/>
            <end position="1906"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="1909"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="2008"/>
            <end position="2100"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="2105"/>
            <end position="2212"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="2217"/>
            <end position="2310"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="2315"/>
            <end position="2418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2425" mass="264775" checksum="79C242022457924D" modified="2016-11-30" version="1">MPRANTQGGDEESGPVFVKEPPSKVDFSNSTGAEIPCQARGTPQPEIIWLRADGTAVGDVPGLRQVLASGALVFPPFRAEDYRQEVHAQTYICLARNSVGTIHSRDVHVRAVVSQSYTANVWEEHVIRGNSALVKCNLPAFVGDFVSVSSWYQDDSQIEKNDVYVVNQPYSAKVFEEDVIRGNAAIFKCSTPTFVVVNQPYSANVFQEDVIRGNAAIFKCSTPTFVGDFLNVDSWFQDDKYEVDPIKEHAIKGNNAIVKCQVPSYVADFLTRNVIQIIIRTTLYIFPVVSQQFMIEVHNEHVIRGNSVTLRCNIPAFVADFLSVTSWGNSGILKCEMPSFVADFLQIVAWVDESENSYVYSSKANHVVAQHYASEIVSEYVIRGNNAVLKCNIPAFVADFVYNTYGDQEDIIRGNSAILKCKIPSFVSDFLSVVAWHDDIGNVYSPENVFVVTQAYDTYGDQEHIIRGNSAILKCRIPSFVADFLEITAWVDDEGSEYIIRGNSGVLKCKIPSFVADYLEVVSWHDSDDNVYSQDARNYVVAQQYESEPENEYVIRGNNLILKCKIPSFVADFLQIVAWVDSDGQEYTPQTTAALDGKFVVLPSGELHIKDVRPEDEPLGSSAPKFPTESRMQTLQKQSGSSVAVVCPAQAHPYPNFRWYKFTDGSTREPVELNERVKQLGGTLIIREAKVVDSGKYLCKQLCRLRKRRDCFDCYCSIGCPVEPAVQTMDFGRPATFTCHYQGSPVKNVTWMKDGKRLQTTESVIRIDAVRREDKGMYQCFVRNDQDSAQSTSELKLGGRFDPPRLTFKFREEILQPGPTVSLKCKATGNPSPEIVWELDSKKVTNGERVSVGQYATATGEVVSHLNITNVHSNDGGLYKCTAISKVGNTYHTARLNVHGLPHVKPMEKAQVVAGETFQITCPVAGYPIDAVVWEKDNRVLPINRRQAVFPNGTLIIENVQRASDQGTYTCVARNAQGYTSRGNLEVQVMVKYKMVNWVWVVPPVIVPFSFGDEQDTVDAGASVQASCMVSFGDTPLTITWSFHGAESSTASQKGVTTTKIGSRISVLVIESVDFNHNGLYTCTAKNAAGSTDYMAKLIVNGKEITFPVFVGFHGVAGFSVFIIAPKIVPFSFGDEPLLWGTSAQSSCYIVEGDLPLQISWTFHGSDVTTHTQKGIQTSKFGQRSSIILIDPIRLTSKASALISLILILCTTHAMFEDVRHVIPPNIVPFAFGSETIEAGEMAQLQCIVSSGDAPIHITWSFHGKDSSTTKQTGVSTMKIGERSSLLIIDSVNSDLVGTYTCFARNAAGNTTYSTELKVNVSPRILPFSFGDKDEPLLWGTQAQATCYVAEGDTPLQISWAFHGSDISAQAQKGIQTTKFGQRSSIILIDPVEFSANFTCSAKNAAGTANYTAELIVQIPPSIMPFQFGGDSLEAGQMGQLNCIVISGDTPLHFTWSFHGKDSSTSKQSGVSTMKLGERSSMLMIDAVNSDHAGTYTCFVRNAAGNASYSAELRVNVLPNIVPFTFGSDTIEAGEMAQLQCMVSSGDAPLQITWSFHGKDTSTMTQKGVSTAKFGERSSLLVIDSVSSHHVGTYTCFARNAAGNSSHSTDLRVNVAPRIIPFTFGDEPLQAGEFKSLDCTIAEGDLPLSITWIFHGQQLSSQMGINTVRIGKRTNLLTIDAVAASHMGNYTCSASNSVASTNYTAQLTVHVPPKIVPFGGDEPSSFGDAVQLTCLVATGDLPLQLTWSFHGSGDSKQKQEGVSIMKIGTKSSLLIIESLQATHNGQYTCRASNNAGTDEYTATVVVNVPPKIMPFTFGEGESALNEGEVAQVQCFVSVGEVPLQITWSFHSSQDDKPQDGVTIMKLGPRSSVLMIDYVKASHAGSYSCRASNLAGTDEYTTTLVVNVPPRIVPFSFGEEPLEAGSHTTLTCTADMGDLPLKISWIFQGQESREVTAQMGIETQKFGKRTNMLSIENVAQFHMGNFTCVVTNVAGSTSHSAELIVQVPPRIVPFSFGDGDDPLEAGTHTSLQCLVDQGDTPLSISWVFHGQNYHPDGVETTKIGKETTCYLLKHCPPFHAGNYTCVSSNKAGQTNYTAVLVVQVPPHIVPFSFGEDDEPLQAGFHTSLQCFVDHGDTPLTISWIFHGKELSSQMGVETTKIGKRINLLQIEALLLSMLGQHMNLIIHSILELGYYTCVASNKAGQTNYTAVLVVQVPPRIVPFAFGDGDDPLEAGAHTSLQCFVDQGDSPLTISWIFHGKELSSQMGVETTKIGKRINLLQVESIAPFHAGNYTCVASNKAGQANYTAVLVVQVPPHILPFSFGEDYEPLQAGSHTSLQCLVDQGDTPLTISWVFHGQELSSQMGVETVKLGKRTTYCSIEALLTTYESNHMCYSVIEGNYTCVASNKAGQTNYTAVLVVQGTVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBS9</accession>
    <name>A0A1D2NBS9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ecotropic viral integration site 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000098">
        <property type="protein sequence ID" value="ODN02708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBS9"/>
    <dbReference type="STRING" id="48709.A0A1D2NBS9"/>
    <dbReference type="OMA" id="LWGHIVA"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000002">
        <property type="entry name" value="Ecotropic viral integration site 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000003">
        <property type="entry name" value="Ecotropic viral integration site 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF22">
        <property type="entry name" value="RAB-GAP TBC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="5">
        <location>
            <begin position="81"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="638"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="685"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="534"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="651"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="687"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="732" mass="83701" checksum="64FD246A534470B8" modified="2016-11-30" version="1">MYRLIESDSKSCNSLPGAANNSTHSRKSSDTSELSLGHSSDKGSEQETEEDLWITWGRIVNEWETYWKKKNQFVRDLVKRGIPHHFRGIVWQLLCLAHDSPDKAKYADYIKATSACEKVIRRDIARTYPEHDFFKEKDGLGQESLFNVMKAYSLHDREVGYCQGSAFIVGLLLMQMPEEEAFAVLVKLMQDYRLREMFKPSMAELGLCMYQLEMCVQEQYPELHVHFTSQGFHTSMYASSWFLTIFTTSLPLAVASRIMDVFLMDGIEVVFRIALAILSMAKHELLSLDMEGMLKRLRTENKLLKHRIEVLESESSELANKLIQGQVGRAEEVETTFALKRELAAVRQHYLEAMKQLENVTQNYQHLLLVLDETNSTKQTSMDEISLKSELLKQKEELIQCLQNELVEVRLQEAENAVIMSDLRSRIQELEEEKKNLRMSAVDNSVAHLQEELIAVKLREAEASLSLKDLRQKVADLTTQWQKHLQEQEDNNADKKGTGTPLGNLFTSSRMDVQRLEEEVMSLKLREMHTIIELKEHRLKIMELETQVQVTTNQLKRQEDESRRLKEELETSYAQNKDYQSKLKDERRRYSDLESKLKEDSVHARIKDAEKSQRMFDLSQIISSLQLKNQELMAEKEMMSARCVSSSSESNGDKLDSESETTERIKELQDTIATLTIQLESLKEQKAAAAEASLSPAGNGSNSTTITTNGSSSKEVSSSPIAPAVNGVESEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBY9</accession>
    <name>A0A1D2NBY9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_03918</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="19">Component of the oligosaccharyltransferase (OST) complex. There are 2 OST complexes, OST-A and OST-B, which contain STT3A or STT3B as catalytic subunit, respectively. OST-A and OST-B contain common core subunits RPN1, RPN2, OST48, OST4, DAD1 and TMEM258, and OST-A contains DC2/OSTC and KRTCAP2/KCP2 specific accessory subunits. OST-A complex assembly occurs through the formation of 3 subcomplexes. Subcomplex 1 contains RPN1 and TMEM258, subcomplex 2 contains the OST-A-specific subunits STT3A, DC2/OSTC, and KCP2 as well as the core subunit OST4, and subcomplex 3 contains RPN2, DAD1, and OST48. The OST-A complex can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBY9"/>
    <dbReference type="STRING" id="48709.A0A1D2NBY9"/>
    <dbReference type="OMA" id="TWYAIGT"/>
    <dbReference type="OrthoDB" id="10261066at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043687">
        <property type="term" value="P:post-translational protein modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12610:FF:000002">
        <property type="entry name" value="dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF43">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 23" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="21">
        <location>
            <begin position="22"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="22">
        <location>
            <begin position="529"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00040922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00062993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODN02774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="710" mass="80373" checksum="2EA1A608B63F8BB6" modified="2016-11-30" version="1">MAVKLLKSKSGDATAQKYETLLKLSILSLGAILSFSTRLFSVLRYESVIHEFDPYFNYRTTKYLTEEGYYSFHNWFDDRAWYPMGRIIGGTIYPGLMITSALLHNFLNFFNFAIDIRNVCVFLAPLFSSFTTIVTYLLTKELKDEGAGLTAAVMIAIVPGYISRSVAGSYDNEGIAIFCMLLTYYTWIKAVKSGSVAWAAVCSLSYFYMVSSWGGYVFLINLIPLHVFTLMITGRFSHRIYVAYSTVYCIGTILSMQIPFVGFQPVQSSEHMLALGVFGLSQIIGFIDYLKSKMSKENFDVLFHALFTLVGVTVVAVGSILMITGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTAWSSFYFDLQLLVFLFPVGLYCCFSNLNDSNIFIILYGMTSIYFAGVMVRLMLVLAPVMCVLGGIAVSSLLGRFMKDIDQGGKGQDKRPVKPKEQAAQGRRNEISLAFVGMLTFFLVMYAFHCTWVTSEAYSSPSIVLSARSYDGSLIIFDDFREAYYWLRMNTPPDAKIMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASPEDKAYEIMRELDVDYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDRGSHIKEQDYYSPGGEFRIDREGSPTMLNCLMYKLCYYRFGSMYTEGGKPTGYDRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLPNRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC56</accession>
    <name>A0A1D2NC56_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patched domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000105">
        <property type="protein sequence ID" value="ODN02586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC56"/>
    <dbReference type="STRING" id="48709.A0A1D2NC56"/>
    <dbReference type="OMA" id="WVTDEII"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051697">
        <property type="entry name" value="Patched_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796:SF130">
        <property type="entry name" value="PATCHED DOMAIN-CONTAINING PROTEIN 3-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796">
        <property type="entry name" value="PATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="500"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="815"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="842"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="873"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="905"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="934"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="4">
        <location>
            <begin position="393"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1024" mass="115642" checksum="6FCD80B575BAB533" modified="2016-11-30" version="1" fragment="single">GLNFNVNSRSMSQKQGTASNDDASAAGIEISPEKRSNSRVDTTNPPSESKDRMTILQLISLKIVGSLERFFYRWGYQIGLTPVPFIVACVILTVLCGIGLLRFTPENRPDKLWIPWNSEFVKDTEWLNKNFPSPFRFHYAIITAEDVLQPKVLDVLLEIHNKVKEIEASTYKWKDICFKLPVIKFDTNKRRKREVNNANNSATLFNGNFDGFDSAFDFDDDEEATSEKPFDPSVSLPTDVYCNIVSSLDKECFELNMLELWNYNSSVINKLTKEEIVNAINHEQIRQVFYPVFGRPVNYATELGKLQRNESGYIIGAEAVMIRWFARLNRTAMNLGDVLNDEGTGQAVDKYNFMWEKELSKFFLSFRPPEGVNIYFNVARSFADISGSTIMGDASMLAVGFSIVFLYVIFMLGKFNFVEQRPLLSLAGLSCVGLAILVSYGICSAFKIIYGPVHNILPFLLLGIGIDDMFVIMQCWNNLRPEDMKKSIPEKLGLTLQHAGVSITITSLTDFFAFAIGGTTVLPALQSFCVYAALGIVATYIFQATFFVAWLAIDQKRIERRRNAFIPYIIHASFSPKTLMTRSFAQTAIEKIYCKVLFRKFSKVMVFLVTFGVFGVNVWGNILLRQEFNPIWFLPQDSYLFKYFAARDQFFPEKGEEGFILMNDVDLNSNLPKLESLLLDFENSTFVHEIDAWYPPFKQYVNSNFGKDIPNQKLTNKEFNKYLGKFLFSPTGGKYQSRFKFDKNLTCGKSAPAVMLSSANFKFNIFSGPEQHVPAMNNIKRIIREANFTPANSHTFIWSFAFAGWETDEIITDELYRNMGLAMICVFLTTLVLIANLQTCCMVLLCVILTLVDVGGSMHFWNLTIDTVSCIDLVLAIGLCVDYAAHIAHAFMTSVGTRNERSTKALVNIGPAVLNGGFSTFLAFILLANSKSHVFLTFFKIFFLVVVYGLFHGLVFLPVLLSIIGPAPYATAVLEDENNDKRETRELQVLLLVNQNNEPLGKPCCNGNTEGENVLLRNGKGDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NED4</accession>
    <name>A0A1D2NED4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NED4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37534" checksum="C2B0AF6C27A2CECC" modified="2016-11-30" version="1">MLGLIIIIHVHPLQAYELIFIVGSTAFVSFLQSLTFAVVSNILWTYSVVQTSMLYAEYFILGKLHAGKIRSVYIGIDFLVIITSLILLGAHIRWLMPSNFLPTLLMGTNKGRVSKWMKFILNPLQYISFLTCIHLMTLSILRSIINVILVVVYEMWKGSLKEIMSNLDFNQVMLNEATSTTKLTVLAFTSHVILQWAPVSTPIFLAFAWILTTFIVVLGVYYDMRFYPQNSNIGIKTTRLLTNLLIFSVSWLIALHLFPYLGILSMDDEDQVPSISTSELSKNILSINTGPFPSFMILLAHLLTTLALMTIMKVGVIMADIAFNIVILILNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFL3</accession>
    <name>A0A1D2NFL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Modifier of mdg4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFL3"/>
    <dbReference type="STRING" id="48709.A0A1D2NFL3"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="572"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="621" mass="68628" checksum="F4DC0021C731C95F" modified="2016-11-30" version="1">MWETPSKGHVVVVVANMTPQTLKNVLQYLYLGEVILDKKDINHFMDAADSLNICGVLANLYSCDISSTETTEDQRKQFETESDASETRNVSETAAARGISEYEDSEFRGSHSSGLEDTPKTPVIKYQGIKSRWRRRYSNTSFHGTPSKNSSDTCEQKRSASAGEVDLAPETTDERTNAGSMLEKSQAVVPEQNTTQVPSVVDLTIPDDEDRFEEDRSGTVESPHSKHRKIIQRAYPKDYSTSFDDSSDTNLEDWRTQSLFQSGFNPLTAPASTAVRPTRSLPYTIGSKDFSHPLQVSVDSQSPYGTNSPTSSTLEQSKAKSHSGFFPSSHSLPFQRTMHNSEPHSSTFTAAQPPLSLFSSHSREDRGLKYRLSAGLSPSVPSSSTYHRRQEFPSRSNYSLPPTETWSFSDTRSPSQFDETSREPIIEGRFRSDSMSLERSLSSYGSSKTYMPQTSHAMRLGDFAAQSHSFASGSELPTGSMSQHFSGSFLPQLRSPSSSTASTRPKTKAIRSSQVPQSSRYTAAEVDQMVDAVANYPGNIVPCTLCQKFVKRERLRAHIHECHLLSGEKIICPHCGIALKSKGSFRVHIWRHKRGALPTRNSMTDFGKGPPPSSASGPASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGG7</accession>
    <name>A0A1D2NGG7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric-chelate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGG7"/>
    <dbReference type="STRING" id="48709.A0A1D2NGG7"/>
    <dbReference type="OrthoDB" id="8295787at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905525" evidence="2">
        <location>
            <begin position="28"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="614"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="655"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="724"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="778" mass="87952" checksum="CFCC9EFD99317BCE" modified="2016-11-30" version="1">MEDGYKLVVVLNFLLFLLFRQSQYAAGAHTSLCIRLPKESFPDSTYKPSGLPPMSVGMEKFPQNIWKKYYYALHGDGSDPGYKHPELNYAFAFKGAQQFDINLHPVLGRIEPLVGWYGVELIFKANGPFDEIVRSFILMATDEQYNPIGEFVTTEDMAGSVGATCAANDATKYMIIPCGGVSKYEPTVSNVIVWASRTINTYDNQYGEHGPIVPAYKEKTLTFYYRFSMQDGNRNWQKYIVFRLLADLNEDYDWFNKEQTISDGEEKGLFSSISWFSLRTGHVPGATDPLLTNTESRDCTLPLIRQRPDQVNTRQWFIQRFSNEISADKREYQHSREHWVDHVLKYTGCSSAQFYGGRCVHTQCESNNNPRDMRPNPSGEIPRWHSTKTTNCPTCAGPDAFPWDCVVDVADEPKKYNNEDTTFPECLDGYSLTFSKSGCTTNLTKEDVRKIVITVLRKARGNETIITPGVTVTVNDTLKRINTRGVRGVGFGTLLYALRKGHGVLMVVVAMFFVPVICFTSRYFKETFMDSRILLARIWFQLHIQSVFWIVAFYLGGMLLAFAGRALLGVSLTIAGLSHRVLGWMTIVLFIILAVSGPIRLIDDPGRSCTIGTHWVLGYLFYFLNIVSIISSVHIPGCPISDHDESIIRDRDEFTVYKAFVILTLWMVIELVLGVIMTIHIHSHDHDMMVEGPRKYFPGFIGAAIPVLRENSHVDAAGFTCRHLIFYVYIGLALLAAILMSGSMIANKMTPFKGYGPMWCTHDEDTLSLLSGIRPECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-07-24" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHG6</accession>
    <name>A0A1D2NHG6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Anaphase-promoting complex subunit 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000041">
        <property type="protein sequence ID" value="ODN04535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHG6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008401">
        <property type="entry name" value="Apc13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05839">
        <property type="entry name" value="Apc13p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="71" mass="8007" checksum="2B810C45DE99AB9C" modified="2016-11-30" version="1">MDSQVNLDWYRANLIDNRWRQDSLPPGEAEVPPGDLPDPMDCADQGPSLTPKQMEQKWTDSGLARLLNLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHH9</accession>
    <name>A0A1D2NHH9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHH9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031462">
        <property type="term" value="C:Cul2-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042476">
        <property type="entry name" value="APPBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46575">
        <property type="entry name" value="AMYLOID PROTEIN-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46575:SF1">
        <property type="entry name" value="AMYLOID PROTEIN-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="154" mass="17317" checksum="5BFCBC0883D43C45" modified="2016-11-30" version="1" fragment="single">MAQDQDQKAGMADVTLYSLCLGPVSQRCSQIQMEHDLIPGNVLIDIFTMIAEDGNEIELAMLKSEMSKVQVLMKLMQVKLKRDKLHKIFKTMINRDITQAISNMISPICVPTVCRNIVESLVPARLAENFEEKCLVAIKSEGPHENLLKMGMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIA3</accession>
    <name>A0A1D2NIA3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutaredoxin-related protein 5, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Monothiol glutaredoxin-5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01691</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIA3"/>
    <dbReference type="STRING" id="48709.A0A1D2NIA3"/>
    <dbReference type="OMA" id="VKEYSSW"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="8">
        <location>
            <begin position="80"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="20114" checksum="9A5F2E6785536D2F" modified="2016-11-30" version="1">MNSFSRSCRLLIAKSRSVSTVPALSTFSSFTQFIIPSNRVSQRTTGYVNPVFQYGLAKFSSDAAPLSKEHIEKLVKNNKVVVFMKGVPDEPRCGFSNAVVQVLRMHGVTSYDSHDVLQDENIRQGIKDYTNWPTIPQVFINGEFVGGCDILIEMHKNGELVEQLSKVGIKSALLDEAKKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIE3</accession>
    <name>A0A1D2NIE3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Troponin T</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the troponin T family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN05021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIE3"/>
    <dbReference type="STRING" id="48709.A0A1D2NIE3"/>
    <dbReference type="OMA" id="CLSIRIK"/>
    <dbReference type="OrthoDB" id="330499at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005861">
        <property type="term" value="C:troponin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005523">
        <property type="term" value="F:tropomyosin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006936">
        <property type="term" value="P:muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006937">
        <property type="term" value="P:regulation of muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027707">
        <property type="entry name" value="TNNT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001978">
        <property type="entry name" value="Troponin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038077">
        <property type="entry name" value="Troponin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11521">
        <property type="entry name" value="TROPONIN T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11521:SF1">
        <property type="entry name" value="TROPONIN T, SKELETAL MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00992">
        <property type="entry name" value="Troponin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90250">
        <property type="entry name" value="Troponin coil-coiled subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="43165" checksum="DC42245FD6D99B91" modified="2016-11-30" version="1">MSELDEQLNVYIDEWRKQKSKEEDELKALKERQVKRRALRGQQEIALNERKKREEMERQKAIEEVKKKEAEEKRKKVEEAEKLRQLILKAEQEKRRRLEDERKKRAHEEQLKRLREAESRKQQGGRQGYGSSAQGSEGAAEALSKTKEQLAEEKAICLSIRIKPLNLEEINGREGLKRKADTMWTQIVTLETERYDLEERNKRQDYDLKELKERQKQQLRQKALKLGLNPEALTGKYPPKIRLASKFERRVDTRSYEERRGLFEGGYGKIIKEANEKLWQDRMDEFKKRPKTRLPKWFGERPGKKKNDPPTPEEEEGAAAAGGEEEAEAFIPEPEPEPEPEPEEVEEEEEEEEEEEEEEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJD1</accession>
    <name>A0A1D2NJD1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Solute carrier family 35 member F5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJD1"/>
    <dbReference type="STRING" id="48709.A0A1D2NJD1"/>
    <dbReference type="OMA" id="NMCITLV"/>
    <dbReference type="OrthoDB" id="10041630at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="548"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="583"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="53"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="648"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="654"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN05339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="682" mass="75253" checksum="4EE611ED52893181" modified="2016-11-30" version="1">MGRKISYACAFGDYEDVMMMWKARVKLAKHLVLDRLGKFSSNVRRSSGFSGVAMMSESSSSSSSNNDNHNHLNVGATSGSSSGGSSSSTSRVLLHRHDTNHSSQLHNSVGKPSAGDGGSFRTSLNDIDDDVLDSPVIGGSFIGGNSLGAINSGDDDHLFVGGGGGSSSSGQNERMRGQNEQPVSKSTIRLVLGIVVLVIVDVIWVASSELSSYLFHDEKFDKPFYSTYIKTSMFLIFLFGFIFWSPWYEQCQKGGDGYAYTLLAAEANCLATNTSIEDTVDDNANEAVLSAPAFVPINYDTAGSGNESDDSAHQRSVRFSKLAEVRHLSDHEAAEAFYSRLSYQASLQAEQIAFRLANRLSPSQTAHLAITFCLMWFVANYTYQLAVSHTQVGIVNVLSSSSSLFTLLMAAVFPSIASDKFSGSKFLSVLVSICGVAVVSLSDLRIETSNLPLGAIFALVSAFFYAAYLVFLRKKVDHEEKLDIPLFFGFVGLFNLLLLWPLFFVLNYTGIESFEWPTKRQWVVLVVNGIIGTVFSEVLFFSSIQINLGCFLTSSLIATLAISLTIPMSMVADVIFKKVSYSWLFYIGSVPVFFSFFAVTMFTHYENWDPVGSFWKRIWKQCWPSSSRSTTRYQRVLVNDMLDHNEQQERLLEDAEEEEDEEQERDEESGFGNENIGINSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKA6</accession>
    <name>A0A1D2NKA6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKA6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905668" evidence="2">
        <location>
            <begin position="24"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="176" mass="18957" checksum="056D6B2B3E16596B" modified="2016-11-30" version="1">MSPSGIVWSLLLLSLTLVQMGQCKTVQNTVPSIHGQERRIDNFVEFTDEGDQLAVESTLKGDKSDGKREILDKTGSSGRDCANVQKAILPIIPVIIASVIGLVGSIIIAIIVKTIISFFTQSQDSDGYGQDSGGGWSSSGSGLGFGRRKGFSLFGLENIDYPKLIKRVFTAIEKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL39</accession>
    <name>A0A1D2NL39_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 12">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="2 12">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_00658</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="2 12"/>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL39"/>
    <dbReference type="STRING" id="48709.A0A1D2NL39"/>
    <dbReference type="OMA" id="YSYFDRY"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05572">
        <property type="entry name" value="STKc_cGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000072">
        <property type="entry name" value="cGMP-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002374">
        <property type="entry name" value="cGMP_dep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035014">
        <property type="entry name" value="STKc_cGK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF144">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000559">
        <property type="entry name" value="cGMP-dep_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0140">cGMP</keyword>
    <keyword evidence="9 12" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 12 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="121"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="239"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="457"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="19">
        <location>
            <begin position="739"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="64"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="581"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="463"/>
            <end position="471"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN05961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="789" mass="88919" checksum="1B457F1DC2919BE8" modified="2016-11-30" version="1">MSDISDSSPEERPPGNGENIFSELNRLREALIEKEKEINRLQREVHKLKSVIEKSELTRIPSYKEGSHQKKCGVSGECGIVPDSQTKDGASDSAKPTPPDRHNKDFRTRQLIRAALGDNDFLQNLDTDQVRDIVDFMYPQKFNPGEYVIREGDQGCHLYVTAEGQLQVSQDSRNLGILKPGVAFGELALLYNCKRTASVRAITECKTWVLERRAFQMVMVKAGMQRIKDRMTFLKSVPLLKGLDTASLARIADCLEVELYPPGAFIIREGMCGDTFFIISQGRVRVTVSELAVRGADIVEGDEPTEEPKEPSSSSSDQIAPNGAKMLALRELSHGDYFGEHALLREERRSANVIAITNVEVLTLDRESFMQLIGDLSEFNRLKKPLHFSSCSQLPLQASSSSHMTGMNQILDDDDGEGAASSTEKLSKSLPNPSFEMFHYERKEDEFDHSHLKLDDLEFVATLGVGGFGRVDLVKVSFDPTKVFALKCLPKLHIISTQQQDHVYAEKNIMLSCNSPFIARLYRTFKDAKYVYMLMEACLGGEVWSVLRDKGSFDDAISRFIAGCVLQALEYLHEREIVYRDLKPENLMFANNGYIKLVDFGFSKVVKAGQRTWTFCGTPEYCSPEIILNRGHDKLTDLWSCGILLFELLTGYLRYDYITTLLPYSPPYGPHSENALGNDSSSDPLATYNCILKGIDSVKFPKTCSKAAVSLIRRLCRQTPGERLGARNLRDIISHRWFQGFDWDGLRSRKLKPPIIPNLRGPLDTSNFDKFEIEIEDTPDDLSGWDEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLI7</accession>
    <name>A0A1D2NLI7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLI7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="240" mass="25819" checksum="63471D30C3838537" modified="2016-11-30" version="1" fragment="single">MWNHAQNCSPSGEETNSEVDSSSNLKEKIERSLDLTHYLKYLDQLFSQEDNSESEYSDSDEDGKPRSFNEFLQPNAQPSDRPQPQYSQNHITVGISNTSDSNQSATYSTAKLVENFQLEANISSSSLSSIDSGTSSLSLTPSSDNCPDQHIKIERDNYGPSRSPVSLDKNPSVIDDEKSSENASENDKKPQKKKKANKSNNESFTRHHKPSSGGKGNGSSGGGAGGLSTNGGSGESSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLZ3</accession>
    <name>A0A1D2NLZ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Macrophage colony-stimulating factor 1 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_00531</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLZ3"/>
    <dbReference type="STRING" id="48709.A0A1D2NLZ3"/>
    <dbReference type="OMA" id="QIACEMI"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051130">
        <property type="term" value="P:positive regulation of cellular component organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001512">
        <property type="entry name" value="Receptor tyrosine-protein kinase erbB-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF600">
        <property type="entry name" value="PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000615">
        <property type="entry name" value="TyrPK_CSF1-R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 22" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="583"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="21">
        <location>
            <begin position="471"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="666"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="832"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16 18">
        <location>
            <position position="695"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="836"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="837"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="850"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODN06115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1037" mass="116993" checksum="548C9B07701E2042" modified="2016-11-30" version="1">MSICFLYNSLTLNAGAVTIPKIRIEDLDPRWMNISNGSNNTVLYSPAGGDIFAFCEAPYPIQWNISGIIAPAEVVKIQPPKRDWHDRMKMFQIQVNIFFGDATDFPDLTASAQIACEMITDYTMRDHFSIFVRGKNLFVNPSIKPLINSKLIPCPTTDPTIPTMLYLRSSDGVETLVQDVIYSPTEGFHSNQVFSGFFICRKQTSHVFFRARVTTPVQGPESDRQFSPLASNVKAFTDETIELACSSKTIPVVLVFSDATNATLTYTVDTERMKIAKLSLPKNSKQIFVQGKVACVSASFTELIKEWSFEFIEVPELYLDNFEGEVDCLSDLTPKRVQTVRCRNGMDCNFMDHCFQNVTHCNFKKQKQFVADADTSCWIEKLLDGKNCSSVPYSHYNGRVQCTVLGDFETVNISNPYSESPRKIDEFNVLGVLDINLPLDAVGMHCIAPWWNSTDIMITSRKFETRELLSPQMLLNEGNKIQKENFYIGQTNSRLACFAKGEPQPEYQWLVKTDDSSDFRNVSDVFPSLATSVGANGAGYLEFSNPDEKNSGQFKCVAKNRVGSVSRSYQLEVSPEPLSRKTAAYIGTVVAILFVLAIVIAALIIFIRRYNEAKELVRSLTDSEIEEFFQGRPDLLASVDSNFEVINFMPYKTEFEIPIEDIAFDSSEANLLGSGEFAYVVRGMIISKSKSAAVKISKPSADVTLFKSLLSEVKIMLYIGQHENVVTLVGVCTQDIRNRALYIVTEICELGSLDSYLRKRRKPFVNLINSNQEIERFVLHLGGVNFVCVRTFRSLLPEDREVKLSTLDLISFSAQIAKGMEYLASKSVIHADLATRNVLLTSEKVAKISDFGLSKKLYECNNYTKKSKTPLPWRWMSLESLNTLTFSTQSDVWSYGVTLFEIYTLGDIPFPNEDWDKQFLMRLASGMRMGRPTFSTQEIYSKIVACWESDPDLRPCFTTLRSFFEKMLKDLQYDPSLVNKEDTTKPLYSNIEDSTNNWAQNNSSNEPLYANTVAGEEGKPSIPSSCVKREKTNWGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMH0</accession>
    <name>A0A1D2NMH0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00235</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMH0"/>
    <dbReference type="STRING" id="48709.A0A1D2NMH0"/>
    <dbReference type="OMA" id="VPFHRVM"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01928">
        <property type="entry name" value="Cyclophilin_PPIL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000012">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF2">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN06470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="17974" checksum="03CD6BAE988ABBEE" modified="2016-11-30" version="1" fragment="single">SVTLKTDVGDIKIELHCEHCPKTCENFLALCASGYYENCIFHRNIKGFMVQTGDPTGTGKGGTSIWGKKFPDEFKDELKHNQRGVVSMANSNQVNTNGSQFFISYAAQPHLDLKYTIFGRVIDGFDALDELEKLPVDKKGRPLTDARINSVIIHANPIANSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2L3</accession>
    <name>A0A1D2M2L3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cystathionine beta-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005905">
        <property type="protein sequence ID" value="ODM87205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2L3"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17411" checksum="E20AC79DADD6B45C" modified="2016-11-30" version="1">MKNVVEDEEVSGYGDNMKWMQVSDAEAYDMTRRLIREEGLTVGPVSGGVMAAAIKAAVENGLNENPHAKILVVLPDSLANSSHISPPVDHDCSPTTPVKKCSESFEDTADFINYKGEQIESHHLSEYGVAMSDGIPSIVWARKFCQNFQTQVITRLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3N0</accession>
    <name>A0A1D2M3N0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative histone H2B type 2-C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005093">
        <property type="protein sequence ID" value="ODM87542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3N0"/>
    <dbReference type="STRING" id="48709.A0A1D2M3N0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="21955" checksum="72A5A2A8E2EA990F" modified="2016-11-30" version="1" fragment="single">QPQQQHTTHSLSRLTESSIFYSHQVNQTRSQHATKGQWKGCKKAGKAQKNISKGDGKKRKHKRKESYAIYIYKVLKAGSPRHWSLLQSHVHHELLCQRHFRSVLLLRLPVLLTTTRGPPSPLGKSKLQCVSFFPESWPNTPSLKEPRLSPSTPPPNKLPANGNVSFHMSRICVNNPNGPSKGHHNFQRAKKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M476</accession>
    <name>A0A1D2M476_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004709">
        <property type="protein sequence ID" value="ODM87776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M476"/>
    <dbReference type="STRING" id="48709.A0A1D2M476"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="80"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="28315" checksum="AF6F1B87168E4695" modified="2016-11-30" version="1">MVIKLEPDEVMALQKFKVVVGDLDEDDNVLIRFLRARDYDIPNAEKMLRNAVEWRKDIGIDNYLQWEFPPNYPSDLNWKYFGTDNDGAGICWMVAGRSNLKAILDRGEYDSALRWSFVMMETGLKLFAECGIPGLVVVDMEDLPYNKATHIPSLKILYEGLQQFEKCYPEMAKKIMIINAPWVFTIVWNFVKGVFGQKTRDKIHIYNSSNKAEWFAEFLASMPRESIPPEYRLDVFTSDNNNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4A5</accession>
    <name>A0A1D2M4A5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004654">
        <property type="protein sequence ID" value="ODM87808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4A5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="96" mass="10706" checksum="EB921C0CF7D3A5B3" modified="2016-11-30" version="1">MAKRVTRSMASDEEWLPTRGEPSRNTRASEACSSNKQRRITRSMVIALEKGVTDRTAVAMHSKTKIRKGSLSSKVRLPLLKGSIRRGNAKLNIILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5F3</accession>
    <name>A0A1D2M5F3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_18538</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01004040">
        <property type="protein sequence ID" value="ODM88144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5F3"/>
    <dbReference type="STRING" id="48709.A0A1D2M5F3"/>
    <dbReference type="OMA" id="WTEERIP"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM88144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="24188" checksum="4D470E8A8F12F761" modified="2016-11-30" version="1" fragment="single">MCANGTVISEWSYVPLDHEDPPVFISTWLEKVDDPGWKTYMKANKNIPFYAAIVYLLLIFGLKGFMKTRPAFELRKPLVVWNWTLAIFSMIGFYRMGQELGHNRFNATTVINYFVHSIVYPYFALRAMKIRVPRRLAMALTSLQLVQMLIGMLVNIYSIYVVSVQQEFCARDSYTIKWSIGVYSSFVILFADFLINRYFPKNKSKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5X7</accession>
    <name>A0A1D2M5X7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003675">
        <property type="protein sequence ID" value="ODM88376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5X7"/>
    <dbReference type="OMA" id="GECRRKP"/>
    <dbReference type="OrthoDB" id="8269870at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="17295" checksum="CA51D1A96C74C7DC" modified="2016-11-30" version="1">MGEKCKIAGQNEFLKPSEECEMSKGLHCQQYQQGNLCGCVIKSSLSWDEHAGECRRKPGQHCPYVNVTANPGAYERLSYNHKCHARADCVQVAPIPEAKLHKNKNSKTEQVSLCRCKPGYKESRDGLVCHSVSKAHNIPSATIMTFLVFITVRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5Z0</accession>
    <name>A0A1D2M5Z0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003756">
        <property type="protein sequence ID" value="ODM88332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5Z0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903508" evidence="1">
        <location>
            <begin position="22"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="123" mass="13907" checksum="5EEAE1307D67B206" modified="2016-11-30" version="1">MVVHIIFFLLATLLIWKQLKPAKVNSPSGFISFMCIQLWGSNERDKYKVELSLPNVLTTGTESGCKSSIKPFLFRWTLNAFTVSDAAWVLKTYPINVYIPVMMDNKLADKSKNTLSIDISLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6J3</accession>
    <name>A0A1D2M6J3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Stomatin-like protein 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003455">
        <property type="protein sequence ID" value="ODM88532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6J3"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="83" mass="9498" checksum="CAEA208FAC914E47" modified="2016-11-30" version="1">MPHQITEELFYNPDIVQTYQLLSYNCHVCGLSKRHGCRKEWEGFIHNVALPLMVVLYLRIKDPSTASYGVEDQNLAITSISSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8M9</accession>
    <name>A0A1D2M8M9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Metalloendopeptidase</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_17401</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01002754">
        <property type="protein sequence ID" value="ODM89281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8M9"/>
    <dbReference type="STRING" id="48709.A0A1D2M8M9"/>
    <dbReference type="OMA" id="HIHNFRK"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000015">
        <property type="entry name" value="Meprin A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 10 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="12">
        <location>
            <begin position="24"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM89281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="26447" checksum="86A5617950F06E7B" modified="2016-11-30" version="1">MKNPMLGEYFEGDMRFAKGYDIKSGIIGSRYRWPNNTVPYIISSSFSTDEEEIVLGALAEISEKTCIRFVQRFSQRDYVSIVRGKPNSGCWSYIGKIGGGQLLNLQAGPRPHCIYHGTVVHEMTHALGFHHEQSRTDRDDYVNILWNNIIPKFKHNFNKYSSSQVDSQEMPYDYSSIMHYDAYAFALNTSKPTIVPKSDVQIGQKKGLSALDTEKLKTMYRCKTPKFPYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M940</accession>
    <name>A0A1D2M940_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 6k1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_17223</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002627">
        <property type="protein sequence ID" value="ODM89459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M940"/>
    <dbReference type="STRING" id="48709.A0A1D2M940"/>
    <dbReference type="OMA" id="PMFNESG"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11056">
        <property type="entry name" value="CYP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000042">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM89459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="487" mass="56008" checksum="02565D26A316E004" modified="2016-11-30" version="1" fragment="single">FLFILNYKHGKYFRDRNVTYIGAGFPRLFRFLTGKIAFVEAEQILWNDVKKTGKSFVGFSDLISPTFYIADLELMKNIYIKDFDHFVNRRQFSTQDSDLLLKKMMISLEGEQWKGIRSKLSPTFTTGKIRRMFDIFDKSSQLMCEYVKKRVGSAGGEFDICESYSKYAMDVIASCAFGIDSKSFDCEPGVLSEFEEMGQRFQFKFNPVQFLKFLVLLIAPKVANQLGFQAFDTEPQKYFMRVIKDVMKRRRETGERRDDFLQLMMDAQKGLLKGEENSKETLECSLIGGFDTTQSLLIFAAYNLALEQDVQEKLLKEVRASFDANGGKLTYDGVLEMNYLDMVINETLRFMPPAARTERVCTKDYKIPGTDTIIEKGTMVSLPVLGIHRDERFYENPNKFDPERFTPEKKAERHPLTFAPFGHGNRNCIGMRFALTEVKAVVASLVYNFKLEPGTLTEIPVKFSNNTTLKPANGMWLKMTPRIASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M947</accession>
    <name>A0A1D2M947_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002631">
        <property type="protein sequence ID" value="ODM89452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M947"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="8885" checksum="3321B8E9FCAA15DC" modified="2016-11-30" version="1">MRSLYACIGKELYDERKSLTIMFGRLCSLCEVEDTDVELEYDYKHKEHNTSSSDSDEEHHKEIQKNLKTTFKSCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M949</accession>
    <name>A0A1D2M949_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002643">
        <property type="protein sequence ID" value="ODM89434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M949"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="202" mass="22922" checksum="09A974216485D00D" modified="2016-11-30" version="1">MPLGCLDEVQGNVDRLQKSIVINHIWIILVGCSCLMIQYFADPKYCTFTYSLLKSDNQFLRIVFGAHEFLFMLLAWNAYAASCSLCILQGITLSNTITKMTSQLNTLFSKTEIKLEKVKAVSFAEPFTVSKKVRFSQRKSDDNVEMLLLDYKQLMIVCNQLNGWIAYKTLFLHVCGGCQFVSDVFAATHILKLPGTGFMDVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9E7</accession>
    <name>A0A1D2M9E7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17130</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002550">
        <property type="protein sequence ID" value="ODM89552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9E7"/>
    <dbReference type="STRING" id="48709.A0A1D2M9E7"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000744">
        <property type="entry name" value="zinc finger E-box-binding homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376:SF216">
        <property type="entry name" value="ZINC FINGER PROTEIN 420-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="494"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="528"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="600"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="632"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="660"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="438"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="738" mass="84979" checksum="5CDA81FCBDAF66A8" modified="2016-11-30" version="1" fragment="single">LQKCESIAKRVGNQQPKTVEDDEVRIKVELDDSPLDEEDETFQFEANTNIPEENDSEDDTNFVATSKSDHDDDESEIEGNSDSDISSAASLLIHETTSESECSIETDSEEEQLIEPPTPPQKRRSPRKAKPLKKFRPRNNSLIKLNLFACEANGCRLHFQSIKELNTHLKTHSTTIHQCSECPRTFLQPEMLKLHKMVHTIKLVGRNYLCPFPSCRKTCETVFRAQHHYNIQHGLGLGCFKCHKCELNLASADSLKRHLKRHNKAKDPTLPINEVEHVLAPSPCSVCQLQFLRYRFLDDHRKEVHNLGVECPTCKKILSNRGAFLRHTYQIHRVNPEGYKCQYCPRKFTAKDYLNEHVVIAHPTLLNREGKLECQYCQTKFYRSYILKRHLNCCEKNPELETNLQSEKRDDFICDVCGQHFFNPRTLKAHARRHVTSSGVTSADRVKTRRKITRKIKAASGKLGRKRKKTLEPRERKRKRSSTTPFPAKKKEPVVCEICGESFQLRNFLTRHLHNVHNVPKPKPEQTYICDICGKIFAERGNLNKHQVVHTGERKFVCHLCPETQTFTANSALKGHLVKVHGKKKGEEFTVGEGNFRKKLKCKFPLCMKDFDSELELQIHVGQDHQGDNSRFICKLCGKVFKNQQRLTRHNEVHFPTKPYSCPICQKSFSQPNAVKGHLEGIHGQGKKQEWFPCTQPNCEAKFKILIYLHKHLREKHGVYTGKPRKVRVAENDGGGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9Z7</accession>
    <name>A0A1D2M9Z7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Prolyl 4-hydroxylase subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16931</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002399">
        <property type="protein sequence ID" value="ODM89752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9Z7"/>
    <dbReference type="STRING" id="48709.A0A1D2M9Z7"/>
    <dbReference type="OMA" id="KASHCAN"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF244">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="395"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="517" mass="59525" checksum="8C772F3BB54EA7DA" modified="2016-11-30" version="1">MEKYTYWANREEHIYLLLGHRLKYLHDEMQLIEKYLKDYEESSLKAIENAIKPLATSEERGKLIGASAILSHLMTHRYVFIVDGLRKLMSSKQYRDSQENVKSALDLTNEAEKNGKINGYKWPNEDDLFMSHTAILHMQEIYGFTARQFYKGLTIETSFGGVLKASHCANIGQAALTREYYYMAVEWLEFVLELLNEDETDNSISKDEVEPLLETVIKIHNDVNHLGETMSHEQFSNTYADVTYRNQPSKERIKGRHLNYALHGKTYGNGSDWDANNIALCSGQEFQPIEIRSKMKCFFERQLHPYFILNPLKVEQLSEYPLILQLYDVLNSKDIEEHYDVRRPFMQIAGFLNVTDVRLVTRYRTAAGGSLPSVPFTERIHKKSEMLTGLALGKEYDGLLVAEYTYGRYYSPHKDPLSASQTVNDIDIAGERLATLLYYLHEPEIGGYTPFTEVGIAGKPVKGSAVFWFNMHRNGTIKEGITHSACPVVHGHKIVFNQRIQYFQNFQKFGCSLNQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA41</accession>
    <name>A0A1D2MA41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DENN domain-containing protein 5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16833</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002323">
        <property type="protein sequence ID" value="ODM89847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA41"/>
    <dbReference type="STRING" id="48709.A0A1D2MA41"/>
    <dbReference type="OMA" id="DELMETC"/>
    <dbReference type="OrthoDB" id="6019893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17678">
        <property type="entry name" value="RUN2_DENND5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.60.20">
        <property type="entry name" value="PLAT/LH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047278">
        <property type="entry name" value="DEN5A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001024">
        <property type="entry name" value="PLAT/LH2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036392">
        <property type="entry name" value="PLAT/LH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46070">
        <property type="entry name" value="PINSTRIPE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46070:SF1">
        <property type="entry name" value="PINSTRIPE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01477">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00593">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49723">
        <property type="entry name" value="Lipase/lipooxygenase domain (PLAT/LH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50095">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="4">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="PLAT" evidence="3">
        <location>
            <begin position="135"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="RUN" evidence="4">
        <location>
            <begin position="310"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="473" mass="54004" checksum="B2D392DB0CAC942A" modified="2016-11-30" version="1">MASELNLNVATPGRGSRDPRRSPEKREVKPKPLEMPVLKPLPVSIAFDMRNIQAISEIKSEIGYARAWIRLSLEKKVLSRHLKALLADDELLRGFYKRTAFLRSEDEREHFLLHLLSLNTADYYCFTNTYVNIVLPYRMVIFPSKRFSISTTTANVWTSVSGTLGEMGPISVPKNTLEFMFQHKNLGLVTNMHIGHDNSGVSPKWMIDYVLIRNEVTGHCVKFPCGRWLGRDIDDGSTERLLVGEPYIDGEECPADTRLKTPTRARSPSVPRKPYESRLTPSEIQEGLSDTVNKIVKYFFQSEKDRGSLTVLLCGDNGLVSALEQVFLFGFKSSRVFGKNIYLWDYFVKVQEVFGRKVTNEDFELIIVNDDSSESSEHVVNVSLYCELIRKISFYASSLGKDGKFQLFICLCAREHLLPRLPQIMANLDITREMYDDHSFLRNPDLLQDMVQVVLALDDYDIILKHSLTKGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBK4</accession>
    <name>A0A1D2MBK4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002043">
        <property type="protein sequence ID" value="ODM90309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBK4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="17580" checksum="EF3BF46100BAB96E" modified="2016-11-30" version="1">MQKDGPIQVVPENPTKLVWSSLTLVIHSWKGQHVGRCLGQQGTFVFGLEGEHLSFSNNNENLTNYQILTDPQQKAEWKRVTGEFNPDSCNAFIANRDKRNEKNIYVGKVTYETGDCAVGTILRSATAAGGPGAAWILRHPIASNHDNQKEIALNGAGYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDB6</accession>
    <name>A0A1D2MDB6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CARD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001706">
        <property type="protein sequence ID" value="ODM91006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDB6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001315">
        <property type="entry name" value="CARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50209">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CARD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="408" mass="44596" checksum="429EDB74AB122282" modified="2016-11-30" version="1">MLDNERIVLKENANLLANLLTENVPYLLANYLQNGVISENEREAIISASSAHDIKIKLLETLADKEEISLQSVMQGLEATENHCVSKEIESLLAGKSDNEQDQEVTDGSGDRLEDVNAYATNLVDDVIATAEETTSNQVSQEELEPVVLDDVGLTETEEVEPIDSGAEVDPAEENLVEASVEVHKVDTEPPQSEDESGDAVDKSVTFPERVATVIEDHKRVEVTDHHEEQPTADEDGDYSSHGLDARNESENEDDQIDIEKEFVMPTEPETNNNNDLASDHKQTPVLTRMVSNEIIIDDEDKPSSPISKEPVADGDGDGLDALMARKALVRQQVEKFEKTAPGGGKGKVQYSFRSSTQESEAKAAEEEGSKVKNLKNFFQRLSTSESNTPPPAGPAKSVGKLKVTFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME44</accession>
    <name>A0A1D2ME44_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 4c3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_15395</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001604">
        <property type="protein sequence ID" value="ODM91286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME44"/>
    <dbReference type="STRING" id="48709.A0A1D2ME44"/>
    <dbReference type="OMA" id="PAKMNRD"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20628">
        <property type="entry name" value="CYP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM91286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="500" mass="57811" checksum="88E6BF043C8B60D2" modified="2016-11-30" version="1">MFWPILLLSGLLGYLFLIKLPKRLSLLNKLKAIPGPPSLPILGNAVDLSVHKREVLSVIGRFFQEYGPRFKMFVGMQPYVILANAADAEKILSSQTQIEKSGDYDSLQEWLGLGLLTSKGEKWFQRRKQLTPAFHFKILEDFLRVFNEQCNIFTKVLERKGKLVFDIFPVITLCTLDIICETAMGKSVFAQQKSDSEYVKAIYRISELVQYRQLRPWLHNDFMWRLSSAGKENRKCLKILHGFTDMVIQEKKMERKNGTRKSDETNEDNFVTKKRQAFLDLLLDAQQTDTTLTDQNVREETNTFMFEGHDTTSAAVSWTTFLLSLNPEHQAKVQQELDEIFAGDLEREVTMTDLARMKYLECCIKESLRLFPSAPFVGRKLNMELKLDDGVVLPPGITVWVYIFFLHRDPKVFPDPEKFDPNRFSQEDAEGRNPFSYVPFSAGPRNCIGQKFAMMEEKVLLSSIFRRFRVKAAERLQDVNVLCDVITRPEMGLHVTMKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME84</accession>
    <name>A0A1D2ME84_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001644">
        <property type="protein sequence ID" value="ODM91171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME84"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="24539" checksum="3C41F7468718AFB3" modified="2016-11-30" version="1">MTTTLMKNDMTFNDNPSDDDDFDDKEEIKFVTDFNPLDFQLPQRNHSISNTSFGPKIRTYFYICQQCSFQSNTKGKFEAHQKLHEEGSRAISCHECGRPVLPEQLERHRAKHSSMGYYQRQQSTLTVEESTVMSTSTTSQSSGKYFYQCSSCPFESNNSVRFGIHSKLHEEDSEAISCTECGFYVDPKKMTRHHAVRHKRKLGEYKTNRTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEK0</accession>
    <name>A0A1D2MEK0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding cassette sub-family A member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001545">
        <property type="protein sequence ID" value="ODM91446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEK0"/>
    <dbReference type="STRING" id="48709.A0A1D2MEK0"/>
    <dbReference type="OMA" id="GEWTHEE"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="17"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="16308" checksum="41343F07E135490C" modified="2016-11-30" version="1">MLKLFCHLRGVPSGDVNGQVNKWLRKLGLFKHGDTECRTYSGGMKRRLSVGIAMIGDPQLVFLDEPTSGVDPVSRRQFWRLISDAKGLGQSIILTSHSMEECEALCQRLSIMVNGQLQCLGGVEHLKDKFAKGYTLVFRLRKPWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFA6</accession>
    <name>A0A1D2MFA6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (cytosine(34)-C(5))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.203</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15037</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.203" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01001465">
        <property type="protein sequence ID" value="ODM91643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFA6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFA6"/>
    <dbReference type="OMA" id="QLFTEYV"/>
    <dbReference type="OrthoDB" id="6093671at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016428">
        <property type="term" value="F:tRNA (cytidine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057285">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057286">
        <property type="entry name" value="PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023270">
        <property type="entry name" value="RCMT_NCL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25376">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25378">
        <property type="entry name" value="PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02011">
        <property type="entry name" value="RCMTNCL1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="13">
        <location>
            <begin position="56"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="664"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="664"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="175"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="714" mass="81529" checksum="7F5AE13BAC9BB637" modified="2016-11-30" version="1">MGKSSAKRWKKKKNVEAETNEKGVRKQYEEIVKENADFETYYKLQKICPENEWEDMMKHLRESLPTTFRITGSRTEGRALLHVLQKHLIKDAVLAGKSDPEADIGAFPLPWYPQNLGWQINLTRKDIRRNEAYFRLHNFLISETETGNISRQEAVSMIPPLALQVEPHHRVLDLCAAPGSKTAQLIEMIHGEDEGIKTDGFVVANDLDNKRCYMLVHQGKRLLSPAFIVTNHDASRYPDVVKTDENGVLKKFKFDRVLCDVPCSGDGTIRKNVDVWKKWSTSNGLYLHQVQYQVLKRGLELLEVGGKLVYSTCSLNPIEDEGVLHRMLKDAEGSVELLDIDLPHLKHSKGMSHWIPCTRDMVQYSKFEDVPEKWQTTVRPTMFPPTPEEAPKYHLDKCVRVLPHKQDTGGFFIALLTKTRLLPWENTEVEVKSERDPPPAAKRDPRGPPKKIRRIGGFKEDPYVFMSEDNPIWPQLRDFYGLDTSLDCTNFLRRSEDGKIKNIYITTKAVRDFVRSNEKDVKIINVGVKALVRVDKKWTPCDFRLSQEGLPSLSPFIKDRRVQLPKEDLKAVLLNDDDKDKPPLLELLTEETRKLVEPIERGSLVLDIDLQVEDDGPLCKLQLVGWKGTNSLRAYIQRNDRVHYLRLCGADVSKYEKNKFKEREEAEAAELKKGDAEAEGNDNSMDVEGNGNGAASPEESSDVIEPKPIKVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFR1</accession>
    <name>A0A1D2MFR1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001435">
        <property type="protein sequence ID" value="ODM91741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFR1"/>
    <dbReference type="OrthoDB" id="6093252at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="62" mass="6732" checksum="18F623CD8D9D937F" modified="2016-11-30" version="1">MIGAVVKRAVTSRSHSGSKEDPLPPHFREGSHRYLLATCILATPAWVVTHMDDYRGGAVGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG87</accession>
    <name>A0A1D2MG87_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001355">
        <property type="protein sequence ID" value="ODM92008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG87"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="12909" checksum="887BC834388120A4" modified="2016-11-30" version="1">MDYIQPNQATLKFLPLLTPHREDKLLQSLLQLIVQRGQRMHVMQEEKERASQFSLYSIQRKKPLYIVDALALYSPRLWIRKNKKTSEQATKERSREAKKIWMQLKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHY4</accession>
    <name>A0A1D2MHY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">T-box transcription factor TBX1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_14075</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001191">
        <property type="protein sequence ID" value="ODM92606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHY4"/>
    <dbReference type="STRING" id="48709.A0A1D2MHY4"/>
    <dbReference type="OrthoDB" id="7442607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001708">
        <property type="term" value="P:cell fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20187">
        <property type="entry name" value="T-box_TBX1_10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.820:FF:000006">
        <property type="entry name" value="T-box transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.820">
        <property type="entry name" value="Transcription factor, T-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046360">
        <property type="entry name" value="T-box_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036960">
        <property type="entry name" value="T-box_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001699">
        <property type="entry name" value="TF_T-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018186">
        <property type="entry name" value="TF_T-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11267:SF195">
        <property type="entry name" value="OPTOMOTOR-BLIND-RELATED-GENE-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11267">
        <property type="entry name" value="T-BOX PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00907">
        <property type="entry name" value="T-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00937">
        <property type="entry name" value="TBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00425">
        <property type="entry name" value="TBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01283">
        <property type="entry name" value="TBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01264">
        <property type="entry name" value="TBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50252">
        <property type="entry name" value="TBOX_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="T-box" evidence="8">
        <location>
            <begin position="340"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="247"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="522"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="548"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="594"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="652"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM92606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="681" mass="72687" checksum="ACBEDB04FB1115E7" modified="2016-11-30" version="1">MKSPQASSVVSSLVCHGETKSKSNQNNPDISDSPTVGEQTSTIVNNTNIGGPDSKCGLAELTLNSAAASLCPSSSSSASSVCSQEDVSPPNSPQIEHPLFTPGAALVPLHSSFPSHYTHHLQPPSSTHSFYPHHQFFPGIPTAPTIGIMDTDPLNRPLVPGANAEFCCDWSTTSTYSSPMREMEACLLTAGKGRSPHHAHYSTPSPSTQRGDASPLSIHNVHNLHHHHHSHHNSHPLSQGQNAQQGMLYTGSGLSKPVDSHNSNIPFSMSSDSATSNNNVIVNSRSVSKSPMDQSHQHHANSSSVVGNGKQSQTSTTSSTPNQGAKLVLHQKLMNVTATLEMKALWDEFNELGTEMIVTKAGRRMFPTYQVRIYGMDPMADYMLMMDFIPVDDKRYRYAFHSSSWVVAGKADPNSPPRIHVHPESPTKGAQWMKQVISFDKLKLTNNQLDDNGHIILNSMHRYQPRFHVVYVNPKNEDVSQSENFKTFIFAETKFTAVTAYQNHRITQLKIASNPFAKGSVVDGLGHSGTPSGPNNVPTSGSNSSNLQVNPQSSVVGSSSGATGANNSNTSSSGQSRASSATKESPSHQSNGVSSTNNAAASGITASSNSSANNSSTNNSSSRLNNSQHQQQSSSHQQPSSSSGGLTPRATAVSSFTMHSSEQQYSASAIAASKDVKVSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIG5</accession>
    <name>A0A1D2MIG5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase dhs-27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001149">
        <property type="protein sequence ID" value="ODM92790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIG5"/>
    <dbReference type="STRING" id="48709.A0A1D2MIG5"/>
    <dbReference type="OrthoDB" id="8250698at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="135"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="422" mass="48607" checksum="C327F027527EC22C" modified="2016-11-30" version="1">MADIICPGPLLDCKTGAMNNEKLNGILTENGILSEVIGVKVDMEPELPAHFTSICQFVTVQFSNKSQENDLELFVKKLKDNAEIKEDDDYSLFEKESNVYTQVMPALRDFCESRLGSTKLLDMFPKVFYVGEQEIIMENLVKHNYVMLDRTKRHSFHEARLVVSHLARFHSASYALIQNIGLEVFKKRFPHTRERMMNRDGIGANINTLMIDSILTKLCCLLKNSNIKGSSSAYKRLEKYTSKAFSSMCDVVEETHLLYVLNHGDLWNNNILFYQDSNSNLTHLKFVDLQMNRVGSPNMDVGYYFYNSLKPQVRRKHITSLLRLYYEEFKLRAKELKATVDFTFQEFLQDYGRISKLGFIFGVYIAAASPLIGKVDLENSKNWIEDFVSAISQWLDNNPRERDGVLQEIIAMTQDFLLLGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIL1</accession>
    <name>A0A1D2MIL1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Cytochrome P450 6k1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_13836</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001134">
        <property type="protein sequence ID" value="ODM92847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIL1"/>
    <dbReference type="STRING" id="48709.A0A1D2MIL1"/>
    <dbReference type="OMA" id="DERYYEN"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11056">
        <property type="entry name" value="CYP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM92847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="527" mass="59453" checksum="44B755C18E0020EB" modified="2016-11-30" version="1">MAVLAIFGLLVVLGVAGFFYFLIHQRKKHGQYFRQRNVTFIGANFADTFKFLMGKRTLMEIETKLYQQAKETGQPYVGFSDIANPFYFVTDLELMKNIYVKDSDHFVNRRTLTTSQSDILFKKMLISLEGEQWKGIRSKLSPTFSTGKIKRMFDIFEKSSQRMCDYVRKRVGAEGGDFDICEAYSKYAMDVIATCCFGVDSKSFDCEPGVLSEFEQMGNKIQFRVTVSLIFKFILVQLAPKLADFLGFKAVNTEPQDYFMKVIKGVMKHRRETGERHNDFLQLMMDAKEGLLKNEENSKETIEVMTGSKEDTPANSFASGEESSPSKFTMDDDDIVANAVLFLIGGFDTTQSLLIFAAYMLALEQDVQERLLKEVNASLDANGGKLTYDGKPCATIHLLCGTNGCAPKIKIPGTDTVIEKGILVGLPVLGIHRDERYYENPEKFDPERFTPEKKAERHAYAFGTFGFGPRNCIGMRFAKVEVMAAISLLVHSFKLEPGQYTEIPVKMGNNSTLKPANGMWLKITPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ17</accession>
    <name>A0A1D2MJ17_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001101">
        <property type="protein sequence ID" value="ODM93000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ17"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="112" mass="12627" checksum="D06A8AF9359458D2" modified="2016-11-30" version="1">MSGLKSESSDSDVHISHENQKKINRFAIMNGWIEEIQDSLSAETDAADSPGGRRERPAAERRVDGEPRHADSSARWRVFRLVHQRRSAGAHPGSEGSHKEGDRRLRISREND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJX6</accession>
    <name>A0A1D2MJX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001049">
        <property type="protein sequence ID" value="ODM93185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJX6"/>
    <dbReference type="STRING" id="48709.A0A1D2MJX6"/>
    <dbReference type="OMA" id="ISRYICA"/>
    <dbReference type="OrthoDB" id="7837562at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="45"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="224" mass="25905" checksum="843A432D6EEB695B" modified="2016-11-30" version="1">MPKSRHQLTAECFSRDFNVDDAERFLKDDLRWRKSTKIDKLRLEDFADIASSYPVHIDTYDKNGAPVITAISGQWDLRQAHLSGQGQRAQLFLDKVMDEAANQVRRAQHEGKNVTRFHFLLNLDGFNLVQHGCPRCFIGILTFLRSYESHFPGLTDRIVIFNAPQTLQTLRPLVRSAISGHTRRHLKLFGTNKAEWQKYLLEFIDKDQLTEDFGGTRIRYADIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKC9</accession>
    <name>A0A1D2MKC9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Gastrula zinc finger protein XlCGF48.2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13252</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000992">
        <property type="protein sequence ID" value="ODM93430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKC9"/>
    <dbReference type="STRING" id="48709.A0A1D2MKC9"/>
    <dbReference type="OMA" id="FKRHACP"/>
    <dbReference type="OrthoDB" id="8113227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="558"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="654"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="693"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="724"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="752"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="244"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="794" mass="90591" checksum="BBC71E9C68DC2510" modified="2016-11-30" version="1">MELNFFCCSFCYKNVDEGELEKEEVDEVLAKFVKLARRYFGGKEMEHLVKLESCPQCFKVVTSFCDLYHQLKCIELEMEWRVSKLKEVMSSADKVEFRKDNFRRSWRKREEAGREAVEEFRKDFITKCSSPVSNSFPKVVLTKRRKKINREELEQCLDDPQSILPLLGGGPSPGKGMIMELVLVPNVQDSRSAAPPPPPLSIHSAVDDNYEEMSVDQDQPPSEDESELRISNVCGSVDLEKVYKPEQLEVSPPPNKSSTEPQLEIISVKVSPHLPEDASLEDVPPPGEVSSQLPSTSMPINLSSKATEPPVPPVESFEKVPLPSSLISSPKRSLRPRKLALTPKIKEEEDSSSSEKELENPPEDDNDDDFQADENTAEVESEEEAEEAPKKPKLLIPSTPSLFVSSSKETKKCLTCHLRFDSEQELSAHQKLHGSFPCSFSSCDFTSTYAPKLAEHELTHSTPIKNEPNSAPKSKKKGKGCKALKCPRCPSLTLSRTSNYINHFLETHLCLTSFKEITLCPVCHLSFFDIHHRNGRKCRRRHVEEQHNIKGMDEASIVRCDKCPAYFRRHMHLFSHNKKMHGGDALQCKDCGSKLANSYAFRNHRIEVHKLNPADFQFVCDIPSCSERFETERERECHKSARHNKNAKEDSDTMICTECGKTFAGPLGLKGHMRTHEKGFQQKVEENRKKMKEICDQCGKSFRDKHRMETHKQVVHLGPQHWKFECEVCGKKCFNKNKLEEHARVHLKAKSFICDLCGASYAHAHNLRLHKKNKHGKEVKKVFKKRSLLMMMMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKZ9</accession>
    <name>A0A1D2MKZ9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Long-chain-fatty-acid--CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13132</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:54537"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>tetracosanoate + ATP + CoA = tetracosanoyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33639"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:31014"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:65052"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:33640"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000956">
        <property type="protein sequence ID" value="ODM93551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKZ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MKZ9"/>
    <dbReference type="OMA" id="QICAVIC"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000020">
        <property type="entry name" value="Long-chain fatty acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904207" description="Long-chain-fatty-acid--CoA ligase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="9">
        <location>
            <begin position="60"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="9">
        <location>
            <begin position="245"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="10">
        <location>
            <begin position="459"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="582" mass="65177" checksum="40F4068164327A10" modified="2016-11-30" version="1">MAVVYLAILGVAVWTTVNYKQICAVICTLPRDIKGLVRLFKVFRLLKYYKLRNATVANIFDEMASRNPTKVLFYYEAQRWTNEPGSTSCTNRVSNYFQQEGFQKGDSVALFMENRPEFMCIWLGLSKIGVITALINTNLRLQSLDQSMKSVNCKAIIYNEELSYVLEELILNGSLAETQLYSLCSTSEAPSIALSVHLGKGLEEALDSPPENVSKSLKIAAEIIGLRARLPKAAVITNSRQFFILKIEDDDIIYTSLPLYHGAANMLGAGLSICCGVGLVIRKKFSASNFWADCVRYDVTVAQYIAQRLCRYLLAQPASAYDKTHKVRIMYGNGLRKEIWMDFVRRFGIPKINELYASTEGNCTMVNTEGKVGAVGFVPPYLNWLIPYQLVKVNELNGEPIRGKDGKYADQNASKSKVLENVFNKGDSYFRSGDILKKDIYDRFGDTFRWKSENVSTAEVESVLSAVCGLNDVIVFGVPVPGAEGRAGMAVIANQDGSLNLNALAKWVCKALPNYARPFFLRIVEDNVEKTGTCKLQKIVYQHQGYDIANIQDSKLYFLQGTTYVPLTQCLYNDIVQGKVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML29</accession>
    <name>A0A1D2ML29_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12922</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000923">
        <property type="protein sequence ID" value="ODM93759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML29"/>
    <dbReference type="STRING" id="48709.A0A1D2ML29"/>
    <dbReference type="OMA" id="WDGIMTQ"/>
    <dbReference type="OrthoDB" id="6134317at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03156">
        <property type="entry name" value="uroplakin_I_like_LEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000301">
        <property type="entry name" value="Tetraspanin_animals"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF552">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002419">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="26804" checksum="F6E54A56A5608E9D" modified="2016-11-30" version="1">MDLGTSLVKYCLCLFNFVFVVAGIALLGFGIWLACDYSSIVTLLKFAEHDTIREYGSATVIEQLGYVLIALGAFIFLISFLGYCGTIKESRILLGAYAFFLSLIFILEIVLVILVAVHRQEVEIESRGILTDSIQRFYTTREKANVFTVTMDIAMAQGKCCGVNNFSDFNSASQFQSNKTADQKIPIACCKLDGNPLNFKPVDPVCITNPTKENSNFQQGCFDSLISTLSDNFNMAIVAGVVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLK8</accession>
    <name>A0A1D2MLK8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">5-hydroxytryptamine receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12889</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000913">
        <property type="protein sequence ID" value="ODM93792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLK8"/>
    <dbReference type="STRING" id="48709.A0A1D2MLK8"/>
    <dbReference type="OrthoDB" id="10034726at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004993">
        <property type="term" value="F:G protein-coupled serotonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071880">
        <property type="term" value="P:adenylate cyclase-activating adrenergic receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF199">
        <property type="entry name" value="IP13425P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="181"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM93792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="248" mass="26060" checksum="56D8E5339EDB7B81" modified="2016-11-30" version="1">MSAGATTSFSFSTSSPSDIFRDQDQSDCSGKSGEEAINCANEQEIFSAEGAQGNSLSGSGGGGSIFDTLTRVIRETNGSSSSSSSSSSSSSVEAIFADGVLPFPLDIFGNGTDTLVYSNATDNVSRFIDAYDNPGPTTTITNWDGSTTEAGTLLGVDSPISWSSWVLVAIFTTLIVITMVGNVLVCLSVILVRKLRKPQNYLLVSLAISDLFVAIFVMPFAVAFEVSAGTWPFNNALCDLWVSGKCNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLS3</accession>
    <name>A0A1D2MLS3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000872">
        <property type="protein sequence ID" value="ODM94019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLS3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="136" mass="15746" checksum="B7CCC50A49FCE52D" modified="2016-11-30" version="1" fragment="single">IVSPTEYFWKFQRAQEYETEKGGNGEDKLPGVRAKQALQFTPSLVADNKSSDQKEFKELQCLLEQLRNEYQDLKSKCAEETHRADFNEGLVKSLQNDLQNLKRQAVRKDSEMDLTDDKSDTEDNMIVDDDSKTHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM75</accession>
    <name>A0A1D2MM75_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000878">
        <property type="protein sequence ID" value="ODM93975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM75"/>
    <dbReference type="STRING" id="48709.A0A1D2MM75"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="128" mass="14461" checksum="584828BFAEF1C0AA" modified="2016-11-30" version="1">MVGLPFETGKEVSSIIKSHILVGHSLKHDFAVLYFTHPKARTRDTADYFKKILHTKTPALRTLTKKILGVEIQQGEHSPIIDAQATMALYRICQKDWEHSVRQKNRGVDILKQTLDEFKANAVASPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMT5</accession>
    <name>A0A1D2MMT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000837">
        <property type="protein sequence ID" value="ODM94242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMT5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="19003" checksum="8E66E584AF3C6FDA" modified="2016-11-30" version="1">MHPNPCPCMSLQTGVKLVAVVHAVAHLLAIVIFTSGAIGLDLGIDAPTTNQFIQEVASNGKPMFSLVFFFYLNAVLLSIVLYFGAQKRNTGMCWAWLGFSAFHLVLALGIMNVIFVLRASDFVVVVVEIYLLFVVYAFIMQLRQQAREELSTVFALKTPAGAKAQLQGSIYWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNM8</accession>
    <name>A0A1D2MNM8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-dependent DNA helicase PIF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000769">
        <property type="protein sequence ID" value="ODM94679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNM8"/>
    <dbReference type="STRING" id="48709.A0A1D2MNM8"/>
    <dbReference type="OMA" id="ANAMTIN"/>
    <dbReference type="OrthoDB" id="7762548at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF6">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="544" mass="62186" checksum="C5D3E3878AD97594" modified="2016-11-30" version="1">MTNLLDYYAMRPENMEEVTLAEFASMYNVSKINKSCSSSSETAAQDFSNKRQSTTSNNRVDQFLPPRFITTQDYHNMMRELNEKQRRLVLDLMHRLKRQETFYIFLSGGTASDAQKTKFLEYAKTLTVQQCSGLRYEVNLQVGAEYFISTNVDVSDGLFNGATGTLKLIEYGLTREGIAIPKRVWMDFKNPQIGITKRHAKRAYQVSKGYDVAWVPIERITMRISLTGRNRAVELIRTQIPLVAANAMTINKAQGSTIRQVVVSVRRNLSREQMYVACSRASSKIGLYIDGIFNPPNKPDDKKQQKVSSEMTRLRGSPLNMTIRFLQDYDDSFLKLYVHNIESYLRHFADLFADNCTKASDIIGIIEPQLLETDQLHTAEFEVAHRVNCSEKRNSEGVLLLKKNETEVYDIHNHTLRLAEGHCFFLTWKIGIVTFVLTYKSPKFSKRVYMENLASIIDGNEKVVVFGDININVLDGQSSAFMEVMKKFGMSSVLNLQEYTTNGLTNIDVCFTNLIGVSGWIYESLYSYHKPLCILIPKKICEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNV7</accession>
    <name>A0A1D2MNV7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000763">
        <property type="protein sequence ID" value="ODM94717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNV7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="90" mass="9944" checksum="1C8EC4CB7C813FCE" modified="2016-11-30" version="1">MFGIRQNNQTPSQRALVPEADEEDGNVLEGPPEGTSTRIKAARMAASIKAVEALFPQISYNGTHWVPPLPHHECRPNGTLLHDVHDDIDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPK8</accession>
    <name>A0A1D2MPK8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fatty acyl-CoA reductase</fullName>
            <ecNumber evidence="4">1.2.1.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11637</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA</text>
            <dbReference type="Rhea" id="RHEA:52716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="EC" id="1.2.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the fatty acyl-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.84" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000718">
        <property type="protein sequence ID" value="ODM95040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPK8"/>
    <dbReference type="STRING" id="48709.A0A1D2MPK8"/>
    <dbReference type="OMA" id="THEWRFH"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102965">
        <property type="term" value="F:alcohol-forming long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080019">
        <property type="term" value="F:alcohol-forming very long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05236">
        <property type="entry name" value="FAR-N_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09071">
        <property type="entry name" value="FAR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026055">
        <property type="entry name" value="FAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033640">
        <property type="entry name" value="FAR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011:SF116">
        <property type="entry name" value="FATTY ACYL-COA REDUCTASE CG5065-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011">
        <property type="entry name" value="MALE STERILITY PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03015">
        <property type="entry name" value="Sterile"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="7">
        <location>
            <begin position="142"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acyl-CoA reductase C-terminal" evidence="6">
        <location>
            <begin position="458"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="622" mass="70456" checksum="28D5E3260C630FC4" modified="2016-11-30" version="1">MMNRKKSSRPGPSSSCVSSSGSSRQGSRTEELGAEDGRGDTRARPSVVDEQEEEQGPLIAGIDVKESPCHSWSSPFSFFTTAGQGKVATGAWSLSRRFPEPSFNGDVDNWAFKMDRPTTPITAFSKIEAFSSQEPLASWGKLRTCPEVQTVYILIRPKSGSDVQARLEELLDNSLYDTIRQDDPDVLKKIVPVSGDITLPYLGISEQDQQTLAEEVSVVIHSAATVKFDEKLKLSINVNVQGTKRIVELCKRMTKLAALVHVSTAYANCEREEIDEIVYPPPADPNKLIQCMEWMDDDVANWQQAEYVHVHQGISRAYFDSGGYKSPIVHCRPSIVTATWKEPVAGWVDNVNGPTGLIAACGKGVLRTLLCHRNKVADLIPLDFPVNLILSAAWYTAEHKNKSLQLLYGNSKPLLWGDLENWGFKHLVSNPLSDVLWYPAASFKTNKVWHNINDFFIHYVPAYMMDIFASLTGRKPVMLKIYKKITKAVQSLQYFTVNQWQFNTDNMVALYEFLSPEDQRMFSFNVREVNWPTYMENTASVFHAAGCSKTCSKSKKLRFKKNLCVCFLCTKLYWVHKFTQFFLILIFWRAIMFRCETARQLWSFMFGMVLRMARMLPIGEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPP3</accession>
    <name>A0A1D2MPP3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000741">
        <property type="protein sequence ID" value="ODM94841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPP3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="546" mass="57264" checksum="18515B87BB705BC0" modified="2016-11-30" version="1">MVVSKTPHSVPKMPESRAYTLQSRDKSLTAQKKKNGADDSPPREHFRTMADSKMKHSYSLTSLSSRFLHGASSSGTSGQQTNGHHAHNSLTNGHHGTAGNGNGNSMMLNGKDGGELDGSDDYGFLSYNTARVERDNASKLSSGPTSAKSLTSSLHNNSNFTLGSSNHNGNGGGVGSGSFYSTATYGRLKHSSQQQQQQQQQLHHPQCQHHNNNNGGVASGAAAPSSSSGGGGVNSTSKYEMLRNNFFGSGITRERDPKLNSSCQALNLCANNNGSSNNSNGTSNGNASSIFGASSINSTVSNNTNNNDSLMNGLTGSSASKVGSRTAGTRVRRTISCYAKNPSKLDSLENNLSQQAAGFGISEKDYLGSSMMNMSSTNNSSSHLHHHHHHLSNGNHHHGSINGFIAAPASSGLNGHAGGLGASTASIVHYQPGPAAGTMNGHHHHHHLSSATAPGVAGGPNFPNPICEFSPFSSMSSTDLIGLRMTNGFGAGGLDRRYVGSNGSANFTVYFHDNPIDCGCSTCFQVKLNIFQSKEKKLRLLMPDMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPV6</accession>
    <name>A0A1D2MPV6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">c-Myc-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AMY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000712">
        <property type="protein sequence ID" value="ODM95097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPV6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPV6"/>
    <dbReference type="OrthoDB" id="524165at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026060">
        <property type="entry name" value="AMY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13168">
        <property type="entry name" value="ASSOCIATE OF C-MYC AMY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13168:SF0">
        <property type="entry name" value="C-MYC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19252" checksum="38521DBC9311A97D" modified="2016-11-30" version="1">MFAIAPKNIAAGGASLEKPGNFFALLSAAATAAKQQKRAVPDFLEYLNKSGFKTAWVRAIVALYEEPKKPDDPLAYILKLMGLGIPDKTDVKRMQVQAKHLRTKLLQLQHDNEVLKEEIAVEEEAAHQRKELVNLYDDGKYFSEYNSDEDYELHNTVSTYNPDKAGGYFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ03</accession>
    <name>A0A1D2MQ03_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000706">
        <property type="protein sequence ID" value="ODM95147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ03"/>
    <dbReference type="OMA" id="NTHSFNY"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="19357" checksum="9C73ADD0C62C7470" modified="2016-11-30" version="1">MFSERQGGSGAASTADIDDLRKDTILIVAVVGGITAGLVAIVIALAAIICRRLSSLNKKLDLIKISLKSMKEDMTQTNAAIDRFPKNIVQFPMTKSNMMDDDDRAGTEPASPIFYRKGFTATPLATSLQSVTEVPGENQSVHHPLQRNNAMLPVRVKQPGPPVPPKRAHSFNTHSFNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRX8</accession>
    <name>A0A1D2MRX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000652">
        <property type="protein sequence ID" value="ODM95564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRX8"/>
    <dbReference type="OrthoDB" id="28397at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13231" checksum="A8065C299567532F" modified="2016-11-30" version="1">MDQSQTDDIENWISPEMWSDPWRYLTTSERHQDESSTSFLSTPQREMETGTKFAESDFDVTDSVPSKLNAESINPNASSTTSVENSELDTKDQESNLNIDSKMESASRSENIDLLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS89</accession>
    <name>A0A1D2MS89_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transforming growth factor-beta-induced protein ig-h3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000619">
        <property type="protein sequence ID" value="ODM95792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS89"/>
    <dbReference type="STRING" id="48709.A0A1D2MS89"/>
    <dbReference type="OMA" id="NCHRIIR"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000032">
        <property type="entry name" value="Fasciclin domain-containing protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF114">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904458" evidence="1">
        <location>
            <begin position="20"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="93"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="234"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="369"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="504"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="674" mass="75712" checksum="EA94496B91176181" modified="2016-11-30" version="1">MLPKLVALLLGICVVLSYGKAPRVPWWQLKVAKSQGPNACIVEEVPELNKKYWTECKYWPVRKVCGKDTLIRYECCEGFKQLPDEEGCTGVKPLKNVLETARELGAKKFVKYLEDSGLAEELSRPGTFTLFAPFDHAFDGYLGTQISMKIQSFRNSGDNPVLRYHIANTKLPSKDFSGNVELESQYEGRKLRISKYSTGMEAVNCVLISRKDQEANNGIVHMIDSALDPTLLIPRDVAQVVVEDGRFARMSQAMQRCGFMDRLRESSRAFTVLAPSDEAFLKIPPARFEKMVQDRDSCVALLENHVIPHAMCMPVITEEYRAKSIGPARIAFDCDARGNTVENKRLSGELILGNNGVVYMLDDVLIPDRARTLLELAETRHLQTFVQLIRIAGLDDLLNDFGNYTLFAPSEEALYAIDKEILNSARTNRDLARKLVLYHALPGKIMSNSIIHNQNIVTLDNENSVRLVVYRKSYGLEDALIEQSDIEGMNGVLHIIDKVIFPATESAGDILRKSSNYSMFLHAMEQVLESDPQAIDLRRGQATSHYTFLVPSDDAFRAIGAARLRRLQTDTAYMTKESCGCMKIICVFIFNPQKNYEANTIKSVIKNHVSQSMMASQAFRPNLTYEVPTRQNALGLCKRNGKLTVNKEANVVKQDIVSSNGIIHIIDKLLLPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSH4</accession>
    <name>A0A1D2MSH4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-tocopherol transfer protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000588">
        <property type="protein sequence ID" value="ODM96047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSH4"/>
    <dbReference type="STRING" id="48709.A0A1D2MSH4"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF130">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="55"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="21710" checksum="1D3B1F6908FB0FF2" modified="2016-11-30" version="1" fragment="single">MRFLRFKSEPRRAYETLVKYHDFRKSDKNFFSQMRPSAMKYLLDSKVITKLPGNDVKGRPVLLLNFKRWDQEVCSVEDIIRLIMLFFEEIMRTQGSFPISFKAVHQVNQSKTFWLVSKILFSFFSAKLKNRMHIHGTDRESLAAHIPLSSLPVDYGGTAEGDVDTAFIDEMYKNEQYYEALANFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT78</accession>
    <name>A0A1D2MT78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA topoisomerase 2-binding protein 1-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000580">
        <property type="protein sequence ID" value="ODM96098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MT78"/>
    <dbReference type="OMA" id="NVHCLKT"/>
    <dbReference type="OrthoDB" id="251770at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17738">
        <property type="entry name" value="BRCT_TopBP1_rpt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000018">
        <property type="entry name" value="DNA topoisomerase 2-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561">
        <property type="entry name" value="DNA REPLICATION REGULATOR DPB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 2-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="29"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="126"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="281"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="459"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="549"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="1180"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="642"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="890"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="948"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1068"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="427"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="643"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="748"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="952"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="987"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1109"/>
            <end position="1118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1368" mass="152405" checksum="7E0CFEFF1E2CA987" modified="2016-11-30" version="1">MSLIFGPQVLRSVFNAPDILQFVTMSHPTYALAMRKMIISLSGFSRELKSELEERIRLMNGTISPSLTKSVTHVVTANAITNKSMEASREQIPIMIAEWVKKVWKDNQSRPVQASDPRYANCFCPLFYKVKVCLSQISAAKKATLKAAIERLGGTCSPDLVKGTTDVLVVTNAAGDKFKFAKRWKIPCVTPDWVENSTDQGVLLPFKNFKVIEDVDLAVMMSTPAHSHVPDLSLNFTRCSAVEDDQSKLVIDATTDFSRNNMETFNSHNDAVAQLKAAAKNTGSYLDGCRIYVVDYENCDELKRVLNTSGAVRLNQLSNGVTHVIVTKEKLPKLVQDRLNDLEPMPYLVTIEWLLESAKQGSPADEDLFKFETVVNVCQESFAVPAPPSRRPSVSIAPELSTRQSAMDNQQQGSRSAERLHSSSGPTTTTTDTCTEDSTTTQDDDNESYSTTNLTENEEDRGLFAGITFKVVLLDEEERRVSEEVIVENGGVITQQNPEVMILPTVCDQRLKDEADQSYTKYWLADCLESKSLDITPSYQYVPMVSFKRMNEVMKNVVVAISQYSVTAEREYIVDLLKAMGGRYQDVFARKAASDKKNERSTHLICKNIDTEKAKAAKRWGVPVVVAEWVLDSFIQRKRLNEEQYNPEHQNTSDPTVYMPTPKRAQTKKLKTSMLSVQSIYPPSERKAAPSEVIGKNKQTPEPEKIEEASPVELEPKKTKGGNPEPRNDAQNGFRTPPHPSTSKKQHNVSTSANPTTDARVDEDEDEDSFLRGLPKCLPQAEVDRIMAEFKAQDPYTDESFERMMEDLKARGINLDDYSPFTSMEERRLCDPNPDSPLLLGLPRHESRALKEQYEIALTFSPVNRIKLKPRMSTPLSELVERLNSVIRRQDSVSESPVQGHSPRASTPRAGATPLRKVAAINRHSQGALTTPHNQMEVIDPLAGIRRLSSKRPSDGSPEKDDESKASKRARCSSESHNVEIIELETKSTPTTDNVEVTGSDEVDKPKPATSKLSNRMQTLTNLIAQTQSDNEERASPAKRRSGSDSVINLIPPNAEEEVCEEIDQPHLSWADDDQPTAGKKSTVKKVPPKPVIVPETQPKVQENSERASRKRSSRIKKAGSVVNLEDGSNRVTRATRSRSKTREESVPMGHQPIRIEKGKKLKRSKGNTFPIDLPENPQFMVSSMSEPEKANVTEMVNQLGGSISTKSCFDPQCVGLITGSLIRSEKVLCCIAAGKFILKTEYLNQCVVAGKFLPVDEEFLWHEGNINQEKERELAKASFLWLKAQLLDTTKKPMFGMKFLILDQPPTKLDAFTRVVLSAGGKVVTNIEEATCVIKEEKSKSSVVVPNGIPVNGPMYLNTLILKDPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTZ5</accession>
    <name>A0A1D2MTZ5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NTF2-related export protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10406</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000556">
        <property type="protein sequence ID" value="ODM96274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTZ5"/>
    <dbReference type="STRING" id="48709.A0A1D2MTZ5"/>
    <dbReference type="OMA" id="QFVEYYY"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000005">
        <property type="entry name" value="Nuclear transport factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="3">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="131" mass="14806" checksum="6F0C4B2576D75466" modified="2016-11-30" version="1">MANLNPQYDTIGKAFAQQYYGLFDNPAQRPNLHNLYSETESLMSFEGQQCQGAAKIMEKFNSLSFQKILHIITSVDCQPMFDGGILINVIGQLKTDDDPPHTYSQTFVLKPLGGTYFCQHDIFRLGIHNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU03</accession>
    <name>A0A1D2MU03_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heterochromatin protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000531">
        <property type="protein sequence ID" value="ODM96523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU03"/>
    <dbReference type="STRING" id="48709.A0A1D2MU03"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00034">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="124"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="66"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="20759" checksum="79DDB61B24258415" modified="2016-11-30" version="1">MDSFSSLSLGSEEYIVEKILKKRIGADGKPSIPQVGGYGHDENTWEPQENINASFVSAFEKELEVKEKEEEELKRKKEQSNKPSTSNKSRAKIPSTEPSSNQQKKPSVQVADDKPNVSGFDRGLEADEILGANNENGGINVLIKWKGNNGVEMVPTSVARFKCPDVLIKFYEENFIFAMSASKTCIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU17</accession>
    <name>A0A1D2MU17_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein saal1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000521">
        <property type="protein sequence ID" value="ODM96599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU17"/>
    <dbReference type="OrthoDB" id="8251639at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="502" mass="55540" checksum="406BC3C9F8C205B7" modified="2016-11-30" version="1">MNYEDSSSDDVPYLPPDQFKTYEQRVSGQFSQNSASDQNQNPVQSSQSDQRRGRSHFTDDELRELDLPIGAQSHHVGAISSIPRPSSPSHTETGWSTVDLSQPTPSNLDNNMRFHYAREPSLQSSKISWGRRTLGILLIMIPAVLFSVAVHFVDWSMSDFQLYSASFFIFQGIFWPSFGMLLIDLFCTSKTHADSSSDPPKRSNPVGNGNKQIPKWLLTIYVVIHGNLTAATIIFQLLSIQRLNISVSLALSFGFDVVVILIQYISTKRRCSLELLLLSIVSYCGYGVVAIPAFISSDHTTRNDTAVGVGASVGVLLLSIPATFLLSHIRKHQVGDSIVGTTTAFFGIIQSLITKEIIGSALNLRLESRSVGWAAGLISVVFLGVIFLFLEARLSALIWQRDDDKPRNFSSVTRTRLAVFMLSCLWEVARQGFRDSAPEPFDILGGFLVMLSFLLSAGFQAWFNSSDGLNTADANTGSSSPRGTESRHKFFAFLPWLFAQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUE0</accession>
    <name>A0A1D2MUE0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E3 ubiquitin-protein ligase CBL-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000514">
        <property type="protein sequence ID" value="ODM96663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUE0"/>
    <dbReference type="STRING" id="48709.A0A1D2MUE0"/>
    <dbReference type="OrthoDB" id="7237699at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14318">
        <property type="entry name" value="UBA_Cbl_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="335"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="41265" checksum="1A807FD2DD3E6F0D" modified="2016-11-30" version="1">MNLQDVCGWSHVNNSLQALALSPRSETPESRVRVLMKSISQKRCFRRQSEPWDNTKGLPRVSRRALHQQEMNLRWRKPECNPGIASNSTSGIGSSASSTSGSGGTVAIGAGSLLNSNVFVSAASSQINVNVSSPVIPIIPPPLPPRKTSPSRKRTAVAHFDASSSSTSHSHSESNPNVTNGNDSSSRQQTILNRGEAVENGYDVPSTVRGSSSVLSASSSNSLPVSIISSTLRQQQVQAISLISGRPNTIKALRVNSSNNSSRFGINHVQIKWLKRTSSFNSQVLSIFIRRLTKLQPAYPIAFKFLQQIFLSREKKGVLPDFDASDETPTAPYENLNMDYISKLAGEGFSQDLIIRALGISRNDVDMARDILTEFAGSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUH9</accession>
    <name>A0A1D2MUH9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial import inner membrane translocase subunit TIM22-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000505">
        <property type="protein sequence ID" value="ODM96759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUH9"/>
    <dbReference type="OMA" id="LITEPYW"/>
    <dbReference type="OrthoDB" id="10534908at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="15490" checksum="ACF672379946ABD2" modified="2016-11-30" version="1">MPDELITEPYWQKCGSFGSIFVGTTGGIVLGALTKVAESKPLFMISDRPQVKPFLKKLPQLSQVTGAKNVYGRVALQALGCAYVYSFLECKFQRGHRRTMFDAGLAGAITGGAFGLRGKPGGTLGAVYGAAGFTAYAVIMQLLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUS8</accession>
    <name>A0A1D2MUS8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA exonuclease 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10006</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000513">
        <property type="protein sequence ID" value="ODM96671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUS8"/>
    <dbReference type="STRING" id="48709.A0A1D2MUS8"/>
    <dbReference type="OMA" id="VMERHEV"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF158">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="4">
        <location>
            <begin position="151"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="37208" checksum="DFC7E301FCB8B850" modified="2016-11-30" version="1">MMHLVLFQLKLRRCVMERHEVEVSTKRKIQPEAETEVTVSTPSAPPVQVRKTAVATRSTPNLNREDESKRKQSKSRWDSPIELKPIPESDDGKVVKLSETTTDSQVSSSPPSKKAKIDESLDVAPRNFPRWIKHAADSNHSSHKGVILVTGILAMDCEMVELARRRSVGEDSIVNEFGCLYDKFVKPDRPVTDYRTEFSGIREADLTNEFPFSEHCCLFSATSFQTVKKEVVDLLKDRILVGHSLKHDFGVLNYVHPEAKTWDTAIYFKKYPSSKTPALRTLSEDYLEVEIQQGEHSSIVDAQATMALYQYYQLHLKEWEQSGRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVM9</accession>
    <name>A0A1D2MVM9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Unhealthy ribosome biogenesis protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000472">
        <property type="protein sequence ID" value="ODM97109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVM9"/>
    <dbReference type="OrthoDB" id="160374at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052609">
        <property type="entry name" value="Ribosome_Biogenesis_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018849">
        <property type="entry name" value="Urb2/Npa2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682:SF2">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10441">
        <property type="entry name" value="Urb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904609" evidence="1">
        <location>
            <begin position="32"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal" evidence="2">
        <location>
            <begin position="663"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="822" mass="94010" checksum="EEEF960003911A93" modified="2016-11-30" version="1">MRISFDISIMVGLVALKLNWLALMEQRQCESTEETLLLENDPDNSVKVNLKRSTQATAKFVWNLQHLLIKGKDSCLNMSNESILHIASIYMDHEELVGYAKTYLDSIVLSHASLDAKITQEVQRYSTITFHVALVMEALHEGLQQVEKMQVMKRRIKKFLQDFLSPAFKINVLQNITRHEKMGSGELQKTVTEAVKVVNDLMSIKLTKEEVNDSSDRPPVLLKGIISFISQQELGQYPKPVKSMIFLGCAVIFTALVNCEDYKGIVEDLVVILNECGKKSQGNEFLFHIGWDNMFELVRRNVEFLSPESIKRMCSLVLENIYLSPKTTSQFLEKNAKATCEDFELTTPLGQLSLAVMEYILQEVEETKAKSTPMILNHAKELTNTAVSKLSDGSVITELHSLIRAFKKQKKKGAAVTNTAASISFVSYVMHTCYLLLKGKSCMSKEDASEYSVIVLPYLRFALDFLEAVETGGYGKIKSDEKLQLATPLFNCRRFSIESLKSFEEFRSKLPDEFLLRMWNCCMMNLKMEDDNYDKEFEKGLLKRLIEVSNEVEFQAICDSIVQQLTNDASELTLAANLLNILMEAEISAENKKPRRMTVEMCLHKYLEHIHLWQDSDQVIQVAAPYIEFQTKLLRRRKPMGNLNTLAVSMLSITELPLTKVEDVKTFSSLFSLASELMNAMTVHRLDVISYRTHVFLQCFQFLVENLVKKADQKNKLTDGEIYDLRHCGHCIERICQSTKLGRQEFTRVSPYLVVVLLQQFEKITVYPAVKNPLLNGCYKLLDMCDEKGISHVNSMLSAGSREIFKTVYEMYKKFYRYKGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXQ1</accession>
    <name>A0A1D2MXQ1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">26S proteasome regulatory subunit RPN9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">26S proteasome regulatory subunit S11</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">26S proteasome regulatory subunit p40.5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_09103</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the proteasome subunit S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000430">
        <property type="protein sequence ID" value="ODM97574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXQ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MXQ1"/>
    <dbReference type="OMA" id="ANKRTIT"/>
    <dbReference type="OrthoDB" id="1093at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054179">
        <property type="entry name" value="PSD13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035298">
        <property type="entry name" value="PSMD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22037">
        <property type="entry name" value="PSD13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="174"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM97574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="45127" checksum="750E337B7FCBAFB2" modified="2016-11-30" version="1">MSEKVYKYLKNKQVTAPPGLAEKWSDLENDYTKRLWHPLTLKLQEFIKEKSVEANHGLIELYDNFIQEIELRINSLSLMELCTKVAAQYDKPEDALKFLDRCEDRVRTSPVAFALHKITKGTIKLEKQHDVAGTKVILEELEEMFRQFDGISPVHGRFYCLQSKFYWGENNLVEYYKSALKFLGCPGTCPSDLTHEEQMKHAINLAIAALLADGIYNFGELLAHPVLLSLKRTKYEWLVGLMEAFNSGNVTEFEHLKSRWGQEEKLAKNEFKLRTKVILLAIMEMTFKRVATERQFTFKDVAEAAKLPEEQVEMYVMKAISKGLINGTIDQEAQKIYMKWVQPRVLDTSQIGTLMSRLDKWRKDLRKAETMMEAEAKIVESDFSLVSFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXW8</accession>
    <name>A0A1D2MXW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enhancer of mRNA-decapping protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000399">
        <property type="protein sequence ID" value="ODM97889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXW8"/>
    <dbReference type="STRING" id="48709.A0A1D2MXW8"/>
    <dbReference type="OrthoDB" id="10030313at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612:SF0">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="686" mass="74160" checksum="DB9C9505D0C27655" modified="2016-11-30" version="1">MSQQEKQKQTEKFVGCILSVKTKPGPFGDVQHIIGTVREIDVDSAEQAIVLDQAMSNGAMLPDGYVLLSSQIADLQVMGKANEIQANLKSAYSRSEAVKSQESSIIQEINQSEPTVRNSNSSNDHMKNFNSSFSNGAESIRPINGNHMHKMGVQPHVNNSSAALIHSITSAIADYTVRNNLSESDDSNGYLIAKPKPRKPDSGVAYNSSPQHKAVAQKISDGITNQISSKSSTNMGLSSNTAADDGNILVRTFGNLSTSSGVSLNGQALFNAVANSNKHSAVPAANIKKQNAPSPSKLSPQKPLMYDHKKLGVLSQFVSGENTSCQTYVTDENQLASATTPSGKSINNNHHEAKLSRGQGKATAAGRPRHGETFESMTKAEMAEEFDFDASNAQFEKLPVSCTKPTKVTKNPHFCSSDTTYLADRAVESIKLKETVTSVKQFVTDTGVVIPSVDLSTRSKILNLAHEAGLTHSRVVEVMGRAVVQATIPLLGDAYRLSPERAEDRPWVLVCAGPHWQGAIGIATARILASLGVHTCVYSPKEEVHLCAAEELLYNLTGEILTRNIGDLKGIHFDAVVMCVDDHLQRNLNVGPYTRWLNSCPVVFVDPPLISSYRQPIDAICSGTQKGRRIVIVSPVLPIAYPSDPSVKLFLVNLGIPQNIFERNDVLYKSPFGDKLVIQIFSAGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY74</accession>
    <name>A0A1D2MY74_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibrous sheath-interacting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000399">
        <property type="protein sequence ID" value="ODM97891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY74"/>
    <dbReference type="STRING" id="48709.A0A1D2MY74"/>
    <dbReference type="OrthoDB" id="8197715at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038891">
        <property type="entry name" value="FSIP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47315">
        <property type="entry name" value="FIBROUS SHEATH INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47315:SF3">
        <property type="entry name" value="FIBROUS SHEATH-INTERACTING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="761" mass="89026" checksum="99DD9B21C3576357" modified="2016-11-30" version="1">MQVLLIMNDSSQAEKEESKPSIKCRHRVRRQCSTRSAYIDANKVYSHQPKLHNIASCIDETRGAANSVGDTFSQEFSEAPEDPLVDCNANQNITANYPKLKARRRLHRQKRNSNANDSSRTGEGKSSNVQDDFDRSGYDEEKERYARQKQYFGSELNFRSGEFKYWQDVEKVWRNEEGNPRLRFERILRHSKRQARYHSVVDQLCDIKFNSHNFVMKSDPNDDRGYSASEDEDLEYEQRGGNTAGNEADIEDNVVPPSTPTPDMLSMKLRMKPTIALPTTPCRLATSREEYKKNGTNLRNTSPGQRLSQRPRSAIETITDTIERPEGSVPPLALPHWHSMPMDKKIPSVPAPKGLLYYSPGKLSTNLHREPRVYSLTDPHNRERVVGSPYTALHDIHAKDYISRPQTRRLLHSQGLINSNDEIMYSLREFNRYRDYLRTLYADDVNSHVHFADELWKCERTQMRSIVKEICQTVGKGAALQKRLNNGRLYRRKVEDYQIARLLRKQKQTEARLIAVAKEKEQINTERVVRSIERNRLQRAKLQSLQRARKEATAQTFHQSAIKGIRSFERKNMDMQLVKQTQESFLMEWIDSKIDHSKARVERERCIQMSSKEGLKMKAAKRQRRVESYRMHLPDLMEKRKSEEDRKWNLAKKYFYIWLERTRKQVAALNKDPSHESAWIHGMVSNTLEETVEYLRFQTGKYEKLDDFIANIVHLKEAIARQIAIEEAEEEMEMLKQQQEQHKMLDEVETKDNPQPHGNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYF6</accession>
    <name>A0A1D2MYF6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Solute carrier family 46 member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_08596</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000383">
        <property type="protein sequence ID" value="ODM98083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYF6"/>
    <dbReference type="OMA" id="VVMFLYM"/>
    <dbReference type="OrthoDB" id="419734at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM98083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="537" mass="59849" checksum="DB29A361D446D8F4" modified="2016-11-30" version="1" fragment="single">IWKIVVVLSFSMNHQNTNSSTSIENNGNGSSGFIDDTAELNDSDDSSQSSSSSNEEDDDSFADNRQIINNNDSHQPEDISCGELLKSITIEPMMFAHMFGMSCTSVILQNLYIQRICRISLNYTDTVCDDLADNPEIEHHIDELASKFVMYRSFIEAGFPIIVSLFLGPWTDIHGCKWPMILPMFGYFLSAMSYVMFSFVDGAPPEALLVSSIPVAACGGLVSIVMSAFSFTSKSTTVDSRSFRVAMVEASWFLGGPLGTLSGGVIYKYGGFTTVFIVSASLFLIAFLYGYIVIKEELPEIEDRDGRNCCTDMFNVEAVKEMFATVFFKRSGLQRRWLLLMLLTISLRIFALFGYIQNMYLYTNHQFGWAVKEYTAYSVSDSFMAISGGYVMIMTCMKIFKLPDAIIGIMSTVGIIVSQFVFAFAASGWMIYLGASLQMFAGLISIVLRSMISKVVAKEEIARVFTFLACGEATMPIVGVPIYSYIFRHTLDTFPGAMFMVSAGTYMFIISSFIYLYFSMRNANNHIQMDDPTETEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ63</accession>
    <name>A0A1D2MZ63_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000363">
        <property type="protein sequence ID" value="ODM98336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ63"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="227" mass="26378" checksum="976A4B4B28EB09C2" modified="2016-11-30" version="1">MANHPHFTELSRIFCFSSLQRITPPFLIACTPLLLIQRWTLSHPMFFNRSSQERTLPLQPQFVNNGTQWSTKYWRTVNLEYHDWVLNKAYFNMTFQGLPSMTCLRLIRKLRRLSIGGRKLRLFCPSSRPPIGARAGLPHRLFLDYLVTGLALEMVSLPLLNLGTYIHRISPWWTGVTIPLFGVTLYFLATQSFRTMDMIRMKGIGLAHLHLLESVSIEFPPSRLYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N011</accession>
    <name>A0A1D2N011_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000341">
        <property type="protein sequence ID" value="ODM98570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N011"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904817" evidence="2">
        <location>
            <begin position="24"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="22565" checksum="C7E101CC73D56892" modified="2016-11-30" version="1">MKFGKFILIVGLSISSLAILVSGKPSSRRLKNQRNKETEVDITKNDDSGSATSAIPPIGSLISSNVSAASVQDSDLTLPTPGLKPKKLKKSHRLKHRRFGHHHKKHNRRSHNHRGIPFRRRHHNNSTKQDDPTESVTTLDASSSILNSEPADLPSLKLLRSGRSGHRKFKRHHHHHHHRPQSKRLGKKAAKEQLAGENKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N034</accession>
    <name>A0A1D2N034_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FIT family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08259</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000356">
        <property type="protein sequence ID" value="ODM98424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N034"/>
    <dbReference type="STRING" id="48709.A0A1D2N034"/>
    <dbReference type="OMA" id="TYRFWYL"/>
    <dbReference type="OrthoDB" id="5579088at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034389">
        <property type="term" value="P:lipid droplet organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03230">
        <property type="entry name" value="FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046401">
        <property type="entry name" value="FITM1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="354"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="45640" checksum="0031FE04E011D745" modified="2016-11-30" version="1">MQATAAKKRPSVGSIPPSAQTRNSFVDKGRWEKTKGTKPVQDPATVGEISTKVLVHFCRKVLFVEPRYRLTAYAVLLFFASLVADYMPFPKTYFAYSDNFPNQYFVKFSWGWTFVTTGLFMYLTTAVYCCGNRQQILRHFVRLAIGTLVWFTWTNLFSMIETSTGQCLTKEAALYSVKSRRNCLTKGGKWTSFDISGHAFLLIWCVFFITEEARAIIGWDSIKDFIRNEEHNRGSTAKYGPAAADTFAETPLKTLTDEEFEALKLNYTKHDVAAKIVLVGLTFLTLLWDLMILATALYFHVMIEKVIAGLIATIMWFAIYRGFYSLEISPGLPGSGLFKYSEVKPTAIVTATPKPSTSLGKGSSTAKANKPASLPDDVPKFMGMPLYALRKRKDDLEMDDLDLATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0M7</accession>
    <name>A0A1D2N0M7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000316">
        <property type="protein sequence ID" value="ODM98857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0M7"/>
    <dbReference type="STRING" id="48709.A0A1D2N0M7"/>
    <dbReference type="OrthoDB" id="7451754at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031437">
        <property type="entry name" value="Ig_TMEM132_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026307">
        <property type="entry name" value="TMEM132"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13388">
        <property type="entry name" value="DETONATOR, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13388:SF11">
        <property type="entry name" value="DETONATOR, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16070">
        <property type="entry name" value="Ig_TMEM132_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Transmembrane protein family 132 fourth" evidence="1">
        <location>
            <begin position="94"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="350" mass="39702" checksum="ED5D9BE6C29A6D8C" modified="2016-11-30" version="1">MVPYNCSEIYKHTKPVLVFVHGSNEGEEVFNWILEASEEAGDDLDRGRVVWILRYVIQPSADSSWMKKDPFSNFGDERHKLTTRLEIQKDDIQAVLPIAKSWEVVNAAVLNGKQVSRPMKIFIVSRAGQVADVTLQASCRSLDESVLKVSSSCTSVYVDGSESRGSTNATIIIKYGTYEGAAEFTVWMPEFPLDIQLSDARLNQIKGWRVPNGLREYVCFFKFLNVFLLVTGVDLDHDDVDYFPLGSICFQSFPLWYFDDDVTMYHKCIKDILEAHKSLILKITGGKKRRWRKIKPETFSPFQSNRNLAVGIDKRDLLPVCGTVPKGVLRKKAVAMEKMHESSFLDVNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N147</accession>
    <name>A0A1D2N147_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000308">
        <property type="protein sequence ID" value="ODM98950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N147"/>
    <dbReference type="STRING" id="48709.A0A1D2N147"/>
    <dbReference type="OMA" id="RITHEFN"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="401" mass="45547" checksum="F4D56CF7383450F1" modified="2016-11-30" version="1">MDRITHEFNFGSADENANSMDSEAIMKEIRHLYNAKEVGLREASKSIRGSAPIMKSPQQKITVLLAGSHYAAKEKFLNLYFNGAQEEDELTSKVNNYENHDRIFITNGIRPRKCLTGVKVLDCCPHLAKLGYVPGLKDYLTTEIAAEKTKSLVSFIVAPENVDTLHHEVASDMNNIHVILPVMIEKPMKALVEAADLVFIFFDPTGRTPPSQILKPFDDLWEYHHHKMHLLLAKANEIPLETTLTQIVQQVWRHPQIQRLGCTPKVFCPDLSGRVLGEDEQLWNIIKEDANKCTEQALHQLGKDATYIENELTDQLEKKRKSFGILKVALVCFWVGILCACHFDFLSVNSGLFVATFCSLSPVFLSRLDKELLKRRIRFAHNALCWKESIQKPVPKLSKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1H6</accession>
    <name>A0A1D2N1H6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000302">
        <property type="protein sequence ID" value="ODM99061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1H6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="6874" checksum="311EDE18928CA951" modified="2016-11-30" version="1">MSSKDTSGKGMGGGSSWGAGSGGGSGGCPWGSGGGGGSGQKCPKTGAVGPQSSCPGCKSTGSSQSSGGGSGKSAWGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1V3</accession>
    <name>A0A1D2N1V3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000289">
        <property type="protein sequence ID" value="ODM99277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1V3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="27020" checksum="09BA5D01286C6952" modified="2016-11-30" version="1">MSKAASTAYSDDDDVIVIENTNYKFQQVYTATWEIREFKKYFQIHLENSSKDGTELCPIRNYLIETGEKIGLPCKWIAGLYIHPLDEDANNNDPKVDSNFNIRISMRLVDAPIDVPGVFSNCRFITRVREVQLQKEYTLEKVLEWSKWHTLFDMDSTFCCTFEQHVYRAPLDWGLTADALDFVVEPRLGKKLSEKERRLSKQINQTCIMHDYFLFSNCNYNHSTYSKSVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1W7</accession>
    <name>A0A1D2N1W7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CD109 antigen</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07797</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000314">
        <property type="protein sequence ID" value="ODM98885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N1W7"/>
    <dbReference type="OMA" id="IDSAFYT"/>
    <dbReference type="OrthoDB" id="6359008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02891">
        <property type="entry name" value="A2M_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.690">
        <property type="entry name" value="Alpha-macroglobulin, receptor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009048">
        <property type="entry name" value="A-macroglobulin_rcpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036595">
        <property type="entry name" value="A-macroglobulin_rcpt-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047565">
        <property type="entry name" value="Alpha-macroglob_thiol-ester_cl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041555">
        <property type="entry name" value="MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF172">
        <property type="entry name" value="LD23292P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07677">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17791">
        <property type="entry name" value="MG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01361">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01419">
        <property type="entry name" value="Thiol-ester_cl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49410">
        <property type="entry name" value="Alpha-macroglobulin receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1534"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-2-macroglobulin bait region" evidence="4">
        <location>
            <begin position="444"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-2-macroglobulin" evidence="5">
        <location>
            <begin position="717"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-macroglobulin receptor-binding" evidence="6">
        <location>
            <begin position="1413"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="664"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="676"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM98885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1562" mass="177982" checksum="7DFAACD3005DBB04" modified="2016-11-30" version="1">MIRYFVVASKMVRPGQVFRVAVTLFQGQVHLQEIEVRASLLRNGVDIGSDTKICQPNMPETLMIRVPRTSIDGDYRLRVEGNDNGLVGGTAFLNETQLTFSSRSMTIFIQTDKPVYMQGQTVRFRAIPINTALKAFDDAVDVFMLDPRGNVVRRWLSRTVRKEDWIYSTYNLGTILFSPQALQQIEMKQFFVEEYYQPRFEVNVTMPAFAFDTESVLRGEIVANFTHGGPVRGNLSVTAIIRPILVAGRPAQATRNPFYEQYPQLHIYVPDFKGHFEFQFPMWEIERSVAVLDNIEVEVSAEVGDHYWDEVQTGYSKVRIFNSSLALEFLGGSPQVFKPNMPFVCYLTISYHDGSPLLFERLLTSNLEIQPEIIMRGGGRRRLGTRHIQMLRSQPGTWQVTIDLKQELGAGPERSRQITNLLNDETATAEVMAVAHFSPKNRHIRVSSSTDAPKVGEYIIFHVRGNFYMDRFSYLIMSKGVILLSGSEVMDATIRTFAISVAPQMAPAATIVVYHISRYGDVVADSMNFPVNGISRNNFTVEINNKKEKTNNIVEIIIRGEPGAYVGLSGIDAAFFTMQAGNDISYGEVLSKMSTFDDDSNGTTLMHRWISRDGLPDEIAYFPVHTFGIDANRTFEYSGLVVFSDIPLPRRDDVCNETAGWYSCLTGGCYFIDKKCDLQRDCADGTDESNCPRFNRTELVDFKLHRFNRMQRLYENVWLWKDLNIGPHGYNIFSLPVPERPALWMVSSIGVSPTSGFGLLRKPIIYSGVRPLFMNVEMPEVCRQGEQVGIRVTVFNYMMKDIEVMVVLADSPNYKFIHVESYGIVQSYKPRTSVGEHQHLIWMRAGDSVQVHLPIVATVLGEIEINIRLIGQIARDEVTRKLRIEPDGVPQFRHTAVLLDLSSRSFFLQYMHINVTESPIIPYDFDRYYVYSSNLAEISVVGDVVGPAFPQMPVNATSLLKKPMDSAEQNMFSFASNFYTLLYLRLTNQRNKTIYRDAFHHLNALYLRQLSFQNEDGSFSHFRSDWYAEAISYTTFPILKVFLMPLLLIYRNNSAPSVWVTSYCARCSLKQVSMNGKISCTLIITAVHWLLDYQTEEGSFYEVSQYSNRRLNDTTFEDGNLRTPNITLTAHVLISLHVVKDLPGVIGPRVAVARQKAVNYLEIQVDQLRFDADPYQIAVVAYALMITKSSKADAAFIKLSAAKQQSDDLEYWGKERVPTPDYKLENNKPFLLPRLPYKYDSSNIETTAYALMIYVARQEVVLMQRIVRWLNSQRLYDGGWASTQDSAAAMKALIDFTIRSNIRNVTDLTVTIEAVAIPDKVTTFHINADHLSTRQVLKISDAYGSVKVQVKGAGYALLQMQAQYGVDRDRFITDPPVRAFSLVPEARYTGRNASLIDYKICQRWTYLEESERSGMSVLEVTVPTGYFLHQKKLDEYVKYGAVSTLRRARYFAEKVVFYFDYLEINPTCVNFTLQRWFPVANMTRYLSVRVYDYYAPERFNETIFEALDLYMLDICQVCGSYQCPYCPVFAGGSILNPSMTVIFLSMILFVFTSYCTSASTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N218</accession>
    <name>A0A1D2N218_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucan endo-1,3-beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000290">
        <property type="protein sequence ID" value="ODM99261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N218"/>
    <dbReference type="OMA" id="GQLHCQG"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013">
        <property type="entry name" value="THAUMATIN FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013:SF2">
        <property type="entry name" value="THAUMATIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904902" evidence="2">
        <location>
            <begin position="21"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="29"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="78"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="145"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="150"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="28676" checksum="18839C65C4878852" modified="2016-11-30" version="1">MRTCSIVLLCALALPALIAGRKIKFTNHCNQAVWVSPLTNAEGPVLGAGVVKLTQEGSHTYQIPDAGWGGRFWPKMGCNANGQACDVGQSMPPCKPAGCDPPAETKVEFFFPPIGNGQDVWYDISLVDGYSISAAIIPSKIQGTCTRTRCAMKLADCPVEREVGDLRVIQGGKTVQCLSPCKKWNYPPPFGLGRPETQGNGQWYCCPTPPITPQQCRNNLVVNTEYVKLVHRDCPTAYSYSYDDEAGLHNCPNNVDFEVNFCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N354</accession>
    <name>A0A1D2N354_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Disintegrin and metalloproteinase domain-containing protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06958</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000259">
        <property type="protein sequence ID" value="ODM99717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N354"/>
    <dbReference type="STRING" id="48709.A0A1D2N354"/>
    <dbReference type="OMA" id="NCSKNAY"/>
    <dbReference type="OrthoDB" id="5951731at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000001">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006586">
        <property type="entry name" value="ADAM_Cys-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08516">
        <property type="entry name" value="ADAM_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00608">
        <property type="entry name" value="ACR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0401">Integrin</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="6">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="5">
        <location>
            <begin position="114"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="350" mass="37692" checksum="1B170B1C3660A159" modified="2016-11-30" version="1">MSAVEFENGVVGKAMQGPICSYKYSGGVNSDFKNNVIGVVATTVAHELGHNFGLSHDTESCTCPSPNNRCIMAASASSNRTMHWSSCSLKDFAYAFDHGMDYCLRNKPESLYDGPTCGNGFTEPGEECDCGLAEHCENPCCDASTCLMHHNATCASGTCCDMETCHVKAGGTVCREGTKLCDLPEYCTGDSEFCPDDVKKMDGLTCETPSGKSYCYNGECRTHTDQCRLLWGPSGNNSNDLCYQKNANGSRHAHCGYNLTTEKYAKCDSEDVKCGILHCQMNSEKLEFGYESVSILASFFVNAGGKIHPCRSVIVDFGLSDINPGMVPDGAKCGDNKTAIADLHGKHVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3U3</accession>
    <name>A0A1D2N3U3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_06752</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000246">
        <property type="protein sequence ID" value="ODM99932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3U3"/>
    <dbReference type="STRING" id="48709.A0A1D2N3U3"/>
    <dbReference type="OMA" id="PEDTMMA"/>
    <dbReference type="OrthoDB" id="69646at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021910">
        <property type="entry name" value="NGX6/PGAP6/MYMK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14319">
        <property type="entry name" value="FIVE-SPAN TRANSMEMBRANE PROTEIN M83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14319:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12036">
        <property type="entry name" value="DUF3522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="718"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="748"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8 9">
        <location>
            <begin position="553"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="823" mass="91989" checksum="724245CDF7962F54" modified="2016-11-30" version="1">MVVLHVVPVTSILPQVSQEGLLRPYRSYADVTLFHYYVPNEVSRATFEFAAFMDSRNCPVRDVYIYLQHGSYPVMAPDNATFPENLYTGRTSMFNLVLRSSYQPHDATVFPVYNPLPGSWFAAAYLPDWDQHVQQEGIGHKCQYSLGSVALWSQVSNVETIPVKTTTRLSSLEHFTYFKFYIPAGIWEFKLEINGCHFHSSHRFPEMETSGNTTGSGGGNQHSPIPCIRNVFLRPRALPRFKSDGTMTTITDLSDSELSHTERLPFTDSYYYILVVAETKVSYNISVFVKDCPVQILGRSFIQQFAGIHTAANLKDQAVRINMTTTVTTKVVSKEQQHGIDDDDDSTPFSCDCVPMFRLTRIKHAQDFSDTFLLEGREWFTTWLAVTDTMAVGAAWEILPYVDIGGTLNVGIHLDALLLNATTQVLHVFACIRKSRPPEPLCCAATPGNISTCCQTGLDLHVSSKNKSLFGDTILIPYPEPDTWYISFTTVCFSGENVVPCAVEEALLSLDIRTQPCVLTKPTTSQSESSIMPCGPYGVCQEIHKGQFFYTACRCIGGYRGWACTDDSQATPEFILLSATLLLTLSNLFFIPAIFLALKRRMFTQGLIYSVTMISSTLYHACDQDIYGYCLTRYAVLQFCDFFCSILAFWVTLIALAKSPPKYDSSLYMLGAVVIAIGVEYNRTGLMVFVFPFALGISIPISVWSYRSIKNRSIIVPPLSNVLLFLPGVVLGAAGLVLFAFVETEDNYRYTHSAWHVIIALSLVYLLPKQQKRYNFEPISAENEANSTAAELSAVNNDNQTTSASPVFFITSDLDHLVQEQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N478</accession>
    <name>A0A1D2N478_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hamartin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000234">
        <property type="protein sequence ID" value="ODN00087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N478"/>
    <dbReference type="STRING" id="48709.A0A1D2N478"/>
    <dbReference type="OrthoDB" id="6022054at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="325"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="514"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="674" mass="75087" checksum="CAE9771D6F74604E" modified="2016-11-30" version="1" fragment="single">VQLEQLQSTHVHAENLTTPAFGVPVPHLNQSVEQGTRKVAIVQPHTNVADGVVTAAVSAELLVRSDSTQESEKSTGGPLTPLPGHNSSATGPGLIDPDLSLITLDEEPVGLDECSNRTCVSGGLHMADHKSMVAFARKVNRLRYHSHCIAGSDFQTSLGPSPGTSPSSTSSSSVINARSRFMKRSMSCPDIKKPIIEDKDGKTPKLPEVSEVNSGLEDKADGASAEVEQENAPKEPEHPYEHLFQKILPSVMSPLESRTLPSPHLLLDLCLMKAANLHPPKSKSEEINVLKGHIELLHGQLLFERHRREAHAHRNRRLALKCRKTVTLEEQNNTMGQKIHNLEKEIASLKKEVTIQRNVGLVKERELLNTIEGLEGKLERHKKDISILIQDKSHLESKFSLLQEEFSILQKESDQKKADFFSLENEVKNCQKYIERNKELKTAYEARLKEILVLGELLRRYKEITTPPSECGYLVEQMEACRQTHDEEIRGLRTLLETVMSQQEASNGTISDLKKRLEKREAIIELQRKDMQEKEQEHHLQLHALETKYESIKATNNRLELEILSLQHQISLKTVNTRPTRGRITSSSPSNNGEVSPAGNSNHSDVDSAASAGGFQMSPERNMCIFGSPQFDPPSEEMKDLQAVLDKEYAGAIAAASSRRRNSSPLTHSRGDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N508</accession>
    <name>A0A1D2N508_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000238">
        <property type="protein sequence ID" value="ODN00026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N508"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905041" evidence="1">
        <location>
            <begin position="25"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="343" mass="39102" checksum="CB01936C818CCA90" modified="2016-11-30" version="1">MNLQKLLACTVAVFLIVFSSPTSGAKPGRPLHLREPLEELSTKLQAVIKNFNIFKLISAIGEIGLGCLLPPESELATFTNLIPIDVNYLSLLAKSEPQSINPIFWFTQKQLAEYCESPDFTLIHEHLWLNDTSTRDLVEFFYYNEYPKIYETIRDLYYENSCPSELIATLPTGPGQPKTNTYPLSSNLRDEIGKSKKKSFIKQEEGDPCSLLEILKKIESTGLFELLYFIESFVYQFSTQPSLHFMVAKIQEDVKGVSFRKFRLMQPVRKLFDGLHQSIVSSPNIEVLLLQLKELTGIDLIATNIVETVATILETVVWGNSDSIPPYNPNAVYRYEEEYVVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N545</accession>
    <name>A0A1D2N545_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dynein assembly factor with WDR repeat domains 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06617</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N545"/>
    <dbReference type="STRING" id="48709.A0A1D2N545"/>
    <dbReference type="OMA" id="RICRIIN"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="303"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="351"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="394"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="436"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="493" mass="55057" checksum="9F9078C01574BA69" modified="2016-11-30" version="1">MKDITRRDAHDPRRYKSLKSSRQKPFKDVILKFIHLRYYPPGLILQYLDCQGKLKEKVIELLELSYTSNISRFSNEVLKAEPLLFSTKNHRTALVDALTKLKDRCLHDYAKRFVKQYAFFPHSCPVTNMCLSKDGKRCITTSNAENICSVWDLGGMRETALLQGHTKPITAISPSHFFDRALTGSEDGTVRVWELSSPSGLLPSSRCNQSSSTCQAELVVTKDKILCAEASSDFSMVASGCSDCSAYVHDLTNCIAMYRFSDVHSLEITNVQFDTSGNLLLTASVDGKAALFDLRSGNLISVLEGHKKEITNCTFDHLCQTVATCSLDSKVRLWDVRMLSSGTSTNVLYEFIENDDEIYSIHFDTRGKSLASGAKDGTLTAWDVKTGNLLFQIPNAHEGPIRTVRWSPNGALVMTASDDKTINLFHPDMATCIQTLSHHKGPVKNAAFCYSNEYLVTSGEDRSVVVYRLEKPLKNEPFVLSSINIRSSRLSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N614</accession>
    <name>A0A1D2N614_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000190">
        <property type="protein sequence ID" value="ODN00713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N614"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="403" mass="45578" checksum="F2C9E83C3AF42F57" modified="2016-11-30" version="1" fragment="single">EVDCVSQWDPFCNEETLYTPYVRIFQKGRSGAMLRDRGPGFIDVNGLEDIYVCTNGLVMLYYSKTKGNSDVLKGEIYEHGELHWAPHHCELYNPSCTALGIDQPKKTLLSILLIGHPQDYRRPALQMFVAPTYDQVYKNYVNLTSLIMISTDGECLMEKGVERARLRVRINEPPLPVPATGTTGTPPPPPERPPYFCQLDSQRKLGQVDVINLNKPYDKLFTTKKDKPMFEGNNDTVKATQVETGSLIVNRFRPSKVEPTYFYDKTAAASILEVADQVYAALINDRPMRFLGCLQYPDFSFEQEDILAKKRALLKDNSTGTPVDLDFEKTKPEATADWWKDDIVQPWVVPDPAVTPTPTVTRHAAYAEGWTAENYQVAYDKLMKPAIEGLDRQKNLAVPVQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6H2</accession>
    <name>A0A1D2N6H2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6H2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905114" evidence="2">
        <location>
            <begin position="27"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="46246" checksum="4099108812372190" modified="2016-11-30" version="1">MKLRTQKRSLLGIVLLHSFLLNYGVAADASIDPKGSKVIKPFLATNTSIYRISSYEATVFDAWDDCKNLTAGNNRFQLLIIESEAENSNIKSQLRKLDISSVWTAGRKAEDDSISWTRLDNDPVPMDMRIDISNSRKRRSFVQKPISKPDNGPPSERAVANKTVDPVPKCRRNLIEECKPPTCKVTLPECSIKTPNCTATSKPECSATRPDCSARCENCTVAVPPQCYAQPQNCTVKTPQCEVVETTECEIVTPPCTVEREPCQAHCPPPVVTCPDPEIKCNVKPVVKCDPPEVVCPKPTVVCTEAQVICSSPIVNCPAVITTCLPPDVTCPPPELDCPPPEVVCEKPDTDCKFGSTPEPCPEETTTTTEATTTTEAISSTKKPCPGCGCMLMKKSNKYKWDFEKCHFKHRFICEASKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6S4</accession>
    <name>A0A1D2N6S4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000181">
        <property type="protein sequence ID" value="ODN00932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6S4"/>
    <dbReference type="OMA" id="PRSHYPE"/>
    <dbReference type="OrthoDB" id="10617840at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17865" checksum="2BA8CCBEED6E3EFA" modified="2016-11-30" version="1">MFIMAVITIQFMTYFDTFHTQLMSACCRQIRQGCEEQMTLEELARRRQAFYISEASRSLQELEDRSTRVTTIYQDSAGLALGIYEIHVPRSHYPETVRSNRPPKPNVPPPPYPEELPPPTYDEYLKLSAATAAAGQTQQAGVPSVKNNSSSDDKQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6W4</accession>
    <name>A0A1D2N6W4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell surface A33 antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000177">
        <property type="protein sequence ID" value="ODN00987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6W4"/>
    <dbReference type="STRING" id="48709.A0A1D2N6W4"/>
    <dbReference type="OMA" id="HAYKYRD"/>
    <dbReference type="OrthoDB" id="10015491at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000437">
        <property type="entry name" value="Beat-IIIc, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905137" evidence="1">
        <location>
            <begin position="26"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="20"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="32676" checksum="968B064A6FD882DF" modified="2016-11-30" version="1">MDSAAHWRIIWTLLLLSNFPRLISSLKLTATIIPYYAILSRPVVLHCNFSLENDSLYALKWYKDGHEFFRFKPSDDPPVTIFPVAGVSVNTNNSDLTSLELDRATLLTRGTYRCEISADAPSFQTVYEEQYMRILALPVTGPSITGTLPWYNLGDNFSATCTVEKTFPSPQLTWFINDIQIDSNLCECMVSQTSEAGKAIDGTTFYTSKSQVKFQLEAHYFRDGSLTAECRAIFPKSNITLQDTIQSNIKAGLGLRHYAADLFSNSPKTQLGRYNVIILTSLSIANKFIPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Y4</accession>
    <name>A0A1D2N6Y4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Magnesium transporter NIPA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NIPA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000184">
        <property type="protein sequence ID" value="ODN00835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Y4"/>
    <dbReference type="STRING" id="48709.A0A1D2N6Y4"/>
    <dbReference type="OMA" id="STWMPWF"/>
    <dbReference type="OrthoDB" id="6428174at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF92">
        <property type="entry name" value="SPICHTHYIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="41594" checksum="E9B7D68F703E8771" modified="2016-11-30" version="1">MSLNETDYYEGSYNSTSLSSGSVLNGTTPTSFFNNTSSSDSVGISDGETVFTPAVGNWTDEDNTMMQITTTVYNETEQMHLDQLEQQQIIQFWIGVGLSISSSLFIGLSFIIKKKALIRLSKGGRRANQGGYGYLKDLLWWAGLLSMAVGEAANFMAYTFAPASLVSTLGVLSVLVTAILSSKYLNERLNFLGKVGCFLCTIGSTIIVIHAPMEKDIASMYDLQIKLTNLVFVFYVLITIVVSIILIYHFLPKLPDTSTYTLLIWIGVCSMIGSLSVMSVKGLGLAMMQTIGGVQNEMNNWLTWFCLLTLIACISVQMNFLNKAFVLEEKSTKAGEKKKWALRNLQKTNRLNKKKKKSKKFWRPGNNPSFSWDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N731</accession>
    <name>A0A1D2N731_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ras-related GTP-binding protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_05636</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Lysosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N731"/>
    <dbReference type="STRING" id="48709.A0A1D2N731"/>
    <dbReference type="OMA" id="NCRTFQE"/>
    <dbReference type="OrthoDB" id="26136at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019003">
        <property type="term" value="F:GDP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043200">
        <property type="term" value="P:response to amino acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11385">
        <property type="entry name" value="RagC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.190:FF:000001">
        <property type="entry name" value="Ras-related GTP-binding protein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000226">
        <property type="entry name" value="Ras-related GTP-binding protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039400">
        <property type="entry name" value="RagC/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0458">Lysosome</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN01051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="389" mass="43949" checksum="1C772BCF2B1617A7" modified="2016-11-30" version="1">MAAENGEDITVAVAQKNASEVTEETGSYPKDLSYGVYDCDPSSVDPNGTIISGIEQKPRIVLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKVVKEDISNSSFVQFHIWDFPGQIDFFDPTFDSENIFGGCGALIFVIDAQDDYMEALERLRHTVTRAYKINPRINFEVFIHKVDGLSEDYKMDTQRDIHQRATDDLYDAGFEQVHLSFHLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSAIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYGLMSGDELAPAFDRHSQASIRLNNGTVLHLREVNRFLALVCILRDDAMEKQGMIDYNFTMFRAGIQKVFEVRKSQNRKMAAISFTNENGEAAHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8X1</accession>
    <name>A0A1D2N8X1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Brefeldin A-inhibited guanine nucleotide-exchange protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000143">
        <property type="protein sequence ID" value="ODN01691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8X1"/>
    <dbReference type="STRING" id="48709.A0A1D2N8X1"/>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF344">
        <property type="entry name" value="BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HDS" evidence="2">
        <location>
            <begin position="345"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Sec7/BIG1-like C-terminal" evidence="3">
        <location>
            <begin position="721"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="739"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="739"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="987" mass="111325" checksum="B22F5A9DDC09DE1E" modified="2016-11-30" version="1">MSKNQFIKLNRAINGCEPLDEACLSTIYDEIDANYRRDAGTCEQMKWMASVEKSEEEILRTIKSILDSTSLLRSHFSLAKQLKHVKRMIKICGTSFLIALINALQSTNDTKLSDVCLDGLHSGIRVACILGLDNEREAYVQALAKLSVVALDEIRGKHINSKVVTTTTSSLTMTENGVTKTVVTTTTEMKCRSVDVILTLLDVGIAEGNHLGGSWLHILKFISQLLSTPLLAESRNSSRSSSPVPPPTGGGGSGWAAWAGSLRESLEKKLWDPSTTVLHPSVKESIASSVEKVFKRSELLTGDAMTEFFQALCQVVADYFCHLACSSKEEISTIAIDSIQKLVLKLLKKETLNGYRFQNHYFSPFKVIITNTRSQSTREAVLGFVETVISLYGDLLLSGWIAILSILVTNMLNHSDKDAADSFRVLQHIVDKCQKGEVNLRNSFGSIVKALIDIASNIAPTLEMSEQAFRLLTQMAEVPYRQPQLLMEENDGSRRYRVWSRGWKPILSELSNIFCNTNNSVNGNASCKLSNEGKLPSWDIKTKALITLFEVIKTYGSSFEKEWWNSVFEILFNIFSCMKSHEKQDLLATQTQLPSASSPSSSDGSYKYFYCYYYVQFAIFDVYTQYSDATGSYVFDELLKHLQWCICQDHEQIALSGVSCLQQLVVALGKRFSENQWDSILNVFQTICQPSGITQNNNLEGKASSNKDEIIPRQAPAIRAVIQLELLKIVERVIFSGSNRKSSSNSTDNADENATKSNSSTNEINPFLTSYQISIIVEILNRSHEIAKERCVIDTNNYEQESERKIEPPNFIPHETLSLQIYWRVLFSVFSRTEWSQSKLGISNEALWEIIKQSCIRSCGYFITIQLRDHRDAWADLLCYVMSNILELPKSHFEDMTSHLYPYFCDMLEVDLDSRICDKLREYLIQLGRDYAITHTKLKIEERNEDGAFENDSQFSAVPKTCNTSAQNQLFQPTFSEGYVNHSKDCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA97</accession>
    <name>A0A1D2NA97_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000122">
        <property type="protein sequence ID" value="ODN02171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA97"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905284" evidence="2">
        <location>
            <begin position="29"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="149" mass="17266" checksum="EBCFCDE4C5FAEE9E" modified="2016-11-30" version="1">MIRQVRSSRLAIIVTIFVLLYLTDCANSYSGQRVLWLYVLPQSQLYHHDRIPKVVEPAPEYITSELDSVQSYSRIRRFNEFHDHSQSQPLYHSRVITPLFITEYGSDSWQARGNAEPVYYENMMTTMGNRKEDDDSSGGSTEVGVENLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAM6</accession>
    <name>A0A1D2NAM6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000124">
        <property type="protein sequence ID" value="ODN02125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAM6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905300" evidence="1">
        <location>
            <begin position="22"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="8507" checksum="9812C0B8CA90649B" modified="2016-11-30" version="1">MKNAIAFTILLVFAFICIAYAMDPRHTAWNGCNCQCGGERGEIVGTVLVKELHSLQDRNMFQHFMDKKMDINGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAN4</accession>
    <name>A0A1D2NAN4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">L-lactate dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>(S)-lactate + NAD(+) = pyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23444"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDH/MDH superfamily. LDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.27" evidence="3 9"/>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAN4"/>
    <dbReference type="STRING" id="48709.A0A1D2NAN4"/>
    <dbReference type="OMA" id="EGQYGHK"/>
    <dbReference type="OrthoDB" id="5405561at2759"/>
    <dbReference type="UniPathway" id="UPA00554">
        <property type="reaction ID" value="UER00611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006089">
        <property type="term" value="P:lactate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05293">
        <property type="entry name" value="LDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000018">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00488">
        <property type="entry name" value="Lactate_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011304">
        <property type="entry name" value="L-lactate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018177">
        <property type="entry name" value="L-lactate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01771">
        <property type="entry name" value="L-LDH-NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000824">
        <property type="entry name" value="PRK00066.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128">
        <property type="entry name" value="L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+))"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128:SF16">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00064">
        <property type="entry name" value="L_LDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="10">
        <location>
            <begin position="24"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="165"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="29"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="138"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="344" mass="37170" checksum="79F4FE25D53CFE5B" modified="2016-11-30" version="1">MTSEGVSKVLFTPIVEESVSSRSKVTVVGVGQVGMACAYSILNQNIANEIALYDVVADKVKGEMMDLQHGLVFCKPVKISAGTDFEVTSGSRVIIVTAGARQREGESRLDLVQRNTDIFKNIIPPLVKNSPDALLLIVSNPVDILTFVAWKLSGLPKNRVIGSGTNLDSSRFRFLMSEKLHVAPASLHGYIIGEHGDTSVATTSDIPYKVPVWSGVNVAGVRLLDIYPNLVDESNPEKWADLHMQVVNSAYEIIKLKGYTNLAIGLSVASITKALLGNTRAVKPVSTLVKGFYGIQDEVYLSLPCVLGSQGVTSVVNLTLNAQETDQLVKSAQKLQNVQSQIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB20</accession>
    <name>A0A1D2NB20_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Mannanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_04225</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000111">
        <property type="protein sequence ID" value="ODN02454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NB20"/>
    <dbReference type="OMA" id="EAFPYML"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000050">
        <property type="entry name" value="Beta-mannosidase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000060">
        <property type="entry name" value="Probable beta-mannosidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0458">Lysosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905314" description="beta-mannosidase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="15">
        <location>
            <begin position="53"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="14">
        <location>
            <begin position="817"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="15">
        <location>
            <begin position="1074"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="13">
        <location>
            <begin position="1307"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="14">
        <location>
            <begin position="1821"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="908"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="915"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN02454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1920" mass="219175" checksum="BAC25C21E2B15148" modified="2016-11-30" version="1">MKTIAFTIAIICTLEIVSEVSAAEKYISGIERIILNADRTANVWTASGRNASNGNEISVGASVPGGIYSDLEDGGVLRSAVYREYNDLETRWVGRTNWTYSRTFTATSSILEKAEVVLVCEGLDTIAQVFINDLLVGKSENMFVRYIFDIKSTLRVGENTLRVSFQSPVEYAQAKFREHNETYGYQVLPVSLAPAFRGENQAQMIRKMQSSFSWDWGYNGAIIRDVMIFSTPSKPVPDETAATQWNVTARIYYDSVSDSEATLTFHRVDSMGLAKTTNLKKGMGQSVDISLTESGAKTLLWWPNGYGNQNLYWYNVSLASANSTEISTNMLRFGFRTVELVQDFVDKANKQKGREFYFKVNGVQMYSKGSNAIPLHVLPERITEAQTEWLLRAAKMSHQNILRTWGGGTYETEWFYDYADEYGIFIWEDFMFACAMYPATPEYLEIVRQEVDTQVKRLQYRTSLVMWAANNENEAALRHDWYGSGWNFELYKGDYIKLYIDTIKTLTEELDPSRKFISSSPTNGIKSEEEGWVAQDPYDLRYGDIHFYNYVSDNWDYNMFLRTRYASEYGYQSFPHYETLAEVADDITTWTWDSPMMDHRQHHPGGQKEIRDLIQMHFPFPENYDSTEAFPYMLYMAQLSQIMGQKTQTEFYRRLMDKMDENGTGHNMGALYWQLNDIWEGCSWASVEAKGRWKLQMYYALKFFAPILASPYRDANGDVVVELISDNALDRGFTGELNVKIVRLNSFTPVYEETVSVTAEFLKSKEVFRINKADLEGLDCASDPNLNSANPCVVYLTLPGTPDNFLFLQYPTNKQALVNPNLKITTVDMINENTFEFTVTSDAVAPFVFFTASEDHRGYFSDNGFVLTTNEKTIQYYSQDGITDVLQFMNQLKIMSLYDVTQIKETPATSQAPITTTSEDLTTTPAETTTTPVSTTAASADKTLLQTVTVLMCAFIMLIQGRLTLTRLISLHWDIFIVPLVPGPSGTSRFTHNAKKIKVENDLGIAEKTRSHIPVYSITKMYLAALAIITTLTFNPKLATANSGGVQRLSLDAKRHTNIWSVYGYNASTNTAIRISANVPGGIYSDLEETGTLKSPIYHEYNDLQSRWVGRVNWTFSRNFTVDSALLEKKSVILVCEGLDTVSKVYINDDLVGQSQNMFARYTFDIKHALKIGINKIRIEFQSPVEYAATMHRKHEEAYGYTVDPPAVVPAFRGENKVQMIRKMQSSFSWDWVSQVLTFFPLQVHPIQALAFGYNGCAIIRDVMIFNTPSKPVPDETSSTQWNVTARVYYDCDTEGESAILSFWRQHSSGTNRDVKLGKGEGVSKTHLWWPNGYGKQNLYSYEVSLTNDNGDSSSRQLRLGFRTVELVEDYVDPSVTSKGREFYFRVNGVNMYSKGSNSIPLHVLPERVTYSQTEWLLRSAKLSHQNMIRIWGGGVYESNWFYDLADEYGILIWQDFMFACALYPATDAFRDIVRQEVNTQVKRLQHRASLAMWAVYTKYMFSLHPGNNENEGALRGHCVHFKLIGLWGGASWNHQKGDYVKMYIDTIKVLVEKLDPSRRYIPSSPTNGIKTEEEGWVANNPGDLKYGDIHAYNYYGDNWDWSIFTRGRYSSEYGYQSFPHYETLAEVADDIKTWTFDSAMMEHRQRHPGGNYELSNMVRNHFPAPMNLNSVEAFPYMLYMVQLSQAMAQKTQTEFYRRLVDKLDESGTGHNMGALYWQLNDIWQGCSWAGVEINGRWKIFQYYAVNFFSPVLASPYRERNGDVVIELISDSQKTFSGLLRVQIFKLNRLMPSLFVFLTLPGAPDNFLFLQYPTNKQALLDPSLEISSVYQDSDGKTIRFMISTKAVAPFVFLTITDEHKGYFSDNGFILTTPQKEMTYYSEKGMSAQQFTESLKIMSLFDVTAVAGETVTGRKRHNMWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB55</accession>
    <name>A0A1D2NB55_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB55"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="57245" checksum="929DDBF23B7DE3CD" modified="2016-11-30" version="1">MVTADQSTSTVVSSNEHHHMSHYSSASVCSYYQSAVTTTKGMPTSVPYLDYNNHSHGMSAAAAAAAQYAQHAQQQHRVATAAVASASSFRATPHHHHAKVINPTQAVAYQQAYHQYQQYMHHHGMVHSHQHHPHPQNAPVVHQRMIGMPIMTNGAATVTQPHQQPRLVPFVNRTGPPMQQPQHLHHHHHHGYSNAQMMPTASYPHHHHQPVQQTQMDATAQLPNFVDASNNCSSKPCLASQPTKPVENGKSQYPSVPYVPNVFKGTVKDVNSKSRPDKPAKVRRTKASRDQQVEIGQGSKSEPRVKDQGSQFPEDFTPVVYTDQCDCARQQAWSYPVTSCNCPRMAINPAKPPPGFEHLMQSTFPIEQYDPSILGNLMRAQLCHEAMSFDGIPVCCEGVPLASLDEESDEEFLEIQVNADELQQDDVKEWSMLHSAIRQSLDDWTEELQTRQKIKEVLCKVDLQTIFVKNCDSSSSEEIVSEEESSDSSDALSELEHVLCPLPFNEIPVQVQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBQ1</accession>
    <name>A0A1D2NBQ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Mucolipin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_04006</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBQ1"/>
    <dbReference type="STRING" id="48709.A0A1D2NBQ1"/>
    <dbReference type="OMA" id="PMSVPHN"/>
    <dbReference type="OrthoDB" id="263481at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072345">
        <property type="term" value="F:NAADP-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21050">
        <property type="entry name" value="ELD_TRPML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000033">
        <property type="entry name" value="Mucolipin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049134">
        <property type="entry name" value="MCLN_ECD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039031">
        <property type="entry name" value="Mucolipin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127">
        <property type="entry name" value="MUCOLIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127:SF7">
        <property type="entry name" value="SD02261P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21381">
        <property type="entry name" value="MCLN_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="567"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Mucolipin extracytosolic" evidence="16">
        <location>
            <begin position="160"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="15">
        <location>
            <begin position="462"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="623"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="673"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="623"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="673"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF21381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN02679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="703" mass="80847" checksum="3A69DA513D4BFD39" modified="2016-11-30" version="1">MRKVEERDLTAQVTTTIGISEAHCRLSAMSVSRGVIATITHCIRARIRRTDEERARGRDDVENGNTIRKNEMINVTHYGSVNTSIQDVTRRRRRSHSPAQSDGPPVVDKMRRRLQFYFMNPLEKWHVKRQFPYKLAIQLIKIFFVTFQLCLFATYRYANVNYTWDNKITFSHLFLKDWDSSREITSYPPTTGPLAVYRKDDFYKYVNFAVNAYANIGELAIGPYFYENTDGSVAPMHFCQQKYVNGVIFGFNESYVFDSETETKCIDITAASLSPPANFSSKQYFQDQNFTISFDNLLEAHLRFTLKTVRFRDLGPLKSPDCFRFDLDILFNNRDHDGQTLVTLEAQPARLLCKGDMEYIADNRLERIGRSGVNYIVIGMCTLSLVLCCRAIYRAQLLKREAISFFKKYYQREMTVSERLDFLNFWYLLIILNDILIIVGSALKEQIENKELTGEAWNVCSLLLGVGNLLVWFGVLRYLGFFRTYNVLILTLKRATPQVLRFLICAILIYAGFTFCGWLILGPYHIKFSTLSTTSECLFALINGDDMFATFASMSSKSSLLWWFCRFYLYTFISLFIYVVLSLFIALIMDAYETIKLYYTDGFPRSMLEEFVVGADLINQQSSSPFSTPDSQPHLPNTLSRQQSVTSEMGRRMSVTTAGGLLDTIVETICGCNSSNPDTNQQNESSPHFRSSEDDENQPLLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC75</accession>
    <name>A0A1D2NC75_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC75"/>
    <dbReference type="OMA" id="DLCHASL"/>
    <dbReference type="OrthoDB" id="8250201at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="32646" checksum="18CBB129236E18E7" modified="2016-11-30" version="1">MSKLDLLDLFQASMKQPLKLLDLSNVKIDSDADFLKYMNKVPEMKLRPDKVLPEDIQIITDFSFASPTKQQQEVSSTTVSSGSKSKKISYEDPLPLCMRTTRLEELWALDIHWKMLTSDRPSSKIEAFFFERIVELGRFALADRKQEQATIKAIMSSVVGTPAVTYLIALGFITTRSKRGAVETKLKVCKNCGLELCTGAFCKVYHYEGYTRMILDDDELENQEKDKDELAFLKQVSGAAAASSGGASGKKAQTSKNLQGKKLKMQIKKTKRKKKKKKKAKENVEAVSAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCM6</accession>
    <name>A0A1D2NCM6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Slit 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000090">
        <property type="protein sequence ID" value="ODN02991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCM6"/>
    <dbReference type="STRING" id="48709.A0A1D2NCM6"/>
    <dbReference type="OMA" id="SPPNCRD"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963">
        <property type="entry name" value="ENDOGLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963:SF38">
        <property type="entry name" value="LP13770P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="118"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="336"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="380"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="542"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="712"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="755"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="495"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="602"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="638"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="847"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="669"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="716"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="877" mass="95861" checksum="E38FFA91EC0F01BE" modified="2016-11-30" version="1">MDSKGSITLRKGYFLNYRTCFLLFFIVLFLNQEAETLRTGSSTKARSKSKDDLRSRSISSSSLFLHPAPKERRLSFLNHQLSLLGGKVGPESRISSKIYSHLGDSTTGTDEISSVDVPPNSDIVVGKEIPKGTRILLECQAEFPVNWIYQGDGAPQMQTNTTIPASKKKAKYSATALIGSDDGVVDSKETGEYICRNTQNPEESIRYYIFVPGKSYFIRRGGIIKLSPNDNSLRIPCSISNPDARVTILKSDKGYLTCVVNDTMNYSKKSGFTLKLVEDDENDVAGLYVCMAGVNDSYQLAEYSVIRSYENSTYEYNWEERSVIYDDEFSSELGRNDDICSPNPCGPNAICEVKKNQRTGDPFTCRCEEGYRGKAPKCRSNSLCAPNPCGPNSVCTEDSERNYPRCTCQETYIGRPPNCRPECNLNIDCHPSLNCVNNTCQNPCLSACSLDAVCTVQNHVARCSCPIGTAGDPSNGGTCHKIRLPSLQFFPFFGLRPRPPNRPRPNRPPVRLQEEPQQIFPGDSLPSTDYSEEYSAGELNTISNSCENWPCGPHSQCTPVGEFAHCKCNAGYVGLPPNCRPESVEKYVVAPTLNVEEDITKQNATAPAASEEIPSQDAPHPQEKHLASLNLKNCWNVGFHRPPTSSPPPSSSGGSNSQQESSSEEHQTTNKNPSQRPGSRPGQRPPPRPSNPQENGRPTGPISDGGNNNGGSGSSCTNFCGKNAVCVQRNSTVTCRCKQGYTGPGSDPYTECTPSRNPCHKCGPNSVCRVMGNGSPVCECQPGKLGSPPNCRDNVCRYNNDCPQEQACFKRTCADPCGRARCGQYATCKAINHFAVCACPNDPDKDPLEEGGCPPPEVSSSGRPKRPGFFPPTRFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCT3</accession>
    <name>A0A1D2NCT3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_03875</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:68748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:68752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCT3"/>
    <dbReference type="STRING" id="48709.A0A1D2NCT3"/>
    <dbReference type="OMA" id="INAMSGV"/>
    <dbReference type="OrthoDB" id="2291at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000002">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000004">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000006">
        <property type="entry name" value="Phosphoglucomutase PgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005737">
        <property type="entry name" value="PRK07564.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF2">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="16"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="114"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN02806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="40941" checksum="A3BAEBBC8B919E5D" modified="2016-11-30" version="1">MVKEIFDFGLLKEFLNNFPVVINAMSGVTGPYVRRIFQEDLCSGNPKSTFLNTEPLPDFGGHHPDPNLTYAADLVKILKENPELYQFGAAYDGDGDRNMLLGAGGFFVTPSDALAVLAANLTTIPYFVKTGVKGLARSMPTSGAVDRVGKKLGLNVYEVPTGWKYFGNLMDAGKLSLCGEESFGTGSDHIREKDGVWASLAFLSVLANKKIGVKELLENHWKEFGRNYFLRLDYENVDGEKANKMIADLENKLKSTNPETLTQEIVNAAKESGAAAAPEKYKIAFTDNFEYTDPVDASVAKGQGLRLVFENGFGRLVWRLSGTGSSGATVRVYLEKCDDVSVLGVTLDSLKDLVEISLKLTSLHEVLGVTGPTVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND88</accession>
    <name>A0A1D2ND88_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND88"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905399" evidence="2">
        <location>
            <begin position="26"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="106" mass="11774" checksum="54F56D56E1388D9E" modified="2016-11-30" version="1" fragment="single">MGRYFPASGRSCLLAVLLLAAYAHAEPLRTARIPILPEESPEIQREIVKRNDQPGQQQQGPPQQQQPQPQQQPPQLPSHNLLQKRHSSAVLLRTIMEGVEVATVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDC7</accession>
    <name>A0A1D2NDC7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000081">
        <property type="protein sequence ID" value="ODN03241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDC7"/>
    <dbReference type="OrthoDB" id="5917255at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="204" mass="22625" checksum="AA909D1DD0AB319A" modified="2016-11-30" version="1">MDLVCVQGFTSQNSKMDFHLLGALILTRDAGKCAEEQSFVPSATQKNKAVAESETGKQDFAENEWGFDTKKAGNKTEEELPQILSKNHVIRNTTSFENPKGMGKVTRIFYAILIAYLVPVDTFQSVFSSPTPTFPFWSTDSTTTSQQDGNVNVSSSPFGTDLGDDVLCHPSCECLDTFFDCRKRGPKRGLTEFPDNFPNWVVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDG7</accession>
    <name>A0A1D2NDG7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDG7"/>
    <dbReference type="OMA" id="MICELGA"/>
    <dbReference type="OrthoDB" id="6359133at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="28917" checksum="2CC0BFBBDC76E4FF" modified="2016-11-30" version="1">MAYNLPPPPLDGGGPDFGGGIPFGFPGFGKSFNLDVGAGFGGPGAGFFGGGFPGWGGPYVPVTPLGGLWGFKGDLIVPIVAIGVAIFILILIVLAVKYALAWKLEVLDDLAGNKKWKREAGDAPAVQLQDSNLNKLADIVAAAVYSEGCSRRILCEIGTYARDGKQYPSLLRLMELVVPEEYQGSFTVVRQSAEGQFDCSEHYPCGDKSKNPPNPADNEVDTSPNNQSKPVPEDSQSSASGNATTPASSSPTFGTTPAPSGPQAVFGKFKRAMMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NED7</accession>
    <name>A0A1D2NED7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridoxine 4-oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03064</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NED7"/>
    <dbReference type="STRING" id="48709.A0A1D2NED7"/>
    <dbReference type="OMA" id="HWYGNIN"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="35"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN03621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="133" mass="15582" checksum="446C068E44988572" modified="2016-11-30" version="1">MERTVPQKYASLNSISQVITRRGLLSYHYHWYGNINLMIHLRGHKHDFDNWANLTGDPEWSWEGVLPYFKSYEDYQDLGDEVNHGYKGELRIERPDYIGLAPEFVRGAEELGYPNVDLNAPYSKVFNQFPLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG51</accession>
    <name>A0A1D2NG51_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000050">
        <property type="protein sequence ID" value="ODN04224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG51"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="247" mass="27718" checksum="2208F6D793507210" modified="2016-11-30" version="1">MGSEVSRNTNFSDNRVYATDYPSSFAEKAEMHWKKPSRLELFSEDFYCPLIFEAEAKCNVSFPSPASPLSLMTDSVQEDRHQKSVSQSSQENILNNEVVDENCNIIQNVAIHVQEPEDHNYTSEEQEEIDLKVENAIIASDPDVALELEVKADLAEAWTNTSQPHLQDAASGNSQVLMVESAAGTSQPRMIECGIQTSQDFGLRTLQEDHGQSPKRKLHSTSTATRNVMLPLFCPDCRYKSLDRKCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG68</accession>
    <name>A0A1D2NG68_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Neuron navigator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nav/unc-53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000051">
        <property type="protein sequence ID" value="ODN04222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG68"/>
    <dbReference type="STRING" id="48709.A0A1D2NG68"/>
    <dbReference type="OMA" id="NEMCSKR"/>
    <dbReference type="OrthoDB" id="2161974at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022008">
        <property type="term" value="P:neurogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057568">
        <property type="entry name" value="CortBP2_NAV1-like_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039041">
        <property type="entry name" value="Nav/unc-53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057126">
        <property type="entry name" value="NAV1-like_ubiquitin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12784:SF28">
        <property type="entry name" value="PROTEIN SICKIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12784">
        <property type="entry name" value="STEERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25408">
        <property type="entry name" value="AAA_lid_NAV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23092">
        <property type="entry name" value="Ubiquitin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="546"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="817"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="860"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="825"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="862"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="889" mass="97046" checksum="B5F271CDD0385EFB" modified="2016-11-30" version="1">MEAHVVAAFEQSLSSMTRRLETLTLTAEQKDSELTELKNTIDLLRKQSVEAGLTVPELAGVGTHDESPMARQLSADSVSSINSISSACSGTSHSHTSSPSGQVQMTPSGTPTHSANLITPESPGSKKKHAKGKGWLRSSFTKAFSRSKSKTRNDSSPDHADGMIIDHDGQLRPNNFNGDVNVNGTHHHHRMNNANHLGQTSQHHQSINAQHRNPHLLHHHHQQQQGQNGGLRVVGNSMPTSPLLSPPTGEGRKNNSSCSVSTGSHSPRSNGGGAVSHDGRSRLGSSTGLCEEPPEEPRSVDELKKQLREKEMVLTDIRLEALTSAHQLESLKDTVTKMRNEMLSLKQDNERLQRMVTCKSLTSSQTSLQMGASEGIDRRLSASEVPPPSSSTLEMFLTDSTEKEGKRITVSVYLGVHGCYDRYISPVEGLSAQECIIGTISVSNKTKWDALDSLVKRAFKDYLMRIDPVSSLGLSADSVVSYAVGEVLRSKEGTPPELLPCGYLVGDVTKIRICLRGALHGAVDALAFETLVPKSVLQRYMALLGDNGRIIICGPSGTGKSYLARKLGEFLVARSGKDPCPEAIASFSADHKNSKELRQYLINLVEQCDGSGGIDLPSVIILDNLHQVANLGDVFNGVLSSRQQASPIIVGTMTQSASAPPNVQLHHNFRWVLFGNHMEPVKGLLSRYLQRRLIEVDTQIGTKNLELARVVDWIPKVWHHVNKFLEAHNSADVTIGPRLFLSCPMDVANSQVWFTDLWHYSVVPYLIEAVKEGLQIFGKKAMWEDPSQYLILTYPWPQQLALNTGKSSLQRIRPEDVGYDTKSTGNNAAGHNGNRAGNGDISNDSDPLMNMLMRLQEAANYSGPQSNDSDTTSLDSHVSLDPKDYIATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG99</accession>
    <name>A0A1D2NG99_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">6-phosphogluconolactonase</fullName>
            <shortName evidence="2">6PGL</shortName>
            <ecNumber evidence="2">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG99"/>
    <dbReference type="STRING" id="48709.A0A1D2NG99"/>
    <dbReference type="OMA" id="YQLFEFE"/>
    <dbReference type="OrthoDB" id="432544at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26048" checksum="B799212D0206F1F8" modified="2016-11-30" version="1">MSAEDKFLVTALPSDQFITNLCEKIGDIATEAISSRDVFLLGVSGGSIINFLAEGLPKISTDWSKWKIFLCDERLVPVDDPESTYGCYKQKLLPLLNGFPEENFIQAKLGVSGTESAADYESKLKALWTDDPNSASYGMSDCLLLGVGPDGHTCSLFPGHPVLNVADRWVTNIEDSPKPPPTRITLTYPFINKATNILIAGKGKEKWSILEKVKNGEDFPIGRVENPGGILEWILEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGA9</accession>
    <name>A0A1D2NGA9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein Skeletor, isoforms D/E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000054">
        <property type="protein sequence ID" value="ODN04135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGA9"/>
    <dbReference type="STRING" id="48709.A0A1D2NGA9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="74" mass="8351" checksum="B1DD7F8DA7FDB869" modified="2016-11-30" version="1">MKSAQERCTCAHGVKVYAGVERDSRGRNIPTAVGKLCRWIENGNQQADFFTSYAAYQRSLFLNCDKGHSGMYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHK2</accession>
    <name>A0A1D2NHK2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHK2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113764" evidence="1">
        <location>
            <begin position="16"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="239" mass="26631" checksum="88F93642D39AC75B" modified="2016-11-30" version="1">MLLFLLLLLAQNSHSRVIDCVDDPTSFSKSLWKFNIQRKVASFNGTAVIGVEGTDSKVAKDVYATATFPPGATKNVFLYLEYLNESPRRISIQPSKTSGIDLLPGTLADWTDTVQQVALQSNNEIKLTMLLKTGQSVYFRKMVLYHSRTLMTFHAPTFVSTTTRPARRPGRLVQAPVNQQLAAVQRVTLESNPAQFVQSVLVFAIATATKSADADGRKKEIKNNQFRSQIKIRTFCLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHP4</accession>
    <name>A0A1D2NHP4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Whirlin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHP4"/>
    <dbReference type="OrthoDB" id="10029564at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="174" mass="19576" checksum="5034AE95174BA4D3" modified="2016-11-30" version="1">MQIVASYIGKIPADLNDEDLLKLDDSDEPIPISENDNSNLPQDEQIDGELELDFVRGSNSLLSKRCTTSILQMIEEKARTVLNKSEHSRFTFYRIEYMQGFLPVVAFVRILLELLNTHEKVSRFSPQPILCPLCLHSTQLGFVSFSGTKINNLFSCSLSNSCNVTLATPVRKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI32</accession>
    <name>A0A1D2NI32_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000033">
        <property type="protein sequence ID" value="ODN04923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NI32"/>
    <dbReference type="OMA" id="HCYDLLH"/>
    <dbReference type="OrthoDB" id="2113814at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045334">
        <property type="term" value="C:clathrin-coated endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045807">
        <property type="term" value="P:positive regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000001">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000007">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000095">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.730:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.110:FF:000003">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022365">
        <property type="entry name" value="Clathrin_H-chain_propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13838">
        <property type="entry name" value="Clathrin_H_link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01394">
        <property type="entry name" value="Clathrin_propel"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="506"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="655"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="802"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="948"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1097"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1243"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1392"/>
            <end position="1535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1640" mass="187824" checksum="F4D7DEB26556AB77" modified="2016-11-30" version="1">MTSNIIPIRFQEHLQLTSIGINQANISFNNLTMESDKFICVREKVGDSAQIVIIDMTDPNSPIRRPITADSAIMNPASKVIALKAAKTLQIFNIEMKSKMKSHSLAEEVIFWKWISLNTIGLVTDSAVYHWSMEGDSTPQKMFDRHSSLAGTQIINYRTDPKQNWLLLVAISAQQNRVVGAMQLYSVERKVSQPIEGHAGTFAQIKMEGNPEPSNLLCFAVRNLQGGKLHIVEVGGVPQGNQAFAKKGMDVFFPPEAQTDFPVAMQASNKYDIIYLITKYGYIHLYDLESGQCIYMNRISSDTIFVTAPHETTGGIIGVNRKGQVLSVTIDEETIVSYIVNNLSNQDLALRVAAQAPKGILRTPQTIQRFQQVATQPGQTSPLLQYFGILLDRGQLNKFESLELSRPVLQQGKKQLMEKWLKEDKLECSEELGDLVKQVDPTLALSVYLRANVPNKVIQCFAETGQFNKIVLYAKKVGYTPDYIFLLRQLMRVNPDQGVGFAQMLVQDDEPLADINQIVDVFMEQNMVQQCTAFLLDALKNNRPSEGPLQTRLLEMNLIAAPQVADAILGNQMFTHYDKSHIAQMCEKAGLLQRALEHYTDLYDIKRAVVHTQLLNPEWLVQYFGSLSVEDSVECLKAMLTANIRQNLNICVQIATKYHEQLTAKALIDLFESFKSYEGLFYFLGSIVNFSQDPEVHFKYIQAACKTGQIKEVERICRESNCYNAERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVVGGLLDVDCSEDVIKSLIMVVRGQFSTDELVEEVEKRNRLKLLLPWLESRTHEGVVEPATHNALAKIYIDSNNNPERFLKENQYYDSRVVGKYCEKRDPHLACVAYERGHCDRELIHVCNENSLFKSEARYLVRRRDPELWAEVLNEENPFRRQLIDQVVQTALSETQDPEDISVTVKAFMTADLPNELIELLEKIVLDNSVFSDHRNLQNLLILTAIKADRSRVMEYINRLDNYDAPDIANIAINNQLFEEAFAIFKKFDVNTSAIQVLIENVSNLDRAYEFAERCNEPAVWSQLAKAQLQKGLVKEAIDSYIKADDPSAYVDVVETAHENESWEDLVRYLQMARKKARESFIETELIYAYAKTGRLADLEEFVSGPNHADIQKIGDRCFESGMYEAAKLLYNNISNFARLAITLVHLKEYQGAVDSARKANSTRTWKEVCFACVESGEFRLAQMCGLHIVVHADELEDLINHYQDRGYFEELINLLEAALGLERAHMGMFTELAILYSKFKPEKMKEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVTAMMAHPTEAWRESHFKDIITKVANIELYYKAIQFYLDYKPMLLNDLLLVLAPRMDHTRAVNFFTKVNHLKLVKPYLRAVQSLNNKAINEALNSLLIEEEDYQGLRTSIDAFDNFDNIALAQKLEKHELIEFRRIAAYLYKGNNRWKQSVELCKKDRLYKDAMEYAAESKNPDIAEELLVWFLEKGNHDCFAACLFHCYDLLHPDVILELSWRNGIMDFAMPYMIQVLREYRTKIDRLEELEMQRMEEGPVNDQKSMIMEPQLMLTAGPGMGMPPAYTQAYPNAYGTGVPYQGYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIJ7</accession>
    <name>A0A1D2NIJ7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein uL10m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">39S ribosomal protein L10, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01579</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIJ7"/>
    <dbReference type="STRING" id="48709.A0A1D2NIJ7"/>
    <dbReference type="OMA" id="RENRMIA"/>
    <dbReference type="OrthoDB" id="360689at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="254"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="33087" checksum="9B63E4ABACB791DC" modified="2016-11-30" version="1">MSALLAKSPASKGLCRVWNLMAQQLRFEGNRPNLKNPKPAHWNRARMLAVCQPVYPPGPRNCEKDALLQKKADNVLEVGIFYRYVWTNFVSRLFLGQGKLRTGTSGDQSRELAFLPHNDHSYSKHDLINIRGSLYDMNFDMRIQKEVNRNMARMSLTGTRWAPLIPLFEGKTSLGFCKEDDISRLMKALKKMPQFLLLAVVAHNRILTKNAIEELEKLRNITNVRTQLCSSLALQSVTLSQNLTANVSALSHSLTTYSQPGEDTSSSSSSDSDSDSDSDSSSSSDSDKEDNNKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIQ3</accession>
    <name>A0A1D2NIQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transport and Golgi organization protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIQ3"/>
    <dbReference type="OMA" id="RIFHFEL"/>
    <dbReference type="OrthoDB" id="191601at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="332" mass="37029" checksum="B904E32ADD7859C7" modified="2016-11-30" version="1">MCILFMYVANCAKKPSNSGNNAPPTYKLIIASNRDEKYNRATKAASFWENTDSHILAGQDLQEFGTWLGISKHGKLAVLLNVMGKTTEQPESLPPSNKTSRGSLIIGYLRSPPGLLGSTYCNSLCEDPESLDLRTAFNPFHLITIDIHGRNGNCERPETDTSTVRMTYLTNKRNSSIPTPQPECMTPQINTCEYYAIGNSMMDRPFQKVLTGRTDFKNVVEKYSGAEASETSNESLTNEILEFLRSTKKCFPDESLTEHAKGTIVPPQMLPGLSSRFISIPQVQYGTRTNTIIIVDTANNVTYHEWTMKEPIDGANPTWLHSKFQFSLSPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMZ6</accession>
    <name>A0A1D2NMZ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMZ6"/>
    <dbReference type="OMA" id="ATHETVF"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905786" evidence="2">
        <location>
            <begin position="23"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="471" mass="54323" checksum="58B3B3B02ECAC55B" modified="2016-11-30" version="1">MEIYSLLLLTAGLLTIIEMAAPGGKDSHTSILKIALIVLNEKNEHGEFILGCPLSMEDLDNLQSEMMLRIVVRLMRDFIVNLPLSRKIPLSDFNQFKTGEVTYDSGIDRIYHAAAKIFPEENPLHFSTLLLPSRDPKRTKAVIAYIMSFYWMCDDLYARFETSFEDVIEENKEKVKIYNDIEDLKLEISNKIQEKETERDRIPSVQKEIQCIEEKIRKEQIVLTKLNEEVEKHMNIFKGKEGYLKVLKQQLEQLELDRLRLEGQIVANPDEILGENTTIRKQVGSEIAQRDAFGSEINKLTKKCDGYENLINSANNALHDFENVTAMMQDAKSRLVEYMKLGKEVSSESKKLNAELDHLAQQYSVKADELRHKKELCSGRIQKVVNEVKILQTQILQIRGKIKDERSAKQTYSLKLMEVCRAIDELKASISQHIRTRKVDLPKQRFLLEMKTKQELENSLKQLASFSSLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Q1</accession>
    <name>A0A1D2M1Q1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006840">
        <property type="protein sequence ID" value="ODM86896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Q1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903375" evidence="1">
        <location>
            <begin position="28"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="82" mass="9166" checksum="5BA7C353CA57B520" modified="2016-11-30" version="1">MRCSHLVMLIVVLPVLLSSLEIQLAQGIKCYSCGPCPGKGEERKWSGSMTPVRNYKDEGFQIPSAFPDLLIQSDRRPCQGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M243</accession>
    <name>A0A1D2M243_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dynamin-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19643</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006339">
        <property type="protein sequence ID" value="ODM87039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M243"/>
    <dbReference type="STRING" id="48709.A0A1D2M243"/>
    <dbReference type="OMA" id="ISHEEWA"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="4">
        <location>
            <begin position="32"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="40355" checksum="F8AC43866330FC2B" modified="2016-11-30" version="1" fragment="single">MEGVERIDGLIPIFNTIHDILERTKVGPGSVEIPLPQIVVIGSQSSGKSSVLENLVGQPFLPRGSGIVTRCPIVLRMILTPGNDTWCEFFHKPNEKFDDFRKVEQEIISRTDEIAGTDFGITSESIKITIYSPTVLNLTVVDLPGLVKIPVGQQPDDIEEQVKNLILGYISADDAVILAHKNCQDGGPNQERTIVVLTKLDLTDDYSKMTDVLNGKLGYVGVINRSQDDLKGDKPIEEVLKHEKAFLAEKFSSISAKHGISCLAKKLNRILLQRILACCSGLSLNIRNLSTASESELRELGVDEEMTEEEKKKELFKIVDEFAKEYKAQIDGMSRSEVQSMNLTCGARIDIIINNNLPNELDCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3B0</accession>
    <name>A0A1D2M3B0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the calycin superfamily. Triabin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005358">
        <property type="protein sequence ID" value="ODM87424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3B0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030682">
        <property type="term" value="P:symbiont-mediated perturbation of host defenses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005657">
        <property type="entry name" value="Triabi/Procalin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03973">
        <property type="entry name" value="Triabin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903425" evidence="5">
        <location>
            <begin position="29"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="22568" checksum="1BFC64932E4DE7F6" modified="2016-11-30" version="1">MESISKSAILSVVVVVFVANLSCIKSECEPPKKIVEFQWHPKEAKEGGYFTPLAMQNDTNIVKEMLQGSSLNPDQDLKKICIRVRYSEEGKEASVVGYHNMTSQFKCSPTGNGKEWSFDCQHQSGKEDFSHKMYVTLTDNKTFAFVIRCWKNGLRGWTVFSTRKELHEDSHFHILEHAKSQGFETAYALPLSYKSCNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3P5</accession>
    <name>A0A1D2M3P5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alkyl transferase</fullName>
            <ecNumber evidence="4">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19118</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate</text>
            <dbReference type="Rhea" id="RHEA:53008"/>
            <dbReference type="Rhea" id="RHEA-COMP:19494"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:136960"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.87"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01005053">
        <property type="protein sequence ID" value="ODM87564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3P5"/>
    <dbReference type="STRING" id="48709.A0A1D2M3P5"/>
    <dbReference type="OMA" id="KIEVNCL"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="30573" checksum="018D5F01A3CDD65B" modified="2016-11-30" version="1">MDGNRRYAREQNLQTIEGHRKGKSKVEKIVDWGTLCGVKEITLYAFSIKNFKRTAKEVNQLMKLFRSHINDILGNDEEMVHGRARYQIIGDWSLFPNDLKPIIAKLMAETRNNRKITVNFAFVYTGRNEITSGVKHLLNGVANKALKLSDVNENLLDKSLQLYSMSPVDLLIRTGECRLSDFLSWGSSDHAVICFRDEYWPSFSYWGLLASIFYYQANKFRVPQHSKNDDNIGQQSGEFLQMLKEKLWKNVENHDERQGNFGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3X6</accession>
    <name>A0A1D2M3X6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004931">
        <property type="protein sequence ID" value="ODM87632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3X6"/>
    <dbReference type="STRING" id="48709.A0A1D2M3X6"/>
    <dbReference type="OMA" id="TELPRWK"/>
    <dbReference type="OrthoDB" id="10053513at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33053">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33053:SF24">
        <property type="entry name" value="TRANSPOSASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="40597" checksum="80B8922F19CCD669" modified="2016-11-30" version="1">MSQKRKVIVGRRRIQQIAAREVALAFSKSTENKLYANQTSTDSEHTDNESDIKPFNLLESLKEWALTHGINHSQFSSLLKLLRRHDCHQTFPADSRSVIKAHDKVVEKCVEPGKYVHFHLYKFVESYISRLPEVKQLALQINIDGLPLFKSSAVHVWPILGYVVGVSCEPFVIGLYCGSKKPGSVNKYLEQFVQEFISLKEKLLLRNIDLQLHSFICDAPAKAFIKGIKGHTGYFGCDKCEVEGEYINNRVVYLKNNARERDDISFRTRRDDEHHLQTTVLEEISTLDMIKCFPADYMHLICLGVVRKLLTVWIKGKPSSHKLSGKKISELSDVLISYAPHIVSEFQRKPRWSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3Z2</accession>
    <name>A0A1D2M3Z2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004861">
        <property type="protein sequence ID" value="ODM87679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3Z2"/>
    <dbReference type="OMA" id="KCNANAT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="221" mass="25065" checksum="1F29CEDA1CEB015F" modified="2016-11-30" version="1">MSWVGHDTKQFSVVKVSDLVDGNLRTNPSKAVGSITMCQWGRNKEFKAKVLKIAPKKVPKRNRKPKLPSAATRTLDSVLATFDESMEYEDPAQNEVLSGSNQIRKERIDVVIPETESDVHENCMNDEIEQAHVNVVTGDIAESETVDYKAKYKQLKIKYKDLKTRYRALKNETGSETMVEIYPSSGVLMKKGDLDAIKLLSNQMNVLARKICFVLFLLRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M422</accession>
    <name>A0A1D2M422_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004798">
        <property type="protein sequence ID" value="ODM87720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M422"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12985" checksum="F23905BC7E10D883" modified="2016-11-30" version="1">MTNNREDIFMELRRNQPYRLQTAIVAGVSNSHKEQINDQDDRDPSSPRKQYRRPCTKQNMRLQQMQERVCFKQQNMKGRKNCTVPTRIERDDITMRMSSSNLNCSQNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4S5</accession>
    <name>A0A1D2M4S5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Long-chain fatty acid transport protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18708</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004306">
        <property type="protein sequence ID" value="ODM87976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4S5"/>
    <dbReference type="STRING" id="48709.A0A1D2M4S5"/>
    <dbReference type="OMA" id="DERGCCI"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="209" mass="24034" checksum="90CC410FD18DDCAC" modified="2016-11-30" version="1">MTTNFWKDVHKYKVTVCMYVGELCRFLHNQPVNSELEVGHSLRAFFGGGGLRPEFGQLFRKDLSQSRRKIGACGYIPIWLQPSHPIQLIKIDQITGEIVRDEKTGFAIRCEDGEPGELIGKIIDSVPMSRFDGYTDKEATEKRIARNVFKQGDKYFRTGDCLCRDKYGYYYFQDRIGDTFRWKAENVATTMVEAVISKDLGMRDNTVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5F9</accession>
    <name>A0A1D2M5F9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4806 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004043">
        <property type="protein sequence ID" value="ODM88141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5F9"/>
    <dbReference type="OrthoDB" id="8887905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28581" checksum="1286FE89908E7E4E" modified="2016-11-30" version="1">MTATHTSPSVGLGSSGPNNEQNADSTVVDLLKKLVLDSGDGWRKLETCVEHRVQASGQSCVDSCLIPHPFSTVADFQAFDTVLDDDKKEVLKCELLRCGGDTTVEFIGRVMKKLMTNEVGLKYSLWGFRNNINFSKTAAWEVVKDSALSFKRINSTEKAIEKSVSEWFRHSGDRIKQQNTNLIKPSGSTSTTNSTNFRPFLTNSSKCIEKLIVTAYKMDIVRHRNDIGMFTRLGQQHVQWMSNGLSIRASTGPKNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6P1</accession>
    <name>A0A1D2M6P1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trypsin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18091</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003404">
        <property type="protein sequence ID" value="ODM88591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6P1"/>
    <dbReference type="STRING" id="48709.A0A1D2M6P1"/>
    <dbReference type="OMA" id="KIRWELS"/>
    <dbReference type="OrthoDB" id="5565075at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="38"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="30349" checksum="1D76F134A3120B26" modified="2016-11-30" version="1">MRLEFVVLMLALGFFGNIGGYDSVRLRQKIRWELSPKLHGGPVGAIALIQILWEDPVTPTTGHWKNRRRNKCRLSETPYQLRLIIRKPGSVTNCGAVLVAAFNIQFALTAAHCVNGATASPSKMEVIAGLHNLKRNTGSEQTKNPIWVVKHSRYTSGNSANDIAILFFATRFNPTSAVRPIALPRHEYPQPGQVKISGWGSTSIGRPNSQSIYPDILQVLTISTFRQCGMPAGQRRTSCGIDSNGRMYVAGLSSYHLGGCGGGRFPMFYTRVSAYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M754</accession>
    <name>A0A1D2M754_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coiled-coil domain-containing protein 81</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17887</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003175">
        <property type="protein sequence ID" value="ODM88796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M754"/>
    <dbReference type="STRING" id="48709.A0A1D2M754"/>
    <dbReference type="OrthoDB" id="125906at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026295">
        <property type="entry name" value="CCD81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040673">
        <property type="entry name" value="CCDC81_HU_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028034">
        <property type="entry name" value="HU-CCDC81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14362">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14362:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14908">
        <property type="entry name" value="HU-CCDC81_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18289">
        <property type="entry name" value="HU-CCDC81_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCDC81 HU" evidence="2">
        <location>
            <begin position="241"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="CCDC81 HU" evidence="3">
        <location>
            <begin position="325"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM88796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="699" mass="79110" checksum="C0788B8603D0918B" modified="2016-11-30" version="1">MASEHTVELSTAGSLALGIPSSSDTKYKGAATTSDKKHIAFSSNSQEAVPILQLKKPAKRRVKLADDEDGSDEDEELDINSMKSHQKIDKAKINRRKTPFPDMRFRSLDDDDDDDGEIIGPEDENYEGVDGLNYGYEDESEEDEETDGSYLTANEASVKKDGPPHPHKVLLHRGSSAAINVADGLVHDEHLHGLEGAPPTPPRLSLENINELLGMDEMLDDDQRSFVEAVKQHAHTLLERECTVREVILVWENCSKYIILKMLEGFAVKVPGLGTFTLSILPNDLAADKMVLRKHRKFPVFKICQHLKDMYDLEEENALYQCNAPVVALNLSVIASDTKLPRGIVDGIITEVLQSFARGIITNKTLEFPFPYIGKLYILQRRVSMAFYQQFCEGLSFDFDAMPSTLQYVLPGNMSPLMYHRPQPEFQSVFHYRDLRLVEEKIAAKPRPYAKGNFIRDSSESPCNFLQKLHSHSNLLFHCSCCKNEKSEEGDPPCEYSQDYERINKSCCTQHGKFSFQQPDGSSFSPQPLYKTLKTGNPILDRLTDDKCLLQQALGCWLKRDYVHTLGTENVGKHFDRDYFHHQRHHRTTRHRSIERRSGADHGDDDDLDNDKRRSSAAESATHEGSPAPSETSLTSFEFLANNEILGEYGGYHEYEHNQDGMYNHLESEEEELEFQKVESIEGELPTPSGDGQMEEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M841</accession>
    <name>A0A1D2M841_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Malectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_17527</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002857">
        <property type="protein sequence ID" value="ODM89153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M841"/>
    <dbReference type="STRING" id="48709.A0A1D2M841"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021720">
        <property type="entry name" value="Malectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039155">
        <property type="entry name" value="MLEC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13460:SF0">
        <property type="entry name" value="MALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11721">
        <property type="entry name" value="Malectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903606" evidence="10">
        <location>
            <begin position="21"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="Malectin" evidence="11">
        <location>
            <begin position="112"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Malectin" evidence="11">
        <location>
            <begin position="421"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM89153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="674" mass="78545" checksum="3330EC53BEA14090" modified="2016-11-30" version="1">MNSYLITVFLFLGSLNPSLSLPEHNHDHDTSDPEILTWDEHSGHYPSDNSSHHRSKRQNRKECWRWCERINDCRYDGCYYDMKTLHCYQSQWHAQYYPVIYSGTAYSPQRMAICVNFGGYSHQAANGYYFHQEPTWLGGFSYSVNNWITNMHDSGDHNVFRSARLDWKILYKILFQYDGHYFLRMMFAEIKPIHFRYQIIKFNYVWIIKNAFDVASYVGGRFKALECYFYPVISNNRRHISIAGQGGWLGPFTAVEVFNIKPFGLAIANGLCLTHFHTCTRWCNNKDACNRHWECWYDDVIRHCVPRSHHEITCRNKGTDRQQCEAAGCNYCCAKLHCQASWDSMAHCNDGCLNHCKEQKKCIMDPEECVYNPETQQCTDKPYDKEKCPTYELLKDSLYTETHLNNCGMDKIRSCVRVPYGINLGGQAYTDDGGAPYIADFYPIYSDPYISDIDKCLPEVEGATFHNRYVFHTFRRLWRKHCFALPIPEDGDYTLQVKFFEFGFLFNRSAGRVFDMLLNDIPVKENINVAKSGSGLRHRYEIVQDFEVRENVRQVLANGLSDKIKATRIHLRFVKKNPGDFDWPQVSAIQVFRTRKCTNELNREQCFLAGCFHDPVKKTCEKKKEIICNPLEGKYCDPFLLVLGRQIELPPTTTMRPAAFGCFVTIYTALSRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8A0</accession>
    <name>A0A1D2M8A0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002813">
        <property type="protein sequence ID" value="ODM89200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8A0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013198595" evidence="1">
        <location>
            <begin position="16"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15495" checksum="C50F2136E8D41206" modified="2016-11-30" version="1">MKVFASICLLPTSLCHSGALVNHFREVEKERENQTGPISGVSGCNLLVITFASGSDVGDSTGFVLEYSVLTSSSLSPLSQDYIVNSGVAGIIRHPSSGSRYENYELDTFVILPSLGSNTNVIYFRDTLEANYCYDSLSVYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8C1</accession>
    <name>A0A1D2M8C1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002790">
        <property type="protein sequence ID" value="ODM89228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8C1"/>
    <dbReference type="STRING" id="48709.A0A1D2M8C1"/>
    <dbReference type="OMA" id="IHEVECE"/>
    <dbReference type="OrthoDB" id="8191949at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004211">
        <property type="entry name" value="Endonuclease_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31511">
        <property type="entry name" value="PROTEIN CBG23764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31511:SF12">
        <property type="entry name" value="RHO TERMINATION FACTOR N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02945">
        <property type="entry name" value="Endonuclease_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1087" mass="127576" checksum="F1A3B7707B87BA9A" modified="2016-11-30" version="1">MRCPVLECCHEGTREVIVLHMRVQHPQVGGAAASTLHILPFVEIRAFRGYLRTYRHRTASGETIMTPGDYLASVHQPVLNIIAVNTTGNRSIKVQISLVCQFYRGDEGTPNEERCVHFLNSDTHVVYNVDEFETFLGSVLSEIIRIVNIFQEHGSGWRVKKFLGSDIRVAKYNPLRGRCLIQIPDHIKRKRVIVNVRNLDNQCFKWAFLSIMHYKDVTSKNRFRVSNYKKFERKYNFLGIKFPITMRGITKFEEQNNQKLFAVNIFEEIDETTTIKRMSPHAHNPEFKCVDLLLIHDDDVGLSHYVGIVDIGKYFGRRNYHKQKFCYNCQRFYGTKTFQTHTKDCSQFKTQKVKMPPLVIKNGVIGKPILKFKNQHKDIPHEYIMYLDLESLMNTNIDAPNTNNTTKLAQHIPSGFQLFLIGRTEKIVDYKLYRGNDCIKVLFQTIEEFVHRVKEVQHDLTPMKRLTHEQLIHYHKTNICWVCENDIPKFKKVKEHDHKTGEYRGPACYSCNSRYTIKRSKIPIFTHNFKNYDVHLIIEGFEFYNGSIKVIPSNAEKYVSIICDKFVFLDSMMFLSASLESLVSRLKESVDFNVGFKLMIQYFGSEKAMDLCRKGVYFYDYVTCFETFNETIFPTKQQFFNKLSDANISDEDYEYACYIYKKYCKNLGEYHDLYLITDTLLLACVMESFRDKAISFYDLDPAQYFTLSSYTWDAALKFTGVKLELITDPEIYQFFELGMRGGISMISTRFASANNRFLKSYNKELESSFIIPWDCNNLYGFALQQMMPVSDFKWKKRSFLRKITNEDILKWDDEGVKGYVLMVDVSYPEELHVRDSEYPLAPESTNVPYESLSVYQKSLLETLDIQYFEKTKKLVPHLGCRKRYVVHYRNLKYYIKKGLVVTKIHKILEFTQMQWLKPYIDFNTFQRQIAADQFSKDLFKFLINACFGKSCENVRKHREIEICNNSDQPIYTGFSTLDLSKLVMYEFHMDVVKKRYGERAKLLQTDTDSLSYHITTKNLYKDMKRMQTHFDFSDYPRNHNLHSDMNKKIMGKFKDESNGKAISEYVGLAPKLYSFKGDTIWKKAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8R2</accession>
    <name>A0A1D2M8R2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NFX1-type zinc finger-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002688">
        <property type="protein sequence ID" value="ODM89376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8R2"/>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="411" mass="45431" checksum="385F780C3F333582" modified="2016-11-30" version="1">MSTIQYFKDLHSTGVFGGMLVARYLVFMSAIKLFLGQRLAKSTFLITPMFSGAGMTKATTACAVLPTNILLVIWIIIDMTDQVAFVTTGQDTRSYPHNWPCSSESSRCVERVRMWPQGFSVFSTGTSHFKAHVLVTRQVFLVLQLTRQPLCHDDRALVSQWIHKTRSLQLVSTRESFQNSVWHGGADLPTFARHGAPLDMFFLTPFDYKGIRSGPSVAGQRTAVAHSRISSQLSPQPPNFKGAKEFTFTCVDNFQGEENDIILLSLHVARATKKIKSDLWDRQPDLCRSFPSKHGMYIVGNLDSLMRASPTWKQIGAKLEAGGCGLNCELILECAPLSFALPRKDHSNTLVIKGVRKHVQRSTSVLPNVAGLPSMPNACFENVPLWTRAGGSVFCGSADLQCSVIDEEAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9G4</accession>
    <name>A0A1D2M9G4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamate dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002525">
        <property type="protein sequence ID" value="ODM89579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9G4"/>
    <dbReference type="STRING" id="48709.A0A1D2M9G4"/>
    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF13">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="2">
        <location>
            <begin position="41"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="273" mass="30086" checksum="F789DF8A2F6B5F19" modified="2016-11-30" version="1" fragment="single">SSWLISWNSKGKTSLVTRDLSANPLGPFTQQRPLSPAAAASIPHPEIQEWTAASTTLQGIDLLACSTRYKTSAWTRLSRDFPAAASQYQRHWPCMFRTLPTSLHSRREQRRLNAHSANARLKFSAQASIHLDGGECRLTPAAHNILPGEEGPVLPDLYLNAGGVTVSYFEWLKNLNHDSNLHLLQCAGEPGERSLDGERTHPVEPSASFLKRMGGASEKDIVHSGLDYTMGRSAKNIAIVAKRYNLGLDLRLAAYIHSIEKIFQTCADQGLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAH4</accession>
    <name>A0A1D2MAH4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002253">
        <property type="protein sequence ID" value="ODM89987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAH4"/>
    <dbReference type="STRING" id="48709.A0A1D2MAH4"/>
    <dbReference type="OMA" id="STNCYLA"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF22">
        <property type="entry name" value="PROCTOLIN RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="59"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="43239" checksum="1943791F83C25013" modified="2016-11-30" version="1" fragment="single">MYADNLLNEYLNVSSMDANLENIATEQKYPAGDVLFRDLSRFWVQFILVPIVVVVGVLGNIIVIHILTRKSMHSSTNVYLTALAISDLFYLLFTASMSWRHYPSVNRLWLYWSYTPVGLWITDAFSSSSVWLTVSFTVERYIAVCHPISGTNFRGEKRAGSIASAMYILCFAFTAPTAFEWELVAAGNQTSLNTEQSRYSVERTAFGKNETFRFLYHWFTTIIFVLLPLIILTILNSFLVREVRKSRIARNPPIDDFREDSISARHIQRQREENRVTVILIAVVILFIFCQLPTAAVLIYSSFISLPASGSAEENILLGVGNIFNLLVAINAASNWILYTALSGKYRRQFCYCFMSNQQTNRTVPARVNNAFDLRQFPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAV5</accession>
    <name>A0A1D2MAV5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01002152">
        <property type="protein sequence ID" value="ODM90125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAV5"/>
    <dbReference type="STRING" id="48709.A0A1D2MAV5"/>
    <dbReference type="OMA" id="PMKHRER"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032787">
        <property type="term" value="P:monocarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009093">
        <property type="entry name" value="PRK12429.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="271" mass="29299" checksum="0A9B11A4C56B90B4" modified="2016-11-30" version="1" fragment="single">LLANYAALLHSGKIDEKPDQIGICEISLLFKMSGSESLRGKCVVVTGSTSGIGLGIATEFAKAGCRILLHGLESESQVSNLIKEIASISNEMVAYSNANIADQEQCKALIEFATKELGKVDILVNNAGVQFTSPVQDFPAEKWKWLMDVNLNAPFLLTQAVIPQMYERKWGRLIHIASTHGKVASKNKTAYCAAKHGLLGFSKAVALEAAGTGVTSNCICPGWVLTPLVQQQVEKISKDKGISFEAAKMELLLEKQPSGEFCFSAQLLRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAV7</accession>
    <name>A0A1D2MAV7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA repair and recombination protein RadA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002152">
        <property type="protein sequence ID" value="ODM90128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAV7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="13311" checksum="8EFEF69D15B589B8" modified="2016-11-30" version="1">MNRATFFQSAEVRQFYRSKFGKLHCSPPLPKSNFTLVSEEFVISKPVHDMSFFWCKYWGQLVVMLNQIAHRNKTIFFPRRLNLGAQVVGHAASSKCFCYSEAKPEAEGDQARLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAX8</accession>
    <name>A0A1D2MAX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS-type transporter SLC18B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002141">
        <property type="protein sequence ID" value="ODM90155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAX8"/>
    <dbReference type="STRING" id="48709.A0A1D2MAX8"/>
    <dbReference type="OMA" id="IFICAIM"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF26">
        <property type="entry name" value="MFS-TYPE TRANSPORTER SLC18B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="153"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="413" mass="44144" checksum="B15ED9EBC078F06E" modified="2016-11-30" version="1">MLAESKGVRPSQYGFVLGIFELTRVFASPLYGTFMNQLGAKRIYILSIYIVGISSVLFGLLDKISDPSAFLVGSLLLRAVLEASFGIGTIVAPPIGGLLFQLAGFPLPFISVGLLILAAVIFICAIMPVATKSTDGQLPSKGFGIFTVLRVKGMLFSVTGVFVAAYSTGFLSASIEPHVRQFDLTPVETGLVFVINWGVYAVSAPGWGRICDKTSEPKYVALIGAVLLTVGFMLIGPIPFLPIKTNLWLTCLGAVIQGLGMGAGFVSSFILALRNAFGAGFPDDVATYSVISGMWTSFMAMGLFIGPIVAGYLVEIMGFQWGSVFVCGATFTLIIATASSIMFNGSSTNQSETDPLIGEIIVRKFSDNNNRQNLIPPLLDKSKNTINAKKERFSSVIPVFIGNVHLSVNYSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB18</accession>
    <name>A0A1D2MB18_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002124">
        <property type="protein sequence ID" value="ODM90187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB18"/>
    <dbReference type="STRING" id="48709.A0A1D2MB18"/>
    <dbReference type="OMA" id="QLWVIAK"/>
    <dbReference type="OrthoDB" id="28186at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015643">
        <property type="term" value="F:toxic substance binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040416">
        <property type="entry name" value="TMEM181"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054077">
        <property type="entry name" value="TMEM181_GOLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047843">
        <property type="entry name" value="WLS-like_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31918">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31918:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21885">
        <property type="entry name" value="TMEM181_GOLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06664">
        <property type="entry name" value="WLS-like_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM181 GOLD" evidence="8">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM181 GOLD" evidence="8">
        <location>
            <begin position="166"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Wntless-like transmembrane" evidence="7">
        <location>
            <begin position="284"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="508"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM90187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="539" mass="62508" checksum="CB5FC543918785F7" modified="2016-11-30" version="1">MESGNTLGYSYYMPKGGLTRLKSIIPLKCCDLFGVFDRYLAPAYHHDRCERSVQMKLYSMHKREFVIIFLGFFVALGLAVFIGLVGPPITWSTEIHASYLDNVTDMSTGPFVLKSPQLTTYNQQLWLISKLEIESRDDECHFICRLNLSKIVSCSIFLTLFLMRRRLFEKTFGISLDLYGISTGTVVKILNTSNKRSRHLKCKGECEPFTVLHLGFIDFAKYFIVVRFSDLKGVHERYHIKDVDFYFKTYNPNFTQMEMSFRFIYSTACFGITKIDWSIEQNGYPLFPLMFLVNSTLLGMMDAIFQVSFMSTLLIFWLSIYHGLRQVERRFLTFYLPKFVLVGSLWVSAMILATWQKLNTTKDPTYSYEVETEKFEKLKNFFSVCGICYLVYLTYLILKAYSELRSMPYFDLRLKFLTGLMLIVIKLTIAITYMRFGMDILEDHFVADLSTKYSSSAEFMCFYGLLNFYVFTMVFVYSPASSTVLNNSSQITKDNPQFSMIDDSDDEVIYGSDEDEDTKTPLNSNAHSHSTNNHHDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB90</accession>
    <name>A0A1D2MB90_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein Star</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002092">
        <property type="protein sequence ID" value="ODM90240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB90"/>
    <dbReference type="OrthoDB" id="6357215at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="74"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="533" mass="60100" checksum="B25639E1BF59C580" modified="2016-11-30" version="1">MGDYRHYIMGPGAHQDDPCLLEVVKEQYLIPPSTLPYNLQKADVNQDIPSNLEKFKILEDHIIDNEKGPGFFIECGANDGEFISPTLRLEKNYNWSGLLIEGNPGPFSTLAKKNRKAWIVNAAACITPNANKITFFTNPNTTGLAGLNSRKEHGVSVELSVQCIPLYTLLKALNVMEVDFFSLDVEGSELAILRTIPFDKIKFKFLSVEHGLIPGGRPALQTFLESKGYFFLKEIHDHLTGDSAFITFIFNCGLRLYVPLAFKDNNTDILPTNPEVSSCCLLHLIASSKFKPPTLLKRNLLIIASAFQATVAVQLDEIAELCPGNFITQDYNSTWESDPDNDLQYWIPLASKSFVFHMMQNFYKAQDFNYLSETHLENACLSITKPNKFGWDISEVKGYADKSFQLQIVRTQFPKLYRFQFPYPNEGLSGYASVALSDSKSYNVFDFCLDNGLRSFAVFSKVRYMPPTDISVIKAHMKSLGFKEKQFVTVEVDPCPDISIEDPPVAAPLSAIRIPKYFVSPGWALPSYFWKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC38</accession>
    <name>A0A1D2MC38_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001932">
        <property type="protein sequence ID" value="ODM90499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC38"/>
    <dbReference type="STRING" id="48709.A0A1D2MC38"/>
    <dbReference type="OMA" id="CIAVEEM"/>
    <dbReference type="OrthoDB" id="7633492at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000159">
        <property type="entry name" value="Speckle-type POZ protein B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="37"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="217"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="378" mass="42687" checksum="A8DBF793FE39BC2C" modified="2016-11-30" version="1">MNGAGVNSSENSAKRLCLGSAAGSAHYLSTTNIEKEAFSFLWKLNDYSTSSNFKKITSPIFHGGPKSNHSWQLLLYPKTNLEGVNYLGMYLHLVEFGDTWFRSFGTRKISVRFKFSVLDENGCASRPWNVPLVEFSKSSTTWGQYKYIRCSDLLSPTQPLVVDNCLKLLCEVWILDMKHSVQKCNPPTFPTEEERDKARKLKLASNGRKMFKDSILTDIVITVGETTFKAHKAILSANSPVFAAMFTADMIEKEQNSVVITDFEEDVVKSMLQYVYSGEIGEPNEQTPRLLEIAEKYNLDELKQDAEYAIAQTLNVFNAVEILMLAHTQNASFLKSCTMNFINCNKDEVMKTKIFQEAANDPATKDLFVELYHSKNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCB9</accession>
    <name>A0A1D2MCB9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001915">
        <property type="protein sequence ID" value="ODM90534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCB9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903794" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="55" mass="5684" checksum="6AE2AF308B016755" modified="2016-11-30" version="1">MSKLFAVLLLVAMVFAIATANPAPVPVPQYLTGYGVGLGSYSYNYPTVGGGLIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEL5</accession>
    <name>A0A1D2MEL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter G family member 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001594">
        <property type="protein sequence ID" value="ODM91322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEL5"/>
    <dbReference type="STRING" id="48709.A0A1D2MEL5"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051449">
        <property type="entry name" value="ABC-2_transporter_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30294">
        <property type="entry name" value="MEMBRANE COMPONENT OF ABC TRANSPORTER YHHJ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30294:SF38">
        <property type="entry name" value="TRANSPORT PERMEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="7">
        <location>
            <begin position="39"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="267" mass="30123" checksum="17F6ACB04AA3E3CE" modified="2016-11-30" version="1" fragment="single">MAEIMNNEPPQSSFLGGSVARIKALAKKNSVTLLRNPILLFFIVWIPAIEMIFVGIAFGSDPKYLKIGVVNHETNNTICSKYNPKRGECAWRNLSCVYLNHVPEDTVELIPFGSEYDAESAVVLGETWGYLVFPKNFSSQMYQSSVLGSKVNLSVLTSRDIIGRLDETNKHISSASKQRFTKPNQILFQPCYQTVEWIQKIQSSLRYQKPIFGKDDTDMREYAAPNLSLTAAFFFPIISIGLRFIDEKKCGMMERSLVAGVKTWEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEU7</accession>
    <name>A0A1D2MEU7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001525">
        <property type="protein sequence ID" value="ODM91518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEU7"/>
    <dbReference type="STRING" id="48709.A0A1D2MEU7"/>
    <dbReference type="OrthoDB" id="6127080at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF3">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="275" mass="31639" checksum="3E0E5097D9E163BB" modified="2016-11-30" version="1" fragment="single">ISWMKRDEKNNLKLLTYGLVTYSSDARQSLHFESPNDWQLRLTAVQRSDAGSYQCQMSTHPPRILHYTLNVARINKTQARQVKKREQRRNYNDAILFAISDSEFCWQNGRRRMGKAHQLNDGDRLNCVSKENGFTSGFYGFQGGCFEAILFCMFTSSFPPFYPSKSFPGRSKSRFLSVLRITFKVLRHFETASKFWESSYCSNVAIIIIFPPPTCINADNISNNTCVTSGGENVAFRSTPVAQQDSQRSPLWTNKKVRNAHIQVSFCTTFEWKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF76</accession>
    <name>A0A1D2MF76_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Dual specificity protein phosphatase 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_15143</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 16">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001512">
        <property type="protein sequence ID" value="ODM91541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF76"/>
    <dbReference type="STRING" id="48709.A0A1D2MF76"/>
    <dbReference type="OMA" id="LYWNNFA"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000056">
        <property type="entry name" value="Dual specificity phosphatase 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848:SF4">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45848">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="11">
        <location>
            <begin position="122"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="12">
        <location>
            <begin position="187"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM91541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="436" mass="49221" checksum="5CDEDA33E5EE3C7C" modified="2016-11-30" version="1" fragment="single">FVSVFQNGDYSSSREPVSGNFFLCFLFPSAPTCNPATNGNETSSGSGEDSVKVSKSKIGATELVEGNQLKSQGRDSILMSDNTGSDITFGRQSSWRKRICERTRRSRSMEEDYGENSVDMTACVDLIEKGLYLGNKDTACDIRWLKHHSITHILTIDSCPLPTKITDLPFVKTKYLQVTDMAHEDILQYFEETNRFIQQSICNEVIPGNILVHCYYGVSRSATIVLAYLMHKYNISLEEALERVKSKREAIGPNHGFISQLKLYEKMGYHIDRSSPVFKRFRLHMAALKMKSVKVLPPPYTDVIRPDPALFSVRPEPVVYRCKKCRRILASGSNLLLHNEGKTPRWPEFLVEQDEATTSLCTQMHFIEPIVWMREAAHNLQGKLHCPNALCKSKLGSFSWVMGCLCPCGAKVQPAFYLVPSKIDRSNSVLNLQITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFC2</accession>
    <name>A0A1D2MFC2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001449">
        <property type="protein sequence ID" value="ODM91705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFC2"/>
    <dbReference type="STRING" id="48709.A0A1D2MFC2"/>
    <dbReference type="OrthoDB" id="8197657at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="560" mass="64391" checksum="597233209B39EA4E" modified="2016-11-30" version="1">MEFEFKVRRAVSLQGPLPLVLSTQLSKSLPNVTFECGCSKRPSQRQKILKKTWDRMKNMIGVESVKKRVPERNVVDNESERIRRNYALLQKRLSEELHARMSECKDKHHDNLSDEFRKRLMQWEMWKASTGKGQYTEEEILRNLPSEFGKKLIEWEWMKEGRKVCEEVGTLDWVEKNLEELRNEKRNLISRLRVINERESRLVRIRNAMKRPEGIWIKTPTGKCRVEKLTDEFAKKIYEWEEKRCVRAEFSTIALLDPKYYEHDKREAHSSRESVCSEDYDYQGGTRKSSSRSLTSEDDEEELLRKRAYKDAEAQTDVVLRAQAVVVEEDKENSTVFVKTNRTIFAPVHEEQMHSWKTTVVKQEQQRDHRDRPAIINAYKPQPKTQLTHKFPKRGGGGGKIPVWCSPLVARKQFACDQDYTIDSFLQKSSLLSQAARGSGAASAGSQESPDTSNRLQLPRKYTIGGGFPPCGSLLSRSNSFGFGRKSSALRVEPESSIGSSTMSVCSVSKSKSTGSISRKFGRVLFGLVGRRESAKGVVDDKMVPGTRVQCNDYHESRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFE6</accession>
    <name>A0A1D2MFE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosducin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001449">
        <property type="protein sequence ID" value="ODM91706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFE6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFE6"/>
    <dbReference type="OMA" id="INDGARW"/>
    <dbReference type="OrthoDB" id="70588at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.168.10">
        <property type="entry name" value="Phosducin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051499">
        <property type="entry name" value="Phosducin-like_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023196">
        <property type="entry name" value="Phosducin_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052:SF1">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="3">
        <location>
            <begin position="56"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19783" checksum="111BDCB2C28A737A" modified="2016-11-30" version="1">MERKMTTLDDKLLGERRENYCSSSEDEGERDEDDTPLASGGSPKVTKKIDINDGARWEGYSQNTGPKGVIRDWQLFKAHEEAKRKENERKLLEDVKKSSITCRPYSEDVDKELDELLQDDDDVLQEFINKRMETLLQSGLPKYTGQLHEIKHADEFLEIMITPKPPSLFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFK4</accession>
    <name>A0A1D2MFK4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">5-hydroxytryptamine receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_14906</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001424">
        <property type="protein sequence ID" value="ODM91776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFK4"/>
    <dbReference type="STRING" id="48709.A0A1D2MFK4"/>
    <dbReference type="OMA" id="NIEANEC"/>
    <dbReference type="OrthoDB" id="5956310at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004993">
        <property type="term" value="F:G protein-coupled serotonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071880">
        <property type="term" value="P:adenylate cyclase-activating adrenergic receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF199">
        <property type="entry name" value="IP13425P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="115"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="319" mass="35031" checksum="4B12D1F1399EA1AE" modified="2016-11-30" version="1">MIYWAVTDIDYIHQRSPQRILTMIGIIWALSLLISLAQRGFEDDKWEANIEANECVVNQELGYQIFATLSSFYVPLAVILFLYYRIYQAARKRIRRRRPPPAHTLLPRPAAETSLITQASSSNPSPEKTALLNNCGGGKNSTDGGTANANAGSSEGNNTTGGPVASAGIEGEWARECDKCSLFLQASNLSTSTAGVTPEVTPVRKTKKLRESGESKREKKAAKTLAIITGAFIMCWLPFFIMALVASACKSCNVSKNLMTLILWLGYFNSTLNPLSTPFSLPSFDSLSKRFCLGSSTGKVERSLCNEEKFIKTMILTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFR5</accession>
    <name>A0A1D2MFR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_14869</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001413">
        <property type="protein sequence ID" value="ODM91813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFR5"/>
    <dbReference type="STRING" id="48709.A0A1D2MFR5"/>
    <dbReference type="OMA" id="HYSTHIN"/>
    <dbReference type="OrthoDB" id="3561125at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000328">
        <property type="entry name" value="Zinc finger protein 1079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001156">
        <property type="entry name" value="Zinc finger protein 407"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000340">
        <property type="entry name" value="zinc finger protein 473 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050636">
        <property type="entry name" value="C2H2-ZF_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772:SF13">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="294"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="422"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="545"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="629" mass="73096" checksum="D1B826D1F51C5C5D" modified="2016-11-30" version="1" fragment="single">PSFHKLIWIQTYFARWCTRKANPKQGMQYLPKAFHEYGDLFVHIEDTRKRLSKSQNLYGHIRSIHIREKPFFCLECPLSFPNAHHSRTHTGEKPFSCLQCNSSFARANTLKVHMKRKHNIGDGVKCSVCSKEFPNSYSLRMHLNSHLNERSHSCLFCNKKFKSSSNLYTHYSTHINERPFSCKVCKKAFAFERNCTLHVETVHTTKKLHKCRECPATFSGTSYLQRHVKLVHRNIRPYPCLVCGKNCISNAHRTVHMTCHTNELPYKCDKRGQRYRRHCSLKIHLGHHETKTEHTCPKCSKLYFNQTDLERHYLIVHVDQNADILKCVFCQKVLKDRRRLEEHLSRHTKERHFCCYICSNTFYTEGGLNQHLKRHQNAMEKNGTSPVPKRGGFKRGGGRRRKDVAEEQPAPPQKLPGTLSFFTCDSCQYSTRHKGQLDTHMEVHKGSGTSQCADCGWNILPGNHNHHLKFCPYPYGLKERRCEASENTTYLKKFTTVNSAEIRHCCVRVKKLTQSEITRWTSSTSKLPISGLESVSSKKKARKEFKCAVCEKVFDNRSALSRHYSVHTGERPFQCPVCSKCFARKETVTGHIKVHTGEKPFSRNQPLRDGALIMQFRIDKKRFPSQLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHQ9</accession>
    <name>A0A1D2MHQ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Laminin subunit alpha-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14224</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001222">
        <property type="protein sequence ID" value="ODM92461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHQ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MHQ9"/>
    <dbReference type="OMA" id="HEHHMCD"/>
    <dbReference type="OrthoDB" id="10011303at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050372">
        <property type="entry name" value="Neurexin-related_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036:SF67">
        <property type="entry name" value="LAMININ SUBUNIT ALPHA-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036">
        <property type="entry name" value="PIKACHURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00054">
        <property type="entry name" value="Laminin_G_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Laminin G" evidence="3">
        <location>
            <begin position="223"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="3">
        <location>
            <begin position="497"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="3">
        <location>
            <begin position="677"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="368"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="825"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="855" mass="93723" checksum="A449A5684B9115D6" modified="2016-11-30" version="1">MGKEDVRFIISEEDQAGNVVDSVKDQYLGGNKAILNLNKNSSRLYVGGLPQGQARNPVKFSTFRGVVEDLQIGEEKVGLWNFKDSQNLSPAYETGGRVDKFEAGGKRGFVLGKDNGYFEAGTQSCVQEANWRSIAFQYDLGGDLTRGLLQQTESRITTAKWHTFEAARDGKNGVLSIDGQRKAQGKGRRVDHQDRLKVETGYTVLGCPSSSFAPSVASFFGQGYIQVSSAASPVEGPEIVTQDDTFEMSLRVRSNSSDGLILYGADNDQSNFISVSLVNGALHVKTEPGSAEIVTDPLNDADWHAVTITRDRGVLSVNIDDLHDYRAVAPDGPLNLATPGSTLYLGGRPEDYQPREDSGASNQQFSGCLSDINMNGKRVEFADAVKQDSSVSQTCSSLEEKKPVVTSTKTIPRDGSAELDGTPEPITPRPRPTPAPTPVEPPPEPESEEMEEVEEQEEEKEPMKEKLPEVAPTPLGQCQLPYRTLPGEEDVSMDEGARFGNLDKTSRLEYFQSEDEGIRSTYSIDFKSSNPDGVIFMWTEFDKIDFVALYLRRGHLHFGFDSGSGPAILNSSRLYNDSEWHSASFTRYKTQGELTIDGVVVATGNSSGSTTNVNAGTKLYVGGLPKEGWDKRMTLKKLQNVDTPFRGCLRNLVMRNKSPGQPTLKQSVYPCSSEVENGVFFYPNAGYLKLQDRFKVGRNIKISLSIKPRQPSGILVAVHGDRDFMILQLINGTVKFTVDNGKGPLYSSFTKEPYDLCDGQWHTIRVSKSKNVVTLALDNTYSSPGIGPAGKDSTNTNHPLYLGGHPNPNPAVTRGLETTDQYVGCIKDFVIEGRQFKFNHDAMQGTVGLHSCPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHS0</accession>
    <name>A0A1D2MHS0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14144</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001206">
        <property type="protein sequence ID" value="ODM92539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHS0"/>
    <dbReference type="STRING" id="48709.A0A1D2MHS0"/>
    <dbReference type="OMA" id="CISAESQ"/>
    <dbReference type="OrthoDB" id="10063861at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="221" mass="24603" checksum="00E9D463BA500798" modified="2016-11-30" version="1">MKFRAKSKDISSIQTFSQLLAALSHCSRKFVLRITPEKLCFILSDKEVSTATTSLLAWAEVPKDSTFLEYAMQGVSLEDNEIFLEISPEKIAGCLSSLKSSQSVEGLKIKLTKRVVPCLSFEIEFPGANLNGNATCVHDIPVDPIKRKFWHHYTELQIPAAFDITIQMPDLKLVRLALERMKNLGPRLLIKASSAGKLTLSVETSSVKCIVKFQEASFARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHU5</accession>
    <name>A0A1D2MHU5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin fusion degradation protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14212</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001221">
        <property type="protein sequence ID" value="ODM92472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHU5"/>
    <dbReference type="STRING" id="48709.A0A1D2MHU5"/>
    <dbReference type="OMA" id="NESEMYS"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000002">
        <property type="entry name" value="ubiquitin fusion degradation protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="79"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="5">
        <location>
            <begin position="181"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="365" mass="40551" checksum="7DA807346FBBEC6B" modified="2016-11-30" version="1">MADPNPPSPPENRDEDMDISDATATSDDDDDDFSFAEESLPEMEIPDMIPLARVVGPHRVLSHNQLRMAGLLFNDRSTFVQHYQVLSVGLLENRAHQHLENGGKVMLPPSALQQLYRNSTANMGPMLFKATNRMNQKFTHCGVLEFIAEEHLCYMPSWMMEILGATDHTMIQIERAELPVATFAKFQPQSVDFLEISNPKAILEKTLRLLACLTKGDMIAFTYNDKVYKLCVLELLPADAVNIIECDMNVDFAAPVGYVSPSAKEEDELEDTTGTAPIVVNGFVPFLGSGNRLNGKEAEASPSTTQRTKLLAKHAPDFEWKIGTLQYKRRFKKHSEDATTGADKKFSAFGGTGLSLKTTKKPVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIR1</accession>
    <name>A0A1D2MIR1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13880</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001146">
        <property type="protein sequence ID" value="ODM92802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIR1"/>
    <dbReference type="STRING" id="48709.A0A1D2MIR1"/>
    <dbReference type="OMA" id="PNQFRCH"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000688">
        <property type="entry name" value="zinc finger protein 197 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000193">
        <property type="entry name" value="Zinc finger protein 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM92802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="12959" checksum="A642C6789E43D6ED" modified="2016-11-30" version="1">MNTVNSIKKDAECPVCGKKFAKADSCMIHLRIHTGERPFKCSICGDTFALNSRLVRHSLSHSNKKQFQCEICPIGFNRPDALKRHVQAVHYKLRRHCCQLCGCRFAAISSAHSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJG2</accession>
    <name>A0A1D2MJG2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_13576</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001074">
        <property type="protein sequence ID" value="ODM93113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJG2"/>
    <dbReference type="STRING" id="48709.A0A1D2MJG2"/>
    <dbReference type="OMA" id="FRFIQRP"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000028">
        <property type="entry name" value="GTP-binding protein 1,-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000014">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="93"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="528"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="592"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM93113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="624" mass="67654" checksum="3E5B3DBFF7B4362A" modified="2016-11-30" version="1">MAGSMLVSPNEKEYDDLVSIIKNRVEEGNGETIFDVGDATEGGLTKDDFDASVATLQSIADSLDASMMQLRVRGNEKQTAQYLIRLKAPEQDFTEIRVAVVGNVDAGKSTLLGVLTHGELDNGRGHARMKLFRHKHEMESGRTSSVGNDILGFDHEGKVVNKAEHGSLDWVHICEKASKVITFIDLAGHERYLKTTVFGMTGHAPHFGMLMVGSNAGVVGMTKEHLGLALALSVPVFVVVTKIDMCPSNVLQETLQLLVKVLKSPGCRKVPVIVKTADDVVLSATNFVSERLCPVFQVSNVTGENLNLLKMFLNLLTTRSQHSDKDPAEFLIDDTYSVPGVGTVVSGTCLKGTINLNDVLLLGPDLLGHFQPIAIKSIHRKRMPVKQVRSGQTASFSLKKIKRSQIRKGMVLVSPSLNPTACWEFEAEILVLHHPTTISARYQAMVHCGSIRQTASILSMSKECLRTGDKAVVHFRFIKNPEYLNLNQRLVFREGRTKAVGNVSKVIPMVPTLSGGHGAKTKIIKNAPKNPFHHQNQSHQTNENVIPSSNGSNTAHKEESPDPATLPKRNSIDDELVASSLQPQVGQGGVGQKRHNGKRGGRRKHTGASGSGGAGTGPLAESNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKF9</accession>
    <name>A0A1D2MKF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoporin NDC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000979">
        <property type="protein sequence ID" value="ODM93460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKF9"/>
    <dbReference type="OMA" id="VDENCER"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="652" mass="74566" checksum="AC41C4C9E10F4EE6" modified="2016-11-30" version="1">MGSFRTSTLPDWNLYERDGYFSSRTPRVSEAPSSQPQDKVPNVSATQLKYNFISKDVKQAEFQVKLSRLANSMWLACGWQMILFAFFSLLFIQPNNSTKTESSLLLYYFGITYLSSVSQTFVFSLISLSTLLLGVLVYFQLFMVATCLTSSEKYAESIKDQVSRYTTFRFLLKPLCFGAAAWAQCFIFVHLFDQSYENLFVAKEVSDGFTITYVQENLLVLRLAAFFTGVEFFIDNFLSGGFRLQFPSTRVRWSFSSVIRIDETLNNVKGSVYLALLVWIVSLLLGPLLYSPLFTAAGVQIFQPQVLERFFMFLDIKFMFRLLLWVYVPRLTLRLYLQLVNSFFTEIINFPIESPPNNSKCLTLSEGMKCDNAYLKCQAFYEFKLKARLGHQTSWYFSILPTSSKVLADVNDNMISFLRGAVLPSNILQGGFQPDILNKLRRDFPPTTSPVSAETLPENLKTATMRDLTSHNNPVAPDGPTVYDLVKQMPKALWNDLRDACKGLVTMQNLNNLIFFGKFETKLQEKQIANYFSQGTLSFWALEGTLELICISVTHDPHGIVHQDLQSFFKTVVETHDILSVLDFYVINTLDREDVNRQILEEVKIVIGKLLSATVFVLAKLNASFSHCYRILNVDENCERRILEIITARDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKG1</accession>
    <name>A0A1D2MKG1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Oligopeptide transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13170</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000965">
        <property type="protein sequence ID" value="ODM93509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKG1"/>
    <dbReference type="OMA" id="SITIMDF"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17347">
        <property type="entry name" value="MFS_SLC15A1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000049">
        <property type="entry name" value="Solute carrier family 15 member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="702"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="735"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00078114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM93509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="756" mass="85036" checksum="B931D39DE2AD7FF7" modified="2016-11-30" version="1">MSDDGEMKVVRRNSVISSSEKDGNQKPAPGQTTDFESMMEKIPYPKAVFFIIVCEFCERFCYYGMRAVLTLYFKNALGWNEDFSTVIYHVWVMLCYFTPLLGAMLADSFLGKFRTIFYLSVVYCTGSIVLSVAATPPLHIPTVAFSLIGLALIALGTGGIKPCVAAFGGDQFQIPGQESQLESYFAVFYFSINSGSLLTQIVTPIFREDISCFGDDSCYPLAFSVPAALMIVALIIFLVGRPMYKIVKPQGNIVLKVMSAVKHSFSRRGKEIKAGKRREHWIDYADDKFDQRFLNEAKVVFKVLFLYIPLPIFWTLFDQQGSRWTFQATRMNGHIAGGFGIKPDQMQVANPILVLAFIPLFDRVIYPLLAKVGLLKKPLQRLAVGLFFAGVSFVVSGIIELTLVPTYAVELAEGESNLHFVNALPCQIKIAGTGIGEAQILPNEMFIHEAIGTKNYTVQIDIEGCPLYMDVEDQYEITLKSQNATTYVAYLGKGVNPDDPRSSIVRLEQSDLPDELEKSENGDPIFRVIWFGFDDAGDNIEFKAESEKHVIRFKGEGPQGATESREIEPKMYWLSLVADNIPNGVEFVEGMDLELGGSYLTTVIRNYTVEGDGTDPSHYAVARHEITSPNSVHMLWLLPQFVIMTIGEIMFSITIMDFSYTESPPNMKSVMQSAWLMTVAFGNLIVVIIAEAKIFKEQYKEFFLFAGIMFVDLMIFAYMAYRYVPTEKFWLKDHEKKDEDTKEKSGKDNDGFDRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKM3</accession>
    <name>A0A1D2MKM3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative leucine aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13218</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000978">
        <property type="protein sequence ID" value="ODM93465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKM3"/>
    <dbReference type="STRING" id="48709.A0A1D2MKM3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904183" evidence="9">
        <location>
            <begin position="18"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="122"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="41855" checksum="6563AD4D725D7E19" modified="2016-11-30" version="1">MDFKCLLILSLLSTSLADPPEEQSSNTPASAKAREYEFIYSENPLQQKHLVHKLFPQLDRTSLKESVDTLSSSENRAKTPNDDGASILEDSIRKLLAKYEGGSVFFNKIESSSSPKSYLTPNLIASFEGKDLLVKNERVILSTHYDRVPVSRGADDNYSGCAVHLEVLRLIAKFSLKFKHTVELHFYAGNRAGLKGSADVARKYQEDKIRIKGLLNLDSVGNYASKYGRVLGLVLRLEIDGKKVESPPSFEAFVKKLVKEYSKEPAVELECNNRGCNSDHLSWHERDFPWAFITEVEASPNIDTEKDIVDEVDFEQVVEFAKVALAFVIEAGELAEVPEIEHHSSSAVGFLKPELGWIWSGLACLAAVTAGLLNYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKZ3</accession>
    <name>A0A1D2MKZ3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apolipoprotein D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000933">
        <property type="protein sequence ID" value="ODM93690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKZ3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904200" description="Apolipoprotein D" evidence="1">
        <location>
            <begin position="25"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21150" checksum="6BC1038187AFB8E7" modified="2016-11-30" version="1">MANNYLKFLKLAVLFSACIVSANGLCRPQLPKYNFDLERFLGSWKIILTGFTGVPPPSAQVEECVIYNFTKTDSPDTLGYGYQHKVNGSWLVTNEGYAIVMDLEMPSIFDIRANRGSYITSVIHTDYDSMLLLSACRDDEEQYYIGSRQETLEPVPMTILSDLMAGFGNLTETRPIFHQGINCIPPVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML92</accession>
    <name>A0A1D2ML92_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E2/E3 hybrid ubiquitin-protein ligase UBE2O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000935">
        <property type="protein sequence ID" value="ODM93672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML92"/>
    <dbReference type="STRING" id="48709.A0A1D2ML92"/>
    <dbReference type="OrthoDB" id="47801at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="621"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="856" mass="97243" checksum="28A7C33E9082C825" modified="2016-11-30" version="1">MSVKSDDDTSLSGGSSFRSAASSRGSQLSNRSSSSFQNNNVHSSTSLDNHDQDKCSRHCLSLSPCFCIRSFYEDDEVCRKNAHGNLEFGIVSRYENTSDLKVFWTLDNEIEEQDLDYNNPQKHDNLRLIDRKLEPGDTVHCGRKRGEVLDVSWLCYLRILDNGMGLLDIPCERLEPLLPYYPGQRIEMNGWIGTIQSISTEANLMFPGGKTAIVDCQGLPKDQQPYPGSRVKYSFDELNEAGLDHIDGETLPQIFNEDPVEAFVLFLNISAVGVAWNGRITGYPNSPAAPSMPNNYLSRSQLKKHVKILGMQRDVDWDSNPEVVDRLYNYTVRPTDTLITDSRTGIENHMVAKYFNNSEHDQSTKSLEALQRDELVGNVSYIVRVLRFGRVLRVKWARSGKVERIRASRITSKHSFQQPFRQLVQRKISLCPYTQDEYGVTLTRDTNDTVSVQWLGKDSLDSSSFRMIAQTSESTYDLEPHFVYGSIKPKEIVYRSAHCRLPDPLFTVGWVRQITLQGQIIVVSLQTKQEHSVFPTEIDTTGMKINSDVSEHKIGRPSVDMIRLHGLSILRMADQYFTMNVNKLMDWTCAVPQSQHFKLVTKAPTTHAFYQNQFAARADGHWFRAVRNDQITLNTQANETLGTVWIKGFGDRLDLFSVLMAAPVGTPYEGGLYTFDVQLPYEYPIAPPSVYLTTVLSPSSKIRPGIHSLELVDAVPPHSLVESLMTLQAKLFSSSSESLELPSSAASLHRREFSLNEKQESRTNAQILIDTLDLMFRMAMDPPKLWSEEVIRHFHMTFPRSKSRLTDLIELREDPYSKPSSEWAIPHYPLLPLSDGFVDAVINRIKRFEQLLQRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLZ9</accession>
    <name>A0A1D2MLZ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine aminopeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000867">
        <property type="protein sequence ID" value="ODM94059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLZ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MLZ9"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904236" evidence="1">
        <location>
            <begin position="17"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="128" mass="14496" checksum="018538D34A8ADC70" modified="2016-11-30" version="1">MKVIAFTLLFAALVAATPVQNGSKRLILTGVDSPAVWLSEQEIWKLIENNQRFIDITGQSETPVLAQHTRAIPTTLKFQSVVSRLVGNINRPRVEEFVRDFSSYRTRYYTSDTGVQSQKWLLQQVQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM03</accession>
    <name>A0A1D2MM03_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000891">
        <property type="protein sequence ID" value="ODM93905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM03"/>
    <dbReference type="STRING" id="48709.A0A1D2MM03"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="22837" checksum="2ED1628CB3034402" modified="2016-11-30" version="1">MPRLNSYHLCRSEERDPPHRNKTSVTEGQRQHTQNGVLWFLPYAITKIIRAELTNHLKKFQGKILCQNFIQMDKLIISLAFMAIVGVVLAYPADHREDTVLPFSLSPGNVNLETYYSDKYPGPNPAKQAPPEENMFAEESEPELKFRSRREANPQHHHGGYHHDQGHGHYNPPTYHNQPQYGHHHHQNTHGHHHHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN94</accession>
    <name>A0A1D2MN94_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vascular endothelial growth factor B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12377</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PDGF/VEGF growth factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000828">
        <property type="protein sequence ID" value="ODM94305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN94"/>
    <dbReference type="STRING" id="48709.A0A1D2MN94"/>
    <dbReference type="OrthoDB" id="8878063at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070851">
        <property type="term" value="F:growth factor receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051781">
        <property type="term" value="P:positive regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008284">
        <property type="term" value="P:positive regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000072">
        <property type="entry name" value="PDGF/VEGF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11633:SF1">
        <property type="entry name" value="LD28763P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11633">
        <property type="entry name" value="PLATELET-DERIVED GROWTH FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00341">
        <property type="entry name" value="PDGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00141">
        <property type="entry name" value="PDGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50278">
        <property type="entry name" value="PDGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0339">Growth factor</keyword>
    <keyword evidence="3" id="KW-0497">Mitogen</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904313" evidence="6">
        <location>
            <begin position="22"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Platelet-derived growth factor (PDGF) family profile" evidence="7">
        <location>
            <begin position="222"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="386" mass="43472" checksum="A4D19FEF6B6FC23F" modified="2016-11-30" version="1">MKGSLLLTLFVLLSYFAVSNQQMAHGVTTPSNKASRAIDDNSRGNNQILSNNDEDSDNTDSAFDGSPGDDSEITFPSESPSLPKPNIKARAQYNPSRWRKIPLKTLVEIGNETNISNFLRRYLQNARVKKDPETNEEYLIDRDNNTLYNTRDEKVIVTPGRQLSSDPQPIFPSPGLTRSGAGIATRSRAPTIFNANDISGMKAKQDFAFAVCTPEVKTIPVPLEVEPHILIIPRCLRVERCGGCCLSDVMSCEPEKTEMADFHIKTLAYTGDDQKFDFVDDRIVNIERHLSCKCQCKTKKTDCNNVLHDYVENECSCSCKNRTDQEQCNRDPKKVWDENNCMCLCRETRSCSSGLYYNLNDCACQREPELRRKKKKRGAPVTLSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ28</accession>
    <name>A0A1D2MQ28_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 9e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_11570</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000709">
        <property type="protein sequence ID" value="ODM95126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ28"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ28"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM95126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="32960" checksum="8CAF5641B28FD31D" modified="2016-11-30" version="1">MDPASSSTQNDEITHLTIDVIAVSVFGINGRTIQDPKSIFSQMCHRLSDFNLLRTVKIIFSMNFPWLTDLIGMEVMDGARKGVLKGVGADELSSFEKEAQLSEGVKGKNNYLDDDTIAHAQLIAFFFAGFTTTASIVTFAAYALAAHPEVQEKLREEVDKKLFKDGDDKEIDYDELNKLTYLDMFISEVLRKFPPLGRLERKCVKEYHDPESGPEIKAKRNPYCYMPWGMGPRNCIGMRFAKIQVQSAIVRLVHSFNLETTENTPLPMKAKAMGFAIQPPDNLELKLTPRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSG0</accession>
    <name>A0A1D2MSG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diuretic hormone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000602">
        <property type="protein sequence ID" value="ODM95956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSG0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000187">
        <property type="entry name" value="CRF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00473">
        <property type="entry name" value="CRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00039">
        <property type="entry name" value="CRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Corticotropin-releasing factor" evidence="4">
        <location>
            <begin position="121"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="167" mass="19105" checksum="907968B962F4E333" modified="2016-11-30" version="1">MQSNLETFGVIHHHCCTQSNLLGPNTEDCWKSPLKIMLVLFSFNVTSCSGINNLWKHRSTRRNWKCLSIAVTLCLLVSMTDARPAAAGSKSLRDHSRYFFVQSSTSNYMAQNSVNTDTSSSSDTLSIFSPLDVLRQNMLLEIQRRRIRHAQHRQVKSNKEYLDRIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT34</accession>
    <name>A0A1D2MT34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">1,5-anhydro-D-fructose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10614</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000586">
        <property type="protein sequence ID" value="ODM96061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT34"/>
    <dbReference type="STRING" id="48709.A0A1D2MT34"/>
    <dbReference type="OMA" id="RTNSENC"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000006">
        <property type="entry name" value="Aldo-keto reductase family 1 member A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM96061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37610" checksum="35C3E80CD6551CA8" modified="2016-11-30" version="1">MSIKLSNGHNMPLVGLGCSVFPEPPSVVEKAVETALDIGYKHFDTATLYNTELHLGNALRKAFDAGKVKREDLFIVTKLPQNAMAPERVSQFMDKALRDLQLQYVDLYLVHWPVGMLYRGNEKEMVPVDGDGNYLYDANTDLEAIWKEMEKLVESGRAKSIGVSNFNEKQLERILKIAKIPPVNNQVELHAYLQQPQLREFCNKHGISLTAYYPLGGLSRKDYPAKLKITVAPKLLEDPVVLDLAKKYNRSPAQILLRFSTQLDVAVIPKSSNPSRQLENFQIMDFTLKNEDLELLKSLDQGESARSCFSWPGAEKHPEYPFGHARFVPPPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTH8</accession>
    <name>A0A1D2MTH8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000541">
        <property type="protein sequence ID" value="ODM96410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTH8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="27931" checksum="178010A0C57DB310" modified="2016-11-30" version="1" fragment="single">GDENSSSSDSGCETDEAAGSIDIYTDEDIDDVSPVLVSYKSQSNSLESIPIVVGTQIIRAGNFKTNNRSADDDKQLKTTLNISFDGLEMVAVLDEREYGDNVIQCGFCSFNSPIPSKGCGAFIDRVVAMMDVDHHCKIKHPLAYCASKASKQGSLPKPQPKGKVNKEMSKMIRPPVKSGRPRGRPPKSKKDDENRKILPSPISRCSEQRRPDGEKKATFSRLANDDAKKSTNPISYGGFGVSIEEKVKLFGRRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVH4</accession>
    <name>A0A1D2MVH4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acetylcholinesterase</fullName>
            <ecNumber evidence="2">3.1.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09676</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>acetylcholine + H2O = choline + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17561"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="EC" id="3.1.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.7" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000479">
        <property type="protein sequence ID" value="ODM97006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVH4"/>
    <dbReference type="STRING" id="48709.A0A1D2MVH4"/>
    <dbReference type="ESTHER" id="orcci-a0a1d2mvh4">
        <property type="family name" value="ACHE"/>
    </dbReference>
    <dbReference type="OMA" id="FADEWAN"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003990">
        <property type="term" value="F:acetylcholinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006581">
        <property type="term" value="P:acetylcholine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019695">
        <property type="term" value="P:choline metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000029">
        <property type="entry name" value="Acetylcholinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000997">
        <property type="entry name" value="Cholinesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF13">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00878">
        <property type="entry name" value="CHOLNESTRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0531">Neurotransmitter degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904618" description="Acetylcholinesterase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="13">
        <location>
            <begin position="137"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="671"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="671"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="10">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10">
        <location>
            <position position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600997-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM97006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="788" mass="88100" checksum="934DF63ED8E7DA3D" modified="2016-11-30" version="1">MRRRLILVVAILVFSACVSSSVGRRRTRRPPTGFGRQSEYQQNQYGQEQDFGDIGQSQDYQRSNNPLEYGGLQQSNQLHYDDDQGDIQQVSQDTEDFSGLTEEGLLQQNQIGGDEPPPRYTQGDESSEVITLKTRPEAVTPKGEFVGLKQTVNGVVVYAFYGIPFAKPPTGDLRFRRPEPADKLTDSFDASHLPNACPQTVADIFNNFRGEQMWVPNTNVSEDCLYLNIWVPASVFELKEEELVPVIFWIFGGGYFSGSGSLDVYNGAVIAATQGLVVVNAQYRLGPLGFLYVGTEDAPGNMGLIDQSLSLRWLRENIEYFGGDPNAITVAGESCGAASVGFHLVSPLSKSYFKRGVMTSGLPNSEYALKSPDELKARSIQLAKLAGCKSKDTKEVIECLKKVDAETLVALQWKLYKNMLDFPFSPTVDGYFLTDHPDNLIKNGKAKRAELILGTVQDEGTYFILYHYLTYFSHLKPTSVPYDRFVDILNELFHDHSEIEREAIVDAYTNWENPEDGYANQKLIGEAVADSVFVCPHRKFADEWANRGLSVYYYHFTERLRSNPWPKWMGVMHGDDIPLFFGEAVTNSTTLYTEPEKQMSLKFMNMIANFARVGVPSNKWERYTSEHPVYLNVNATTVTDASTPDLHGPRSKECVFWNKVLPTIRSATQQCNNQLPPNQFGSLRQPQEQPQVPQWNPNGQGIHGGQGFHQPSQQQPYCGTSYPQTPAYYPPPPPPSQQYRASNGCNPPAAAPTPTAQSCECTVREGVTSTPRYEQDVDDLSTPPPAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW40</accession>
    <name>A0A1D2MW40_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_09529</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">In addition to its role as an aminoacyl-tRNA synthetase, has also cysteine persulfide synthase activity. Produces reactive persulfide species such as cysteine persulfide (CysSSH) from substrate cysteine and mediate direct incorporation of CysSSH into proteins during translations, resulting in protein persulfides and polysulfides. CysSSHs behave as potent antioxidants and cellular protectants.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Mitochondrial cysteine-specific aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 L-cysteine = S-sulfanyl-L-cysteine + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:78543"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58591"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:78544"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>S-disulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:78651"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:19120"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:229465"/>
            <dbReference type="ChEBI" id="CHEBI:229521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:78652"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>S-sulfanyl-L-cysteine + L-cysteine = S-disulfanyl-L-cysteine + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:78627"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58591"/>
            <dbReference type="ChEBI" id="CHEBI:229465"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:78628"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>S-sulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-sulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:78647"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:19119"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58591"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:229520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:78648"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="18">
            <dbReference type="Rhea" id="RHEA:17775"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000468">
        <property type="protein sequence ID" value="ODM97151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW40"/>
    <dbReference type="STRING" id="48709.A0A1D2MW40"/>
    <dbReference type="OMA" id="CSAMTHH"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF27">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 21" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="20">
        <location>
            <begin position="83"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM97151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="585" mass="65647" checksum="6F5C07D12DA3C0AF" modified="2016-11-30" version="1">MLFPTVRVGLAAACGCRSYKRKAVNTHRSVGRLLFSSGTSLQEEPATKISPESLYDSSKALYNTPFVIFDTAKNGKCKLSTRRPNILTWYSCGPTVYDSAHIGHASSFIRQDVIRRILESLDKDLTIIQVMGITDIDDKIINRANQTGKEWNSVGKHYEQEFIEDLKNLNVIQPHIFTRVSDYIPQIIGFVGNLIKGGYAYPVSDGSVYFDTEKFGSRYGKFRQANSDSQEDEEDGTEFAGGKKSAKDFAVWKGAKPGEPFWESPWGTGKGRPGWHIECSVMATQIFGPNLDLHTGGKDLIFPHHENEEAQCCAHFDSSSWTSHWLHMGHLHFKGDVKMSKSLGNTVSISNFLIDYSPDVLRIMCILSKYRKNLEYSQDSIDNAKKVLKKFHTFANDTSSILDGSKPVNTTAEDAALWTKLESARTHLKASLLNDFDTPEAVKTLMEFISDFNRHHIPHDSSSSSSSSTNSNVSYELVLASRIFALEFLNLVGFQEFTLDSRKSKGGGGHEIPYENLVEKFVQFRNQVRSYSLALNEPDKQLRKQKIGERAELITACDNVRNQLLAENGVEIKDHGKSSSWSFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWW2</accession>
    <name>A0A1D2MWW2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_09147</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000434">
        <property type="protein sequence ID" value="ODM97533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MWW2"/>
    <dbReference type="OMA" id="LEFNTHG"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000097">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="14">
        <location>
            <begin position="154"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="88"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="12">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="12">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="12">
        <location>
            <begin position="222"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1068"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1213"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1084"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1112"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1149"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1223"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1242"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM97533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1314" mass="145084" checksum="566B8B9B91C848DC" modified="2016-11-30" version="1">MALVIGGEKVTMDSGDESGQSAFKFFDQGYGQSQSQTGFAGGGGGGGSGVNGFAFQEFGTTQSQSQRMDMFTQRDLLTQAGSQFTQLTQPDGEFCSQNDGGGDADRVRHSSSSSSSSDNSRSHGDNKSSIEEDDISRGLEELRFEDDDDEGTIFKKLPDHACRYCGIHEPSSVVQCNICDRWFCNGKGLTSGAHIINHMVRSKHKEVSLHKEGPLGDTVLECYSCGTKNVFVLGFIPAKNDTVVVLLCRQPCAAQAALKDENWDYNGWRPLSPTAASWTGLVKVPTSKEQERARQISNTQIVKLEEIWKENQDASFQDLEKPGIEDEPQHVLLRYEDGYQYEQIFKPLIKLEAEYDKKLKESQKHDTVDVRWDVGLNKRTTAYFTLPSIGDSDLRLMPGDELKIRHNGEKYKNWNGVGHVIKVPDNFGEEIGIELKLKYCHNAPTEMTSSFVVEFVWKSTSFDRMLAALNKFAVDDRAVSSYIYHKLLGHEMEEQLFRLQLPKNFSGKNLPELNRSQAFAVKHALQRPLSLIQGPPGTGKTVTSASIVYHLAKINGGPILVCAPSNTAVDQLTEKIHQTGLKVVRLCAKSRESIDSSISFLSLHNQIRKLSQEVCMELSKLQQLKDETGELSVADERRYINLKKKVERQILEVADVISCTCVSAGDPRMSRLKFSSILIDESMQATEPECMVPVVLGAKQVILVGDHCQLGPVVISKGRPLSILFERLVVLGIRPFRLEVQYRMHPDLALFPSNYFYEGTLQNGVGSKERTLMVDFPWPEPEKPLMFYVTMGQEEISASGTSYLNRTEAANVEKVTTKLLKAGIRPEQIGIVTPYEGQRAYLVQYMQANGALNTKLYLEIEVASVDAFQGREKDFIILSCVRSNDQQGIGFLNDPRRLNVALTRAKFGLIIVGNPKVLAKHQLWNHLIRYCKDLNVLVEGPLTNLKECTLQFPKPKKMTNAVNPGAHFMQTNMYDARDAQQIPGPPGGGQHFGGPPNQLNANVHGFIPPMPAYYNNMRQMYDPPSEAEFSRISEEFSYINQQNLQFQNSFPVPMGMFLNMSHIPSRFFNQPDQEHGQGAFNHNMGGGPPGRGPMGASRMPQNPSGPGFNRNKGGGRGDQMFPSGGGGGNKNMRGPATGNRTSGKGYGSEMQSQPGMLSQGYGLSQNEPGGSSSQSFGTQPMTQPGAFGFGSGMSQGNMMSQQEFSEDYGMEFQSQSDLPFGPEFERGGKPKTDGGFPDNLFPGGGASGGGSGKGSGGMSQGLQFSQIQYLPILSGSLHHEELNGYRETKKMRMMITHKRGEDGVNKAEDKLMVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXS1</accession>
    <name>A0A1D2MXS1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cadherin-related tumor suppressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_08857</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000407">
        <property type="protein sequence ID" value="ODM97827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MXS1"/>
    <dbReference type="OMA" id="AQISYLF"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048589">
        <property type="term" value="P:developmental growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001736">
        <property type="term" value="P:establishment of planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000104">
        <property type="entry name" value="cadherin-23 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000321">
        <property type="entry name" value="Cadherin-related tumor suppressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000020">
        <property type="entry name" value="Dachsous cadherin-related 1b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000015">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000276">
        <property type="entry name" value="FAT atypical cadherin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000024">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000039">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000143">
        <property type="entry name" value="FAT atypical cadherin 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000007">
        <property type="entry name" value="Protocadherin alpha 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000081">
        <property type="entry name" value="protocadherin Fat 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000134">
        <property type="entry name" value="protocadherin Fat 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF438">
        <property type="entry name" value="CADHERIN 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25374">
        <property type="entry name" value="Cadherin_FAT4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904716" evidence="14">
        <location>
            <begin position="30"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="88"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="143"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="257"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="374"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="481"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="586"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="694"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="798"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="923"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1019"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1123"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1233"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1358"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1463"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1579"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1678"/>
            <end position="1800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM97827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1817" mass="199394" checksum="63F8B86659AF82DA" modified="2016-11-30" version="1">MMQPWRRPPVASVYAVILIHLLLIGNAHSINGGSKDRLTRRTSSATARNVDMRVEFEVEEGLPAGTFVGRIPTRPGYTYRFNENVDKFVLNGSTGEIRTSREIDREALTSDRFDLVILSSQPTYPIEVRIVIKDKNDHAPVFPEPEVSVSFPESASAGTRVFLDTAEDPDANENGVTTDYKICDGNEDEHFRLVVTTNPSGEAPFLHLETTGKLDRETKPTYKLNISAQDGGNPPKQGFLIVNVSVNDVNDFQPVFSHSQYSVSLNDSVPVGTFVLQVTATDNDEGTNAKITYYLSETETQFAIDPETGVISTAQQLNCQQNCPQGQTRNCPKSCVFTVFARDHGIPRQDGRTYVTVILIESNHAPVIKFRYFPPTASAANVLETATNGSVVSAISVVDLDEGPNGETVVEIVSGNELQHFRLESTPSFQLIRTNAVLDREKISTYNLTITAIDNGTPPCSSTAYLIIEVNDNKDAEISFAKTEYSAVLRETVPVGSYVASITATDEHVASKSQVIYSIVSGNEKMWFHIDPNSGLLTTRAQLDREVQGTVRLKISARDGGPYPKWAHAQIKITILDENDEKPQFASEKVDVTLAEDVAPGSLITTLTATDHDQGTNGSVIYSLSPITMLKYPDMFHIDSSTGKLTNTGRCDRETRAEYGIQIIAKDQGTPALSSTASVLLSISDVNDNEAKFYPLEYFITVTEDTTVGSSIGQVIAKDPDEGDNAIIIYKLEPPSTPFFAVEENTGKILLRASLRGIKTKQFHIQVSAMGNDGKKSQENAAVEILVEMAGSNHLKCSKDIYSYSISENRGNKNSPSSPPSLIEHRDVGKIELDPRTINFSPVSSIRYTIMDGDPQGIFAVDDASGLIKAVKEIDRETHSYYTLTILARKGLTHGTCFAHIKILDLNDEIPSYWNLSQLDTIIDANAPIGHEVLVLKATDKDEGRNAQIMYTLSRNPGEIFEINATNGLISLQKSLRQTPLTQIELEVTASDNGTEPLSSKQNVHITINPVNEHTPVFEHSSYETSLPETTTVNTRFYMLQATDQDTGVNSQLDFEIVEGNKAAKFGVFPDGALYVKSRLDREDQDYYSLIVQVSDKGTPQRSSLTSVVIHIIDENDQAPKFTNSTFSFSIPENEAAGTYVGKVSATDGDIGRNAELTYSLVPQSQNDFTIDPKNGFIKTLKSFDREKLLQKTGQPFINLDVMVHDNGVIRLKDKAQVVISITDVNDETPKFLKSAYTAQISEDAAVGSQVIRVTASDIDEDLNGDIIYYIKEGNEGEAFKVDVTTGQITLEKQLDRESRDRYILQIVAQDMAEKHSLSSSVSVTIDVLDVNDCTPTFLPTFTRLSEKGSLNQTEKIISSAAGISVVEITPVNTELAKFAANDCDIGLNQRVSFSITGGNRHDTFLMNAQTGSLLLHKPLDFEKYTSYALNITASDAGNPRLSSSITFTIKVNDYNDNAPVFPSTSIVRQIQEGIPLKTPIVTVSAEDPDSGINGKVKYSIKEQDPPGNHFGIDTDLGSIHTLKDIDREFADTFRLTVIAVDQASPESLRLSSEKLVTVIVEDINDNEPKFVCMNAAVLSKNSPASTEITKVLATDIDSESNGAVTYDLVSGDNGMFRLDRNTGSLTLTRTAIDIQPRYQLTVRATDEAIQSQRKSSELYLMILSVSDKSSVNGLTFDQPMYSGSINENEPIGSSILTVSASLGQKSFLSTDTSGSTSVEYYITNITSPDGILQNRLFDMDVKRGTLSSAAILDREMGVWDFQLEIYAILVSAQGLTTASTKVKPTLCNTLVKLLFFPSFWLSHNILSPLSHFKWTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYB2</accession>
    <name>A0A1D2MYB2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pro-resilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_08653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000388">
        <property type="protein sequence ID" value="ODM98029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYB2"/>
    <dbReference type="STRING" id="48709.A0A1D2MYB2"/>
    <dbReference type="OMA" id="KYEAYEY"/>
    <dbReference type="OrthoDB" id="6418165at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF98">
        <property type="entry name" value="CUTICULAR PROTEIN 56F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904731" evidence="3">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="11978" checksum="91C5880505E8184A" modified="2016-11-30" version="1">MRAQIVFVGLLFAILGLATARPQDAEEKSEPMPYNYNWEVNDEESKSYYGHEEKGTEAGRTEGKYFVWLADGRLMTVEYYVDGESGFVPKITFSDPNFSPPAAAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYI2</accession>
    <name>A0A1D2MYI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongation factor 1-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000417">
        <property type="protein sequence ID" value="ODM97715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYI2"/>
    <dbReference type="STRING" id="48709.A0A1D2MYI2"/>
    <dbReference type="OMA" id="KCGFIEL"/>
    <dbReference type="OrthoDB" id="331763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005853">
        <property type="term" value="C:eukaryotic translation elongation factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00292">
        <property type="entry name" value="EF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.60:FF:000001">
        <property type="entry name" value="Elongation factor 1-beta 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018940">
        <property type="entry name" value="EF-1_beta_acid_region_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049720">
        <property type="entry name" value="EF1B_bsu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001326">
        <property type="entry name" value="Transl_elong_EF1B_B/D_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595">
        <property type="entry name" value="EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595:SF26">
        <property type="entry name" value="ELONGATION FACTOR 1-DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10587">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01182">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="eEF-1beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00824">
        <property type="entry name" value="EF1BD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00825">
        <property type="entry name" value="EF1BD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Elongation factor 1 beta central acidic region eukaryote" evidence="7">
        <location>
            <begin position="179"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange" evidence="6">
        <location>
            <begin position="214"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="300" mass="32775" checksum="3DD93932A63152DD" modified="2016-11-30" version="1">MAKCGFIELVDSFAFTIDTLRYAAAEQRYREFLSSGGGERLQSCQAKSHGSERVDPGAKKVASSDTQATTTTTTASSPASGLKALSQQIEQARLQIQSSLKNGPTSISGGVAPSEDDAAMREENLRLKKQLEDLQNQVRQLTDRVTRLEGAVKVTGPTAPIKESGGNKKAADDDDDVDLFGSEDEEDTEAAKIREQRLAEYAAKKSKKPTLIAKSNVILDVKPWDDETDMKELEVSVRAIEMDGLLWGASKLVPLAYSIKKLQISCVVEDDKVSIDELTEKIQENEEFVQSVDIAAFNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-11-27" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYX9</accession>
    <name>A0A1D2MYX9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein Asterix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_08474</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Asterix family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000373">
        <property type="protein sequence ID" value="ODM98212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYX9"/>
    <dbReference type="STRING" id="48709.A0A1D2MYX9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005351">
        <property type="entry name" value="ASTER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13193">
        <property type="entry name" value="CGI-140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13193:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT ASTERIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03669">
        <property type="entry name" value="ASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM98212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12195" checksum="D0336EC30D357DB5" modified="2016-11-30" version="1">MAAVPSSGNKRSERIKKWESYKNDMNGNPVSILDEPTVAFDTYMLFGMMFGILGVVIQVKMMAWVACYCTLFCASNYRSQADLRQLLSCFLVSGMSLLMLYSKDPSPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ84</accession>
    <name>A0A1D2MZ84_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Suppressor of cytokine signaling 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000364">
        <property type="protein sequence ID" value="ODM98322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ84"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ84"/>
    <dbReference type="OrthoDB" id="6426624at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005942">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046935">
        <property type="term" value="F:1-phosphatidylinositol-3-kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009968">
        <property type="term" value="P:negative regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10388">
        <property type="entry name" value="SH2_SOCS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03741">
        <property type="entry name" value="SOCS_SOCS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035866">
        <property type="entry name" value="SOCS7_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037346">
        <property type="entry name" value="SOCS7_SOCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001496">
        <property type="entry name" value="SOCS_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036036">
        <property type="entry name" value="SOCS_box-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10155">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10155:SF5">
        <property type="entry name" value="SUPPRESSOR OF CYTOKINE SIGNALING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07525">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00253">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00969">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158235">
        <property type="entry name" value="SOCS box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50225">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0341">Growth regulation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="2" id="KW-0734">Signal transduction inhibitor</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SH2" evidence="7">
        <location>
            <begin position="707"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="SOCS box" evidence="8">
        <location>
            <begin position="808"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="446"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="613"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="551"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="617"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="645"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM98322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="877" mass="96224" checksum="F22F532921CFA0B7" modified="2016-11-30" version="1">MRRGDGDEFVTISPPPEFQDPVTLPPPPVFRDGAQLDNLDSVSSSNNHPSVAQASSDTPTEKICVTDFASKVSSDILNKAMVIAKDSPETPTAENSDISVICQSHDTSNPCTCSTAPRTATSWEYVSKSSSLSDLTQFGAAFVTSRHHEITPSLLSSSQTNTHTGRSLLPHGVVPLPPPHRSAPNGYRLSQKDLVQQQPSVDGSRRTPTSSRCTSTKDDSNPVMRSASFNLEYAGPRRTNLSRVRSHVSSSSHAFTPSQLRHSSHVGIKSHQNNQQHQSIIGASENSEDGSGDVYNVPVPFQSDIYSLPVDSLISGNASKNASGKNGISQQHNSNQRLKLDTESSIKAPPPKKNNLNRRKSQDYSDQGIIIQSSQLKNPQIQQQPQPEERNTCRPPQRWSSLAVQPTSASVITKEEIASALSSASSSAFASVTSSKKPHIISNVVESSLQPPPPYTQPPPPITSKPFHKNGTTKENGSVSTESSQNNGNSNAGIAPPQSLNNTSDHVNNCKNGSLLNVSKKPRSRSVDPASGADYSNGSERQRSLKRPVGSTLSNAENVLNINFDHPLPPEPVLSGSNSDAHTNHPQHGSFKESPDRRNPLGLSFLNLFRRNKNGHGQKQTTHNQVKTDSNNGGASEEVSFPTSNNNLDNTGTINNNNKEDTSYYFRELPPPPPGHSDSSSEEQATPSPVECRDFAASIERVKDCGWYWGPLSSEAAEDLLRNEPDGSFIVRDSSDARYIFSLTFKLHGLVRHVRIEHDQGNFSFGPLTRFKAATIVDFVEKAVAHSRSGRYLFFLHRRPVLGPMQVQLLHPYSRFMHPRSLKHMCRFVILKYVRRDLIHTLPLPKPLQDYLNTPHYYFEPPDSNTKNNSSQNNLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ92</accession>
    <name>A0A1D2MZ92_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000392">
        <property type="protein sequence ID" value="ODM97975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ92"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ92"/>
    <dbReference type="OMA" id="EWYVNIS"/>
    <dbReference type="OrthoDB" id="196650at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031526">
        <property type="term" value="C:brush border membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF31">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="50"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="482" mass="51947" checksum="4743275766CB4411" modified="2016-11-30" version="1">MGYEQDKRLLSRGVRMVTTRSRSRVGDDVASKNNNNEKGSSPSSSKSKSILGVAVFALFIDLIGFTMILPLFPSILAHYKKTDTSGAYDVFVRFAAGVGEIVGAPAESDTVLMGGLLGSVFCFLQFLSAPILGAYSDVVGRKKVLLLCMGLIAASHLFWLFASTFALFILSRLISGLARANVSLTTTIICDDLPPEERPKGMAFIGIAFSFGFVIGPAIGAFFPWKSGSFQEAALACMLLSLTSLLIIWWKLEETLSASHRAPSFAAKLGDISHYVLPNHLFAFKSVSVGKELRGVGLAYFLYIFIYSGLEFTLTFLTETRFGFTRAEQGKMFACLGILMAFLQGTVTRRLKPWMEHSAAMLGMLFMIPAFIILSLAQDVGMFAIGLFCYSVGSAVCGPSLTSMLGGKVPRLNERGVAIGIFRSLGALARVFGPLVASSIFWRYGPETAYLVGAGSILLPLVVLKVVEGGVASPARKENKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N020</accession>
    <name>A0A1D2N020_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000338">
        <property type="protein sequence ID" value="ODM98636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N020"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="409" mass="45220" checksum="87D0E0E0A2B3B093" modified="2016-11-30" version="1" fragment="single">PEDEGDLESPKTSKSKVAKTTDFSCSEVMLSPCFDQFNSKQDCPQNESPHKKLRHVIEALPDGLDPDYVKALTINTLNTAENREEAKFIAEGKCDNNRESISPWSFCSGDSDAIESLRASFFPTDIHLEEAKKILGDRFYLLLQEVIKSPSFLDRLKLLIFHESNSALISTGRAPQNCQDAKDFLLCLQSIDPKVLMGSVSAVLSEIFLEHNLGQKADNVGATNNQEFAPTSECCTSSFINTTTPKAEIIIPSDLAEKVGNSSCSNVDATQGGNVSMPELGNVRDAISNTDDPDSDDNVTADSSLKLGLADKVWEEAYDLITLDKRDEKMRKMAQILFTEIFSDEEILECTVKGKKGTRVFDIDKVRGRGLVVRKARNKVTGGVRPLCLKQWSAFDGTGREKPENQRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N055</accession>
    <name>A0A1D2N055_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription termination factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08068</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000339">
        <property type="protein sequence ID" value="ODM98618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N055"/>
    <dbReference type="STRING" id="48709.A0A1D2N055"/>
    <dbReference type="OMA" id="ETRWCLT"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF50">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="680"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="301"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="606"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM98618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="785" mass="89376" checksum="28643936D9BE3732" modified="2016-11-30" version="1" fragment="single">RAGPESTDNAFWCVLKTMAADGKKKFLCPEDIVDDAFDHMAQNSAKPFSFTKRRDDTASTKKPIGATSRRYFDEEDEEEEDDSYPDSVNFDFGNDSDSGHGDSDIQVVQETPPSTSKGNPTALPQLKEKVHKVVNLDDSDDLEVLTDKLNKIPLGKQHPKQPPKIVFLEEAPPIERPKVMHMTLPMLDIKSSMETVVMLAETIETMPIPSENPENDDLPKGLVSLYDHQRYGLKWLSWREGVFPGGGILADEMGSSYYGDMEAKAEGPPEDDENWINTEEIQRLVPSRTTLVVCPVGCLLQWQDEIKSKGKGLRVHVFHGPTRTTSAALLAQNDVVLTTYDTVGSEVPKPDEIRRHSRSPLLRLYWHRIILDEAHNIRNPKTQRAVSICRLSARHRWAVTGTPVHNTPADFFSIVKFLRMVPFDEPKVWDFWIGLKAVKKAKEAQDRLHTIGKALILRRTKTEVEAMGGNVRAIPPKTVETIELDLNEAETRVYDHLMKFAQSMFKNFMENKDQREREMQGAAMTYTSALHKTLGSDVSDDIKVTHLLARICRLRQCAVLPHLIETMLEEEQVDEDDSFDELKDEHLVSKRNPIFARDYESSKLKRILDDLEEIRDRADAENKPMDKVVIVSSWTSLLNILYEHLRNRGFSSVFITGKEKMEERMDAMKRFNKYPDRPQIVLLSLAAGGVGINLVGGNYVFFVEPHWNPQMELQAQDRCHRFGQTKDVFIRRYVSKKTIEARVMELQAMKLDLADGVLKNTKKSNTGLSMHQMRLLFSGGNESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N059</accession>
    <name>A0A1D2N059_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Golgin-84</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08010</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000336">
        <property type="protein sequence ID" value="ODM98662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N059"/>
    <dbReference type="STRING" id="48709.A0A1D2N059"/>
    <dbReference type="OMA" id="QQEYMST"/>
    <dbReference type="OrthoDB" id="248903at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031985">
        <property type="term" value="C:Golgi cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000301">
        <property type="term" value="P:retrograde transport, vesicle recycling within Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019177">
        <property type="entry name" value="Golgin_subfamily_A_member_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13815:SF7">
        <property type="entry name" value="GOLGIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13815">
        <property type="entry name" value="GOLGIN-84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09787">
        <property type="entry name" value="Golgin_A5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="170"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="49"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="618" mass="69816" checksum="61BBC79999369FBA" modified="2016-11-30" version="1">MSWLAEFAGKAEDFLNKIDKNAAVVLHTPGTKENLTKPKKSEPFIEPVDSSNSRQDSVATVDSLSPVTGSSVNENLKSTNSGVSGSETRRSNNNKAQSQTKKIASAPKESKTVSSASNSTKPNSSVNRPVNQNGVDRKKVAKSSEEETRTNEDDLIAYLNSSESTGLNETVILKNEVENQSRELKLLTKNHRSLQKDHEDLKQKLQMYKDKLAREETTRHNSEAEEQDLKKLLEEREKEVSDLSCRHQQALQTLQQLEVSQENLQKLEQCLLDNSHLKSENETLVKRTEILASQAEAAENHVLSMKSTLSSMEKEFANYKEKAKSILSYKDELIASLKNDGSSPRSDTSSSSAEELMAEVTALKNERELLQADLSQTRTTVESLKDDTVRLEKEVSTLRSFTEDLGAQLHREKETVGSLQSENLQVCQQLTSLQFQLEREKNERKRCEEQVAKYKESSGNSSDSSGQNGYLSNSNHEKELSKLKTRVNALSQSLYEKQSLINDLSTDKQLFQIEVERLKNELRDCRIESNEFCHGSGLPQTVIASQPLYLSESPWDSRVSAKMKRIYTQIDAVFCQFGLALRKRPTLRLGMSFYVVILHLWVFFVLFSWMHHAVPEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N090</accession>
    <name>A0A1D2N090_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Bumetanide-sensitive sodium-(Potassium)-chloride cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000334">
        <property type="protein sequence ID" value="ODM98706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N090"/>
    <dbReference type="STRING" id="48709.A0A1D2N090"/>
    <dbReference type="OMA" id="CTHITKK"/>
    <dbReference type="OrthoDB" id="2020542at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008511">
        <property type="term" value="F:sodium:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055064">
        <property type="term" value="P:chloride ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055075">
        <property type="term" value="P:potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055078">
        <property type="term" value="P:sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000022">
        <property type="entry name" value="Bumetanide-sensitive na-k-cl cotransport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00930">
        <property type="entry name" value="2a30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF48">
        <property type="entry name" value="GH09711P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="601"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="655"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="684"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="304"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="9">
        <location>
            <begin position="804"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="943"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1061"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="943"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1206" mass="132758" checksum="2BD62A327C519974" modified="2016-11-30" version="1">MYILWARLPVATLNDDELHNCSSTTLQLIIIITRKLQWAPSPAVKIPWYNKGSFTFPNTPPASELGARSLSLITGSGTGIQHVPLDEIGSTTSSAPSSPNLNYSNTFPAVSLKPTGGNPSLSTTSITNPAYVPDMTDANNGDSRFRVNRISSSQLHAAPPITAGSHFAGAEMIPEDGTLEINNAVNKMGDGPAEIIPNQFMQPRRSSLAQGLGGGRKKSVTLPKEFDYLSELEDQHATVYGKNFAYYTREALPRMDNYKNLASVAHASRPTLDELRSEAMYAKKIDAPEEEVVSQAVKFGWIEGVLVRCLLNIWGVMLFLRLSWVVAQAGIGLAIVIICLSATVTTLTALSMSAISTNGLVRGGGIYFMISRTLGPEFGGAVGAIFSFANATAVAMHTVGFAESLNDLLKVLQVRIIDNAQNDIRVVGTIALIVMQAIIIIGTEWESKAQVVLLIILLVAILDFLIGAFIGPLDSDEFTRGYVGFNATVFATNFIPNFRENDGMKHGFFTIFAIFFPAATGITAGANISGDLKDPSAAIPKGTLLAILTTTGCHWPIMDDLNATDDAAASWEFAANCSAGIGEKCVWGSHNSFQIMELMSIFGPIIYAGCFAATLSSALACLVSAPKIFQALCNDNLYPGIGIFGKGFRKNNDPFFAYMVAFIIALAFILIAELNAIAPLISNFYMAAYAMVNFCTFHAALVKPLGWRPEFKYYSIYSSFIGFVLCLAIMFLMSWVTALITIGILACLFFGLVYIKPDVNWGSSAQAQNYKTALTTVQSLNSTPEHIKNYRPQLLVLSGRPSSRPTLLDLGYLMTKNLSILICGHIIQERQSFKVREYLVKKGNNWLIHHKVKGFYSLVDDVDFEEGARCLMQASGIGKLKPNIVLMGYKSDWTTCDLEDLKAYFRVIHDVLDNHLGLCIARVREGFDYSNVVEEDSEETVENLTRSDSSMSFSTIDPTPPGTPRIGETNDSFTMVPEGSGDDKKKSKKVKKEPGAEFRGVGGASLPKSVINNLTQFRTKQRKSTIDIWWLYDDGGLTMLLPYIIHSRNNFAGCKIRVFALANKQQDLEVEQSALASLLAKFRIEYSDLIVITDVMAKAKESTREFFEGLIKEYKKTNDSIEDEEMKIDPLEMKAMKEKTNRHLRLRELLLDHSRMANLIVMTLPIPRRNGMSAPLYMAWLECLTKDMPPFILIRGNQESVLTYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Z6</accession>
    <name>A0A1D2N0Z6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative RNA-binding protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_07771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM MRD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000312">
        <property type="protein sequence ID" value="ODM98908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0Z6"/>
    <dbReference type="STRING" id="48709.A0A1D2N0Z6"/>
    <dbReference type="OMA" id="GPITEIH"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000277">
        <property type="entry name" value="RNA binding motif protein 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="308"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="479"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="613"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="696"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="148"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="791"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="803"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM98908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="834" mass="93740" checksum="6522E3EACBFF6136" modified="2016-11-30" version="1">MTDKLKQLFGEKGEVTDVQLKYSAEGEISTLCVHMGTRTGSTTVFDKTFVGASRIAVELCHSLGEKPKPMSKVVRERQKAEKELLKKTKSADEEDEAKPPKKKRKEDEILEKCEQDPDFLEFLQAHKKTAATWGNDTLVDELMKLKEKKEKKKEGKRETEVEGLDEDAEEVEMQGKKKKLKTTDSTVKKGSRKRRKKKSKLEAEFFTLKLRDVPKKARKKDIKAFFAPLKLKSIRFPVGLRGIVFVGFGTETDQIKGLQKNKSFLMGNQVKIRAHNPLAPQANAAPKGKFEQLKEELDKVAEPIGESGRIFLRNLSYTTNEDEVTKLFGEFGPITEIHLPLDKITRKLKGFGFVSFMMPEHADNAFRALDGTIFEGRMLHLLPANPRMSLLRKRHKPAPHSKLKRSTIAKVISEKYGISREEMLLDKTDEQDSRLASVGVRMALAETEIVADTKKFLEENGVCLEAFDSNDKKAERSKTVILAKNLPANTSANDLKQLFLKHGVLNRIILPPSGVTGIVEFAEPAEARAAFRKLAYTKFFNLPLYLEWAPIGVFALPADAKQVLQLKADAKMLTVAEEAKKITPVEPVAKIMTQVEEFEPVDENAVPELDTTLFHFIQCGPVYAATVARKKDPSNPDVLLSMGYGFVQYYRSKDASKALTTLNGTMLENHILELKPSTRTLVKESADSTKKKAMGSKLLVRNVPFQATQEEITDLFKTFGKLKAVRLPKKMTGGGEHRGFGFIDFYTESDAKKAFDTLSKSTHLYGRRLVIEWASQDETIEDLRAKTARLASHSKDGVEQQESEGGSTKQKLSRYFQTHTMASKADQDEEEDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2G8</accession>
    <name>A0A1D2N2G8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CSC1-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07193</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000277">
        <property type="protein sequence ID" value="ODM99487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2G8"/>
    <dbReference type="STRING" id="48709.A0A1D2N2G8"/>
    <dbReference type="OMA" id="CSCKKEN"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="546"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="643"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="699"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="740"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="9">
        <location>
            <begin position="136"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="10">
        <location>
            <begin position="255"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="8">
        <location>
            <begin position="449"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM99487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="774" mass="88531" checksum="763072E7D24D917C" modified="2016-11-30" version="1">MTDFLTEGWEPEDTKKCNIYANYRKSGKFFGTDINGYEGIPQNLVLNVAGWIIMMLVFSVLRKKAWNYGRIALIQKNEMKWTDMFYGNNDVDADGVSSMKNGPTKVAVSDSRRATVTAKDSQPTTNGRIPKLKEILDTGLFSWIKIVFTLTDQQYLEKCGPDCVQYLSFQRHLIFLSTIITITALIVVLPINLQNKIGKDGPMEFSDTTIINLDKSRKFLWVHVILAVTFLFLSIAVMRHFSRALKFVEDDPAVSRTVMIIGIAKKYCDEDKLRRHFQEIYPDVSISEITFAYDISKLQYVEFLKLSSSSARVYWEEFLAEKHYRPTMRPYTCGAICCCCEPCGCKSTDAIEYYAADERKYTREVELERQRALTRALGIAFVTFKTLDMAERVVGDYRFTAKLLQQTPESKYTRKIKSKQWIVKFAPLPDDLYWENLTLGFKAWYFKIFLVNITLAIVIVIFTTPVYLLNSLSIPFANISSNNTTTGFGQTLRDQSPTLAGILVDTFPTILLWIGAVTLPSLVSVSDRIVGFWTKTAENRSKMIKIFSFLIFMVIILPSLGMTSLSAIYRRKGLRWPCIFSKDNGALFVNYVCTSTFLGSVSELMRIPELFVYCVKLCFARSEAEIAAIRKSVLWDFQIGSQYAWMMLNFAIFTVFSLIFPLVTPFGLVYLLMKHFVDRYNMYFAYAPTKVEKEVHGTAINFVIVCMFMLQINLLAYVLVHLEPDDKTQPNQPQMKGLKVFSVVGFCITAALFMGQVFFNMCANFSPILYKVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2H6</accession>
    <name>A0A1D2N2H6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000290">
        <property type="protein sequence ID" value="ODM99254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2H6"/>
    <dbReference type="STRING" id="48709.A0A1D2N2H6"/>
    <dbReference type="OrthoDB" id="413313at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004245">
        <property type="entry name" value="DUF229"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974:SF1">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="107" mass="11842" checksum="FD47A536B343BB45" modified="2016-11-30" version="1">MRLLIEATNHAVKSINQILSKYPQCPALSLASITGAKAVKGLAEEKLEQYQILFGTKPNNASFEATMSRGNTNEWSVSGTIDRTNLYGNQSYCVDDREAKLYCYCAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2Z8</accession>
    <name>A0A1D2N2Z8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000269">
        <property type="protein sequence ID" value="ODM99601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2Z8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="27152" checksum="6A22E31430FF6948" modified="2016-11-30" version="1">MAAIEFEEMRESEKLRKKLSEMKHRLCLFEFGIGSIASLVQDADEIRKISTRSDRKTAASDNQKRVIEGIVKILEEVEKSLSAAEAAQGIEQEAFRQDQLPTAAGVPCLVEVNPNVVTTTVSPKARIFIDETETGGNSLTRSICNIQVVENSAIFSAGGNNAASSASHYADPALAALSTLAAVATNQMEARSVKNGMGNTDTNLSQRSREVGLEKHVNNSGNTNVPFKKRKLVDRNVKSFTFKRPRDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N342</accession>
    <name>A0A1D2N342_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">39S ribosomal protein L48, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000262">
        <property type="protein sequence ID" value="ODM99696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N342"/>
    <dbReference type="STRING" id="48709.A0A1D2N342"/>
    <dbReference type="OMA" id="IRVSECW"/>
    <dbReference type="OrthoDB" id="5984298at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005761">
        <property type="term" value="C:mitochondrial ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027487">
        <property type="entry name" value="Ribosomal_mL48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13473:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13473">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="3">
        <location>
            <begin position="62"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="188" mass="21266" checksum="054C76B1030D7289" modified="2016-11-30" version="1">MQATSRIVRNFVSHSSKSISKLKIPEIKGASSNWRHFQSSATLNQGLGEPTDPEVPLYDALNVQVKGYDFAVLEKFARYVHHTAERVGLEVEDSWATPCKNLRVTKLKPESAVVDSEYLLNLFERNVQIVEVPATLLPVFINIVEASIPAGVTLRVHPHLPEHTENRYVPDLELMELKTQLQDIKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3G7</accession>
    <name>A0A1D2N3G7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000256">
        <property type="protein sequence ID" value="ODM99771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3G7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="32120" checksum="26CCEE56109C3A6A" modified="2016-11-30" version="1" fragment="single">MSKTQMFQRAKNTFLKMNLTPYLTDLMEARTYLEGIINQEEVKSINLHVPVLENFSRDDERLDLVHAIARMKEWSYMEDFDDIVKETSYGKKLDNASKIKLQIAASQTHDLKNASANKHLIPEQEISDDLALWTARQSFSIKDLFTADPTLFHTVASFSHLQNRSPKHNNSMAKANGSVSAESQRNSEVAFHHKRMVKRRKSANSMPSLPSLLRMLVKQRIANLRESGVSTTKTGQRLTDFRKKFLKADRFSDASEKELSPIVTLKQLRRSFQANSLTEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4D7</accession>
    <name>A0A1D2N4D7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lachesin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000231">
        <property type="protein sequence ID" value="ODN00138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4D7"/>
    <dbReference type="STRING" id="48709.A0A1D2N4D7"/>
    <dbReference type="OMA" id="HEPHTED"/>
    <dbReference type="OrthoDB" id="5969816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF36">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 9, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Immunoglobulin V-set" evidence="1">
        <location>
            <begin position="24"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12988" checksum="9A6B28E082BF68F3" modified="2016-11-30" version="1">MTHFDEIMLRYFIETLPIPFIVVEEEHLKVSWVRHRDIHLLTVGRYTYTTDQRFRAIHQPNTEDYTLMIKYPQHRDSGIYECQISTTPHLSHYVHLNVVGSLLAPTHEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5S3</accession>
    <name>A0A1D2N5S3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeobox protein orthopedia</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_06086</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paired homeobox family. Bicoid subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000197">
        <property type="protein sequence ID" value="ODN00607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5S3"/>
    <dbReference type="STRING" id="48709.A0A1D2N5S3"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000719">
        <property type="entry name" value="Homeobox protein orthopedia-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051895">
        <property type="entry name" value="OTP_Homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46770">
        <property type="entry name" value="HOMEOBOX PROTEIN ORTHOPEDIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46770:SF1">
        <property type="entry name" value="HOMEOBOX PROTEIN ORTHOPEDIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="82"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN00607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="14889" checksum="1A7EAB51E4A53693" modified="2016-11-30" version="1" fragment="single">MLNNIGAGGGTGAAGEQHRGYHHPGHGNTGNLCNIPDPRSLTTTTSISSVTGGLQLNNSGGLGTGTGTSTPVSSDSDKPVKQKRHRTRFTPAQLNELERCFAKTHYPDIFMREEIAMRIGLTESRVQVCPNQHIFQYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6B9</accession>
    <name>A0A1D2N6B9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chondroitin proteoglycan 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6B9"/>
    <dbReference type="STRING" id="48709.A0A1D2N6B9"/>
    <dbReference type="OMA" id="ADESECC"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905104" evidence="7">
        <location>
            <begin position="24"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="33"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="175"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="90"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN00772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="24481" checksum="496568D2605F4514" modified="2016-11-30" version="1">MNGYKTIFVVAAVVLCTLHVADSFSYERVNSDYNPCPGNFSGLLPNPEDCKSFYICDNGFPGLFPCPANLCFNPSVDACDHCAVVPGCEPGSSTRPPTNPTTSQAPTTTEPPNNSSEPSSEGTTTTQAPTTSSSVTTTTEAPTTTSEASTTTTQGTTPEPTTTTTQRTTTSNGEDLPCPSDPYIYQPYPGDCNMFYYCQDGVNTGVYKCGSGLWFNVQLQACVVPWGASCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6U6</accession>
    <name>A0A1D2N6U6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA polymerase delta small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000179">
        <property type="protein sequence ID" value="ODN00967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6U6"/>
    <dbReference type="STRING" id="48709.A0A1D2N6U6"/>
    <dbReference type="OrthoDB" id="3763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="5">
        <location>
            <begin position="203"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="4">
        <location>
            <begin position="393"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="644" mass="71394" checksum="9B869B6A7384162C" modified="2016-11-30" version="1">MAPQKNVATKEASSPSAVAPGGGQPQGNVINLMALAPQQLAQLKQQVEQELNFYQDAIIQLKEVQLKMQESNNCLKSLDPEKKEMLVPVTGSMFVKGELEEADKVWIDVGTGYYVEKTIEEAQDYFKRKVEFLTGQIEKVQSVGREKSTVRQGTMKLPESESLLSVPGSSDPGKKIDRESNADGVVVDEKFDARKLPRQFARQYAHSYSVRLWTMRPKLEELIKTEWPDVELKKIAELCEFSQGHGTTITTDPGNQKGAGSSKKGARTSDDHGQHIAFREDVTVAITGTIFKYQPEKPSILQELAEEKLMVPVVPKTKFISDQDTIQLEDESTRVQLVSTTGCGFTIGTLVNGVICALKGKPNVSGKFEVTDVLYPTPTPKPVLEQKLDYEMIFVSGLELDSDENSHLRIDMLFDYLEGLSGCPSEVEGTLKKRSKVFFVGDTFAKSKTGDDSKSESNRTEIALKLDGLLDQISQTMDVFILPGENDPSEPMLPQVPLHRCVFPQSSRRPTFRALPNPGRVEIPMSATKGSPKLDIILSSGQNVKDALRNSETTSALEMSQKLLRWGHLCPTAPDTIPLHPGVPEDVFVIENMPHIFAVGNQTAFDSMDWKNTKIFTIPKFSETGMAVLLNSDLEVMPLRFQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N718</accession>
    <name>A0A1D2N718_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">5'-deoxynucleotidase HDDC2</fullName>
            <ecNumber evidence="8">3.1.3.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">HD domain-containing protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_05639</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N718"/>
    <dbReference type="STRING" id="48709.A0A1D2N718"/>
    <dbReference type="OMA" id="TWRLCLM"/>
    <dbReference type="OrthoDB" id="10254258at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009159">
        <property type="term" value="P:deoxyribonucleoside monophosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000011">
        <property type="entry name" value="HD domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="14">
        <location>
            <begin position="25"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00015933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN01058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="22316" checksum="417B84F6DE1A5FA2" modified="2016-11-30" version="1">MRLFDFQHLDRTGWVRKGVTKPETVAGHMYRMAIMSAFLVDDASLDMNKCIRMSIVHDIGESIIGDITPNDGVDDAYKNKIETEAVEKLAGLVKSKSADEIRQLFQHDNRILHFSCRQEYEEGKTKEAKLVKDLDRFDMVLQAYEYEQMEGKPEFLQEFFDSTKEKLADSHPKVKGMLLELYKARENNVAFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7A3</accession>
    <name>A0A1D2N7A3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF243 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05559</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000170">
        <property type="protein sequence ID" value="ODN01121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7A3"/>
    <dbReference type="STRING" id="48709.A0A1D2N7A3"/>
    <dbReference type="OMA" id="EHYPQPA"/>
    <dbReference type="OrthoDB" id="10668963at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040003">
        <property type="term" value="P:chitin-based cuticle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004145">
        <property type="entry name" value="DUF243"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31927:SF2">
        <property type="entry name" value="FI07246P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31927">
        <property type="entry name" value="FI07246P-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03103">
        <property type="entry name" value="DUF243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00690">
        <property type="entry name" value="DM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905150" description="DUF243 domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="DUF243" evidence="3">
        <location>
            <begin position="203"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="385" mass="40532" checksum="140D36EE1180E0BA" modified="2016-11-30" version="1">MRAFLILASLGVLVAAEAPTSYSHRSSSPDLNFQPVPSVAQIHIPPSASRRSSSVSPSSSSSSSSSSSSSSSHGVHTASATSQIARYAVPPPSLAASAPSDESASSNLHHQATSYSSPHAVYAAPSQSQQTTAYSSPSSQSTYSAPQQTAYTSSSYAGPQLQAYSYPQIQIQSQPQYAAPQIQSQTQQQQQYALPPQQYSSPANVQVNYGAPPQLPPGASYGPAPLITGAGPEHNIEYRVVYVKGPKAPKPDLILPPPPPKQKTIVYILIPRVEPPEPIIVPTHAPTQPSKPEVYFIRYKAAKKNNKQSSTSFVNTVNSVSSEYGAPFGSASGPKPVVVDAPSPNRKRSTESATTTAKTTTTTSSTTESATSPTAAFGERVRKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N810</accession>
    <name>A0A1D2N810_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Staphylococcal nuclease domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000156">
        <property type="protein sequence ID" value="ODN01371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N810"/>
    <dbReference type="STRING" id="48709.A0A1D2N810"/>
    <dbReference type="OMA" id="CNLAYIN"/>
    <dbReference type="OrthoDB" id="10023235at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031332">
        <property type="term" value="C:RNAi effector complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20433">
        <property type="entry name" value="Tudor_TDRD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000018">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000018">
        <property type="entry name" value="Serine/threonine-protein kinase 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000001">
        <property type="entry name" value="Staphylococcal nuclease domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047386">
        <property type="entry name" value="Tudor_TDRD11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="8">
        <location>
            <begin position="15"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="8">
        <location>
            <begin position="210"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="8">
        <location>
            <begin position="389"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="7">
        <location>
            <begin position="594"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="28"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="729"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="772" mass="85800" checksum="328293E6B4D1C8F0" modified="2016-11-30" version="1" fragment="single">MSTANTPAAPAQPPQLFKGIVKQALSGDSIIIRGQPKGGPPPERQLNFSNITAPRLARRPGGPGGKADEGKDEPWAWESREFVRKKLVGKEVTFVVDYKVPASGREYGTVYLGKDTETGENVTEDIVREGLAAVRKEGKSDVTKLIELEEQAKSAGRGRWGAIPEVSINPFNHSNAINKHLLGFNCFHYLSFIHIQDIICTASLQAANDKEFVGTVTECVNADALVVRLADGSLKKIFLASIRPPRPSEQGEKGEKEEKVKPKEKPVRPLYEIPFMYEARAYLRKKLIGRKVQVSVDYIQPASQTFPEKICSTVKHEGVNIAEALVSKGYATVARYRQDDDQRASDCRGKGSKGSQGFAWKGHSGAHVVDLSGDAAKSKLFLPYLQRAGKISAVVEYVASGSRLRLYVPRETRLINFSLAGISCPRAGRASGPSGPPVEGEPFGKEALLFTKDLCYQREVEIEVTSIHISGSYFGFLFIDNKNLSVTLVEEGLATVHFSAERTQYNRPLQTAEGNAKGRRAKVWQNYEDTKDEIKPEDDKTERKVDQKPVVVTEITPELHVFVQFTDDGDKLEALMNDLRRELNEKPPMTGAYTPKKGDLCAARYSGDGQWYRARVEKTLPDGEVAVVFIDYGNRENVKGRKCATLPAMPAFPRPPFAKEYALACVNLPTDKFVRADALYAVRHDTADGVFLLNIEYKTGGLDYITLADKTTKEDIAQNLVKEGFLLVDNRKERRLQKLVKDYQAAEKEAKTQQLNIWQYFNITEDDTLDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA72</accession>
    <name>A0A1D2NA72_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Unc-112-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04534</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the kindlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000123">
        <property type="protein sequence ID" value="ODN02153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA72"/>
    <dbReference type="STRING" id="48709.A0A1D2NA72"/>
    <dbReference type="OMA" id="PEHGIHY"/>
    <dbReference type="OrthoDB" id="10057618at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030055">
        <property type="term" value="C:cell-substrate junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13205">
        <property type="entry name" value="FERM_C_fermitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17096">
        <property type="entry name" value="FERM_F1_kindlins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000037">
        <property type="entry name" value="Fermitin family homolog 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037843">
        <property type="entry name" value="Kindlin/fermitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040790">
        <property type="entry name" value="Kindlin_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16160">
        <property type="entry name" value="FERMITIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16160:SF13">
        <property type="entry name" value="FERMITIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18124">
        <property type="entry name" value="Kindlin_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 4.1" evidence="5">
        <location>
            <begin position="42"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="378"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="679" mass="76814" checksum="D9AB9F06422246E5" modified="2016-11-30" version="1">MGISADWSDHALWWPDRNMWLTRTRFTLDQYGVQADALLYFTPVHKLLRVELPDRRVLDCKVDFSIKTFNAVVQLCKELGVRHPEELSFCRPLLPEHLKQNYQQVRNRKISHAEEMSRGRSPLPPDTNTFIATASSNGSMYSRHNNSTVSSSSSGSSGGGYGERFLCAPVRSSSNKNTPISSPMSSGGSGGGGWNSNGASPYNTMNNKMNGSYSPQPFHLNGGNDFDLDVLAQSGPPVPPEIRNKMLRPKNLVERARMNVAWLDSSLSIMEQGVREFDLLCLRFKFYSFYDLNPKYDAVRINQLYEQARWQLLNEEIDCTEEEMLMFSALQLQVNLQANVPQPDVNNVAEDDIDAALNDLQITLEGSSLSSRNHQHVPELSDVLRVMKPKKFTLKSFKKYHATCRDLSVNFQKSPGDIDSSFSISLRGCEVTPDVNLSQGKFGIKLEVPGPEGMTEYWIRCDSEDQYARWMAACKLGSKGKTLADSSYDTEVRTIQTFLAMQKRAPAPAINPSSFEINPQDYVAARFLKKMKGKLTQRILEAHANVKDCNLIEAKMNYIKAWQSLPDFGISLFVVKFSGQKKDELLGVAFNRIMRMESNTGDHMKTWRYNTMKAWNVNWEVKLMMIQLDDENISFSCLSADCKVVHEFIGGYIFLSLRSKDASQTLNEEQFHKLTGGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAA8</accession>
    <name>A0A1D2NAA8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000121">
        <property type="protein sequence ID" value="ODN02190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAA8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="395" mass="41777" checksum="4143E01B1DBBC25F" modified="2016-11-30" version="1">MTCGFVEFCNEDFPTPPRLPPPPPILSYYFEDNKLNSTFYCDFCSNLEASLDPLHTLGNAAGGKAGGLLSPSQNITLILLIVAMVSAALGSVVTMVWRKWFRCRDGGILSKAFGASHSSHSADISSSPEGRRRSRTASLGSGSALQNLQKRLSSSSFISRRSIYPHHAGNIISQHGSHLRTGGQSMSNNTYCECPSSMMMMVCPDSTGGGNNSTINNPASPPVSTTTSAVSLSPCLAINPTAPTASTLSINTSGNVYAELDPVSTPAVLVPHGVAPPTPLMMPMIINPNNNGGGIIASPTLNQYVVNHRRRQPAPLPPIPTSEASIVANNALNISNCANSTSNTSSSIPPNILAGINHGSIGVIPSLNGFENNQMEMNDLNDIYYSDLDCKQIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAI6</accession>
    <name>A0A1D2NAI6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAI6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="62"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="14287" checksum="EF8D063E90956ECE" modified="2016-11-30" version="1">MLDTRQKLRETVEANKGLSTENSKLVVKINEFEATVGELNGRLNSYSGKITTLEQNLKLKDIEKETQKKDILQLRAENSELQANLEKEKKEKEECQKKLEKIRSEVQNLEELFDDDMTENGTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB32</accession>
    <name>A0A1D2NB32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB32"/>
    <dbReference type="OMA" id="VINCTHF"/>
    <dbReference type="OrthoDB" id="7771743at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="410" mass="46056" checksum="C58C594B3F1DB517" modified="2016-11-30" version="1">MPCKTFLRHDQTSSQRSSSSSKEVTIYAPTWVQEGVKIVGNKLKSIEFQVHEKPSLKRGRNADTVTPKLLESFIISEDLNNKSLVLLHKIARNEPRNTNGIINLTYYSPDIKDTSLIYFMKDLARQSIVVGKDTTTFLGGYKSPKVKQAGEPVYLCDLAALQFQKPYNSGRLVLLQQNDPYKGPFDDVIFEHVVGEKKKSFAEVNKAKDDEGMKKRYLKHDGYGGKAGPCYLDGVAYRKFVKTDVLLCGLALADLAAEKGDQLNFKFLKYGTGYFAGKFVKELNSLILFGVVDGLEELFSRKDNKNVLDVIKALEFPFYECDPDNRKRLDELKKRYNVEYRFSRDDALKQTMKGSGLITATTNCADSNVACGNAMGFKSTDGAIAENLLSKGNIFCPNMNNLMSYKYLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB90</accession>
    <name>A0A1D2NB90_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox protein ceh-19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000108">
        <property type="protein sequence ID" value="ODN02520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB90"/>
    <dbReference type="STRING" id="48709.A0A1D2NB90"/>
    <dbReference type="OMA" id="FAPESPN"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050848">
        <property type="entry name" value="Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333">
        <property type="entry name" value="HOMEO BOX HB9 LIKE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333:SF9">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="164" mass="18313" checksum="DB8566ED511BC116" modified="2016-11-30" version="1">MIEESQTLPPKPTGRRARKPGVDRKPRQAYSAKQLERLESEFKIDKYLSVSKRLELSKALNLTEVQIKTWFQNRRTKWKKQVTARFKLAQRQGLGSHFYSSFSSAFAAAQLSPFYAPPIFSHIPTPQHSSGQDQNGSGGTSGRSNVVTQLPSSSPIVASHPLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBD9</accession>
    <name>A0A1D2NBD9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_04110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBD9"/>
    <dbReference type="STRING" id="48709.A0A1D2NBD9"/>
    <dbReference type="OMA" id="ILEIGMT"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN02563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="511" mass="58100" checksum="01BEAC644F8842F0" modified="2016-11-30" version="1">MVYANSHVIDMEKLRRHEQTVEDLRDTFLTGKTRDVEFRLKQLKNLLRLYSENWDRIADALCQDLRKPLGEAKIMEHAFLIGDVKYAIKNLKKWAKSTAIPTCLANVSDNAWYRYEPFGTVLIIGPWNYPFMLAFMPLCAAIAAGNCAVIKPSELSPNSAAVIADLVPKYLDRSCYKVVTGGPEAAQELLEEKWDFIFYTGSTTIGKVIYSAAAKSLTPVCLELGGKSPVYVDNTADMKKTAQRILWAKCANLGQTCIAPDYIICTKEVEDNFIQECRQILRDYYGTNLKASKDLARIVNKRHFYRILKYLAETKGTIALGGENDERELWIEPTILVGVDPTEPIMSEEIFGPILPICRVGSADEAINFINRRPRPLALYVFTNDSNTTKKFVKFTHSGSICVNDCLYQSSLHQLPFGGVGDSGMGQYHGQFGFQTFSRPRAVMERSFSNFENMTAYKLRHPPYLNSHIKLNSWVVERFDMLFVNPWPYIPYLVMFILGLLVMFSLQRTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBE9</accession>
    <name>A0A1D2NBE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lymphocyte antigen 75</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000105">
        <property type="protein sequence ID" value="ODN02578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBE9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905315" evidence="1">
        <location>
            <begin position="19"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="61"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="433" mass="49513" checksum="8A0E09662B57AF1F" modified="2016-11-30" version="1">MLFVQIFSLIFLYQFGGAVRPAYEDDPELCPFTNRLTINGLPTEVTDRTPGIKYFRRTNDSRERLPFDQATSICKTYNLEAAEILDQDDYDEVINLVKETGWSFWIAVRGRYNPEFGNYNFDFKLADGQSRLGFQDFGPKAYDSEMTSLFSTFREGCVAVVPNDGHSKGVSWVKAPCVELNDILCQYKKSCYKRVEYMSDPTRPASPLEPLSLSEDAEPGYMISKIQATWPFAKQVCEDAMMDLIWLDGKAEKAEFHKRLDKFMAGKAQYEGKTFWTAGRYSQKQDSDLYDRLYLWQRNNVSYIHGFNAAEKYGRSDDDAFPVQWGMDQEAIHMGRSEPYDEGLSGTEKCVDALFTDDAAKFYTSKCNKAMRYFICKSSVNVQRLLTPDGMPKSSFVDYCVGDQYHKKSEKDCNGEVIFSGPTKPQCTCYNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCH8</accession>
    <name>A0A1D2NCH8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000091">
        <property type="protein sequence ID" value="ODN02950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCH8"/>
    <dbReference type="STRING" id="48709.A0A1D2NCH8"/>
    <dbReference type="OMA" id="DPTNPMY"/>
    <dbReference type="OrthoDB" id="5797993at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37962">
        <property type="entry name" value="MALE STERILE (3) 76CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37962:SF2">
        <property type="entry name" value="MALE STERILE (3) 76CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="27889" checksum="1D838AC9E4530C6A" modified="2016-11-30" version="1">MARYVEYTPDVFSQTDRGVNVWWFPTTFSQSQLGDRVIGSNACTLIAVLLGGRVTEFNIVIWGYQDQPLSRMLVTSLAEAIIEGNEIHESLMAEGTVNSMDLTVPEALRAVQFKYSNLVEWGDRTAFVNEPLAETLIENLLPVIIDFEHAPPERKRPNTDLFAILVCDGRSVLFVYQPSTAKVTVIDSHAHSSCMSGAVIAQARFGDLEQLCNWFFAMLTQSFERGARVQPYELAFLYIRDDAINPSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND65</accession>
    <name>A0A1D2ND65_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_03475</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND65"/>
    <dbReference type="STRING" id="48709.A0A1D2ND65"/>
    <dbReference type="OMA" id="NTSMRIN"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000092">
        <property type="entry name" value="Serine/threonine-protein kinase 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046409">
        <property type="entry name" value="PDC10_dimerisation_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="8"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="255"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="322"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="360"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODN03198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="601" mass="67111" checksum="82EE68A05B54C151" modified="2016-11-30" version="1" fragment="single">KVDPELIFTKQERIGRGSFGEVFKGIDRRTQEVVAIKIIDLEEAEDEIEDIQQEIMVLSQCDSPYVTKYYGSYLKGTKLWIIMEYLGGGSALDLMKAGPFEEIHISIILREVLKGLDYLHSERKLHRDIKAANVLLSENGDVKLADFGVAGQLTNTTSKRNTFVGNDRAGEGEPPKFDDASDESVVFNTQEPSPTLSTSRYSKLFKRFVDACLNKNPENRPTAKELLKFPFIRRAKKNAYLVDLIDRFRKWKLERSDESETESDSDNEDTLRRGESDVDDPWIMTVKGPSASNSSSSLDSLSSTSSTSSFIPGILSGVSSQSNSLTLSVEDDDQVDHHQTPDDDDDDSDDNMDSRRSHSSHSMGSNHMDSSQSIQHHGQHSSSSSSASEEYQNHNNAFTKFQKLDQQLQQQQQQQQQQQQQQQKNYQRNRSVSPPSQSQGPAPVFKNQIHVQNSPILGQSQANHHRDRSDSGADNNNYGQPRPRESPERGKLGGQQRDHGGMNKPSTSHHKGSNHVNSSSSSNGVVASVLTPILIEMRRKPGTNGTQKAEVLDDLRRAFETAEAASPGFSEIFLRETLSRLLPSVSDARIKATVSRMSREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND75</accession>
    <name>A0A1D2ND75_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03486</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND75"/>
    <dbReference type="STRING" id="48709.A0A1D2ND75"/>
    <dbReference type="OMA" id="KCYCVSC"/>
    <dbReference type="OrthoDB" id="10262653at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN03208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="113" mass="13108" checksum="834BCA2A34F20A4F" modified="2016-11-30" version="1">MTSKRRNNGRSKHGRGHVKPVRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVYTNYILPKLYAKLHYCVSCAIHSKVVRNRSKKDRRIRTPPPRFPRPDQRAQQNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDX3</accession>
    <name>A0A1D2NDX3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_03219</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000072">
        <property type="protein sequence ID" value="ODN03468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDX3"/>
    <dbReference type="STRING" id="48709.A0A1D2NDX3"/>
    <dbReference type="OMA" id="NCANEQM"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="195"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="370"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="560"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="611"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="614"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN03468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="640" mass="70583" checksum="F66FC7E0340B7921" modified="2016-11-30" version="1">MTTKEVNGHASSAADGEKQTKMEGDTREEKASSQQLHHDKISTATTISVSGVNVLPNNNTDVEAFGERDQDKALRRKWEYFPGKNRFYCNGRVMTAPSIRFCVLSFALILLTFTLFLIFDAPFLTERVTVAVPIVGSILFISVVVNMFKTSFSDPGIIPRASQQEVDHLEKLYYSTNFRPPPRTKDIVVNGQVIKSKYCFTCKMFRPPRASHCGVCDNCVDRFDHHCPFLGNCIGKRNYRSFYTFIVSLSFLAVFVLSASIAHLVMLSKERGNFLDALRDSPSSAVVIVISFFGMWTVIGLTGFHTYLIAVEQTTNEDIKGLFGRANAKNPFSHGNFCQNCCFVLCGPSQPSLLDPRGFATSDFVASLPRKTDPNGMLSPGKTSQLTPAKSSSNCANEQMGQQGLGGSFGGSNKIYREQPPLAVQPVQHQPLQFSSPPPESTSAQLQQQHSKVPLPGLPIIPPEEKVLLKGQTRNGRTVVSDYRQTVPESIQEMKLPHGQPLTSPSAASTVSLSTVSTSNISNDYDTVSPVGVSVTTSNMSNNHLKNLNNASSSKRVFLTSTSSEQRKLKDTESDPYDSERLVDPSDFDDDLDMPSLSNVNDIEMRKNIKTFRGSNSQSQTTSNGNVAFTDYRARRHRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFM1</accession>
    <name>A0A1D2NFM1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit RPB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02776</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000060">
        <property type="protein sequence ID" value="ODN03885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFM1"/>
    <dbReference type="STRING" id="48709.A0A1D2NFM1"/>
    <dbReference type="OMA" id="FYFEVES"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07031">
        <property type="entry name" value="RNAP_II_RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="31446" checksum="76248C92045BFB74" modified="2016-11-30" version="1">MPYANQPSIHIRELTQENVKFHVEDTDLSVANSVRRVMIAETPTMAIDWVQFEANSTVLSDEFIAHRIGMIPLTSDDVVDGMKYTRECECEDFCRQCSVEFDLHVQCKDSETFHVTSANLRSSDPRVVPVTSKGKDDDAPEYEQQEDILIIKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNSLRHTLFPKPEEWPKSEYSELVEEDQHEAPYSYEAKPNKFYFNVEASGALKPENIVLMGIAGLKKKLSDLLTQLTTEMHGEMLPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFM3</accession>
    <name>A0A1D2NFM3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein Wnt</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_02667</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Ligand for members of the frizzled family of seven transmembrane receptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
            <location evidence="1 10">Extracellular space</location>
            <location evidence="1 10">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Wnt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFM3"/>
    <dbReference type="STRING" id="48709.A0A1D2NFM3"/>
    <dbReference type="OrthoDB" id="5945655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005109">
        <property type="term" value="F:frizzled binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060560">
        <property type="term" value="P:developmental growth involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007517">
        <property type="term" value="P:muscle organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2460.20:FF:000001">
        <property type="entry name" value="Wnt homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005817">
        <property type="entry name" value="Wnt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043158">
        <property type="entry name" value="Wnt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018161">
        <property type="entry name" value="Wnt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027:SF77">
        <property type="entry name" value="PROTEIN WNT-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027">
        <property type="entry name" value="WNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00110">
        <property type="entry name" value="wnt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01349">
        <property type="entry name" value="WNTPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00097">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00246">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="56"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN04037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="423" mass="46742" checksum="671719BE01001935" modified="2016-11-30" version="1" fragment="single">SIYEFSSSFCVQDHMRPVILGAKLGLSECQWQFRHHHWNCSSSAVIQSRVLRENKPAPSFGNSGNGNYAGEMPPSSSSSHSESYRVGSEDSTPIFQQGTLSKKQKQQQSKMTSVLTQTSGKRLLRPAAVSIAASTSSSLPSSHPRSSNHYIITKEKTNWNTVLTRGDHCNHDPYLYITPTIQSLFSDFNGSKEVAFAHAIWSAAVTDAVARACRDGSLTSCGCGKTPRPPDLRAEFAQSFVDIREQESVPLDKKAKARSLVNLHNNEAGRRAVLKKTKIACKCHGVSGSCALVTCWHQIPSFREIGDHLKDQYVSATQVKLNKRGRLQVRRSGVRVPSVFDLVFTEQSPNYCVQNETLGIFGTTGRVCNRTSTAAGSCKSLCCNRGFKTNVVKSHNRCNCKFIWCCQVVCEECRSVQKFDVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFR2</accession>
    <name>A0A1D2NFR2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Antileukoproteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFR2"/>
    <dbReference type="OrthoDB" id="9985779at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019731">
        <property type="term" value="P:antibacterial humoral response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050514">
        <property type="entry name" value="WAP_four-disulfide_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19441:SF95">
        <property type="entry name" value="PERLWAPIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19441">
        <property type="entry name" value="WHEY ACDIC PROTEIN WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905512" evidence="1">
        <location>
            <begin position="18"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="16"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="80"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="15666" checksum="C99A2A2C97B5F346" modified="2016-11-30" version="1">MKAILVVAAVLLCTVSAQKPPRGCPSNKGTFGICTFDPNVNCLQDSQCQGGQLCCPDGCNRMCKDPEPEIVNESSPAPPPSLEVMHCPPVTGGSFGICTFDPNVNCLGDDQCQNGQMCCADGCNKVCKEPVRFQPLKPQPKPALVPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFT9</accession>
    <name>A0A1D2NFT9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spaetzle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFT9"/>
    <dbReference type="STRING" id="48709.A0A1D2NFT9"/>
    <dbReference type="OrthoDB" id="6594799at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005121">
        <property type="term" value="F:Toll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0021556">
        <property type="term" value="P:central nervous system formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.90.10:FF:000018">
        <property type="entry name" value="Spatzle 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032104">
        <property type="entry name" value="Spaetzle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052444">
        <property type="entry name" value="Spz/Toll_ligand-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199:SF5">
        <property type="entry name" value="PROTEIN SPAETZLE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16077">
        <property type="entry name" value="Spaetzle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Spaetzle" evidence="6">
        <location>
            <begin position="492"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN03955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="663" mass="73700" checksum="CEB687D7FCF37864" modified="2016-11-30" version="1">MTVGVDDCGAPDTMEGSRSDGGCSKCGGGGRNGSDISDSDPFILRTRRGTKYRRRDEEVVDLDVKDGYSLVIPSSWTLLLASLVIIICSISAVSAIDLTPHGGFYHQRDEFSSSQSEYGGGGDDMIMTCSRPTKSSRAAKYLAIKQLDIPCDMVDKKAAWCNLPGDKYPWHAVRRFVFENQGLMRRMYGEVRQLSLLRMEFEDDLDDELEEERRMPPRAPPLTEDHRRNSILTEILDESLPRVLSQSPPGDQLLLRDHNNLMNGRGSTPRSFPAGAVENYKQRSSEELLRIMNNETTEVTIPSEQVTTDSVVLVASELLNGTTTTTVVDLGETGAPVTAGSVRSGVAEEVVVVTEEATQSTASGITEMENGTDEEQALLAAVGGGVVTTTEEITMSSLNENGDDEVVNQEPGSEQVGLNLNQQLNDGGMEIGGMGSDESHDFLNLDKNHILYFDDVGKNRRPVGGGSDQYAQPPRQEDMQQQAAQGKLKAVNACPVKEEVVAPYWANNTRGEILALLNLYPFEQYIHWERCNHENKQMFCRQGCRCEQQYRLHRLLAFDPTNECRGIFSDWFRFPSCCVCRCYLNEYELMMLNAAGQDNPPPSSAGSPKSRTSDRIRSPRKILLEQLVDGPDVHGVDDIHFFYKQGFNHEHNHGAQPRRKRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHW3</accession>
    <name>A0A1D2NHW3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Whirlin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHW3"/>
    <dbReference type="STRING" id="48709.A0A1D2NHW3"/>
    <dbReference type="OMA" id="CYVDMTK"/>
    <dbReference type="OrthoDB" id="10029564at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002142">
        <property type="term" value="C:stereocilia ankle link complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032426">
        <property type="term" value="C:stereocilium tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051844">
        <property type="entry name" value="USH2_Complex_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23116">
        <property type="entry name" value="PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23116:SF29">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="80" mass="9221" checksum="3DC77C6321AE7BC5" modified="2016-11-30" version="1">MPMNNKRITFLQPDGSAFHSNLRAGQVLLTVDGKKLDGLTHEEIARLILDCYVDMTKSQIEFLVVEAKQNYYYFNTHQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI40</accession>
    <name>A0A1D2NI40_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Signal recognition particle 9 kDa protein</fullName>
            <shortName evidence="9">SRP9</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02031</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SRP9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000038">
        <property type="protein sequence ID" value="ODN04646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI40"/>
    <dbReference type="STRING" id="48709.A0A1D2NI40"/>
    <dbReference type="OMA" id="DPMKVRF"/>
    <dbReference type="OrthoDB" id="360923at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008832">
        <property type="entry name" value="SRP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039914">
        <property type="entry name" value="SRP9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039432">
        <property type="entry name" value="SRP9_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834:SF12">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05486">
        <property type="entry name" value="SRP9-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017029">
        <property type="entry name" value="Signal_recog_particle_SRP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP9" evidence="10">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="9304" checksum="C20B21513E0C2668" modified="2016-11-30" version="1">MYLKTYDDWEKAAERLYLQNPDTARYSIIYQHNKGLFKVKMTDDATCVQYRSESMQEFKKMEKFVSNLLRHMASTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIW1</accession>
    <name>A0A1D2NIW1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIW1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="436" mass="49725" checksum="442603E6212AA460" modified="2016-11-30" version="1">MTGTSGPDIIAKSGMSDIYLKTIRVAPKAKTKSNKKIPFGSSLPRDLYSLWKIPNCQLPFCRPSPFKKTPDEIKVINTSPFAKPGESRSEELMRVGRAIISIPCRFRYTGSHGELRDRVLNTLQFESTLQDKAQAYIKAWEDFENHTKPFYSKADDACFLPKLSAALIDGCLKEGVDLGLRRVNSDSDLEPGIYRQRYGKEDVYEEEVIIVEKLTMDEVDRLRELPRRTLMRLFGSNANLNAELLEEKVLMLPIKPRKKSSSINRLKTLNEADETESALMERVERKLRPSYQSIIQPIKMPTDEEDIPEAFKKMVPKSKKEPEVPNILKYFMDRRKEGEKKEAEKQVQLHKKKVPLPDWPTLVNSVMEENVPSTLKKLFLTKEREGFATSKESISRSDLTKASMSKESVSRKSMSKISTSKESVSRASAQIKSVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ64</accession>
    <name>A0A1D2NJ64_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger HIT domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01425</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000027">
        <property type="protein sequence ID" value="ODN05252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ64"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ64"/>
    <dbReference type="OMA" id="CIPCGAR"/>
    <dbReference type="OrthoDB" id="74807at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21437">
        <property type="entry name" value="zf-HIT_ZNHIT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039723">
        <property type="entry name" value="Vps71/ZNHIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13093">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="6">
        <location>
            <begin position="114"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="17290" checksum="1E7A7F877660A859" modified="2016-11-30" version="1">MAQREQRITSAARILDAAARYRRKKKALEALEQDNFHDEPHADLVMSKKVPKFQESNEKGPTKKRKQRSSEYYKLKFRKAINTLIEEEQLENVEGPNYSTAAAPSSKLPPRSFCTVCGFPSTYNCIPCGGKYCSLKCLKTHQETRCLKWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJN1</accession>
    <name>A0A1D2NJN1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Leucine-rich repeat-containing protein 51</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJN1"/>
    <dbReference type="STRING" id="48709.A0A1D2NJN1"/>
    <dbReference type="OMA" id="CMINKIE"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46545">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46545:SF1">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="337" mass="38897" checksum="9856F1EEC128B685" modified="2016-11-30" version="1">MEAKMIANTVTVRPKIPSILIDATIKTIQAGMRVDEFSKSGDKNQGNERGRSVKKKVENKDDGRLKKRMQNRRDADDDDETTRTYRNFDERRGAFLIVGDQHRFVGKGDENKFIFPTAPPLDYSFCMINKIEEIVTESEQPQTKRNFRFPEKTPDERYKTSSLRLSYNVIDTIEGLINVLYKILDGGPFGLCWLDLSFNTISKIDEDTVSQLPNLKILYLHGNALTDMTEIPNLRCLKNLVALTLHGNPVEEEDGYRISVLFYLPWLKHLDFVAVTKSDMANSYEFGEKFEPYWVKRHDELEAIYQSRKKAGEITYTEKVMQGFDPDNDEDVEPQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJX1</accession>
    <name>A0A1D2NJX1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Copine-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJX1"/>
    <dbReference type="STRING" id="48709.A0A1D2NJX1"/>
    <dbReference type="OMA" id="MVHETEF"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04048">
        <property type="entry name" value="C2A_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04047">
        <property type="entry name" value="C2B_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000099">
        <property type="entry name" value="Copine 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037768">
        <property type="entry name" value="C2B_Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="306"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN05578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="566" mass="62885" checksum="F30C2F14514B24D0" modified="2016-11-30" version="1">MNDEFTPGTFVEPTSTVEISISCRNLLDMDVFSRSDPMCVVYHHPAGMSHWVELVRTEVIWDNLDPDFVTKVAIDYRFEIEQPLRFEVYDIDAPSANLENHDFLGYAECTLAQVVAAGYQGLSLPLLQNKSKYYPILPKNAKISKGSIILLAEELVQFKEEVTLKVQGYSMGRTKVYSCILAPKIFFVLSKINENGSYTVVYRSEASPGKTPVWRPATIPMRTLCNGDKDRTLQFHVFQVGLNGYHSSLGMVFTTVNKMSELVGSETVNLTGKNGLEKAATLKFAQVTIAPVFTFMEYISGGTQIHCCFAIDFTATSGSRPNPYEQAIQAVGEIIQDYDQTKKFPAYGFGARVPPSGEVRHNFPVTLTDNPFCNGIEGVMEAYRNCIRQIQLYGPTNFAPVIRDVANLARKNMEGNHYYVLVIITDGIITDMPQTKEVIVGAAHLPLSIIIVGVGRANFAAMDELDGDTVRLSYNGKFAPRDIVQFVPYRDSYTWMASVSPDAVQWYSGYESTGKVAKIRLAQEVLAEIPEQITSFMKSRSIVPVGRKTDQPTRARVTSGQGTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKZ1</accession>
    <name>A0A1D2NKZ1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">acid phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKZ1"/>
    <dbReference type="STRING" id="48709.A0A1D2NKZ1"/>
    <dbReference type="OMA" id="IFIANEC"/>
    <dbReference type="OrthoDB" id="5821688at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF211">
        <property type="entry name" value="PROSTATIC ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905701" description="acid phosphatase" evidence="9">
        <location>
            <begin position="27"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="49880" checksum="97755781A90E7AE0" modified="2016-11-30" version="1">MKTNFLARFRILVTLLLCLCVGFSTSQNQTSEVNHETLKLVQLIIRHGDRVPEYPYPNDPFSDPSTWPEGWAQITDEGKRQEYQLGQYLRTRYGNYLNSSYVPNQIYAVSSDTDRTIMSGMMALAGLYPTNNETNWNSTVNWQPVPLRTIFTDDDNLIRFKRKCPKFDELFDDFIHNSPMMKKINEDNKELYANLSANSGVNITTINEIDSFYATLFVEEFKGLDIPEWGRPLKTDEHFQYLYNLSFQAKTYTPELQRLRTGPLVKYLTDNVNERVHNASLKTKMFFLSGHDITLVDILNTFGVFDLHRPTYASVFILELHQDPNTEKFFVEFFLRNDTTREPYKLTMPGCEFQCPLESFQNYTKRIIPNNWAAECQLTVPAIIEESSVFTYTIIVVGVVALVVFLIGLGCMMLQKKRRIVQQQEYQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL37</accession>
    <name>A0A1D2NL37_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transforming acidic coiled-coil-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL37"/>
    <dbReference type="OMA" id="NILMSMT"/>
    <dbReference type="OrthoDB" id="10052054at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21010">
        <property type="entry name" value="AGAP001581-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21010:SF3">
        <property type="entry name" value="DAXX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="241" mass="28367" checksum="9112D0D2B187C9CE" modified="2016-11-30" version="1">MDPQLDDYSYRSNLVGKFTQSVRRIVQDVRDEGAPSGQTKEEAMRTQLRLRATRRRLEINYETAKQALVNLHNQYEKSKEVRNVFTRYALLKSMIKEVVRLETQYWTLLDVPKQEKAEPVGCYVLRACSALEKVQLKQIEKAAAENEDRLREEKERLEDMTSTQIEAENTQLINDLYRLLKRYTGLRNLIRELTGEYTSSKYYPIIIRYTLLKDMIKEVTHNPDYMEVRHEHTISSIVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLQ7</accession>
    <name>A0A1D2NLQ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Cadherin-23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_00583</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NLQ7"/>
    <dbReference type="OMA" id="DQGKNGT"/>
    <dbReference type="OrthoDB" id="6510378at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048589">
        <property type="term" value="P:developmental growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001736">
        <property type="term" value="P:establishment of planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000098">
        <property type="entry name" value="cadherin-23 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000168">
        <property type="entry name" value="Cadherin-related family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000020">
        <property type="entry name" value="Dachsous cadherin-related 1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000039">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000118">
        <property type="entry name" value="protocadherin Fat 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF422">
        <property type="entry name" value="CADHERIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1928"/>
            <end position="1952"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="225"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="317"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="428"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="535"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="650"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="761"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="886"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="1015"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="1136"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="1244"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="1376"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="1468"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="1576"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="17">
        <location>
            <begin position="1701"/>
            <end position="1824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="81"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="984"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="84"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="990"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN06167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2020" mass="223434" checksum="99E7547EB32F57BD" modified="2016-11-30" version="1">MRANGLPQKVFCNCCCSHTSSYSNNLSTTQPHISDKTSDSPVAPAKSNRRATSDNGKDADGREKNLRICCNKQRSYISKNKNASSSHYNDNCSSSQTDELSSPSSSSLQRLLSQSNSRSGAAAEKLRDEQMPKIYANNSDDAILPCSSNKCKSMRNSNHICSNYRQGTSFCRINFRLPLPLLPFLVLSCMIAIFPQMTVANVLPQFVLKDGQSEIVLRLKEGPATPVGSLIYKLKGVDGDSDPLTFGLRGQVANELLRIENLGKDEANLYLRKELDREVQDEYMIILTLNDGKLAEPVQQSLLLLVEDQNDNTPVFQPYQSTIKVPENSQVPQVLAKLTATDSDEGPYGQVIYKLQVEEGDEDLFTLSTMNGQAVLKLVKPLDYEKKFLHQVRIIASDRAESASQINTAVASLVVSVEDVGDVGPAFVSVSPVTRIREDIPVSSFVLQVRAVDGDRGINNPIHYDLMNEKDLFGIDSQSGIVFTKAPLDRESVKGGSYVLHIVATEQSKVTPRPSVETTVVVSLLDVNDETPTFKSESYLAEIQENSQAGVPVTFLGNSVAEVYDHDLGLNGTFRLRTEGDGGVFSVTPSEGINQVSFLIRVKNPARLDYERLKEINFSLVAEEASGEGFAKVPVTVKLTDINDEFPEFERNVYQVNLKENSAPGTTVVQVKAVDKDSGVYGTEGIRYTSLTGSIANELNLDPMTGLITVKKSNKTLLDRELSPVYYLTVEAQDNGGRGNRNTAQIVIILEDKNDNAPVFLQSRYEARIFENEKEFVSPLRFQARDDDEKETVNSEIHYSIVAGNEENWLEVDNLSGRVKVSKAFDFEKLPVSRSNPTSNVKRLNFTIRANDMGKPQQFSLSFLTLFVVDVNDNLPVFQKPYLLKTIREDMAGGTQILQTQAIDLDGSSPYNTVFYRIEHGAQDKFVIEPETGNVRLSPGTVLDFNVAPYHLLEIVALDGGGKQSERSQICNITIKDINNKPPKFEFNDLENSGQQSSSDSRGARGTLSGILTAGGGIFHARVLENSAPNTFITTILASDPDSSAVLRFTISFNASEARDERGILLRDVDLSQYFALDPVDGTLKTAGRAIDREMIESVKLAVVVEDIASATGPQRAYSIVIVQIADSNDNSPVFRKNPYYAAIPENTEEGTAILTVTADDKDLNRTIKYSLLPPKDDKDGVSFPLAIDPDSGVIRVTAKIDRESRDWLNFTVVAEDWGNTRRKGHATCILRISDINDNNPVFTDSISSIQVNENTPVGTVLAQIHAQDQDSGTFGKITYLLDRTSSNGKFSVDPETGKISVAEPLDREEQASYALVIQAFDNFRYGYATGESRNAFKQILVNITDSNDMIPKFEDDSSSDPNSCHSVTEFHEEAIITIRARDGDDESTSNAWISFKIKSGNELGLFKLEQGKNTAKVVPARSLKGFYGNYSLTIDAMDGGNPPNVATKEFKICILDFNDQKPVFISPSQNYTIRVPENATVGSTILQVRAVDSDIGNNGVVRYKFRQEFSRHWEAFNIDSTTGVLTLAQPLDREKQKIYHLRIEAFDLGIPTPLSSELDLTILVKNIDDYKPAFTLSEFVTQLTENAPPAKERIQLPATMDQDDEDEEEKKTSQVCYFILPKLSSNNSVKYFHLEPVTHILTAKVKLDREKQSNHTLMILATEDCIIDMTKLDVSSIEKTSLLVVQVQVVDVNDSPPRFIKKVFSGGVSTSTDYGTEFMRVAATDADSPPNAKLKYFIIHPITMSLSEGLSHLINNDNPLFNIDAKTGAISLAFDPQPDMKGHFVINVGVNDTGGLSDRCTVLVYLLRDDQKVKIVVRMSPLEVRQQAEVFTRTLGNVTGLIVNVDENFKYHENKDGSVDKTKTDFYIHLVHPKQNAVLEVQEVLKLIDLNIEELDDLFKDFNVLDTQGSTYVLAANKASEDTKSLFLVYATGSALFLALLLLVVISLCFAQRAKYQRQLKAATANAYGTSNGGFSERRKRKLSCYSYNNGYTNNNNSCSSSVILFEPAEFLVPSSSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLR6</accession>
    <name>A0A1D2NLR6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol-3-phosphate acyltransferase 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLR6"/>
    <dbReference type="STRING" id="48709.A0A1D2NLR6"/>
    <dbReference type="OMA" id="FFAYGDQ"/>
    <dbReference type="OrthoDB" id="5962536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT/DHAPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563:SF23">
        <property type="entry name" value="BCDNA.GH07066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="GPAT/DHAPAT C-terminal" evidence="2">
        <location>
            <begin position="129"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="573" mass="64556" checksum="6EFA5963D7BB8E2E" modified="2016-11-30" version="1">MTVASWIIGKTLGRIYPQILVRNAQIDVIRKARESGYPIVYLPVHRSHVDYVLVSWVLVACDLRAPLVAAGDNLNIPIFSLMMRSVGGFFIKRGLLSIVVDNLLAKKVEDVLVVPVNFSYERLLDGNFIREQLGRPKVSESFASAALGLWNSLQAKFGSARIDFGQPFSLREFVNAYQYDKVTPQLPLPLQNGYVAKAKAKLVQSLSNPSAAPSPNMDIDSVEQREMVNSLAKHVIYDGEKCFSMMSTNAISFILLNKYRKGVTTQVLAKEIELLAEEMLDRGYDVGISGNMEDVITHGFNSQLTVLGPTLVRQDRTATANGQSALIRPVTKLPNIIELAYYSNCVLPAYALEAVIATSVSVLSGAKRTEAESISIDENVLISTVLEFCEILQNEFIFAPPCTNLEDAVRSTVQYMTKQKVFFRTLLVAATFKRIPPTIILLQEHDKDMVHVDTKNQLERITFLTNLLKPIVDTYFTAACVLRCIVGFEIQEKQLQMDILTEIKSLLQHDSLTYGESLAMDPVRNFIKLMSGWEVLESYKYDRTTVYYLQDHFDCDKTIEEVIRRIQKYRDCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM58</accession>
    <name>A0A1D2NM58_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium-coupled monocarboxylate transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_00460</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM58"/>
    <dbReference type="STRING" id="48709.A0A1D2NM58"/>
    <dbReference type="OMA" id="RHADVTH"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051163">
        <property type="entry name" value="Sodium:Solute_Symporter_SSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985">
        <property type="entry name" value="SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985:SF2">
        <property type="entry name" value="SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN06175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="235" mass="24994" checksum="EA6E84486A21F649" modified="2016-11-30" version="1" fragment="single">FAYGAITIGFGFAAGGLGGVLRAALVVNGTVAGPLLGVFLLGVLLPFVNSKGAISGMLIAHAISLTIGFGGLAFGKHAVPLPFSIDNCSNETLSKVSNLTAVYERHFKALHAQPEVVEGFEKIFNISYLLYPLVGTFVTIIVGCIVSLLTGPSEMTKDDEKYIHPLVVKLIRMVQGKKPSASTVHATRKNDHEMSWRNGNGSSAGSWNNDMPRTNGKPIRIGGQSMYDNAAFQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0Q6</accession>
    <name>A0A1D2M0Q6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ceramide synthase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_20137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008331">
        <property type="protein sequence ID" value="ODM86545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0Q6"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="119" mass="13569" checksum="570DFD6904756B1B" modified="2016-11-30" version="1">MSKYAKKDRLAEGIFAIFMLTWFVTRLGIYPFYCLIPRSQLPVHISSRILDVGGIANYPSNSSRVLTYFVVKVVVNIFTSKRRKEINEVAQSLEARSARRRGYSSQKDTPMLSSTSNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1K0</accession>
    <name>A0A1D2M1K0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007003">
        <property type="protein sequence ID" value="ODM86845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1K0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903371" evidence="1">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="89" mass="9519" checksum="39230EE4329EBFB6" modified="2016-11-30" version="1">MDQLVTSTLAILLTIIVSTEGNPKDGPKGGPPKVNLTSIMANSQVTLSCITFNIESLPRAAGDNHRSTRSCAVIKGAIKTLWMNAMMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4D3</accession>
    <name>A0A1D2M4D3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004579">
        <property type="protein sequence ID" value="ODM87837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4D3"/>
    <dbReference type="STRING" id="48709.A0A1D2M4D3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="32274" checksum="B31B89E9C7C9130B" modified="2016-11-30" version="1">MTRTLPGAIRTEPGNSDQQQDDEAEVEALGIPTPACDEATLEALDNQAMGGMFRRVWREEEIPVDILGSCSNGVGSLMHLVRIKTSVEEADPENLYEGLNHKNCVMVLSDSFNRWFPTITVNYLERCSMWVTSTETEEEVAKKAARAMVAHVCRITGTPADLKKHDVLPPEETIHDSREPEEEAVDEKLVPCYGLRANKGAAAKSNPELAETDSFGLPLSMSGSSESDDSSDEEVIKVYETDRLLYKKYTLGMVLKDDKREAKVKDKKKKKRTDNSSTSGDKTRIMTVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4M7</accession>
    <name>A0A1D2M4M7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004530">
        <property type="protein sequence ID" value="ODM87861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4M7"/>
    <dbReference type="OMA" id="FINNIPM"/>
    <dbReference type="OrthoDB" id="93990at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="9821" checksum="7D1D38B8E1D6730C" modified="2016-11-30" version="1">MTDNFLLYDSGASNKRILIFGTMKNLRHMENSTEWFSDGTFKVAPLLFDQLYTIHVLRFQKVIPMVYALLPNRLETTYVKMLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Z7</accession>
    <name>A0A1D2M4Z7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004295">
        <property type="protein sequence ID" value="ODM87982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Z7"/>
    <dbReference type="STRING" id="48709.A0A1D2M4Z7"/>
    <dbReference type="OMA" id="NFTSTIW"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="114"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM87982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="453" mass="50661" checksum="074DF8B98F803F0A" modified="2016-11-30" version="1" fragment="single">MGYPTKDVNGNQEPSKLELCPGIYYYDIKHLTKKLCALGFSRLDLSIKEGRRFGTYPAFLKPVLNRTNLHIYRFAHVNKIHMGKKTNRAYAVTYKRHGHESFVRVKREIIISAGAIGSPKLLMLSGIGPKQHLESLGIECRIDLPVGRNLMDHISVPVGPFIVDTQIKTNVPGRDITLSTVAEYFSKRTGLLASAMGANAVAYIYSSLSKKRAEFWNKSPDIQLSLFPANPNIHEALEEVASVKPGLLRKYLRGLEEKDVFIVNVMLGKPGSRGDIKLASTDPLESPIMDPKYFSHPDDIRRVVDGMKFTVQLVENTEAFRRIGARFISRHFPGCEKYELTTDGYYECCARHMTFTVYHQSGTCTMGYGPEDPKAVVDSKLRVIHAKGLRVVGASIIPEIPNGNINAAVIMIADIASEFILDYWTQVDSSMRSRSPSPFINSGKQNKLDFIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M741</accession>
    <name>A0A1D2M741_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003181">
        <property type="protein sequence ID" value="ODM88789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M741"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045860">
        <property type="entry name" value="Snake_toxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57302">
        <property type="entry name" value="Snake toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903537" description="Protein quiver" evidence="1">
        <location>
            <begin position="25"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="15019" checksum="146DC99F1EE0E65A" modified="2016-11-30" version="1">MKMKQIILIVVVWLFLVDLQVAQGIKCYECYQCEDGWSGVEKECGEEDDRCLMTKDKDGGWINKMCTRKGTEDYAKIQKAKCDDFGKEGQKWCFCDTDLCNDMEISGSSGYSRRHLFFTVVVSFVVNFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M768</accession>
    <name>A0A1D2M768_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 9e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_17918</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003225">
        <property type="protein sequence ID" value="ODM88764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M768"/>
    <dbReference type="STRING" id="48709.A0A1D2M768"/>
    <dbReference type="OMA" id="WSNEIAI"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11056">
        <property type="entry name" value="CYP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000182">
        <property type="entry name" value="Cytochrome P450 3A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM88764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="530" mass="60629" checksum="3C83CD11FAD61F81" modified="2016-11-30" version="1">MLVAFVLLFVTCYLFYNLFLVKSSKPKWLGEQEINTSASFSTLDMLLGRKTVVDKDHHIYNSMGTKTFCVVDESPSPIILLKDLDLIKKAFIKDFDYFTDRRDFFTVSEKISFKQTSWHAERRGVEKCATNCQSYFYHRENKRMMVHFNGVGQQWVKMLAEKARDSPTGSAKIDVLSTVNQYTLEVIGNSVFGMRTGTIQDPNSIFAQKAGRIANMDRITDIIKLNLSPRYPQIFKMLGIEVFDKDAVQFFNDILRQSLEARLRGDVKQNDFQQLLIEARKGELKALGSDDLDSFEKEAEIRDNNSNTKLSDKSKILTDEVIIAQGVVFFLAGFTAVSNFISFAAYSLALHQDIQDKLREEVGRVVKEDGTLDYDDLAQLTYLDMVANEVLRKFPGAARLDRVCMKDYRDPETGLFVPKNTAVVIPVHAIHNDKRYYENPEKFDPEHFTPEKKAERSPYSYLPFGQGPRNCIGKRFAIIESQAAIANLVHNFRIDPTEKTPVPLQARFIGAQTFLPMNLELMLTPLRKQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7U4</accession>
    <name>A0A1D2M7U4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-xylulose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002950">
        <property type="protein sequence ID" value="ODM89043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7U4"/>
    <dbReference type="STRING" id="48709.A0A1D2M7U4"/>
    <dbReference type="OMA" id="CIEYLIS"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="26739" checksum="08E995ADB76BC256" modified="2016-11-30" version="1">MSLNYSFAGKRVLITGGAGGIGRQIVQRFHDDGAIVLALDKDSDAIEQLQKELPNVTAVTVDVADWNETKKAIEAFGAIDHVVNNAAILIPQYFMEITKEMADLHFNVNALACINVVQTAAKGMMERGSGGSIVNITSIESTGATAGFSMYSSAKIALEMITKSMSVELGRHNIRANCVSPNGIDGDGMVKISDPRITAAVENLFRRNTIKRLIAPNEVADLVMFLLSPLSAMITGETVVIDGGFMANFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M971</accession>
    <name>A0A1D2M971_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002613">
        <property type="protein sequence ID" value="ODM89481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M971"/>
    <dbReference type="OrthoDB" id="2311693at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="270" mass="30411" checksum="AB5AED1198DAEC64" modified="2016-11-30" version="1" fragment="single">YIEVAKFPGSGMREMDLYLLEDYQFEFKFERMGCLKNVRGAADFFLRDKKLSPRGQGVVSDKRFPWAVDYLKDSKETEMFGFNLSVSFEATLDETPPMLTTVVKGNFVDLLKYVYGISKALNCLKLTFGATLTLPGGQYCITVVRDMKTCTENGAVEFNLQAFWIKNLLKGFGNIAIPNPTSATMTVKLSAENKPISGQPTPVSSSGCLRLIVRETRSGKAKMNLSEEGLKAFLDFVYCFKLDFPKEHPRIAVELLEFAHEKQVSVSRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9L5</accession>
    <name>A0A1D2M9L5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002492">
        <property type="protein sequence ID" value="ODM89622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9L5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="190" mass="21888" checksum="49554CDB022C3F85" modified="2016-11-30" version="1">MNHYNCPVCFEIPKHDVSFVWTPYLFNIGNKDTGPLFLISGKVDISKGDLSFACYNLWGSELKVCEYYNLELTLHNERTSTQLGWNVHTFTLKEPSHMLKDFPAKTPLTIVNQILMDGDEDDVFFTATITIMDSRNPVKTGYKKLHSDIIPRNWGQSVSKEEAVVAEQSVNYKRYIFIVAAFWLGWYFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9T7</accession>
    <name>A0A1D2M9T7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_17028</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002479">
        <property type="protein sequence ID" value="ODM89654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9T7"/>
    <dbReference type="STRING" id="48709.A0A1D2M9T7"/>
    <dbReference type="OMA" id="LYYVVEY"/>
    <dbReference type="OrthoDB" id="5982258at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000104">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000093">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000394">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000498">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000719">
        <property type="entry name" value="nephrin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056754">
        <property type="entry name" value="DSCAM/DSCAML_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021012">
        <property type="entry name" value="Dscam1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050964">
        <property type="entry name" value="Striated_Muscle_Regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817:SF166">
        <property type="entry name" value="NEURONAL IGCAM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12355">
        <property type="entry name" value="Dscam_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25059">
        <property type="entry name" value="FN3_DSCAM-DSCAML_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="861"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="923"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="12">
        <location>
            <begin position="2"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="12">
        <location>
            <begin position="100"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="13">
        <location>
            <begin position="280"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="13">
        <location>
            <begin position="385"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="13">
        <location>
            <begin position="485"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="13">
        <location>
            <begin position="644"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="13">
        <location>
            <begin position="740"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1033"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1085"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1104"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1151"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1169"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1187"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1207"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1224"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1244"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM89654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1266" mass="138018" checksum="305F776315BCA37D" modified="2016-11-30" version="1" fragment="single">PPRWIVEPTDRAFAQGSDSRIECKADGFPKPTVTWKKAAGDGPMDYRDLKGSAPGMRVEDGALVIAAVPKQAEGYYLCEANNGIGAGLSAVIYLSVQAPPQFEIKFRNQTARRGEPAILQCEAKGEKPIGILWSRDGKRLDPKADPRYTIREEILSNGVLSDLSVKRAERSDSAVFACVATNAFGSDETSINLIVQEPPETPFGLKVLDKSGRSVQLAWNEPYSGNSPITRSRISNHGWRIQSPTATTYHLRLVAENEIGTSEASQSVTIITAEEAPSGPPQSIQVEPVDQHTLKVTWKPPLREEWNGDIMGYYVGYKLASSDKPYLFETVEFSREVGKEHHLMVSNLKTYTEYSVVVQAFNRVGPGPMSKEITQHTAEGKPDQPPQDISCTTLTSQSIRVSWISPPLASANGVIKGYKVIYGPASTWYDDKTKEVKVTAASEIILHGLKKYTDYNITILAYTNGGDGKASEAISCHTEQDVPGSPMAVKASVMSVDSVLLSWQPPSQPNGIVTQYTVYSRTIEPKESEPKAQKIPNFQANYEISGLKRKERYEFWVTASTAIGEGSASKAVTISPSNKVPAKIASFAEKITATHREEVKLPCQSVGVPAPEIKWKVKGQPLTQSDRLRLLPDGSLLIKEVQAPPQPPSISLSGTTGTSITVRLKSPMDSAPLHGMTVHYKQDFGEWETTQITPTTNEYTLEGLSCGTRYQLYATSFNGIGTGEASDILNTRTKGAKPGVPPAQKFIEVSQNSVTLHLSAWDDGGCPMLYFVVEYKARHQGEWTMVSNSVKPSGNYVVLDLTPATWYQLRVTAHNNVGFTQAEFEFATLTIMGNILAPPSREDSRDFASEWITFISGNLNLVVPVVTAVIVIFTALITICALRRGKTDNIHKAKIGPVRTNDYGRGMMELLPWLPEWVDYNMLIAGLAMVVIITVGIVVICVAVARRNRGPESVRLRDEGLYAQPDMRGMTLKREYRDELGYIAPPNRKLPPVPGSNYSTCDRIKKGQATWNPKRIAASAGGPHTYEELAGESTYYDGKPPVPPHAHDDSYSRPINGGPGGPDEEICPYATFHLLGFREENMDPSKLAQTLPHPPGHGHHRGGSQSAPRGTSTTRYGRGPVGSGVVSSVAGGGTVGPNGIVLPPNNVFSPEYDDPANIEDEYGYNSPNRRGSLGRRSMGSMRTVPIPESPSPPPPPPPRPTESGTPNSTPSHSQNNQSTNSANDSKESNELSEAECDRDPLIRNRNSIGGASPGSNTEEMRRLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAB8</accession>
    <name>A0A1D2MAB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dynamin-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16762</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002293">
        <property type="protein sequence ID" value="ODM89920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAB8"/>
    <dbReference type="STRING" id="48709.A0A1D2MAB8"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="80"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="595"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="547"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM89920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="690" mass="78469" checksum="72C8D335DE4F8A83" modified="2016-11-30" version="1">MHYSVGDTAPCNEEGINGFPMNLDPRERRRPIMNNPPKATSQPPKMPGLIENHELGTVMRKLNPLYDVYNKLNADGYRLDFNLPRIVVEGTQSHGKTSVLESVCGEDLLPKGDNIQTRCPIELQLRRSNEKWAEVSNDEGKRHTDMNVVRQLIQEHNAKIIESGKVISDDVLTVKLFSPHVVDLTLVDLPGLIEVAVKGMPEDLPSKISALVEKFISEPNSIILAVASATENVEGAKSVRMALNVDPLKKRTMLVLTKLDLSQDVNAYEALKGEKLSYDLGVIGVVNRSDSDIKENKSIQELREKEKDVLLKKFPLVAARNGVPYLIARVCDHLFRKVSDTLPDVKACIDQRIRKCEEHIISIGPEEDAECRRTKFIKYLNKFIDDYRGQINGKRRRPRPGQYPVHAFINSIFSHDFSLHLKKKEWTNQEISQILATTQAMHYDMHSIDTTDAFQAFASQKMQELKPLLLDCAKQVYDKMLKAIRTSFDPEADKRYPNLNSNIALCVTELCTEKFESLEEYLEKYIDSESDFSKFYDAEHDSDLDDAVAEDSQDGDDDDDEGDDNESGPSNVNEPAKKATEKVVDVPKDNFEDYWETVRSRVDKYFKKAKKGVKRHVPKAITSQLMYGVEQDLADVLFERLHRGHDKVDDLMRESESLLRERASTQETLEIYQDLKSIVDDSMESTTMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAI9</accession>
    <name>A0A1D2MAI9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002252">
        <property type="protein sequence ID" value="ODM89990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAI9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="45951" checksum="C9DC55AC629E6074" modified="2016-11-30" version="1">MEEAKPSSSTFTSCSSPRSGTELVEECITWSNLLPEVLELVFQELVCCKDDTSILTCRLINCHWKSVAESVMEQAVLSNFKNFSSTFRLIPRLSIVPSGGDDDRVLEKVRRYKFLQEENPKPFPSRSLLISPLNHDERHTGIKKRRSVSVIKLMTNFGHHLSSLTLDGVTLTSPNVLKVLLGEMKNLKALSLSRINLMTEDKHFREEKLTLAPPHLKILRLFSNIIVSTNQGFRRGTFNKWLATCFGSTLTHLEIDDAENLSFTPDNFPNLQVLTMYDVGTATLRNSEGLPRLQRMSIVHLSDEPGSKTCFKDLTRFLERFASTLIHLNLKFRMDEVKSEVVDFARIATPSFLNLKSFSYLFPSEDEKTELEEKGEQESDSKNFGRGRLLEQLSKIAKYSCVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCL5</accession>
    <name>A0A1D2MCL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RING-box protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001830">
        <property type="protein sequence ID" value="ODM90713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCL5"/>
    <dbReference type="STRING" id="48709.A0A1D2MCL5"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="7088" checksum="94994821053B56EB" modified="2016-11-30" version="1">MATSGATNDEMMDIGGAELDNNKNEKMFTLKKWNAVAMWSWDVECDTCAICRVQVMGKHSLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCV4</accession>
    <name>A0A1D2MCV4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein acetyllysine N-acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.286</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Regulatory protein SIR2 homolog 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">SIR2-like protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15871</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the sirtuin family. Class IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001785">
        <property type="protein sequence ID" value="ODM90810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCV4"/>
    <dbReference type="STRING" id="48709.A0A1D2MCV4"/>
    <dbReference type="OrthoDB" id="2919105at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097372">
        <property type="term" value="F:histone H3K18 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000038">
        <property type="entry name" value="NAD-dependent protein deacetylase sirtuin-6 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF1">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="13">
        <location>
            <begin position="353"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="117"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="143"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM90810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="724" mass="81301" checksum="5BD4CA340BA4939A" modified="2016-11-30" version="1">MDVNIPTERSAPAQPQYSTKSPSIGTSKLRKSRVATVKSSSSTSDISVRIKSENDGKPEDRENAEEDGIEVFRFDRNSLKLRCEKISPKQLNANTEARKNHLHLEQAKAKLKEGIKLEKHNDNSSSSLSTSSNFDSDSEESESSSSTSSSSSSSSSSSCSSSSCNSSSSSSDASSSSSSKISNNTVFNEESKKRTTANNKCITIPKKPDLAVTESIIANIVPCVNRIDPEPSGRGTISLGCDDADIEETINVEDLIQKRSKLRKNSRWADYVGGRKSSRLAPKTSFCNKKYEAQIKKRLMTLLKRSPTEWTDDERTTIQSFPQLVLEVSKLVEKRLHKKEIASERTKELEDAPEVLDMKCSQLASVISRARYLIIYTGAGISTSAKIPDYRGPNGIWTLLQKGEEVAQSLTDFSQTADPTFTHMAIKELWDKRVVKHIVSQNLDGLHLRSGIPKTALSEVHGNMYVEVCVKCGREFIRLFDVTENTRRHHHKTGRYCYHCGASLIDSVVLFGEKGALRWPLNWAGAEYHVDKADAILCLGSSLKVLRRYPWLWCMSKPAAKRPNLYIVNLQWTPKDQFAQIKINGRCDEVMKKVMGHLNIPIPVYERRMDTIFTIASMLHPLEKETTTSSELLYPHDLEYPEKNKDLRNYIRYEPVFKVPIPYENGHIRKPAQTEDNNDSDSNRSVKTVSVVKTKKRVLKGNNSSWLGNAVKSVNAKQKRKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME05</accession>
    <name>A0A1D2ME05_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001619">
        <property type="protein sequence ID" value="ODM91256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME05"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24255">
        <property type="entry name" value="COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24255:SF31">
        <property type="entry name" value="CUBILIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903868" description="CUB domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="53"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM91256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="190" mass="20934" checksum="FAC2B5F929BA085A" modified="2016-11-30" version="1">MGNYFFSVVFAAFTIWTTLQGTVFSASIKDGVRESRQISNGSTNATYEYGVGCGTIRVHPNYVIQIQSTNFGIGKYYNNDACTWTFTSDSCALSVYCPCFDIPSSLGCLEDYLKIGHLHFHDKFCGDNTPIGIYRATTDFLTLRFRSDYKGSGGGFLCYVRCTATGLADPIAPNVTCPNNTRNPYGNPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEG5</accession>
    <name>A0A1D2MEG5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional activator protein Pur-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PUR DNA-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001558">
        <property type="protein sequence ID" value="ODM91407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEG5"/>
    <dbReference type="STRING" id="48709.A0A1D2MEG5"/>
    <dbReference type="OMA" id="WAKFGST"/>
    <dbReference type="OrthoDB" id="523901at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032422">
        <property type="term" value="F:purine-rich negative regulatory element binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2450.30:FF:000001">
        <property type="entry name" value="Purine-rich element binding protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.700:FF:000004">
        <property type="entry name" value="Transcriptional activator protein Pur-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2450.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006628">
        <property type="entry name" value="PUR-bd_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12611">
        <property type="entry name" value="PUR-TRANSCRIPTIONAL ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12611:SF0">
        <property type="entry name" value="PURINE-RICH BINDING PROTEIN-ALPHA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04845">
        <property type="entry name" value="PurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00712">
        <property type="entry name" value="PUR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="30377" checksum="41598934B3BA4CE4" modified="2016-11-30" version="1">MWRKEGEGDDDANAWLWGLGQGEEQELASKMLQIQSKRFYLDVKENPRGKFIKVAEIGADGRRSQVYLALSTAAEFRDHLSSFSDYYASLGPPNPENVPEDGKLKSEVMVKTNRRYYLDLKENTRGRFLRVSQTISRGGPRSQIAIPAQGMIEFRDALTDLLEEFGTDDGGFRGELPEGRHIRVDNKIFYFDIGQNNRGVFMRVSEVKTNFRNAITIPEKSWSRFRDIFAEYVDKMKEDGKSGAGPSSATSEIPPTSTATSSSERDPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MER4</accession>
    <name>A0A1D2MER4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1</fullName>
            <ecNumber evidence="6">2.4.1.122</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Core 1 O-glycan T-synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Core 1 beta1,3-galactosyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">Ocin01_15308</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01001578">
        <property type="protein sequence ID" value="ODM91374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MER4"/>
    <dbReference type="STRING" id="48709.A0A1D2MER4"/>
    <dbReference type="OMA" id="SEGPKCC"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000017">
        <property type="entry name" value="Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF14">
        <property type="entry name" value="GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 26" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="17" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 26" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 24" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="25">
        <location>
            <begin position="89"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00040898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00041226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00042009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00043065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00059245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="ODM91374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="42892" checksum="708CABD627CADA35" modified="2016-11-30" version="1">MKQSQGKPGRSFIAPLFVGILFGFGFATVFLSIRNEPIEQSSTVLIQTSEIFESNSTSVLTSNDSTIKTHLDLQILDAKSLEKNVRVLCWVMTSPNNHQKAMHVKKTWGKRCNILLFMSSKEDPELPSVALHNVKEGRDYLWAKTKEAFKYIYEKHYDEADWFMKADDDTFVIVENLRLFLKDYEPKTPIYFGCKFNYSVEQGYMSGGAGYVLSKEALRKFITEAIPDKQKCYEDHNGAEDLQLGKCMQNVNVTAGDSRDSFGRYRFLPFLPEKHIIPGEIEKSSWYWNYLYYPQKEGMDCCSNGAVSFHYVSPNMMYVLEYLLYHLRPFGVSADKIDTQRESSSSSKSTSSEQQDFHEQAITDTANQGKFVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFL5</accession>
    <name>A0A1D2MFL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TOM1-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TOM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001451">
        <property type="protein sequence ID" value="ODM91692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFL5"/>
    <dbReference type="STRING" id="48709.A0A1D2MFL5"/>
    <dbReference type="OMA" id="GNHKSDM"/>
    <dbReference type="OrthoDB" id="2018246at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14233">
        <property type="entry name" value="GAT_TOM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03565">
        <property type="entry name" value="VHS_Tom1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014645">
        <property type="entry name" value="TOM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13856:SF137">
        <property type="entry name" value="GH05942P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13856">
        <property type="entry name" value="VHS DOMAIN CONTAINING PROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036948">
        <property type="entry name" value="TOM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="5">
        <location>
            <begin position="37"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="6">
        <location>
            <begin position="253"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="421"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="522" mass="56345" checksum="CA77FA0D656886E3" modified="2016-11-30" version="1">MTAASLLVSSRKLRQRTRSCRFLVAFSTPIGQKIEHATDAALASENWALNMEICDLVNSAEDGPKDSVRAIRKRLQQNAGKNYTVVMYTLTVLETLVKNCGKRFHILVCQKDFGQELVKLIGPKNDPPTIVQEKVLGLIQSWADTFRGQPELVGIVQLYEDLKSKGIEFPMTDLDSMVPILTPKRCRDRADFASSQPRRKTPTSTTTTSTTTTTRATTTTTGTNASSSTAETHGQSNNDVTAIKPPQVKVTPEQLVKIRRDLDIVQGNMAVFAEMLSEVKPGQEIPSGDMELLEELNTACKEMQRRIAELLCTVSSDELTAEMLHINDELNNLFLRYGRHKKNIEKTSGSGGSQPTGNKDEPSLIDFGGGDQSAANLASKIGALNVSGGNPSSGAIPKTTSHPKKEPDDFDMFAQSRGATYEKSKTSGSTYADNTNVDQKVGNLGDAARNKEPLETHRESDFDEMEAWLNANPPAGAVPSAAAAGTASLTSSEFDKFLAERAAAAASSPASGAGGSTKLDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHR0</accession>
    <name>A0A1D2MHR0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein sleepless</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001208">
        <property type="protein sequence ID" value="ODM92529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHR0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904043" description="Protein sleepless" evidence="2">
        <location>
            <begin position="28"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19573" checksum="3BE78B359219F002" modified="2016-11-30" version="1">MFMPTTKPTSLLLIMAVGAILSNGVHSTHSRAKCYECIDCTKPRYATECKEEEVQCVTTVMEDGEINRQCAREEVKKQWADVGITCETYGSPPQGNGNKLKACFCNTNLCNTHDDTMLAILTISKLNCLLSDLRILFRLPLRSPPVKVFYFIILALITPISPLKYWKYIIGSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK28</accession>
    <name>A0A1D2MK28_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Activator of 90 kDa heat shock protein ATPase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001009">
        <property type="protein sequence ID" value="ODM93369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK28"/>
    <dbReference type="STRING" id="48709.A0A1D2MK28"/>
    <dbReference type="OMA" id="GDCEVNQ"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08892">
        <property type="entry name" value="SRPBCC_Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="ASHA1/2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF22">
        <property type="entry name" value="LD43819P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="2">
        <location>
            <begin position="29"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="341" mass="38095" checksum="6FFCFF381AEB7D13" modified="2016-11-30" version="1">MAKWGEGDPRWIVEERPDATNVNNWHWTEKNACQWSKDKLKELLVGLKLDNKVGSCKVTELSKCDGEASANNRKAKIIVFFEWELRMKWKAKVPGEEKSIEGTIEIPNLSDENTVDDLDIQFLTEATSKAAQLMKEALRADGTPIVKASLQSYIDALKKEYTQGMILPSKEQVSSNTNKLSDLRLDSDKGAGKNGLTGGAKNTGVKLELCNLKSSTSMKCTAIEAFNALTRPEMFAAFTNGSGRIEPKVGGTFELFGGNVHGKILEIQAPTVLVQEWRLKEWPDGHFSKVVFTISEKDDSTDISIEQTGIPKSALEKTREGWERYYWDAMKRTFGFGSFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKE3</accession>
    <name>A0A1D2MKE3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">B-cell lymphoma 6 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13205</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000975">
        <property type="protein sequence ID" value="ODM93477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKE3"/>
    <dbReference type="STRING" id="48709.A0A1D2MKE3"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="18486" checksum="5A09ABCBA4ADFC80" modified="2016-11-30" version="1">MDNHLKAHTRSVHLKLKPFKCEMCEMTFAAKGDRDRHIYTHLAEKRHKCNLCSASFVHYSGLYRHFKLHKKKGAIRCKVCVCAMLFISENQLRAHNIMRHNADSKCVFCDKTFFDYGTLKKHLRIHTREKVYDCKGCNNSFLSYEQLLYHKCLQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKF8</accession>
    <name>A0A1D2MKF8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001003">
        <property type="protein sequence ID" value="ODM93385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKF8"/>
    <dbReference type="OrthoDB" id="8294900at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="405" mass="46714" checksum="0419864D7C4B6F28" modified="2016-11-30" version="1" fragment="single">SERKASFLQRSASIASLVAWRGRFQGKLSKRANFKSYISGHEGENEVQETTLRNDDPTSFPEDKPSHHQCEATSPNKKEVSCTDKDCTELENYFKKKLPITTRSSCNVSREDQRKMRKSVYKWMNDLPEENNLEEFLEAYGIPVEGVDMEEFKRRLKTFLEERLSRVAPSTPTPSETGFLYYKLTTKHVEETTTEQQWHPERQLKVLGELAHEDNLEKWLESLDVPFFGSIPETKEEIRKYLKRNPDQSVVIPAPTPLQDKVVVPKWQELVENMRGLKNEDELEKWLDSLEVPHNVPTAKVKEEIKKFFMHETYDNFPDAGLLKQVAVIAGTTAALGVLAVVSTTLLSFAMPAAVVFGTPYFVEVFAQYFLQRQEVCFSLLNFHTQNAKPLSTAWAKQYILWKYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLU2</accession>
    <name>A0A1D2MLU2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor AP-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000893">
        <property type="protein sequence ID" value="ODM93898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLU2"/>
    <dbReference type="STRING" id="48709.A0A1D2MLU2"/>
    <dbReference type="OMA" id="TQPHHVT"/>
    <dbReference type="OrthoDB" id="10029128at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="20"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="33617" checksum="1B2F5E2E3690FD9E" modified="2016-11-30" version="1">MDSLPLSPGDKEETEEVRRHRRLVANSNERRRMQGINNGFEALRGFLHCGDEQKLSKAAILQKTVTYIQQILNEKSDLIMRNAQLEKMVTGGKVEETPVFCPARGQEVFVVSTTTDHAVPIIKQEPLTERRRKRKASTAQLENVDDEGVASLYSSEHSGSGEDLQSEVAELREETKRLRLSLENERLHRRNLEGQIRNLQMQNQSLTETARFAQDQYTGKMSNLCPTTPGVIVHDETPRCRTVSRNNLESIVEAIRRLEGDHLFADDDDHNLTTPSPGSPSAAVEEVEISATEEYITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMA8</accession>
    <name>A0A1D2MMA8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000874">
        <property type="protein sequence ID" value="ODM93991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMA8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="23" mass="2592" checksum="7C7A87C6A8530E6E" modified="2016-11-30" version="1">MYSLIYVLALRIHSSRPSTLTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMD1</accession>
    <name>A0A1D2MMD1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12457</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Golgi apparatus membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasmic vesicle</location>
            <location evidence="11">COPI-coated vesicle membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000839">
        <property type="protein sequence ID" value="ODM94226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMD1"/>
    <dbReference type="STRING" id="48709.A0A1D2MMD1"/>
    <dbReference type="OrthoDB" id="10266042at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051645">
        <property type="term" value="P:Golgi localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1170:FF:000007">
        <property type="entry name" value="Coatomer subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000003">
        <property type="entry name" value="Coatomer subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000024">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="13">
        <location>
            <begin position="620"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="518"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="531"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM94226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="862" mass="95716" checksum="CDFEAE59BC35B9D0" modified="2016-11-30" version="1">MHSKNFVTPVANQFVESNPFVVAPRVSFAAMSITGTTNPSNMYSTLSVTTVAPFVAHVTLNRPDKLNAMNRAFWGEIRECFEKLNDDPECRTVVLSGAGRVFTAGLDLTDMSDFFDIIQSEQDIARKSKLFYNKVREYQNAFTALEKCSKPVIAAIHSACIGGGVDLISASDIRYCTQDAFFQIKEVEIGLAADVGTLQRLPKTVGNDSIVRELAYSCRKLYSDEAKSLGFVGRIFPDKESMMSAAIDLATVIANKSPVAVQGTKINLNYSRDHTVDESLEYEASTLELNNASKRRFSESCHGPNTYMYKNIYKDFVNLNLQTTDSSILFRPIRQKNIIFYQNIVTTMVLIAAAICTKGGKTLLSRQFVEMTKSRIEGLLAAFPKLIPSGKQHTFVETDSVRYVYQPLEKLYMVLITTKASNILEDLETLRLFAKVVPEYCKSMEEGDISDNSFNLIFAFDEIVALGYRESVNLAQIRTFVEMDSHEEKVYQAVRKSQEREAMQKMREKAKELQRQKLELSKRGIKGGTGSSSYSMSSSSYNSNPSVIPEASSVPIEPSRPSYSKPSGPSKALKLGSKSRDVESFVDQLKSEGERVPLNEPSNNVNNKFSSMSPQQQANTESVHIKIEEGITVTAGRDGGLQNMEVHGTTILRIQDEAATQIRILFENEDARGIQLQTHPNVDKDLFRNKHQIGLKNPQKPFPVNTDVPILKWRYQTTDETQIPLTINCWPSENGSGGCDVNIEYELLIDDVELQDVVITIPVPGGSGGPVVGECEGDYIYEARKHCLLWQLPVIDSSNKTGAMEFTVAGGTASQFFPVQVSFHATQPFARLSVADVVSIDSGSSVKHSVETLLSTKTYEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNS0</accession>
    <name>A0A1D2MNS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta,beta-carotene 15,15'-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000763">
        <property type="protein sequence ID" value="ODM94719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNS0"/>
    <dbReference type="STRING" id="48709.A0A1D2MNS0"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003834">
        <property type="term" value="F:beta-carotene 15,15'-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042574">
        <property type="term" value="P:retinal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF132">
        <property type="entry name" value="BETA,BETA-CAROTENE 15,15'-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="533" mass="59161" checksum="9533C6A21AC1EAF6" modified="2016-11-30" version="1">MVESNGNGVVESAYPPNLQNTQEIPDGANAVVSGSIPSWLKGSMLTCGAGMFHFKEGSVKHLLDGMAMLSKISINGESSTVSVVQKYLKSKAFERSMEAGKPCTTLMGTPFVVQPLRPFGPYEFTDNCLGPLHEENKGEIFLQSDGSTYFFQIDPETLEPIEKNHYLKMFSLYSMRPLPLEDENGDLYNLGGTITGSLQCQILRMKKENRSKPLKERWDIICQIPSRMKTSGSILRCFGMSKNYVVFVEQPAVVNAMKMTATYIKQYAMMDWLEWHPDFCNRFHVVSKETGAVIKTEFLSFAAFYGVSILNAFEDGNNNLVVDCIALPNTDIMKALLLENLTSPDESMGNIYSGSIVRYVIPLIEELGDADDNDNYIEDDYDEAQAIRKGDKVVLIPEVITIGVDFAIANKNYTGKPYKYAYAINSYARKGAEVGNCVMKVDLETQETKYWKGLEGQVPSYPIFIPNPDAESEDDGVLIFGVTAGIADNNENEAASANSVVFMDAKSFTEIARASFKDKIVAAWIHGIFLPQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPA0</accession>
    <name>A0A1D2MPA0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000767">
        <property type="protein sequence ID" value="ODM94691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPA0"/>
    <dbReference type="STRING" id="48709.A0A1D2MPA0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="537"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="600"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="657"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="697" mass="76387" checksum="4ABDC3293D70FF8A" modified="2016-11-30" version="1">MKPTRNKGGSKNAVLAIGKPSKALSPPKLETEAEKEDENEPYTPWDEDEKSEVVPDSAVPSSSSTSTPLLPAPSQSGSAVIIETQKQLEELEAQIAKQKEDIVSILQGAAKNVVGIPGLDGDFPESLPEDNAAAESQNKQDVPVFLRPTPVLSSLDPRSTRSSIFKHQQLTVNTTKVPATTIPGLDLEIRESCGDDDVVVIEQEENSKSHHSLKPIPEVAVDAPKEVENSAEEAYSPSAMDFSDDDVVCEDDDLLSNTTQKVPDDKHVKDNKTGGRFMFGQSSDDSGVKEKIDAKNAESQSKEPLIVDLDERQTEEIKIILSKINTPVIPIAHHSSSEKHVGLLNKTLLDGTVDLVDDSEPPPPGENSAPSLPPLSVSPLTKSSKVFDDSPFEKSPLLTNNQSRVKININLSTKMLPLSTSKKEIDKNSASFAVDSSEPSLDCPVEPTMFKDIDERILAKEGLPPPIIPETIPLPPVDFKTVPPPVVINQPLTTLVPSVPLHIPPPPLQSSSGSVVINLNVPPPPFITIPPQLTGIRFPSTQAPSAQQVAAPTFLSRPPPSTPPRNQFSPIDTSSSSGRQSRTGPGPHSTLFKSMSSSPKEAEDRGMTEKDKDDRNYLARQDKGRGSYSQDRRRTHDRVERVKRNRSRSKSRDRSRSRSRSRSRDRKRRRRHSRSRSPVRRSSRRNRSRSRSRSPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPI9</accession>
    <name>A0A1D2MPI9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidate cytidylyltransferase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000765">
        <property type="protein sequence ID" value="ODM94695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPI9"/>
    <dbReference type="STRING" id="48709.A0A1D2MPI9"/>
    <dbReference type="OrthoDB" id="341477at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015222">
        <property type="entry name" value="Tam41"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09139">
        <property type="entry name" value="Tam41_Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="134" mass="14908" checksum="EA0874425F9D3860" modified="2016-11-30" version="1">MTLPVPLQISLAKQHFRDPRFFDIEDIMGELSYLPDLRLHIRTSISEIVRASSIQQTLQGVLTAGVFKSIRYAADKMKKRVEARAHTPLQALPPATESEDKQTPIQGLSTASNNKHNTGDSSKAEKGKDMQPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPS7</accession>
    <name>A0A1D2MPS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Venom carboxylesterase-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000710">
        <property type="protein sequence ID" value="ODM95110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPS7"/>
    <dbReference type="STRING" id="48709.A0A1D2MPS7"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="91"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="269"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="461" mass="51738" checksum="45F8D9EFD3CEDE6E" modified="2016-11-30" version="1">MEKVPLNSGGKSEYGLIETDIRVKNNSNPVSPKGFLPTKFWTRVIPAVGLVTLVCVVAFVFFRSSGETLTPIEENLQATAELETGAYIDLEAKQGRIRGYVRNTRQGRNYLAFYKIPFAQPPVGSLRFQEPQPAGSWEGLRDVNEVAPQCLQRIKYSPVVEAGGEEDCLNLNLYTPSVQNKSAFQLWCFTDGNGSRYGAEYFLDEDVVLITIHYRLAAFGFLNSEDGVFPGNVGFKDQLMSLRWVKNNVAEYGGDPERSGASVCNTLDLFSDNPLQRLREVAEELNCPSNGTTAEIMECFMSKPPSEIAIARPSTENGHFAASIDTNSPSVFMPDSPYKILKDKKANSVPYILGIVTAEWLFDALAALHDPELYQFPYYGYLEIPFGDPEYYNFSEYFVKLWAQFAATGNPSGMNGLEWQSSPSREGAFWFELNDSPGRTHILDERMQFWDQFTDSQLKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQF2</accession>
    <name>A0A1D2MQF2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative bifunctional chitinase/lysozyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000684">
        <property type="protein sequence ID" value="ODM95330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQF2"/>
    <dbReference type="STRING" id="48709.A0A1D2MQF2"/>
    <dbReference type="OMA" id="TYINNIR"/>
    <dbReference type="OrthoDB" id="8248922at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06543">
        <property type="entry name" value="GH18_PF-ChiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052750">
        <property type="entry name" value="GH18_Chitinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42976">
        <property type="entry name" value="BIFUNCTIONAL CHITINASE/LYSOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42976:SF1">
        <property type="entry name" value="GH18 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904385" evidence="1">
        <location>
            <begin position="22"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="24"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="313" mass="33805" checksum="47CA12C7309D57DD" modified="2016-11-30" version="1">MAIFKLLVAIPLLVSIGTVNAAGPKFAPYFDVTFLDPGLPTISSRSGQNDFTLAFVLGGTEGCVATWASQFALDDPTILNPIKEVQSRGGEMILAFGGALGNYLEHRCTSAADLANAYKRALDIVGSNHLDIDVEAPIDLNIVNGALAQVQRERPQVTVSYTLMVQGDDYGVTPSLGVDVLVSAKALGVRVDVVNAMTMEFPSSKPSWGDAVISAANATLYQMKEIWPEKSDQELRKMLGVTPMIGRNFNGKKFETSHGRQLVDWANENGIGFLSFWSSGRDNGGCNDIISPTCSGVEQGEFEFIRIFQNFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQP7</accession>
    <name>A0A1D2MQP7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="2">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11356</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>glutathione = L-cysteinylglycine + 5-oxo-L-proline</text>
            <dbReference type="Rhea" id="RHEA:47724"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58402"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="4.3.2.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.7" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000684">
        <property type="protein sequence ID" value="ODM95326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQP7"/>
    <dbReference type="OMA" id="RYWGKVD"/>
    <dbReference type="OrthoDB" id="544697at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061928">
        <property type="term" value="F:glutathione specific gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904394" description="glutathione-specific gamma-glutamylcyclotransferase" evidence="5">
        <location>
            <begin position="26"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="29181" checksum="988D03A51F3B0017" modified="2016-11-30" version="1">MISVFNHSFCIYFLLILILTFPKLSIQRTINENELECNPKGDSQKDQYIVGYGSLIKTFSKNRTYKNTGENMPVLINGYSRVWNCKGVSASLSTTYLGIVPKQNGTLNGVVFKIPNSNALEAYDERELFYCREEVDRDKISLLVSSSQTPANLPSGQFWIYVTKPQYTAFPTSEFPIVQSYVDTFLSGCLEMQGKHSLENFADDCIKTTEGWTNPWINDRIFPRRPFVYEPDAGKIDKLISKHLPKHFKTIKVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQP9</accession>
    <name>A0A1D2MQP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000680">
        <property type="protein sequence ID" value="ODM95383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQP9"/>
    <dbReference type="STRING" id="48709.A0A1D2MQP9"/>
    <dbReference type="OMA" id="CQEIRIN"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="774"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="617"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="881"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="976"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1173"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1214"/>
            <end position="1235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1273" mass="133736" checksum="56BAE2B283D85502" modified="2016-11-30" version="1">MVRVRRNPSTTATSYKNSKSSCNNFSKYGSSRLPSIPEISLTEITPICSNESLGFELGLSEIEELDEENANKVVIAHQSEAQNDRFSTAVISSPQINWTRSINNNTHISRIPHFIHPESNQRYEAVKIEKGVETVVFKAKVGADDKASTSSKGTSSKKRESKTSSSSKSTSEPGKTPKPTKATKSSKHEKIPDKKLEETGEIVDYDQISLDNEVESTNKTRSIGAHRDTIFSKNTETTEGASWFGHDRGFSFDSGYDNPSLNMPNNYAPPYSPFPPDPSYYQFGYPTPPPPPPTYFGPPPFGFGPPAPPPQPLSNNCPCPSSIQNSGMCQEIRINVDKVPPEVTTRKVPCPSGNGTTNPACQQPVSSASAQVCDPLTPVQVTCTPIMCSVIPPNCSNSCNQSSRPSCRCGRFAPIRNPQCTACQRCRVLKYCKSIITVSRKERTSVQMGGGGGGTCDCGSSQNYNGNNNGGGSGGRNNESEYSSKFKDWSKETPDNQKRREGSFGSGKNEGANGSPDNSAGGRDANGNEIGFDQNRRDSNGTGPEGLFGDSNRGTQNPNNFGASGSGESFGKNWSILPDGSIVPNGAGTMGQSESRALGQNVNGTGAMGQNAGTNGAGSNRNLPNNNSGNPNEYVYLLDPNGNLISSSGPGNNANGGNNGVINGTGGPNNGFNNGPYNGYGNELGGPFGNNGYGLVGGPNAGSGPYGPYNGYGNGAGVNLLTGGNGIGGPPNAYGPYGPGGQFPFGGNQIGFGPGGDLRNGYINDPNYRGGPLGYGNRDSLNHKGGIPKVHKSVGPDKFDDGWDWDKDPYPFGTPFKGNRRSADYPGKHGNGQNPGPGHGHDPAKGHPFGPGGPNSNRNPHAGNSNGPGAYHGNPNGPGAYHGNPNGPGAYNGNPNGPGPYHGNPNGPGAYHGNPNGPGANHGHPNSPGAYHGNPNGPGAYHGNPNGPGEVGAPGYGQIPYGNPNGQSPYYGHPNDPNNNRGSPFQNPYTSDPRFQNGSGYPNGMGNNPYHGPQSILGFHPQHPHNGHVHYPSSDRSSNFPSRAGDHPGGHVRGSNDNGHNPTHDKSVGPGPWGPWGRDWPGRGRNPLIAPFKSNSKNKGTNASPSPHAKKIKDGSTGEDDPDRYKSFGSSSGVVYDPNKDGGKIHGKSTKKPSGGSGNKHHGPRASGETDHTSSSSENSTMMLVKTITEVRKSKLMSRDDEESSSPSSSGMSPPSPHPSPVPSPPDSPPKPPKVGAPKKPQARRISDESPPRQKRKSREIHLEDSDSDDSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSR8</accession>
    <name>A0A1D2MSR8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000574">
        <property type="protein sequence ID" value="ODM96140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSR8"/>
    <dbReference type="STRING" id="48709.A0A1D2MSR8"/>
    <dbReference type="OMA" id="RFAMYDY"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37151" checksum="DC96BDC0ADA0EA10" modified="2016-11-30" version="1">MRRELAFASNVKDPDADKSIIQISQEYGYIIETHNVTTSDGYILTLFRISGGRRSPAREGKPAVLVLHGWGNSCDSWIALPNDKNLAFFLADNGYDVWLGCHRGTSFSRGHITLNSNTDIRFWEFSFHEMGLYDFTAMVDHARMGASAFLVATSEIPSMNEQIHAAYLFAPGAFEGGLYEPITAALLPIVGTPTEVKNLLNLNRDCCTIYSVGDFHSETPFNSALGIGRLAICQPKAIRCGVCDVYTLAPYYFNRAQTNYTNLPRMIAKLLDTGTFRSLFHFGQNARSCMFRKYDYGTRENFNRYGAAEPPSYNLSGISVPIFLSSVFSYCTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSW7</accession>
    <name>A0A1D2MSW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 13-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000596">
        <property type="protein sequence ID" value="ODM95988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSW7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904490" evidence="2">
        <location>
            <begin position="25"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="9730" checksum="984CD832C7204B27" modified="2016-11-30" version="1">MAQNDYKSLAVAAILFLVIAQTLTAPSGMTIASAGSHGASASAGSGDTLAIANAPLNPPSSSGSGVFTRSGGSPSSGSSGSGGTTILTQDGDKPAKVYKISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT29</accession>
    <name>A0A1D2MT29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CUGBP Elav-like family member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000614">
        <property type="protein sequence ID" value="ODM95845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT29"/>
    <dbReference type="STRING" id="48709.A0A1D2MT29"/>
    <dbReference type="OMA" id="KPYPSIP"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000013">
        <property type="entry name" value="CUGBP Elav-like family member 1 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000198">
        <property type="entry name" value="CUGBP Elav-like family member 6 isoform X3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="15"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="102"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="316"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="399" mass="43355" checksum="FF3A58CF8EBBF381" modified="2016-11-30" version="1">MMTTNGNDMPDPDAIKMFIGQIPKSWNENDVRMYFEQYGPIYMVNVLRDKVTKQSRGCCFITYFSRKSALEAQNACHNLKTLPGMNHPLQLKPADNENRAERKIFVGMLSKKINEMDLRAMFCRFGLIEECSILRDGSGQSRGCGFVTFSSKLCALNAIKVMHHSSTMEGCSSPLVVKFADVRSKEKTPSVVSASMPTVLSSLSDTKVFSMLQQHQRNTVLSQAPTFSLGNIGSSIPGLSNLPSSTTDLAALTFLTNLAASVNPTGTGHSSLLTSGGNSSSTASLSSRTASAVSMGNGNFSTNGLFSNQGEGPDGSNLFIYHLPQEFTDADLLQAFLPFGTILSAKVFIDKGTNLSKCFGFVSYDNNLSAQLAIQAMNGFQIGTKRLKVQLKRSKDKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTG4</accession>
    <name>A0A1D2MTG4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNL-type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000544">
        <property type="protein sequence ID" value="ODM96390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTG4"/>
    <dbReference type="STRING" id="48709.A0A1D2MTG4"/>
    <dbReference type="OrthoDB" id="512667at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="5">
        <location>
            <begin position="117"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="202" mass="22447" checksum="0F8F6A556F120D39" modified="2016-11-30" version="1">MHRLRQLSSTPCIYRALVKSADCNATCQVRRLMHSSSFTNFTGGGWTKTDCLSVTVTSYRSSLLRNQYFFIQNGHSCWSRLLCTKAVVPKGEPESGTKDSKTKIQVDSKNEVLGSVGPSPKLYLSFTCTVCNGKNSYTISKKAYHHGVVIVTCQGCSNHHLIADNLDWFSDIEGNNIEEILAKKGEKVTKFLASDVKEIEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU51</accession>
    <name>A0A1D2MU51_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Speckle-type POZ protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU51"/>
    <dbReference type="STRING" id="48709.A0A1D2MU51"/>
    <dbReference type="OMA" id="GSENCQH"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904561" evidence="2">
        <location>
            <begin position="25"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="344"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="520" mass="59023" checksum="4C1B5CE176423A22" modified="2016-11-30" version="1">MGTQIILYFQVLVILVFCSKDVLSESKVSNDNDVDTSSSTSTLDDITSNNTRCSQTHLSFTKETLLHIWEIKGLLGYISYIKRFDQPFELKTDHVSFKSDNVDGKWIFKVLKVRHNPPFAIPSPSTSPSNADTGDVRIMATYSYEAKLPRKIDFLIHLTLIHGHKEIVLPPQRSTSPIIVQQRYYNTRGYQLNSNFFEYVYTFTWKDVIHPLDSLKTNSYHSKYHIGQQHQATESHNPHRHDEDASEEFFEEFTRSDFSGHFGDVTMKFVISAYFPGDPVSISSSRCNASLLELVSPNLMEKLASSSSSGASGQNFHKDNTQKFQGAPPYLRYTNSMLHDDRFADVILVVGQDEVPAHRIILATSSPAFSEILENTTVFYTSNQTSTAANCQLVHLPRILIEPQDIGLDCIHELLRYVYTGTVDNSKMTEGLANRLIIAADKYGLPELKRLCENIVLQGLRAENAIELYLLGNRVSSSRIIRKALSIMKLNKAKLATQTEDFRQLSLRHPKLMYELFLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUH0</accession>
    <name>A0A1D2MUH0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysosomal-associated transmembrane protein 4A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000525">
        <property type="protein sequence ID" value="ODM96572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUH0"/>
    <dbReference type="OMA" id="KLAYLMP"/>
    <dbReference type="OrthoDB" id="10002163at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051115">
        <property type="entry name" value="LAPTM_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12479">
        <property type="entry name" value="LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12479:SF10">
        <property type="entry name" value="LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="31381" checksum="4899D5D24704C507" modified="2016-11-30" version="1">MIAEHFHFSDFDKGGRLVSKQDRRSNRNWKTCCCCLQVRTVTISIGIWDLIMDIMVLSFSVALLTYDFGQGQGQDQEGSTGGVMTVTAIPVPVPDRMLPIPRSKSELLNKLDNLRQIRLERMEYVQEASKNASLHVIPLTVINMLMTLLMIYGAARGKLAYLMPFLVLRVTIFCIFCVTTVYYIPSVTELIMNPKVKFPLPMREEFVLRWDPPWGPFIIVLFMTVLILVKACIIGVIWKCYKNLKSKSGRHEDPTCSVMGLHQNFLHGGPDCDIDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUI5</accession>
    <name>A0A1D2MUI5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000527">
        <property type="protein sequence ID" value="ODM96558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUI5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="217" mass="24136" checksum="8F563C7CC39C002F" modified="2016-11-30" version="1">MDAPEFAAAFRKLHFLKLECNTTSNNADTLKYSLKNHFNTAVIDIIGSLDENANSIELEALDSSKNSKGSKLFRVTIKKDVDLLEYDTQCDLMSMTGQLISSITMKDMGLSTYNYNVLNSAGAALFQVSKKQIQPGHNEFQITTVTGCVTARIDIHNGKVLLSMTPELDPFSKVTFVCLMMLMDLAENQQNEPQPSKIESASAMDTRKFYTNQKLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUZ6</accession>
    <name>A0A1D2MUZ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000488">
        <property type="protein sequence ID" value="ODM96920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUZ6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="67" mass="7503" checksum="ED2B7E4A88FEBC3D" modified="2016-11-30" version="1">MEMGSCPMVDRGLLRTSHSSTLGELELPYPDLESQRARNRLESKGVESETEGIGFQPAIEPKRQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV24</accession>
    <name>A0A1D2MV24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000505">
        <property type="protein sequence ID" value="ODM96761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV24"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="489" mass="55053" checksum="8F282E6ED1D0F181" modified="2016-11-30" version="1">MRLFHPKNLYKSIYGCTKGAGRIKMKRTHSFCKAIYASILQFSRSISFKSRHVLPFAVKMEPTDNQPAGAELISLVLHYLNAEELRAARLWNTAVNQIITNDPKLLWAKNVIQIQIDALQTNAKLEWVRLRLLRLITLYNCPNFHIVKTSLLSSEALDFFQSSVRYQMKYLKITKCQMSTEVLLHILACTAKHLGHLEIRDFSQFVQSSGNLFPKERRGPNLSNLKTIILDNNAFSDDTQISSEGDDQVSLSFVKKVLEKSINLESIGLLGWNATSCHHYVKVLAALPPGNLDNVQTFSLSCNVDIALNIKSQYDFLRELQWIRLPNLTRLTIDCNLPLELATGLTGSMIEDFTKSLAILLEGATETLEMLELINCPVTNEVLRIGMNSFPNLSKVDTSGSMITKLDPNGNATPRYKIPLQRKPGKSPVKSQIRYAARLEETDGGTPESTRYEVYEILCGIILAAMLIHFGATSVFRPHFATMMEIVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVK4</accession>
    <name>A0A1D2MVK4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_09689</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000480">
        <property type="protein sequence ID" value="ODM96982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVK4"/>
    <dbReference type="STRING" id="48709.A0A1D2MVK4"/>
    <dbReference type="OMA" id="CFESELW"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000004">
        <property type="entry name" value="Glycoprotein 3-alpha-L-fucosyltransferase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031481">
        <property type="entry name" value="Glyco_tran_10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17039">
        <property type="entry name" value="Glyco_tran_10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="40"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="176"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM96982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="386" mass="45241" checksum="5F17D9FA0E4035EF" modified="2016-11-30" version="1">MRFVAAAFVIFAVLGWAYFLVSIQNPKHHSYIWLNEAGDKALVLFWTPYFGVRNGNPHKILSIAKKSYPEECFRNCEITFDRKRIKEAHAIVLHERDMKKSDMPEIRAASQLWVFLAQESPIVTTNILKTFPGVFNWTMTYRRDSDVFHPYAKIVPKHELNESSTRETVELNVFLAGKTKLVVGVISNCFTNSKRENVIKQLKKQGLTIDIFGKCGSPTCPRGGNSSCFESELWTKLGKEYKFYLAFENALCWDYVTEKFFRTLEYGLVPIVYGGADYNNIAPPNSFINVENFESPKELANFLKKLDKNQGKYRKYRKYFQWRKTFNVVHGDAWCTLCQKVRKHNLKRKLGKKHVPQSYDQLNEWWFNYEYHAEHKSACRKSRWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW10</accession>
    <name>A0A1D2MW10_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000458">
        <property type="protein sequence ID" value="ODM97260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW10"/>
    <dbReference type="OrthoDB" id="10507779at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM97260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="59" mass="6811" checksum="AAE31B14D14ACA5E" modified="2016-11-30" version="1">MTRVAVRELTDSNVPSDVKNEAEKLITVLRNTVMLHPGLVRKRPKNVKTPFPMKKRKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW86</accession>
    <name>A0A1D2MW86_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Signal peptidase complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SPCS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000455">
        <property type="protein sequence ID" value="ODM97320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW86"/>
    <dbReference type="STRING" id="48709.A0A1D2MW86"/>
    <dbReference type="OMA" id="FWDDGHG"/>
    <dbReference type="OrthoDB" id="10261524at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007653">
        <property type="entry name" value="SPC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04573">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016089">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="179" mass="20474" checksum="8272AE8991445B26" modified="2016-11-30" version="1">MHSAFTRSHALAAYTVSVLAGLTFACFVTTAFRDYTADTTINTVTVLVRNVPDYSALREKNDMGFMIFDLKADLRPLFNWNVKQLFIYLTAEYETPNNKLNQVVIWDKIIQRGENALLDHKNIRPKYYFWDDGNGLRGNKNVTLTLSWNVIPNAGHLPNVVSTGNHQFSFPDEYTTTKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWP0</accession>
    <name>A0A1D2MWP0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vascular endothelial growth factor receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_09206</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000439">
        <property type="protein sequence ID" value="ODM97470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWP0"/>
    <dbReference type="STRING" id="48709.A0A1D2MWP0"/>
    <dbReference type="OrthoDB" id="6077854at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051130">
        <property type="term" value="P:positive regulation of cellular component organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001512">
        <property type="entry name" value="Receptor tyrosine-protein kinase erbB-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF611">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="489"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM97470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="829" mass="92997" checksum="FF96E7D61EA81A62" modified="2016-11-30" version="1">MIVTVLIWSTYLISKFSCDSNLKIELNTREYWLGEELIVDLTNNSCTNLPQLFKNRIISTKIGSSRCAQLYDELDCTGESIQLSWFSPSLADLSVWNFQNRTESVRFCQDPCVPGGGSFKKEIQSPIQIKLYSEAEWKGNLVSVQVDGCTTLNESLMLPYQLRSIQIPKDECVLAFIKSADDYDETPPVGNGTGDDCIVEKESDNVVAFQDGTPKLNDLGTWSAFHRTKFAIAFSPCSCNQFGSEPSTSSESESPSTISESTLPTTVSPPELEYYIVFYSKINFEGNFIQIPLNFSDCKNLFEGEDGEWEGVAQSMKVSNGSCVEVYKEHFCTDPIHVELTMEVSVPDLSQLFGMGERIRSLKVCNKTTGGEESSESAPRGEGRKFSGSTMWITIACVGAVVASVLTFFLTRIRMRVNRSGREKLSDKEIEEFLVGLGIQLAERKEDEQDENSSNFENNEEESKLSSDLLAQNQPYNYRLEIPRNQLKFDAKGLIGSGEFGNGTLVRPNEESVFVAIKTTKSHSSAQYLRALLKEVKVMMFVGQHLKIVSLVGCCTVNIKLGELFIVLEYCENGSLEKYIKENRDNFVNIVHKGQIRDNTCQQINPSSPKPPHLNYMQVLPELEAPISEAEETSTQSIFDIHQLINWSMDIAEGMEYLTMKKVIHGDLSARNVLLSSNLTAKVSDFGLSRKMYHYSQYTKNGTDPLPWRWLALESLKNLQFSTASDVWSYAVLLWEMFTLGETPYAGVSSLSNNFIINLEQGLRPTFPPFSTSEVYTIMSQCWDEEPKRRPSFAVIISKLKEIQEANGNQNQIAANSSTNGCTAYKSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYH3</accession>
    <name>A0A1D2MYH3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxysterol-binding protein-related protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08589</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000382">
        <property type="protein sequence ID" value="ODM98093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYH3"/>
    <dbReference type="STRING" id="48709.A0A1D2MYH3"/>
    <dbReference type="OMA" id="LNRMINQ"/>
    <dbReference type="OrthoDB" id="48057at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13291">
        <property type="entry name" value="PH_ORP10_ORP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000154">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF141">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="3" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="11"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="275" mass="30134" checksum="B71FECEA953084BA" modified="2016-11-30" version="1">MQAGTGNLKFCQPCEGQLYKYTNVMKGWQYRWFVLNPDKGTFEYYVSDTDKLQMNNRPRGALHLAGAVISPSEEDSHTFVVNSASGDVYKLRAADARERQSWITRLRIVAERHSHALAQTNSPLVSREHGSSTARMVPTNLSILDAFAQVQEWLHKAEISCQEVGISIDRFPISGSGTKSTDPDLLILKATSQTTLGNLQECLYALQMQQRATVKAEMQATSSSSSKHFQSYTSPVAMSSSSTPVTPTSASFTTSHRPSSSVSSSGAKSVHFSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYR5</accession>
    <name>A0A1D2MYR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Myosin heavy chain 95F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08486</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000374">
        <property type="protein sequence ID" value="ODM98193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYR5"/>
    <dbReference type="STRING" id="48709.A0A1D2MYR5"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00117">
        <property type="entry name" value="TFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032412">
        <property type="entry name" value="Myosin-VI_CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46679">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46679:SF1">
        <property type="entry name" value="GLUTAREDOXIN-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16521">
        <property type="entry name" value="Myosin-VI_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="353"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM98193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="754" mass="83733" checksum="68D6CF2D53204C19" modified="2016-11-30" version="1">MSGVDKNGDTGGSEKGQCQTGGKSSFDGGTRDDDVSSSTDSSSILKGEDVATGYTSYFGRPFRIVNPKDFIKEKQAIIAQSAERRIQTENVALKGQLESLLGFPAWKEMVIDQTQQIGTLKSQVQLLATTIEDLKSQQAISRDSQQGQDDSLAVVSVAGDAVPSPPNHNCQEEEEDEIQVLLVLPPPSRPTPPPVTLAHQQQVPVLNTGQADSKNRFSQRVRFKCGKCDRIFYNRENCENHLKSHSTEQLAGCLYCKQAFKDKAAYHRHITSYVMPMLIHSILSAGKRGLSIMASQTGSVSSKSVSKHNLSSWEYTKLREVINTSCDVEFLEACRLELDRRLEANNALDTKYEGGISGGDIHSQVDSSSNNEQDDVTSPSAPPMLPQRYFKVSLPPTKDNLARLWYAHFDGEDISRQLEIEPGREVAVLVAGKDTQNMCGLKLTDTGLTEQESAEISETEFEAEWRKHKRPDTEYQHQEISPQKRFLAILLLVTILLSDFCAVPSEAKGKKVEEVSLITCFKCTDCMSNPNHPVGCRGKQDRCIKLVSDNGMVMRDCATEWGEESDGLSGKNCHAFVDGYKTCYCDTDECNAGSLPHPSFLPITVLTVILIIICIKALRTSEKERISCLLPRIDQSSRINFKSGSVEWVASPVLIKLQRKTWQKSREEWRILSSRIKWLSSPKLRARICFDKLNIKYHAVELNTHPQGNLVQDILLEMTGARTVPRVFINGKCIGGGSDTVALFKSGELQTMAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZK7</accession>
    <name>A0A1D2MZK7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000361">
        <property type="protein sequence ID" value="ODM98381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZK7"/>
    <dbReference type="OMA" id="NICEISH"/>
    <dbReference type="OrthoDB" id="10464004at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="66305" checksum="1D438A37833F0C3A" modified="2016-11-30" version="1">MVISDAAENDISSLDNYQLGQFQPHPLLIDHIVDQIFQNLITSCVNSTHSRQQLCKVRLVCRQWNKAATNLLRKNFQQIFGGLEHNIGQFKKYLQIVHPDTRALWTKLPFTRFTFHSDVFQASTSSSVISFLKICGPELESLVIHKDIYSDAVYEDEMISDVHVPTLKRLAYHDRRRSNISTDATSQKLLFALVTSAKDSLQSLSIQFPREPAYEQQIKQEILIRLLKENGLPNLTCLKLDVLITDEILDTLTGMKLPLKELHFSVGASKFSATSLKKLLETLQYSLQILKITDLFRRSEVTLDFPRLQHLQIFEIHGFELPAYQVSFPNFSYDLVPNLRKLMLRTWAPTLNWEVFFSQSKNTIYSYHQPNILVTELSLAMNFDSVTLMKRIAATFTKLKRLEMYFSRAHVPALEVVFKEMTQLEDLRLNQSYLGEISTTCIDDVLTGLSSEECQWILKHKAFSRTDFHHLESKPGLTNLKNLKRLDIINLRHRNLVTDVTGYMVFLRMPTLRYLAVGHSEVINAVDEMSTKCLWKLAQAYPETMLHEYLNRNRISCKEDGLSKNSVFTSACNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0J9</accession>
    <name>A0A1D2N0J9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000320">
        <property type="protein sequence ID" value="ODM98816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0J9"/>
    <dbReference type="STRING" id="48709.A0A1D2N0J9"/>
    <dbReference type="OMA" id="WIRVFRP"/>
    <dbReference type="OrthoDB" id="7700931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF124">
        <property type="entry name" value="FI05614P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="83"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="34565" checksum="32A47BF2FECAA915" modified="2016-11-30" version="1">MPELLINTVPGSSFFLNLILQRSPFQIQTALRNKKLFFNYISSEGRKTLYVEGGGVNATITQPDVGATNGVIHMIDRILGYADQDIYEKLRTDPMLQMTFRLSSQDDFNHQFKDINRRFTLFAPSNVAWEKIYRIAPSEYKKLTMGSFGYHVSRIIQRHTIVNRVYTIEQLRELSTNASEQAYPIQAVHGLLKVVHKDDVDWKGRDRFYRQYGTSPNNVEGDFSPAFDYTVTWANERAQVVRPNIICTNGIIHIIDTVLMKPDDVTVTYTASSGSMPSVGISSIYVIPSFSLLLIFSNIFTGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0P9</accession>
    <name>A0A1D2N0P9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000337">
        <property type="protein sequence ID" value="ODM98644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0P9"/>
    <dbReference type="STRING" id="48709.A0A1D2N0P9"/>
    <dbReference type="OMA" id="RIMEDQY"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.680">
        <property type="entry name" value="GOLD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF87">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN C34C12.6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="75"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="402" mass="45863" checksum="5894ED4B4ABF6936" modified="2016-11-30" version="1">MGSSKQFTPEESQKIQQLRSACSAILNTEQNEDHYLIRWLRARNMDVEKAEEMLRKSMKWRKDNEVDGILEREEVPIKYRRLFPTGDFGRDSEGDVVIFIPYGRYCHRLVIGVEGMETVLRWHIIWMETMNRLVTNAEKETGKKGLRLVQIVDFDQYSYKELTYSPGREFLIKTNKVADENYPELMKSMVIINAPKVFSLLFGVIKPFMSKETISKISIISGNEETWKKELNSKLNPENVPVRWGGTKKGTDEYCSQIPEVWLGTPVPLSYFTSDYKVHDFQTKKIAAGEKFEVEIPVDISKYPEGTTPNLVWKFKVENHDIGFSITCKALSIGNGDNKSESASSSLSSESVESTVNAESRVDSKEGIQEGNCTIYTSGLYTLLLTTDTAIHAPRQFITLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0S1</accession>
    <name>A0A1D2N0S1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000321">
        <property type="protein sequence ID" value="ODM98811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0S1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="682"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="742" mass="84912" checksum="3F75029201D15299" modified="2016-11-30" version="1">MKPPSYLLTTESPTQTIKIAIEESTQLFLDAVRHATCGSRRISFSRRSHTKAIIVVEDNNEVLELLTAALWFFEKTPLATFQAKYCHNREDFLLTLDACRLYFGTYPAYLARKDERIFERWLGVGMNDVLRSHNSKILLIDFPRPGMLLQRSKDILINRLKMEEKLHNIKSFMVSKPTRKEDNLSTVENLLDEIQKCLEPRDKLLFRKARRMYLDLKLYKQIEQKSRQDVKSLKEWGLPEPENEHDLWERLRNSQIVLNGPIPPLELVCLPDIQETSAISITSLDSNCIENFMSNADAVLSETDTSSLNPNSIAEIHSDEDSATLLDVTVARNLEMETLEDDVEEYSNNDNSRYDAVEEVYEDDYIDYNSMIQNLADRISCTNSIINNDGSSTITSHNRNYQDVELDENLLELESYTHDDSAEAVERIILGSITDLPSFDETIPNEEEQNSNGFHNSCDSLLLEEASSGRTCENFSLSATNVTDNRRNQSLSAASTEEHLNGTLQRSLGFLDLHDDDLLTESVHFTPRYRSHKTSNIMNVTDDELDEEHTAKPYTRIEFTLAPKVTSGESSSRSSISIQKVVKLNKTFDKESLTNSETQIGVNETQSETLQQTKNKPTHKRSLHETCVAHFSKWGKSFTRLLRKRRVFPEAKFQSHHTSRVKVNSSTDGDEKQEDFVEMEMNSSVKSSNVSDNSTVGLMNDTRSNENSTSWLSTVRRYLQLRTGKSSRSGKVFHKLKRCRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N117</accession>
    <name>A0A1D2N117_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000326">
        <property type="protein sequence ID" value="ODM98754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N117"/>
    <dbReference type="STRING" id="48709.A0A1D2N117"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904834" evidence="2">
        <location>
            <begin position="22"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="551" mass="60034" checksum="9487501CC589F634" modified="2016-11-30" version="1">MKRKIAVLITTFLMYIGGTVSLELPPYSLPHHLYGSRELLTVSGNQAGGLFASILHIIHSQHIKGVGAFSTTYAFCGNGDGVSAFLAACTAPETPASQTKVDGAVAVISSLDKQHQIDSVRYMRDSYLYVFAGLLNEELTPVQQLLPVALYEKYIKSPYYIRTRVQNTAESLRVIDVIDGAYVGCSGTPEADGTLNKNCTNLSVPAEALGFLLGKHSNFVNPFYNNGYKHLYLQPLRSFNQTEFTADLTNANLDDVGYYYVPRYCQAYSHSYGHKGSRKGYGSHGYSSHKGYGSESYKHPCKVHVYFHGCGEGREFKGTTFVTHSNYLEIAEKNYIIMLFPQAHSSTDNPTGCWDVFGLSGPTFATKNGPQVLAVWRMIQRLLYLHEDSYTPSSYAPAYTPAASYTPAASYTPASESATPYVNPLTGATYARAGSSSGMKPMGNRMMMMPMTQRNPGLRMQMPAQQMQMSNPGSKMQSSSSSTVNSGSKTQSSNSQMPSSASKTQSSNPQMSGSASKMQNSTSQKSSSTSKMDSSSTNSKGSTSQTKHKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N181</accession>
    <name>A0A1D2N181_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MAPK/MAK/MRK overlapping kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_07711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000306">
        <property type="protein sequence ID" value="ODM98971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N181"/>
    <dbReference type="OrthoDB" id="2158884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="397"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="619"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="675"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="779"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="881"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1008"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1271"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1380"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="592"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="691"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="780"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="890"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1024"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1042"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1084"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1133"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1271"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1288"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1313"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1339"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1394"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1406" mass="161225" checksum="39D7EC197CE26E4B" modified="2016-11-30" version="1" fragment="single">RTLKDKNKDEDKNAVASKSSENIRNDTFHKKRMKSKCEIVVKCFEGTKLLRKLARAPTQSWSHVHEISEIATLRAIQKHTNILQMLEIHYDEKLGKVSLVFELMDVNLYELIKDRKRLLPETRVRTIIFQLFRALRHLHKLGIFHRDIKPENILIKLKTDQLKLGDLGSVRGMFSRPPYTEYISTRWYRSPECLLTAGHYSNKMDIWAAGCVFYEVLTLRPLFPGSSELDQINRINNILGPPPIKLLETFQNKADVERDTFRNQNQKARRQQIQKVLDGYKSKYILQVGESKSNSNKSLRTSKNSLETGPVYFSERTGTGLEKMLPSHITREAREIIKNCLAYDPEQRPSAQRTIQLPYFYELRESYAKNPEKVSSKPVVAICDETVMEYREPIDLGTLGDNKKKRHHRPQHQTVVQEVYRKSKDSSKISPKKGSSKLEVNNNYTSSPNNSIGSLSRISNISRVQGSKTNLTKQQVLQVRKSEDTLPTDSYGKLHNSRHLVNAETSRSSYKVVSSSTGNARSKNNFETEVRKRIHSTSYESIQSEGKQKGKNALEEKSFSTINTVSLNEKVVSTRRLKDSDESLASIDTKMSKDSESCTTASRKDFRRSNNALNNNTVRQSQEKLRKTNASSHKMEHVGQNIKKSVLPSDVSPYMQAPSELKFLQKKIKSNTTKKPTNLVFNHPQQQQQQTVSSQMDKGRVQQNNGKHESTKVSVVPPKVAAAAIKYAKSLNQNNSAAVARQLREVLGDAPTARSGAYSPNESSYAASSVKVGKLRFRQAQHQTTKGRASPDNYQRSKIPVPIDDGEISRKSYKSSKLTSPPQSIREKDITDKWRNTGIPRMIPMSPERERNINLIRESLTMDKNKRLKIRQEAINNSHKNDFEYDPLASQDTSQHQQRVTETYSSGRYLNSTTDYENIECQETSSSAAPAENHIFEQRTMMIKLPELTEEIKKPGLKSSGMYSDLHEGSRYKVASSLAATDVNMNILNDGGGYKKRPDRNEDIKEKLDQKIHTQRHKNSSSVGDRDHTKLARESRNYEYNRYSSGVATNNRPSGSTLPREDEPLRRKRPPVPPTKIHGSRNADMNKEHQRREHSPEPLTMKIGPPYHHAKRANRTSEAVKEYSPKHSKKTRRTAETRKEYKEHGKRRSGRMKSTMRVVRGEEVWCSSDDDIMETMRKKFDDLISERARRLTESLKTHPIPISNEARKACNSRSEDDVSVKRLGIEKPIKYARRQLRARMAESLIANNYPNWRDALPDHLAGQNLHLSHGLIQNNTSNNSGDFVAPSHDTRTMRESEEKYHDKQRQPAVLDLRQSKKDYHDGHNFKNRRGDESRLYSFLQDSNKGQIYTPQGNKPVYQSPPSQVGATLNDRKLRYSHNSLVPVANHSTYTQRRNHNEDDIRNRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N193</accession>
    <name>A0A1D2N193_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N193"/>
    <dbReference type="OrthoDB" id="8288835at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="23107" checksum="2652F8178529B4F4" modified="2016-11-30" version="1">MSFIILGLAFVASELRIMRRNMQILLNTDKTASTLRKLRLIVTHMNQAFRSYLMWFSPILYALVGLLLFGSIRVLHTDFLTNSMFPVCGMRCVFEATTPLAMAGNVSQESEKVLELWREKMVTVTKWVRSRKMIGMVQRASGRILCTAGSLYTFENSICCRKAPYSRDPRSTDSTVSASTLTAICSDPSLLHIKKSASFSTLEGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1E1</accession>
    <name>A0A1D2N1E1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-glucuronosyltransferase 2A3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07551</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000298">
        <property type="protein sequence ID" value="ODM99116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1E1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904858" evidence="4">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="351" mass="39406" checksum="812FF81FAF58976C" modified="2016-11-30" version="1">MRAQKVCFCFSLLLSVFSGISVSGSNILFFHAVATASHKIAIWPLAERLADAGHNVTYIFPVNKKMGSHPKIEELTPSKMVKLMSDFVSDFDINIRLNDKVDEWTATAFSRSIEFCEAFYDSPEIQEWLARPGLDYDLMILDTLSECGYGLVYKFKAKHITFVPVSMTPFLSDGIGIVPESSSIPDVTQKFKPSETSFMNRVRNTLMVLLWRYGYLDFSSNVLPVIESKLNLTDFPPIEEFERNTSLVLVNHHFIEDYPRSFPPMVVPISGLLCNENTHPKIKGFVTQGGRPSSQEALCFAVPLIAIPIFGDQDYNANRLESIGAAIKLDITNMSSTLLKDSIQELIQNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1P3</accession>
    <name>A0A1D2N1P3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_07476</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000294">
        <property type="protein sequence ID" value="ODM99206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1P3"/>
    <dbReference type="STRING" id="48709.A0A1D2N1P3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000016">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="59"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM99206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="23444" checksum="BA5037295594AE01" modified="2016-11-30" version="1">MPKASGKHASSSKGYSVFVLRRLSSIARLQFVTKHMFNTLHNSYEALVGKVVKKAGKAQKNISKGETKKRRHKRKESYAIYIYKVLKQVHPDTGVSSKAMSIMNSFVNDIFERIAAEASRLAHYNKRTTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSSKRNPQQTDQTNALLRATTISKEQNFKISSLLIFYIRHFKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1V9</accession>
    <name>A0A1D2N1V9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000289">
        <property type="protein sequence ID" value="ODM99276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1V9"/>
    <dbReference type="OMA" id="WITKLAF"/>
    <dbReference type="OrthoDB" id="6354542at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="245" mass="26962" checksum="8D266DE89E403D07" modified="2016-11-30" version="1">METLQMSSLLADTVNLLIERLRAEKNTINSIDGKKPEEEDMAADYGGGGGGNGHGAITLDPVSIISLLALGAFLINNILQLLRANMGAAAMPTMPREGGRLMRSQSDVLPFIMPSTLTKNGLPFPGDEPSFIDFFENVGSLYYLQPKKRNMCMKRVVCNYINLKEGRENNPAPLKNKIFDFMLSTVTKLVAPEISDNDKEEKCTRAQKFCSDALLKDARVSIEYKIYSQVSSWITKLAFNGLASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1W6</accession>
    <name>A0A1D2N1W6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2207 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1W6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904897" description="DUF2207 domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33888" checksum="77573FFCAB824EB4" modified="2016-11-30" version="1">MRLANFVTIICIVFILSFMGLTAEAQGTCGLANIDEGSSNDRYVISLVSDYLVNRTLIWQHRFFGQVSKTSATDNPDFRYVDATHTTSYYRMYSNSRTRFYPRDMNKREITRDVLIECKDGTSSRYYLKVPLQDMTPPEFSQAVYTLSIKSGWNIQRPISEGQFIIVNDNDYELGKENSSKMLNFHVSVDNLLNITWTKLWIAPNPEKYYYRLDMFLQEDSTRLPLGKNEVMLSALDDFNAGFTKIEIIAAVVLALLVIVAAVSAGVYGPVGPVVGYAPGGPIGRTFHGAPLINGYYGGLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-05-29" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Y1</accession>
    <name>A0A1D2N1Y1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07377</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the eukaryotic ribosomal protein eS32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000288">
        <property type="protein sequence ID" value="ODM99306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Y1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007836">
        <property type="entry name" value="Ribosomal_eS32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05162">
        <property type="entry name" value="Ribosomal_L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="116" mass="13425" checksum="55B38951B4D5ED16" modified="2016-11-30" version="1" fragment="single">LDILRDNCKPRADSHLSPNSILLNDPCPHTTNGSMNRIKKNAVWDRSENVQRERSVSAHSAYTLCGHHAVELRASGNLSTLKGFPLPLLSVMRAKWRKKRMRRLKRKRRKMRARSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N201</accession>
    <name>A0A1D2N201_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">La-related protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000288">
        <property type="protein sequence ID" value="ODM99313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N201"/>
    <dbReference type="STRING" id="48709.A0A1D2N201"/>
    <dbReference type="OrthoDB" id="435402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024642">
        <property type="entry name" value="SUZ-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12901">
        <property type="entry name" value="SUZ-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51938">
        <property type="entry name" value="SUZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="396"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ-C" evidence="5">
        <location>
            <begin position="696"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="344"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="491"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="512"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="539"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="758" mass="82190" checksum="823A1568AE8A12A3" modified="2016-11-30" version="1">MTNTSEEVSANCPRSKSEEEAAVITTMMPRGASYEAPSMHCNTFCDDDDTIAREANELFVTAAAGNAAKAARRVGFGLRRTNNNLHDKDITKAESMVRDTTNIHNDFDDTTTASSSDDDDDDGLFNEEEDGAYKTCSSATLSQSVHILQPEEQPKALIATFGLFLVQAWNWLHYLFVTIIFLNYFDAEKPNFADKSRKNDEVVHNFCGGGSVQGGETETEFTSDNTTVVEESSSLTSPVGNMSPNTCSIQNQEESVEKAEEAIIMAATTTTITAIAAQEKVEVTAAGVQEQQQQLSAPQIQIILSEVPEKTPELDENLDDDDVDEGVEEGEEVVEMGVALARRDSVDSYTSSEGSGNLGDAEEDNVSCDKSSTSTEENDNSNSNNMMISSSNDNNDDSGKPLSQKIVSQVEAMFSDEHLAKDGFLLKHVRRRSDGFVSLKLVAGLRKVKQISRDFPQVLIALRDSTKLEINAEGTKIRRAEPLTAFLKAVPIKAKEKGPGKDKENGSSNDENQQPPTTNHQQNNKSPSRSGKENLDNARSVNNNQNGNNNNNRRNSTQNQSNVNNNGGSQSRRKQQRLSPDHRKSSNTSTASSNNSRPTQQLQQASTFLSSHPADLLRNVYSSVVAYSSSGEESQSPQVGRRRGGSLPITALQRTSGAAYLSPNSSPPGNGAFITIGPNGARPKSNSYCEGTSPTTMSPWLLKRKASASSRLSNGELTFSGVVRQPRGPDGTKGFASGYRAMILEERLQQQTNSAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2S5</accession>
    <name>A0A1D2N2S5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000286">
        <property type="protein sequence ID" value="ODM99354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2S5"/>
    <dbReference type="OMA" id="VEPIVYE"/>
    <dbReference type="OrthoDB" id="10492545at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904939" evidence="1">
        <location>
            <begin position="23"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="14248" checksum="147C47B82A35E524" modified="2016-11-30" version="1">MKLALANTLGVLMTILVIKTEAGILPVQQLLYGYPSTGSQQTTVIRDALGNQGTGYAYQTSNGISSSAVAVSRSDNSKTLAYLPAAFAAAPVVATQPLYAHHQLHHHHHLQPAISVASGGYHVPGVAYSDYNTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N413</accession>
    <name>A0A1D2N413_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_06708</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000242">
        <property type="protein sequence ID" value="ODM99970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N413"/>
    <dbReference type="STRING" id="48709.A0A1D2N413"/>
    <dbReference type="OMA" id="SHIYFVM"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000465">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="28"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM99970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="354" mass="41021" checksum="847A6AC558853BCF" modified="2016-11-30" version="1">MIDISMKLIISHDAPISILQPTGKLDDYIICKKLGSGQFGKVYLVQDFMDRKHYALKMISKDVILRNHLKKDVESERDYLYSTNSPFIVSLIHHFEDAKAVFFVEEYLSNGDIYEHLKQNGPFSEELTKFYSSQVVLALEYLHNVNLIYRDLKPENVMIDSHGFIKLVDFGFVKRVKREDNYKTSTMVGTPSYMAPELILHKSYDKNIDWWALGILVYEMLAGIQNTPFADANRMVMYEKITSKEVTFSNKFPHTTVRDLIKRLLKVNPTLRLGSGPNGSKDVKNHPWWVSLKWNDIYRRNIAPPTKSKNLFNKANNYRGPKNTKLSGMGVTSSRPVDINLLRLENKIRMELNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5H2</accession>
    <name>A0A1D2N5H2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">DE-cadherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_06155</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Cadherins are calcium-dependent cell adhesion proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000201">
        <property type="protein sequence ID" value="ODN00523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N5H2"/>
    <dbReference type="OMA" id="EQPENTY"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034332">
        <property type="term" value="P:adherens junction organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016339">
        <property type="term" value="P:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044331">
        <property type="term" value="P:cell-cell adhesion mediated by cadherin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007043">
        <property type="term" value="P:cell-cell junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001736">
        <property type="term" value="P:establishment of planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000021">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000058">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.900.10:FF:000012">
        <property type="entry name" value="Putative DE-cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.900.10">
        <property type="entry name" value="TCF3-CBD (Catenin binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000233">
        <property type="entry name" value="Cadherin_Y-type_LIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027397">
        <property type="entry name" value="Catenin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056370">
        <property type="entry name" value="Shg-like_Ig-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF422">
        <property type="entry name" value="CADHERIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01049">
        <property type="entry name" value="CADH_Y-type_LIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24811">
        <property type="entry name" value="Ig_Shg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="13" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 11" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 13 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1435"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="19">
        <location>
            <begin position="85"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="19">
        <location>
            <begin position="188"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="19">
        <location>
            <begin position="323"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="19">
        <location>
            <begin position="415"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="19">
        <location>
            <begin position="547"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="19">
        <location>
            <begin position="675"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="19">
        <location>
            <begin position="786"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="1160"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="17">
        <location>
            <begin position="1200"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1524"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1605"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="1170"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="1189"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1392"/>
            <end position="1419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN00523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1624" mass="181724" checksum="EC156E472A7B7E83" modified="2016-11-30" version="1">MREIHKHRQHHGHDHPRSRTRRFGRETDAPLVQNYQSYLSESRVTEPYAPYSYRQDLDESPSRFSSDQNLHKPEFLNCSKDITPSVPEGEPVNTTVFRVEARDIDPPEFGGTVTYSIVSGNENNDKFAIDPRTGVIRTNKVFDRDEPEREKEEYLTIRATDNGRPQLDTVCTIKIIITDINDGVPLFERFEYKESVPRDLSTGQVVMRISATDIDDRENGTVWYKLDSHPESPGDLDYFKISETTGEVQLKKPIDANTHQFLLRAIASDKGSPPKSATTNLTINVIEPRTRPPSFDPHRDIIYLRERGVDKTRPIETLTAKANADSNLVFFELVNGQTEPTNKGAMFTIEADGNTAQLKLDKDLDYEAVSKYTLTIRVKNKDDLATETTITIFVEDDNDEKVKDLKHLRKFDPDFTEVTSGVVLEDENVGTSVMRVRAIDRDGTSPNRDSHITLVSLPRTDFTQVLTLQVTYALKEEDRENFEIDPITGEITTTKKFDREVKDVYQVTVIARDGYPSALRSDGLPNERPITLKIEIADKNDNSPVFLKSIYEAEISEDADANNRVIEVKAIDKDTGNASQNDQFTIDFSFAYYPASEIKYSITQGNIGDAFSIINAKSGGVIYVSKKLDYEEIKDYDLTVQASDSIHETYTHVKIRVININDEPPKFEGMKDNTTILEESIPSNCVFQLKAYDPDIGDRSVPQNISYFILQGKENFNVDDNGCVKVTKPLDRDHGDHIRTVIVGAYDEGGLTATKLAAYQSLKVYLEDINDNAPFLNSTNPVVWDENQPKGPITKLYADDFDDPTKNGPPFHFSIDRAAPPEIRTLFRIDGNSLSAEKDNFDREEKKEYLVPITISDSGKEPQTGTSTLTVIIGDENDSKMFPGESKIFVYKYKEKSPFPIGRVYVEDEDDWDLPDKTFDWQNGIPHTFFNLDHADGYINMKPTATAGTYQLSFKVTDNKHNQEVNANVNVTVKEITDEAIESSGSIRFAGITKEGFIKPDSTGKSKKDLLQDELAARFGVPKENVDIFTVLNPLQSPDPYQIDVRYSVHNSPYWKAEKLDGILAGAKETVSWFCLLLSYACFASWNPDSAFANLQKSLQLQILMIRIDECAIEKSPCEFSCTNHLNKSEISYKIFTNTTSFVGVDAYVTASCTCSSAVQQNGCLPNNPCLHGGTCKSGGGKDGFECECEAGYDGPRCEKTSIALQGNSYAWYQPLSVCNDSSLELQFTTGYKDGLIFYNGPIFPSPMNVTGNNHFVSLCIALENGVHELYIKFYTRVDFVSLELRDGKPLLLMDYGTGVAKVELVNSPNLGNSLPHQVSIKWNPKGISMRIDDCLKNEPACFSDNIPPIGNNSQLNVNGPLQIGGISFNPASLQSYNHWSSIPSSKKFTGCIANVTFNGMFYNLGAPSYAYNMNVTDCDNPLIAGSFKTLSVDWNFIIVILVSILVLLLLIMAFLFYRKRRSYEEVKGEFNDDVRDNILHYSDEGGGEGDQTGYDLSVLMKASNGPPYINPHMDKIAMDDLNRQGRAPESGEGPDIQSFLTGNKNKVDNDPDGLPYDDVRNYAYEGDGNSMGSLSSLASGTDDEDLNFDFLPAFGPRFKKLADMYGGQSSDDESYTPPPEAWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6D0</accession>
    <name>A0A1D2N6D0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000186">
        <property type="protein sequence ID" value="ODN00791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6D0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="24641" checksum="2D6C59C5260EE331" modified="2016-11-30" version="1">MNTYKTEPILLVPSLVDEDCKRFCFESCRLYDQVLRNVCIAVQQECDCIRRKIAYRNTQLHPFLSKAPSQESCKKYCKEGSCQKYFKLDSSTFSECVGAITLCSCSSTIVRFHPELTSVKVAGRLVSETTYSTRFLIGAIAILVVCLILATLVGVYLWKNNNGRRIGVLEQRLQPDCNVENGNGQFQTNTHEDIGIGTDQISPSRHTKMFDVSLIELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7A2</accession>
    <name>A0A1D2N7A2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Actin-binding LIM protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05537</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000169">
        <property type="protein sequence ID" value="ODN01148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7A2"/>
    <dbReference type="STRING" id="48709.A0A1D2N7A2"/>
    <dbReference type="OMA" id="CKKKCVG"/>
    <dbReference type="OrthoDB" id="1746725at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030032">
        <property type="term" value="P:lamellipodium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09327">
        <property type="entry name" value="LIM1_abLIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09329">
        <property type="entry name" value="LIM3_abLIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09330">
        <property type="entry name" value="LIM4_abLIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000055">
        <property type="entry name" value="Actin binding LIM protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000075">
        <property type="entry name" value="Actin-binding lim protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.950.10">
        <property type="entry name" value="Villin headpiece domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032402">
        <property type="entry name" value="AbLIM_anchor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051618">
        <property type="entry name" value="Actin-binding_LIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003128">
        <property type="entry name" value="Villin_headpiece"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036886">
        <property type="entry name" value="Villin_headpiece_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24213">
        <property type="entry name" value="ACTIN-BINDING LIM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24213:SF9">
        <property type="entry name" value="UNCOORDINATED 115A, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16182">
        <property type="entry name" value="AbLIM_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02209">
        <property type="entry name" value="VHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00153">
        <property type="entry name" value="VHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47050">
        <property type="entry name" value="VHP, Villin headpiece domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51089">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0440">LIM domain</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="10">
        <location>
            <begin position="31"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="10">
        <location>
            <begin position="139"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="HP" evidence="11">
        <location>
            <begin position="708"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="445"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="543"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="773" mass="87341" checksum="DB6CA03FF2CB7E59" modified="2016-11-30" version="1">MSLAYSLTRFTMFCKMDQICSIFEDEDYGKTVCQACKKKCSGEVLRVQDKYFHIACFKCKVCGSSLAQGGFFLHEGDYYCTSDYQQRWGTQCGACGRYVEGEVVTALGNTYHQACFTCARCRKPFPTGAKVTVAGREVVSCAGCGLELRDAQALVALDKQWHIWCFKCKACETILHGEYMGKDGVPYCEKDYQKNFGVRCAYCYRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYLQGTAIWHPRCGPGPNENGTVLNGLVENGHPIVEDRPDSKLDHSCSVSETQFSLRSRTPSLNGSLYSPFNSLSRKYSGYRTSSPGLILREYKSPYGDDITRIYTYSYLTAEPTHGYLKKPIDPYDKPPTSPHFHRPPSNYTLLSKDKHFTKHSIKNLGNCSRTKLQLSKQGSKSGMKAMVENLVCETPRPKSPHMNNEEPIELAHFPGAKPPKPDEKPKIERDDFPAPPYPYTDPERRKRWSDSWKGVSASEDEDEADSVFKPEDDPKLKKEEEELSKIATGIGKVFLQNVKEREKLRAWKMSHLDPRNASRTPSAAKEPALKLRYDSPHNASPSRNLDHPRPWEEDEIDRCSSYRSSVGRSVGTIPAYNVVSSLRQAPKPGYTLAPRSHTFSSADYPFGAMGEKTHSTEFSSARSDISTGSITEADRRALGADIRSSTTYTGGFRYPSASPHLRRSLPNMTPVMSTEPLKVYPYHLLMTSNYRLPADVDRNNLERHLSDAEFDAIFHMSRVEFYRCPGWRRNDMKRRARLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7D8</accession>
    <name>A0A1D2N7D8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Neuroligin-4, X-linked</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000168">
        <property type="protein sequence ID" value="ODN01179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7D8"/>
    <dbReference type="STRING" id="48709.A0A1D2N7D8"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="20725" checksum="9AC8D19F8EC24867" modified="2016-11-30" version="1" fragment="single">MKRERVVLVTFNYRLGVLGFLSSGNEDLPGNYGLLDQIAALKWVNKYIHRFGGNPLRVTIFGSVEYLLLANLNDEKNALFHGAILKPQSTSVLSPFAKVESREGAKNFMRQIADNVGCKQVEQEESDSTHALVDCLRRADTDSLIRSQMKAMTFHNFPFRETHSSLGPVVDHKLLEDEPEVLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7Z7</accession>
    <name>A0A1D2N7Z7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein phosphatase 4 regulatory subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000154">
        <property type="protein sequence ID" value="ODN01400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7Z7"/>
    <dbReference type="STRING" id="48709.A0A1D2N7Z7"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039918">
        <property type="entry name" value="PPP4R4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21467">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21467:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="22496" checksum="1C87ABDD5E470FE9" modified="2016-11-30" version="1">MSITVIGFAQGRSVHDRMLFLYMAKKIMERFSRMYFRDHFFEDVLVLANDPIINVRRKVMELMPELKGVTEDPALQQKVDAILHKSRRSEVDRDMKGVIEELLSKMNGKKDKDSKRSTKAAAAEPKPKDPDDEKKELEEAFIESLEIDVGKAVSKTTVKEKRKSFFGSTKRKSVTNEDGNGNLPSLPMFQKAAAASNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8D7</accession>
    <name>A0A1D2N8D7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein flp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000147">
        <property type="protein sequence ID" value="ODN01540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8D7"/>
    <dbReference type="STRING" id="48709.A0A1D2N8D7"/>
    <dbReference type="OMA" id="MAGHIMA"/>
    <dbReference type="OrthoDB" id="7773096at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905201" evidence="1">
        <location>
            <begin position="24"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="64"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="562" mass="63216" checksum="685D00973A746B02" modified="2016-11-30" version="1" fragment="single">MHLLKSVLVVLFSVSHFPRDIKGLTRSIDQEIKKEIDDFIKDVYLPSNNITGLGLTVLQLQNGEKEEVLYTAGFGLADKAKEIPNTNETQFLIGSITKSFTATIAVKFLHETFPDLGEKVLDTPVRELVPEYNFTLSDRFRSEQVSFRDLLAHRVCSNRNDFLLLSEATNSTSELVYRQRYNQEMCPIRSEFQYSNNMYAAAGELLAAIAKKPYETLVSEFLTELGMSNSSLVQPSDDFSSMPFRAQPYYVINNVSYPSNEGLVKRVTTTNSAGGLCIPPNDMDKYLRFHLNEGQIGNSQIIPKDVMLWLTKSSISVPLFGYKSSEDDVEVINTFAYGLGFFLASLDGWQLTEHSGSVPPYTAQLSLFPKQKIGIFMGMHEGPLWVSPMVVHGFIFDILRGVNSTTATEKALKLIEKARQKQESKVKQEKVALFRKPAQEKRNWAEIVGKYGSGSSGDLEIIEKLNDQTNATQLYLNAGKWYRGWLGDEDAEGRFLLTWDSDVNQDYYAAGDLSGGEAYVQVRNGTAELLHRIVDELGSLAKFELGNKFSRDKVWKLKDVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8Y0</accession>
    <name>A0A1D2N8Y0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Activating signal cointegrator 1 complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000147">
        <property type="protein sequence ID" value="ODN01545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8Y0"/>
    <dbReference type="STRING" id="48709.A0A1D2N8Y0"/>
    <dbReference type="OMA" id="NAISACF"/>
    <dbReference type="OrthoDB" id="5577209at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14364">
        <property type="entry name" value="CUE_ASCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052586">
        <property type="entry name" value="ASCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041800">
        <property type="entry name" value="ASCC2_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494:SF0">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="152"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="458" mass="52521" checksum="A7EE4FE24F82EF35" modified="2016-11-30" version="1" fragment="single">LAATYEPQCCKLWSKASYHLPSLEERVMVLRMLIIRLYRVTLVSATLQQVSSSNDQRIDEFFEVLTNCLDEKTFIRDYEKAYPFKQDINDLLSRGVFIDETRIDYMANAISACFHACGEDYAVEKIVVDPLYDPNFDRQLLGACSLDITGVELQSLVTQVKDILPELPDSYVEVVLKHYGYQSEVAINALLEGSVPTRLEKYKNESYVQPLNDDQVGSTDRGVGTDNALEKLASRLKIGDVWKQQDAERFYAGKRRHGFESAPSNEMAEDMKLKIKDICSMKEEPTKPTKDVKSGKKSVQIQTPNTENSKDEPYVDESLLPTFHRSLEYEYEDEYDDTYDELGVGMTEPDNYKPLNQKLSRAVEQDDDDEEESQEGKKLDLYEDPAIVRARLERRREDKMQHHQRRGPGPPPQAADVVGKAKGQGQDKDVLYARRQKTANKDSGGYKKKRADFKRREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N944</accession>
    <name>A0A1D2N944_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein atonal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05174</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000149">
        <property type="protein sequence ID" value="ODN01506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N944"/>
    <dbReference type="STRING" id="48709.A0A1D2N944"/>
    <dbReference type="OrthoDB" id="6161578at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070888">
        <property type="term" value="F:E-box binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061564">
        <property type="term" value="P:axon development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016360">
        <property type="term" value="P:sensory organ precursor cell fate determination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19715">
        <property type="entry name" value="bHLH_TS_amos_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000025">
        <property type="entry name" value="protein atonal homolog 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050359">
        <property type="entry name" value="bHLH_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290:SF162">
        <property type="entry name" value="TRANSCRIPTION FACTOR ATOH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0221">Differentiation</keyword>
    <keyword evidence="4" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="9">
        <location>
            <begin position="130"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="192" mass="21699" checksum="F6CB5697D0F115AE" modified="2016-11-30" version="1">MSVHQNGYPQDGYSSYNSYYYYGHPPPPHHPPPHGPIYDESYVNTNYWAEEDESYSSSCQSGSPGEPTPTPSTCSSKDLYEDSQRNSLTQNLDIKPSLRPSQNTSMPLRKKGVGGRRKNEKPPTPVVLKKRRLAANARERRRMNGLNDAFDRLREVIPSLGSDHKLSKYETLQMAQTYINALRELAGAPKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9F6</accession>
    <name>A0A1D2N9F6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000145">
        <property type="protein sequence ID" value="ODN01626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9F6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="10834" checksum="CDD816E69E534DDC" modified="2016-11-30" version="1">MISRDQAFLAIRYYLLSFYHCFGLIGVHVGYHCGYTINHVCACFLLLITGIFFLISVLKYWNDNGKLGVRIMAMIIGFANSAVYGYLPWKLLKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA43</accession>
    <name>A0A1D2NA43_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CD63 antigen</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_04552</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000124">
        <property type="protein sequence ID" value="ODN02121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA43"/>
    <dbReference type="STRING" id="48709.A0A1D2NA43"/>
    <dbReference type="OMA" id="MYANGES"/>
    <dbReference type="OrthoDB" id="438211at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43419" checksum="D42644308FC51139" modified="2016-11-30" version="1">MTTVEVQIGMIKSSSFVASETLVRHKGRSPGSQQINSNCIVCDEQIQIVQVSAQNYQHQPDGSLEQCPCVTVIDDRKFYGKKLSWNDSIVVENNKSARVFSSSLIVSSIVLFLFSFCLLFLMVNNFSGHFLRTKGVILNVSLAHCIFVHATCGLTAGILVRFIFSRRKPSFNCQIWIIVYSGIVLLLGVVSWIYHLMIMIKFSDRLEDFMVEEMYANGESSVYWTNSQNFHECCGITSFRSWNGVPKTSPETKNVYPSSCCDKATYGNRCKSPPTMTEVYSRGCLKHEVNTFMLIGYLSFILSSVHLHFEFFSLLSIVKVYGRQKFVFDHTECCRLLQGSEVNGSVKQATGSQPTSKGQDVEKDPNANVIPIESIVSIELRRAMTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAB4</accession>
    <name>A0A1D2NAB4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000121">
        <property type="protein sequence ID" value="ODN02191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAB4"/>
    <dbReference type="STRING" id="48709.A0A1D2NAB4"/>
    <dbReference type="OrthoDB" id="70770at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17301">
        <property type="entry name" value="PIPKc_PIP5KI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.800.10:FF:000001">
        <property type="entry name" value="phosphatidylinositol 4-phosphate 5-kinase type-1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF101">
        <property type="entry name" value="LP03320P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="5">
        <location>
            <begin position="117"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="556"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="571"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="598"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="799" mass="87826" checksum="15054E9EFD3CAEA0" modified="2016-11-30" version="1">MATANDVHISTRGSGANVGNNSTVELGTDEEGNVITGSSGGVKFKVGGATSTGRPVPPLEMPQPSTGASNTASQTPKTPTPGPSGSTGISRTKSEREKKIGHRRVTQGGDVTYKKIQSSQIMGSIQLGMQHAIGGLASKPERDLLMQDFMTVEQTYFPSGGSNLTPAHHFTDFRFKTYAPIAFRYFRDLFGIQPDDFLISMCSVPLRELSNPGASGSIFYLSHDDEFIIKTVQHKECEFLQKLLPGYYMNLNQNPRTLLPKFFGLFNYICNAKNVRLAVMNNLLPSSIKMHQKYDLKGSTYKRKANKTEREKKSPTYKDLDFVEHHPEGLMLEADTCAALIKTLQRDTRVLESFKIMDYSLLVGIHNLDIAAKEKVDPKYRKTNLSVDSDGEDHDDGGCVAGPSGTGLSRSRSINRQKLVAHSTALESIQAESEPIDTDDDVPPGGIPARNAKGERLLLFLGVIDILQSYRLKKKLEHTFKAMIHDGDTVSVHRPGFYAERFMNFMTKNVFKKIPSLDLPEIKGNHRKFRNLVSTYIVQLLTLVFLRAALKHSPSKKRSGISANLPMSPPASSAQASVQQQLQQAQQSQEADKKATHIDSSANQDNNTVDVSSVHVGGLKTEESETKPEPKPQPPPPQQQQSYPSILMSHRTPGGQTQRNAVAPLAYPPISTPPPQYESSTSIIPIANHTIDEVYSSDDVTVSSSNTITHLSYNRQTIQTIQSNSVNDETVTATSATTSTSSIVNSKTEQLTSHINNNLNENYDGSLDSDQDQNHVTEVKSKPKLLDTLKNDETESLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAB5</accession>
    <name>A0A1D2NAB5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04454</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAB5"/>
    <dbReference type="STRING" id="48709.A0A1D2NAB5"/>
    <dbReference type="OMA" id="SAMMAYY"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF2">
        <property type="entry name" value="FMRFAMIDE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="89"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="399" mass="45480" checksum="7E1A9FC7DB93078D" modified="2016-11-30" version="1" fragment="single">PSAVVYHKMGENKTFRLPILFCALIDFPKNKIDCTSSIPDSGEVVCFKCPIVGKYFFGEQIEDFRSVGHIVCLLLWLLVLIVGTFGTITNSLIISIMRKHTEKRTFDFLLMVLASFDLLSSIMGVISVSAMMAYYEDWDRGPVTLFLFIYPFLLGLLGRSGSSYITVLITIERYLIIAHPLKSVQWFTATKTKLMTFGVSLLALLINIPRLTSVTISKNNEWKSVPSFDAKEYIVEATKLEEFWYLNLKSIHYQIDMWVPFPLLILFNVLLFLRIKQFTKNRQGLSKTQRRDIRAARMFVPVVVVLFLCNIVPITFYIIMHFDRVLYREVVVLLVLSYAVNAAANLPIYYARGPSFRQEIKSALPARCGWLKNGDSTNGEISMTERNTNAAGSNSNHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAY8</accession>
    <name>A0A1D2NAY8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein sprint</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAY8"/>
    <dbReference type="STRING" id="48709.A0A1D2NAY8"/>
    <dbReference type="OrthoDB" id="21085at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01776">
        <property type="entry name" value="RA_Rin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23268">
        <property type="entry name" value="RIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="630"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="855" mass="95246" checksum="AC9EE52F691C5FA6" modified="2016-11-30" version="1">MIVTKTIYDDKASDYEDIWSPHERAHTPRLSTFKPDLIASSLASDLDTCTNILRNKNNNKGQLQSPRTAQSEDEERLVENKNAQNNRHSLNGQHLSQVQIQITDAKDVGLKRRSRIEGEELENRDSVEVENKKSPGLYSEPVDSIAFRRFGNHRHSEPNIRWSQPVLSLVKLDFGGGGGLSEDENRVETVGTGKSKIALLQRRLQEKREQQITTKSYHQSISTSQHQISNNRKSVTNVAASVSVGSELIVNSATMDENTWNINSKSQTCGSVDNLYNSNIQQLLISNPVGTENKKGISVPKEGTIELESDLLILIGFLAPEDLRNSNLQHTSEASVLEVSHNQSWRVDNSWEFVMWQKDGERHPQESTAKFPVLTPPNSPHNVEGGVDHHSGDNFSGISQTESSLNSVNNNQSDYDGSNNNLHRFSRYDNLEIQRAEDESSEDGHLEAEGQEKISAPWDSSKWEHLLRLVSESTQQLDSLQMLESSLEKRRNLNETQASQLVVPNANATESKQRISKILEVSGNVDKASKTIIGAVRQMASKDDGVFGPTLKNTEKVMRNVRQFISGMKNFLVGVSPETTDLRAEIKKQTEMLNDSEFLNIDSILEEVLGDLVIAPLNLHIRGLIDSYIVKTQEPLTLKNQGATEFKYFTLDSQSKAGFEKLKNIYSGFEDSVSPIRKLDKWNEYVCQVQDMENYSSDSFLPLLTEMLGATASVSLPSHVEYMIGLLPHSLAEQNNYSLSLLQSAVSGVKCQNDGSHGTSTITSVRVIVPDERNGTLIRKVVPVRQSTTNKEVAKMVASKLGITNPGDYVLVKIKDGEEKLCVECDLVSESVGDTSAALAYKRIDAKIGWPQRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB08</accession>
    <name>A0A1D2NB08_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arp2/3 complex 34 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04238</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
            <location evidence="1 8">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ARPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB08"/>
    <dbReference type="STRING" id="48709.A0A1D2NB08"/>
    <dbReference type="OMA" id="FRSYFHY"/>
    <dbReference type="OrthoDB" id="148331at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000002">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000004">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007188">
        <property type="entry name" value="ARPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058">
        <property type="entry name" value="ARP2/3 COMPLEX 34 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04045">
        <property type="entry name" value="P34-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00065815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="302" mass="34979" checksum="33F7F7CA1300C4AB" modified="2016-11-30" version="1">MILLEINNRILEDTLALKFKNALSGGKAESTDITIADFDGVLFHISSHNGDKTKLKVSISLKFYKELQEHGADDLLKREYGTFLLYPSEEGYSVSLLFDLEAVPNDWEDVVKKVGLLKRNCFASVFEKYFEFQTKGIEGQSRAVIHYREDETMYVEAQSDRVTVVFSTVFRDEDDVVLGKVFMQEFREGRRASHTAPQVLFSHREPPLELQNTGAKIGDNIGYITFVLFPRHTNPDSRDNTINLIHMFRDYLHYHLKCSKAYIHSRMRAKTSEFLKVLNRARPEPRNVEKKTITGRTFIRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBK7</accession>
    <name>A0A1D2NBK7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein tramtrack, alpha isoform</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000102">
        <property type="protein sequence ID" value="ODN02643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBK7"/>
    <dbReference type="OMA" id="MEYLMIG"/>
    <dbReference type="OrthoDB" id="6418787at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="47"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="619" mass="68643" checksum="442443671389C8BA" modified="2016-11-30" version="1">MSSDSTNQEGQESTEKRAVTQVCFVNEDAKVSPSAVLQYVLDVDQPYDTVISCADGKVGAHRLVLTAASAYIGEMFCKYNHRLGEVAVLVLPDVPVRIMKILLTFCYTGKMIYPKEDELEVLDTMKLLLLGEYADLEINEVTIKAELPPEPVPSTSTSAEQMGQGLQTGTDSVMPPPILNNQLGLEKPPEEVEDDCITTTDEESDDADSNYEKENKGKRSKSSNCKANDSGVATDQTNKASPHHYLIVPQVGGGRSRKLQCSHCVGAFKTIENLSSHLEDHHDIILEPHKLKQKEFEVLSFCNHCKKKHDQISSANSCLSKHNRTRCYVCFQTVRHSQFEQHMKSLHPSLLKNGKYAVKCNWCDAGIVFGDHFDNKTMAGHCFRHHFPGSRGNASIEIERPENSSTSKAKISPSTSTEQKRLPIPKSEPMSVPSKSTATSQLKNSTPITSTTPSTTRQSSGRPVPAVLALLQKASLKRKSVQDSPSDVRVKIENPEKRARVDTNIVKAKMQNQVAKRTGIPVGRLVNLNLMKDGVPDFKCPKTRAKSKSVTIDVGNLPKVYVQFNYGKSFIYDLYNTTTTQETTAKPCKKDLPETTTPGTSFKAGDVRERWFRCSMPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBW7</accession>
    <name>A0A1D2NBW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Another transcription unit protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000097">
        <property type="protein sequence ID" value="ODN02742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBW7"/>
    <dbReference type="STRING" id="48709.A0A1D2NBW7"/>
    <dbReference type="OMA" id="TIRWREY"/>
    <dbReference type="OrthoDB" id="20844at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007149">
        <property type="entry name" value="Leo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146">
        <property type="entry name" value="LEO1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146:SF0">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN LEO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04004">
        <property type="entry name" value="Leo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="746"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="790" mass="86170" checksum="A17D468ACC4C3342" modified="2016-11-30" version="1">MLHNMPQRKMRNQSGSDDDDSGSGSGSDSGSDSSGGGSERHSSRASSPQGTPPRSRSPTASPKSPMDVDSPKSPKSPEAPVSPRSPPGSPKSPAASHTSRSRSATPIGSAKSGSRSRSGSPASKSSGSRSGSESRSRSRSKSSERSATPAASPKSGSGSPVAKRPRSRSASHSPVRSRSRSVTPPAKSKSRSRSRSGSPSSRSSSAASNASSRSAASRKSRGSASPKSVVAKSTVSRASAGSGGESPDQSVVSEIQKSKPGASDIFGDADDISSSSSDSDEDKKSDDEKEKSEPVVEAKAEKMDVDDASDAEAATEKPPTVEADADVDMDENKSDAGSKAGSKAGSDVEPEQEQEVEEPLPETRIDVEIPKITTDLGKAVHFVKLPNFLSVEPRPFDPNTYEDEIDDEETLDEEGRARLKLKVENTIRWRERFNDKGEFVKESNARFVRWSDGSLSLHLGGEIFNVYKQPLQGDHNHLFIRQGTGLQGQAVFRTKLTFRPHSTESFTHRKMTLSLADRSLKTQGIKVLSQVGANPEARREEMIKKEEDKLRASLRRESKQRRVRERVTGRGGGLSSGYLENDVDDDDDENVISLSAIKNRYKKGNNAGQKSRSHIYSSDEDEEENEGSDIEDRLKSRKLEKAKALKMSDDEDDEAGAGPSTSRHPAGDDHSDDGRIVSKGSSAKRELSGMLWGNIQDPSFLAIHFHNTATPDLVRQKVTDRTMKFPYTLTAQIRQFPYRFYWQNQWIFRYWVISTGICLPIFYWIQTKARSPENIKKWKESKAKEAAEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBW8</accession>
    <name>A0A1D2NBW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBW8"/>
    <dbReference type="OrthoDB" id="524165at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="587" mass="66513" checksum="5D74965B39620035" modified="2016-11-30" version="1">MFPYGKKKIRVFPFRPTPDRGSFIDFIEETGTNAFLIEAVKKLYELPNKPENPIEWLRLHFKYLAPDRTKEMQETEELLKIELSEILINAHEEEAQNLEILTKLENEYKNITMASGKIYHYEDFRKYLHHPDDYHHRIKPDPLYQASKSDMLLPDEDRDSNLIIELVPFNTTKFSADASNRKVSDQHIYADYPSTYFPEKLRGPISPGGDEETDEDEGEEEEQGKGAEEKKVAEDEEGDEARAAFTEMFIGERSMTGAESIMGEATSSASPTTQQPQELVLPTSKKRRSTNETVNTKKTAKSQGKTKAPKIPKNAPTAKSKTRVPTREPSKAISAQIQRASDDFGEFIERDPLLDELEPVESSFWGNDFSVTGGLPSENLCDSSEHFDYEPVRLTENALKITAGSFRRFDETENEATEASKNCNNLGICNRNWIMDPNLVGPSFAEKLVYDGVPYDEEVAAEDAIEYYDDEDEDENEDNWNTSILSENADETNDECCESPSNCECECEESSCSTSYCHTSTSISSYKEDDNTVGRRTAPTPLESSGTDNEHRLEIEGEGAYEETMYNQTVAPPARFSENVAAKYKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCF6</accession>
    <name>A0A1D2NCF6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyribodipyrimidine photo-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000092">
        <property type="protein sequence ID" value="ODN02944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCF6"/>
    <dbReference type="STRING" id="48709.A0A1D2NCF6"/>
    <dbReference type="OMA" id="RCRMITE"/>
    <dbReference type="OrthoDB" id="496749at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000110">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052219">
        <property type="entry name" value="Photolyase_Class-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211:SF0">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTO-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="2">
        <location>
            <begin position="79"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="320" mass="36247" checksum="D31E94B79818C0AA" modified="2016-11-30" version="1">MAGKSKAPEKKASSSSSKGTAKEDDAPAEKKKKEVEDFDGFNARIREQRKSEGSSQTFKFDKSRCRMITEDENLPASHSGVLYWMSRDQRVQDNWALIYAQRLALKEKVPLFVCFCLVPKFLQATLRQYAFMLKGLRSVQKELVDLNIPFSLLFGEAKAVLPDFVKKHKIGGVVTDFSPLRTPRAWVDEVAKKLPEDVPLCQVDAHNIVPVWVTSEKLEYAARTIRPKIHKHLPDYLTEFPDVISHPHKSSSKFENPFKNWDELMAFLKIDKTVGEVEWAKPGTAEAFQTLRSCDVSKLDFRSAGQRDDPDSGLTAVLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCL9</accession>
    <name>A0A1D2NCL9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_03648</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the P4HA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCL9"/>
    <dbReference type="STRING" id="48709.A0A1D2NCL9"/>
    <dbReference type="OMA" id="ASLKCYY"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013547">
        <property type="entry name" value="P4H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08336">
        <property type="entry name" value="P4Ha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0847">Vitamin C</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="14">
        <location>
            <begin position="473"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN03007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="608" mass="70081" checksum="8FD4C8991BD7A0CF" modified="2016-11-30" version="1">MGAEETDYKSNPSRCNTLSLHWGVISIYFIVSFVVIFLSQVTGAFQPYSHTDPDFAASIHHLKLLVLAELNLLPSIFYVANKEPYRENDEPIKLYLDDFTSSNLKSLKAKISLEQFIFLLNSSYIKEDIVANDVVKHPFKSYRTIRRFVRFIGKLPEFTENEDLIRVWNHTRKLYKFPKESDLNASMESIIRLRQVYRFSINDILEGNLEMEIGSGLSIRHMVEIADHSCNLQLYSHAIDLYYGVMTKCSESQPRSFQDCSLLDLANIAVKLNDVIKKHDNLLVEWNDDLAPPDSSPHVFDDILDNITSPKFLSRKPLQIDHKMDELLKTKSELSQLYKDMIVSPFLYEKLCRGEQLRDKAVIASLKCYYSHKSHPIYTIGPLKFEVHSESPPIIQIYDIISDAEISQLQHEVQEEMRQSRTASAEGDDDLGITSRYRTSANAWIEDADISKFTYLNERIARITGLNTTGYFSSEIVQIAAYNPGNHYTPHSDAIFEDEIIKRLPESELQRGDRIMTFMLYLSHVEKGGGTGFPTLKTVIHPVKGSAVMWFNLNPDGTVNYNVLHGGCPVLYGTKWIANKWIRSNDQMFIKRCLNKREEREHYWEMPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCM3</accession>
    <name>A0A1D2NCM3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03843</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCM3"/>
    <dbReference type="STRING" id="48709.A0A1D2NCM3"/>
    <dbReference type="OMA" id="RASECQQ"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1060:FF:000014">
        <property type="entry name" value="conserved oligomeric Golgi complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="9">
        <location>
            <begin position="162"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN02825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="750" mass="85600" checksum="38DD6088BFA32C10" modified="2016-11-30" version="1">MDLIDFSQIRSLQDLDLLEKELDSKEVECDLRIKDLLSNRGDLEFQLRSLSKKLSNLKPVEAESQHFAEVIKSTALLAEDVSAKVRLLDKAKNRVSECQQRVNDLLDLQQCSEGVATAMQNEDYEQAAAHVHRFLTMDETLLKHTARDVSEGRTMDASFHRLHDAENQLKKVVAEKFDEAVKDDDLASVERFFKIFPLLNMHDDGLRRFTNYLSSKLKDSSTKNLNEARLTRETDKRANVIFADTLTLLFEGIARIVEIHQPLIETYYGPGKMLSVMEYFQKECDAQSKLIIEEFRKHRDFNKKVQIVSAYLNQRSENKIDAKEVDSVLNELTLLNARTELYARFVRRRVTSDLDISVTDEGEKATKLKNVDRLLKDGETFRVMQILLGQYILLEQYFMAQSVQKAVELDNLIEASSDDTFVVTSVTDDVFFIVKKCIKRSLVSQSVDGVCAVINNACGILESDFADLLLNQLRQGFPSGYLDLAQAYSVLQSSLQHGKIQGSDIEKNRTQFVAYLNNTDVSMEYIASLKNSLDKSITDAFGNNLSPYEKDKITNCLSGLSSVNIRLKSVSEFGFSQLKSSAVKPRVKPWLDAFFHSQRTSYEMEEDEFQDDSESMQTLISNLDAFFKSFKVCLSPTTHGTFVSMAVTEIALQMEKVLLKVKFNRIGGLQYDKELRTLMGYLTSSTTWSVRDKFARLTQIAILLTLEKVSEVADFWGKGPVAWRLTAQEVRQVLAMRTDFRQEDIRRLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCP7</accession>
    <name>A0A1D2NCP7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hexosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03652</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCP7"/>
    <dbReference type="STRING" id="48709.A0A1D2NCP7"/>
    <dbReference type="OrthoDB" id="115198at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF3">
        <property type="entry name" value="BETA-1,3-GALACTOSYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="414" mass="47764" checksum="147950CB95CD4749" modified="2016-11-30" version="1">MSSIEVENQMPSNLVGRKWRQRKGHPNVMIVLVLLAILVGCAFYILIFPWELESSEPDYYYNRLESNKSTFEPTQFRKFDKPNVLFRSTDFKYLSGIPDRKSLCKPSVNKTKTILIMVTSLRRNIGIRELIRRTWGSLRRVPKWSIKLVFVLGAKQKFQDESIYKSILDQEIADRKDMIIGNFDEEYGTRKINTHLMAYKWALTFCFNAEFILKTTDSTFVDIFQVIELASFTSPINTMVCGKRQGYKTEEGWIPEHCRPEAMLLSMDVAERLYLTTSGFDELDTGVGDNATSLMTVETQLGPDDQILITGDVVQSLDIPVTDIANQFLNEPATAFEWARNGKQSRDQRLHCMFVVMPDATDFYAKKGITDLWRKILKVNSLVYEFQLSHSPRIQTLQQEIEANFKDAPHKLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCX7</accession>
    <name>A0A1D2NCX7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phenoloxidase-activating factor 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Prophenoloxidase-activating factor II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03589</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000087">
        <property type="protein sequence ID" value="ODN03108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCX7"/>
    <dbReference type="STRING" id="48709.A0A1D2NCX7"/>
    <dbReference type="OMA" id="NHYDCEQ"/>
    <dbReference type="OrthoDB" id="5949700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000038">
        <property type="entry name" value="Serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF142">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905374" description="Phenoloxidase-activating factor 2" evidence="7">
        <location>
            <begin position="22"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="416"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00068096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00076468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="671" mass="72075" checksum="5F42F03165C5E07F" modified="2016-11-30" version="1">MRCLARENVLILALMPILVLAAPEPLKFPDSGSDSTVSGDSVLAAASTTVEQGSRDATKAIEEILSAARAGRNVGISIGDTNLDKLATDPELRKTLETEGDSGQEVQARNYISTKLCALGLAKCGEGRNYYGGNNNNGGGLHNIRDVTLVQPVVVKPVGHPIQAIPLQGSSRPFSPSNSKSDYPSLYPAETQGGFIQSSGNNNRGCSCVPVSQCNSYDIVSGPGGSSTYNPGNNNNYPPPYNPSNQNYNSNNNNYYPSNNNNNGNYNSNNGFITGTGRPSYGQVGAGIDPRNKLNGSDIESNATVVEASGSELNARSVPESSDSGNKTRVTRQTRDAPRVVSGGSYNTGGQCFDRQVCCRRPIGGGPQDRNPSYYPSNNNNNFNNFNNNNYPVTGSPSYGGGTCGKRNAYGINGRVVTGVQGNYGIGNGDTEFGEYPWQVAILRKEGADNVFVCGGSLIDSRHVLTAAHCIQSHRPQILRVRLGDWDVGGETEFYPHQDLDVAAIALHPDFNSGNLFNDVAIVKLDGYVDIQRYPHISPICLPDKYTDFSNKRCIVTGWGKDAWGHEGKFQHRLKEVDLPILNHYDCEQKLKRTKLGQNFVLHSGFVCAGGEPNRDACKGDGGGPLACEVNGVWQLAGIISWGVGCGEANVPGVYVKVSNYHDWIRQNIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDJ7</accession>
    <name>A0A1D2NDJ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000077">
        <property type="protein sequence ID" value="ODN03334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDJ7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="7309" checksum="5B15B33D7DCB5272" modified="2016-11-30" version="1">MRLDFLDLVQLKLYHLVFCNYEAATFRAVKNCSKITNSPPVSHQIRQEKDFLGMANLLQILVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEH7</accession>
    <name>A0A1D2NEH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Leucine-rich repeat-containing protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03022</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEH7"/>
    <dbReference type="STRING" id="48709.A0A1D2NEH7"/>
    <dbReference type="OMA" id="WAESACK"/>
    <dbReference type="OrthoDB" id="2013775at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23992">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001438">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006170">
        <property type="entry name" value="PBP/GOBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF96">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01395">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="LRRCT" evidence="10">
        <location>
            <begin position="464"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="701" mass="79990" checksum="6FBFFC3EBD8EDD6E" modified="2016-11-30" version="1" fragment="single">YATNKVSTSVKHMRFIDKQSQLGTVKMANFIKIVYVAALICVLCWTSVLATRSIEIDPEFPEFDLNLNRDDEAQEQRRQCEQMSICDISDEMDKKFTSLERRIRSLEQPVWKISGDNFRWSACAEGPCRCYPESFSVNCWRQTLDVIPQQQTIPIDTTVLDMGTNSVNAIHKHTFRGLIRLVQLDFSDNKIDYLPDTIFEELESLKYLILQRNHLDAINPRIFRDLKNLETLDISENYLAKLPETLWDNMASLRNLQLAKNKLVEWVNFDGLINLEDLDLTGNSIQTLGSFRHLRKLKRLKLADNALKSISENTFLGLRNVQSLSLQQNKIVELPPNAFIDLGEVTKIDLSDNLIKEIFRENFNGLAALKELNLARNELTTISNFTFEELVGLDRLSLHGNILESLDRNAFKGLEIISYQCWELTCSTEILTIDLELDSNDLLYVEDETFESLTSLQSIKLGKNSWHCDCNILYLANWIRDHSPIVWDYIPKCRGPTTVGGRPLHEMTFADVCDGAWLSMQRLPSRVLQIQGMIQTSDRRFYGTKLLNGQIYSLGTTDFCSCNRCTSKATAKDIGRLLCTENGLYPDDKLIGIVQQKCQPKLDDPRETLIACMTKCMMKQLNALNKKGKMKKTEASKLANVLPETHQESAKAKFETCYKSFHSKVKKESKCDSWIPFSSCFVGWAESACKTGSTTTAPEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFR0</accession>
    <name>A0A1D2NFR0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFR0"/>
    <dbReference type="OMA" id="CCELEIR"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="383"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="58431" checksum="720D7EA1FC90D6C4" modified="2016-11-30" version="1" fragment="single">NQWLNAELAKFMESCKSKVDTEDSVRKVLEDQLSKIQKEWDETKRLLCLEQVRSQDLDNQVSELHKQVGMSKVDVRYLTRTKAEVEASLAKQKEANEKLLEKMSTAESDTCTLGSKLASLEIELQSLKKEMDSKNQQITSLTKTHDEISEQKVLLKNENVTLRNDLALLQLKVQENQHLNQIISDKDVIIEEKTDAIDKKSREVKKLKNGIEELKTVLKVLDDQQQEFTAQLEKQMSTAKELENINQILKNENNDIRGQLTQCRKDLNESKSLKTFMEQRLRATENENQSLESKVQQQLTFLTSSNEELASANTALTTRVNKVEAENVQLSTVIASHIKEKEQLATETRQLTNIVVNCQEENLTLKSALKETLSKAETYKEGYEKYKEICRIQEQEMSRMQVQLSTKVEQQEKLIDFLQGQLEKQEKKKKKGILFTPKRSEKDAYTPKAGTPLSRPGVGVVTSGENLTSAKYTPVTKQTPTLPPPRKEECVLLKEKSNTIGAGYAKTGDSKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHD9</accession>
    <name>A0A1D2NHD9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02289</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000045">
        <property type="protein sequence ID" value="ODN04386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHD9"/>
    <dbReference type="STRING" id="48709.A0A1D2NHD9"/>
    <dbReference type="OMA" id="HFDEIFW"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24303:SF31">
        <property type="entry name" value="CYTOCHROME P450 307A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24303">
        <property type="entry name" value="HEME-BINDING MONOOXYGENASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="448" mass="50968" checksum="602C311758F3B013" modified="2016-11-30" version="1">MVNMNPFAAMTNLSKKYGDIYRLQLGTVKTVVVSSMRLIRKVLIEQGADFGDRPNFMRYNILFSNDRGNCTLSVSHHCFISPFVVLQHNQQQKTLAFCDWSRVQKTRRALARRFCHTGIYGDKITTAIGRSEVQLLKTLQQDMETFGCAEKRLKLNIQKACASIFFDFFCSEIIEDWESDQDFLQAVQKFDEIFWEINQSHPTDVLPGLAPLFRSHLNQVAGMGKSIRDLVVRRIIEPHMERLDKDNLEDFVDILLAHLEEAEPESMLTMDQVLFELEDFLGGHSAVSNLVGRAIVEIATVPGLSKTIYEQHFEMGNKDYILAVIYETLRKTSSPIVPHVASADAYLDGYLIEKGTMVIINNYELNTSPGCWNEPHLFIPERFLTESGKFCKPSHFIPFSNGRRACMGYQLVEKVTADLILGIIKNFDITPTCNPNILPQSCVAIHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHS8</accession>
    <name>A0A1D2NHS8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Myrosinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01884</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHS8"/>
    <dbReference type="STRING" id="48709.A0A1D2NHS8"/>
    <dbReference type="OMA" id="YQIEGHG"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000013">
        <property type="entry name" value="lactase-phlorizin hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="500" mass="57446" checksum="4E2BEB34955C5A23" modified="2016-11-30" version="1">MGSLKCNFDDGEFLCDTFPEGFIWGMGTASYQCEGAWDKDGKGMNIWDTFVRTMPEKIQDRSTGDVALDSYHHYKQDVQMLKSIGANTYRFSLSWARIFPNGRPDSVNQAGVDYYNNLINELLANGIQPMVTLYHWDLPQSLQDIGGWLNEEIVEIYGEYARFCFQQFGDRVQRWTTINEPFISGMMGYYYCNFAPCINDPEEGPYKYVHNQLKAHAQAYRIYEAEFKKKYNGVVGISLDTSSYFPFDKNSPEDAKAANRCFVFRLGWMLHPLYHGKYPQEMRELIDARSKNEGREVSRLPDFDDHWSKKLKGTLDFIGVNFYNAELVRGKDDGVIAPEWGLADGIPFFDSRLPGWNRDMNAYRTHDMNWVRCGAPWQDFTPTGIRECIKWISDNYGNPTMMVTETGCSGVDDKINDEQRKEFFKLSINAVLKSIKVDGCNVVGYSGWSLLDVWEWMSGYTIGFGIVHVDKSSPNMTRSLKESGKYLGTIFRNNGFPLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJC4</accession>
    <name>A0A1D2NJC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJC4"/>
    <dbReference type="OMA" id="MSFANSQ"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="18313" checksum="97A32FCE8EBED246" modified="2016-11-30" version="1">MSVPCPVLEPRKNQNSPLLVVELSSIKDILLIQSHVIYVTSFLKGTVNLSTLAIPLPREPRQVNISQRPDGTIVASFAASQAFDAPGVHSNNALSQTFEIGRNGASSSGSSAFNNNILGNEMSFANSQAQASRFDPFGGGFSSSAANAAANSFKNPMFSGSNAQANAFGNQFGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJQ8</accession>
    <name>A0A1D2NJQ8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="3 8">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01207</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-formylglutathione + H2O = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="3 8"/>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJQ8"/>
    <dbReference type="STRING" id="48709.A0A1D2NJQ8"/>
    <dbReference type="OMA" id="PSDCPWG"/>
    <dbReference type="OrthoDB" id="420518at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000002">
        <property type="entry name" value="S-formylglutathione hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061:SF0">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0719">Serine esterase</keyword>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN05500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="287" mass="32314" checksum="1B103298EA5902F1" modified="2016-11-30" version="1">MAGASVELVSSVKCFNGFQKVYKHVSKELNCSMNFSLYEPVKANPEEKFPVLFYLSGLTCTEQNFIQKSGFQRFASEKKLIVVGPDTSPRGCNLPGDSERWDFGVSAGCYLDALMEPWSKNYRMYSYVTKELTQLIKDNFPNTGKFGIFGHSMGGHGAMVIGLRNPDLFLSLSAFAPICNPTQTEWGKDVAFKNYLGEENRAKWNIYDSTEVIKSYDGPERNILVDQGDDDEFLNTILLPQNLKAAADSNPKVKVNLRMHPGFNHSYFFISTFMADHIEHHAKILNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKE7</accession>
    <name>A0A1D2NKE7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium-dependent neutral amino acid transporter B(0)AT3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00927</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKE7"/>
    <dbReference type="STRING" id="48709.A0A1D2NKE7"/>
    <dbReference type="OMA" id="ACANKSK"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF182">
        <property type="entry name" value="TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="792"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="825"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="865"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="974"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1006"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1042"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1097"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1200" mass="136029" checksum="5CE6ED1B3D055DFE" modified="2016-11-30" version="1">MGGGRIGSRNWDGHSRAAVVFMIPYCFMLAFVGIPVFFLELAVGQRRRKGLIYAWNEISPWVGGIGICCGWLCFVVGLYYNTLIAYCISYLIDSFTIPWKDCASATSDAQELAFCESKFSGRTSKYYWFKKTLDISGGIDEAGSYNWKLAIYLLLAWGTIWLILWKGTKSVGAVVYVTAVFPYVVLLIFFLFNFINSPAKGWLGAYRLLYPKWEYLYYPTTWLKAGSQIFFSLGLAYGVLVIFASYNPARNDCHKDAVLISLINCGTSVFAALVVFPIIGVLGYTNYEKCINRMQHVFVDQPLLTTANNYDIYFTTEAIWVSNVTSATPLYIRYGYGELSDDKNDWYYKGLIDQNKRGDSEIIETIKDNTKLHIHGKPLSEALQDCSIGKEATASGGGTGFVFVGFTEAVLHMPVPQLWSILFFLMLIMLGIDSGFGTVEGTVAALEDLTDFSRFKATRTANWTFLGIAFAECVAVGWLYGLAKISYDIRLMTGNKPNLFILICWKYVSPGIIVILLSSSVVQYTVDSINKGITYNPFRDGSDMTEKMPAYTIVIGFLLMIFCMVWIPIHIALRKSKYKLVRDDDEPAEFPEEELRGERNINVEKEADQFSNTEKALMGRAKTSIGDDSTITGDANNRNEKMNLTNNSLDKGAWGSNFSYLLMLVGYAVGFGNIWRFPYQMRENGGRTCVFDPVLDHVIRVRNTSLFLRASSWTTTKKRHDTFLGRNQSNIRWAWNLLWMSFRYPLPWTNCSTATANMADRDECYNDVNGRSSKYYWNRVTLSISQGIDSPGGYNGLLFLYHLITWLAIYLILWKGTKFVGKVVYFTALFPYLVLTSFFIANFAIEPKKAWLGAYRLLKPDWTTLYSPMVWLKAGSQVFYSLGLACGCLVLSDTGSMKNVSHLKYLSDEEKYDIYFTTEAQNWDEVAPDKPIIVRYGYGELLDEDKGNLKNTRDNELFEYIVSINSSMPPSKTLVCGISTIIALLLFPFGWGLYVLDLLDQWPANWTLLLIALAECIAVAWCYGLAKISYDVKLMVGYKPSIIILVCWKYLTPILILFLMVGSIVELQIANSGTFKYKVFDPKNSKNLVDGEYETDFPIGALVIGFVLTIFCVIWLPIQAGLRKTMLSLVKEESPADFPEEQLREERNIHVEKEEQQFSAPEKLMIGSSSLRNLQAYRDNKSQMDVHSMDIHIKDHRIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKN1</accession>
    <name>A0A1D2NKN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKN1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905683" evidence="1">
        <location>
            <begin position="20"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="573" mass="66281" checksum="0E01D3C0CFC89828" modified="2016-11-30" version="1">MERLYTWPVIILLLHLQLAVPTHISICYRDTTYEYPLESCPGGIQLRNVGKWFSRSRSRACISGDGALLQFDGEGTPWEDNIFPRSFPDEMKPFIGNWVDYHLQSDYELIQGNKTSILFIDARKFQQRRNFPTKTLELVVTPYETNRLAGRYTIELKRGLNNHAKQYDELLRTVIHNTQDPVLIALDPNDRSSKVCAFHPEKPEVVLTKYITSAWNVDHLEDDCEDNVFPTYERKRLDCPINDFCSTNKKVTTEGEENLHGKLEQFQQLLETMAEASVRMKHSGEHLKFHVNSNRGSGLERDQPFMAMLQRSARVFYRGFPEVVKWETLMNALSIFAVTFEGLLPSEFQVKQYDQVRIALGRCATDQDNRRADNYLSYNQTCTRNADKDDDSDDDSSSANKTDLIVTVVTNSSSSETTDPPAPAEPPTYNKLIELLWKVVQFTQAACFPSHDHHPNIHHFYASAMLELFSTPAVQLLWFQNPGWESKALDRVMLHIFPELPDNTIPTMNAILEKYEFSIHFNILQRPQLMERDKRDMRCAGHGKLIWNGRACCYLQEDDKKFRYINRVAFAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLS8</accession>
    <name>A0A1D2NLS8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLS8"/>
    <dbReference type="STRING" id="48709.A0A1D2NLS8"/>
    <dbReference type="OMA" id="ICKACCE"/>
    <dbReference type="OrthoDB" id="6768725at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN06212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="121" mass="14179" checksum="53710E97E1CCE90E" modified="2016-11-30" version="1">MPKTAQNFTTRIQQWLSKNHFRIEGEKIICKACCETFEIKTLFQLTQHVSTTMHINNICMQKQGELQQLLTEFTSKEFDEDLRKALLAADIPWTKLQNLIFKSFLEKYCEGTIPDESTVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM23</accession>
    <name>A0A1D2NM23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 domain-binding glutamic acid-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3BGR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM23"/>
    <dbReference type="STRING" id="48709.A0A1D2NM23"/>
    <dbReference type="OMA" id="FNEKEYC"/>
    <dbReference type="OrthoDB" id="9932926at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006993">
        <property type="entry name" value="Glut_rich_SH3-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051033">
        <property type="entry name" value="SH3BGR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12232:SF15">
        <property type="entry name" value="SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12232">
        <property type="entry name" value="SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04908">
        <property type="entry name" value="SH3BGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18260" checksum="965AECECC1885863" modified="2016-11-30" version="1">MGVIVYYSEISGQKEVKKRQQRVMMILDSKSIPYMPIDITDPARENEKDFMLKNAKTKGDAKYVLSPQIFNDEEYCGDFDDFELANENDELESFLKCPKAQNNNIKVANGTSRESSAEAEKKVEAPVEASETPVAEEPAPATTDEVKEVEAEPEAEAEEEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMF6</accession>
    <name>A0A1D2NMF6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Queuine tRNA-ribosyltransferase catalytic subunit 1</fullName>
            <ecNumber evidence="8">2.4.2.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00251</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>guanosine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:16633"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:18571"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:194431"/>
            <dbReference type="EC" id="2.4.2.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.64" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMF6"/>
    <dbReference type="STRING" id="48709.A0A1D2NMF6"/>
    <dbReference type="OMA" id="IDLFDCV"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.105:FF:000001">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="9">
        <location>
            <begin position="18"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="8">
        <location>
            <begin position="252"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="8">
        <location>
            <begin position="276"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="97"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN06463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="393" mass="43873" checksum="A7E4DAAA3FB59CA2" modified="2016-11-30" version="1">MGSKSALSFKILAECPVTKARTSLMTLPHGTIETPVFMPVGTQGSLKGLLPEQLEKLDCKLILGNTYHLGNRPGTDLMKKAGGLHNFMHWPHCLLTDSGGFQMVSLLELAEITEEGVKFKSPYDGSECMLTPEHSIQIQNTIGADIIMQLDDVVSSTTTGPRVKEAMERTIRWLDRCMAAHQFPEKQNLFPIVQGGLDPELRKECAKELIKRDTPGFAIGGLSGGESKDDFWRMVHISTDILPKIKPRYLMGVGFAEDLVVCCALGVDMYDCVFPTRTARFGCALTFTGQINLKQQKYSEDFSPIDPECNCSTCTNYTKAYLQKIVTHETVACHLLTVHNVRFQMRLMERIRSNIKNGTFVDFVKSFMLGIYPEKNYPTWSKEALEAVGINLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMP4</accession>
    <name>A0A1D2NMP4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_00136</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NMP4"/>
    <dbReference type="OMA" id="WRNHGST"/>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14402">
        <property type="entry name" value="UBA_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.30:FF:000006">
        <property type="entry name" value="E3 ubiquitin-protein ligase HERC2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.30:FF:000004">
        <property type="entry name" value="E3 ubiquitin-protein ligase HERC2 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000006">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021097">
        <property type="entry name" value="CPH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037252">
        <property type="entry name" value="Mib_Herc2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF155">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11515">
        <property type="entry name" value="Cul7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159034">
        <property type="entry name" value="Mib/herc2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 13" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="549"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="601"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="655"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="707"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="759"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="20">
        <location>
            <begin position="1347"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="2818"/>
            <end position="2868"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="18">
        <location>
            <begin position="3119"/>
            <end position="3170"/>
        </location>
    </feature>
    <feature type="domain" description="DOC" evidence="21">
        <location>
            <begin position="3185"/>
            <end position="3363"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="3415"/>
            <end position="3466"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="3467"/>
            <end position="3520"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="3521"/>
            <end position="3572"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="3573"/>
            <end position="3624"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="3627"/>
            <end position="3678"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="3679"/>
            <end position="3730"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="3731"/>
            <end position="3782"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="4535"/>
            <end position="4586"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="4587"/>
            <end position="4640"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="4641"/>
            <end position="4692"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="4693"/>
            <end position="4744"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="4747"/>
            <end position="4798"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="4799"/>
            <end position="4850"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="19">
        <location>
            <begin position="5053"/>
            <end position="5371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1515"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1873"/>
            <end position="1945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="2783"/>
            <end position="2803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="2875"/>
            <end position="2903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="5393"/>
            <end position="5425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1519"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1882"/>
            <end position="1900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1909"/>
            <end position="1918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1927"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="2788"/>
            <end position="2803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="2877"/>
            <end position="2892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="5396"/>
            <end position="5411"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="13">
        <location>
            <position position="5348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODN06550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="5425" mass="594816" checksum="1973224919790D0E" modified="2016-11-30" version="1">[encoded data, 5425 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMZ4</accession>
    <name>A0A1D2NMZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00094</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2NMZ4"/>
    <dbReference type="OMA" id="PCDDNGH"/>
    <dbReference type="OrthoDB" id="7775224at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905792" evidence="8">
        <location>
            <begin position="20"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="167"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5 6">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5 6">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5 6">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN06621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="460" mass="48616" checksum="CA31FE55E59E84EA" modified="2016-11-30" version="1">MALLRILSLFLCMGSLAYAQLLPVLKNPELLQKPSSNLILTLRNPLDPIFSDVASRAFPNREARLQELTRSLQEATQTWHAPIMTALKPFNVQAESFWVTNQISVKNANPLLVRFLRGLAILREIAEEIIYPIMPIFNPSIGTPPNGTEWGVRIIGAEEVWKKGNKGEGVRVAVIDTGVRASHTALRENYVGAANNGWYDPIMRSPVPTDNNGHGTHCTGSICGNNGIGVAPNAKWMGCRGCDNAGCPQAALLACGQWVICPTDAQGRNQDCSKAPHIVSNSWGGGGGGTWFNDVIKAWNTAGIIGFFAIGNEGPNCNTAGSPGDQAGIISVGSTNINDTVSSFSSRGPKNVPDGTVAPLIVAPGENINSAYHLSDNGYQVLSGTSMATPHAAGAAALLLSGKPGTTIQQMMDVLYPTTNRNLGATGSTCGNNAETTYPNDVAGYGRIDVSKAFTTLTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN19</accession>
    <name>A0A1D2NN19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein still life, isoforms C/SIF type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NN19"/>
    <dbReference type="STRING" id="48709.A0A1D2NN19"/>
    <dbReference type="OrthoDB" id="8059989at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="87" mass="9436" checksum="2A15E75B47833DED" modified="2016-11-30" version="1">MSRISDDERMSLTTAVSDDEPGDGANSPKGSRKPAASFNCTGAVRKAGYVHALCFYCFVENGRPPFSHLLLPRNIVMRCDDNNGDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0Z0</accession>
    <name>A0A1D2M0Z0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transforming growth factor beta-1-induced transcript 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_20056</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007926">
        <property type="protein sequence ID" value="ODM86626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0Z0"/>
    <dbReference type="STRING" id="48709.A0A1D2M0Z0"/>
    <dbReference type="OrthoDB" id="1112565at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030018">
        <property type="term" value="C:Z disc"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM86626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="98" mass="11381" checksum="2CF515D2CBED1371" modified="2016-11-30" version="1">MKMNFMKRMESYCVDDFLNLFAPKCKKCRTPITDDYCLVALDADWHADCFRCRDCNCLLEDVNFFEINGEPYASNTFMLVNVPIVFAFEGHKIAISES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1M2</accession>
    <name>A0A1D2M1M2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein roadkill</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006935">
        <property type="protein sequence ID" value="ODM86865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1M2"/>
    <dbReference type="STRING" id="48709.A0A1D2M1M2"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="155"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="22986" checksum="9B72F7CBC4DE8C9B" modified="2016-11-30" version="1">MASRPAKRSRSNDDEPESSMGETDVDQDVFSFVWTINNYSTQLELGAVESPVFAEVQRTTTAGGPGMEIIRFSRLNGKWGYDDFAPADLLNASPNLAVDDKVKILCKIWIYGDSKKTVMKFRGAKFNPSHEDRFRMSKDGIVNDLGKLFKESIGTDVTISGSKTNFKAHKLILSARSTVFAAMFNSECSRIVRTLWKLRILKMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M231</accession>
    <name>A0A1D2M231_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006381">
        <property type="protein sequence ID" value="ODM87028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M231"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="428" mass="48063" checksum="EE0995F3605CC8F0" modified="2016-11-30" version="1">MIEPELRNANLTRLNTKINATNVEVDFLIPNLQILNEKYLMTDEDLINGDIEISRGRTSIIKNYSLKLSANLGYVPNVGIQVSNVAMNFGVDSFLTRTANVTVIYPNGTVEDKGGWESDNAEYFNSEWVRIGADVTADAETWLNCYLSNGRNGNAKCEELLNDNWEIQNFAQLLQSIGLGIQRSRQEELAKTAVAEIKKEYPRFLPEFLVPTISSALLDIPTLFLQLGKIYGGSDERTFSGYPLSYEYDRENCTLGVCRNVQEHITVPSFSLQGLSANRVQLDFQPTNFTISLKVPNASLVSESFQREITDLESGYREIYLGLQLSIGKAAFAISGDYEFKDGVGIQVSNLGLTLLLGELQLRVPYYFTVDNGVESEIQEYKLDFAPQLMETWRGVDEDGVSFERKYEEYIQTEINALLSNSGSIQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M297</accession>
    <name>A0A1D2M297_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006202">
        <property type="protein sequence ID" value="ODM87087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M297"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903407" evidence="1">
        <location>
            <begin position="25"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="12276" checksum="0F087F9021D62CF5" modified="2016-11-30" version="1">MTSFWGIIARTILWTFIFFKQVECQLGVTYTPFVRPGDTSPTTQSYSIEDVKVMLKIISEDNFPFVSTYTVGAPNEHYQANETRYRCSSVVHTALAAAEINKEQKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2C3</accession>
    <name>A0A1D2M2C3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006120">
        <property type="protein sequence ID" value="ODM87119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2C3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="107" mass="12095" checksum="B176DAE4689DAF50" modified="2016-11-30" version="1">MTRMEQSDDPTTGITAKKGYDFQKFLKNFLYECTDIHNSTKKKPDSLILWTDDVSNKNMYAFDSLVSEKEIGDSTVENCNEDGRPFPKSTHKEFTDDKAAMVAAGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2U4</accession>
    <name>A0A1D2M2U4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005722">
        <property type="protein sequence ID" value="ODM87264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2U4"/>
    <dbReference type="OrthoDB" id="10515002at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903410" evidence="1">
        <location>
            <begin position="21"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="66" mass="7320" checksum="F0855997E38F1A11" modified="2016-11-30" version="1">MKPTLVLTFFAIAIVGGVWAACKRPTQLPPGGRWVPNEGCKSGPNYDTLTPPRERCHCWGHCGYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3Y2</accession>
    <name>A0A1D2M3Y2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_19013</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004878">
        <property type="protein sequence ID" value="ODM87669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3Y2"/>
    <dbReference type="STRING" id="48709.A0A1D2M3Y2"/>
    <dbReference type="OMA" id="DCHRTTE"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20552">
        <property type="entry name" value="CYCLIN_TFIIB_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000008">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000019">
        <property type="entry name" value="transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="14">
        <location>
            <begin position="7"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM87669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="285" mass="30761" checksum="9E2635B62F4B4B0F" modified="2016-11-30" version="1">MSRVDSSQAQCSNHPEAPLVEDYKAGDQICSECGLVVGDRVIDIGSEWRTLSNEATGADRCRVGGAENLLLNGSDLTTIIGGGRGTAAFDELGNAKYTSRKTVSSGDRALMNAFDEISQIADRLHLPKTIVDRANSLFKTIHDGKKLRGRSTDAIASACLCIASRQEGVAQTFKEVYYYNGDLMSRFCSHLGLSNTVRNAATAVAKTAEDLGIVTGRSPLSVAAAAIYIVSQASQFKRSQKEIGDVAGVGEETVRQVYRLMYSRAEELFPTDFVFFTPIDKLPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4W9</accession>
    <name>A0A1D2M4W9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18663</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004239">
        <property type="protein sequence ID" value="ODM88019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4W9"/>
    <dbReference type="STRING" id="48709.A0A1D2M4W9"/>
    <dbReference type="OMA" id="GVGWNLQ"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903478" evidence="6">
        <location>
            <begin position="19"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="59"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="8">
        <location>
            <begin position="457"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM88019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="608" mass="67579" checksum="3ED6C8202593AC61" modified="2016-11-30" version="1">MTIPLDFLTRYAIPLVVATLFLGDVDIPQQFSIFDKTQRLSDEVLSKAMGEGEGPPESFDYIIVGGGSAGAILANRLTASGENRVLLLEAGGDPNPILDVPFAQRFYWDSEMDWNYTTVKQNRSCHLFGGNCIWPRGKALGGSSSVNGLVYNRCKPKDYDSWANFTGDQSWSWANVKDTFNRIEDYHGFHEETAGANHGYGGEMYVGKIDYLPGVEVVEEVLREKNIPIGDLNGGDEFTYGFSKIDYNIKDGMRCGTYQAFLEPILNRTNLVIYRYAYAIRVETVASGEDSHRAIGITYERHGAIRTALAQKEVILSAGVVESPKLLMLSGIGPKEHLDELNITTIVDLPVGKYLQEHPGMDVIGDKGGFTLNTTFGSNFNTSDALLQFLENGTGPMNGFLYDSGEYAPQLVNGYLNSKLNDDEAWPDVYMYIHEKLTTSPEVREEMYFSLELVRPDSPGGTIKLASSDPKDKPIIDPNFFEDLNDIERMVDVIEIMMDVFMNSTTFKKYGIQQMDSYEPCNGEEFLSRDYFRCLVQQRSFPYFHPTSTSRMGPNSTVAVVDSKLKVFGVENLRVIDASSIPFVPSGNTNLPSMLVGARGAEIILAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M501</accession>
    <name>A0A1D2M501_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger protein-likeXfin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_18623</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004174">
        <property type="protein sequence ID" value="ODM88060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M501"/>
    <dbReference type="STRING" id="48709.A0A1D2M501"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM88060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="397" mass="45417" checksum="85D87DFDA7998C29" modified="2016-11-30" version="1">MKAYILLLKHSIFQAVGLPFQTKMDVHQCKKCGKSFALKSNLVKHKKVHTHNQLHQCTLCDKNYKSKCNLSDHVKTAHSKGAKPFICKEPQCSYSSYLLPDLKIMFVKCTKVKKNTKPLIVLFAGKRLESGCPFNTKSHLKRHLKPIPGSSPTSAPNVHPRLQPRVYYTIMIKCAHKARIHPCSFCDKMFITTTIETHLVPSAHKREAAKVQIMWKRLKYHINYYHGKEKFFVPSVPKPSVQSQLNAHVLEVHCKWKISACSSFFNTCSLTTHLKDHPQISKSKNEQTLCFCSKSSAVLNAKIDRIQQTYAICSQIVSLSHLNEKPYQCSICKIRYAHQRARSQNSLFKHSRGSPRTSSLLHFLWKAYVKVGFVQPSLEGIPGNDRICEQCPTEFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M514</accession>
    <name>A0A1D2M514_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004243">
        <property type="protein sequence ID" value="ODM88014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M514"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="191" mass="22705" checksum="61FE10042EC30330" modified="2016-11-30" version="1">MCESFSHCPLIDLGIDKIGERITLFTIDGNNCILAMNHHQERNKIAAERRKLEEDKLQLKREREEFENKKKQAHLEREDHRNKMINFDRDIRRGTEFVTGTERRIHEEEQREQELLSREEVLKVELKAKLDRNIFADQILKRLHEKEEKEKKAQGKLERQAKAAEKRLKSLGKRKNKLLLTQQDTTDGAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M530</accession>
    <name>A0A1D2M530_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004141">
        <property type="protein sequence ID" value="ODM88078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M530"/>
    <dbReference type="OrthoDB" id="278212at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036561">
        <property type="entry name" value="MAM33_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54529">
        <property type="entry name" value="Mitochondrial glycoprotein MAM33-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="12089" checksum="7C6A776696F2C26B" modified="2016-11-30" version="1">MKNGDPSMSQKEPPGGIRAKPNFDVEVKKGNQTLVFSCSFFPTKWKVSRGFRRRFLSLRPVHELLGGSGISNEVHIQVSELCTNYEHYLYIELMVNLQKFLKEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M634</accession>
    <name>A0A1D2M634_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Histone-lysine N-methyltransferase SETDB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_18307</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003677">
        <property type="protein sequence ID" value="ODM88374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M634"/>
    <dbReference type="STRING" id="48709.A0A1D2M634"/>
    <dbReference type="OMA" id="EISAFNC"/>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046974">
        <property type="term" value="F:histone H3K9 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070828">
        <property type="term" value="P:heterochromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051516">
        <property type="entry name" value="SETDB_methyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024:SF1">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00391">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Pre-SET" evidence="11">
        <location>
            <begin position="280"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="347"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM88374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="508" mass="57817" checksum="81563C7368CCC0AF" modified="2016-11-30" version="1">MVQYVEACDVFRVFYQSNPVWLDVHEISRNFIENYISKYPVPSLVNLQLGSLVPVKKNGKWQIALVLEIDGIIARVRFENDMEITNVLRSSEMLATFINPVTKLNTIDPDILPEYQGSIRKVKVPLNTNVFSPHECNSGCVESYVPEPKLNRMSPLVIPLFFSWSRGVTKVGIFPQVIYGTPCGKAISSFKELIAYLITTESDFPQEYFSFNVDISVSDQFVPGRSLYKNDDASYGLEPIPIQVVNSIDKERLPEFEYIVESVLSQKLKYLKKNESDIQMCCKCVDNCKGKLNCACKKLNTNSKKQYSGYEDKRLEEYNPETVFECNSNCSCKQNCPTRVVQNGVLWPLQIFKSSKKGWGIRTLFDIPKGCYICSFAGEILCDDAFKRASRAHGSTYMACLSKVPTEKEELEASTKKKRWATFSLPMTPPKDCFTVDATIKGNVARFFNHSCDPNLFMQRVFHKTHDPRFPTLAFFTSPGQGGFRAHFQYVRCESVIPANRMISADMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M648</accession>
    <name>A0A1D2M648_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-coumarate--CoA ligase-like 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003590">
        <property type="protein sequence ID" value="ODM88449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M648"/>
    <dbReference type="STRING" id="48709.A0A1D2M648"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="24774" checksum="13215019AB79C4B7" modified="2016-11-30" version="1">MVLTEKFYKEMMTLPGVRCVFNGYGMTECAALTTTIDLSGLSNGYKLMPNIPPLSCAGRNRNLFPYSMLRYWKGTKENNEQFQDGWMRTGDLGYYDSQGFVYVVDRIKETFKYFNCHISPAELEEVTLTHPSVEEAVVVEFMIQMEETEYQELLSFLKHGIESDDFEALQDDIRMFVDSKVASYKRLRVAFTLFQLYPRTKREKSQGQRLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6Q1</accession>
    <name>A0A1D2M6Q1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003401">
        <property type="protein sequence ID" value="ODM88601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6Q1"/>
    <dbReference type="STRING" id="48709.A0A1D2M6Q1"/>
    <dbReference type="OMA" id="WANEPHA"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="6">
        <location>
            <begin position="327"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="474" mass="52716" checksum="4B9DF3E5A7661B59" modified="2016-11-30" version="1">MPKVMTTRGKMLGGSTATNFMMYVRGNKRILTDGHRRFRWGSQWNYENLLPYFKKSEDYNGAWANEPHALKYHGKGGLRNVAKCDYHPGAEELFAAALEKGYSLGDYNGANQEVFSPIDLTTQDGWRENTYRAYYKDTESRFQTVSGKPKAVGVIYKRQGLTRTSTARKEVILSAGTFESAKILMLSGVGPAEHLRSLNISVVKDLPVGANLQDHLVTLVGPFLKAPAVNPNRDVTAQAAYHYLSTGNGILAASDALAGQGFFKSPVAKPDYADLQVIHGAFALYPHLPEDMNKMFGVRVDILKKWFDPYHKNDTDARFGLLVLGRPKSLGNLTLASRNPDDNPIMDPQFLTHPDDVEAMLYGFKKFVDLYENTTALNTPLFHKPVPGCEAKMFKSDDYYRCVIRMFSFTLYHHVGTCALGKVVDGNLKWSRVLGIDGLRVIDASVIPREPNANTQAATIMIAEKGSDLIIADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7M5</accession>
    <name>A0A1D2M7M5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003005">
        <property type="protein sequence ID" value="ODM88976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7M5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13604" checksum="DC65231C1513C815" modified="2016-11-30" version="1">MELHGKQRFCKAYGRYVTGSDPQSIVIGHITCVALCTIIFITCIFGVVANSLNIIVLRRSITQGSLKDLLIILAVVELLGCLSAMIYSYVIVNILENLNRSEFVFHCFRISNIIFSICKQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8A1</accession>
    <name>A0A1D2M8A1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002847">
        <property type="protein sequence ID" value="ODM89162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8A1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="186" mass="20302" checksum="C21186FC40DA29DC" modified="2016-11-30" version="1">MSEEEVGLTSTEREGTISDDEIFELEPKGRNIMVNGVHIFECIGMFGNNKGKKFYQCGGCSFMLPVEPRTTSQTPPVERMATHIQNAHKIGDSSSATHSIPPGQHGRNELKDQVATTTSTCSLNAFSKDGKRAYTLLSTPNMEPDTEAPSPKPSTSTMAHQSSRKRQEQAGSSGAHHLDSKKTKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8S9</accession>
    <name>A0A1D2M8S9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Annexin-B12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_17290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002675">
        <property type="protein sequence ID" value="ODM89393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8S9"/>
    <dbReference type="STRING" id="48709.A0A1D2M8S9"/>
    <dbReference type="OMA" id="PWERELH"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF175">
        <property type="entry name" value="ANNEXIN A13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0041">Annexin</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903644" evidence="6">
        <location>
            <begin position="27"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM89393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="299" mass="33351" checksum="713A0772C6B5CD61" modified="2016-11-30" version="1">MAHLKAVPWLSSLLILFVVVWKSCHAHPQKPTIGDFNDFHETKDAAAIYKAMKGWGTNEKSNPFYTHTKVSKAKNGNRGGIPETLQKNMIKELKSEIGGKLSELLLSLFHKAEFYASEIHGAIAGYGTDELALTEIFCCFQNITVNAIKEAYQTEFKRDLKSEVMADVSGEFENLLSALMQDKRRRSGPHSKDAESTTAVAKKLVKAGVGIWLGTDEKKFVEIFSEASYSELAEISKEYEKLTNLTLIDSLKTETSGDFQNLLVYIVQYAENPINHYARILNPPCRRAAVSKGVIAIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9W6</accession>
    <name>A0A1D2M9W6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002380">
        <property type="protein sequence ID" value="ODM89777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9W6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903674" description="C2H2-type domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12001" checksum="1ED37B0C0E6092F3" modified="2016-11-30" version="1">MNKFIAVLALAAVASAAPGAPIGYGGAVTSYGGAVGYGAPLLRAGPSRPLAQPLLRQQVARSRPLLRAAPVAVANKPILLSTGSCCRVCPTNCSKAVAVAQSHMDPHPQYNYGYSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBH6</accession>
    <name>A0A1D2MBH6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein Star</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002035">
        <property type="protein sequence ID" value="ODM90323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBH6"/>
    <dbReference type="STRING" id="48709.A0A1D2MBH6"/>
    <dbReference type="OrthoDB" id="6357215at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="36258" checksum="8CDE54EE6A26713B" modified="2016-11-30" version="1">MWRNSTSSGPRPPGRKLTLLLLILVVLFGFIYYLHVISHTSLLNGLIYKPKYQWRPEFSELNGPDISSSDSRVIEKLKRGFLTYPNEQAYNLSEPWESDVSMGQSQVIRKVFHDQLKANYKGFFVECGALDGETRSNTLYLERYAHWAGLLIEADPSNFQSLKFKFRKAVVSNTCLSTKSYPVMVSFEQNSNQGKVSSFGVGVLEKNHVDVQCFSLITGRADILKTIDFKALDISSLSVEFIHDVEGKNAIKEHMVDNGYFVLTEVTHPNWLANDFMFVKKSFFDGLSSKVKSELEEIRESYIRDGPIVSGDKRLFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCC5</accession>
    <name>A0A1D2MCC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Neprilysin-21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_16026</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001860">
        <property type="protein sequence ID" value="ODM90656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8383079at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF241">
        <property type="entry name" value="GH26575P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="10">
        <location>
            <begin position="791"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="11">
        <location>
            <begin position="887"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="10">
        <location>
            <begin position="1532"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM90656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1616" mass="185886" checksum="00C21B188616D778" modified="2016-11-30" version="1" fragment="single">LTDFLLPTSTMFRDNGETVNGAENTPKVTPELPAPIDFRQDQNLQVDDETLRDIFPPRHHDNSLGSLQSFIMFRRGGSHESIENLTQIYKRHSLDAQSGEANLRRRHHAAKPFKRAGRNRYEFAGIAHSDLDIQISRPPLMYQMNILEWLWLQSTIGHRVILMLVGVLFTLFLLHLAFWIHLSLPADGDHHVCKTKPCRNLARRLSSSIDSKVNPCENFYAFACGTSGGISTAEEDKWYIGTDSNRISYNFDSSISLGTMLKKTEEFPDHLVLDMYKACLHEKARQSSGLGPFYDLLKKLNLYSFTNDSPLTTLDVVRAWQEFSLMGYLHPQFRNRHCEHSIHSPLWLSIVLQNCEGSNIAFDYNKLVARLYELTNPGKNASAASLYPDTKTDPRSDKHFLTYKFENLMNISAPVRISKIKIINTIKFYKDKNTYSAYCHIVRYLQWRVLNALALELTDEVRDIMININRHRYRGRIANCFHCLFTWLPFVAPDRFLNQVPDATISKQVENFNRMANQVQTAYKRMIQRVSFSGNKDNEKLSRAIVLARVRFEMVPPVLFSRINFPIYSQLFNGISLNEETHLENLLKMGQRIFQWKAGSNYTSIFYKIDDVYRTPVLIDKNQVQKYLQVENRTNVEKYRIYLPLGSIEPPFFNEGLFVADTSGLGLLFTGTLQERTVLSFAAAENNTREEIEYLTNDPGVQKVLKELNLDESESELRVGKILNEIKGFTFIKLGTLYFQSHTWKDSGKTWNNFYPFEKEGILKLLNIMLEQNRLHIVSTMVNEYLATHVHESKLRLQHLEQYDAKQLFYLTHANRLCEKVSVSELEHRYKFGPFLQSVTTNIAFSNLNDFGKAFNCPVGSPMNRQHKPCRNLARRLSSSIDSKVNPCQNFYAYACGTSGGISTAEEDKWYIGTDSNRISYNFDSSISLGTMLKKTEEFPDHLVLDMYKACLHEKARQSSGLGPFYDLLKRLNLYSFTHNTSLTTLDVIESMARILAHGLSSSAIVNVDYYINESSNYTDKRASYVITAETDVVNSASIHRYGYKLYYETVKAAFEHLTELKIGHADIETIAHDIVCLEAYLRDNLEPKKLAGVTKPCQINGGVIDANFNQPLIADFDLNLLVARLYELANPGLNASDASLYPNTKSDPRSDDFFLKNRFKHLMETSAPVRIMRYLQWRVLNALALELTDEVRDIMIDINRHRYRGRIANCIHCLFTWLPFVAPDRFLNQVPDATISKQVENFNRMANQVQTAYKSMIQRESFSEYMSADSAITKENVNLLRAMLLAQVSFEMVPPVLFSRDNFPIYSQLFDEISLNEEDHLENLLKMGQRIFQWKAGSNYTSIFYKIDDIYRTTVLIDKNQVQQNLQELTTSGGKKYRIYLPLGSVEPPFFNEGLFVADTSGLGLLFTGALQERTVFLFATKKKFGSDSKEVQYFINEPGVQKVLKEMNLTESMSKEQVRKLLVAIRNLTSRRLIALHNQTDTWVDSGKTWNNFNPETTEGTLKLLTIMLEQSRLHIVSTMVDEYLASNVHESKLRLPHLEHYDAKQLFYLTHVNRLCEKVSVSELEHRYNFGPLLQSITTNIAFSNLDDFGKTFNCSVGSPMNREIKVTYWSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCL3</accession>
    <name>A0A1D2MCL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lipase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16056</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001876">
        <property type="protein sequence ID" value="ODM90624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCL3"/>
    <dbReference type="STRING" id="48709.A0A1D2MCL3"/>
    <dbReference type="OMA" id="NDRRECH"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="7">
        <location>
            <begin position="14"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="36795" checksum="83929BE865638553" modified="2016-11-30" version="1">MSLSSDCWNFQPGSRNLPFKLADAGYEVWLSNGRGTTYSLGHTKYDANKDIAAYWSFSFHEMAIYDLPAVIEKMLKETNTKKVFYVGHSMGTTQYFIGLSEIPELNDKIAAGFMFAPIAYVGHMSSVIRLIVPLLGPYAQYEVANLALLGRIQGGGQYRKLFKVSPGDLCDLTATKCGVCDNLVFLLFGYNAGQMNNTELPNILAKLPNNIAVKWLSHYAQLIATCKFQKYDYGPIKNMKEYGSNQPPEYNLQNINAPTYFFYGEQDNLGPPNDVKITASKMKSGVLKGNYKVRNKYFNHVDFIMAKDADRLIYNKVLSEMRKYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCN8</accession>
    <name>A0A1D2MCN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">DnaJ subfamily C member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_15923</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001804">
        <property type="protein sequence ID" value="ODM90758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCN8"/>
    <dbReference type="STRING" id="48709.A0A1D2MCN8"/>
    <dbReference type="OMA" id="SFWYDFD"/>
    <dbReference type="OrthoDB" id="1690618at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000180">
        <property type="entry name" value="DnaJ (Hsp40) homolog, subfamily C, member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.840">
        <property type="entry name" value="Ribosome-associated complex head domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032003">
        <property type="entry name" value="RAC_head"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042569">
        <property type="entry name" value="RAC_head_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044634">
        <property type="entry name" value="Zuotin/DnaJC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23082">
        <property type="entry name" value="Myb_DNA-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16717">
        <property type="entry name" value="RAC_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="J" evidence="10">
        <location>
            <begin position="62"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="11">
        <location>
            <begin position="536"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="12">
        <location>
            <begin position="539"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="396"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="266"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM90758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="611" mass="70917" checksum="A18AE466643DF472" modified="2016-11-30" version="1">MTHILFHPLSNVGENVLTWVKSQHDRRLFKWARELEPEQEIDGESDLTYLRGLDPVQWKDQDHYQVVGLRHLRERASEEDIKKSYRLRVLKHHPDKRQAAGELINTEGDYFACIVKAYEILSNPAKRRAYDSVDPLFDDYTPPKSVKSPEEFFTVYGKWFALNARWSNDQPTPLLGNMFSTRNQVDDFYQFWFDFDSWREYSYLDEEDKEKGQSREERRWIEKQNKAQRAKLKKEEMARIRAVVEQAWSLDPRIALFKEISRREKIEKKLAKQKVVQEQKDELEKVRLEEERIAREELERQQAEDRERDAAAKKIKEAQKRALKKERKTFRTLCKSSNYYSEDEKSTVENMASMEELCEILQLEELTRLNESLAKLSIDEGRTEFERTVQTVAQRISDENAKTAQDAYKDSDNSGGGGGGSRRGKGDEQWCHEELQLLIKAVNLFPAGTAQRWEVVANFLNQHYQGSSGKKRSAKEVLAKAKDLNSSDFSKNSLKEEANQKAYEFFEKNIKNPGAAVVVESEETKREEGVVNNKSGPVAEPNAWTAAEQKLFEQALKTYSASAHPADRWDRIAECVPGRSKKECVARYKELAALVKAKKSAQVVKQDNLHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCQ0</accession>
    <name>A0A1D2MCQ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ATP-sensitive inward rectifier potassium channel 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15964</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001826">
        <property type="protein sequence ID" value="ODM90719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCQ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MCQ0"/>
    <dbReference type="OrthoDB" id="273257at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005242">
        <property type="term" value="F:inward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034765">
        <property type="term" value="P:regulation of monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1400">
        <property type="entry name" value="G protein-activated inward rectifier potassium channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041647">
        <property type="entry name" value="IRK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016449">
        <property type="entry name" value="K_chnl_inward-rec_Kir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013518">
        <property type="entry name" value="K_chnl_inward-rec_Kir_cyto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767">
        <property type="entry name" value="INWARD RECTIFIER POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767:SF102">
        <property type="entry name" value="INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17655">
        <property type="entry name" value="IRK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01320">
        <property type="entry name" value="KIRCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="domain" description="Inward rectifier potassium channel C-terminal" evidence="13">
        <location>
            <begin position="22"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="178"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM90719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="224" mass="24696" checksum="24E3EB34BE736488" modified="2016-11-30" version="1">MMSPRNEAKPLYLARMPWYAKKRSKLLETHVRAQVVYKKTAPDGEVESIVQKELEVGALEEDEDRILLYWPTTIVHEINEDSPFYEMSCDDLAKAQGNNGTGGSDWELIVVLEGVVESTGMTTQARTSYLPSEILWGRKFRSMMKSKGGAYLVDFDLFNSTISCDETPLCSAKAWDSQNQHRDSCSSSGSSNEAVEADSAGNSGCRRGAAEGNKDEANDTSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCX4</accession>
    <name>A0A1D2MCX4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001770">
        <property type="protein sequence ID" value="ODM90848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCX4"/>
    <dbReference type="STRING" id="48709.A0A1D2MCX4"/>
    <dbReference type="OMA" id="SCEVEEC"/>
    <dbReference type="OrthoDB" id="5803930at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="481"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="579"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="632"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="674"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="702"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="737"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="805"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="836"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="879" mass="102051" checksum="AB9502D173667A0F" modified="2016-11-30" version="1">MNQSHDDDDCQLLGLVLDSDLLAMHFWSEFEDTSMPTLIPSWNSKFSIKTDEVQVDSPSPFIKLLKFAQNYLGISTAGTIIEQLEGVVNDDHPGKLGKKDEVFCEKCDVAVVNPICQIYVQLLSLRLRLSWELDHLGGLLHSSKKGVNGGKGLRMLLGSLSRREGVLALPKVHLERLNDLPLLSKSEPVFFAEDDDFHDEFFDAGDVDCDEKDDPTFQPEEPPMEPMEIEMPPEKQLKRRRIRRARSTKTRDGQNWKCEHCRKVFLNENRFQTHQLCHHKPLSCHFCELTCNGTNSLEAHVGSEHPQEQLRLACPRCSKTYPSTVRLAQHIARFHYETRYKCFHCDFSTHTRYLFDKHLSSAHPGDDHNNPFSCKECGVSFHSGMGLGGHNARVHADKKPKPESALPKKKRDCGTGPEWQCEICGELTTNKRKHLQEHQKKSTEGKSLQCCFCHRKFSLQICLDNHLKTFHWKRLSEKGYFSCEVEECKEQFKTVLDLNSHLKTHCESDLHLCACGFGFIEENLLKLHSLLHIEPLKKAKKRYWTCPEADCEKRLQSAGLLQHHYNFDHGIRCSNWDYMKCQECSEKFGSKHQLNYHHRLTHLPRKCSVCELDLIGMKVYNEHMNVFHSEAFSCTVPTCGKRFNTEESFQTHLRSHQQPKPEKMTEELKTSEERVCQHCGKTMANKKRLQKHIKLVHQKEPHMCPHCGKVYSAKIYLSNHIIRYHPEQCEQGFKLAFQCTHCPEKFRWKSVLNRHLYKAHPDKELVDGLLECPVCKLRMESGREGLMKRHMEKHMPKEERRSLSHICHVCGREFLAIENYNSHIVTHEENQTESTLRCPICQRPFYYKHRLKTHLKTHREREAINEPVNNEGGMSPAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDR0</accession>
    <name>A0A1D2MDR0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001651">
        <property type="protein sequence ID" value="ODM91147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDR0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903867" description="CUB domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30734" checksum="92A1BB8986D27E11" modified="2016-11-30" version="1">MNLRGILATCVCAIFHFTKSENVDSISNSISTQPRILTVCGQTLIADSGTIQYKLNQTYDADELCVFMIRFESGYLQATFSLESNGLSDVDSDAVSIFKDLGGLVSVVNLGLDRQNVTFNAVGAVVIFRTNSSSGTGFQLSFTCDGVIFPDTKIFGESVLFDDEMGSPLTFPFPSNITAPVIHNYFFFTAGSKLISEPDTFLRLNLTAVLGDVDDTCFNLIEIHSFETELKFEKSICEIKDDGVLFEFATRGLFFVMQRHITGTPITTGEITWDKVSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME81</accession>
    <name>A0A1D2ME81_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetratricopeptide repeat protein 30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15417</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cell projection</location>
            <location evidence="1 8">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TTC30/dfy-1/fleer family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001613">
        <property type="protein sequence ID" value="ODM91265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME81"/>
    <dbReference type="STRING" id="48709.A0A1D2ME81"/>
    <dbReference type="OMA" id="ETINQCY"/>
    <dbReference type="OrthoDB" id="10249577at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120170">
        <property type="term" value="F:intraciliary transport particle B binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039941">
        <property type="entry name" value="TT30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20931">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20931:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6 8" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 8" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="661" mass="76224" checksum="1F8EB0531940CA24" modified="2016-11-30" version="1">MEIPRGEITKTVYTLIREEKHTEAVEILEQLLEMQPCSRAALSLLAHCYYYLQEFADAANAYERLTKIYPEIPEYRLYLVHCLYNATLYEQALEACKFTGNCELSSLEPELREQFTKLKAAVQYCCDEIADAKCLLEGCSQYDPDTTINKGCIEYKEGNFQEALKYYETAAKSSGFEPHLWYNRAVTYYRLLDIPNAAHYVGEIIQHGVVEYPQLGVCMASEGWDGIASVGNTRSLHDSALVEALNLKAAIEYDLGKFESAKKTLADLPPRNQEELDAITLHNHAILNLKPNPVEALKKLRFLLDQDTFPSETLQNLLVLYSRYEQYDLMADLVAVYAEYKDKYLSPFLQSFFEALIKRESAPDESLKLFEKLCMQLSDNLRKMVKQVEDYKIGGDEELAKKLCSEYDETINQCYLPVVMQMGKVHWDRDDWPGVEKILRQAVEFCDDRDCWMLNAAHVIFMRGEDYAEAASFYEGVTRKYLDKILEVSAIVLANLCCSYILIQNNDEAEMLISRIESQEEEIIGKYPDIKVYHLCIVNMVIGTMYCVKKNYPFGISRIIKSLTDFSIRLGPDTWFYTKRCLLSLMEETVKHKLTFETDILKECMDFLIKCEQHGTSISSVVEEQNPLTEQSEALPTTYGTKTVAYEARYLRWLLYKLLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEL4</accession>
    <name>A0A1D2MEL4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001545">
        <property type="protein sequence ID" value="ODM91439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEL4"/>
    <dbReference type="STRING" id="48709.A0A1D2MEL4"/>
    <dbReference type="OMA" id="ATAYENH"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="101"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="27494" checksum="943E09DB78AC0F01" modified="2016-11-30" version="1" fragment="single">MDLLKLVYLYAFIVCSIYNSKLCNAVSVEQDLSLTKAEKLALDKFKQEVIHLMPEAYMKEDIYLIRWLRAKNLNQDQAKELLLENLRWRKMNNMSRIHQEDWSDLQEDYQYQIDSFDKTGRPIATLRFGEWDIRRACVSGKAQRLTRYLYKALDEATAKVRSLQSEGKQVSQWTSVLDMEGYAVSTHGCFCCLGIYLSYATAYENHFPGSVHDIILVNTPSIFEVVLRITKPLLGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH08</accession>
    <name>A0A1D2MH08_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001303">
        <property type="protein sequence ID" value="ODM92182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH08"/>
    <dbReference type="OrthoDB" id="7635471at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="251" mass="28196" checksum="CD8FF0E2F8618BFF" modified="2016-11-30" version="1">MERYHEPYYGHCQGETEHGGRATSNWDGNVEGSAPASLYSEEGSSGRRRDDDKSRSSRRSHRSEKYEVGVAVEAEVGTKIDHLVMKNGERTRKDINVGLHPAHQSPDLVPDPVPDPQIEEVDIGEDGGIVAILAHPVTTTGKNICSFAEYFTGVTVNPNERIILKFGYFSDHHGDNRWDYKTQYDSYKYQEPNSTIMVRGLALHLTENDIRQDVLKCGIMVKDIRFSTPQKYGVPGVSEDIRIRALNESSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH10</accession>
    <name>A0A1D2MH10_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001283">
        <property type="protein sequence ID" value="ODM92255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH10"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="34132" checksum="140F88607F9B5063" modified="2016-11-30" version="1">MQDDCASTSEGFDVEVKQEVVFPPELNSEDVKPCYSELNWEHEFQSGYVHSEEPIWSHFAVYLEELSEYNSTKSGSSYVQVIQSSVSSKPPEASKTKGKTSSRSYPVRPLHPIPSNATPEEAAKIEERRKKWREAFKRRDDRKKEQKKQEEALRVKMERKREIWRASYNRRKEMVAAKQKANYNSDPEFAERRRQQWRESYKRRMEAKRAAKEEELKKKPKRFTSSPPKPKATKKRPVQTKEVAGPSKKRKVSSSPPPPPRKTTDPVQARFQTRWQNDTQKGNQFNIFPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH31</accession>
    <name>A0A1D2MH31_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Atrial natriuretic peptide receptor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001306">
        <property type="protein sequence ID" value="ODM92174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH31"/>
    <dbReference type="STRING" id="48709.A0A1D2MH31"/>
    <dbReference type="OMA" id="RCEDEFF"/>
    <dbReference type="OrthoDB" id="302535at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017046">
        <property type="term" value="F:peptide hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052612">
        <property type="entry name" value="ANP_Clearance_Receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44755:SF11">
        <property type="entry name" value="ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44755">
        <property type="entry name" value="NATRIURETIC PEPTIDE RECEPTOR 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="16715" checksum="1FF850A9699DAE4D" modified="2016-11-30" version="1" fragment="single">PVARWLKFVDKPLLTAGALTFDYTEPKTEAESEYFLTTRTGFSFKEMVEFIMTYFDRFNWRKAFLMYDKEDMREVSGNYTCKFFMETVAQYLKENKWPFGNFDLKTNNVNASVKETLAKELGLKYSGLLIVHGHKIYFLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJY6</accession>
    <name>A0A1D2MJY6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Death domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001031">
        <property type="protein sequence ID" value="ODM93280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJY6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01670">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00531">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Death" evidence="2">
        <location>
            <begin position="67"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15979" checksum="FB46A7D54AC6089B" modified="2016-11-30" version="1">MFSTSKNQHKMENLSQPESRSKDESLKLHDRLNKLVVGSKDCPTQTVFDILAKSSSASAVYQKLSGIAFNLYNSSETINEINKKLSSDPSFSNNEALNQVLENWVENRGHHATMLELYSVLGRHGIRDAADELYQAYFHSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK23</accession>
    <name>A0A1D2MK23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PR domain zinc finger protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001031">
        <property type="protein sequence ID" value="ODM93281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK23"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="686"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="746" mass="84880" checksum="1CE16978FA12D2BD" modified="2016-11-30" version="1">MDLEEREQPPAKFVEDIFPLEIWREIFSYLRSPADLISVTQTSQVWFELLNPVKVFPLIFPSLSSEDVLNYHGDPRWSEAVEHFFKFLPAHYDIRISSKSPTFPKHPLFKRFTIQELRQLLDNSATNPFALTRYLCYREDIRHSLCKREQEEVFSERTTLIQLVEKFGDQKLPETHAKLKNCLVFVRNNGKFMTEPGDANLGGLVRLSTNVDGILSHDGLVVNSCLKQLQAEALQPNLEMSKLEHLYTQLYTEVDLQHLKHLKSPLKAVKLEARYCISEVTLSEVFGTLAHFASTLRDFSFEYYMRDGEETVLGLKLTLPMLLKFQLNVGNHRLESVDFLLPCVSLERLIVQNCGSFSDNYRTGRGLPVIQFMGFESTMYNSNIWKHLPKLKVVEVNDRTETFNLFLLPVPILLEIMEKMFCFVCLDGCSSSRSISEGGGASNIFWKFVQDYLKLSNPVGVDDFDYLCGKCEQVISSVCQLYLELRGIQLRLSWKLGELGKLLEGSRGSPTPDEDDSKDEGAEVLLLVTEFGMGGDSASHLAGVRNLLTKKCAQKAGEFGRRSDIPPTVDGNIMKAEARDTLSASEHFDTDCEPKEEEDTDSEDVGEEDNQLSSSENEWEPSRDELSSSSIKRKLQIPIAKQKRIKQQSKVISSWSCELCGPVTTDNLSLHLHKHEQETPSEEKLFKCWFCYKSFALRQSVSGHARSAHSKMFSKDGHFICQVENCLATQNQNLSSDLSTLWENSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK24</accession>
    <name>A0A1D2MK24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13358</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001022">
        <property type="protein sequence ID" value="ODM93320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK24"/>
    <dbReference type="STRING" id="48709.A0A1D2MK24"/>
    <dbReference type="OMA" id="PERNIKV"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="410" mass="46755" checksum="0215A79834739DE1" modified="2016-11-30" version="1">MGFESAQDETSETNATSLFTKFSKFAENYLQISPLARTNIDEEVIDVFCEKCELSLINPICQVYLELLSAQLRLSWEMGQLGKLIKNSQGPTSDKLRVSNIKTLKERLGIGNVAQLEEFRRLVAQKCQLKRKEMLPDVIVSRCSDVKVCVKTELNYDDVDDDDDSGHLDFGTEIDTRTDADPLDLQGFTDTPESKATMIKIENGVEIKNEPVVHDPNSELSPERNIKVKEAVADLQQNPASKVSNSNRKRKPNLFDNRKSPKLNCLKCNVELSSSSEIPKHNLYHHELMKCSFCGKSFEGKKNLSYHYHRHHYKVGSFPCQDCSKVYTTSNKLRVHRNKYHKNVSRKKCPYCDLTCLTDSCLAEHVAAIHKPENHPCPHCPRTVFTTLKYLKKHLLKCPRIDQGRQGQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML48</accession>
    <name>A0A1D2ML48_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin carboxyl-terminal hydrolase CYLD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000932">
        <property type="protein sequence ID" value="ODM93703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML48"/>
    <dbReference type="STRING" id="48709.A0A1D2ML48"/>
    <dbReference type="OrthoDB" id="6287070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11830">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="438"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="734" mass="84400" checksum="289AB8877F49A248" modified="2016-11-30" version="1">MAKSEENPSELLQDSKWKYRRVFCRVPFVEYLISGTLLHSFVENEANLDGIIKSTRKAEIEVNDPWLLKALMKQGFTSVKSLILPESLIRTCAVPDVTQLESLEDTFFTESNVPAKIVHQYTTYAFKSVKNLRPGQVVVWYHPNSEFILGKVYFTGIEVRKFSNGGLTVQSSDITVFVSFQQYQTDLSRIYYEKNTDLKTRKYIYVVDCNNLLSLSNFTNLMETTSVWNFKYELRTPGTLEIKTTEQVGSSIVISPTEVIRDAVQSPSNTLYHDSPTPATECTSKLDSSKSQYLTRSKVADSPDFYKQFENKVVLDLSKTIAAQTPSRPLNAEVSNNKIETENKDTPNREQNNRNVEFRSIETSKKAKFDSDKPHTRTQQNSDTKNPLNVRPFSEETEWPPVHRASENKNVSYTDDRTQLDTFVKLPIQYNHGQFNVRGIQGFNNSCYVDSVLFSLFAFTNVFDKSLEKPKISEDNVFADSNILISKILKYSIISPLRETGFVPSTAIQKLREAMLIYNPTFNGGLMDAEDFILTLFEKICDIPKFYVFNNEAEDFVFQIHVLYQQEKKTTADLQKLLQRSFQEIDVKLCKLPFPAFIVKLPVCHGDPLFEKVLPNLVITLDRILDAKLLKSAGIGFENRMLLRAIICLKNQHYTSFVRITNDRYSHWVYFDSKPGSLDPEVVLLRNFSEVLENPTEVYQTYSPRSLSYKGIDFAMRNAYICIYEPFRVQETLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLF8</accession>
    <name>A0A1D2MLF8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000906">
        <property type="protein sequence ID" value="ODM93823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLF8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904214" evidence="1">
        <location>
            <begin position="21"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="13869" checksum="4998D0A9AC1CB8D5" modified="2016-11-30" version="1">MKLIRNWVLVATLFVHYIQADENNAEVIDMSEFQPIEDKVLDRLMEPDDGPFEKKIKKLLAEYLVASAVESVSNFSTEVSGRALQGGYYPAQTTTAANSLRLWNTCTNGKNEEDSTTTSSSLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLG4</accession>
    <name>A0A1D2MLG4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL29</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000902">
        <property type="protein sequence ID" value="ODM93860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLG4"/>
    <dbReference type="STRING" id="48709.A0A1D2MLG4"/>
    <dbReference type="OrthoDB" id="996720at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002673">
        <property type="entry name" value="Ribosomal_eL29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01779">
        <property type="entry name" value="Ribosomal_L29e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="355" mass="37266" checksum="5B00B77E0DFB9DDF" modified="2016-11-30" version="1">MGNMRDFIFRDRYPNADDIEDPISLLSGPSLKRKKRGIIWNKIQRVKKGIQRVQKKLVSVRNRITQLLKGPETSTERPKYASTAGDGGPKWKGNSGGSTGSSGSGWSGNSGNSGSGGGNSGGGGSAGWGQGQKSESGEWGGTGQKSESTGGNGWGQGQKSESTGNGWGQGQKSESTGNGWGQKNEASGGYSGSTNNNQNNQGGYGNAGKGNGWSRSATSSSSDQDSDTSVNSIITNNAPGGASSSTVVNTPHVSSNTWSSQPQPFNSNTFASSYKRSTGSGVPPVLSEMAKSKNHTNHNQNRKAHRNGIKKPKPTLSTRGVDPKFLKNLKFCRKHNLTATQQQKRAAQRKADGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLJ8</accession>
    <name>A0A1D2MLJ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000900">
        <property type="protein sequence ID" value="ODM93867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLJ8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="412" mass="45700" checksum="FC425A5B3052CA75" modified="2016-11-30" version="1">MGFNDSPPPPRPPPSGNGWSSGEKGYQRPPPPPPRPPPSGNGWSSGEKGYQRPPPPPPSGNGWSSGNKGYRPPPRDPPPPSHGWSMGHLPTPFSPNGGGGLGWHQDRDPRTTLGPFRVNLDEDDFMKHVKIKDNHHHDDYPPGYDWVGGKDKGGFSKPDPWAPQDDEDDDRPNQPGVYRILPYGPPPGHIPSGKKTGGWSSNEGRPTEPPPTAEETTTQPTTTTTLEYEADPSEYQLPPSDENYGKGGKGKGDSAANDVDSTSADSQSDSGDKKSRRQSGRPRYDEHGFQYVPWDTKKRSVKRPSILKTKDIYDKFDYDEGGTKWEEPSPTKFRSRTENSIALWKTGSNFSNSQRRDQSADDSESESSSWTYESADRPSQLCPDGRVYSNSLKRCIRIPTTKRYSNREIKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMS0</accession>
    <name>A0A1D2MMS0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12413</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000834">
        <property type="protein sequence ID" value="ODM94263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMS0"/>
    <dbReference type="STRING" id="48709.A0A1D2MMS0"/>
    <dbReference type="OMA" id="MAYLMYK"/>
    <dbReference type="OrthoDB" id="165342at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11840" checksum="2A1898EC7B22AAB1" modified="2016-11-30" version="1">MFVMFGSMNLNEGRSKEEGVLVHCLAGISRSVTITMAYLMFKMALSLNEAYDLVRSRKSNISPNFHFMGQLLDFERQLTTCQFLSPPALGSSPDSGIEFDRWNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN82</accession>
    <name>A0A1D2MN82_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000803">
        <property type="protein sequence ID" value="ODM94453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN82"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="36432" checksum="0D50FAE692F198F9" modified="2016-11-30" version="1" fragment="single">DIDPGFNIGNRPRPGRRPRPHFPRPGGHGHYTPSQILRGRSDDLNAFVSLTGGGDNMWDVTRKKPSGSPPTEPGASQDNTVPDDSFLLPQGGDIDPGFSRPSFGYRPQPPWSWIYGVINPSRPINPILRRGSDIFAPEDASDTPLPWSWIIPAVGEEYFIMTVTTTGAVSPAISDENSEGVPGSSPAPTEYGQSYTYYSAFPRPRNAVPGWQTRNVSNILPSGPEFDPARASQRRSAYHQNWPWLARQTGSQISSLTNQTATTTNNQTRFQHSIGVGLQSLSHQKRAPLSAFGTAELRHLPTNSSSRLSDGKSTRVPVLHNGANQHFHPTSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPE9</accession>
    <name>A0A1D2MPE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemocyte protein-glutamine gamma-glutamyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase superfamily. Transglutaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000727">
        <property type="protein sequence ID" value="ODM94970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPE9"/>
    <dbReference type="STRING" id="48709.A0A1D2MPE9"/>
    <dbReference type="OMA" id="ETHCEMA"/>
    <dbReference type="OrthoDB" id="437511at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003810">
        <property type="term" value="F:protein-glutamine gamma-glutamyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000090">
        <property type="entry name" value="Protein-glutamine gamma-glutamyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050779">
        <property type="entry name" value="Transglutaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008958">
        <property type="entry name" value="Transglutaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036238">
        <property type="entry name" value="Transglutaminase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001102">
        <property type="entry name" value="Transglutaminase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11590:SF52">
        <property type="entry name" value="HEMOCYTE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11590">
        <property type="entry name" value="PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00927">
        <property type="entry name" value="Transglut_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00868">
        <property type="entry name" value="Transglut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49309">
        <property type="entry name" value="Transglutaminase, two C-terminal domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="2">
        <location>
            <begin position="475"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="900" mass="103863" checksum="91C3B39A2C98F321" modified="2016-11-30" version="1">MATPTYSGIPYPTSSTTLRRDTQMGSNRDLNIMSQRRGSIGQIGQIPVTSGYVLDSTSSVIPAPSMMPTTGQLGVVGQYATGTMSSGIRADRSAETATESLIPKRVNQMDMEFQKVKLYDSRKRPDSQNFEESNGAMFSNYLAHRLARVVEDYRRYKYEEARNMSQQFSPSFLGEQQRRASSLSLTQRAGSFTQLNQIHSSRIEETGPVEIVEWFQRDNGREHRTDRYEIIQDFRRGNPVYRRGQNFFFAMRLASGRVLDLQRTPIFVTFNFGSNPSIGKNTRVCLTVTGDREFMQRDKSDWDIRVHHQDGNTLTLQVNVSAIAPVGVWSCEIQHGNEIYQCRDDIYILFNPYCSEDPVYLDNEQARREYVHNESGKIYRGTVRNPRSQKWLYSQFNDIVLPMATLFLDRYTEGNRDVIDYTQRGSPVYVSRALASMIFSKFGVLREPENREENFSTFNFTGTHSVFEKLLEQNFRPVETDQSYIASAVYVSCCRALGLPCRSVTSYRAPQDKNSLNIDMYWSEENERESDLYQPYQCWNDVWMRREDLSTPTSHIGWQAIDPNNKGYGPAPSEAIRRGEIGLSHNIYHFYSLLNSQIRHFYNNTFPEKINIDEIGRLIITKRQDRDEDDDEYEDITHLYKKKDGVEFAGTDDERLIIMNAVRGSTPRRSSITLRSTERLNLVGLAGRKEDLLIDWSPNVTSLGQPLQVSLFMQNTSNEMRSIVVNLFARPVYQSVVGRKIRQFRRQFTLQPSQREPITLEILPQDYQDRLDEDLTVRFYASVYVKETNQFWAGDEDVTLSRPKMNVQTRTNAQVDSDFPVSFSFVNPLNMTLTDCYIFYEAPGITKPVFRRCRDMRPGEMLNISDNLVPRKGGDTKLLATFNSRQLRNIQGSRVVNVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQI6</accession>
    <name>A0A1D2MQI6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative chitinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000684">
        <property type="protein sequence ID" value="ODM95337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQI6"/>
    <dbReference type="STRING" id="48709.A0A1D2MQI6"/>
    <dbReference type="OMA" id="GDETKCG"/>
    <dbReference type="OrthoDB" id="9991479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF98">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904400" evidence="6">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="91"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="154"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="239" mass="26379" checksum="52FC55A9EE9A2641" modified="2016-11-30" version="1">MAQKCLLEVLVLSVFVAGVASQSCPEPNGYFADSQQCDAYLECKEGVAEKQLCPDGLMFNDKLTEFPRYPCSYPQEVECGPRTRTQPAQSTGECPRQYGLFRSGNGPDSCSSYMNCVGGKASVSQCPEGLAFDESTIRCDWPDLVPGCEGAVFRFQCPGVRVDADLGHPRYSDPEDCRKFYVCVENVKPRMHSCAVGFVFNPDLGVCDEPQNVPNCANYYPKAVLDAIQTLKQFDNRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR71</accession>
    <name>A0A1D2MR71_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MORN repeat-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000647">
        <property type="protein sequence ID" value="ODM95599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR71"/>
    <dbReference type="STRING" id="48709.A0A1D2MR71"/>
    <dbReference type="OMA" id="HWIERNC"/>
    <dbReference type="OrthoDB" id="300500at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042814">
        <property type="entry name" value="Morn5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46437">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46437:SF1">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="568" mass="65202" checksum="50A03B78C98B2F05" modified="2016-11-30" version="1">MSNENVQQGELPQQEESEVLPEPAAPTKDEPGADLPSDGDDHHDADDELPDLDDSNEKDDKELGGDNLSDIDAEDDRDAQEKEGSARNSWGTNDTLEMGSEMSEAAERRRRSTGEEEEEDLIEVLKGPGSLDDFMKEWEEARDSDVDEEAIAATRTSSINILDLSLQTREEATPIAEYILQLLEEDLALHVQTTGIKFPEPLTKREIMRMKRGLKDTDSASSFDSNLSDILPGEPSRIRMTYEKGVSVYADMSLMHLSAEDGVDKEIQVNLHRAKKRRHGVRFSRYTQTLDMTYIPMETALLIFKQMYPQMDDYKVKEPPSRKASQERAIAIAEATDPNIDNKRKGPQIISLSNKKQLLQPLMDDYFKEERFWTGSRFLGEYKNKRFFKGRYDHPTGTKFESEFYDGHFETNNHFGLVSYPRGDTFEGEWRRGRYQSGSITFCDGLKFSGADWKYCEPPDRRFKVERYYGIKPAGMTLFSDQYPAPHVPPGMYDVGDGFYNSKTGEVRGYDGFLLRHATETEKHWIERNCRKVHESMEHIAPNFLLERIPGSYVETQKKIPLTKKRYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRF2</accession>
    <name>A0A1D2MRF2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arrestin domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000643">
        <property type="protein sequence ID" value="ODM95623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRF2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRF2"/>
    <dbReference type="OMA" id="NEWAETI"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="169"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="337" mass="38009" checksum="E52CAC9B97866B34" modified="2016-11-30" version="1">MSRKLLKFLILFDNPSLLYFPGQFLTGRVLVELEDDTPVLGLYLHILGEGCVRLKSRGQERVYDKENYIDFRMRLLGESSQGPIILSPGIHSFPFKLGLPLGLPSTFLGKHGWIQYFCKAALKEPNGLVHKNQQVFIVMSPIDLNLEPPVVAQPFHCEMEHKLGMPCASSGTVKCRLRLGKGGYIPGEKIHIWASVTNNSRVEIKATEAILTETIQYTARGKVVQTERRELTTLSRGKIKSGHKDEWINEKLVVPPLPPTNLRGCNLIRIQYELFFIVIPKSFNKKIKLQVPILIATYPLRGENNTNTGSLSRSGSKERYPTILPTYRPTSESKSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU45</accession>
    <name>A0A1D2MU45_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000541">
        <property type="protein sequence ID" value="ODM96418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU45"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="113" mass="12956" checksum="F77BE10282724B6F" modified="2016-11-30" version="1">MDMLVLVVGPRSARLQKLGSLQSNMNEQSMLCSLVPKMQVQYEHGRTYSPPKSKRKEVREHRGDKDSAEIETTVMFSQPARRGTATAAQHHPDSQFYLQNQSGQSSNFQFWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVL7</accession>
    <name>A0A1D2MVL7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_09585</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000473">
        <property type="protein sequence ID" value="ODM97099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVL7"/>
    <dbReference type="STRING" id="48709.A0A1D2MVL7"/>
    <dbReference type="OMA" id="HEEHTSI"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14092">
        <property type="entry name" value="STKc_MSK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05583">
        <property type="entry name" value="STKc_MSK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000109">
        <property type="entry name" value="Ribosomal protein S6 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000157">
        <property type="entry name" value="Ribosomal protein S6 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="291"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="391"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="703"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="714"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM97099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="993" mass="110475" checksum="14DE9A9E5D01E743" modified="2016-11-30" version="1" fragment="single">LLVRTFRFLKAMLIHRNARSVYNSNVEEKAYGKVFLVRKVGGHDHRKLYAMKVLKKAAIIQKKKTTEHTKTERQVLEAVRQSPFLVTLHYAFQTDAKLHLILDYVSGGELFTHLYQRERFTEEQVRIYIGEIVLALEHLHKLGIIYRDIKLENILLDADGHIVLTDFGLSKEFLPHEKDQRTYSFCGTIEYMAPEVVKGGNTGHDIAVDWWSVGVLTYELLTGASPFTVDGEKNTQQEISRRILKIDPPIPEDLSAPVKDFICKLLIKDPRRRLGGGPSDAQEVKSHSFFKGLSWMDLLQKKIKPPFIPKIRNELDTSNFAEEFTKMAPTDSPAIVPPNFDKIFKGYSYVAPSVLFSDNVVSEEILRPSKLVNANTATIPNSPFFDAYEVDVNSEILGDGSFSVCRRCIEKSTGKEYAVKIVSRKVDSTREISLLKLCQGHPNIVQLHQVFYDEAHTYIVLELLRGGELLDRIRKKERFTEDEASQIMRKLVNAVHYIHSKGVVHRDLKPENLLFVDESDDSDLKIVDFGFARLMPEKDTMKTPCFTLHYAAPEVIRQALGQNEEGYDSSCDLWSLGVILYTMLSGRAPFQARSRDDSAAAIMTRIKGGQFDFNGPEWEHVSPQAKNITKGMLTVDPAKRLRMGDLLDSPWLEGGMGGLLATPGVLNRSQRGAENAVGKTLNAFHQAHKEGFRLQDVSSARLAQRRKLKKSTDGRSSSSNFSSVSSGSGGSCNASKSSVASSSLSKLSASEQEKPNFFNFGEARVQEYLSSLPEDSKRSISSTVSIPSSSSVSSSNSSTMQCSSKAMCLPLQTPTFTFAPSVTFSTVAESMASSVDSIPAITVTPILNHSSSLNMSRKALPQPTGYPIYMNFEPIMTRARKRRFEQTQVSQKPDMCPGINGYSVRINTGIDSTNSGAINLVLPSRWKNTTSEALNLSSSSAAFTSPITVTPARQQNITQSLPIGNFGSDASSVSVPKLVDAMAKYKRRRIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW95</accession>
    <name>A0A1D2MW95_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II inositol 3,4-bisphosphate 4-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000455">
        <property type="protein sequence ID" value="ODM97327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW95"/>
    <dbReference type="STRING" id="48709.A0A1D2MW95"/>
    <dbReference type="OMA" id="CRRENTY"/>
    <dbReference type="OrthoDB" id="159395at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016316">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039034">
        <property type="entry name" value="INPP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187">
        <property type="entry name" value="AGAP000124-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12187:SF11">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="18"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="156"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM97327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1170" mass="132703" checksum="9DD6688066FF698A" modified="2016-11-30" version="1">MRLNKLELLALASQPDHKYEKQGVLLLRERTEGFFRRNELETERWFRLCGNLLFYLKTPDHWSEPVGVIVLENHCVSIDSSRDASSICFRFQISFQSGGGGYNFAALSEAERASWVAVLSTASFSNIKAKVERLKNELSHKIAQQSARNTHKQPSPSTQQLKAAGYVKDVSETPLCEISLSCDNLLCDSHGRAPTAKIVVHTKNSPAGQWFKYACTEMAERSSNPVFLATVTFRASDGVTESSEARFTVYDVRERITSTAIVIGQLSCLIGSLKAIDRVRLPIRSPDNSTRHVGFLTIVVWNLKREERSSTESTPCRLNPYENPGSNQYAASASLAFSHRRTQSLPPRLYCKLKVPLQTNFGLLFSHPFIQSYRFHSGLGGDIYVHEIMAESRLSYLFPQQLLSVWIAEEKELLQEMIGLGDLREPWHAVRSEMIQRHLWLINLYTQARVSLATHKGSCNFKPSSTKADTTYEFVPLNLHLQRMWVQNESLHKSGFHDTITVGAFTAYAQGYDLGGLVKMLQRFKTELVPSERGHKKTTPSPNKVILTYDSVQGIKRLRREIVERMQVIMKLAKERKTHGMHRYVDEIYQRCHLLLSICDHSLIEEAFYFLEHNKLTLPTCQAYEYDNVETGEIQELHQQNSNSVDEGIETPNSPYRFVVDVTDSGSTVEMTKQSEDKTPDSGLGIEEIVKSFLDSPSSNYYRPSEEPEPWDLTQLNIEASMISLNSKVLMLCGMGVDIQHRSLSRRTEQRQASTLDRRSTSDMAYHSLEMHELGSRQSAGVQVTHTRTASMPVDNNNRTSHLTCTSDPNTATDWSDELRSSVKKLRLATDGLLKTCRLAHSIFRLQEPSEKSKLALALKYRRDVCFSHALTSLVTGLMGRLWCRKPDPTFLYILTKLGPLVSFHSFLTYYSHEAEMFNDMIVAVEDLRTVEFIMVMGGGDEGCPPLPKVHGSRSALKVILPVPEAVFSMLALDKNWSSSFVITPVFFNVGINEQATLAERLGNFMEPQERSNLDNFARLNEYYRRFCKQMFPAKYASKRGQDDGQNLDKLLDKMHAELLSKKKKNVAIIHLSSQISRALMGLRYTSCKSGKDRTSMSVTLEQIQILSEDYDLAEHEFQSALDATRSEGCRRENTLKNIGQRKYAFNHLQVLSLPKKYRPPAGTFGNVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWW3</accession>
    <name>A0A1D2MWW3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibroblast growth factor receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000433">
        <property type="protein sequence ID" value="ODM97540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWW3"/>
    <dbReference type="STRING" id="48709.A0A1D2MWW3"/>
    <dbReference type="OMA" id="WIRIADT"/>
    <dbReference type="OrthoDB" id="5969816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000129">
        <property type="entry name" value="CLUMA_CG018772, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF36">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 9, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="45"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="159" mass="18327" checksum="C97FD3A0EC5A905E" modified="2016-11-30" version="1" fragment="single">MKDDVRYDAISTFFGMREEGKKVLSTNSAEEDEEFDFAAYSPPGPYFDKEYSKNVTALVGKTASLTCRVRNSGNRTISWVRHRDIHLLTVGRDTYTSDQRFQAVHKPHSDEWMLQIRYPQVSSNYLYLDPGHFERDSGIYECQISTTPPIGHFVHLIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXF3</accession>
    <name>A0A1D2MXF3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000417">
        <property type="protein sequence ID" value="ODM97717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXF3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904697" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9158" checksum="B43288E163F17EDE" modified="2016-11-30" version="1" fragment="single">MVSVHKLHILLMGMLVFRHGAEGQTSNNATNITILWVDLPQNLHSNRVAGNILRTECPQGQRYSNILKLCIASNTISDGNIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXF4</accession>
    <name>A0A1D2MXF4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phenoloxidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000425">
        <property type="protein sequence ID" value="ODM97648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXF4"/>
    <dbReference type="STRING" id="48709.A0A1D2MXF4"/>
    <dbReference type="OMA" id="YYMHEQI"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006582">
        <property type="term" value="P:melanin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1520">
        <property type="entry name" value="Hemocyanin, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.10">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005203">
        <property type="entry name" value="Hemocyanin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037020">
        <property type="entry name" value="Hemocyanin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005204">
        <property type="entry name" value="Hemocyanin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF4">
        <property type="entry name" value="PHENOLOXIDASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03723">
        <property type="entry name" value="Hemocyanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03722">
        <property type="entry name" value="Hemocyanin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00187">
        <property type="entry name" value="HAEMOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00209">
        <property type="entry name" value="HEMOCYANIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemocyanin N-terminal" evidence="6">
        <location>
            <begin position="94"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Hemocyanin middle" evidence="5">
        <location>
            <begin position="170"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Hemocyanin C-terminal" evidence="7">
        <location>
            <begin position="492"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="749" mass="85352" checksum="99A5885717C33472" modified="2016-11-30" version="1">MAKGTPMNFVHLFEKMSEPLGFGLRGGGGGTGDAMTYFYYQDDNMMTQALNSDTMRQTVKMMRGQMTRAKEGGMNINMVPMEMPSSMPNLRLVAELCPKNVNFCYFHPKHRQAFVVLKTIFEKQRNPDEIFKMACACRDSPMINAQLFVYALCSCLVTRRDTRHIPIPNHFEIMPDNYCTSDVVRQANKMAHMPEMPSGMAGNKMPILIDQNLVGRGTDPEHRLWYFREDILVNSHHFHWHIVFPICSPRTEGQPGYRDRRGELFYYMHHAMIARYDTERLCNSLPRTKMFDFNSLMIEEGYFGKLSSENSSKQWGTRQPFTKLSNVQTVGGPDAIGIRVEELTRWRDRILESIDIGYYVKLEANGTEKRYPLKDLKGVDVLGDIVESASGLTPHPSYYGPIGFHNMGHVLIAGSHDPTGKFREDLGVMGDVSTAMRDSAFYRWHKYIDHIFDVHKRTLDPYQLNEGEFPLVWQGIEVVPQSFYVKAANTSTRNALKTFWDTKEVDLARGLDFRRSGAGVMKTNPVVGMFTHLNHAPFDYFLKIANKTGKPQTATIRIFMAPREDENGEKFMMHEQRTLFFEMDKVSKQLQVGENEIRISSSESSVTLRDENGSSFQRLEKLFSQARTQTDVAQEAQCNCGWPQHLLLPRGTPGGTDYDLFVIVTDGSKDRVPNLERKTGCNSALSFCGVLNEKYPDARPMGYPFDRNLYTREVITSISDLTDPCLVESNQVPVSTMRTTSATLKTLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXJ7</accession>
    <name>A0A1D2MXJ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiamine transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000417">
        <property type="protein sequence ID" value="ODM97712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXJ7"/>
    <dbReference type="STRING" id="48709.A0A1D2MXJ7"/>
    <dbReference type="OMA" id="WVKCGEL"/>
    <dbReference type="OrthoDB" id="18814at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090482">
        <property type="term" value="F:vitamin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002666">
        <property type="entry name" value="Folate_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10686">
        <property type="entry name" value="FOLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10686:SF18">
        <property type="entry name" value="IP11787P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01770">
        <property type="entry name" value="Folate_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="270" mass="30321" checksum="ECE2B09E25AFE35B" modified="2016-11-30" version="1" fragment="single">VKQSIYFHRKPDSITDGDSVISDANNSPNFTDRLKRAYRMLWADFTKAYSNPYIVKWSVWWAISSAGFLQTISYIQPLWEEIAAYKDNEIYNGAVDAVHTILSALLAILVGHITIPWRKWGESLLCIISLLQGALLIWMSQTETLMIAYVGYIIFRTLYQVMITVASYEVANNITADSSGLIFGINRFFALSFQSLLTFAVADEGGFALGERNQFIVYGAYFLVLGGIFAIVVSVTVMKYFCKATSFSEIEINGGIQNESISRNNSITRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY04</accession>
    <name>A0A1D2MY04_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09124</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000432">
        <property type="protein sequence ID" value="ODM97555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY04"/>
    <dbReference type="STRING" id="48709.A0A1D2MY04"/>
    <dbReference type="OMA" id="CWISAPY"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="34105" checksum="03F3A26441107744" modified="2016-11-30" version="1">MNNRTGCEDPYLNYVISRRPFGWNFTDPPVFLPFDFEKVDPFYWVSLMETNWKVAFYAAAVYIFVIFGLQNYMKSRPPFELRKLLFIWNLSLGIFSVIGFVRYVPGFLFVLNQPNGFYKSICVKDGMDVPTGFWTLLFAFSKFWELGDTILIVLRKRRLVLIQYYHHVVTMIVVWIVGPLVEPIARWYTVLNFFVHSLMYPYFSLRAIGIRVPVFIANLITFLQLSQMIIGFTVNMTSLYHQQIGNDCVRYPISIQAFSLVYGSFIFLFGKLFYDSVIKSGRRRTEKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY18</accession>
    <name>A0A1D2MY18_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative AIM2 family protein C30D10.14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000419">
        <property type="protein sequence ID" value="ODM97694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY18"/>
    <dbReference type="STRING" id="48709.A0A1D2MY18"/>
    <dbReference type="OMA" id="SLCKHCI"/>
    <dbReference type="OrthoDB" id="7772521at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904722" evidence="1">
        <location>
            <begin position="24"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="33801" checksum="50B5EB41F3D588BD" modified="2016-11-30" version="1">MASQKLIFQGLLVLVSVICIVHSTKTIYDGSNIPKHGKIIEANYTPRGEEYQIGNLTVYETPNGSGKRVLIHIYDILGMSTNIRQVADSIADIHGFRVVIPRIFREEYWNSENFPIADQEEVDAWVEQYASWNGVAKPDVQNIINHFRTTENITEFGIFGMCYGGLISTMAATEINEVKAAGWVHPTYVTTEMANDVKVPMCLLPTLNDPDYIPFYEILKSKFGDAVYHRRFSDMMHAFSGAGGDFSNPLIQQRVEEAVDLGIVLQQNTEQLELHYNVDTFNLNKIVNFIYESMKSTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYA0</accession>
    <name>A0A1D2MYA0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000389">
        <property type="protein sequence ID" value="ODM98019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYA0"/>
    <dbReference type="OMA" id="LCSTICA"/>
    <dbReference type="OrthoDB" id="8298093at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="404" mass="46692" checksum="398131443D308FB5" modified="2016-11-30" version="1">MVDSLRLRKPTSDDCGTPKVSLCFSQKYILRFLNICYFIFFIPFRFSSAYSLDTGFKVELKKNRIQSVFCIINHGIILAWCFKCQYDTFVNKDPTQKQTALDVTMVLLGPMTSTFFIHTAWTKAEMFRWLLEADPEGKSLLPSRTQKGILEYFHNILSIICPFSSLTFYLCTLLKDTTRDLTLWENGRPTANVIELSFFGIVILSHLFDVILQIVVLVFRDRLQYFLDIIASDNATPDEVLPKFYKLKEYVFGINKRFKMLILCSTICAVPFYSKKFGEIFLSHDSLSFTNGITNVIYFVWIFLCLIMAASVNRKICEQMKDWLQRDKNYSKIPSQELTILVAEISPDSFGLRGGNYFTLTYQFVGTVVSLIITYAFIEQQQYQSFQSDATPTVSYNSSCDYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYD8</accession>
    <name>A0A1D2MYD8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucuronosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132367"/>
            <dbReference type="ChEBI" id="CHEBI:132368"/>
            <dbReference type="EC" id="2.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.17" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000389">
        <property type="protein sequence ID" value="ODM98020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYD8"/>
    <dbReference type="STRING" id="48709.A0A1D2MYD8"/>
    <dbReference type="OMA" id="QLFCVGC"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000050">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="439" mass="49737" checksum="421B8B2E665B0B1F" modified="2016-11-30" version="1">MSGGNMFQNRRKGKLAVLLNFDNTFIEEVCHKFYQNEEIIKILKAKEKFDLAFVNAVPNQCVLGLVNYLSIPHIYLGSLPLTNSHIGGVGGFFPRSFIPSPFSPFVDKMTFLERVMNFIIEMLSGHLYYQKQSAEIYRKYLGSDIPTVEEIDRNVSMIFMNTNFLLTFPRPLLPDIVEVGGMHLKQGRSDALPSDLEELLSGAKHGFIYFSLGSIVRTKNMPPDVRQKFINVFSKLKQLVIWKWDNESEADLPDNVVVRKWLPQQAVLDHPNIKLFITHGGLLSTQESVYYGVPLLGAPLYVDQDLNMKQAERLGYGLTLEITDFTEESLEDKINTIVSNPSYAQKAKQLSQIFRDQPETPTERAVFWTEYVIRHKGASHLRSGARELTPIQYHSLDVILFLGVVSITSLSVLGVILFKVLQTTCSKLHLSSTGKTKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZC0</accession>
    <name>A0A1D2MZC0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000390">
        <property type="protein sequence ID" value="ODM98005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZC0"/>
    <dbReference type="OMA" id="TRRHEHE"/>
    <dbReference type="OrthoDB" id="6605262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="852" mass="95444" checksum="B8172DC2BF52662C" modified="2016-11-30" version="1" fragment="single">AILRSIREGATVRKTLLSPSEKKELLPFSGKDSAQKRVLQQSRRHDRTTDIEDTKEVSKVKENGNVVTEITRRHEHEVFHNEDIPDSDSDEFEHIENREGAHDYSHGKSENFIEYLAVPKGGSPSQGVKIGDGAHFVSENIRTQRDGDEDLWDSVSERIRRLPKPDGLFNQINVPPNAQPSRQDALTNRPLDLDQEEYTRKNETNRWLNSHFGSSSSSLNSEASPRTPILSTPTGIHVTMTSRGSPLHSPPPPPPPIPGGGGNNNRNNSPRTLPSSKLRSKTEKEQVGKRISFGDSPARQNHSQNSVHFDLRNRHQDDVIRSVNSQIGRVSVTKSGGLWDDEPTPTPPPRSRRRNNSPDFRTYADQTRHVNLTSTMNNNNFSSRKYANDSPSYLQKSGDVGERKNYERREQSFGYNGPVTGGITRDSIDSGNFGNSGYVTKHSNQYKMNENTNPGQNAYYDNGEADVSERKTVERRERVFSYDGASQKQFHPKYIVGTPSSTMNRLKGIEHTGAVIDNSTDNRSQTLPRRRFYFGDDEGSLMGKDVSKRAVGKSLRFGTDDIDVSISNSYQNAENNRKSNSLSRSMSFTPRSVGRDRPSYNPPRLSNETKYSPTYKSNPQLLDGPDLLTPKLLQNMSRSTRDVSLSHNDQYNYSSDRNHHYESNAVNNVSSKSKRSIFDSLKKNSVDLFETGVRGSKASSPSRSMTPTGAYSPLRNNDRSLISTRASLQSPRHFGGANSPLSDDYHETYRMSSSTPDQDESKPKIKTDTTSKFSRKTIRGDDGRAIGNVESSQTTTRTTSRYKESEVMYPNGRGIHSPLGYHSDISPQQLSSGTVVIPVRDPNNNKNVHYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZG9</accession>
    <name>A0A1D2MZG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copine-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000357">
        <property type="protein sequence ID" value="ODM98412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZG9"/>
    <dbReference type="STRING" id="48709.A0A1D2MZG9"/>
    <dbReference type="OMA" id="HKYIGET"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04048">
        <property type="entry name" value="C2A_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000099">
        <property type="entry name" value="Copine 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="574" mass="63565" checksum="5C7B3ECC4FF64007" modified="2016-11-30" version="1">MQSIQNQPTFCNRNLLDKDILSKSDPMCVVYHKPRGSDHWVELLRTETIKDTLNPDFTRKVTMEYRFEEQQPLRFELYDIDSASHNLADHDFLGFIECTLAHIVAAGSQGLSQPLNPNPYVTDAPSGKPDEAGTIILLAEELASLKDEVNICFSVHSHSESNAACRLPFHWVHFQVTIKFGGSEIGTTTCFVFRPSVMYTISKLNDAGKSIIVHRSEKVTGRNPTWLPTTISVRSLCNGDKDRTLKVDCYEIGMGSTQKCIGSCNTSLNQLVELGTGGIRLRHPDGRETNSTLLVLQCQIKPIYTFLDYIQNGTQIHCCFAIDFTSSNGDPSDPASLHFFSDSTIIQDYDAGKMFPVYGFGARIPPLGAVSHNFYVTLTQSSYCYGIPGVMESYRNCIRQIQMYGPTCFSPIINHVAQMAAQNQNGEHYYILLIITDGIITDMPNTKEAIVNASTLPLSIIILAELISQPWKSLTAMQFVFHIVQFVPYRDAYSWMKSTVGPGYGAGPVSPLAPPPAGQWAVPNDATHKLAQVKLAQEVLAEIPDQLTGYMKSRGIFPGKTHSASSKSRLVTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Q5</accession>
    <name>A0A1D2N0Q5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07795</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000314">
        <property type="protein sequence ID" value="ODM98887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0Q5"/>
    <dbReference type="STRING" id="48709.A0A1D2N0Q5"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="243"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="531" mass="59948" checksum="886F1C8F9B771E5C" modified="2016-11-30" version="1" fragment="single">MASISAPNELPLSVPHASKLPDILINAGAGDASTFHFDRAPMENPPKEKKSKSKAKKEPEPIQMVDVEFGDEITVTNHDKSDWSKNGLWIPHTKGTPIAVKLWQVLPCRYHFFCNGNIMIGHGKPLWIYTFFGIIFLSASFVIFDVLPYYVTWPDLIVGSVFLFMAFISTYNLLSIVTSDPVSNHYALTGGKSAEEIASRYGYTSYCRICKISTTHTTIHCHECHACIDLLSTRPSFPYRLLVVAEKDHHCMLLGTCVAKRNYRSFFIFIVCLQIVVWIGLIVSITHLVQNWMAEGFSYAAVRALTLYLILSALVLPPGGLILIIILPFEQLYQMFPHQESVQGEGTDQTNHINLTLKEKLSIFWSNFNQKVIKKASSQIPPSKLQCVVHVPAIPRTKEVDDRLKSFHAWNFWHVQLSRIMGLHSDDPGYHSRMDDNARLLHTYKYAGYCVPVWDTEVARANETIAISIADEESVQRSAPQGKPKVEKPQRKSLFFRCFNQCVFTPPAFPAMKSSTTTDHVKPGDQTTIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0R3</accession>
    <name>A0A1D2N0R3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protein NEDD8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Neddylin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07802</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000314">
        <property type="protein sequence ID" value="ODM98876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0R3"/>
    <dbReference type="STRING" id="48709.A0A1D2N0R3"/>
    <dbReference type="OMA" id="YAGKQMA"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01806">
        <property type="entry name" value="Ubl_NEDD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000023">
        <property type="entry name" value="NEDD8 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038738">
        <property type="entry name" value="Nedd8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="5">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="8708" checksum="2283CE42D67D18CC" modified="2016-11-30" version="1">MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIFSGKQMNDEKTAADYKVQGGSVLHLVLALRGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N136</accession>
    <name>A0A1D2N136_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Polypeptide N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="17">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Protein-UDP acetylgalactosaminyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_07710</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Golgi apparatus membrane</location>
            <topology evidence="2 17">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="17"/>
    <dbReference type="EMBL" id="LJIJ01000306">
        <property type="protein sequence ID" value="ODM98982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N136"/>
    <dbReference type="STRING" id="48709.A0A1D2N136"/>
    <dbReference type="OMA" id="QWFMDNI"/>
    <dbReference type="OrthoDB" id="6072411at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23437">
        <property type="entry name" value="beta-trefoil_Ricin_GALNT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02510">
        <property type="entry name" value="pp-GalNAc-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000019">
        <property type="entry name" value="Polypeptide N-acetylgalactosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000053">
        <property type="entry name" value="Polypeptide N-acetylgalactosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045885">
        <property type="entry name" value="GalNAc-T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF68">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12 17" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 17" id="KW-0430">Lectin</keyword>
    <keyword evidence="16 17" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 17 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="18">
        <location>
            <begin position="535"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM98982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="658" mass="74716" checksum="6E08AE7709AE5859" modified="2016-11-30" version="1">MRQVLLNLVETELKRGIFSVAVKLLWMYTWCRDHKLTDHSGLHNEILISCIPSAYGSGSANLTKGKPIRFGQHQMKMKTIAWKRSRVLKLSAIGGIFLIGLVLFIRSGDNGSGSPTWGIKSSLIAKKAPWFTEGKLGNFEPAEEPIGDGPGEGGKPYRLPADKQNEVDESIGNYGMNMAVSDAISLERAIPDTRQAECKNWNYPENMGLKASVVLVFHNEGFSTLMRNCHTIIKRTPPEMLEEIVLVDDFSDKEDLKEKLDTYITRFNGKVRVIRNTQREGLIRTRTIGAEESKGDVVVFLDAHCEVNRNWLPPLLAPIYLDRTTMTVPIIDGVDHTTFEYRPVYSPGTLFRGIFEWGMYYKETEIPPEMDAERQYKSAPYKAPTHAGGLFAIDRQYFLDLGAYDPGLLVWGGENFELSFKVWQCGGSLEWVPCSRVGHVYRGFMPYNFGKLAEKKKGSLIHINYKRVIEVWFDEKYKEFFYTREPLARYLDSGDITAQLAIKEKFKCKSFQWFMDNVAPDLLLKYPELPPNLFWGEFRNKGTNTCMDTMGRPAPTKMGLSGCHGAGNNQLVRLNAQGQIGIGERCVDADKSSVKLIFCPLGKVDGPWEYDETTNIMKHKTTGKCLTVHPTNSNLMLRDCDPGNTYHQWSWKKLKPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1M3</accession>
    <name>A0A1D2N1M3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Lysosome-associated membrane glycoprotein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Lysosome-associated membrane protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_07577</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell projection</location>
            <location evidence="4">Dendrite</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="17">Cell projection</location>
            <location evidence="17">Growth cone membrane</location>
            <topology evidence="17">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cytoplasmic vesicle</location>
            <location evidence="15">Secretory vesicle</location>
            <location evidence="15">Synaptic vesicle membrane</location>
            <topology evidence="15">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Early endosome membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="20">Membrane</location>
            <topology evidence="20">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Recycling endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 20">Belongs to the LAMP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000299">
        <property type="protein sequence ID" value="ODM99101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1M3"/>
    <dbReference type="STRING" id="48709.A0A1D2N1M3"/>
    <dbReference type="OrthoDB" id="6232933at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072594">
        <property type="term" value="P:establishment of protein localization to organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048528">
        <property type="entry name" value="Lamp2-like_luminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002000">
        <property type="entry name" value="Lysosome-assoc_membr_glycop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11506">
        <property type="entry name" value="LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11506:SF35">
        <property type="entry name" value="LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01299">
        <property type="entry name" value="Lamp2-like_luminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51407">
        <property type="entry name" value="LAMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 20 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0770">Synapse</keyword>
    <keyword evidence="6 20 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Lysosome-associated membrane glycoprotein 2-like luminal" evidence="22">
        <location>
            <begin position="84"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00053950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00074379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00076257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF01299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODM99101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="34686" checksum="1EEB1F654D8D7F32" modified="2016-11-30" version="1">MQCQPLHFRFDDLKNKFYARLNYHSLFVPWMHILMAEKVTCGKMLLLCAAVLFCLHAVGAANETTTVAPVPTPTPAPAPVYPDNTGSWNVTEGNATCVLIRAGIRLNVNYTDINNNTRKTPIDIPSSAVAIGSCNDSSEQYIRLAWYYSESHALNNTLTIVFQANATNKNESGILSANPVPLGKFAIIKVSAMLNKDEKLFPNATDAGNPFTIDQQNLVVLPTSLNHSFACASEVVVGSTSQQLSLKLQNSQIEAFKTGPGKSEDFSTAEHCAADEISSGSMIGTIVITILIIVLLALGAAALVTYVLKKRRATASGYENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1V5</accession>
    <name>A0A1D2N1V5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000290">
        <property type="protein sequence ID" value="ODM99249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1V5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904906" evidence="1">
        <location>
            <begin position="21"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11755" checksum="5FB2296B1FEDB924" modified="2016-11-30" version="1">MNQTISILFLAACIFASVTAFPAKSKVQRSPRQVTYDWVAHSPSNDYSGVTFYPAHSNIGYTYSQPYPRDNSGYYGNYGAHGLGYHYSLVSNANGYHHQAHYQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Y7</accession>
    <name>A0A1D2N1Y7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Opsin, ultraviolet-sensitive</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_07623</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000302">
        <property type="protein sequence ID" value="ODM99064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Y7"/>
    <dbReference type="STRING" id="48709.A0A1D2N1Y7"/>
    <dbReference type="OMA" id="PACACKF"/>
    <dbReference type="OrthoDB" id="2105199at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00577">
        <property type="entry name" value="OPSINRH3RH4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="17">
        <location>
            <begin position="52"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM99064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="314" mass="35342" checksum="E98CE8412D0D7DD1" modified="2016-11-30" version="1">MSQVFRMNGWNTPSEYLEYVHPHWLKYEAPNPFMHHMLGVLYVIFMFGSLIGNGVVIYIFSSCKSLRTPGNFLVVNLAICDFIMMLKTPIFISNSFNEGPLYGRLGCEIFGIMGSISGIGAAVTNTAISFDRYRTITNPFDGKLTQGKVLMLILAIWIYALPFTILPAMEVWGRFVPEGYLTSCTFDYMGDTPAIKAFVACIFVYSYCIPMSMTAFFYSKIVGHVRDHENLLREQAKKMNVESLRSNKDLAQQSAEIRIAKVAIGIVVLFLLSWTPYAICALISAFGNSYSYHDDSIELPSENESNTTQKTQNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Z9</accession>
    <name>A0A1D2N1Z9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemicentin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000292">
        <property type="protein sequence ID" value="ODM99241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Z9"/>
    <dbReference type="STRING" id="48709.A0A1D2N1Z9"/>
    <dbReference type="OMA" id="CIFTIMP"/>
    <dbReference type="OrthoDB" id="6431884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF31">
        <property type="entry name" value="SIDESTEP II, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="104"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="207"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="311" mass="34477" checksum="B58E3C1C6108801F" modified="2016-11-30" version="1">MHPPMLSLRMGSSLNPRDIKEGDDVYFECHIRANPQVHKLAWYHNGLLLHHNRSAGVILSNQSLVLQKVSRPSAGNYSCRASNVQGEGTSNHVLLDIMCKSNAPACQSELSGTDAPIIIAASRSEDVNITCEMDALPDRLKFQWTHTNTVGENSELESDMYTSLGSKSLLRYHLRSEEDFGTLLCWAHNSIGAAERPCVYQLVPADVPQPVENCSIINRTSTSVEITCEPGFDGGLPQSFLLEAYQTSPTERRGLLYNITFDRPAFSLSRLDADGTFHFKIYSVNRKGRSSASIMDGIVLHYPAMQSGKWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N234</accession>
    <name>A0A1D2N234_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000289">
        <property type="protein sequence ID" value="ODM99281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N234"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904907" evidence="1">
        <location>
            <begin position="28"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="98" mass="10858" checksum="118844B921C896F4" modified="2016-11-30" version="1">MFMPTTKPTSLLLIMAVGAILSTWLKCYECIDCTKPRFATACKEEEVQCVTTVMEDGEISRQCVREEVVKQWADVGITCETYGSPPQGNGNLGLLLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2S2</accession>
    <name>A0A1D2N2S2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calcium and integrin-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07136</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000272">
        <property type="protein sequence ID" value="ODM99540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2S2"/>
    <dbReference type="STRING" id="48709.A0A1D2N2S2"/>
    <dbReference type="OMA" id="RFKMLAP"/>
    <dbReference type="OrthoDB" id="114727at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000079">
        <property type="entry name" value="Calcium and integrin-binding family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051433">
        <property type="entry name" value="CIBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45791:SF1">
        <property type="entry name" value="CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45791">
        <property type="entry name" value="CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0401">Integrin</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="99"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="21430" checksum="ED06B2F182742FD1" modified="2016-11-30" version="1">MGSKQSVFTEQEMDDYLDLTFFTKREIELCYQKFKSLSPEQVLKDRETRLPMKMILTMPELKVNPFNDRICKVFSSSEDGDLTFEDFLDMMSVFSEDAPVSVKAEYAFKIFDFDEDDMMGPEDLEQLIKRLLGDEELHARDIKQLVKNLTAEADLDDDGLLSFAEFEHVVAKSTDFVQAFRMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N561</accession>
    <name>A0A1D2N561_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_06328</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000212">
        <property type="protein sequence ID" value="ODN00362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N561"/>
    <dbReference type="OMA" id="DGFDHHK"/>
    <dbReference type="OrthoDB" id="152385at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048812">
        <property type="term" value="P:neuron projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20956">
        <property type="entry name" value="IgI_4_Dscam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20958">
        <property type="entry name" value="IgI_5_Dscam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000017">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000093">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000005">
        <property type="entry name" value="Neuronal cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000028">
        <property type="entry name" value="Neuronal cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF56">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1880"/>
            <end position="1902"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="192"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="302"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="395"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="513"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="613"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="705"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="807"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="931"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="1077"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="16">
        <location>
            <begin position="1182"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="16">
        <location>
            <begin position="1280"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="16">
        <location>
            <begin position="1383"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="16">
        <location>
            <begin position="1486"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="1544"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="16">
        <location>
            <begin position="1678"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="853"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1988"/>
            <end position="2066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2198"/>
            <end position="2238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="853"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="2226"/>
            <end position="2238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN00362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2247" mass="246959" checksum="F11DA05FAC0DAB0E" modified="2016-11-30" version="1">MHKSQAISQELGKKTQEAHHLSPSQLLSTRVEKRKERMGHPSNKWREMMVQLVFFRVRLLLLLLLALYGLVTDWMTLLPRCNAEIYDSEGPQFISEPSRLNYFTNIQGLLLHCSARGSPSPRIHWINQKDGQPVELVSGVRELYPNGTMYFPPFAVSYYRPDIHDQVYVCIGLNSVGKIRSRDIHVRAVINQQFDVRVESAYTSEGNDALLRCVVPDPVKDYVSVTSWIKDSSLNIFPPHSGGGGRYFMAPSGELLIEDVSRNDSSSAFRCRTVNRLTDETQLSENSARLQLKGGPPSNSPPRILSRISRVRLKEGDVGVIFCLSEGHPPPNHGWLKLLNYGGLEPLRPSERVRIRRSAIIFENVIASDVGTYVCVANNTSGSDRYRIEVVVTRPLEVQVVPSVLTVDIGKSAELTCWTNRASDLSSSSQMMTTSNSQQQMMHHQQPSAITVTWRKDGTEIRPSLRISFSPSGDKLKIVTVQREDKGIYQCFVKSDSDMAQATAELRLGDSHPQLIYRFIEQTLRPGTAVSIKCSATGNPTPHISWLLDGFPLPHSERLLIGQYVTMNGDVVSHVNITSTSRVGEDGGEFQCLATNKLGFTAHSARLNIYGAPFVRNMPNTMTAVAGKLFLIKCPVSGYPISSITWEKDEQLLPSTIRQTVSQNGTLTIRDVDRGVDSGWYTCTASNKQGSSNRRGVHINVVVPPKLVPFSFPEVTREGERIFVTCVVSDGDPPIKLQWLKDSVPIHAGGNSSRPFDMSTHQIGDFDALALQIPHVNSNDTGNYSCNGYNAAGHASHTLQLIVHVPPRIAPYSFPSPVSQGSRVQVVCSVEQGDIEETNLTVAWLKDMEPIRSSGGSNSPLLPPSSSSSLAGNPQQQTTTNAKVMQVDAYSAILIIDRVDSERDSGNFTCKISNSVDEVTKTNELVVRVPPKWVDEPKDTEVVEGKSFTIPCQAKGFPTPKISWKRAMSDRPENFRDIPEITSSSSSLSVRMRSGGYQQQQQMTGSDLMMGASANSGGGGVSSSVSTSVLVDPFSFSNGTLSIHSTRKSHHGYYLCEASNGIASGLSKVIRLVVNVPVRIKEPQQNVSSPVGGNAVLQCEISGDPPLLAVGWKKGLEEIKPDLADSRYRVRVLNNSGTSTVSELTVTNVGRDDTARYTCFASNRHGESQGAILLYVQEPPDVPRNLHVIAKGSRLIRLGWILTQNGNSPLKQFIVQHKLGELAGETQESRVSGNVFSETIRKLRPATSYVFTVIAENEVGKSEPSEGLEIKTDGEAPEGKARNVRVAAVSSSDIQVTWEHPEKDTWHGQLLGYYVGYMRYREGEQYQFSTIERKEPILQEFLISGLVPFTSYEIVLQAYNGIGTGPMSDAMVATTLEDVPNGAPEGIQCSPLTSDNLQLSWNPVTGEHARGLIKGYRVTLEQVDADSLDGNGDTQLIRTTGTTNLIVNGLAKYTNYSIQVQAFTAVGNGPPSSPTYCQTEEDVPNSPAAIKAVVSSSSSITVSWQPPQEPNGQLTKYTLYISVIPDASQTRRDGVGLRKRTVPPETNKFQFEGLRPDEKYEFRVSASTRVGEGAYAITQRIQTKSVVSSIISFGEDLRIVWKTDVRFVCEIVGNSIIQWTKFSEVVRESDRTTINRDGSLVIREARRADMGNYTCTINVNNGHTGVDSITHKLTVQVPPLAPLMTAAGTSYSTVNLQWKLSDSGGAPVKGYVLHVKASDEWIERRLSRHLSAHELQGLECGTYYQMYLTASNRAGMGRASEMVNVSTLGSIPTLKLHSPQFMAQSNRTVTRVLLKDVWSGNGFGGGEQLGGERHSVDLTGLKSSSTFHIRVIATNSAGTAQTEITVNTPSAASSNGLGAETSTNVMNQLKSTPFYMDVKLMGPIFLSIIALIVVTVSACVCYRRKSPADGQSNENLSVGTPSSSLYFKQNHQALLQQPHLRNSQQMYMTVKKSTPMKGVDVSDLDTIPQYADDIYPYATFEVNEPHRDTRACSGGVVGVPTLDRKRASGRPSSGCQDNMKPTLPPHHLQQQQSREESDEYDSYGSDSDFTDKDLPSRLQQQGGNKSRYVLNMGKNAAVVRQQQQKFQDYDSHARCGNRYEFGPPQNNPALLKYHHDNGSNSKPGGIIRPLSQNDEMIHGMITSEPYAFNDSYPTALVQDKRGSGKKKSGKRKFHSANLQPYVSSSELSELLPAKYTLDPPEGFSDTLKSKPEDTAPATKTDLGMKSHNNAKPQRTQMKTANEYAIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5E7</accession>
    <name>A0A1D2N5E7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium-dependent phosphate transport protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_06516</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Apical cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC34A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000229">
        <property type="protein sequence ID" value="ODN00166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5E7"/>
    <dbReference type="STRING" id="48709.A0A1D2N5E7"/>
    <dbReference type="OMA" id="HDCFNIL"/>
    <dbReference type="OrthoDB" id="76259at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="328"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN00166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="371" mass="42672" checksum="BA387645734C3FC0" modified="2016-11-30" version="1">MSAMLQVDHRNRFRRAFAAATIHDMFNWCTTLVLLPLESLTGYLYHLSDFIVREISNGELQNSTTEVRILKALTGPLTKKIVRIDKKVVAGWIHPNETIREMAKQQSMISRKGGTLFDDILWSDIAIGLVVVVGSFVTLFFCLIILVKILNSILKGLTLTRFCMKLHTSSNIGTTTTGIIAALAQTNNFFPSLQVALCHFLFNFTGVLLFFPFPCMRFPIRMAKSLGNTTAEYRWFAIVYIVMLFFLFPLLFMGLAFAGNIYVLSAVIILVTCFLFVVTINDLRQYPRFLPKFFHTWKWLPLWLRSLEPYDNNLSKFIWCRRLQKRSSMDDEKSAKLSTVEKEEKDTEDNDEEARIILEANTEENARKDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6T0</accession>
    <name>A0A1D2N6T0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc finger CCHC domain-containing protein 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000186">
        <property type="protein sequence ID" value="ODN00785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6T0"/>
    <dbReference type="OMA" id="ANSWADM"/>
    <dbReference type="OrthoDB" id="10038672at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027377">
        <property type="entry name" value="ZAR1/RTP1-5-like_Znf-3CxxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033446">
        <property type="entry name" value="ZCCHC24_Znf-3CxxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17180">
        <property type="entry name" value="Zn_ribbon_3CxxC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01328">
        <property type="entry name" value="zf-3CxxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="3CxxC-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10822" checksum="774DCD264590D9D6" modified="2016-11-30" version="1">MSDETTKKLTPYQGDLRCFGEFQCPMCRREWKSGNSWANMGQECEKCRINVYPYKQSTLKGGGNKDDGPPHPSEMCEKCKKLGYCCRTYSRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N771</accession>
    <name>A0A1D2N771_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Integrator complex subunit 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05589</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000172">
        <property type="protein sequence ID" value="ODN01097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N771"/>
    <dbReference type="STRING" id="48709.A0A1D2N771"/>
    <dbReference type="OrthoDB" id="5600060at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027074">
        <property type="entry name" value="Integrator_9su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048660">
        <property type="entry name" value="IntS9-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46094">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46094:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21382">
        <property type="entry name" value="IntS9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="795"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="905"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="803"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="905"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="949"/>
            <end position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1060" mass="116096" checksum="4A14196D893763A7" modified="2016-11-30" version="1">MAWELCELNNVILVDSTPLFGVPFESSIDISEIDVILVSNSSSILALPFFTENPDFHGTVYATEPTVNVGRFFMEELVEFVQAVPKPKSAKSVGKWENVFKQLDPALNFPCKIGDSCFNRNLKEIYSKKSISDALLRVRIVGFNENTDIFGKVLATAVSSGFSLGSCNWILKSESQKVVYVTSSSTLTTHPSPMEQSSLKDANIFILTGLTRAPLHNPDAMMGEICMAVVHTLRNGGNVLFPCYPSGIIYDLFECLTNHLEAHGYGTYPFYFISPHAETSLAYSNILAEWLSNNKQRKVYIPEDPFPHAQLVKDGRLRHCKALHAIPELRQPCVLFCGHPSLRFGDITHLIETWGSNANNSIIFTEAEFPYLECLAPFQPLAMKAFYCPIDTSLNFHQANKLIKDLKPDVLITHEEYLTAPRAYPHRVDLVLDYPTVEKLATGSVINLKLKRSVATAVMDPILASEVEPVVRDESGTIASTITATLDNTNNKYKLVKPSMDLCDPWKCPPSKYAWGSLDSSIVMQKLLQEGFTQSKIQHNATGFIITIPSDNATVTVEPNSTHIVCTGGDATKMSVVPCKFYASGNCRYGNNCRFYHEPRNQQTAGQLAKSNTTNANSRGFFGNRTLAPATFQAQGVSPNQNALNLSKTNSNLDIIIEQVKKDMQEWQACKIWPYSCYGPVGSKVCVPGFEDLSPEEFRLAYMQSGNNVPPEVIQRFQQINQMRVNYQQSTMENRTIIERIVKADSALTVAQTVFGGGTQTSQPQAASIFGGTATQQPGNLFGGSSAFGQQQQQQPQAQTGSIFGGSFGGNTVGQQQQPSSGNLFQAQPPANTGLFGAQPQAQSAFGTVQTQQPSLFQQPQQQQQTGLFQQQATATQQAGTFFQQPGQAAVGNVFQQQPVPAAQGSFFQQPQVSQQQPAPGLFQQPQVQQSQPGSFNLNQNQQQQQQLGSTFPTPTSNIFGGGTTQQAPATVPGGNIFGGSAASFPQSGQGGIQQQQQIASQLNPSSLVPQKFVYSDESELTKEDVEAFQAQDFSIETLPLKPPPQSLCIRPYCTLQTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7E4</accession>
    <name>A0A1D2N7E4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05491</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000167">
        <property type="protein sequence ID" value="ODN01190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7E4"/>
    <dbReference type="STRING" id="48709.A0A1D2N7E4"/>
    <dbReference type="OMA" id="WSEAWIA"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="24"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="373" mass="41802" checksum="27D986FBAB3B6417" modified="2016-11-30" version="1">MDGYMLTTFRIPGGRISPARSGKPSVLLLHGMGSWSEAWIALPNDKNLVSIGLKMGLLAYMLADAGWDVWLGNNRGSSYSNGHTSLNSAFEPYWNFSWHEMGIYDLPTIVDQAIAVSGNEKIFVIGHSQGGVEVLVGTSEIPELNDKIHAAYLMAPAAFLGGAYDPFFGALLPIVNTPLEDVLYAVLRGRLQRRNPRILSTIFGIQPHALCQPRAIRCGLCDQYLLGLYSFNPTQMNYTNIPRIMAKLFDVENIKSDIHFGQNILSCMFRKYDYGSSENQRRYGSVDPPDYNLEQIRTPVYLLWAEQDTLITPPDIQRLASRLSPSTLREVIRVEDDTFNHGDFALARDANILVYRPLIEKMNAFWNEVSSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7I9</accession>
    <name>A0A1D2N7I9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Forkhead box protein B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05453</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000166">
        <property type="protein sequence ID" value="ODN01223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7I9"/>
    <dbReference type="STRING" id="48709.A0A1D2N7I9"/>
    <dbReference type="OMA" id="YCRIDPR"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20035">
        <property type="entry name" value="FH_FOXQ2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000352">
        <property type="entry name" value="Forkhead box Q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047519">
        <property type="entry name" value="FH_FOXQ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF343">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="5">
        <location>
            <begin position="128"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="128"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="219"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="297"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="581"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="583"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN01223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="649" mass="70315" checksum="AFCD59B10C918515" modified="2016-11-30" version="1">MEINPIPVRNPFPPVTSVSGSGQITPIPPPPTVSSGNMNVGQNPVGIPSQIPGGGLLSPVTASALEHYRLTQLYQYAMAAERLRVPPGSFLPQMPPGLRPELAPLFYGPYCRIDPRLAGLCRPPEEPKPQFSYIGLIAMAILSSPDKKLVLSDIYQYILDNYPYFRTRGPGWRNSIRHNLSLNDCFIKAGRSANGKGHYWAIHPANVDDFTKGDFRRRKAQRKVRRHMGLAVDDDDSPSPPPASPPPAWHHPHHAIFHPGGPHPIGNPMALAGSPQNPGLDLPATLFGLSAAAAASLSGKSPQDPSFHHHHHHPMSSSLFNRKRQFDVASLLAPEKESGGAISPNSYKSDEHDRDQSLSSPSPPPGSEGTLKRSKIFKGSRNFGPGNDSSDDESIEVTEDDGLGKQHFSRKCQGGGDNETDEVVQTQMNDSDNKINHSRDGSDCSRGASPQPQINSTSILLSPREKNVKMSKLGQCGTSSNDEDDGGCKTHNYCSNIGKWGMNQQHNIMMLRNDKVALNNSNGSSAENDGVSSTGMLRGQSNMQLPTMQQMLNQQNLMNHASNAAAGGGLPPLEILQAHHHLVQQQQQQQSQNSHQVGSGQGPPMGFPFGIPGGHQFLQQNPSLASLMLLSSKYRELTMSAGVMKRPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7R0</accession>
    <name>A0A1D2N7R0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000161">
        <property type="protein sequence ID" value="ODN01310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7R0"/>
    <dbReference type="STRING" id="48709.A0A1D2N7R0"/>
    <dbReference type="OrthoDB" id="6752441at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="360" mass="40674" checksum="395304E52DE4AB8E" modified="2016-11-30" version="1">MGHSSGAAAAHLHLIANKTTPYFQSGASFSGSAFTHWAIQSPKEAKRLTDALAYNVNCNNNNDDSEALVECLRQKNPVELVSAQYRLLEFAPFPVTLFTPVIEKPDFAAYLTKRPDTAYALGQVDSKPWMFTTTSQEGYLGILFLQSFFTEGILRSKWDELAPIFLDYKYTANNVTETTEKISRFYFGSNSPLTVSQSRIAAAFGDRLFMPGIHQAIKTHATIAPTYAYVFGFKGKYSLGSLVGRLPSEWGTQHQDDIMYFLNSSIYYPGFKRQDVDEHTLSNVMTSVITNFAAKGEPLLTQPNKVNVRIWDPVDPTNIHYLLLNRDIRMIPEPYKKRINFWLYLGQTDPSLINPLYDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8J8</accession>
    <name>A0A1D2N8J8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nostrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05139</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000147">
        <property type="protein sequence ID" value="ODN01561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8J8"/>
    <dbReference type="STRING" id="48709.A0A1D2N8J8"/>
    <dbReference type="OMA" id="HRLARFQ"/>
    <dbReference type="OrthoDB" id="28357at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043226">
        <property type="term" value="C:organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11823">
        <property type="entry name" value="SH3_Nostrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035656">
        <property type="entry name" value="Nostrin_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="1"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="508"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="449"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="574" mass="64214" checksum="B80EC560167A214E" modified="2016-11-30" version="1">MVGQNEFEELRRVVKQGGDFCKDLATVLQERSELEAHYAKGLSKLSGKLLKASKEATGSVAHAWQAVAVQIDTQAELHRQWSTALAEEVARPLRNSLETQHKIRKSVEVLVEKTTRNLAEWRTAESKAKRQCFSSSKEFEKLQESSAVIVNNNLNTANSTGSNNANSGANGNSNVNNLGSNLALAEVRTRSRLLSVPPMEKDPIKLESKRRKAEEAVRRADIEYYTFCVRSERARLEWESAIRNGSTCLRTLEEEKLSLLRDIAVKYYQYLNELAPRLVQSVESLEDPVKNCSVSQDMHAIVDIRRHAGAEQLLPDFYAEDTSNLMKRERRQEALQKFLYLVNQDLEREKKGAVGIETLAKAIAEAPKIDNAHHDISDKLYYVKSMLLYLEGTRCKVDNALADIEGRQRINNPITQYMRHQRDKQGFPQTILKVPSWAKDECLAFCTGGGSAGSTSPDWNDRGNGDGTSGQHETDFDEFSSQDSGCDHNTDSCGEESNKAPSNLISAPSIGKCRAIYDYDANLFDELTIRTGDVINIHDKQEDGWWLGELNGIIGIFPATYVEEVAATESNSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N964</accession>
    <name>A0A1D2N964_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integrator complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_04872</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N964"/>
    <dbReference type="STRING" id="48709.A0A1D2N964"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016180">
        <property type="term" value="P:snRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16291">
        <property type="entry name" value="INTS11-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000002">
        <property type="entry name" value="Integrator complex subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000028">
        <property type="entry name" value="Integrator complex subunit 11 isoform X3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041897">
        <property type="entry name" value="INTS11-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048662">
        <property type="entry name" value="IntS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF37">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21386">
        <property type="entry name" value="IntS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="12">
        <location>
            <begin position="30"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="13">
        <location>
            <begin position="259"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="775"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN01803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1129" mass="129389" checksum="4DDBD215F6088725" modified="2016-11-30" version="1" fragment="single">ADGSEENWYKSRVKMPEIKLTPLGAGQDVGRSCLLLSIGGKNVMLDTGMHMGFNDERKFPDFSFITNNMSLDDYLDCVIISHFHLDHVGALPFMTEMIGYKGPIYMTHPTKAICPILLEDMRKVMVERKGETNFFTSQMIKDCMKKVVSVNLHQTLMVDDELEIKAYYAGHVLGAAMFRIRVGQESVVYTGDYNMTPDRHLGAAWIDRCRPDLLITESTYATTIRDSKRCRERDFLKKVHDCVDRGGKVLIPVFALGRAQELCILLETYWERMNLKVPIYFAAGLTERATNYYKMFITWTNQKIKKTFVQRNMFDFNHIKPFDKQYIDNPGAMVVFATPGMLHAGLSLQIFKRWAPNENNMVIMPGYCVSGTVGQKILSGHKKVELETGQFVEVKMSVQYMSFSAHADAKGIMQLIHYCQPKNVLLVHGEGAKMEFLKQKINQEFKIDCFMPANGETCTITTKPDIPVEISLPLVKKEETEYDLQPPDPKRQRLLHGVMIMKDNKLKIVDVESAAKELNLPRHFMQFTETVNVRDLGTLSRVTDKIANLLKARLPDVTVDLPAENEVSVDDGRVIVKVGQIPKNDTAKEVSVTWSIDDDELGAFVFALMGTLNNNDFKWQCMSNATRRVNRESEQAQYIHLQPHHCIGWMNIQAVRIVMALTTGKVLHSAFGFARNSVKINYLQRELAFLQCPSQSCSLFLLQKSHFHYQNIIQIQIQTKHGILLDALQRSRVTAADLEELNLKIPDELRRLKAGSLKWIFDVWPLPKKSLSRLTNPQHFRQDEEDKKGKSKTKKPKSGSEEQLHRVLDFLKSKNVAIRRLVKLPWLLSADPVILEESAKRVQKLLRINNFQAAISFVNLNESKLRETASVWANEANLLSRENELIGETKVQFHNRLDFMAYYLKCSPEDVSDMMAKVPKLMTLPLMQIKNCILCLVEGGVKPDYIVSDPWVFVRNLDSMRARLEVINENGISDFKPWVLRSSQRIYELYISRETAEMQLLGDLKDIGSFLQQKLDCDKQTATTMLAKVPSIKKATAVKLNEMIEFLYSQGFSKQHIVETPRILAHSVDTMAERLEEVMEYKDPLENLQILCRTKKEYRAVIRKWKRGLEHDDNDEDENLNETASNTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9C2</accession>
    <name>A0A1D2N9C2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000136">
        <property type="protein sequence ID" value="ODN01863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9C2"/>
    <dbReference type="STRING" id="48709.A0A1D2N9C2"/>
    <dbReference type="OrthoDB" id="422700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.40:FF:000002">
        <property type="entry name" value="josephin-1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040053">
        <property type="entry name" value="JOSD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006155">
        <property type="entry name" value="Josephin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13291">
        <property type="entry name" value="JOSEPHIN 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13291:SF0">
        <property type="entry name" value="JOSEPHIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02099">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01246">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50957">
        <property type="entry name" value="JOSEPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Josephin" evidence="8">
        <location>
            <begin position="266"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="451"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="475"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="530" mass="57963" checksum="D91EA9D8D827980A" modified="2016-11-30" version="1" fragment="single">FFKPDVRDLETNSEWIVWTRKRDSVTDDDVVVAVAGLVSSTGRHNSRHISSLNAVVVGNLDLLPGKAGRVGSDTVFISAALSQSSTNTGKPYNQNRTKCKNGKAGVSTTAAVWRSRCSKGFAFFTGAFSVKSCVWSDELSSSSKLKRVRDKNEEDVKEDTQSEINQVRIIKNVNVVAALSDLQPEQLVVGSSENCLSLGTTKDRPVETKTGVIVATNSSAPTASSSTAPLENCRFDNSAVANVGDTSISSNCELLGTGTANSKIMRGGIYHEKQIKSLCALHALNNLIQDGKAFKQEDLDKICSELDPNSWVNPHKSVFGLGNYDINVIMTALQQKQLEAIWFDKRKDPSEELNFENIYGFILNIPSDCRLGWLALPIKRKHWVAIRNLPSITERDAGRNNYYNLDSKFDKPESIGTTDNLVEYLRGELKSPEKELFLVVTEDVGRVETWRKNPPPCTSATASGANANLLPVPTSSDGPDASAGSGNNRRTSNDSGVVDLLPDLKDINVVDLNKEDLMRRQSSGVWSDMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9Q4</accession>
    <name>A0A1D2N9Q4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000131">
        <property type="protein sequence ID" value="ODN01984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9Q4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN01984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="48" mass="5149" checksum="E7E93E6643CAABF4" modified="2016-11-30" version="1">MAHEGKFFLDGAFPTGSFALISSTFSVSKVCGKDESGCVKETKFSLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9V4</accession>
    <name>A0A1D2N9V4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000129">
        <property type="protein sequence ID" value="ODN02017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9V4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905268" description="CUB domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29686" checksum="1FFE087A8BF4020B" modified="2016-11-30" version="1">MKINCVTLLSTFLGVSLAQETATECGQTINSNQGAIEYKWHEPYEANELCVFIIRTQNVTGITITLFDHGISDSDPEAITILGFNETGLVVSTHVGPPEWFPTRSIDATHAVVIFKTNTSLGTGFRMTYIADRFPSETLLADDRVFNNATHNELTLPLETNYIRQPHTNILVMTDEAKLITDPDTALKLTVWENLYGCGDYLMIYKFDETNEASFVARLCGGNSNGDVFQTKGIFIVLFYKLTTGIKMAELNWEKVLTNETTFHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9W0</accession>
    <name>A0A1D2N9W0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000126">
        <property type="protein sequence ID" value="ODN02041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9W0"/>
    <dbReference type="STRING" id="48709.A0A1D2N9W0"/>
    <dbReference type="OMA" id="PANGEWE"/>
    <dbReference type="OrthoDB" id="152385at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="9275" checksum="91B20EDDB3DFBC45" modified="2016-11-30" version="1">MACLLISKVPPAHPLLHPTAITANSVRLQWKQGDNGGAPIQGFVLNYRPANGEWEEITLNKKLSTHVVEGLNCGRSYEFYLIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCU6</accession>
    <name>A0A1D2NCU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger and BTB domain-containing protein 7A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000087">
        <property type="protein sequence ID" value="ODN03083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCU6"/>
    <dbReference type="OrthoDB" id="10067323at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051481">
        <property type="entry name" value="BTB-POZ/Galectin-3-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410:SF23">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410">
        <property type="entry name" value="HL07962P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="206"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="372" mass="42521" checksum="79E38EEC9C484348" modified="2016-11-30" version="1">MSKLYLVDCEKFQLQLVNSRSRRSAAAKFVGRKKFQVFYNTKTDRLPSSHLDLWKATQAVMQENYEKNRDQMAAMFGQWITVFFTISGSNPSNLKVDVEGWYLQKLVANFGQPLKLDLSLTLGGWKADAEGSLTKTTISGNEYANQRGECRFKTVSDIAFPCNFQYNLTLEGRMTIEINPADNIVFGPSTDHLAILKGMYEEKAFCDFNILSENGTEIPCHRTVLSANSPTFARILVTDCMETKVNAYKLDLSEEGVDALLKYVYFRNLDDPLASCHIAFELMDIAHQYDFIGLEDAIKQIFLGKSYLWYSINVAVDIYLYTLKLQDEQLKSEIVKVIKMKIDELEDSEVFQLLREEENKTAIDLMELCDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND52</accession>
    <name>A0A1D2ND52_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KAT8 regulatory NSL complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2ND52"/>
    <dbReference type="OrthoDB" id="6415022at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044545">
        <property type="term" value="C:NSL complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026555">
        <property type="entry name" value="NSL3/Tex30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13136:SF16">
        <property type="entry name" value="KAT8 REGULATORY NSL COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13136">
        <property type="entry name" value="TESTIS DEVELOPMENT PROTEIN PRTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="862"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1293"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1351"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1433"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="877"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1363"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1442"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1460"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1481"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1512"/>
            <end position="1526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1541" mass="168124" checksum="3CA4B7FEF288B5F0" modified="2016-11-30" version="1">MASLESSKDGHKAPSISMDNIKPEPEHISPVLPVTPFHEKANYKKTSTGLSSQSHVATGGEKPRIKRPYNKKRTGDYEKPPPKKRGRKSKKELSMIDMKEEDVDMNLHQMSTKISRSKKSPSQQKINRKTSTVKPKKTSVTAMGPSVFDKKILAGPHLTMKQVLEYIITDHSYCVPPDPLPAVSSNHQMIRSILGPRNVSKPRALQMMTMDSCDRSPIVLSNFSRSRGQLNLPSTPPTSSKLENLLKRGDASPVGVSMNSMRFSHSRNTSECRDESDIEIDVESVEPEKRVPYDTKKAIDVMKECEKYVEFARSEDTGNDWESKILKTGWTKAQSGLFDKIVSALHAERLARLTYERIGDAEPVLRRASIDRTASRVRRILGEYLWDSKLTQWLHGVLTESLNYDYLAVYLDVLQTLKSRCPQLVSRMMTLSVSLPLQQAGREDELVNILTPFLEPRNESGVLQTDGENNNNEACDQFTTAHSGEHENAPQTSIAAAACSENDSEIYLPERSVVPQMQDVINKLNSAKHAEALKALLERQWDPFAPVLLHRMKKLAANPVFLLIAPSAIYPKHSLNRRLRQYHDMFRRIGKIVTVSSRHFDARNYTSASTYIERIMYIAKEKVRTIRSSYPDRPLYVVGWGSGSILAARLSNMVGPVDGIVALGFPLHSVKRMQEDLHKVFSGLKHPVLFVIGGLASNNSLTDMELFRRRLPCETSLVVVGSGNENLYLSRAHREKLLTTQSYVDKTIMDEIAYFVNLHSKHNQTSATITTNISMKSSFPDAQRDDGFGKRFQGMSRGRKRSISSTSFDVEPLKNEDRVVKPDGEKTEMQSPSTKMSLLKKEADLIPKSPVAPYDYDFDEPSFIPSNKSSNKRKAYSSRPIPSTASSPTISNSLTASKLLQQSPNVKRRMSKPSGPTQRVPMLAQQGQRNSTPSLDPPNDDPAGLLKYLNNKSSQEVPLNDIKQEPGVVAQSLPIVLRQPDVAYPPTDSRILGTTFYSKDAAVTTASSIVTKSGKKKSNSKSKSVRISKTSSTESPSIALAAAITDVSTPGSSGSTPTPASSLDMHKYVLQHKQMIKQLEQHRQDNPPPPPQTSQLFKLLSPGGDSDSISPVSSLPYAQEYVKLKLIGSQPVTPSDLVAGEARTAVISKQNLVTNMAIPMIRLSTSKPDEGAPKPIIMTAPSSSLLTNLSAGDSGERIFVRATDKGLVKLNPTEIKNLIAGSRGIQVVSGVSGLTTQTPLVVKSSQDSSEPVALPSSSSEPLTIAAVSSIAPNDTPSIELSALLPETAAPSLQGVPSLTSKQVPSNEVASATKRSDVPSTVINESSLTMVDESILATIIKPSVTVSNSVSSIVKPPEVPDSPAESTSVDTGCATDTSITHPSSSVLPSVSGNSAVAAGLAGSGQQLESKIESSTAAAVPASEVLSNTLESVASSLPVSNESATKDTQKLTEENLSKDDSNCTEDQVETEPEDTDDEMSGLCISSTFSMCPTSGERVDPPEAPSSEVSQQPTDPKKSSKSEKPDVYRSKLRPRRSTSSFDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDJ0</accession>
    <name>A0A1D2NDJ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neural proliferation differentiation and control protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000077">
        <property type="protein sequence ID" value="ODN03323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDJ0"/>
    <dbReference type="STRING" id="48709.A0A1D2NDJ0"/>
    <dbReference type="OMA" id="CETESGT"/>
    <dbReference type="OrthoDB" id="6270617at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009635">
        <property type="entry name" value="NPDC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23352:SF2">
        <property type="entry name" value="NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23352">
        <property type="entry name" value="NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06809">
        <property type="entry name" value="NPDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="133" mass="14268" checksum="BE405A6A15158D7E" modified="2016-11-30" version="1">MLSIHERIKAAADVDYPAYGVTGPSKDVTPSGGDRKLAQSAHMYHYQHQKQQMAALQKGAIQGDRQGSGGSDVESDDDNEDGDYTVYECPGLAPAGEMEVKNPLFQDEPTPATPQTSKGSEEEEAEAASPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDV5</accession>
    <name>A0A1D2NDV5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 22 member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03565</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDV5"/>
    <dbReference type="STRING" id="48709.A0A1D2NDV5"/>
    <dbReference type="OMA" id="FASELMP"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17317">
        <property type="entry name" value="MFS_SLC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="163"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="579" mass="64036" checksum="104EE618FDF632BE" modified="2016-11-30" version="1" fragment="single">ELQMEEKSSPGQLASDSKAFNEPVTAAFEVTNKNIELEPENVSGKNVPTLETGVEEKSSSVMPLSLNDTREGGQSSVQEMPNAKLVFEDILYIVGGSGFWQLKILLLASFSGCCTGIHHLIHTFIGDVPAHWCRIPTAPLYTYNEMKEMVIPKDDEHSSCFHYSYEVNVTGFVDVNRNVSLPCSDFDFNQSVMHSSIPTEFELVCDGTSLAPAIQSLYMLGIMVGSPTLGALADQLGRKKTILLSSVIFLVAGFLISLAPNVWTILVLRFILGLGAPGIYATSYVLAIEVVANEWRSKAGSYFNIPFAFGYVSIPLVGYYVREWRQLQFILCIPSIILLATWYYLPESPRWLISKGKMEEAEKVLREIAKMNGMIANIPSNFKSLLQLVHDGEQCHDTPEDSKNCLQRVWNFFDRYLQVFRSPTISLRLYLAINAGMEIPAYFLIPLLIDYGGRKPIFIGLLLTCGMCLITGGVLKQGDFLLVMVYMGKFASCIVYALIYLFASELMPTSIRTYAIGMASMVGRLGSTCAPVIVDVLGGEHSLSCYVFGSLVTVGGLLSFMLPETLDKRLPATMDDIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFS7</accession>
    <name>A0A1D2NFS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sex peptide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFS7"/>
    <dbReference type="STRING" id="48709.A0A1D2NFS7"/>
    <dbReference type="OMA" id="YAHIHPY"/>
    <dbReference type="OrthoDB" id="5864054at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019427">
        <property type="entry name" value="7TM_GPCR_serpentine_rcpt_Srw"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053219">
        <property type="entry name" value="GPCR_Dmsr-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273:SF4">
        <property type="entry name" value="AT19640P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273">
        <property type="entry name" value="MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10324">
        <property type="entry name" value="7TM_GPCR_Srw"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="72"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="409" mass="45000" checksum="011817F766749D7E" modified="2016-11-30" version="1">MGDEFGDYVSEFVNSTMTSLINDTLVENGPVVGATDPATLGYCGSGLKAFGDGYRGIHGYTSLVVCLFGCFANILNLIVLTRKEMINPTNAILTGLALADLLNMIEYMPYAVYMNYLTHRKTYGWALFVLTHSNFSQVCHTISIWLTVTLAVWRYIMVAMPLKSKTLCTMERSNKSGTPATTSAPVNATSTAAGQNGGAAEDKYIVNLSDLANDNPFLMTTNFWLYSVVIKIIPCIMLTVVSLRLINSLMEAKKRKDKLLAKRTGAANPAARNNNGVGGGHEPREQESGGSDRTTRMLLAVLLLFLITEFPQGLLGLLSGLLGDSFFKNCYIPLADLMDFFALLNSAINFILYCVMSKKFRETFVQVFHLNRLLKLRKQHRGANHHLISSPTTTRQLLSSSDAKEQTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFU8</accession>
    <name>A0A1D2NFU8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 13B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02542</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000054">
        <property type="protein sequence ID" value="ODN04129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NFU8"/>
    <dbReference type="OrthoDB" id="445152at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039782">
        <property type="entry name" value="VPS13B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12517:SF0">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12517">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2060"/>
            <end position="2082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2101"/>
            <end position="2130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2738"/>
            <end position="2762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2762" mass="309141" checksum="0175B39533B914A3" modified="2016-11-30" version="1">MFRLESYVTPIIRSYFSKYVKNTDMKDFEVSFWDGDANFSNLELNLDVLDRELQLPLTFASGHVQGLMIKVPWRSITSEPIVLNVKSMELVLNCRDPNSEKGKKKSQEIKRVEPATNTSAQTSGYVQMLIAKIINNVRVNFENVVIKYQESDISFSVNVGEASLTPADENWNHTFLHQILYAPDFVLRKKLSFSDVNICLDRCNNNGIVHRYHEPMMYRCDFDVRIIQKFATPNSRVPYFYRMDLFLGHLQFCVTNEQIPMLVRMYHLFTWLMQSGTTVDSMSEKEPDENEQNGELKTDKSSEESSKEIIPATEGESWASWATGLWYQLPEVFGDPEEPPDILDDEAGVGDADSISVSSPPKIEEILPAHGQREPSSSDEEELVTLVEVEPEQGVAASSPTKKVEDGFRPPCPATTHFGIYIKTLTIILRAVQRSCDRPSMRRNITISPDNKFLKCSIQGIVCNFILRGNENSHSFGVSSIMVHGLGFCPCGVQDCSSTEGGGSSQGGECYFEAGQIKQDFAASSLFPEESDGQPLTEWCYDVNHKDSLTSSAETALLEKTPAFFMKYVVIMKESTVIPATDNKPRSLLNAEILEIIYHGVAAPSKVLICSGLLHRLKMINEAINTYDYNPYDTQSALNLPDSRFGVSPNGPQCPVTTYRLVIRQPLIEILVADHPCDYGPEKRAEYFRKSGGIVKVTTTPRLKPEWPRMLISCDILELTAEDSDGHFDRLRRRVMGQYSLEEVRSRLKRIDAVREDELMKPGKSRESKTAMVYLSVKEVLVTFVSEPVELDVGIKSASFQLDFLNSHFYTPHDSVHRIQGGSYLETLTCSTRLEHRSNILWLPFTPKMTVSCDWEPSLRSPSIEAVIDITALFLYIGPETIITFSQLSEKLLVYLQEFLPSTAAQTSDVINEPKSVRRLKYNHAFKKESQKSWVLHGSSDHPDSPLAVDVCLKSNTVMWKFPQKRMLYGLTFHMQDVDRYDDVLSFEIEYYEQCTNSFYPYHKARVATDDIYEKGFYQNTRYCTAAEVWRITLHHPHGEVVLGTPPVECFTKSLFLESAVVPECNVTMKLPEVMINLVNNTHYAGRGIRNSVLQKYANTNTDIVSPSDHVIASLQCKLSLLCYSAIDDMSRLSANSRMSIKVLDYEQLVLDEVMDEVYLGAVITYTDNLLLGPPSAHIVTNEVNLKMGASLMHTLTYSTAMWNQIINSFDIKQCKMMPAEDRTKIILNRVLVCNELDLNIKLHFPYKEGIQPETVESNDCKAWCCPGRPLELANKYYFTLSDDPSTMFEIDIGKLGYTVLNSGMGSVFVNVLSLSESQRMIKISGPLVIANGLDKAIIMGLFTNHPYHPPEEQVLVPGKGTTPSLLWPENKYHRLSIRYLDYESEENEKVYLDNIIRNAEASNGVCSEVYRLPLNAPVKQGANQENPLPDWVQVYITLIIEYMQGSPRYLITVAPEYCIRSWLCNETLLHLGAEQDVEKDVFVAKGKGEINQIDLKGRKGLIPLFQTRYLQFQSNPDVPPSTKTVALSPAQKQVLVDPTTQVQPIDAIIAQITAQGSEGTLVNSSKPRWPFVSEEIDKCEWNTEINPETEILVCLSPWIEGLPTAVLNIRPWGLFVNLSGVELLFAQETAGDEWEQYWVPYKCVFSPKRIAVPSGKFRLGVMMNDFLVKSKPLEFSDQPERLSVKKINKDCKVPIECYSRLDLFGGSQLACLTIETRVQNGMLVVIVRPTYSIQNRTTFEVYAEGVTISSPVTQRRESWTDNKLSSYSILEASRDDPSTIDTAVPILHFVTDGQDYSVNTTYYKYLALSIGGPWWFVQLVDCTEVNREQKATDGIPGTKVAVTLPKVDCKILSPPLRHQLKNLSIASEAVVVGSYTQNGQVWISVSQDNAPQVYIHNKSTLPFFCVEKDGKKDIPHTSTTWFQQFLMVPPETSCQFSFQSAYHSFPQLNKREKPLPDMLMAFVSQDLIDLVTSNEVHGLTSVLDRPRQLLASSRNSKIPSGNLLFPEFEIEWKNVQSVQHYPTQLLSFGRKCVKLTVECVGYTYHVFIENTRLKQVSAKSIRSRVGDDNSKRHSKRGLLNVPNQTQGIFNHRLEGSLSRVPADIPSKQGSEAETEGESDGGPPTPPLMMVQKENKRKRSWIFKMYIPELYISLQDNFIVSSSHEREFLGLSFEALYLSQFPISEDSVLRPAECSTKESWVYGLRIGNFQIDTPRVSQEERLEFLVLVEPKKRIFINKNLIPTSAFSIPRFMETFERSPTLNLDCTLTLIRVSEDEINLDTAWLKVLPSSVFIEDRLLTYILPSVQRIGNVLNEGYGLVEQTNVTSTTGGVPNEITVDCGTITHLSITDDQSSGVVSSFYSDKELPFAGGSTKKTRSAAESSSLFSRNISFAPTVASSSSGLNSSSASMISSTMSNLRLASVSPPPPSPMVPLEPHGSSLKWPFDALCNSTKDDKNEDGGNEVLTTKRVKVPQELLHLFAQLSRPVRLSAIKIEPTEVELTLHTEKVVYVALDRSVVVLKGFQAYDSVTTDFHLGLELTMHYTMGTIFTIGNPVRVLGSLELLGSPGTLARTVGTGLRDLVVYPYEGFLTGPVGFVSGLGFGMSSFLQSVTSGSLQSITNWAASMSRNVDRWTLDKEEQAMIEGARLVELQGFRDGLVQGLSGCGIRLLGAIGGLSHHTIQNVVDGRPSTSGLLGGVGRGMFGVIVKPVGGFAELIAMTGQGILLATGWKPKPLAIKAKKKQSKSKEVDIEKGGASSDLESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFZ5</accession>
    <name>A0A1D2NFZ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000053">
        <property type="protein sequence ID" value="ODN04164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFZ5"/>
    <dbReference type="STRING" id="48709.A0A1D2NFZ5"/>
    <dbReference type="OrthoDB" id="6412801at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.30">
        <property type="entry name" value="Haemolymph juvenile hormone binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038602">
        <property type="entry name" value="Mite_allergen_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020234">
        <property type="entry name" value="Mite_allergen_group-7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038606">
        <property type="entry name" value="To_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008:SF13">
        <property type="entry name" value="FI04421P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008">
        <property type="entry name" value="PROTEIN TAKEOUT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16984">
        <property type="entry name" value="Grp7_allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905503" evidence="1">
        <location>
            <begin position="23"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="441" mass="49759" checksum="BD61B7F35821779C" modified="2016-11-30" version="1">MFSIRFLGSPFLLLILFSLTTCYKKDHGFGYLFKHDPNMKQREKAEKLTNDRIRGALSGMGSAGLFSDPFPIHDIQTKFSGANMYFTGARLYGLDRARPLQINADFTNLMVSLTLSMDQLNLLGNFKMTPWVAKAEGPFNFTIVDAWLTLEAELMFLNEGSDDEALSVSDILKTEFTYDELQLTLDNIGILNTILQPVKSSLAKFIVNQMKGTLCNEAELNFRNLMNQILPSLPKECPNAVNVVDRALIRARKSMKTSLLDPLLLPDDYPKTTKFIKLELIQGKLFGLSGIRRTGPILVGFERNAVHMLLNLGVENLRGQYVWTWTLWKNLLSHRGVLNFIVHDISIKVKLERRLGGSQENTTQVETIDMKVGSVKLLSDGIGAVKYIMETFLNVVPDSFRQKITDAAEYRILKVIEEKISQIDLEQLVEDETSGSMEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGC5</accession>
    <name>A0A1D2NGC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">F-box/WD repeat-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02503</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000053">
        <property type="protein sequence ID" value="ODN04155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGC5"/>
    <dbReference type="STRING" id="48709.A0A1D2NGC5"/>
    <dbReference type="OMA" id="AMVPWED"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22133">
        <property type="entry name" value="F-box_FBXW7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000133">
        <property type="entry name" value="F-box and WD repeat domain-containing 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000032">
        <property type="entry name" value="F-box/WD repeat-containing protein 7 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="133"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="286"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="326"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="366"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="406"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="446"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="489"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="598" mass="66716" checksum="28F5AF656CF3EF5B" modified="2016-11-30" version="1" fragment="single">MNPIEMTPETSVEKFSGLDGTIVDQTDQQLDSPEEECEDTRDDDGFELRHGSPYSYHADESLGEACSSVPSGASIRSIIPSKAHPPPRMGEWLQIFSGWSHPERLMAINELIGLCEATQVRHMMQIIEPQFQRDFISLLPKELALYVLSFLDPRDLLRAAQTCKYWRILADDNLLWREKCKEAGIGYFSAMSNRVHRRNRNSTNAHTPTASNSDVPNTRWKAAFMKQHYVEMNWKRKDTRDHKVLKGHDDHVITCLQFSGNRIVSGSDDNTLKVWSATTGKCLRTLLGHTGGVWSSQMSGTTIVSGSTDRTLRVWNAETGHCLHTLYGHTSTVRCMHLHGKKVVSGSRDATLRMWDVEIGECLHVLVGHMAAVRCVQYNGHLVVSGAYDYMVRIWDPEREECLHQLSGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGACKHTLMGHQSLTSGMELRDNLLVSGNADSTVKIWDISTGQCLLTLSGPNKHLSAVTCLQLINKFVITSSDDGTVKLWDIRTGEFVRNLVSLSSGGSGGVVWRIRASETKLVCAVGSRNGTEETKLLVLDFDTDVVKSESSVKVEIVKSTEIQLDFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGD0</accession>
    <name>A0A1D2NGD0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGD0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="14025" checksum="9B16349992BCA610" modified="2016-11-30" version="1">MDFTDRLIFDILIHIEMPTPFQNQGGGSYHIIPKTLEYITTFDGMCDRRFSSRNTTTGLPLLYQTVFLSLEEKILLEELHSFVLLLITQKQSNECYCYVLTPQSLIDIVITVDYRRRVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH28</accession>
    <name>A0A1D2NH28_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cleavage stimulation factor subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CF-1 77 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Cleavage stimulation factor 77 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_02407</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). CSTF3 directly interacts with CSTF1 and CSTF2. Interacts with FIP1L1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000049">
        <property type="protein sequence ID" value="ODN04266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH28"/>
    <dbReference type="STRING" id="48709.A0A1D2NH28"/>
    <dbReference type="OMA" id="PKRQYFK"/>
    <dbReference type="OrthoDB" id="26282at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000002">
        <property type="entry name" value="Cleavage stimulation factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:002655">
        <property type="entry name" value="Cleavage stimulation factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="12">
        <location>
            <begin position="36"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00055756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00062648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00076953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00078012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN04266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="584" mass="67675" checksum="70ED5443F5C23001" modified="2016-11-30" version="1">MPGCRDEYTPSMGTSVLKVALEGGGRTYLSYLNSSLDCWINSSVNQMKARNYDKVEKLFQRCLIKVLHIDLWRLYLQYIRDSKATLPTYKEKMAQSYDFALEKIGMDIQSFSIWNDYANFLKSVEAVGSYAENQKISAIRKVYQKAVMTPMVSVETLWKDYIAFEQGINPIIAEKMSMERSRDYMNARRVAKEHEAITRGLNRNFPSVPPVASPEELRQVGLWKKYISWEKSNPMRTEDLTLLAKRVMFAYEQCLLCLSHHPDIWYEAALYLENMAKLHSEKGDSNAAKTFNDEAAAMYERAISGVLCKNMLLYFAYCDFEEVRVKYEKVHSIYQKLLEVEDVDPTLAYVQYMKFARRAEGIKSARAIFKKAREDPRSKHHIYVAAALMEYYCSKDQNIAFRIFELGLKKFPDDVDYVMSYVEYLSHLNEENNTRVLFERVLTSGTLAAEKSVDIWNKFLEFESTIGDLSSIVKTEKRRSTVLNQLKEFEGKETAQIVDRYRFHDLFPCSPGELRSIGYSDVLAVSSKSKVELPIIAETPETEEEEEEKICRPDFSQMIPFKPKADAYSGEHVDHFLCHPRLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI33</accession>
    <name>A0A1D2NI33_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">5-hydroxytryptamine receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_01858</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI33"/>
    <dbReference type="STRING" id="48709.A0A1D2NI33"/>
    <dbReference type="OrthoDB" id="10034726at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004993">
        <property type="term" value="F:G protein-coupled serotonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071880">
        <property type="term" value="P:adenylate cyclase-activating adrenergic receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF199">
        <property type="entry name" value="IP13425P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="266"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN04862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="36762" checksum="3E40740BD1A77AED" modified="2016-11-30" version="1">MPSTVASVAAVLISTAAPFLLTFGTLVNYERMTALSTNKSSNNFSSWAAVPTSIFHLNYSASHHHLYLKRSAQSYYHHRHRRWNHDHDGSGDVEVETQAEDIETFDEARVAALATLGAEAGRGSSNEYITAHNKTFKSSIKTGNGGGSEPFKIPLQLPFFLENETLNGFISNNSTGNASVPEDNGKGGDETHKLGEFNLGHDVVIGRDPMTRHHVHEPITTSEPGTITDDKGNENVFYHPPRATINFTTIFLVLMFSILFLLTLIGNGLVCLSLTFVKKLRKPQNYLIASLALSDLFVALFVMPFAIVLEIYEGQWPFDKGLCDFWVSGKNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJG0</accession>
    <name>A0A1D2NJG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-aminoadipic semialdehyde synthase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000024">
        <property type="protein sequence ID" value="ODN05352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJG0"/>
    <dbReference type="STRING" id="48709.A0A1D2NJG0"/>
    <dbReference type="OMA" id="WNYKFTW"/>
    <dbReference type="OrthoDB" id="10059875at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004753">
        <property type="term" value="F:saccharopine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000008">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="128"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="436" mass="48800" checksum="C412395D67A48CDF" modified="2016-11-30" version="1">MKNICILGSGLVSSSVINFFYNDKAEEFRIVVGSKLHNELTSLQKKYPSIKTVGLDVTSKSDEGQLSEMIKDSDIVISLLTNEMHVPIAKKCISLGVNMVHASYCTNEMMELDEEARKNGVTILNEIGLDPGIDHFLAKRAIDEIHAESGSKVTAFISYCGGLPEPKVSSSNCLRYKFSWSPKTALGNLLNPAKYLERNEVFEIPAGGELINAITDMDFLTDLQLEGYPNRDSLIYKDLYAIREATDIIRGTLRYRGFGKVVKTLQKLQLLSSKPTEELYSENDNRSAPKSWSDLIFKILQNADMLETYYDKGEPITQLLVKCGFGLHEVNAMRDLGLLSQEPQLKLHEILIDTLADHLTTKLSFGENERDMVILRHEIRSQKANGDQEIREIEFIEYGEQDKGGFSVMSKTVGLSIGYATKLLLNGIISLSKKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJN5</accession>
    <name>A0A1D2NJN5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2,4-dienoyl-CoA reductase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJN5"/>
    <dbReference type="STRING" id="48709.A0A1D2NJN5"/>
    <dbReference type="OMA" id="GKAMTKY"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008670">
        <property type="term" value="F:2,4-dienoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05369">
        <property type="entry name" value="TER_DECR_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="307" mass="32731" checksum="3D8E96E9D71CAF42" modified="2016-11-30" version="1">MSDTKPHAKHFPIKKTPMLPKGTFSGRTALVTGGGTGLGKGMALMLGTLGASVAIMGRRQNVLEKTAAELASQSGSKILACSGDVRDPSAVKAAVDKIEKELGLPTLIVNNAAGNFISPTERLSPNAVKTIIDIVLGGTVNITMDIAKRLIAAQKSASFLSITTTYCYRGSGFVVPSASAKAGVENMMRSLASEWGRYGIRLNCLSPGPIWAEDSGAWGRLDPTGKFKKLALDKLPIGRCGDPHEIANLATYILSDYASFMTGETVLLDGGELCYGAGEFNFLTHVTNEQWDQMEKMIRDTNKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJQ2</accession>
    <name>A0A1D2NJQ2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_01210</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NJQ2"/>
    <dbReference type="OrthoDB" id="428525at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03685">
        <property type="entry name" value="ClC_6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048256">
        <property type="entry name" value="Tektin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF136">
        <property type="entry name" value="H(+)_CL(-) EXCHANGE TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03148">
        <property type="entry name" value="Tektin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="11 13" id="KW-0868">Chloride</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="16">
        <location>
            <begin position="774"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1235"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN05457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1402" mass="158112" checksum="DBA3A0BCFAC90B15" modified="2016-11-30" version="1">MTKASSMERKRKKENDDEPPEQEDEDAPLIRSDDKNQPKSYRATAATDVRRISGDFSINSSISDQDHGQPIMESSAILDDSVRSFGDGRSFESREGVLASSSMGPLHGGDRLECKKVEPGTLHLLSSKYESLDYDLCEHTLLIDEERTKGYRFIAKKDLLRWVIMIFIGIITALIACCIDIAIEEGCSAKFAFLKEKVDKCAAEECMVYPFLWWVLFNVVPVVIGSALVVYVEPVAAGSGIPQVKCYLNGVKVPRIVRIKTLIVKAVGVTCSVIGGLAVGKEGPMIHSGAVVAAGISQGKSTTFRRDFKIFKYFREDHEKRDFVSGGAAAGVAAAFGAPVGGVLFSLEEGASFWNQSLTWRIFFGSMISTFTLNVVLSTYHGRPGELTFAGLLNFGKFDNTSYDFRELPVFIVMGCLGGLSGALFNYLNFKLTVFRIRYITKKYVKVLETVVVAACTATVGMGMILYLNDCKPLGEDPTKYPIQMYCADGQYSTIGAIWFQTPEASVRSLFHDPPGSHQLTSILMFFTFYFFLSCWTYGLSVSSGLFIPSLLTGAAWGRVVGMGMEEMFPGQTWVDPGKYALIGAAAQLGGVVRMTISLTVILIEATGNLTLGLPLMVTLLTAKWVGDYFNEGIYDTHIRLMGVPILGWEPPPLSHNIYATEVMSCPVVTFNCVETVGKIADVLTNETYNGFPVVDVPLCQDGRNFGTFRGLILRSQLIVALQHKLYNETAESWNHKGFTIKYFRDAYPRYPTIQQVHVSDEERHFTVDLRPIMNPAPYTCLHNASLPRLFRLFRGLGLRHLVIVNDNNEVVGMVTRKDLARYRVEKHMGRMRLEELTILDHLYHSWATAIIDCIILLTMSEYHKGRLIEGINTWHCLQFQLLMKIFQPIQAQSFRNSVTTINETTLPVPADNAAFVQQMLSAVIFVVFFAVVFLGPPNASKQSMKSYRHDLPLRPVVCVGKMLGKITCRLEKPAERLSKSDWDNFTWNFANQAEQQREDTLRIRHEGRSIRNESGIQARWDTYKNNNRIRERITEIDNWRVTLEQTVSAVDKELNKLGAAKEAVEQAIETKVIDLDIVNEILSIRGQRRGKDNVIDEAQEELTKETCLLKDTRNILEKKGQEAWHQMARLQEVRQHILRDLNEKIISLDIDRYLLNLNESSSEIAFRPDPLRVPPGMMTPQAWEEQSRYNKLRADCELANSVKLREAMLLAIDQTYNDIRAQQEMTDFAMRKRLHELTKAANDLTHQRQKILQEMCKVEKEIRDLEDALMDKTNKMKLAETRLENRTYRFGVELTRDDAQYGLQQEVLQLRASVKAIQIKVNEAKKALNMLLGFLQQLEGEIENKNEVIVIEKQALDVRGRVAASADTPLTKTDRNIALSATVPVPEDRRKETGELGRACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK01</accession>
    <name>A0A1D2NK01_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01117</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK01"/>
    <dbReference type="STRING" id="48709.A0A1D2NK01"/>
    <dbReference type="OMA" id="WFANIIT"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="34089" checksum="E36C03BE3FE78784" modified="2016-11-30" version="1">MNITPVYENISTYTGLQNVHHTDHGDDWELQEPPQFEPLWFEKFDRRWWLTFAREHWYLSVCASMVYIIAIFGLQTFMRNRPAFELKKALFVWNAGLGIFSIIGFVRYVPEFMSVLSNGGVHNSLCRREGLNVPLAYWSLLFTLSKFVELGDTVFIVLRKRPLVFLQWYHHAITLNAVWLMVPYLEPISRWYAFMNYGVHSLMYPYFALKAIDVHISRKFANTITCTQLTQMVVGLLVNLYTIFVISAGGDCIRHPNSVKMFLTVYGSFTLLFGELLYKTMFAPSKKRSKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKN9</accession>
    <name>A0A1D2NKN9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Neuroligin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_00910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000016">
        <property type="protein sequence ID" value="ODN05811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKN9"/>
    <dbReference type="STRING" id="48709.A0A1D2NKN9"/>
    <dbReference type="OMA" id="HVANRTE"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905697" evidence="4">
        <location>
            <begin position="25"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="41"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN05811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17608" checksum="3AB9E52E5E0D5F03" modified="2016-11-30" version="1">MLIPVEILWIFLVLLIAQPQLLWSMEVDYSSPQQQQQQWSSRVVSTKFGLVRGLLFQKAGYEGVEVFLGLPYASAPVGSLRLMPPVSGSPWTGTKMNAEPAPVCPQVLPNIANETEALKRMPRGRLIQLKRLLPMLRNQSEDCLYLNVYVPTTGNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKW4</accession>
    <name>A0A1D2NKW4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amine oxidase</fullName>
            <ecNumber evidence="11">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_01083</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="11">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000020">
        <property type="protein sequence ID" value="ODN05606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKW4"/>
    <dbReference type="STRING" id="48709.A0A1D2NKW4"/>
    <dbReference type="OMA" id="MACIFER"/>
    <dbReference type="OrthoDB" id="8250332at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="13">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="14">
        <location>
            <begin position="134"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="12">
        <location>
            <begin position="271"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN05606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="693" mass="77642" checksum="0353855B9A94543B" modified="2016-11-30" version="1">MYVSLANEDESSATKLYLSNPGTTGFPESEITYHPLDPLTSSEIRLATFIIKAINGTSQWIYKSITLKEPPKAELLQSFLKNDDISVGAAGKVDRKAWVLLVDPQTYDSYEIVLNLNKITLESWKPSKKGAKPPIITSEDVVLAGDIALTNPDIARRIKATGYNLSQVVCDTWESGYVADNPNYATSKHLLQVYFYGAEFSGDNIYAHPLDFVAYVDTVTKTVRGIESLPVQNGSGKDQHIGNSIPRTSVNYFPYLRPPQTSSKMSVLHPIKITQPNGPSFDLHGHQLTWQNFVMRIGNNEREGVVLYHVKYNDNGNVRPLLYRMSLSEILVTYGDPTPPYHRKQSFDMGEFRLGFSSSDLAANNLCPGNAQYLDMVYHNERGESHRIENAICIYEEDSGVLWTHKDWTQGETATARSQRLSISFLATVGHSDYWISWRFYQDATIELKVKLTGVRNTNLMGSEVKAPAYGNIMSPQVFTSINQYFFAARIDADIDGVTNTVSVEDIVAMEDDLGSSTNPYGNGITTRETILETFANARTNVSPQKSRTWKIFNPTKKHPLTKGPTAWKLVPNGNYVPLLMKKNSPLRENTLWTDYNLWVTPHIDDQLYASGLWMDNDGLADWAKENLTAGVVQTDVVLYHTFGITNVPAVENWPVSSDKQETTGFILKPNFFFTENPAVNVPMSNKSTLDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLF9</accession>
    <name>A0A1D2NLF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pyridoxal-dependent decarboxylase domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_00632</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLF9"/>
    <dbReference type="STRING" id="48709.A0A1D2NLF9"/>
    <dbReference type="OMA" id="RLQYACR"/>
    <dbReference type="OrthoDB" id="2161780at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050477">
        <property type="entry name" value="GrpII_AminoAcid_Decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055103">
        <property type="entry name" value="PDXDC1-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055102">
        <property type="entry name" value="PDXDC1-like_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735:SF1">
        <property type="entry name" value="PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22930">
        <property type="entry name" value="PDXDC1-like_cen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22937">
        <property type="entry name" value="PDXDC1-like_cen2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDXDC1/PDXD2 second" evidence="7">
        <location>
            <begin position="477"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="PDXDC1-like third" evidence="8">
        <location>
            <begin position="656"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN06081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="821" mass="91717" checksum="07AD4FDBB812928F" modified="2016-11-30" version="1">MGDIMDGNDNRRNSVASVTTNPPIQSSTGVKEIQVTAKEIVDRISNFQHMPPVGLESIGVFDEKQAKPTGYVKPFTGGSEPSGSSSGDEKTDDTRSDKDAQPTTTPPPSTAGGTSQTEKPRRLSSKNSRLSVGSFTSEGGGSSTIEQRAIEHLLDVVQKIAQEAKPEDEIGIGDMSAISNMHWVYSVESYLRSLEIDWKNQKALTHKFATQLLGWIKQLFHFGPETNPEKEFNSIHPHWESNSGLTTIAKLSLHTKFPEIWAQGYQYFHESNKQPVIYCADDLVGQQICCSLGLPLTYTSIVNFTEPNWVEQFESKLKADIDKGKVPVAIFLNAAVENLEKGVKLAETFKVWTHFYGNNVTAYFLKRPETKQIGNSFTIDLTKWLKNPKLPYLTIYKAADRVDSNLMDILGLGSPKLEILCFTPWLIVHVFGKSRLSALINEAIHRGKFLLDMVRRHECLHVVPNWSKATDGNIILSTLTFQYNPPNYKRRNLTIDSPSSPNKVTDSYEPSAQYVDTLNSWLFHIMERDLKGLLSIEFVFVESRGWNIHVDVVKSQKLLPNEEAAIISVFDSHMKVLHATVKQRLRFLELVKVSEELEWVNDHGAHWAGLGAVRYIPKFFRKGKTSAPTSVNGVDGSASDAVVNGATNSVDEPPDHHTAEARANIDHLNAKIIDKLKAIDSAFSLGEAANGVWCVQFGMVTEDTDVKELVRLVIATGLEIEESSEFLDRMSELVRKGIEKATEELKKEAEEAMWEEGILRRVPVVGTFVSWFSPPTKESGVRGRALNLTQGKVESTENIYKYHMQIDASSIPNNMTKPIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLU6</accession>
    <name>A0A1D2NLU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">F-box/WD repeat-containing protein 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_00474</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLU6"/>
    <dbReference type="STRING" id="48709.A0A1D2NLU6"/>
    <dbReference type="OMA" id="GIAHVWS"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22183">
        <property type="entry name" value="F-box_FBXW1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000001">
        <property type="entry name" value="F-box/WD repeat-containing protein 11 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000004">
        <property type="entry name" value="F-box/WD repeat-containing protein 11 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021977">
        <property type="entry name" value="Beta-TrCP_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12125">
        <property type="entry name" value="Beta-TrCP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM01028">
        <property type="entry name" value="Beta-TrCP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <keyword evidence="2" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="domain" description="F-box" evidence="7">
        <location>
            <begin position="77"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="185"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="225"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="265"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="308"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="348"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="388"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="437"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="477"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN06221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="506" mass="58223" checksum="A0CDC4E98D905465" modified="2016-11-30" version="1">MDEMVEEPPRRELSSTYLTDKERNLATFDGWTEGEQLDFIENLLLRVCHYQHGQINEFLTPMLQRDFITLLPKKGLDHIAENILSYLDAKSLCAAELVCKEWNRVISDAMLWKKLIERKVRTDTLWRGLAERRGWIHHLFKPRPGSSHPDNSFYRSLYPRIIQDIQNIENNWLKGDPNLQLINCRSENSKGVYCLQYDDSKIVSGLRDNTIKIWDRQTLQCTKVLTGHTGSVLCLQYDEKVIISGSSDSTVRVWDVKTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMNSPTDINLHRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWNTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLKVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASSLCLRTLVKHTGRVFRLQFDEFQIVSSSHDDTILIWDFLNFDQPEALPSVPKTDNDDQPQQATSPHQWFPYQSMAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLW6</accession>
    <name>A0A1D2NLW6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Histone-lysine N-methyltransferase SUV39H2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_00488</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLW6"/>
    <dbReference type="STRING" id="48709.A0A1D2NLW6"/>
    <dbReference type="OrthoDB" id="1045173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046974">
        <property type="term" value="F:histone H3K9 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10542">
        <property type="entry name" value="SET_SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Chromo" evidence="12">
        <location>
            <begin position="383"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-SET" evidence="14">
        <location>
            <begin position="606"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="13">
        <location>
            <begin position="673"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="15">
        <location>
            <begin position="864"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="334"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN06241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="880" mass="99469" checksum="A86F384BDB727C16" modified="2016-11-30" version="1">MPTEITNVTQEVGNIFDFRMLNGVEEYYVEWKTDSKPAWVKEKIIINKCREKLAKFWVSVLLSSKTSPSVKAKVEGKLRDWSKAKIATLSQDSGIYEVVNGDFTTVASKKRPLQCSTDVSSEYNGLGVKHPKLISKFENLQSHLIPKSDIVNHILTERKSEPFRPYEFGEIINVEKDSISDKNRYYVSWHYESYETAETLGLKEDILHECIISRSHTSPEQSDEIRKSLQRKRSGKLHVVEPAVLILAEGRLSDSGSDLSTASTKPPIWELEPEKGDDISCVSSELTCHQVNNGDSELSKDDFGCQTDFHLDPFTCQYCQSKLGKVERLTSLRQRKKSEPQLTDPVVGSKSKKKDDIKNEKGVAENGNGEEIDEDDDLVEIEYEIEDILDYRKNVEKNNEEYYIKWKGFTAAYNSWEPESNLSNCDKALIDFYVKRVSQRKNWQTMYKLDLEDSGTNKKIPTIPAQPPLPEIIMEALNKITPVTDEEIEVAYQISKSTSKAKNSRWAQQKLRKCMLGLVGLSPYVVVHAEMPELRHQLLMSESERRKEVVLMDLKVWERSLNTIGQGRPEIVVENKYDLCGPPVDFKYINDNVLGSGVTFPDDPQEGCVCEDSCIKENTCCPTKHGYRLAYTSAKRLRVLPGYPIYECNKRCACGPDCANRVVQDGTLSLSGTKLCIFRTSNKRGWGVKTLKKIKKGTFVCLYAGEIITNEEAESRGQIYENQLGACYLFDLDYYTYSGEAGEEEEACPFTIDATKMGNVAHFINHSCDPNLSVFNVWADCVDQNLPKLAFFAMRDINRDEELTYDYGTHDAKPTSQPPAVEPVLSEAVMNGEDSEGSVDPDFTIITASSPAKNRMKPATISAVRRPCLCGAKTCRKVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMF9</accession>
    <name>A0A1D2NMF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">A disintegrin and metalloproteinase with thrombospondin motifs 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00243</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMF9"/>
    <dbReference type="STRING" id="48709.A0A1D2NMF9"/>
    <dbReference type="OMA" id="NGRRIDW"/>
    <dbReference type="OrthoDB" id="6497651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0401">Integrin</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905771" evidence="3">
        <location>
            <begin position="23"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="4">
        <location>
            <begin position="161"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="598" mass="67145" checksum="FC4CDE5EC54B321F" modified="2016-11-30" version="1">MKVVLAFPILLFFVVVHASVAAAEIGPQPQQIEHTITSDGKQYDLKLTKPDVSILHPNIQVIQIDLDNDGGYHTADSWAPSNAEIKEAEDVLVDEANLAAVRMNYENGERSFRGIIDGMRLEEENGIATLYTASLQNRSDYIDLGRNLTMPTTRDGGRVNAVVEVVVVCDKEWGDVFQHDRKKILDYWTLYFWDINLRFKTLPSNSISFRVNGIVVISSPSGQPFIEEARASDGRAEFNRILDRFASWIYGQMSTVPKFDMAIAVTNTRLEWGGGLAYMRATCWVDHAARRHWGTLVFSDGGDFGSLTVGSHEMAHTLGAPHDDDPNIPGGCQDRGYIMSGGNENLKWFFSTCSDRTISALVRSTDSACLRKIDELSSPQVNANFSSYPPPDMDEQCRRRLKNPTAYVEKADKGNCKSLKCWAKHEDGRMWLWTLGQELDNTPCTGGRCFRGRCRKEGKLIRNVATLECMRATNPFEFMAPLDLVDCPRPIIAGTPLDRFVLTDEPLGKTLATPWSSLDATENGDKCVYTGYIEGGGMWTDRCNVQNPWHGWDFIDVGNGEFMISHRITKRCAKPDGVNINTYSNCNKNDPTMRWRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNT7</accession>
    <name>A0A1D2NNT7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epidermal growth factor receptor kinase substrate 8-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00068</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NNT7"/>
    <dbReference type="STRING" id="48709.A0A1D2NNT7"/>
    <dbReference type="OMA" id="NIIMADV"/>
    <dbReference type="OrthoDB" id="4680325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035023">
        <property type="term" value="P:regulation of Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039801">
        <property type="entry name" value="EPS8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055093">
        <property type="entry name" value="EPS8_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041418">
        <property type="entry name" value="SAM_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12287:SF23">
        <property type="entry name" value="AROUSER, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12287">
        <property type="entry name" value="EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22975">
        <property type="entry name" value="EPS8_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18016">
        <property type="entry name" value="SAM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="207"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="394"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="511" mass="57620" checksum="A722A3487E397B76" modified="2016-11-30" version="1">MVSKKGKKKDHGEGLLSMRARPPHEREFVDILQKFKLSFNLLARLKTHIHDPNAPELVHFLFTPLALIVDASRDAHAAGLATRVVAPLLSRGAIELLNNCLTSKETELWHSLGDAWLLPREQWKGYVPQYQPVFMDGWSPTIPDSNNLGAAVASEAQRRMQERIIQAAQHEAEARRVDRERSISPVEIMPDDFASGQRAFVDSIRGRGGRVVMVTHPRTANNHKELTVVRGEYLEVLDDSKKWWKACNWKGQVAHVPHTIVSLLSEYPQEAGAYHGDRSALEDEMMQMELKNVLTIYREKRHIAIPRTPEVYIVQNSTPTEVQEWLKVKGFSTRIQKQLAGLNGGELFKLNRSQLEEYCGKEEGLRLNSQITISRNTSGYKTARSSELRAILAKARAKAEQPNGSFASTSMGASNSDHGVSRSASDASSKSPSPEKSSSKTVKVPVLKTTFKEENKNRKSRYDEDSEDDIVTRHFNFSDDGDDDSDEDDANKGTLGRMLKQKRREMLQQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0I7</accession>
    <name>A0A1D2M0I7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008821">
        <property type="protein sequence ID" value="ODM68289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0I7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM68289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="44" mass="4884" checksum="739B39C52215E874" modified="2016-11-30" version="1" fragment="single">MIDSTGISQSYTFEDTTPDFVVLYGTVAVVLFRLMEPGILMDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1L1</accession>
    <name>A0A1D2M1L1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposon Tf2-11 polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006987">
        <property type="protein sequence ID" value="ODM86850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1L1"/>
    <dbReference type="STRING" id="48709.A0A1D2M1L1"/>
    <dbReference type="OrthoDB" id="116216at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="274" mass="30717" checksum="9EF6835B2CEFF8DB" modified="2016-11-30" version="1" fragment="single">MSKLSPFRATATNSINALLKYIIYRHGTPKTILADHGSHLPPPIPQCEWLCEKNNDTIKRTLAKLLHDHGGDWEAQLHPAVFAHNTSIHSVTKHSPFFLVHGREARLSCDNTFPTYPIIETPEGPITRSKAAELANSSAKDNTIKFQAHQSQKYNDTHPTTSFSPGDLVLHSRLESTPEKTYDPYRRQQDKIIAANARLLKKYIPPDTSVSLPSQPDPEPNSIVITHTSVPESQSHFQTTNPNHTSISPLSFRDLMSLEFSTAEQATWKKSRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M216</accession>
    <name>A0A1D2M216_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transmembrane protease serine 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19702</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006542">
        <property type="protein sequence ID" value="ODM86982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M216"/>
    <dbReference type="STRING" id="48709.A0A1D2M216"/>
    <dbReference type="OrthoDB" id="6437225at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF140">
        <property type="entry name" value="BCDNA.GH08420-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM86982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="22258" checksum="EEA9A7650974A1A1" modified="2016-11-30" version="1" fragment="single">HRAIRGRDLRASGRPRPDVEVRLTRSADAPSGDNVHPPQPQLADAGQRHSFAKAPRKRSTERGSVPSVPPIRNHMSEMPGKRCTVTGYGYMGESGPIPLRIREASLPIVSEDECVSKVNAVTEKVFALPMSSFCAGGELRNDACQGDGGGPLVCRADDPNTGDSGTGYYELTGLVSWGFGCGRENVPGVYVKVSSFIGWIHQIIRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2F0</accession>
    <name>A0A1D2M2F0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase/endoribonuclease IRE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006188">
        <property type="protein sequence ID" value="ODM87091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2F0"/>
    <dbReference type="STRING" id="48709.A0A1D2M2F0"/>
    <dbReference type="OrthoDB" id="63989at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="269"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="58962" checksum="09103C04F5B15622" modified="2016-11-30" version="1" fragment="single">TTLLRLIGKGTNTFVFKGTFERRKVAIKKIFCESDEDIEKRLNEVKLLWECDSHDNIVKYHRKERDSDFIYIALELCDGNLQQWMESEIPNVNHDAISAIEILHQTTKGLAHSHSKGIIHRDLKPHDILLTRLNQREIRVKIADFGISRVLPEGRLSITIRTGSGTVGWRSPEILNYSSKASNHVDKMHFSVLLVGNFWLIQAMIARDPKARPSAENVSHFADQLLKRFNASIQPRSLQVDAQNLLNHSFQPPSLRNENQNLSNTSIQFPNLQNESQNLLNPSIQSSSTQNEGRNSRSIRKHTSNKVRHLKTTSRGTMSRDFGALARWQNIYHPKSAISSINCFIRREWVAHLCKMKVVHRDLKPENIFLRAVNHGVVVKIADFGISRTLPRNRSKLTVKTGTGTFGWKAPEILRTRNATIVCRMASCAYLRPSSYHLCIEFNSFGFSIFQSTATDIFSLGCVFYYVLSDKKHPFGDDEDDWENNINNYQKKIDERNKFLNFLCLKFKAELKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2G5</accession>
    <name>A0A1D2M2G5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDZ domain-containing protein GIPC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GIPC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006021">
        <property type="protein sequence ID" value="ODM87158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2G5"/>
    <dbReference type="STRING" id="48709.A0A1D2M2G5"/>
    <dbReference type="OrthoDB" id="6509831at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000097">
        <property type="entry name" value="PDZ domain-containing protein GIPC1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055349">
        <property type="entry name" value="GH2_GIPC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056814">
        <property type="entry name" value="GIPC1-3_GH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017379">
        <property type="entry name" value="GIPC1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12259:SF1">
        <property type="entry name" value="GH21964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12259">
        <property type="entry name" value="RGS-GAIP INTERACTING PROTEIN GIPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25083">
        <property type="entry name" value="GIPC1_GH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25082">
        <property type="entry name" value="GIPC1_GH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="93"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="266" mass="30276" checksum="E7B3795C419703FB" modified="2016-11-30" version="1">MGEMSRNAGIELEELRTVSPRKQAYHCQQAHGGITGLISGFSDMKELFQKIADYYDFPVEEILFCTRNTHRLIDSELYFDDFIFVHRKGVRKEVELTKVEGVLGLTLTDNGNGYTFIKGIQKRSLVDQSKQIQIGDHIEKINDKSLVGLGHAEVVNYIKSIPTGNKLVMHLVEPLKTVSRTLNSYTNNRLYIHDNNHFLNPFTANKLYEITLGKKNPNELAAAVDSCELEYFGFTDDFLIELWGIVSDAKEGDLLLLVQDRTMQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2X9</accession>
    <name>A0A1D2M2X9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Extracellular exo-alpha-(1-&gt;5)-L-arabinofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19354</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005555">
        <property type="protein sequence ID" value="ODM87328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2X9"/>
    <dbReference type="SMR" id="A0A1D2M2X9"/>
    <dbReference type="STRING" id="48709.A0A1D2M2X9"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903413" evidence="5">
        <location>
            <begin position="24"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="651" mass="73311" checksum="29D78F8749D1832A" modified="2016-11-30" version="1">MDPSRNFLRFLFICIALACSSSAQETFTNPIVDGNSADPFVGRVGDFYYMILSTDTEHELTIYKSSEMTNFRNVESKVIFRAPEGYQNVWASEMHRMMDGNLYIYFAMGPVGDFNRNWAIKADDPNDPMGSWSEAMRLLPHLEQPGVDGTILKHNSKWYYVWSGRDGIEGSLPHDSILITEMLDPVNTTTQTTVIRQPLLPWERNVNEGPFFIYNNNVSYLLFAASFTFSEYYCLGLMSIDEGLDPMNASNWWYGPEDGPVFYKNEEEDVWGPGHASFTVSPDGTETWAIYHASDDKDRIEHYRVARADKVEWGSDGRPVFPRPHGYYSPQPIPSGQTTITSKTTFTNPIISGDSPDPHVLLLNGIYYLPLTTDSGSSITIFSSSQLTNFRNVVSKKVHEPTDCISDIWAPELTVIKDELFMFLSLTNCTDNAHNVYVMKAENASDPLGVWDTPYRLLPEVTAQTADGAVLQRNGELYYVYESREDPYGLWIARMFNARKVDDTSRTLLKAPTESWEAGVTNGPAFLQRGNVTFMTYSAGNPGGADYSIGLMSIPDSLDPLVASNWNVKSDGPVFYRNDEDMVFATGHAGFTTSPDGSEVWMTYHAAEWPDRVFGNRVARAEKIEWDQEGNPIFPRPHGYFSPQPLPKGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3K6</accession>
    <name>A0A1D2M3K6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_19144</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005099">
        <property type="protein sequence ID" value="ODM87536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3K6"/>
    <dbReference type="STRING" id="48709.A0A1D2M3K6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000016">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="66"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM87536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="18860" checksum="EAA4170603989B41" modified="2016-11-30" version="1">MDRTKQTARKSTGGKAPRKQLATKAAPSFTPLVQLKVFYSHQVNQLLNMPPKASGKAAKKAGKAQKNISKGDGKKRKHKRKESYAIYIYKVLKQVHPDTGVSSKAMSIMNSFVNDIFERIAAEASRLAHYNKRTTITSREIQTAVRLLLPGVGKNTPSEGTKAVTKYTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3K7</accession>
    <name>A0A1D2M3K7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005073">
        <property type="protein sequence ID" value="ODM87558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3K7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11412" checksum="0225C09ECD7D409A" modified="2016-11-30" version="1" fragment="single">MATTKWIEYRVISAKFSCSRVDEVRFWILGQYDDYSKACQKLAKSLNTSTLESESDSIIRKRARRRSQKRKPAAASQSSSSDNSDSESSGDNETGHPKISGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3V2</accession>
    <name>A0A1D2M3V2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-mannosidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19024</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004895">
        <property type="protein sequence ID" value="ODM87658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3V2"/>
    <dbReference type="STRING" id="48709.A0A1D2M3V2"/>
    <dbReference type="OMA" id="YIENEIW"/>
    <dbReference type="OrthoDB" id="10261055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050843">
        <property type="entry name" value="Glycosyl_Hydrlase_38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607:SF70">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Glycoside hydrolase family 38 N-terminal" evidence="3">
        <location>
            <begin position="11"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 38 C-terminal" evidence="4">
        <location>
            <begin position="297"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="527" mass="60244" checksum="D9617AB4DD2C97F2" modified="2016-11-30" version="1">MRNENEEHLQYMTPVSSQNILQLADELMGQYRRTASLTRHNVVITGVGDDFQFNEPLEWDQQYNNYDKLFQFINANPQRYNARVQFGTILRYFKAVKDSHVELPTFQGDFFPYIVVKQSELRKAEILFTFTLNHLRQQNYSSEAQTLSLKIQLPGASQKMGSPFSTPHNTYGEALQILQTSSFEVFLLTETTKKVVFFNSLGWTKSHLVRILVETPFINPKLGTTENGDSGIFDGYYELVFVAYLQPLALTTYEIQREEDRKRVTQPNHNVAVSASVQCRNCGYNINSVDQQSYITMENDEIAAYFDSKEGLLKGITRKAEQLTTKVNLTYGKYDTSFGSGAYLLRPHINSKTNLLANCRNESGAQLYVVAGPVMQEVTVLCKDLTISAHIMLQGYPEALSAVYLTNSVKPQHSGTKFGEFFMSFQTDLETREKSFNDDSLEATFFTDTGLAVEKRMKVSRLPYEGNMYPVTNYAFIQDEQAEKRFSILVDRSHGFTSTGSGQLEAIFDRRLPYDDARYLRNKTNME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M406</accession>
    <name>A0A1D2M406_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA polymerase eta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_19020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004891">
        <property type="protein sequence ID" value="ODM87662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M406"/>
    <dbReference type="STRING" id="48709.A0A1D2M406"/>
    <dbReference type="OMA" id="WFTRSDA"/>
    <dbReference type="OrthoDB" id="447129at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009314">
        <property type="term" value="P:response to radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052230">
        <property type="entry name" value="DNA_polymerase_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21704">
        <property type="entry name" value="POLH-Rev1_HhH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036603">
        <property type="entry name" value="DPol_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="8">
        <location>
            <begin position="17"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM87662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="445" mass="50016" checksum="52E4850053E4ECB0" modified="2016-11-30" version="1">MASSMDFNRGGSTCKVITLIDMDSFECQVWERMFPAEEYWGRPCIVTDQTGRIVSASSEARALGISRSIRLGKAERLARRAGVDLKVFTKPNDREKPDGKTVRYASWELVDALKEYCEMYTFGTIMEYSSCDEFYLDITEEVTLRMALQDGDPVLIESRTFLEGKHEKISGDKLKYRINGLYPLKDDNTDDGLLEEERLVYGGLIMQDINNFLFRKTKFKASVGIGTNKLVAKLACGINKPNGITMFPSCALARLSKEISISSIQGLGGKFGSQLQEIFAIQKMSQLAALTFDDLEAVFDTEKALLAYMKSHGQCDEPVSAKLQNEGVSCGKNFFGQITSDETLKYHLHCLSQEMIERLEEEQSRHRRVTKFIRIQFTYSMKEEGSPSKESSLNGSSNFPNAGNLDATQLCDKALSAMFRDIKCSISSVNITRLCFTAGRFENIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4G1</accession>
    <name>A0A1D2M4G1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004517">
        <property type="protein sequence ID" value="ODM87867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4G1"/>
    <dbReference type="STRING" id="48709.A0A1D2M4G1"/>
    <dbReference type="OrthoDB" id="2448307at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39299">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39299:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="36331" checksum="7A071D6E9CB8941B" modified="2016-11-30" version="1">MDRKKAKEWGSDLIRTRISRETYTIEERTWRDFKFWEWIFIAFALLSISISIGFCVFQLVIAIIDKEKYIFPVLVILNNIFSAYFLWNGVMEELPFKLLMQLVVKIIIWIFDLIYFLVPSKEAGEGEEPDPYKEIRDIRFYISSSMLFLTLITGTVVIYQYWTSNIAIFRTVGTEPKYVRMCKMWNFCQSMMLFDAVVFITVVFHLCNFPEFVQSYASFYLIPSWLIATVVYVLLGIKAGSLGLLLYISLFFTAGMSFLAHIALLISVVRVQLSYGMGLKQAVNQGNPLLSQGQVYINSLTKDILIFENGDGNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4H9</accession>
    <name>A0A1D2M4H9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004473">
        <property type="protein sequence ID" value="ODM87887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4H9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="195" mass="22039" checksum="5D9C83C35BE4BFCF" modified="2016-11-30" version="1">MQAPTSNGCQERRSLPVVVGRQNAAKCIWSAMVASFTSAGVPLKIFRNPEVRKWIEANVKTGDTLPSETTLRKLLTQEEARISKKRRKCVATKASLRRGVSTSQLICLKSDNAKYMLTAGKTLKGLSSRMIHSTCWSHMLHLAPSRREELFRCLEAKGYRRKLPPTPVITRWCTWLEQIFFTISTLMPNGMASRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4X1</accession>
    <name>A0A1D2M4X1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor A domain-containing protein 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004207">
        <property type="protein sequence ID" value="ODM88037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4X1"/>
    <dbReference type="STRING" id="48709.A0A1D2M4X1"/>
    <dbReference type="OMA" id="YANDNEK"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="26124" checksum="88AF63416C083080" modified="2016-11-30" version="1">MPRSGAFTQVGSELVSLRNTALYPTSKLDDQKFEFIFMLDISGSMYDEPIQLAKEALLLFLQSMPADCYFNVITFQSYFKCFFPNSVKYSQETLEYAKQRVNALKAGGLTELYKPLSHVYSQPRISGYLTQIFTITDGRVDDRDTVLELVKANVQHSRSFSLGIGDEVDRELVIGIAENAGGTYEFVTYGEKIESKILNQLKVSLQPGLLRPIRVNTESILIPMYKNIEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M578</accession>
    <name>A0A1D2M578_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004153">
        <property type="protein sequence ID" value="ODM88074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M578"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="24642" checksum="DD0FEE7E480DC7AE" modified="2016-11-30" version="1">MSYEQLRPETLKMAQRNLKTAELFNGSSISLGQPCVNAIYPDNATGIWSYSLTPPPHCTLENNEICAPRPLSQFEEPDDPLRGGISVLKPKWVFRTDSAHGECKGHRTWVIQQFACRCGFRTDCGADLETKISCPLQPKDWEDRRQCLGSVGYPCETLPLAPGKHHESCVTEYCDKEENSCEDRPSFLRRRSGAMASPYGSLALAYPFWMMSLMILMIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5C6</accession>
    <name>A0A1D2M5C6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003985">
        <property type="protein sequence ID" value="ODM88190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5C6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="87" mass="9588" checksum="F1145A02829332F9" modified="2016-11-30" version="1">MFLIPLGQKLCVGQKNCTKSRIAPPIHNEELLIAFKKSGGKLGGYYSSLLLSLQFDAKTFGKCFCITSSVFFSWDFLGCATLSELDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5U4</accession>
    <name>A0A1D2M5U4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003833">
        <property type="protein sequence ID" value="ODM88284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5U4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="154" mass="17653" checksum="9524410A3811B758" modified="2016-11-30" version="1" fragment="single">MQIWFVKDGSEHIIWSTKTAGGIQHSRTILFDTTYEKFKRALIKSTNVGNPDPSMLHKIEEALNSSRNRSFIELRATYDDKTGICKIWTKMTFDDDLLKIWSKMMTEPKIIVQSAFLDGKVPISAAIPIFKGKSINNSESLVQSFTQKEYVPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M626</accession>
    <name>A0A1D2M626_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cleavage and polyadenylation specificity factor subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_18242</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003605">
        <property type="protein sequence ID" value="ODM88437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M626"/>
    <dbReference type="STRING" id="48709.A0A1D2M626"/>
    <dbReference type="OMA" id="TRSVECE"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000001">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-Casp" evidence="6">
        <location>
            <begin position="188"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="7">
        <location>
            <begin position="418"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM88437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="560" mass="63903" checksum="131FDF2455340B12" modified="2016-11-30" version="1">MHFHLDHAGALPWFLLKTAFKGRCFMTHATKAIYRWLLADYIKVSNISTDHILYTEADLEASMDKIETINFHEEKEIKGVKFWAYHAGHVLGAAMFMIEIAGEDRHLMAAEVPSMRPDVMIVVSFFFGIWFETRNDELKNVLLVLGVDVWNAHPREAEDRETRFTSIVHDIVGRGGRCLIPVFALGRAQELLLILDEYWALHPELHDIPIYYASSLAKKCMSVYQTYVNFMNERIRRQIAVSNPFVFKHISNLKSIDHFDDVGPCVVMASPGMMQSGLSRELFEMWCTDPKNGVIIAGYVVEGTLAKQILSEPEEVTLLSGAKVPLKMSVDYISFSAHTDYEQTSEFIRTLRPPHIVLVHGEQNEMGRLKAALIREYEDEGKHIDVYNPKNTQAVELRFKGEKMAKVMGALAVEKPVNGKRISGILVKRNFNYHIVAPQDLSKYTDLNMSVVTQRQLICYTTFAKEVEVVESKGNDKRVIRVFGVIDVVYEKGLVTVAWVASPVNDMFADAALTAILQADSIEVHPNDFPPPPDTDRDHFKVCFIMRFMRDEIYERFHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7T7</accession>
    <name>A0A1D2M7T7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch repeat protein M-T8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002961">
        <property type="protein sequence ID" value="ODM89033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7T7"/>
    <dbReference type="OrthoDB" id="5863680at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="157"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="330" mass="37429" checksum="67533F0F9521E0ED" modified="2016-11-30" version="1">MTWIALVEFTHDIIEESKGTNCYKIDLKDNVFPQWYEDDKAEVLNYCQKLTNILTRKYAMEGKGALTLHFNWEPSPPAKLQLKLQGPLLKTLVEICGKDIALQILLNDPNHSDWELDIFSGSLKIMLPSANEAFCEYQHAEASSAVVCKTVQENIQKDVTILANSANGQGQEVLLANKVFLMAHSPVLKSLFEGNFSESKKNEIKMKYSLECVQALLDYMFTVSFEAAVKSSRLAVELFQAAHYYQIQHLENKLVEMFLERRSSWFEADAAIELFKAATQIELHSSAELKKKAFEILKSKGNLRESAEFGKLFAENPNIALEFTLMALEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M839</accession>
    <name>A0A1D2M839_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein lin-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002911">
        <property type="protein sequence ID" value="ODM89102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M839"/>
    <dbReference type="OrthoDB" id="2339771at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045831">
        <property type="entry name" value="LIN9_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19438">
        <property type="entry name" value="LIN9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LIN-9 C-terminal" evidence="1">
        <location>
            <begin position="24"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="15818" checksum="03BD55C5E5944D8C" modified="2016-11-30" version="1">MAGVQAYCVEIPSDSQHSTATAGATNAQASKMINSEQVLERCRQDASMMVSNFNDNKTAPGGPGVKNPKILELIRNAATMMLGIRANSVTDKSPFEVKPIQEFFKNTVKANVEGKNLRLYEDRVEMVMNRMIAGLCVKKDSDMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8P2</accession>
    <name>A0A1D2M8P2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002706">
        <property type="protein sequence ID" value="ODM89353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8P2"/>
    <dbReference type="STRING" id="48709.A0A1D2M8P2"/>
    <dbReference type="OrthoDB" id="5953636at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016768">
        <property type="term" value="F:spermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015576">
        <property type="entry name" value="Spermine_synthase_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315:SF1">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12683" checksum="D0C52AD0264E0E88" modified="2016-11-30" version="1">MTYMKKWKAEGKTFDYVISDLTDIPLSKKPEDGLWDFIVKIINMSFSLLSPNGKYLTHATGSSNDNALNVFENVLETQLDFRVTFTKTNVFVPSFLEDWVFYQIQLKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8W2</accession>
    <name>A0A1D2M8W2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002688">
        <property type="protein sequence ID" value="ODM89379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8W2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="15598" checksum="18CE2ADE4AC6985E" modified="2016-11-30" version="1">MMMESTINVWKSLKRNWNVVIKVSKSVHADPKEIVCNELTSRSTRIADMRFVGRTPAEPLQMRSNTVACFVKNASIPIVSSVLIKLFEISDPPWFEKAFVFCSECSRQLTVVYELEKVMKEVERRLKESEKVVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9J5</accession>
    <name>A0A1D2M9J5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_17027</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01002475">
        <property type="protein sequence ID" value="ODM89657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9J5"/>
    <dbReference type="STRING" id="48709.A0A1D2M9J5"/>
    <dbReference type="OrthoDB" id="285308at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM89657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="310" mass="35258" checksum="7CAB83E5EF825BFB" modified="2016-11-30" version="1">MPFWKADCSESVEEALARLDLESKRNKAEKLAKLEAEKAAKAQINMTGTGNSKEEACYGDPLSLESDKERELSLNEKARKLYPERGGDPYKPSWFNVLIKGEGREGLDKMKCEMKVWKVVQQSYLVRLLMDALKSSGCEIDIRRHISCEVCDVSVTGGYDPTLNQVVICQNTARYKGIIQGALTHELIHMFDNCRHKLDFKNIQHLACTEIRAANLAHCSYMSGLTDGSLSFGSVKEQHQECVKERAVRSVLAVRDVSHEEARDVVDSVFEKCYNDLEPIGRRIRRNSDHMQKAYWERKSMGYDLSNKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9M9</accession>
    <name>A0A1D2M9M9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative cytochrome P450 6a19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_16995</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002443">
        <property type="protein sequence ID" value="ODM89687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9M9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF100">
        <property type="entry name" value="CYTOCHROME P450 6A16, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM89687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10955" checksum="321A0E1856B4FC89" modified="2016-11-30" version="1">MRKIEKALILEEDLHLDAGSQVMIFVQGLHKNPKYFPNPEKFIPERFSDEETKARILTLYSICWRSEKCWLQVCNVGGYNFERKTASSLCLGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9T9</accession>
    <name>A0A1D2M9T9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">m7GpppX diphosphatase</fullName>
            <ecNumber evidence="5">3.6.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">DCS-1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Decapping scavenger enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Hint-related 7meGMP-directed hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Histidine triad nucleotide-binding protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Histidine triad protein member 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Scavenger mRNA-decapping enzyme DcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_16989</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GMP + a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65388"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58285"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="EC" id="3.6.1.59"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HIT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.59" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01002439">
        <property type="protein sequence ID" value="ODM89692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9T9"/>
    <dbReference type="STRING" id="48709.A0A1D2M9T9"/>
    <dbReference type="OrthoDB" id="10264956at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140932">
        <property type="term" value="F:5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.40:FF:000001">
        <property type="entry name" value="m7GpppX diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000006">
        <property type="entry name" value="m7GpppX diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.40">
        <property type="entry name" value="Scavenger mRNA decapping enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008594">
        <property type="entry name" value="DcpS/DCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011145">
        <property type="entry name" value="Scavenger_mRNA_decap_enz_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019193">
        <property type="entry name" value="UBQ-conj_enz_E2-bd_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978">
        <property type="entry name" value="HISTIDINE TRIAD HIT PROTEIN MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12978:SF0">
        <property type="entry name" value="M7GPPPX DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05652">
        <property type="entry name" value="DcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09814">
        <property type="entry name" value="HECT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102860">
        <property type="entry name" value="mRNA decapping enzyme DcpS N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="22">
        <location>
            <position position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00030830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00032946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODM89692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="794" mass="89442" checksum="D9A1210A5E03327A" modified="2016-11-30" version="1" fragment="single">MDLSMPSKRSSSSVDDDTVFPAKKSSLDGKEERNGSSVSNNKAGVDGDGKQQQIFKDLSGFTLKNVLSNSADVKRLTVEGTFPDGQTAVVVLDKKPFTEENFKELFSSGSRLKQIFQNDIYGNYDCVPGEKSAAIKATIVYPATQKHVEKYMHHDLFLVDETPGLYEKVTLPHLEGSQFNIQWVFNILEHKKEEDRIVFEDPDPSTGFILLPDLKWDGSTLGNLYLCAIVHAKEIKSLRDLNADHLPLLKNIFEQGTAAIKKKYGLTRSQLRIYLHYQPSYYHLHVHFTSLNFNAPGIYTEKSHLLQTVISNIEGKSSYYQDATLPFVVKKNDSFWQTMAMSSEKSSLSSSSDTKSIKVFAEYLHNLRAVNLYVFVPNYVLDDSRVAVVSVYSNKIELILSDECTCKLILEGLLLQDCCKLPPRTLSKGVLCYRLVVKPESGYGSTGAEVVSNFEKTVDEGAKNLVKNSINTVALKEGTLYRIKCRFCSNFLSESVKFDRIRPLPSNNWVENAHELWFCHPPETGHAPVLHQDVSARLDKINLSKGGDEDQSSSSDASKTIVELLKCPDKNYCFYGPCNWAINKDIANGVQKNTSFTDNPIPRADCLHCNNEIGSFTSEFCVKIWDYGVEWVDQAQLLTNTEGIQKEPSNSATSRLAQNFKSIAFATIYELSDHPTFRFTVTSTCKGNSLFLWNIDRNLSVYEQEAVSLNADDFTVLKQCKVAKFFFAVKENNVSLITDPREIVIIQESEQNEQNILALPDYVYKAGVETLRHTSILYSREEQSLQCGYLIYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA93</accession>
    <name>A0A1D2MA93_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vesicle-associated membrane protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16776</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002302">
        <property type="protein sequence ID" value="ODM89905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA93"/>
    <dbReference type="STRING" id="48709.A0A1D2MA93"/>
    <dbReference type="OMA" id="LLVYIWP"/>
    <dbReference type="OrthoDB" id="10042941at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15870">
        <property type="entry name" value="R-SNARE_VAMP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016444">
        <property type="entry name" value="Synaptobrevin/VAMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45701">
        <property type="entry name" value="SYNAPTOBREVIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="41"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="127" mass="14296" checksum="AE9F8D0EAD886AC4" modified="2016-11-30" version="1">MSAPGQPDLEAGPAEGGPEGEGEAPMPERKRTPQQIAAEQRLKHTQRQVDDVVDIMRTNVEKVLERDSKLAELDYRSDKLQEGASMFEKQAGALKNKFWLENMKMMIIMGILGLIGVVILYYKFFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAG4</accession>
    <name>A0A1D2MAG4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_16705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01002265">
        <property type="protein sequence ID" value="ODM89977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAG4"/>
    <dbReference type="STRING" id="48709.A0A1D2MAG4"/>
    <dbReference type="OMA" id="MGANQHE"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="1"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM89977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="43367" checksum="C4C47BBEA350C950" modified="2016-11-30" version="1">MKDMVQGLRWVQENIGYFGGDPDQVTVMGESAGSASALYMLISPLAHGLYNRIIAMSGTPLQEWAIDRNPLESARRVATMLNCTEVDTGAQITSCLQDMDWMPMAQAGLAVILEEFMNFKMILPGSMPCIEGDVPGAFLPADPLELMQNGTLPNVTVLLGTVQHEGTLPLIAAYFLKLGPEGLVNDTDYLRDYLLGDVLATYGVNERMNGGSVSQAMALGFFPPDVNRSNFTEMQYYLMDLLSAVFMKAPVLRTADILSRRLPAVYLYSFEHYNRLNSLFHLAFAIIEPILGGEKPPIRPGTMHADDLIYMFDFPFILNFNDIAFSRKYCRMMTNFVISGNPTPDPGEDYPEWPTYNIQTQQYMKLALHPEVKTNFMDSWRQGMLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAR1</accession>
    <name>A0A1D2MAR1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MD-2-related lipid-recognition domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002182">
        <property type="protein sequence ID" value="ODM90075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAR1"/>
    <dbReference type="OMA" id="ERNIAIC"/>
    <dbReference type="OrthoDB" id="10509097at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="1">
        <location>
            <begin position="55"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="195" mass="22054" checksum="C27EE415DE618544" modified="2016-11-30" version="1">MTLSRGYPFYSILITISVFAPSSPANTDRQVATDNKSAFPSPFVTPFEDGSINVPISMCDSVEQKRYADLTTAYLDPPCEQTFDGFCGIRRNQNYTLIAKFLSKVQTKALSVRVTTIDAWSGFETQFWPEFSVCTSQFNITCPQNPNNLVQAYLHESLPKEVPPMRALVRVRLLGSDESNIKRVYICRQINIQVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB93</accession>
    <name>A0A1D2MB93_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002125">
        <property type="protein sequence ID" value="ODM90182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB93"/>
    <dbReference type="OrthoDB" id="8275718at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="245" mass="28282" checksum="3225C76DC29C2226" modified="2016-11-30" version="1">MTGKNRHRNKKKGGQASNTRTYFKVYATFKCSSDKCNKTWNSAHAWEREELIACEFCQTKAEVLNVVDEMIKLDNYRCPVKNCENYWQSIHDGQNLEQECDLCEVKVRPDGAQERFGRHYFYTCPNQTCAQCPEWEDFSIEPQKTQRCTKCSYRGDIIKVQKLKPVPRWVRDRQKEQLAKEGKSVGINLGGGKGKHNAEFCDMCQHIIREGKGRNCFNVRKIVCVLGKTADGVETEHIVSASREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBC4</accession>
    <name>A0A1D2MBC4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dual-specificity kinase</fullName>
            <ecNumber evidence="1">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_16420</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01002076">
        <property type="protein sequence ID" value="ODM90263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBC4"/>
    <dbReference type="STRING" id="48709.A0A1D2MBC4"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.30">
        <property type="entry name" value="DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042521">
        <property type="entry name" value="DYRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF112">
        <property type="entry name" value="DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="101"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="271"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM90263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="320" mass="36131" checksum="76565B07BB172BF6" modified="2016-11-30" version="1">MSENLSKKMDVSQKVKEPAEPSTSETEGSKTGMSLQEAFDKYGFKLSSFETREIFRYSQIYFVGEKATKINGGIDLRDTSRFDDEYGFYRFVPEDHLAYRYELVKPLGKGTTAQVFSAVDHKENHGNIDVVQMYDHFRNHACIVFELLSENPWSVIKETKKQGLPLHRVQGFACSLIKVLDALGRNKIMHGDLKLDNILVKQTGAPLSSTRSDPRHDDESDQLALGMEVFGVPPPEFLELCSRAKNFIKDGEPCFAIARLTPSQALVHPFITNKIPSPGDNEKSSFSPAAEDSQPNSARSRGTYKERRVTNKRKRSELED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDG9</accession>
    <name>A0A1D2MDG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001697">
        <property type="protein sequence ID" value="ODM91025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDG9"/>
    <dbReference type="OrthoDB" id="8296303at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="23235" checksum="CD2AA85D652BDF84" modified="2016-11-30" version="1">MAVKLCPCMPLEKGVKLLAIIDGIIGITNLLLFSFVLVGLKTHKEEFGLNDEEKQTVGPILIIEMTFSIVQIFMAVKLFDGAKLNDIRKCRTWIIVATILGLMEVCSSLKNGEELNALSFRIFLVAIVYKVYAIFVVLSFTKELAREMPVHSIVNLSATQPVALPEIYNGNQAQHQQVYYTNLECNYQNDKSPPYSSIYNKTETIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MET0</accession>
    <name>A0A1D2MET0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Esterase P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001543">
        <property type="protein sequence ID" value="ODM91453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MET0"/>
    <dbReference type="STRING" id="48709.A0A1D2MET0"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="16832" checksum="F7B703655C4F658C" modified="2016-11-30" version="1">MELVAAQVKLKEWYVYPIVLFAPVIEPEGPDSFLVESPEAILRKGNFNKVNWITGITDDDGAFFDVPIMTDKNLTDIVEKDWFDVAPVLFGYQHLPIEKRDSISSEIRESYFDRFEIDEFTWQSFRDLFTDRYWLEAFRNIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFW0</accession>
    <name>A0A1D2MFW0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein XRCC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14877</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001415">
        <property type="protein sequence ID" value="ODM91801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFW0"/>
    <dbReference type="STRING" id="48709.A0A1D2MFW0"/>
    <dbReference type="OMA" id="HEKWIFE"/>
    <dbReference type="OrthoDB" id="25840at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000012">
        <property type="term" value="P:single strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17725">
        <property type="entry name" value="BRCT_XRCC1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000008">
        <property type="entry name" value="X-ray repair cross complementing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045080">
        <property type="entry name" value="BRCT_XRCC1_rpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11370:SF5">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11370">
        <property type="entry name" value="DNA-REPAIR PROTEIN XRCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="7">
        <location>
            <begin position="67"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="7">
        <location>
            <begin position="252"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="185"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="352" mass="40071" checksum="A76E2289F85C8820" modified="2016-11-30" version="1" fragment="single">KSKKPSTQPPARAQQANHSSPKVDTNKSSKKRALSPSPPSNGASSSPSTSRGATPSKKPKKARRTKPFNKLFEGVVFAMSGYENPQRGQIRDKAVEMGARYKADWDRTCTHLLCAFINTPKFRQVKSGGIGKIVKKDWVECSYRDRCRYPWRRHCVDRSDKGVESDEEIYAEDDNDAVEEMVVDEEVPVEIDTKKDDEQANGKPKKKRILVMDSDDSDNDSKKAYEVDTDIDEDKTPDMSPSVLDSADTSDLPLPVFENLEFYICPYDETISDSKEEMEKLKELIVKRKGKVHKTPISDVEYYVCHSFDWTEEYSDALSDNPNLTFVHEKWIFECDKKDKLTDKDGYVLLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHX3</accession>
    <name>A0A1D2MHX3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tenascin-X</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001233">
        <property type="protein sequence ID" value="ODM92434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHX3"/>
    <dbReference type="STRING" id="48709.A0A1D2MHX3"/>
    <dbReference type="OMA" id="CICAGIR"/>
    <dbReference type="OrthoDB" id="5912242at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069">
        <property type="entry name" value="ECDYSONE-INDUCIBLE GENE E1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069:SF8">
        <property type="entry name" value="FI17111P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="49636" checksum="15DCEFD8C1989593" modified="2016-11-30" version="1">MIKRDVWLRVFRSGGRCEVDGQCVGESGSSGCRGGICICAGIRFFCQQSDCLLSENQSGEQCMEIQQCQKGDMGTLSICVGNDPNNKMSIVPDAISQPGNNLCRMSQLSVPWKSCKCKSEAVESSDGTKCLLKSYIDDACDDVNQCSWITGSTCQNKNVSDPATEKICRCSADYVNVEFARDVCYLKAKAIGQSCALHPIQCIDLDDSQCLRDQKICACHNLTQVVSGDKKRCLSRVAGLNTTCIESAQCSTQNSECLTTNVELKEKQCKCLRNQYVEGWEQKGKCLKIADDLRVSCEEQHQCTSGLGPLSECKDGYCLCKASYTYYDGQCYFPATLNGRCNLDGECKAGVNNYTYCNNNTNRCSCVEEAFENNNLCYGRKVVGDFCNTDTECTLNIEGPVSCDGATRRCACSWGYVPELENTICVNSALQLGTNIGIIILALIFSFSQKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIC1</accession>
    <name>A0A1D2MIC1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Persulfide dioxygenase ETHE1, mitochondrial</fullName>
            <ecNumber evidence="13">1.13.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Sulfur dioxygenase ETHE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_13938</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12981"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58905"/>
            <dbReference type="EC" id="1.13.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer. Monomer. Interacts with TST. May interact with RELA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.18" evidence="13"/>
    <dbReference type="EMBL" id="LJIJ01001157">
        <property type="protein sequence ID" value="ODM92748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIC1"/>
    <dbReference type="STRING" id="48709.A0A1D2MIC1"/>
    <dbReference type="OMA" id="DYKGDTV"/>
    <dbReference type="OrthoDB" id="449487at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070813">
        <property type="term" value="P:hydrogen sulfide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000013">
        <property type="entry name" value="Persulfide dioxygenase ETHE1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051682">
        <property type="entry name" value="Mito_Persulfide_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084:SF1">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 17" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="16">
        <location>
            <begin position="21"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00065219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00067300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00077964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM92748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="28259" checksum="B531B4C4E7C6D51B" modified="2016-11-30" version="1">MASGLSTRGLIFRQLFDRESCTYSYILGDANTKEAILIDPVFGLAQRDRTLVEELGLNLRYVMNTHVHADHVTGTGLLKETLGTSVKSVISSASGADANVKLNHGDNLSFGNFTLEVRGTPGHTNGCVCYVFHEGRMVFTGDTLLIRGCGRTDFQEGSAETLYNSVKTQIFELPEDYLVYPAHDYKGMTCSSVGEEKKFNPRLTKDIDTFKAIMDNLGLPYPKMLDKAVPANKVCGLYNLPPEMEEVLKSTNKNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIL3</accession>
    <name>A0A1D2MIL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13849</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001137">
        <property type="protein sequence ID" value="ODM92836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIL3"/>
    <dbReference type="STRING" id="48709.A0A1D2MIL3"/>
    <dbReference type="OMA" id="ASWIHFF"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000036">
        <property type="entry name" value="CYtochrome P450 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM92836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="505" mass="58106" checksum="EFB264F532F360CB" modified="2016-11-30" version="1">MAFPLVGVIIATSLLVWFLLQRRKKNESKLSHLKEIPGPKGLPFLGNVLQLGTFPNDQFTKWSKEYGAIYKVNLGSQMVVIISDPKLCKEIFTNDPVYTGRPYFEGFDIYLEHPGLGMFASEGDLWETHRRFLLRQLRDFGFGKSSMESLIMDEVNEVLERFQKAEGKPIGQMRETLRLAIVNSLWTILSSQRFKHDDPKLSQLTENIIKSFDNIFEGGSLLIFLPWLRHIIPGYSGYTTMRKEMEGFKHFLEGSVNQHKRDLKEENLKDFIDVYLAEVRKTTDEKSPFYGTVAERQLVATMLDLFLAGSDSSATTLSWTIVYLCKFPEVQKKLQKEIEAVTGNARQVSVTDRPNMPYAVALVDEILRHSSIVPDGAQHRAMAEREFHGYRIPKDAWIQPNLFFIHRDNKIWGDGDSFRPERFLTADGKKYVKSDSLQPFQVGRRVCVGETLARDNIFLYLTNIFQKFDVKFDPKGKEPSLETIPGFFRAPEPYTVIMKERLSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ83</accession>
    <name>A0A1D2MJ83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001092">
        <property type="protein sequence ID" value="ODM93039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ83"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ83"/>
    <dbReference type="OMA" id="NLMRESR"/>
    <dbReference type="OrthoDB" id="10262032at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007914">
        <property type="entry name" value="UPF0193"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28348">
        <property type="entry name" value="UPF0193 PROTEIN EVG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28348:SF1">
        <property type="entry name" value="UPF0193 PROTEIN EVG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05250">
        <property type="entry name" value="UPF0193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="279" mass="32616" checksum="2198234AA2741AE0" modified="2016-11-30" version="1">MSIPTYGMRYFMPLTKGAPKDGPTTSVFSVPKVQYSPQTEAVVKNLMRESRLTFTQKHVFDTILRSGKSLPEHPEQMMASRWRQAYMQQRHKNKARRLGMELLNLEDSYRPPTLFHSYIRRGQSAPARRTLESIKASGDLERLPPPKTYIPLNKEAEKDRLAHKMAFGKDPPVEPVRTASKDVKQKPKKTMNDLKQERFEELIDEVQDRMQFLLSMDQLKKGKQYRACIISQINEKLQEMKQISPQKEKDVRDCLELELLDERLGSKFAEEHRTSKFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJH9</accession>
    <name>A0A1D2MJH9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001059">
        <property type="protein sequence ID" value="ODM93158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJH9"/>
    <dbReference type="OrthoDB" id="8293317at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="1">
        <location>
            <begin position="60"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="136" mass="15611" checksum="85E3412D4E61531F" modified="2016-11-30" version="1">MQHSNQLLVGTYDGVKRKRDILGKLQPGFQRIQAMNLHQQGQQPQPRADVPQNADTIFQALLDDFERLQMDALKHTSSHATTQYRSLQERCVKLEMALDNLNVKGREDLRNKRKTVLINVNLVSKNLSENTHSHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJR9</accession>
    <name>A0A1D2MJR9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_13423</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001036">
        <property type="protein sequence ID" value="ODM93259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJR9"/>
    <dbReference type="STRING" id="48709.A0A1D2MJR9"/>
    <dbReference type="OMA" id="HGQEKDF"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000176">
        <property type="entry name" value="zinc finger protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050826">
        <property type="entry name" value="Krueppel_C2H2_ZnFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24377">
        <property type="entry name" value="IP01015P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="295"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM93259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="327" mass="38226" checksum="73CA0529A0AD0547" modified="2016-11-30" version="1" fragment="single">MEKQQMKKNPPFAKKTGKKSLSNSRLNNHKCEFCNRTFKNLQSHLKTHIGVKSHSCLFCDRAFLRSADLNLHLLIHTRERPYECQICNRDFGQRYGRDQHIRDIHSLERAYKCGWKFERSSPSAHRGKKFVCIFCEKAFSHSHTLVNHLRAHVQEKPFECSFVIIIWSKSCNDPTHQVAHSRKSLFLHAIFEEYLPTRNLLRHIRELTISCKVCGKEFAVLADANTHETTVHGLTKRFQCSLCEKKFSLRYLLNLHIRRVHTNEKPFKCNECGMCFADSSKLKSHLLQHRNETQFRCVTCNCFFASSQGLKTHQTKIHRNQITPSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK93</accession>
    <name>A0A1D2MK93_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000999">
        <property type="protein sequence ID" value="ODM93403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK93"/>
    <dbReference type="OMA" id="AFCEVNS"/>
    <dbReference type="OrthoDB" id="10687946at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="851"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1064"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1076" mass="119010" checksum="7C2107F51FC78E28" modified="2016-11-30" version="1">MKSRHRSTFSLSSPLVVVAVGVLCIAYIQLSDSAPTSESSSSSSTTSTTSGTKPTRITTLRSGKQRVENTAGRMKASDIKACISKAFCEVNSASRKPNYAVNQEFFDIMDQIRSLSNEDIDSGSVSVEYDEDEEEEDDDVESSEESSSERGYPGPPPPGYHRMGKKIKDGVNGTSSVDSARNSTVSAVKKSKGKKDGKKKMKVKTVKKYVNGTFISVPKRRHSRVETESEKAEKAAYLTRKQREMGQVNDLAALIRISADIGLTLRSPHKCRTLFNKCTMSHEQIVDLFNQTLMAVTTPASDNINANVVSTQTTRIKVHTTQASPVTEEQQGTEVSEITTASQAPSTTSASTTSSPTTTTIDNRNSKSRHDFSDEDVEYMTDTEIQPVATYALFVNDPVDDNMRTAETDVNVQDTFKKYANTFPAEASYPVDLPTLRKKSNKVSKSKKKKSSFNRKLMAHKHKASSEEEDEDDDEEEEDEPTSSSTESHKSGFRIESPYPGYRVEANKEEELEPESAEPTSMVKDSSEGILPPLVQKTEVKNSSKKPTTDDDEEVDEDEENDEESEESVEENIEQRAVKPLNKKYKKKAVEPASPAPVEEEESSEEDDVETADDIEPADDDQQSAPPPWTPVYQRYMNQKQKQGYKKKQKGPYKGGEHPYDDSPHVASSANKPWAGGASHELGNVAASSHESMYGDSPYHGHPPPYEVGAEKPGFFQSIMSWFTGGSKTGEQSPDGHYPPQPMAQHQHQHPYSQESPTGAPWPSQPDPGHVGHYQYEQHPHHQHAPSQYRHRDSSEDSDEDEEAEVEEFLPKKKSKKNKRRRYRGRSDSIINAELKKPASSSRKTGPPAPVVVVPKENKPNGSSGSNSGVGVYEPNSHYDTLIKADGGITAGSNLKGKNSGKENKRTKKAAIKPKQKKKNQKQSQRAHGSNESHDDDDEAYSSEELFNKQVQKLKSEKVGTTNSASSNNGKQNNNEASATTETSFPKYFESMFGNEKKKDPFKPSGKDDGSLLYGFDLLSSTLSATPMDLPALPKKKGTYTINKTKKKKKGTSPPVQFNQKEVINSSEENEEKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKR1</accession>
    <name>A0A1D2MKR1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CARD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000990">
        <property type="protein sequence ID" value="ODM93434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKR1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001315">
        <property type="entry name" value="CARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50209">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CARD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="19472" checksum="FD0E29BDC25EE0B2" modified="2016-11-30" version="1" fragment="single">MDRNAKKAILKNRVKLLNLDYFDLTAPLLASEIFTSKKHKDIKTSALDSKARVDLLLEWLEESAPKEAFPIFLQGVRNCKELILAKKIKREASGTVLASGSAGTSATSIPLDKLLAEIVPGLPSSIGKPPTDKPKKPKAAKLKLPKIIPPTTTGVPPPPPINGLPSTSLPPPPVPKAKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKX1</accession>
    <name>A0A1D2MKX1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000945">
        <property type="protein sequence ID" value="ODM93613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKX1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904204" evidence="2">
        <location>
            <begin position="26"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="516" mass="56232" checksum="83350904F2F3992E" modified="2016-11-30" version="1">MEIFGWSLITVLIVWIVAPWNEVAGGVPFQQDPTHPDKSSNKHEQPLYVDTEDYPTGGVSPVRKRQPLRVVKSQKVAANNFNSPIIPWEIRSISPKSNRTRKNSTNSQTKALASSASATVVLNGGLTNQSSLSPTPSNTESSDFDLLGGLMAEAVNEEDDAYKSRLRRMYPVFTQHGFMFTEDWFFHTTVMPPKSSYGPCVTGLGFEDNKYCAPGEVCADKTTMQEAVCPGKVCPACGAGPKPPKPSAPCPPGCKPGANCPDPSPDGVCIDSTFGTDQYDDVSTSEKDPSPMVYFGGQLKQNDSCVAYGDAIDMFNRGHEEFNDKMRKLRLTPESSGTFGSGICNWAVSRLQCIANEPRIPPTPAPPPPAAGPSPSDDDENLDRPKGSCKCMLALGERAVAVKNVNGTAICYIPANRGYHSKCSHGIYLPYGGIDGVRKDGKPYVKLQMEPASKFCVPNGECKPGYKYTGLRCMCKKNYVWEPHTSTCSKAWRLKPQSRSGSIIIFYALLCFFRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML49</accession>
    <name>A0A1D2ML49_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Muscle M-line assembly protein unc-89</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12903</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000916">
        <property type="protein sequence ID" value="ODM93779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML49"/>
    <dbReference type="STRING" id="48709.A0A1D2ML49"/>
    <dbReference type="OMA" id="DARPKQF"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000097">
        <property type="entry name" value="Bent, isoform F"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000107">
        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="6"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="213"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="319"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="426"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="528"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="619"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="716"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="827"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="810"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="912"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="816"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="919"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM93779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1029" mass="115808" checksum="37F4BEB8E6C46173" modified="2016-11-30" version="1">MGESVPAFTQKPQLRQEDDGNRLIFECQLVGAPQPDITWFRGETELKADKRTVFKNTKIATNKYLVVLELDNVIESDAGLYRVKAKNKNGEVFASINLNFSPVDEPKEKEYADVIFPSVYFSKRGNNNASYFLPKRLHHLAHVQCYCAAPIPWKVCCNAPTVLLNQFPSAKKNLRADSLRNERKKCYVSPFHIMWPILLLFGNGSEQIDGVAPSFAQKPVIRQEDEGRRLVFECKIKADPKPSVTWFHEGKQVASSSRHRLIVEKDGAVYVAALEIKNVAVEDAGKYKVTAKNELGESNATISLNFDRDSGESKKPVKPSFSERPVIRQDESGAITMEVRLASDPEPNVTWIHKGVKVSSTRIKTTVTRESSQDVYYMSRLTISNVESSDEGEYKAVAKNEHGEATAFVNLNFEGGGIKIPEGKAPRFPKKPTIKQKGEFLVMECILEAQPLPEITWWQGVKQIVQSERIKMSRKDAGKDSYLLSLEISNPVIGDAGSWRCNAVNTCGESNANITLNFQASHHPNATGTLITMLCRCKANPAPEVTWFRGTTQVKESSRIAMRIKDVDADIFDLILEIKEPGGQDGGTYRCHVQNQHGESNANLNLNIEAEPEPAGQAPTFVEKPKIVSEQNGRLIIMECRVKADPRPSHTWTCDSVEVTKSSKFSMSIKEEKEVYIIRLEIKEPAPEDSGLYKCNIKNEFGEINANLTLNIEIAPVIMQQPRIVRVQKTKVVLIETTVNCQAPPDVQWFKEQTVIKQDNRRTINIQQVQKGEYKIQLEIAQASREDKGSYKVMARNEKGEVTSQTVEITDVPDEDEKKPAPKGDAPKFAQGLKSTTVEEGKSAEMYVELTQVDKKATVTWYKNTTIIKETKETKLTFDGKTARINISSCTKESSASYRVVIKNEFGSNESEATLTVQETKKVEEKKEEKKKEPEKKKAEPEKPKPEEKKEPEKPKPEEKKAEPKPEEKKEPEKPKPEEKKKAEPEAKKVEEKPKDAKKPEEKKAPEPKKAEEKPTEEKKGQSLKKAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLN4</accession>
    <name>A0A1D2MLN4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000877">
        <property type="protein sequence ID" value="ODM93979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLN4"/>
    <dbReference type="OMA" id="GTERITH"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="26456" checksum="AE8F5278E531DA23" modified="2016-11-30" version="1" fragment="single">MASEQESKYARFDLRKTGWEYFRTYPGILRSANVVLGFLSLILVLLGFPNDYSSEDLEDKYERRKVPWYRITGDSSASNSPDYYGTGYVAEHPNIVQLICIVITLVFSFLFLLGLATSALCQTQGKSRGWNRFLNLTAGFLQAVGLLSGTFGLLLFRSYCCHVEFLSSDRHKSEMEGYREDCSCYFTPMWNDNSVAEREYLTLYYRDVPDDIAYYYVLPHHFYPHAICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLZ3</accession>
    <name>A0A1D2MLZ3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BBSome complex member BBS5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_12625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BBS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000867">
        <property type="protein sequence ID" value="ODM94049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLZ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MLZ3"/>
    <dbReference type="OMA" id="PNFGIQY"/>
    <dbReference type="OrthoDB" id="10261999at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006606">
        <property type="entry name" value="BBL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014003">
        <property type="entry name" value="BBS5_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21351:SF0">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21351">
        <property type="entry name" value="BARDET-BIEDL SYNDROME PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07289">
        <property type="entry name" value="BBL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00683">
        <property type="entry name" value="DM16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BBSome complex member BBS5 PH" evidence="9">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="BBSome complex member BBS5 PH" evidence="9">
        <location>
            <begin position="138"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM94049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="37881" checksum="1E86C62946BF2E80" modified="2016-11-30" version="1">MTRYLKPCAGEKIFELIEPVEDTKGNNGEPGKLIVTNLRIIWQSQKYPKINLSIGYNPITSISIKSATSKLRGMTESLHILAKTKSSRYEFIFTNLVVDHNRLFPVVLGFTVKTLQRDKNDESAMIVSNKKLQMLPQEQICEQISGVWNLSSDQGNLGSFFITNVRVVWFAAQMSYSTLRFHFFRSLRDSKFGKALVIETTEFGGNYILGFRIDPKEKLQSVYKSLLSIHDTYMAYPEFGVEFNPDSIDAEIEQERKDRLHRAITEEVEEIDENPELASDAFAAYFADGYTGESQNAHRRQIVYSEELGLAIEKPKDGFTLQQLWEVIPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMH5</accession>
    <name>A0A1D2MMH5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000851">
        <property type="protein sequence ID" value="ODM94158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMH5"/>
    <dbReference type="OMA" id="INDFFAC"/>
    <dbReference type="OrthoDB" id="10507371at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904262" evidence="1">
        <location>
            <begin position="23"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="132" mass="14165" checksum="EEDD803C4F0167E5" modified="2016-11-30" version="1">MKTIIFAVGIIAVLCCATSVSSENLVSTLRIVAKLCYIPGNSKNQTLINDFFACYDTAPGKDLFVKCQTKMFGGPMDNVPVVAGSCTQPQKIPTYGICLTNEFRAAGLDMNAAVKTLNACQMKALNIRSCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN17</accession>
    <name>A0A1D2MN17_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrin alpha-L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000802">
        <property type="protein sequence ID" value="ODM94470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN17"/>
    <dbReference type="STRING" id="48709.A0A1D2MN17"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033627">
        <property type="term" value="P:cell adhesion mediated by integrin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.930">
        <property type="entry name" value="Bicelle-embedded integrin alpha(iib) transmembrane segment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018184">
        <property type="entry name" value="Integrin_alpha_C_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220">
        <property type="entry name" value="INTEGRIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220:SF83">
        <property type="entry name" value="INTEGRIN ALPHA-PS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00242">
        <property type="entry name" value="INTEGRIN_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0401">Integrin</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="322" mass="35785" checksum="56893050158C81F5" modified="2016-11-30" version="1">MTILDFSTGVLGASVGSLATEFKVPIYDGANNEKKPLFLVLQPEMDPKDWAHCTTKLGFHQVKLASSQNYAPTDDSQQFQHASTRELLNPPLAAEETASNLKQNENNENGSIAIAIDRMLPIPPTKANLLKTSDDALKLSCTSEETSCMEIICTASNIKAKSHYHIQFILYPIKEAIDDIIKSSGKSRILVEGKGYAHIFSAKKHHQDDDAAQTILSIDDSKVELWIYIASGTGGLLLLLLIIVALYKCGFFKREKRQQLNHMKAEHHRKSMMVRASMMMIQSPSSTGTEDFGSQDMLAEAEHQNEDLEPEQTTTTETKDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN48</accession>
    <name>A0A1D2MN48_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000800">
        <property type="protein sequence ID" value="ODM94500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN48"/>
    <dbReference type="OMA" id="STYHESH"/>
    <dbReference type="OrthoDB" id="8287884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="31935" checksum="0980E94DA2E90B66" modified="2016-11-30" version="1">MSGIQDLLTLDSGSHCNSEGSGLGCGISRIAGSLSGSSLASSLLLLSSSHFQPVESFISFVSLQSSYAWYMHLSDFETVFLSLVMLQVFILRYLEILPINVNNLFLGESSGRRKKRSFWKTNQFNCESDLLTQSLFKVLKKLDHGNCVALTICELESMSTYHESHFSPNNQHSLELPTETKALLKALKLSAKYRSKSFSRPISFHTNEDDTEDGNEVVNKPENSDPSTSSYCAAIDGLKKYEEAVLIGSSAAATHAYANSTLCEDKYSACPLTKEDIEHYVGILVDANVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNG8</accession>
    <name>A0A1D2MNG8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">[histone H3]-trimethyl-L-lysine(4) demethylase</fullName>
            <ecNumber evidence="4">1.14.11.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_12287</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 2-oxoglutarate + 3 O2 = L-lysyl(4)-[histone H3] + 3 formaldehyde + 3 succinate + 3 CO2</text>
            <dbReference type="Rhea" id="RHEA:60208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.67" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000811">
        <property type="protein sequence ID" value="ODM94394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNG8"/>
    <dbReference type="STRING" id="48709.A0A1D2MNG8"/>
    <dbReference type="OrthoDB" id="1678912at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034647">
        <property type="term" value="F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048615">
        <property type="entry name" value="KDM5_C-hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004198">
        <property type="entry name" value="Znf_C5HC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF33">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21323">
        <property type="entry name" value="KDM5_C-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02928">
        <property type="entry name" value="zf-C5HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="19" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="17">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="ARID" evidence="16">
        <location>
            <begin position="96"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="15">
        <location>
            <begin position="229"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="18">
        <location>
            <begin position="366"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM94394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1269" mass="146019" checksum="F5FDC23781D60251" modified="2016-11-30" version="1">MSDSLAVNAVNGKMMGKMSGDAFQFVRPAEAPIFYPTMEEFDDPLQYIRKIYPKAVQFGICKIKPPPDWTPPFSVNMDEFTFTPRVQKINELEATTRIRMNFMVHITKFWEIQGTPLDIPVFDGKQVDLYKLHHVFNSNEFKNGKFICDDRKWQLIADTMGLKSEDGQTWNDLGIKLKLCYERILHPYDIWKATNESKNAIKSRKPRKGRADTRTAMRYRSKVKPKLISNDCLICNICDQNELLKCSDCHLKYHPSCLQLSLDITSKETWRCADCVSDKLKEFSEEYGFEQAVKQYTLQDFQKMADDFKADYFNGTPQDISSEDLEKEFWRIVSTVGENVVVEYGADVLGTGFPTSKTNNAGEFAGYVKSGWNLNNLPVRLGSAFAHIKSDVSGMKSPWVYVGMCFSTFCWHNEDHWSYSISYLHRGATKTWYGVPGGKAAEFEQAMRNAAPELFDKAPDLLHRLVTLVNPNVLMKAKIPIHRMDQNPGEFIITFPRSYHAGFNQGFNFAEAVNFAPADWVPMGRQCVQNYSRINRVCVFSHDELVCEMAKEPETMDYHLALATYHDLLDVLIAEKKARCEAISLGIKSCERFEFETIADDQRQCDVCKTTLFLSGITCSHSKLSGSPEKFVCLKHFDQYMCKDCKIDPTKYILRYRYTLDELLDILKTLKDKLELYALKAKVISVKSFATKSSTKELRLLIRAVEQSLCPDAPIKQEQLVVEDSSARSSVSLRARKNNSQFQDVRFKFNVSEWKVIRKLDDPDSIHQVPFRDYQCTKNDIEELKTIYDKARCWESSALAVAYREVKVTDVRVMSLLDEAEAMPSIHFPCKTKLQNLLKEAAAWLEKVESAKIPSTDDWYLHEIPDLIWEGEKLPMHVNLVEEFKSFKAMTERWLTKCSNEFLLPGYEFKLIEVLIPRTLFQYTHLNEWSNVQCKLIRHSLPSHFQVLESTRLSLKEIKDFDKLMTAIEKTMDDSCLLVKRRRSENQCKLSTRSVFTSFCYCKEKDGDTFDSSFMIQCELCFELFHPRCVSAALSSDVSVGRRTINGSVVHPCFHEVVPKSSKYIGPCCIRSCRPAPERIEKLIEEVVEHKVIPIELHYIVTLTSRLSKAFNEWIEFKTSTEGKIFSEIKSPAPTFQDLLSTSLERVNIVRGLATLEDLAIKIAVLPLRSYGEKYNFSEFWSLYFSFKHLVISRDKCPVQKSLIIPLPIQSNTNSSAVIDAHIAENYQRSSTTRKRKQSSCSRVDPVKNPADDEQCFMFFKPAKVMRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP30</accession>
    <name>A0A1D2MP30_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_11906</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000752">
        <property type="protein sequence ID" value="ODM94773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MP30"/>
    <dbReference type="OMA" id="YDYEREC"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056850">
        <property type="entry name" value="ARM_UBP34_24_USP9X_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021905">
        <property type="entry name" value="DUF3517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055176">
        <property type="entry name" value="UBP24/USP9X/USP9Y_UBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF925">
        <property type="entry name" value="UBIQUITINYL HYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25010">
        <property type="entry name" value="ARM_UBP24_USP9X-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12030">
        <property type="entry name" value="DUF3517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22900">
        <property type="entry name" value="UCH_UBL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="1638"/>
            <end position="2022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1061"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1669"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2545"/>
            <end position="2612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2715"/>
            <end position="2763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1061"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1672"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="2548"/>
            <end position="2562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2563"/>
            <end position="2575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2600"/>
            <end position="2612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2721"/>
            <end position="2730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2750"/>
            <end position="2763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2763" mass="314746" checksum="3C0489C0A136FCBA" modified="2016-11-30" version="1">MTNLHETQKPLDRQTAVNPASHNQLQSILEVSNSGGGSGEDSPMSTSTTTGEDTTPSLQFTGEDSEVKSDVDSTTTMVSVNESEESLYFLPREESQQNSNERLEQLYKSVQELIPPDKVVQEEQVQEQQDNDGVQQQTSSMAVSPSRVPVISFPLADMARLDEMISNPRWVVPVLPGGHLETLLAASIDLATRGFDEKCEPCQRFYREGLTISFTKILTDDAVSSWKPEIHKAILKNCERLVELIVVKLRVDWFPLFDLMSTLFNPTNKFHMFNANRQPETYSPDVPVGDDELFARPIEMRQCKGWLVDLINRFGSQGGFDLILKRFTNPAGLNVSIIFSLIRPFGRCAEFLTRHSVEKYFTYILTAVPQILENLSDDELKKETAKSDIISSVIKCLKALQSRSSESEEQMKSLELFRLRMILRMLQVSSFNGKMNALNEINQVIQNVTSHYTSHHYRLDEVEYLTSKNIADWFAENQVLQIVLRDSLHQPQYVEKMEKILRFIIKERSLSLKDLDDIWAAQVGKHDTIVKNVHDLLAKLAWDFSPDQLDHLFECFQTSWTTANKRQREKLLELIRRLAEDDKDGVMAYKVLTLFWNLAQSTEVPTEIMDQALTAHVKVLDYSCSQVFVIKHQRDNQKFQWLNKSMDKLIEDDVAWVIPAMKHMNEIFCLYPEGSATNKNPATTYRAQIINKLQNDRQLVVKVCESLNSYLEKVRAYVKDKGVLDPHQVKLDGRYSHLDQIKERLTFLLSFLKAGELCLCEEQANSIWHCLAENPAFSSDREMCFEWFSKLMNEPDPDLDPNIIQPFFERKILNFDPTLLTECGLECFERFFKFVNIRQQKLVVNKRDEISMDDLELTGTDYIWKIILCGSEDMASKAICFLRQICTALGPKLLPNQVEVHDDFLSSCSDRLKASYDTILVLERDKDSTNRVRQEVTRACRVLRVLFEYVVECDAEYGEERAFIPLYRASRGKNFVVYIRFPGPSGRGFDDMEVLTHTNETPAGLRRQIIRQVKEQMQINSGFKLDVFYNGEIIDLSDDRRTVHQFGLRDKMVMQAKLVHSNVPNSPDSSEESSGGSPNHFTSGTDGPNADAEESLPSVMMSISEKRMTFLCKLCELGANIGEDRLRDAARLNLSVCYTVKSLKEAFLTATSPLNDKKPYNLMFNTDPATVLYRLEVLYALLFPAVSVHGSQTLELLQKFFIAGGASMVVEMLTKNNFMPLADTATKRSAYLAVLKLTKAILTITSHLLFRYESEGNTPARSERLRIVSEAVKAIPSPGSEVTLRQTAERVSHGLFTYWKSSTPEPLKEGLKLLLVSAVEGSLPDLETVRLLIKLASSAATGSLAYLSSEQHQANREPTDDDIAVCEEALETLTLSFVMNHGALEQVINEQMWRNFVRQVLFHSHSISIRAVAAQQFYSIATKCTRNDNALNFFTIFLFEIIQNSVREMPQNSMHVFQLLCNLLRYSHTYNVPMQKHELLLNTQIDWLRQAKEYVKRNGEGCLQEDLLEGHICVARELTNFLIPDKKYELGCDPSGNTNSLIREILEEFVFPWSKAYSHMRKTGEISFESPIQVCSNPNTQIAILDLVVSLCTSSNPNLKLTVEILTQLFGYSLDGEGTLNEWEYFPPVGSRPMGGFVGLKNAGATCYMNSVLQQLFMVDPIKRGVLGVTDGDGDSTNDDGAEDVTARDSTDSVALSQTSIATADSNTDDRKVYNVCILKQIQSIFGHLALSKFQYHIPVGLWKHFRLQGEPVNLREQQDAVEFFMSLVESVDDGLKAVGEEQVMSKNLGGLFSDQKICKECPHRYSKEEPFSVISVDIRNHSNLLDSLEQYVKGELLEGADAYHCERCNKKVVTVKRLCVKKLPPVLAIQLKRFEYDYERVCPIKFNDYFEFPRELDMEPYTVSGLAKIEGEMIDQDDAALLGQNVCTKFRLTGIVVHSGQASGGHYYSYISFRCHDGMWRWYKFDDGDVSECRMDDDEELKNQCFGGDYSGEVFDHMMKRMSFRRQKRWWNAYILFYTRCDVFDTAISAKLSSLQIDSERRLKMPAAIERSVLKENVEFMHVRSHFSPEYFQFVKKLVAANHHLMPQNITIEAPNEEVEQLALLSVQLATQFLFSIGFRTKKNLRGIANDWYEFMMPYMRVSKTVRSWFATHALFVDSCRFGEYLLECPSSEVRQTFSKLLIYLCHCSKNDGTYQPSVPMATLSRRIEKEGQLWEYILETILQLLRRELSEYGRHLVQYFGFFVAYANLGDKEKANLLKLEVPETFMLLALDDGPAPPIKYQCADLGKLHQTVSLLVRSCDVSELCKSALTTDAIGPNPFRVETQSGKPIMSLPRNLEELLYRYGDSGCNPYIKKLIDEAYTSEDTITLLQFLCWENLSFSEIAVMEVLSRIGYSYTTDLKAFLDLLISILRIDDSWQSERIASALKGLPDEKDGLIDIIHRNKTSHPKRAYLFIKCVTNLMEPNSIAHNVLVSVPDLMTKWNAAVQWLQHELERRAPACSSTYGYSTTSWSPPSNESSNGSFFLERSLSAKHTLERALELRIDPEQVENEDDQISSEGEDGIRTTAEFESKSPSKRSFVSSDKRRRMKAKSSLGKARTNQTPERSSVSQVKDHIVVFSTAEETKSEPAEKTDEFLSKNCYIDKEFNPSNGVPWDVSEAVRRAAQVMEPHDAEETESDNDFRTVQNKEAFYKQYGENFVKVTEKFGKLSVLNASESPAEETKEVDVKDQTVTTANTQETSSKEEEEDDTHRSVPEKSEING</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPC3</accession>
    <name>A0A1D2MPC3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein phosphatase 1D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000732">
        <property type="protein sequence ID" value="ODM94940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPC3"/>
    <dbReference type="STRING" id="48709.A0A1D2MPC3"/>
    <dbReference type="OrthoDB" id="10025511at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="358" mass="40396" checksum="1E576D67889D05CA" modified="2016-11-30" version="1">MDSDQDPVEQPVTLNGAGEDFGQRIYYTSCQDKGDLELMEDRHQIAFFDVEESPFDDQLGFSTAFFAIFDGHEGSEAATYVESRLLELITSNKHFNSDDDTQILKAIKKGYTKLQKDMKFHWMNNWPKSKCGNPSVSGTTASVVLIKNGKLYVVHVGDSAIVLGYQDPESPVWKAETLTKDHLADSPVELKRIEHCGGKVKMDKNNGIPKVIWKQPQLAPDRGDGGHGYLTRTSTVEPTPFLHLARCLGAFWSYNPEREEYIISSEPDTMVVTLDSSKHRCLVLGSKGLWNVLPAEKVVHLIYSLEWNNDRRRKNARKEGRKCYNLIHHSGRLVSRVKHKCGVSKQEADNISVIVVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPM3</accession>
    <name>A0A1D2MPM3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrocephalus-inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000730">
        <property type="protein sequence ID" value="ODM94956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPM3"/>
    <dbReference type="OrthoDB" id="442692at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="88" mass="10183" checksum="DF8237601D45E30F" modified="2016-11-30" version="1">MYPNQVRETKNQLKCWITDMDGNDVETVASINIRGTVIVPELRAVKSHVYLKECYLQFPYEGEFVVKNPTELPAMYCVILKVRHGTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ58</accession>
    <name>A0A1D2MQ58_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000704">
        <property type="protein sequence ID" value="ODM95156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ58"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="127" mass="14131" checksum="7948B770DCF17863" modified="2016-11-30" version="1">MESVVIGVAAVAIIISILQIILALRLFFAAKNRDYRNCRIWIIVTVIVVVINIASLILNSTSGEFDSLSFGITIFLVCYKLFELLVVISFLRTLRGADRNWEWGCMYATSTVPQPGTGPHYPAQHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQU9</accession>
    <name>A0A1D2MQU9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11304</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000681">
        <property type="protein sequence ID" value="ODM95376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQU9"/>
    <dbReference type="STRING" id="48709.A0A1D2MQU9"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="OrthoDB" id="1677536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="16221" checksum="9B211E83C1C10A9B" modified="2016-11-30" version="1">MGPRKTRAPKEEVQISLGPQVRDGELVFGVAHIYASFNDTFVHVTDLSGRETIARITGGMKVKADRDEASPYAAMLAAQDVAEKCKSLGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR67</accession>
    <name>A0A1D2MR67_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heterochromatin protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11463</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000696">
        <property type="protein sequence ID" value="ODM95215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR67"/>
    <dbReference type="STRING" id="48709.A0A1D2MR67"/>
    <dbReference type="OMA" id="REFQIKW"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017984">
        <property type="entry name" value="Chromo_dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00504">
        <property type="entry name" value="CHROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="115"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="215" mass="24348" checksum="BDE5D3A6E45B988B" modified="2016-11-30" version="1">MARAAPKSKKRPAPKQKKVEKKEEEEVDIKDEEHQEDLDNGNEVNNVSDAADEDEPPVKKGRGRPAGKAKGSKKAASTKKPAARGRPAASSSGRKSASKKEEEEKDDSSEDDAEYEVEKILSMRKVKGGREFQIKWKGYSKAKSTWEPEENLNCNDLIKEFEETEKEKPVRSLRAVPKETQRYVDTADLKYEGSKRHSNRLGKSPRKTYREAEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRR4</accession>
    <name>A0A1D2MRR4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Palmitoyltransferase ZDHHC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000677">
        <property type="protein sequence ID" value="ODM95415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRR4"/>
    <dbReference type="STRING" id="48709.A0A1D2MRR4"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="104" mass="11881" checksum="EDE9316013E3913E" modified="2016-11-30" version="1">MTPPYGDDRREGPGGACRTCINITKWMPVLFISAVISWSYYAFVYQLCILAMRQLWAQILSMANLSRSIDVMERLENARSETELTEILEEFKNSTIASADESTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS35</accession>
    <name>A0A1D2MS35_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoglucanase</fullName>
            <ecNumber evidence="9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10785</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the glycosyl hydrolase 9 (cellulase E) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000610">
        <property type="protein sequence ID" value="ODM95900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS35"/>
    <dbReference type="STRING" id="48709.A0A1D2MS35"/>
    <dbReference type="OMA" id="PSWRGDS"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033126">
        <property type="entry name" value="Glyco_hydro_9_Asp/Glu_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22298">
        <property type="entry name" value="ENDO-1,4-BETA-GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00698">
        <property type="entry name" value="GH9_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811344" description="Endoglucanase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 9" evidence="10">
        <location>
            <begin position="27"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM95900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="49990" checksum="83F872AECF60F348" modified="2016-11-30" version="1">MAIFSFKSAVALGILSCAAVTLAQYNYGEVIEKSILFYEAQRLGRLPSSNRIPWRGDSFVNDRGENNQDLTGGYFDAGDHVKFGFPFASAMTMLAWGMADFKQGYVKAGQWEQAKDALRWGLDYMIKTHPEPNVLYVQVGDGNRDHAYWGRPEDWPADDVRPVLRATTDRPASEVAAEQAAAMAAALKFTAMMGIPLSHQLFSNMLGIFTLLPLSTGPSTATHSQNSFSGFGDELLWSAAWLYRVTNEDRFKQDYETFFTEFNLNRQPVEASWDDKTAQAQVLLAKVDRSAKYVDAARTFCDWVVDQAPKTPKGLVFISQWGSLRHASNVAFICLQAAEAGINAEKYRAFAKTQLDYALGSTGRSFVCGFGNNPPQRPHHRSSSCPNRPAPCDWQAYNSPDPNPQVLTGALVGGPDQQDQYTDDRGNYVSNEIAIDYNAGFQGVAAAVNQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSJ8</accession>
    <name>A0A1D2MSJ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidyl-tRNA hydrolase ICT1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000612">
        <property type="protein sequence ID" value="ODM95871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSJ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MSJ8"/>
    <dbReference type="OMA" id="WYNSFDA"/>
    <dbReference type="OrthoDB" id="270639at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016150">
        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070126">
        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110916">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="19379" checksum="3AD2EEC16756B473" modified="2016-11-30" version="1">MSLRLFSRILQLQPAVRNCSYKSAISLDKLYPQSSLSITKVPPPPPNEPTKFSGYIPIVNTKANVKFNVHEASWLPDAIRDNLKLKFKNHISKDGFITLQSDRTRYQHLNTADALQKLREMLRSCEPVEIKEPTPETAEKLRRRREKAARERLLEKRARASVKSSRGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MST9</accession>
    <name>A0A1D2MST9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vitellogenin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000571">
        <property type="protein sequence ID" value="ODM96147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MST9"/>
    <dbReference type="STRING" id="48709.A0A1D2MST9"/>
    <dbReference type="OMA" id="TINGACT"/>
    <dbReference type="OrthoDB" id="5956066at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.230.10">
        <property type="entry name" value="Lipovitellin, beta-sheet shell regions, chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015819">
        <property type="entry name" value="Lipid_transp_b-sht_shell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015816">
        <property type="entry name" value="Vitellinogen_b-sht_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050733">
        <property type="entry name" value="Vitellogenin/Apolipophorin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001747">
        <property type="entry name" value="Vitellogenin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345:SF15">
        <property type="entry name" value="VITELLOGENIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345">
        <property type="entry name" value="VITELLOGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01347">
        <property type="entry name" value="Vitellogenin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56968">
        <property type="entry name" value="Lipovitellin-phosvitin complex, beta-sheet shell regions"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51211">
        <property type="entry name" value="VITELLOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0758">Storage protein</keyword>
    <feature type="domain" description="Vitellogenin" evidence="4">
        <location>
            <begin position="11"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="248" mass="28264" checksum="78BC65F89B949DAB" modified="2016-11-30" version="1" fragment="single">LHVSFGSRQLFTVGDEYKYNYEVLITTGTEEPVSHAASYRLKGVLRVQGTAQNRVTVKLEDVGIGLFNGQWSYFPVPSVNYLPLEELNSLSEPFQIVSENGKFKTLLMNDQEPEWASNMKKGLATYLQMNLERVSPQKLMFFKDEESTTMGICPTMYEVMPATATGMGLARVSKFRNHADCPDVPSRIRHESRTYYRCNDDRTRDIMNSTSYSIYDLSVQDTSITVQKVTVLSSILFWANDSKRTFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT48</accession>
    <name>A0A1D2MT48_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein anon-73B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10817</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0239 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000612">
        <property type="protein sequence ID" value="ODM95865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT48"/>
    <dbReference type="OMA" id="FQMVCLA"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009621">
        <property type="entry name" value="UPF0239"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14409">
        <property type="entry name" value="MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14409:SF0">
        <property type="entry name" value="PROTEIN MANBAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06783">
        <property type="entry name" value="UPF0239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="8996" checksum="DAE22FF5647F7211" modified="2016-11-30" version="1">MEVQEDVVDTFLRYGLFIGAVFQLICIGAVIVMPDNKSECCQDSDCSEDERSISDQGSPHISPHHKHHRQKRDKKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTF2</accession>
    <name>A0A1D2MTF2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000568">
        <property type="protein sequence ID" value="ODM96178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTF2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="400" mass="44737" checksum="68F78BB8564C3E15" modified="2016-11-30" version="1">MKSPLERSSNDSSIVNLITTDDLNKGNGHYADNLAFSIPEDVAFTNPETKHVFVYAPLTQTADDDGLNRSTKPFEKYTLSSSTIKKAALSGCALAATIIILYLWIHVKLVNPLIVEIFEIAPTTTTEKTVTSTIKILKPLKSEWKVEYNLPNGIPAIRMSAEEMKDITNIHCPSKTFALALYVDSNLELAETFLKTCGKNVAYFRVDGSPTISEIEQLKLYVPNAEKLELKANLKLEKGEQILDNPDFIKTKNSDDRIKTLEISGFVTFDDLTELVEVVPLAEELTIKGGEICKSLSRASSNSYIKSSKEACQITWPILQKLRIVETQDCRAMYDLIYSCWNMPSIETLQIRKSIINASNANYITGILDKNRITKVDFADNVCFDDTIQTVPFMCQASPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUW2</accession>
    <name>A0A1D2MUW2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000511">
        <property type="protein sequence ID" value="ODM96688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUW2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="8266" checksum="3A1301CC8086DB96" modified="2016-11-30" version="1">MMNNRLQSPAKDDLQTITSSSSFWIPFQMLRHPVSRHQFANLNKLVLLFAITCLIRMHAFTGKVSAEYGQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW99</accession>
    <name>A0A1D2MW99_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09351</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TM2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000454">
        <property type="protein sequence ID" value="ODM97333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW99"/>
    <dbReference type="STRING" id="48709.A0A1D2MW99"/>
    <dbReference type="OMA" id="ETFRKPH"/>
    <dbReference type="OrthoDB" id="5804096at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050932">
        <property type="entry name" value="TM2D1-3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21016">
        <property type="entry name" value="BETA-AMYLOID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21016:SF1">
        <property type="entry name" value="TM2 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="TM2" evidence="8">
        <location>
            <begin position="114"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="204" mass="22767" checksum="90AFC487C7C9104C" modified="2016-11-30" version="1">MPDWTECITFITLIIMIQPNMISPQKKDAQTSSSQSKDVIMNIVNHTVSCSQLRLGQYLCNNTNIDPVTQQPHGCSKETWTARITCTAVEGLICEETKSRNFEMDIPCKWTNGYKLDTALLMSVFLGVLGADRFYLGHLGMGALKFCTLGFLFIGQLVDIILLATQQIGPKDNSSFIIGYYGPGVTSIRANNLTYIVPRPDWFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWI6</accession>
    <name>A0A1D2MWI6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4789 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000444">
        <property type="protein sequence ID" value="ODM97420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWI6"/>
    <dbReference type="OrthoDB" id="6338576at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031993">
        <property type="entry name" value="DUF4789"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21177:SF4">
        <property type="entry name" value="IP06524P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21177">
        <property type="entry name" value="IP06524P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16033">
        <property type="entry name" value="DUF4789"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904659" description="DUF4789 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4789" evidence="2">
        <location>
            <begin position="86"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="30040" checksum="30A7C99480F85E3D" modified="2016-11-30" version="1">MCPSAFKLRASTTTITLFLFLIPLCSAVPVDLYHSGYDEIKRAPPQKIDSPGLCPENLNNDNITNFRWFRYHNETKKCWHIDQRGPCGYNMIFYRIGETEYGGCECNFYYRCARPLLYWPMEKRCYFTNEQGPCEQQDWLVVTEDLKPKCMPNPCIYNQTVQPSRKDRYWFDHGGECFMTLTRGYCSHSDETLYTKWDEYTPSCHIGRECNLRKVRGTANSRSFPSQNSCLPGQKLDSDGRCRKIIRISWWSVLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXF5</accession>
    <name>A0A1D2MXF5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 3A31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_09064</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000427">
        <property type="protein sequence ID" value="ODM97621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXF5"/>
    <dbReference type="STRING" id="48709.A0A1D2MXF5"/>
    <dbReference type="OMA" id="MIDANMS"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF104">
        <property type="entry name" value="CYTOCHROME P450 308A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM97621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="325" mass="37042" checksum="CE93C698AE83023B" modified="2016-11-30" version="1">MDCFDVPIGKTSIFEDMGKKFQFNLKPILLLKFIFIVTLPKIADMMKIEVMDTVPQNYFADGTVPESSEFDGKELDFLQLMLDAQEGLLKIDDDTNEVMNGTTEKNILNGASVTDKQKITFDDDDIIANSFGFDTTQSLLLFAVYQLALEQEVQEKVYKDVKAAVDANDGKISYDGLLNMTYLEMFLNETLRFFPPAGRTERICTKDYPVPGTNIVIEKGTLIAIPIYPIHRDAKYWENPTKFEPERFLVDRKSSRNTLSFMPFGHGPRNCIGLRFAMTEVKAVISTLVQTFKFETCLKTTIPMQFDSNSNLKPKYGMWLKVTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXL0</accession>
    <name>A0A1D2MXL0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">RuvB-like helicase</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_08907</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="LJIJ01000411">
        <property type="protein sequence ID" value="ODM97777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXL0"/>
    <dbReference type="STRING" id="48709.A0A1D2MXL0"/>
    <dbReference type="OMA" id="RTLPYNK"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140861">
        <property type="term" value="P:DNA repair-dependent chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060828">
        <property type="term" value="P:regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042127">
        <property type="term" value="P:regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 13 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 13" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="62"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM97777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="456" mass="50123" checksum="75896D75D5084FE8" modified="2016-11-30" version="1">MKIEEVRSTAKAQRISAHSHVKGLGLDENAVPHQEAAGLVGQEEAREAAGIIVDMIRSKKMAGRAVLLAGPPGTGKTAIALAIAQELGSKVPFCPMVGSEVYSSEVKKTEVLMENFRRAIGLRIKETKEIYEGEVTEITPHETENPMGGYGKTVSHVIVGLKTSKGNKQLKLDPSIYEAIQKEKITEGDVIYIEANSGAVKRQGRSDAFATEYDLEAEDYVPLPKGEVHKKKEIVQDVTLHDLDVANARPQGGQDILSMLGQLMKPRKTEITDKLRKEINKVVNRYIDQGIAELVPGVLFIDEVHMLDIECFTYLHRALESSLAPIVIFATNRGRCSIRGTEDIVAPHGIPMDLLDRLVIVKTSPYTKEEMLKILRIRAKTEGLVIESDALELLSETGERTTLRYAVQLLTPSAVTAKINGRTSITKDDVNEVAGLFLDAKSSAKLLSENDSKYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYQ6</accession>
    <name>A0A1D2MYQ6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acyl-aliphatic-L-amino acid amidohydrolase</fullName>
            <ecNumber evidence="3">3.5.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acyl-L-amino-acid amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08742</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.14" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000394">
        <property type="protein sequence ID" value="ODM97934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYQ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MYQ6"/>
    <dbReference type="OMA" id="KWTGKNQ"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004046">
        <property type="term" value="F:aminoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000019">
        <property type="entry name" value="Aminoacylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.900:FF:000001">
        <property type="entry name" value="Aminoacylase-1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000005">
        <property type="entry name" value="Putative Aminoacylase-1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.900">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052083">
        <property type="entry name" value="Aminoacylase-1_M20A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010159">
        <property type="entry name" value="N-acyl_aa_amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01880">
        <property type="entry name" value="Ac-peptdase-euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45892">
        <property type="entry name" value="AMINOACYLASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45892:SF1">
        <property type="entry name" value="AMINOACYLASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="11">
        <location>
            <begin position="195"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="11">
        <location>
            <begin position="556"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610159-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610159-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM97934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="764" mass="86372" checksum="EB36CA8A34EBF92E" modified="2016-11-30" version="1">MNDFVNYNINMDNGEHRAVTNFREYLRIKSVHPNPDYEGCIEWIKRQATEIGLEFNIVEFPKPAEFAVWLTWPAKTAALPSILLNSHIDVVPVDETKWTRDPFAAEKDSDGNIYARGTQDMKSVGVQYLEAIRNLKAKGFVPLRSVHVLFVPDEEVGGSKGMAPFVKSPEFAKLNVGFALDEGLTSPDEEIILTYAERAICQVKFTAKGTTGHSLILHENTAGEKIQKVINRLMEFRAQEKARLESDPELLLGDVTTVNLTMFGGGMQINICPTELSASFDIRLTPKWKKEELLRFLDEVCEEAGPEVTYDYVFQSLDYTAVTPLDDNNKWWNTFKSTCEDVGVKLKPIIMPGATDVRYVRQQGIPAFGFSPINNTPVLLHANDEFLNEAVFLRGIELSVLHDLKKTEQKTTWKMGEDIAVTNFREYLRIKTVHPDPDYDTAIEWLRKQAKDLDLEFNIVRFEPPNEFAVWLTWRGTDQSLKSILLNSHIDVVPVDPSQWNYDPFGAEKTPNGNIYARGSQDMKCVGVQYLEAIRKLKATGFVPLRNVHVSFVPEFRVTAKGKTGHASILHENTAAEKLHKVINKLLSLRESEKARLQSLRNPELGDVTSVNMTMLGGGLQANVVPPELSAVFDIRITPHWTLESMKKLLDDTCANAGPDVTYEYIQHSNITAQTVVDDSNIWWTVFKGVTDKLNLKINKKIFPAATDIRFIRQLGIPAFGFSPMNNTPVLLHDHDEYLNEAVYLRGVEIYTALLEKIISQPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0D1</accession>
    <name>A0A1D2N0D1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sorting nexin-11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_07948</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000330">
        <property type="protein sequence ID" value="ODM98729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0D1"/>
    <dbReference type="STRING" id="48709.A0A1D2N0D1"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901981">
        <property type="term" value="F:phosphatidylinositol phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043544">
        <property type="entry name" value="SNX10/11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46209">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46209:SF3">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="44"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="185"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM98729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="27401" checksum="A1FB213DE675C923" modified="2016-11-30" version="1">MDTAVAFNSSTDSRSVGVSSTRVMSNGTVFLVHERGSRRRIKLEVCQPVTITSKEGLGWTTTFTSYLIQIDTNHYAFSLPYSEVRRRFSEFCWLHSKLAYHHPNKIVPPLPRKTFIYATKFNGNVIEQRCIGLGKFLQRVMRSSVFLSDAALHYFLQTNLSIKEIEEKLEAEIPVRSIPISQLNKPKKRPKFSRSISCSSSDSTSSERSVSSSDGDCEREPAAGEPDSDGSSIEIESCDSFPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N252</accession>
    <name>A0A1D2N252_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07316</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000285">
        <property type="protein sequence ID" value="ODM99363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N252"/>
    <dbReference type="STRING" id="48709.A0A1D2N252"/>
    <dbReference type="OMA" id="PFNVQRF"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1400:FF:000003">
        <property type="entry name" value="Pyruvate dehydrogenase phosphatase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032503">
        <property type="entry name" value="FAO_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF15">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16350">
        <property type="entry name" value="FAO_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase central" evidence="5">
        <location>
            <begin position="396"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="GCVT N-terminal" evidence="3">
        <location>
            <begin position="454"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="4">
        <location>
            <begin position="753"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="924" mass="104644" checksum="31FD81430EB527BB" modified="2016-11-30" version="1">MNTCRILLQSTPLKQCPSRFFSKTQVVESLPKEARVVICGTGIVGNSVAYHLVQSGWSDVVVLDQDSRIGQGTSSYGSGTLALLKPVEEQKIITKSIALYKKLQAEGHDIGLVECGSLYLAQNRERMILFKRRVALNQPQGLQCKLLGPNELAEYHPLLYTADLQGGVFVEKDAVANPELVCDTLAKLAVAGGAKYIKNCVFNNLITHNAKVASVETSLGTIKCQFFVNCSGMWAWDLGQRSNPKIRIPVHAVEHFYLRTHPLVENLPQDLPTIRDYDSHIYIRKLKDNSFLMGGFEKNAKPIFTNGVPDNWRDCLYPDWDHFAPMLDDCLRRMPKLKDCELQTLLNAPDTFTPDGKWILGETPEVDNYFVAVGMNGNSLQGSGGIGHSLAHWIIEGEPDIPLIEFDIRRFVDVHNNRRFLYDRVKETVGRQYDILYPLQSEYQYARKIRCSPLYSTLQAQGAVFGTRMCFERPLYFDIDYKVGDPKPQMPKGTYWKPLFFDSLKEEYKACREGVAVIDMSSFTKLQIKSASDEAMEYLQRLCSNDIDVPEGHISPTGMQNENGGYENDCMLVRQAPNCFFMVAPTKQQKWMKRHMPEDNSVQISDVTSMYTVLLIIGPKSRELLSQLTEGQEDVKMHPFSYKTMSLGHAPEVMVLSVTNSGEAGYSLYVPSEYAVHLYDELMKIGKDYGIRNAGYLTLRFLRLEKFVPFWGEEMDSITTPLEIGRNHRVKLNKQHFIGKQALQTQHEKGVYRRLVHFTLDDDHDAENDVWVWGGEPIFRNGVYIGSTTSGGYAFTLERMVALGFIVNKDIKTGELLPVTQEYVMSKDALYQIDIAGRRFNVRQSLHPPRLPSPHNVHSRDYHPTLRDKSILQAKPFEATDIEISSENSGLLPYMIDNKGLQGSGTTSKYVPPELRLQNSAQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2D2</accession>
    <name>A0A1D2N2D2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sensory neuron membrane protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_07285</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000284">
        <property type="protein sequence ID" value="ODM99400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2D2"/>
    <dbReference type="STRING" id="48709.A0A1D2N2D2"/>
    <dbReference type="OMA" id="QYRQKDN"/>
    <dbReference type="OrthoDB" id="10024078at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF109">
        <property type="entry name" value="SENSORY NEURON MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="444"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM99400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="486" mass="54762" checksum="4A4A286E000E2A92" modified="2016-11-30" version="1" fragment="single">MKKPKTRCAIQIASAALVVVLFLRYGVTNFVLKTVVSSKIKLAPGNDVWNIWSEMPIPMYSKFYFFNVTNPDKVMEGAKPILKEMGPYVYQEHRQKIILESNDETVKYRPKITYMFRPELSYGSQDDKVTLLNVPYVAVAKIAWDVSKEPFMLSTLDDILSAKGESLFHTNRVREFLFDGFSIENYMELFSLPVEAFGVKTEIPARILDGDFGFFDDRNGTAEEIWTVGTGIRDKQNLGKIVSWNGKSSLDGWSDERCNKIDDSTDGTIFPPVADTSRILDVFHPDACRSLQMSYVGPGEFIEIPTHRYSFASNTFESLDLHPENECFCKETYEWCKKGGVFPLWPCVGGAPVFISRPHFMNSHVDYRKAVDGLNENGDYSSVIDVEPTIGLAIRADMKLQVNIELQSFGSMATFINVPNLMFPVFWMEETAELTEELAKPLKWLTIGLLIADSVIQLIVIGCLAIILIAVGIEAKNSNWLGKCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2W1</accession>
    <name>A0A1D2N2W1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metalloendopeptidase</fullName>
            <ecNumber evidence="7">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07087</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6 7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000269">
        <property type="protein sequence ID" value="ODM99608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2W1"/>
    <dbReference type="STRING" id="48709.A0A1D2N2W1"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811360" description="Metalloendopeptidase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="9">
        <location>
            <begin position="262"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="128"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="198"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="308"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="475" mass="53895" checksum="03B9CA664778A67F" modified="2016-11-30" version="1">MLVTNILTIFSVGLMTRVATQQPNQQHSFGVSPGSSFFYNNGVQNLNPQSQSSRINETLGSFIPPQLQLTGSHLSQANQHKKKFYQKGRLIRKHRDQRGRQGSNCLGVCTYIPDRDLCPTYLARETEPDDYDDDYDYSDESSGRRRRRRSIKGSNKNRTSPVRNTDLGFESSSSQAPSLHLVFPPLTMFAVSKGAIQSSNVTKKEKRKQTRAKPTRGKRPRPASSAARLRPPALEQEIIIRWDRVVERGPFIGGDIVVPDGVLLRPPNLRFTSRWPKGRVPYTIDQTLNDCRLDTIYDAMDEIEDLTCIRFVERNRERDYLSIRRAELGCASYVGMIGGTQQLNLSTGCFSKFTVTHELIHAIGMDHEQSRRDRSKFIEVDYDNVKRGKRSQFEVNPSHGGSGFPYDIRSIMHYSAFLFARDNCEPTIYPVDSDLDVCDLGIGNGKGGMTKCDAAKINKLYKCGRRYPKRCRVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3G2</accession>
    <name>A0A1D2N3G2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000255">
        <property type="protein sequence ID" value="ODM99780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3G2"/>
    <dbReference type="STRING" id="48709.A0A1D2N3G2"/>
    <dbReference type="OMA" id="FNTPHNY"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904974" description="Chitin-binding type-4 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="2">
        <location>
            <begin position="21"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="217" mass="23800" checksum="26F226D9589A14F5" modified="2016-11-30" version="1">MLKLTISLASLLAIVVLVNGHGRLWSPAGRGTLWRFPQFQKYNPERDYNDVEGFCGGFHVQYNENGGNCGVCGDSYSDPAPRRHEGGGLFGRGIITGNYSAGQIIEVQIDLTASHLGYFELRLCPQNNPLVPATQECLDQYVLELADGSGTRYPIPTFDAQLHTYSVKLPEGVTCRQCVLQWHYNTGNSHGYCSDGAYKLGCGSQEVFRACADIAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3U7</accession>
    <name>A0A1D2N3U7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="12">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_06754</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000246">
        <property type="protein sequence ID" value="ODM99933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3U7"/>
    <dbReference type="STRING" id="48709.A0A1D2N3U7"/>
    <dbReference type="OMA" id="EEFWRMF"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000016">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF5">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM99933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="606" mass="69357" checksum="9779BBD622FF1AA9" modified="2016-11-30" version="1">MRPLIGSNNYVKRRKAPEKTRSRSLRGTFDLATILILVFTIVPVSLQAFNIFSHSYDRLDQKYGSFTEKMRLEMLEEVKKMFYFGYDGYMKYAFPMDELDPIHCVGRGPDHENPSNININDVLGDYCLTLIDSLDTLAVLGNVSEFQRAIQLVIDHVSFDKENTVQVFEANIRLLGGLLSAHMLMEEDRFMFGDDLRPPWYNGQLLQLAHDLASRLLPAFQKSITGIPYPRVNLRKGTVDEGAETCTAGAGSLLLELGALSRLLGDPIYESMARRANRALWSARAKTTGLLGNVINAKTGQWVGRLSGLGAGLDSYFEYLLKSYILFGEEEDYQMFNESYSVIKQYLRRGRPQCNSGYGDHPLYVNVDMHSGNTYTYWIDALQASFPAVQVLIGDVEEAICTHAWYYNVWKRYGVLPERFNWQRLSPDVSFYPLRPELIESTYLLYRATRNPFYLHVGREIVQSLNTYAKAKCGYATVHDVLDMSLEDRMESFFLSETCKYLYLLFDTDNPLNNQFNKYLFTTEGHLLPIGEKMRSKPWETDVFPASATMSSLKEDESLFFRDKTPKLKTNATQPSCEAVDAARQYLLPLRTPYYLQLTESLGLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N526</accession>
    <name>A0A1D2N526_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Techylectin-5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06311</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000211">
        <property type="protein sequence ID" value="ODN00364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N526"/>
    <dbReference type="STRING" id="48709.A0A1D2N526"/>
    <dbReference type="OMA" id="HRNWVEY"/>
    <dbReference type="OrthoDB" id="7735550at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005577">
        <property type="term" value="C:fibrinogen complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005201">
        <property type="term" value="F:extracellular matrix structural constituent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034116">
        <property type="term" value="P:positive regulation of heterotypic cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.215.10:FF:000001">
        <property type="entry name" value="Tenascin isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037579">
        <property type="entry name" value="FIB_ANG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47221">
        <property type="entry name" value="FIBRINOGEN ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47221:SF5">
        <property type="entry name" value="FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="6">
        <location>
            <begin position="236"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="481" mass="52801" checksum="CABA843A42C7F7DD" modified="2016-11-30" version="1" fragment="single">PLLNALVNKLETLSSKLDDLTAAQTNIQKAFDTLESRFSLSATMDDVPQCGRRVDRVLRTLTPLVSRVEGLWSVVSGYSANPSLNSFSGVAGSAKQATNNVNLPPSQFLAPGDALLSESRRQERAISAIRSDLNAKSQQILSELGTVEQQLDVLQTNLKKPPPPGVDQSDLQAPADAQTNNDVTFQVVDEAFQTRPGNGSKIGNTSSGISALVFPSVKNKPIADATALDGADALLTGSGQTRSSCAELMMQPGQKRSGLYHIRLPGARSSFWQLLVYCDQDTTGGGWMVVQRRADFGEPRESFHRNWVEYRSGFGDPVRELWIGNINLHLLTNSEDQVLRIELEDFDGEKRYAEYSTFRVASEADAFRLEVGGYSGDAGDALSDPWYGAHGSAFSTHDRDNDRSSLNCASMLKGGWWWKSCGRGLNGLYFDSQQPDSALARQGIVWFRWKGWDYTLKKATIMIRPKSFRPGNFTAAFTSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5L5</accession>
    <name>A0A1D2N5L5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Organic cation transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000200">
        <property type="protein sequence ID" value="ODN00544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5L5"/>
    <dbReference type="STRING" id="48709.A0A1D2N5L5"/>
    <dbReference type="OMA" id="KAVHETH"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="109"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="589" mass="65671" checksum="BD1CDE4D3A9AFF34" modified="2016-11-30" version="1">MKLKSYDLSHIAHSDPDQQSGNTDNNDNTSVSQIVIHQQKKPKDSTSEPGERPVREVWHRRKSSWRDDNGFWTNNGRDESDSASRTKKPSLTAGSFEDILDRLGCFGPFQVITLLSYLLMEIASAFIVFIPIFVGTSPESMAYNCTTGASDEHFKVNETSNFIGSIRQMIDSPFHYKSIADEWDLRCEKAWISDVFTSCLMIGMIVGNLSVSLLADWYGRRQTYLLILCIMFFGTLMSALSPTIYIYAVARFIAGIGFCGCINVSSMAVMEFMTPKWRSLSNCLGPMGEGVMLLSCIAYFIRPWRLLYLATAVPYVLIIPIYFFLPESPRWLIRNKKLKEAHDVLGYMAKINGKEPISYDLLEALQKQEEKETESLKAKKLSYMEFVRNKSLFVTSLYLFAIWFSWNVAYYGISYNIRNVPGNLYFNVILIGLANAVGQRISMPLSDWVGRRKAVLCGMVLSAVFLVALAICFLTISVGSYLILIVCFVGLLGMSCTRAATRLLSGESFPTAVRTMGLGVGGLGANIAGVVTPQVAYLGSRWPALPFFIFSVVSVLGSLVVFMMKETKDTPLSDNVKSGNKNKGTNGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5M2</accession>
    <name>A0A1D2N5M2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ras-related protein Rab</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The small GTPases Rab are key regulators in vesicle trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5M2"/>
    <dbReference type="STRING" id="48709.A0A1D2N5M2"/>
    <dbReference type="OMA" id="NNFIGWT"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045335">
        <property type="term" value="C:phagocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090385">
        <property type="term" value="P:phagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04107">
        <property type="entry name" value="Rab32_Rab38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002133">
        <property type="entry name" value="Ras family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030697">
        <property type="entry name" value="Rab29/Rab38/Rab32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF42">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7L1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="25025" checksum="4A9C83AA4215CC34" modified="2016-11-30" version="1">MADPKETFVEDPPKIMSEKLFKVIIIGDPTVGKTSFVQRYVQGSFKRDYKGTVGVDFALKVFKWSESQTIRLQLWDIAGQERFTWMTRVYYKDAHGCIIMFDLTNRNSFQNTIKWKKDVDSKCMLPDGSPIPCMLLANKCDLSSRQVDQMEIETFYKENNFIGWTETSAKEGLMVNDSMRFLVEVMLRQSGSGTNGFSNGNGTDRLHLKSALPTSSSCSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6L9</accession>
    <name>A0A1D2N6L9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ras-related protein Ral-a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05779</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Lipid-anchor</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000182">
        <property type="protein sequence ID" value="ODN00910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6L9"/>
    <dbReference type="STRING" id="48709.A0A1D2N6L9"/>
    <dbReference type="OMA" id="LETVVIM"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="19405" checksum="B9645774CC39DF7F" modified="2016-11-30" version="1">MKTKWKWNGLETVVIMVILDGEEIQVDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEETSLDSCHELREQITRVKNSDRVPFILLGNKSDLDERRKVPRPNAEGKSKSWAVPYIETSAKTRENVDKAFFDLLRIIRDGKQAEKTSGKAANGQTASSGPQDSPRGKFCCGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6P2</accession>
    <name>A0A1D2N6P2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05772</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000182">
        <property type="protein sequence ID" value="ODN00901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6P2"/>
    <dbReference type="STRING" id="48709.A0A1D2N6P2"/>
    <dbReference type="OMA" id="ETCVTAV"/>
    <dbReference type="OrthoDB" id="6506078at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21453">
        <property type="entry name" value="DLC-like_DNAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000002">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 12" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00057688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12295" checksum="8A827CDC55D17A8D" modified="2016-11-30" version="1">MQAAAQPQAEAEQETEKKAIAAYPIVRYTDVPEETKADIVDTITGAVERFGADYDLAAKLIKEDMDRTYGPHWHAVVGESFGYEVTHQNNHIMYMFFLGNLGILVWKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7B1</accession>
    <name>A0A1D2N7B1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc-responsive transcriptional regulator ZAP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05533</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000169">
        <property type="protein sequence ID" value="ODN01144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7B1"/>
    <dbReference type="STRING" id="48709.A0A1D2N7B1"/>
    <dbReference type="OMA" id="HCTICAR"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="426"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="180"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="222"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="281"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="526" mass="60661" checksum="615A1B63049D52FF" modified="2016-11-30" version="1">MAYPSSSSSKLREYLESPSSCQVTRFMGREAYNGEDEHITVPITSIPYFIGSEENLPKKWKQHLIPVTPWRQRIPTRIHLSSSPLPHYPVLSNQVAEQETIPTPFTQPVQPSNSEEDIVVLAEFPKPSPNDEYYTEDEYSEEEGEGNNGDDNAEMPRDPTTEAVKETLEYILSMVCENEEPNGEVEKDDRSDSPFQADNDSSSEDSVSRASCIQWIGKRKAHNSGIDPNLQDKKKKVCADPSQNLVRDQDPKNNNGTPLGSDNLVTSVEVYKSMRHVQGKEGVKKKSYKTQRRRQARKGCSSSSSNTITNGPAMEIQRHLQIPFNPMRPCCWHPCCIFMRELIRLMPWWRAHYQFEDLLKIYYAYCQIQIPIGFTDPPESEWTVAKVYHVNPTDGTLRYKCKNCEGTVEHRSSKRKRLLNFGRLNYECGLCHRKYITRRQLRLHSMRHSKKTHACVYCDKLFLTQGELQNHINTHTGEKPFCCPICFQKFAHSSRYYGHIRMFHKRYDCEGCFYRTCAAAKADEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7G6</accession>
    <name>A0A1D2N7G6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Decaprenyl-diphosphate synthase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000166">
        <property type="protein sequence ID" value="ODN01218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7G6"/>
    <dbReference type="OMA" id="DYFAIRC"/>
    <dbReference type="OrthoDB" id="8251390at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN01218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="51029" checksum="3D11DCFD540229A8" modified="2016-11-30" version="1">MILSKLVDITCASTSKIAQRYFQTVRSVQPETTAGIVQGIGFESIALPEKKIPPEIRREAGIADILQQVEALDGLPPIPSHIEHLVGRATKGKSYQNHILSQQKAKASSLNKDHDGHLNYPKQKYDVGGIDIAEKTQLILQSPHPVRYVIEREVHKSQQGFHRRLPSYHTWIMLFGRSLMSNQNRSESAYDRLLNHVANASDSGMFSSDIHQTILDIPDEHPSIGNCSAQLHMGNKYAVLVGDYFAIRCLYNAEKTKTNSVMVAITEGVEEFTCSFGASLLDKTVGYPQLLSPNASVLDWILHSQKAFGYFRGGLYAALSLQMKPNDRLKVERQMASLVSNLSLFLKAAAEMEALQEANSFVPSPFLLTSLPAVLYQSEHPHMFADLRKRGYELDNDYIRELQTIICRSSTSQRARNLITDFATETKQAFHHLAKDQYYTNVFDSLIDAVKDECV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAC6</accession>
    <name>A0A1D2NAC6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein FAM136A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM136 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAC6"/>
    <dbReference type="STRING" id="48709.A0A1D2NAC6"/>
    <dbReference type="OMA" id="NRCGMTC"/>
    <dbReference type="OrthoDB" id="9975421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008560">
        <property type="entry name" value="DUF842_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096:SF0">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05811">
        <property type="entry name" value="DUF842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16456" checksum="9D0D6D9C0607F286" modified="2016-11-30" version="1">MSVSADAMDAQRRVQEEMGEVINEIDKSHLRRIQRQMHECAAKCCANEVASLEDTHGCIEKCSASVHVAQNYVQKEVGGFQERLQRCVLDCQDKSRDKLSTNASESEMLGLKNEFEHCAIRCVDDNLKLLPTLLKRMKASLDKASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBX6</accession>
    <name>A0A1D2NBX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Glutamate receptor ionotropic, NMDA 2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_03902</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Postsynaptic cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBX6"/>
    <dbReference type="STRING" id="48709.A0A1D2NBX6"/>
    <dbReference type="OMA" id="WIVPEIV"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000157">
        <property type="entry name" value="Glutamate receptor ionotropic, NMDA 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001508">
        <property type="entry name" value="Iono_Glu_rcpt_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00177">
        <property type="entry name" value="NMDARECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="9 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0628">Postsynaptic cell membrane</keyword>
    <keyword evidence="10 21" id="KW-0675">Receptor</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0770">Synapse</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="686"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="887"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="19">
        <location>
            <begin position="493"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="20">
        <location>
            <begin position="505"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="747"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="788"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="804"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODN02749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1142" mass="129543" checksum="808082025A917B03" modified="2016-11-30" version="1">MILPHSIFHRKDYLKSINVALTNFKPKNGTEEMFSRFFNLDPLKHVLVRLITISPSPQDILSTLCEAFLTSNVSAIIYLTNIEKYTTSTAASQYFLQLAGYLGLPVIAWNADNSGFQRRATSSSDYNSEMVLQMAPAIHHQAAAMLSILTRYNWHQFAIVTSQIAGHDDFVQAVRDKVVESQFKFKFVELANVLVVTEQDLFPLVDSEARILLLYCTKEEAKWIMRAATLFGLTGAKYVWIVTQSVIGDSLTLTDVSYQEKESQELPVGMLGVHFNTTIEALKAEISNSLRVFANGVLDFRNDARNHRITLTPNVSCDGQGEYAKWREGDHFYRALRNVTIEYPDVSRPPLRFNPDGTIMNVELQIMNLRPTSGISEKNLAWEQVETVLFRFFSIFNTLNRAVLGLQIGSWHSWKKDDEDTQLDIKDIIWPGKSHKPPDGVPEKFHLKITFLEEAPYIRMTDPDPITGRCSPDRGSLCRINNNSQVDYQHGPQSRSSNNTVENLAFLSNCTNCRCCSGFNIDLLVKFAEDIGFTYDLIRVADSKWGTYVGHKWNGLIGELINRKADVALASLMINSEREAVVDFSVPFMDSGIAIMTAKRTGIISPTAFLEPFDASLWFLVCVVGIQVYSLFIFLFEWLSPLGFDMKKYPSPGSRFSFFRSCWLVWARLFQASVHVDPPRGFTAKFVVHVWSMFAVVFLATYTANLAVFMITREETHQFVGIHDQRLSNPMSIKPSMKFATVMNTHTGSLLAKHHPDMFVHMKQFNVATVSEGVNAVRRQELDAFIYDGPVLQYEVLQDTSETCKLLIEGSWYAHTGYGIAFPRNSKYLPLFNKLLMEYKENGDLERLRRYYFTGPCAAEQGRQSQPTTTVAKFNTFGTGPLALEQFLSVFLLLGIGVLVGTVFVFCERAYANCIVSRVFDNSDQSQKKPVNVAENKNKKPPPACLQLLSQNMGLPYSRTFYRAHKRDSNIKLLDHITSSFTIYDNPTTQHTITDYYHGFLESFVLRKMITCNDPICQRNFVKLENELKKCLIRLRQIENWGRLYDLNEIGRRSTIKQSSNALMRTRISTIERNHDEIVGKRICGDYSDYSIFSGTAGGVAVVSAAGERNRVFRDQVIGGKNNDNEEIGNQIIKVAEIETVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCL2</accession>
    <name>A0A1D2NCL2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative odorant-binding protein A10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000090">
        <property type="protein sequence ID" value="ODN02997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCL2"/>
    <dbReference type="OMA" id="QIMCIFY"/>
    <dbReference type="OrthoDB" id="6355718at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2080.10">
        <property type="entry name" value="Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005055">
        <property type="entry name" value="A10/PebIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036682">
        <property type="entry name" value="OS_D_A10/PebIII_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11257:SF11">
        <property type="entry name" value="CHEMOSENSORY PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11257">
        <property type="entry name" value="CHEMOSENSORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03392">
        <property type="entry name" value="OS-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100910">
        <property type="entry name" value="Chemosensory protein Csp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="22102" checksum="130AE500AA83ECAF" modified="2016-11-30" version="1">MKLTVGGSSVARMIASSAFVILSVKILVCASYRGVLHPLTYQRQIDYLDVEQYFRNSRLMRIQIMCIFYDEPCDLVGRWLKPRLFPALFGDCPACTEYQKEKLPQWLLIFADKYPVMFRAVVAQFLMDQGYPVPKEEIPKIQRAFGFRDTRKILNPQSVINASVVAPIGARKDTGPALISYFGRRRTTKPKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCW8</accession>
    <name>A0A1D2NCW8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000087">
        <property type="protein sequence ID" value="ODN03104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCW8"/>
    <dbReference type="OMA" id="LRESPMN"/>
    <dbReference type="OrthoDB" id="10377381at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905370" description="Ricin B lectin domain-containing protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="20196" checksum="0CD7ED0169C5A4D6" modified="2016-11-30" version="1">MTRNHIWAKNSASRCAVVLILISIWSVSNTNAGMDEFLRDAMYSIQSASDRGYLTLRESPMNTYKIIQPEPWGNEKSQKWMVFDFQSIGLYDFTPVMFNTTDNMVTYEASKNVYTFKRQWKVTLVTVDKYQIRNPESTLCLTNIGSYKEVTEKTCHPRLPLNQLWKFRMHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDV0</accession>
    <name>A0A1D2NDV0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF243 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDV0"/>
    <dbReference type="OrthoDB" id="8030796at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040003">
        <property type="term" value="P:chitin-based cuticle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004145">
        <property type="entry name" value="DUF243"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31927:SF2">
        <property type="entry name" value="FI07246P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31927">
        <property type="entry name" value="FI07246P-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03103">
        <property type="entry name" value="DUF243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00690">
        <property type="entry name" value="DM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF243" evidence="1">
        <location>
            <begin position="45"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="191" mass="21257" checksum="E1EF3613A0226E28" modified="2016-11-30" version="1">MKVEGSSIHSVLPIASSILNLGKTSYSSHNEVNTINGGPTTTRIAGIKKYVTIHTPPSRFDEPQQPKVIRVGGEPEKHVNIVFVKLQSPTSSKKTEVILPEPPQHKNIVYILLQKQEPLDNIRIVRPPAKRENPEIYFIRYRSPNSNELPASNVIENAKQPASIIGATFTEAPIYSSFSTAYGLPMKNYRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE71</accession>
    <name>A0A1D2NE71_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein misato 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03134</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the misato family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000070">
        <property type="protein sequence ID" value="ODN03551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE71"/>
    <dbReference type="STRING" id="48709.A0A1D2NE71"/>
    <dbReference type="OMA" id="FVGSHIW"/>
    <dbReference type="OrthoDB" id="271881at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049942">
        <property type="entry name" value="DML1/Misato"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029209">
        <property type="entry name" value="DML1/Misato_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019605">
        <property type="entry name" value="Misato_II_tubulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391:SF0">
        <property type="entry name" value="PROTEIN MISATO HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10644">
        <property type="entry name" value="Misat_Tub_SegII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14881">
        <property type="entry name" value="Tubulin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Misato Segment II tubulin-like" evidence="5">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DML1/Misato tubulin" evidence="6">
        <location>
            <begin position="153"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN03551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="574" mass="64280" checksum="1B96496017958A7E" modified="2016-11-30" version="1">MGQPGEIITFQVGNYANFVGAHFFNLQDPHLNPEHETDFCHRVFWREGQNFQRQKILTPRVLMFDLKDNWGNAFIRNSNDVSEPGIQPGTFAKSNQPVKQNRVDQVEKNISWDGKVQTVVLRNDSSDSDEDLDPLPGTHKSANAGKKKVKLGPSDFSSWGEYAKWRLHNADKAAFRIPNYMYNAGSEELVSYGQGLDVYNKIQENVEDGIRHYAEDCDHLEGFHMLVDEYDGFTGIAGGILEHLGDEYDKKACLGLGLNHPFPDNEKWSKRRTLKEYKIRISNTAQLWGSFTNHSRVFSSLGVTEDIFSMNPSSKKFTSVVQDCTSPYISSAILAAALDSLSSPYRLHSPSFPLHEMTSVLNAFGHKMTIIGSSTPFPMGQQTLFSALNKDGFSSLNCLTPNVSLDLDTALGNVFVTRGINQDHVMSKSECREYKHADINSVTSCLELFCQESYPRSVHVIKNLSNSFKMRYPFPKLYDDVYLDTHSTKKQFTNPQVPCWFLPALTTAHNTPGTSKILERLISTIGGGTGGSAMKLKTFYEPSSATCNSSVVEFEDFADCVTELCSLKDTYSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEF0</accession>
    <name>A0A1D2NEF0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDENN FLCN/SMCR8-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SMCR8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000072">
        <property type="protein sequence ID" value="ODN03475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEF0"/>
    <dbReference type="STRING" id="48709.A0A1D2NEF0"/>
    <dbReference type="OMA" id="MSTDYQV"/>
    <dbReference type="OrthoDB" id="2289278at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032045">
        <property type="term" value="C:guanyl-nucleotide exchange factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31334:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31334">
        <property type="entry name" value="SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="7">
        <location>
            <begin position="67"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="380"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="756" mass="85142" checksum="DD72020173A709B5" modified="2016-11-30" version="1" fragment="single">MTVTAGPQQLEGTAVTRSGANMSLTYSDFLYARNDYTDDFDDGSREVRRSLPSDFKPIQETKVPLMQNAEGEDHDFIVIAEFSELEGPIPLCTIPNDAADKTDIKMNDFVVHLMSTDYQVNTVGQFRICQDTQVMRKNVFPDVHVFMQYFTLYDIKARGFVRPFCLGYVTKDHTKLDKYVNFLIAEFAKVTAVLEESNRKWFSQELKLYLEKLQNAKESYIQEYNVEPGNEKSQFEEFVDADNVSLDQIAHQYSEIHNILTIVQQSFVDSSSSSSDVILFAERHSDSTLINFLKRNGIISKSSPTASSESLNIPLVHPLRPKGEPLRPLTVLGQHGSVYLVAKLMQIYSNCKVDVLFTEMTEATLYFARHFENLRLQTAADPAPASPGKSSGISSSDDASFSDDSRHSCGELSPSIQDTALLRNMQTKELYQLVEKLHVYVPVISDNKSGSYHTVSEEESDANFPTQEQQCGASVLESTIDTGIDMPATSHKSEVDPWDNLKMSSLHSFSSDEELSLGSLPFTHGTSEETILKESWWIHASKKLVRGIPGYGLANFFRRYHEAAHHVLYSILLGRPIIICGEEKLSRKIGRIITALIPLVPAISKSSWKLLRWHRGILVQAHIESYRIIGLCIPEKLEVHDLIPPRLVTLVTILSADKKCILGGPAYSGDLLQNFEKNYQKHFYSSDVSLLSYIGGIYSDIESKVYTYKSLIHKYKSKSSNNVHVLFKELNLRASDIEIIKYLGNLISDPSDCVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF81</accession>
    <name>A0A1D2NF81_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF81"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="116" mass="13045" checksum="21FCF8A13061795C" modified="2016-11-30" version="1">MAGGLFGIPKKIINFIRESGLYILFIPLLIILPLLMLAFNAGKLIGGLGWGWGRSLSTVENGIVGYFKSPAWQKVAETLMDEHVFDRVMKSLEDFRKDCVVELLRLETQTPSFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFE6</accession>
    <name>A0A1D2NFE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFE6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905491" evidence="1">
        <location>
            <begin position="22"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="90" mass="10217" checksum="7DF774D832965DAB" modified="2016-11-30" version="1">MNSKCFAVVIVLLAIGTTVHADDDDYFYMAVCDSRCDVGNRLTPFAESCDDCCRMRGFRKGKCGGFGWQYCKCKRMSQLRNLFNAILNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFL0</accession>
    <name>A0A1D2NFL0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable U2 small nuclear ribonucleoprotein A'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02644</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFL0"/>
    <dbReference type="STRING" id="48709.A0A1D2NFL0"/>
    <dbReference type="OMA" id="PNYREYM"/>
    <dbReference type="OrthoDB" id="433501at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000026">
        <property type="entry name" value="U2 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044640">
        <property type="entry name" value="RU2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003603">
        <property type="entry name" value="U2A'_phosphoprotein32A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552:SF6">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00446">
        <property type="entry name" value="LRRcap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="U2A'/phosphoprotein 32 family A C-terminal" evidence="10">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="267" mass="30269" checksum="0BD244DAF16D08C0" modified="2016-11-30" version="1">MVKLTAELIQNCQQRINPVKDRELDLRGYKIPVIENMGATLNQFDTIDFSDNDIRKLDNFPLLPRLKGILMSNNRVVRIGDCLPETISNLETLILTNNMIQDLAEIDNLSQLKELKHLSLLFNPISTKEHYRAYVIFRLPQLKVLDFRKIKQKEKDDAKTFFKSKKGKEIRKEIVSNRSTIDDDLDEVEEPTVTNGRGLKVTPARRAPVAGERSAEVNNAIKEAIRNASSLEEVERLQQMLRVGQIPQSNTNEGDGAAAGEEGMDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFR1</accession>
    <name>A0A1D2NFR1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFR1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="19284" checksum="E144194C0D3BC710" modified="2016-11-30" version="1" fragment="single">SGVVLSKQKILRRVLRQRRQRPVTKKGKKTNAAEPPSPPHSASGDNANEVPEINQPLQNDDAVVSSSCDSFWANMFAPGVLPLADPLVTSTTSDEDDFYPLPRTPGNSPSPSDSPYSFIPYSPISPLPASSPSSPPSWSDLFNVTGSSDAIDLPLTPDFLRHHHDDDVELSYEDMRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHV3</accession>
    <name>A0A1D2NHV3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHV3"/>
    <dbReference type="OMA" id="NHLGYFS"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905579" description="Chitin-binding type-4 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="2">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="211" mass="22577" checksum="1EC198B7CC25B140" modified="2016-11-30" version="1">MAKFAIALIAALAVMSTVSAHGRFMKPASRSSVWRVPEFASQNPPANYDDNQLYCGGVHQADDPGTNCGVCGDPLSQGAPRDNELNGKYYKGIITGRYTAGQVIDIEVDLTTAHLGNMEWRLCTNPQSENQACFNQHVLQLANGSGTKLAAGPTGMPRTQVRLPAGVRCDHCVIQWNYRAGNGWGQCEDGSQGPGCGPQETFRGCSDISIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIE2</accession>
    <name>A0A1D2NIE2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIE2"/>
    <dbReference type="OrthoDB" id="10036174at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049885">
        <property type="entry name" value="MTCL1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15742">
        <property type="entry name" value="GIRDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15742:SF5">
        <property type="entry name" value="GIRDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="457"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="506"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="577"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="296"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="517"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="585"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="703"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="735" mass="82900" checksum="6252B61988CFC1CB" modified="2016-11-30" version="1" fragment="single">KELRALRETFNNRQDTWIKEKLALQEKLHDAELSAKKLMSIPGDGESTKLKNMLNETTKDLDAKTKEVDNYKDQIHHMQRENDELRRKLEDFDKVAQVHIRSLAPEPSPKSDKEMKELRERYKNTYNISFLELEKLHRNEMAQIKMRHDQALAVKTEEITTVQQQLSRAKRERDTFRQMVDSAQRAIAELKSRGGSSTRGSVTGLEEAATGAQAAVSGLQERITALEDDLTEARRDTSRQKTEFVTEKSGWEMKVAEMQQKINELEEERLLSGMGRVRGASAIGRTKLELAWQKEREEQQRRLKEATTLARDLKTTLLEIEREKDRERMEAKRRFEQLKSSLEEEQTEMKRKVESAQTDLLELRDAHAKLRTANEKLRKDRERLENQREAQIKRELEQKKVRSEKDKLLDQIISKLAALNPTASNSNLSQLPPKLNAAEILHYLQNMREIEEPDDLLNPKEKKRGHFKRAASVGDTEGSELPKSRESLVSMPASYGMKSYGKQQQYMGSVSSSTLTLPSRGRGPSLSSSGTKRISSNMSDGGGVSSSPFSPQGTLHRKALSLDQSVSMPDEQKIWKGGSEAGSAGSLTSIDGQFSRGSSMERVSTLSTKTDKSKTGTLVGKVKKFVKAKSIEETPAAEKLMIGGSQAGSDLSLNSDFEGKKSFTDKVKGVFKRSTRSPSVERRLPGTPMTSSLQLQAPERPSRGNTPTRETTPGASQQRPLMPSQQRPLMPSTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIQ1</accession>
    <name>A0A1D2NIQ1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_01535</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIQ1"/>
    <dbReference type="STRING" id="48709.A0A1D2NIQ1"/>
    <dbReference type="OMA" id="NHIACIM"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF285">
        <property type="entry name" value="V-MOS MOLONEY MURINE SARCOMA VIRAL ONCO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="271"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="112"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN05153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="547" mass="61586" checksum="C921614FF9B08589" modified="2016-11-30" version="1">MASVAKETLSPLLRSTSARRRSLELCQQLGSHLLSPTAATLFSSFSSSRSPQNHSSSPKPQSSPFRKTYTLSKQFNLYNDKTDTSFSAYHSRRRASDSSWIDNLPKLESFQDKEEQKYEKRRHSLTPQHPTSSLIKGKRKSNEWDDDDDNDLNSAVDEDWVVSRDNKDVGKAHPVIVTCNIIPPSPPQAARDEDIPTLEPSLYHTNCSDISESAPHDETDDANSYGQHKTDFHSIEFPSGLTRTRKSSAGEKYDLDENLLSLVTMRWNLSLNPEELLGKGSFGTVVTGLYQGNQVAVKVLKTTTLQRKASVLGERNALDLPPHNHIACIMDIFQVGPERTLIIMEKMDKGNLFSLLNNSDFTMNCSVAIKISKQIALALIFCHRQGLLHLDVKPQNILVGHDNCCKLADFGSSKKIGDLQSSYKHLQLEGTIPYTAPELFKGSQPTEKCDVYSFGITMWQIITRELPYQDENEHAVIFQVVSQGLRPNSGSNSDSIACNNKNKKEIQSTQKYAQLYEETWDSEPKNRPSMTDIHKRLLQIQFMDTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIR8</accession>
    <name>A0A1D2NIR8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">A disintegrin and metalloproteinase with thrombospondin motifs 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIR8"/>
    <dbReference type="STRING" id="48709.A0A1D2NIR8"/>
    <dbReference type="OrthoDB" id="9942326at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF247">
        <property type="entry name" value="PEPTIDASE M12B DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0401">Integrin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905631" evidence="3">
        <location>
            <begin position="22"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="4">
        <location>
            <begin position="291"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="571" mass="63212" checksum="575553B02A5DD230" modified="2016-11-30" version="1">MTASACGIVCLLRALFFIILSARISHQFTLTGTYSDAEFYQEQSLEWEDIEVEFLTNVKGTKLHSNDFHVAKVTLPTSKTVSYTMHISKTEGLFHPDHLGITPDETENLKCAYSGTITENSESLHPKSGLVSLSSCHHEQGFEGLVLLPDNQYYIKPKLSPRFAKRSLTPGTKQKVPHKAFKVNSEKNPFKAGNVDVVLIASPEEVKDALAKSNSNIDALEDEEVAEDLSPAQHEMDSESIDISETFHEDNDCVGSNCNFLPPSPIALANRKKRPNKASQSTTSSSSTPPRVVEIAVFVDEKLFKVWEGRYPKETKTSLNQYVLAVINNMNSLYKQPTMTEKISFRLVHVEIQTQKPSYMKDYSGAATKYLKSFCEYAAEKNQMGSLWDHALLLTGWDLSEGGSSATAGIAWFSTMCINTLSCSLIEGSTFGFTINRTLSIIIIKEIGHGLGMDHDGQSPRNTKCDANSYLMSPTTGGGKTDWSKCSVQNFKDFLSKGYQGNPSPRCITKKGSKAGSPIQFKSIKLPGQQFDSNAQCEADCKACKPYITSAAPYNVRKYVVYSMLKYLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJY6</accession>
    <name>A0A1D2NJY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative defense protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJY6"/>
    <dbReference type="STRING" id="48709.A0A1D2NJY6"/>
    <dbReference type="OMA" id="NICTSME"/>
    <dbReference type="OrthoDB" id="6418377at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08544">
        <property type="entry name" value="Reeler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4060">
        <property type="entry name" value="Reeler domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051237">
        <property type="entry name" value="Ferric-chelate_Red/DefProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002861">
        <property type="entry name" value="Reeler_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042307">
        <property type="entry name" value="Reeler_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45828">
        <property type="entry name" value="CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45828:SF33">
        <property type="entry name" value="DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02014">
        <property type="entry name" value="Reeler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51019">
        <property type="entry name" value="REELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reelin" evidence="1">
        <location>
            <begin position="11"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="19942" checksum="6D38D74C759918C5" modified="2016-11-30" version="1">MGFKVNIVGIIGTILVGYVSCYPNYVPNSPDVCSKMIPGHGPRPQTTPSPYEIVLNKQSVFGGNNLQVELKGKNGEKFKGFYIQARDQDGSPIGLFQSPNENESKAHTCFGVKNNAIHHTNRNDKESITLYWKAPEAFVGKVKIVATCENYKTLFEKHTLGFRGFSKPPGIGLGTIKRKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL68</accession>
    <name>A0A1D2NL68_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000015">
        <property type="protein sequence ID" value="ODN05845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL68"/>
    <dbReference type="OMA" id="GDSRICT"/>
    <dbReference type="OrthoDB" id="10476986at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905713" evidence="1">
        <location>
            <begin position="27"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="133" mass="14634" checksum="9A5BFAFF3FC84329" modified="2016-11-30" version="1">MTRLKHLTLVSFVIIVLISFFHTCSSQRPLDANDVYTFCASGRARGDIAMCKGYCADSNTRCSSETGVCGCTTTKLISNANANFSCRPAPSRTRCSNACKTFAAIETFRRGDSRICTSKSDTRIMCFCMPRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM30</accession>
    <name>A0A1D2NM30_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM30"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905747" evidence="1">
        <location>
            <begin position="17"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="8180" checksum="0B554E49EF8E0BD9" modified="2016-11-30" version="1">MKHFIILFALVAAAYAGVAYHGGILTSTGYQAPSLHAPWASSVDTGIRRFGSTAGYIAAPAYYATAAIAAPAYGHHYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMH2</accession>
    <name>A0A1D2NMH2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nuclear distribution protein nudE-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00562</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nudE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMH2"/>
    <dbReference type="STRING" id="48709.A0A1D2NMH2"/>
    <dbReference type="OMA" id="MEENSIN"/>
    <dbReference type="OrthoDB" id="5877028at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051642">
        <property type="term" value="P:centrosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007100">
        <property type="term" value="P:mitotic centrosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="10">
        <location>
            <begin position="140"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="269"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="35"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="34048" checksum="2B81882F594EC59C" modified="2016-11-30" version="1">MEDEDFDMTNVPNFTSPQEEAEFWKKKALACRKGLDELKKDFEEYQEDSKTLEVELDTQIKLTEQKNKDLTACISRIQNDNENLRSRLEQMNAEHNARMAEWSAEVTSFRKTGDEINTYVRELEQKNDDLERANRAAAMSIEDFEVKLNLAIERNAFLESELDEKENLKSMVQRLKDETRDLRYELQFTKRQSDKVVDSNKLEATPPSTPPYNLAKTHQANLSTPTSSRMSPLSIVNDLLRKVGALETKLQTYHKKDEANIKKLGRSVDSKNHQNKAHKLPRGVSSPAVQEIIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMX4</accession>
    <name>A0A1D2NMX4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ subfamily C member 5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_00042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMX4"/>
    <dbReference type="STRING" id="48709.A0A1D2NMX4"/>
    <dbReference type="OMA" id="CKALVIC"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051434">
        <property type="entry name" value="DnaJ_C_subfamily_member5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027:SF7">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="16"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN06633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="21943" checksum="7C65EA3C5D0DB97C" modified="2016-11-30" version="1">MAAAFGNRRFSDAGTALYELLELEKGANQDDIKRSYRRLALRFHPDKNPDDNTAADKFKDINKAHKILSDPTKKRIYDEHGSLGLHIAESFGEENVKYYFIFSSWWCKALFGVSCILTGCYCCCCLCCCCNCCCGRCAPKIDEDDIPNAEDLAAEEEADNKDGGASAGSPITAQPQPQLHQRKLSHRMVTVTLVPHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN05</accession>
    <name>A0A1D2NN05_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synaptotagmin-16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NN05"/>
    <dbReference type="STRING" id="48709.A0A1D2NN05"/>
    <dbReference type="OMA" id="QDDHIFE"/>
    <dbReference type="OrthoDB" id="5978493at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08389">
        <property type="entry name" value="C2A_Synaptotagmin-14_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08408">
        <property type="entry name" value="C2B_Synaptotagmin-14_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000062">
        <property type="entry name" value="synaptotagmin-14 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043541">
        <property type="entry name" value="SYT14/14L/16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46129">
        <property type="entry name" value="SYNAPTOTAGMIN 14, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46129:SF2">
        <property type="entry name" value="SYNAPTOTAGMIN 14, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="259"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="412"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="551" mass="60159" checksum="2BFBA2510E098341" modified="2016-11-30" version="1">MTFQISFPKYKENNAMEIFTLESLADSFYDHYSKTIILLRSATLGARIAGDSTDLISLAEKGKVNGGSSASSTSSNGSADDDPNHHQHNTQQGSVIRHPQPPPSSSSSASVIRTGVGGDSSRNSNNDTTTNTPQAHCSSSVPPQHHHSASSSQLLISSSSASHPHSSAVVSTSLSMHHQQALAIASTSSNFRRMMMPPRTKSLDSESPPPSEQGLSTYGDSIADQDDHIFEVEEISLVEGDLGMVGDSSRVTCPTSPVQCGNVEVGFDYDAAARKMTVHIIQVRGVPPKDIGGANNTQVRVVLLPGRKQKHKTKVRPGENPSFMETFVFTKINPEDVSSLGVRFRLYGCERMRRERLLGECVLEFGSLHLELETTIWLNLEPRYHLSWDSRSETGSLARSDSASSTASIQSGIPELLVGLAYNGTTGRLTCEIIKGSHFRQLAGGRAPDSYIKLVLVNTNGQEMGRAKTSLRRAQSNPLFKETFMFQVALFQIQEVTLLVSVYGRKGVTRRELLGWFALGYNSSGDEESTHWEDMVDALGDQMCRWHVLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1M0</accession>
    <name>A0A1D2M1M0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19829</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006976">
        <property type="protein sequence ID" value="ODM86853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1M0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="20445" checksum="306E20BD036DF274" modified="2016-11-30" version="1">MNLYFSGAMHEIISSANCTDLPADLKNFNGSIKTGGCIALFESSKCYSRGFVIRHEESRLSELESKYLHDKRQNYNVNSIRDCNELETGPGVNIDVYWSRYSTDYSGEEKTIGITPVAASDCPTVMDTMLMLTCMEIALKFMKTRFAQGSPLREYMEYMETFPTTGGPWSDVISQFTVIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1P0</accession>
    <name>A0A1D2M1P0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty-acid amide hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006923">
        <property type="protein sequence ID" value="ODM86874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1P0"/>
    <dbReference type="STRING" id="48709.A0A1D2M1P0"/>
    <dbReference type="OMA" id="CAWIETT"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052739">
        <property type="entry name" value="FAAH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372:SF4">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="1">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="507" mass="55879" checksum="47B44585C028FD87" modified="2016-11-30" version="1" fragment="single">NREYYSEISGAYENFKQWLALLQIRNREVTSEEVVCEFIGRIQEVNSYVNGLVDERFEIAVEEARKVDKLIQSGELDEVELKDKFPLLGVPFTIKDSFCVSGLRHTAGSYYRKDMIAVEDAEVVKSLKSVGAIPIGVTNVPELCMWWESHNTVYGRSRNPYDTRHITGGSSGGEAAVQGAAGSAAFGIGSDIAGSIRVPSLFCGIFGHKPTSGIISCRGQQPDVKGRLIELLTTGPMARHAKDLRLIFDVLIGESVHKMNKIPEKAQLRILFMEDDGGSPLASPVDPEMKDALRKAVQHLEQTYGVKAQVSPCNRLRRGLNLILVKANFSKLYHSLEIWVQAVSGAGGVPFCEELLLQKGKINPFWELVTFCFRLSPHTLPAIMLGIIEKMAYIGNQLPRHKLLIEMGYSLAKEIQDVLKDDAVLLYPSFPSPAPRHYVSLFRPADFSYCAVFNVLGVPVTQVPLGLGSKGLPLGVQVVGGMHSDHITISVAEELERAFGGWVQPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1S1</accession>
    <name>A0A1D2M1S1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FERM domain-containing protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19769</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006782">
        <property type="protein sequence ID" value="ODM86913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1S1"/>
    <dbReference type="STRING" id="48709.A0A1D2M1S1"/>
    <dbReference type="OMA" id="GCAFFYG"/>
    <dbReference type="OrthoDB" id="2142533at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051594">
        <property type="entry name" value="KRIT1/FRMD8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057096">
        <property type="entry name" value="KRIT1_FRMD8_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13283:SF10">
        <property type="entry name" value="FERM DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13283">
        <property type="entry name" value="KREV INTERACTION TRAPPED 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24522">
        <property type="entry name" value="KRIT1_FRMD8_FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="2">
        <location>
            <begin position="4"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00039547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="47255" checksum="BC64DBEE0C59730F" modified="2016-11-30" version="1">MRCCKIAVYLATGTAVILEPDSGSSCTAKELLQSIVESEELALPPYAGEVFSLWMASSFLEVQLKPNQQPLGVRKNWKRLLHNYSSATHLEAESDDPRICLRRSAFLTKQEEMRITDSKILELFYAEARHNILSGRYPCEADDYSMLGALQAGIEMGTYNAEIHTFEFFRQNQRQFLPEHVCEATWIPSFLSNRRKNAPAYLLLENFRRIPPTTPSRKLVRKYLELCWSLPYYGSAMFHGQVESPAKGLWSILDHPDNFVLVAINSHSLHVIDYYRNRILVGARFESLKVELGWPSNETNPNCLPCLFLQFSELESRQSKMLQIFSKQAPMMDALISRFHRARSRSHHGLESCDEVDGHGAMESADIDGDFFVSLKTVTQCGEENSCLSNKLSELALAAFDEEGICVSKAGSWAFAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1X5</accession>
    <name>A0A1D2M1X5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450 9e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_19712</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006574">
        <property type="protein sequence ID" value="ODM86970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1X5"/>
    <dbReference type="STRING" id="48709.A0A1D2M1X5"/>
    <dbReference type="OMA" id="ITMFEEN"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM86970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="43959" checksum="1A16198C9A2ECFBC" modified="2016-11-30" version="1">MWNDVKKTGKSFVGISDLISPTFYIADLELMKNIYIKDFDHFVNRRQFATPDSDLLLKKMMVSLEGERWKGIRSKLSPTFTTGKIRRMFGIFDKSSQLMCEYVKKRVGSAGGEFDICESYSKYTMDVIASCAFGVDSKSFDCEPGVLSEFEKMGERFQFKLNPAQFIKVLVLLIAPKVANKLGLEAFDTEPQKYFSRVIKDVMKRRRETGERRDDFLQLMMDAQKGLLKGEENSKETLEVMTGTDDGSGTAFHSQSEIKFDDDDIVANSVLFLIGGFDTTQSLLIFAAYNLALEQDVQEKLLKEVKASFDANGGKLTYEGVLEMNYLDMVINGMRFALTEVKAVVASLVYNFKLEPGTLTEIPVKFSNTATLKPANGMWLKMTPRIASGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Z1</accession>
    <name>A0A1D2M1Z1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006543">
        <property type="protein sequence ID" value="ODM86979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Z1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00696">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903387" evidence="1">
        <location>
            <begin position="19"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="147" mass="16339" checksum="F61F2F0641936FDB" modified="2016-11-30" version="1">MLFNLLFLGSLVFTVTISQNVTFPNAVTWVLGNSADHHNLTQRGKTSVGYDGREIETSDNQALQRGSTSWVPVQKNSKIPSSAVVAGIDPRSRLPEYVCRGYLLEDGRPWLIVGKYVEDLFACRVAYDGEVPIYSFEILIESGKLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3J6</accession>
    <name>A0A1D2M3J6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-erythrulose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19201</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005200">
        <property type="protein sequence ID" value="ODM87481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3J6"/>
    <dbReference type="STRING" id="48709.A0A1D2M3J6"/>
    <dbReference type="OMA" id="YFCATTV"/>
    <dbReference type="OrthoDB" id="6506490at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="26692" checksum="36ED9C83A76C005E" modified="2016-11-30" version="1">MSVQYNFTGVKFLVTGAGRGIGRAIVTELHNQGAIVYALSKNPDNLASLQKECPKIIPIYADLSNLEQTLNAVKPIEAEYCEIADFLEISLEQYEKQFSVNFKAAVFVSQNVVKKMIAAGIGGSIINISSMTSQRAIKYFGIYSCTKAALDMLTKSMALGIGVHKIRVNSLSPGTVKTDLVNYVVNQDPKEMEKQVQRFIERTPTQTLFMPMSDIVNATLFLASNQTSQITGQCLAVDGGYLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3R9</accession>
    <name>A0A1D2M3R9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein lin-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19057</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lin-9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004952">
        <property type="protein sequence ID" value="ODM87623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3R9"/>
    <dbReference type="STRING" id="48709.A0A1D2M3R9"/>
    <dbReference type="OrthoDB" id="2339771at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017053">
        <property type="term" value="C:transcription repressor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033471">
        <property type="entry name" value="DIRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010561">
        <property type="entry name" value="LIN-9/ALY1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045831">
        <property type="entry name" value="LIN9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21689">
        <property type="entry name" value="LIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21689:SF2">
        <property type="entry name" value="PROTEIN LIN-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06584">
        <property type="entry name" value="DIRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19438">
        <property type="entry name" value="LIN9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01135">
        <property type="entry name" value="DIRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DIRP" evidence="5">
        <location>
            <begin position="133"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="474" mass="53552" checksum="33A694FEC1813CAF" modified="2016-11-30" version="1">MNPPLKSKQQQVAKRSCPARFKQNVTPATPPKPVVADIEKKPEVIPTPPPPALALPAPPPQRASGAARFMLAGSTPTLTYNPLQLPILNAVQQQELIAENYNQRHGGLMDLSHRVRNFLKLPKSHKWVCYEWFYSTIDQVLFKAENDFQMCLRESFPALKTRKLTRIEWTTIRRIMGKPRRCSSAFLTEEQRASDEIPLQLVIGTKVTARLRIPQDGLFEGRIEGVDTSNSTYRISFQRSRVGVHSVRDFEVSSNEPVETVSTSSFVLKIPRRLVGEKLTLSKLLKKKRIKIAELRELNVEAEKMTSYGKPYNQAFKLEYARDMGELNKVIGKYMAGVQAYCVEIPSDSQHSTATAGATNTQASKMINSEQVLERCRQDASMMLFNFNDNKTAPGVKNPKILELIRNAATMMLGIRRIQSLIRVPSSETHSGIFKNTVKANVEGKNLRLYEDRVEMVMNRMIAGLCVKKDSDMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4F9</accession>
    <name>A0A1D2M4F9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004659">
        <property type="protein sequence ID" value="ODM87802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4F9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903454" evidence="2">
        <location>
            <begin position="23"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="43495" checksum="79F1D662E5595551" modified="2016-11-30" version="1">MVRILVLALCLVTFIQLKEVKCQLGVIYSPFVQSGDNPGTTKSYTLQNVKKMLNLLKNDNFHCISTYGVGATSETYQKNNTIYQSTSIVHTALAAAEINREKKQLALTVYQGLFPNPNRGFNSETEVSFEVAEAANKIYKGTVPALVFSSTVAFHELLYTHIIATLKNVSDRAHVSNLKFGVRLYDCVSMGVILNASQNSVNIQNLMELLDFIICTRIPPLSAYSEGPNIFKEQITKEILEVETTVKKMYNDTEVILETAWGGEMNTTNPYTTIEMKMFWEMMGLWANQQQKLVFMQEGFDNPWKVGIRELAFAAHFGIWKHSDEEQDFIRKGSKIETHNPPPVSAPVVPTGSNKTSKSKVEATIVVSSGCVANTHAMLITVALVWGFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4H5</accession>
    <name>A0A1D2M4H5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004473">
        <property type="protein sequence ID" value="ODM87885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4H5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="8644" checksum="AF8A6FC0A383540D" modified="2016-11-30" version="1">MEFVAGIASAIKTLEKRDLPSCDVWLLLQNVLDLTQDVLGRDTQKLIAYMEGRHPAISFWNDVQYFDPRKAKSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4J1</accession>
    <name>A0A1D2M4J1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18794</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004473">
        <property type="protein sequence ID" value="ODM87889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4J1"/>
    <dbReference type="OrthoDB" id="10595168at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="121" mass="13360" checksum="41D11E8219082798" modified="2016-11-30" version="1">MVASFTSAGVPLKIFRNPEVRKWIEANVKTGDTPPLRNYFKKTVDSRRKQGYRKTTEMCCNQSVIATVDESIDIKNRKLLNVLIGVAKPGSPARLVTSTFVKKCDGATVCQSVLDSLKLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4W0</accession>
    <name>A0A1D2M4W0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Uridine diphosphate glucose pyrophosphatase NUDT14</fullName>
            <ecNumber evidence="9">3.6.1.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Nucleoside diphosphate-linked moiety X motif 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_18665</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>UDP-sugar + H2O = UMP + alpha-D-aldose 1-phosphate.</text>
            <dbReference type="EC" id="3.6.1.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.45" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01004239">
        <property type="protein sequence ID" value="ODM88018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4W0"/>
    <dbReference type="STRING" id="48709.A0A1D2M4W0"/>
    <dbReference type="OMA" id="CLLYHKQ"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008768">
        <property type="term" value="F:UDP-sugar diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18887">
        <property type="entry name" value="NUDIX_UGPPase_Nudt14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000035">
        <property type="entry name" value="Uridine diphosphate glucose pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF15">
        <property type="entry name" value="URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="12">
        <location>
            <begin position="13"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00071467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00080475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="200" mass="22588" checksum="ADB51ABD13C66C15" modified="2016-11-30" version="1">MNNGKKRYWDMLKVHESVACVLYNTSRDVLIFVKQFRPGTQLKEDFIPYCAVFVYRALSTGSTTTSIEVEGQSVDWDKVSPNLGITLELCAGIVDETLNLNEIVKKEVLEECGYEIPSENFQRVTSYRTTGISGSKQTLFYAECTDQMKISEGGGLAEEGEFIDVVEMSIPQVRNLIQDEQVTRPATLLFGITWFLMNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5B5</accession>
    <name>A0A1D2M5B5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium channel protein para</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004006">
        <property type="protein sequence ID" value="ODM88177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5B5"/>
    <dbReference type="STRING" id="48709.A0A1D2M5B5"/>
    <dbReference type="OrthoDB" id="6766014at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0086010">
        <property type="term" value="P:membrane depolarization during action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019228">
        <property type="term" value="P:neuronal action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF288">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN PARA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ion transport" evidence="5">
        <location>
            <begin position="10"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="10361" checksum="27D367C8160A029F" modified="2016-11-30" version="1">MDKTHLFPGAEMPRWNFTDFGHSFMIIFRVLCGEWIESMWDCMLVTGGACVPFFLATVVIGNLVVLNLFLALLLSSFGASNLSFLLTPKRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M646</accession>
    <name>A0A1D2M646_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Farnesyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18223</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pheromone biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003578">
        <property type="protein sequence ID" value="ODM88460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M646"/>
    <dbReference type="STRING" id="48709.A0A1D2M646"/>
    <dbReference type="OrthoDB" id="10257492at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042811">
        <property type="term" value="P:pheromone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="216" mass="25177" checksum="A4C9407C3011D8B2" modified="2016-11-30" version="1">MNFTRMLKVGREFMNRQCNYSSYRTPMAVSNISSFRTKCHSLVGNSLAPPLPIFTPVRRLVQIGQATRERPQLLTEVERKDFMHVYQTIVNDLLEVPDMEDMKETNGWIERLNAGFLLLDDIMETGVKHDRGRQCWYKVDNLGLTAINDGLLLEIIIYQILEKHFKDKSYFHMAKKVIFDVTYQTVAGESLDLRTGKERMEKYCANTYNCLFVLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6K6</accession>
    <name>A0A1D2M6K6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine/tyrosine-interacting protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003395">
        <property type="protein sequence ID" value="ODM88609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6K6"/>
    <dbReference type="STRING" id="48709.A0A1D2M6K6"/>
    <dbReference type="OrthoDB" id="426001at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="18"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="9931" checksum="E82F03ECB60223C6" modified="2016-11-30" version="1">MKVTLFMASQIATLKGIIRHFKTVNAFIDECLSNGGKALVHGSTGNSRSAALVLAYIMSKFGVSLNEASSLVKSKRYSIRVNNGFMAQFEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7J1</accession>
    <name>A0A1D2M7J1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003051">
        <property type="protein sequence ID" value="ODM88935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7J1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="743" mass="85703" checksum="0557BC46E49E93FB" modified="2016-11-30" version="1">MSVETNESSNSRMEAVTETNSAVPNQGRPNPMMNCLVLQTLFEHSSITELKTYRQVCRLWWEESLAQWRREVWVKLGDDEYMARGLEDYPDEILGNSSADPLQFGKHPYRKYKLSKLKLGLVGDRQLEFWRKCGPKITHLKISKSCFHSVRQFEALLNQFVPNLEFLHLKKNMAPMDGLPEDESNLMDAPPQLKSKVFKELHLETQLFFINHPRLSVDWFWLLGQFPRIKSVSIANYDFVYSHRSYFPVVELDQILNAMITIKAEQGISWKLEKLDLLFMGGIQRPVFQNIHADLFRQLQLPLTTLCLHIGPATTKKSLKTLLESCAFTLRKLVVYRDDFTVNLEEDDELTMDFPYGDIGNSLGEDAAGSHFSGFQTFLQLSNMLAEQEDNREGHFRGNFRSVVEDTTSPPGECTLTRLMPNLKTLMIGLENDGFRVVCAGWKQLEVLIIQPYEVNQTGLTGSIPLIKHRLPNLSDLTGLRYFGMGFETSSSKMALTDESVLDAIFPLKNLQRITGYYNLEKMSEEVYDQLRSRFPNNWIFDKEAYDSEWLYELYANQSSDSDVEDEVELKESTFKRGVGINLEETIKELRRIRVAEREQMDLKHSTLLRENMTIQMKLDKLNERFERLKKKQIQAVAVGAEKLERSHQRRKPAAVNPVPVVPTGLVQLESNGREQDHQFESQATVEVYRSVVGWTDVGHPGTWKKGAQVKIPFISFEKERMDDKDYVKQRIEQIVGSGTDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7R5</accession>
    <name>A0A1D2M7R5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_17711</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003016">
        <property type="protein sequence ID" value="ODM88971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7R5"/>
    <dbReference type="STRING" id="48709.A0A1D2M7R5"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="17916" checksum="1BC7D8D9BEBCA014" modified="2016-11-30" version="1" fragment="single">CLLTEAVILEIFRITSIGPFGVVHTALTDIHLGSNYTISKGTLLIPNIYYIHHNKDVWGDPEIFRPERFLNSEGRLDSKRRIRHSHFRQCLGESLAKDVTFLYIAKLLQAFDILPDPSGVKPDFYTDIGFGQFPKAFNVVIKLEHNQYIFKVPQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8J3</accession>
    <name>A0A1D2M8J3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fizzy-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_17423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002767">
        <property type="protein sequence ID" value="ODM89259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8J3"/>
    <dbReference type="STRING" id="48709.A0A1D2M8J3"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="142"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="272"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="402"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="455" mass="51131" checksum="BAD61007E5980E91" modified="2016-11-30" version="1">MNTSTLSTTPQNVKSPKPRYGDRFMPARVGNSWHVTYPESPDKKVVKDEVDIDSDDDTAKPSSNTEVLDEQCSTYSCLLKNEVLGYDFDSSTVLDSPKKSSCRKLFILLIYKFERISSSSQKLLRTPVNKRRRIPKTPYKVLDAPDLADDFYLNLLDWSSQDVVGIGLGTHVYMWSAVNSEVTSLVDMQEFRDRPTSIKWNEKGDLLAIGSHEGCIRIYDTENKKCIFEEQLHDQRVPVLDWSGNNIFSGSKDRCVKVMDVRAPECGAVHSYSGHKQEVCGLKWSSFNSSLASGGNDNAVMLWSLHARKPIMTLKEHEAAIKGLSWSPHSRHVLASGGGTQDRCIKFWNTITGSCVASIDTNSQVCNIEWSPYSNEIVSTHGYAHNHVAIWKYPSLKLVAKLKGHTQRVLYMALAPDGETICTGASDETLRFWKVFEKSPCRVKKSSLDLFDGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9A8</accession>
    <name>A0A1D2M9A8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sec14 cytosolic factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002591">
        <property type="protein sequence ID" value="ODM89494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9A8"/>
    <dbReference type="OrthoDB" id="7837562at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="93"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="149" mass="17289" checksum="172EB8858D98375F" modified="2016-11-30" version="1" fragment="single">PQFKEVVSDLNQDEGVLLRFLKAKDYNVKMQKDVEEFCWLFLGTWAAKQLLESVDPEEIQLIEQGLQKTIECGSTGNVVIDMENLSYAQATHIATPWIFSFAFNFLKGVFAQKTMGKIRFISYKEEWQAEFLKRFPRESIVPELRPPCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9T5</accession>
    <name>A0A1D2M9T5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002402">
        <property type="protein sequence ID" value="ODM89746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9T5"/>
    <dbReference type="STRING" id="48709.A0A1D2M9T5"/>
    <dbReference type="OMA" id="VIRYINQ"/>
    <dbReference type="OrthoDB" id="7837562at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="105"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="282" mass="32339" checksum="EFA6A589D7B73929" modified="2016-11-30" version="1">MRSLQKKDFYGLLIPSVIAVLCFASLGNATNLEDELRITYDQKLAIDKLRGRVLPYLTESYMKEDLHMLRWLRATKFNVEEAQKRIIQNVKWRKQNKIATIHLEDFSDIADEFPYTFTVDKQGQPVFIGFAGEWDVRGAVLTGRAQRVIRYINQALEHGVKMVRDLQQEGKNVTRLNLIIDLDGFNIRQHGCVQCLFRILDFLLLYDNNYPGTADRVIFTNTPPTVAAAAEIVRANANSETMKAIKLYGHDKNVWRKALLEFIDSSMLPEKLGGTRKRSATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA57</accession>
    <name>A0A1D2MA57_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002346">
        <property type="protein sequence ID" value="ODM89812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA57"/>
    <dbReference type="STRING" id="48709.A0A1D2MA57"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052740">
        <property type="entry name" value="CE4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985:SF12">
        <property type="entry name" value="CHITIN DEACETYLASE-LIKE 5, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="71" mass="8201" checksum="0C951CAC3D1FA158" modified="2016-11-30" version="1">MDDVWLVTNWQALQWIGKPTSSNRDRPPRCNYPKVCNLWHKSGVRYMKTCQSCPQQYPCTGNTGLILTLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAE6</accession>
    <name>A0A1D2MAE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002320">
        <property type="protein sequence ID" value="ODM89854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAE6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19353" checksum="A09635748FF091C0" modified="2016-11-30" version="1">MIFQAVVLLKKAMGRSGTRRCGLNSPLSDKMEIIFDLLRDVYLLYEHEWVPLIAVDIISISLNKLQLTEEETKNATALSFRKNESVCIFLKNSQDLQELLSKLWTSMRKSDREDVLAKGAYSLVQLISVAARLKTMDIFVDIVSSIRRSVNSEVVKNPGVTTIVSHVMSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAN7</accession>
    <name>A0A1D2MAN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chorion peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16626</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002200">
        <property type="protein sequence ID" value="ODM90056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAN7"/>
    <dbReference type="STRING" id="48709.A0A1D2MAN7"/>
    <dbReference type="OMA" id="ENTATHM"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09823">
        <property type="entry name" value="peroxinectin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.640.10:FF:000003">
        <property type="entry name" value="chorion peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903715" evidence="8">
        <location>
            <begin position="22"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM90056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="685" mass="77044" checksum="BE8CB7E8E0FE4662" modified="2016-11-30" version="1">MKSAIILEIFSVGLLISQVSSTINKTLLEEKILVENVIQVSASKYDERMKLAFLNGAHSKRNQRELKKSTKYTQEIGRIGNIYIDAFKELTLKHNLERSSAIAHLRQALPKECEQPTIVCETFLKYRTFNGTCNNLNNPHWGSINMPNARLLPPSYANEIDEPRGGLDQTSVPAVRNLTLTIHQGGDDKYENTATHMVPQFGQFLDHDITLTPVDDLQCCGSTAPDCWTIAVAPSDPFYGNRSPPVECLDFVRSSPVCFPQEGVEHREQMNIHSSYIDGGMIYGRDDALASILREYKNGRLVENSQYPKFLPFKKQIVPGDESDEVIAGDVRASEMPGLTVMHTLFLREHNRIADIFATLTSWDDEWIFQETRRIIIAELQQITYNEFLPSILGPEAMTNYDLALPPVTEGNGYTTYNSSVDATIISSFATAAYRFGHTLVNGLIQLMMDGISVGSYRVKDNYGVSNQVLQDYTSTNGSSGYDMILNGLTRQRSQAFDTEIHKDMSNELFKNEHVNFIGTDLSARNVQRGRDHGTPSYNSFRRFCNLIPLTTWNNRPLDISEGAWEKLRSVYETPQDIDFYTGGLSQTPVQDGLSGPTFVCVQALQFQRLMKGDRYFFTHANTTGSFTPGQLAALRSRRLGDIICQNSALKETARNVFYRDETSSNPMISCEDASRNLDISLFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAQ5</accession>
    <name>A0A1D2MAQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High mobility group protein DSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16661</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMGB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002231">
        <property type="protein sequence ID" value="ODM90021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAQ5"/>
    <dbReference type="STRING" id="48709.A0A1D2MAQ5"/>
    <dbReference type="OMA" id="KICREQW"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21978">
        <property type="entry name" value="HMG-box_HMGB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF32">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="109"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="200"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="109"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="200"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="217"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="300" mass="33914" checksum="1F071BA4533F171A" modified="2016-11-30" version="1">MERLLHQQTKALGQYATPLRNVVSLNFTFNKGDTEKILFGQRDQVISFWFCFAAGCVHFLVNIRLVRSHSSAFTGNQRSSLVSVDLVVGVGTKMSGQTRGVAGGSSKKPKGPVSAYAYFVKICREQWKREGSEKLSFADHSKTCAELWKEMSASQKMPFVELQMKDKTRYQKEMRSYGLEPSPPKGQGQEDEKAKDPDAPKRGLSAFFWFSHDERAKVKGANPGGQGSRRMWGGMNDADKSKYQTMAAQDKARYQKEMEEYKRLAESRAAAATQLEEDDDDDDEEGEDEQDYEDDDEEMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDD5</accession>
    <name>A0A1D2MDD5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001697">
        <property type="protein sequence ID" value="ODM91026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDD5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="20846" checksum="AD308C596FBEDAAB" modified="2016-11-30" version="1">MDISASIPLQRYVKYLAILDAVLSFITLGPFILALSIFGATAFTEGLGDGRKILVIVAVLIVIDILAVRILMAAQLYNGAKTKDYRKCTMWFLFTIIILLLTVSVHFTSGSDMDQLSFRLFLVEIPCRAFELIVVMKFMRQITKEGIPNVAIVHLNPKERFTFNLTQNSNQSPYTSLCVQPQFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDL3</accession>
    <name>A0A1D2MDL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001692">
        <property type="protein sequence ID" value="ODM91043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDL3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903862" evidence="1">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="10090" checksum="1EB63FEB3009D0BD" modified="2016-11-30" version="1">MFSVQSQHTLLLLVLICLVITVSCNVYGNPYDPIGTYSYGKVSGFPAFSNRQTACPRPCFVDVSKGASQGLRSYESPIDTALACWIFSLDQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF18</accession>
    <name>A0A1D2MF18_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001486">
        <property type="protein sequence ID" value="ODM91600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF18"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903915" evidence="1">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="113" mass="12278" checksum="0AD586756EC93D0E" modified="2016-11-30" version="1">MRSIAILLVALVLVALVIVDINAEAGAEPSAGCPDKPTEPCWWNNWQFEGTQSVGASAIGLEDAIAAKPNGLLQFDITEHDNRKLISYVFVSKESTYKRFCAELCTSTDLCIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF30</accession>
    <name>A0A1D2MF30_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sideroflexin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_15172</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001527">
        <property type="protein sequence ID" value="ODM91512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF30"/>
    <dbReference type="STRING" id="48709.A0A1D2MF30"/>
    <dbReference type="OrthoDB" id="6608471at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140300">
        <property type="term" value="P:serine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF8">
        <property type="entry name" value="SIDEROFLEXIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="34571" checksum="04D737409E9CFD10" modified="2016-11-30" version="1">MTNSSKPHRLNLDDPRWDQNTYAGRFKHFFVTINPLHSLHSRETLEKARDIVTRYKKGENIKNLSEDEIWRSQAHLRLRLPPRLGSTDALDRADVFTGSNEHDSRRRMVSFFTRPNLPSYFGSEPFLNRQLGISYVLGTGGAMAISTGFQQLITRSGKQFPLLSRLVPFLGVAAATCVNIPIMRSQELVQGVPVVDAQGNRVGFSAIAAQHGISQVVFSRIINAIPPMVLPPLVMNILESRLRLRLLLRYPKLGIPIQMGLVGIINIFATPMCCAIFPQKSSISASKLEHEIQAKLPSPSTILYYNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFV1</accession>
    <name>A0A1D2MFV1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pogo transposable element with KRAB domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001393">
        <property type="protein sequence ID" value="ODM91868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFV1"/>
    <dbReference type="STRING" id="48709.A0A1D2MFV1"/>
    <dbReference type="OrthoDB" id="5422061at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="107"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="277" mass="32265" checksum="EFFAFBB2E0FBA221" modified="2016-11-30" version="1" fragment="single">KRIFDWISDAKCIPDSSTRKRAAVLRTRRRNLSKIRKSLVYYTGSMELNHFHHPNRVLKKLMLKWKQKYGNGLKVRIHERFPVQKKHGRIEIECSYGWYRRFKARMMSTNGPNTGYKEDDNLVLTWLLQVYDNNDLVSYKDLQCYAQNAFQEIKPEFKASAGWAMRFLKRYHAVINWDGIYLDPLPPALECQVDNFRVQMKASLDQFSTNSVGCMDEIPLNFTNPTLGTKATEHDPQPVSRLRKYSIKNCDATVILGFLADGTLLPPMVIVKVRSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG16</accession>
    <name>A0A1D2MG16_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001377">
        <property type="protein sequence ID" value="ODM91938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG16"/>
    <dbReference type="OrthoDB" id="413313at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903972" evidence="1">
        <location>
            <begin position="24"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="8613" checksum="11CFA874B0FE02BF" modified="2016-11-30" version="1">MGKVWNHRGLCWDLNLSWQVLLGLHTKVCDHGWEKTNATFNFVWSTALAHEGLNDGRMGDEHLLTTLKCSMMKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGX0</accession>
    <name>A0A1D2MGX0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vitelline membrane outer layer protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001296">
        <property type="protein sequence ID" value="ODM92215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGX0"/>
    <dbReference type="STRING" id="48709.A0A1D2MGX0"/>
    <dbReference type="OrthoDB" id="6329319at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00220">
        <property type="entry name" value="VMO-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841:SF0">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03762">
        <property type="entry name" value="VOMI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
        <property type="entry name" value="Vitelline membrane outer protein-I (VMO-I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904016" evidence="1">
        <location>
            <begin position="28"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="47609" checksum="E7338B218991F762" modified="2016-11-30" version="1">MVKILFKMNMLNLAILTFCSVFSAVSANINITSPPITNWGDWGRFQRCPFGRYAQGFQLKTEANLGLFQDDTALNSIKLFCGDPYRPDTAVLTSTEGEFGKWGNIYSCYPGFLNGFQLRVEEYQGSGDDTATNNVRFYCTNLPTPNDYIEGDGLSYGSWGQTQHCYSNQVISGIQTQVEPNRGDDDDTSLNNVLMECSDYVKANVNEEERKIEEQAASLIAINPKFAHILTMFTKSCMLKYTLLTVAATANINITSPQVTNWGTWGRFQRCPFGRYAQAFQLKTEPNRLAGDDTALNAIRLFCGNPDRPDTAVIMSTEGQFGNWGKVFSCYPGFLNGFSLRAEDPQGSGDDTAANNIRLFCSNTPSYVEGDGLSFGNWSLDQLCLRDQAISGIQTQVEFSQGDEDDTALNNVLMECTNFPQANSKTLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGY7</accession>
    <name>A0A1D2MGY7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001282">
        <property type="protein sequence ID" value="ODM92268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGY7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="161" mass="17498" checksum="F1BC4C093AC94DE5" modified="2016-11-30" version="1">MTFMYTLIVYSYIIDRSFFRLTLFDYRQTFKMDSKSSATGSNLQGSEKTKLPSPLLFIVVGLIIIIGIASVHLFLSGLVCFVIGFDFKTVLYVSTAAIVSGTVITMALAVLMSLYCVLSFFARFNAPSSGSIAAELSNLKDLSPDVGEDKATGDSLDKKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH52</accession>
    <name>A0A1D2MH52_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001282">
        <property type="protein sequence ID" value="ODM92263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH52"/>
    <dbReference type="STRING" id="48709.A0A1D2MH52"/>
    <dbReference type="OMA" id="NDMNESH"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-4" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="22039" checksum="1CCB4DFA9801B5D6" modified="2016-11-30" version="1" fragment="single">MEPPSRSSLWHFEEYEEFNPPINYDDTQLFCGSKEVQYNENGGRCGECGDAWNQTKPRDNENGGLYGNGLIVRNYTRGQNISVAVELTAPHLGHFEFKVCPLRSSSDVEEQSCFDRYPLQILQESGTEFDNEFPIDNGLGWVNVTATLPSDVTCEHCSLLWYYKTGNSWGDCGNGTEAIGCGPQEEFRGCADVTILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHV4</accession>
    <name>A0A1D2MHV4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative leucine aminopeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14173</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001212">
        <property type="protein sequence ID" value="ODM92511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHV4"/>
    <dbReference type="STRING" id="48709.A0A1D2MHV4"/>
    <dbReference type="OMA" id="YEESTCG"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904065" evidence="9">
        <location>
            <begin position="20"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="155"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM92511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="40411" checksum="4219A04C103E558D" modified="2016-11-30" version="1">MKFFQLLLVASVGVILVSSRAVEQEGKRLIKTSEEDPGQWMDENEIFDLIKAKKTFIDITDSDFPEIKPEDVNIKAIPTTLRFQEIVRDVLTNLNSQRIEDFVREFSSYHNRYYAAQTGRDSQLWLLSQVESSIQGYAGSASVVEVDHGYIQKSIVARLEGADPTLKSEVIVLGAHLDSINIRGSSLQAPGADDNGSGSVTILETLREIVESQVVLNRTVEFQWYAAEEIGLRGSQAIAQAYRRDNVNIIGMLNLDVVGYYVNGVDDIGIYTDNGNAQMAQFLRILTDEYLEFGRRDLTCGYGCSDHASFTNAGFPAVMAGEAVDHPGMHTVTDVLENMSIRQVNEFVKLSVGLTIEMGEPNRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI29</accession>
    <name>A0A1D2MI29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase sina</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14018</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001178">
        <property type="protein sequence ID" value="ODM92658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI29"/>
    <dbReference type="STRING" id="48709.A0A1D2MI29"/>
    <dbReference type="OrthoDB" id="441278at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052088">
        <property type="entry name" value="E3_ubiquitin-ligase_SINA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049548">
        <property type="entry name" value="Sina-like_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10315">
        <property type="entry name" value="E3 UBIQUITIN PROTEIN LIGASE SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10315:SF117">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21362">
        <property type="entry name" value="Sina_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="302"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="379" mass="43393" checksum="2BD7AD9DECA0F9CA" modified="2016-11-30" version="1">MDDEHQKCPICMDIPEKEIYQCVGGHIICHICIANLSTCPQCREPYGAKKIRNRILEQILDKQTFDCLHVEGGCVEKLKRQELLKHAVICPQKPIFLCKILGYHNCNFQVHPSDRKRIVQHFKKRHSAQIKSTNKFCLWHADFGVATEALKDREWNPILLTLNNQWCKDSVFMIAGFFDSTRKSVSWRCIQLCGNDEPNYEVEFTMVQEQEKIPLFKWTVPVSNLNSPAQKLGVKYVEIPLSDIHSSLGKISKIPIQVVVQPSNLFEKPGIIKKPVEVWTYSSEAKSADKPQGVENNQQEVHATIECLLCEQNPILGKRYKCLQCYEFNLCENCKSLGVHDYHIFATISTPRQGEVLESVFPQICQQLELASITAGVYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIL0</accession>
    <name>A0A1D2MIL0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14043</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001180">
        <property type="protein sequence ID" value="ODM92644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIL0"/>
    <dbReference type="STRING" id="48709.A0A1D2MIL0"/>
    <dbReference type="OMA" id="KMFGDNP"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM92644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="501" mass="55492" checksum="DA58B99FA1D98420" modified="2016-11-30" version="1">MSSVAKNAYTELVSSVRKTFNTGKTRPISFRVQQLKNMEMMIRENSNEILDALSKDLRKPKLEATLYELEIILNELKGLIKNCKKYAEADKLPVNLLAILDTAYIRKEPYGVVLVLGAWNYPVLLSLQPAMGAICAGNCVVIKPSELASHSAKLMAELIPKYMDADAYRVVLAEVEGTKDLLANKWDYIFCTGGTNVGKAVMQAAAPNLTPVTLELGGKSPCYVDESADFDLAAKRILWGKFANLGQTCIAPDYVLCSKNAEKAFLKVANIVLKEWYGDDLQGNSDIPRIVNPRHCKRLKALLETTRGKIVFGGTTDEKDLWIEPTIVVDVDGDDPLMQDEIFGPILPIITVNSIQEAIDFINGRPRPLALYSFAKNEKMNDRLIENTTSGGVCVNDTMWHMAWHGLPFGGIGDSGMGNYHGKFSFDAFSHHRSVLNRSFSVLSEKLGEARYPPYTVGKLRFFQTILKSFEFFNCTGGKYITHLLAAMIGAAIFALITYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJD6</accession>
    <name>A0A1D2MJD6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Ubiquitin-fold modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_13641</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ubiquitin-like modifier.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the UFM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001092">
        <property type="protein sequence ID" value="ODM93042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJD6"/>
    <dbReference type="STRING" id="48709.A0A1D2MJD6"/>
    <dbReference type="OMA" id="MEHAVGK"/>
    <dbReference type="OrthoDB" id="284357at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990592">
        <property type="term" value="P:protein K69-linked ufmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01766">
        <property type="entry name" value="Ubl_UFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000044">
        <property type="entry name" value="Ubiquitin-fold modifier 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005375">
        <property type="entry name" value="UFM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15825">
        <property type="entry name" value="UBIQUITIN-FOLD MODIFIER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15825:SF0">
        <property type="entry name" value="UBIQUITIN-FOLD MODIFIER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03671">
        <property type="entry name" value="Ufm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038027">
        <property type="entry name" value="Ubiquitin-like_Ufm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM93042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="89" mass="9581" checksum="DBACC2081C3D306A" modified="2016-11-30" version="1">MASKVTFKIVLTSDPKLPFKVLSVPENTPFTAVLKFAAEEFKVPPATSAIITDDGIGINPQQTAGNVFLKHGSELRLIPRDRVGFAVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJS3</accession>
    <name>A0A1D2MJS3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein-likeNoc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13503</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Elbow/Noc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001051">
        <property type="protein sequence ID" value="ODM93181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJS3"/>
    <dbReference type="OMA" id="LMYPSPH"/>
    <dbReference type="OrthoDB" id="10054079at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051520">
        <property type="entry name" value="Elbow/Noc_ZnFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12522:SF4">
        <property type="entry name" value="ZINC FINGER PROTEIN ELBOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12522">
        <property type="entry name" value="ZINC-FINGER PROTEIN NOLZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="497"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="50"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="102"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="653" mass="66005" checksum="0EC62DE85A3EF2D5" modified="2016-11-30" version="1">MVVLELEGHNMLGSGPNQYLQPDYLSPLASPLDSKVSPLALLAQTCSQIGADGPSSKSIFETSKRKLSTCSESSIKSESSDSKDSVNNNSKEYSSGGGGGSNSHSNNNSGGNGSGSSRPKSSSSCSSLSGVNNTTSSSSSSNNKSSHNGGKSSPVLSPNGHSPVFKPYEITKSSKETSSEKHSERSSSKSKHHHQRESLSSLSRGSANCSPKAKTPNLRSSPDNSKNESHSSSEPKKSSNSSGNGSDRSNTVEQSKPSPDNGAGSSPIIRSGLEVLQQGQFGSSSAAAEYNRKLSALHSLSALGGYPPGFDPMNPAFRPPFMGPPHPHAAHMGYALPGSSPYVSYSRVKTASGAETIVPVCKDPYCTGCQYGGGGAPHGASSGGGGQSTSNMNGLMAAAAAAAAAAGFPGFGGASSPAAQASLICPAGCVQCDHPKFPLSSFPHLFGLGGGGAGGSPHPSLASLGGYPSSLLSQHSAAVAAHSAAAAQQQQNAQRPYVCNWIVGDNYCGKRFPSSEELLQHLRTHTNSSGSASSSSGADSAALAAMVQQQHQIALSHAAAGVSSSNALYSNALLNQSAMAAAAAAMHRTYPTPPLSPLSAARYHPYAKASGLSSNSASPGSVAAAAALSSYYPYSAAAAAALYGQRLGPSVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML63</accession>
    <name>A0A1D2ML63_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Neuralized-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000913">
        <property type="protein sequence ID" value="ODM93789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML63"/>
    <dbReference type="STRING" id="48709.A0A1D2ML63"/>
    <dbReference type="OMA" id="THANMGE"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037962">
        <property type="entry name" value="Neuralized"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006573">
        <property type="entry name" value="NHR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12429">
        <property type="entry name" value="NEURALIZED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12429:SF8">
        <property type="entry name" value="NEURALIZED-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07177">
        <property type="entry name" value="Neuralized"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00588">
        <property type="entry name" value="NEUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51065">
        <property type="entry name" value="NHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NHR" evidence="2">
        <location>
            <begin position="29"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="293" mass="32959" checksum="2DCBDA340552DCCA" modified="2016-11-30" version="1">MLLDSSYPSKEIFLHAYQKRPFHELITRTNTFHRHHGSNIVLCQERVTATRSTSFANALTFSEKPLASGELFLIEIEENETGWSGNMRIGLTQMNPSKEFPLPMYALPDLVSMGPSWLYAITKTHNNVYSAARRETSRAGELLRRRGRNSQGDDAEADPVLQGESDDPDQNNEENNGVPNDALVQEALFSYRRSPIVLQTGEGSLVRTPRGFIQLKALLPSITKSREYEGMNLLATDIGSRIGVMYVPTSETKADMHFIINGEDQGPCARDIPYQVSLCTQLWTFMALPKKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLI5</accession>
    <name>A0A1D2MLI5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000918">
        <property type="protein sequence ID" value="ODM93772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLI5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="252" mass="28697" checksum="2F4A634E4DC26610" modified="2016-11-30" version="1">MMDVLVALLRNWRLLRAEEEAGPSFMDDLPYNPFLNPLIITKIFDNSSQKDLLNYRLVCKTWNGFATALLQSTSYATVRLESDLKRLLRLTKHSSSSFPITRFYIKLHTLDNTSHLLKTLSMPTIVSLKVVIPSKLFPQSLRAIQQHMSSLRHLVICRLPELSFEAIVPVSADTERATHYGKMPKLLSLTLRNGNPNRNFLATYDLVVADFIRSAKSLKSLDFCHWNCLARVFRECSLDSLKSLRVVGGKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLS4</accession>
    <name>A0A1D2MLS4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tyrosine recombinase XerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000898">
        <property type="protein sequence ID" value="ODM93878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLS4"/>
    <dbReference type="STRING" id="48709.A0A1D2MLS4"/>
    <dbReference type="OMA" id="IHIDEIC"/>
    <dbReference type="OrthoDB" id="7699712at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00397">
        <property type="entry name" value="DNA_BRE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="124"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="330" mass="37128" checksum="E7AB35FBA0CBCB60" modified="2016-11-30" version="1">MAVNYAFGSCSGELETLNLPKTTLELLQASCAPGTWKQDHAVTKQWFAFCTTNHVIKPHKPSIAQVLQFLSELFDKGSSYISINTARSALSIILHSIDGEKVGCHPLVVRLLKGVSRRRPPQSKYVTTWDPAKVLNLFDSWEESDHLSLEKLSLKLVGLLALASGQRAQTLVSIKVDNIVINNDVQIIISDRLKTTKPGRITELLFSQYPTKKLCVKNTLEEYLKRTKIHRTSDRKQLLLSFRNPHNQITSQTLAKWLKRVLEMASINTNEFSAHSFRHASTSKALRSGVPIDSIFKAAGWSSNSKMFARFYNRPVVDNKNSFMSGVLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMJ1</accession>
    <name>A0A1D2MMJ1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N6-L-threonylcarbamoyladenine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_12499</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000847">
        <property type="protein sequence ID" value="ODM94183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMJ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MMJ1"/>
    <dbReference type="OMA" id="HHRSWVV"/>
    <dbReference type="OrthoDB" id="10254073at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:tRNA N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd24132">
        <property type="entry name" value="ASKHA_NBD_OSGEP_like_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000038">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000295">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03722">
        <property type="entry name" value="arch_KAE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="11">
        <location>
            <begin position="27"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="130"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM94183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="334" mass="36891" checksum="551293215D127BCC" modified="2016-11-30" version="1">MVIVMGMEGSANKVGVGIIRDGEVLSNPRKTYITPPGEGFQPAETARHHQGVIVDLVDKAIKEAKIKPEELDAICYTKGPGMGAPLVCVAIVARTLAQLWNKPIIGVNHCIGHIEMGRAITGAQNPTVLYVSGGNTQIIAYANKRYRIFGETIDIAVGNCLDRFARILKLSNDPSPGYNIEQMAKKGKKLLQLPYVVKGMDVSFSGLLSFIEERYNSLKKQYTPEDLCFSLQETVFAMLVETTERAMAHTGSQEVLVVGGVGCNERLQKMLEQMCLERNAKCFATDERFCIDNGAMIAQAGLEMFKAGVITPWDETFCTQRYRTDEVEAVWRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMX3</accession>
    <name>A0A1D2MMX3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NOT2/NOT3/NOT5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12273</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000809">
        <property type="protein sequence ID" value="ODM94410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMX3"/>
    <dbReference type="STRING" id="48709.A0A1D2MMX3"/>
    <dbReference type="OMA" id="QQDHAKI"/>
    <dbReference type="OrthoDB" id="25391at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000036">
        <property type="term" value="P:regulation of stem cell population maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="183"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="33204" checksum="4C79A167F65E9B50" modified="2016-11-30" version="1">MESYTSLKHYFEQSSDFKLANGNGGMSLEQRSAQNQLPSLSPLPATSSPNKSELEFNFSMNPFASVHCQPKHTTFSENGDVHNLPKSMLQDQYGVAGLMVGRKLAAKGMAPYANGVHIADDLLDKPDLYEPLHERFGGPFHNTQLETDRQEQVLNPDYLVSSRMISENRVSGIDDLRRLWALRLDNCKEDVLFFLFYSFPKDALQLVAANHLYVKGWRYHTEYKIWMQRTNSYGFVSDGSREKGVYIYFDYRIWKLMRTECVVDLSKLEGPPNKPPEPGQQPQCFSRENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN98</accession>
    <name>A0A1D2MN98_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myofilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000821">
        <property type="protein sequence ID" value="ODM94331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN98"/>
    <dbReference type="STRING" id="48709.A0A1D2MN98"/>
    <dbReference type="OMA" id="KNRYLWT"/>
    <dbReference type="OrthoDB" id="6328862at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031828">
        <property type="entry name" value="Myofilin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15929">
        <property type="entry name" value="Myofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27924" checksum="688A0C3433D0A2C0" modified="2016-11-30" version="1">MSFKNHFDMLSLHEPVTHKARFWQSYVRALKGTEDIRADEHQARLRLRPRALSEFPEFFGKSLLDDRLVSDPNTRIHAPGYRYMPISRETYGYSPRPIYPRPILTTRGSSVPPELEIPSWRESSPVPVYPRSHYSPKPWDRESTPAPSTPSYYYGGGVPMHGSRGGYNYRPYSDLYNPSPNLPISMITRDPWWYDAYGLRPYSIYPRYPRYPSALRTSYLSPVKNRYLWTRHPLRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP07</accession>
    <name>A0A1D2MP07_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000785">
        <property type="protein sequence ID" value="ODM94584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP07"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="582" mass="65936" checksum="6EB016F97E33D345" modified="2016-11-30" version="1" fragment="single">YSSLKPILYNESVKIRFFALFICCPSVENQVNERPSQFLAMKSYTLFAATVALIATVAFAQGSAAKNLKRDFSELTSFERLLFQFTRPDTYNNLSGRSGSKSPGINSEYSPIDFLNFDLPTLALQLSKSGSTFLPTVHFEYGFYYCYMGICIGFLQQYDYNKPEIRNANLTKANTHINDTNLEFDFQIPDLQIVMEDFFLHDEDLITGDIQMWRGLSLLISNYTLQLSANLEYVADVGIQLSNVSMNFAVGDFKLRRENGTHILPDGTTEEYGSVEREIASYMNEDWITYGEEVTASAQAWLNCFLSNGRNGDAQCEELLNDNLQPVNFMQLLQTIGLGIARNQEKLSIMNPQKIQDVLTVPHFLPSFPFPTMQSVLLELPTLLLQLGKVFFSTEAYPVSGFPMSYDYIRQNCSVGGCRDVHEQMFLPEFTVGGIIYDKLQVEITPDSFSYSIKVPEVYLDAPTLQSESTDVESGFREFYLGMKLSVVDAAFAISGDYSFEKGVGLQVSDLGLTLRLGELQMSFPQYFTTQNGEQSEIVEYNVDIAPQIMEIWNSVDENGVTFERQYEEYIQNVINAYLLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP31</accession>
    <name>A0A1D2MP31_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative Ras GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000749">
        <property type="protein sequence ID" value="ODM94797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP31"/>
    <dbReference type="OrthoDB" id="6435470at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="9154" checksum="8CE4F3247A0159DC" modified="2016-11-30" version="1">MRRDGKVDNNNMLNINLWFLLSMSDRDIPMGHSPRGNPPDVEWEPYFCVLNQLDQTFTSYRSEEMSLFMSNKYQMSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPG3</accession>
    <name>A0A1D2MPG3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear fragile X mental retardation-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000756">
        <property type="protein sequence ID" value="ODM94761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPG3"/>
    <dbReference type="STRING" id="48709.A0A1D2MPG3"/>
    <dbReference type="OrthoDB" id="273070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039136">
        <property type="entry name" value="NUFIP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="33830" checksum="CCFA6149FAB14732" modified="2016-11-30" version="1">MDQNQNQMHPNFAVPSPPPRFWGSNQGFRQLQGHRGRSYQHHVPNAAYPHVPFQSPNEQRPQLNRSQGQNHHRGGGQSINKRYRGGGGQNSSGVRGGNSKNWRGRHQPHNLQPISRKDVNSKSNFYCCACDRGFPTGEELDSHKSEHITCGLDGCKFEAHALIVTKHIQMQHTNGLYERIKDLNTPEDILRWKEERRSKYPTLENLQNKKGARKERDERREVFQQGGAHQEKIFRYKIPPDYDKRRENEYLWMERTLRQMEYKQGDAWRTRMFAPDLKSAPQAGPLRVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQX6</accession>
    <name>A0A1D2MQX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000697">
        <property type="protein sequence ID" value="ODM95204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQX6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="20909" checksum="247D6B69C27A0721" modified="2016-11-30" version="1">MHFLVPLPIIMFFIVSSLLIFCIAISVIFYNACVEVLIPLLEDSRAYRQFIARISQAVYFLFLEIRNDALFYLGIVCESDGDDEEVGFDDDYHQCETFPDCDIVKSSPKEEVLPDPNNNRNAPGRAARRRRVLPLGLNDPPVNRRPGPAIRLPANPQNPRAAVPPVRIRVVELGEDDLRELVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRR3</accession>
    <name>A0A1D2MRR3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000645">
        <property type="protein sequence ID" value="ODM95612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MRR3"/>
    <dbReference type="OMA" id="HSTLTYY"/>
    <dbReference type="OrthoDB" id="6022711at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06759">
        <property type="entry name" value="PDZ3_PDZD2-PDZ1_hPro-IL-16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11324">
        <property type="entry name" value="IL16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11324:SF16">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="1029"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="1358"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="823"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="947"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1155"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="764"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="839"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="956"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1470" mass="155318" checksum="71975A2841E68478" modified="2016-11-30" version="1">MSSFATWSKKMGKTWNQLKNAGEIRLSASGELETPTTPTNSQPLSELTSNTNVNPSSAPSSSSSASKEKEKKSSSKNSGNSSSGGGTIHRQWRLVLRNNKDHHHQYYPHHHINQPYSHHQNVQPTSLVQTCSSPSSKAPQPQKLSASKSKQRKSLDVYMKPCSASEENLGSISGNGSDNRKSRGGKPSSGSSNLANDEFYVNLKDYTARKCATLKPPSSKERKSKVDRVESIKGMLMGSRNSTKSPSRPSSSDKPPKTTAPEKTSSSKHENTGGGTLRLVSSTLRRPHLNSRHSTQVPTSSASTSSHLNSSPLFRSCSTSTLPSYIAGEDPASDLDLMLHSNSTSNSTSTSGHWNNSSCSSSPPFQVMSQHLSHSNGKLSSLQHHNNNNFSSKSKMLLLGASCYGVCNNNGSGSETSSAVCSPTKKSASVDNIAGMLLSSSTNMTTITTAAAALSQSSPSTGNDVNSSNSTKKFGFPHGFVRSKLTVLPEEAIHHHQKLLVSSVSSDSVHLALAECTGGGSSSTSGVSSDCSSNGSGGGGSVKPPKPSSLNLNSSEPKCQSLSLSHSFSRIISRSGSTDDQLSGSKSEASTPTSGKPSSLIFFRGRRHSSSKRSRSNSPASASGSVVNLNTPPQVVSSSAGGPLSFLRGSTPRRSQNRDVKSASNSCEMLLDEVVVKSGGIMGSKRRARSNNGDGKKLFPRSSSVDYDRNEEDDELVQISGSTSTILLDGCAGGGGDNCSSGGSSGTGDCHKEVSPASSTCQLSSSSHPHPPHVTVSTAGSLLLSNNSSSSSSGGGGAHPSVSGGPLPPPLVNGMMVAYISSNESGYDSDSNKNVEENQSQNQIQTSSSSSSSQPKSVEVLLDSRKAPSILISKDSPRNSWGFGGIAPVVPSPSKNAVVRRKSDLANAVITRQGTAQPLSSPGYCSLASCANPQECDKNPALPCSGSGRLSQQDNHHHHYHLSSHHHRQQVPAKVQWMESREIFRLYASGAGGSGCGSPSPYLMNTPTPTPPPPPPPPQGQVAKKKFQLLQISKEPNENLGISLGGTENNSATKSNGVPEHFVTSLRPESPAQRDGRIEPGDEIVNINGKRIRGLSTSEAELVLSSTSINCPQLELLIARENRKPLTLDTIENNDVFLPSLTCLDSIELNSLPPSQGLSGPTSLGIRGGYGNSSTGNYPHETIVEQSDESLENQAEPEMGTPTPSTILEGDVEDDNELRKVTRRKKLPSFLMMSGGVDTPSPSNCMHPSGYFASSSVEPMSMDGSGPTPVTVQKRNRRHSTLTYYNADADAINAGFAPYPLPHHAAAESHHHQSSLALGGGGYGDPLPNYYLTASTICTLPRKSKQDKNGGPPYKVYTIIFEKGNGKKGLGFSIVGGRDSPKGSMGIFVKTIFPNGQAAEKNTLFEGDEILQVNDVLMPGLSHSEAILVFKRIKTGEVLIRVKRRLGLVKPRSPTPSKSKSCDELDSIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSD3</accession>
    <name>A0A1D2MSD3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin-H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_10732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000603">
        <property type="protein sequence ID" value="ODM95943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSD3"/>
    <dbReference type="STRING" id="48709.A0A1D2MSD3"/>
    <dbReference type="OMA" id="EPQIMLK"/>
    <dbReference type="OrthoDB" id="340962at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000029">
        <property type="entry name" value="Cyclin h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027081">
        <property type="entry name" value="CyclinH/Ccl1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00569">
        <property type="entry name" value="ccl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 7" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="8">
        <location>
            <begin position="59"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM95943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="30313" checksum="B29CCA5CBA8E4F7C" modified="2016-11-30" version="1">MFATSTQKNHWIFSDEETLIRIREATNKAYVDQFRPPEDVGDFFLSATEERTLLHFYEYQLKEFCVKFQPTMNKAVIGTAFSYFKRFFLYNSVMDYHPKEILVTCVYLACKIEEFNVTIAQFVANVKGDREKAQEIILNNELLLMSAVKFHLTVHNPYRPVEGFLIDLKTRHPVLEAENLRPFIDEFLDKVLMTDVPLIYAPSQIALASVLEAARKCREHLDVYVTSILITDEEMLQSVVDAIRTIRLMVRVKNYDPPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSK1</accession>
    <name>A0A1D2MSK1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase TRAIP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000586">
        <property type="protein sequence ID" value="ODM96067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSK1"/>
    <dbReference type="STRING" id="48709.A0A1D2MSK1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090734">
        <property type="term" value="C:site of DNA damage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052639">
        <property type="entry name" value="TRAIP_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46569:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RFWD3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46569">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRAIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="100"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="174"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="273" mass="31432" checksum="64BE1FF2D47327A3" modified="2016-11-30" version="1">MATLCSICQDYLTERPQALRAEEDVIMCALTCGHLFHRVCVSQWFNRALRWSWWANLIFYFIRDGICPCCKKNVSLNNALRVYPTGDEEGDRMVRQDRDLKKVTEENLRLHAQQEELRQQLQRARSTLEEEVVAHDILKMEYGQAASRCETMQNELQDGKDMKLAIENSYKSALEKSEGEKTDALQRLTEMETQHDDTLGQVQQLKKMVEKLQLQDARRRQENQYLQASLFSKDAGMEKLPGKQGASKPTAGRLLMNGRGLSEIDAEPELVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSW8</accession>
    <name>A0A1D2MSW8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_10461</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000561">
        <property type="protein sequence ID" value="ODM96219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSW8"/>
    <dbReference type="STRING" id="48709.A0A1D2MSW8"/>
    <dbReference type="OMA" id="LNQISHP"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043068">
        <property type="term" value="P:positive regulation of programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21889">
        <property type="entry name" value="SARAH_Hpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06612">
        <property type="entry name" value="STKc_MST1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000040">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000075">
        <property type="entry name" value="Serine/threonine-protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.170.10:FF:000002">
        <property type="entry name" value="serine/threonine-protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.170.10">
        <property type="entry name" value="p53-like tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024205">
        <property type="entry name" value="Mst1_2_SARAH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036674">
        <property type="entry name" value="p53_tetramer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011524">
        <property type="entry name" value="SARAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11629">
        <property type="entry name" value="Mst1_SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50951">
        <property type="entry name" value="SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="30"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="SARAH" evidence="16">
        <location>
            <begin position="599"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="428"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="458"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM96219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="653" mass="72706" checksum="699EF732CDF30E8F" modified="2016-11-30" version="1">MEQQASSPTNKSELKKLSEESLTRQPEEVFDIICKLGEGSYGSVYKALHKESGQVLAIKQVPVDTDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEFCGAGSVSDIMRLRKKTLTEDEIATVLTDTLKGLEYLHERKKIHRDIKAGNILLNSEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYDCVADIWSLGITALEMAEGRPPYGDIHPMRVIFMIPSKPPPTFRNIEQWAPEFIDFVSKCLIKNPDSRSTAAELLNHPFITYSRPPSILLGMINEARQIRENLQNGIYPTKIPAPNSEGNNFQDSNDKTMKPADDRTLIPGMLSDNGDMDYSDGTMIAHSASGTLVNTGGNLGTLESSLGTMVINSDGEDDDDSTMKRHDTAEIDPAKKSYRPLFLDHFDKKDAAAAAANGNNGSSNSDEGMGGSPSTNDGNGDFTSPHQQQSSSYYHPNQNPNAMVSSYTNIPRNSTLPPVHLPPAFNQAHVDLYNDTKQMTAEEQREFAERLQRQLSQISGMCGASSAILGYRGGMMYGNGHSPSTAAADEAYAPAVELRRPQINLEAALIANPKYSKTFIDNMDFEFLKFLSIDELERKMENIDSEMEKEIDELRKRYQTKRQPILDAIDCKRKRQQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT08</accession>
    <name>A0A1D2MT08_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL39</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L39</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000568">
        <property type="protein sequence ID" value="ODM96173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT08"/>
    <dbReference type="STRING" id="48709.A0A1D2MT08"/>
    <dbReference type="OMA" id="RRTKMNI"/>
    <dbReference type="OrthoDB" id="6332053at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1620.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein-like L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_eL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_eL39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_eL39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_eL39_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970">
        <property type="entry name" value="RIBOSOMAL PROTEIN L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="51" mass="6383" checksum="41A0197F0A676054" modified="2016-11-30" version="1">MSAHKTLRIKRKLAKKMNQNRPIPQWIRMRTGNTIRYNAKRRHWRRTKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTP3</accession>
    <name>A0A1D2MTP3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BTB/POZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000545">
        <property type="protein sequence ID" value="ODM96376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTP3"/>
    <dbReference type="STRING" id="48709.A0A1D2MTP3"/>
    <dbReference type="OMA" id="VSCDRIH"/>
    <dbReference type="OrthoDB" id="624345at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774:SF3">
        <property type="entry name" value="BTB (POZ) DOMAIN-CONTAINING 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="42582" checksum="20D9A467B547AE04" modified="2016-11-30" version="1">MDPNMDRRPWDWNAMVTWKGRARTLMESEYLSDATIVLSSVGNDGNEKCYNVHRIFMESASPSFQRLFREADDTSMGGRCTILISDTPSHIMDMIIRYVYLDEVEIQDLDQSLELLGSAICYKVFGLIRLLCPRIINQIKSDNALKIYKCAHEWDKVDIKEAAMDIICRDADVLIETIEFLELPEECVAEIIRRDDLGVSSELKLYYAVKRWGEMKCEREGLDPLKNENLRSTLRNLVGTIRFPLMDQEEFTLNVGVNNQILNMEDMVAILLYFTVPKEKRSGIPPGRFKSNPRVRNRERASSSASNDCQILGSYNSNQSDLGAAYVSAARQAPANDSFPDLRDLIAATRRQHIGSSHDSSHEEILKAVLNNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTQ4</accession>
    <name>A0A1D2MTQ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000541">
        <property type="protein sequence ID" value="ODM96423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTQ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MTQ4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF32">
        <property type="entry name" value="HEAT SHOCK PROTEIN PDR13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="332" mass="38092" checksum="6948BC4340926FFA" modified="2016-11-30" version="1">MNPVPDVSSSSLLCPAAKKTAFKVAYGDNEFHPRKTIGKFIIDLNHENDHPCVFTVHFSLNIHGMLSVDKATVDQVVGLHIGETFSIMDLNSDEEMPAGAADLLEVGASTEVPREEHSSIRDVPVDSRPVHGLSRSELEAMILEESRFVALDKLEEERQARRTNLVATMLCMKGVLDGYLKRFVNEEQDRLDEYFTNLEHWLSHEGKNVDGEAFDQKLQDLKEKVDPIKVREALYRYRKTLSDAEEAVKAYRAKRPKYAHNADLDEDDKEQISKSIEETEDWLELEEQYSPPDTFSVINNDEEAQLRSKRIEEQWLICWKNARSILNSWKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTR1</accession>
    <name>A0A1D2MTR1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Transient receptor potential cation channel subfamily V member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_10228</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000539">
        <property type="protein sequence ID" value="ODM96433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTR1"/>
    <dbReference type="STRING" id="48709.A0A1D2MTR1"/>
    <dbReference type="OMA" id="CDEYYGE"/>
    <dbReference type="OrthoDB" id="533508at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000181">
        <property type="entry name" value="Nanchung, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF28">
        <property type="entry name" value="NANCHUNG, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="707"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="535"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM96433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="836" mass="94493" checksum="03F7AEB7FAB04E90" modified="2016-11-30" version="1">MGNANSNVTEGVKAQAGVCNQKLYTLVNLKGEGILVDLTKQATTTKNYAALDEAIKTKVEPFLYNKGEGKLFHITSIVLMRNKSRPKHKQLLKNEADYDNWKEPVSKDPKMYRRVCWRMDELGAVGESLLHLCLLCATSVHAELAKRLIKFYPNMINDIYMSDEYWGENVLHMAIVNEDFPMVKFLVDNNVNLQERCTGAFMGPEDQKSSRSDSLEYEWIDRDPNTNYDGHVYWGEYPHCFAACLGQEECYRLILAKGANPNAKDTNGNTILHILVIHRKQQMFDMAYELGAELGPTYRNNLNLTPLTIAAKLARKELFFHILNIEREIYWQIGSVTCAAYPLTQLDTIDPITGGIQKESALNLIVFGETTMHLDLLEGPVMDLLHAKWNTFVKFRFYRQFVAFFSRPIHAKKVIIPKSVNATFNSTAYFPNQSNIEIANATLLAQQGINLTTLLALASDPVIFDMNETSIMNASDALSTMLVSWGNVTDISANGSLLSVNGTSINGTIGKTLWFTWSKCLEQPTDNTQWARLTCECLMFLGAIAFLLGALRECQFLGASMFFENLATCPSRVLFLVSCHLVILMAVLRFLCLPEVEDLVAVVVMMTTAPFFLFFCRGFKTVGPFVVMIYRMLSGDLLRFVTIYLIFVMGFSQAYYIIFLSYKSQSENPLGTPAESVVSMFMVSLSSFDTMYEAFKLTSHDKIAKILFSIYMAIVAILLINMLIAMMGNTYTKIAETANEWQRQWARIVLVVERGVSPKARHHNQGLYSQPMGDSTRALVLRLNQSEDEKEEMRDLLDLRRYHDKAVARRMNKLMATKAPIHRPSIANSLLSVKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUL4</accession>
    <name>A0A1D2MUL4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000502">
        <property type="protein sequence ID" value="ODM96789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUL4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17177" checksum="18566BC2985D1283" modified="2016-11-30" version="1">MLFDHFLRFSPADDVASIVGKFAALMCTVLIIVGIVSGLAYVICYILYRSWSQNHPGGDARKCRFCFPHNPDDNLKCIYVHNFASHPGHQQGSFQEAACVIAQSSVNGNNLVVNKPSAEKEYLPLTKSKQGEITVAASPVIGLSEAPPSQLLNKVNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWW6</accession>
    <name>A0A1D2MWW6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ileal sodium/bile acid cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000441">
        <property type="protein sequence ID" value="ODM97448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWW6"/>
    <dbReference type="STRING" id="48709.A0A1D2MWW6"/>
    <dbReference type="OMA" id="AWMAHFR"/>
    <dbReference type="OrthoDB" id="203097at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361:SF28">
        <property type="entry name" value="P3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="479" mass="52327" checksum="893F678766919F9B" modified="2016-11-30" version="1">MCPLWPAHYILMYIMMLGPLWLMSFQMVGAASQAMSKYDVTFEPDTVKQLLIGSVSTVDVKFKRTELSQEGDKDIVNVVYYARDKNIASISPELVSTSDIVEIQNGTFSSKVNITGNFIGYTEICAQGVDANNMTVQETCMDVSVIRVARPIDKAFTYSVAALVAIIYINMGAALDTTTIKATLKRPIGPIIGFFSQFVIMPLLSFGIAKALIPLPALQLGLFITGCSPGGGASNIWTLTLGGNLDLSITMTTISTFSAFVMMPLWILTLGSTIFSQANLKIPYSKIGTFAIALVVPLAVGIIIQRTLPKVAKFLVRILKPFAVFLIIFIVVFAIYTNVYLFKLFTWQILVSGMLLPWLGYILGGGTAFLLRQNWRDVLAIGIETGVQNTGLAIFALRFSLPQPDSDLTTVMPVAVAIMTPALPLLLMLFQKLFCKSAFQLKEERKEPLFSVIEDSSIHSHNGSFVGVGGYQPAPLYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXX6</accession>
    <name>A0A1D2MXX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Netrin receptor UNC5C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000406">
        <property type="protein sequence ID" value="ODM97828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXX6"/>
    <dbReference type="STRING" id="48709.A0A1D2MXX6"/>
    <dbReference type="OMA" id="VFASKHT"/>
    <dbReference type="OrthoDB" id="5973910at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005042">
        <property type="term" value="F:netrin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008045">
        <property type="term" value="P:motor neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08781">
        <property type="entry name" value="Death_UNC5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037936">
        <property type="entry name" value="UNC5A-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033772">
        <property type="entry name" value="UPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000906">
        <property type="entry name" value="ZU5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12582:SF47">
        <property type="entry name" value="NETRIN RECEPTOR UNC-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12582">
        <property type="entry name" value="NETRIN RECEPTOR UNC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00531">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17217">
        <property type="entry name" value="UPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00791">
        <property type="entry name" value="ZU5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00005">
        <property type="entry name" value="DEATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Death" evidence="7">
        <location>
            <begin position="341"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="412" mass="46225" checksum="3E5D095AD6EB2E76" modified="2016-11-30" version="1">MRALKAKSYESTYFISTYTTNLFADGQTLLSPVLSCGPRNVSLKKPAILSFQHCAALKYGGWMISLYHYEQETLSSSSSASSDNNYRCWKKLVTIGEETIHTPVFLQLDTNQVFLVTDRLEKFALVGESQTGKKAVKTLRLAAFAPAQVNPNSTTEYTIRVYVLDDTTAALERVISQEKSMGGRMLDKPRSLLFQDGGDNLCISLEDVGAGWKCKGSYQELEFGRVWGCRQSNLHCSFTLEKTERKISAICFRLLAYQHVNLQKLTFRIRTEVGSMKSRSNQAMGVSNSSPEVTMAPRSSTVTTSSGCSSMATLEPGSPLSRLPQTLKKRLCHCLDQPHPTGKDWRLLAQKLGVDRYTNYLTLKPSPTEYILDLWNCRNRTPEAITDLLNALRLMERHDAVSILEKEMGPWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYA1</accession>
    <name>A0A1D2MYA1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000387">
        <property type="protein sequence ID" value="ODM98037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYA1"/>
    <dbReference type="OMA" id="NEFTGYE"/>
    <dbReference type="OrthoDB" id="10023262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="316" mass="35767" checksum="556A4709B1D8CE70" modified="2016-11-30" version="1">MTRFQEEWLHDPNLREWVVKVTNDESKVYCRWCSIVLRAHKSDLTGHSNTQKHAKNAASAQVTGANTGPISVQIVQQDPNSDIRMRSPKKNDKDPMFGSASAGTPVRPQYTKRYRKEWEEIDELKSWLRPYDSDSSKAYCRFCQCVLRAHRHDLVLHAKSSRHKRTEYARANGHVISGQMGISVSDGEMDVSAADSNDHDLSELDSKRARLDDVNAIEHIEIPGCAERVDPDDEHYGQISIMTTTSDDGKHDINVIKVEKDTSYLSHMDAGGIHGMPSIQPRRRKMNASKVIQAIQNNEFTGYELLQIVKCAVPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYI4</accession>
    <name>A0A1D2MYI4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative 18S rRNA (Guanine-N(7))-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000381">
        <property type="protein sequence ID" value="ODM98106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYI4"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="1">
        <location>
            <begin position="47"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12320" checksum="EDF46CF6BDC7A347" modified="2016-11-30" version="1">MAQARVLGLTEVFSSIFQSQRKEDEVVSGSTVGSTVFFARGVDEAPVATVSYAKRQTNHQRNKNDLKTRTAPKFSREWILEKKERRARQGKDCATGYKIHARNALIDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ50</accession>
    <name>A0A1D2MZ50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000364">
        <property type="protein sequence ID" value="ODM98327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ50"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="81" mass="9139" checksum="68391B6F4AC88BC8" modified="2016-11-30" version="1">MDRELLYSSPPPSSNSNLFSFGSASSLIHESVFVVLQTKIETLNKCSQAVELEWEEICQFPLKFLLNEMSPSRLLQPSDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N005</accession>
    <name>A0A1D2N005_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Transmembrane emp24 domain-containing protein eca</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_08057</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000339">
        <property type="protein sequence ID" value="ODM98627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N005"/>
    <dbReference type="STRING" id="48709.A0A1D2N005"/>
    <dbReference type="OMA" id="GATCAWQ"/>
    <dbReference type="OrthoDB" id="3427at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904820" evidence="11">
        <location>
            <begin position="23"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="12">
        <location>
            <begin position="32"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM98627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="25257" checksum="1A2ED84AEBCC28AF" modified="2016-11-30" version="1">MWNSVALSGLVVFCLAVSTVNSLYFHIAETERKCFIEEIPDDTTVIGIYKVELFDPRTGGFMPSSPGIGMHVEVRDPDDKTILSKVYSSEGRFTFTSHIPGEHVICLYSNSTKWFAGSQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRVRQLLDQVEQITKEQNYQRYREERFRQTSESTNQRVLWWSIAQTVVLLSMGYWQMRHLKSFFEAKKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N046</accession>
    <name>A0A1D2N046_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08016</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000336">
        <property type="protein sequence ID" value="ODM98663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N046"/>
    <dbReference type="STRING" id="48709.A0A1D2N046"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904798" evidence="7">
        <location>
            <begin position="17"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="169"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="672"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="704"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="732"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="786"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="797"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM98663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="811" mass="88463" checksum="52B01276D0259C33" modified="2016-11-30" version="1">MLKILTALLLIAAVCGSSKISSDLNSSLHTGEQLNIIVSMHGGTTSTLRRIEYQRISNRELRLNALHEALVANSEQSQRSLLKLLSSRNVEFKSIWISNKVYVKNADREIVHLIATDPEVKCIDMEQIVPLHEPVESKQTSAPLQDENQWGIVRIQAPEAWREPGTPNGSGVVVANIDTGVSPKHEALRDNFFGEYGWFDPLTETDFPFDGAGHGSHTMGIAVGSHGIGVAPGAKWAACKACGTMCMQSNLLLCGQFFACPTLTNGSNPDCSKAPNIVSNSWGGMGGNPWFYEVLDAWHLVGIIPVFSAGNVGPECFTVGSPADQLATIGVGSTRDDDAISRFSAVGPSIEENRMKPDIVAPGQDIVSASHLGNETYRLMSGTSMAAPHAAGTIALLLTRNKALSFDDVKNLLLGNADQNLTFNGTVCEGLQDNVFPNYVFGHGRINALKSVRAQSLAMGHHDISISVLGNPLTRRQFAEIRKRLEQAAEEQLNSEDLIKQADILIQEKYEEKNLTYYRGDDKSLPVFISWGLNNVAKKVHVLLRGEDYLNPQDEHTFIVLKQSSDPNQYTVHSAYIDNVNKIATSAIQWFGNLVEQKKNVKPLLEQMGNNEVQARSIRSSRPLCDWIGFLLLCDGPKNVKPIRKERVYPLPADIEDTDPLVPWMVGGSEEEGAAQNDAGAPKAKRQLPPNSGPVVPVATPVFSAPKPSGSSSGSKAASKILSSSGKSKVKVKAEASKAEVLDNSLDREVKEEKVVVAKPVKQEEEISPPAAKVKEPEGRSFGAYEPKKQTEDSSSSKKKHKRKHRKHMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1C8</accession>
    <name>A0A1D2N1C8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ATP-binding cassette sub-family A member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_07652</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1C8"/>
    <dbReference type="STRING" id="48709.A0A1D2N1C8"/>
    <dbReference type="OMA" id="TEMIAPF"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000335">
        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056264">
        <property type="entry name" value="R2_ABCA1-4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23321">
        <property type="entry name" value="R1_ABCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="285"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="13">
        <location>
            <begin position="709"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="651"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="806"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="845"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM99030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="956" mass="107774" checksum="A91E2AFB26ED1DD6" modified="2016-11-30" version="1">MTGVGPLTYWISAFVFDYFLLFLVVCVMITCFPIFQSYGIFTTHGGAGVAFVILMVYGLSAIIYSYLFSLYARTVAGGVALVALIHIISGVVFGYIVYFLEIIGTSQAGLLDTAARFRWAGRLFPTFGATMSTMRYIEIASKNGRCNLLSDEAKDFLCNPKSINLPPSLRECCANCKKLGVSCFKPITYISWIHKREALLGPATTKDMVELPGIAQELFFMLIMALIYLTVLMLLEYRIVQRFFEMICQSKTTVFPNTVRDDDVMAEANRVEEMVKNGNVNEDALVVKKLCKSYGSFAAVSNLFFGVHHGECFGLLGVNGAGKTTTFRILTGDETRSAGNVYAFMKSLDEDRIEFLSNIGYCPQFDGIVGVLSGKQMLQLFGRLRGVLAMLANVQCEKYSGGMKRRLGVAMAMIGEPQILLLDEPTSGVDPVSKLQFWNILDSVRDAGQSIILTSHSMEECEALCSRLGIMVNGQLQCIGGVQHLKHKFAQGYTLSIKLKLHCPHTEEQNLDTLKKEIDEKFYPCTLKDIHQNVFQYQLHNTALEWDVVFKTMEDLKQSYSELIEDYSLNETSLEEVFLAFARNQTPNHINVENMEVRGTTQQPQRRFARSGAVTVTCDEPVAGPSRLSQLQQLFPAKGYRKEVVNVAVEDTDSPPDLGPPEAVGVSDPLPRSRSLSVQQPQVKPPASQKRKWTNQLNYLMKEALPFVVRQKAAQTFLNPIDPVELEHSDYFDFIKHPMDLTTIRQRLRNQFYKSASECVSDFQRIVCNVHVYNGHESQAFDDAELLENIFMESLVKMPQPEVELPVPLRGGPRKRKRCSTRSEDRSAGNIILPRVEKLVKKAVESLKPEGPRRRRRAQKASDSDASTDSDDEALSFAELRRLKQVQFLSRQLENTATQLRLVCTEDDGMVEEVYACVDRQIKLAEKQKEWLAIDTMKKFAHKLRKEKDHHDSDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1F9</accession>
    <name>A0A1D2N1F9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sn1-specific diacylglycerol lipase alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000301">
        <property type="protein sequence ID" value="ODM99070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1F9"/>
    <dbReference type="STRING" id="48709.A0A1D2N1F9"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904877" evidence="2">
        <location>
            <begin position="20"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="64" mass="7642" checksum="565EF593DADD6FCC" modified="2016-11-30" version="1">MLVICTCFVILSLVITAWCTYDVAGRSWVKMKRYQANMKEMDRKQAKRSGSRHRNWRQRLTSCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1K1</accession>
    <name>A0A1D2N1K1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000295">
        <property type="protein sequence ID" value="ODM99176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1K1"/>
    <dbReference type="OrthoDB" id="10546069at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904892" evidence="1">
        <location>
            <begin position="23"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="17160" checksum="966F9DDBE79A6E63" modified="2016-11-30" version="1">MENFAKFCVLVVFVLGAATVRSDDDAEECKKMAKQYFKRIHKVYIDCHADVKQNTSSIEEQFEKLGCTVKCILKNDKMLDDNDMVTDDLLKTTYKDRVTPKYEDKLLTKFMDCKTKFGDKLDKTDEKCVGFKNYGLCMQEALSHVCYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1U1</accession>
    <name>A0A1D2N1U1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-glucuronosyltransferase 2B19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_07807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000315">
        <property type="protein sequence ID" value="ODM98865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1U1"/>
    <dbReference type="STRING" id="48709.A0A1D2N1U1"/>
    <dbReference type="OMA" id="NIMLEYP"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000021">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="39195" checksum="83AB29B950E93A64" modified="2016-11-30" version="1">MIKETCEKSYDLPIVKSLLNEKFDLVFIQPMFNECIFGLIYRMQIPFLLFTPTTIPSWVAGKVGGNFPSSITPNIMLEYPPEMSFFQRFLNLGMDTVAEVYMSLWYEPMIEKIYREKLGEDIPSVAEIYTNASLVLSNGHFSLFPPKPYFPDVIDVGGIHSRPGKPIPKDLEDFISQGKDGFILFSMGSAIKGDMMPDTKRKMILNVFSKLKQQVLWKWESETMPDLPKNVKLVKWLPQQDLLGHKNIKMFITHCGGGSTEESIYHGVPLIGIPMFADQPHNADLAKKHGFLVQLDWNSLAEENFSAAIQAILSDPKYLSNAKKISALFKDRPVDALELGVYWIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1U9</accession>
    <name>A0A1D2N1U9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000290">
        <property type="protein sequence ID" value="ODM99266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1U9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17965" checksum="DB5BDC7C399E7E64" modified="2016-11-30" version="1">MENVQHIQTGRRVGYLDLVASIIHFCYVVVDLSVFFKDINTNIRTGMAIFKIIALVGGVWLSYMLIESTQKDSIKNANRYAQIWVSGKTSIVAFFLIIIIRFFANGRPIYQKELKEFRYPAEAVSTIVLTITFICLAYPYIKELMELRKLEKDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2F2</accession>
    <name>A0A1D2N2F2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone H3, embryonic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_07595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000300">
        <property type="protein sequence ID" value="ODM99085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2F2"/>
    <dbReference type="STRING" id="48709.A0A1D2N2F2"/>
    <dbReference type="OrthoDB" id="4025405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="3">
        <location>
            <begin position="121"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="172" mass="19239" checksum="04C08675EEB48586" modified="2016-11-30" version="1">MLCFQLRVNASAALHAEDRIQAKHLPSFMVLRYVRTLEEKVLEKEPLAHSSWQSSQNQIRKRLVRRNQKPRAQAAGSPKKAAKKPAAKKAAATPKPKKAKAPKAAAKPKAPKRPTRAAALKASKALQQDSEAYFVGLFEDSNWCANHANRVTIKPKDIQLARRLRGELYKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2Z2</accession>
    <name>A0A1D2N2Z2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_07022</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000264">
        <property type="protein sequence ID" value="ODM99657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2Z2"/>
    <dbReference type="STRING" id="48709.A0A1D2N2Z2"/>
    <dbReference type="OrthoDB" id="10059102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000047">
        <property type="entry name" value="Trypsin eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF11">
        <property type="entry name" value="ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="17"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM99657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="251" mass="27110" checksum="3108DB2AA6B30295" modified="2016-11-30" version="1">MVFKQSPSIKGKDQPLIIGGSKTADGELPYQILLQHQGQYICGGSFINVNGTHFVLTAAHCVGTRHPSRYTVVAGETDRNTASGNEQLRNVKTVFRHGQYSSRTLQNDIALLAIDEPFEVNEFVSPIPLPKQGQDTTGEVVVSGWGYITPIGIASRYLKKVTISVIDNLACKAFYAIRLLYVTNSMLCAGRVRGLSDSCNGDSGGPLTTVDGGYLAGIVSWGTLCALPLQPGVYTQVSHYIDWIELQASSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N475</accession>
    <name>A0A1D2N475_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tropomyosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06607</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tropomyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000235">
        <property type="protein sequence ID" value="ODN00069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N475"/>
    <dbReference type="STRING" id="48709.A0A1D2N475"/>
    <dbReference type="OMA" id="QYNDANT"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000005">
        <property type="entry name" value="Tropomyosin alpha-1 chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000001">
        <property type="entry name" value="Tropomyosin alpha-1 chain isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19269">
        <property type="entry name" value="TROPOMYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00194">
        <property type="entry name" value="TROPOMYOSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="13"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="268" mass="30883" checksum="CF1C0E1E33E4061C" modified="2016-11-30" version="1">MPKTRQIIWSRQLEMQISKVQRGEEELDNLKKRLSQLEQEYTTIQETLAKVNTNLEAKEKALTATEMELNALGRKVQQIEETFENTEQKLKAATDQLVTVQHAGDESERMRKVLENRSATDEERMKSLEAQLKEATALAEEADRKCDEVAQKLAMVEQEVEIAEDRANTGEMKILELEEELKVVGNNLKSLEVSEEKARQTEVEFKATIKNLSAKLKQAEARAEFAERTVQKLQKEVDRIEDELKNEQEKFKSITNELETTFSEMTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N656</accession>
    <name>A0A1D2N656_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">28S ribosomal protein S17, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05934</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000188">
        <property type="protein sequence ID" value="ODN00748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N656"/>
    <dbReference type="STRING" id="48709.A0A1D2N656"/>
    <dbReference type="OMA" id="TVHAKWI"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039193">
        <property type="entry name" value="Ribosomal_uS17m_metazoa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24088">
        <property type="entry name" value="28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24088:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="20222" checksum="3562C4EC3527B452" modified="2016-11-30" version="1">MASTATSLASSGLKLVTNTGPKKFLLGKCYPCYVPKATRVYVKMMDWDDWLKMYFTRFDTFFAHDPDKITKTGDIVLIEQLPKRLTRDITHAITKVVYPMGDIVDPITGKKCMGGNFREDEEKKDRLWGKNKNAFDYDKAPPRGWQEGKKDWSHKPGQTKFHEFTDRDITHLTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6G5</accession>
    <name>A0A1D2N6G5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Atherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_06007</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000193">
        <property type="protein sequence ID" value="ODN00675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6G5"/>
    <dbReference type="STRING" id="48709.A0A1D2N6G5"/>
    <dbReference type="OMA" id="XRITSET"/>
    <dbReference type="OrthoDB" id="10004495at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050548">
        <property type="entry name" value="PcG_chromatin_remod_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048589">
        <property type="entry name" value="SAMD1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247:SF139">
        <property type="entry name" value="ATHERIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21524">
        <property type="entry name" value="SAMD1_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52014">
        <property type="entry name" value="SAMD1_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SAMD1-like winged helix (WH)" evidence="14">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="447"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="183"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="269"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="323"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="560"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="560"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="592"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS52014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN00675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="704" mass="78423" checksum="E4689C0D70956219" modified="2016-11-30" version="1">MTTDQLRNVILEAVDCLRQRKCRPDRESIAVYVMRKLGSSMNEIFSEIENVVDQGSLLKVEYKGSTSYRSPKSFDVKNSPLLTKHSKILNSSKTTRYVISGINELLSTFPNYIKDGVPYDELKKKLIEFDKERFVESGIKVIFEREEGAGNIYVAHSEDPIDPIRIFPKDIQVPEGMKLISFCEEANPTPERKKRKRTKKEEATETNDEKQETEESSTNGSPDSKRLVYAVKSDPHKISENGSSDKAAKTKAEQISSIGFKLIAEKAATARKVNSVKSKAKGKNGSSVPDSTSNNTSEHDIKVKSECDRKPCLTLLIHETDKVDSSKRKEIVNGVEKTPSTSSPKSKGKLPAKRKLVTTESPVGGNSIASVKGKKQKLSTPVKIENEPDDLQLLRVNHEPPRFTYAFKRRSYSSNCSSSSQSTIATEEVTLPDLLESSDSIANGERVEECVYCRKEKNSIGDSEDFLSCGSCNAKIHPTCIDYSEEQAKRLRTNSKSSEPHLQWQCFSCKRCGVCQQALMSSKSCTEVPKKNGDKSKILKKKEGRYILCDRCDKAERTVKKQVSKGKKTGRQSVVQNDETNSVLEVKEEPVSDSSAEDSSTSTASCSTPKKTEIPDISSWTPTQVQKFFSEKGLQDEAASLREQEIDGMSLLLLRRADIIFGLNLRLGPALKIYRLVSQLQQNSTALKKKIGENSGSKRSDVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N976</accession>
    <name>A0A1D2N976_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STING ER exit protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04874</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STEEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N976"/>
    <dbReference type="STRING" id="48709.A0A1D2N976"/>
    <dbReference type="OMA" id="HVTFVMF"/>
    <dbReference type="OrthoDB" id="418131at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029704">
        <property type="entry name" value="STEEP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057965">
        <property type="entry name" value="STEEP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46355:SF1">
        <property type="entry name" value="STING ER EXIT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46355">
        <property type="entry name" value="UPF0428 PROTEIN CXORF56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25809">
        <property type="entry name" value="STEEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STEEP1" evidence="3">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="24928" checksum="15778D7391657212" modified="2016-11-30" version="1">MPKVVSRSIVCSDTRDQEEYSGDKPLLTYYCLCGQMTLIIDCALDNLPLRKRDGARVIDGTKHAHKITSDPDETVFLKRPDGIEKQHRLKCKRCGLLLYYMHNVVGNVVFIVRGALTSTGEGPMGSNIYKQVATEQEHKPIMVTKHTKNMGKFSSVTVSTIDEEEDEIEAREIADSYANNARIIEKQLVRKGMNKRKLIEQAQQEMEAKKSRVRGTLIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9Q1</accession>
    <name>A0A1D2N9Q1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_04719</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Zymogen granule membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000132">
        <property type="protein sequence ID" value="ODN01978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9Q1"/>
    <dbReference type="STRING" id="48709.A0A1D2N9Q1"/>
    <dbReference type="OMA" id="CMEGMGT"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042589">
        <property type="term" value="C:zymogen granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000001">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000003">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000004">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002391">
        <property type="entry name" value="ANX4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF177">
        <property type="entry name" value="ANNEXIN B10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00200">
        <property type="entry name" value="ANNEXINIV"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 10" id="KW-0041">Annexin</keyword>
    <keyword evidence="4 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 10" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="322" mass="35974" checksum="C34F3BE2E6C9BE7C" modified="2016-11-30" version="1">MAEHFYEPTVKPFSGFNASSDAKTLRAAMKGLGTDEDAIIDILTKRSNPQRQEINTAFRTEFGRDLIEDLKSELGGKFEKLILALMEPPVVYLAKELHNAMEGFGTDCDVLTEILCTRTNDEIKQIVETYEKTFGQSLENAVESEVSGDYKSLLILLLTVGMRGVREEKAIYPDKAKEQAEKLFAAGEGKWGTDEEVFVVVLAHQSLPQLRLVFKEYEELSGKTLEDAIASEFSGKLKSAVLTIVKVAKGRSLYYAEKLETSMKGIGTDDPTLIRIIVSRCEVDLGIIKKVYQQTYDRSLYEAVESETSGDYKKAILNLIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA89</accession>
    <name>A0A1D2NA89_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHK kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000122">
        <property type="protein sequence ID" value="ODN02157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA89"/>
    <dbReference type="STRING" id="48709.A0A1D2NA89"/>
    <dbReference type="OMA" id="MYAVEIN"/>
    <dbReference type="OrthoDB" id="8250698at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="2">
        <location>
            <begin position="162"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="458" mass="52215" checksum="553F75E5BCF1DDD3" modified="2016-11-30" version="1">MSQVKVEEEIQSAQNDGAAPTAPGIPEPEIKPEDVITPTIISAILDGYNHPELSLVDFQAKQGTMAGDNYMSIMYSLNINLKNATSGDSQALPVMLKVLPRNEFRLKMIRDANIFVRDVNMYKMVLPSMEEFQKKAGFEADEIIRPWPTCYACKTDGENDFLAMEDLKTQGFKMANRKEGLDFDHSKLFVTTLAKFHAISFAMFMGEFDAILEKYPWLEESMYNEDKIPDTFKLFIEGTFTQHANMLKEVGEEKAGTLVGKICNADYYKHLFSLVGGKVPFAVIGHGDCWTNNLMFRYDPETNKPVEIKFVDYQVSRVSSRAVDIHYFLYTSPQVNVLNEKEDEILKVYFDEFTKFVRKLGVDTDAHGLTKEDFDQEIDKFRFSGVISGLMLASIMSAESADVPDMESLKEEDFTVNNGEDAMKNLFLNMLKERAMEKIKNIANRHLPRCAEMKQYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAR0</accession>
    <name>A0A1D2NAR0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Follicle-stimulating hormone receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000115">
        <property type="protein sequence ID" value="ODN02344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAR0"/>
    <dbReference type="STRING" id="48709.A0A1D2NAR0"/>
    <dbReference type="OMA" id="FEYPETH"/>
    <dbReference type="OrthoDB" id="5981530at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10689" checksum="59416724E45DD19A" modified="2016-11-30" version="1">MLDLSETKITYLPTQGLSGLESLRLEKVWTLSVIPSIYHFEANLIFVHTNAITYVLEEAWLTWPYHCCAFEYPETHDPAAFQKYQYVMNWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC97</accession>
    <name>A0A1D2NC97_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative peptide chain release factor C12orf65, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC97"/>
    <dbReference type="STRING" id="48709.A0A1D2NC97"/>
    <dbReference type="OMA" id="NKRTNCC"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="141"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="266" mass="30460" checksum="273327FF798F0162" modified="2016-11-30" version="1">MSRVKGALKSIVYSKISGPATSADCDEVIPLGGSHTESHEFCVSVCDHAEKTRYSSSVQEAFEILQQPKYTDKNYYQDRIRGEFWRNRELTESEEVQFQFQRQLQHTSLSASPFKFGIDNLYPYQFRRKHSEIDTSKVPILNEDDLEEWFIKGSGPGGSNVNKRTNCCSLRHKPTGIILKCHLARELNQNRKLARQMMIEKLDEHFNGDESIAAQKKRLGLEKTHAQEVKAKKVFEMKKRYKDLVHPAEAASDDGSARETSSEKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCR6</accession>
    <name>A0A1D2NCR6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CKLF-like MARVEL transmembrane domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000088">
        <property type="protein sequence ID" value="ODN03053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCR6"/>
    <dbReference type="OMA" id="NHKKGAE"/>
    <dbReference type="OrthoDB" id="10028364at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050578">
        <property type="entry name" value="MARVEL-CKLF_proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22776:SF49">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22776">
        <property type="entry name" value="MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51225">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="7">
        <location>
            <begin position="31"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="19562" checksum="C78AF0A82C0A2B43" modified="2016-11-30" version="1">MDPESALPSTHRTYTTTTTTIDTTVRFDPSYVRSLPGTLKVGQLVLNLLGFICVSVARNSRAHNANWFSFVSMGGFWITLILLLLFLFHIIEKLHFIPWLLAETVYCAIWTFIYFTAATAVSSMSNYEGVFIAAAVFGYIAMLVYGFDAYLKYISWKAGELAQGNRKTTTTTVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND06</accession>
    <name>A0A1D2ND06_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND06"/>
    <dbReference type="STRING" id="48709.A0A1D2ND06"/>
    <dbReference type="OMA" id="YLESWVF"/>
    <dbReference type="OrthoDB" id="5953636at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016768">
        <property type="term" value="F:spermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000197">
        <property type="entry name" value="spermine synthase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015576">
        <property type="entry name" value="Spermine_synthase_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315:SF1">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="138"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="42851" checksum="80F08F8BF4E237E1" modified="2016-11-30" version="1">MGSQNLAKSGTILFDFPVPPTDVTDENGMNKVENAVVSVLAPHFGDLKQVSKHEMTSKGERVGEVRLYVEGSNGVTMTLRIYNDTFLVTATVEYDKTVLVDALSYDEIKSLEQKMIKLLNTEKKTKAMPELKRGLKHDIYFNTSDDRILEYDIKKMVYEKQSEFQHVQIAYSENYGNILVLDGLMNLAESDLIYTESLMWKGKMDYKGKNVLILGGGDGALLHELLKEGPAFVTMIDIDDTVMQQCREHLRSACGTTLDTYETDKYQVIVGDCVAFMKKCIESGRKFDVVFGDLTDIPISPIPQGEIWDFVLQIIQLSFSILEKGGVYMTHANGVSSKESLKTFETAVLGHLARPVSFTTLENFVPSFMEKWVFYQIKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND22</accession>
    <name>A0A1D2ND22_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_03561</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).</text>
    </comment>
    <comment type="function">
        <text evidence="11">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
            <location evidence="2 11">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the ARPC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND22"/>
    <dbReference type="STRING" id="48709.A0A1D2ND22"/>
    <dbReference type="OMA" id="TPSKWWL"/>
    <dbReference type="OrthoDB" id="442863at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1760.10:FF:000001">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="20146" checksum="69D8DD951F63000A" modified="2016-11-30" version="1">MAYHSQLPSNKNVGNMAILPIRTTVRGPAPMQNGASEQDIIDEALYYFKANVFFRNYEIKSESDRLLIYVILYISECLKKLAKCTNKNQGMQEMYTLAISKFDIPGDPGFVLNSVYGKPGNSNDAEFLRSYLTQVRQECGQRVCEKVFNTEDGRPSKWWLCFAKKKFMDKSLSGPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND81</accession>
    <name>A0A1D2ND81_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">D-aspartate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03627</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000088">
        <property type="protein sequence ID" value="ODN03045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND81"/>
    <dbReference type="STRING" id="48709.A0A1D2ND81"/>
    <dbReference type="OMA" id="TDPTRHM"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905388" evidence="8">
        <location>
            <begin position="18"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="9">
        <location>
            <begin position="3"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="311"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="348" mass="38617" checksum="98CEFCD9C7D57418" modified="2016-11-30" version="1">MVRIAVVGAGIIGLSSAICIQKSVPDAKITLITEKLSPHTTGDGAAGVWSPYLLGDTPEKDVYRWAKATHDFLREQWRTEDAGLRGISMLPVMRVASEVEAEDPLWKDIVFGFRRMRQDELTVFRKPSLKTGYSFVSFTCEASKLLPYFLELFKSSGGTVVIQRVDDISSLQQEFDIVVNCTGIQANRLVPDPLVQPKRGQVMRVEAPTLKWAVLDDDDDGNYIIPNQDLVVLGGTHQEGDWNTEVYPEDTVHITDGCFRMVPSLKHAPVHKEWVGLRPGRPAVRLEMERIGISSSPGKIPFTVIHNYGHGGSGLTLFWGCALQTTDLVKNALQPNYESIKSGLRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE14</accession>
    <name>A0A1D2NE14_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_03164</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE14"/>
    <dbReference type="STRING" id="48709.A0A1D2NE14"/>
    <dbReference type="OrthoDB" id="426657at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051657">
        <property type="entry name" value="RNF168/RNF169_E3_ubiq-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23328">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23328:SF0">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="37"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="268"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN03493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="552" mass="62684" checksum="C974D245BE633F21" modified="2016-11-30" version="1">MDNIAGAKRPRKQFTEESEAIGIADKPGKLTREDVTCPICWSILYEPTTLPCKHSFCIKCLKRHVEEASIHCPCCRCRLGIWSRRVSKSQTHLDEPLWNRIQAEFPKLVEARLKDLDSPDILEDEWSPLFEDHENTNPVRTIIDGTICTEPGEVRAELLQIQEEHEKDIERKRLLEEAASVELIRKMQEEEKNQRLTFNSSLEEEDFLFAKRLQSKLRKEDERFIAAAMPRRISSRIKRPVRRNLTEELDDVGNSSFDSFSSFSKTSRDSSFCEDQSPSRHTSAQAFKKRKKKPSCTVTSENVMENSPDICSKAYLLIPPKPVRKTPAFVAPAPVENFSVEFEAQAPVGKTYQVGEAEIIPGKENLEARSVPNLSFAELFNEADDKENLIDLTCSQEDPEINTTSQETSTSSNLSVCLNENGNDLVHQMTETMPSSSPVPPTPDKNFHSRIQEGMSIDMILNDSFNGLSPFGKVYNEVVLGEKEYECLILEGTALQAHKQKLEQEAQDRAFAKSLNSWLRLGLPSPGRSENMYRLRRSVRMETPVVGENNVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEI4</accession>
    <name>A0A1D2NEI4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat-containing protein 56</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000076">
        <property type="protein sequence ID" value="ODN03386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEI4"/>
    <dbReference type="STRING" id="48709.A0A1D2NEI4"/>
    <dbReference type="OrthoDB" id="433501at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040091">
        <property type="entry name" value="LRRC56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22708">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22708:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="600" mass="66237" checksum="9B8FB1B80404F0DC" modified="2016-11-30" version="1">MSRSGRSARSSTSQSRGLKSRLSSGGGDNPQSLDDELQTVLRKEYVEGLPGKEEAIQDVKTVLHEVSKEPSAAAMEKLMPRFLSSSSSPGSQSQSQMETKEKVRSKPKQSQQQTPRHAKLTARPGASATSKSSRQKSSRQTATEETHSLPHIPPKTGITDPDFTGMTTMTRLTTSDPTLPDTRYTPPTTSSGNARKENLLQTASSLSTATSIGEDVTTSILLPPGEMTEDEGTEEQDELPYTENLLEMPTDSDAEEIWRSDIVELTKIKSGPRGKMCGTDVLELKYKEPQWPHQLLLNQILARLPRLTHLILDGSELRFLRDLGSSLQSLITLSICDCGLRSLDGTYAFPNLRTLIARKNLIKIPTQASFLSRLSYLDLSSNPISSADEFGSLRHCSELRVLKLHDTPLAAEEPGFNKEIKRLVPQLKEIHPPRPDMLQFKQIKKEGHQMMSRADGESKQETKQNKEKKIKKEKKMMSSVPGMAYDDVMLDEPKPGIAYQKIAAKHQPDTKQNHDDDDDIKDVSLGTGDYSGVLMAPNFLQHLEEAMPPSTAEETVPVTPATPSENYEQYKMCGDGESIEKTKGRDGNASTRNHPGGDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFG0</accession>
    <name>A0A1D2NFG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFG0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905482" evidence="1">
        <location>
            <begin position="22"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="90" mass="9568" checksum="08F70B969D01F767" modified="2016-11-30" version="1">MASNTFIFLAIFASTVSMILSIPQLNQLPIREPIDSNNPVAPDAVPDNLPNINPRTFGSLFNLSAYLANAPTNSAALNFIPLITILSALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG40</accession>
    <name>A0A1D2NG40_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02519</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000052">
        <property type="protein sequence ID" value="ODN04192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG40"/>
    <dbReference type="STRING" id="48709.A0A1D2NG40"/>
    <dbReference type="OMA" id="INVSYNC"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000004">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF244">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="9">
        <location>
            <begin position="49"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="7">
        <location>
            <begin position="116"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="8">
        <location>
            <begin position="586"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="707" mass="78928" checksum="55A9EB2CCF24980D" modified="2016-11-30" version="1">MPVTGNPEANMSNGTVESNSVPEQENESQVVKPPSEISKNAYVKSLDEYEAMYKRSISDPEGFWKDILADFHFQEKQADDKSFLTYNFDINKGPVSIKWLEGAKTNISYNLLDRNVQKGLGDTIAFYWEGNDPKDESKITYGELLKEVCKFANVLKNLGVKKGDRVAIYMPMIMELPIAMLGCARIGAIHSIVFGGFSADSLADRMIDAQATVLITSDGVWRGEKIIHLKEISDKAIAKCGDSNLDVKHCIVVNHLPRLAVNKVDESTNQSPVKRKQFDYLTPFDETRDKWYHELIEKADDVCPPEWVDAEDPLFMLYTSGSTGKPKGVLHTTAGYMVYAATTFKYVFDYHPGDIYWCTADIGWITGHTYVTYGPLANGATSVIFEGTPFYPTNSRFWDVVDKYKVNQFYTAPTAIRSLMKFGDNFVKQCNRSSLKILGTVGEPINPEAWLWYYNVVGDGRCPIVDTYWQTETGGHVITPLPGATPSKPGSATFPFFGVLPVLLTEEGKEIEGPGEGYLVFKKPWPGMMRSVYGDHDRFEATYFKRFPGYYFTGDGAKRDKDGYIWITGRVDDMLNVSGHLLSTAQVESALIEHKAVAESAAVAMPHKVKGEALYCFVTLRDGFEFSSQLEGELKLKVREKIGAFAAPEVIQLAPALPKTRSGKIMRRILRKIAVGDSNFGDTSTLADESVIDLLLQHRPEAPAKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG63</accession>
    <name>A0A1D2NG63_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calcium release-activated calcium channel protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02419</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orai family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000049">
        <property type="protein sequence ID" value="ODN04263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG63"/>
    <dbReference type="STRING" id="48709.A0A1D2NG63"/>
    <dbReference type="OMA" id="WLIAVEM"/>
    <dbReference type="OrthoDB" id="61124at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015279">
        <property type="term" value="F:store-operated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002115">
        <property type="term" value="P:store-operated calcium entry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.140">
        <property type="entry name" value="Calcium release-activated calcium channel protein Orai"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012446">
        <property type="entry name" value="CRAC_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038350">
        <property type="entry name" value="Orai_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31501">
        <property type="entry name" value="CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31501:SF7">
        <property type="entry name" value="CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07856">
        <property type="entry name" value="Orai-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25297" checksum="DAFC1E55AF09FF3F" modified="2016-11-30" version="1">MEGHYWHTPPLQNQNHLHDRKRRRLMMTHSKIKAITETSAILAGFGMISLVEFQLKPDTGAPKELVVAFVTSTCWLIAVEMLALFIASFVFPNIEVSSKFSNIVKFMEEGEEPNEDLIDKLQCFVETAWFFSITMGICLFLINMSLICWIKYYDEDYGRTMGIIGTSITAPVVLALMILAVVIHRKVISHHYHDASRTIRELNIDAHLLDMGIQEFQSECGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGE3</accession>
    <name>A0A1D2NGE3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lachesin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGE3"/>
    <dbReference type="STRING" id="48709.A0A1D2NGE3"/>
    <dbReference type="OrthoDB" id="8049355at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF21">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 11, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="75"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="236" mass="26836" checksum="34B21FFCEDA2AB56" modified="2016-11-30" version="1">MKSVSWIRKEDSHIVTVDRYTFIADDRFQVMAAPPGDSWMLQIKYVQPRDAGFFECQISTEPKMAHRIRLNVLVPKIRMDTTEENMFVWEGSQVQLRCVVMNTLADNVGKVIWLRNGKILNKFDLSTSSTMLSFQAKLDGTKLTETLTFVGVQKSDGGNYTCSLENVGFSSVTLHVLSGENPAAMHHGRGITTTTSSQATTNFHQRHLNHNYHQNSFVTIVLMILVQRTLHYVCHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHP1</accession>
    <name>A0A1D2NHP1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenylate kinase isoenzyme 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHP1"/>
    <dbReference type="STRING" id="48709.A0A1D2NHP1"/>
    <dbReference type="OMA" id="PRANEIR"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="24461" checksum="59ABB352553FBDCB" modified="2016-11-30" version="1">MGNCCKKSKQSESEDSFDLKSAINGKKRICIWILGGPGSGKGTQCERLADRFNLAHLSTGDLLRKVCKEDTPLAQQFKQAMERGELVDTQALLQLLISAMKDAYKNFNGYLIDGFPREVEQGYLFSETIGMPHVIVSLEVPDDILVERLLKRGQDSGRSDDNEETILLRLRTFHNISQPVIDQWREKVVVIDGNRAADEVTQMCIEAILRLGSDFGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHY7</accession>
    <name>A0A1D2NHY7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Zinc finger E-box-binding homeobox protein zag-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_01859</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHY7"/>
    <dbReference type="STRING" id="48709.A0A1D2NHY7"/>
    <dbReference type="OMA" id="GKMSDQQ"/>
    <dbReference type="OrthoDB" id="7491548at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000013">
        <property type="entry name" value="Putative zinc finger E-box-binding homeobox 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000744">
        <property type="entry name" value="zinc finger E-box-binding homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000608">
        <property type="entry name" value="zinc finger protein 286A isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051574">
        <property type="entry name" value="ZnF_E-box_Homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24391">
        <property type="entry name" value="HISTONE H4 TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24391:SF27">
        <property type="entry name" value="ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 13 14" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Homeobox" evidence="16">
        <location>
            <begin position="479"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="17">
        <location>
            <begin position="823"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="17">
        <location>
            <begin position="851"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="17">
        <location>
            <begin position="879"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="13">
        <location>
            <begin position="481"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="47"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="208"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="318"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="419"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="588"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="779"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="422"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="621"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="638"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN04861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="913" mass="99270" checksum="9D456F15A117C222" modified="2016-11-30" version="1">MTEHVRIHSGEKPFECSNCKKRFSHSGSYSSHMTSKKCLIMNLKLGRNRNNDSKGSSGTPPSSGANISSPQRGSSSKQNSSTNRQQQPQAQGNIFTDPTFPGHPLLSAKLGKTPVAPPNDNNMVNHQNGTDLSAFPATPPPFLSPGPVNFHPFLMTAAAAAGLPPNPYHLNMTTFLNSLPHNSPLRQLATLDNSEEVLTKRAADLMNGMSSFDPNQSLHQLRDHHRQRSSLSSSNRSQISRSPSPNSCDESMSSSKPHDDRRSHHRGGDDEDAEDTEGKDKLDNNVQRLLHTVNANVTRQFLEACSMKNGYSVEKMLGSGGESSCDQMLSPGSSRPQSRFGDDEMDEEQSQDHEIHNNNNSIISNGSEELIKLNSSSHKRNKNGGVEGLAARLELCQNDPTAAAAAFGSKAAFSLFLHHHQQQQDKAKEFDKKRHKEDSSSDHQQRRHEEENPSSQSENESGDHHDNNNESSHETVEEGRRARVRSLFSESQLAVLRQHYAIDPRPRREHLLALAQQLALPLRVVQVWFQNSRARDRREGRPPQPVAQAFGGSKGLGVTGIPSGLSPLINGFSVPRLGLALPGWTINTSGGEMKEQQPSPQLPVNLGMNGNGEQPLDLSTKKSTPSNSPRPSMGISEPVTSDSEDTNGLSGFNQPLNLKTSPNSSPFAGHSTNSANCNGLKSSSPGILSSAQSRLAKILSQPPASPTIHTVYSGNQNGGGIVFDARTPSPAVSLGPMITPMLSGLIPVPSNSPHELHLNGFARSPINLMAGGGSENGDHTAIFLGMNGPPTKKRKSDGNVSIPKQSSGSGGSNNGQPEEPGQFACDQCEKSFNKQSSLARHKYEHSGQRPYKCNTCEKAFKHKHHLTEHLRLHTGAKPFQCNKCGKRFSHSGSYSQHMNHRYAYCKPNPNNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI39</accession>
    <name>A0A1D2NI39_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_01712</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI39"/>
    <dbReference type="STRING" id="48709.A0A1D2NI39"/>
    <dbReference type="OMA" id="CNKRKPP"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007224">
        <property type="term" value="P:smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22983">
        <property type="entry name" value="PROTEIN KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22983:SF6">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="4"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN04940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="233" mass="26729" checksum="4D64E69FFAE57389" modified="2016-11-30" version="1" fragment="single">MDRYQDLKEIGAGSFGTVYVCRIKNTETFVALKKINTRGKHAREIESLRQECEIQKNFKHPNIIRMLDAFNTDDAVVVVTEYAREDLARCKDRAPGKCLPLNEVQRIACHIVSALYFLHSHRILHRDIKPQNILLGWDGMAKLCDFGFAKAMAPSDYMLTSVKGTPLYMAPEIVNEKPYDHNADLWSLGCILYELLKGDPPFFTNNIIELVSKIRNKSIDWPQNTNDYCLSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIQ6</accession>
    <name>A0A1D2NIQ6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">15-oxoprostaglandin 13-reductase</fullName>
            <ecNumber evidence="2">1.3.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">15-oxoprostaglandin 13-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01520</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>13,14-dihydro-15-oxo-PGF2alpha + NADP(+) = 15-oxoprostaglandin F2alpha + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133374"/>
            <dbReference type="ChEBI" id="CHEBI:133409"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:50590"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+) = 15-oxoprostaglandin E1 + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57401"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133408"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:50586"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+) = 15-oxoprostaglandin F1alpha + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50592"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:79072"/>
            <dbReference type="ChEBI" id="CHEBI:133411"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:50594"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADP-dependent oxidoreductase L4BD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIQ6"/>
    <dbReference type="STRING" id="48709.A0A1D2NIQ6"/>
    <dbReference type="OMA" id="MISDYNT"/>
    <dbReference type="OrthoDB" id="809632at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047522">
        <property type="term" value="F:15-oxoprostaglandin 13-reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006693">
        <property type="term" value="P:prostaglandin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF7">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase N-terminal" evidence="9">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="8">
        <location>
            <begin position="156"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="334" mass="37337" checksum="D9D26B061A9A620E" modified="2016-11-30" version="1">MIAKKWIRQNDFQGLPKVSDFKVVKETLPDTLKDREILIEAEYYSVDPYMRGTMFNSPDSTMPGSQVARVIQSRHPDYPVGTKVIAFVGWRDRTIYNPDLVKKMTFFHKLPDLKGLPDSYALGVLGMPGNTAYFGVEKILKIKEGGTLVVNSAAGAVGSIACQIGKLKGCKVLAFTGSFEKTLWLKRIGAGYIFDYNIVDIDETLKEYAPEGVDYYFDNVGGDFSCQVMKHMKPHGKIALCGAISCYNNVDPDTKCVTIPFDYNTFIYKHITMEGFRVTEYESEWLDGITNIRDLILEGKVSAEETISKGFESMPEAFINLFKGGNIGKQVVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIS9</accession>
    <name>A0A1D2NIS9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Monocarboxylate transporter 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIS9"/>
    <dbReference type="STRING" id="48709.A0A1D2NIS9"/>
    <dbReference type="OMA" id="CYSATWS"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008028">
        <property type="term" value="F:monocarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF238">
        <property type="entry name" value="SD10469P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="3">
        <location>
            <begin position="86"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="525" mass="57399" checksum="F85DF6E4F1C7D9C8" modified="2016-11-30" version="1">MANQYQNPRASSYIPTDDIPTVHYRRSSRRFSEIKESNNEEHKSSQNLLESLRQIAQKEEENADEPDFIIKEEYYSPEGPWGWLIVFAAFWTNFIVDGISLCYGVMTENLTEQTNQTSDDYGSNSTTVTSSAGSGTITLTQYNTVGSVLLGVTLMTGPFASIIAEKFGFRKTAIMGSVLATTGILSSWAFSPYEPNFWAFLFGFGILTGLGFGIMFTLSIVIVGLYFKKNREFATGITVAGTGVGTLTMGPVINEILKAYSWQHAILFQAGLAFISILCALVYKPVRKSHDAESQNMPVVQQLKELLTSPSYLVVSFAGSLIMMGYFAPFGFLVDSAADVLGKDRKDDAVFLLTILGIANACGRVFFGILANKIGHALLISNMALTVGGLVTSLYPFAQTHVGLILCAITFGLYSAVFASMRSIVIINIIGEKKFNVGFGLSLIFMGVATFFSNSSAGFLKEKTGNYDMSFYVAGGFLMLSAFICYPLSCIIKCEESKKEKVSASEDINNLSSPRKSLFDVQVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJP2</accession>
    <name>A0A1D2NJP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTP-binding protein yptV4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJP2"/>
    <dbReference type="STRING" id="48709.A0A1D2NJP2"/>
    <dbReference type="OMA" id="SDHTQEN"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="223" mass="25418" checksum="0E838893E961E1CC" modified="2016-11-30" version="1">MGTMKAGVEEYSISFMMQKNMTFKYVVVGDSGVGKSCLIDQFTQTQKEFQEVHLTTIGVNLAEVTRSLRINGCEIMIQVWDTGGMEVYRSLTTAYYRNTAITLLVYDVTRRKTFEGLVDWLSEIKTSSNNPHMIVLVVGNKVDLVKDRQVTRQEGQQFASQNKLFFMETSAKIRDTVEKVFFLTARVYYEKIDMGDIDIHNRPALHGIKLGGEEEQSELISVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJX6</accession>
    <name>A0A1D2NJX6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein Wnt</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01415</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Ligand for members of the frizzled family of seven transmembrane receptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
            <location evidence="1 9">Extracellular space</location>
            <location evidence="1 9">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Wnt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJX6"/>
    <dbReference type="STRING" id="48709.A0A1D2NJX6"/>
    <dbReference type="OMA" id="NCTIHDQ"/>
    <dbReference type="OrthoDB" id="5945655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005109">
        <property type="term" value="F:frizzled binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060560">
        <property type="term" value="P:developmental growth involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007517">
        <property type="term" value="P:muscle organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2460.20:FF:000001">
        <property type="entry name" value="Wnt homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005817">
        <property type="entry name" value="Wnt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043158">
        <property type="entry name" value="Wnt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018161">
        <property type="entry name" value="Wnt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027:SF70">
        <property type="entry name" value="PROTEIN WNT-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027">
        <property type="entry name" value="WNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00110">
        <property type="entry name" value="wnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01349">
        <property type="entry name" value="WNTPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00097">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00246">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0879">Wnt signaling pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="28847" checksum="8382F2AC6CD5068B" modified="2016-11-30" version="1">MLMIQPSLRGSRETAFIYAVTSAGVVHAITQACSSGALNECSCDLSKQGRTTPEGWKWGGCSDNLKFGVQFSRKFVDAPEKSKQWESKNVRSLMNLHNNEAGRQAVSHLMRMQCRCHGVSGSCELKTCWKNVPTFSQVGDYLKKKYQKSVQVPVKQQKRLRRKSGRKFPVGKQELVHIRKSPDYCESDTEKGILGTTGRLCNKTSDGPDRCSILCCGRGFNTKVVKKVERCQCKFIWCCYVKCKPCITRTDIHTCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKE8</accession>
    <name>A0A1D2NKE8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01123</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKE8"/>
    <dbReference type="STRING" id="48709.A0A1D2NKE8"/>
    <dbReference type="OMA" id="HEFCARD"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="296" mass="35095" checksum="8ABECBD5713E1024" modified="2016-11-30" version="1">MDGRSYFDVPVPHKDKMFENATALSQWSHVPWEYENPPVFTSSWWEKVDDPGWKTYMRLHKNIPFYAAIVYLVVIFGLKAYLKNRPAFELRKPLVVWNWTLGIFSMIGFYRMSQELVHVLSLPNGFHKSVCVREGLNEPLAFWAVLFALSKFVELGDTLFIVLRKQPLLFIQWYHHCITMCFVWHIYPYSEPIQRYYGVMNFFVHSIMYPYFALRAMKIRVPRRLAMALTSLQLVQMVIGVLVNMYSIYVLSVRHEFCARDSYTIKWSIGVYSSFVLLFADFLINRYFPKNKPKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKV7</accession>
    <name>A0A1D2NKV7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ell-associated factor Eaf</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_00734</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKV7"/>
    <dbReference type="STRING" id="48709.A0A1D2NKV7"/>
    <dbReference type="OMA" id="VATIWRM"/>
    <dbReference type="OrthoDB" id="125903at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032783">
        <property type="term" value="C:super elongation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003711">
        <property type="term" value="F:transcription elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027093">
        <property type="entry name" value="EAF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15970">
        <property type="entry name" value="ELL-ASSOCIATED FACTOR EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15970:SF2">
        <property type="entry name" value="ELL-ASSOCIATED FACTOR EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="12">
        <location>
            <begin position="22"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="121"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN05918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="358" mass="39973" checksum="8952681530CC7B29" modified="2016-11-30" version="1">MYNTMNGVNVADKLKLDPEVRELKFGSSFTSGGRNQQQGSFHSVRYDFKPASVDTSKMATLDVGPNGQVTISMPNVDGNGTTVFKGARKPYAKECVLIIDHETGEVVLEKLTHNIQVKRTREEGGCKKGGSSSLSMPVVPPPPAVEAKKPPHPSSFKMDPKITNNRERDDSKKPLLSVPSTSQMQHQQPNANKRGPNNSPKPPPPQQQQRQSPNNRPSPGHSVSPPLALSPPSPHPAPAYDSHRSNLSKQSQSQQNSILSLTNFEDLLSMAPPPPQAKAKVDKRYHRRHHHKRKSFRIFPQQCTSQRWLALLPQKVTMYLHYRNLLVGRTAVVVLVVTKMMIVATIWRMCLIRCRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLU1</accession>
    <name>A0A1D2NLU1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-crystallin A chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_00511</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLU1"/>
    <dbReference type="STRING" id="48709.A0A1D2NLU1"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF13">
        <property type="entry name" value="HEAT SHOCK PROTEIN 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00299">
        <property type="entry name" value="ACRYSTALLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="83"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="195"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN06240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="236" mass="26923" checksum="C27C175F4B6C4704" modified="2016-11-30" version="1">MSVPVRRQMRDPYWFDDYMLDHHQPHPRRSFDQDFGTELEPDQFEQDEFLLPPPPSWFRQAMLSHFNNRSSMFNNRLGRLRRSRSTSGGGSSEVYCGRGKMQVTLDVTHFAPEDLNVKLADNYLVIEGKHDEKQEGHGFISRHFVRRYEVPASSPDFEVKPEDVNCTLNSSGILIVEIQLEPPVEEVKGSEKVIPINMTSTSSSSSSKHYKHGHSVRVRATEDSTVAESVDDGNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMV0</accession>
    <name>A0A1D2NMV0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dorsal-ventral patterning protein tolloid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_00314</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMV0"/>
    <dbReference type="STRING" id="48709.A0A1D2NMV0"/>
    <dbReference type="OMA" id="KHEEDCA"/>
    <dbReference type="OrthoDB" id="6155811at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000055">
        <property type="entry name" value="Dorsal-ventral patterning protein tolloid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF1">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905761" evidence="4">
        <location>
            <begin position="25"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="865"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="192"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="339"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN06415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="902" mass="102180" checksum="08793B36BC747964" modified="2016-11-30" version="1">MSANCVACTFIVVVLGTFLQPAVSQRGVSSVISNAQDQCNKTVGIYEEVTSPQVTPENHGKTLLCHYRFRPFRTNLRDWVLRIRFTKFKVGRLVNDSYCENGYVQIVDGNGKSKLSNGREPGKFCGEIEQPQTFISETSVVKIVFYVENFTEQTYFRFDSRAEQQYEVYLRYGQHPELYPNRRGEVVPNTYCERVFRDCRMQTCYVQSPAYPGIYPRNLHCKYYLNTRLPSIKLHIENEEFNVDGQRCENLMLCPMRAIGSECPNDYIKIYDGKDEKSPVIGTFCGMGKFPYSIVGSGSDLFVEFVTSPAGPLLNTGFHFNVAHWPGHVDTSGKKNGTCDWIFTSQALLDSGDKQGLFWSEGHFYPPSTSCNYLILGKPEEIVRLYFPSFRISRIDAPIRKWDGECGESLTIYDAAWADDSKIIKTFCDTFSRPSEKQEFISTSNALFVRFESKTGSYSGSSLYYWAHYDFFNNSHFGDSVGGTLCDEVFTSWRTFEGRFTSPLNTLIYQSGGQPVVCRYRFITARRLFARVVLRIENVNFKYNQDSCVNCWENRVDKVILMDKHRNASRICLCKENQGQYSYPVTLTSQGEEAEVTLKIDPRHALNNYFKINVPIFEGSYRFIHGPLCGPTELGPSADGKLRFPFYFNPSLRDQPVSCLWELKVHPDKDLWIHLDKLVFAISSKSCQDAKLEFYLPSMPTTSMTPGVYYNPSLGISPYHSYAPPKQQHQPLLTLCGDSNVGDRKTEITSELPILSAQKIQQGGPLTIRLEASAASKLNFIISWTELYQLPKNPDGSLMTSKLEQKGDDCGFICPGPEGVCIAQELVCNGVQNCPSNVTGAHDESESKCKSTDNQFIVFNVQLNITWVTASVVGGSLALLFCFCCVICCRCCRRKEPDDPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN43</accession>
    <name>A0A1D2NN43_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_00036</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NN43"/>
    <dbReference type="OMA" id="MLTCNTE"/>
    <dbReference type="OrthoDB" id="447516at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052082">
        <property type="entry name" value="Myelin_sheath_structural"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23348:SF16">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23348">
        <property type="entry name" value="PERIAXIN/AHNAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="133"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="326"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="496"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="618"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="908"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1007"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1615"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1702"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="561"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="630"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="706"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="817"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="854"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1043"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1077"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1117"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1169"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1274"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1307"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1321"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1374"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1454"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1474"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1502"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1615"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1634"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1720"/>
            <end position="1731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN06672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1758" mass="189011" checksum="951B07081BFE32EE" modified="2016-11-30" version="1">MSSVGSLVGAIIGTFFATLVLLAVCYLVWEWERKRRTKRSGLHNLVIVEDGGGTGGGGDGKAYSYDNPGFIDESSGAKKSQQGGGLDAKFNGTGKPASQQNGSKKAPWGPLSFLFKSRTALDDSVVEEPQRYNVALKGHDFTGLGFNICGNMRDGIFVKDIMQRGPAAETKQILLGDQITGMTVSFRQMVLEDAITLLSYASPYEVNLEMLRLSEKSLPHKGIFMSSPAHPSGSSGQSNTLERVCHPFFKSQSIDDLRKVGKEHLDLQVDRKKKQANGVHAKTSGTGGTIEIPTVVVVGNNENRSSSSSSKATSAVKMPKLPKMNFSFGSSSSSTPSPKASKAPEAHQKSSSSSSSAQIQIPMPDEIDGPKGPIVSVTKPEIVPRTKVKTSLVQKSNPDDMELVEAISPAIEKMTAEFEKSKKDLKGSMQINEPSTSSTTAVLDIQPVEINMTGQPSVQVETNDANISTKLPDAKMELPSAEVDVRAPSMVMMPSVTIFGSKDKDSKKKEKSEKSSKLKSPALDIDLTPPDLSLKGGIEMGESSGDKEDSAAIKKPQRGQKTKDKADKSKEKEGKASKAAGKEPKEKDSSEHQQGESSTSGEKSKFFKFGIPVLPEISWNFGVGGSKSSAGDDKDKDKEKGKESKEKEKATKEKGSQGGSDKSESDKKESEPSGVTLEASLPKVEVSKPAVEVKSSEFSLNLPSFELKKDDKKEKEPKEKSSKDKEPKEKSTKEKESKEKPAKESKEKSPKSKDKGKEKEEKQSKEAKQTDQPESEDQQKDVAPQKEKSGSSGFIAAQPGAEPIVEASPDAAATAVKEGETKTKAEKSSESTPSKSKKKEKSEKKNSSRPTSPDGHRTTDDEADKSMDVVDSVPGEKSSRKGSGFHMPHIGIKLPKFGHSKQTYSFENVGDNKDLKHSHGPTAESLLEASPAMKIETTANTAEFRKMTPTPDEIQTPEVAVKVEQPQLEMPTVSVAKKGKDEVDSGDVRVEVEAPKITLPSVSLQMPTAEVKVETEQKEGSAMVFSVPEETISVEAATTSKSTPDEESSKKEQEMKDKESPKEKESKPSFVSKGLKGLRDLKDKVAHKLSHDHTQHDTTTSEDEAEPGDVKVSAAVTKEKVKKEKKSKESREKSKEEKAREKEEKAKEKERIKAEKKLKKAELKKKLSSAHSSSSSSSSSSSDESDADDGTGGKVEKKEKKKSKTKDSKSAKEKKKKDKKEKLDKKLSGIEIQAEIPGVELQNPEITASSAIEKQLSGHEAKLIPAKPPVVPRKSRDSLKDESGKGAAGDEMGSSKGKLKKSKSKGDTSTSSSSSSSESDSENKKDDKEGKPKKPKRTPKRKAPEVPSVSTTATSIDVPDLVKITTSAEVISPPREDKKSEEMRESTPSKTPESGRRSASYGDLSSLHTKPMGEGPLERAMSMDMAGDKENSNEPGAMPVGSSQEDLSVMPDSKTITHLSRNQQHHQGLRDSIASKSSTSSCETLKASPTSVVQVHPKEQQPQELVQVTSSQVSQNAPTTTTISVSSEQDPHSSTIQKMMNETLSVMNNIVHEMDSPSLVKSAMSSGQSTTTIVKTAEPQVTISTSGTSLVEKSEAEKVAQQTVDEIMEKARASLSSDMSVSVTSKEHDGPKVSVSTGDNNDNNTMISDLAHSLSADMEGGADSFSIASVKIQGMDGDSDEPVSVRNITVTNIKNVPKQAIDVDNSGASSNEPHDQVEVSSSGGTIISGSSDPSKAAPLLREDSKARLLQTVADAKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M158</accession>
    <name>A0A1D2M158_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007585">
        <property type="protein sequence ID" value="ODM86700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M158"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903367" evidence="1">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="59" mass="6626" checksum="975C1393E262E93D" modified="2016-11-30" version="1">MKFLSIVVLIVATGLISIPEKSQVLASVDECYCLDTKPDEKMWPSIMLALAKHPRDYNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1F5</accession>
    <name>A0A1D2M1F5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Longitudinals lacking protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_19900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007270">
        <property type="protein sequence ID" value="ODM86782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1F5"/>
    <dbReference type="OMA" id="AVPPCAT"/>
    <dbReference type="OrthoDB" id="8291405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF93">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 14-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="32"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM86782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="28516" checksum="2C1829709F21847A" modified="2016-11-30" version="1">MESKNQYKLRRKDHSNSVLQAIARQLTEERFTDITLSCHGQIIKCHQMILSACSSYFNQIILDMATPNLVICLDEIKFWQLEALVAYMYTGQITMGYGKLKQFINAVAKFKIRGLVKEVKAHLQNLNNRKKVKTMKRGNAVGPGSSQAPNSTGTTPNTQEDPAMRKLVQGKRKRTSEPPGLLKIGSNDNAVARAGVELNAVKKVAKPARNPINQMAHQPHCFLFQKRAQKLSQVELATCQLLQNLVQKRQYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1P1</accession>
    <name>A0A1D2M1P1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006859">
        <property type="protein sequence ID" value="ODM86889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1P1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="13355" checksum="6D8C221594461F8A" modified="2016-11-30" version="1" fragment="single">MTTVQLMGPDCVLLGQALTCWRGSVYGAVMTFRGKQVCGMSFKNLGITNEQIKILPIFMIGASLIDESHVLTAAHCFKAISIALSPDFNWDHDISDPMDVQHQERNVSKSCTIKNFLLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1S6</accession>
    <name>A0A1D2M1S6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hepatocyte growth factor receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006779">
        <property type="protein sequence ID" value="ODM86915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1S6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10106" checksum="4F8B337F4DD8DCFA" modified="2016-11-30" version="1">MNFFGPVHIHTFNNNMYTNDVGAQVRSSSRLTQAPPLDNALISQSAQPTPAIPLLQLKHRQLHGSTQEKVTKSVPAQRAPLATENGVPAHLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1V7</accession>
    <name>A0A1D2M1V7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein sleepless</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006675">
        <property type="protein sequence ID" value="ODM86949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1V7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903381" description="Protein sleepless" evidence="1">
        <location>
            <begin position="20"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="24055" checksum="75D338E305A33813" modified="2016-11-30" version="1">MKVLLILGALCLLMAYSEGLKCYNCLYLSDKLPNGLNATMKSESSCQAGKKPKKDFIVDCSRLLIPKSGEKAIGTTNILTSFLGENHPLVAMPYQNNGTNLTVTYTCGKLSYDGTFLPYYGGKKMKAMIRSCIPKLSYGNSTFQQQCQNGKMDKLNINDLDLRALVFNGGLGVAMNHSQTDVSICTCTKDDCNGAMLNNQISIFVIIASLMTVLLLRNKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2I0</accession>
    <name>A0A1D2M2I0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mast/stem cell growth factor receptor kita</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19529</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006034">
        <property type="protein sequence ID" value="ODM87154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2I0"/>
    <dbReference type="STRING" id="48709.A0A1D2M2I0"/>
    <dbReference type="OrthoDB" id="7789554at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF600">
        <property type="entry name" value="PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="361"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="531" mass="60443" checksum="969EEEA996C06F13" modified="2016-11-30" version="1">MWQFDDRARSVGLCDETCIPNEDTSDSWNGTNPINVTFFQKEQFGGQSFSVQVEECTQILKWPYLDALSIRIPPEACVLIFLKHSRAARDVSDCSTQDWDNVLEIRDGVPALNDLRRHILNTEFLGYISPCYCKLNPNPNPPPFTYIRLFSWPNFEGNSTQIFLNYSGCKDFAKDAVLEKWEGVAESISVSYGGCVKVFKERNCEDMSGGKELITPFATLDDVELFAEIRSLKLCRAEHNPEEERIPISDTKIPNTRVWIYLLTIGGISILTGTSLVIAALYLQRRTKQIKKATSKLLSNTEINEFLYGHPLDCKDEENKNIRNFIDQESQTDSLQFSYESHVNNKPYDYQLEIKRDQLHFDNKHPIGSGQFGLVYKGVMTVEDTAVDVAIKTSKPLSGAESLRTLMREVKVMMYAGHHPTIVNLMGCCTANLQEGYLFIVMEYCNNGSLGNYLMTNQHNFVNSLKTETIFSSVTFVKNDHITTDYVKQLTFPQSSPCNLEEINRFDSHQLIVWSRNIADGMDYLANKKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3K8</accession>
    <name>A0A1D2M3K8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amine oxidase</fullName>
            <ecNumber evidence="3">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19126</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="3">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01005073">
        <property type="protein sequence ID" value="ODM87557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3K8"/>
    <dbReference type="STRING" id="48709.A0A1D2M3K8"/>
    <dbReference type="OrthoDB" id="10010411at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="4">
        <location>
            <begin position="5"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="7171" checksum="707A48AB150119D9" modified="2016-11-30" version="1">MRTLNTDVVLWHNFGLSHVPRVEDFPVMPVEHVSIMLKPYNFFKENPALDVPPPRRSRTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3M8</accession>
    <name>A0A1D2M3M8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005023">
        <property type="protein sequence ID" value="ODM87578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3M8"/>
    <dbReference type="STRING" id="48709.A0A1D2M3M8"/>
    <dbReference type="OMA" id="VENEQFR"/>
    <dbReference type="OrthoDB" id="6620774at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47501">
        <property type="entry name" value="TRANSPOSASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="24958" checksum="44B5237758C8A13A" modified="2016-11-30" version="1">MLGENEAEASQSSSEVATHKPGGVQTTVKLPGIIDNRRYSLLSTGKTTNGVTSISANCLLCKGGKTIHGDTKSSGNFIKHLRAVHPTQHDEYKKRKSQPPTDETQPSMKKLCSVLSVTSGKTKRADHLVMMYIVNDMRPLSTVSSPAFRCMIRGLCQSPDMQIMCRKTLQIQINTYYDEIVSALSLKLKSLDYLCLTADCWSSHARAFLGVTCHWIRTFPENQEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3R6</accession>
    <name>A0A1D2M3R6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004959">
        <property type="protein sequence ID" value="ODM87618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3R6"/>
    <dbReference type="STRING" id="48709.A0A1D2M3R6"/>
    <dbReference type="OrthoDB" id="7775224at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="2">
        <location>
            <begin position="7"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="14688" checksum="EDEFFE520C2BB815" modified="2016-11-30" version="1">MTRTRNHTTGTIAGGKGIGVAPGAKWAACRGCASSACWQSDLLACGDFFACPTRADGSSPDCSKAPNVVSNSWGGGRGNTWYNDVIEGWHAAKIIPLFSNGNSGPSCNTANSPADQNAKEFLLGQPIKPGVHWKDLRRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4P4</accession>
    <name>A0A1D2M4P4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004486">
        <property type="protein sequence ID" value="ODM87881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4P4"/>
    <dbReference type="STRING" id="48709.A0A1D2M4P4"/>
    <dbReference type="OMA" id="THYLSNC"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18088" checksum="F030F619507FF09A" modified="2016-11-30" version="1">MMPTDNYGGECGTISPKTGFLNNCGYNGAFEALNYIHGGELIRPTSSTKAVGDLRLFDQSEFFNNKPKLASMDESGFVYIPTACKNGTQCALHVAFHGCTQNRETYADMYPMKGGYLEVAELNNIIILFPQIAKTASNPHACWDYWGYLNIMFVCKMTCCTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5M9</accession>
    <name>A0A1D2M5M9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003840">
        <property type="protein sequence ID" value="ODM88278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5M9"/>
    <dbReference type="OrthoDB" id="6602143at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18292" checksum="0B6F6E762531A9AB" modified="2016-11-30" version="1">MSKKLKQNPSMSERIRKGEVRYHSCNGILVERWKDKKEVRMISTGMPPEMKRTVNKAGTEKEKPATILQTSGATIISTVGEHSTTKGRKATVSLESSKRLTERHFPVQVPVTGKTKYPTKECAVCRKKNGKGKTGDLRHAICAQNVMWACVLMAVFARIIRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5P7</accession>
    <name>A0A1D2M5P7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003786">
        <property type="protein sequence ID" value="ODM88310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5P7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="79" mass="8685" checksum="58AF6101D77CF282" modified="2016-11-30" version="1">MECKRGTRPPVISQEEYMQTEIPTEITSTSIASTPKPGFLSECGQTIVANSGTIEYKLYEKLRCVSSVCLSSGLEIIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6A7</accession>
    <name>A0A1D2M6A7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine protease AprX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_18168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003486">
        <property type="protein sequence ID" value="ODM88515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6A7"/>
    <dbReference type="STRING" id="48709.A0A1D2M6A7"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="25"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM88515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="14553" checksum="194CAD36D728889D" modified="2016-11-30" version="1">MDLTQTATKPQPRQQLLGGGQGATFYNDVIKAWRAANIVPIFAQGNAGPSCATANSPGDSSSVIGVGATTSADGIASFSSLGPAVGGAVKPDVSAPGQNVRSAWSTSDESYSTISGTSMAAPHVAGCSTFALKRPSLSYDQVKAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7J2</accession>
    <name>A0A1D2M7J2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">Ocin01_17754</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003053">
        <property type="protein sequence ID" value="ODM88929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7J2"/>
    <dbReference type="STRING" id="48709.A0A1D2M7J2"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF39">
        <property type="entry name" value="INNEXIN INX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="383" mass="44897" checksum="8727554395167795" modified="2016-11-30" version="1">MQNYSPQLWLLKATKNTQTPNILCTIIAEQVEESPLTNKMLRLWAYYTRHQEIIIDNPIFRIHSSFTTVLLLTFSIIITWTDLVGRPIQCSVTGVPAYMVTSYCWIETTFLMPGKCISETKETTTMTKLPKSTTNLSVGLLCTVFFKRYSVTSRNGCVREVGGWTDDPHRLWTQHPTSSRDRKELEKRDNEQLLVNIILQMVFMNWFFKGDFLLYGLKVLTFMIRPRRKIRPHDLRFPTRYQMHLRKFGPSGSIEKHDAFCILPQKNFSEKIHIFIWFWFIILAVLIAALGLPHLHAKAPAFLLYSRTRMVPKEVVDSICRRVSVGDWWILYMLGRNVDPQIYKEVITDFAEKEHTVKYIIIRIPPQCCAPTNWFLKLFYAIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7Q3</accession>
    <name>A0A1D2M7Q3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003036">
        <property type="protein sequence ID" value="ODM88952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7Q3"/>
    <dbReference type="STRING" id="48709.A0A1D2M7Q3"/>
    <dbReference type="OMA" id="HMRENNA"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="88"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="261" mass="30430" checksum="81BFA4F2C1B92030" modified="2016-11-30" version="1">MGNPDVEHDAETGLMEMRAFYKEFRNKGDGSQPVRQFLEEAFQDETLLLRYLKGRKFRSQYAWDTLRRYAEVRFDSYPETFTDPISKSALHMRENNAFGVLKHRDSEGRRIVYFNTNEWDIDKVTIKEAMAASLPLIENLLLDKDCLDNGLIFVQECSAMSMKHAGQYTLPAMLRVINLYWFAYPIKVKGVYFVNFPFLLAFLYRIVKPFLPKKLKERLFLTPPSRKFDDLTAQISPTILPKILGGDLELEEAVDPNFLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8D3</accession>
    <name>A0A1D2M8D3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_17488</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002823">
        <property type="protein sequence ID" value="ODM89192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8D3"/>
    <dbReference type="STRING" id="48709.A0A1D2M8D3"/>
    <dbReference type="OMA" id="LEWAENY"/>
    <dbReference type="OrthoDB" id="10262308at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000005">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000002">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="125"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="29247" checksum="0EE7556BB82B4EF3" modified="2016-11-30" version="1">MPKSKRDKKVSLTKTAKHGMEWKKKLVKDVQEAAQEYNSIYVFRVNNMRISGLNELRKKFRDSKMFLGKNKVVALALGKDAQSEMLQDVHKISERLQGECGLLFTSRQESEVMEAFESFCELDYARGGAHATKTVELEEGPLEQFAHSLEPHLRSLGLPTSLKKGVVTLIKDYKVCKKGQVLTPEQARILKLLDIKMAEFRVVVDSVWTKPDDFKVLLKLDSSMVEDEEEVDEDQEETIVEDEEMDDDDNDGESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8J4</accession>
    <name>A0A1D2M8J4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">F-box only protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002740">
        <property type="protein sequence ID" value="ODM89298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8J4"/>
    <dbReference type="STRING" id="48709.A0A1D2M8J4"/>
    <dbReference type="OMA" id="HIFFQHG"/>
    <dbReference type="OrthoDB" id="1107553at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000012">
        <property type="entry name" value="F-box only protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007397">
        <property type="entry name" value="F-box-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039752">
        <property type="entry name" value="F-box_only"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12125:SF5">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12125">
        <property type="entry name" value="F-BOX ONLY PROTEIN 6-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04300">
        <property type="entry name" value="FBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01198">
        <property type="entry name" value="FBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51114">
        <property type="entry name" value="FBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="FBA" evidence="3">
        <location>
            <begin position="78"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM89298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="39651" checksum="BDD6D528C52018E8" modified="2016-11-30" version="1">MEHLDVSLAEGLPDTVLEVILSKVPEEDILNCGLVCRTWKDLITRKSLWKIRFEDKGIPWDEVPKHVRDKAAGWMILFAHLRHRILSKNFIRNPSGHSQFDGWTIFANDGHEWLVEQVPEGCNPLPAPLPTSPFFGRNDEYSCFVTSFEWCSKYYFIDLWRDGLTPGLLELMLPFKIKCSQLYTVRFDCGGVFNWELRLLNSQEQIITKYKPPTFELPATRDWKTAEYSFQFGSEDEELLQDLRYIVFIHEGKDTQWWAGHFGMKFARSCVTFECLENEPEESDRVERLSEFGEAGGRNTLVERRRSYNNMYYHPEYEYEDDDEPGHDPYAGDEQDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9D9</accession>
    <name>A0A1D2M9D9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_17078</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002511">
        <property type="protein sequence ID" value="ODM89603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9D9"/>
    <dbReference type="STRING" id="48709.A0A1D2M9D9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF2">
        <property type="entry name" value="FMRFAMIDE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="633"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="678"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="712"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="133"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="465"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="775" mass="89079" checksum="5B68A781463BA39A" modified="2016-11-30" version="1">MVGIWMRGLQDTLLVVKSVAPFPILSTRGKRNRDCEPYNGMDYKRGYKYAKMCSLSRFTVLAFGSTLSTWELYTFNGPGPETDKVYRRRLVYYRPQALEHGSYIFSSNNTTGLSISIFLSVLTFIVSGFGSVSNLLTIFVLNKSIPIGVSVRESQIALAFAEFLLCAFTGINTIFVILILGNWTRGIAAFFILNFSHRIFLVGRTVTFYQSILISIERYLMVAFPLKSKIWLQRSRRRSIAAFILLIVFSILLNLPWLLKSFVEENEKVNWKTNSTLANFPYLVKRHEYFSTIWIRGSQEIMLGLNSVVPFPILLILKGLLYKAIARASDQRTVLTNGLKKDINSAKMFSVVVIILLSCNIMPIAVYMTSRARMEIYRELILLQDLSVLTGAASNFIVYYAYGKAFQREFWNDHQFFSPSENLTFTYFCKVHGSYLSESSSYDGHLMCVIISALTIFVSLFGVVTNILNVFLLRKSISRGLSFRESLIILAAIEFVFCFFAGTNAFLTICILNNWDRSYSALMLFHISNHVFIVGRTVSFYHSIQVAIERYLMVVAPIQSKIWLYRSRKRSAVGFVVIFILAICMNLPWLTKIYIGQNEVFHWKTNSSLGSYPYLVKRDEYYSKMWSRTFQDVLLVLKSIAPFPLLLILNGLLYISISRWNKRRAVLTGGHQRNIKAAKMFSVVVFILLTCNFMPCVTYITNRAIKELYRELILLQTLSVVTGSAVNFLVYYYFGLSFRREFWEIIGNIKICFIGWNLSKEKRPSHDTNMTDTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA30</accession>
    <name>A0A1D2MA30_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002350">
        <property type="protein sequence ID" value="ODM89801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA30"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="17864" checksum="6D1B0B20BA55CACD" modified="2016-11-30" version="1" fragment="single">HRVEFVGLVDAFEAASNGITKSIIFFRRLVDRKVQISNRALNVMVTFKDWHDVQSDAEKVYSLLKEEMRGFLDFERPDLLFKEGMNLEKMREHVQADERFAHLDQIQVDKIEKEWKNLNLIPQLKDCIEEMEVLAAEVPKDAKWTSLWTGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAB7</accession>
    <name>A0A1D2MAB7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16746</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002283">
        <property type="protein sequence ID" value="ODM89936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAB7"/>
    <dbReference type="STRING" id="48709.A0A1D2MAB7"/>
    <dbReference type="OMA" id="CEHIHYH"/>
    <dbReference type="OrthoDB" id="8895262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000690">
        <property type="entry name" value="Zinc finger protein 354C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000643">
        <property type="entry name" value="Zinc finger protein 668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376:SF216">
        <property type="entry name" value="ZINC FINGER PROTEIN 420-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="389"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="449"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="506"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM89936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="573" mass="67556" checksum="25535A0F610562FA" modified="2016-11-30" version="1" fragment="single">FLTNWGLKEHIQLHIREKPSSCSICEKSYRNNTELRKHIHVAHTNSKPHKCEICSKKFSLSASLQLHVRRHLGEKTYKCENCEKQFVTSSELNLHERTHSVEKTYSCLICNKYFTVNSALYEHFRAHVREKPNICNICGKEYVTGKSLKIHKQAHSGEKPFECVFCGENFLTMKARTNNSLEQHLRYHIREDSISCKSCPESFFRSWSELKKHQQNFSCYLCHKQYHQLGHLKRHFQTIHSRRSFHYCFCGQHFSSREKLKTHRTSHYAQPPFKCETCPKVYPTYQGLWSHKKTHSNVKRYKCLVCYKRFDVRAYFNQHVLAHTGEKPYKCSTCDKRFLSKSNMNQHHRNVHENLARSYNYNCIFCNRSFAQLSTLKHHILVHVREKPVDCETCSMSFINESSARSHSKIHLMKSTASYKYACIMCDALFPSITLLQTHIQNHTREKPFSCETCERVFSTSSTYYRHVKVTHNNSGRFSCEICGKKVTSSTSLRHHISRHLGEKSLQCNLCDKRFVSSQELKIHVKRHKGENELRMYFLWEVVLQHGTLCEHIHYHTLEKHTLAANAIENLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBG8</accession>
    <name>A0A1D2MBG8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002093">
        <property type="protein sequence ID" value="ODM90234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBG8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="19383" checksum="60F3465BEE8DDDC2" modified="2016-11-30" version="1">MPRHPGVVPCVLLKMESVQLVQTRKCWRRNGYKYSPSFSTSFFLLTTFIICLCGFAEAEKFTSEVSNVPKQKTVLVEQPTDSLQNALSLATSSLSKSITMDTLNLLTRIKNTVAEWGRESATSRTFFIFPFIATMAPMFLAQMSGVAISIIPVTGLLLIPALLLPLGLTLAVYWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCQ7</accession>
    <name>A0A1D2MCQ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001801">
        <property type="protein sequence ID" value="ODM90765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCQ7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="200" mass="22389" checksum="A510B697C4442F2A" modified="2016-11-30" version="1">MENDSWETNWSVCSSNGMGYTCRMDVSVKGLWIFFVSGWSNESPGLAEFRFQERVGDYQPLAPDVAGKVFCLKQTGEPSDYKTPALTLFYQLELITDSLTRHFDTTGSPDSCSNSLIDTVRSLVINGVERWEIFRRDATSVCIQVENTTSFIPGIVRDTRTLGLDHDRGNVCALVRGCSKPSNEVIRIPNSETSSVLRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD52</accession>
    <name>A0A1D2MD52_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001747">
        <property type="protein sequence ID" value="ODM90910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD52"/>
    <dbReference type="STRING" id="48709.A0A1D2MD52"/>
    <dbReference type="OMA" id="YHECIAR"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="66"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="523"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="600" mass="65595" checksum="34E274A83B5C6682" modified="2016-11-30" version="1">MAVVDAVNTILRALPARWPIPLPVATVAATLLTLAINSWVTYDMTQDATSNSEILSLDSKCQFTTFDYIIVGGGGAGMVVATRIANASSSDRILLLEAGGEPSVLNDIPGLDVYLQNQPGNTWFYNSTPQANACQNCDGKKVMTTRGKMLGGSTGTNFMMYVRGNKEDFNRWSTEDLGGDPQWNYENLLPYFKKSEDYNGIWTSDPDASKYHGKGGLRNVGTNDYMPGADELLAAAREKGYTIGDYNGANQEVFSKIDLTTQNGWRENTYRAYYKDTGKPSNLCIKKYAQVIQIKFKTVSGKPKAVGVIYKRQGLTRTATARKEIIMSAGTFGSAQVLMLSGVGPADHLESLNIPLVKDLPVGQNLQDHTTTLVGPFLKAPSLNPDRDITAQAAVNYLTTGNGVLASSDSLAGQGFFKSPVAEPDYADLQVVHAALALYPELPHDVNKLFGIRVDILERWFNPYHTLNTDARFGLLVLGRPKSFGNLTLASRNPDDNPIMDPQYLTHPDDLEAMLFGCENLVFKSDDYYRCVIRMFSFTLYHHVGTCALGKVVDSKLKVKGIDGLRVINASVMPRLPNGNTQAATIMIAEKGSDLIIADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDN1</accession>
    <name>A0A1D2MDN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">5-hydroxytryptamine receptor 1D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15597</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001676">
        <property type="protein sequence ID" value="ODM91085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDN1"/>
    <dbReference type="STRING" id="48709.A0A1D2MDN1"/>
    <dbReference type="OMA" id="PIMEFND"/>
    <dbReference type="OrthoDB" id="10042731at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF125">
        <property type="entry name" value="DOPAMINE D2-LIKE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 11" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="227" mass="26144" checksum="218CF69A60F104B3" modified="2016-11-30" version="1" fragment="single">IGLECASTFHLAAIAFDRYRSIVDGITYKRRRTFRSVFVKVASLWVITAWMLMDPIMEFNDKTQWSGLEEGYCRYNTSTKWVIHIVVGMYFIPATLLIVLYTKIFLTIKKMLKRREKMCLPVFSSESPCSSYSGIVQRNSEATFLAERKAARMLGFVIGAYRILVTPVYICHLFSSMVTVPKRLFTLAAILVHTNSGGNPVIYAFCSSEFRKAFADVVLFWRKFDMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME37</accession>
    <name>A0A1D2ME37_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001604">
        <property type="protein sequence ID" value="ODM91287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME37"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18211" checksum="7CACFC0DF18A4463" modified="2016-11-30" version="1">MSQQSHRFPYYTSINHAPAFESAPMFPHRVGATRNLPETGLSPRRFASHRFEQQRVYESPLPAPQNIPNHEFQRQPSGNFCNNFNFYGTINAVHINNGEPTHHHIPTAQGKSVGLNNNSQAGATVPPPDGNEASAPSPAVAPFEQGQVRRKQLELMSDSKYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME95</accession>
    <name>A0A1D2ME95_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001619">
        <property type="protein sequence ID" value="ODM91253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME95"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="16676" checksum="2AD4FE5A24A1518C" modified="2016-11-30" version="1">MPRGKRKKVASPSYERSRSRTSSSDHHHHRKRRRHESPSSSPTTPTDSEVSSQTASKSRSRSKEKERAVSSSDESYPRKKNHKRTWVNISRRVTDDTTIANTIFANKVCRYKMQVMHVTDQARSNDLHLYFKVNWWLTIVYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEP5</accession>
    <name>A0A1D2MEP5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_15351</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; sulfate assimilation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001590">
        <property type="protein sequence ID" value="ODM91331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEP5"/>
    <dbReference type="STRING" id="48709.A0A1D2MEP5"/>
    <dbReference type="OMA" id="IEIYKHH"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="UniPathway" id="UPA00097"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050428">
        <property type="term" value="P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.400.10:FF:000002">
        <property type="entry name" value="ATP sulfurylase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000006">
        <property type="entry name" value="bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003013">
        <property type="entry name" value="PRK03846.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055">
        <property type="entry name" value="BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055:SF1">
        <property type="entry name" value="PAPS SYNTHETASE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="APS kinase" evidence="16">
        <location>
            <begin position="46"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="18">
        <location>
            <begin position="233"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="17">
        <location>
            <begin position="391"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM91331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="636" mass="71362" checksum="C14BB34AD6C6EA7B" modified="2016-11-30" version="1">MNGFLNGLPPAVYRAKMQAATNILEQKHHVSRDSRGQILGHLRGFRGCTVWFTGLSGAGKTSISFELEAFLVGHGIPSYALDGDNVRGGLNKNLGFSKEDREENIRRVAEVAKLFADSGVVALCSFVSPFEKDRDLARKIHEESGLPFLEVFVDTPLDVCEKRDVKGLYKKAREGKIKGFTGIDQAYERPSKPDISVNTVGMGIKDSMMMVIDLLVQKGILPSELRAVDRVPELFTDKTQEQILNAVNESPALEITDLDLQWVQVLSEGWATPIKGFMREEQFLQVIHFNALVKDEFVTMPLVISLPVSTTDKERLEGATQICLHYKSKPIALLKDPEFYAHRKEERCARQWGTTSPKHPYIKMVLESGDWLVGGDLEVFDRIRWNDGLDSYRLTPNEIRKRIEDIQADAVFAFQLRNPIHNGHALLMQDTQKKLEENYGYKKPVLLLHPLGGWTKDDDVPLPTRIEQHLAVLEEGVLDPKRTILAIFPSPMMYAGPTEVQWHARSRLNAGANFYIVGRDPAGLPHPEIPSTDLYDATHGSRVLKMAPGLPGLEIIPFRVAAYDKTVKKMAFFDPKRKEEFEFISGTKMRGLARSGELPPDGFMAPKAWTVLSNYYKGLSSGLNTSNNNHINNAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFZ8</accession>
    <name>A0A1D2MFZ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein NDRG3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NDRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001385">
        <property type="protein sequence ID" value="ODM91893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFZ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MFZ8"/>
    <dbReference type="OMA" id="CNPSESM"/>
    <dbReference type="OrthoDB" id="741027at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000047">
        <property type="entry name" value="protein NDRG3 isoform X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004142">
        <property type="entry name" value="NDRG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11034">
        <property type="entry name" value="N-MYC DOWNSTREAM REGULATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03096">
        <property type="entry name" value="Ndr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="564" mass="61703" checksum="0C27E73F25F2A064" modified="2016-11-30" version="1">MRSMFSGSYSALDNQGGPDTVGHGDVYRATTRPSFDAGIPIARQTDNRFNLAESVKKLFRGAANNMSGNSGGRLRASQSVFVLPSIHENVNLPPMSSNTNASSAVNYDRLLRRDNRARRMPSSQSMEEAALLGCNPSESMDEVELRNIQLSFPPTRSLSRGEGLAVEERVETKFGTVLVAIQGDRSKPAIITYHDLGLNYVSNFQAFFNFVDMRILGQNFCIYHINAPGQEESAPTLPDSFVYPTMDQLAEQVMDVLLHFGLKRVIAFGVGAGANILCRFALSNSQTVDALCVLNCISTQAGWIEWGYQKINTRNLKSKGMTQGVLDYLMWHHFGRVTEERNHDLVYVYRNYFESNVNPQNLGMFIDSYIRRTDLAIERNLDPIRRKDARTLKMPVLNVTGAHSPHVDDTVTFNGRLDPVDSTWMKIQDCGMVLEEQPGKLAEAFRLFLQGQGYVPTLSSKKVSQNRKMSVDSGVSGAGSSAASSSVSLNNGTAKDGMSASSGVVTPKSVDPSSGTLINLASPDTAPATTKSGLEKGIIDIRITENPISESPELSSDLDANPTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHN1</accession>
    <name>A0A1D2MHN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase type-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001233">
        <property type="protein sequence ID" value="ODM92431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHN1"/>
    <dbReference type="STRING" id="48709.A0A1D2MHN1"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004303">
        <property type="term" value="F:estradiol 17-beta-dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008209">
        <property type="term" value="P:androgen metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008210">
        <property type="term" value="P:estrogen metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="153" mass="17324" checksum="9DD95BCE9FE1B9DD" modified="2016-11-30" version="1">MAFVFKEVISDIPTSKGDTVVKELGNDALFCSTDIRQKNVQATLAACKDKFGKLDLVVKCAGVEAAFKVYNFNKTLSYLREDLKRIIDVNFKKIAACRLGLPNEFAHMDEFIVLNPMVNEEAVRVDGILRMQAQSKRSNYIRNYDDDEGGDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHT2</accession>
    <name>A0A1D2MHT2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein HIRA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_14147</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001206">
        <property type="protein sequence ID" value="ODM92536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHT2"/>
    <dbReference type="STRING" id="48709.A0A1D2MHT2"/>
    <dbReference type="OMA" id="WIVENHR"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="8">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="129"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM92536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="503" mass="56125" checksum="DE687FD26FA6B468" modified="2016-11-30" version="1">MRLLKPSWLHHDGNPIFSIDIHPDDTRVVTGGQGNDSVGRVVIWNMQPILSKEEDATVPKLLCQLDHHNACVNCVRWSNSGKSLCSGGDDRVIIVWKLVSRFSGNVSTTAQNSAFGKTNLEQWKPSCMLRSHTGDILDLAWSPGDRYLASASVDNTVIVWDAQKFPQIVTTLKEHNSLVKGVTWDPVGKYLASQSDDKTLKIWRVSDWELEHSVQDPFVECGGTTHVLRLDWSPDGSYLVSAHAMNGGGPTAHILQRTEWKTNKDFVGHRKAVVCVKFNNNILQSDNSRMQHCCVALGSRDRSVSIWSTALKRPLVVIKDLFTNSVMDLSWSSCGTVMMACSWDGSVAVAQFSWKEIGKPLSPEEKANFYHKQYGKSAVSENCDIIQNLEVFLAKSKVVPSSGAVENSRITPEGVVEVIPQPERVVKGPIDKQIETRTADGRRRITPKFLLPPTDGEQAVTTKSTFFNALQQSLTVPPFRTSEFKIPSWIVENHRRSQVEETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIJ1</accession>
    <name>A0A1D2MIJ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001149">
        <property type="protein sequence ID" value="ODM92793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIJ1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10598" checksum="8DF12DBE8930ADE6" modified="2016-11-30" version="1">MPDFTKQNIPTEEEMEVEDSNNQGYHQDAVPSSSRSEALMRFLQPRKARKEDVQMIDVSADDLKSDPTEWLRNITDESAAPAREEKDWVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIM2</accession>
    <name>A0A1D2MIM2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transmembrane protease serine 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001134">
        <property type="protein sequence ID" value="ODM92846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIM2"/>
    <dbReference type="STRING" id="48709.A0A1D2MIM2"/>
    <dbReference type="OMA" id="TLNCRCG"/>
    <dbReference type="OrthoDB" id="7740727at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="571"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="360"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="419"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="810"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="419"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="533"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="816"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="843"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="866" mass="93319" checksum="8C69B297C3F3BAF8" modified="2016-11-30" version="1">MDPTRNRVRVEKNINNFRKYSKFYAGLCLITILTISNVANSITAVGAEEDNFSKTSPVYKASKSCKDGQNCVEDNSPNPMKTPKDQQDSLTTFINWLFGPPASASISKPELGEKTSTVVSSNRRNYSAPSSSVVSKDQLGRPELEESNESIHNESASTRLKRDYKPVKVPYTNDKNKDSVNSSELRRRQLLINPWDQQAMQAMQQQQQQQAAAAAMLQLQQQQQQQQMMLNSNRNRYPGYLDDYDDDDSDEDSDEFEDFSQFGMYNGGPPYVHFQRKMGLGRRSVPEGDKKQKKWNGRRPTQNEGESSGNGRISSNNNRHSLRNGDWFLDDYDLNSAFYDRPQERRHLPDHLLLDEDRKEMDEEHLEGNNGDKAAASDYAEKEKAEADHLKHRGDLDYIYREFKDSLCKGNECLQVRQTSTTMGGSTSGGSTTSGGSTTSGGSTTSGGSTTMGGSTSGSSTMGGSTSGSSTMGGSTSGSSTMGGSTSGSSTSGSSTSGSSTTTGSSTSASSTTGAGGTGSSTTGGTGAGSTTKKPRTTTKKPKTTTKPRPPPPYKATLNCRCGTQSVRGDLVGGGTVIRYNVNPWLVSISSGTKHLCSGSLINDRDVLTSKLCTKNSGGNITVIAGMTSRKPTNYSVTKITTNPKFNLAILRLSKPIKSSHTMRPVCLPIGQRSSGDYSTGTLVTFKKGPPPRNNTLQMVDAEVALMSSNSSSKCNSTAAGSICVGPPGSIKCGGDTGGLLQVYRGGYSYEQIGVVAGTVGCRSSSTPGVYTDIRKRVRWILNNAKGGNFCKNPKISTSDLSSTIRLGDPAYSLNNDDDNVNEVEEESPEDDDNIRLGAVLHEDEEDEDQGAEIFDDGEETRDDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIP4</accession>
    <name>A0A1D2MIP4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein timeless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001138">
        <property type="protein sequence ID" value="ODM92825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIP4"/>
    <dbReference type="STRING" id="48709.A0A1D2MIP4"/>
    <dbReference type="OMA" id="NDFENNT"/>
    <dbReference type="OrthoDB" id="310853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044998">
        <property type="entry name" value="Timeless"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940:SF4">
        <property type="entry name" value="PROTEIN TIMELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940">
        <property type="entry name" value="TIMEOUT/TIMELESS-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26019">
        <property type="entry name" value="HTH_TIMELESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="377" mass="44047" checksum="342077956EE72E50" modified="2016-11-30" version="1" fragment="single">TRAIEQEQEFDFRGFVLKYAMAKVVCNYALLLQDWDTLKPLTLHCIVKMFHRFVFDMGYPALICQASLFLTFKKILEVADLRSDLKEVKTFFLHFWPKFVKLCEDKKMFIEILFWKTAREAQEIQDGYSDLRGPSGGASNKKSNWTSEEENELELLVELYNDAPEEVKKAQKLVDFIMERWTWRPKSKRLFMLKLVEKELVNPETVAKKARPPKTWGDEEIEKLRDLYEEHKDSDDVMGSILENMLIKRSKKSVIDKMIQIQLITDKSAVKKRSKRSKKHFPSRSQVSTRSDSDDENENNGEQERSQQRSERPQSSGESSDSDSESSDSESNDDDENDKENFSRLEISSNRVYDDEKVFDLGRKLMANDMMGSHPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIT4</accession>
    <name>A0A1D2MIT4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ubiquitin carboxyl-terminal hydrolase 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_13763</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001119">
        <property type="protein sequence ID" value="ODM92918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIT4"/>
    <dbReference type="STRING" id="48709.A0A1D2MIT4"/>
    <dbReference type="OMA" id="WHELEEP"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049548">
        <property type="entry name" value="Sina-like_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47022">
        <property type="entry name" value="BTB AND MATH DOMAIN-CONTAINING PROTEIN 36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47022:SF1">
        <property type="entry name" value="BTB AND MATH DOMAIN-CONTAINING PROTEIN 36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21362">
        <property type="entry name" value="Sina_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="147"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="305"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM92918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="392" mass="44515" checksum="3461839C0B574354" modified="2016-11-30" version="1">MDGSPSRLEAVLRFKVDNISNVIRLGKILSEPTFAGNLPWRIKVQASKDGDKITELGFFLHCDGDKSLNWSCRAKATMKILSQEPATEPFQTFQRRIEHPFHAGQNDWGYAKFITWDCLMNPHSGYVKNDSVSLEVDMKLDDPAQSAATLKFKVENISRLETDQSPPAYIRNLQWRIEVFHAYQSTPKASLGIFLKCEGNRGKPGWSCGAVATIRIMPQKQGNMPFQRGIAHIFQPTFDDWGFAGFIDWQVLINPTNGYLKDDCIDIEIDVQADEPVGLEPQHDNDAMEQTDEGRLHVPSRYLECPICLELPRRQVYQCKSGHTICDSCINGVTTCPQCRERFGGERIRNRAVETMLDDLQMDCKFTGNGCTYKALRKHLPLHELHCVFNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJN5</accession>
    <name>A0A1D2MJN5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein CREG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CREG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001044">
        <property type="protein sequence ID" value="ODM93209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJN5"/>
    <dbReference type="OrthoDB" id="46836at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.110.10:FF:000004">
        <property type="entry name" value="Cellular repressor of E1A-stimulated genes 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343:SF17">
        <property type="entry name" value="CELLULAR REPRESSOR OF E1A-STIMULATED GENES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343">
        <property type="entry name" value="CREG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904127" evidence="6">
        <location>
            <begin position="20"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="7">
        <location>
            <begin position="163"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="37963" checksum="8D7BAD99FE6F3013" modified="2016-11-30" version="1">MKFCVVISIVPILFSVVCSNAVRTVVYRDGNALDSFEDDDFVDDWSPRAEYGAFASQRKGASLPLSKEKSRVIVANKNDVVIILRGESDDVEDYEDERVLQIPASDWKKSQNKFNSKVRKGLKNRFGTHKNFNPRNWQLTRSDFSDELSSSEELDDSDVYEPPPHQLVAKMARYIVHNSYWSSLATISTMPAVRGYPFVNLVSLSDGPNNNSTGIPYFYMTSLDMSSVDLESDNRASLMMTLAQTDFCEKHKYDPEDPRCAHVILSGRIVQVTNKAELAFASNAMFSQHPEMKDWPKDHGWFFAKLELTNVVVLDYFGGAVTVKLDDYFKQTLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK36</accession>
    <name>A0A1D2MK36_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001016">
        <property type="protein sequence ID" value="ODM93343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK36"/>
    <dbReference type="STRING" id="48709.A0A1D2MK36"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="529"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="592"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="733"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="449"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="767" mass="86254" checksum="6EC63B26B93F16C8" modified="2016-11-30" version="1">MEAGTAARSFLLRVFIVYIFAVLEGMDPVAYSISHDQLKRLKYGFPEQIFLFRTGGEGLMAMCSPVALMLYPFIVIALVYKKGQCNEEIWKAWLGPSLLYPLTGSIVNIIKIFAGRPRPTYFARCYGDSFKDYLDLGYKCTGDKNFVLEGLKSFPSGTTALAFASGTYIWLYVAGKSRMMAQPMLGAVKDGVWLASFIVVFPVMIAVSRVVDGNQHVEDVIVGALIGIVVANGLYFHYYPQLCSPRCYLMRDAPPYEEETLAQSDSIENPFFIHSLRHQRNAIIRVGDGSIHGNLELLEGYDQNTGGGGGWVEAESENEADIEMAAEFTATANRAAALENKISTQNSMAVQNDGGFDRVFKYVGSNGKYQYTLLLVVSIQCIILSWHHLSYVFLGAVPDHWCHIPELVGSGWTNDQIRNLSIPLKNNGEGWESCEYFNHNYAHLASLPYEKALTEASKMDVDDIGRLSCKQGWIFDRKTYESTLVTQFEIVCENRYLVATIQASHWAGVFIGSLILGSLSDQIIGRRKSVLISIIFVIVGGIAATFSRSYWELIFCRFFVAFGLAGAYQNCLCFVMEYAGTTSRSAMGMIQQLPFALGYMLMAGYAYFLRDWKTLQFAYSITAVILLSYFWILPESARWLAVSGQTEKSLKLLLKVAERNKKTVNREELYRIVLSCDARDAKRNPVTFTIAETPIPSRNVCLDWTRKVWHPIKKTLSIYLSLLATPEMRRRTLVIWFLFISVDLVYYGVVFDSATLTNDPYLLVFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKC6</accession>
    <name>A0A1D2MKC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000997">
        <property type="protein sequence ID" value="ODM93418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKC6"/>
    <dbReference type="OrthoDB" id="10579881at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="27828" checksum="4DFE6EFF7AEEB770" modified="2016-11-30" version="1">MPFCSFCNLQYFRTPMGAVKVVNVIFGAASLILVALSYVPVWTLAVFTGTVSGCLLLSLLYMTFYLLASSRFVHSKANRITCFIYHVLAGTALIVAGIELVGWSEYDSKCTHDCPKLYTIGIAKTLTFMNGTLYMIVGFLGVKDDDMLDTETASEENLPLLASTTLLTSVPGSHNHLYDHHNGRVSFDDIRSNFYHNRSHHNEYSFNNSCSSSVHSGSNNQYVINGKRTRNLTMAFSMPAGYKDLQIIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKN6</accession>
    <name>A0A1D2MKN6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000953">
        <property type="protein sequence ID" value="ODM93570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKN6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904186" evidence="2">
        <location>
            <begin position="26"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="15231" checksum="2A70FD1BE337D9BC" modified="2016-11-30" version="1">MAPLERKLFIVGLFILAQLALSVSSADSKKQQRYIIDQRWTRSEEEDCVEEPEPEPEGAAKKNGTSSDRQGKELTLGNPNDKYTLGNATAEPEPEGTGHNGTTGSGTNDKLTRNNSTTEAPATGTGSSVVATLSAVLGSVLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKX6</accession>
    <name>A0A1D2MKX6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000962">
        <property type="protein sequence ID" value="ODM93532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKX6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904197" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10104" checksum="802D2819AB1DCC8C" modified="2016-11-30" version="1">MMVVAALLAIVGLFSCVYRHPSSPYQFGGFSPKVTLWQTRPTSSTKSCCLNRGASPTGHRKITSFIKNMQPFSRSWATSSDILNCSKPECSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKX8</accession>
    <name>A0A1D2MKX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000944">
        <property type="protein sequence ID" value="ODM93623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKX8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="8750" checksum="472CA7A7B23A8B1C" modified="2016-11-30" version="1">MLGWVLFETQWETYSEGASSTLPPPPIRLPMLQNMLHHRVLSNRRRIMLPREAVSDTETHNHCKSLVNEWLKVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLH6</accession>
    <name>A0A1D2MLH6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12839</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000903">
        <property type="protein sequence ID" value="ODM93847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLH6"/>
    <dbReference type="OMA" id="AIIAQCC"/>
    <dbReference type="OrthoDB" id="201213at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02429">
        <property type="entry name" value="PTH2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042237">
        <property type="entry name" value="PTRHD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13335" checksum="A5A3EB0D96BE75F6" modified="2016-11-30" version="1">MSLVQYVILRKDLQTVLNWPLGALFAQACHASTAVLHLYKDDPNTVEYLANLDSMHKVVLQAPDMESITALAQKLTENKIDHKMWIEMPENIPTCIAIKPYSKNDVKGFVQKFKLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLM9</accession>
    <name>A0A1D2MLM9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein NPC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12928</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000923">
        <property type="protein sequence ID" value="ODM93754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLM9"/>
    <dbReference type="STRING" id="48709.A0A1D2MLM9"/>
    <dbReference type="OMA" id="EPCIFYS"/>
    <dbReference type="OrthoDB" id="4937502at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032367">
        <property type="term" value="P:intracellular cholesterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00916">
        <property type="entry name" value="Npc2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.770:FF:000001">
        <property type="entry name" value="NPC intracellular cholesterol transporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033916">
        <property type="entry name" value="ML_Npc2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF68">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904221" evidence="6">
        <location>
            <begin position="27"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="7">
        <location>
            <begin position="51"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="19255" checksum="90DB7059B50E2356" modified="2016-11-30" version="1">MAPSTKCSQILIIGLVALTCAVVVSSIPRNKNKIYTVNRWYALPGYSETPFSDCGSKGATIQKVEVIPCDNDNACQLKTGTNATFKITFVPKVNTTTLRARIHGIVAGIPLPFHCPQENACQNSNIACPIIAGQTYHYVVDLPVLKSYPHVNVKVKWELLSSVNQDVVCVTIPAKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLU7</accession>
    <name>A0A1D2MLU7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-nucleotidase domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12657</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000870">
        <property type="protein sequence ID" value="ODM94026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLU7"/>
    <dbReference type="STRING" id="48709.A0A1D2MLU7"/>
    <dbReference type="OMA" id="WHERNLI"/>
    <dbReference type="OrthoDB" id="409330at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008380">
        <property type="entry name" value="HAD-SF_hydro_IG_5-nucl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12103">
        <property type="entry name" value="5'-NUCLEOTIDASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12103:SF12">
        <property type="entry name" value="FI20020P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05761">
        <property type="entry name" value="5_nucleotid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="16372" checksum="B994977BCAA28D46" modified="2016-11-30" version="1">MAGGTGAIIKELEHEIETLNTPDFKSAMNWLQFLTSLLETYQDLEDPEAQEIIKEWWHERNLIRKKTKAIFNAQFGSLFRTHLNPTFFSKRLFRFADIYTSSVTNLIKYSTRHTFYPRRGEFLNSASSLPHEYRSWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMK7</accession>
    <name>A0A1D2MMK7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinesin-like protein KIF11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000836">
        <property type="protein sequence ID" value="ODM94257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMK7"/>
    <dbReference type="STRING" id="48709.A0A1D2MMK7"/>
    <dbReference type="OMA" id="CNASEAN"/>
    <dbReference type="OrthoDB" id="6436931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025901">
        <property type="entry name" value="Kinesin-assoc_MT-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13931">
        <property type="entry name" value="Microtub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin-associated microtubule-binding" evidence="3">
        <location>
            <begin position="492"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="681"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="571"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="698"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="714" mass="81998" checksum="EEBD224DDC223273" modified="2016-11-30" version="1">MKHTLLDNANANNLQLKARLASTLDRVDELQHLLKAHTETEKKLAGEADVLLQTTNDTVKTIESLHARLDRKKKVEETNLKHTDRFRKNLDKLLNDAEASLEKVKERNVLQTLDYFKLEDERKPLRKNLFDECHTVVSNTFNACMRINIQFTDFIEKLEKGTSHAIADSNMNFMVAMDNSDKSASSLKESLSDMVQAAKTQFGSMKAEINNLKTLIAKEFDQLEQDIKSTLSKDVAEFARLETVMTNLMSSFKTMAEQLDTNDRCFELRQQQYKGQYQQKITDMQRTLQELLTDTDEYVGGSAKSQKELVEKFSASREDCDTMLAEELKALQIAKAVPQETANKLNHYRERNVSSHQNHLTHLHEKVEERVQSTRQLEKKVSSVVTAHNEMLQERLTSVKAHNETINGTLKLFLNNANPCQTSLHKTYEHSREAFHKMLSNVADTESVFVSELHKSVDNQLEQLSDGLDRTANEIRKINGFQNEFWDVNYLKDLPTGATPMKREYQYPTKLSATSPHERVLSRYRSVSKTIRDTLVEQDSVVSDFSSTEMCVLVGESDGKNSVEERDRQKRESEVLEREQEERRLQRLEWEEQERQRLLLHKKTQVKLKKGVPFNEVLQDLARVKSPQEKMEEKNMDALMEKEGEIDLKDKNVTKCEVPRESSLDPVQNRPFSDGVLFEVSEAKENAVPTSKAAGGPSKKRRNSGGNKKKARSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMR3</accession>
    <name>A0A1D2MMR3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000851">
        <property type="protein sequence ID" value="ODM94161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMR3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904289" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="49" mass="4953" checksum="E0A833DCEDE27824" modified="2016-11-30" version="1">MKVFQIFAFVAAIIAVAMANVAPAEQAPAKNPKDCAEGTQACAAGCCPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNJ8</accession>
    <name>A0A1D2MNJ8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">(S)-2-hydroxy-acid oxidase</fullName>
            <ecNumber evidence="4">1.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_12212</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-hydroxyoctanoate + O2 = 2-oxooctanoate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:67940"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:133514"/>
            <dbReference type="ChEBI" id="CHEBI:176689"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:67941"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:16789"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:58123"/>
            <dbReference type="EC" id="1.1.3.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:16790"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anion exchanger (TC 2.A.31) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.15" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000802">
        <property type="protein sequence ID" value="ODM94462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNJ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MNJ8"/>
    <dbReference type="OMA" id="AQFITIC"/>
    <dbReference type="OrthoDB" id="1735926at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003973">
        <property type="term" value="F:(S)-2-hydroxy-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005452">
        <property type="term" value="F:solute:inorganic anion antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000056">
        <property type="entry name" value="hydroxyacid oxidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.570:FF:000002">
        <property type="entry name" value="Solute carrier family 4 member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.570">
        <property type="entry name" value="Helical hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="entry name" value="Mannitol-specific EII, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF127">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 4 MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="Phoshotransferase/anion transport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="16">
        <location>
            <begin position="646"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM94462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1007" mass="112322" checksum="232596F4A91AD890" modified="2016-11-30" version="1" fragment="single">NDGSETTLVYRKNQTSSMRNFGVEVRGIRDVDNLLKDATIILQPKSVILKDLIEEIIQHVSSSVDGNEAFFQQVYQGLFEDPNAQMFANTLQGFVKTESRAADYDPSWLCAFCNLAKIKKRYIAIVKMRQPTNFGETCQEVRFFILVLCPSKSVRVKREFMKETKTALETARTFATIFSDPNLRNSLLMVHSEDLFKNGLSEWAAKLSAISNQADTSTDDLKDAEENDSTKNKKCCGGIGSGIKEDLLRRLPHYISDYTDGIADGRAVQKTISTSIFLYFACLLPTIAFATLNSHTTNGRMDVKKGIFAQTVGQMIFAVIGGQLSLFVKIIFSLSEFFDIVDQFEAFYCCVGLWCSFFLFLSAIFNMSKVMKYCTRSTEEIFALFISIAFVVYAAKDDNYNSDACKNSQNVSLILKDNTSTNLNHSVYQTEAIGCRRDTMQGFEYDGSKPLLKLAPIQNLDWKMILVAGVLGFNLAVLIFMDQNIGSAIVNNPANKLTKGPSYNWDLVVISIINVFSSLFTLPWLHVALPHAPLHVKCLADIEERVEHGQIKQTVVRVRETRLTTIISHILMGLSLLLLPYPLSYILPSVFDGLYLFMGITALGGNQLFERILLIFTEQTSYPPNHYIRRVPQRKIHQFTLIQVIEVQNGLVCVDDFEKEALRKLGNNAREFYTSGADDELTVKDNLDSYSRSDLDSTANAERCFETRFVDNYFGEKGFSTLGISPSAFQRLAHPDGECGSAKAVEKIGGIFVLSVFATSSYEEVAAAAPNARKWLQFYMHKDRSITQSIIRRAEKAGFEAMVFTVDAQYVGKRRVSFRNPIRFPSHLKLPNATPDAAKDDLDIFRLHDILDHGVTWEAVSWLKSVSKLPLVLKGIQTADDAMRAVELGVDAIIVSNHGGRQIDTVPTTIDILPSILRAVGTRAEVYVDGGIRRGGDIYKALAIGAKMVFVGRPAIWGLAVDGANGATKVLEILRDELDLTMALTGVPNIKSITPDCVCRRDNLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNU9</accession>
    <name>A0A1D2MNU9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_11935</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000758">
        <property type="protein sequence ID" value="ODM94749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNU9"/>
    <dbReference type="STRING" id="48709.A0A1D2MNU9"/>
    <dbReference type="OMA" id="QKCGRNF"/>
    <dbReference type="OrthoDB" id="6735276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000508">
        <property type="entry name" value="Myeloid zinc finger 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000425">
        <property type="entry name" value="PLAG1 like zinc finger 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM94749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10770" checksum="F13445B234A1A639" modified="2016-11-30" version="1" fragment="single">AGSAAGAAAAPQKKFPCHLCRRSFMHKQSLDIHMRSHTGERPYSCADCGQSFSQRATLNRHRRRVHLPKSQQCNECGRKFGCRDYLVKHTYAHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPK6</accession>
    <name>A0A1D2MPK6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA replication complex GINS protein PSF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GINS3/PSF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000765">
        <property type="protein sequence ID" value="ODM94705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPK6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPK6"/>
    <dbReference type="OrthoDB" id="10251744at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21693">
        <property type="entry name" value="GINS_B_Psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055221">
        <property type="entry name" value="PSF3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22466">
        <property type="entry name" value="PSF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF3 N-terminal" evidence="3">
        <location>
            <begin position="51"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="346" mass="39747" checksum="A328D5393492F87F" modified="2016-11-30" version="1">MRVYQIWIFASTSDRKGKFRIVRCDLYLRVLKSIVDMSSKDLRTAYHPNYFSVENILASQTLIPCRTEMRLPKFGFLVPDCNSEDLPVGINLELPIWAARVLCRPLRTYVSVNIPPGFKEAHRECNELWIFLMIGNCREVFKEDPTVDLKKVNTNYYETGHLCTALFHNDAGELAEMLPEVLQQRILCIGSAVGATVRRNSPLHGEMMDILEEKLFKDSQESRIKLDDWLQPFELPPEVKEELRRPKPPPPSPPKQHHQQYLHRPFANQLPPAPAHSQLPPPVYGNPYAQLHQSGHPSPYGSMNMSSHQGLGMQNQNTSLQHQGHGQVQSHNHSHYSQQSHNMYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPS9</accession>
    <name>A0A1D2MPS9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="17">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_11905</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="17"/>
    <dbReference type="EMBL" id="LJIJ01000752">
        <property type="protein sequence ID" value="ODM94775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MPS9"/>
    <dbReference type="OMA" id="KPCMGIV"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.140:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05001">
        <property type="entry name" value="RNA_pol_Rpb1_R"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 17 21" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="14 17" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="20">
        <location>
            <begin position="240"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1508"/>
            <end position="1834"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="693"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1508"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1599"/>
            <end position="1802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1808"/>
            <end position="1819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM94775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1834" mass="202683" checksum="19457BB8B6EE4483" modified="2016-11-30" version="1">MAMTSDSRAPLRTVKRVQFGILSPDEIRRMSVTEGGIKFSEIYEGGRPKLGGLMDPRQGVLDRNSRCQTCAGNQSECPGHFGHIDLAKPVFHCGFLTKTMKILRCVCFYCSKMLVSPNHPKIREVVLKTKGQPRRRLAFVYDLCKGKSICEGGDEMDGLNNQDGDPAVQAKKSGHGGCGRYQPRIKRTGLEMVAEWKHINEDDQERKIIVTAERVLEIFKHIPDDECYVMGMDPKFARPDWMIITVLPVPPLPVRPAVVMYGSARNQDDLTHKLADIIKANNELVRNEQSGAAAHILSENVKMLQFHVCTLTDNDMPGLPRAMQKSGRPLKAIKARLKGKEGRIRGNLMGKRVDFSARTVITPDPNLRIDQVGVPRSIAQNLTFPEIVTPFNIDKMSELVARGNNQYPGAKYIIRSNGDRIDLRFHPKPSDLHLQLGYKVERHIRDGDLVVFNRQPTLHKMSMMGHRVKVLPWSTFRMNLSCTTPYNADFDGDEMNLHVPQSMETRAEVENLHITTRQIITPQANRPVMGIVQDTLTGVRKMTKRDVFLDKEQMMNLLMFLPIWDGKMPQPAIHKPIPLWTGKQLFTLIIPGNVNCIREHSTHPDDEDDGPYKWISPGDTKVMVEHGECIMGILCKKTLGTSAGSLLHICMVELGHEVAGRFYGNIQTVVNNWLLYEGHSIGIGDTIADPETYKEIQKTIRKAKEDVIEVIQKAHNMELEPTPGNTLRQTFENQVNRILNDARDKTGGSAKKSLTEYNNLKAMVVAGSKGSNINISQVIACVGQQNVEGKRIPFGFRKRTLPHFIKDDYGPESRGFVENSYLAGLTPSEFYFHAMGGREGLIDTAVKTAETGYIQRRLIKAMESVMVHYDGTIRNSVGQLIQLRYGEDGLAGEHVEFQTLPTVKLSNRAFENKFKFDPTNERHLRRVFDEEVMKDIMGSGEVISAIEKEWDYLQKDREALRQIFPAGDNKVVLPCNLQRMIWNVQKIFHINKRAPTDLNPIKVIEGVEALLKKCVVVAGEDKLSFLANENATLLFRCLIRSTLCTKRVAEEFRLSSEAFEWLIGEIETRFLQAQVQPGEMVGAMAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGTAARDAEKAKNVLCRLEHTTLRKVTTNTAIYYDPDPQNTVIAEDQEFVNVYYEMPDFDPSRISPWLLRIELNRKRMTDKKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSEDGSKFGAPGPDEEETADKMEDDMFLRCIEANMLSDMTLQGIEAIAKVYMHLPQTASKKRIVITDTGEFKAIAEWLLETDGTSLMRVLSERDVDPIRTYSNDICEIFTVLGIEAVRKSVEKEMNMVLQFYGLYVNYRHLALLCDVMTAKGHLMAITRHGINRQDTGPLMRCSFEETVDVLMDAASHAEVDPMRGVSENIILGQLPRMGTGCFDLLLDAEKCKYGIELPMGPGPDGMLGLGGTFFGSAATPSANSPQATPWNQGATPMYGDVWSPSSGMTPGPGFSPSAASDISGFSPARSPGGPGSPGSPGMYIPGSPGGVSPMYSPGSPGYGLISSPGMSPTSPTYSPHYSPTSPLGAGKSPSYSPTSPAYSPQQSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPTYSPSSPKYSPTSPTYSPSSPKYSPTSPSYSPASPVPASPTYSPSSAYSPPEDDERSTRRKGKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPY1</accession>
    <name>A0A1D2MPY1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine-rich repeat neuronal protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11749</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000733">
        <property type="protein sequence ID" value="ODM94931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPY1"/>
    <dbReference type="STRING" id="48709.A0A1D2MPY1"/>
    <dbReference type="OMA" id="IGQHLGC"/>
    <dbReference type="OrthoDB" id="1687175at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF168">
        <property type="entry name" value="GH22922P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904362" evidence="5">
        <location>
            <begin position="28"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="509"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="538" mass="60898" checksum="308A08C5C2EC4809" modified="2016-11-30" version="1">MGRIQFRTLKITAILFLFQTLYSFCQTEETTESIGNSSLLCETDNDTIGQHLGCSCTFVGTMEKILKADCSKQWIGSNDTRLLPPRLNVSHHVKILDLSENQLTHVNMETFGSCESVEILQLNDNGMQLFEGLSCARLLSLDLSRNKLQNLTSLALANMVRLVELDLSFNELLFLEPNTFEPLKMLRRLNLGSNLLGMELFYMENYVLSLKNLDRLEELDLSNSSLPDFPEYLINGTTHLKKLKLRDNLIQLISNGVFEQMHELKTLDLSGNLFETLEPYQFVGLQKLQTLVVDKMITLKSIQEHAFAGLTSLHELSCQTNYHLTLIDPMAFRGDPETEAGDCNPKIVRLGDNDLRFIDYPLLSWKDIDILELHRNSWVCDCDLQWVSDFYKHKPKEAAILGDSYFSCYEPHIFAGVPVVAVNPEEMLCFSPVATVAGTIGIIVFGILLFSFCTVIVLNQMGMLPDWVRQYNIFGSGSSLPTYTRVNPKPSTKARRMVERGQALPDLHCYTTTTTNNSKSREPTADDLEWDNADIGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ29</accession>
    <name>A0A1D2MQ29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein dachsous</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11682</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000724">
        <property type="protein sequence ID" value="ODM94998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ29"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ29"/>
    <dbReference type="OMA" id="YLLNWSP"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000015">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000106">
        <property type="entry name" value="FAT atypical cadherin 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.900.10">
        <property type="entry name" value="TCF3-CBD (Catenin binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027397">
        <property type="entry name" value="Catenin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026">
        <property type="entry name" value="FAT ATYPICAL CADHERIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026:SF136">
        <property type="entry name" value="PROTOCADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="8">
        <location>
            <begin position="68"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="8">
        <location>
            <begin position="196"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="8">
        <location>
            <begin position="291"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="577"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="721"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="499"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="579"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="735"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="861" mass="92809" checksum="DF53F4DFED78630A" modified="2016-11-30" version="1">MSSGSADNYFTIGTHTGQILLARPLEKSAEKEYKQRVSVDCMNKAKCMASTEVIIHINEATSTSLRFPQEEYKVSVSESASVGTNIIQLLNELEPFTFANNEEDHDAFSDHSSDNNTVSFAITSGNEDGSVELNPYTGRMTLKRSLDFDSKPLHRVVVRAQDHDTRHWALAIVDIEVKDENDHEPFFLFPNYLEFVGENEPVGTSVFTARATDLDQGLYGKLNYSIFGGDGKDKFRIGTQSGVVTTNAVFDYESKNRYTLKISASDLGGKTCSAEFVVEIESRDEFAPQFAQKSYKFLVPINAGKEYSVGRVEATDRDMGRDGLVRYNLLSGSSSLDNFKGPFKVNVTTGVISVRGPLRAHENRNISLTVVASSGKEDSKVAEALLEITVGAPSQELEAAFTTSSVADWVLGLLVTTLLVLFLCCTVFLVLHLRNKKQSKQEKAQVFNSASNFGTLEYGAQSTMVLNSSQPGSLYDSHHQQYSDMVDMQVGERRCGVNNTASEISDQSNSASSGRGSAEYGEEVEDEEIRMINEGTLAQHKFRDSVGIPDSGIQDEDNVSQSSAKNTQEYLARLGIRPKIPDHGHPDPKMRLHSQDSISNMYHGDDGGGGSGGGGGVSSSSSINGGAGGSSDPVDISNLIYAQIADDVTDSEMMDESRATYSTPGGAHHHNGSLSSIVHNEEELTGSYNWDYLLDWGPQYQPLAHVFSEIACLKDENNARIGGGGGNSSDRSNSEASNPHFSEQSYGRKSGSHLKGKVIAAAGGRGMMVGGGGPSGPTSSMVAARHAGIPPSMHILPRSPISHDSTFASGLISPSFSPALSPLANRSPSISPLGGASTNAVIRTSQYHQNYSSSSDSEFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQA8</accession>
    <name>A0A1D2MQA8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-globin transcription factor CP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11423</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000693">
        <property type="protein sequence ID" value="ODM95257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQA8"/>
    <dbReference type="STRING" id="48709.A0A1D2MQA8"/>
    <dbReference type="OrthoDB" id="9996779at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007604">
        <property type="entry name" value="CP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040167">
        <property type="entry name" value="TF_CP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037:SF21">
        <property type="entry name" value="GEMINI, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037">
        <property type="entry name" value="TRANSCRIPTION FACTOR CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04516">
        <property type="entry name" value="CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51968">
        <property type="entry name" value="GRH_CP2_DB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Grh/CP2 DB" evidence="3">
        <location>
            <begin position="249"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="33469" checksum="84C7509F5D914DB7" modified="2016-11-30" version="1" fragment="single">MYWPSYHVGSTGNMSTTDVRTPRPAKTPAWSVPPMMTSPMEDPSSCSDNASDNSDKLESFCQAPVQNPASKTRKRKIVSSSGGTSFMNAGAMNGVMESGAVTGRGGSHNAGEHSGPHNKEMGGDARNSGSLWADAESLAADFDGSLSGLGADLSNNSYDMSEALLALPSLYNNRNASTNSSPQAANPNVPSGFIKEAGLTPLAAAHLHGGSSVSLPGDFHFEAHSSSSCPQNSSGNAGHHHPQDPIHLDCERRFQYVLAAATSTATKVNEETLTYLNQNQPYEIKLKKLGELTAYRGVVFRSIATVFGTRADCIMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQQ6</accession>
    <name>A0A1D2MQQ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">26S proteasome non-ATPase regulatory subunit 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11486</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000700">
        <property type="protein sequence ID" value="ODM95198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQQ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MQQ6"/>
    <dbReference type="OMA" id="KTGRHEM"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="32"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="27814" checksum="6830C9B0DC73A4F0" modified="2016-11-30" version="1">MDRLLRLGAAMPGLGQGGPPADGPIVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLRQTGRPEMVVGWYHSHPGKVVIDAFRLINPNMMVLGQEPRQTTSNLGHLQKPSIQALIHGLNRHYYSISINYHYSDHCKMNESTLHSMLDLAKAYNKALEEEEKMTPEQLAIKNVGKRDPKRHLEEQVDQLMSANIIQNLGAMLHTIAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRA9</accession>
    <name>A0A1D2MRA9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_11046</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000641">
        <property type="protein sequence ID" value="ODM95639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRA9"/>
    <dbReference type="STRING" id="48709.A0A1D2MRA9"/>
    <dbReference type="OMA" id="LMIVHEP"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000006">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054473">
        <property type="entry name" value="KIF2A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22923">
        <property type="entry name" value="KIF2A-like_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 13" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9 12 13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="16">
        <location>
            <begin position="250"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="113"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="626"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="340"/>
            <end position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM95639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="722" mass="81351" checksum="7A1C4856F8847416" modified="2016-11-30" version="1">MQRRVHTAVVSGINWEGKSVTVEWFERNETKGKEVDLESLVALNPHVTTRNLVPNNGTGPMENVTNNISSNINVPNNQNTGNSRQTIAEMRPPAVPSGVAGKNQLNTGNVITNVPANNGGRIPRATRTTQLAPPSGKLADTPINDIEDQPMDTTSHVNGGGTVTRADQSQLSNTAPASRRRSNVVKEVEKLKKNREERRLRQAELKNEKENLMNMDPGNPQWEFSNMIREYRINLEFTPLRDSDVVEDYQITVCVRKRPMNKKEVVRKEVDVITVPNKNQIIVHEPKQKVDLTKYLENQHFRFDYAFDETCSNEAVYKFTARPLVQTIFEGGMATCFAYGQTGSGKTHTMGGDFNGKTQDCQKGIYAMTAKDVFRFLKMSQYRQYNLAVSCSFFEIYSGKVFDLLANKAKLRVLEDGKQQVQVVGLQERPVDSVEEVLKLIQLGNAARTSGQTSANSNSSRSHAVFQILLRQTQGRMHGKFSLIDLAGNERGADTSSADRQTRMEGAEINKSLLALKECIRALGRKGAHLPFRASKLTQVLRDSFIGEKSKTCMIAMISPGLSSCEHSLNTLRYADRVKELAAHDPLETKMSSVPEDDLETMESESELAQLRSLNEGEISGELLTFHETISKMQEAEEEMVEYQKLIFEANNRWITKEKMLLALTNQVEYDQEVYSQQLDELCLEKIAMLTELRNKISKFRNYVTEEETMSKKMTNSATPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT33</accession>
    <name>A0A1D2MT33_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G patch domain-containing protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10587</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000582">
        <property type="protein sequence ID" value="ODM96092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT33"/>
    <dbReference type="STRING" id="48709.A0A1D2MT33"/>
    <dbReference type="OrthoDB" id="10019757at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032436">
        <property type="entry name" value="URB1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF9">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16201">
        <property type="entry name" value="NopRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="3">
        <location>
            <begin position="640"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="765"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="839"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="854"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="865"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="913"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="923"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="968"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00040365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="994" mass="112711" checksum="E1053A8FD9196D08" modified="2016-11-30" version="1">MSSKLKSKKKSKKMTVKLEVEESGEAAENNALLFERMEVEEEVEETARENGSHESPEIFQLLEEASGLQLVKLLISNTKSVFKLLSNPELLQRFSQISSKIQKVCDKHKRTEVKALKFISKVFSEVGVDELSCDSDLFKAFLKHGMKSLENAESGPVIVGILQGIFSVGAQVGQVKNPTLGIQMIVSHSKASDIFLESHKEVPKKPYNFTQKPQQHQLQIKSDPDKGPEQKYSQIKTQLLKLWKNLVVAFTKISKKDGTPNDKKVLENSVPYLMQMYGATMSEADQEIFEILQLYTGRKLQISIESLPLFGPKCFEPLPQRASNPLFAHSSRANTILNLVNEQQAFLTAMEYNEGNEIGFANPKHYDFRFLLPLLCNTIDAKNICDSVKVVTNGWIYFIMRGLSFEDATLRNMAFLSFKLLIENFQLPKKGVRAQDIKVWLHFLLSIRKGFQNLGTCKASNLLSVWMVGTWEAVRQATHPMYPRLTNFLFAKPVIDLTVLPDFLPFYNAADGNRDTREWILKVLAHGLKTREDWQVAQRNPTINSLCCSFLVENVFVRRSIIKILSGGARIPEVAQEMVDKHCLLIWISNVPTSLQMYRRELGELFKTLRANCPPNDSRNLMFEFVARKHDWYKLVLKEGMDFARKQLEKFGWKDGSGLGKNEQGMLTAIKPTLKVGKEGMGFDFSKELVDTWWTRAYDDSLKRINVDENDASDIVGVSLQDGENDGSLQGGGLVKDEERPFIRMKKRMMKATFTTFSKGATLSNGEMVTEKLSSDESDDESGAKSKDTDETNNASKSLTDEELFQACGGRTAHKGARFGLKLSGKLARIAAQEEALKEIFGKSQSKTKPEKSTPVTDTDLCNSSKKKKKDKKRKSKHSQEPDPVQPEEDYNETEVLPPPSQVSEPETHEITSDLNDQNNLISKRKQKKHKKRKYEMLQEEENIDEPLNNDMISESPLSEPDDELVPKKKSKKSKKHKRSKDKRENESCELISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT91</accession>
    <name>A0A1D2MT91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Importin subunit beta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10394</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the importin beta family. Importin beta-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000555">
        <property type="protein sequence ID" value="ODM96297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT91"/>
    <dbReference type="STRING" id="48709.A0A1D2MT91"/>
    <dbReference type="OMA" id="QQYQERW"/>
    <dbReference type="OrthoDB" id="10263328at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000027">
        <property type="entry name" value="Importin subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="29"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="421"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="902" mass="98885" checksum="425B9A555C997B5E" modified="2016-11-30" version="1">MNSTDSAAVMLVQILEKTVSPDQNELTSALQYLEEAANSNFPQYIKSLSEVLVHAGHSPVARMASGLQLKNLLTSKDPNVKAQHQQRWLLLPEDIRVYVKKNVLAALGTETTRPSSAAQCVAYIAVIELPHNQWADVIPILVGNVTGHAGAHPSAELLKEASLESIGYICADIEPEVLIRQSNPILTAIVHGMKRDEPSNRVRLAATNALLNSLEFTRSNFDTETERHFIMQVVCEATQVPDTQVQVAALQCLVKIMSLYYQHMEFYMNQALFAITMEAMKSEVDEVSLQGIEFWSTVCDEEVDLAIEASEAAELGRPPQRTSRFYAKGALQYLVPVIIQTLTKQELQDDDDDWNPCKAAGVCLMLMANCCEEDVIQHVIPFVQTNIKHENWRFREAAVMAFGCIMEGPEPATMKPLAENALPTLISLMKDENVAVRDTTAWALGRICEVVSDAALNPNHLPPLLEALVAALSAEPRVAANACWALSSLAEAAYESASEGRNDDNKEPDTYCLSTFFRPIVDQLLNTTDRPDGNQANLRPAAYEALMEMIKNSPRDCYETVQHTTLIILQRLRTILMLGDQTSGSDRTQYNELQSSLCATLQSVLRKVTPQDAPNISDAVMEALLQMLSGPGGRSGGVQEDALMAISTLTEVMGDGFIKYMDAFRPFLLVGLQNVTEHTVCSAAVGVSGDICRALGNKAVPFCDDIMSFLLQNLGNSLVHRSVKPQILSVLGDVALAIGTEFKKYLEVVLQTLLQASNAQVDRNDYEMIDYLCELREGVLEAYTGIVQGLRGDWPAAGFPGGPVNADLALIQPHLPHIVQFLCEISKDPEKSDGNIAACAGLIGDLLVGYGAVILQLLDNEVINELLTQGRRSKTGKTKMLSTWATKELRKLKNQTSAAASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTC7</accession>
    <name>A0A1D2MTC7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ribonuclease ZC3H12C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000555">
        <property type="protein sequence ID" value="ODM96293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTC7"/>
    <dbReference type="STRING" id="48709.A0A1D2MTC7"/>
    <dbReference type="OrthoDB" id="392925at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036464">
        <property type="term" value="C:cytoplasmic ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021869">
        <property type="entry name" value="RNase_Zc3h12_NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051101">
        <property type="entry name" value="ZC3H12/N4BP1_RNase_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12876:SF35">
        <property type="entry name" value="LD08718P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12876">
        <property type="entry name" value="N4BP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11977">
        <property type="entry name" value="RNase_Zc3h12a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase NYN" evidence="2">
        <location>
            <begin position="394"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="485" mass="53771" checksum="23F7561F6FD3E3F0" modified="2016-11-30" version="1">MKTRSGRGKKSLEPVRRSPAKRRKRPSKRQRQRQSGLVIKPENQENETIVLSDSEGDENQPNNNGCVEDDIQVIDIADITQEVAAPHVSVNVSKCLDNYVTAQPATSASPKPKPVVFYVNQEVAPPSVSNANVSKSIGDYVTATTQPSTSSPKPVVFGRPSGNNTSSDPPVIILGDEPDLPVPDDDGVEVVAVVVSSRQTGRSLNRRKSTSLSQMQEAIKKAKSTIRRQSSSRNPSPSRHVLNGIAANSRQIQKSKKWKKQKRSYQNNQQFQGINAFQRNRRQEDQRRVVYRIDNHRDGAGPWERIGGNAPTMQNRNANFSFEAIPFIPFASSTPAPRRPNVVRDRCGPWSRPRLPLPSGSNQMNPPRHPIPSIAPGSNIMTVGDSGKRQAGSLRPIVIDGSNVAVGHGKMLRTNKFSAKGIQICVDYFLKRGHNEIFAFAPRHFLKKSESLDPELLEKIEKDGYVRFTPSREVGVQRISSYDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTY6</accession>
    <name>A0A1D2MTY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000544">
        <property type="protein sequence ID" value="ODM96392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTY6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904527" evidence="2">
        <location>
            <begin position="21"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="293" mass="31271" checksum="3647C0A7A32C00B2" modified="2016-11-30" version="1">MRFRLCFCIVLVTAVVLASAKKNKKDGNKEKNPGQSKKGLQNLSLCLGEPVALNVQPESVDECLTAKFNEIIATFGNSTDEKSTKKLAKKKQKLSKKLKKKCMTECEWKVVGLIPSGEGNSTGNTSSTADSTEKFSKMFPEAAQAEIKNAIESCLNTQTKSEIRKGANINKANQMCSQNKRITKCLQKSLNRACRGKGRQGGTATSATTTTQTPAVGSSTTGTPSSPSSVSSSSSSPVSTVRPSIAPDDDTGDDDNDDDDDDDDLDKDDDEDNDLSKTSPSSPSLNTAKPITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU83</accession>
    <name>A0A1D2MU83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Minor histocompatibility antigen H13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_10033</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000517">
        <property type="protein sequence ID" value="ODM96647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU83"/>
    <dbReference type="STRING" id="48709.A0A1D2MU83"/>
    <dbReference type="OMA" id="FLYDIWW"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM96647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="37637" checksum="797F7DF145DC608F" modified="2016-11-30" version="1">MADAEKVGQVLGQNNVTNGTTGKIPATPEGMAIAYGSLVIMALLPIFFGAFRSVKHHKEQKANYQDTGEKPDTMSHKDAAMFPLIASCALFGLYLFFQIFSKEYINLLLTVYFFFLGILALSHLLSPVITKLVPAGIPNVHYHIHFSQKQKVGEDEYVLIDYKFTTYDIICLAFCSVVGVWYILKKHWIANNLFGMAFAINGVELLHLNNVVTGCILLAGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLAADNFAMLGLGDIVLPGIFIALLLRFDVHLSRNSRTYFNISFLAYIAGLFTTIFVMHVYRHAQPALLYLVPACIGAPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUY6</accession>
    <name>A0A1D2MUY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reticulocyte-binding protein 2 a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000490">
        <property type="protein sequence ID" value="ODM96910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUY6"/>
    <dbReference type="OMA" id="HACARAY"/>
    <dbReference type="OrthoDB" id="2386367at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045058">
        <property type="entry name" value="GIMA/IAN/Toc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903:SF184">
        <property type="entry name" value="GTP-BINDING PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10903">
        <property type="entry name" value="GTPASE, IMAP FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00457">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MACPF" evidence="2">
        <location>
            <begin position="609"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1106" mass="126010" checksum="70510EA5086E5A36" modified="2016-11-30" version="1" fragment="single">IYSVKGSPDSSTFCAVLRSHENGLENQFLPIGDGKVVGNIGSEYASSSQSWNTSRGYWDVGSGCELTACEDVYLGGRCSVFEGSRFTTTNSKRWLSASCKCNKKCNCSDSEINFQHHACARAYLEPGGCNVCDAKYMELEGSNSRFPEERRDKIGSLQIRSGCSIIVYEEEDFEGDSENISVPSLQNWNGTIGSYECHCGDDTHSELNEIRPVAVPRQGESPVQLQIPDSLDEIVAQIRQHNYTHPGLLAAFSSLTHGRSSKNAYILLIGSSGSGKSSVINILLNNPNVTLAGDVASTTSDILEFRIPIPAAEFGVSNSELRVIDTPGLMDSRGIENDAVFLATLDDYLSGHEELKNRIPNLIIVMEHFTENRFSGPGAKFVHMILALNSFRTRITDENYSNVVFAFSHFCSETSKAVLSNPSQKLMRFKDVIEEFSLFPKPILTAVIENQGKENELLMVNNNYILPNKELFPSNLLDKFDTITRKGKDEMGNAILSAAFRNRRGHLNMSESVFPMVSRNHPKVAKYLGKLSSAVLSFTSTEISQQLASTYDGMPSRLKSRFPTKTLEYIQKYLNLRNIRTMQDVPKTSGAILELLEEMDKNEGVLYLLENGLNLKAPLFPQSVVTGNSFSLFQDSVLPISPYKTDVLKTSEMGFRFPESTKFKKNSDNFNLLTIFDTRKQYVRHRLQSFGINTASINNTDAFTVLNSQTKEGFFIKNAQCSNNVCTFVASRFFKLFQLDLEERATLNPDFIRRVRNLSPLNESNYESIQLWNDFFNDYSTHVVKSAWGGGRIDIHVTVRPSTISVQSFQDKLFKAVEFAEDLNSLISGEKIDPKRLLPTGVNYSLAFHGGNPSYHTTDLTALSLEDASKIMRNWKKSLKMNPAVIPVELISIGRVAQSLGFEKANYIHEAASRYLNSALDYVPPTPDPKVLEELARQQRETEKRLKQLAEEKKRQEEQAERDRLAAIELQRQREREQKRLEEQMRRAEQERQRKLEQERQRFLKQQEEERRRAREEERRRQEEYERQMAMIREREAEERRHAEQSRRWREEEEERRRQQNVFYHINNHVRNTVQDTRRGAENVWNTVNRGVDDTARTVSGWFGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV19</accession>
    <name>A0A1D2MV19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000499">
        <property type="protein sequence ID" value="ODM96836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV19"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904586" evidence="2">
        <location>
            <begin position="20"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="19359" checksum="9DC951584FC31730" modified="2016-11-30" version="1">MKGFVVTALVIGAAGIVTAGIGGGFSGGGFGGGGGGGAVRRWRWVWSSQRSGGGGGGFQPAQFSEGPSSDGIVDQALLAQVAQVLSQQGGGGGGGGGYSGVGGGGGGSSQYGAPQPQSGYGAPSGGGGGGGAQLDSPRKAQLVGSFSSSSGGGGGGGLQWRWWRWQQWRVRTLVQFSLIQRLQALVQPFENSKCHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVQ0</accession>
    <name>A0A1D2MVQ0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metalloendopeptidase</fullName>
            <ecNumber evidence="7">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09692</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6 7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000480">
        <property type="protein sequence ID" value="ODM96988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVQ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MVQ0"/>
    <dbReference type="OrthoDB" id="7544260at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811350" description="Metalloendopeptidase" evidence="7">
        <location>
            <begin position="35"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="8">
        <location>
            <begin position="53"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM96988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="386" mass="43663" checksum="B9EF84875081F159" modified="2016-11-30" version="1">MAHSARKMLRKPTKSAWLLAIFVQIVTFFQLGACYTCETPDDWLSGNIGIQLAARGQLEVFHQTWPNGVVRYKLHSSLTLDDTSEVLKAFDEFHKKTCIQFKPWQERDTDFVSIEVDDNVCGFANVCKIGGWQVAKFGKDCRNMKTMVHQLAHTLCLGHEHQRLDRDQFLNYSSCSSNPRKVESLKRPTSLYNYASQMHSKCGSCDRGMPNEGKIHSSSTKNVICGPDASPGLSVLDVDNINYLYNCQGCQRHRWVPAMSLSQEDFSKMPTFGYETRNKKPIFACRAQHQAEIVSGMYDHARQSCNISYYDKPYEIQGPVEVLTIPGGVVGDDCCVYKLVNKKNVLEQENFLIYVGNIISQQFWNWTSHVAYAHGGGLKSSRKGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWC9</accession>
    <name>A0A1D2MWC9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Barrier-to-autointegration factor-like protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Barrier-to-autointegration factor 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09316</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000450">
        <property type="protein sequence ID" value="ODM97363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWC9"/>
    <dbReference type="STRING" id="48709.A0A1D2MWC9"/>
    <dbReference type="OMA" id="SKQQGDC"/>
    <dbReference type="OrthoDB" id="9997163at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.40:FF:000002">
        <property type="entry name" value="Barrier to autointegration factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.40">
        <property type="entry name" value="Barrier-to-autointegration factor, BAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051387">
        <property type="entry name" value="BAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004122">
        <property type="entry name" value="BAF_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036617">
        <property type="entry name" value="BAF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47507">
        <property type="entry name" value="BARRIER TO AUTOINTEGRATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47507:SF6">
        <property type="entry name" value="BARRIER-TO-AUTOINTEGRATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02961">
        <property type="entry name" value="SAM_BAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01023">
        <property type="entry name" value="BAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47798">
        <property type="entry name" value="Barrier-to-autointegration factor, BAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00079764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM97363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="90" mass="10122" checksum="35743620999D12D0" modified="2016-11-30" version="1">MGSTSQKHRNFVLESMGEKPVTDVAGIGETYGKRLTSQGFDKAYVLLGQFLVLKKNEDLFVEWLKMTCGATAHHATQCYKCLNDWCNAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWF9</accession>
    <name>A0A1D2MWF9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000448">
        <property type="protein sequence ID" value="ODM97390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWF9"/>
    <dbReference type="STRING" id="48709.A0A1D2MWF9"/>
    <dbReference type="OMA" id="PIAWHAR"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF65">
        <property type="entry name" value="KINESIN MOTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="308"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="52"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="42999" checksum="FEBE452002553ACD" modified="2016-11-30" version="1" fragment="single">HGNSNAKPKNATYGFDRVYFNQDTNEDIYNEVMKPLVGTLLQGYNCSVFAYGSTGSGKTFTMLGGKDSPGLTLLTLRDLYQQLDAAQDDYQSDVIVSYLEVYNEQISDLLNKSSGSLQIRDAGRGNEAVIVNLSEHRPPNVESLLQLLQAGNGNRTQHATDLNAESSRSHAVLQVHISMRDKHTSMETVSRKAKLVMVDLAGSEKGSATGFTGERFREGTNINKSLLSLANCISALSGGKACASFRDSKLTRILKDSLSGNCRTVMVANVSPADTMKEDTLNTLKYASQAKKITLQASQNTMTVQTCLSNFTRVVEEMAEKIEHLQDEQKTKDDLLESQKLELVAKDELIESQKQELEDKDLELRLLQEKVKAQKLKLMKLYQRKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX11</accession>
    <name>A0A1D2MX11_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL21</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L21</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09091</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000428">
        <property type="protein sequence ID" value="ODM97597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX11"/>
    <dbReference type="STRING" id="48709.A0A1D2MX11"/>
    <dbReference type="OMA" id="HVQASRC"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="18168" checksum="45BA9A511AA468EB" modified="2016-11-30" version="1">MTNPKGVRRGTRDLFSRPFKKHGLIPLSSYLKAYKVGDIVDIKANSAVQAGMPYRFYHGKTGKVYNVTKTSLGVIVNKRVGGRVVAKRINVRVEHVQHSKCRSDFMDRVKMNEHLKKEAKINGLRVVCKRQPAQPREAHFVSARNNEPILLTPIPYEFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX49</accession>
    <name>A0A1D2MX49_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000436">
        <property type="protein sequence ID" value="ODM97511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX49"/>
    <dbReference type="STRING" id="48709.A0A1D2MX49"/>
    <dbReference type="OMA" id="FISTEEH"/>
    <dbReference type="OrthoDB" id="10610539at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="303"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="684"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="733" mass="82592" checksum="70C8A4BB98883D1B" modified="2016-11-30" version="1" fragment="single">MADKKPVEVPQTTGGTEKGQDPSEEEKRTSKDTTGTTGTDESGSGSTPKETPQQGHDAGGGIMGIFPKIPGLPQIGGHRAWGKWAPPPPKPEGEESLHEVVEKLRAKETSPARSKKAKPEKIVEEPEQAPKRKEPAPPKPEKAKRDPTKKKRKVTVYNVREPKAKPDEIQEEPEPKELPPPPKPEPVVIQPEPVKKPVPPPPPPAQELPPPPPKPEPKEIPQAPKELPPPPPPPKAQLQEVKQEPVQQPVPKELPPPPPKPEPEEIKKPMTKELPYNLDVQSLIPSHMVKSVKIKKVKKTEAIRKHVAPPRDDDKPTGPVASKVVFLKRPDEPPKATEEPPPEPVVEPMPEPEPAPEVPKGVIQPEGITDINGLPMFLVTDTVANLIHITNEDKLIDKRLSELIDVHRGDMLKKLKKKQQTKIPTYTYAEMMKMLKDQGIPCPTNEDFSRLHGLHSRWDPDFTVLEYFSPMLRTFVPINMRSAKNIAVSPLLRVNGINAKLEIIKYRGRYRGCWTTDDCIKGLDISKVPPKREALEGFVQRGRHENTQKKYDEMSKVALDEAHLDYLIEIQSYQAETLPIPIFYDMLHLGMEVANENLRILVEEDGYPPNDIIFISTEEHAQQLKRKIQLYGALGLETLESKRKGLGQYLPQWLQTRDEVVREIMNRKDNEWYTRLTKTENEGKVRENIRKGEDPRKSIGTSKIRASFSKDARKVHPETHAPGDNKGHLKHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZN2</accession>
    <name>A0A1D2MZN2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000348">
        <property type="protein sequence ID" value="ODM98496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZN2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="20990" checksum="4587C8AAAC1A0462" modified="2016-11-30" version="1" fragment="single">KLAIRMSRGAVLSSEDVSWHKNGCLYRRFMEQDRQTCLQTDDEIRRQLTLKYKKEALVLRTALKKKNRKTSTRRSHNVVGLTPHEEALVKQKVEEQLSPNGIIRWYLDSQRKEFEDTKQRFYQQCNCVKVTGNIVEESLPKPEVESITVTPEVDAMLVSKKENASVTEDDDEDDAWSVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZX3</accession>
    <name>A0A1D2MZX3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000341">
        <property type="protein sequence ID" value="ODM98586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZX3"/>
    <dbReference type="STRING" id="48709.A0A1D2MZX3"/>
    <dbReference type="OMA" id="FRTMQET"/>
    <dbReference type="OrthoDB" id="10249567at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="28"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="201"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="357" mass="40255" checksum="B386D3AC57251941" modified="2016-11-30" version="1">MSQTPTKRRCLGYGPESVSLVGETNVDPFSFLWTHRNCSTSAACPVIESPVFHGGTKSNHGWMLSICPKRRLKGDEYCSVYLTLKERVKEPLKTLFKISILDANDRPVHQNELCREFGKKGMYIHGFDTFILSSALTDPARPLIENNTIKIQCSVIIVDEMEKKVSVGMSYCIPSDEKRNEEFKSRFAKDFGKMFNESNGTDVIISTSKTTFKAHTFILKARSPVFDRMLTVDMKEKESNVVQIADFDEDVVKGMLEHLYTGQTDFISTLAPELLQIADKYDLAGLKQDCEYAMVKRLNIGDAATVLVLADTHNAPFLKEKTLAFINLNKDEFLKTAAFQDEFIAHPVAFADLHLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N077</accession>
    <name>A0A1D2N077_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative integrase/recombinase y4rA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_08019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000337">
        <property type="protein sequence ID" value="ODM98640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N077"/>
    <dbReference type="STRING" id="48709.A0A1D2N077"/>
    <dbReference type="OMA" id="IARWIRT"/>
    <dbReference type="OrthoDB" id="6769862at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47823">
        <property type="entry name" value="lambda integrase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="93"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="302" mass="34122" checksum="20124C196E6F3144" modified="2016-11-30" version="1">MQSWAKSTIKQYDSALRNWHQHTVSHNVNLFEATAADVMTFLRQRFDSGSSYSAVNTARSAVALLLSPQNPAIISENQFVKRVMKACFRIRPQIPKYSQVWDVTVVLRYLEQQYPNEQLSLQQVSKKLCMLLCLATAARTQTLASINVNDIVQQPNGIKIRISKMLKTTRPGFHQSEFDIPYFEEKPSLCVGTLIMHYLNMTKDLRKSSQLFVSYQKPWNPVGSQTIARWIRTTLSEAGVDISNYGAHSVRHAASSTALKAGVSLENIRASAGWSKDSLTFQKFYKCPIEASFEFSKAVLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0P6</accession>
    <name>A0A1D2N0P6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_07803</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000314">
        <property type="protein sequence ID" value="ODM98877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0P6"/>
    <dbReference type="STRING" id="48709.A0A1D2N0P6"/>
    <dbReference type="OMA" id="VLRCFDN"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000003">
        <property type="entry name" value="Obg-like ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000029">
        <property type="entry name" value="Obg-like ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="10">
        <location>
            <begin position="22"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="11">
        <location>
            <begin position="302"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="31"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="397" mass="44631" checksum="EA6684C9B4578783" modified="2016-11-30" version="1">MPPKKEQPQERAVLLGRVGTNLKVGIVGLPNVGKSTFFNVITKSAIPAENFPFCTIDPNENKVAVPDDRFTYLCEFHKPLSKVPAFLNIVDIAGLVRGASQGQGLGNAFLSHIRACDAIFHVARAFEDDDIIHVDGDVNPVRDLETISEELRLKDEEYLLANLEKLEQKVVRGGDKKLKPEYDVFCKIKTHLVDEKKQIRMCDWKEADIEILNKHLFITAKPIIYLVNLSEKDYVRKKNKWLIKIKEWIDKHDPGAMLIPFSGGLEFKLVDMPEDEKAAYLKEIGAQGALDKIIVQGYKALQLQYFFTAGPDEVKAWTIQKGTKAPQAAGRIHTDFEKGFIMAEVMKFDDFKEEGTEAACKAAGKYRQQGRNYVVDDGDIIFFKFNAGAGLAPAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1D9</accession>
    <name>A0A1D2N1D9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative PPE family protein PPE13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000330">
        <property type="protein sequence ID" value="ODM98725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1D9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904886" evidence="1">
        <location>
            <begin position="26"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15223" checksum="D6ABE1317B4ABC43" modified="2016-11-30" version="1">MKPSNCIANLISAQVFVSLMSYAECCNFGPGNLGFLNFGTGNVGIGNFGFGNGGIGNKGFLNGGFLNTGFAQLGLRNIGALNLATIPNTISVFNVPLAPNLTPPIPLGRRRRRRSTMQYPEGKFPWIDRQIEAGNTKSDKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1E9</accession>
    <name>A0A1D2N1E9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1E9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="635" mass="69758" checksum="5DE74E5CFF284274" modified="2016-11-30" version="1" fragment="single">SRNSAKSRLDERKTKGPAPGPAKSRLIERKRKRPALGPASRKKNDLEKKKNERKNDTSASGSQRATIGGRRLRLIPKGKPVSTENSDKPGHGSDQNVKLTSKGTTRVAAVKARERMAPTKGSRKKIIIGRGRLASKAKVGEEKTTETKTTVEQSMRRTTTKRKLGENAVTDDDDGVDSDVNPVPPKKMKYSENSDHEDKSSRSLPVPKSKAPVKDQGKSKHQTSKMPLKNVQDSDDDIVATVSPPMSQSKAPVQNSMSTTQKSRTPPNNKAKSQQSAMKGESGDLKIIQSRKFKSRSSKSLEKTTVTQVRTTRSKTRLSECRNGMGNKKRLVIEIKKLTTDDLALWTHSKRETLQLHDSMDMETTELTTPQRSNSPVAPENGAEDGISPSFHNSSLDVSENDLDNANQSVHEPAHDATLDEYSRNVVSAVEDSVNMDDHSGGSEESEADHDNCEGDSVNMGDHNNDGSKVSEADHDNCEDDADFLEFGIEENEEAYNKLQNSDITQNKALIRASFSKNSATSIHPTLGDYKEEFSGVSRNVAEASADTHVGYTIIQPKTVKPLDMLTTPCIYWVLEGAVSVRSGGGTFSAKGNRTCMFSTTLKRRSCLYIPANTAFTIENWGSKKAMLGYSMHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Y9</accession>
    <name>A0A1D2N1Y9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HSPB1-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May play a role in cellular stress response.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000293">
        <property type="protein sequence ID" value="ODM99231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Y9"/>
    <dbReference type="STRING" id="48709.A0A1D2N1Y9"/>
    <dbReference type="OrthoDB" id="438164at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF43">
        <property type="entry name" value="HSPB1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="123"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="476" mass="54491" checksum="E1BF5F690BC7EE5B" modified="2016-11-30" version="1">MDDSSKILPLRSISGDPAAIGRNQFVSNKFAECLRELILKDKIGEPLVFRKIHEDWAPCKWTLGDWGDIFRDEKLSVRYGRQKWDKNTPQWESSCGNLEITWTKLIEWIRGEYNLPIPNSSPQDIWMYYDYKYLPEVIHLKSESEKDFLKLIYLSENLKKKFCWSNLGFHDRNGDHSTLWIGTSGSYTNTHYDTYSCNLVCQVYGKKTWLVFPPCDTEYLQPTRVPYEESSVYSQINVASSKQIQNNISAVKKCSPRRITLEPGDCLYLPPKWWHFVKSEDFSISVNTWIELPSDHFTRVEEAVLRAVVSSFVNSTVPSTADKVLNPNEMDLTEIGEKDTEDTLRLASKAFIDYENSISQSQSAEKSDKVSEPQVKKPKLSNEEISLEKLMEYSSVCVEKPSPFKLEVEALASCSETSSESSSSQLPSNVDCNHEAPPKGSPTYFEDVLNAVGHPDVLKQIAQRFLHNVKQRKSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N254</accession>
    <name>A0A1D2N254_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Serine/threonine-protein kinase TBK1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07303</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000285">
        <property type="protein sequence ID" value="ODM99377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N254"/>
    <dbReference type="STRING" id="48709.A0A1D2N254"/>
    <dbReference type="OMA" id="HECKRRI"/>
    <dbReference type="OrthoDB" id="10013850at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000100">
        <property type="entry name" value="inhibitor of nuclear factor kappa-B kinase subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051180">
        <property type="entry name" value="IKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041309">
        <property type="entry name" value="TBK1_CC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041087">
        <property type="entry name" value="TBK1_ULD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22969:SF15">
        <property type="entry name" value="FI05319P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22969">
        <property type="entry name" value="IKB KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18394">
        <property type="entry name" value="TBK1_CCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18396">
        <property type="entry name" value="TBK1_ULD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="12"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="667"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="775"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="701"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="776"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM99377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="807" mass="90981" checksum="2A0DF05E6906B7DD" modified="2016-11-30" version="1">MSYLRGSANYVWCTTSVLGKGATGAVFQGVSKHDGEPVAVKTFNQLSHMRPQEVQVRGAGWGGKVIVMELCTGGSLFNILDDPENTYGLAEDEFLLVLEHLSAGMKHLRDNSLVHRDLKPGNIMKFVAEDGRIIYKLTDFGAARELEEDQEFVSLYGTEEYLHPDMYERAVLRKPVGKTFGASVDLWSIGVTLYHVATGNLPFRPYGGRKNKEMMYFITTKKESGVISGIQTTENGPVEWKRELPNTCQISAGLKTLITPLLAGLMEVDPRKRWSFEDFFSAVLNILARQKVHVFFVNRIQSLRVYMDLAVQKDLNDFQSLVTDQTDISPENQILLFKETSVAKILDNGRKSSAAIPKTTEDMPLILCHRENNNVSLEWDTKDLPKFPAFPNLVNVENDASLAKHTCGVGYCYKRRVEKISRSVSLINQAVKTINQVIATELVTVTKEGSQTQSVIQSLHQQLNLMNQFQKACHSFLSAVPSLEKSINVKIDSMGQLVEVQQIEFKSMSGHLAELEQPVKQLHSRFVENNVLMAEWDEATSEIKDISRASIKAATHVGKLRESWQHLLRDRATRNLTYNDEQFHILERIKMQEKAKCLSELLNDECQHAIIRLTEVLSDWYKTAQAAFIQTEILAKDTYQFEESLELYLLRMKEVVTTYQTDLSNMTSGLKPYTPQKRALRTRSRERGMNGGVDLSDRENSIGNSGSLETTYHPSTRKSSNRKTTTTTSQREYVKTFNKGLKELTSVQEEVWTILKENAELVNQFQTLTLSLLSSDGSQGYESNPSSTRNSLSKNDSDLSGKSNGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2H2</accession>
    <name>A0A1D2N2H2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nephrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_07199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000278">
        <property type="protein sequence ID" value="ODM99483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2H2"/>
    <dbReference type="STRING" id="48709.A0A1D2N2H2"/>
    <dbReference type="OMA" id="WAAHETI"/>
    <dbReference type="OrthoDB" id="8825892at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF30">
        <property type="entry name" value="SIDESTEP VIII, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13895">
        <property type="entry name" value="Ig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="103"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="200"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="302"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="442"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM99483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="641" mass="71237" checksum="EFBF4D2A46434249" modified="2016-11-30" version="1" fragment="single">RPLDVKLLNKKAALSADKEYILECLSSGARPPAVMTWMRGSTKLQLKHHRESVSSNENVTTSIMTFVPSLEDSGKILACRAENPKIPGSMIEDGWKMDIHFVPQVNLDFGSKINSTHIREGEDVYFECSIKANPWIQKVSWRHNGRILHHNTSAGIIISNQSLVLQSITRKSAGLYTCVGTNSEGDGASNPVVLNVKYAPVCKSHQQTVYGIARQEQAKILCDVDANPDTDLQFRWKFNNSAETIDIQQSHFQVERHRSTLTYKPMTELDYGTVLCWAAHETIGMQKIPCVYHIIPAGKPDAVSNCSILNQTFDSLFVSCVEGFNGGLQQSFVIEIWDFHSQHVIRNLTNHRPVFNVRGLEPGASYIVRIYAVNTKGRSEVQVLQASTLKAAEKQTGYSAEASSVKPVFLNMTPILGILIAVVATLILVAIVIVLVMRGRGHTGEDKRVPKPNGGLKSSPEHDKSTVPLKKSVEEMPDVDDKNPDVVPHSSEIDGIDPDEKVFLERLNNTSRFYETIPRAVRTASRPDPNSSSELVNNVKNRVPRTGREEVTYAELSLPNSPAYHPGTLRHQPIRPQEPIIYAQIDPLKTAQCVPVGVHEQQTQTLPGYPLNLPPHPSSEVETISWKTIRSSLPLLKESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N326</accession>
    <name>A0A1D2N326_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UMP-CMP kinase</fullName>
            <ecNumber evidence="9">2.7.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Deoxycytidylate kinase</fullName>
            <shortName evidence="9">CK</shortName>
            <shortName evidence="9">dCMP kinase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Uridine monophosphate/cytidine monophosphate kinase</fullName>
            <shortName evidence="9">UMP/CMP kinase</shortName>
            <shortName evidence="9">UMP/CMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07042</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>CMP + ATP = CDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UMP + ATP = UDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>dCMP + ATP = dCDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.14" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000266">
        <property type="protein sequence ID" value="ODM99640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N326"/>
    <dbReference type="STRING" id="48709.A0A1D2N326"/>
    <dbReference type="OMA" id="EQTMPVI"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000315">
        <property type="entry name" value="Adenylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03172">
        <property type="entry name" value="Adenylate_kinase_UMP_CMP_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006266">
        <property type="entry name" value="UMP_CMP_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01359">
        <property type="entry name" value="UMP_CMP_kin_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="9">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="64"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>CMP</name>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM99640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="21784" checksum="2FB47ED47290294C" modified="2016-11-30" version="1">MSASKPNVVFVLGGPGAGKGTQCANIVKTFGFVHLSAGDLLREERSKPGSEFGELIEKHIRDGTIVPVEITCSLLENAMTKNEKNNFLIDGFPRNQDNLDGWTRQMGDKVNVHFVLFLEAPEDICVNRCLSRGQAGSGRSDDNPESLKKRVVTYNNDTMPIISHFDKLSLVRKVDAAKGTEEVFDQVKEHFKGFVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N414</accession>
    <name>A0A1D2N414_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sedoheptulokinase</fullName>
            <ecNumber evidence="10">2.7.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Carbohydrate kinase-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_06665</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a modulator of macrophage activation through control of glucose metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>sedoheptulose + ATP = D-sedoheptulose 7-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16802"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.14" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000238">
        <property type="protein sequence ID" value="ODN00013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N414"/>
    <dbReference type="STRING" id="48709.A0A1D2N414"/>
    <dbReference type="OrthoDB" id="10264182at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050277">
        <property type="term" value="F:sedoheptulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071396">
        <property type="term" value="P:cellular response to lipid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901701">
        <property type="term" value="P:cellular response to oxygen-containing compound"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006163">
        <property type="term" value="P:purine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009617">
        <property type="term" value="P:response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07777">
        <property type="entry name" value="ASKHA_NBD_FGGY_SHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000111">
        <property type="entry name" value="Sedoheptulokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000132">
        <property type="entry name" value="Sedoheptulokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF67">
        <property type="entry name" value="SEDOHEPTULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904996" description="Sedoheptulokinase" evidence="14">
        <location>
            <begin position="22"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="15">
        <location>
            <begin position="374"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00052736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00057196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00066341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00069425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00076706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN00013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="805" mass="88831" checksum="C885EAB002589545" modified="2016-11-30" version="1">MQSVYLLSVVILVSTVGTCLGQANLTCQPGLVQPVVNFTFDSYLGTWYAQKVYARLSEDAWPLEFRCLEVTPIRRHFLAEERFITYPNGTDIRTVALAYGHFSEQTEAIWNLVSFWDGELSEGNSVIVQTDFENWSIQFICKVTEHYKYETMFILTRERNADPDLLALLEVVVKNYGFAAENGSNTIMANWKYAVSIFIAAFLISSFCSSGCAASVLKQRFENNDFIYIGNMSSDSVENKAGTKSLSLYLSGPNDRKETQIAAAHQCRSLEGTLLYILNTVQFEEVKLAIHGLGEPFWTAGVYDGNLRSFVWLTNNREVNRDFIRGESRCSEANTLMGLTVQGSLSAYGLCGTRTESGLRYISNVPSECGTEGNKQDVPKICSTVHSVVTRLPRELLKRVVYIGVCGQMHGIVFWKSGQGWERNGDKIEPRVTSNLYTWQDSRCTKDFLSSLPTPDSHLSVNTGYGCATLFWMARNKPEKIEKFDRAATIQDFLVAMLCDLDEPVMSVQNAASWGYFNTEKKEWNKDILEAAGFPIRFLPKIEMGGHYAGRCSATAWLVVSEGTPVGAAMGDLQCSVSSTLARVDQAVLNISTSAQLTFVMPTGFHPKTALEEKSDETGNGCGICGDEESHVQYYPYFDGKYLAVAAAMTGGNSLAAFVRMLQNWAVTLGCNVPQSKIWEKLLAASANAEATSSSIEIIPTIFGERHAPEQNASVHNIDLGNISLGQVFRALCRGVIENLHRMMPSSMLTRAGVTSVIGSGSALSRNLTLQQEFLRIYNIESTFGKGGDAAFGAALAVLPNLQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4L7</accession>
    <name>A0A1D2N4L7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">Ocin01_06672</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000239">
        <property type="protein sequence ID" value="ODN00005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4L7"/>
    <dbReference type="STRING" id="48709.A0A1D2N4L7"/>
    <dbReference type="OMA" id="CQFFKFG"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF40">
        <property type="entry name" value="INNEXIN SHAKING-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="347" mass="41274" checksum="EBC5C283C54D32FB" modified="2016-11-30" version="1">MLDIFRGLKNLVKVSHVRIDSSIFRLHYSLTVMILLAFSLIVTTRQYVGNPIDCIHTKDIPEDVLNTYCWITHTYLVISSFHKQVGRDVPHFGVDKMPTDESDMKVYKYYQWVCFCLFFQAILFYIPRWLWKNWEGGKIQALMMDLDVGIIPDMEKKQKKKLLVDYLHDNIRQHNWWAYRYFFCELLALGNVIGQMFLMDKFFEGEFLTFGIKVLRLSEEDEERRVDPMVKIFPRMTKCIFRKGGPSMNIETHDALCILPLNVVNEKIYIFLWFWFLVLGFLSALTICYRFVVFVSPRIRGFILGSRFRLLSQDVIQTLVKKSRLGDWFLFYMLGQNIDSIIFKILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5D5</accession>
    <name>A0A1D2N5D5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000205">
        <property type="protein sequence ID" value="ODN00483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5D5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="190" mass="20825" checksum="AAABD5272DADCE9C" modified="2016-11-30" version="1">MTDDPEKIKVITMDKKGSFPSSFATNTNKSLALDNSAKTTAYSRQDGTSGSQISKVQPKTPTRYRGNQTSNTGGFSRNEAYNRYKPTPQKGKYADRKPKPKGGQSASESVAQKETEPEGATSHPPGGKKQNIKDQDLDLWGFQYAPLQSHGYVHGHLQRRSRPSSGGPSRSNYGAGPIRPKYSKDYLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6S7</accession>
    <name>A0A1D2N6S7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein HOTHEAD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000179">
        <property type="protein sequence ID" value="ODN00973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6S7"/>
    <dbReference type="STRING" id="48709.A0A1D2N6S7"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="11655" checksum="01D7C0820D6138F4" modified="2016-11-30" version="1">MNAVTFTRGGLGTTQSALRYGSIIYTIVSLMSPGFHFFTEMDRNMDLMNMPSQNNDDTFDFIIVGAGSAGSSLASRLSERFSVLVLEAGAAPSPIHSVPTYAFGNFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Y0</accession>
    <name>A0A1D2N6Y0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquinone biosynthesis protein COQ9, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000176">
        <property type="protein sequence ID" value="ODN01014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Y0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905135" evidence="1">
        <location>
            <begin position="19"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="11576" checksum="2C33E501FE0A003E" modified="2016-11-30" version="1">MNTLSVAVFAAVCAFASAGLLGAPVAQVAYAQLATYSNYGARISQSARPVAYAQVAQSVAVPAATYSTFKNRVSQSARPIAYAQAVPQIAYAQQAIAAPVAVAHAAPALGYGSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Y1</accession>
    <name>A0A1D2N6Y1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxisomal membrane protein PEX13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000176">
        <property type="protein sequence ID" value="ODN01007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Y1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905129" evidence="1">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="10800" checksum="7AA76DAD3C0417F8" modified="2016-11-30" version="1">MKSIVAIALLAFVACANAGVLGHPVYHGPAIYHHAPIVKAVHHHPLYAVPPPILAKPIVYAPAPVVKVFHPAPVVKHVSFGPVAYGHAYGAYGAYGLHGPAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7J8</accession>
    <name>A0A1D2N7J8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light chain roadblock</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05461</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000166">
        <property type="protein sequence ID" value="ODN01234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7J8"/>
    <dbReference type="STRING" id="48709.A0A1D2N7J8"/>
    <dbReference type="OMA" id="NNSTIEY"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000009">
        <property type="entry name" value="Dynein light chain roadblock"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016561">
        <property type="entry name" value="DYNLRB1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009998">
        <property type="entry name" value="DLC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 10" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="11">
        <location>
            <begin position="13"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="106" mass="12060" checksum="6B1D4B84CD0EA033" modified="2016-11-30" version="1">MSRYPKYSESNEVEEAIKRILSHKGVVGLVVINHEGIPIKSTMENALSVQYAAQVTQLLDKSRSMIKELDSNNDLTFIRLRTKKHEVLVCPEKDYAMIVIQNPTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N882</accession>
    <name>A0A1D2N882_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PEST proteolytic signal-containing nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05181</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in cell cycle regulation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with UHRF2/NIRF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000149">
        <property type="protein sequence ID" value="ODN01480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N882"/>
    <dbReference type="STRING" id="48709.A0A1D2N882"/>
    <dbReference type="OMA" id="MPPECKM"/>
    <dbReference type="OrthoDB" id="10068198at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029169">
        <property type="entry name" value="PCNP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16523">
        <property type="entry name" value="PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16523:SF6">
        <property type="entry name" value="PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15473">
        <property type="entry name" value="PCNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="256"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="35451" checksum="99A7B94757393B98" modified="2016-11-30" version="1">MHDYNEPRRRSHRDDEDNYAAKKPRSRWDETKRHEGEKPRSSRWDDSSGRSSHQNSKSRWDEKESSSSNVEKSGSRWDNNGRSDAGKSGSSQSRSRDRRSRSRSNSPFRRDDRNYSNYSNPSKDEKSGADSKTIPSSLVNHQIAKKYSSWSDSSSDEERGSRKLDKNKHDTGNSYSEFGHSGLPNSLRSNISATDVMLSRGAHSQGLESHEVKSNTGTAPGISLKLGGTSAKPAMPLPKVISVSVPVKAAKVASIFNDDDDEPEEMPPECKMRMKNVGRETKTSEGPNSFGKTKIGFCNLSHLAEKKLDGKMEAKKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8M7</accession>
    <name>A0A1D2N8M7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-binding protein RFX2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8M7"/>
    <dbReference type="STRING" id="48709.A0A1D2N8M7"/>
    <dbReference type="OrthoDB" id="10056949at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000017">
        <property type="entry name" value="transcription factor RFX3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039779">
        <property type="entry name" value="RFX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057321">
        <property type="entry name" value="RFX1-4/6/8-like_BCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619">
        <property type="entry name" value="RFX TRANSCRIPTION FACTOR FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619:SF33">
        <property type="entry name" value="RFX, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25340">
        <property type="entry name" value="BCD_RFX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02257">
        <property type="entry name" value="RFX_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="RFX-type winged-helix" evidence="9">
        <location>
            <begin position="623"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="315"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="482"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="509"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="543"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1141" mass="127569" checksum="E1709065790BCF75" modified="2016-11-30" version="1">MLKLHPSHKYFDTESGSFYYEASDDECHHKQMVEEAKSFDSILWCVATICQQGLYQTPKSFSVRIILICGYLLSVICYAAYTGMIVSDLWEVKHPLKSLRQLLDYTDKIYLITSSDTTSVDLEVFSKNDPKLGNKLELKGFNEVFSELTKKPAKTCVLSWMDYLTNIAEQVLSKHEGTSQTKYARNIHSRVNEFVCRTFSSFQFQKLSYMYVPKNSELEKLFNFRIIIGLERGFIRRYWNEYKRNTEPPCLQTNAQMTPMDIGDVYLCFVILLAGMATSLLIIMPPPRHKGRRTSPRFQNQQQVYTSVSVAQVKQEVLSPKTPPTSKETKGKDGNLLSTPKGLTSPAFTGMHGLQNSMMDTTSPPIFSMDAITDVLGEMVGSDSQEDDNVKLYGSSASFLNDISTIEEQADSVATALFNASKRGTSTAAGSSSMRFHNESSAAASSDLASSSLPQIEHSLLESFMSPQNSSRCSSPIYSRVQDPLEDEDGNGRGDGDGSSSSNNVSDCSDSDFELEDDSSPPSDDSSDSDFNLEDSDSEYGAKKRRGGAGRKRGGAAGNKQFGAQIIPGLCHRQNRRSYHHQKSSKSKEQVVLLMGSDQPLHKPINSHQLEAIAATMGSSPVTVNWLLQNYETSEGNSLPRALMYGHYLRHCAELRLDPVNAASFGKLIRSVFVGLTTRRLGTRGNSKYHYCGIRIKDTSTLLLEDPDLSKKTRTNGKRSKKTQILAMQGGICGLGSNKGLQLEIGSSGEIDFNSVKKYLGSRCASFPEIAVSEFYLPDGVSYQDMLYFAEVYRKHCVEILEAAELFKLGTQLEKIWYQFWQRDRSYDGFHAHGSGITKESLVALTKVPEIQFAIQNLDAFTYDQVLSVLMPNVIAQLPFQLLEEYHKLTLTIQQWLTSSLGSYDPEFVQQKTELIVSFKRELETWVSLNLSAHSARDSMQSPNSIAQLLSDLNRINFRSVLMDVKEYVNVDEMDINVHESLKRILSGPDSIEPWSVWLVGLVDQRLGMSSTVRAAQDGHSTVNAVVKECQDLSLRWLKYMSQLKLELLLRSSGSLATFLSLELLFSNFLLHLIKVYKSRALQVPLVMYSVVRNTKVKECVNINNTGLDSHIPGVSIPQGQNEVSQVTIKKEIVDNGDEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8S0</accession>
    <name>A0A1D2N8S0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein KTI12 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05298</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000155">
        <property type="protein sequence ID" value="ODN01376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8S0"/>
    <dbReference type="STRING" id="48709.A0A1D2N8S0"/>
    <dbReference type="OMA" id="THSRWDK"/>
    <dbReference type="OrthoDB" id="419889at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000827">
        <property type="entry name" value="KTI12 chromatin-associated homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905223" description="Protein KTI12 homolog" evidence="5">
        <location>
            <begin position="17"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN01376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="301" mass="34662" checksum="A36397019ACFCDE4" modified="2016-11-30" version="1">MFEVKVLLFVFQSTVYFKMPLVVMCGYPSSGKSTWTKKLAEYLEKEQGKQVHVVKEEEQFRGEKNDILDDSRKEKELRAKVKSESQRLLTKDNVVIMDALNYIKGYRYELFCISKAVPTRQVTVHCDVSEAQAWEWNINTDRPDNEKYTREVFEHLVQRFETPDPQNRWDSPFFSVLSGEELDLQGINTSLFFNKTPKKNMSTQSNPVTESNYLGTMEKVTSEIIQKIIAAGTERDSGTVDDIQEVEVPYSKLTVHVEDSLTVSQLNKLKRQFITMCKTSSLKGEPGDMFVQYLNSQLSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAV0</accession>
    <name>A0A1D2NAV0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04546</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the globin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000124">
        <property type="protein sequence ID" value="ODN02116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAV0"/>
    <dbReference type="STRING" id="48709.A0A1D2NAV0"/>
    <dbReference type="OMA" id="WKQLFTF"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005833">
        <property type="term" value="C:hemoglobin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01040">
        <property type="entry name" value="Mb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002336">
        <property type="entry name" value="Erythrocruorin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044399">
        <property type="entry name" value="Mb-like_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47217">
        <property type="entry name" value="GLOBIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47217:SF1">
        <property type="entry name" value="GLOBIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00611">
        <property type="entry name" value="ERYTHCRUORIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Globin" evidence="7">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN02116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="17258" checksum="61C9191B6189E6B2" modified="2016-11-30" version="1">MLSSTEEKVIQDTWALISPDLKKSGVGVFLRFFTDYPNYQKSFRSFANVPFDDLPQNKRFQAHAYTVMNAIDGMVNNLDDPEMLDEMLLRTGVNHGKRKLTGQAFDEFKSSFMGYLETTLKDKWSSETEAAWELVVALIITKIKDGMEAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBB5</accession>
    <name>A0A1D2NBB5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclease domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBB5"/>
    <dbReference type="STRING" id="48709.A0A1D2NBB5"/>
    <dbReference type="OrthoDB" id="9989103at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050621">
        <property type="entry name" value="Tudor_domain_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948:SF29">
        <property type="entry name" value="FI02030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948">
        <property type="entry name" value="TUDOR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="2">
        <location>
            <begin position="241"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="393" mass="44018" checksum="C8EF0DBD664FDFD1" modified="2016-11-30" version="1">MSFSRASSGMRLLNTPDNCGSIKGIPCKNVRCDQEILCVNNEDYYCSRDCYSIKLEREQIEVDTTAVKFKRRTIIGRGGTGLLNDRGALDRLIIRVDSQFGRTVTSHKGSIGGVQKKSKKKGQPLDPEELLRKQKKEEDKRRLRELLNNDVDAGSSDETTSSSDDDLDEAQSSAVNSVICPPHPPLVTEEGKLLKAYVVNIVSPWEIHIQTGKMIQKTGEIEAICNRVEGLDPRLVDENWSPQVGGVCCAKFEDKMYRAKILEKDGNTFRVLYIDYGNKELVPCIELHQLNPEVTLIPAQCIFFRLSNVKPKTHWENDAGNSDVIKFTVEHLEGAVVGLHIDAVERNEVHVGKLKIISSLSGLIEGDFGEALVKRNLADPDSYYLEELKNLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBJ5</accession>
    <name>A0A1D2NBJ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rab11 family-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Recycling endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000104">
        <property type="protein sequence ID" value="ODN02611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBJ5"/>
    <dbReference type="STRING" id="48709.A0A1D2NBJ5"/>
    <dbReference type="OMA" id="IPEQGNT"/>
    <dbReference type="OrthoDB" id="8956628at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045055">
        <property type="term" value="P:regulated exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037245">
        <property type="entry name" value="FIP-RBD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037789">
        <property type="entry name" value="FIP_classI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019018">
        <property type="entry name" value="Rab-bd_FIP-RBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15746:SF23">
        <property type="entry name" value="RAB11 INTERACTING PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15746">
        <property type="entry name" value="RAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09457">
        <property type="entry name" value="RBD-FIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144270">
        <property type="entry name" value="Eferin C-derminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51511">
        <property type="entry name" value="FIP_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="FIP-RBD" evidence="8">
        <location>
            <begin position="496"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="580" mass="64932" checksum="4443B34BA65CA3AA" modified="2016-11-30" version="1">MLQRAKGLLLKGKNGTNDAFVTISLGKEKYQTSVKERTTDSVEWHEECELAIPRHGNKAEIVLTVLHRNFIGDEFLGQISIPLSDFDVYDKPKNRWYNLKCKPGQDKTNYRGEIDVRVSFTVQSGVTAAGSLTELKKDGIRASFGQLSQKVGSSIGGSLLSLKGKDKKGLKSFAKAVGNKVSTLPGRGHKKRHDDNFGAIPEQQTYTNNATNLNQKHAANESDPGVISDDEDEFRFDELSHKSSHSSLSVSQVALSSPRDGSLENLGGGEFLRRNYATPPPVKPKRASEPPPEKPERWSTGPIDDWETKLFGKQNMLDKASSLKSVGRNSVGSSNGYPSEKEEIKVNDEKEEDKQSLKSESPLKPTFQSIFTVPSKEKEPVPKPRQSPVVTKPEKETKPPPVVEEPPKPSPKPVKVEKVSKVEKVAKQEKSIKVEKAIKAEKESREPEKPVNGVAKEAPIPTIVTPTRNVEDEVPNQKWTPVGITNPIRQKDSHQETRLPREILKKFENKSREDLIELIMKQQTTLEYQKHKLNDMEDYIDNLLVRVMEVKPTLLQTPYVTNRPMKLSAEHNGDWFSLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBW2</accession>
    <name>A0A1D2NBW2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 13A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03950</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000097">
        <property type="protein sequence ID" value="ODN02737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NBW2"/>
    <dbReference type="OMA" id="SGWRPIR"/>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056748">
        <property type="entry name" value="VPS13-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056747">
        <property type="entry name" value="VPS13-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25037">
        <property type="entry name" value="VPS13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25033">
        <property type="entry name" value="VPS13_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="VPS13-like middle region" evidence="6">
        <location>
            <begin position="1086"/>
            <end position="1922"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="7">
        <location>
            <begin position="2009"/>
            <end position="2548"/>
        </location>
    </feature>
    <feature type="domain" description="Intermembrane lipid transfer protein VPS13-like C-terminal" evidence="8">
        <location>
            <begin position="3133"/>
            <end position="3246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1014"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1364"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1575"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1024"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1382"/>
            <end position="1393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="3303" mass="371789" checksum="615CC77BCD76D54A" modified="2016-11-30" version="1">MVFESIVVDLLNRLLGDYFENLDTSQLKLGIWGGDVVLRDLLLRNSALDDLNVPFKIVVGKLGSLTVKIPWQSLYTAPVELKLTDLLLLVAPSYSVKYDAVAEEKAAQFAKKKEIERIDDIRRKEQAKKEDPKPQADDTFTEKLITQIIKNVQIKIETIHFRYEDDVTKPHSPFGFGVILKNLELQTTDGEWNPAVVTEAAQTFNKLATLEGLSVYWNSRSELLQSNRSSAEMLKLLRDYVVSNNIEVTHVLGPINSTAKLTLTPSPDRGAEPFSKPKFMIDVLMQELALGMTNLQFQDIIELAESIDFMFRAQLYRKYRPAIKEHGGHYKAWWKYAYQCIIEEDVRRRRNNWDWNHMKWHRNLCKTYANVYYQKLTQLKLKAELINTINHCEMELDLFNITLVRKQVEMRIEKEGKRKEQEKQTGGGGWLSGWGWFQGNASPESTDLTVNAILGKVEEALTPAEKSKLYSAIDYTENALPLDYPQEYLEYCLSFTLKKLSTTVREFGGRGRERKGHTILQLEIDDVETQVMTRPVKNGMQVIVSMASLNAVGMQTRPDVPAPVIVESKITKGETNLFHVQFEANPLNCNANQRIVVRGNPIEVVYDGKTVSELVNCFTLPSDAKLTRLQAAAVSTINDWKEQSTAGLQYLLDTRAEKEVDIHLIAPYFLVPQGGLLVPDISVLVMDLGEISVKSKPREKNWNKEKISSFKKSFETEEQFLKAMMKIAYDTFIIELRDFQIFISLPDEDYVAAVSKTQPTGKKLLPKTLIHANKFIVTLEQLLIPEDPRFPRLQIQASLPLLGFDITEDRLVELLKLLVTLPFPHAEEQATPSLSVISESTAVAESYAISKITYSDAALEKKEKKLVEIVEMLIRFTVDAVKIRLTRMGSRNDAEVPFADFEMNHLQLRLKSKSYSSSIDVGIGGLTLCALQNTIPNHDGPLYLLKTPMSEGSETYLLKMHMFSIMPNCPPQFAGKVKQSIKADISSLDVILHQEAISSVLGLLEKVTKTLEESVEKNRPLNPETISLQSTSSTESRRKARSNTQVSRLEARRRAVAKKHKDPNDVLLQIDAKMESLTVQMSYENKNLIKAVLSSMDFSMLHKTGKMSICLELTNLSVKNLDPHSLYKDIITVNEDRVVYIKIMMFDEGSKGRHFFDMDRHDMSVRIETGSPKIIYLNPFLDEVLNFLFTFGTTREAMLEASAAAAAAAKESVEQSVAGASRILLDISLKAPLVIIPRNEKSPHAMLADLGHLTLKNHFEKRKVGEAETYIIVDRMEINLMNVKVSRVFFNKTIQQYKSEVLMLEPVNCKFWIDRNLSADAYHGMPDMVVKGTIRAATMRMSNEDYDLMLGCVLENIVVSPPSDGNAAAKGSQSGKRKSKVKSVDVEKKESDGSMRTLVSAPSMASSKAEVYINMQTYLMIPQLKFVMYEKGVVNLETNDGVVERDEATAFASIAVQNVSLNFESFNNGNTICPIVIENVSLLDIRPGPRAIKSLIHRKLDDKTTGGGPIVNFNYKFAENSGATMELETTSLTLVLALDYLMKILAFFQTSGPSPEIPKQDVTLRLEPTSVLPTDPVPAREITAGKPGVTEREDSPSSEMWNAFYNFSSTEIILVETMERIDTKALLLNCEVVFKQTDADGKSNIMGTISNLKLNSCIYNPTLRESSSAEVISPMSITVVWNSSQTTGSLIDVNISNIFVRLTAGTVELLVKIFGSIGATKIDENALIEKVNYSDIWDVKDANKLDLWFLRPEAWYEVAQDALALEDKQPMGYEYAMDLEPNERLVLESGAIVFTFETGTGNITMPMLLVETDIDLQVFDWSRNMKVAGRMKLEAAYYNAMFGLWEFLIEPVETRHHGRVAHQPWEVLFEYAYGPANSSPDSTPTNLPNPKTTSMLLQSNDVLELTVTKTALNTISMISEDFSSAVKELVSRREVSTAPYSIVNNTGMDIKLYLKEKGKPGPFILIKNGMEYEEVILKHGTFINLGLVEETDLTKHHTSVLREQEGRADRLLTVEIPQEEFKNSIPVNRSAKRYFPFKANVDHGHYGMICDIGVRDCSKIVTLRGVVQVVNDLEVPVDIYYMADGGKTAKLAGTALQQNVFNLPIPCTYTESCNLFFAPEGYSVTTQPFRWDDVFREIQVVKQLSCCFRKAGHDDFHIRVVGVAKQALHECSNRKNIASQCCFIYLKPPVKLDNLLPVPIGYYVDQKQHRIKMADRGCAIQVTNLITGKDEEYHLYLKIPDYKRQSWRCDVIITKYTEEVSSWLFISDDNVHESLTLGIHRELSNDEIILHLYCPFWMINRTGLSLIYKGDGRDSPQTTHLRDVGDKPIMFSFSGKGFFSKKSANVKVQDGHITTPSMTTDWSEKFSLDAAGSCGSVTCKSPMQNFQIGVEIQLSGWGLTRYVIFTPRFYLANQCPYSVYVVEEERPDGESEVPAGKCIPFWPKSQVPNLKAVVKILKRRDETAAFRYDVVEHTLLQLSNEYGGLHVDICLTESKTSILFDQFVPSQAPVLLINKNKVLGIELSEKESHENFHLGPGKCQYFTWKNPLGSRMLEWWPAGKKDSRKHRQQNNLLMDGFGTFEVERKGEKTDQFWISFLDGSQRYLMFVDDSSIVQMLQTREVEVATAEYTVTLHGLGLSLVDNENLKEVMYMRIASSDIVWEQCKDGKRKRYKPLQIDDSKAVEAAYQNYLNHKAISKTVKSLIQLDSGLEVDFYVMRVIKPQAATIRRVFQTGIWISYKTLPHSTQLHAKLNRIQIDNQLTDGIFRVVLAPVKPPKTISSIDASPKPFVEISIMQRTSSHSYVVQYKYFKVLIQEFLVRLDIGFVNALVELFGGNSTVADEWKDRYLKEYDEVCTALDEFLARQIVQQGQKHFYDYLHFSPLKIHLSFSMVGSTNISNHLLKLIIASLGVTLTEIQDVIFKLACFELHHTFLSSDQLQDEVYSHYWSQGVRQLYVIVFGLDVIGNPYGLAMGVAKGVEAFFYEPFQGAIQGPGEFAEGVALGVKSLLGGTIGGTAGAFSKITGTLGKGIAALTFDDDYQKKRRENLQNRGDAAEGFARSGKGLVMGFYEGLTGIVTKPVEGCKEGGAAGFFKGAFKGTVGLVARPAAGVVDFASGSFDAVKKATSATEDVRRLRPPRYIPADTILQPYICHEAEGVQLLNELEKGKYSNTDNYVAHALINPHGIYVLLVTNRRVLYLKRDELFGTWATEWNHIWEEFSCPPEIVERGLLFTLKQELVKKIVLFRIGKSKQLLVPIYSAEVATRSNSYISQWLVSKIEEAMRTETGMTWNDDAGGGGSGGDAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF89</accession>
    <name>A0A1D2NF89_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monocarboxylate transporter 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF89"/>
    <dbReference type="STRING" id="48709.A0A1D2NF89"/>
    <dbReference type="OrthoDB" id="5667at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008028">
        <property type="term" value="F:monocarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF306">
        <property type="entry name" value="RE01051P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="615"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="661" mass="72260" checksum="20B569B1378A657B" modified="2016-11-30" version="1">MTCIGPSTLTSFGLLTIDLPISPTNQSWLLVLLYGFWQASAILASLYAKESPRQLATLGSALAAIGFLISASFVEDPSWLYLTFSIFIGFGLGLSFHTAYLVVMSNFERYKGLANGICQLSIAIGQITTPLLYSVVSMPKDRFQIKALTTAVGFLTTLFFVVPNHTVPRRPSTVVNRNRRYSTASRRSSYGEAVPLQVGINPVSSNSYPINQGQMRPRRRSQYLLAVSTSLLPNIPEEPESSNSINETLASTSSESDIPTLQQTLASQSVAVLPCGNNDNSSTVNNSIQKTEGDNDVTTTEGEEDGVTKESENEFQVFTLHAAVRRKSEGCLPSYVGNFSEVNNKVGNGTATPVPNDKKTENKSVAQLNRQNSESQSKLRQSNSSIVVGKQLNINNIMRQSSSTKTAKQGESTIDLSLLSDFHFCNMAAFSALCTVSVVNFPLVLYAYVISFCEECKEEANTAVLIIYVADLISRLVISYLSDYQLLRRRTAFLIACSFAGLLVAATTLVKDISLIYCFSVLYGLCLATLVSSEYLMFIESFGFDRFPQAYGIINIFKIIVAAALGAFIGNPLSIYLYPIHPLDLKADDRNASLFCDPLDLFDSNQPTSSSMTRLLLNVAVPSILCAVAWIMEDIYKASHKCSEQTTKTQISSNANNSEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFK4</accession>
    <name>A0A1D2NFK4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease P protein subunit p38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFK4"/>
    <dbReference type="STRING" id="48709.A0A1D2NFK4"/>
    <dbReference type="OrthoDB" id="20109at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001650">
        <property type="term" value="C:fibrillar center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042848">
        <property type="entry name" value="Rpp38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46948">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46948:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="2">
        <location>
            <begin position="117"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="31933" checksum="B350E326CE037021" modified="2016-11-30" version="1">MTSHVKKLSAKKQKLSLGEVTKAEKAKAAANRKIIRATVVNPNDVEWPSLSDEDEQELLSCLTTDLQCLRFPNYHVPLSEIKKVEKGDRRKFRHIWHTERALEVGFDVAAYTKLRADISLGVNCVSTALEQNVLIAVIIEKDVDPPIITKLLVPLATSKEVPIVAISGLNQICQKVFNTRCIALGLKASFSCSLVCCNAKCSEVGHAFSQVFHVIQSISEKKLASANQEYSILYIPNIQVPPTPASSDPEVSQKQVVDAMDTTTTQNKKPRPSTTSSPADSFNPPKIRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFL5</accession>
    <name>A0A1D2NFL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prestin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02668</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFL5"/>
    <dbReference type="STRING" id="48709.A0A1D2NFL5"/>
    <dbReference type="OMA" id="FAAMENY"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="564"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="619"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="780" mass="86049" checksum="5F9463ACE0365C78" modified="2016-11-30" version="1">MRARHLPHSAADEEEEDDGEEHEQIRLVETPDPVAFPTMDDGKNIQTVGDLYNGKFTNSNGNHFHNGNSFTSASGQNGYPQYFSSKENNAGSFKSDLHKIFANKCKCTPLKWIIALIPILSWLPKYDWKSDLAFDMAAGFTVAVMHIPQGMAYAMLSNVEPIVGLYMAFYPVIMYSILGTSRHVSMGTFAVVCLMSGKVASERVTHYSTVPVVLTAMGNISNTTALNDTTNYSSYSTNEIVTVVSICVGVWQVIPKRNTGPCEKPEAYHASITYIHYVFESQILIGVFQLGSLSVLLSAELISGFTTGSAVHVFTSQLKNLFGIEMKRRSGIFKIPLTYWDTVLGIKAANITAVLLSCVTISLLILYNEFLKPMLNKRIPFPIPIELITIIVGTLVSRYWITSDKYGISIVNHIPTGLPDAKLPPLELVPDVLVDSLIIAVVAYAISISMAKIFASKHQYKVGPNQELLANGTSNIFGSFFGCAPISASLSRSLIQEQIGGKTQLAGLFSCSIILLVLLWLGPFFVTLPHCILSSLIIVALKGMFMQIADLPKAWKESRINGSIWLVTFLATVFLDIEYGLLIGVLITVASLLWKSNAFIITEVGQDVHSHMFVEKTSVSNMMADVNDVKILKLTGNLNFSTAETFTSEVNNILDSNLTYLQRKRSLELSSGKKLKTSAARSQQTFSASTIILDFSSVSTIDPAGLKAVREQHDKQAKQGVEILYVGCPSSVFHVMQHCKFLKYIGIQYFFPNIDYAVSYVKRKGRSIADQELIEIFPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHP6</accession>
    <name>A0A1D2NHP6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Proteasome assembly chaperone 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHP6"/>
    <dbReference type="STRING" id="48709.A0A1D2NHP6"/>
    <dbReference type="OMA" id="CCHLSSK"/>
    <dbReference type="OrthoDB" id="368507at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032157">
        <property type="entry name" value="PAC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33559">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33559:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16093">
        <property type="entry name" value="PAC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0647">Proteasome</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="17062" checksum="FCCEAFAEA8E41A46" modified="2016-11-30" version="1">MATTVDLELIERATSVLQISKEAGIESTDKLAASGSSTIKFHQFGTQVLDTTYFFQVTNFGNSIYLWIGDGSGKMDDLAMSSVTPYDKKGMPTTTKILGSSGDNLSESFAGKLTKRLKKPVYVSFNVDVGAMYTTILQDIEQRLYEEITLCPDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHR9</accession>
    <name>A0A1D2NHR9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lysosome membrane protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHR9"/>
    <dbReference type="STRING" id="48709.A0A1D2NHR9"/>
    <dbReference type="OMA" id="FNISDIM"/>
    <dbReference type="OrthoDB" id="195015at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF51">
        <property type="entry name" value="LYSOSOME MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="646" mass="73174" checksum="B1FECF98C5DDDE95" modified="2016-11-30" version="1">MKKYISPFLLFFGVVTFGVSVFVGYYVVPYKVRENVMEQSKIVMGNTRFQNWEVIPIPLFQHLYFFNVTNPNEVVQGGKPILQEIGPYVYQQKRRKFDIVFNDQNDTIFYREKADYFFRLDLSKGSESDRITFVNLPLVGTANKALKLDSFTRYVISETVAEHPEEQLYVNLEIGELTFKGKYLPFMKDLSELKGEEVLPDNTFGLYYKKNGTDQGRFEIYSGAKRPEKFGEVVTWNGKHELEWWNDQYCNRINGTDGGIFKPYATKDRIFQMFIPGLCRSFRFTFESEKEVEGIPTIKYSIAPSFFESAKTNPDNACYCEDPEKDFKNCPESGVTDLSNCGKVGMMLSQPHFYQGSDYYVNQSVGLHPEKARHEMALYIEPYTGVSAKVHVRFQMNVQLTPNKYFRPLKKIPRMVHPLFWVDQSVQVPEESLAVLREKLYGTINTANTLTHIGIIVGCVLIILSLLFFFLCSRDVAVEDKKIECVSYQPQRTFSAEKLSLAVNGVANGGPRYTKEPTKSYNPDECVQLLTQNGNLPQHTSQPQENQTSLFEAASPEPDDIIVVPASPIVVAIDGGNIPLPQVASTPQSQPEQAAAVLRDSIRTPDSCLSPFPTVTDYSSALSLADPISANALKDTIEAMSSYENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHX2</accession>
    <name>A0A1D2NHX2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BTB/POZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01872</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHX2"/>
    <dbReference type="STRING" id="48709.A0A1D2NHX2"/>
    <dbReference type="OrthoDB" id="636773at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022008">
        <property type="term" value="P:neurogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.820">
        <property type="entry name" value="PHR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012983">
        <property type="entry name" value="PHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038648">
        <property type="entry name" value="PHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774:SF3">
        <property type="entry name" value="BTB (POZ) DOMAIN-CONTAINING 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08005">
        <property type="entry name" value="PHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="143"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="597" mass="66369" checksum="C9EA3564C9263654" modified="2016-11-30" version="1">MEPASGRNASSSSNSNTSNTTNSSNSRAPSSSSGSSSGGGGSSKNQTVVTVIIPPNMSASSSSGLKVDSSSSSNKSMEKSFPPSSAASSPCAKKRKLNLRGEKEGQNLIPSSTLKSAVVHSWQETKASIKERTTCLVNSERLSDIKFLVGPMEAPIFGHKTILSASSPYFENLFFGPMSTKEPVIKIPDIEPEVFLSFLKYLYTDEFDDTMDDSDAMMLLKPAKIYIVPHLANKCAHLLINKMSPDNVFLIYSHAMMFDEPDLAIVCLRYLDRQIDKVIQTEEFLEIDRETLCTLLERENLRINECLLFKAIMSWTEAECRRRELDVSPENQREVLGNALYLIRFPAMAREEFSIEVVPKGILNKDEIISVFLNLCISNEKKHHRPETPFFTERRVYRPKLQYLTRFSDVLSKVIHYTPHVLSGENIYSSSCKFRTDQRVFLHGVGVYAVSSTINGLKFVATVSLFRSADTSSVPPPNQVLGLMLGTKTVEGSTRSYDFRMPFQIIFEQPLEVRREEDYVILATLKVARDTTTVPYSSLGLFGGTGYGNQIDAYYGTKPLAIVNAACNDGIKVNFFFPSLPSESFTAGQIPQLIFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIB7</accession>
    <name>A0A1D2NIB7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIB7"/>
    <dbReference type="OrthoDB" id="1112980at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="288" mass="30765" checksum="A1A95BD70E9577B9" modified="2016-11-30" version="1">MLEVSDSLVAQCGGSEVADPKVKRETETVEADENDNNTSKRVKSSPPDTGTMNGERGNTSPPDGRPAEKLEVPSTELKLIRKQVLIEKLMSSSGVKEEESMEMDLESGLNGSVDSSNIAIPSLPRQSKGGSKPKPQPRKTFKLRSSVLDRVKTFLPEFRTANDELLRLPDPSKLSLESDHDEMDGRAAEPGPSGVGNRTFVEMNLALVEQSDSDSSTDDEGSVAKKEIKGLPTITKKTSSSPIKSSEDEPAPGSATKGGGNSSADGAETVAQIEDVIKEKKALITELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIN6</accession>
    <name>A0A1D2NIN6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucuronic acid decarboxylase 1</fullName>
            <ecNumber evidence="5">4.1.1.35</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-glucuronate decarboxylase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_01727</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2</text>
            <dbReference type="Rhea" id="RHEA:23916"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="EC" id="4.1.1.35"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:23917"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIN6"/>
    <dbReference type="STRING" id="48709.A0A1D2NIN6"/>
    <dbReference type="OMA" id="KYPKVKY"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05230">
        <property type="entry name" value="UGD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000065">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905625" description="UDP-glucuronic acid decarboxylase 1" evidence="18">
        <location>
            <begin position="20"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="19">
        <location>
            <begin position="79"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN04975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="407" mass="46320" checksum="D3B29FDC667D2FD6" modified="2016-11-30" version="1">MILIHALSLLSVTVCMCHGNYLDDLDESSSMCSKPTSDDPSCDSRLFQLEDRIRDLESRVPKNYPEVKFLTYKDRKRILITGGAGFVGSHLVDRLMLDGHEVSVADNFFTGRKRNVEQWIGHENFELINHDIVNPLYIEVDEVYHLASPASPPHYMYNPVKTIKTNTMGTINMLGLGKRVGAKVLIASTSEVYGDPEVHPQPESYWGHVNPIGPRACYDEGKRVAEALGYAYAKQENVDVRVARIFNTYGPRMHMNDGRVVSNFILQSLQNETITIYGSGKQTRSFQYVSDLVDGLIALMNSNFTEPVNLGNPEEHTIEEFAYLIRDLVGNTNSEVEHQDPMEDDPQKRRPDISRAQKVLKWKPAVPLKDGLQKTIEYFRKELLRSSHSERNIFHPHDLLPESFNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK61</accession>
    <name>A0A1D2NK61_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">E3 ubiquitin-protein ligase HUWE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000019">
        <property type="protein sequence ID" value="ODN05631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK61"/>
    <dbReference type="STRING" id="48709.A0A1D2NK61"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="81" mass="9030" checksum="2E5AE511B5768063" modified="2016-11-30" version="1">MPASQNPILRVTQRLTFSICAVGFSAPLLFDEKKYPYHLMLRQFMEADGLSALFEVFYWAISESSPDAGGPCCLTPMTHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMY4</accession>
    <name>A0A1D2NMY4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hsp90 co-chaperone Cdc37</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_00071</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMY4"/>
    <dbReference type="STRING" id="48709.A0A1D2NMY4"/>
    <dbReference type="OMA" id="AEQCIII"/>
    <dbReference type="OrthoDB" id="440202at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.610:FF:000001">
        <property type="entry name" value="Hsp90 co-chaperone Cdc37-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="10">
        <location>
            <begin position="93"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="9">
        <location>
            <begin position="256"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="305"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN06611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="39731" checksum="9E822E8D44E6BE3B" modified="2016-11-30" version="1">MVDYSRWKDIEVSDDEDDTHPNIDTPSLFRWRHEARVQRMEEMKQEKEEIDKIKADLKARKTVIDEKRKENAFAKKEKLAPWNVDTIGHDGFSKTVINTKEKPSAAPLTEEEKGKRLQTFTKENESLLKKFGMFRKYEDSKRFLQEYPHLVCEDTANYLVIWCINLAMEEKFELMDHVSHQCITMQFLLELAKQLERDPRTCVGSYFTKIAHVEQSEYKQAFESELDLFRKRIRRRAEEKIQEAMEEAEEEERKARLGPGGLDPVESLKTCFETRDIPMLQKALLELPADEAKLHMKRCIDSGMWCPAKEGEQGDGDKPRSTQDSEDDKRFQELQDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0W3</accession>
    <name>A0A1D2M0W3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock 70 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_20082</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008076">
        <property type="protein sequence ID" value="ODM86600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0W3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM86600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="62" mass="6920" checksum="827A03701F05EE18" modified="2016-11-30" version="1">MRKAGKENVDVEMMINSQGILNVTAVSLSTGIREVSVIENKMRMGKEAIDNYLQLERLSHGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M121</accession>
    <name>A0A1D2M121_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">97 kDa heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_20023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007781">
        <property type="protein sequence ID" value="ODM86659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M121"/>
    <dbReference type="STRING" id="48709.A0A1D2M121"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM86659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="355" mass="39391" checksum="0F1BAFB6A5325D50" modified="2016-11-30" version="1" fragment="single">MLTGDGGEGNAITRNDFEEACATFFEDMEQALLTCLEDSEIHVADLHSVELLGGTSQIPAISSLIERVLGRAPSKTLNPSEAVARGCAMQCAILSPSTSNLVRSNYQIIDVQPYPIELKWIFPSGQIGGTEIFALHSPVPDVSSSSLMCPAAKKTAFKVAYGDNEFHPRKTIGKFIIDLNHENDHPCVFTVHFSLNIHGMLSVDKATVDQVVGLHMGETFSIMDLNSDEEMPAGAADLLEVGASTEVPREEHSSIRDVPVDSRPVHGLSRSELEAMILEESRFVALDKLEEERQARRTNLVATMLCMKGVLDGYLKRFVNEEQDRLDEYFTNLEHWLLTKGRMSMERLLIRNSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M124</accession>
    <name>A0A1D2M124_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007949">
        <property type="protein sequence ID" value="ODM86621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M124"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903354" evidence="1">
        <location>
            <begin position="25"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="12138" checksum="AFDC4C293986F695" modified="2016-11-30" version="1">MDLVACTLLSIMLATLCTLKLTQGQLGVVYSPFVKPEDSPTSESYTLEDVKVMMDLVKYDNFKFVATYGVGAPNEPYKLNQTRYHSSSVVHTALAAAEINKKATKSTEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1P8</accession>
    <name>A0A1D2M1P8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vitamin K-dependent protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19793</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006859">
        <property type="protein sequence ID" value="ODM86888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1P8"/>
    <dbReference type="STRING" id="48709.A0A1D2M1P8"/>
    <dbReference type="OMA" id="YYSHRIG"/>
    <dbReference type="OrthoDB" id="5597713at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF69">
        <property type="entry name" value="TRYPSIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="58"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM86888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="278" mass="29910" checksum="2107568DEA1CA02D" modified="2016-11-30" version="1" fragment="single">CPVIITVNKPTEYVCCTSLKYAKVKSISLDEYELKNPKPTEEPPQIPLAPGSQLESKIVSGSPATPGEFPFAVAILESGDNFAVLSAAHCFDQFTSAKVRQLVIKIGDHDITRTGEIQHQDAHVSKLFLHPGFFRTKGYFRDDVALVKLRNPVSSASNIMAVSLHNGSPNINQGLVETVVAGWGKTCSGNCRQSTVLLKTKIQVISNSECGQKYSGTQAPPITQNMVCASGRSSADACNGDSVHNRRWPLIIYSGGLAQQIGIVSWGIGCGQYPGVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M217</accession>
    <name>A0A1D2M217_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_19672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006469">
        <property type="protein sequence ID" value="ODM87010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M217"/>
    <dbReference type="STRING" id="48709.A0A1D2M217"/>
    <dbReference type="OMA" id="NECAWER"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM87010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="329" mass="37832" checksum="58D9BD260A9050E4" modified="2016-11-30" version="1" fragment="single">RSRLRGSVLANRLSSNPDYSVLLLENGGNPNPIQNVPFYFQSLLHIPEIDYGYYTVPQKHACLAMKEQRSYWPRGMGLGGTSNLNCMFWQRSSPHDYDRWAKLSGSDDGEKWHSQKGNGIYVSTVGHDNLVDEFLEAGREMGYPTKDVNGNQEPSFSRLDVSIKEGRRFGAYPGFLEPVLDRTNLFIYRYAHVNKIHLEKKTNRAYGITYKRHGVERFVRARREIIISAGAIDSPKLLMLSGIGPKKHLENRMPNQSPSWEKPDGSHHDNIRSFYCGHSWKNECAWERHNLNTVVDYFSNRRGIMASAIAANAVAYIQFILKRDWKFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2E0</accession>
    <name>A0A1D2M2E0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone H4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006072">
        <property type="protein sequence ID" value="ODM87137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2E0"/>
    <dbReference type="STRING" id="48709.A0A1D2M2E0"/>
    <dbReference type="OrthoDB" id="10597955at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="10288" checksum="8F5ED4543CAC8B12" modified="2016-11-30" version="1">MTGRGKGERSWKGGAKRHRKVLRDNIQVSPKPPSVGRAVTYTSTPRGDRHCHGRCLCSKRQGRTLYGFGVKISKTTTHQSKPNGSFKSHHNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2F7</accession>
    <name>A0A1D2M2F7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_19527</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006025">
        <property type="protein sequence ID" value="ODM87155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2F7"/>
    <dbReference type="STRING" id="48709.A0A1D2M2F7"/>
    <dbReference type="OMA" id="NIWATAR"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM87155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="28820" checksum="91D841CC49BA3264" modified="2016-11-30" version="1">MELIRKSVAKHTQRFDPNNPQDFIDHYLVKIRNTTNPTSTFHGENGAKNLEAVVADLFAAGSETSSNTLSFAMLYLILNQEAQQRAQKELDFVIGSSRQVSLSDKPSLPYTEATLLEILRLSSIAPLGLPHRMLADTMFHGYFLPKDVAVFSNLYAIHHDPTIWGEDVNEFRPERFLSEDETRVIHHEALMPFSVGRRACIGEVFARESLFLFLASILHRFNIESDPECLVLAVETVAGFAVEPKPFKFVLTLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2Q4</accession>
    <name>A0A1D2M2Q4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine/tyrosine-interacting protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19458</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005854">
        <property type="protein sequence ID" value="ODM87224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2Q4"/>
    <dbReference type="STRING" id="48709.A0A1D2M2Q4"/>
    <dbReference type="OrthoDB" id="426001at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="70"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="133"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="273" mass="30662" checksum="04AABF88BE94A1E9" modified="2016-11-30" version="1">MNHGEVEVMEESPVMEEGMTGAFQSMDLGVDDSDKKKEVLMDRYPVPNYPPLPSSKGQVAEEWLYHMRRNMQEIIPGLFLGPYACASRAKLDEMKEAGLTHVVVVRQFMERNLIRANHPDHFKYLIVEIMATLKVSSRISKLSTRLSTSVYPNGGKALVHGSTGNSRSAALVLAYIMSKFGVSLNEASSLVKSKRYSIRVNNGFMDQLREYEPIYRALHSVPDKDCDTRTMKRKLYLDDDDAHPSPSSSYQFGAVPLEETSSFPEGGESPFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M303</accession>
    <name>A0A1D2M303_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005562">
        <property type="protein sequence ID" value="ODM87324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M303"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="32707" checksum="A1526F8E8C97224F" modified="2016-11-30" version="1">MSDSPKKIVDVSGEDYDQEWPSIESKTVAFKKEVEEKSYDGDIDEPYSQRVLDQIRFRNRIQSSAEYLDPVLLKKLFDDMAPPPPTTESPLYTSPSSSKFRALPPGHKSPVKKSLDLLNNSPPPIPLARFLGNKSPPPPQEITRFVGNKLYTPPPPPPPAKEIIGNKLFSPPPQPPPTRFVGNISPPTKFVGNNAPQVKDIIRFVGNNSPPPPPAKEIIGNKLFSPPPQPPPTRFVGNKSPPSPSQENTQTLVWPWVLVPIVLISFIIWMVWFFRRRKHVPLIEDEYDHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M358</accession>
    <name>A0A1D2M358_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005394">
        <property type="protein sequence ID" value="ODM87407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M358"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="24571" checksum="CA8A45F032ADD941" modified="2016-11-30" version="1">MALLDNETVVDLQSDEGTDPNQPLIPSSRCSSNIKKLISAASLFSCAFLSLLEKGSCHKLSDKFGKLRFKATKKSQCKTVASLLEKEKETKIVLEATRPDEATQSTNDAVPVLQSPNSGGDGIESIQMRTNGNAPTINNETIVMQLFQYRENQLTSIYYDCSKENRLLKRVENTLCTSFRLLERAHQQNWIVNADIVGVEYNIPICSFLKAEKLYCKNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5X4</accession>
    <name>A0A1D2M5X4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003777">
        <property type="protein sequence ID" value="ODM88314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5X4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="195" mass="22026" checksum="5340587714E81F8A" modified="2016-11-30" version="1">MSRQIGIVKKVRIKRFSAPDKQLSQVPDWTSQTDHAHSRMKSRRQSQSRIQNSESRQSLVSLAAPPQWIINFCKSLPLEEHSNPVAGGIGFKHRSLIFTITTNGSLSVGTYFSSFLATTSEWMPYGLQIQRRSRPNSNSSISLNQWLRKKTGLNPQRARLLNLIFIQAASWKQVQKDTKAVVCEVGWCEATPACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5X6</accession>
    <name>A0A1D2M5X6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras-related protein Rab-39A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003675">
        <property type="protein sequence ID" value="ODM88378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5X6"/>
    <dbReference type="STRING" id="48709.A0A1D2M5X6"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="246" mass="28324" checksum="52D7F4BE9F1406C0" modified="2016-11-30" version="1">MVEPIFDYQFRMILIGDSTVGKSSLLRFFTRWQISDPTVGVDFYARLIQVRNGTRIKLQLWDTAGQERFRSITKSYYRNSVGAIVAYDITSRESFERIPNWISEAKRLIEPFSPTFLIVACKSDLESQRVVPVEEDSHTPTQWGSTLLKRRQGAGTMWKRRFSKLLRKFTTESSRESTKSMMRGSMGLNKLIPEMETILCCLKALQKNQSAADGHGFIKAVVDSVLVFMFLRLSCILKLLTQFYCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6K5</accession>
    <name>A0A1D2M6K5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003402">
        <property type="protein sequence ID" value="ODM88596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6K5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="114" mass="12795" checksum="2A6EF46A98D7326F" modified="2016-11-30" version="1">MSAKGVEALLKFIYYSNVDDPMSSCSVALELLKGGHQSYAGNLSGQKYAWFDIDTALMLYFWTLKVDGNEDLKWKALRVIKSKGDDLEGSTVFEKLLKEDTKTATKLIAQCFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6Z4</accession>
    <name>A0A1D2M6Z4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_17935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003251">
        <property type="protein sequence ID" value="ODM88747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6Z4"/>
    <dbReference type="STRING" id="48709.A0A1D2M6Z4"/>
    <dbReference type="OrthoDB" id="6590017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007588">
        <property type="entry name" value="Znf_FLYWCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47160:SF10">
        <property type="entry name" value="MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47160">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04500">
        <property type="entry name" value="FLYWCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FLYWCH-type" evidence="5">
        <location>
            <begin position="254"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="MULE transposase" evidence="6">
        <location>
            <begin position="385"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="71495" checksum="D8F6A43FD83A29A6" modified="2016-11-30" version="1">MERTKREDGEKRQELERIVQNIAGQMNRSYHFARVVGTGETAVIFSLHPNPPFPFRHLDDVPPPPPETMLQEWATEKDKEIQSCENEYEMKEDVLGLGGSGSKLSDDSNGEGENEGADQSGLIDVEDIEDQMDAETDDTADEAVKEIRYSKHSKRQKLDLAEINLYTEPDDCCKEASRSAMSEGLLPNVMNLRSHITQDEEYYVTGRIPPRASPPKVLLPPRIFPPMAFPPKTIPPKPLPRTFSPPLPFLPKQGAAKNSWCCTEKRNSKCRGRAYTANNEVLRVCDEHNHAPDAAVIEAKDVRSKIKMAAVTLPIKRTIRKDRVKSQNSHPVPTSLLALHIPAQYQQTTKRENFLLFDSGPCSDRMLIFGTMGNLHHMQHSPDWYADGTFKVAPELFDQLYTIHVARFNKVIPTMYALLPNRLESTYVKMLNALKELVPNLKPVSVTTDYEKAAKNAFKSVFPNATQSGCLFHFGQCFWRKIQQLKDVSSKYVTDPDFALQVKCLTALAFVPPPSVKDAFEILIADEFYSSSRDMECLVDYVEDNWIGGNRRGKARPPRFDIAEWNYFHRVAEDLARTNNAVEGWHRGFQSQLGAAHPTIWKFIETIRKQQSLNELQMEQHLAGGTPQPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M704</accession>
    <name>A0A1D2M704_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003236">
        <property type="protein sequence ID" value="ODM88753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M704"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26777" checksum="FDA8B9A68B547C8D" modified="2016-11-30" version="1" fragment="single">NHTTFNSICRHFMFSHGIPSFISNAFSISTKMPIRCCNPCPCMPLKLAVILVAIVDAGLKLIASFVVRSSLADLDEFLKYADFEEPPRPGPTTEEKWAPIRNQHVAFLVVSAFGVFFAMVLLFGALLTQTKLCYAWVVGSILTLILYLTLFGIEYKEKTKEQYFFNTDTVYMLIWKLGVKTVPFIYYTFVVLAFINQVGEEMREPRQSGGEETVQGGSPPQDQPVDQPTNVKTEIVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7F5</accession>
    <name>A0A1D2M7F5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003110">
        <property type="protein sequence ID" value="ODM88854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7F5"/>
    <dbReference type="STRING" id="48709.A0A1D2M7F5"/>
    <dbReference type="OMA" id="MKEEMYL"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903559" evidence="1">
        <location>
            <begin position="29"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="125"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="278" mass="32495" checksum="5C1A8EE5D505450A" modified="2016-11-30" version="1">MWVKLWFPEGSKWVILLVFLSILNAVSATVAEKDMQLTANEKEALSQFKEKVDRFLNLDFMKTDFYLVRWLRAKNLNVPQAETMLLQHLRWRHVNNIDTILKEDWSDMETDYPYTMDTINLELMPIGTVDIYEWDIRRAVLQGKTHRLLRYLYRLLEEITGNIFEAQAKGQNVTRFVILGNADGFNVVQHACPLCLPSWVQFVRTFEAQYPGFLDEIIVVEATSTVNVVIDLIRPIISPATRNALKVFGQNREKWMTYLDTKISRDQRRPQYGGTKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M868</accession>
    <name>A0A1D2M868_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine-protein kinase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002908">
        <property type="protein sequence ID" value="ODM89104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M868"/>
    <dbReference type="STRING" id="48709.A0A1D2M868"/>
    <dbReference type="OrthoDB" id="6763324at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="12440" checksum="5D49F9306F75749A" modified="2016-11-30" version="1" fragment="single">QRFSIDLDKSRELEIDIYWRDWRSLCAVKFLRLEEFIDDVRHGMALQLEPQGLLFAEIKFLNPMISRRPRLQRQRKIFKQQGKNVPRPTQLKYQCRNMGKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8U2</accession>
    <name>A0A1D2M8U2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative E3 ubiquitin-protein ligase SINA-like 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002682">
        <property type="protein sequence ID" value="ODM89390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8U2"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="203" mass="23187" checksum="FCC35F1B84CFEC42" modified="2016-11-30" version="1" fragment="single">MERLPHSDNSWEPQENVNLALILEFERKMKKKGTEAEMRQEPPNTGANEGLLLLRKGKSMDKKNPMLLELTSHRSRKTFSALRIDKGSGARDFSVFRRPYYLPPLHFQGQPRSLSSVQYEFGGKKIRSRVLEEILDTHDFECKFKDNGCAQLCKRGELTSHANLCTFNPDTVPLCQQFGILEGCGFRLGSVSRAEEIIAHFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M909</accession>
    <name>A0A1D2M909_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002618">
        <property type="protein sequence ID" value="ODM89476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M909"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="162" mass="18550" checksum="281C574FA29B7AFB" modified="2016-11-30" version="1">MKAEQEPLVLHVGGKELPTTLTELLSTPQSLCGIGALLFIVVGGAIRLTRMSATSSIQSYHQYSDPNADEQGDRITKTITPKGIWAAWKKFWGKLPRRVWNFYIDAFLVPAYRQEWDKYKQWSYRSQTRQPKTPAVRRRIRIQKRLCVKPTSSTPPPLSHPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9C3</accession>
    <name>A0A1D2M9C3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002523">
        <property type="protein sequence ID" value="ODM89583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9C3"/>
    <dbReference type="STRING" id="48709.A0A1D2M9C3"/>
    <dbReference type="OMA" id="TSALICN"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF130">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="86"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="267" mass="30840" checksum="9908FB1964AE24A4" modified="2016-11-30" version="1">MVKLNQEPLVETGLKEMRQIYKEFQGKEIGNKSVNDFLATSFNDEALLKRYLIGRKYRPQHAFDTLLSYAEVRFVKYPEMFPAVLPPKELLLRDNQPVFGILKGRDSQGRIVGYFRSGAWDPSKCTLEELAIIVIPIMEKALLNKDCLNNGIVFVHESGGMGFSHAKHYTFSAIIRFLNIYWHSFPLKVKGLYLVNVPTIFTYIYTMIKPFFPKKLQDRVIFFSTTSRKFKELHQRLSPDILPTFLGGTLDPREANDPEFIDLFSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAC6</accession>
    <name>A0A1D2MAC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002287">
        <property type="protein sequence ID" value="ODM89930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAC6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="470"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="58155" checksum="EEAB23C5FA8FFE4E" modified="2016-11-30" version="1">MFIAANGATFKHPNFAVWFDPYVSTATRLHSYNVSGLIPIVSKIASRFSRIMMPYFSIYNDLNTYTPAFIPAAVATFNKLHRKPQQKPLELIMPFSQTEPGDGSVHTDFDMVQELGNKANSIFPGTVKRFIFRYQTLSSNVFSNVKQYLAYINRAVDRSKYSLGADILLSDCGGSSKALPAYLSPFLMYFSEVLFTYWPENQKSLSGPVATAQHFSKMFEQCVQKMEREWGSVAVGFKTAWHGTASENYSENSLHLVQYWELMNEIAINLNKTAVMVEAFNTNHEGRSSEFRRQGWWKLVENANYNDSSQYVFEEKMTAIQHLLPGGKTEIDNEFNSTVQHNLNSDNISTTSETSVSTSRQISLFRFTFTTEQETTTLISAAEMTTVTRQSETTSFAKETTPTTIETIISETTSPFQLRSKTYLTMNSSQAVSDKLELDSSQHFNLQLESPQNTHREASDTSEVSTAPNLIISAIVATAMILLILTMWWVVVYAFKSLHRRNSSCAHEQIVFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAF8</accession>
    <name>A0A1D2MAF8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002264">
        <property type="protein sequence ID" value="ODM89978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAF8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="15277" checksum="CCE01789F1CED249" modified="2016-11-30" version="1">MNTSPLPFSPRLRLRQRWTFGSPSSLCPSCHLLQLRSPHFPICPSSAYAQVPQVAYQQAIAAPVAVAQPIIRQQLPLPNKLLSQLPPTPPSRTVSPNLPAQSLLPKFHKSHMLNKLSLPPALSYGSIGYGYNGALAGGLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBS0</accession>
    <name>A0A1D2MBS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sortilin-related receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001981">
        <property type="protein sequence ID" value="ODM90413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBS0"/>
    <dbReference type="STRING" id="48709.A0A1D2MBS0"/>
    <dbReference type="OrthoDB" id="8251576at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="196" mass="21454" checksum="C88DD91AC4B24845" modified="2016-11-30" version="1">MELTVSTNAEGGRQSAPVKDSECSQCIPLTIYWEQPKLPLLVKKKGQESYVVELSKDSNFTNAKQYETIENSFKFDEIRDDGIYYVAVRVRDHEGLLSPRSNAILVQQSGGASPIVVIPGSSALAITITVLIVIVLLVAVLGIIVVRHKRLQISFLNFASSHYSSQSGAATFQQSVDEQDSPVIRGFSDDEPLLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCB8</accession>
    <name>A0A1D2MCB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box/WD repeat-containing protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001876">
        <property type="protein sequence ID" value="ODM90625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCB8"/>
    <dbReference type="STRING" id="48709.A0A1D2MCB8"/>
    <dbReference type="OMA" id="HECDICT"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021977">
        <property type="entry name" value="Beta-TrCP_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12125">
        <property type="entry name" value="Beta-TrCP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01028">
        <property type="entry name" value="Beta-TrCP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="102"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="20666" checksum="30128DCE3BF7369E" modified="2016-11-30" version="1" fragment="single">MLKLLHLIQMSSIDDSVKMDVRMVEAGEEGQELPQRVLDPTYLADKDLCLSRFDEWTKEEQSDFIENLLRRISEDQQAQVGEFVTPLLRRDFVTLFPKKGLDHIAENILSYLDVKSLCVAKLVCKDWNGVISNAMLWKKLIERHVRTDLLWRGLGERRGWYVQFQSWLCIVIKGLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCU5</accession>
    <name>A0A1D2MCU5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-secretase subunit Aph-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the APH-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001789">
        <property type="protein sequence ID" value="ODM90805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCU5"/>
    <dbReference type="STRING" id="48709.A0A1D2MCU5"/>
    <dbReference type="OMA" id="IPAYCIL"/>
    <dbReference type="OrthoDB" id="6507463at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009294">
        <property type="entry name" value="Aph-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12889">
        <property type="entry name" value="GAMMA-SECRETASE SUBUNIT APH-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06105">
        <property type="entry name" value="Aph-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="28390" checksum="488B5CE0E97ABC15" modified="2016-11-30" version="1">MAIMEFFGCSFIAFGPPFAMFRHTVAHDPVRIIILIASSFFWLLSLLLSSMWWALLKPYDVPLAWSVGMSIVLQHILRFLVYRFWKRVEWGLKLVADRDSKTGVVDNKKYIIAYVSGLGFGIMSGAFAFINILAESLGPGTVGIRGAGDSPMFFVTYALTTLCFILLHTSWNVIFHAGMNKRNYGLTFIVIVSHFAASSLTFFNKDKLYWASILPNYFNLLVSGWLAFRCAGGRLYWMKSEHYHRLHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD59</accession>
    <name>A0A1D2MD59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Gastrula zinc finger protein XlCGF26.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_15769</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001746">
        <property type="protein sequence ID" value="ODM90915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD59"/>
    <dbReference type="STRING" id="48709.A0A1D2MD59"/>
    <dbReference type="OMA" id="SEFIMVE"/>
    <dbReference type="OrthoDB" id="6782020at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000110">
        <property type="entry name" value="Zinc finger protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF70">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="181"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="365"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM90915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="474" mass="52491" checksum="1C7A87B425583A46" modified="2016-11-30" version="1">MEGEEELVAELKTELATVVEVLCVLHDFIDNLFGVKFQTFCESNSQLASQVGVLKDLRWKHLGDCIPRRSTSSSGGKSTEREGSRLQLIGSPEIVDVKCEAEGEEEVPDFLEDVDPFGGDGEVSSKNYQDQHHHYLSGYEGMEQEMSPYQVSTITGENASNSLSTTGNTSNRYTSEFIMVENEKDPLQETVVDEEDSVSSDDSDDWNPRMEDPTSAFFGSRKKQLQKNQKTPSAPAPRGRPKRVEKDKGFLQQQFTIQIQPQLKRQSSTDSSKGDGGPFKCDQCPASYSQEESLRSHQKYKHNPSRVQCTCHLCGKSMVDKYRLQRHLRLHTGEKPFSCQYCGQRFYRKDYHTKHLQRKHGLVNSAPSSSSTTSKSALKKALLAKTPPEPSKSAGGAGSSSKSSGSSFITPSRSSTSTSSTHHQQPSSTQSAASSTAVKQEHGFLDYFSNNPNSTSSLVTMTSLTFDDLINEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEC3</accession>
    <name>A0A1D2MEC3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001586">
        <property type="protein sequence ID" value="ODM91349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEC3"/>
    <dbReference type="STRING" id="48709.A0A1D2MEC3"/>
    <dbReference type="OrthoDB" id="3565419at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="524"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="620"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="653"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="682"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="184"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="707" mass="80554" checksum="D754EFD01396CA5A" modified="2016-11-30" version="1">MTTTKCFSSHCIFCTSQCSPSFTIINGKPVKLKSENGTQSQSFLSSNFELGAPDDSSIETHLKVIFILRKILNIGETTCSNFLGKCEGQFHPGLWISVCSSCDQLVGEFWEKLKEIGRLERRLKEIKSQLTGFVQDTQAFKGDATREDHVWNEIREVVVAGLGEAKASEKAEHFTFDEVDSIDDVSIPSPLQDNDPDFNLEMPNEEEMEDSNLYAPPSTEDNKTSTKPKRGRPPKPENVTNSSPKKMGKKLCYFKCPDCGDLSGNMVRFRQHQQLHKNGTGVTCAECGWLTQKLSSHMASWHSQTQTGNIIEKLANRIIKEVKTSNGERVPVPENAFESIRRPNGKRKLRCTLCPAAYTHLFRIRNHLEVHSSGNGIACEVCGWVMKPEKMSWHVGKVHGSKSKEVKKNPYKYPKKNYRFDCNDCPAYYTRLADLQNHKKLHNTGKGIVCMECGWLVQKLAQHKGKHHPKNSEGLKIKRKVESLENVRVSEEIPYYCSHCQMIYPTINKLITHVNSYHAAEGLLSCDSCESQFESTQLLKLHKKREHGEETEANEEDDCVQKCQFCDEVFESKMKKDFHVAKTHSDRLLFCVPCNLSFKGFGDFQRHMQTSRAHANQKRFACELCGKAYTENYALNCHMQATHYEFLGFEPPHKCSECGKVMANKGSLDDHMRSMHTKQFKFTCEYCAKGFNNRGRLVEHVTKKHQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEL7</accession>
    <name>A0A1D2MEL7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation channel sperm-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15228</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001543">
        <property type="protein sequence ID" value="ODM91458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEL7"/>
    <dbReference type="STRING" id="48709.A0A1D2MEL7"/>
    <dbReference type="OrthoDB" id="6282829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036128">
        <property type="term" value="C:CatSper complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030317">
        <property type="term" value="P:flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060296">
        <property type="term" value="P:regulation of cilium beat frequency involved in ciliary motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028746">
        <property type="entry name" value="CatSper1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47193">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47193:SF1">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="8">
        <location>
            <begin position="210"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="563"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="608"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="633" mass="73258" checksum="C6C5ED8CC931AF0C" modified="2016-11-30" version="1">MDTANDSKRTSGGSTGKKKVSTSPQDELHTLWRELVQKARVHEMVKCLQAEKKKLKILQQTVEPDNLDFLEFAAHQQAAKSIAESEGTEEPWDDEVQKSDDVDVVEKVTRSSEVTTRASLTKRDTYAKMGEEHHANIPKSAYNAQRNAAEILSNKPTLTDQEFEDIVELCEDKVEQKALREAFEEKKAREKYLHNADERRTMLYNFINSKFFTNFMLVTIITSIVGIFLLTFEFIAIRFAWPLIMLDSCIIGIFLVEAIFKVTIYKEDYFKQLWNILDMLIIVVHFVELAVDLITRTLALSTDINANIGFKFLKSLRALRLLRVIKFLPNLQVIVATVFQSMLSIGSIALLMLLFIFVFAVMGRGLFFERLPDKFGSLWLSFVTLFQLLTLDDWFELLEENEDDRGIDDDSLRNEGDDRFAYWLMFVYLFGYLVIEFFVFLNLFVAVLVDNFQLTLADAEIQKQKEALEELEAQKKFEDLKKEGSEMDTIDEEVKKDFNEGDQLGLTVEDYFPVDPDSREAELLGEFYKDLNSLDFNRFLWKRRLTLFNMIIDTALSSRANATQVVPEKVTEDDVDHHHDTHKTEDESTQTNRGRLSEKQTAAYLNEDHPSNLPAWNSMPQQSQTRSFFMSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF36</accession>
    <name>A0A1D2MF36_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ZP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15073</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001480">
        <property type="protein sequence ID" value="ODM91610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF36"/>
    <dbReference type="OMA" id="MRGYDAR"/>
    <dbReference type="OrthoDB" id="6351704at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560">
        <property type="entry name" value="CYPHER, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560:SF5">
        <property type="entry name" value="CYPHER, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00241">
        <property type="entry name" value="ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903920" description="ZP domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="613"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="ZP" evidence="4">
        <location>
            <begin position="195"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM91610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="665" mass="72281" checksum="39917C416E302335" modified="2016-11-30" version="1">MQRFAITCTHGFILVLTLSSTLQLTNGSHLPSSYLVQKANSNNEYESNSNANNNNAGTIVPISTTVSSSDNVATDSTTTTIVTPEAEPRPGNLEIVNVVINDVLSTTTQESASTSTQPTPTSTIPSALTSSYEDNADSNLNYISEHDHYDEYAAMKAALEKEKSGEEMKMPPQSNRHPYLLQAADGRNYASIEAICDDRRMTILGHFDEIFKGRMYSLGYSDEVECGTSNAKEPSHNITFSLPLGSCGVAMLALDDNLENDLRHEVTLYIQYSAFLQQVVDEKISVSCTEIKKTPLEEYITSNEEVERGSNRQGRRMGSLAEPGKFGATKISSRIGESWMEILAGKDPSPKSRKLSPVSVGEDVTLVISTKVMRGYDARIVNCSAHDGSRTGTSDGSRAQQILDSAGCSLDRSLVPNLRRRRLPIESRNRLITLHFATFQAFKFPERDHLHIKCAVAYCQGPCPQEPCDSVLNHFGSWRDKYGRIADVLVDSTEVVNSVEVVAPELDDLGRSQQYDRHPAMTSGSYSSLSGGNSLTPASPSDISGRQFGGSEPTSSYNSYSSNGGSASAAPSAAASAGQSMFGNSQVPLLQPNPNGEFHSSIGNSVCVSPGTVILALVILGVVLVISATATLWFALKRSEAKKYRHVKHSPFQHGPQPYYRFSHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFB8</accession>
    <name>A0A1D2MFB8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001454">
        <property type="protein sequence ID" value="ODM91668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFB8"/>
    <dbReference type="OMA" id="NNCITHV"/>
    <dbReference type="OrthoDB" id="8250323at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like fold" evidence="2">
        <location>
            <begin position="66"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="246" mass="28597" checksum="98A80D586DE8884F" modified="2016-11-30" version="1">MGCCSIELSLTNLILIGVLFFIGKKAIKFFQKWKVEKMLEKWDEAPKDKLILHTLWRCKPMPSISPFGLKLETYLRMAKIPYEGKLPWITYQGVHLADSHLCIEYLNKKFDISLKRALLRNNLLLHAHVESSDTPNWNRERELKQRMVNQSIGKHTPTEIYQMTEADLHTASAVLGTKNSLVEMSHVRKTVLFWLCRTSYMGSPGSSFERLCEGELKNLKEYCERMKDRIGQIGNNAGINLEWFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFL6</accession>
    <name>A0A1D2MFL6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-glucuronosyltransferase 1-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15007</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001452">
        <property type="protein sequence ID" value="ODM91681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFL6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFL6"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25683" checksum="91FA548B04A5980E" modified="2016-11-30" version="1">MGFFGRIQASVSYLCHFNKQFRGLPGLDLVLREKLGMPDMPPVIPIGGMHVSNSENPCRKRWKNSLKEAETTASFIAVGKIKTGFLWRWDGEKPVGMPDNVIRKYEDLLRMVTVKQNKITNAERLHRTGRGIRLDFGSLTEPQLEDAINRLLTDPRIKHEMKLTSARFKDRPSKPVDTALWWTSYIFRHEDTSFLRPGRLASSLSWYQRRQLTCGLSYQLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG60</accession>
    <name>A0A1D2MG60_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM120 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001391">
        <property type="protein sequence ID" value="ODM91872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG60"/>
    <dbReference type="OMA" id="DRYRYKQ"/>
    <dbReference type="OrthoDB" id="2015098at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012926">
        <property type="entry name" value="TMEM120A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21433:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 120 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21433">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07851">
        <property type="entry name" value="TMEM120A-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="346" mass="40701" checksum="A2533333537A5264" modified="2016-11-30" version="1">MDLDTGTNIKSAVKEFDNLSEKFKNLKNLHKYYVQTLDEAAVLQAKCVKELNHHRSHLGKIKTSIKKYGRKPELKEVVEKLEQKLIRRKSALLEMDQSLPKKIGLYLWLILGNVNVSIFNEEEKCNYKDEYEKFKLITNGIGLLMSIANIFKNLTALDLLFKVLLVWYYCTVTIRESILKVNGSKIQGWWRMHHFLSMVLSGVLLIWPNNSVYYSFRMQFMWFNVYTSLVQFLQCWYQRGCLYRLKALGERHNMDITIEGFHSWMWRGLSFLIPFLFISYFFQLYNSYVLYQLSYDSKATWQVPVLSALFLVVSLGNIIIIVAVLRNKLNSSTFTKLLGRDRPCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGE0</accession>
    <name>A0A1D2MGE0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dipeptidase</fullName>
            <ecNumber evidence="1">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01001345">
        <property type="protein sequence ID" value="ODM92049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGE0"/>
    <dbReference type="STRING" id="48709.A0A1D2MGE0"/>
    <dbReference type="OMA" id="HIWHVAQ"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="328" mass="37630" checksum="F7E5362C98A5BD82" modified="2016-11-30" version="1">MNVHNDLPWNIRKFVHNQIQDFNFSSDLRKVEPWSRSTWSHTDLLRLQEGMVGCQLWSAYVPCGAQHLDAVQLTLEQIDVIRRLSEKYSHALEFVTSSQEIVSAHRRGKIASMVGIEGGHSLGNSIAVLRMFYSLGAPFLHLLNIVVFPFQKVIKEMNRLGMVVDLSHVSVQTMKDALNTSRAPVIFSHSSAHSICNSTRNVPDDILRLLSINGGLVMVNFYNYFITCNESASIGDVIDHINHIRSVAALLGLEDVSKYPNLFSKLIEDPRWSTEDLKKLAGKNFLRVFRRVEEVSWNFIFLLYPPFFHFFSRKRMHVKIYKLNGRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH43</accession>
    <name>A0A1D2MH43_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine palmitoyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14432</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001284">
        <property type="protein sequence ID" value="ODM92253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH43"/>
    <dbReference type="STRING" id="48709.A0A1D2MH43"/>
    <dbReference type="OMA" id="DEAHATX"/>
    <dbReference type="OrthoDB" id="65434at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="82"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="306" mass="33996" checksum="4FB8C353EF810C79" modified="2016-11-30" version="1">MEFFFWWDSSMTFSVRGQPRRKIGYVPLYASFASFYTRHVYRKIRDCWNNPVTSVPGGYITLLERVTKDHGWTFEITDKKVNCINMGSYNYLGFAENHGPCAEAAIEAVKSSGVGTCSSRTEMGNSKVIKELNQLVAKFVGAEAALTCAMGFATNSMNIPAILNRNCLVLSDEKNHASIILGLKLSGAKLKVFKHNDMKSLEKGLRDGVIKGRQRTGLHWDKIFIMVEGVYSMEGTIVNLPEILALKKKYKAYLYLDEAHSVGALGPHGRGVVDYYGCNPKDIDIMMGTFTKSFGSGVATSPDRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHF9</accession>
    <name>A0A1D2MHF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001234">
        <property type="protein sequence ID" value="ODM92429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHF9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="647" mass="73310" checksum="13A633ADCC215BC4" modified="2016-11-30" version="1">MEECKLVSYKDIEDKGLHHRWENSKQRPIASVSAFSMERNQEEFINKCSSPVICGPTFKVDPAPQKSFHMDNSSMNNLLIRFDKVELDEEECVVTEDFNANRQGLLDPDSVPLHSDEWYSFQPLANCGCPFSKLHHSGLPTEFLHCPLPRTNNDMRSKQILAGMNDLSTGVSIKVQFIVNNLNDCLGIWPQLFLQKLNAILVHGDRATIITILTKDDFAILKQIVSYYSKETKCSMVFRYFCFLYNAFSRNMIQVLPSIIKNQLLIQLQIDFSLASQDSCRCKLNHSCVCQCEPDEEHRNVGSLEQLKITAILMYYLVCKIGNHAVNTNDIYEATCTHLNIEVSKFIDESVVPLYIKLYEKSKDSETPAESNLMELLSHLLIGYNCMPYQKTNGFVSAVHRMLDMGYLSSAVRMKDIFLNVFQRETDIIYKVPGSRLMFNVPELKLNFTTLGLPGAIKALQSLISEIEYGILTRDELASLMDTVVSIQMHLSQNGLWNVDYENIYLHCHQILGVLQKKLGNPITISEIKLDSDDDDMDSTNEKLNSLPAPILIDSSTSVSSSTSQSRLHPQPEKVKGKGMEVEGSEDDDGWVSDTRRISKIRKGYVNERHGGVPGRAQIIFHWISNGFNRLAENCAKLCQCNGRLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIX8</accession>
    <name>A0A1D2MIX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Glycerol-3-phosphate acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_13823</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001133">
        <property type="protein sequence ID" value="ODM92862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIX8"/>
    <dbReference type="STRING" id="48709.A0A1D2MIX8"/>
    <dbReference type="OMA" id="TFPADNL"/>
    <dbReference type="OrthoDB" id="10051137at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07991">
        <property type="entry name" value="LPLAT_LPCAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045252">
        <property type="entry name" value="LPCAT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF2">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="16">
        <location>
            <begin position="237"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="440"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM92862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="480" mass="54952" checksum="65CE20CD4E3D135A" modified="2016-11-30" version="1">MSPLRLSSIKMQLLISAFLTCLFAIPTITLFTLGLLHKIFGVREKYKEFLLFIFEKGRQKIEKSQQRQYPDLVIEESDGEEDDEEHYQKRPIYKETDEPNPDFDWTDSFDMITSGIQSIVQDQVTHRFEAEELHSWNLLTRTNQGYEFISIRLTLIWILGFYIRYFILLPLRVAILVLATLTLTLSTGLVGLIPPRMNKIKKVLNGWACKFSFRLLSRVFSAIITYHDEEYKPNGNGICVANHTSPIDVVILSCNATFSLIGQSHGGFLGVLQRALARASPHIWFDRSELKDRAVVARRLKEHAHDPTKPPILIFPEGTCINNSAVMQFKKGSFEVDSVIYPVAIKYDPRFGDAFWNSSKHGMLHYIYRMMTSWAIVCDVWYLPPMYRMEGECAVAFAKRVKAEIAYKGGLVDLDWDGGLKRAPVKQEWKQLQQKEYSRKIINNNQSDSEAHDDDNSNNGNSSRRSSNGSSTAAVGEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ77</accession>
    <name>A0A1D2MJ77_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13616</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily. Sigma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01001082">
        <property type="protein sequence ID" value="ODM93067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ77"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ77"/>
    <dbReference type="OMA" id="YNEIRPY"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000030">
        <property type="entry name" value="Glutathione S-transferase S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="90"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="25010" checksum="34D1620C09624DF7" modified="2016-11-30" version="1">MTVPKYRLTYFNWMWIAEPTRFLLSYVGEDFEDVRLSYEEWMKDDPKINKNDFPYGKLPVLEDRENNLKLGQSFAIARYLARKYNLVGNTIVDAAKCDEYADVLKDMLSEVEPMWRADEKQKAEIKAAFLEKTVPRYFSVIETDLKNNGGKYLVGKTTTWVDFLCAHFTEMFQIYLNTDILTNYPALKAHQHQVFEISAIKEWKDKRPVTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ84</accession>
    <name>A0A1D2MJ84_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein Star</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001134">
        <property type="protein sequence ID" value="ODM92844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ84"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ84"/>
    <dbReference type="OMA" id="SWAINAC"/>
    <dbReference type="OrthoDB" id="2154188at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="131"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="312" mass="35669" checksum="2C55FDE50E2FEFD9" modified="2016-11-30" version="1">MVKEVVKHTSFRWKLCIGAVSIAFLIFMFRLYATTRPENLSENAIIESTGASNGLDGGFSSDPLDILYVEDNLNSLNQNDPQLIQYTRIRHLTPPSKLPYNFQRKGNFKDAFSGWVTNFFKDKREGIFIEAGAHEGEEGSHTLFLEKELGWTGLLVECNPTVVPYLRSKHRKAWIADVCLSPSPYPATLNFSNPTNWTYSGTFKKPWNLPVPTKWTSFEVQTMPLYTVLAALAYTAIDYFSFDVEGAELAVFKNFPFELVTFKVLVVEIMFYTQVERQELHDLLISKGYVFVKDLQVDKVYVHNSVKDMIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK19</accession>
    <name>A0A1D2MK19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_13441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001041">
        <property type="protein sequence ID" value="ODM93242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK19"/>
    <dbReference type="STRING" id="48709.A0A1D2MK19"/>
    <dbReference type="OMA" id="CKKHTIH"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01476">
        <property type="entry name" value="Ribosomal_L44e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM93242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="104" mass="12584" checksum="060F948D2E90C6F3" modified="2016-11-30" version="1">MVNIPKQRKTFCKKCKHHKLHKVTQYKKSKERTASQGRRRYDRKQQGYGGQTKPIFRKKAKTTKKIVLRMECTECKYRKQIPLKRCKHFELGGDRKRKGQMIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKB3</accession>
    <name>A0A1D2MKB3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_13259</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000996">
        <property type="protein sequence ID" value="ODM93423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKB3"/>
    <dbReference type="STRING" id="48709.A0A1D2MKB3"/>
    <dbReference type="OMA" id="CENCEIT"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM93423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="467" mass="53116" checksum="864FAF3D9C9970F1" modified="2016-11-30" version="1">MGNYLQVSSVATKRLLKVIGENNEVFCENCEITVITPICSIYSQLLSVQARLSEELEKIQNVVDKSTAESFTTNLPINPLEKDSLCYFKPFRSSLTAKCQLKRQELLPFITPETLIKTSETLESDAEVDDDDNGHVSEPLDSSHLSKCENTGEEDETNVQEYLINIELPDEIKTETEEEVNDSAFYLDSQLTSDPQPSRKALPSPLKVKRHMKSSHDIPPIRCSFCNTSYSSESGLHYHINTVHKPKTLLCSHCPVMFSHQQNLQRHFVSKHSATLSSTPLPTRQDGEPLNCPTCGKLFPTPEKVSIHIKNVHSKKHHQTNQVRNPKTEICQLCGKMLATEKSLQQHVARFHPTEVQTESWAKCPSCDEPFYKKYLLEHHLRSCQGKKRDETQNAAELQRRDYGNLAQTPLHLRCDLCNRTFSNTAMKSQHVAQHSSQNFPCTDCGVTYRWASGLAKHRRNQHKQMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML16</accession>
    <name>A0A1D2ML16_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13099</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily. Sigma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000952">
        <property type="protein sequence ID" value="ODM93582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML16"/>
    <dbReference type="STRING" id="48709.A0A1D2ML16"/>
    <dbReference type="OMA" id="WIKQREY"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000258">
        <property type="entry name" value="Glutathione S-transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="86"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="226" mass="26461" checksum="59AC06F6CDEB8DAA" modified="2016-11-30" version="1">MDMDTYKLTYFDLRGIAEPIRLIFRYANIPFEDCKVNFELWKDVKHNFKWQQLPILEHNGKTLTQSVGISRFLASKFELKPQISGNSEETAWVDAKCDEIVGAIHDLRLQMKPFIHSKMGVENPEDGDMLKNTLLTSTVPRFLENLTEILIQLRQNGSVDESGNFIFGKKPTWPDFWLAHFTHQWSEVLEEPQLLDKYDLLKKQQEEVYNLPGVAEWIKERPDSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLF7</accession>
    <name>A0A1D2MLF7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000899">
        <property type="protein sequence ID" value="ODM93876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLF7"/>
    <dbReference type="OrthoDB" id="9949093at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036128">
        <property type="term" value="C:CatSper complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097228">
        <property type="term" value="C:sperm principal piece"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028246">
        <property type="entry name" value="CATSPERG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14327:SF1">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14327">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="29058" checksum="476FC9FB291A4548" modified="2016-11-30" version="1" fragment="single">GHYAFLTSKRELWYGNVGSLNQIRLRPSDTFGMITARQAQVREMSEAVPFSVFFDSDDNLVEMVAVVDKNGDVERISRRSINEKTIRRAKWYIKQLGKYADNLLSKLALIATDQNAKSKDMPAEMLEPLRYQPSKYTIFCPYSSPAFRHNFSVKHARAQTFVFPVPGQHADLGNTYLKSTLLTYQAIIFGLVWNTYLHEPHRTYSYVNLDPFIQWNRNRKDAAIIGALQYVHNNATTDGILVEPVKYSKLVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMA6</accession>
    <name>A0A1D2MMA6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000865">
        <property type="protein sequence ID" value="ODM94078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMA6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="451" mass="49216" checksum="E1C4875CC385C739" modified="2016-11-30" version="1">MVIVNPKLSLPIDLPYKKRQRPFNPSTPLQQATVRYNEAIRKQYNDIQFAKRCENGHISQIELTTVNTIDVSKQVDSQLFSEMSSLKPCPLGKQRKSKKIEACNAPGAVENVHCVPSSSTTTTTATAEVPPPYDCNDMQMFPQLSAAASTETPEGDKYAASHHSRSLRHSRAPSSVMPVEQFQSLEAQAIREYEPTVDSAHDMIFGNVMGVHYGNFIHGHLWSPPEFNNTTTYHQFNANQQQQHAVSNNFCGASKSVGYNLTSGTAGNDGYNSGSSNDSGMGNIGHCSVSAGPSTIIGNSGKNNKRSTSVPRPRTATRKETLKQAAIRCGIITPAVPKRSHYLEQLSVSVPLQLNPVQTDPPVVPVVEILHPRTLIPTCSSEALLEEMRNKIADSEFKKDGAHGTKSNSRISKNEDHGVEPNAKSSEANGRSPSQVRSVSDFRIIDNSPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMJ6</accession>
    <name>A0A1D2MMJ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ subfamily C member 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000831">
        <property type="protein sequence ID" value="ODM94290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMJ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MMJ6"/>
    <dbReference type="OMA" id="EIVNKAW"/>
    <dbReference type="OrthoDB" id="342454at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000112">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042858">
        <property type="entry name" value="DNAJC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15606:SF4">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15606">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="30362" checksum="D4FDDC51098D145A" modified="2016-11-30" version="1">MSAHSSSGSGVEKDGLFQEFYTEVKQIEKRDSVLTPKQQIERLLRPGSTYFNLNPFEVLQVEPDTPLDAIRTKYKRLSILVHPDKNQDDKDRAQTAFEAVSKAWKTLENDDTRAKCLDVVEEAKAKIDANIVEKKKKLKKDGKKNKIEEDDPEKYKHALYVMTMKLFADMERKRRNQEDRDMEERKRKREEELDAEEKAKLEKEWQKNYEESREDRVSSWKKFQTGAGPSKGPEGPQGPVPKKPKKIKTFRPPKHKAESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMS6</accession>
    <name>A0A1D2MMS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000838">
        <property type="protein sequence ID" value="ODM94232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMS6"/>
    <dbReference type="STRING" id="48709.A0A1D2MMS6"/>
    <dbReference type="OrthoDB" id="6366898at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904265" evidence="1">
        <location>
            <begin position="18"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="160"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="36535" checksum="BE7FEBC49EEEF22A" modified="2016-11-30" version="1">MRLSAILVFGCIAATAAVDKSTDFGMRMVVDAYESVCWYEYLKQFPNTDNSAYQKCGTQSSQIQADALEEADGTEKDYFIKNLSSEMDKLPSDYEECSSLLASATPDYKKASRNDPLKDGGQKNYPFRGFSKCLMKTLEKRHGPQALKAVDDERISGSKSVTGALLERTNQWRALHGVEPLKLLKDLEEAAKEYTSELVMMDCKYKKSNSNHPNRKYKGKKTGEVLDSGNYVAFKFADSGYQIANNWYNEIKDYPFPEGITEENIKVYGKVSRFTQTVWKNTEYVGFAYSEFTDCNNFVTVARYYPTGNTKGGFQENVLPPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN49</accession>
    <name>A0A1D2MN49_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aldehyde dehydrogenase family 3 member B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000801">
        <property type="protein sequence ID" value="ODM94479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN49"/>
    <dbReference type="STRING" id="48709.A0A1D2MN49"/>
    <dbReference type="OMA" id="PLVAYWF"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="77"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="503" mass="56558" checksum="3541CFB9B6E2485D" modified="2016-11-30" version="1">MVRRARSVPSEAAEGAAPDVLRQERRDPGGAPHGHEKVDAGGLHVRDRPHEERHPRDDQEPRVLGQTPPPQPELAHSGDRGYILRVPYGVTLVIGTWNYPFQLTLVPVAGAIAAGNCVVIKPSEISSYSAAKIAELIPQYLDPECYAVVNGGSYETDLLLDHKFDYIFYTGSIGIGRKIHAKANKHLTPVTLELGGKSPVYIDDTVDYAITAKRILWGKCMNMGQTCVAPDYIVCTQKVASKLIPHFPAIMHEWYGDNWKAVPDLARIVNKKHFNRVLNLIKTASGQIIMGGETDESDLWIKPTIIVGVKPEDPIMNEEVFGPVLPIMILEESNDCGLEQAIEFINSRPWNPLCLYCFSVNPHVKVQLQDRTQTGNMAFNDTIVQFVIDELPFGGVGSSGMGSYHGKYTFNTFTHERPVVLRDFSFLGDKVGIIRYPPYNKFKINFLSFMLWHWKKFNIFYFEYVPHFICFMLGLLSLVVLDWIYGEGTIAFKIYNAFANRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNB7</accession>
    <name>A0A1D2MNB7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12336</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000819">
        <property type="protein sequence ID" value="ODM94351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNB7"/>
    <dbReference type="STRING" id="48709.A0A1D2MNB7"/>
    <dbReference type="OMA" id="IAHEINP"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000013">
        <property type="entry name" value="lactase-phlorizin hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904316" description="beta-glucosidase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="496" mass="56790" checksum="6F3CD637E0ABB058" modified="2016-11-30" version="1">MSPKFSMVGLVLVALSLTSAQNDSDFLYDYFPEDFEWGFATASYQIEGAWNVDGKGQNIWDEFTHRNVSPIVDGSSGDVACDSYNKYLEDVELLKNTGVNFYRFSLSWSRLLPDGTNRTVNQRGIDYYNKLINALIANGIEPMVTLYHWDLPLALQGVGGWTNETVVQHFENYARLAYSYFGDRVKQWITLNEPFVVCQLGHGDGVHAPGHTSPVEPYLCAHNILKSHASAYRLYERDFKESQGGQVGVTLDSGWYEPEDPNNPDHVEAAERAVLFKHGWYAFPIFFGDYPPVMRQLIDQKSEAEGLQESRLPEFDNYWSQQLNGSYDFLGLNHYTTELVVPENRTDPGYSGDQNTRTYQSAEWPESASSWLKVVPWGFRKIMNWIKNTYGNPTLYVTENGFSDTDAEGVNDQGRVDYYRDYTNNMLKAIKLDGCNIKKYTAWSLIDNFEWARGYTERFGAHFVDFNDPARMRTPKRSQGYLKQLFADNGFPPPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQC9</accession>
    <name>A0A1D2MQC9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_11366</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000686">
        <property type="protein sequence ID" value="ODM95310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQC9"/>
    <dbReference type="STRING" id="48709.A0A1D2MQC9"/>
    <dbReference type="OMA" id="FGVHAIM"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM95310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="288" mass="34165" checksum="4756363EFBD7D70E" modified="2016-11-30" version="1">MSETVETAKVLYSNSGHNGPPVEPHYDDRYLHIFSFEKYDHTKWHDWMHRHWDVSLYASGIYVALIFLGQYLMRNRQPFEVRRALLLWNVGLATFSATGFFRSIPELWYEWTVPATGGLQRSVCFADNHNIATSLWGLLFAWSKLFEFGDTIFIILKKQPLIFLHWYHHVTVTIYCWFAYSAYDPSSRWFCTMNYLVHSLMYTYYAMKVLQIKIPRHIPMAITICQIMQMVVGVIINVNTYYIKLSGQECKRPYSNIHLAFAMYTTYFILFANFFRKAYFRKKSVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQG9</accession>
    <name>A0A1D2MQG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbonic anhydrase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11347</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000685">
        <property type="protein sequence ID" value="ODM95317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQG9"/>
    <dbReference type="OMA" id="TQIHVMV"/>
    <dbReference type="OrthoDB" id="10645406at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904383" evidence="3">
        <location>
            <begin position="21"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="4">
        <location>
            <begin position="56"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="316"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="412"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="616" mass="70974" checksum="6BBA7554FB4C2DB5" modified="2016-11-30" version="1">MRTIMHFAAWTLLTIVITGASQNHNYCIRRNANPGSGDKSENVTLPSASQQQNTTMEASFLEWDKWTEKYPDCNPETNPFASPIDISTSDVISAKSIQTLFIHSGEPERDTYLLSTFHVTDDYHMEALNVKLQGEQALGHATIVSGLGKSSKRFFDSAVLLIKGKDFKGTASINGGIHTIDYKKYPMEIVLTFMTNSGEDETQIHVMVEVMNETNPVWLPLTNLYDKMCAKIIEDTCFGNVLRQNGKDAYDKAVLHYTKLLTKQKEELDRTTYQERYEEIKICYEIVKCCDSEKLKELHDEANTEDVKIQGCHKDLSKHQEFMETARKKIEELKTKIQQLKENEQLYDNEEDTLNQENLEFKKLKEREDELNECITKHGNRYSELQKQISNSNRIRKENEIGSDDQHKFKSVAQVLEKMNEVKKNMEELEKAKISYENARYELEAIESIPSRSVDVELPFQISWLFPPYGGHYFYNGSSPLPPCEKKPFAIVLEKPISISSEQLLVFQKIPSIHQRDPSVWKRLCDNSLSDGQKAKILDTMDKIVSQVPKNKVAVARKVWYNPKNLQYKMDDGVHMKSSTRRKLKLELENEERNKASAKFCQTVLNLICVIIYTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRB6</accession>
    <name>A0A1D2MRB6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Lissencephaly-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11095</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000649">
        <property type="protein sequence ID" value="ODM95583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRB6"/>
    <dbReference type="STRING" id="48709.A0A1D2MRB6"/>
    <dbReference type="OMA" id="WHVATKE"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051299">
        <property type="term" value="P:centrosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000002">
        <property type="entry name" value="Platelet-activating factor acetylhydrolase ib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017252">
        <property type="entry name" value="Dynein_regulator_LIS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037190">
        <property type="entry name" value="LIS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056795">
        <property type="entry name" value="PAC1-like_LisH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24951">
        <property type="entry name" value="LisH_PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037647">
        <property type="entry name" value="Dynein_regulator_Lis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109925">
        <property type="entry name" value="Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="4 12" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="PAC1-like LisH-like dimerisation" evidence="13">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="145"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="287"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="329"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="363" mass="41552" checksum="B15AF5486D17EC43" modified="2016-11-30" version="1">MVLSQKQREELNRAIADYMNSYGYHESLEIFLKESDLPCDLGDKKYVGLLEKKWTSVIRLQKKVMELEGKLEQAEKEYLAGAPTREKRSPSEWIPRPPEKFTLRGHRAPINRVAFHPVYSLVASASEDATIRIWDFDTGDHEKTLKGHTDSVQDVAFDNTGKWLVSSSRDKTIKLWEVSTGFCVRTFDGHREWIRMVRPNQDGTLLASCSNDQTIRVWVTNSRECKMEFRNHEHVVECIAWAPPTAADPICEGTDNKKSPGPFLASGSRDKTIRIFDIGSQSCVMVLVGHDNWVRGLTFHPSGKYLLSVSDDKTLRVWDLANKRCLKVLEAHSHFCTSLDFHRSYPYVVTSSVDQSVKVWECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRI2</accession>
    <name>A0A1D2MRI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Thioredoxin reductase 1, cytoplasmic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11180</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000663">
        <property type="protein sequence ID" value="ODM95501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRI2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRI2"/>
    <dbReference type="OMA" id="HNTIGVH"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000004">
        <property type="entry name" value="Thioredoxin reductase 1, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000012">
        <property type="entry name" value="Thioredoxin reductase 1, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9" id="KW-0274">FAD</keyword>
    <keyword evidence="3 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="63"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="10">
        <location>
            <begin position="284"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM95501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="412" mass="44951" checksum="2444364E9B812AA2" modified="2016-11-30" version="1">MRSGSSKAKSKSSNLRCCHPFPKGSTWGLGGTCVNVGCIPKKLMHNSNLIKDFLRTLPALEISGQCIVIAVGGRPRYLNIPGGTAKDALCITSDDIFSLPYAPGKTLCVGAGYIAMECAGFLAGFGYEVEIMARSGILRGFDSTVVDLIESNISSRNVKITRSTNPTKITLANDGEPPLLNVEYENLDTKTTHKEQYNTILIAIGRSPCTPGLNLEKVPKIKVDADGYIITDVTERTGYPNIFAIGDCAKGRPQLTPPAIRAGHYLARRIYEDGFDKIVDYSCIPTTIFTPMEYGCCGMTEEEASQTYGAANIEIYHKSASPLEFSINKRDGEAIYAKLVCLKKRGKEKVIGFHYLGPNAGEITQGFAMAVKRQALKDEFNELIGIHPTCAEIFTEMHITKGSQQTYIQTQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRJ4</accession>
    <name>A0A1D2MRJ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000633">
        <property type="protein sequence ID" value="ODM95697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRJ4"/>
    <dbReference type="OrthoDB" id="2152335at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="236" mass="26340" checksum="83A69BD946B37BA3" modified="2016-11-30" version="1">MSSMQLVKLVAPTPIVGPFRRQDAPYIRPTKFVPVLDYFSSSDRDVSDQEQDGIKAKWEPGKSSYEQDQQLSKWRKVTYDVPPSTRKMRRDSLSSLVDHSMQEMNKQFKSNISQFSQGLCYNHMERKIQSDLGGGASEQAELPSVKGCGGDESIAEDGSGANPLIYFKYDFGYEFGIANPRNVRASSEPPAKALPSNQSRKSKRPTSLIADAGEDEDDDRPIELPIIHETTTSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTT2</accession>
    <name>A0A1D2MTT2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000532">
        <property type="protein sequence ID" value="ODM96510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTT2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11739" checksum="B1427D9B364D1904" modified="2016-11-30" version="1">MERKGDKATYQNQYAPVENNGMVSYSGGYSVDDSFAPDSPFFPFTGSRRIGGPPQVPGNVKRKKDGMDPSLDPDGQQNWVSGKFNISTFVAKFCRLPMRQNYSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU40</accession>
    <name>A0A1D2MU40_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HTH-type transcriptional repressor PurR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000552">
        <property type="protein sequence ID" value="ODM96324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU40"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="13291" checksum="75061EC98EA4D895" modified="2016-11-30" version="1">MRHSYSIPSISQNSLNDNMSISLPVLTFIFRNISNGTYRATALIPFVSGRPSTSRTAFVTLLNPIFSRVEASKVIKSFPLMSELRSISYKQTNNKPNCSCYGIKTKPTLTVSDSPTETAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU59</accession>
    <name>A0A1D2MU59_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aminopeptidase</fullName>
            <ecNumber evidence="12">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_10056</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU59"/>
    <dbReference type="STRING" id="48709.A0A1D2MU59"/>
    <dbReference type="OMA" id="RIRANIM"/>
    <dbReference type="OrthoDB" id="5868348at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000006">
        <property type="entry name" value="Puromycin-sensitive aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12 16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="15">
        <location>
            <begin position="39"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="13">
        <location>
            <begin position="249"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="14">
        <location>
            <begin position="562"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM96620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="864" mass="98551" checksum="5F236390BA8B0064" modified="2016-11-30" version="1">MITVPKHRLHKSVIPQKYFLTIVPILDPGFEDVLGAQWEAPGSVLVNAFAAKATKTITLHAKNITIHNVTVIHKSEVIPVRNVSQHDRFSFMKIHLSQSLIPGDLYLINISFTSYVSEVLNGLFRSSYTNEDTGEQEWFAATHMEALHARQMFPCFDEPNLKAVMQAKIGRREDYVALFNTESTGNETMQGVDGWVWETFAPTVQMSTYLTAMIVAKFQYSEAPGKLLPETRVRTYAPSHYIKQGAAVYSAEVAERILSTYGEYFKEKYPMKKFDCVAVPSFLYGAMENYGLSIFRETLLLHFNHSTESKRYIVTNVISHELGHQWFGNLVSPEWWTNLWLSEGLTKFLEYIGMNATIPEFEPWDIFISESLQLGLRLDADPRTSHSLKIDEDAWLMKNEMEWFDDIAYKKGGSLIRMMQGFLSEPVMRKGLSRYLARMKYKSAVQDDLFADCDKEGQLAHKLPENTTLKDVMSGWTLQAGFPLLRAKLNGENNVTVSQEKYISIRGSGSERKMRWFIPVSIATARHPNFDPEPEFWIRNNETSVELRLPANSWLILNAGNTEYIPIQNALNLTKYMKDHAETEQVVWTSLLSMMKTAFKLFKETDDEFTPLKKYMLPRIEKAIQATGGFDAIKMNSTGMPVLRHAQLLDWACNLYSRGCIQYAMELVKSWKNTGQLTVPKDFQTVIFSAAVASDSSGEIFDFIKQQYKTAEDTLKDQLLTALSHSQDTGRIKSLLNEITKRDLLGDNSEALVLLQHLGSNAKAADITLQYFIENFATIINHFGGINPIVVAANAMAPHLKSLSGLFFIDQLVQLNTELFKTSLAPAVSRIRANIMWFDDFGEDMLEFFEQNSIYQRDFYKRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUC1</accession>
    <name>A0A1D2MUC1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein rolling stone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000521">
        <property type="protein sequence ID" value="ODM96606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUC1"/>
    <dbReference type="STRING" id="48709.A0A1D2MUC1"/>
    <dbReference type="OMA" id="SYFAPGH"/>
    <dbReference type="OrthoDB" id="419711at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049352">
        <property type="entry name" value="Rost"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21534">
        <property type="entry name" value="Rost"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="288" mass="33434" checksum="BF2D9E645E5371DB" modified="2016-11-30" version="1">MAKNCLTKIKDDFNLNGITNVYFWKSEWESFHPYDKHTPVSPYFLAYRFIYFVYFFGSTIEIFTCDDGSNRFFFLFLTNQTFTIQLLYASAAFLYVLWVFLKQTWTRGCKGEDDMIPLTGFHLNDDDYQLPFACKALWISISVVQVVPYIVSGLYWVLLANDTTFTMPCDRIDNLLVHAFNSVMALLDSLVIAVPSRISHAVFPFAYGVFYALFTFLYEEWNGLYANDRGFIYPVLDWRANPTGALITSTGTIFGSVLLHLIMCWGVFRLRTAVKAKCEELYSMYFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV32</accession>
    <name>A0A1D2MV32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative phospholipid hydroperoxide glutathione peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09782</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000492">
        <property type="protein sequence ID" value="ODM96903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV32"/>
    <dbReference type="STRING" id="48709.A0A1D2MV32"/>
    <dbReference type="OMA" id="YNADFPM"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF134">
        <property type="entry name" value="PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="67" mass="7595" checksum="25EBBC3B33007DF9" modified="2016-11-30" version="1">MSSKIDVNGDKAHPLWKYLKSKKGGTMGAFIKWNFTKFLIDKDGQVVERCGPPTDPLDMEKDILKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVW0</accession>
    <name>A0A1D2MVW0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arginine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATP:guanido phosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000463">
        <property type="protein sequence ID" value="ODM97213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVW0"/>
    <dbReference type="STRING" id="48709.A0A1D2MVW0"/>
    <dbReference type="OMA" id="SGSTHIW"/>
    <dbReference type="OrthoDB" id="432281at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.135.10">
        <property type="entry name" value="ATP:guanido phosphotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022414">
        <property type="entry name" value="ATP-guanido_PTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022413">
        <property type="entry name" value="ATP-guanido_PTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036802">
        <property type="entry name" value="ATP-guanido_PTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24172">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24172:SF4">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00217">
        <property type="entry name" value="ATP-gua_Ptrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02807">
        <property type="entry name" value="ATP-gua_PtransN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48034">
        <property type="entry name" value="Guanido kinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51510">
        <property type="entry name" value="PHOSPHAGEN_KINASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphagen kinase C-terminal" evidence="8">
        <location>
            <begin position="341"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="154"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="576"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="344"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="493"/>
            <end position="497"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="530"/>
            <end position="535"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="596" mass="67777" checksum="D2EABDF8DF7FCBEA" modified="2016-11-30" version="1">MVLKGHGHELTTKTSENPEIQEFLNNVPAYMAKINSIHSAAYTGNMRDLQSLLDRKRLAEAQDSRGRGPLHHAVLGNAPQVVRYLVNGYPHCLNLMDHNNRTALHYAATLPDSGAMYKVLIQAGGDPNVRDSQGNTPGIYLRRKDLLKMAELVGSGTPAPSATKSKAVDTWERPATPYPETQSTVIHISPPASPPGEQEQEQMELPVSNLSLLNSFYLEVLSKESQSIWSKTWKKLTSGNNSTEVANKYVKRYLTPQVFHKVKMRCTPRYASTLLDCIKFYPQFFIVAPDPHAYTSFSEVFLPAIFDANGVKPFTSHPDMVLQGATALSQDYPIVDLPSKFVQLVRVRVSRNIRPFAFIPIMKREHLYEIQKLIRRVFESEQFEWFDLETLEKDERDEVVENRSVWFPEATKISRFWPKGRGFLANESGSTHIWVNAEDHVDVVVQSQYGNLRPVMEVVQSTIDMVQEHCDFHFNSQCGFLTVDPFRCGTGLKITFRVRLPNLMQNRSYFTQRCETLNLSLKWKQKYKYFGSSSEVSPEDWVEVENIKTCGVNENEIVDHVISSVTELIKDEEDKARAIDRATTKKKEHGTPTSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXT9</accession>
    <name>A0A1D2MXT9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000408">
        <property type="protein sequence ID" value="ODM97820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXT9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00021">
        <property type="entry name" value="PRORICH"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="16919" checksum="E53E7807C45AD687" modified="2016-11-30" version="1" fragment="single">DRTGTGKTDRSEDEFLDANDLEEWVAEIYHKTVFELPSNTMSGCPPCPPCPPDPCADPCPPDPCEPEPDPCKPEPDPCEPVPDPCEPVPDPCEPEPAPATDPCPPDPCEAPASPPDPCKEEESKPAEVELPAPPCNCRIDNYPMNLTTEINKNDKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYI8</accession>
    <name>A0A1D2MYI8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Caspase-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08628</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000385">
        <property type="protein sequence ID" value="ODM98052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYI8"/>
    <dbReference type="STRING" id="48709.A0A1D2MYI8"/>
    <dbReference type="OMA" id="EHICNDI"/>
    <dbReference type="OrthoDB" id="6097640at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1470">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002138">
        <property type="entry name" value="Pept_C14_p10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901">
        <property type="entry name" value="CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901:SF8">
        <property type="entry name" value="CASPASE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00376">
        <property type="entry name" value="IL1BCENZYME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50207">
        <property type="entry name" value="CASPASE_P10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Caspase family p20" evidence="8">
        <location>
            <begin position="338"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Caspase family p10" evidence="7">
        <location>
            <begin position="476"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM98052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="570" mass="65029" checksum="D3E30EFDCD097246" modified="2016-11-30" version="1">MGPKSSNNKNKKAAIKSKQKPKSAIKRVKQSNSKSVAGSSSSKTQKSNRRLKKQTPVKVPVKFDVLDSKEIKNKECGDYVKMLLKHKGKTIDALSWKHYATENFKMLKKGWSYEVEGQIKQQTKSSKFQQYITEQVQRNKNFSNLSLRNVTFESAEIYRYVGCGTCRTSLVSRKLCLTCKKRGLSADKKDLFMILRNIHIRDSTGSLKNVVCFDNECKKLVGKNACDFSSDEEAKLLLEKSFYGATLNLKISSARFSTGKTKTTWSEHICNDITRTSEPVTQSYYTEIYKPEVSEPDDFVIEDAPSVANITHLFASASIAINDIREEIDEVYNLNSTPSGHVFIINNRNFPVSEPRKGSEKDVENLESVFEALNFAIFKDEDLTVEQFQTRLKNFKKRLVAQNANACVLVVMSHGQLNEIEMTDGKLVDVWKDIISEFSDLNFPEFSDRAKIFIFEACQIYLTHGFMQSISSNFSPVHSDMMLCFAAIPGHYGYRSKTDGSFFITVLCNVLQKYAARVDLVEMLNMTQRLMKKSKFIARSGTKEVFKEQMCYHISLIFKKFRFKTTAVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZV0</accession>
    <name>A0A1D2MZV0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000350">
        <property type="protein sequence ID" value="ODM98481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZV0"/>
    <dbReference type="OMA" id="KIARCCS"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="42320" checksum="536B64BB7B0A3192" modified="2016-11-30" version="1">MTTKNMQAGTRLQDTNGEIGFPLHIAHILNPGKEIKFSEILCRLIHVCMIEAGFVPIIDSEPDFTVEVLCDMTREESVPQLIKRLQDIIVKKGSLHNVLYRAIVMKEFAPPLEPAETFVNRDDKETKGSPTEQSTDSIPLEKKPDSVDVTSSRSLTSKESGDGSLVSNPDSISQLVSSSRQKAYSENIAVSIIHEDSEIFVVANGPGTHRNSQISVYEFSNYQMLPSFAKAREYLKMIDFKATTFATEVKRNFCYQIMDDMDALSFDIRSLTWMPHEVIVKIARCCSSLNVIRLRNTCSNIRGALGPTNAQFWKYMIKKDFPHHNIDILNSDPAEDKYFRKYTEIYRMTFRPLRRGVGLHRPPYYYMQYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZV1</accession>
    <name>A0A1D2MZV1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000375">
        <property type="protein sequence ID" value="ODM98185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZV1"/>
    <dbReference type="OrthoDB" id="8882621at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="727" mass="78571" checksum="8F7AA81C8DF19D5B" modified="2016-11-30" version="1">MYVEQTSASEVSKPEIEKAEPGAIEQEKIQQSLTLPQITLAVGTEAESDDTSSHLDSKPGLKSELIQDPPKEERVLTNEVSDVTNSSVNKEESDELKMKDTEAFQAVELRKKKEAPQVIYQYSGPPTIKMASWNERPRRAVSVKKDEDYIMGFGQQDPNAKSSNPARIHSFHGGPVVSMAQLQTDNDHVSGKNNRESSPTPTVHVKGWSAALNATNVTPNSTGAVRSVLSAWKQKMEETEKEKSKPKEGPPAEIDIYGSENTEKVQPTPAPVKSTPEPVKIVESTNKTVQRVSESQIEKQAKPVVVEVKAATTTTKPEPKVVEKSKTLGSSFRSEKPMVFSMSSMDSNSNTLPKTRPVTIHNPSDVVDYKSNPATSTVEITSGSTLQERKKFFQGIQPVQNGKEAPIPATNLKSNIAAIQKVFEKQRTTKIQQMGSQQSLYSEGTISPVSSLQRNDSMESRKSNNNNNNFQRQNSIESHASDSSSVVLRVSGKASPQLSSTEMVQKLFGRPNNFNLDASRRTPSPISSTTSTLSSSTSYERFTPSPTVVDGPNNSVRITTGGYKPPKMQPSSTTTPAIRSVGNKAIIMVNGAEGSKTANKTEKTSVANDIILHEKNSSNSAKLAPAPAKQVPVTTKKMSIESVGSQKSANSNGIPPPPPPPSDGPTTPSLNSEKLKTTPVANNSRSSKPLTPTTPTSPSPRDEIFNAIKNSNGNFGLKKTGSSILLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N069</accession>
    <name>A0A1D2N069_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000340">
        <property type="protein sequence ID" value="ODM98601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N069"/>
    <dbReference type="STRING" id="48709.A0A1D2N069"/>
    <dbReference type="OMA" id="PYYKACP"/>
    <dbReference type="OrthoDB" id="6339724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006631">
        <property type="entry name" value="DM4_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21398">
        <property type="entry name" value="AGAP007094-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21398:SF6">
        <property type="entry name" value="AGAP007094-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07841">
        <property type="entry name" value="DM4_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00718">
        <property type="entry name" value="DM4_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="232" mass="26300" checksum="4BF7C7649277E9B1" modified="2016-11-30" version="1">MSFNSNENDDTESHVLQKGRTRRMLWLNKKRQVIFPPDTSLSITPMLAFPMFKQSSTWVAFENLQITLTFFILFQGLGWTSDDNAWPLDISSLFPNMTSTSTMEASRRNGYCHRKNKFRNGGCGRSIPIMSLPHHTPGGERATLFPHLERLLSSFGIDGRACLQRTVCEVHEVPLKNGFGMLGEFLTMLFSVSESIFAKSHLPGYLSAEKAGKYGDCSRFYKKCPYSLFTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N087</accession>
    <name>A0A1D2N087_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Guanine nucleotide-binding protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08022</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000337">
        <property type="protein sequence ID" value="ODM98650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N087"/>
    <dbReference type="STRING" id="48709.A0A1D2N087"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000002">
        <property type="entry name" value="guanine nucleotide-binding protein G(Q) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003977">
        <property type="entry name" value="Guanine nucleotide-binding protein G(q) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000654">
        <property type="entry name" value="Gprotein_alpha_Q"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF329">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00442">
        <property type="entry name" value="GPROTEINAQ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 10 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="149"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="174"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="268"/>
            <end position="271"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU369122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="354" mass="41288" checksum="1E7DBA4E651D97B4" modified="2016-11-30" version="1">MSCFLSAEAKEQKRINQEIEKSLKRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSEEDKKGYVKLIFQNIFMAMQSMVKAMDNLKVSLEHDNLQEKFDEIKDMDYEEVTTLEGGWVETLKNLWNDKGVQEIYDRRREYQLTDSAKYYLSDLDRIGEPDYLPTEQDILRARVPTTGIIEYPFDLDSIIFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESNNENRMQESIALFRTIITQPWFASSSIILFLNKKDLLAEKILTSHIGDYFTEYQGPKLDDVAAREFILHSLYLSQNPDPDRMCYSHFTCATDTENIKLVFCAVKDTIMQNALKEYNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0J6</accession>
    <name>A0A1D2N0J6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium/hydrogen exchanger 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_07878</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000321">
        <property type="protein sequence ID" value="ODM98799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0J6"/>
    <dbReference type="STRING" id="48709.A0A1D2N0J6"/>
    <dbReference type="OMA" id="GYWCARI"/>
    <dbReference type="OrthoDB" id="441412at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF86">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="834"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM98799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1059" mass="118637" checksum="0344185A9ACD8055" modified="2016-11-30" version="1">MEPQDWFWPDTHGQELGDSGNQNSDVDIRPIVVHSSGGHEIEYDDEAEFRNFCQHQELVRNDPQNETLLKQCSETKPGEFVKDDLIMLFSLGIMMCWGVLVRVVLRRFHLPFPYTVVLMLSGFAFGFLSKHFCDELHSYTAIVRIHPEIILLTFLPVLIFESAFSISVHTFTRSAVSILLVAFPGMLISTFLTSGVCMYFFESYNWTFPQASLFGSVVSATDPVAVVAILRELGAAESLSVMIEGESLLNDGVAVLLYEIFVEIVQEPEMLADWLPLTLHIVTKFCQIAIGGTIFGCFAGKITVFSLNNVYNDPTCEIAITICSAYLTYFIGEELLGVSGIMAVVALGLTLGSERTCISPESEKPVHHFWEMLGYFANTALFVMVGILISEVALVGVTKTDVWYLIGLYFQLTVIRLAMLTLLSPLLSRLGYGMEWKDILVTAFGGLRGAVGLCLALEINENPNLCDKDKLGPKILFHTSGIVFLTLVFNATTTKKLMDVLSMTKITLGSASDMENAYYLLMKTRKTAISAFKSDRFLVGSVWTVVSGSTKIENPYREEIAKAIAEASRAFGKVLSENIGLPLPNTIRNNKVMQDPRLHIMSYQEVHEEARRRIVHMIKSASWKQFQQGLIHADAARALVSHCEKVEDTPLILVSITELAKSWEPGWLLTKISELGTDAKFNCLQTIFQKISQYFIIERIHLAYEISRGFVSSMDTVIKLIPLLPDTPETLEKFKRTLEKERMLIFQELGPLQKLQPGVVQAVKTRITCRTVLNQMREGVKEIKHEGLIDHEEAVVLELELEKQLKEMNAKIPHSLMVAPPISFIHQLGWIDGDEELKTYLVENASFMIFNYGDTIYSLDEPPKGIFVLVNGLVKVEYSPSSSIVESFEQYGAFPNSEVLTDLTFKGKTADILTQGALIGEIGFLKNVPRAATVTCGSYVTAYYFSTTALKTGMSIFGEGENKESLEAKIWRSWGFRVATALLQRLPAYYEWSLEKIQMHLEPSVVPVMDKFETFEIGDNIADVIVIEGYIQNYHTKEVYAAPCLVPRYCTHITSVTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Q3</accession>
    <name>A0A1D2N0Q3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000317">
        <property type="protein sequence ID" value="ODM98842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0Q3"/>
    <dbReference type="STRING" id="48709.A0A1D2N0Q3"/>
    <dbReference type="OMA" id="ACLMNKE"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811357" description="Carboxylic ester hydrolase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="37"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM98842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="565" mass="63703" checksum="9FB8379E9395EFE8" modified="2016-11-30" version="1">MNIQLTKLTPSSCWLLFTALFHIQSCGVCAEKTYDVDPIATVTQGQLRGKFGESRNGKDYLEFLGIPYAQVTETFKPAAPPIKWDGIREATSFGDRCMQFDKNTHKVIGSESCLVLNIYRPMEMEKVLPCLVYIHGGAFMFGSGEDYGPQYFMDEDIILITFNYRLGALGFLNTGDEMYPGNLGMKDQVLALRWIRDNIASFGGDPQKVTIFGDSSGSASVSYHILSPMSRGLFSNAISSSGNSLCPWAFVDNPKSVAKRLSFSIGCPTKNPRYLVACLMNKEPSEIGWDDDPIVPFAPSIEDSRKVLGTVFLPDHPISMLESGNFNRVPWITGVNDQEGATLYSAIILNSTELTEEFNKNWHKIAPFALGYQESEESDLEATNDIRKYYFGTQPVGLETRDNLTNMFSDRNFFQCTKTAALLHARYSPVHMYYFTQTGEMSWLDIFKIPKDFGYHGVAHSDPLQFFFKLHNFPEIKAESTFSVFSQRLVKLWASFVESGKPTYTWGEFLEWNPMQLSELSGLSPVKYLQLDGSSSRVIMEPFTERLDFWESPPINLTNIHIAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N270</accession>
    <name>A0A1D2N270_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ejaculatory bulb-specific protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000305">
        <property type="protein sequence ID" value="ODM98995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N270"/>
    <dbReference type="OMA" id="VNQCANC"/>
    <dbReference type="OrthoDB" id="6355718at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2080.10">
        <property type="entry name" value="Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005055">
        <property type="entry name" value="A10/PebIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036682">
        <property type="entry name" value="OS_D_A10/PebIII_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11257">
        <property type="entry name" value="CHEMOSENSORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03392">
        <property type="entry name" value="OS-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100910">
        <property type="entry name" value="Chemosensory protein Csp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904912" evidence="1">
        <location>
            <begin position="21"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="19245" checksum="71465D94D06AB255" modified="2016-11-30" version="1">MTRFALLCLVVALSISEGYAASLRFKRQLIPREFQNINIENYLKNERAVRFQLKCIIDDGPCDRIGKYLKVTIPELLVNQCANCDMAQRERAGKLVSHIQQNFPEDWERAVRKFQGGLVKPEDAARLESVLGVKLDPKLVGPMDTSLLLHLLKPVQLLRLLQLAPSCEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2F3</accession>
    <name>A0A1D2N2F3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription elongation factor SPT5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000280">
        <property type="protein sequence ID" value="ODM99463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2F3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="314" mass="34398" checksum="4C33B2D4E94A3CDF" modified="2016-11-30" version="1">MALLISKQSSSPCFECNLKTISLAGSILYGLIHSNNMLKALRTKIVDKLSAFDVPQQNSPAFATSYSPQQPAVISTPTELHQTPTHPVPSTASNPQEPAPPVEYFHQPVPQVQYQPLPVQAPQSQDECEPCSICGCPISSGVRLFSIVDIVLCLVFLGTQLGFVSSLINNARRGNSTSSTHALPRGPVTSLVIIAEVIAIVFRIALGCLCLVCGVFRNRRNLCKLWIVCALGHGLVELGFNLYESYYSQRDELWIKFGLVVILGTIYTGYSIWIVVTFIQWLNTEAAAREAAAVQRAYAVVSRPLNMVMNSMRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2I4</accession>
    <name>A0A1D2N2I4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Blastoderm-specific protein 25D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000277">
        <property type="protein sequence ID" value="ODM99493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2I4"/>
    <dbReference type="STRING" id="48709.A0A1D2N2I4"/>
    <dbReference type="OrthoDB" id="5799458at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="29670" checksum="B690BB686EA20547" modified="2016-11-30" version="1" fragment="single">ISQLEQEISEKKAAFEKENGDLKASNSELENSLELLKDEYERCEDYWHEKLHEARELYEQDKADMDEKFHDLLQKIKEYEDLVMHPMVNERLPPIEERASLERQVTDLEEECVVLRKELTSVRMDQETVINTYQRSYENKLKDECANLEQQVSALSKKCQEYENRLSSLAEEERSTVEENGMVDMMKERIKQLELQLKSQEEKFRQTVTQLEATLKEREVLYKKSIPDVSDCKKKVKIFSTWMDLSRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N373</accession>
    <name>A0A1D2N373_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Histone-lysine N-methyltransferase eggless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_07174</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000275">
        <property type="protein sequence ID" value="ODM99504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N373"/>
    <dbReference type="STRING" id="48709.A0A1D2N373"/>
    <dbReference type="OMA" id="SMIRINI"/>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046974">
        <property type="term" value="F:histone H3K9 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070828">
        <property type="term" value="P:heterochromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051516">
        <property type="entry name" value="SETDB_methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041292">
        <property type="entry name" value="Tudor_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041291">
        <property type="entry name" value="TUDOR_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024:SF1">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18358">
        <property type="entry name" value="Tudor_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18359">
        <property type="entry name" value="Tudor_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 19" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MBD" evidence="18">
        <location>
            <begin position="506"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-SET" evidence="17">
        <location>
            <begin position="631"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="16">
        <location>
            <begin position="707"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="775"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="779"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="853"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM99504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1000" mass="112134" checksum="B3A24C7F1444321D" modified="2016-11-30" version="1">MMQLVRNKENLFGIPVEIQSSQAVVVDLDSPVGSPNSKSEVPEGQVGSMPENYIVTLGRLEKVLTGKLKKFSLESQVKQCTDTVNKEMDDLIGCVDIDERGIITAAHNSNWQQYQSIDGLSRIAARQLSVAVSNIKSLENAAPAVSAGGTNRSQLIFSKPTPGQEVYAMSKHSLFYWLPAKVLKVNLNSRPSVYTVQFQQKVKPRSKSIDDADMYVKELTGRQVAFKKPTSAQLPIGCRIIAKFKDLLRTDGEVDGMLYAGVTAEVPKNSNKQRYLIFFDDGYAQYVSQADIFPIVEASPDVWLDVHTNSRDFIRDYVEKYPNRHMIRAQINAGFNVELNAYLIKWGTISEIGRWLPAQIVEVDGSLMKVRYLRRNPEGVQFEWIYRGSTRLGPLFSRIKSLEAKPVTTCARRHTYSARSHISFEVNQDTVEEDSKIAKKITGTGPLPHPTGQTVRVQNGMIISTILETKGSMIRINIPDNCPTSRTYVQHNCSPKCAYPYEEDKYRRVSPLAIPFYLGWARQLTKTDQVFYVTPCGVRCGSYKEIHSYIVQTKASIPIDFFSMESIIDCLNAFEPERKIESVRDISYGKEWTPVAFVNSLDHDLPVYMEYITARVKGKGVNLNDDDGFLTCCDCEDDCEDKEKCSCWQMTMSGISFKIGEMEGEKLQGYENRRLKGHVLSGIYECNRNCKCRSTCFNRVVQNKVKWPVQIFKTFAKGWGVRALHDMPQGSFICVYTGQLLTDNEANEKITRKTSPTLNVKNLVPEALLGLRRQLQQRNEIEPKKQDVAKKSTGGKVQQQVTQRAHKSTGGMVRRNGDDSSSSTSSIPPTRPVARKSGSKNGSGSTNNGGGSKKPSPNSSGVPSPALSKRSSKDDSDSDDDEGTGHAYSSFYATTKDEGKPTKLTLREYFGKDESVYIMDAKSMGNFGRYLNHSCDPNVFVQNLFVDTHDPRFPWVAFFTKKDVKAGTELTWDYNYEIGSVPGKTLYCYCLQNGCRGKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N481</accession>
    <name>A0A1D2N481_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000234">
        <property type="protein sequence ID" value="ODN00088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N481"/>
    <dbReference type="OMA" id="HTSESWE"/>
    <dbReference type="OrthoDB" id="10685927at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="704"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="535"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="646"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="705"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="776" mass="88098" checksum="A3CF509628D6E083" modified="2016-11-30" version="1">MSMNPQQGEVQGSTTSTKTEEGRFSNGRYAKTTQNATFANSRSTSTSSKRPMSSRIPHATTRIGHIRGPWIPAPAKATNVTGEPIQHQSSHPAFVASSTSSYGSVTPRPKSYVATLEKGNTSSSRNKMKWLSQHNQSGSATTATQKHHKEFRHVRKSTSKVKLATKHGSRHIVSGGYKLQSKDSLVDVTACLQAKRAEVMILWEKLLLRDDPQLLSQIEKTNRLALEAAEEVESLRKTIHDFQKKDDGLSESDLAKLEGMRGKVLEKVREFEEADNELQSSIVRKSPSKISLVSTVSKKSQTDMHNDDLTVGQQTGIPPTTGTQLIIARKSHSSPSVKELVFLKEKSPNFAEDSQSEEERMDFATKHQHLSLPKSVDAEVSAVPSMDDLTRLKLLYDEALNFPPINNITESRSNVALHTSESWEKQSQSNRTVRFMGGQPQEVLPESTTCDGLYRQKISSLQRKLMDTEQEMEELKSEIERIESDANFRSQYPSRQIRQFRSNPEYLHMVEQRLHETGEVKVQLQTQLQSNQKSLHEEKELNKVMKKEADELKERLRTVENSKDILKSKNSELEANNMQLRKELESITRQMAEMSSELRITKEREANACLLNTSPKLAWENEKLKLQCSELTDQLGQSQRIIESLKKSKAKQAIRLNERIEELIEALNEVHDHKRQLCDTIRNLRKSYYRLFPDDVYHVMCQKSSHSKKSKTRKKRPAVESKIEQQTAWRTGAGGFQDNLNSSDVQSKAPMTAYQTSLNLLDLTETKFELEDDHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N589</accession>
    <name>A0A1D2N589_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">F-box/WD repeat-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000210">
        <property type="protein sequence ID" value="ODN00392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N589"/>
    <dbReference type="STRING" id="48709.A0A1D2N589"/>
    <dbReference type="OMA" id="PANGHCQ"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22133">
        <property type="entry name" value="F-box_FBXW7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000133">
        <property type="entry name" value="F-box and WD repeat domain-containing 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="74"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="183"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="225"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="265"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="305"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="345"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="385"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="428"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="467" mass="52136" checksum="499E7B27675AD1BD" modified="2016-11-30" version="1">MDTTESSSSLSDGSSILSTIPSTDYPAPRMGEWLQIFSNWSNPERLMAINELVGVCGTSEVRHMMELIEPLFQRDFISLLPKELALYILSFLDPRDLSRAAQTCKYWQIISEDNLLWREKCKEAGIGYFSAMSSRVHKRRSNADLSSDGDTDLSNTNWKTEFVHNQNIEMNWRSKDTRNPSLLRGHDDHVITCIQFSEDRIIVSGSDDNSLKVWCVTTGKCLRTLLGHIGGVWSAQMSGTTIISGSTDRTIRVWNAETGQCLHTLHGHTSTVRCMKLHGNRVVSGSRDATVRVWDVETGECQHVLVGHLSAVRCVQYNGHLVVSGSYDFSVRVWDPESELCLHQLSGHANRIYTLQFDGIHVISGSLDSTIKVWDVKTGTLKHTLTGHSSLTSVMEIRNNLLISGNADSTAKIWDISTGQCIFTLRGLHKHSSSVTSLQIVHNFVITSSDDGTVKLWNIRTGKSLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5T8</accession>
    <name>A0A1D2N5T8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoinositide 5-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06111</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22764"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="EC" id="3.1.3.36"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5T8"/>
    <dbReference type="STRING" id="48709.A0A1D2N5T8"/>
    <dbReference type="OMA" id="HPCHELR"/>
    <dbReference type="OrthoDB" id="1925875at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048488">
        <property type="term" value="P:synaptic vesicle endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015047">
        <property type="entry name" value="SYNJ1/2_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08952">
        <property type="entry name" value="DUF1866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01165">
        <property type="entry name" value="DUF1866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="7">
        <location>
            <begin position="120"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="999"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="999"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1088"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1111"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1154" mass="129243" checksum="1F14412DECA139E1" modified="2016-11-30" version="1">MALGKPYRVLCLNTPEKFSIILKHRNKDDALLFESYAVAQISAPEVQVLRKMYTESIESYYGCLGVLRFHTEDDLLMFLVLVKGCVSVGKICECEIFRVTETTFINLRGPSSEDDKIAEIKKVMNSGTFYFSWGGTAGQMDLTLCEQKRNATKETDNRFFWNRTMFLHLLRFGIDCNEWLLRITCGSVEIKTVYAGAKNVKTAVVSRLSCERAGTRFNVRGTNDDGHVANFVETEQMIMTDNEISSFLQTRGSVPLFWEQPGVQVGSHKVRLSRGPEAACSALDKHLYLLRERYGKQAIVNLLGTNMVGSKEGEAMLSSLFHSQHVGNPDFVDMPHILFDYHQEVRGNRGLEKLEFQIKKYLDQYGFYHNKDGKVTKHQLGTLRTNCLDCLDRTNCVQTFIGVKILEQQLNLMGLIDKPQSQVRFEEVFRQMWVNNGNEVSKIYAGTGAIQGGSKLMDGARSAARTIQNNLLDQSKQEAIDVLLLGHTFNTELTSYARSLLPAHYLHAPPSVLRQMVKRWEDYTTPKTLRVVIGTYNVNGGKHFRSVVYKDLSLSDWLLDAAKIARSSSLVSIEDEDADVETPADIYAVGFQEMVDLNASNIIAASSENQKAWAEELGKILNRDNGYCLLSTLQLVGVCLYVFTRPELLPHIRDVATDSVKTGLGGATGNKGACAIRFVVHSTSVCFVCSHFAAGQHQAKERCNDYAEIKKNVLFPMGRTLESHDYIFWCGDFNFRLDTDREEVKDLVSRQEWPLLLKKDQLLMEKEKGNVFDGYEEGEISFPPTYKYDLFSEDYDTSEKCRIPAWTDRVLWKRKMPLSDMSKSPPPDWNPGRCLHYGRAELKQSDHRPVVSVIEVEAFAVDEAKRDKVFAEVVKQLGPPDATIILKSDSPEVFEDEESDEVILNELSGCGTVILIRHINEEVWITFKEGFAALAAAMLETIQVGRYIVSIRLKTRDWESHLDKEMAICVNNCIPLHPTQNNNTIKANNSFSNLTVHSATTDGENIGTNRPPPPRSPMSERKVMSSEAVNRSPPSISPVDSPRKMQLSFNSCQPPPVPTRISPPETSDKGIGSAQPPPPPKRMSPTDSPKKELPIEKTITDSPKREGVRKQSSQTSSTGSGSGHSSPPVGNVPPIPPRQVGSTKGGDLLQFLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N686</accession>
    <name>A0A1D2N686_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N686"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="32470" checksum="2812F2BBAAC0463E" modified="2016-11-30" version="1">MILLKMNPKIQFQTKLLFVVLLFCVSCDSFKLPVNIKKSFESPRTQLSGESEDEPVSSDINSVSSSPGKPLKFPDASEITDFSAKSKPDENDSLPYYPVLVFNRNGFLDSKYIEETSQEHGAKPRLQRFYKHSAKLPRSKEEMIVFPGQENPSSERETSNEKNPEDYLRFSARAPETSIETGMETPEPPVISEEAKESSSINKSVNPGASKQSLESLAQIVRHLLFRITEPSPEQTTTTDLPHQTSTTPYVSDQSLYTGPKVKPNSDDGCSDGLKKTRNGSCQKPSKRLGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6M3</accession>
    <name>A0A1D2N6M3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6M3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="443" mass="50056" checksum="4E18CC78C2B60334" modified="2016-11-30" version="1" fragment="single">HMATTAKSNAFVTFTKVAGVLFLLGLRFNGINGKLTSELLNLNGSEPTSDTPTDFTTDETIIPTTEDTIETSSIKEDATITLSLWYPEHVCNLTGETKLRYRLDRQYINDRIAIHLWTCEFDNDEFIQIYTEDGYINETWRCYDNRLYSQENEPFAGSYDNSTAIRVVDDISNPVWVEASFKSNSISHSQATIVVNIYKQVYDTTDKCGSGFFDCFRAYNNYCPNCCSNENDFFNLRCILKDLQCNGRPNCGLLFNDKEESYEACYYDEPLCPTCQSFCLSWNYIITSLAIAVLFIVTPTVIVFALFHRRNVALARARLERMAQERMADMRGEFTRDSPLTDLPPSYEEVYETKEPPPCFCQAVAMEIGSEVVQQRCEDGSGNEAVLDSSENLNNNSGIQNQAFYCSCSNIGTLSQEPLPCYVDMSGSGDQNVDEVDTVEVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6R5</accession>
    <name>A0A1D2N6R5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-5-taurinomethyluridine 2-sulfurtransferase</fullName>
            <ecNumber evidence="4">2.8.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05743</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP = 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47040"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11732"/>
            <dbReference type="Rhea" id="RHEA-COMP:11733"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:87171"/>
            <dbReference type="ChEBI" id="CHEBI:87172"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.14" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000180">
        <property type="protein sequence ID" value="ODN00937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6R5"/>
    <dbReference type="STRING" id="48709.A0A1D2N6R5"/>
    <dbReference type="OMA" id="YARIEAM"/>
    <dbReference type="OrthoDB" id="3685at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061708">
        <property type="term" value="F:tRNA-5-taurinomethyluridine 2-sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="MnmA_TRMU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000104">
        <property type="entry name" value="Mitochondrial tRNA-specific 2-thiouridylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="MnmA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933:SF5">
        <property type="entry name" value="MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933">
        <property type="entry name" value="TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="279" mass="31348" checksum="A9957780AFBE308D" modified="2016-11-30" version="1">MALLNGIKRVVCGISGGVDSAVAASILKQKGFEVVGAFMRNWDDQDEDGTCLINQENDYQDAKAICDHLRIPFVEVSFVKEYWNEVFTQLIEDYEKGFTPNPDILCNRFIKFGSFYRYSMKELGGDAIATGHYAQNSLGNFLKHYSPGKMAHLRRAIDLRKDQTLFLSDICQEPLRKTMFPLGGLCKLSVRQLAKDLGMDKVSKKRDSVGICFIGDRTFSHFISKYIEDRPGYFVDVDTGRILGSIMEFTNGPLGKGVGLGAQNALIMFATEMQTLRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7M3</accession>
    <name>A0A1D2N7M3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Kinesin-like protein KIF20B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05411</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000163">
        <property type="protein sequence ID" value="ODN01270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7M3"/>
    <dbReference type="STRING" id="48709.A0A1D2N7M3"/>
    <dbReference type="OMA" id="HSFFTIR"/>
    <dbReference type="OrthoDB" id="123929at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF29">
        <property type="entry name" value="KINESIN FAMILY MEMBER 20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="12">
        <location>
            <begin position="77"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="521"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="648"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="578"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="546"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="660"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="168"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="684" mass="77451" checksum="EBB046D3D1CFE102" modified="2016-11-30" version="1">MEVDGIRSSSDNPSGSKSGVSPGQRPSYVDFSSTSGLYPSLQPFDERVIKRLDSELFNETASTEEHSVADATAEDEKLKTFLRIRPVSVQIDNARQVIAVQDCQTIVAFSNPKNTHTFQHDRSRKQTEFKFTKVLGPECGQSTVFEECVTPVIEKFLKNENCLIFSYGATNSGKTYTMQGHGTEYGIIPRTLDAIFTRINDRQYKVGNIRPHLYEAFLHLNPSEVDLLYEKRDRVITEASIKQELMHSYRLSTSGFSDKSGMTVDIIGGGGHTFDLCNLHSDSTLYSVWVSYAELYNERVYDLLDNTTFSKSKRRKELKLMQDRNGFVYVKDLTEFPVTSDEEAYKLFLAGRKNLQFAATQMNMHSSRSHSFFTIRVVSLGIGDGLVPYPKTVHRLTFCDLAGMERANQTENEGFRLKESGTINNSLTVLLKVIRLLREKQLHGKHGVGMIETIPFRDSKLTHIFKSYLTSSTHVCMVVNVNPDPFVAESTLQVLQNSAIASNVIVYRPIDMAVPQHVPDFGPQGKVIGKPPLPPGSVRRRDSDDSSAQTSSRFSTASEADEYEMTTVVAPKTLAQKLAMLEMENARLRDQLAHSEMEKQKIREDMLKMIVEERILWSNRLQQRMLTEENLNRRRLSLMKHEVMLSPASRCGRCSPPTADMEDIDETFEEENEDSNEDDSDKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N800</accession>
    <name>A0A1D2N800_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000172">
        <property type="protein sequence ID" value="ODN01096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N800"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="18262" checksum="6F7AF2B21A4B7C8C" modified="2016-11-30" version="1">MNQNQSGSATSNDIMNDWRNGNGIPVYQHFSAPSTTFVNNFSQPGVYNITIALPGSVGRMNPTITAPPSGIPSRQPGMTLGSHNQPNFGGAPSMTRPNYHHEGQIRQTTMPGTPVQGNGLAIPVGVRTPQMPRMLTPPPDYDARQMDEVFPPTPPASVVTSPVGAQPSQFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB00</accession>
    <name>A0A1D2NB00_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BAG domain-containing protein Samui</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04261</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB00"/>
    <dbReference type="STRING" id="48709.A0A1D2NB00"/>
    <dbReference type="OMA" id="HLRCPPW"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039773">
        <property type="entry name" value="BAG_chaperone_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329">
        <property type="entry name" value="BCL2-ASSOCIATED ATHANOGENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329:SF5">
        <property type="entry name" value="STARVIN, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00264">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="3">
        <location>
            <begin position="245"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="45524" checksum="6EC37B1776FB1B6A" modified="2016-11-30" version="1">MLAGFPFEDLRSGARARFDEFANRHPMFSTMRNQPPWNMDDPFGHHGFPRERNNSGSSGAGSGASTASTGEERVIPIQIIRDDAPKPPARGKSPAPPQTEPIRVAREASPQPQTAGPQRCNTEPTHPIVLEDSRNTRAHSAPPSQNGNDKFVTKVSIDTNGSKPTTTQVGGNCSKSPKPESPANNGGRSIPIIIEGRQAPVFNANVNGNCPGQSSAKEAPQPKVSRPADRSPTPPPKKQTLPRDPLAQVNAVSEEVKELEKLVDMFQGTSREEREYMLLDEMLTRCLIKLDVVEAEGRDDVRTARKDCIRYIQSCISKLEKKHPLTEKPDEEQTMETAPAEDSQPSAETEKMETGSQQLSSNQNTPPLQLGSSSETANPKSAENSTPEPSNKGEGVQTMEVDSKETQPASASGDQQPVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBU1</accession>
    <name>A0A1D2NBU1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Centrin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04204</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000110">
        <property type="protein sequence ID" value="ODN02466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBU1"/>
    <dbReference type="STRING" id="48709.A0A1D2NBU1"/>
    <dbReference type="OMA" id="NDFLSIM"/>
    <dbReference type="OrthoDB" id="343296at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF59">
        <property type="entry name" value="EF-HAND SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="209"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="27503" checksum="F9B3417DA539A6C3" modified="2016-11-30" version="1" fragment="single">HRRLSENVRESISAVLLHVNSLEDPSEVENETTGPSTRRSTRKATAESKTKEANSKLEESSQENSQQSRLARRANISSVPMTDKEMMEAVLKSKTDLTAKQKKDVVDTFRNCDRNGNGSIATSDLKVALRALGFEPRKNDIKKILEKVDKSNSGRLNFNDFLTVIEMKLAEKDSKDEIQKAFNLFDKDHTGLITFQNLKQIASELGEELNDEEILEMITEADADGDGAVNQDEFFRIMKKTSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBU8</accession>
    <name>A0A1D2NBU8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cysteine and histidine-rich domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000097">
        <property type="protein sequence ID" value="ODN02734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBU8"/>
    <dbReference type="STRING" id="48709.A0A1D2NBU8"/>
    <dbReference type="OrthoDB" id="10261079at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="5">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="6">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19166" checksum="35E0C7A88B032A3C" modified="2016-11-30" version="1">MKELSDSLKNQTLTTAPSSNGNDVEEDKAQIIPGVTQCVNNGCKVTYQGPETDLEACDHHPGVPIFHEENSHDQGGAKVIKCRNDWHQTGSHVIMYIYAKKFDPNRSEVKIITPEDCSVLMTPMKFEIKLKKAEPVSWKQLALPKEQQIIKTDEIKNEYSVGVDVLDLSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC32</accession>
    <name>A0A1D2NC32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Death-associated protein kinase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03871</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC32"/>
    <dbReference type="STRING" id="48709.A0A1D2NC32"/>
    <dbReference type="OMA" id="EYSAIYH"/>
    <dbReference type="OrthoDB" id="10518257at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342:SF12">
        <property type="entry name" value="DEATH-ASSOCIATED PROTEIN KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="44"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="658"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="723"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="833"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="671"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="749"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="765"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="803"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="846"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="867"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="912"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="931"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="942"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="980"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN02810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1100" mass="120131" checksum="E00CB1CEF13FD1EB" modified="2016-11-30" version="1">MVINNCDPEEFPTLETTSCDSRGILKLNQNLIINKSVLDELYRVDKGAPFATGLYAQVRRCKSLRPTGSQKLQPYYAAKFSPRKRPGHSQNEDCVESLHEIALLCQLKNPYIISFKDAFILDDFIVTIMEFLNLHAVSVCSTSANALPNKCSYVFDFVMIYSAPGGDLQSVIDADLVLLEKDASRFVSQLLEALKYLHSRHIAHLDIKPQNLLLMGEFPSCDLKLCDFEISRVIRPGMEIREILGTPDYVAPEILLYEPLSTVCDMWSVGILTYVLLTGFSPFGGDTDQETFSNIINEPIDFPEELFEDVSPEAIDFIEKLAVKNGRTRPNAEEIELHDWVRSYVSPSTIPDPPPLPPPPVVKEPVTATISAPPGSPIIGVCGPKKRSPRKASAMSGSSTASVSPAGRRQSARSILRACKSAYDLNKMGGKTKSREVLIEKMRIATGEPSGGPWKLRKNLSKSREQLWESKIQLSKSCEKINNNLPGSSRWASVANFPSLDMNTMKSSTSQESVISVMSTCTNVGNAQQQLDLDWQQQQVLDDTFPYSVSMPNTPPVPNFDLSHNNGYHESSPPIMSNNYGGLQSKLHSEEFTGYPSLASSNGSGDIPLQYPMTQSQATSAAIEEAQRSVAELIMTFGGRVSKKLDLKNKFEPILEVDGSEEQPMSLGDCSDNNSTSGVSSIIPTSACPNSKEKLNEHNGKQFENNAIYGYNNKLQTLAVNKTDTGQGQTSEPGSANSSRRNSRTAQQIHDEMKTERRSNRSEYHNATSTRRGSMSPPKNSDGTTLKGILKKPKQPDPPTPTSRSASEFPGSSSARRGSIPSNCFRLYEQHTISSSAKAPKRSILKNGSTNVTSDAKLSKSTGGNHSGKSGSSDRSSSRSPENTAAMKNSPPKDKEDSPAAEGKNENVSSAPPSINNNNQNTTSINRQNRPTSILITSNADNKIDTLESPRRTKPSADFTSIVITPPEKVCEQEGKPIPNQEQSSEGTSTPGSSCDDTEPAAVAIKVFPPDPIIIPKSSILLLNSGKAPDSPVAEDVTSPSPMDRELKEFLKKHPNATPKQISRGMKSQWGVVCTGSVERAKGRFESVRSKLRRGSVPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDS0</accession>
    <name>A0A1D2NDS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-terminal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDS0"/>
    <dbReference type="STRING" id="48709.A0A1D2NDS0"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140297">
        <property type="term" value="F:DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001221">
        <property type="term" value="F:transcription coregulator binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051638">
        <property type="entry name" value="CTBP_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46029">
        <property type="entry name" value="C-TERMINAL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46029:SF7">
        <property type="entry name" value="C-TERMINAL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="2">
        <location>
            <begin position="122"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="236"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="427" mass="47310" checksum="61D6BB51C0BF2845" modified="2016-11-30" version="1">MEMHLLEASRQSNHDTNAHQTYMHCLHFREKFLRKRCIRWLTAFFIEYVVKSVGFFPPVSHPSACCGKEIKIAKFNIMSFRNNFKVGNGVGATVVDNQRIMRCFSSLRIEKPLVAQLEGRKCTYEVAILKGVATVAFCDALCMREVHAKVLNEAVGVFVWDAFTLGREQLAKFKALKVIVKVGPGLTGVDLAAAGERKIAVCHVNGYGIEEAADSTMSLILDSFRMKTFPVTTSNRYATFQCVQLRGKTLGIIGLSLVARAVSIRAMALGMKVSFYDPFIGDGYEKVFGITRVDHISQLLGQADIVSLHCSLNDKSIGIINEASIQFMRPGAIIVNIKDEGLIEESALAAALHSGQIGGAALDTHNPDFNRGPLRDAPNLIRTPGTAYFSEVSVREFREAAAEEMKAFLEEGPRSLRLRYLKNSIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NED1</accession>
    <name>A0A1D2NED1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NED1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="23586" checksum="9CD17D9F30472EC4" modified="2016-11-30" version="1">MSYRYLNSKAHALTDDSRIYSASAEVLCITPEPTPRKKLRFKESPQLQTVRRFHKSSESLVDKNGQPKRSILRKSTSAAEFPGCALTSSKPKSSIYLSRERISKEPDNNLTEMVPRMENVDRTKTAVTVGVNTDVTLPPRLGQTFRRHVHVPSNWQRPQRTYKSFQEIIAAQPIENQAKLIDTINDSCKILFRPKSKFGSNLNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEL5</accession>
    <name>A0A1D2NEL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000070">
        <property type="protein sequence ID" value="ODN03545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEL5"/>
    <dbReference type="OMA" id="EAHAYTA"/>
    <dbReference type="OrthoDB" id="8250900at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905462" evidence="1">
        <location>
            <begin position="17"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="139" mass="14053" checksum="D191E16E104B74BE" modified="2016-11-30" version="1">MKAVVALLALVAAANAGLISAPATVIARAPALDSAVIKSDRLGGNFAYSVSEAHAYTATQPIIQHVAQPVAVSYSAPQVVQQVVAAPAVRTVAVAQPVAYAHQQVVAQQLVAAPAYRTVSIAQPTILAGNVPAATVRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEY1</accession>
    <name>A0A1D2NEY1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">U6 snRNA-associated Sm-like protein LSm3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM3</name>
        <name evidence="12" type="ORF">Ocin01_03140</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000070">
        <property type="protein sequence ID" value="ODN03536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEY1"/>
    <dbReference type="STRING" id="48709.A0A1D2NEY1"/>
    <dbReference type="OMA" id="NFEEMHK"/>
    <dbReference type="OrthoDB" id="29543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120115">
        <property type="term" value="C:Lsm2-8 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000007">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="11879" checksum="34E08C6AC8B0502D" modified="2016-11-30" version="1">MAEEGEQETENHLKEPLDLLLLSIDERVVVKMKNDRELRGKLHAYDQHLNLVLGDVEETITVVEIDDETYEEIYKTTRRNISMMYVRGDGVTLIAPPAKTHTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGW2</accession>
    <name>A0A1D2NGW2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 4C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02206</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGW2"/>
    <dbReference type="STRING" id="48709.A0A1D2NGW2"/>
    <dbReference type="OMA" id="CAQRHPY"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="516" mass="59162" checksum="E677222D354849DA" modified="2016-11-30" version="1">MNIDPEFQNQLLLTFGLVSVFIFLTWIVQARKRRQKNGIYNLPGPRQYFLGGIGNLLELSYKPGTIKCMLKWCSTYGPIFQVYFGPIYGIALNSAPYIQKLYGSSDLDHLSKSFMYDLLKPVWQDGLAISKGEKWKSRRKLLTHVVTFKCLKSYMTIFNREGKRLTERFDKVFDDGKVHPINETTLSAALSVIIEATLGINIFEANDVEGISEFVRNAQTYKEIATTRLLKPWLLINPIWRFHPLSIKHDKAVASLHAFARKVIEERKQSYSKERKLLADSPEDETEKVGKSLIEELIEANIPDEGIVEEVMTSIGAGYETSGITLHFLLFFLALNPEHQELCREEADYIFDSDLCPDGNVTFDALSKLKHLERCILETLRLVPPVFIIMRKITAPLKLDENLEIPANTNVAVPVQGIHRNPEYYPDPDIFDPDRFLPENSQTRNQYSFMAFAGGPRKCIGYKFSLMELSVLTAMILRKFEISTIDKWETITLLPDVTLIPNKPLNFQFRRRATNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH77</accession>
    <name>A0A1D2NH77_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000043">
        <property type="protein sequence ID" value="ODN04445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH77"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="16553" checksum="B516F78A80DF7BBD" modified="2016-11-30" version="1" fragment="single">IPALFDMNKGFHVFVKHGDSGLMNAAGTYVCKDDHERSSPYYTITIPKELYSRITPDVTYLKIVQGQTQVFKCESKNGNVTLTFSGDRQPRPPRKVNTEQNDTSEYPFVAMYEVNPMEMTAEHTIINCVSTKDGKIIHSWEYSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIA1</accession>
    <name>A0A1D2NIA1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleoprotein TPR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01643</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN05008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIA1"/>
    <dbReference type="OMA" id="NDDLREC"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070530">
        <property type="term" value="F:K63-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043122">
        <property type="term" value="P:regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.990">
        <property type="entry name" value="Nemo cc2-lz domain - 1d5 darpin complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032419">
        <property type="entry name" value="CC2-LZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051301">
        <property type="entry name" value="Optineurin/NFkB_EssMod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31553">
        <property type="entry name" value="NF-KAPPA-B ESSENTIAL MODULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31553:SF1">
        <property type="entry name" value="NF-KAPPA-B ESSENTIAL MODULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16516">
        <property type="entry name" value="CC2-LZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NF-kappa-B essential modulator NEMO CC2-LZ" evidence="4">
        <location>
            <begin position="353"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="455"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="157"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="580" mass="64242" checksum="0EC03C289932851A" modified="2016-11-30" version="1">MFSTPTASGVNSDTGASAMRVNIPGRPDDYYGGDFVEDGSFLVLSTDALSLSPTTPPGGDGDMSDEDTKNMDIEVLNSVDEDETNSSSTCHSNTQAQVLGEDPESSVDSISKMEEQKSESLNVGIRDPATSSVTNISLASASSSSTDAHLIESNEEVNLLMAENKKLAELLADSNEKMKQCITTTEKLKTDHEEYKKKHEASRDVISQLRQDNEVLKSQMSATQTTNDNAGSFQTELQRQSNEILELTEQLKTVLSVNGKLNDDLRECHASNEEFRAELDRLRAEKNESESKFDVLKAEIDTGRQTIAKFHEHRMRNEAELAKMRSELIAAVEKLQRMEAVVEEKTKLTGSLRRNMEDTVTALERCNLKLNQKEEEVSLLTTKIAAINAESDNSERLEVLQMQCQTYLADFEKEREEREKLAVEKEELLKQLNLTNQELKQRSDALDAYRHQYGNTEQQQQHHHQQAESASRNDNAAADNSNESLSSPLTSLPSVAGQFASFVRRELLVGKEDLGASLDTNQHTEGGAAETVVQQPTGIPPCPICRKTFSSLETLQTHASNCGDLDPFGGHPEDNSFVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIA2</accession>
    <name>A0A1D2NIA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lysosome membrane protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01879</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIA2"/>
    <dbReference type="STRING" id="48709.A0A1D2NIA2"/>
    <dbReference type="OMA" id="MANMTID"/>
    <dbReference type="OrthoDB" id="195015at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005429">
        <property type="entry name" value="LimpII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF51">
        <property type="entry name" value="LYSOSOME MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01611">
        <property type="entry name" value="LIMPII"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="478" mass="54302" checksum="257300A2A63809DD" modified="2016-11-30" version="1">MQAAKVVLGIGIAITVLAVGIGWVIFPQLLQRKITSQIRLEEGGELFERWVDIPVPIYMKVYFFNVTNPAQVRQGEKPILAELGPYVYQQKRQRVVESISVENDTILFRPKITYYFRPDMSEERLETDVITLIDIPYVGVVRKAMTLSPFARSLIRDISVDHNKELFMHRTVAELTFTGYKEPLMKDLADLQGEELLPNNTFGIYYGKNGTAGDLMQIYSGVGDNTLFGETISWKGNDMLSFWETDYCNMINGSDGSVFPPFVTRDRVLRIFSPDMCRSIYMKYHEDVEVLGVPGYRFITPREVLEDPKVYPENTCYCTEPGDDLEGCAKAGVFYLAPCRKGAPVVVSWPHFYDGDEIYVQQSVGLEPNKDKHETFIVLEPNTGSLIKASKRFQINVELKPTKHFAPMKKVQTMLMPILWADESVQLNEDNAEMINNKLMKPIQIVTIGAWSTLVVGLVLILIGSLLFARKDKKDFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIR5</accession>
    <name>A0A1D2NIR5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Alkaline phosphatase</fullName>
            <ecNumber evidence="2 10">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_01518</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="2 10"/>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIR5"/>
    <dbReference type="STRING" id="48709.A0A1D2NIR5"/>
    <dbReference type="OMA" id="NWENDHE"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF91">
        <property type="entry name" value="ALKALINE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 8 10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="7">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="514"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="556"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="599"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN05160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="647" mass="70995" checksum="667E123E8F996E92" modified="2016-11-30" version="1">MIIRKPPTSKVKVKNTVHFLCGLRCWGLQILVGCVLLSGITWAVPLSPGPDFDLTQAARPNPPLSKILTSENAPVPSASDGIVEIVPVVSPSIVSAPPENVSPSPAPLVNKRSAVFPQTLMRNMSLTEAETLSSTNSNLSTGIIHGAEKIGQVLLDSNLLINDDSICRSEECFETGTQMPSMRRQIAEAILMSDIRNKNRAAQYWRDEALDALHTKLLQRPIEAVAKNIILFLGDGMSTATITAARILKGQKVDNLPFGEEGELHMDTFPYSGMSKTFCSDAQVADSACSATAYLCGVKANSGTIGLTPDATKNNCTAQNNPAYQLSSILAWAQAAGKSTGIISTARITHASPAGTYARISNRNWENDHEIKQDRNNPDECDDIAEQLVFGDPGRNINVILGGGRLQFLPRAKRDPENGRKGYRTDGKNLIEMWKQEKFETRHAYVEGREQLLNVDTSNVDYLLGLFAPSHMEYYHEQEKHDDPSLPEMTAIALEILSRNQNGFFLFVEGARIDHAHHLDAGLRALWETVELDRAVKKADAMTNDLDTLILVTADHSHVMTIAAFKGFVNNKRYNISKDPVDDLKYRQVPNIPRKSETHGGDDVLMSAKGPFAHLFTGTQQQSFIPHALAYAACIGSGPKFCDNVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ11</accession>
    <name>A0A1D2NJ11_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fidgetin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ11"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ11"/>
    <dbReference type="OMA" id="DAYMRKY"/>
    <dbReference type="OrthoDB" id="10251136at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000022">
        <property type="entry name" value="Fidgetin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="4">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="AAA ATPase AAA+ lid" evidence="6">
        <location>
            <begin position="112"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Spastin/Vps4 C-terminal" evidence="5">
        <location>
            <begin position="156"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="23795" checksum="8706CB4233EADE35" modified="2016-11-30" version="1">MVRALFQVARLKQPAVIFIDEIDSILTQRSDTEHESSRRLKTEFLIQFDGCATQTEDRILVIGVTNRPQELDEAARRRLVKRIYIPLPDLEGRKQLVKNLLREYSSKLTENDFDSIAKMTDGYSGADMNSLCKEAAYGPIRDVGHMLQTLDAKNVRPMQMKDFVVAHRQVRSSVGKSDVDLYEEWDAKFGCHITSQPMDDDDELETSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK20</accession>
    <name>A0A1D2NK20_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative trafficking protein particle complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Perinuclear region</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAPP small subunits family. Sedlin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK20"/>
    <dbReference type="STRING" id="48709.A0A1D2NK20"/>
    <dbReference type="OrthoDB" id="10252102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14825">
        <property type="entry name" value="TRAPPC2_sedlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.70:FF:000001">
        <property type="entry name" value="Trafficking protein particle complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002395">
        <property type="entry name" value="Kininogen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00334">
        <property type="entry name" value="KININOGEN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905673" evidence="7">
        <location>
            <begin position="22"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="346" mass="39546" checksum="4B5DF149E7E1C159" modified="2016-11-30" version="1">MAKLRVSVILLAFLVSNLTAGDDDPFPKEEKKESKIELPTTDVEDSPAEDSLVEHSPVSPDLASLAHLADTTGGRAEPLYKLYGGEGESEGEGVTHHGWGDHHGWKGEVDIKHHGWKHEGGEGGEGEHGWKHEADQEHMGWHHDKHHHGHKHGHKHGHKHGHKHGHKHGHHHKHGHKHGHKHDHDHKHGHKHGHHHGHKHGHKHEHKHGHKHGHKHGHHDNPLFEMEFSPAGKEVQKEDHSYLNQFIAHAALDLIDEHAWRTSNMHLKIVDKFNDWFVSGFITASRIRFVLLHDLKNDDGIKNFFSEMYEMYIKYCINPFYSQNTPIVSPAFEKKAAFYGRKFLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK32</accession>
    <name>A0A1D2NK32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heat shock 70 kDa protein 4L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01054</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000019">
        <property type="protein sequence ID" value="ODN05638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK32"/>
    <dbReference type="STRING" id="48709.A0A1D2NK32"/>
    <dbReference type="OMA" id="WEQSPEI"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10228">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000004">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000767">
        <property type="entry name" value="Heat shock protein 70 (HSP70)-4, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="480"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="755"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="506"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="791"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="813" mass="91718" checksum="EF3639AB7B799816" modified="2016-11-30" version="1">MNWKKCNLSKMSVIGIDFGNEACFVAVARAGGIETIDNDYSLRATPSFVAFGERQRVLGVAAKNQAVTNLKNTIFGFKRFLGRRYDDPRVQEDVNKVPFKIMKQDNGGVGIKATYLGQEQVYTPEQLKETAENGIQAKVHDCVISVPSYFTDAERRALLDAAQIAGLHVLRLINETAAAALCYGIYKQDLPEPEDKPRNVVIVDCGHSAIQVCVCAFNKGKLKVLASTADPNLGGRNFDAALAGHFCVEFRSKYGIDPENNPRAYMRLLTEVEKLKKQMSANATKLPLGIECFMEEKDVTSSMCRADYEQICASLFQRVEVVLQKCLDDSKLGLNDIHSVEIVGGSTRIPAIKQMIEKIFRKAPSTTLNQDEAVSRGCALQCAILSPAFKVRDFQITDVQPYPIKLIWDDSLGEDGATEVFPQYHPVPFSRMLTFNRKFIVNFKNDDADPRKLKIKARVNMHGIFSICNATIYEKIENGENPEEPMETEPQVVPPAGDNPAPTNPPDSQEAGNGNTTASTEPMDNSENTDANATSADVNMEDADKKKSKKVQYKGKELPVESVTFGLSRPELDEKIMSETHMISRDRNEKDRIDSRNTLEEYVYDLREKLDMELNGFVEDSERQKLSETLTSLENWLYEDGSDEKKEIYVQKLEELKCRGDPIKERRIESEDRPRAFKEVEVTLQLARKQVDLYNSKDAKYDHIEQKEIDKVVKAIQESETWLEQTRQKFHQNYQPYMPVPVKCKEILEQRRVLESKINPILNTPKPKVEPPKEDPKASKKEDAKTKKNATEGSTTNNSEANHTPDPQAMEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK83</accession>
    <name>A0A1D2NK83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane channel-like protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK83"/>
    <dbReference type="STRING" id="48709.A0A1D2NK83"/>
    <dbReference type="OMA" id="YIAVFYL"/>
    <dbReference type="OrthoDB" id="1936208at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038900">
        <property type="entry name" value="TMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012496">
        <property type="entry name" value="TMC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23302:SF24">
        <property type="entry name" value="TMC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23302">
        <property type="entry name" value="TRANSMEMBRANE CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07810">
        <property type="entry name" value="TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="629"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="673"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="735"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="TMC" evidence="7">
        <location>
            <begin position="561"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="846" mass="96989" checksum="3705A953923E2ADC" modified="2016-11-30" version="1">MNREVTARKKDVWEEANAEFYTESYPSGSKTPTTHHRRPSRLAIPLPSHTARRGSLLQGSRHFGKSGHRRKPSVTALTYTSTMAATENANGTTTNANDIQVAILPDLSEGTILNEKKTWEELHRIKSMPVPMTQKRQLKAQLTNLPKLRLKGWSHLKYLVKKSWKNVRSRVIRSYKHTVFLHDSLQAIELRSGTAIVNVFLFIKWTLFLNLAISIGLIIFIIGPYLTNYFISDQTPSPANATTCETVDAYGSANNSKPDSPEWQRLIECCEALYVEELQSPNATRGGLSTIFKNLGWGDIERWPISFSFYHETTLYDNNHTPYHFDAMYVITGCFIFLSCLLLMVHSIARGVKEVIQLNEGEFYKYSNLVFAGWEHYTNDEPGAEFKRRVLRKEMRIALQTEAKKINDLMITKRQKLKIYLVRLFVNFTVVVLVIISGVFIFYAVEGTLKQESKLDLADDPTGLWKLAIGFIPSFVISIFNISYPLILSKLGKLEQYSRQWETSLVLIRALAIRIYSIYAAAYGFARNSYCIPLKGFCTKCDPQHANGLIEIPSSGHRKLCWESIFGLQIYRLMIADLLIKIVITFVTDPLRKLLKHCCKNKVTEKIGHLSFNIVRHSLDVIYIQTLSMMSFFVAPFSPLFAVIYCFLVFYIKKFSVLYNCTSPPDTFRTSRTTITFMAAKMISFIIVLFTFVSYIGFMVPSRECGPFRGLDSPWQAMQMHLEVYPKLYDFLNRAGSPGVAVPISLILILLAYYYYSVAIANRAMVETLRHLLILEGHDKQYLFGKLNSLRRKAKPEVRRRSVFRSVRTKELKPHSRKSTAYKEYYKTIIDEDRNANANMQQGANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKA7</accession>
    <name>A0A1D2NKA7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Graves disease carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_01112</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKA7"/>
    <dbReference type="STRING" id="48709.A0A1D2NKA7"/>
    <dbReference type="OMA" id="YKMSVPK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002167">
        <property type="entry name" value="GDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00928">
        <property type="entry name" value="GRAVESDC"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="101"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="192"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="306"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN05545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="405" mass="44274" checksum="C7A642DE733AD15C" modified="2016-11-30" version="1">MCSGLSENKAKGLIGESDLFKKFTNFCATLKTEAIVFADGDEKQGTSSLNTASSSLKEKNRKEQSTTPSSSSIRVSPASEILEDVSVSPENLEMKEEKQFEFILKSLVAGGVAGMCAKTSVAPLDRMKILLQAHSKHYSHLGVFSGLRGIVKKERFIALYKGNGAQMVRIFPYAATQFTSFEMYKKLLGGEKSHIGRFAAGSAAGVTAVALTYPLDTIRARLAFQVTGEHVYNGIYSCAVHIFREEGGVRALYRGFVPTVCGMIPYAGLSFYCFESFKYLCMKYIPDYTCKSHSTNTGGLVLLLHAKLLCGGVAGAAAQTVAYPLDVTRRRMQLAMMDEKTKKFGMGMVSTLKLIYEENGVMRGLYRGMSINYLRAIPMVAVSFSTYELVKQTLNLDTGIAIKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL13</accession>
    <name>A0A1D2NL13_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium-coupled monocarboxylate transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_00787</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL13"/>
    <dbReference type="STRING" id="48709.A0A1D2NL13"/>
    <dbReference type="OMA" id="IMSTICI"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051163">
        <property type="entry name" value="Sodium:Solute_Symporter_SSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985:SF39">
        <property type="entry name" value="GH10366P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985">
        <property type="entry name" value="SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN05899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="22204" checksum="190E2F75DD0FE421" modified="2016-11-30" version="1">MSSNKTVFDVQDFAALFKWPEYCVFVAVLVVSMGIGVFYGFFNKKNRTHEEFLMASRSMSVFPVTLSLICSFVSAITILGTCVEVFYYGLIYIFFAVSFLPMTIAVTYLYLPVFFKLQLTSAYEYFELRFSRRVRLIISVSAIVHLGGLKAVLWSDALQAIIMIGSIIVVIAVGANEVGGFGVVFDRAREGGRLDVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLE6</accession>
    <name>A0A1D2NLE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_00619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLE6"/>
    <dbReference type="STRING" id="48709.A0A1D2NLE6"/>
    <dbReference type="OMA" id="IPYYLEM"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="8">
        <location>
            <begin position="7"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="126"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN06084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="37756" checksum="028A11D07DF6A70E" modified="2016-11-30" version="1">MSASLKEISKVLVANRGEIACRVFRTCKKLGIKTVGVFSEPDRNSQHVHLADEAYFIGPAQSTLSYLNQDKIFEVVKRSGAHAIHPGYGFLSENSDFARKCAQQNVIFVGPPPQAIFDMGIKNKSKELMIAAGVPVVPGYHGQEAASDLEALQQEALKLGFPLMIKAVKGGGGKGMRIARNADEFMSQAQSCQSEAEKAFGDGALLIERYIEAPRHVEVQVFGDSHGNCVYLWERDCSVQRRHQKVIEEAPAPGLSLETRAKIGTAAVNAAKAVKYSGAGTVEFIVENQDFYFMEMNTRLQVEHPVTEAITGLDLVQWQLLVAMGHELPIKDQSKVPGPFGHAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMN7</accession>
    <name>A0A1D2NMN7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tetraspanin-33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_00479</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell junction</location>
            <location evidence="2">Adherens junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMN7"/>
    <dbReference type="STRING" id="48709.A0A1D2NMN7"/>
    <dbReference type="OMA" id="IQTYRED"/>
    <dbReference type="OrthoDB" id="2014092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065003">
        <property type="term" value="P:protein-containing complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1450.10:FF:000007">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF489">
        <property type="entry name" value="TETRASPANIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0965">Cell junction</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN06206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="340" mass="38625" checksum="6D7A8E2779DD5F63" modified="2016-11-30" version="1">MRLFVYAEPKLQQDLIIKLSSSIDSSWNSDFKMRERPQQMERMIQLPHRYRRPRLNFISPFVKYTMFFFNFIFWLVGGALIGIGLYALVDQWQSGAGVRVEDLSDILFNVGLIIAIIGAIIFFVSFAGCIGALRENTALLKLYSVALLIFFLLELLVAVLCFVFPNKMEGIIASYLTDNVIKKYREDPDLQNLIDFIQIEFRCCGLSTRSYEDWSKNEYFNCTGPELNPSVERCGVPYSCCKNATDMSSGLINIMCGYGVQREMQIGTRDPISTTKSAASLHNDPKDKVWTQGCIEALKSWINRNLYIVAGSALGIALMQLFVMYLAKSLEGQIEMQQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN27</accession>
    <name>A0A1D2NN27_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Tyrosine-protein kinase-like otk</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_00030</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NN27"/>
    <dbReference type="STRING" id="48709.A0A1D2NN27"/>
    <dbReference type="OMA" id="HKILTSC"/>
    <dbReference type="OrthoDB" id="2413561at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000200">
        <property type="entry name" value="inactive tyrosine-protein kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF573">
        <property type="entry name" value="INACTIVE TYROSINE-PROTEIN KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000615">
        <property type="entry name" value="TyrPK_CSF1-R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="153"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="259"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="407"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="15">
        <location>
            <begin position="493"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="731"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="671"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="875"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="879"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="880"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN06678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1024" mass="114252" checksum="A2BD360D23EEAB03" modified="2016-11-30" version="1">MAMYVVKKYRKERPAMIKQKHSIPGSSKYFSVNNPKVAVGFHATDYDYGYSSVDPNLRLSLCHHKESLEKINGAINYKAIWRRCEEIHEIRGDEHTVFSNGSLSIYRVWSSDEGIYKCLVPSYEFSEEEAQIYSASLQIAYIEPLSITTSLDPAPLIPSHKLAVPEKGTVEIFCERPKGLPTPRVWWEGPDGRVILETSSSAQPSSSVSVFSSSRTREPNTLLVPNVRADQTGNYACVAENMEGTSRATVQLVVVTTPPTILGHPSSTVVKEGEEAYFICQFRGPSYPVSQIQWLRNKVPIPARTFLTQDDQADGPILYPVVSSSVDASGGNIIGSGGVGSSSGGGSDQQKPLARFISFPENGTLKIEPVELTDVGDYTCEIMTPGYMTVESRPAQLFVTETLKFMPKPVDRKLELGSTSKIHCKAHGASPLKIRWVKEGQSLFEWPAHIKEVNGTLHFHTVMDSDKGRYTCVATNAEGLINTTIYVDVGVTPKFSVVPKNPTEVLEGKSLLIDCKAYGIPMPTIQWDKNNIMNGFDRERFQVFENGSLLVTEVLKEDDGRYGCTAGNSGGFIREEVRLIVKSNDQYYSESLDDAVMTRTVSITLSVAAGYMLLVIGLMLWCRQRQLKRKQAYLTELEKENGDEEMKDSGPISNGSAPLLIPNGHQQLKADSCRESVKSDGETGKSTHSSIGGKIASATASIASHKSALSSHSKKSGASGYELLSYPRQDLQFVMLLGHGDFGEVFLAKAKNIVKEKSSTALDGDKEMLVMVKALQTREESALFEYKREIDMYYKLSHENVTKLVKLCRDMDPHYMLLEYSDWGDLKQFLLATRKDNPRKVPKPPPLTMAQILQVISQVALGMEHISNYRFVHKDLATRNCLISTGLKIQVSNPNLCRDTYASEYHKFRNQYIPVRWLPLEAVLEDDYSTKSDIWSFACLVWEVVHQAAIPLSHLSNEKVIESLEKKELLWDPTQIQKISVPQRLQNLLTQCWDANPKNRPSFSSIVITLSEISKESLLNSNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0X4</accession>
    <name>A0A1D2M0X4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division control protein 45</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_20070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008013">
        <property type="protein sequence ID" value="ODM86612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0X4"/>
    <dbReference type="STRING" id="48709.A0A1D2M0X4"/>
    <dbReference type="OMA" id="NEWAERR"/>
    <dbReference type="OrthoDB" id="10258882at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902977">
        <property type="term" value="P:mitotic DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003874">
        <property type="entry name" value="CDC45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507">
        <property type="entry name" value="CDC45-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507:SF0">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 45 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02724">
        <property type="entry name" value="CDC45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM86612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="284" mass="33297" checksum="48DB7A433C32152C" modified="2016-11-30" version="1">MLVDHYRRDLMDKLVGHRVIIITAQDVDSVCTVRILTSLFKTEGIQYILLSCSGITDMKAKYADYSSQSDKFLMINCGATFDLLETLENPPKEKTFFVLDYHRPIHVINYYNSTGQVHIISVPEPEEVIPEFDQIFREVPEDDDEEEEVDEENSEERRQRRADYNEWAERRQKILFDYREYSYYARPSALYALEVVWVMSRDDMESIWCTIVSLTDSLIMRRLPRAKYTEFASTVNDHILRISNAQTLPRDCLKVRFGRELFFICIATGPSTKARWEPPTSSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M107</accession>
    <name>A0A1D2M107_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock cognate 71 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_20081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008076">
        <property type="protein sequence ID" value="ODM86601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M107"/>
    <dbReference type="STRING" id="48709.A0A1D2M107"/>
    <dbReference type="OMA" id="FAYAYEN"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd24028">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM86601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="453" mass="49890" checksum="B04CE0D9B63D92CE" modified="2016-11-30" version="1" fragment="single">MNSQDQPAIGIDLGTTYCCTAIYAKGKVHVVRNGIGKNTTPSYVAFNIGKEIVGDAAKRQAFSNPENTIFDAKRIIGRKFGDPKLQEDMRLWPFSVVDEQGIPKIAVGDRNLHPEEISAKLLKQLKLDAEAYLGEKVTKAVITVPAYFTDGQRQATIDAGTMAGLNVLSIIAEPTAAALAYKLQHSFENRERNVLIFDLGGGTFDVVVMRTSKGKIDVLAVDGDTHLGGEDFDKKLMEHCAVEFKKQHNIDLFDGKDSKSKQEKDEARRKLKRLQGECEKRKVELAAARLAEVNVDNMHGDIDLSVMVTRNTFEELNATLFQKTIKIASAKLDKSRIDDVVLVGGSTRIPKIQELLQNYFGGKTLDCSINPDEAVAYGAAMHAAMLNGLVGKDSAEYEEIQDVAPMSIGLQMYGGGFSVIIPKSTKTPVKAKERYRRLMIIRLVPNYHLSGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1W9</accession>
    <name>A0A1D2M1W9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19714</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006594">
        <property type="protein sequence ID" value="ODM86968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1W9"/>
    <dbReference type="STRING" id="48709.A0A1D2M1W9"/>
    <dbReference type="OMA" id="MKGKAWC"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019427">
        <property type="entry name" value="7TM_GPCR_serpentine_rcpt_Srw"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF22">
        <property type="entry name" value="PROCTOLIN RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10324">
        <property type="entry name" value="7TM_GPCR_Srw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="236"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM86968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="388" mass="44406" checksum="A01B46851C70860C" modified="2016-11-30" version="1">MANFTVFNTIINILVTILFHASAETHYETHHKNQNDRHELYQRHRHFNGHFWPVLKELNLTGEKIGTVNAESWEASFKDSSRFWVHYSILPGVVLVGVLGNSVTIHILSRKPMRSSTNVGVKSLLYLTALAITDIVYLLFSFSMSWRHFPIVKNIWLYWLYSPFGLWVTDASSKKAKNAICCTEKRAFGVSIVVCIICFALTSTTPFEWRATAEVEEFEEYNETLYSLESTEFGSNNAYRLFYHWFTTITFVLLPLVILGILNFFLIRAVRSSSRERMLMLGENLASILKLLTSRVENRVTVTLISVVILFLICQMPTALVLVYTSIHVPERDSKENSVLLGLGNIFNLLVAFNAASNFLLYTALCDKYRKQFCTFFCLGKEFAAGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M215</accession>
    <name>A0A1D2M215_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc carboxypeptidase A 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_19674</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006470">
        <property type="protein sequence ID" value="ODM87009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M215"/>
    <dbReference type="STRING" id="48709.A0A1D2M215"/>
    <dbReference type="OMA" id="IHICTSA"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="11">
        <location>
            <begin position="38"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM87009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="273" mass="30939" checksum="E6C6EC82A6C80BF2" modified="2016-11-30" version="1">MLQNDIRTNVIVEDVKKLIDLEKVNQDKIVDGRLEWDRYYTLEDIHQSLDDLASINNATASTFSIGTSYEGREMKAIKISKSGETRPAIWIDANIHAREWITGAVCNYIIDQLLNSNETEIQSWLDEYDFYILPIANPDGYEFTHTTDRFWRKSRSENGSPVGCIGTDLNRNFDFHWLENGGASSNPCSNTFAGNSPFSDSEAANMRDFLTSISSRLVFYLSLHSSAQYILFPTGFDDTPIPQYNTYMSIGNLAAEAHGIRHELILLLAVFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2J6</accession>
    <name>A0A1D2M2J6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transport and Golgi organization 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006018">
        <property type="protein sequence ID" value="ODM87162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2J6"/>
    <dbReference type="OMA" id="NIEWTRR"/>
    <dbReference type="OrthoDB" id="191601at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="22423" checksum="51E5BB5748C77E98" modified="2016-11-30" version="1">MCILFLYVANNPSRDSYKVILAVNRDEVYKRPTQVANFWGTSPDVLGGRDMQSGREGGTWLAVSKSGRIGALLNVLQSAESLSNASQRRGRGFLVNDFLLNPSVDAVQYMSKIHSASEYNPFSLLTVDVLNRAAPQVCFYSCSGDNKPQELPSGTVYGIGNSFIDIPFQKVIHGKEAFTRVVNDNIEWTRRKVSLMAFWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2T7</accession>
    <name>A0A1D2M2T7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 4c3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_19395</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005668">
        <property type="protein sequence ID" value="ODM87287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2T7"/>
    <dbReference type="STRING" id="48709.A0A1D2M2T7"/>
    <dbReference type="OMA" id="PENCTGH"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM87287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="153" mass="17619" checksum="DBF8179D23D0FB75" modified="2016-11-30" version="1">MITQFRDRAGDDKNDDEDSFQNMLRFMVKSGLSEDGILAEVKTMLLAGYETTSSTIHYLFFMLALHQNHQNACREEILRVFDDPLRYEDLEVPSGSNVAVSIFQLHRSPEYFPNPDEFQPERFLPENCTGHHSFAYVPFSSGPRSCIGRSFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M327</accession>
    <name>A0A1D2M327_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbonic anhydrase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005470">
        <property type="protein sequence ID" value="ODM87370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M327"/>
    <dbReference type="STRING" id="48709.A0A1D2M327"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="287" mass="33006" checksum="AE0494536DE20764" modified="2016-11-30" version="1">MERGLDESSVKLTGGAVKGGHLTFQTTMLIRIARDWKSQGSEHRLDSKGEQMELQMIFTIAGSADPIKYWHVLARVQNRLFQFREKLVIILSVLVDALETEEDVIRKIEEEGTLQDPYLFEPFTQAVYHFRKEREDHPEQDEPRGSTLIAEVSWPPCFGYVIWSVYEQRLYISKRQFDEFIKIPAFGMVDHNRASENFRREDQITVEEENRPNIDYATLQNLINKRTVDRFILEGIHDHTPEGDDALVDEAVYYLDSEGISQKRGGGTCATTTTLALLSTIYGAARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4K1</accession>
    <name>A0A1D2M4K1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004445">
        <property type="protein sequence ID" value="ODM87896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4K1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="182" mass="20018" checksum="CA581214370A00A7" modified="2016-11-30" version="1">MDLLDNETVVDLQSDEGTSHDQPLIPSSRCSSNIKKLISAGIIILLCLSFITWLAVWESEKATIQPSPTTTVRPGPLPTIRPLPKNATDMAAKDLLLLVFDKHQLDYMEIKCHPQHPPTFKVMLLVENVAKFTGASYTMTHAIAAVSREAAESMFGLDYSHNIPLPPPSQACQPVMCTFLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4L3</accession>
    <name>A0A1D2M4L3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004418">
        <property type="protein sequence ID" value="ODM87913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4L3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="20597" checksum="2DDAE9246A103A8D" modified="2016-11-30" version="1">MFCNSMCGYPLQKGSRILAILDLLIGILVAAYMLYTLIIGYLGDNESEFRTGHTTTNGTTTTENITGFLTMTKLDRIVIVIIYIIVEGWLFRLLIKASKHLNQKACISWMKVRGISLLLWCVYVLYGVITGRHETIEMTLESIIIIYRMYELVVVAELKNEIEKSEAARKKEALTHQDELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4U2</accession>
    <name>A0A1D2M4U2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004295">
        <property type="protein sequence ID" value="ODM87983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4U2"/>
    <dbReference type="OrthoDB" id="6328985at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="53"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="19602" checksum="E02D38E9590AE4AB" modified="2016-11-30" version="1" fragment="single">TGERRIVSCCPNLYSNVAMNTAIFILLAIASLLLVKAETGDSEIFNLINLGQVEGKNYFYEQGVAGRNWTTAGKYCQESGMQLATIETQAQADFLKSKYSSDGFTGNYWTAARDAHLPREFTWNTTGAMPSEISGLPWSAVNMRMEYRTCVFYSAYSSPSLYLFPCDVTLSGVLCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Z3</accession>
    <name>A0A1D2M4Z3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004179">
        <property type="protein sequence ID" value="ODM88057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Z3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="183" mass="20322" checksum="0B63B20485F1F397" modified="2016-11-30" version="1">MPTPRRIIELNLTKLPFLPFLVLTVSTHKFIIGLPDRWPIPNPRFRLVLFKTLLAAVIISGCHLDMTLDAFVNAELLSLDSSCQTTTFDYIIVGAGRLYFVHFHNAPKTTMGRNFNVELEWVVATRIANASSFASILLLEAGGEPSVLNDIPAFDATSRTNLQIPGFIIPPSKSTLAKIVMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5W9</accession>
    <name>A0A1D2M5W9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003688">
        <property type="protein sequence ID" value="ODM88368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5W9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="10553" checksum="6BD9352B7CAC4EE2" modified="2016-11-30" version="1">MSMVTRSRKKNVGEGCIHEVVLHQSIICHLRGDKFIVNGSEPLQSTYPGMLEKERILELIRQNDISIINSEMGSGKPLIFLSLYLSLGTVAVAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6G9</accession>
    <name>A0A1D2M6G9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003427">
        <property type="protein sequence ID" value="ODM88556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6G9"/>
    <dbReference type="STRING" id="48709.A0A1D2M6G9"/>
    <dbReference type="OrthoDB" id="16911at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="368"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="585" mass="67442" checksum="CC5EB6B8B5B839E2" modified="2016-11-30" version="1">MLRGRDPHQKYPLLPPPLKRFDEEDDVDHSDNFESESPQSEDSLPPAPWNELPNECRGVHPRWKSGMDSLLEQACLEGWTKWKPWCSSSPFLNSGVTYGFPILKAAASSKGFNLNSSLFPSSILDKTHQGNPFPTKSTFLKFITSHRFHYERNVLMKVEEFFSNWGNHLTSLTLWSFTTQAKIRPKGLQIILQNTPNLKALTLNGMSIDLTRSKSLFENEEARLPPLSKLEHVLITDVYSEGNDPVAEEHNLCNWVLDPYKQQLVGLETDSHFGGGGHESPLNYANLKQLKMWMPKAVVMKAPLSCPQLERLSLRELSLLLVFRRGQYPLEMASSAREQLFRKRTPSKYEEKGKDFRTYLNEMLRDKDYRFFYEYQMRAVMSTERFLLIDEAETQSVKRVESEAVLIVAPTGSGKSGMIMLLPRRRVFFQVTGFCKKENSDECDDEGLENLLETGMIITDANQIHSRLPNLVIVNAQKFGGKSRLSLEYDNREIVDDVGSFFSQFDTLIVDEAHHYPAKTWLKIVQEFKKPAPGMQKQIIFITATPYRSIRKTIRRQEFTDSGKRSELVWISSDFWNRIESWSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6Y8</accession>
    <name>A0A1D2M6Y8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="5">PARP</shortName>
            <ecNumber evidence="5">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_17991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H(+).</text>
            <dbReference type="EC" id="2.4.2.30"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01003311">
        <property type="protein sequence ID" value="ODM88691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6Y8"/>
    <dbReference type="STRING" id="48709.A0A1D2M6Y8"/>
    <dbReference type="OrthoDB" id="429950at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990404">
        <property type="term" value="F:NAD+-protein mono-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070212">
        <property type="term" value="P:protein poly-ADP-ribosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF60">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PARP catalytic" evidence="6">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13345" checksum="D36F689112CC29D7" modified="2016-11-30" version="1">MQKPLRQLMLLCSVSLGRVYESPHGFQHWSAKGGVPHGFSTIKGMGKFVPYWGENFGDDSVIVPCGKTIQNQKFQTYNLDFNEYIVFEGKRIKIKYAVDVEIKPASSRHQDVSETYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M848</accession>
    <name>A0A1D2M848_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Metalloendopeptidase</fullName>
            <ecNumber evidence="3">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_17526</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01002853">
        <property type="protein sequence ID" value="ODM89156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M848"/>
    <dbReference type="STRING" id="48709.A0A1D2M848"/>
    <dbReference type="OrthoDB" id="3256376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF886">
        <property type="entry name" value="ASTACIN-LIKE METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 3" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="7">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="454"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="530"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="554"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="563" mass="63510" checksum="62EA6AE2D93A5BC6" modified="2016-11-30" version="1">MTRQVILIVERGFEEFQSKTCIRFARSEAGNQDFVSIEVDNTICAQAHVCKRGGTQFIRVGKRCMNMTTIIHALGHTLCLGHENQRSDRDKYLTFRNCNPIPRKRIRNIYIKKGIYDYASQMSHECNWCAGGWPTMPNVTKCGPVATPGLSVLDADRINDRCYRHRWRPIESLSFKDKTNLYGFGYEKLYVCRAMIEGGIVAGKFDLDSKICLIYYNFKMHVVKDIFEVLTIPGGLNRHCSVYSLVHRNKSILANALPVGTQVDSNGYWNSYIALGEVPTGNCSSECGVGNTWVYNRSGFWNDANLVVRDVGALSSNYKVSTCEWDVKSPSFIKTKLVEGPNIFQPQGNANNFSQTHENTQQSLPTLYISVGTVLLCLLLLLICISSFFFMRYKKMKRFLTETEYKEFFDGRLRLTNLAEDRNGIENEGVLVRDDIDALKFYEHFKLLRNQITIDVEQLLGSGAFGVVYAGTAKGIKAAIKVPKPGCSLETFKSFLSEVKVMGYLGSHENILGFIGAYVNEIQYGTIQDRGREPPSVAVPPGAESLRNTDNTKRRTARKTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAB6</accession>
    <name>A0A1D2MAB6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-terminal acetyltransferase B complex subunit MDM20 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16856</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002337">
        <property type="protein sequence ID" value="ODM89824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAB6"/>
    <dbReference type="STRING" id="48709.A0A1D2MAB6"/>
    <dbReference type="OrthoDB" id="1874341at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="844"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="844"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="972" mass="109396" checksum="E597DD02937379BA" modified="2016-11-30" version="1" fragment="single">VVMNGDLNAEAARLRERKLRFLYELVDSENNKKVITEVDRLLKKQPGFTCAKILKALALIRMQKTVEAKEILDLVIKEVPVDDGSIQALSICYKELDDHVTMSKVFEAASKKLPSEELMTHSFMAQVRTNEFQKMQLTALNLYKMYSKPTYFGWAVASLLIKADKLTPADSGRPISLTLAERMLGKFISEVDKTQVGGVEESILLLYLETLSKQKKWEEVLTALKDFIGYPDPSRARPGTMTPFMITEEYHLIQRIITLFKNDEEIGPEVKSLLDELLTKFQARVRADLQMACKFGAEKPSFYTDMIPYVNSPLLSSEMKEEFMQIVALHSKHDGDQDQDQSIYSSVRDIIRDVNYELLDRDLFPDPGPLQRKSRAERCLLKYFSADSISSSLRSGSESDKNLITKEADYHDQFLVIAASTLMAKYDDDENDFDGVLSSIRSSKPEEIPLENLNLDENPQKSSYSLSDQDYLLMTAILLMEFGLKQCPYNHSLRILLIKAYTRIGAVQRACVVSTGLDIKHVQWDSLGFLIIWKVLRGGLYAISRQMLTVAESVYLNYKRDCMEHLITAYKFGSFGKIQEFEGFREQLLNSCQFGLIQVEKQLLQLSSTTLSSATNHPQVKISPALVAKSLEVEKTGGEDMFWKKKEFTDNRDFTILSYLESNQKPFENLKAKTGETDVELVKIRRALLVLLAETVVLVEEEKNSNPGRLERIDEALSIIREKTGLKMDGNCENVPYFNGLWPPAQLQYFEMGCLSTIVEMVGEVRKAIGESGAGASCLVSMSSMITSFWSGVKTRLTEKMSKLTILTMGGCIEDIHHVVETFSFACILFGVAIKAGKTREASGSGTAVSATSSRRKKKAASDAASKAAAQGPPPDFAPLKEVHSSLRDLIMEFRLVDICSIPPRANWHWSTAQKEWEGLLSDKLKEKVFAPAWDEVQQGIVDSYGLQLDQFMRAVDNNSKFVTGMETSSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAL9</accession>
    <name>A0A1D2MAL9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dopamine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002264">
        <property type="protein sequence ID" value="ODM89979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAL9"/>
    <dbReference type="OMA" id="CFIEDEP"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20905:SF1">
        <property type="entry name" value="AT07410P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20905">
        <property type="entry name" value="N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="230" mass="27026" checksum="6114994B585A3315" modified="2016-11-30" version="1">MAQLDHNELGEPANGFRFKFLEPPEYDEVLKLLEKYLYPSLSHVGYDPQFPDDWNQLFLRMMKRGKNLSYIAVDTETGEVAAVRMVDLVEKGVVSDLNGLSLFKDKKNMDIFELCGDICKGWDIFETFNIAEYADMFGLTVDEKYRRRGLATEMYRRGLNYLQRRGIKIVKCSFISPFTRRAGHKHGYKEHQRRYFHDCKNKEGEILNPSSDPTDFIDFGYFDLRNREIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAX6</accession>
    <name>A0A1D2MAX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BTB/POZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002227">
        <property type="protein sequence ID" value="ODM90024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAX6"/>
    <dbReference type="STRING" id="48709.A0A1D2MAX6"/>
    <dbReference type="OrthoDB" id="624345at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="130"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="299" mass="33513" checksum="0989240DFF408AAC" modified="2016-11-30" version="1">MQFVIVQNPEPGVVVPVHQAVNGERSWNIVLEAKLLPTITTWEPNQLKQLAIRFHGRLLEEMSGLCGEDVQFTFEGTLTRHGEGVTITIPFTTEALPSVHIPLLISRRSVADRKCKLNVLKSVMRTDVSSDISILGDGGFKISAHSFFLIAQSSVLKELLQQCMFGRLKLKDVSEKCIRALLEYLYTFQISLAVKSSKVTVELFIAANKYEIQPLQDKLAKMILERRNAWFDITATLDLFLFIRKLGRTNILDEVKGKIGQVLKSKGKVLIMESEGYQKLVVDDVNAAMEMCTAMANAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAY9</accession>
    <name>A0A1D2MAY9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002145">
        <property type="protein sequence ID" value="ODM90143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAY9"/>
    <dbReference type="STRING" id="48709.A0A1D2MAY9"/>
    <dbReference type="OMA" id="XTHRITI"/>
    <dbReference type="OrthoDB" id="410920at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024104">
        <property type="entry name" value="Tribbles/Ser_Thr_kinase_40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22961">
        <property type="entry name" value="SER/THR PROTEIN KINASE-TRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22961:SF16">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="28862" checksum="188F7427E20666BF" modified="2016-11-30" version="1">MKTPSTKKIIIEKEPIAFSSSSWEKSQHSTKRAGEYLLGPKQGSSPVKCIQQYLARKDGTDEFYIIKMLTMKGASEKETMDDIQGKTLLHTEHSLSSLLKYEDGVVHEHGMFRSTIDETHCNDKGEIVTKEVTKLCLVLDCYMPHDFSPKYSHITNMQYYLICLGKHLTSDNDLLKDQRGSPAYISPDVIIGKPYLGKPSDMWALGVVLYTMVYGQFPFYDQSPTGLFRKIKTGEFQIPVYHTHILTFPKTGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBD3</accession>
    <name>A0A1D2MBD3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KaiC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002047">
        <property type="protein sequence ID" value="ODM90305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBD3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9766" checksum="4C7E0EF19740FD13" modified="2016-11-30" version="1">MASSSRRSSTSTTTASISAFDNRRAYKRQGLHPGTVLEIKGPEKSGKTFLLTYFIARIMTVYPEKKVVLIETRQVLSQQLHLHSLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBR4</accession>
    <name>A0A1D2MBR4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein bric-a-brac 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16272</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably acts as a transcriptional regulator. Required for the specification of the tarsal segment. Also involved in antenna development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001982">
        <property type="protein sequence ID" value="ODM90410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBR4"/>
    <dbReference type="STRING" id="48709.A0A1D2MBR4"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003680">
        <property type="term" value="F:minor groove of adenine-thymine-rich DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046660">
        <property type="term" value="P:female sex differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000120">
        <property type="entry name" value="Bric a brac 2, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF109">
        <property type="entry name" value="FI07618P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="9">
        <location>
            <begin position="34"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="277"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM90410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="433" mass="45220" checksum="771DF4A106EC09EC" modified="2016-11-30" version="1">MTQTPPQQYCLRWNNYQNNLTNVFDQLLQSEAFVDVTLACDGHSLKAHKMVLSACSPFFQTLFFDNPCSHPIVILKDINWDELKAVVEFMYRGEINVSQEQLAPLLKVAEMLKIRGLADVSRGSGGTNGSSRDGHGSANDNGSSGSSGLHRNGPNPADFMSTSNHDSEPSSPIHSNGSNNLLSHPLLQGHPLNPLNSLLNPSGSSPSSAAHAHALASLNRRKRRKMSTPERTPSPPEDDLDDHSSNQLEIDSQNGDWNNDHSPRSLTADRASSSGEPSSSNLAGSGPSGAGLSMSLSNTPTPANTPSLSAAAAAAATVGMSLAGGGSLGSTTASSLVGPMGPAFLNLHAAAAAAAAVANANSSGGAGSVVGGSSGGNNPPSTSSSLASDLDLKPGIVEMIREEERVRNICIYIPFFLLLPNFLYFSTSFLNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBT2</accession>
    <name>A0A1D2MBT2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="36">Activated CDC42 kinase 1</fullName>
            <ecNumber evidence="10">2.7.10.2</ecNumber>
            <ecNumber evidence="11">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="37">Tyrosine kinase non-receptor protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="44" type="ORF">Ocin01_16311</name>
    </gene>
    <organism evidence="44 45">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="44 45" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="44">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="34">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="33">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell junction</location>
            <location evidence="8">Adherens junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasmic vesicle</location>
            <location evidence="3">Clathrin-coated vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <location evidence="9">Clathrin-coated pit</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="35">Belongs to the protein kinase superfamily. Tyr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="44">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="10"/>
    <dbReference type="EC" id="2.7.11.1" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01002005">
        <property type="protein sequence ID" value="ODM90371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBT2"/>
    <dbReference type="STRING" id="48709.A0A1D2MBT2"/>
    <dbReference type="OMA" id="ERQKVPF"/>
    <dbReference type="OrthoDB" id="635774at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002009">
        <property type="term" value="P:morphogenesis of an epithelium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09539">
        <property type="entry name" value="SAM_TNK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.680.10:FF:000001">
        <property type="entry name" value="activated CDC42 kinase 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000080">
        <property type="entry name" value="Putative activated CDC42 kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000107">
        <property type="entry name" value="Putative activated CDC42 kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.680.10">
        <property type="entry name" value="Cdc42-like binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055175">
        <property type="entry name" value="ACK/TNK-like_SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015116">
        <property type="entry name" value="Cdc42-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037085">
        <property type="entry name" value="Cdc42-bd-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050198">
        <property type="entry name" value="Non-receptor_tyrosine_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049587">
        <property type="entry name" value="TNK-like_SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24418">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09027">
        <property type="entry name" value="GTPase_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22931">
        <property type="entry name" value="SAM_TNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="24 39" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="27" id="KW-0965">Cell junction</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="30" id="KW-0168">Coated pit</keyword>
    <keyword evidence="15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="32" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="18" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="22" id="KW-0967">Endosome</keyword>
    <keyword evidence="23 44" id="KW-0418">Kinase</keyword>
    <keyword evidence="25" id="KW-0460">Magnesium</keyword>
    <keyword evidence="28" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0488">Methylation</keyword>
    <keyword evidence="21 39" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="31" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="45" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="12 38" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="19" id="KW-0808">Transferase</keyword>
    <keyword evidence="29" id="KW-0829">Tyrosine-protein kinase</keyword>
    <keyword evidence="26" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Protein kinase" evidence="42">
        <location>
            <begin position="125"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="41">
        <location>
            <begin position="373"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="43">
        <location>
            <begin position="972"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="40">
        <location>
            <begin position="478"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="40">
        <location>
            <begin position="720"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="40">
        <location>
            <begin position="755"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="40">
        <location>
            <begin position="854"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="40">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="40">
        <location>
            <begin position="538"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="40">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="40">
        <location>
            <begin position="727"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="40">
        <location>
            <begin position="763"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="40">
        <location>
            <begin position="865"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="40">
        <location>
            <begin position="905"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="binding site" evidence="39">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00004600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00011903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="35">
        <source>
            <dbReference type="ARBA" id="ARBA00060742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="36">
        <source>
            <dbReference type="ARBA" id="ARBA00072244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="37">
        <source>
            <dbReference type="ARBA" id="ARBA00077194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="38">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="39">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="40">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="41">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="42">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="43">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="44">
        <source>
            <dbReference type="EMBL" id="ODM90371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="45">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1019" mass="113202" checksum="9189F94725D0E4B4" modified="2016-11-30" version="1">MVMSDDEGSEWLIQILKETQLEHFYVRIRDELQVTRMSHFDYVTLEDLENIGMGKPGARRLMETVKKRKTKLKSKNLVNKILPSSISQSKLPKSTSSSSGAVKKNTSTLDFNPGSITCLIQEKEIELGQKLGDGSFGVVLKGVWKTPVGPSVSVAVKVLKQDALHLPGVLQDFVKEVQSMHHLDHPNLIRLHGVVLSNPLMMVTECGHVSILDMWRWAIQVSAGMAYLESQRCIHRDLACRNVLLASLHEIKIGDFGLMRALPQEHDCYVMTERQKVPFPWCAPESLKARQFSHASDTWMFGVTLWEIFTFGEEPWIDLNGAQILHKIDKEGERLHHPDACSSSLYQIMSQCWAKEPSDRPTFPALRAYLSENFPQAMEVNQSYHEEDAHKLTLDAGDKVAVIEGKPENYYWKGQNERNYEIGIFPRCLVSPLRKRQSDDISKPLRNSFIHTGHGSISEKSWGSPCFIDEVYLKNPMEPPDLSGIPEDSDENSVPHLRDRAKRNPLTSSIPPIRSIQKSQQQQQQYSYSKFKDEPFSESRSGTPVTKLPTSKNSMTKLKQSEDILIDLSDDSKNNSMTNEPTSSSSYYNVTQPLSGSSKANCSKRGSAPPRPPPVNLLVNIHTNGSETTQQMYSNIPFMNNTALTQVSIPTNSTPTPFMQLQGDAQSTSYGFAPSVADSAEWSQYSETDSVHNGCSSPDPFDTSNFVTTPPAASRYYSVVPQQSPSEESHSVEQQESKKVPENILREFDTLAVSNTGENTAHLQESQQLKSESSPQEKVIKPPIELLKKRDEAFSWLDDTLGGLKIGNTSKAAEESAHFRQSSTLNNLGSRSSVCLNTLDSGDEVWNNFSDVHSSHNGIQKPPSFIQNLPSSHSSNASGTRPYNLPPPPSFARCNSVSSVNSQNRPPPAYRPPPSPQNISQPSRTAYGYIPRCNSESNTSQNLSPVYVLSSAVPSASQDEIIYALRACQDVATAEKSLKVDQLLKLGLGTRTGCEQALSSVKWNIELAASALLEGTSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCC3</accession>
    <name>A0A1D2MCC3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ZNF277 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001893">
        <property type="protein sequence ID" value="ODM90589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCC3"/>
    <dbReference type="STRING" id="48709.A0A1D2MCC3"/>
    <dbReference type="OMA" id="YDRFYLI"/>
    <dbReference type="OrthoDB" id="278606at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040048">
        <property type="entry name" value="ZNF277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="44627" checksum="2C6C859F6D6B7BAE" modified="2016-11-30" version="1" fragment="single">IWTIGGKDSSLLRSPSFALDLPRKNLETHWKQNLKRLEILETPRRDIVLDVNRQEREGSTFCRRCLFCHEVVTGGNRSDYFLHMWNCHSFHIGQPDNLVFVKEFFQLIEDKLNRLECLFCENIYKDELVLKEHMRKKQHRKINPHNSEYDRFYVVNYLEPGKTWEDIEMEDNTEDENREEEWTEVSEENQRNVVCLFCSERDAVFENVLDHMKTEHHFDFCGLLNRLVFMKRYELSKFGLQFKEGMIMLLISLQVKLVNYIRRAVYQLSCLSCDERFQDQGLLLAHVSEHNINGSVELLPTVEKWNQAEYFFPTYENDDFLTFLEDDDKINQTDDGAGGFDVESNVIPEDLPPMAKTNRDFDLAGFAMRYHNESDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCN7</accession>
    <name>A0A1D2MCN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001810">
        <property type="protein sequence ID" value="ODM90745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCN7"/>
    <dbReference type="OMA" id="RVWLIAT"/>
    <dbReference type="OrthoDB" id="8296303at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="159" mass="17035" checksum="717DFC3CB4FE0C72" modified="2016-11-30" version="1">MSSLGICLCPCMSLQKGVTVLAVIDAVLSSIFLALYILGLVALLAISKEDLEVTTEEKNIGIATCAIAIVIAILQILLALRLYYGGKNRDTRNCRVWLIATVVVVTIMVISFILNVSAGKFEGSSGAASLLDLTYKIYEMLVVSSFVKQLGQDVPYGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCT7</accession>
    <name>A0A1D2MCT7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001794">
        <property type="protein sequence ID" value="ODM90790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCT7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903821" evidence="1">
        <location>
            <begin position="23"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17166" checksum="76E859D04B49B3E3" modified="2016-11-30" version="1">MLTRFCIIAALLSLLLLVSINAVPADNELFQDTVEIQEGVEINSVTPFKAIFFPKVDTSACRFCRPPVSFHIMLFVNKSNNTYKILEQLIGNHIGCNSVVDSSVALGNGHGAALTMAVAVAVVDVHIKLKFNIDMTYDWSTSGSPLYARTLTEKEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCW7</accession>
    <name>A0A1D2MCW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Host cell factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15921</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001804">
        <property type="protein sequence ID" value="ODM90762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MCW7"/>
    <dbReference type="OMA" id="PDYGQMK"/>
    <dbReference type="OrthoDB" id="10001928at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.80:FF:000015">
        <property type="entry name" value="host cell factor 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043536">
        <property type="entry name" value="HCF1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059124">
        <property type="entry name" value="Kelch_HCF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46003">
        <property type="entry name" value="HOST CELL FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46003:SF1">
        <property type="entry name" value="HOST CELL FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13854">
        <property type="entry name" value="Kelch_HCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="1576"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="1664"/>
            <end position="1764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1179"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1785"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1183"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1206"/>
            <end position="1229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1807" mass="189094" checksum="89254A2BF0C336F9" modified="2016-11-30" version="1">MNASGDVRVLSSIGVAGTPSIPSADLNSKTMIINPTTNNDTPNAFGDASNVKWTKVNDAVTSQSIQPRPRHGHRAVAYGNYMIVFGGGNEGIVEELHVFDTTTQEWCQPQMKGEVPPGCAAYGLVLDGCRMLLYGGMIEYGRYSSDLYELNIPKWEWKKLKPKGPRNGEPPCARLGHSFTIIRDQVFMFGGLANDSDDLKNNIPRYMNDVYTLQVKLNNDNGIWDIPVTFGTPPGPRESHSAVAYVSKDGRHNKLIIYGGMSGCRLGDLYLLDVDTLMWCKPEVGGSTPSPRSLHTATLVGDKMYVFGGWVPMLVEELKNSEKEWKCTNSLACLNVDSLTWENLHQDILDDKVPRARAGHSAVVINTRIYIWSGRDGYRKAWNNQVCCKDLWQLEVQKPGDPGKVQLLRAGTNWLEVGWNPVPGADSYILQCVAYDVPSEPIFQPEPTPVQPLQSLAAAGYAPTPPIMTPVPISKPAKSIVPPAKDVMSQAAPGMSPAQAVSSPMLATSVPVSLMSSGGVPMSVSLQAGSISQAANVLSQGAPVASQQLANDNAQSSVMTLSMPSLSTANVGADISNAMTVVSATSVSPAVLPSVSSLYTLPANVAGTASSLLASKGMARPIATPMTASQAAGRGVLRLRTPVQVTQPRTPGTMTTLANANVLKSSPNAGVLATSSADASSVQLSGMHTLAAAAAATQKIQTPPQAMKVVPQAPGQQQVYSQVKVANMSGVLPGTVRLSSSPVNSPVKQVTTSASTPTAGNVKQIIVQKPGAPGGGNQIYTVVKTSQGMALANLQGSKVIQGKPGVSTANVVPASSIQGSPQKTANIIKWVAAPGSGVATPSKPNIIATNQPMLGLAGQGTAGNAPRPTYIISKPATTIAGRPQTPQYVVVTQASAIRSIQGMTTSTLSGNQTITLPTSAAGGNPMKMIVMPSSSGAGTAGQSVKIITPGGMQTANAPKTVTLATSKPTQYLTSTGQIVTIPQGLLQAGGQQQISIGGKQVTLQMATGQKLAILSNSSGQLIQSTGQGGEAGKPKFVMVGAGQKTNIPTTMSQMRLSMGGVIQSDATSSSLADGIGAAAEGLVEMAAGAELQGVSTDQQNLNGMNPDGDQSGGLKGGSMYGPWSKFSFSGLPWMKLKGGMEPVDYAMSMRDHTLPIYSLSTKFSWKSALNMGLKGGDEVDGVINQQAPPTENPQQVNEAPSELLAQPVQQQSDNSSQPQQQMEQQAQSIQFSLGEAATSAFPSLEGTPDPTPPVLINPDMKPELMSLQQQIADNANQDTSGATLAFSAPVVTTAASLLPAGGISENVAPQEVAQPPPELNLLTQSQLKMEVSAPQGELQQSPVTLTFSQPSLGMVPATTSYELSTPQLSTPIQAPVTAESSLSVPTQMDTTPSVTASQVQQNLIQTGQAPGKSVTLVNAQQLLDRSLVVSSPSLVSVSNSLPASQTVVSLPSRVGQMGSIIMQPSIVSQASGATLSSIPVQVSIANPLMLPSGVSIPAQTAIAIQNSLSTAAGSGILSQAQSPIQTVVARMPMPAAPVVRQMPEVRFTSTLNNATPVLPAASTNGSAGNPMQLRMPPEEKIDNWMDVIHTKGTSCVVKCYFTTNEKLSRLEPDIPVDKDLEFIKKKVELKPATAYKFRVAAINSCGRGPWGEVTAFKTCLPGFPGAPSSIKISKSVDGATIAWEPPLNTPGDILEYSVYLAVKPPPNAPDPKPGTTNLSFVRVYCGPSNQCNVPTASLNQALVDTTSKPAIIFRIAAKNDKGYGPATQVRWLQESAAPNFAAPKTGILKRPAPMPPSVLTKRGRPDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDS2</accession>
    <name>A0A1D2MDS2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01001647">
        <property type="protein sequence ID" value="ODM91168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDS2"/>
    <dbReference type="STRING" id="48709.A0A1D2MDS2"/>
    <dbReference type="OMA" id="IPRIMAP"/>
    <dbReference type="OrthoDB" id="272985at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="314"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="405" mass="46612" checksum="73B9BFF98B94DDBD" modified="2016-11-30" version="1" fragment="single">MDLVQPDGVLPSPARRQLTPEQRHRQSELQRLRRAQLTEEQREEIRAKQRRRRAEATVEQRDRRNEYKRNRRAQSSAEKAKEIQNQHEMRRLGVRQTYKCAREPATTVQELYIGQMNFECECCGAFHFEDETRTDLKFSSCCEKGKVDLLPLAQYPDPLQSWLTVNDDNRAKSFEDLRTVNGVVCETFVEAAKLLNLLEDDDNWNKTMEEACQYQMPSQLRMLLATIFLIGEPTNPRALYYKFRDALMEDFIRNHDVEYAEQKSLRDIENHLLQFGKDCVHFGLPTPMAMEDNDNAEPIIQRNAIESERLIALMNTEQRDAFNMIMDSVEGRIDQKCFFLSGVGGSGKTFVYKALISANLARGDIVKVVAPTGLAATLLKNGQTVHSGFRLPINLNETSTSNIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME03</accession>
    <name>A0A1D2ME03_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pancreatic lipase-related protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_15473</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001627">
        <property type="protein sequence ID" value="ODM91205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME03"/>
    <dbReference type="STRING" id="48709.A0A1D2ME03"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903881" evidence="5">
        <location>
            <begin position="18"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="6">
        <location>
            <begin position="12"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="113" mass="12266" checksum="CB5E434DFD763CFE" modified="2016-11-30" version="1">MNVFVLDWVVYLVAKLCLEILFERSAYRAVLIGESLGAHVAANAAQAVEIVRPFTQNIKTLHKQDANFVDIYHTNRGLLGTTSDAGHVNVYVNGGTSQPGCLRADFTGLMGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG15</accession>
    <name>A0A1D2MG15_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">G2/M phase-specific E3 ubiquitin-protein ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_14772</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001380">
        <property type="protein sequence ID" value="ODM91913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG15"/>
    <dbReference type="STRING" id="48709.A0A1D2MG15"/>
    <dbReference type="OrthoDB" id="512616at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15669">
        <property type="entry name" value="ePHD_PHF7_G2E3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051188">
        <property type="entry name" value="PHD-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059102">
        <property type="entry name" value="PHD_PHF7/G2E3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042013">
        <property type="entry name" value="PHF7/G2E3_ePHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12420:SF42">
        <property type="entry name" value="G2_M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12420">
        <property type="entry name" value="PHD FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26054">
        <property type="entry name" value="PHD_G2E3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="58"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="187"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM91913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="559" mass="62223" checksum="39D01DB4CF2C5DAB" modified="2016-11-30" version="1">MKNVRVCYPSGSISLNEPKPCDAEIIWLGSDSRAASQIHTFSNVESSTLTTIKVEDANHVCVLCRSPKVDELRLGPLYFGEDLTAHYFCLLFAAGLVQKGDDSEGILGFLPVDIKQEAKRAFRLKCVFCRSIGAASGCCEKKCKTSFHFRCGLDNGIAYHFMGNYECYCVNHAKFTPAKEPPPDQECPVCLCTISKGESSVSASCCKSAVFHKECIQQMAFSAGYFFKCPTCNAQPNFQEEMRKQGVFVPEQDASWELEPNAFQELLFTYSTCDAETCECPRGRNYGARKGGWVLAPVQRLWSSGTHRHCGNLKTMDGWTCASCLEVGARAEQNKSVVKTVPEAPPPPEVNQPSTSAAARLRNVLASAFQSESSSSSPEETHDTPDDLNLNLALIHISPECQDYFPFGRAEIKKMAQKGNILMDWKNRDLAVSLVDVFDLRMPPPPEPNPAPPRQRPFKPAGTCTSQGRRLKRFRIRTLWSRGVVKKYKSAARVQPRPEKPKRKVKVVRENQQECLTPPAAQVEGELLEPRVLRSVNIDLKVPLTMPLRNLSTVNFLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHQ3</accession>
    <name>A0A1D2MHQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tenascin-X</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001233">
        <property type="protein sequence ID" value="ODM92432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHQ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MHQ3"/>
    <dbReference type="OMA" id="CICQKNY"/>
    <dbReference type="OrthoDB" id="5912242at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006149">
        <property type="entry name" value="EB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069">
        <property type="entry name" value="ECDYSONE-INDUCIBLE GENE E1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069:SF8">
        <property type="entry name" value="FI17111P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01683">
        <property type="entry name" value="EB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904056" evidence="1">
        <location>
            <begin position="22"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="EB" evidence="2">
        <location>
            <begin position="317"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="EB" evidence="2">
        <location>
            <begin position="418"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="EB" evidence="2">
        <location>
            <begin position="559"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="690" mass="73749" checksum="2537DA4261DC8CC0" modified="2016-11-30" version="1">MKILSWKLFIFLSFFITFTYGYGNTLIGGSCNNPADCVGDPGVTSECREGRCICRPGYFASIGKDDCLLLATGLGESCKEAPQCQKGTPGELSDCIDNICSCINGTSVPNENQETCLEVINEVLGKECEVTLQCTAGLPGAFSECVEELSEPPSGKKKCNCIADAVHSENKCYLKAVAVGGECEIDVQCTEGLGSLSKCEGKENKFCVCPVATSVPSGKNDSCLAITNKIGDSCSENIQCTTGKPRNLSECSSEGVCSCTIDSVNGVNLHVCHKKAQFVGDSCKIPRQCSVSLGERSKCNGKGECSCKPGNVASSDNKRCVVNGIHIGQPCENTAKCVGEPGTSECASKSCECVPGYIPSVGLDDCLKKVNETGGECWETKQCQQGDLGEFSNCFPKSIGVSVCNCTENAITEPDQKQVCRKKAVHVGDPCEFESQCYSSLGNSQCLGDKCVCLDTSTPSTNNTACLLKSSLNKACEDNNQCNWNQESPNSASCQLKNASDTSVGRVCLCRKNEFIESIDHPGNCLKILNETRLSCEEKVQCSAGLGNSSDCVDNFCMCNQNHVYFDGACYYPVVLEGICNSREECIVGVNNYTFCDTGRRCRCLPGASRYEDKCFVPKYVGDACGSNKECTFSISGPVYCQPSTGRCTCQMGFSGAFENTMCSGAIRRVASPTGLLALIFIAWLMSKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHW3</accession>
    <name>A0A1D2MHW3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001199">
        <property type="protein sequence ID" value="ODM92566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHW3"/>
    <dbReference type="STRING" id="48709.A0A1D2MHW3"/>
    <dbReference type="OMA" id="ALWIRIW"/>
    <dbReference type="OrthoDB" id="6372019at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="384" mass="41059" checksum="5CCC77426D5523F1" modified="2016-11-30" version="1">MSDAKMETNSDTAAQDGVADAGAAQNSTKGRRGSGGRPKMSRIMKDVQEGEALLKEMGHTDEGPELEGRRRTRSSMRGAPPPSTPPPVKRERRSGSSANATPNSAEKKKPTPTPPAKGRGRGRPKKDDVTENNVNDEEEEAAANDKEASTESRDEKAQSPEKMEVDTKEEEKKKKSESTTKKEKTPEPSPSKKDEKSKDSTTPVKEKVEEKKEKKEVNNKEEEKKAKAPEEKESKPAPPKEATPSPAKSPVKEPVVAAKPTPTKESTPTPEKKEVTPAVVKTPEPKKEEKKEEPAKPKESVPTSPAKPAAPQPTPATPEKPPATEPVKVQTPNATQVSNNTNSSPSLSKETSNANGNSTSSPTAPVSSNQTTSPASTVPPAKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHX8</accession>
    <name>A0A1D2MHX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein hedgehog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001190">
        <property type="protein sequence ID" value="ODM92609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHX8"/>
    <dbReference type="STRING" id="48709.A0A1D2MHX8"/>
    <dbReference type="OrthoDB" id="6021162at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007267">
        <property type="term" value="P:cell-cell signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00081">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001657">
        <property type="entry name" value="Hedgehog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001767">
        <property type="entry name" value="Hedgehog_Hint"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050387">
        <property type="entry name" value="Hedgehog_Signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11889">
        <property type="entry name" value="HEDGEHOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11889:SF31">
        <property type="entry name" value="PROTEIN HEDGEHOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01079">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00632">
        <property type="entry name" value="SONICHHOG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00457">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MACPF" evidence="2">
        <location>
            <begin position="343"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="906" mass="100855" checksum="4858244EEA6F7991" modified="2016-11-30" version="1">MAAHLPKTLEEFPKAFGNASLIEVMKKIKSPAALTPTETNIWKYSGGALLLGRPLDTVMIFMGGSSGAGKSTTINTLFEDNELCSTSSSTSETKEPVRLRKTLKVTKESPPVVGNLTFVDVPGAFDTDGKNEVANFASIKKFRESSIELQSRKKLANLKIPNVTATVYPNIILFVLNAMDNRIVGPNSFFRKSLESFKLHDLFDKNHPNLIIVLSHARSLGGKAKFATLLQQKTNDIRKIIHEILGVSDVEVVPVENEGEDQELEKRGDFYVLPNGELSHYNLFQAMIKVFTRNEDLMGRLFAGWYFGSNCPEKKQKVEVETSQIELEPLDVALAGQALKDLQFAVSDESIVPQYNFSSLGCGFCPVSEEVKPVYLLSETGDASALQSKVIEIESSKFLIPNFINAYIKKTSRFQRISFYEKEEYQNHMKASYGIEAGFKLIVSASSEGRWISGAQGSYGSSLVKMVQEIQMATFKLDNPRGRVTHSKFIQELNSLPSTFTNDTAKDFRNFFSKWGTHIIYEEAVGGSIQLKCTLQSTSLTKEKLQEIEGQVSAIFKGFSGSGHVETDALSKGLKTVGVSNEQLEIDGGDPPAIITLESVNAAQLQEWAKSIPKKPVELRQSIKLYPYYNFLDNGEQCESLRQATAVYLEDTLNAKIQTAIDRNTASEKAVEDTVDEKPKGPPCFPKGTLVELWNGERKQIEQLSLGCFPLKTMGFGNSPLRGEMKLDKIAKTNFCTFLDAKSSKLVEYLVFHFSNGKKLIVTEAHMIFQYIPDRHQVKGKQAKNFKIGELSVFLNPTSGEMETPAIEEITKEMHVGAYSPLTMSGTFFADGFLVSSYANTNSFLQAQMALFPLKMWCSMNRKGVKKQMDVNNEQTSALTKEGIHPYAKFLMQFRKSFTSMAPSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI66</accession>
    <name>A0A1D2MI66_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001175">
        <property type="protein sequence ID" value="ODM92686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI66"/>
    <dbReference type="OMA" id="GYSKTRW"/>
    <dbReference type="OrthoDB" id="7971529at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37162:SF10">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37162">
        <property type="entry name" value="HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="1">
        <location>
            <begin position="328"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="47993" checksum="ECA1B920408FD3AA" modified="2016-11-30" version="1">MAAKSKRKCHFTEEMKKEHPFLEKKFKGDDDSGDLFCRMCSGTFSISNGGQYDINRHLKSDMHKKAMIAKASTKPVTAFFSKNQPESQDLELAAREGLFAFHSVLHNHSFRSMDCTSKIIKEIYDTKFTCSRTKCEAIAVKILSPYILGKIRKELDNSKNDPKNELYLSFLLHQAKMFNDTVKLLEKEHACASEIGTILKSIINNLELRRSEQFIGTNTSKLLHNLIEAGEIQENSFRKYTDSFFETAIEYLNNWTADFEAVQFLDWIQLRKQVKWGDLEKVVTDGKSYGLHIDESALFNEYSCLKAYLTNEKLQELQTIPKIDERWQAILSHFETETIQTPVLESIVEFSLCLPGTNASVERSFSILNNIWSSEKSQLSLETLKGLMNLKINANCSCKEFYADLRKRPEIEENTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI69</accession>
    <name>A0A1D2MI69_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Testis-expressed sequence 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14025</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001178">
        <property type="protein sequence ID" value="ODM92663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI69"/>
    <dbReference type="STRING" id="48709.A0A1D2MI69"/>
    <dbReference type="OMA" id="CIVMSES"/>
    <dbReference type="OrthoDB" id="26740at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="10">
        <location>
            <begin position="290"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM92663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="527" mass="61115" checksum="E25147BB70114EE2" modified="2016-11-30" version="1">MAFKDCHNLKYWTVLLVCAMMFNLPNYLVYTVWFFMGAMCVNILNRLFNRVSYNFPVFHTENNLIGVLNTKSVTDDLHNSFQKSEGWMLTYPLESQNYSPALHSLNNIQVVLVRINSQQLKVSYIHSKHKIPKKKVCDEKQINFNTKDDKMFTQHEQFDLRGAKIEIVPVGLCRKRMWRKKYPISISFASSYLNHFGSNNFDGSTMKGEPQNGRKLYLFARTDREKDDWYRRLIYASNFTVTAVPIQLQLNSNQDPKILEFVNFMRKQCPNLKYRSSNQSTPTQHSSTTMPSVLNVFMARFVYDYFKSPSWKNNVRSRVRKKLMSIRKPMVVESIKLIEMDLETSIPKLIGVSEPWIDSEGVWANVETEYIGNISISIEIKLTSAQSFKTKNPNLSPMFDSDAEDSGDESESELMEYADSFAKSSVGKWIVENIATTPIQFTMEIRHVSGVIAVNFPPVPSDRVWIGFRSPPVIEMEVKPKYGDWTLDYGFLIGFIKRKILLELQHAIVYPNMIDLILEMKEITKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJD3</accession>
    <name>A0A1D2MJD3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001074">
        <property type="protein sequence ID" value="ODM93110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJD3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="325" mass="37494" checksum="363A8FF1B54C6CB5" modified="2016-11-30" version="1">MSRILQSQSIIGQIISRSFSRSGFCSTKYSLSVAPGHFCECCGINGTRHVSVVNKFKYGFSTPSISVQSSKFHTSLSTYSEESQDEEKRGEVEKSPRNEERRESVIDRLRRLSETPADDYELSPVAQEKARQMAEIRAESIRKGEHWKLDQRNMRPGGFPQQNQRYNNNRNGGFRDEEDFYGGGGGGRQPGYNRDRGFNRYDRNDESYGGGGRQQGGYNRNRSFDRYNRDDEEFDTDDLRDEPVDRSSWRGRSLSPKQSQYGQRQSREEQFDDNEPQDYEQEMERLRARLQKTKEEKARLQSSKKEAAPSEDIDSQERSSGASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJY4</accession>
    <name>A0A1D2MJY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Low-density lipoprotein receptor-related protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001047">
        <property type="protein sequence ID" value="ODM93195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJY4"/>
    <dbReference type="STRING" id="48709.A0A1D2MJY4"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="9430" checksum="EFCC5B1DB0098E52" modified="2016-11-30" version="1">MTMMMALPEKKTYFACLVVFLRFVKILSLVLPSVLLGFLVQPTDGCALSEYYCDNTRCISLDKFCNGVNDCGDGSDEPRFCSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKD4</accession>
    <name>A0A1D2MKD4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Insulin receptor substrate 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001011">
        <property type="protein sequence ID" value="ODM93362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKD4"/>
    <dbReference type="STRING" id="48709.A0A1D2MKD4"/>
    <dbReference type="OMA" id="YMEMQSP"/>
    <dbReference type="OrthoDB" id="946068at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="628"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="787" mass="84415" checksum="AD79D0F6A76A31CE" modified="2016-11-30" version="1">MQNYSKEDLIPRDRESRRHRTYTWNNDQTLGSRTSSFHSSAPPQMTRINSMDGSIPGCRNRIDSVSSSVSSKGFGMSPPVPIMSQTPSFAFNSPLCSTGTDSASSSYSIDYDNNNHHIPQQREICMARKLATPKVKMKMNASDYVETSLASKDSNSTAQTPSSYMEMQSPMSPFDNYMPMSPGCGSSSANLKNSVSGKISVSHSRNSSLIEEHDGYVPMNPTAHTCESGGCSTAGSTTGLDDQYLDMDFGRKLNLSNDDMRHMSPASSESIQSGTPSSDFPLEKVSSYLTDDFDDTNSMRPMRAYSVGSRSDTSSAGKNRAGKNRLEAVQETFRIRAMSVGSKAKRPFTNQSSGLFASPSSILPGGKSPAPPLSSSWSGSTGRWPANKLPMTHGQMHSQTAYTQPMHNHTGSESNDSDLMELDFSHNKSKSRKRSLPGPNGNHTASSSAGSGTSSVTKISPVAKGVSSGGGRDTPSKSDLGESSKSTPTPATTSCMVNGVTTMPKYASSAPISIQKAKSNDVGYHDSIGSSILTKMTGMDLKQLKELDDDGAYLDMDFTNKPSEKANTQKAAVTNQYDISSMKNNFLNRPVVVRPNESPTACKISRFSVNANPTSSSVHDHLSSKAESSPLVRSLSSSSNISTLSNHSNSSSNSSMSVKTQQEVDALCRNEISPKTSPLLHNSDHAAALSRIEECPEKLESRSLSRTPLQSPPRSPHHITTMEDESKVTYAAIEHLPPVRRGYSLNHPQAGPSSGSSCGSSAVSAKTSGVTYAQIDFVKSPETITPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKY4</accession>
    <name>A0A1D2MKY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prohormone-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000934">
        <property type="protein sequence ID" value="ODM93680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKY4"/>
    <dbReference type="STRING" id="48709.A0A1D2MKY4"/>
    <dbReference type="OMA" id="LCRRDND"/>
    <dbReference type="OrthoDB" id="4321958at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904198" evidence="1">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="23933" checksum="287A274099690732" modified="2016-11-30" version="1">MKSVMCTLTLAVLLAGVCHGWGGLFNRFSPELLSNMGYGGFSSYKLQPLINKIEKGELEEVMNEGMNEGYGKEEVCYGKKCTANEHCCSGHACVDVDGVLGTCLPTFGAKQGEMCERDGDCESGLICSGSDIKTCIPVTEAKKQYGEDCIMSSDCDITKGLCCQVQRRHRQAPRKACSYFKDPLICVGPVAMDQIREHVEHTAGEKRITAKANAFNHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLA6</accession>
    <name>A0A1D2MLA6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcription factor ovo-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000918">
        <property type="protein sequence ID" value="ODM93773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLA6"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="153"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="25600" checksum="0949C1A2359442CB" modified="2016-11-30" version="1">MDSFQNGKETSSDEEQAKDPPPVAIASSSKSCPPLNKPSTSAAARRHAMSEEKKCPECRVVYDGQSFRPVVEVSCGHEKCCRCLCESESGCRQCPKKGKKSSSPVKALKRNIDGKVKKVKVRPVEHDCPYCPMSFEYPNDLELHRTIHAAHPYRCCICSTAFFTKELLENHIVRVHYEPAQYAREIASLAVMQFLEQHVGNLEDQGSSESETTANDEKEEVVDDDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLL8</accession>
    <name>A0A1D2MLL8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Neuropeptide FF receptor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_12881</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000910">
        <property type="protein sequence ID" value="ODM93802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLL8"/>
    <dbReference type="STRING" id="48709.A0A1D2MLL8"/>
    <dbReference type="OrthoDB" id="5975505at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004983">
        <property type="term" value="F:neuropeptide Y receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14993">
        <property type="entry name" value="7tmA_CCKR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000611">
        <property type="entry name" value="NPY_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF9">
        <property type="entry name" value="LEUCOKININ RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01012">
        <property type="entry name" value="NRPEPTIDEYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="108"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM93802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="441" mass="50970" checksum="3EC8DC00086EE5C0" modified="2016-11-30" version="1">MRGQIDGRDNTLEGKFIVFSSSWRTNNNPRQSDLIGMNLTSLYHTICKENCQIMEQTLASVLPNETLAVTSNISTEELDTPTPYRLPLWGVVVMIIGYLCVFVFGLVGNCSVLIVVSRLHRMRTVTNYFICNLALADLLVLLFCLLPNLISNIYIPWILGWFMCKTVPYIQGISVCASVYSLVAISMERCISIRCPFRYRITKGKAKKIMLAIWVWSCSVALPWVLYFDTYNADSEHPEMLFCVEKWPDSHKSWSNYYFLFGNCLICYVLPLGIIFICYLTIWFRAYSHTFVLPSYNPKIGEMIHQKAKTAVTKTLIVIVLIFALSWLPLYVITLRMKFGSETKSDLENDLISFIYPFAQWLGCSNSGINPVVYSFLNKKFRVGFYMICKCTWNQQQTQPELPQLHRRHPLVRQTVNIELLKERQIPKMRVRAPSMLYDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MME4</accession>
    <name>A0A1D2MME4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Roundabout 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000876">
        <property type="protein sequence ID" value="ODM93984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MME4"/>
    <dbReference type="STRING" id="48709.A0A1D2MME4"/>
    <dbReference type="OrthoDB" id="428111at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031430">
        <property type="term" value="C:M band"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050964">
        <property type="entry name" value="Striated_Muscle_Regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817:SF172">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="73"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="203"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="309"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="596"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM93984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="778" mass="86311" checksum="D127A7A7E035D046" modified="2016-11-30" version="1">MNSADGSKSMRVTISANGTLQISDLRATDTGQYTCVASSVSGETSATASLAVESPVNPNIAFHRTNPSLLPPPPSQPVVVNETQATSITLSWTWNPNKAVMPRSQPLLGFTIESYSPDLQSGWLTLGHRIYSGTRPGEVIVHTVDGLKPDTTYLFVVRAENPEGFSAPSFISDPIRTKHGTRRSSDVEEVDEEEARNQLSGSDIELISAEPASSTSIRISWKVSKASMRFIDGYYIRYRDISPDQPLKGFNVLTVVAQKNHFDAYAHVIPNLKKYTMYEIFVGPFYKNVEGQPSNSKMISTLEDKPSAPPKNLVFKMMNSTAGSVRWSPLESQQHNGILRGFRVEIRGNDSRLHAEMDFGPNITSIVLSNLTLGRSYFVRVCGYTSVGFGPYSQPLKIEMDPALLSPSGAEQNGVTAEDGNAAQILKEVWFIILMGCLLFILLLFLVIILYTRRKSHGKKDHISSVMVAPHTDSQFVSGKQSLWIDQRWRPTDASDKDSNRSEAKLLANHHLVNGELGETTDYAEVDPQNLTTFYNTSNKGLSLHPHPQTLLQLQQQQMQAQQQPDLTPYATTTLIQQRRPNYDPLPSNPISLTKNMLNDSRDRESDQFSSGRSKLSIGSNNFNKFKSAHASPSPSPSAPLKMMPMSSRMGCYPSPGPNRSHLVPLEHQAAMPSLHHPYHNAHHANENLYHIGEIFNPNKSASVTNGFEAVYQSGDPEDNDPNVYTRSPYSSDVNGFQKLGRFQRPTVSQSHLDNDYHDWQHDPSAIKLAKTLKESNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNH2</accession>
    <name>A0A1D2MNH2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Zinc carboxypeptidase A 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_12294</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the digestion of the blood meal.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000813">
        <property type="protein sequence ID" value="ODM94385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNH2"/>
    <dbReference type="STRING" id="48709.A0A1D2MNH2"/>
    <dbReference type="OMA" id="NWGFKWM"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000040">
        <property type="entry name" value="zinc carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.340">
        <property type="entry name" value="Metallocarboxypeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036990">
        <property type="entry name" value="M14A-like_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003146">
        <property type="entry name" value="M14A_act_pep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF153">
        <property type="entry name" value="ZINC CARBOXYPEPTIDASE A 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02244">
        <property type="entry name" value="Propep_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 15" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904318" evidence="15">
        <location>
            <begin position="20"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="16">
        <location>
            <begin position="117"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="14">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM94385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="46949" checksum="7B606361277DEA64" modified="2016-11-30" version="1">MKSWFALICLLGLSVSVLGEQIRYDNYKLLRFTPTNEDELKLLVQLQESNFGVIFWQEPSRVGRPVDVMFPPHLQGDTFEFLRKRLVSTVMSDNVQTLINNEARGLLQNGKALNWESYGTLDDINEYLASVAASNSFAEVVTIGKSFENRDLNVLKISKSSGSDRPAIWLDGGIHAREWISPAVVTYVINELLTSNDTEVTQIAEDFDLYVMPVMNPDGYVYTQTDRMWRKTRATTNSPLGCRGADANRNWDYRFDTGGSSPQPCSDTYHGGSGFSQPETKAASDFYNTIGNQTKMFLSVHSYSQYILLPYGYSAERYPDYQEWMRIGQAAARAIAQPFGTEFTVGNIVDLLYVSSGGSVDWIKGIHDTSVVLAFELRDTGRYGFVLPPDQIKPSGVEFLEGFKVLVRELRTRLDMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP08</accession>
    <name>A0A1D2MP08_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Otopetrin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_12013</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the otopetrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000772">
        <property type="protein sequence ID" value="ODM94668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP08"/>
    <dbReference type="OMA" id="TMWITET"/>
    <dbReference type="OrthoDB" id="6429739at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015252">
        <property type="term" value="F:proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004878">
        <property type="entry name" value="Otopetrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21522:SF58">
        <property type="entry name" value="AGAP000074-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21522">
        <property type="entry name" value="PROTON CHANNEL OTOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03189">
        <property type="entry name" value="Otopetrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM94668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="486" mass="55700" checksum="D6DAF587B46F5EB8" modified="2016-11-30" version="1">MPDTAFVQRFCFGHLIHSGLLLCRQIIFFTTDDEKVFNRCANVANLILDILFPIYSFLLLFVIFKYSNVIINRHQEISRFALMHCISSSLCFWFWSILRETADSLYHKMTEHSRRTELHNSSHPLAHHHIPESLDSITPLAYTNRMIEEESHQNAFAFLNATSAITSFYDPCVEFSTISELVLKMSPYLYPFSIEYSILVGKRVGHHGSRCSNLHHNSPAASFTNHLVIHADCHSANKGLFAGLLVLVGTVVSVIIFYIALDDSSSGFAAQWVNLMSQMGLLILMIITVLCAYRQITKLDVNMNPVSLLDDLLLFLCLPSFFLYTIFTVVPAIAHQDYYAIVVCTLQVVQVILQTPCIIDGLRRCSNSEKLRQEKPGRELVTFLIVCNIAMWIIETFEIKSIYAQQEQVFFYGSILWTLLSHMTLPLTLFYRFHSSVCLVDIWKSAYEAGGNLLYYMREVVCKSVITRLEDTKVIIHLHEFQDEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP43</accession>
    <name>A0A1D2MP43_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lysosomal-associated transmembrane protein 4A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LAPTM4/LAPTM5 transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000756">
        <property type="protein sequence ID" value="ODM94766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP43"/>
    <dbReference type="OMA" id="FCIFCLT"/>
    <dbReference type="OrthoDB" id="10002163at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004687">
        <property type="entry name" value="LAPTM4/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051115">
        <property type="entry name" value="LAPTM_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12479">
        <property type="entry name" value="LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12479:SF10">
        <property type="entry name" value="LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03821">
        <property type="entry name" value="Mtp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="468"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="493" mass="54330" checksum="7D9BD960F70BE0AB" modified="2016-11-30" version="1">MRTPRADPLSSTSSPSSSSQTQHQTTTTRVHQSPRAPPPTRYHINHFDTGGMPVSLWGMDRRDVWRTCFCFHVRTVTIFIGVWYLMMYILALSFHAALLMYEPGQDGFSGGMTVRPEPMLPTPVSNTGAMPPKPVEIPKPESLTIDNSEHHRARVDNMRSGPLTLVLDTSRKATSQVILLTVCNMLITLLMVYGAVRGKPSYLMPFFVLRVFDFCIFCLTMVGYFSYLPNVTEGIMNTQGMPFRDEFLRMDPQLLSFITLIFIVAFIAVKAYIIGVIWNCYKYLMLRNTVIRGVIAYRHDDPTSIMGLQQNLLPDLPDYETAVNDPRYAKKPPPENGQSHPPHTMLVTGGPTTQVGLGVVGMNNSPNLSSNIAMPPPPPYSVAVASEPLHLVIPISGQNLNNNMIDANASNATVTVPQQQPAVISTTTTTTVTEQIQTSGAVDAPTETEEIQTSPIFVPVLPQHLAAEVQQQESSAPVIAADSVPTASHHHHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPG0</accession>
    <name>A0A1D2MPG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ras-related protein Rab-40C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_11765</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000734">
        <property type="protein sequence ID" value="ODM94913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPG0"/>
    <dbReference type="STRING" id="48709.A0A1D2MPG0"/>
    <dbReference type="OMA" id="HKRNSFR"/>
    <dbReference type="OrthoDB" id="6339763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001149">
        <property type="entry name" value="Rab40, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.750.20">
        <property type="entry name" value="SOCS box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001496">
        <property type="entry name" value="SOCS_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036036">
        <property type="entry name" value="SOCS_box-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07525">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00253">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00969">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158235">
        <property type="entry name" value="SOCS box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50225">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SOCS box" evidence="10">
        <location>
            <begin position="183"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="30510" checksum="F0E72C9231E69C1B" modified="2016-11-30" version="1">MCSGSRVNKNYDYLLKFLLVGDSDVGKQEILNSFQDGSLESPFCSGSSPAAYKTTTVLLDGKKVKLQVWDTSGQGRFCTIIRSYSRGAQGILLVYDITNKWSFDGLDRWLQEVEEHAPGVPKVLIGNRLHLEFKRQVSVLDAEEYAIKHKMGFFEVSPLCNFNIMESFVELSRMALQRNGMERLWRSNKVLKLKELCCRAIVSHTTVYGIEQLPLPNNLKSYLKSYAMNRYSTQYRSLPTKFPSKKLKFLTPSDAANTSCATKKSCVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPJ0</accession>
    <name>A0A1D2MPJ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_11662</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000720">
        <property type="protein sequence ID" value="ODM95020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPJ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MPJ0"/>
    <dbReference type="OMA" id="IYCTERR"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF22">
        <property type="entry name" value="PROCTOLIN RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904349" evidence="8">
        <location>
            <begin position="22"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="9">
        <location>
            <begin position="93"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="48028" checksum="19BCF04105076616" modified="2016-11-30" version="1">MNKLVCFAFVVTTPFLISAIADISEDKSFPVDPYIKEHHHLNNYNLPVLPLNFSGGEIGTAKPQNWEVIFKDSSRFWIQFIIFPVVALVGVIGNVGTIYNLSRKAMHSSTNLYLTALALSDLVYLLFSFSMSWRHIPIIKNIWLYWWYTPLGLWVTDASSSTSVWLTVSFTVERYIAVCHPMKKKIYCTERRAFGVSILVCIACIALTATTPLEWRAAVDFNQTKSFNDTSYILEITEFGKSETYRLFYHWFTTIVFVILPLVILSILNFFLIKTVRISRLQRMVMINEKLASVLNLQATRVENRITVTLIAVVILFLVCQIPTALVLIYTSIHLPERGSDEESLLLGLGNICNLLVAINAASNFLLYTELWGKYRKNLSRYFYSKDKTQRGSVGEEKGRAESKTKEQSVGYKNEIQTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ12</accession>
    <name>A0A1D2MQ12_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tropomyosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tropomyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000711">
        <property type="protein sequence ID" value="ODM95106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ12"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ12"/>
    <dbReference type="OMA" id="HHARESE"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000001">
        <property type="entry name" value="Tropomyosin alpha-1 chain isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19269">
        <property type="entry name" value="TROPOMYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00194">
        <property type="entry name" value="TROPOMYOSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="141"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="30259" checksum="1FA7CEA873EFEAAB" modified="2016-11-30" version="1">MEAIKKKMQHMKTEKDNAQDKADTMEQAARDANLKVQRTNEEVDTLKKRLVQLEQEHKVAQETLTQVTTTLEAREKALTAAELELNSLGRKVQQIEETFENTEEKLKAANDSLVTVAHAGDDSERMRKVLENRSATDEERMKSLEVSLKEATARAEEGDRNCDEVAQKKILELEEELKVVGNNLKSLEVSEEKARQTEIEFKSTIKNLTAKLKQAEARAEFAERTVQKLLKEVDRIEDELKNEQERFKSITTELETTFSEMTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRP3</accession>
    <name>A0A1D2MRP3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">mRNA-decapping enzyme 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11087</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000647">
        <property type="protein sequence ID" value="ODM95592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRP3"/>
    <dbReference type="STRING" id="48709.A0A1D2MRP3"/>
    <dbReference type="OMA" id="NASIFNM"/>
    <dbReference type="OrthoDB" id="440673at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031953">
        <property type="entry name" value="mRNA_decap_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16741">
        <property type="entry name" value="mRNA_decap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA-decapping enzyme C-terminal" evidence="7">
        <location>
            <begin position="381"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="424" mass="46188" checksum="DC1B64168C6556C5" modified="2016-11-30" version="1" fragment="single">NVAPKYGLVVMNRKSVSNFIQCFGPDGQVVLNTPFLLLRAVEDLNNDPNDGTQAIHCIWFYDGQECVTSANILKNMGLKFEDETQTHGGMGFGTPSDINKTPGGKLCGNTLFQILQQGSKDSSQQKGKSVAKVMTAEELESQMLHESDHQAIGGTGVLNAAQVNGSSVLHQFLNISIKDKNESKTSGEEVSSSSPSVAHVPLTQNKMRTVEQLEREMRKERSSDSSTSTGSASAVAIQNELMQTLGIPNLTAVDKTDFGDVQSGGYTASPFHTISKSVERTMLDNIVGKSVDETDPEDLRQVLQNIEPSNLILVTENVPGANEARLTWRINRSSSLRKETDSTFTTPTGEFVSATGTRCSSQLGSDPRYFEGSSRPLEVKPSPLTKDQLAQSLIYLLQSDSDFIAKIHDAYVKSLQDAYDGRHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS15</accession>
    <name>A0A1D2MS15_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_10995</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000634">
        <property type="protein sequence ID" value="ODM95691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS15"/>
    <dbReference type="STRING" id="48709.A0A1D2MS15"/>
    <dbReference type="OMA" id="VECAAIS"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10324">
        <property type="entry name" value="SLC6sbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM95691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="616" mass="68815" checksum="3834DA71E79CFD77" modified="2016-11-30" version="1" fragment="single">NSSLYHDNEGYIRDGSEDLVDYTVAAVDPAPRKYIPRIVCDLILLLFFKENTDDGPGDDRDTWDNPLEFLLSCISMSVGLGNVWRFPGVAARNGGGAFLIPYLIILLLVGRPLYYLEMCIGQFSRFGQVKVWNMSPIFKGIGYGAITGTIAQLSYYCSLMAITLYFLVASFAKDLPWAVCDDTDKDYNCTAIGPENYADNYYNKDVFPKKANIDDGLGNLNWKLSLCLVSVWVLVFFTLVKGVKSSGKVAYFTAIFPYVVLIILLVRGLTLKGAWEGIKYFITPEWSALYKPRYVWYAAVSQCFFSLTTGFGPIIMFSSYNPFRQDVYKDALIISFIDTFTSLLAGCTIFSVMGNLVEESEDLEFSDIEGGPGLAFVLYPQAIAKFGWAPQFFAVMFFLMLLTLGLGSAASLAGAVITIICDQFPIWKRWLVTLIVCICGCLVGLMYVTEGGTLMLDLIDNYGAGFIVYVMAMVECAAISYVYGLSNICNDIEFMLGRHVGIYWRVCWSFVIPVGLAANLLYFLITEPEFKSGSVSYPKVATICGWLLTGFAAALIPAWAIHTVATRKAKSLKEKIIEASKPTHRWGPQKKQLRSEWLAFRAEKDAKRSKKRFLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS60</accession>
    <name>A0A1D2MS60_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">YY1-associated factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10759</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000606">
        <property type="protein sequence ID" value="ODM95920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS60"/>
    <dbReference type="STRING" id="48709.A0A1D2MS60"/>
    <dbReference type="OMA" id="TADHHSQ"/>
    <dbReference type="OrthoDB" id="10063208at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039958">
        <property type="entry name" value="RYBP/YAF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033774">
        <property type="entry name" value="YAF2_RYBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12920:SF4">
        <property type="entry name" value="GEO03726P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12920">
        <property type="entry name" value="RYBP AND YAF2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17219">
        <property type="entry name" value="YAF2_RYBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="10">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="64"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="142"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM95920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="20230" checksum="1108B61EAA787EDD" modified="2016-11-30" version="1">MDSKKNSQRQKRQSKTLEENFWDCSVCTFRNTAEAFKCAMCDVRKGTSTRKPRLNPQLVAQQVAQQLTASVPKPARTDGSKERERKSHNNSTGTPEEREKKKKKIRNIRPRLKNIDRSQVHCQPVTVNNVTVVITEFLPKSVASSSQNSTVLPNDIPSSSDVSNHSEVSVNGEVPPTPQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS93</accession>
    <name>A0A1D2MS93_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Leukocyte elastase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10801</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000611">
        <property type="protein sequence ID" value="ODM95876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS93"/>
    <dbReference type="STRING" id="48709.A0A1D2MS93"/>
    <dbReference type="OMA" id="MPRFNIE"/>
    <dbReference type="OrthoDB" id="9518664at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19601">
        <property type="entry name" value="serpin42Da-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904471" evidence="5">
        <location>
            <begin position="27"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="6">
        <location>
            <begin position="38"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="414" mass="46962" checksum="35F54CBBC46716B2" modified="2016-11-30" version="1">MGQSRNLQNFFGISLTILVIAQTAHCQVLSTDNNAVSLKAFQTLWNSNKGSLIASPFSLRTMMAMLMAGARGNTREQIKSVMNFPADEEKLFTTYQEYIHQLNSPSEVKTEVASRIFLKDGYLVQENFQNILKHYFQSPLQQISFDKPKKAAEEINNFVSSKTNHRIQKIVDSSDLTNQTRMVLVNTLYFKGAWENPFPTTSTRRMPFFLDETRNVTVDMMRLETYYRAVDIKQLDCKAVLIPYQKTKKEEDTFQMVILLPNKKSGLASLEKGLTDFGLVDQVFNVRPRNIELRMPRFNIESSLELIEPLKQMGITDVFDENKSDLGGIPTVSKATTKEDKKENQLYVSKVVQKAFLTVDEAGSEAGAATLSVVFVPLSIGPPVEEVITVNRPFLGFIRDARTKTILFTFKKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTI7</accession>
    <name>A0A1D2MTI7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Dynein heavy chain 5, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_10573</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000578">
        <property type="protein sequence ID" value="ODM96104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MTI7"/>
    <dbReference type="OMA" id="REWEAYI"/>
    <dbReference type="OrthoDB" id="286107at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain tail" evidence="14">
        <location>
            <begin position="301"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain linker" evidence="15">
        <location>
            <begin position="1441"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM96104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1604" mass="187778" checksum="3AB5592740647CA8" modified="2016-11-30" version="1">MIDRFDAMGSDEGDDDDDDMRQKSSRKIRLPSGQSSPKGDGTKDDKRKHSVAAHLQAEQNKQKILKAKQERENRRNALDTQHQHLIDVIAYFTDQKPKDVEEFVIDCQEYIDLMEFFFDKQGTKSLMFYFQDHDPPSNESGRTGLPTPGAKKEKMKRVMITSGTDIPLKGLCMYFLRPNSGVKIGMKNVSDECYFGMVTLRDPDEPGIVLDTLNDILQTIYFKNLKGNTTWVTVPDADMATRIRHRFLTAITHYSEFLTDCKNDISSRLDLKEISNLDDISETAIKTTDDILEASKNPDVVQKIEHAVILWCKNIERVLAISKQMRKETDSMGPLAELAYWRNLMAKMCYIIQQTQEWQLVNYIQVLLQAKSRVLRRWKDVDSRVSDEYHESKDNVRYMYALEKFCQPLYQHDPPGMIEHINSMMYTIRTIHTTSRYYNTCEKVTALMVKISNQMVASCRRYLTNDGAETIWSQDKHSMVEKLLKCIELYETYRGSYEATKAELANNPDGKRFDFSVNNIFGRFERFCERLKKIIKIEEIFNLYNPVHESHIDGLEDISARLITLQKEIQLKSYDPLEFRQPDFDEDFVKLEGFMDSAIEGCPTAMHGLWLLERFKNLRNRCLDIDAKLWYLFQFYHNEIILIQQIYEAEKNDTPTPRGYPPFAGKISWARHLYKRLERPMKWFQEKTDVLKRDGATPTVKLFNSVAKKLIFYEILFHESWMTQCNSVYDALEAPILTLRGNMRQELVLNFDPFFRQIIEETEILRKMELEIPDIAQVVYYKKEKLYATYERIKGLLERFLGMKSKIPQDLALLMRPIMKKVEKAFMPGVTNINWTSFKTEEYFNYIEAHQNELEDVIRKLQEIITIRINQVLYDISHTMLIDIPDDRAMPQEEFLDKIHRYGGLVSQDLEYKSRICEHAVVELIHALLTSCELPMPDDPYNAWLSGAGAVPLPGEDSNAKSGGQDKPLIDPTLIPTQMTKEEMVHIYEECRHVFGFYNQKCIEALQKTARISLDILRTRTEEPQVSKRNPGKVLNRVPLFFADLTLTIPTITLKPTLNEMQQALSRGIQLICECLKRVIIWGQIRRSSFAQDAETPFYKDPTKGGQSHDEPVAQFARLQPADAYLRASMQVDNLNARLKNCFKPVMEHKDVSKLVLMMQTVVQQAKPRVQTIISQYMHYNFLWKDTREDEVEAVVATDPVITEIEAIMRTYKELDEEIDAIPQSHRAGPMDILTKEMKLGFRCEVKEWRLAYCRQLSNKYKVICQQIAKFVEECNKELQIPIKDMNDLYSVMSTLIKIRENMYKNDSMLQPIEECYAFLNSQKYRVPDDESNRADTLRYNFNKMLAKAFQTQDKIVSLQDTNRKKLIEQVAKFQQDLKQYLDRYQTKGPMKDGLSVEVATDRLFTFQDEFDELWERYTMCNSGEKLFGFPRNEYPEIYVVKKQLALLQKLYSLYNEFLRTMNSYHEFRWPEVDTTKVIADMENFQTRCIMLPKALKEWQAFKILNKKVNDLNDWCPLVELMTNKGMKDRHWDKLSKATGFKFDLDNENFTLKVVMENPLLKYKAEVEEICNSAIKEKEIEEKMRQLEMMNEFDDGEGGFMDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU76</accession>
    <name>A0A1D2MU76_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_10203</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000536">
        <property type="protein sequence ID" value="ODM96482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU76"/>
    <dbReference type="STRING" id="48709.A0A1D2MU76"/>
    <dbReference type="OMA" id="NRYTDLN"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071243">
        <property type="term" value="P:cellular response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071276">
        <property type="term" value="P:cellular response to cadmium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034614">
        <property type="term" value="P:cellular response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008340">
        <property type="term" value="P:determination of adult lifespan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003007">
        <property type="term" value="P:heart morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006955">
        <property type="term" value="P:immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038001">
        <property type="term" value="P:paracrine signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045793">
        <property type="term" value="P:positive regulation of cell size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048082">
        <property type="term" value="P:regulation of adult chitin-containing cuticle pigmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900407">
        <property type="term" value="P:regulation of cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031347">
        <property type="term" value="P:regulation of defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050776">
        <property type="term" value="P:regulation of immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006970">
        <property type="term" value="P:response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07851">
        <property type="entry name" value="STKc_p38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000063">
        <property type="entry name" value="Mitogen-activated protein kinase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000769">
        <property type="entry name" value="Mitogen-activated protein kinase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008352">
        <property type="entry name" value="MAPK_HOG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01773">
        <property type="entry name" value="P38MAPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="23"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM96482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="367" mass="41711" checksum="FCD042D4A83557B6" modified="2016-11-30" version="1">MSNTRSFYTLELNKTQWTLPETYRDLTPVGSGAYGQVCSSVVVRTDEGSTTTTDAEKVAIKKLARPFQSATHAKRTYRELRMLKHMNHENVIGLIDVFTPSTTPDSSFQDVYLMTPLMGADLNNIIKTQKLSDEHVQFLIYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARPTEMEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIFAECLTGRVLFPGTDHIDQLIRILALVGTPQDDLLARLCSQEARVYIRSLPPMKKKDFNSVFKGANPLAIDLLEKMLELDSEERITAELALAHPYLAQYADPSDEPVSPAYDQSFEDMEAPLETWRQLVFDEIISFVPNPNNPSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUN2</accession>
    <name>A0A1D2MUN2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase TIC 32, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000506">
        <property type="protein sequence ID" value="ODM96753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUN2"/>
    <dbReference type="STRING" id="48709.A0A1D2MUN2"/>
    <dbReference type="OMA" id="GVECHLA"/>
    <dbReference type="OrthoDB" id="9989144at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="38336" checksum="4FBAD4CC125C62A8" modified="2016-11-30" version="1">MCALSVSSKPPGIWYKRLHAYVVYDIFYMVVAGVIALWNEFTVRPPILQVEQIAKRTGHVAVLTGGPRGLALGLIKTLVQLDYNVVMGVRDVDDSQRRLDEFSKSNPDLSLKKITFLEMDLKSLQSVRKFADGLLNKVSRIDLLLCNAAVMKSPYELTKDGFESQFQVNYLSHFLLTHLLLGKIKATAAMKSSPCQIIFTSSMMYAFGRVDFNELEKSAVYTSTKAYLPTKLCQVMGMLTFQKQLLEDDAQVYCYAVHPGLIPTDLWLEAGGPFIARVAQLINGIFRTVKNGADTILWPAFGAEYQNQGGLYLESGKSVNIASKALDKEVQAKLNSKSKELAGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV47</accession>
    <name>A0A1D2MV47_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GCN5-related N-acetyltransferase Rv2170-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000502">
        <property type="protein sequence ID" value="ODM96791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV47"/>
    <dbReference type="STRING" id="48709.A0A1D2MV47"/>
    <dbReference type="OrthoDB" id="61870at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053225">
        <property type="entry name" value="Acyl-CoA_N-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="GCN5-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958:SF6">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCN5-related N-acetyltransferase Rv2170-like" evidence="1">
        <location>
            <begin position="225"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="33574" checksum="DEC7660A77A6DA07" modified="2016-11-30" version="1">MPAPQVVVKVSSEDYTKLEKVLSSRLPSSGMIYNVLKLGQSLTAKGRISVRIFADGTSEKWSPDTSTFMGVANVKGLPQNLVVICGPQNGSSKDTILQLLSVLDWTRENQFEGIDNFIAPIVIDEAKRLGELEENDPIGLYYMHKEDALHIFNDKDNKVLSTSSMQVSSLLPSDAAMVEDRWPEKRKGYLEMLEASIESCSSGGVYLTKDELINAKVNDKSEPDLVSFAVALPFGSIHAFHTETDHRRKGYGKLAMKILAQNIAKAGRVPLVQIFKTNDGSKALNEGIGFKYSHDINLLHFTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV53</accession>
    <name>A0A1D2MV53_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000521">
        <property type="protein sequence ID" value="ODM96595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV53"/>
    <dbReference type="OMA" id="YGLWVVN"/>
    <dbReference type="OrthoDB" id="8267216at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694:SF11">
        <property type="entry name" value="LP21121P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694">
        <property type="entry name" value="PASIFLORA 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="27534" checksum="0A6F00B1F69A4440" modified="2016-11-30" version="1">MGQRKYHPTCHLLSLTMTTKIVALFDMVFGLFGLVWFVLMLSRFGIISLDPFENADTGAANQTDRLDNLRNTDQHTPDKQAFATNHKVINLTLVAFYTAVNLVFFIILLVGVHKRSPGICLIWFHIRCAIFVFKAIILVMYLIGGRPLYSQIPFILSMLAHLYGLWVVNCYVEELRGNIFEKRLEETKTKNEQAVIENSNITDDIPNGIEQIQKKRMQEGLDNPLFHTGENEENKEKSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVE6</accession>
    <name>A0A1D2MVE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000477">
        <property type="protein sequence ID" value="ODM97033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVE6"/>
    <dbReference type="STRING" id="48709.A0A1D2MVE6"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="154" mass="17287" checksum="A671BF8B85E1FFCB" modified="2016-11-30" version="1">MSNRNSYDSHTSTHYSHTTQHLKPPTMVPVIVHHDPHQQPHGGKIGLSASQRQSLILQPAGSRLASDNDTTKIYTSVDTAPSCIEYVAIFLSWLLTIVFFPFAVCSCYKVVREYQRAVIFRMGRLREGGAKGPGTFFILPCVDECYILDLWTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVG0</accession>
    <name>A0A1D2MVG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein Star</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000474">
        <property type="protein sequence ID" value="ODM97077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVG0"/>
    <dbReference type="OrthoDB" id="6357215at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="110"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="423" mass="48678" checksum="807A74D1C6D4B12A" modified="2016-11-30" version="1">MFSKFTTKAFLTFVCIILIALFYNTSFIVYHLTFKNFLHDAINASEIKINLSALEYDDPKLINVIREKFMTRPPISLDERNLTKAVVVGPVTAYVQQLLKNQTNGFFIEAGANDGEFLSNSLPFEVYHGWTGLLVEGDPVPREKLLSIKRNAWAASSCLSPSKKSDQINMVRHKRWNGIGNIPKFFPERLANDFTEPFAVQCFPLYSLLLAIEKFEIDYLSLDLEGSEYAVLESIPFDKINIKVISVEINPKAYPERFFKIRQLLTKNGYRMRKMIQAPLSTSLEWKTFIKKHKFTLRSSINCLFCLDKIVKLEVREDDDSQKTRVPNFKVVCEYVVGRNSKLNSFCGGVEVVRCLCMNCYELAVKITKLHEEIEKAAVEIRVIIQQNETEASSREESSVLVTLETYITLYILACKYIFYRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVQ9</accession>
    <name>A0A1D2MVQ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kunitz-type serine protease inhibitor textilinin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_09531</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000468">
        <property type="protein sequence ID" value="ODM97149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVQ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MVQ9"/>
    <dbReference type="OrthoDB" id="7870222at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF374">
        <property type="entry name" value="BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904622" evidence="5">
        <location>
            <begin position="27"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="6">
        <location>
            <begin position="286"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="128"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM97149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="366" mass="41081" checksum="FC7C6F99F99BE0BF" modified="2016-11-30" version="1">MCRLGILETWLILIVTFIFCVSNAEGSVSSTIKRNTHSREFYNEDYDADSNVKEMVFLRQVHAHDLDESVVVEGHNNIKQSESSSSMSSVNDDFHKGHHHRSTRAVDVDLSNKNTVMAEEYTGKTQSAFDVKVNNDSPASNQKELDSGGNVPANAPGDKHEDLMIPDHDDDDAAHDYAKPQFEEASASAFHKIVQIREFDDHDQASGENDYAEHFGHTSHALRKRSTLSGVRADRSEQKEKADLAMMGKLLAVARQKKEEQSLNENGDKDKAIDIDINQRFPSSFCQLEKSDGNVCSGLGREITVQQFYYDPRKNQCIQFTYSGCGGNANRFSSVSECSRACVDPKLKNKRVENGKTKLFPSKWYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVV4</accession>
    <name>A0A1D2MVV4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000488">
        <property type="protein sequence ID" value="ODM96924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVV4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="497" mass="57876" checksum="B284D88713505E89" modified="2016-11-30" version="1">MLPNKLVVAMMLSVWGKHLQFAQLYLETTEVNHLAIDNLDQLNLFVDIPMNATARAEWKELRANVTNLFDLNENFTDKILEHFEPLEELLVPWLGLAHSVLKNPNLEETQLMEIYKQFLKNKHVRQLSNMEISTFQTEWDQLNLLQRLEDYHEQILVLKGVVTNSRAQKVDDSLLSRQTAKRDSIHGLLKKQVQIGQLRLETTEFGHLVDEINEKLAAITESTTTTLKTRKKILEVRYEVIELMKLHAEFDAKTKDYCQLVAAEDFLALWVHVFQTTRQNPHFDDEDLEEFAQPLLSNENVRRFMRLDVSQLLSEWKQMNLSERMHRCSDTVRDLVAGLPNEKVTESEILATLLVKQENVGELINQCNVLLRILNEIGAVFEKMSNYLEIHIKLQPISYKIMDIWKEFEVYQPKIMTTFETLGKAVKLLAKKGTDELIESGQFFSDESIQEAFKIDIETLQKDWTRMDLIERAKSCQAEVKTVKAQGDRIYQRASEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW04</accession>
    <name>A0A1D2MW04_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000496">
        <property type="protein sequence ID" value="ODM96855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW04"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="202" mass="22325" checksum="66A4BBCDEA35CE97" modified="2016-11-30" version="1">MHRKGGGSSVDSIRKSYPKRARKRSNSDEGSSDGEHTLELASSHSSDEDEATPKAKLRSATLDLKPSVGVPSSGSDNEASINNYKYPVTDEESTYQPSHKELNSRENLHNLGQGTELKYEEKLPFIYQGGDPVNDLSGTTVAHPLSSSEGGQQQLALHRHFTYGESGMHHMQQQPIHSHYGLYWSPSTDFRITHSNSSRTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW83</accession>
    <name>A0A1D2MW83_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">cholesterol 7-desaturase</fullName>
            <ecNumber evidence="14">1.14.19.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_09462</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>cholesterol + NADH + O2 + H(+) = 7-dehydrocholesterol + NAD(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:51644"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
            <dbReference type="ChEBI" id="CHEBI:17759"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.19.21"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:51645"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>cholesterol + NADPH + O2 + H(+) = 7-dehydrocholesterol + NADP(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:45024"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
            <dbReference type="ChEBI" id="CHEBI:17759"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.19.21"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:45025"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Hormone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Steroid hormone biosynthesis; dafachronic acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cholesterol 7-desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.21" evidence="14"/>
    <dbReference type="EMBL" id="LJIJ01000462">
        <property type="protein sequence ID" value="ODM97218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW83"/>
    <dbReference type="STRING" id="48709.A0A1D2MW83"/>
    <dbReference type="OMA" id="NGWIPVM"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="UniPathway" id="UPA01020"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170056">
        <property type="term" value="F:cholesterol 7-desaturase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045605">
        <property type="entry name" value="KshA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19298">
        <property type="entry name" value="KshA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Rieske" evidence="17">
        <location>
            <begin position="52"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM97218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="379" mass="43690" checksum="2FCF65AE016D4DE9" modified="2016-11-30" version="1" fragment="single">PYDLFRDYTELGFEHVTGRHQFGNDLIKRQQINWHMKRRKIGDLPPAYPNGWFAIFESDELVTNTVKEVYALGLNLVAWRGKSGKAYVSDAYCPHLGAHLGVDGIVRDECIQCPFHGWKFDGCSGKLMRIPNIDSVPAAKLKMWTVHESSGFWPDICEEVENGEWKYRGRSEFRVACHIQEIPENGPDSGHLNVVHSSLVTEGSVPNESWVKWKFLKHVFSATWTPNTENGREHEALMLVNHHLLLFNKIPFVNVSVKVSQIGPGIVQMHFDTIFGKGILVQNVTPLGPMMQRVVHRFYSAPTFIHPLGLLVLQSEGVQFSRDVRIWNRKTFLRIPLLTKEDKQIRTFRRWYSQFYSENSPKLKVRSETDDCKNGRLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWM7</accession>
    <name>A0A1D2MWM7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000440">
        <property type="protein sequence ID" value="ODM97453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWM7"/>
    <dbReference type="STRING" id="48709.A0A1D2MWM7"/>
    <dbReference type="OMA" id="ISCHIID"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF176">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="175"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="340" mass="37294" checksum="05131D0545F6F929" modified="2016-11-30" version="1">MTVLDRFEIVLEDPGRGYKPDEEVSGRVVLKAKAGEVESKGLTIKFTGKSIIIGRSGGKKGRRLQNYFDTTPIFLVGDGSSAVEVVKSGQQISFPFSFQLPCGCQLLPLPSSLEAQWGNVEYYLEAELDLTPYKKNETAFKSVQVISPLNLNYIPEIIAPVQAEASKTFCCTCSGMGSLTLTVTLPKGGFTPEEKIPFQVKVENKSGRKIKRLTAAVGERIHYRRFSDIKTRYEKDFGALLSDDGFIVRPGDTGFWSGELEIPQLPPTTTLEHESVIIGVEYFFVVQARASGVSKRFPVFCPIVIGTVPIPLDSTASIRSERIQGAGENVSRPVSRTSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWR5</accession>
    <name>A0A1D2MWR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000438">
        <property type="protein sequence ID" value="ODM97486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWR5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="32381" checksum="DAD5730D2236B88E" modified="2016-11-30" version="1">MYKSEDAAGHRTTIGFTALERLTRSRSSSSIYNSDACDSPRSWLAGPSVLASLIFVTNKPPSSLSVEHCDLIRNSISPVRMNNKMLHRGPLDRLTTFTHLPVLSTCVLLLIQFQIFHALPTSVASLSSFSSVQTSVNTQEASPSSFVYSPTYSYSSYRPYALQQYAASVAHPNSVYSSQSVSPLSESKLGQLIKERETIQLNNAEKKVTIVEIDQEIPSQKLNRAQQPRLSPLPLPVPENEKKPSEEVLAEEQRSVELSYPPPFAPELDPQYERRQSGLGPISLLDQAGPFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXZ6</accession>
    <name>A0A1D2MXZ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette sub-family A member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08802</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000399">
        <property type="protein sequence ID" value="ODM97870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MXZ6"/>
    <dbReference type="OrthoDB" id="6512918at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002470">
        <property type="entry name" value="ABC transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000298">
        <property type="entry name" value="ATP-binding cassette sub-family A member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056264">
        <property type="entry name" value="R2_ABCA1-4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23321">
        <property type="entry name" value="R1_ABCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="818"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="985"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1025"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1064"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1093"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1197"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="457"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1261"/>
            <end position="1492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1603" mass="179249" checksum="A36328F04D5EC572" modified="2016-11-30" version="1">MLIYYAPDTPIIQKLMDSVQAKFFNNTELQYSFRGFDTEEELLRAYTNSSTSMYAETEEGTLSSTVLAGIVFRNITGTEFPEKIDYSIRFPAALRSESGLLGERFSFGMKQAWFTEILYPIIQTFGPRAKDQLTGGEPGYWSEGFVYVQYAIESELTFTITGETQTILLQRFPYPAYDDDEFLVILQPFLPLVLVLSFLYSVLSIARTLVTEKEKRIHESMKMMGLTNTLHTTASFITFFALVSVSMLLITILLKIPLYTDPQGFGVSVLPKSSASVIYFCLLVHGFQLISFGFFISRVCKTANAAAISSSIIWFMLFLPFPFLQPRYSILCTKIKMVWSLLTNMGICFCCQVFCMKESTSQGLSWNNMFEGVTPDDTFSIGDCIIVMIVNGIVYFVAALYLGIVFVGEFGPTARPWYFFVTREFWGTRNVEMSKVETSSYKSEFHERTPKSLVPGIQIRNLTKTYGEVNALQRLNLTMFQNETFCLLGKNGAGKSSLINVLTGLYPPTSGTAVINSQDIRTNMTAIRRTLGVCPQHNILFDELTVEEHLQFFTTLKGMKGKAMMEEVNRMIIAIGLCHKRKSQVKTLSGGMSRRLCIGIAFCGGSQVIILDEPSTGLDVEARRAIWDLILAEKVGRTVLLSTHFMEEAELLGDRIAILVQGALICSGSSLYLNKLYNGGYNVTVVMEEENGSGKEQLTDFIRDYVPEAMPIRSAGKELTFSLPENKSTEFPALFDAIETQQRELGVESFGARLTSMEDIFIRVNGEQEIEVRNGTQDTLQFVGLSDEETNEGAKLLLQQLHGVVIKKLAYLRATSELFVGQVVIPVVYLGLVLVVIQTIPGIFDPPPHVFELDHYEIFGDTITDVQCADYCSAYESYFDKIRKKVMLVDKNQSYSSTLLDLERQDIAAFNSKHIIGFEEKKSNDTTTLTGFFNNQAFHTPPLTLNAITNALIGNHTVKVSNHPFPYTNLDTQDTGNYWTVGFHVGYNTAFALTFVIAVFSTFLVKERVVGMLALQRISGMNLFVYWAGNFVVDFVNYLVPCAALSGVFWIFSNSTDAFNGDVLKYLILLFLAFGWALIPTVYVMSRCFSIPAVGFAGCGVTCAFSGFITILTITVLELPQVNQINIATVLHRVFLVFPTYALGRGITQLSINKKLVEKCTGFNLEFLCEAAPDSYCCVKMRSNYLDWQEVGIGKNIVYMLCVGVFAIVMLILVESKIFDGVRWGFKNLRSNEKASILNDEDDDVRLERERVEKEGHSDILVIKDLAKSYGPVKAVDNITFGAQEGSCFGLLGTNGAGKSTTFRMLVGETSADSGDAIISSFSVSRERSKTHKLIGYAPQFDALLGELTGRETLVLFARIRGVKERLIRETVENIAKELSFYQYIDRKVEGYSGGNKKKVAVANALIGSPKVVMLDEPSAGMDPVGRRQLWAALRTRMRDKRTCILLTSHSLEECEVMCSRIAIMKNARIQALGSPQQLKHKFGDGFSIVVQLRTNRLEKDRLERKLSTLSQLSATSSISSVEVSQSMQLVDSHLRSHFPASVECELTSSHANYLHYHLKPTHHQSTVSWSTLFRTMETVKDQIGISAYSVSQISLEQVFLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYD6</accession>
    <name>A0A1D2MYD6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Growth hormone-inducible transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08626</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000385">
        <property type="protein sequence ID" value="ODM98056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYD6"/>
    <dbReference type="STRING" id="48709.A0A1D2MYD6"/>
    <dbReference type="OMA" id="WATHCAI"/>
    <dbReference type="OrthoDB" id="6285520at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF112">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="130" mass="13670" checksum="7CA0AFF4BBA61835" modified="2016-11-30" version="1">MVHSGVIGVVLAPLCLLGGPLLIRASYMTAGVVGGLSAIACCAPRSMFVPATTALGAGLYSMSLYGGLLLFSGFLLYDTQRIIKYAETVPPNSVHKYDPINAGMSIYMDTINIFIRIAQILAMGGGGRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYY1</accession>
    <name>A0A1D2MYY1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BTB/POZ domain-containing protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000369">
        <property type="protein sequence ID" value="ODM98256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYY1"/>
    <dbReference type="STRING" id="48709.A0A1D2MYY1"/>
    <dbReference type="OMA" id="LCMINHI"/>
    <dbReference type="OrthoDB" id="9997739at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008344">
        <property type="term" value="P:adult locomotory behavior"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048512">
        <property type="term" value="P:circadian behavior"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050804">
        <property type="term" value="P:modulation of chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18287">
        <property type="entry name" value="BTB_POZ_BTBD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000038">
        <property type="entry name" value="BTB/POZ domain-containing protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000051">
        <property type="entry name" value="BTB/POZ domain-containing protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052407">
        <property type="entry name" value="BTB_POZ_domain_cont_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46306">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46306:SF1">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="42"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="563" mass="63153" checksum="F424A5D6C3FE81B1" modified="2016-11-30" version="1">MSSSGCETRSSSTGKDISCDVDHVIMLSDNMKSSLFLNPEYADVHLIVEGVSFPAHKIILAARSQYFRALLYGGMKESTQSEVELKAATTSAFKSLLKYVYTGRMALGELKEDVILDVLGLCHQWGFEELEASICEFLQAALHVGNVCAILDTALAFGLESLVSTCCVFADANAGTLLDHSTFLLLSPAGVTELISRDSFCAAEEKIFEAVCNWVRSNQDIHQDAATVLNHVRLPLMNLNVLLETVRPTGLVSSDMILDAISAQNKSRDTELKYRGYLVPEENVAHVKHGASVLKGEMRQAILDGDCQNYDVERGFTRHVIDENGEGGGGIVIKLRQQCILNHVRMLLWDRDLRSYSYYIEVSMDQVDWVRVCDHTRYNCRSWQSVFFPQRVVRYIKIVGTHNTVNRMFHVVAVQAFFTKKEFTIDPKWGLVVPKDNVATIELSACVIEGVSRSRNALINGETRGYDWDSGYTCHQLGSGAIVVQLAQPYVISSMRLLLWDCDDRSYSYYIEVSTNQRHWEMVCNRSRESCKSWQTIRFDAIPVVYIRIVGTNNSANEASGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N068</accession>
    <name>A0A1D2N068_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cohesin subunit SA-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_08376</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000365">
        <property type="protein sequence ID" value="ODM98305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N068"/>
    <dbReference type="STRING" id="48709.A0A1D2N068"/>
    <dbReference type="OMA" id="QIQEAAY"/>
    <dbReference type="OrthoDB" id="498590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039662">
        <property type="entry name" value="Cohesin_Scc3/SA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056396">
        <property type="entry name" value="HEAT_SCC3-SA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020839">
        <property type="entry name" value="SCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013721">
        <property type="entry name" value="STAG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11199:SF0">
        <property type="entry name" value="LD34181P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11199">
        <property type="entry name" value="STROMAL ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24571">
        <property type="entry name" value="HEAT_SCC3-SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21581">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08514">
        <property type="entry name" value="STAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51425">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCD" evidence="4">
        <location>
            <begin position="321"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1079"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1105"/>
            <end position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM98305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1122" mass="128271" checksum="7DB47CF1E1FD8672" modified="2016-11-30" version="1">MQWTLPFPAKEIYHILQQICQKQHQRLVYPNTRRRAAAAAASTSVGSTTPARRSKRKVAEEAAAARVETASPTSVDEGTPKRTRRGAASKKQPPPPPIVEQQQVINEDDDDSLYNAILQGKCSLQQLVDDWIEDYKGNRDSALLRLNQFFISGSGCKGKITPQMATMEQPAIIRKMTEEFDEDSGEYPLVMSGQQWKKFKGNYCDFVQTLVKQCQYSIIYDQYLMDNVISLLTGLSDSQVRAFRHTATLAAMKLMTALVDVALTVSINLDNTQRQYDSERQKTSVKRAAERLEALMGKRQELEENMDEIKNMLTYMFKSVFVHRYRDTLPEIRAICMAEIGVWMKKFHQNFLDDSYLKYIGWTLHDKVGEVRLKCLQALQPLYASEELKGKLELFTSKFKDRIVAMTLDKEYDVAVQAVKLVILIHKYHREILTDKDCELVYELVYSSHRAVAQAAGEFLNERLFVIDEGAVENIRTARGKQRLPNTPLIRDLVQFFIESELHEHGAYLVDSLIESNPMMKDWECMTDLLLEEPGPAEEPLDDKQESSLIEIMVCAVRQCATGEPPIGRGPTRKILSAKELKQVSDDKNRLTEHFIPILPALLTRFKADPDKVANLLSLPQYFDLEIYTTSRQEKSLDMLLELIKDVVEQHTEMEVLETSAKTLEIICCDDARKSSRTEVALMNVLESLWDKALDGIIDYENNVQDGGEADEDDLYNINMSLRKISVFYGCHSFDKWDVWAKLFRIIKTTVDNIAEYPAESVKHAISACYFALLWDLKNIQEKGEHGVSGTDDVPKLHRKLNDYMAAMKVLVSHTEAPHSFREEAYTSICDGLIIFCEQLNTQKWMETLVYQPDQDLQRLLNKFMQDNVFSELRDDELDEHARIELLHKMRNYLAQFCKLIVYNVMPISAAADVFKYYVKHYNDYGDIIKATLGKAREINKVNCALTMIVSLTSVFADLPKVNTWMVDRQCDEFNALKDLAKRFALSFGLDAIKNREAITALHREGILYSVNPLENPIDSTGPPPNLAFLEILAEFTNKLLKQDKRVVLQYLDSRVGSAVPSSQGAQWQPLYTYRNSLMHGESDKDNQPQFSKRAYTRKRQVQDGDVDQDDVDADPDDADAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Q2</accession>
    <name>A0A1D2N0Q2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein tilB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07888</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tilB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000321">
        <property type="protein sequence ID" value="ODM98810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0Q2"/>
    <dbReference type="STRING" id="48709.A0A1D2N0Q2"/>
    <dbReference type="OMA" id="QHRAVIV"/>
    <dbReference type="OrthoDB" id="10250990at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000052">
        <property type="entry name" value="Leucine rich repeat containing 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056496">
        <property type="entry name" value="CS_DNAAF11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23602">
        <property type="entry name" value="CS_DNAAF11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein axonemal assembly factor 11-like CS" evidence="10">
        <location>
            <begin position="231"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="180"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="400"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="450" mass="50996" checksum="5419FF2123978906" modified="2016-11-30" version="1">MGRITMQLLRKRSEHNEGEIHSLEELALHQEKLENIELIDKVCRNLKILLLQNNAISKIENVGRLKNLEYLNLALNSVEKIENLEGCESLKKLDLTLNFVAELTSVKSISGLPHLEQLYLVGNPCHDFPGYRDYVVGALPHLQSLDGREITRAERITASQNHEELEQFIIKLQEEYLSSQDRNGPENLDLSPKESSETVISEKQSVDDNEGDDDDSEFWTQKSANTPQVRKEMVRRIEKQEAKKNPKETKKVKPPRKLTNAEGKPLNINEAKVSFSLHDECERSQLVLDLAVPKFMCTTLIHADVQPFHVKVTMKGKIFQLVLPEEVKPDSSYAQRSQATGHLIVTMPKVYDTSTMVWQGKDAQSTEIVDLTNRINSAGDSAKRNKFAQAKSSVLTLKSKLSPKTSPRENTDSTTRNSVTPKERKGILKKNYEDKDQAKIVDLEEVPPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2N0</accession>
    <name>A0A1D2N2N0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000274">
        <property type="protein sequence ID" value="ODM99518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2N0"/>
    <dbReference type="STRING" id="48709.A0A1D2N2N0"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="70" mass="8059" checksum="FEADAAB159C8EA27" modified="2016-11-30" version="1">MLLSPTVEKRHAVLAFEPKSNGFTVRDLNTTNGTYLNHRRISADHPETVFNLDLLRFGYDIHFIQNCKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2P1</accession>
    <name>A0A1D2N2P1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein sleepless</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000271">
        <property type="protein sequence ID" value="ODM99553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2P1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904936" description="Protein sleepless" evidence="1">
        <location>
            <begin position="37"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20280" checksum="4542E80A9BD814C0" modified="2016-11-30" version="1">MILKACVLKPTHSELYPISLTVLFLLLSLFICSISGSSPSASPPAPSLNATICAVCESFTEPTCSDDKALITGNNFTMECELPEIWCFKSEGNITTKDHNGHSISMKKVERGCTKERNNEECVRIKQKDNSDFKVCYCRNATCNIDFDISSLTPINPNGGEWTGNNLWNIWWLILSALIAHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N374</accession>
    <name>A0A1D2N374_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nuclease EXOG, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06949</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000259">
        <property type="protein sequence ID" value="ODM99726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N374"/>
    <dbReference type="STRING" id="48709.A0A1D2N374"/>
    <dbReference type="OMA" id="CERAPQW"/>
    <dbReference type="OrthoDB" id="5960141at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.570.10:FF:000007">
        <property type="entry name" value="Alkaline nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF19">
        <property type="entry name" value="NUCLEASE EXOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904963" evidence="6">
        <location>
            <begin position="26"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="7">
        <location>
            <begin position="69"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM99726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="36897" checksum="4A5CE1581557168A" modified="2016-11-30" version="1">MISFAGKGVLVLAFLQLLCLREILSGTIKESLRDYEDLDYLAGETLHRVGTCDNNKTLVEIRFDSDNPPVTLITLCHDEDLDFTLWAKSYIFGEDLENSEGGGNRPSFKEGDFYPTISADDCYKQVTQTETIGMLVGSTSLAQHYVQTSKNLFLSRGHLTPNGDPITAVQKAATFYFINVSPQWQTINGGNWVSLEMAARELAGNALSTFTVWTGSYGVSTLDDVNGNPVEIWLGRSSSGALVKKLPVNHLTWKVIYDETTRTGVAVIQINNPWVESVTDDDILCDDVCDQLSWVNWDTKDIVKGYTYCCTVASFKQKVSYAPELGDIPLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3A7</accession>
    <name>A0A1D2N3A7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000256">
        <property type="protein sequence ID" value="ODM99766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3A7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17534" checksum="72B6901687AF0374" modified="2016-11-30" version="1">MVSCSYTYGVTALMLVVLTLTMFVIGVARIRFFSRWRRIFSRSDVAERKPNRGNNEPINFNSINYSTLLLTLTMLPTSVLVLVIVYCVADSIDIEPPFDDEEGSVDVDGIGFPLLIATIEIVMLICFAIAICATCCWKKVTTTYSTRNTGNKDVENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3M2</accession>
    <name>A0A1D2N3M2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_06807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000250">
        <property type="protein sequence ID" value="ODM99876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3M2"/>
    <dbReference type="OMA" id="CEITYIE"/>
    <dbReference type="OrthoDB" id="6106100at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="67" mass="7758" checksum="064313B43625CC91" modified="2016-11-30" version="1">MARAQLKMEKNSSLAELVINPLMIADEDLYKCEVTYLEAKEHCALLQSIRLNTFATFNSLTYVHYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3M6</accession>
    <name>A0A1D2N3M6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Fat-like cadherin-related tumor suppressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_06848</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000252">
        <property type="protein sequence ID" value="ODM99840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3M6"/>
    <dbReference type="STRING" id="48709.A0A1D2N3M6"/>
    <dbReference type="OMA" id="VAQCKVV"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030855">
        <property type="term" value="P:epithelial cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001736">
        <property type="term" value="P:establishment of planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031175">
        <property type="term" value="P:neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007424">
        <property type="term" value="P:open tracheal system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000013">
        <property type="entry name" value="Cadherin EGF LAG seven-pass G-type receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000020">
        <property type="entry name" value="Dachsous cadherin-related 1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF438">
        <property type="entry name" value="CADHERIN 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="30"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="142"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM99840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="278" mass="30250" checksum="D85C5924A203CF56" modified="2016-11-30" version="1">MNRRESGEACRVDIRIHILDENDHAPKFTESGSYVVTVKEDAPVGALIGKVHADDEDLGVNRKVRYTLLTVVGSSGESMIDDQFGMDGTSGVISLLRPLDRELVSQYNLSIQATDDGIPPMSSLAHMRIILMDVNDNPPVFAFNYYSASISELAPVSSEVTRVLATSKDIGINADITYDIVGGNGYNHFGIHPKTGVIFVSAPLDYERVKEYVLAIRARDGGTPPLASQALVNITLIDMNDNSPVFNVDSYSVEIPEDAPIGASVMQDAYHHQPCILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4M3</accession>
    <name>A0A1D2N4M3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein RFT1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_06460</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Endoplasmic reticulum membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the RFT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000223">
        <property type="protein sequence ID" value="ODN00220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4M3"/>
    <dbReference type="STRING" id="48709.A0A1D2N4M3"/>
    <dbReference type="OMA" id="QANCINI"/>
    <dbReference type="OrthoDB" id="9979195at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034203">
        <property type="term" value="P:glycolipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024135">
        <property type="entry name" value="LAMTOR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007594">
        <property type="entry name" value="RFT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117:SF5">
        <property type="entry name" value="PROTEIN RFT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16672">
        <property type="entry name" value="LAMTOR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04506">
        <property type="entry name" value="Rft-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="460"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN00220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="582" mass="65571" checksum="6F2C4DE4B72AA6D7" modified="2016-11-30" version="1">MERKLEEKMAGIMNKPGVVGAICVDNKGLTLSDDSSSSSDDCEMAGSPKKSPKKAPDEILSGSVRSASFNIIFQVITRVFTFMLNAFILRYVSHDVLGICNVRLALLYSSVMFLSREPFRRAVLRKSESDSWLETINLIWLVIPCTVFWSVFLGLVWCYLLSQPGAFPDSAEAVQYRLSVWVMCFALVVDSFTEVPYILGQYFLFYRLRIVGDTLLIAVRSFCLCIAVVKFPSTAIFSYAFGTLVGVICVSSLYYGYFYYYIHNVARRDLPFGSISALLPRSGLRFPKDLQILAWTFFKQGILKQLLTEGERYMMTFLDVLTFKEQGIYDLVANLGSLAARFVFLPIEESSYSYFAQSLQKQAKSVTRTKELMVEIGAVLGRLVRMMSLVGMVIIVYGLPFSNTVLFLYGGSRLSDEGPGTRLLQANCINIFTLALNGVTEAFTFAAMSKDQMDKFNKRLVWFSGIYLFAAWILTSYFGSIGFFIANSINMSLRIIQSCTLVQLKFSVYKINPFNFWLPKVNTIAVFGMSTIVIWTLSLFDVGRVLFVLVGLVIFATNCLAALYFDKDLTSFFLNIYKTKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4M9</accession>
    <name>A0A1D2N4M9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cardioacceleratory peptide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_06489</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cell membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000225">
        <property type="protein sequence ID" value="ODN00192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4M9"/>
    <dbReference type="STRING" id="48709.A0A1D2N4M9"/>
    <dbReference type="OMA" id="NRLCPPF"/>
    <dbReference type="OrthoDB" id="5987909at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008188">
        <property type="term" value="F:neuropeptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005000">
        <property type="term" value="F:vasopressin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052665">
        <property type="entry name" value="Neuropeptide-GPCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001817">
        <property type="entry name" value="Vasoprsn_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24224">
        <property type="entry name" value="CARDIOACCELERATORY PEPTIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24224:SF6">
        <property type="entry name" value="CARDIOACCELERATORY PEPTIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00896">
        <property type="entry name" value="VASOPRESSINR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="8 10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="63"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="383"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU046427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="464" mass="51978" checksum="9632B2D0F8F7DECD" modified="2016-11-30" version="1">MTKGGPSYNVDTVKPKFCTRNSLSFLRGFTLWVCKSCGCHIVLKEHVETLTFLGILLFFIVIGNSAVLAALMMGKTQRKSRMNFFIMHLALADLAVGLINVVTDIIWKVTVSWYLGNIACKIIKYFQTVVIYASNYVLVALSIDRYDAITHPLKFSGSWRRARLLIATAWGLSFTFSLPSAFLFHEKNIETSFGSTVTQCWIDMKPVEWQVYMTIISIALFIIPAFIIAICYTIMVHTIWTQSRILTPSSKKTSNGIFRRGTCKGAAKTDDDDSRRASSRGLIPKAKIKSVKMTFVIVFVFICCSSPYVVFSLLQVYNFIPRTQTMTALSTFFTSLSPLNSAANPIIYCMFSTHICRNLRKIRIINWFAMRCCPNLGKSSPTTGNKRRFGAGASNQDTSQKRTDFSSLTDSLMSRSDRITQSTIRSSTNNGIRRHEGPGSILNKEVKFQTPNSGTVPHCPQNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5D2</accession>
    <name>A0A1D2N5D2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000204">
        <property type="protein sequence ID" value="ODN00490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5D2"/>
    <dbReference type="STRING" id="48709.A0A1D2N5D2"/>
    <dbReference type="OMA" id="CRNGYMC"/>
    <dbReference type="OrthoDB" id="9979716at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055470">
        <property type="entry name" value="DUF7042"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055472">
        <property type="entry name" value="DUF7044"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255:SF9">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23069">
        <property type="entry name" value="DUF7042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23071">
        <property type="entry name" value="DUF7044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7044" evidence="2">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7042" evidence="1">
        <location>
            <begin position="106"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="370" mass="40904" checksum="8F9A136D4E47ECC8" modified="2016-11-30" version="1">MSAEQCQLPARWEGSWFQSGVHQTITINRSTISTKGRCLESEGEKYLLKNEKDNCFRCVVFHEKHLNVLQYKETFCIPDRSPLRTICSTISGDANLFSMFRLDGAPIDCPFKGPLTFTYNRGHGDCRYPVSTIESCIHPSRVLLNYQACPDIPGTESAVEELQCLAAWKEGSFRYLVGLIQYRHHASYEERFRCFAYEKSKKGGVFSGNYGNFANNSAVSLALGSTSKDSASLVSVPAGGTSSVAVGSMSTNSNNNNNQQNDLLFRVAMSGDASCNGLLPNEGSRTMLFKKGSTPKPCQFPSWVQAHTQWHTLDQRSTYAFDSSTLRVSNSSDPTGISPSTLSMTAVCHQILDNPTLDKVMLVLQSTSEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7S8</accession>
    <name>A0A1D2N7S8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Insulin enhancer protein isl-2b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05348</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000159">
        <property type="protein sequence ID" value="ODN01330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7S8"/>
    <dbReference type="STRING" id="48709.A0A1D2N7S8"/>
    <dbReference type="OrthoDB" id="125004at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007409">
        <property type="term" value="P:axonogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048665">
        <property type="term" value="P:neuron fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000041">
        <property type="entry name" value="insulin gene enhancer protein ISL-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047169">
        <property type="entry name" value="ISL1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24204">
        <property type="entry name" value="INSULIN GENE ENHANCER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24204:SF8">
        <property type="entry name" value="TAILUP, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Homeobox" evidence="12">
        <location>
            <begin position="42"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="9">
        <location>
            <begin position="44"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="13711" checksum="D7576B1B570CCB7F" modified="2016-11-30" version="1">MSQQEVIRLLFSFGFMTDSSESGPPTTGKLREGRGNGKSGEGKPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKAILMKQMQQQEKEVTAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAZ8</accession>
    <name>A0A1D2NAZ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAZ8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="6941" checksum="1E4C6B74C42E0A6A" modified="2016-11-30" version="1">MRGVTSESLTNIYLQKRETMMKPSFPFLENLRFSANTVLLAFLKVKGLTLIFKGNTLGLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBN4</accession>
    <name>A0A1D2NBN4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_04029</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000101">
        <property type="protein sequence ID" value="ODN02658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBN4"/>
    <dbReference type="STRING" id="48709.A0A1D2NBN4"/>
    <dbReference type="OMA" id="FKEEWIA"/>
    <dbReference type="OrthoDB" id="8957712at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000003">
        <property type="entry name" value="TRAF2 and NCK-interacting protein kinase isoform 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000006">
        <property type="entry name" value="TRAF2 and NCK-interacting protein kinase isoform 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051700">
        <property type="entry name" value="STE20_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47096">
        <property type="entry name" value="MISSHAPEN LIKE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47096:SF1">
        <property type="entry name" value="MISSHAPEN LIKE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="24"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="13">
        <location>
            <begin position="565"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="310"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="524"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="430"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="525"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN02658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="881" mass="98520" checksum="55A7B94A46FFA401" modified="2016-11-30" version="1">MAGNINCSLDDIDLASLKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKFSHHRNIATYYGAFIKKSPPGRDDQLWLVMEYCGAGSITDLVKSTRGQSLKEEWIAYVCREILRGLSHLHANKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPEATYDNRSDLWSLGITAIEMAESQPPLCEMHPMRALFLIPRNPPPRLKSKRWSKRFHSFIETVLVKDYTQRPPTDQLLKHPFIRDQPTERQVRIQLKDHIDRCKKRLNQQSKADKGRFSDEEDEDEEGDDKPGERGEEIKPKENTLRRNFQALQVEEPGPPARPPLPSRLIVVPDALPPPPSRPLPPTPGGALEADDVEDDDEEEVEFVPKKRNDGTLLASEAPRPLPAVGPSRPLPPTPEESQGTLVTRRPPRTGNEVPGVRTSVLPDLLPQTSPDPDMSREREPTRPTSHPAIPQPGQIGQGPKQKSFVTFGFGNQMASSASASSSPSRPSVNVNVEGVAPSQGGDTPEIRKYKKRFNSEILCAALWGVNLLIGTENGLMLLDRSGQGKVYQLINRRRFQQMEVLEGQNILVTISGKKNRVRVYYLSWLKGKILRTEGAEWEKRSGYINVGELQGATHFKIVKYERIKFLVIALRDAIEIYAWAPKPYHKFMAFKAFSDLLFKPLLVDLTIEEGSRLKVIYGSAQGFHAVDLDSATVYDLYTPKHVSSQGPITPHCIVTLPNSHGLQLLLCYDNEGVYVSTSGKISKSVVLQWGELPSSVAFIGTGQVMGWGQKAIEIRNVETGHLDGVFMHKKSQRLKFLCERNDKVFFSSAKGAGASQIYFMTLNKPGLANW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBS7</accession>
    <name>A0A1D2NBS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neuroblastoma-amplified sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000111">
        <property type="protein sequence ID" value="ODN02456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBS7"/>
    <dbReference type="STRING" id="48709.A0A1D2NBS7"/>
    <dbReference type="OrthoDB" id="19988at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029145">
        <property type="entry name" value="NBAS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15922:SF2">
        <property type="entry name" value="NBAS SUBUNIT OF NRZ TETHERING COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15922">
        <property type="entry name" value="NEUROBLASTOMA-AMPLIFIED SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15492">
        <property type="entry name" value="Nbas_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neuroblastoma-amplified sequence N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="149" mass="17876" checksum="96DE9B81EEDF92A9" modified="2016-11-30" version="1" fragment="single">EPCIENGITAWRLINDVPHYNLAFTVDTNDFRMDSRNLWSTALSVLTFKQSPTDSVFKLVVSQCSKYIAAIHVSGTISCWCLPSLKLHRNWPLKLQFQYHTENPRFNNRWRLVFNRWNSEPVDDWRFFPYDINWWNETVRNSFISRSHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBX2</accession>
    <name>A0A1D2NBX2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA-binding protein fusilli</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03904</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ESRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBX2"/>
    <dbReference type="STRING" id="48709.A0A1D2NBX2"/>
    <dbReference type="OMA" id="VQHPSAC"/>
    <dbReference type="OrthoDB" id="431068at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12741">
        <property type="entry name" value="RRM2_Fusilli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050666">
        <property type="entry name" value="ESRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034980">
        <property type="entry name" value="Fusilli_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13976">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="374"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="216"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="754" mass="83764" checksum="5B1CCDBF02F153D9" modified="2016-11-30" version="1">MCDTHDSTMPSNILPDYLGILYIATAGQNGTNLGTDEEEVVLLSLSIVQRDLKKVLASTSLLVQPRGKSSADINENEHSSSSDLLSEECKAELGISENELREKGKPLVDVISELDTLIRRHVEVEEEVIEDETKESRTRSSMSFAFITEGQLPLRQCLHPEACTKDILLPEYYYSFFDLKKEFCACYNQECETTQEMVKFLELKVCKVEDGDESRVTEQTELELEREDECNRNPDDDEEKKSATESNYKAKLPEMTAVVMRLLEDVNTFQKPESIMVKLEPGICSKNESVDGNCVVRARRGGVALCLSPQGRRNGEALIRFESLEHRDMALKRHKHHIANRYIEVYKASGEDFLSVAGGNNNEAQAFLSKGGQVIIRMRGLPYDCTPKQVVEFFDSGENACKVLDGEEGVLFVKRPDGRATGDAFVQFQHEDDASNALAKNRESIGARYIELFRSTTAEVQQPPSNSQLNGPSHILPQHIITSGTRKDCIRLRGLPYEAQVEHILEFLGEHAKNIVYQGVHMVYNAQGKVLVCRANASGEAFIQMDSEQSAYLAAQSKHHRYMHHFKKQRYIEVFQCSGDDMNLVLTGGIPKHNSPSSVSQATAQLLHAHPAGMLSSPLGNVNLSPPSLVLSPHAQALHSMGGLVRLRHGGNPHHHQLNAPQMVLPHGLHMQQSLNPLAQFQNVGLFQHQGQLYQEELFNAGGHRALMGGGGGGGMLKRGWEDAFGNQQVLDYGIPSPKRWVGGLPAHHHGHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC31</accession>
    <name>A0A1D2NC31_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC31"/>
    <dbReference type="STRING" id="48709.A0A1D2NC31"/>
    <dbReference type="OMA" id="GFYFEYL"/>
    <dbReference type="OrthoDB" id="5065855at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="24827" checksum="15301014C52427E8" modified="2016-11-30" version="1">MSHGKVVLDYGDSLIRESEVDILKTNQWLNDAVIGFHFEYLGNQAKSHNDPKLELYGPAVTQLLKLIPSSEELQCILGDGLETIEYAVWPVNDSTETEKGYSGSHWSLLVFSRPDNKFMHFDSYGGSNESAARMLYKKLSPLFSSTSTFHDFEGCCAQANGRDCGLHVIMNAELIVDFIHKSSLSSRPSLWKNGLSTATPKQAESKRKELLELIASLSKHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC52</accession>
    <name>A0A1D2NC52_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Death domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC52"/>
    <dbReference type="STRING" id="48709.A0A1D2NC52"/>
    <dbReference type="OrthoDB" id="1394818at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01670">
        <property type="entry name" value="Death"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016729">
        <property type="entry name" value="FADD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15077:SF12">
        <property type="entry name" value="DEATH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15077">
        <property type="entry name" value="FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00531">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00005">
        <property type="entry name" value="DEATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Death" evidence="2">
        <location>
            <begin position="74"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Death" evidence="2">
        <location>
            <begin position="300"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="41712" checksum="ED9FB12BD0F7B45C" modified="2016-11-30" version="1">MGSNVNIERGPFGKVLVTRHLSPRQKQPIFEFNLQKHGNEADIQPPKSPKESCSNEWSHVALFEFAQNLFIIDGDNWKLFAKEVGMTQQEIRNISWKDAGKASDPFKMVVEHYKGRGGTPEEFVDAMYKCHRSLKVNGSFSPESKKSKSSTGSSGRGSLSSNNVNFDTYGSHDSDTSGTQSRDSGLPHGRKRSHPSTSNNNTTPKASGSGIVSGSMRSSHKTSKRPRFAKPKSAPSQLSFISDADADADLSESDTSDDNAHVPGPSSCLSLDESRLCRNDKTKLENMFLWDISFYLNISNWRALGRSLGLDETVLIDVDNGFKSTSFRECSYQMLLQWRQKFPSKCTYGTLYCALMKEGMNDVAKQMATITRNNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCQ5</accession>
    <name>A0A1D2NCQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative acyl-CoA dehydrogenase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03666</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NCQ5"/>
    <dbReference type="OrthoDB" id="10262177at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF6">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="55"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="178"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="276"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="472"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="595"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="717"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="910"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="1028"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="1134"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1297" mass="143479" checksum="5AB5F1F584A19FF2" modified="2016-11-30" version="1" fragment="single">MATRYAQQRLLNLCLRSKAQVQYQFATAIHSQRNFSVNHPSFQSYSSPLPDSYYNEEQLQMQATVAKIIETDINPFVDEWEAKEAFPAHQVFKKLGDAGLLGIDKSADYGGLGLDFKYLAAVMEELGTIRCGGVPMAILVQMAMTCQALHRFGSDELKKEFLAPSIAGDYVACVGVSAGSDVANTQTKAVRKGDDLIINGQKMWITNSLQADWMCLLANTSDGNKYKNKSLICVPMKSKGITTQKIHKIGNNCSDTGIIFFEDVKVPAKNIIGDEGAGFFYQMLQFQEERMAGAVGSLKGIDTVLSETIDYTRQRKAFGKSILDNQYVYFRLCELASENEHLRALTYKCIDMFVDGQDVTRLASMAKLKAGRLSREVGDTCLQFWGGMGYTREAGVSRFFRDARLLSIGGGADEIMLEIIAKLMNISPAPPKKNAQQRLLKLSKCSYPQRCFSVNSPSFQSYSSPLPDSYYNEEQIQMQATIAKIIETDINPFVDEWEAKEAFPAHQIFKKLGDAGLLGIDKSADYGGLGLDFKYLAAVIEELGTIKCGGIPSAISVHMAMTSQALHKFGSDELKREFLAPSIAGDYVACVGVSAGSDVASTQTKAVRKGDDLIINGQKMWITNSLQADWMCLLANTSDGNKYKNKSLICVPMKSKGIKNCFSNSKISLRILLKAEHFFAGITRQKIHKLGNDSSDTGIIFFEDVRVPAKNIIGEEGAGFLYQMLQFQEERLAVCAGALKPIDLILSETIDYTRQRKAFGKSILDNQYVYFRLCELASENEALRALTYKAIDMFIHGQDVTRLASMAKLKAGRLSREVGDTCLQFWGGMGYTREASVSRFFRDARLLSIGGGADEIMLEIIAKLLNISPASPKKNSNNSINVSAPSNLILSLRKRHNASYSSQLSDSFYNEDQKLLQARVAKFLEEDVMPHVVEWESAEESPTNELVRKLGKEGLLGTRFPKEYGGQGISYKYQAAYLEQMGTVPAAGPVAGVIGHTEICLPALSRFGSDELKREFLVPSLAGQLLACLGVSEPHAGSDVSQIKTTAKQVGDDLIINGQKMWITSGMKADWICLLANTSTKSKHSNKSLICVPLNTEGVHRVKIHKIGWNSSDTAQLFFDNVRVPVKNIIGEEGSGFFYQMLQFQEERLGLVLCNLQALDRCIAETIDYTRSRQVRGKSVLDNQVVYFRLGELATEIESLRAITYRAVDMMVSGEDVTRLASMAKLKLGRLSRSVADSCLQYWGGRGYTRDVFISRFFLDGRLNPIGAGADEIMLEIISKLIGISPSKSMVSYNKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDZ4</accession>
    <name>A0A1D2NDZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Y+L amino acid transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03232</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000073">
        <property type="protein sequence ID" value="ODN03452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2NDZ4"/>
    <dbReference type="OMA" id="IANEMFK"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF528">
        <property type="entry name" value="AMINO ACID TRANSPORTER PROTEIN JHI-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN03452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="573" mass="63202" checksum="D47C137C6C052C58" modified="2016-11-30" version="1">MDKSKRRSSNTSGNDTETIVQKECLLSVSKTCAINKDLFAACNSTSEVSSIAPTISSTTFSGSINSSSKNSLEIKNGTNGPKTKKKVHEFDLFAVVLLVFCAISGSGVLATPQFVYSYTGNAAVSLLIWSGYGIMALLGALCYIELGITFPVGGGEYMYLNEAFGALPAFLYQWGSFIFVPAVNSELGLVASQYLVAPHVDDIHCPSSQRATRLLAVSFILILSYINCVDPKITERFNKGLTICKLGIMGSMIFCGVNFAVNQGLLTNENFAIRPQPDPQVIELREYDVAKIVRAVYQVGYTYHGLSHLYLLVENVENPQRCLPRGVAIAVPLVIIMYLSVNFMYFVTLDKATILSTQAIANEMFKKVFPSENWIILSWVLPTIIAISVVGTISVRILMCSRINLVGARNKQCPKFLSLVDRKHSTPILSIILQALLAILWALFGSVRLNIGLSIYTEGGFTLAVMYGLIYMRITRPLIPRPLKIPLFVPIVYALVLTSLHVSPFFTLDAAALYERFTLMGGAVAVILTGVPVYFILVRRKTNYGWLSRLNNDSTVFLQKTFNLVTEEQFHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE78</accession>
    <name>A0A1D2NE78_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase accessory subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE78"/>
    <dbReference type="STRING" id="48709.A0A1D2NE78"/>
    <dbReference type="OMA" id="VPHIAHD"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03043">
        <property type="entry name" value="QTRT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028592">
        <property type="entry name" value="QTRTD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="45"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="494" mass="55301" checksum="0E8F6A0B390289FB" modified="2016-11-30" version="1">MKKFRVEKTLKTNSGSIRLGHLQLPVSSSGVVEDGDKKRSSERKNDYGTPMFFLHTQTGSIPHITAEVLQLIYPTSTPSISSQTPPVQISLDSTTKFMDALKKFGKGVGKFVGLSDYPIFLTVHDPLYLLRSGHNDKFGIALWSRHGRRPLSPQQYHEAATAFKPSICQVLSDYDVNPKISGTKRLQKSLDRAEEYTSCIIKQQETEPKNEALGLFITVEASWFQMDEGRATKTVLKLLESQHQIEGVVLAGLTDRFPKKDVEVKKNPSGKGSSGERERVDICQALDVDLLEKILQTLPPGLPKYIPGPLRIPEMMDLIAKGVDIFDSSVASRMADDAEVFLLDSVEALLPSISSTVVKLSSSLNEGLPERESNEKNQPSREDEEGAVVSLKNKKYFDDFGPLSSFCVCYTCRKHTRSYIHHLYATDELLGPVLIQIHNLTALDRFFSIMRTLIKECDTPESLQTKLDLIRNLLNNRILRQAEEEEKVAVQAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF55</accession>
    <name>A0A1D2NF55_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Conserved oligomeric Golgi complex subunit 6</fullName>
            <shortName evidence="11">COG complex subunit 6</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Component of oligomeric Golgi complex 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_02836</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Required for normal Golgi function.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Golgi apparatus membrane</location>
            <topology evidence="2 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COG6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000061">
        <property type="protein sequence ID" value="ODN03879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF55"/>
    <dbReference type="STRING" id="48709.A0A1D2NF55"/>
    <dbReference type="OMA" id="HSCLDFF"/>
    <dbReference type="OrthoDB" id="272987at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010490">
        <property type="entry name" value="COG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048369">
        <property type="entry name" value="COG6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048368">
        <property type="entry name" value="COG6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506">
        <property type="entry name" value="COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20653">
        <property type="entry name" value="COG6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06419">
        <property type="entry name" value="COG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01087">
        <property type="entry name" value="COG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric complex COG6 N-terminal" evidence="12">
        <location>
            <begin position="52"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved Oligomeric Golgi complex subunit 6 C-terminal" evidence="13">
        <location>
            <begin position="193"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN03879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="630" mass="71159" checksum="DAC7BE828A667426" modified="2016-11-30" version="1">MDKGRPAEVQQTLQQTVNGVLELRIASDQKLLDGLEELSKVADIDELIIPPKNRKTHRHDLKSLIQRQHVGSYRNFLSEFKEVKDAVGTLHSELGELNRICGGMANNLWVSKQNSRNLIDEISKLESERKKLISERDIAQAYLNAFQLNADDLRVLRGTDNQSGLLSEEFFEVFEKIQKIQANVAVLLKIGHQTTAVEIMDQMGLFQETALEKIYRWAQIHCKNVENPDLSEVLSKSLSYLQIRPMLLKYVLDEYCAHRRSLVVRNFIDALTGVGNIKGIELIGSADPARYIGDMLAWIHQSIPGEKENLMILLKKCNKIDLSEKISNALATIIDGVCRPLNVRMEQTILSGLDCSVMNRIDIRIQFYVDTLEQVLPGSNLLITLRELQTLCHQTFINQLKCQVQAELGEYRPPGPDLTPSSSIEALITVLHEILHDTTDASPQQMNILIQLVVPPLVTQINDVANRLGSPDTGVYLCNCLNQIIQNLEKYQTTEQLRRSLKGQIDMQIDRLSAEQSGWLVAQMGVTHMFTILQEKIDDPLSNVPGMDAASLKIFVNKLDSLIHNPDSVLLPQILHVIDPQTKTMIQKQSFRILVAIYKQVYDAVNEPKNAYPKDLLNLEPDQLEKSLCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGB4</accession>
    <name>A0A1D2NGB4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hydrolethalus syndrome protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02380</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HYLS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGB4"/>
    <dbReference type="OMA" id="LHELIFP"/>
    <dbReference type="OrthoDB" id="6343432at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052319">
        <property type="entry name" value="Centriolar_ciliogenesis_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027918">
        <property type="entry name" value="HYLS1_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34174:SF1">
        <property type="entry name" value="CENTRIOLAR AND CILIOGENESIS-ASSOCIATED PROTEIN HYLS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34174">
        <property type="entry name" value="HYDROLETHALUS SYNDROME PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15311">
        <property type="entry name" value="HYLS1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centriolar and ciliogenesis-associated protein HYLS1 C-terminal" evidence="9">
        <location>
            <begin position="312"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF15311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="366" mass="41642" checksum="D796728712B362C8" modified="2016-11-30" version="1">MPIIITKDEVKEFLEEQGFDVSDENTLRKFVLDLKKLIKFEDMKRRRHRLGHRPEETVLDSTDGRHHATASSRRRDTRNEDDFEDSEEESRTPHTSHQPRSPSVEMLYSNGRERDVIASGSKGNERSSTESYRSSSLEFVVSDEKAPAPLTTRPQNNAKGVAVNNKSAKRLIMKRVTAGKNPNGESVIEESDVDLGPAKRPIGNNFKKKPPLRPQTAPIRSTAPFRKGAADNRQGPRPTSARDKAAKTNAGKPTDVDYANGKQGKCDREPDELFNVLHELIFPSDNLDSQDTLFSDASKPKKLPMPPPHVARDPVALYHWYKRNNWDIYSIPGEDRHMQLRWNVRAKTAQEPCAFRQQPQYVKQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGK6</accession>
    <name>A0A1D2NGK6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02436</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000050">
        <property type="protein sequence ID" value="ODN04235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGK6"/>
    <dbReference type="STRING" id="48709.A0A1D2NGK6"/>
    <dbReference type="OMA" id="KGLYWAR"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990221">
        <property type="term" value="C:L-cysteine desulfurase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000003">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000184">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002806">
        <property type="entry name" value="PRK02948.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010611">
        <property type="entry name" value="PRK14012.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="10">
        <location>
            <begin position="80"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="477" mass="52593" checksum="B890D3F1D1CF3983" modified="2016-11-30" version="1">MAFRIARGAWIKWMNPSVIHHQNLSPVSSKPNSFTCRAVSSESFQNGGKCFRNYSTVINPEQAFEGVTITIDGVEGRPLYLDAQATTSLDPRVLDAMLPYLTSFYGNPHSRTHAYGWESEKAMETARKQVADLIGADPKEIVFTSGATESNNIAIKGVARFYKSKKKHVITTQIEHKCVLDSCRALEAEGFKVTYLPVQQNGIIDLDQFKEAITPETSLVSIMTVNNEIGVKQPVVEIGKICRENKIFFHTDAAQAVGKIPMDVNEMNIDLMSISGHKIYGPKGVGALYARRRPRVRLEPIFSGGGQERGIRSGTVPTPLVVGFGAACAVSQEEMAYDIKRITGLSNRFCNLIDSELTHVIRNGDAVECYPGCVNISFAYIEGESLLMALKDIALSSGSACTSASLEPSYVLRAIGADEDLAHSSIRFGIGRFTTEAEVDYTADKCIRHVKRLREMSPLWEMVQEGVDLKAIKWSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH91</accession>
    <name>A0A1D2NH91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02036</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000039">
        <property type="protein sequence ID" value="ODN04631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH91"/>
    <dbReference type="STRING" id="48709.A0A1D2NH91"/>
    <dbReference type="OMA" id="MIFAYNI"/>
    <dbReference type="OrthoDB" id="8174021at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060857">
        <property type="term" value="P:establishment of glial blood-brain barrier"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035159">
        <property type="term" value="P:regulation of tube length, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019991">
        <property type="term" value="P:septate junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694:SF4">
        <property type="entry name" value="LD42595P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694">
        <property type="entry name" value="PASIFLORA 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="247" mass="27958" checksum="5441FD9026E750E7" modified="2016-11-30" version="1">MHRAPSIGTPSIYSHTTTRSTGLRSSKSVKSLHIPWYKRPMVTNLFGFDIQRLSLFTSIYSIFLSIFTMGISCFDIYCLDEAAPGSTHYGYYIISFDFVYVGNKHVRNALIAIAVFSMMGGMALFVTSIMLLNALRNEYERKMIPWLICMLVFASWRLLAFLFCAVVNDMIFAYNIIMTLFWIVFTIFNYIGWAAVYSLFLELSDLTKLEDLAHLRMGTMTSLATQSMAGSRPTTPHSTTSTVPLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHA4</accession>
    <name>A0A1D2NHA4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000039">
        <property type="protein sequence ID" value="ODN04643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHA4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18546" checksum="A62A318C7BF66A83" modified="2016-11-30" version="1">MSRNNLNQPSSPGRSNSLTPPGLFSRPRGENTGSARQSVSNVLEFSLSDSVAQDNPSSYSVRRYNHFANFRRHLNIPVTPPAEMDEHAEGAVGHSPSVSPDTISPSPRYSSLKPEEKKKDKKKDKKKGNKNKNENKEKKDIKKPPEDSDEEELPPTFRWVHIEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHI1</accession>
    <name>A0A1D2NHI1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="37">Trifunctional enzyme subunit alpha, mitochondrial</fullName>
            <ecNumber evidence="36">1.1.1.211</ecNumber>
            <ecNumber evidence="6">4.2.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="38">Monolysocardiolipin acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="39">TP-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="44" type="ORF">Ocin01_02006</name>
    </gene>
    <organism evidence="44 45">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="44 45" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="44">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="33">
            <text>(3S)-3-hydroxydodecanoyl-CoA + NAD(+) = 3-oxododecanoyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31179"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62558"/>
            <dbReference type="ChEBI" id="CHEBI:62615"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="33">
            <dbReference type="Rhea" id="RHEA:31180"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="30">
            <text>(3S)-3-hydroxydodecanoyl-CoA = (2E)-dodecenoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:31075"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57330"/>
            <dbReference type="ChEBI" id="CHEBI:62558"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="30">
            <dbReference type="Rhea" id="RHEA:31077"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>(3S)-hydroxydecanoyl-CoA + NAD(+) = 3-oxodecanoyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31187"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62548"/>
            <dbReference type="ChEBI" id="CHEBI:62616"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:31188"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>(3S)-hydroxyhexadecanoyl-CoA + NAD(+) = 3-oxohexadecanoyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31159"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57349"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62613"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:31160"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(3S)-hydroxyhexadecanoyl-CoA = (2E)-hexadecenoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:31163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:61526"/>
            <dbReference type="ChEBI" id="CHEBI:62613"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:31165"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>(3S)-hydroxyoctanoyl-CoA + NAD(+) = 3-oxooctanoyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31195"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62617"/>
            <dbReference type="ChEBI" id="CHEBI:62619"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="29">
            <dbReference type="Rhea" id="RHEA:31196"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>(3S)-hydroxyoctanoyl-CoA = (2E)-octenoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:31199"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:62242"/>
            <dbReference type="ChEBI" id="CHEBI:62617"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="28">
            <dbReference type="Rhea" id="RHEA:31201"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="31">
            <text>(3S)-hydroxytetradecanoyl-CoA + NAD(+) = 3-oxotetradecanoyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:62543"/>
            <dbReference type="ChEBI" id="CHEBI:62614"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="31">
            <dbReference type="Rhea" id="RHEA:31168"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="32">
            <text>1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:43676"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:83580"/>
            <dbReference type="ChEBI" id="CHEBI:83582"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="32">
            <dbReference type="Rhea" id="RHEA:43677"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:43672"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57383"/>
            <dbReference type="ChEBI" id="CHEBI:83580"/>
            <dbReference type="ChEBI" id="CHEBI:83581"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:43673"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="34">
            <text>1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:43680"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:83580"/>
            <dbReference type="ChEBI" id="CHEBI:83583"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="34">
            <dbReference type="Rhea" id="RHEA:43681"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:16105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.17"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="21">
            <dbReference type="Rhea" id="RHEA:16107"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:20724"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58521"/>
            <dbReference type="ChEBI" id="CHEBI:137480"/>
            <dbReference type="EC" id="4.2.1.17"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="27">
            <dbReference type="Rhea" id="RHEA:20726"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD(+) = a long-chain 3-oxo-fatty acyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:52656"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:136757"/>
            <dbReference type="ChEBI" id="CHEBI:136758"/>
            <dbReference type="EC" id="1.1.1.211"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:52657"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="35">Heterotetramer of 2 alpha/HADHA and 2 beta/HADHB subunits; forms the mitochondrial trifunctional enzyme. Also purified as higher order heterooligomers including a 4 alpha/HADHA and 4 beta/HADHB heterooligomer which physiological significance remains unclear. The mitochondrial trifunctional enzyme interacts with MTLN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="44">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.211" evidence="36"/>
    <dbReference type="EC" id="4.2.1.17" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHI1"/>
    <dbReference type="STRING" id="48709.A0A1D2NHI1"/>
    <dbReference type="OMA" id="ESTTIRW"/>
    <dbReference type="OrthoDB" id="10004768at2759"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016507">
        <property type="term" value="C:mitochondrial fatty acid beta-oxidation multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016509">
        <property type="term" value="F:long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000011">
        <property type="entry name" value="Fatty acid oxidation complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000009">
        <property type="entry name" value="Fatty oxidation complex, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.50:FF:000002">
        <property type="entry name" value="Trifunctional enzyme subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012803">
        <property type="entry name" value="Fa_ox_alpha_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050136">
        <property type="entry name" value="FA_oxidation_alpha_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02441">
        <property type="entry name" value="fa_ox_alpha_mit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43612">
        <property type="entry name" value="TRIFUNCTIONAL ENZYME SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43612:SF3">
        <property type="entry name" value="TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0007">Acetylation</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="19" id="KW-0456">Lyase</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="20" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="45" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="43">
        <location>
            <begin position="338"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="42">
        <location>
            <begin position="518"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="active site" description="For hydroxyacyl-coenzyme A dehydrogenase activity" evidence="40">
        <location>
            <position position="484"/>
        </location>
    </feature>
    <feature type="site" description="Important for long-chain enoyl-CoA hydratase activity" evidence="41">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="site" description="Important for long-chain enoyl-CoA hydratase activity" evidence="41">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="site" description="Important for hydroxyacyl-coenzyme A dehydrogenase activity" evidence="41">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00035854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00050222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00050446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00051215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00051877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00052224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00052711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00052834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00052860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="ARBA" id="ARBA00052945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="ARBA" id="ARBA00052989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="35">
        <source>
            <dbReference type="ARBA" id="ARBA00062153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="36">
        <source>
            <dbReference type="ARBA" id="ARBA00066806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="37">
        <source>
            <dbReference type="ARBA" id="ARBA00068347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="38">
        <source>
            <dbReference type="ARBA" id="ARBA00077617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="39">
        <source>
            <dbReference type="ARBA" id="ARBA00083277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="40">
        <source>
            <dbReference type="PIRSR" id="PIRSR612803-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="41">
        <source>
            <dbReference type="PIRSR" id="PIRSR612803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="42">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="43">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="44">
        <source>
            <dbReference type="EMBL" id="ODN04707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="45">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="741" mass="79899" checksum="AFCC85BC3766CD67" modified="2016-11-30" version="1">MSLYLSRSAVMAGNHVKVEIKKNVAVVKLDSPGRVNVLNQPVMEEIIQALKDIQSNTAVEAVVVISAKPGCFIAGADISMLEKCKTVEEASSKSRDGQRVLADIEASKKPVVAAIYGSCLGGGLEAAMACHYRIAVGDKKTGLGLPEVMLGLLPGAGGTQRLPKLAGLPNSLDMMLTGKTLKSDKAKKFGIVDQIIKPLGPGTDSAQNRTMQYLEEIAIKTAQGLADGTVKSSKKKSGMDKVMDFALKFQFVKNKVFEKAKGQVMKQTKGVYPAPLKILEVVRTGLDKGPAAGYEAEANGFGHLAMTPESKGLISLFHGQTECKKNAFGKPQRPAKNLAVLGAGLMGAGIAQVSIDKGYSCILKDATEQGLVRGHNQISKNFETAVKRKRHSNADVEKFFSNLSLQVDYKNFNKLDMVIEAVFEDINLKHKVIKEVEQHIPEHCVFATNTSALQITKIAAASKRPDKVIGMHYFSPVDKMQLLEVITTDKTSQDTIASVVDVGLKQGKVVIVVKDGPGFYTTRALGVFAAEVMRLLLEGIDPKDMDKMTTELGFPVGACTLIDEVGCDVASHIAADFSNVFGERYTGGIPMTLMSDFVKDGNLGRKSGKGFFIYEEGQKGSKPVNPSASAILTTNKIQPKGSLEKEDCQIRMISRFCNEAVMCLEEGILRNPVRLEGDIGAVFGLGFPPFTGGPFHYIDRYGADKLVAKMRGYEQAYGSSFTPCAMLLDAAKGGKKFFPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI91</accession>
    <name>A0A1D2NI91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">pH-response regulator protein palF/RIM8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI91"/>
    <dbReference type="STRING" id="48709.A0A1D2NI91"/>
    <dbReference type="OMA" id="CHEIAMA"/>
    <dbReference type="OrthoDB" id="8251650at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="204"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="435" mass="48886" checksum="9367ADABE608EBE3" modified="2016-11-30" version="1">MAFAILWYARSKLGSKVGSFGCNFKVQIVVDSDVIKPCKKITGSVIIETQRPIKHQGILIQFEGACTLKYPTKSEGYTTNQHGREVILEGAGWKSAEAYFRSPIQHILKSKSESAHVINPGSVTYPFELDIPENPHLPAPFRNELGCLVYRLVVYMAEPIRLQIHVEIGQRIVKFNGHYNLFNDEAAMTPVSVEKSLKTSVFARKKLLDLLLLVEKSGFLPGEIVTFSLSFKNLQCLPLQISVQLMQHLKYNATNRRESIKRKVAILAKLERMYTNHMPECTWMDSLRIPEDQVPSFTCHYMYNVAYCIQFKVKVLAEMKDFGSYVLKGEAPLYIGTTRSTVEHLRIVANSDVPREVTRRSSANSIGSSFSIATTTSTLPPAYSQLSSRIPSWETLPPSYDELELDDPDEISFDGLTLASATQFDTGSPNEKSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIL3</accession>
    <name>A0A1D2NIL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIL3"/>
    <dbReference type="STRING" id="48709.A0A1D2NIL3"/>
    <dbReference type="OrthoDB" id="121932at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032072">
        <property type="entry name" value="DUF4807"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36693">
        <property type="entry name" value="GH02722P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36693:SF1">
        <property type="entry name" value="GH02722P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16065">
        <property type="entry name" value="DUF4807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="44476" checksum="8AC5A0ACB86D8F7C" modified="2016-11-30" version="1">MNLIENANVFCISLKGVVEGHQFLSLVTCRPTNSPKRTRTSSLPSYLEVYDESPSSDRKYEKCCRLQKSARCFSEDSVKKDTFKTVCTKCIYNMVKKDRLVPKTKLARSRKFDLIVPKKYKVISSKRKPVPKGSEDLSCKGGMHKSLVNHLKKPFGIECSATTLQMDGYMLSYFISEIKRSQTFRTSFIRRCTQQPISSLSNQGSQKLLVFVALMKEPDCEVLDLLGNKMVNSNILYRRSLEHALSWLSTLGGAFSALGDLSSSWADKAGHVSLTQLRIAFKLDDPGIKSRCRIYAAISLLQRGYLKSCRDIVRKEYQYAVSLPEDSDPRLRRMCLGVWAKLQYHWKLVPLSDRKSIEEGLQEIRNNVRYRNVYNLEEGRRIASADDVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ59</accession>
    <name>A0A1D2NJ59_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vitamin-K-epoxide reductase (warfarin-sensitive)</fullName>
            <ecNumber evidence="3">1.17.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_01403</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.4" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ59"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ59"/>
    <dbReference type="OMA" id="YVINFAL"/>
    <dbReference type="OrthoDB" id="17010at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047057">
        <property type="term" value="F:vitamin-K-epoxide reductase (warfarin-sensitive) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042373">
        <property type="term" value="P:vitamin K metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12917">
        <property type="entry name" value="VKOR_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="entry name" value="VKOR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042406">
        <property type="entry name" value="VKORC1/VKORC1L1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14519:SF8">
        <property type="entry name" value="VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14519">
        <property type="entry name" value="VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00756">
        <property type="entry name" value="VKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Vitamin K epoxide reductase" evidence="13">
        <location>
            <begin position="11"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN05294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="21003" checksum="6C745DA8B0E9577E" modified="2016-11-30" version="1">MMSLADCRRRVEKLRKYVGLLCLFGTLLSAYTVYVEINLEKDPKYTALCDISAKISCTAVFGSEWGKGFGLVNKIVSENSTLNQPNGVYGVVSYPLYALLSRFNFLLLAKATVFMGTVGLVLSGYLAYILIYVLDDICVICFGIYIINVLLLLVSIWYYRTLRTLRNYTDQQGSTKEPVLGISKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKQ9</accession>
    <name>A0A1D2NKQ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000015">
        <property type="protein sequence ID" value="ODN05834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKQ9"/>
    <dbReference type="STRING" id="48709.A0A1D2NKQ9"/>
    <dbReference type="OMA" id="HDDGINM"/>
    <dbReference type="OrthoDB" id="6365338at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="70" mass="7483" checksum="DD917B60A1A5760C" modified="2016-11-30" version="1">MSSVFVNDGVDSTSESTYSIFQSLQSGPFSPSSPGEPYFDATIPRNVTALVGKTAYLSCRVKNLGNRTVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMA3</accession>
    <name>A0A1D2NMA3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMA3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11862" checksum="CA289A96058426A6" modified="2016-11-30" version="1">MTRIEHFVERRIKVIHPGYFPTIPVLFPESRRDMGWSDCRKNMFYAYIGISFLFTWTAMFHLSIRQQPRGCSFGEMTCKAALGCSRVGLALCKKLKYNNCEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMG5</accession>
    <name>A0A1D2NMG5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ascorbate ferrireductase (transmembrane)</fullName>
            <ecNumber evidence="6">7.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_00312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.3" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMG5"/>
    <dbReference type="STRING" id="48709.A0A1D2NMG5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140571">
        <property type="term" value="F:transmembrane ascorbate ferrireductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF24">
        <property type="entry name" value="DOMON RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="532"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="562"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="600"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="635"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="668"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="725"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN06409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="791" mass="88846" checksum="F52A92F70F8F4C35" modified="2016-11-30" version="1">MRASAPSPQGPPLPPRTTLPFYEKFPEAKPCYEPSPATPPSHSAGNNPNWAILEHLVRHKAQSFQPYDDLPYVYPYIYGSGPASPIDRSIHLNYGPEVDIISPPLPRPNAPNPYFVEVTGISFKGELLHNFLHFRIFANMSVALGKGQVERTEFLHRTEDVETPNYATGKISALVIMVKDQNGWPVGDFSTPVPCLRTCSKYSHDVYYGDERNAVPCSYTPPHASSHPGMFVFDVDPGRYCTSDLPETKGGAAVPASTDPDPRMNPQTARLEGVREVHATWSFGHNTCNFVQRLYIQTLIFEDVETVYPGWFDPKPNDINYGPPEPGKPPKMFPETKASFLFGWTAQYNILKPTRSSLGAPDYVNLKYLRERDARVHEVDCHVPLFDAVKTVPSAFRKFVVPAHETLHDPVLTAIEQAEMAVPTRSGYNAALWKIFKESKDASADNAVRYFGQNTRTTEKCKTFPSTLIVEDNVKKILGSANPPSAKVFFEHKKQDGIRCPCPALASTLPPENRTADPARVHGRLIHASHMAIAYMLLTPIGCFVARYYKETFVSIFCFQEYWWFMWHVVFLIAACLFNIGAITSIARKKQLDLKYNDNLIFHVVFGALSIFVFYMEIITGFFRVADSKKRMRQIFMHWLIGTMNNACAVMSMFAMAFVNQSGFSCNVAYATIFWLFFVITCYSLMEVNMRKTDRSLHLVPRRTYLPPPVKRLFTKEPPGRNFRLGMLAVFIFGLIGIQFLVSYYIWDTVNTGGASCQEEWEAYRPKVISNYGGTGGGGGGGGGAGGYYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0D5</accession>
    <name>A0A1D2M0D5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01009272">
        <property type="protein sequence ID" value="ODM59387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0D5"/>
    <dbReference type="OrthoDB" id="2142040at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31649">
        <property type="entry name" value="AGAP009604-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31649:SF1">
        <property type="entry name" value="FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00696">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM59387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17575" checksum="532AFA6919BAA6AB" modified="2016-11-30" version="1" fragment="single">NLTSPPSYGITWALGNSVNPSQLEPAGEDKNGILYVARTEVNGEWVPGKGYYRGRTFYASVAFMGKEIESADCSVLLRGGTKWIAQQKNREIPNDAVFAGNDPRTHEKTYICRGFAIEEGRTWLIVGKVLENYKIACRLPFNGETSAFSFEVLVYYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0G4</accession>
    <name>A0A1D2M0G4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01009039">
        <property type="protein sequence ID" value="ODM59404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0G4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM59404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="476" mass="54786" checksum="E41875503D5D7C4B" modified="2016-11-30" version="1" fragment="single">DSDEIVKLAHEDAVLRYISAARCSTIFGVLIHKQLNFRVSSVQAGSLKKRKKRNLGHVTGLGAVPYNELRDQFDGRTLFTSSATSERHPVSYRNASDTRISMSSLLGCEKTRSTTRVTRDPNFHIHQKQADTTLLDKVEVVSGSRASSSDHSSMPHLPSTNERPVLLDKSTMNRLRLIVFIGMITGALPWFWDNKTLRLRKFGRLLHKFWWVQWTFITIQTVFLFGIQIWMFYGSLQGEIRSYRGVFISLMTIYWYIFALSYRAIVYLYQDEMRQYINTMLAFNQSYVEQYLIHTEGYKQGGMVVINLSIPAVCLQIFTSLALFLIFHAKPWYLYSHVHPKPWYWLIPGSIQDVIVTGSDITIYMLMSWLIVSHTNSVNFWLKEIHNNNDSDYTTDELRHPKKAIETFRCLQILTTLFNECMSTLGMPLLKLTIILGLVICGFVIVRSMNHLFVDEMPSILLYPIGIINCAANGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1P9</accession>
    <name>A0A1D2M1P9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19831</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006982">
        <property type="protein sequence ID" value="ODM86851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1P9"/>
    <dbReference type="STRING" id="48709.A0A1D2M1P9"/>
    <dbReference type="OMA" id="LEMIFID"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="2"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="324"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM86851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="482" mass="53557" checksum="83B7C47668605FA4" modified="2016-11-30" version="1">MLGGSSATNFMIYMRGNPKDFDRWANISGDSRWRYSNVKKYFKKMENYHGIYKNDTKWHGKNGPLTVESVNFAPGLKEVFEAVNEWGYKILDLNTEQEEGFSTLDATQNRGRRRASSYSAYIEPILGRPNMRILRYSHVTKIHFDSELKARGVYFARNGTTFYVPVKKEVIVSGGTINSAQLLMLSGIGPSKHLKSVGIQPLVDLPVGRNLADHSMTVVGPFILNRAASLMLPRDVSLKSLVDFQVYGQGPLTSPMGLMGIGVTSTSSSPGWPNLLHVIDSMGIFDGFGPIIDGMFGSGSHYTNLVQNFSGLDAHSVLLTLGKPKSRGFIELRDSNPFSKPIIDPQYYSDEKNQDMLDMIEGYELIVNLYEKSKALGRKLGARLIEVQSCAKYGVKTRAYYECAIRTPILHLFHPVETCHMGKIGDPNAVVDSQLRVIGTKGLRVIDASVMPEITNANTNAPTIMIAGSRLRFNKTKLQPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2B7</accession>
    <name>A0A1D2M2B7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_19599</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006205">
        <property type="protein sequence ID" value="ODM87082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2B7"/>
    <dbReference type="STRING" id="48709.A0A1D2M2B7"/>
    <dbReference type="OMA" id="RCHECIF"/>
    <dbReference type="OrthoDB" id="6572853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050636">
        <property type="entry name" value="C2H2-ZF_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772:SF13">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM87082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="274" mass="31900" checksum="A8FBB9857D825379" modified="2016-11-30" version="1">MFKGSPQTRTQPELRNLFQVILYFIQANSTYRSHIGEKPFECSHCGKGFSRNGRKKTHFKYKHTNVDKSHKCDVVAKFFFNKSYLKIHAHVHTGESHSHVQLVESICCESKMRRHFRDVHAGLLTVRRSTNVEICFKSFFGKFECQLHVHYHTEKKPFKCTICNKRYATAHTLKVHKLSVHAISCNLCGKCFAQHHSLTSHLNRHLGEKTQKCGLCEKSKELRIHTKYHVGDRCHECIFCRKDLLLTLSLQSISLFIISMKRLTIVNAVIEIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3R8</accession>
    <name>A0A1D2M3R8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL50</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">39S ribosomal protein L50, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19098</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005020">
        <property type="protein sequence ID" value="ODM87584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3R8"/>
    <dbReference type="STRING" id="48709.A0A1D2M3R8"/>
    <dbReference type="OMA" id="HIQYEYV"/>
    <dbReference type="OrthoDB" id="9939609at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018305">
        <property type="entry name" value="Ribosomal_m50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31542">
        <property type="entry name" value="39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31542:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10501">
        <property type="entry name" value="Ribosomal_L50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="261" mass="29655" checksum="ADF54CC8B4284A3C" modified="2016-11-30" version="1">MLRKAVVWPPQVKEVVASRCAAAEGNWNLNVSSVYLPQYQSVRARSKHETHKHLTFSKMGKNFTRRPLIDQKLLKQGAPVSATLDLGDMTKVRKFEFDVAALNTRGFLRYQKAYAPPTNAKETVLQLCESVFSKESAKGEGYLMNAKITDSRLKYDLLSKLYNEFQHAVPNSMLHMMETVGDVVQFYCTPIEIHTPYEELIRNKANLPPNLHVQKDPIRFQPGTDTDIFDGQTAFNKSSTIVTGLRAKKKFPGFQAKMTWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3S3</accession>
    <name>A0A1D2M3S3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004940">
        <property type="protein sequence ID" value="ODM87627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3S3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="64" mass="6979" checksum="A7D02FADF77F289D" modified="2016-11-30" version="1">MEVQETVLTSHSLLIILLICHIIFSVCWTLYCITGAEKQEMNYGGPVVGIHVTFLPASLSSSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M439</accession>
    <name>A0A1D2M439_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004777">
        <property type="protein sequence ID" value="ODM87739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M439"/>
    <dbReference type="OrthoDB" id="7305308at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="81" mass="9172" checksum="1918580EC4B3B405" modified="2016-11-30" version="1">MSIHRVYTDSRLQTKCTLHIRLISHHPAMVSVSPNHVIREALTDPEILSCFQVIKELRPHVPPQRKSSTASNSNNQKTTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4L2</accession>
    <name>A0A1D2M4L2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prolyl endopeptidase</fullName>
            <ecNumber evidence="4">3.4.21.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Post-proline cleaving enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_18818</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Pro-|-Xaa &gt;&gt; Ala-|-Xaa in oligopeptides.</text>
            <dbReference type="EC" id="3.4.21.26"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.26" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01004520">
        <property type="protein sequence ID" value="ODM87864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="248387at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070012">
        <property type="term" value="F:oligopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.120:FF:000001">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000005">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000275">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051167">
        <property type="entry name" value="Prolyl_oligopep/macrocyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881:SF2">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="13">
        <location>
            <begin position="7"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="13">
        <location>
            <begin position="674"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="12">
        <location>
            <begin position="1163"/>
            <end position="1346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM87864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1375" mass="156053" checksum="FF0E277EE7DF39E0" modified="2016-11-30" version="1">MTRINYPDIRRDESVVDEYHGTKIADPYRWLEDPDSDEVQKFVEAQNNITIPFLEECKPREAIKTRLTELWNYAKYGCPFRRGDRYFYFKNTGLQNQSVLYMQRSLEEDGEVFLDPNTLSEDGTVAISTYAFSKNGEVFAYGLSGSGSDWITIHFKNVLTGENYPETLQKVKFTSLSWTHDNVGVFYGRYSDQEGKTDGSETTSNENQKLYYHRLGTEQSEDVLVVDFPENPKWRIGAEVSDCGNYLIVSPQQDCRDNLVFFADLSEPLKSGLKTKLTLTPVVTKFEADYIYVTNTGHLMYFRTSRDAPNYRIATIDFSKPISETSWQTVVPEHSKDVLDWTACVNGDVLVTCYIQDVKNTLQIRKLEDGSLIKDFTLEVGTIMGYSGRKEDSELFFQFASFLTPAKILYVDLKSESLEPKVVREVTLKGFNPSDFETTQVFYDSKDGTKIPMFIVHRKDLVKNGNNPCLLYGYGGFNISVQPTFSVTRIVLMQHMVVYLLLQIFVEEEYGESWHNGGRLLNKQNGFDDFQAAAQYLIDNQYTSSKKLAIQGASNGGLLVGACVNQRPDLFGAAIAQVGCSDYGCSDEKEHFDNLLKISPIHNVKLPEDSNGQYPSVLLLTADHDDRVVPLHSYKFIAEIQTKVGKSSQQENPLLIRIETKAGHGAGKPTAKIAIDHYHWLENSNAPNVLQFESAQNDLTQNFLKSCPQLNEVKSMLLSVSNRCHVSCPTEDVTTGRFYFFMNSPDENCDSIYVKEGLKGKPRLHLSPKDIPETNGKAVFRMYSLSWHGETLAYAYGTLTSTMQKIRFRETKTGKDYSEVLTNVFYSDISWTHDNKGIIYSTYLNSKKNEVGHLAVVFHRLGTKQIDDLIFVEFLDSPYLTLQAQISDCGELLFVYANEKGINQHCNFLYGDLKGVAKNNYETTPYLFHLLEGNGLEIQFITRIHGATYFRTNCRAPKFRIVRTYLLKGTKLTKGFWETIISEHSTRLLDWAVCVNKHYLLVCYVEEAAHKLQLHKLQDGSLLHKYSLPLGTITEYSGGSQNSRFFFTFSSFLIPDCIRYIQVPKHSPKRFRNALHLMFKANAKKMKYFNRDLIKIVDSSDCCLKQRFCVSPTDGADIPIFLIHKKGLKLNKQSPCIMYGQGCFGVQIMPSFCVAKLAFVKCFNGLIAIVGTRGGGEYGEEWYRGGTCQNKQQTYNDFIAASEYLIKLGYTSPSKLIIEGQQFGGNLAAACLVQRPDLYGAVIIHNGLLDLLRYHLLQESQSYLSEFGDPNIFANFENLRKISPLHNVLNENTFLKIPAVMTIVDKENGLAHPSNSYKFIAELQFNLASKSTKKNPFLLWTHRHASSGQGEHSNNYPATQYQLIFPNTNPLFAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4R4</accession>
    <name>A0A1D2M4R4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">BET1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Golgi vesicular membrane-trafficking protein p18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_18713</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with SNARE complex members GOSR2, SEC22B and STX5. Interacts with LMAN1/ERGIC53. Interacts with STX17.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endomembrane system</location>
            <topology evidence="14">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Golgi apparatus</location>
            <location evidence="12">cis-Golgi network membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the BET1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004309">
        <property type="protein sequence ID" value="ODM87968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4R4"/>
    <dbReference type="STRING" id="48709.A0A1D2M4R4"/>
    <dbReference type="OMA" id="GHRNYMC"/>
    <dbReference type="OrthoDB" id="261831at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000026">
        <property type="entry name" value="BET1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="20">
        <location>
            <begin position="20"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00054011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00063965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00071590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00077825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM87968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="113" mass="12974" checksum="FB39A4B511F55CE2" modified="2016-11-30" version="1">MRRAHANQYPPDFMQGMQDPALETENDRMTDELKGKIQSLKSLTIEIGSEVRGQNQYLRDMDDEFDNAGGFLGKAMGRVKKLANGSHNHVVLYLLLFSFCVFLFLWLLIRFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M548</accession>
    <name>A0A1D2M548_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase/endoribonuclease ire-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004101">
        <property type="protein sequence ID" value="ODM88110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M548"/>
    <dbReference type="STRING" id="48709.A0A1D2M548"/>
    <dbReference type="OrthoDB" id="5794026at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="61"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="23112" checksum="345DE312788D7566" modified="2016-11-30" version="1">MGLVTNRSNQVFQLYSILQQRVNAFDALLEGLQETNQTGALDILTFGMEQNCCSFTLTLSYDRNTVLGLGGYGTVVYKGKIGERDVAIKKVHLSMFGGDQALHEVTVLKDVDAHENVNKWVENNAQNIRLTETSELSCMEVLRQITTGLEWLHSEKIVHRDIKPENVLLLLQMKRAKLSDFGLSRRILDGSSFVVTSNVGGTHGLEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M574</accession>
    <name>A0A1D2M574_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_18569</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004099">
        <property type="protein sequence ID" value="ODM88113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M574"/>
    <dbReference type="STRING" id="48709.A0A1D2M574"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001480">
        <property type="entry name" value="Si:cabz01071911.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000744">
        <property type="entry name" value="zinc finger E-box-binding homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000417">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF23">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="358"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="559" mass="64899" checksum="9AB5103EB077AE38" modified="2016-11-30" version="1">MITCRYLHANCSVCKRRFISSDELKKHTQIHIDPVNKFSCLFCEKVLSTEAGLNSNISRHINEKPDDCKYCEMSSHVSRVHEKLRKPKPIDCVMCGTICLGSSHLRSHLLRHTREKPFSCLVCGESLGTSAALRIHKLSWYTKLTPEDLERLFKCGVCDKVCKSYSSFQTHKKKHKPKRLYQCDQCPKKYASSNALQEHKSKHNGEFHYICQVCGKGFHYSGNLGRHVRTHTGEKPFRCKVCKKCFSARDSLKSHEQIHVDVGNKFWCLFCDKNLRSRISLNGHILRHIKEKPVNCKFCELSFASTDNLKSHGKKFHEAYFKKPGQLQRHMCIMCEKSFPTQSQLIRHLQRHTRERPSPCTICQQSFRTNSELAMHIRIKHTKCKPFGCEICGKRFAHKSVLTQHIQRHLGEKTIKCSKCHKGFITNGDFVKHSWTHNKSLSQNVCIFCEKGFYIRNETNFNRHIRQHTREKVYICDTCGQEYACASGLQVHQQIHSGIKPFVCVFCGEAFFTFNRKSNNSLEQHLRNHIGEESFACDDCPGCFVSWNKLLAHRRMMHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5Y8</accession>
    <name>A0A1D2M5Y8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003655">
        <property type="protein sequence ID" value="ODM88388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5Y8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903519" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9552" checksum="34BE65288067B886" modified="2016-11-30" version="1">MLLKLLPILVLLGVVAMSNGDADSCVGIFTGEVNCLADKGKFVYFEGENEACLPIVSFKSDTGEPSVPCMGQKKFDTEKECHDTCFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M637</accession>
    <name>A0A1D2M637_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003605">
        <property type="protein sequence ID" value="ODM88439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M637"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="13709" checksum="27341210EEB90C0C" modified="2016-11-30" version="1">MQENQGTVMATKANNVDGYEVPFQKDVGKLLGKFGLAWPDLLLIITLLETAWWITFGFLDGADVTLRTTFDYNDQLYPVYMLVKRTVCLARLAGVIWCVWYSCIIQVIRLHFESELTLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M693</accession>
    <name>A0A1D2M693_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003538">
        <property type="protein sequence ID" value="ODM88483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M693"/>
    <dbReference type="OrthoDB" id="10023262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="424" mass="46096" checksum="6AF588773F842C9D" modified="2016-11-30" version="1">MTVMEQLTNSVTKWPKCVKTYNPNWEKDPILKTWINRHPSDNGKVLCRFCNSIIRAHKNDLIEHTRTRKHERNFKQQAPPDAFNKFLEDLQGLKKTPAMAKRFANSKQPSPTSLPLQEDSVTQLKYEPGTACFMESGDETNGSTGSRTPDENVICIPSLSLNCDIGEPEQSIMEEVLCDDDLWSHEGEEFNISAESPSDLVSVILEEQQSPQSNSSTPCLVPSPTTSIIASVSPNDSRTLQTIEVLAHGIHSLEGVNFTLVGGATLASPQLVSASNSSNFITTTQSSETIPFVSVTTQDIPVALETVNGSIALDAKRAGPSLKLKDVISAIESGVFSLPELCSLAKMALNKVEENVSGKEPSKISTIGRSSNCNGTIQEIPVSLAFACGDSMESFEHATIKTERSDKKRRLELITTASSAGTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6F3</accession>
    <name>A0A1D2M6F3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_18121</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003426">
        <property type="protein sequence ID" value="ODM88557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6F3"/>
    <dbReference type="STRING" id="48709.A0A1D2M6F3"/>
    <dbReference type="OrthoDB" id="9419637at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000103">
        <property type="entry name" value="Histone H2A type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="12"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="10634" checksum="F5A06C331807EEED" modified="2016-11-30" version="1">MSGRGKGGKVKGKAKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNALVTTRRRVSFPVISNSPSAVLLPKKTEKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6J2</accession>
    <name>A0A1D2M6J2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003405">
        <property type="protein sequence ID" value="ODM88589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6J2"/>
    <dbReference type="STRING" id="48709.A0A1D2M6J2"/>
    <dbReference type="OrthoDB" id="514823at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="23473" checksum="0AAF1C06029529FD" modified="2016-11-30" version="1">MFATQATKPKAKVVPVVESKNKKSSSTTSSNKPKDSSKVKSEPKATNSDTRKRKRIRDVLSSSESEEEKDKDSDVEESLPESPLPKRRIQIESDSEDDEDIKKEPSKPEEPVKTIDESKSTGTGRRRVAKMVSKSFLDKDGFLVTTKEQVMVSEDEASDTEKPKNGNQNGKSLEKPDEQKRAKPANGLALKKSPVGTGKAKQSSLMSFFQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M836</accession>
    <name>A0A1D2M836_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized transposon-derived protein F54H12.3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002933">
        <property type="protein sequence ID" value="ODM89074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M836"/>
    <dbReference type="STRING" id="48709.A0A1D2M836"/>
    <dbReference type="OrthoDB" id="6343797at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585:SF1">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585">
        <property type="entry name" value="INTEGRASE CORE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="33"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="947" mass="108491" checksum="8025691A86BA1528" modified="2016-11-30" version="1" fragment="single">GSFAGLRKFYETRKPPASLKDVKQELLKLESYYSFFPARRRFKRRKVVVHFANFQFCSDLIDLNRYLKFNKPYRYIIVFLDCFSRKLYAYPLSSKQPKNIVAAFKKLFRQLKKPFFYLQTDLGTEYTSKETQNFLKKKNIIWFNTYSEIKASLCERVIATLMQKFQRMFTHRKSLNWKSSLTAMVSSYNTQIHRSLKLSPNDASKEENNDIVWKALYEKYIAEPVEKPVYFPEQRIRISLNKKTFDKGYSRRFSNEVFEIARVLDTQPPTYIIKDDKGEEEHSTKTNSYQREMDEINSLYITLTSSTNAETSPSNFINNIATPIKLDEGVHEIGLTEITYEPCNSIFGFEEGDNIILVQSDYESKAIFSIVKEQSLASDITLFNRNCKEGSIPIEIQQMSIKRQIYYRIVIKYAGDIGVKLSENFRTILGFENEIYHSQSNLGEKPMNLPVYNNLPSGTLISFEVVDLPQITRLVLDEPTEYTPEGFASMKPYGLLGETNAHMMAFPSKSTKRVERKKRRPKKKMVGNGKVKKKGKATKVARTKLDFVGYGHSKKRSCVKKKKVKTKHVESPGEEDVSIRSSFFQKCFPIGNLEDVEQPIEFTASGSPGVYYDLKNSFLYTTLKVTKNDGTNIADANDVAVANFIGSTLIKKLDLFINQELISSSNNYNYVSYLKSLLSYPINYKNNELRESQYYFDDSPNTSVVANSSYKKRKDIIKFSKLIEVVTPILDDLFLVNKLFHPGFNIKLKIERASSEFCLVSSIDTVKYGLTQIDVQVDGQSNDSSLKIGETEHLLAYHMLMDTLGPGFSSCGINPANYMNGNLIFGFRLSRNELSKDQDGKLTIILNFGSGCTENVTALILGQLRSSVVLSANELLSALAYILADRKISSYGVIPPSKIRMFILAPCPKVYIVNTHEFPGKHWINFHKYSIDIPLNRLHLYHLQSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M948</accession>
    <name>A0A1D2M948_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxygen-dependent choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_17182</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002590">
        <property type="protein sequence ID" value="ODM89498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M948"/>
    <dbReference type="STRING" id="48709.A0A1D2M948"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="3"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM89498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25620" checksum="89AEEFC2DC9E6A17" modified="2016-11-30" version="1">MSGTGNINLMIHLRGHKHDFDNWANLTGDPEWSWEGVLPYFKSYEDYQDLGDEVNHGYKGELRIERPDYIGLAPEFVRGAEELGYPNVDLNAPYSEGFDVIQYPIKRGVRQATYKAFIEPVRYLPTLTILKYSHVNKILFKDNVAIGVSFDRHGVPKTAYASKERRNSWPPTKLLMRFPGVGPREHLEELNIPVVADLPVWKNLQEFYLSPFFDAGRHEQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M982</accession>
    <name>A0A1D2M982_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002563">
        <property type="protein sequence ID" value="ODM89528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M982"/>
    <dbReference type="OrthoDB" id="8007085at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="24631" checksum="42EB40B335DF5DFF" modified="2016-11-30" version="1">MTLVQSLGIKLLKGQLKDPLKKQCRTGSDLQMQETNQRMLPVSKRTRRRWRSKQAQQLIESSEVLSTNFPYDIYPVQTLVDNNIMTECRYKSTIDLDEILDEPQYFPFSNSSSSSDDEFDFDDDVEFRNKIAKWACDNSDCLKYGNLSNFSAFPFENEMQYLKTFLRSRRYNLQQVVRRVSEMETAKCSNEYKCVKDLKYYKYNEVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9D1</accession>
    <name>A0A1D2M9D1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_17097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably involved in the biogenesis of the COX complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Mitochondrion inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002523">
        <property type="protein sequence ID" value="ODM89585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9D1"/>
    <dbReference type="STRING" id="48709.A0A1D2M9D1"/>
    <dbReference type="OMA" id="WRYINIK"/>
    <dbReference type="OrthoDB" id="10040024at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF2">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM89585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="167" mass="19213" checksum="A2BF0033A32B7069" modified="2016-11-30" version="1">MLVIPVSTLALGIWQVFRWRWKLGLIAEMRRTTLADPVPLPRKIEKLEYRKVQVKGEFDYSNQVLIGPRALVSSEDRTSGRQMSRGVFSSGSTRNGYHIITPFKVEGNGETILVNRGWVESRNFSKYNHVQGSTEIVGIVRKTEQRSPFITKSRPGENLLHFRQDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9V5</accession>
    <name>A0A1D2M9V5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002388">
        <property type="protein sequence ID" value="ODM89765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9V5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="18152" checksum="B597B1408101ABF0" modified="2016-11-30" version="1">MASDKRRNHPETQGSEACSSNKQRRITRSMVIALEKGVPDRTAVVNAQQNEDLRRKPVIKRLNPKRKRKAKHHPGLDLLHEQTYRSLAMPDQGPAPGTYDVILFDTRKAVALPGEIRHDPSHRVDMNCLFRTDFIEALDKEFHLKRVSKVRLDEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9Y3</accession>
    <name>A0A1D2M9Y3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_16900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the P4HA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01002375">
        <property type="protein sequence ID" value="ODM89783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9Y3"/>
    <dbReference type="STRING" id="48709.A0A1D2M9Y3"/>
    <dbReference type="OMA" id="YNTIALC"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013547">
        <property type="entry name" value="P4H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF244">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08336">
        <property type="entry name" value="P4Ha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0847">Vitamin C</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903675" description="procollagen-proline 4-dioxygenase" evidence="14">
        <location>
            <begin position="27"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="15">
        <location>
            <begin position="540"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM89783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="660" mass="75533" checksum="61FFA9B46F2169A7" modified="2016-11-30" version="1">MHFFRVFYLSLMVFLLLQVKQTLSHAQCGGRYPKPNPRTNYEDSGYPKSGNNWNPIPPEFYEGEDIFDIHGLFNEEDLNIINDEDDHYRNDPETRRNTNDYEHGYRVKIEVENGQITEQDNEVSVRKLETQLDEDSRDDYGSELQEPTSLYDFREDAEERIRPHYALDHRKAAKLALVEEMVYIKLKANSLFNSRDKISSFDDRCYKSLKQYLKEFEHDTKALNGTTGYIRATTVTANPLLTFRMIKRIVLGVTSSLMEICAQDGRNSEIIEAIKSSFSASNLTFPTRLDLNDALLGITRIQFAYGLNASDLCIGKIGDLHTNVTLNIDDSLELANYLMELKAYVLAYQWLTAAARSLNDVPKGDKKLATERVDSAWERLLTLIKLKQRNIVDQALRGKRQELIDEFSSYAGYATCRGEFDISDKEQAALFCFLNTKAHPYWTINPLKVELKKSNPPVWQFHDFLSDDTMAHIKKAAIPKFSRAGVIHDSKLRTEYTDERTSMSTWLSDYDSNNVRDPILFKLNKRMELLTGFAIIKPQSSHALQVVEYGSLGGHYEFHWDATEKPTEWSGTGDRIATLFMFLSDVLAGGYTAFPYLGIAVRPEKGSVILWFPLHLNGKPDFRTMHGGCPVIFGTKLAANKLILHNENFLKYKCSLNPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAH0</accession>
    <name>A0A1D2MAH0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16759</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002288">
        <property type="protein sequence ID" value="ODM89929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAH0"/>
    <dbReference type="STRING" id="48709.A0A1D2MAH0"/>
    <dbReference type="OMA" id="EHKQCYN"/>
    <dbReference type="OrthoDB" id="427960at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.60.10:FF:000034">
        <property type="entry name" value="Universal minicircle sequence binding protein (UMSBP), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47103">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47103:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="7">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="7">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="7">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="7">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="146" mass="15608" checksum="1A672678A95219E7" modified="2016-11-30" version="1">MSSGSVCYRCNKPGHFARECNESDDGGRGGGGGGGGGGGYGGRSRNFGRGGREKCYKCNRFGHFARECREADRCYKCDGVGHIARDCTRTSDEPMCYNCRKSGHIARSARAAGQSQTCYNCGEQGHISRDCPNPKTDRKDDGGGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBB1</accession>
    <name>A0A1D2MBB1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002128">
        <property type="protein sequence ID" value="ODM90174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBB1"/>
    <dbReference type="STRING" id="48709.A0A1D2MBB1"/>
    <dbReference type="OMA" id="MAYHEVT"/>
    <dbReference type="OrthoDB" id="1734063at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903752" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="969"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="744"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="800"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="970"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1032" mass="110739" checksum="2E40AD5400C3236E" modified="2016-11-30" version="1">MPGTTRFVPLLLSVASVLLGSVQSNPSPQSIPSTSRAPPPLPQYYPSSSQRPPSTASSSLSPTAPLYTAQRIRPSNGYEDDEEPYPASAHLGTARTTSGAEDQPENTGFVEAIDFSSLLKDVGSSPKGPGLDIGASSSNPLFASESKDTFNGFFGSSKNPFEELTRLNTASSDHNSRQSNDDENSGFVDPNVQFRSLFDSTGTSGGFKPQDFLGSKSENIGSDPSKGSQTRAYPSFTYSGRKNVEREDDDYRGGREDGPSNRYRSSYRQVGNNNNNDYYNRDAGPGPVRQYDDDRISNSPPTDSYDDEGPSSGPSYYNNGPSGPSPRGGGGGPGPRDNRDYDRATPRYSEAAQETSHAPKTQPRAAESKNPKCKKVEKSVEYSDDYSSFTEPESDYDPSTYQGRYKRQARQGGRGKAAGGKRPMTCYVCEDEQGRYAEKCSYDSNGSPKNGEYFHSESSSFSDNGNKRRPNSGGSSSKDRTRRNPNRQRSGGDIASAESTTKSVSTKPEDAPEIAESEPKVIDKRQSGGGDFGGGGDDNDDFGGNNNDRGNNPQRDEFGDPYDSRTGRYQNPSGYEGPPLGATGGRGGGGGGGDAGFERDFNYQIPDYEREAASATREFDFSIPREFDPDVQLRGGGNNNNRGGSGGRGGGGGRASTGENPHSFLSGGRSGENPHSFLGGGRSGDSPHSFLGGGGQNRRSGGGGPHQSASNRRENLDAFDVGYSDYLRQNFPESLNSPGFSTENFPSSSNFGPSNYEYSPNYYHRPRGGGDGGGNDDRDERRQGAEISNSPSNHHNNRGYHGGRGGDRGGGGGRGGFGSGGDRGGFVPDKEHTQPSHNFAPPPGFFSEDSPAAHPHENYENLGNYMKEFSSKTRDGCHKVNKGDMTCYVCKDARGMNKEECMYASNDPKNKAMAYHEVTEYSSPTASILPAPLHATLLGLVKPSTEEDGTKEGSLAAASSNLFSLIPEESQVSSTVTPASTGKAKKTTPSNNNDKKKDVRSVKATRYAHSSTVIVHERSKRSPKEEEYDFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCU2</accession>
    <name>A0A1D2MCU2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15978</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001837">
        <property type="protein sequence ID" value="ODM90704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCU2"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="289" mass="33811" checksum="03C321F00B28BF46" modified="2016-11-30" version="1">MIPYVKEKLPKLREKRAKKLFKGISDPDTSRKRKIFKCVLCGVLSKGKHTMRIHLATHHSQLYENLRKSNSIISLDCRECPEAVSFGSEEEIRIHIELVHPDKCSRCPECDKVFLDGASNELDDHIRLEHDGEDDKDDLKMQLKMKSNVTREVTPGSKRKRRKSSSGFKYHCMRCEMKYNELEEISDHVKEEHPQNFWPCAYCKLMKYTERGLLFHSQMCAKRPRIGEEGKRPRASIKGWKERQEEQLVSFDRIPVPCEICEKTICLYSLMKQYSQSYGCPTCRRGSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDI7</accession>
    <name>A0A1D2MDI7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_15610</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001681">
        <property type="protein sequence ID" value="ODM91076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDI7"/>
    <dbReference type="STRING" id="48709.A0A1D2MDI7"/>
    <dbReference type="OMA" id="LPGELAX"/>
    <dbReference type="OrthoDB" id="6754682at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000016">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="18"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM91076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="13718" checksum="1989D504AFC1EF55" modified="2016-11-30" version="1">MPPKTSGKAAKKAGKAQKNITKGDGKKRKHKRKESYAIYIYKVLKQVHPDTGVSSKAMSIMNSFVNDIFERIAAEASRLAHYNKRTTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME09</accession>
    <name>A0A1D2ME09_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclic AMP-responsive element-binding protein 3-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15453</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001623">
        <property type="protein sequence ID" value="ODM91230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME09"/>
    <dbReference type="STRING" id="48709.A0A1D2ME09"/>
    <dbReference type="OrthoDB" id="674948at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14689">
        <property type="entry name" value="bZIP_CREB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051381">
        <property type="entry name" value="CREB_ATF_subfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45996">
        <property type="entry name" value="AGAP001464-PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45996:SF3">
        <property type="entry name" value="CREB-H TRANSCRIPTION FACTOR HOMOLOG LET-607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="275"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="293"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="57511" checksum="5E75819065EC12C5" modified="2016-11-30" version="1">MQLFGYYLRDLKKNSNMDNLTGGLLFNDTMVMIAGGSANGGSNSSSDVEFPERLTYEYDSSPCSSASSNSPVYFASGAQNQDLFNEFNAFELANETLLASNASHDESYMEELISSDLSSDEDKFLESIRYGGGLFSSGNDLLSEEELVNTIQNYGDVKVVQVDSGAEPARATHRVIEVVETNERVAGTKKRKASVGGVKNVKRAVVIQAEKMEELKDELIIEAAEPEDIGSPGSPQEQHTSFQELKLSDEEKRLLSKEGITLPSHYPLTKLEERELKRIRRKIRNKISAQDSRKRKKEFLDRLQQRVQEVEDEKSSLQKRVRSLESINSKLNAQVKRLQQALQSATQTAQSTPKQTVVPAATTLLVLILSLALVVLPTVEKNSHEQNTNEIISLLNRSNELGNKNIGRLPINVNKANIPRSRAMVAEHEIDMDDDGNNVVELIGEVQNVLMRMRGRKRLREGKDKRIAKHGRFGAVQWGARQDSWWESDDEETIDNHNVHTHAFRAVDEIEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEH9</accession>
    <name>A0A1D2MEH9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucan 1,3-beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001618">
        <property type="protein sequence ID" value="ODM91261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEH9"/>
    <dbReference type="STRING" id="48709.A0A1D2MEH9"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="159" mass="18030" checksum="AAC5FABE17D08C6D" modified="2016-11-30" version="1">MTMINLKLHTGNLAHQLPNHSSKPSLDDPTYAHCNGRPQCEMSYSIVAKRSSNVYLYGAGMYNFFYNYDQTCLDTENCQDNMVNVEGNNNLYMFNANTKASVNMVVRETIKYSLVKPITRTVSVNPSTLSGRIIINYFNLYLISTMKNELIANKNGKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEN6</accession>
    <name>A0A1D2MEN6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001546">
        <property type="protein sequence ID" value="ODM91435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEN6"/>
    <dbReference type="STRING" id="48709.A0A1D2MEN6"/>
    <dbReference type="OMA" id="WNANSIN"/>
    <dbReference type="OrthoDB" id="416454at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061343">
        <property type="term" value="P:cell adhesion involved in heart morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007508">
        <property type="term" value="P:larval heart development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33395:SF22">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33395">
        <property type="entry name" value="TRANSCRIPTASE, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="83"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="59328" checksum="37619B4FDAA42365" modified="2016-11-30" version="1">MCISETFLNDNKDIIGFSDFNHIRGDRDLILTNKDKGGGVLILTKKSLMSCEYKLMCSEIIRESSNIEIVAGRVKDRHMKAIIVCCVYRPPNYRNEFLKNDIVAIDMIVTELINTNRPFILCGDFNLKHASSYQKLVEVMKKHKLSQLISSPTRGNAVLDLIITNHPELCTSTTVHDPMISDHKQITTTLIFQRKQREKKTFTYRNYNNININSFHEDIYNAQIDTTNENHAQCIYNELHSLTMNIFNKHAPTLQKTITVRERPLKLSENTKQLLRIRDSFDKQDLHNPEYIALKKAVKRGIIGDKKSEVDTAILSDGMWPTVNKLLNNKNTNQGEFPFTVDEINEHFTKICCNEQTNKEHAPTYQQWTNNYSHETEKFRLEEISYVTVKFAWRSMKKKLNSSEDANGISNRMIDMLIKNDVAITLITSLFNASVRDKFVPPELKRARIVAVPKTTKIASLNDFRPISILPVLSKLLEKCVYLQLIKYITSNKILSDSQFGFRPKHATFSCRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MER7</accession>
    <name>A0A1D2MER7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cubilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001584">
        <property type="protein sequence ID" value="ODM91351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MER7"/>
    <dbReference type="OMA" id="YHRTLIL"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903909" description="Cubilin" evidence="1">
        <location>
            <begin position="17"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31298" checksum="F9C5FC7706E98525" modified="2016-11-30" version="1">MLISTLVLIYLGVVGAAISDRQTGTVKQAEKTALDSGRSLEFADALNSTNCGDLLVSKGGFITYKQSKNDERCIWTIRTHKWETKFLMHESTFVSESDHVLIYSVDENGDLQVKAKIDKETGREIVGVLGPLLFLSFTSTKGQEFLLEYFAFGYNEATGYTYGHAHLDKPSGNLVWPEKPVDYYQNTFSTFTVSPNLVDTRLQLTVDTVDLVSLSRGCQNNFLTVHQLFESGFVLRLRYCEPDLLSSAEISSSSPLLIIYRAAVGPTNVGISFSWDESKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGY0</accession>
    <name>A0A1D2MGY0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme E2 J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001282">
        <property type="protein sequence ID" value="ODM92266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGY0"/>
    <dbReference type="STRING" id="48709.A0A1D2MGY0"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000086">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="46"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="327" mass="35918" checksum="25C19771C8E3579F" modified="2016-11-30" version="1">MNLRQDESRGESYIKSSGRCRCAAAAESVSKTAATAPVASYNLRCPGVKRLMREAAELATPENEFSAHPTETNLFEWHFTIRGPEGSEFEHGIYHGRIIFPTEYPMKPPSFILLTPNGRFQTEEKICLSISNYHPETWLPSWSIRTALVALRSFMLTPGNEGAIGSINFAPEERKKLAIKSRNWSCHECGPIIKLLPVQKPDNSNSAKEVGNGDATVEGKTSDAAPPTPQATDVVPKRQTSAEVAPTQNGHVKDSNPVTSPSTAAPNADNQDAISARNLETNNFALEQQQQHNEPIKNIIYDLGIGCFVVLILALCFRRLLSIFSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI48</accession>
    <name>A0A1D2MI48_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine palmitoyltransferase 1</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Long chain base biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Serine-palmitoyl-CoA transferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_14060</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01001183">
        <property type="protein sequence ID" value="ODM92625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI48"/>
    <dbReference type="STRING" id="48709.A0A1D2MI48"/>
    <dbReference type="OMA" id="LTKYGCG"/>
    <dbReference type="OrthoDB" id="3168162at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF2">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="15">
        <location>
            <begin position="99"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM92625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="519" mass="58658" checksum="2CEB500016A34D74" modified="2016-11-30" version="1">MLNAVLAFFYRNLIGAPSYHLYLEAFLALWLFWLIRQRKKAEKKKLLTAEEEETIINAWQPRPLVDEKELDKMEGYDNGDVWGPISGRPGKYVEIDGEKYLNVATHNYLGLMDSTELDDAAEQCIRRYGVGSCGPRGFYGTVDVHIKLEEKIADFLGLEETALYSYGFAAVSSAIPSYAKAGDIIFSDELVSFPIQRGLAASRSTIIYFNHNSWEDLQEKLEEQRKTDKKNAKKAKTIRRFCVVEGIYSKSGTLCPLKEVADLCKQYKVRLFVDETISFGILGKTGRGLTEHLGVDIKDIDFISGSLEHGFASFGGFIVGPSYVVDHQRISGLGYCFSASLPPLLAGAGIKALEIIEQNPDIIEDVQDKCKYMHKSLDNILTFFKITSEELSPLKFLYLVGCKVLPWEVTRELIEQVIIYVKDNYKIALIQPSYLDSEHKLPLPCIRISVNRLLTYKEIDSIGNAIEDACNALNIFDSIIANISDEDAELRNEMVSEYEAYLKAKEDKQSRKAVLEEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIJ8</accession>
    <name>A0A1D2MIJ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13866</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001140">
        <property type="protein sequence ID" value="ODM92809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIJ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MIJ8"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF397">
        <property type="entry name" value="CYTOCHROME P450 2U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="8708" checksum="30734717CA1A05AC" modified="2016-11-30" version="1">MKTKIRVIHHEALMPFSTGRRACIGEGLARDSMFLFIANTLQRFNIELDPEFPVKSAETLAGLLWTAKKPSQVCVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIT1</accession>
    <name>A0A1D2MIT1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphodiesterase</fullName>
            <ecNumber evidence="9">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13794</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Vital for female fertility. Required for learning/memory.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01001124">
        <property type="protein sequence ID" value="ODM92889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIT1"/>
    <dbReference type="STRING" id="48709.A0A1D2MIT1"/>
    <dbReference type="OMA" id="MMKERCG"/>
    <dbReference type="OrthoDB" id="189220at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007615">
        <property type="term" value="P:anesthesia-resistant memory"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048675">
        <property type="term" value="P:axon extension"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001661">
        <property type="term" value="P:conditioned taste aversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007619">
        <property type="term" value="P:courtship behavior"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046958">
        <property type="term" value="P:nonassociative learning"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008355">
        <property type="term" value="P:olfactory learning"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007614">
        <property type="term" value="P:short-term memory"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040040">
        <property type="term" value="P:thermosensory behavior"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1300.10:FF:000001">
        <property type="entry name" value="Phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040844">
        <property type="entry name" value="PDE4_UCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18100">
        <property type="entry name" value="PDE4_UCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0114">cAMP</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="11">
        <location>
            <begin position="294"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="370"/>
            <end position="374"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="529"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="529"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM92889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="626" mass="69573" checksum="F20DF8978FE8DC03" modified="2016-11-30" version="1">MSVTDLRVSSGSTGELTAEGHGNAPLGPHKLPRTLSTSVLRIKHRSSFWEKFGADDNLVVRKETHGDDLIVTPFAQILASLRSVRNNYITLTNVPTHRSRRSSSSAGGPSPQPKHNVGDDNYTKLALETLDELDWCLDQLETIQTHRSVSDMATSKFKRMLNKELSHFSESSKSGNQISEYIFSTFLDKQQELDLPSLRIDEVEGPSTSASIISQKALAIEARKQREKHAKVASSVGVGLPAVLQAPQHQAHGVVEGAAPSQQKPQHPMSHITGARKPLANVINLSERIPKFAVDTPYEDELGAHLDDVDKWGMDIFKLDELSNCRPLTAVCYAVFQERDLMKTFKIPAKTLVTFLMTLEDNYIREVPYHNSLHAADVAQSTHVLLKSPALESVFTGLEQLAAIFAAAVHDVDHPGVTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNEEMDILTTLTRKQRTTLRKMTIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVGAPEHGALRDLSNPTKPLGLYRRWVDKIMEEFFCQGDREREQGLDISPMCDRHNATIEKSQCTRCGDVADLVHPDAQDILDTLEENRDWYQSMIPPSPPPSAGSPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJI7</accession>
    <name>A0A1D2MJI7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">N-acetyltransferase ESCO2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13520</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. ECO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001058">
        <property type="protein sequence ID" value="ODM93160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJI7"/>
    <dbReference type="STRING" id="48709.A0A1D2MJI7"/>
    <dbReference type="OMA" id="DHARSHF"/>
    <dbReference type="OrthoDB" id="428854at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028005">
        <property type="entry name" value="AcTrfase_ESCO_Znf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028009">
        <property type="entry name" value="ESCO_Acetyltransf_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45884">
        <property type="entry name" value="N-ACETYLTRANSFERASE ECO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45884:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE ECO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13880">
        <property type="entry name" value="Acetyltransf_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13878">
        <property type="entry name" value="zf-C2H2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="N-acetyltransferase ESCO zinc-finger" evidence="10">
        <location>
            <begin position="62"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase ESCO acetyl-transferase" evidence="11">
        <location>
            <begin position="218"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM93160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="289" mass="32953" checksum="FF716C26851272F4" modified="2016-11-30" version="1">MSDADQNGKKLFPIFDKTFRPRKPDPLQEIQHTLQKCQMQQHHLAKRRKCLLGKKETPGLTQMILDAGQKEIGPVFCAECGLLYSPGDIEDEKEHRKAHSRLENLFCIRLWKGANIVQEFPTEACIVVQIDCSKESKRVLNAVKDFLAWLDSELGADYEPCGTQPSEKILLYLFKTRRKNAFRVLGCCVVETIDQEKISCRPIEFNNAQGNAETDEKRILLGITRLWTDTVFRNRHIASRLCDCIRLNCGIPGIIISKNQIGILEPSEDGKTFMMKYTNNSGVQYGYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK41</accession>
    <name>A0A1D2MK41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001020">
        <property type="protein sequence ID" value="ODM93338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK41"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="64" mass="7267" checksum="057C89CCE968AC90" modified="2016-11-30" version="1">MPIKYTEISGPLAERMLARQNKAIYAELFVQFGPGKCFLPKYYSEHSDVIENFEAPLGQKKCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKB2</accession>
    <name>A0A1D2MKB2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000979">
        <property type="protein sequence ID" value="ODM93459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKB2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="24" mass="2623" checksum="7B87EBC4AFDF952C" modified="2016-11-30" version="1">MRTKKLVGFGRMAEPGVMLSSTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMG1</accession>
    <name>A0A1D2MMG1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein tamozhennic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12434</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000836">
        <property type="protein sequence ID" value="ODM94256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMG1"/>
    <dbReference type="STRING" id="48709.A0A1D2MMG1"/>
    <dbReference type="OMA" id="THDALWK"/>
    <dbReference type="OrthoDB" id="9837000at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048839">
        <property type="entry name" value="SPATA2_PUB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15326:SF2">
        <property type="entry name" value="PROTEIN TAMOZHENNIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15326">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21388">
        <property type="entry name" value="SPATA2_PUB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="5">
        <location>
            <begin position="1003"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="480"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="530"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="627"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="776"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="851"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="682"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="722"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="780"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="805"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="852"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="901"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="917"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="940"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="959"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1141" mass="128216" checksum="C5ECFB65777C66F9" modified="2016-11-30" version="1">MKLTNQFQAVFCSPSTTTVLGSRVRSSKIGGGRVMRGSACSEAIFHDHQMLTLHSTFTVRRRDLHEKEGWTLPKIFFVDFQLLYPSFRAPPVFLKAFGPESVVELNRNIIVQHEDYLKQDDPDKKADALRIRDSISSFGATRVKFTYRETERVLHNSAMNIGEFDPREGCLAFCHLAKYAENLLEQPWRKDFHVIKLTSGFWVHNIAAQLQNAHEILIVMGYVNLDERTLKLLPTLNYNKLKEVSRDCHIASRECLILSQIWQHVADQEPDYPLTIGEVFEYRKNHLGDTDTICNKLLYDIRQRMHTAKQLQHQQQRASISLKTAHRFVPVDRLIDYDMEETLNHDEPDMTIIPEREMDRAQEMMKNVNLTHNHQYGVRQADEDEHIYDPVYGSSAAHHDSLNYPRRNSHHHQDRDLYYQHQQQQLQQQKSNNPYYCSRKSMPAPSNIANQYQYHQNTNGLSQRNSSVSPMIPMTVTSLFSSNPSPIGRNQVSKSNSMNSISSGGVGGTPSQLNQLINQPLTLSKVKETDLDGELPPPPPTRDVYYNNGIGTADRNNRSRKSMPSTAVYADEFYPPGIVKPVAVYGSTINNLGAAGQYPHHPMRPRQNSDNGEDVLNEAYAYASEINQMPKGTPPSYLAKGQAYQHQATPIPPNSDSDSHSEKSRGASIQRDLAHNEPTAISKGRSSSSTDASSSWEGSVLEGNYGGNRVAYHQQNGNKMNRKTETPKRPSHIDIRGSSSSGSGGNKDWRSSGGAGAIDTIELENEKGALVSQIRYADSSPESDVIQQQQPSRPNNKGAYREPNSSSSGSCGSPCSASSLGRNFARNEELSSLDTVYYDYLLKQGKTDQVIKNVPKNNNSENNVMQQENSRRQASSSSRSSSHHQPQTQQPTNFNCEPDLDENHIYDGRRVVKKKQQNSSPPKNSDQSQMKQKRVPVESTVPSASDYNMSSSDQVSKPAHHDKNMMRKNRNAEEQKHRKERLIPIENEIPAPAPPLKKPVEPWNCRFCTFRNTKEERICEMCAKSKDFYEDDAVDVAGAVAIATATAPVEPQLPKLYSQAVSNVSKPAAQASSSSVATSLVSSEEKECPQCTLLNPIRARICDACNYRLIPVESPRNMDDLQQPDNRSVPIIPCHFLLVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMZ9</accession>
    <name>A0A1D2MMZ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000806">
        <property type="protein sequence ID" value="ODM94429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMZ9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.820">
        <property type="entry name" value="PHR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038648">
        <property type="entry name" value="PHR_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="21816" checksum="FCFF9B11AF590FF5" modified="2016-11-30" version="1">MTAVYSVSREIKKATDKSGQPQANDYGGCFYTVAFTTDREIQLLGLKFYGPAKQNVGTYLVDYKIVKTVEVENEYPGLVAWIGESFLTLLNYLNVWDIFGPGPYVREVQLFQPKSRVTIPMVAKGETFTVQFPRPVVITPNELTEIKFELVGPKTEYGVVRYDPIVVPLKDESHVTFNFLRGSCQLPEVLFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNZ4</accession>
    <name>A0A1D2MNZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000785">
        <property type="protein sequence ID" value="ODM94575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MNZ4"/>
    <dbReference type="OrthoDB" id="2588702at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12510">
        <property type="entry name" value="RRM1_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050666">
        <property type="entry name" value="ESRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13976">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="93"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="94"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="24017" checksum="F9BAFC56ABACCE43" modified="2016-11-30" version="1" fragment="single">MSVIIRLQNLPLTASSIDIRNFFHGLSIPDGGVHIVGGINGDSFIAFSTDEDARQAMRLSGQHLKDSRVSLLLSSRNEMYKVIEQARLTAIGGPQASSLPPSSSSAMSPQNANNPPSHLASQSQQGSSSNGHGHMQHQHQHPHYQQHHNIHNSNPMSPTSSGSSANDYLKGFSGNTSTGSGNNTASADLSSNPALLFSTMSSIPSATLGGTNANPYLSHQGGQGFPGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPL9</accession>
    <name>A0A1D2MPL9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Centromere/kinetochore protein zw10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000722">
        <property type="protein sequence ID" value="ODM95007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPL9"/>
    <dbReference type="STRING" id="48709.A0A1D2MPL9"/>
    <dbReference type="OMA" id="NIDITHD"/>
    <dbReference type="OrthoDB" id="534815at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="2">
        <location>
            <begin position="603"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="749" mass="84569" checksum="FBA08A4B658FA5CD" modified="2016-11-30" version="1">MSTCDGSVSILRDALVDVDRSKCEKIHSLFGENATIDEVNEILRTLDSKISQLKHNVVQSLHTTFVLYETDVDRVVEWYTEILDAKEQADKLENQLGQDKQILHSANEDLEIINCELGQCQASIVLLKSLVDIVKNLERADPADYYNAARLIKESEDELASIASSFQIAEDHIWIKQLRARFTDLVVDVYDKCRKEWGSLFRFDNNTLTIYPHAANIEQLITSLRNIKSFSRVWEKFLNMLWQELFKPACSTEFKIEVCGSDSTVSLKYEADDVPTRERDSFIGETSFLQVNDRRDRERDVSTVIRAKKLDKPFSNAVELFGNLTALVAGINSIFCDNPAEMASLANVIGPKICNELANKYLKTLILQRCGGDIEIARADVAHMKKFVTYLADEMNFHFPDPNIFQDIDANFDILFKSQVREALIVKLRDLIKSDVHNSEEINYEVSIPNSKLSAGEIILLRKNPALFPRCIVSKSIAELVKLLKEHMTRYPKDVGMSASVLSLYLALVKIPKHEADAGELVPLTSVLIHNNSLFLAHHAGYTFELCDDMVPDLRAKASQAIAFMMRSVRSKLNELISTAMSSIEERVDRNIDITHDFLVITAELKRLNTVMSGVLPPLSWHDILATLVDHTTNEMCSKVLAWDDIPANSASELATAFTQFAVATSSLFKGDASTPREIEALTSRAVKKWQRFKLLIFVLTASMKEIESKWVGGCGPLAIEYSAEEVRRLIRALFQNTDRRAAFLTTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPS5</accession>
    <name>A0A1D2MPS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Troponin T</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000712">
        <property type="protein sequence ID" value="ODM95099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPS5"/>
    <dbReference type="STRING" id="48709.A0A1D2MPS5"/>
    <dbReference type="OrthoDB" id="330499at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005861">
        <property type="term" value="C:troponin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005523">
        <property type="term" value="F:tropomyosin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006936">
        <property type="term" value="P:muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006937">
        <property type="term" value="P:regulation of muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027707">
        <property type="entry name" value="TNNT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038077">
        <property type="entry name" value="Troponin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11521">
        <property type="entry name" value="TROPONIN T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11521:SF1">
        <property type="entry name" value="TROPONIN T, SKELETAL MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90250">
        <property type="entry name" value="Troponin coil-coiled subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="453" mass="52458" checksum="FDCA9A8B1A043C5B" modified="2016-11-30" version="1">MADTAVIEPDEEEFYSADEAGPTPEPPRTPLPPDVMEEIASITNKLVKFKEKKNPEIEDTLQLFINEWRHQTKSEIEDLKVLKERVTIRKSQRAEEEARFAEMRREEDEMLARMAEEEKIRKQEDKIKRLQDAELKRQKMMEEQSKGRNFKIASTAKDKGNALDTSKEPTPEEYAAMKEAALSVIIKPIGELGALRKERLKRRAQELWDKVVLLETERYDVEERRARQEYDYKELKERQKQQLRAKALKLGLEPEALTGRYPPKIRVASKYERRKGLRPFGETKGLFEGADMPRQIIKQIEEEEAAIKAVILKQEMEAKAALIAEEEANENEEEVAEEDAEEERETEEVAEGDEEAAEENEEAAEQDEDTIEKKEIVITDEAAPKRGKKRLRQRQQLRTATEEVEEEEEVASTAATKKFVVEEEEAAPEKSSSPAQQQEEEVEEEEAEEEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPT3</accession>
    <name>A0A1D2MPT3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vacuolar protein-sorting-associated protein 25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ESCRT-II complex subunit VPS25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11624</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPT3"/>
    <dbReference type="STRING" id="48709.A0A1D2MPT3"/>
    <dbReference type="OMA" id="PFYTVQP"/>
    <dbReference type="OrthoDB" id="245150at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.570">
        <property type="entry name" value="Winged helix' DNA-binding domain. Chain C. Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008570">
        <property type="entry name" value="ESCRT-II_cplx_Vps25-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014041">
        <property type="entry name" value="ESCRT-II_cplx_Vps25-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13149">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13149:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05871">
        <property type="entry name" value="ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="191" mass="21706" checksum="558A0ED334C84292" modified="2016-11-30" version="1">MAAGSSNFFEQFYNFPPFFTLQPNPSTRSRQFEMWTKLLQSHCANANQFILTRNEPLFTNNEISRDLSEEFITELFSYLIDNDHAVPNKPGASTVIPKAKGSKLPSAQGMDSLVIWFMPKERWFEKLYDYAKKNGLQNGGIATSFEILQDESFTGMDDRVLAILLNAMMETRKCEVMLGGDGITIDGVKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRA3</accession>
    <name>A0A1D2MRA3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongator complex protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000652">
        <property type="protein sequence ID" value="ODM95573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRA3"/>
    <dbReference type="OMA" id="QCHEDNS"/>
    <dbReference type="OrthoDB" id="9995306at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018627">
        <property type="entry name" value="ELP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184:SF6">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09807">
        <property type="entry name" value="ELP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="29768" checksum="C9836B2C9F82A24B" modified="2016-11-30" version="1" fragment="single">VGITEDALFTGKGSVNVVHQFGETVEGGFLNHFMLTQFFRKFSREQDNARALLILNHHTVAHWTSIASKLGTNINVLQESGKLIVIDLLKDIYEKLKTNPTRSASANDHVDLQNLFTRCHQTVEDFRKTGSRRILVIIDDLGGILAANGGSAEATFQDSEKNLLQFLVKLKALSVQCHEDNSCAVTITCLVNSPELSTDSLELSRFAKTVSQVLPSVLFEVAPLSTGFSSNVTGFLKVVYKPRKSDCTNKVVEKAFMKNYHFKLDSNCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRY3</accession>
    <name>A0A1D2MRY3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal phosphate phosphatase PHOSPHO2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000623">
        <property type="protein sequence ID" value="ODM95766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRY3"/>
    <dbReference type="STRING" id="48709.A0A1D2MRY3"/>
    <dbReference type="OMA" id="HNLADCF"/>
    <dbReference type="OrthoDB" id="10267182at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016965">
        <property type="entry name" value="Pase_PHOSPHO-typ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889:SF12">
        <property type="entry name" value="LP01149P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889">
        <property type="entry name" value="PHOSPHATASE, ORPHAN 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06888">
        <property type="entry name" value="Put_Phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031051">
        <property type="entry name" value="PyrdxlP_Pase_PHOSPHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="33189" checksum="066007E7C07B51F8" modified="2016-11-30" version="1">MAKSGKLAKKSCCHCLCSCEDEEQVAYLYAFDFDHTIVDQNSDTAVMEIIHDPIPDNLQRMYDGTNWTEYMDQIFRFVADEGGTYDVIADKISLLKPTEGLFVKPFQGQLKTLPTKFTLGLSNSRKCVLGMIELLQRISESRNVHHHSKLVVISDANTFFIQTFLTSRRPPLIADAIITNQADKTDEGYLKLTPYEQQQACPLCPRNLCKGAALERYIELKGPFNKVYYTGDGGNDVCPAMKLTENDVVFVRKNFAMEKIIAHGNWKGQNIDIKAKIVYWDDAKTIEEEMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT53</accession>
    <name>A0A1D2MT53_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine--tRNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000577">
        <property type="protein sequence ID" value="ODM96112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT53"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="17771" checksum="941858B5D34A7237" modified="2016-11-30" version="1" fragment="single">IISGSFGGTGGGGGGSSLKGGGGGDTEESSFGPLVSSAGLIFTLLAPLLLTVLFSLAVLLFLVIPSSTSGGGLSGSGGGGKPIPWDEAAVLLRHPTRNEASDDNRIHWILIIQNGEAKPPLPFRKLDDMRLGTPHGETLEARDPSDFALTKRSEPWNRFWRLPPTKALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTA8</accession>
    <name>A0A1D2MTA8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Snaclec 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000553">
        <property type="protein sequence ID" value="ODM96317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTA8"/>
    <dbReference type="STRING" id="48709.A0A1D2MTA8"/>
    <dbReference type="OrthoDB" id="418245at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="547"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="632" mass="71300" checksum="DA4F5E9C5119F6CB" modified="2016-11-30" version="1">MSFYWQFQGQGNWFLLELKPTPFHVWGFMRNEYFIEQLKTDKTLRFRSVVEATTSVFEQNLSVIIRPDCYLLLKVEDNTQLTLDSLWSPKTDNRGLNCTVFIVPKKNFGLEVKLSSLSVYGMRDICKGRFLQFTRPKRIPYNSPGSTSGRAGGSSTVYTASPNVESELKYNQNNNFVENIHFALNNPEERQPQAFSPLERKFCGKLEDYLESERTLTFPSSESTLLSSSTSFTLDNFDNEIPGILSNNIPTTKIWGIYLSVKLPVAVKVREGFAFDLTALSPCQRVTLNGLEGELKYSKHYENEQCSVVIHVPYGNTILTQIAVSSDALKISAPEENPIRSDIISSVTSVNVLSSESPELGNLDPDISVPISNESVANWAQNYNSSNINNTNYVTEATASSKKDQQPDNMYFNTEALDNSIPLPPSSTSYECPVSLQLNELETNGINGGLLPLDPAENEDDDGRKQQLLQNQKYLLIQAVDMVSGSEFNWCFDASKQNAAHKRAWKSSGNRVSINFRLSHFDTFILNYESLKIPELVGDCERGWVKVDDACVTVVEKLVKWTDAEESCQLRGGHLVTIKNEHNEKKLEKLIKESPLFLPSRAYWIGANDRESEGNFQWTSGLAFHYKSKRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU86</accession>
    <name>A0A1D2MU86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dynein beta chain, ciliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU86"/>
    <dbReference type="STRING" id="48709.A0A1D2MU86"/>
    <dbReference type="OMA" id="AHEDISW"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="1">
        <location>
            <begin position="169"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="2">
        <location>
            <begin position="515"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="602" mass="69522" checksum="F21F1F03C4A9F885" modified="2016-11-30" version="1">MIIKWHLVWETLFKTHQNLKVKPICNDLNPKAVTNDELFGVINAATREWKDGIFSVLMRDQANMSADGPKWIILDGDIDPMWIESLNTVMDDNNNERIALTKMMRLIFEIYTLKTSHTCNCESGRDFVHQPTGSGLESLILLDNSIITNFITSWLEGRENAGEKANLTILFDKYVPTVIDMFKTRFKRITPMPEITHIQVLCNLLECLLVPEILPPECPKEWYELYFVFAVVWAFGSACFQDNMIDADFSKWFQQEFKFVKFPQGVPYLIFYIDNETKRLVPWSEKVPKFELDPDIPLQATIVHTSETIRIKYFVDMLMEKGQPTMLVGTAGSGKTVLNGDKLACLPETHMICKIPFNFYTTSEMLQRAMEKPLEKKAGRNYGPPGNKKLVYFIDDMNMPEVDTYGTVQPHTLIRQHMDYGHWYDRIKITLKDIHNVQYVACMNPTLEASQSIPDSRDILQFSRLGFLEWMHCKIFIKTFCSNIYQVLCINLVLLFRTLVSHCEHCVGTSFQSRSSFLPTAVKFHYVFNLRDLSNIFQGLIFSTFDCLQHPIDLDIQTFHKLLTDNVKKGFEDLDESILMAKPLIYCHFAQGIGDPSTCKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUG4</accession>
    <name>A0A1D2MUG4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vacuolar fusion protein MON1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_09944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an important role in membrane trafficking through the secretory apparatus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the MON1/SAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000508">
        <property type="protein sequence ID" value="ODM96727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUG4"/>
    <dbReference type="STRING" id="48709.A0A1D2MUG4"/>
    <dbReference type="OMA" id="AYTCVPL"/>
    <dbReference type="OrthoDB" id="272411at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032510">
        <property type="term" value="P:endosome to lysosome transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19038">
        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="4">
        <location>
            <begin position="149"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="5">
        <location>
            <begin position="315"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="6">
        <location>
            <begin position="442"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="577" mass="64792" checksum="BFC052E7F584A392" modified="2016-11-30" version="1">MDKSSSSVNTSGGDLEEEVVSEIPLESEPLSHRKLSDLQNQSGFITDDNLNGIIGESVGGENIPSGDDNADGNAFSSCIGSFGTKEDEEQQASSDPEALNVELTKALDDLSVTTSGSESEQVQSNGLENVAMRDDNDSDMSPLWRSQKRHVFILSEAGKPIYSRHGNEEKMVTFFGLLQALVSFVQSDGDTIRAVKVGETNIVFLVKSPLILVCVSQMSESISQIETHLMYFHNQIISILTSKQLQTIFEKRKNYDLRRLLSGSERLLNNLAGLIEVDPSFVLGAVRCLPLANTVRDSISQTITTILNKHKPPPSVVFALLVANNQLVSIVRMKKVFMHPMDLHIILNLIDASESFISVDSWVPICLPRFDSSGFMYAHVSYLAEDCQACLILLTTDRNSFFTLSEAKQKIVDRLRKQNCLDAINASMNNQWPTMSYVNVPEVRHFLYKAKYRAQFVAPVLDVPYLDHNSEDEEAPPEELSRDCPRAAKRISGELQRLYSTYYRMHSRLHAQARPVKIIYWVDDKENWLGWNTSNFELYVALEPLIKKSAAISAVNKLLKWVKKEEERIFIVNAPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW00</accession>
    <name>A0A1D2MW00_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retrovirus-related Pol polyprotein from transposon TNT 1-94</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000483">
        <property type="protein sequence ID" value="ODM96964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW00"/>
    <dbReference type="OrthoDB" id="413361at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057670">
        <property type="entry name" value="SH3_retrovirus"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25597">
        <property type="entry name" value="SH3_retrovirus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retroviral polymerase SH3-like" evidence="2">
        <location>
            <begin position="12"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17442" checksum="F117D83D7DF806C0" modified="2016-11-30" version="1">MVHLGHIKTFGCTAYKHVPKQQRGTWDAKSTKCILVGYDSNSNNYRLYDSERGNITIGRNVTFEEEAVEYVPVRVHSDCNSEEEDEDSGIGSTHVDEASDSETNNSMDTSEDNVAAESMDHSTSTSSSTTEKLITVKISANNKTYEAQIPENGEAPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWH8</accession>
    <name>A0A1D2MWH8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_09259</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000444">
        <property type="protein sequence ID" value="ODM97419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWH8"/>
    <dbReference type="STRING" id="48709.A0A1D2MWH8"/>
    <dbReference type="OMA" id="MLMMRID"/>
    <dbReference type="OrthoDB" id="242910at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="3"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1062"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1187"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM97419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1206" mass="134888" checksum="13F918164E796EBD" modified="2016-11-30" version="1">MELNFDANLGSTRFLKVCRAKQGPILWVVKVFVIHEHTVPIQAYCERLMNLKHSLSTTPSPNCLPFTKTISTEKSVIAIRPYVKFSLYDRMSTRPFIQWSEKLWIAFQLLCGLTQIHKHGLCHGDLKLENILITPGRRCCYVAPERFHDDKSRLGADNLLTQEDELKHFLLPSMDIFSAGCCLIELFTEGRVPFDLSQLLSFCSGEYDPSSVLQQIEDPNARELVAHMIQRDPSLRASADEYLTRFRRCLFPEVLYSTLQSYFDILAFQPLMKPDSRMVRLWQDIRNLPQDTTLGLIFTSLVTAEVRGLQSVTAKLYALDAFRMLLDKLSDESILERVVPYITFLLEDPTSPRVRAEALTALVDCLDYVKEVPPSDYNIFSGYIFPALEKLDRDVAVRISLAMNVARIAKISMRYLEASFLHDPERLDQQHPQFVSELHSQRDSIAGFLSNLLTDNDPVVKRVLVSTPGSLESLCTYFGPTKAHDILLSHLITFLNDKEDTHLRIAFFQCIPSVASFIGSHAAPLIIPLIKQGLSDVEEFVMREGLLTIKSLAEINFFRHRFLLDLLEEVLPFVIHPNLWLRHASVGVITSIKNNLSDVDVHCHIIPKLKAFLKLSSGSLYGVNEVSVLSKLIPPLDRQVYESCARAKGSLLASAIEYLRNTDGKVGEPDSVEVSNFIIRLKAEGLPIPLEPVYTSFLQKHIMKVNTQRCLRTTTTEISVFPVNSAKGSFGGFTQQQLQSHLLIMTTPPIKELDYRASVSTFSTNDGFVTHLSNSTMPRGIGTATFRNQQAPPQHHAVFTEKPRGILVAHLAEHSSSVIKITPLTTFKGLFATASRDDVRIWDAEKIEGRNVANRSRCNIRLPGEKTVNNITYAAGANIIGVADDQTLYGFSVENMVARCVFSLPIGTANEQLGIPIGLESHSPYLIIIGTELGAILGYDTRIATKEVFKYNSDLKCGLLTSLCSDEEHNWMCTGTSKGILNCWDLRFSIPVNTVKTDLPVRRMKPSPFHPWGVFTSCRSVNELSLWNLETGNRHISLWASPLPPLSKPPESSIPFRPTTSIHGITFSKNHNAVITAGSDFCVRWWDLDQADESFTLISPEKLEQQLTNSTFSKNGEFRFRLVDGVEVIHDLSVNSSVSGVNSGLHRKSEVDGSLGGSGRAPNTMAYSIMMGYAHHNVITDLSTVATPNQSFILSGSSDGVVKVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY50</accession>
    <name>A0A1D2MY50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxidasin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000400">
        <property type="protein sequence ID" value="ODM97861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY50"/>
    <dbReference type="STRING" id="48709.A0A1D2MY50"/>
    <dbReference type="OrthoDB" id="1574204at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="79" mass="8708" checksum="DEDFCE805481197C" modified="2016-11-30" version="1">MSRRKCVGVGGGNDNLLNATFALLVIFIVVVFTLDIGSSQEAPTHNQCPLRCLCFRTTVRCMFLHLEKVPDVPDDTTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYG2</accession>
    <name>A0A1D2MYG2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000419">
        <property type="protein sequence ID" value="ODM97695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYG2"/>
    <dbReference type="STRING" id="48709.A0A1D2MYG2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="563" mass="62403" checksum="65AD765C860ACD1D" modified="2016-11-30" version="1" fragment="single">MHRDDFEEVDPAVEGVQSYLEMVEARGKMQVKVKPRPVPFEEGAEFKLELNEEQPRSSVVTVEGPSQTITTTIEGDITGVTKMLDKMSMEDFEGLLAKIQAGGKELTPQQEAELIYDEFKDELEQDHRAPKEMAKPRRKKQQKKVRETVIKSEDAPGYQGTENDVDKLLEFIEGNQTKTKITEKRKKTEVKPKKNQKQTLQKAVVASSTGTSVKPKTTAEGGSNARAPEVNPIPVLALNQKQTPQKAEVNVKPESETIIEVKKEGGETKPVNLAVNPSSSPASSKDSKFVDEVKQSVSQIASITKYEDLKSEKGYESDDSYVLASNRKKNRHQCESVSVRPSSSTYQPHQDDSSHAQRRYTDLSKFGGPSRESRGITVTKSYVKIVRNPKKEGAKPRSTSIDSAPVATSKERHSSTPSRLEALDLHFPPLVSPSVEAPPAPKKTKNAEKKLLLKTEESLRMTVKSLVQRVQTLEQNVQGLMQSNKHGMSQKGQVNPQEPVVFCGINFNSAQTLAGRNTGFEFGFGVMKTLKDKGVAENPTTSEMIKRWNVKAATFVPATRAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYN7</accession>
    <name>A0A1D2MYN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein daughter of sevenless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000376">
        <property type="protein sequence ID" value="ODM98163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYN7"/>
    <dbReference type="STRING" id="48709.A0A1D2MYN7"/>
    <dbReference type="OMA" id="QANEMKG"/>
    <dbReference type="OrthoDB" id="67516at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046355">
        <property type="entry name" value="Gab1-4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45960">
        <property type="entry name" value="GRB2-ASSOCIATED-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45960:SF2">
        <property type="entry name" value="PROTEIN DAUGHTER OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="564" mass="62406" checksum="47FEB54076610FAD" modified="2016-11-30" version="1">MSSATKEVVHQGWLTKSPPTKAIFRPRWRRRWFIVKGGSFPHQFVLEYFTDESCRRQKGLINLDECEQVHTICGPLNVQDRHRYTFHLRTPSRIYYLASDTEQEMNKWVEVLCQVCGLKIVEDEADGNIVYARPSNENSKPLEVQSTDVHHESDDSSPTPSNKSPSGPYIPISECFTGKPIIFNPSGGNEEVTYYNMSSFPFPPKVNWATYPYKRDANEPVDESKTPHGQRSNDASYVPPRPPKKNSSKPTTPTSTTPSQTKPNSGRKSPDQVHSPTGHSAGIYENVDEVPDSSSTSSSLHSPPSSAGGLYCNISDTTESKTAGASVYQNPSASKPSTSPSPSSSSMSGNQGSAIPPKVDRNLKPEVKKANEINAALKNHQTPLASNAQSRLGCMTLPNKSSQNNFYSSGTHYPGPEIDRTRKPSDGNLTLGCTPAQLKYQSAMQNNSRNPNSSRMNTSTLPNQRRRAGPLISPHEKKTSSPIFHEYESTQDLIGTYMQIDCKTIKDSEPRPQALKLPPNKKLGVGPAPPGGSVEYKVIDHVKTKALNQMRMEREKQLETNPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYT9</accession>
    <name>A0A1D2MYT9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000373">
        <property type="protein sequence ID" value="ODM98217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYT9"/>
    <dbReference type="STRING" id="48709.A0A1D2MYT9"/>
    <dbReference type="OrthoDB" id="7742407at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048598">
        <property type="term" value="P:embryonic morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24381:SF393">
        <property type="entry name" value="CHROMATIN-LINKED ADAPTOR FOR MSL PROTEINS, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24381">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="506"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="583"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="231"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="596"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="607"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="623" mass="71967" checksum="0854F6BB3BC9097C" modified="2016-11-30" version="1">MVRDRNPALTKTCIVCRQKLAHQLNLNGYPGEEKGNDGNGKSISRWKALCAESLCMLFGLQDNHPLVTVFVNPNNICGKLCTTCLEDVSNVQHIFWQLHSMERKLDKLQTDILGRLRSNYEHVPVSTVFARMGAQDIVGNLHNLKYDEVVKILFETVKDSKDWPKPVYSPRWRKACDNAEKLTTISPVPEVNMDVDAGPSVGLVKTESHQETDGMFNISVDHDYYNPIAEADTQKVHDEEEPIDTSKIKSDHVKNDDDDDDDDDDDDHVLEDPLAGDYNDGGSDCDWENEKKVVPKKRGRVARKRSSLKKVRRKKAIKTEEEKTRYLCVEDPENCTRTYSARKHLKSHIQTFHRDRTHVCDYEGCTEKFVSEDKLLKHKDRVHEKVKKVKSVEICETCGVEVARGDMKRHFYMRHVGMGQYTCDRCSLDFNDAELFKQHELLHEQSEYPFSCVVCSHLFTNSLDLKTHVTSNHLSSGLKCSVCGIMKPNSFLLERHMKIHERTKRFVCDCGKSFASKGYLNYHLEHFHNNADKQYPCSVCGKSFRYMKNVLRHQITHRIAKICFNYSHLLKKHEEIHSGTKNYGCEQCGKRFRQEQNLTQHMKSHRPKSDKPGKKRSDNDQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYW3</accession>
    <name>A0A1D2MYW3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium-dependent phosphate transport protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08845</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Apical cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC34A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000406">
        <property type="protein sequence ID" value="ODM97835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYW3"/>
    <dbReference type="STRING" id="48709.A0A1D2MYW3"/>
    <dbReference type="OMA" id="FARTCCA"/>
    <dbReference type="OrthoDB" id="76259at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02690">
        <property type="entry name" value="Na_Pi_cotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="225" mass="24688" checksum="72553161E062C8A8" modified="2016-11-30" version="1">MGIGAIMTVLVQSSSVFTSAMTPLIAMGMISLERAYPLTLGSNLGTTTTAMLAALAAEGPNLKLSIQLALCHFLFNLTGILLFYPIPCTRFPIQMAAALGRVTAKYRWFAVCYLVSMFCILPLTVFSLSMLGPTAFYVVSIPIGISILLVILLNLLQNCKPHALPDQLRTWNFLPIWLRSLEPYDRIVNQVVQFFARTCCASCCKTAAPQQYQLQTVLVELGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1K7</accession>
    <name>A0A1D2N1K7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000311">
        <property type="protein sequence ID" value="ODM98924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1K7"/>
    <dbReference type="OMA" id="INECGRI"/>
    <dbReference type="OrthoDB" id="191150at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF9">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="246" mass="27799" checksum="6199903C8FEDD6F2" modified="2016-11-30" version="1" fragment="single">PQDYLNPRYEGVYAAAQPPAYNTGGIDPIGIPNMLQPLVFTDYLVIKQKKEWLEIACGCETKNKYEIHDQQAQLIYKAQENSDFLLRHWCGPLRPFILEIKDKDDKAVVALDRPFACQSPCCPCCLQKMAIFCPPGHLIGSIEQQNECLPELHIKDEQNVVVFIVKKPMFTNPCGCGEAAFPVYASDGINECGRIVKGRSDFFHEAFTDSDVFGIQFPPGVNPYLKILLMGATFLIDYMYFESTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N285</accession>
    <name>A0A1D2N285_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000287">
        <property type="protein sequence ID" value="ODM99331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N285"/>
    <dbReference type="OMA" id="CDCSSLC"/>
    <dbReference type="OrthoDB" id="6134459at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053231">
        <property type="entry name" value="GPCR_LN-TM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902">
        <property type="entry name" value="LATROPHILIN RECEPTOR-LIKE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902:SF1">
        <property type="entry name" value="LATROPHILIN RECEPTOR-LIKE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="39298" checksum="778D9916FAE3DF23" modified="2016-11-30" version="1" fragment="single">LRCDRNVCLFSFLVVVLTICVCFFVHRQGQGGSTGGYATCGFGARAEKQSTQLGHLGEFKDCGFPMEGCGDEEDPDFMVSPSYCRCDEACVLYGNCCVTVVKRLSEAPVNNTWRCVRLPGSDDGVRMIRRCPSNYADDFDNRRLCERPESECKENEDICPWVDLPVIHNATRHLYANIYCARCHGLRNEDLYRVREKKNCTKKFVGGWEAFKHRAEYAGGLEWRDPGDSDLNCSVRILELEIGAIRTFVVLPAGCGEGCDQFGDLGVANLCHAYMQVVNVRAVAYKNPHCAKCDLPGSASSGQCRRLPARQARDECGSEDTGNGAARFSDTRLLVSFLLGIQIRNKVYAVKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2A6</accession>
    <name>A0A1D2N2A6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase CYLD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000294">
        <property type="protein sequence ID" value="ODM99184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2A6"/>
    <dbReference type="STRING" id="48709.A0A1D2N2A6"/>
    <dbReference type="OMA" id="PALMLCM"/>
    <dbReference type="OrthoDB" id="6287070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11830">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="559"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1047" mass="118374" checksum="01754648F4DD9D00" modified="2016-11-30" version="1">MSSNGELRKGDKVFLHEKEAEGTIRSAVFKGKRLGENHELEILLEGHRKSYSEDEVSPYKLYLRDHLGTSLIPESDYVISRGVVQWEEPTWEVGQEIYYKPEKRWATILNRETNAKGRPLVAIKLDQTKFKKEKVAKVMLNDLMADSIALRAPQRIQNSNMNSESDEMMILKVNDAISTMDAVLSEQQSTNENEYKEKMVEKADDVDAQYSFIRKPSDAVPPPLPSVPPPPPQSKVTFEPTFMEMTSSSGKQEEEPIIALDEPPKVVARKKSKKRNKERPATEYIQESVSITLPAEDTNIYQEPEPLKFKSCNNINDTTPDDDVDQLELLNYTNSLRSSARKLIQRQLAQDSQSRSLKLKPTSSRPHVEEVFKWNNNSTNLNGTNKILDRPTFSYLNNYQPLKVTLKSTSSNDLSKSNSQSVVFREGPDGKIHPSPAESSIHKSQSDLSQPQPNQSNMMTQPQSNQVTMSQPQSNQVTMSQPQLNQNHMKQSHLHQPQLHRSHMNQNQLNRSQIMSQNQLIQSQLSQSQNPLEYNFLPLSSSELVKQQLAVTDRVLQNTKPSSDAVDRTSILRSRDDAKGVSSDSSSHDNDSGRGSYPFLAESPTRPSQRQSVTPTNGRRFEDESPTPSRSPMSSDSTGNGNATMANQNSINRRYTKNRSPTRNHLQKKPLSSNDEPPAADIHIPHPFNPGNLSPVAGYGRGIQGSLNSSFADATLYALFACSNIFDVNLLYSKPGQVERGIKKEIREILRQKIVTPLRMSAYCKAENVTHLREAMLPLSSKMHSSLMEADEFLYLLFDSALNTESFIQFSNGTKDFMHQILARPKDRSKSQTVQFMLETSLGTSELKFKGIPKPALMLCMPRCKGRLVYYEAIIPSLHLNITRLLQKGPKQCVCEMAATLECVVCHQQNGDMALDFCSVCKGIAEQIHFRLDHSPILVSKSQTDEILNLHSIICTRGNRYVAFVKVTPHRLSPWLFFDPLAGEFPEVTLLEDFGKWLDSLEKQPGHYREFSKLHPLLKRIMTDSHIYIYSKAHIVETPNYTESLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3D8</accession>
    <name>A0A1D2N3D8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microtubule-associated protein futsch</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000282">
        <property type="protein sequence ID" value="ODM99435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3D8"/>
    <dbReference type="STRING" id="48709.A0A1D2N3D8"/>
    <dbReference type="OrthoDB" id="5371837at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007409">
        <property type="term" value="P:axonogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016358">
        <property type="term" value="P:dendrite development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031114">
        <property type="term" value="P:regulation of microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026074">
        <property type="entry name" value="MAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13843:SF12">
        <property type="entry name" value="ATPASE F1_V1_A1 COMPLEX ALPHA_BETA SUBUNIT NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13843">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="35582" checksum="36B3619BDF199C1B" modified="2016-11-30" version="1">MGGEASSEDEKSQSQVTRTLIMTTDGGDKEKNRSLTTTTTTTRVISMTSDIGSMLPTTSTTTTDEEAYGSSSGDFSDQGTKDSPIITRTTRIQTVTKSSESGEPATQTTTVIRTRTESGGGVSSSGEEQGAAGGSDILKEWGKPLGLPTIYPTTNTSGDGASGAGSMPGSNGPDSGNFNARATPKKSQSSSGDKKEPGTPAKHGGAGASSSKKSSKKSKHSPIYVDLAYVPHHGNSHYCDSEFFRMIRGRYYVFSGLEPSREVFEGLLQGKQQWEDKNLDVTIIPTYDTDTLGYWVVDSEDALAEAKIDLAPSASRCTINLQDHETSCAAYRLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3E7</accession>
    <name>A0A1D2N3E7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000281">
        <property type="protein sequence ID" value="ODM99445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3E7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="648" mass="74425" checksum="228F6BB57136CBED" modified="2016-11-30" version="1">MASGGDALIGADPQTENEFQKEAVTEIFDSPWAYMPSPVFRQLISKMGSHFNPVARQVCISWLAYVDNEIGLSVKVDDTLPGNLEFVQSVKVAQARIVKWHGISMNMDSLPDCHSSLNNDFALFQFPTCLQKLTLTGKMPEQWTFRNLSQFPNLTHLVLRGASMHLQDMTGNPLPEPAFSPENPLSQNYQQYEPVVGPPVWMKKLAKLELIMNEFSYPSGLPLSVRLREPERALQHERHCQHLYHIVVNNATFILTNLRSNALKAAQLYIYPKAGIIPPTSINWRHLPLQKFLAHHRATLKELYLPEFEGKFDTTGVDIAGYSICLRKLQLELRKYIGDREQNFSQNSSYWQNLLMNQTRLVDLELSLADFPISWIDETLHSLAFSCKETLNFVDIAIEVADEPARINLELFTYCHNLEILKLSGKDHPLVAVNFCKLPESLKKIKLASSLLEIPDPEQIDKYTKLEMLELFTITILNGDHNLERTSQLALKLVQLRGLNYLSVSFDSPWCSGDSDIYTGLQSLDRDYMSVSVFCLKMNLIYELDHGWGDERFDIDKNQVECFNTREPEDYPTWHRNAISVDDEDHRLLIFHTLPFLLDLRERRRSQRFGDDEENNDADDDDSDSDDLETVVSNGSNLDFEDWDRETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3V2</accession>
    <name>A0A1D2N3V2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06772</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP = 3',5'-cyclic GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13665"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57746"/>
            <dbReference type="EC" id="4.6.1.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000247">
        <property type="protein sequence ID" value="ODM99901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3V2"/>
    <dbReference type="STRING" id="48709.A0A1D2N3V2"/>
    <dbReference type="OrthoDB" id="1890790at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF462">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="13040" checksum="1C9CE6D2D15B0C0F" modified="2016-11-30" version="1">MLSKEIVVKRCLSSDLQGDLVHLRKLAEPSDSFQLKAKAMTVLETIHGLRHENINALIGCLTDGIPALVWEYCSRGSLHDIIKQQDIKLDWAFKLSLLTDLVRVRKYCHLRVDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5Q4</accession>
    <name>A0A1D2N5Q4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RCC1 and BTB domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5Q4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="212"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="407" mass="46934" checksum="00618BA8D826E03A" modified="2016-11-30" version="1">MGVFLLEDASFTVSFNSSHQILQTSQVFHYVGEFRRQAYIKAIDDTPQSKNLVRVINSCVEADEAWLLRTRLIIDNRKKEGSMPYCNVVHAKVEGSFFPNLYRSLDSDLSIDVAIKLFRCGLDSAGKPNNTSLEIHIRDMNYFDGRWARGSARMVTWRPYLESYFAPKRSQRINGTITIQAFPRSYIILPINSRPFLDTPGFGFNIDDADTKDFKLKGNDGIEVWCHKKLLEGCCKLFATLLSDDRWAAGQNNEYTFQDYSGPILEAFVQYMYTSSTAAPSRHPAIALGLLELAHVYEVDGLESLMIAVLQGQPWIWFDVLTAWSVYVLSTQRLTFRDNQHDYRGLKEKARGVIQTFLRRSFVVRNESRYRLRNREESEETIIFKEEVKKNRQAFAVQFNVDPNSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6K9</accession>
    <name>A0A1D2N6K9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Compound eye opsin BCRH1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05780</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000182">
        <property type="protein sequence ID" value="ODN00900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6K9"/>
    <dbReference type="STRING" id="48709.A0A1D2N6K9"/>
    <dbReference type="OrthoDB" id="2101615at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0844">Vision</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905124" evidence="11">
        <location>
            <begin position="22"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="1"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1014" mass="112837" checksum="F96B1F67039C3BAB" modified="2016-11-30" version="1">MFVCVLIWVLSLGLVIPPFVGWSKYVIEGVGTSCSWDYTSRDFRNRVYYIFLLTFGFFVPVSIIIISYFGILQVVCKQSSRMNGFSRNGGISKKSPTRSDMKTAQKSAVLVAIIFLGTSHGQKCQEGNSIVDLMFVVDRTPNPDKLASHPGGLLNDVQVSLQNRFPGSRFGLTLFSDFTNSQKGDPAGDTDDDKSEQSNYCYRLKSSLKERLDYQNAFKGIKKGPDGGKGQESVLTGILYTAADKSVGWSKINYNKKAQRVIKLLAFITGSESLSDQVHNLPNKPTPKGDGKDDCDNFGLPSTETINSILNKKQMGILGILTNETVIPYWEKELKSLTNVHQETQKLTISDKFDPSYAAQTDELTEKIVSLIGQYNCFLDPPGKSTVILSIIVCFLVSWTPYAICSMIGQFGDASLLSPLATALPAIFAKSSVIYNPFVYGLSHPLFRTAFATLKAKYLGKRNAGGITANPRLHHHCPYCHNKHPSRKIKLVVTARGDGTYNTTYDHRHRFHLDGQKMQAEGFRGKIPKHLRRHFAGNAECGERAGRCSNEDKSSDPQTPLCQRSKDCTMEQGMTLSTMQTTPCNSVKGRKNLRNLKKGVWIFKNANECQPSGSDATARTAVNTCNESSDGGELETSLSIRRNPYAVHSNGDGRSMKNSYTFFMCEYRKRRQDAIQHIFFQSENCLNDLFTERAGSNAPKSHLSTSLGQGVRMSTCTHDGESKCEQCESSFETVKKAASYHSIDNRVISEFGAGIHTNNLNLREDPNPKRLFEQTRHSICCAPTVVNSDVRRHEFSLVCFNRHDKEGKTVGEQLKNQNGTFRENYKKVRQDLSSCQYQREKEGKGNANTMLRRNLYQTKTYLSAGDMEKAARDMIGMSNGMSNVGKKKEIFQRLRKSVSLSGLKVTAVESGLPLQTTVCMANPAISEFALNDLNEPKESTKTRMSEITSFRGLEIDSGSCSWCHCHNNSDSPFSSADEQSRHEDIDPLQCSGSLYASCNSDLCSLEDKLTVNYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Z7</accession>
    <name>A0A1D2N6Z7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E3 ubiquitin-protein ligase PPP1R11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Protein phosphatase 1 regulatory subunit 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05624</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Z7"/>
    <dbReference type="STRING" id="48709.A0A1D2N6Z7"/>
    <dbReference type="OMA" id="PREEGCG"/>
    <dbReference type="OrthoDB" id="307488at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00031039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="101" mass="11109" checksum="EA05E29E28BE5C79" modified="2016-11-30" version="1">MAGTETSVVTTSQTTIEARPEVQESSSTVRLVLRKPKNKKKVVWTEETVDNENMNKRKSKCCCIYKKPHIFGESSSESEDDCENCHGHGPPPPPPAAPPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N709</accession>
    <name>A0A1D2N709_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="23">AFG3-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_05938</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000188">
        <property type="protein sequence ID" value="ODN00746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N709"/>
    <dbReference type="STRING" id="48709.A0A1D2N709"/>
    <dbReference type="OMA" id="INWFQEL"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005745">
        <property type="term" value="C:m-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000019">
        <property type="entry name" value="AFG3-like AAA ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000003">
        <property type="entry name" value="AFG3-like AAA ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1690.20:FF:000001">
        <property type="entry name" value="AFG3-like AAA ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050928">
        <property type="entry name" value="ATP-dep_Zn_Metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655:SF2">
        <property type="entry name" value="AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="22">
        <location>
            <begin position="343"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="60"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODN00746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="698" mass="76137" checksum="0DB70675C84E375B" modified="2016-11-30" version="1">MAYRLINSMRSVNRLVKVGGPGSGSRQFSIKVLTRRYPDIEKLLSEFRVYFTDKPPKGFEKYFKPKPGEKSVKPPEGKRAEAKGEEARKPSASEMPSTGAAKGSGSSPRPPGDPWSSFLGGGGPRLGGGGKGPGSTGLGGEGGDKMIFMAVVGTIVLLGTFAYYEMSYTEITWKDFVNIYLAKNLVEKLEVVNKKWVRVRLGPGAFSEGVLWFNIGSVDSFERNLENSQMEMNIEPSNFIPVIYKTEIEAASLTGILPTLLIIGFLIYMMRRSAEMMGGGKAGRRGGGIFGSVMESTAKLINSSDIGIRFKDVAGCEEAKVEIMEFVNFLKNPGQYQELGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPSRVRDMFTMARKHAPCILFIDEIDAVGRKRGGRSFGGHSEQENTLNQLLVEMDGFNTTTNVVVLAATNRIDILDGALLRPGRFDRQIFVPAPDIKGRASIFKVHLKPLKSDVNKDDLARKMAALTPGFTGADIANVCNEAALIAARDLNTSITLKHFEQAIERVVAGMEKKTNVLQPDEKKTVAYHEAGHAVAGWFLEHADPLLKVSIIPRGKGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEQIFFSKITTGAQDDLKKVTQSAYAQIVHYGMNDKVGNVSFDMPQPGDMVIDKPYSEETAQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8B7</accession>
    <name>A0A1D2N8B7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Synaptotagmin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05196</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000149">
        <property type="protein sequence ID" value="ODN01498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8B7"/>
    <dbReference type="STRING" id="48709.A0A1D2N8B7"/>
    <dbReference type="OMA" id="WCDIEKT"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017156">
        <property type="term" value="P:calcium-ion regulated exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00276">
        <property type="entry name" value="C2B_Synaptotagmin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000179">
        <property type="entry name" value="synaptotagmin-5 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001565">
        <property type="entry name" value="Synaptotagmin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF378">
        <property type="entry name" value="SYNAPTOTAGMIN BETA, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00399">
        <property type="entry name" value="SYNAPTOTAGMN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="94"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="225"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="363" mass="40491" checksum="4BB4B13D6B785BD7" modified="2016-11-30" version="1" fragment="single">RASRCLSPLLIPPMSPSPKSPTSLAGDGPSSGPVTGPLSPLLGSLQLDLYQKQDICIFLDASKQPSGYRPPPGNKSAPADATDVATYNAHHNIPLGRLHFGIKYDLDKSDLHVTVIEARDLPGADQSGFNDPYIRIFLTPEVDTRKRETNVRPNEANPYFDEQFKFPVSQEDLTEKIITLQVLDKDKYSRNDIVGQVSMRLEDYNVTTNMDVWAEIVQSRRPSGEKQEILISLSYLPSAERLTVVLLKARNLHPPPNKDTIDPFVKVYLLGGGKRQRKKKTTARKNSNNPNWNEAVTFSISSTALPSASIEICVLDQSYDLMGRRSLIGACMIGPHQNGSELSHWQETNQNFRQTITMWHVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8E2</accession>
    <name>A0A1D2N8E2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MICOS complex subunit MIC10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05151</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Mitochondrion inner membrane</location>
            <topology evidence="2 9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the MICOS complex subunit Mic10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000148">
        <property type="protein sequence ID" value="ODN01522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8E2"/>
    <dbReference type="STRING" id="48709.A0A1D2N8E2"/>
    <dbReference type="OMA" id="SNCRHDL"/>
    <dbReference type="OrthoDB" id="1916310at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007512">
        <property type="entry name" value="Mic10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304:SF0">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04418">
        <property type="entry name" value="DUF543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="83" mass="8924" checksum="F59E0EC0EC8DC3A4" modified="2016-11-30" version="1">MPAKQVQLQCEDQIPSALDKCIADTIIKVGSGIVAGGALSLVLFRRRLWPVTLGIGIGTGMAMANCQSKLNSTDVVRRNLERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8P6</accession>
    <name>A0A1D2N8P6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein SET</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05094</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8P6"/>
    <dbReference type="STRING" id="48709.A0A1D2N8P6"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="294" mass="33510" checksum="12E537E28D952041" modified="2016-11-30" version="1">MSGDGPSPPKILRVEENPSRESVSKEVGAAPLIPVNVIPEAGAHKQDQATDQDIMLALDDLEDAQIEFIRVVGDDEYDEDVSMEERATVIALRAATIKRIPNFWRTVFVNLQDGSSRFKIPEKEMEPLSYLTGFKKVHRADGFRFTFRFNPNPYFQNEVIQKTFRLVGGTPYGSTIESSTSTPILWTGEDLSRWEGIPCCNNCQEEHWPGFFEWLANDSDTDQYNELSETVSEHLWINPIPYYQNVVVDTANPYNIVRAENEEDEDDPAPEKSRIIYAIPVTFWDLKKNSQNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8R3</accession>
    <name>A0A1D2N8R3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS-type transporter SLC18B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05033</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000145">
        <property type="protein sequence ID" value="ODN01642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8R3"/>
    <dbReference type="STRING" id="48709.A0A1D2N8R3"/>
    <dbReference type="OMA" id="REMACIC"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17385">
        <property type="entry name" value="MFS_SLC18B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF28">
        <property type="entry name" value="MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="132"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="535"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="657" mass="70672" checksum="DD3A269DA334F8CD" modified="2016-11-30" version="1">MSDNGKRNNYGSTDSNVGVAKENGGGGSGSDDGSDIFCINDIVIPFSDDCCYMQQIREQSGVTNGPVMVNYQYARSRRRPVLVRTKSESDFQALLDEDVQQIRDRLVRRYGKPHGTFALKKLPSLTSQQWIVLATLAIVEFTCFCTMSILAPFFPSEASAKGVPTSISGFVFSIYALVIFLTSPLMGIIVGHVGAKFLLILGVLMGGCCNILFGVLGYVQSTGVFLGYCFLVRIFEACGAAAFSTASYTIVAEVFPDNVGVILGVLETFVGLGLSCGPAVGGFLYDYGGYGLPFYTLGCLMLSTIPLSMFAFPRSVFDANPSQKHGGMLKLLKIPSIVVLCLVIVVVSNAWSLLDPTLEPHLRQFNLSAKQLGLFFLLLSATYAISSPFWGWLADKMERTWIMMVVGLIISGLGLFLLGPSPFLPLSNNIPVNIVALFILGASIGMTLLPTFEALLDTAFDAGYPDEASTYGLIAGLWSGAYSLGEVIGPSMGGFLLDHYGFPICTTVNAALCILLGIFVLIFYCSASGNNYDMECDSRTNPRSKTTTEVSDSGISDNPGLSSSQSSSSLNGNKYLLDSNEGIAAHEKTPLLLPNHLDQKTSNLIVSSVQAHNMEASCPVDIYSDDDYIEESCIQTRESFPDVLKTVCFTGQGAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8T3</accession>
    <name>A0A1D2N8T3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sin3 histone deacetylase corepressor complex component SDS3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05017</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000144">
        <property type="protein sequence ID" value="ODN01662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8T3"/>
    <dbReference type="STRING" id="48709.A0A1D2N8T3"/>
    <dbReference type="OrthoDB" id="70376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21964">
        <property type="entry name" value="BREAST CANCER METASTASIS-SUPPRESSOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="28"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="30564" checksum="BD803780A82DE417" modified="2016-11-30" version="1">MVSIMSPRTRTLSDSMDYDDELAELHDRRQSYEMDRIERPFRCSSPSDTRYNDHKLNESDEDTEDASEDGDVRQQDEHQEIKEQSRLNEACRDYELECIEREYTNERLLAAREFEDKKIELRESLVNDLEEKKKHVEQERFSMELTSDPTEVKPMSTRKLRRRPNEPVPIPEKRRKTPQSQITFLLDDKEVDEDLKSLLKRNFKDSVYSKSKNGSGNSEGADGNPTPQTPVWVRKLNEQTKIKVPISALQKGKMVIKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N992</accession>
    <name>A0A1D2N992_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 13D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N992"/>
    <dbReference type="OMA" id="WANQETI"/>
    <dbReference type="OrthoDB" id="272810at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF141">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="725"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="774"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1084"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1196"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1093"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1818" mass="203789" checksum="1FE48B76EFECDA7B" modified="2016-11-30" version="1">MWETFISWYINTYLGQYVENLNSQQLSFALGQGELELENVPLKKNIFRSWGLPVEVKSSVVGRIKIEFNLFKYLRNEPVLISIEDVYVVAGPLNLSEWDPVEEELIAHDAKMDSLDSYEARWKAQFDISSNESSYYSSLYFSSMRIGASIVTKVVENLQLNVRNVHIRFEEASGIPGRVIAFGLTLEGLTAQSCDSSWNTLSSSTGSTSECSFKTLQLNKFGIYCDTRGEPYSNLGPADLKIHMSKTLVINHEYLLCPVSAETRIAKNNSTTSLSSSSKPRFDVHLVLDKVPLQLTDSQYRNTLRTYKSFMRLQRHCRLRHYRPFGTVKDNVADWWLYGIRAVLTLKGYKRRRQLKTLEEVLQRARDNVAYVKAYEEHLTGELVSLEARQLKDRVESELHYDEIIELREIVMLRMEKRGYVGEIASTPLKEKTSASEPVPLETSSQTSADTNVQQSRYGIMSWLFPSWTVQPSDAGNLKTTENTQQLALPSTPSEGLASPNVRQSESDLDEAILGDVKAFGRDALLARFSFKLDKGVVSLMKKSLPFLEFDFTGVHVDASLRPRTGSHKFQMTLSTVSLKDCRTKQLIVTPHHIPGGKYPQHLPSLSPRPKEAGFKESLFSLIYEKKPHKKAGHKISMTTRPLDLILNPELYDDLQKFFHIKDIDEDLNIHQSRYEMMKQKTKEEFRIYWERLVDQQTTSNTYGVSNWEIYLDISAPQIIIFGYKPPAERPRHPNVRSQTRSESRHQINAKASSASGGSFVVIDLGRFRFTNVKNDDGIASPEPSISNRDNETENSLTDDEDEEFMTPCSSPLPEPQESSYTSPGPSIVGNSDDLRRISLDNGIPGDTLENFYSKLYKNYSLEITDIHVIVVDARSSRDVNWRAASCKNTSSMHLVDKFSVDVQLERRLVYSEDPMWPALTVIATLPKLTFHVNESKVNTVRSVIGAYFATKSSQMNESRADLSFLNQSVTNIPEVDPGVAAQSEKDVLTDKLQRESRRSSSRLLVAQFTVQHVSVDIQSRDRNIAELQILGTRTIVSKRSENTEITFVIQSLLLADAVQTFGPDFQLLLASHKHVCMDTVSGSLRDSEPTSPMSPQPPASPLPHMSAKMAASLTMPSQLHEALLASLRSKWKKQTHCLDSHNTLLETDALITADLTLTHKDEDMAILHVQFNNLDVIANQETWVEIFQFIQKLTPQSSEDMKHDNDAEIPQPDDPEDMQKSSQKLQANFEFRRLNVLLLRGVVGKDGDEGARKIATATASDSKINLVLNKGMLTAEGSLGGLQMLNLTPEGHHHQRVLSVGQDPLIDPTYQPFVLGEELPTLPGSNESALTFHYEKNVTKHHSNSAPKLVLRMASVIYTHCPVFLVDLKKCISQFQEPLTTKLKSAAAQIALGLVRQDAIHSLNFRSSSNSLSGSLERLDFEEEHILNYQEASKSSKTSLRLDIVLDSPVIVLPRNRSSPEVLVANLGQINIVGNNQIEGSILFPHSTALDLDEKYDDDAIKYNIFVCDISLYSLNLTDRWKMVDSLKMTYPSANSTTLMRAQELYQCDHPSAIPILHNTVIHLTVSYIDECSPGGQAANGEYGDTPDFHGTSSQLHIQGRVISALKVSLTPKQYAQVLDSLGNIASNDEDLDKNEVSVTERRVNWQKEVGHLKGRMKEPLPLPSPTHYADDSLPIKSAFEISELIVELALPVQAHVLPRSDGVDIPHLSLSCSELTFHCDKKSHRMEMDICLKALKLEDTSVTVDSPRRLLASSKPGSQQPAEPKLATAAARHSGSGHISKSCPDLQATQPVLIKERGEPIEISHGRSYRICISSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9U6</accession>
    <name>A0A1D2N9U6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sentrin-specific protease 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000140">
        <property type="protein sequence ID" value="ODN01756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9U6"/>
    <dbReference type="OrthoDB" id="8188607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="4">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN01756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="121" mass="14225" checksum="C2320814749D6B51" modified="2016-11-30" version="1" fragment="single">YDFQAVLDFVRMEATARKQIDLLNSLDTWRVLTEERWPRQNNINDCGIFLCLYAEALSLRAPPIFNTKFMNLQRVKIMIELLQSSLEEPNYDLSYYVNDAKKILKQGSRQLGWMPGVTYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA01</accession>
    <name>A0A1D2NA01_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA01"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="65" mass="7789" checksum="3B09B47C0C2CD5DE" modified="2016-11-30" version="1">MHTTQYFILTKFTRNYEWVKLLLVLVAGLATMMLPTVSFLRRRKQDIRWKMLTGFRLQLSPGWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA96</accession>
    <name>A0A1D2NA96_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000122">
        <property type="protein sequence ID" value="ODN02178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA96"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905285" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="26805" checksum="926C763F9AC7CCAA" modified="2016-11-30" version="1">MNQLLTVSVGVLSLITLTVAGTSYNYLDEKQDNSNINFNQPFDASYYLEMSCPKKLPIDRLIVRRAEACLEKTLNDEIVAKLLIMASVREFQKFSTKICKQWPHIRICLDEIISYLESCHEKSYIGQVTDEIVNYVCTDPISDNVDTNNLGDFLTAGGLSCTNFDVLASCMKFSLDQSISFCTMTEKIRSCSKPAFDGCDTSKPWDVIEKGLGEQEAIMRCGTPEENGVSSAAPSLNSINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAM0</accession>
    <name>A0A1D2NAM0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAM0"/>
    <dbReference type="OrthoDB" id="10617133at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF58">
        <property type="entry name" value="CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="544" mass="63274" checksum="32AA2F4C76672539" modified="2016-11-30" version="1">MSNPGEISILSKWLQGKLTEYFVKKSRNQNSKNWSSTDFTSASKPTNRPPIEVPFFDFRILELQLETDQDDHNDETTQQKSSYYPTSTGLFDVVHDEVLRPPCKTEQEPYKQGNSHVYLVYQKGCQSVGRELLLHMYAAEIDDMDLVGYVPKFILSLDEHQIDVYTRVFPLLKAWAKSHDVVVNFSVPECFYGCYQTEEKRQLIENLELADDIFLDGIMNKVAAGIKYYEREKRNERPVKQSSYRLLILDDICRQGYEMKSVPGITFLPLLNVEEALKRMAEIHSTSWAFCEMTGKSFSKTWPFLTHPLYLPYIRERIIPGYFSMVEMVHDYLVKGGRDQVEKKRIMKRLVKLRVRLDEILERSHHPRTVKCLIHQNACSSSLFFRYSYHQEMKQKKDEEEIKVKINSSSGGGDGDEYLPKARRDCLQRRLKREVMITNWRTASFGSPMIDVAFLLLTGLPPKTRQAETGSLLKIYWNAFRAHAKLFGLSVEWSDQQLYEEYLECLLYTCVLITGNIRNQGKLEDNEMEAFIEAIKDLIDLGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAU8</accession>
    <name>A0A1D2NAU8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box/LRR-repeat protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000114">
        <property type="protein sequence ID" value="ODN02379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAU8"/>
    <dbReference type="STRING" id="48709.A0A1D2NAU8"/>
    <dbReference type="OMA" id="DIHECEN"/>
    <dbReference type="OrthoDB" id="8251722at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="678" mass="75980" checksum="824976810F374AC5" modified="2016-11-30" version="1">MSSTSDNGYDSELENMEGAEGGGENEGPIVEVVNNEGSSNMNPLLFPDVISGVLSHLSASEVESCRLVSRLWNIEACKVLKNKRIVVFMDGDAIKVYNNAMKDTTLFPHAQFEICTDLSNEHFAEFWSIFGTQIKSLDLRISSLSWRDFLEVVESNVPNLEKLSLRFLPRQEPRGKIDLESKAPIRSVKQLRLASIPIAMNGSHGAIERLTGLLKLLPNLEVIELLRIKQVCMQSRVSQSLVEVLRKPEVNLPFLKKLNVNLVGITSEVLESLALKRLPLERVEMGLVEGVKATSYKDFLLSLRSTLTHLKISYPETFSNYQPFLEMNDAMKPEECVQVLTKLKSLNMINFKGSINFIHKMPGLTKLIYATNNLKDSIPLGLRRMPYVGHIEDHSLHALKITSPNCPADTISLDAISRCFPYLKSLDLHHVDDEGLGVIYRGLPLLSVLKLISSSCSDQGLTGIPLEICNDMVETGIFTVPTVDLYRRDLYIGSLPFLRTLAVSSPKISDASIAFGVVACKNLKELQIGSPLISDKAIIFLSNRVCKDMDVLDISKCSKLTEQSTFYAHEKLVGKVIVPVSTEGEEQGEPSRAASKKKTLKLQLELEKSDRGMVKMKRGSSASASRMSSPDTLFFEEIETEHYPPFPFQDANRRRNVRIRVHAFRRFDNPFRGRHHMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB02</accession>
    <name>A0A1D2NB02_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein lethal(2)essential for life</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB02"/>
    <dbReference type="STRING" id="48709.A0A1D2NB02"/>
    <dbReference type="OMA" id="QRSERHV"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF13">
        <property type="entry name" value="HEAT SHOCK PROTEIN 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00299">
        <property type="entry name" value="ACRYSTALLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="46"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="23075" checksum="582853F4F6D91BBF" modified="2016-11-30" version="1">MAIVFERDPWGWVHPFYRRRPMLSDWDDFFLPTPKMNTMGSMKPLMEHGPPFTPWIINRGLEGTDKFEIKIEVQQFAPSELDVKIVNNFLVIEGKHEEKRDEHGFVSRHFLRKYSIPPDVKPETINCDLSSDGILQISAPKMSEEKNRNEKVIPITYTGQPALPLQQRDRSQQLKVVERLRSVKKLTQREKCSGGNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB05</accession>
    <name>A0A1D2NB05_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pancreatic triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB05"/>
    <dbReference type="OMA" id="SKIWACK"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF173">
        <property type="entry name" value="LIPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Lipase" evidence="5">
        <location>
            <begin position="26"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="37925" checksum="237279F6A61CA17D" modified="2016-11-30" version="1">MFVNPIAVAIGVITCFPLILALPTFDSVRFFLYPDPWNLDYTQEIIPGDSKSLLTSKYNKWHFPVILIHGYGQNYSTSFPQLTKDAFLKQKLPVNVIVADWSGIIQKLNVVVNRRHGIHGPLTTVNADLIGKRVGEFIVFLINHGVLTDPTRVHLVGFSLGAQISGIAGQHAKHYTGRPIQRITGLDPAGPLFHFHAIKGKRLDHSDAYFVDVVHSNQGRYGIAGNNGHVDFFPNGGGPEQPGCTPRSDIPGLPGSCPHVRAWEYFTETILGSKIWACKAISYKDYNVLGNGNCHDKILFGLKVPPTARGSYYFDIVRNDPGSPAKISGPSFASYGLAPSPLYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCH0</accession>
    <name>A0A1D2NCH0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03730</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000091">
        <property type="protein sequence ID" value="ODN02957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCH0"/>
    <dbReference type="STRING" id="48709.A0A1D2NCH0"/>
    <dbReference type="OMA" id="GSNWGVW"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="9">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN02957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="623" mass="70361" checksum="FDDDC2ECE5B9A6DB" modified="2016-11-30" version="1">MRTGTPWIRILDFLVVNLSTIYMINYYMELQMDQVKMRYESAQDTYDFVIVGAGSAGCVLANKLSEKHTVLLLEAGGDHHQPLINAPVLFFNNQNRFPHDWQYKTVPQVNSSFAFKNNVTLWPAGKGLGGSGLINGMIYIRGSVQGFDDVAERTSNPIWTMRNAQKHYKQLEDYHGHFDQKNHGVGGGMTIEKGDIRPVIDHVMKAGEEMGYKVRDPNLDGPITEGFAPMDFHMKNGYRWDSYKAYIEPILDRETLTVRKFAFVNKVLFTGENNKAVGIEYERHGQTKIAKATKEVILSAGAIQSPRILMHSGVGPKSHLEEFGIKPILDLPVGENLQDKYGAFVGPFFVDEGKSFLMERELTMARMVEFGIFGTSPYASTRLEGTYTFRSSKAKTEGYKYPDIFTYIMVHSTDSEYERDMEIAANTKKEILRGYYKMWAGNDSFFQLVTLPKPYSKGFLKLRDADPKSPPVLDPKYLSHQRDVDLLVEGIKFAVKLVEETKSFKEIHGKMLPVSFPGCEKLPFKSDAYWECVARHTTATAYKYCATVPMGKDTNDPTAVVDSFLRVFGTKGLRVVDGSVFQEKEVSVNQCTCQMLGSVASEFILDYWDNQASGLDNSLDDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCT8</accession>
    <name>A0A1D2NCT8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">High mobility group protein B4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03639</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000088">
        <property type="protein sequence ID" value="ODN03062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCT8"/>
    <dbReference type="OrthoDB" id="498543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="36"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="106"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="36"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="106"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="24495" checksum="9D539B5424A2B99F" modified="2016-11-30" version="1">MANPSVNLMENITDRDVFNRLSEKEKWKQLRNIKKPKRPLNGYTRFVTDFMNRNKDKRGHKKMTDAAQAWKNLSDDQRNVWEESSIVAKATYSREVAVYNRARKATKKPPSAFALFVKNRWKAEKKKQYPDGKRPKFKVIHKQIVKDWKKLSEKERRTYFSTADRLLTLFKKERKAVINGEKDFNLFWGGDAMENYHEDEAGDMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCW7</accession>
    <name>A0A1D2NCW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000087">
        <property type="protein sequence ID" value="ODN03103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCW7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="366" mass="42710" checksum="BB2088162C206429" modified="2016-11-30" version="1">MESTLVNDISEDEIIPIEPYEYNGNEFFQQLHDNGTLWVPSEQKMIEDEKLQGKIKRAKLRLLQKRKEEEAEAKILRILNNADNTKSQGQVEVGDENMLTGGGGEEFDDEEEEDEEEEDEMLNSALRLGKPLTKALSKKEMLVDRIKDKTKQTVANIQEKIKRSKLKDLEHEARLDVLRQENEKSYLDSTDYEKFAIIDKFAERVKQRNVDEIFQRPDFSESEKNVDKAPGEKQKPYELLYAKEPEDKENVDINEDALFRKMRHVYDITKNHPYQHYEEYCDDLIREHVDNAKDCDTLLNQGLELVFMYERQQLTADDHVNKRVDMNAVDDDDEGDDASDKANRLSSSKQPGPNKLQTVDEEDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCW9</accession>
    <name>A0A1D2NCW9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Folate receptor beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folate receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000092">
        <property type="protein sequence ID" value="ODN02925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCW9"/>
    <dbReference type="STRING" id="48709.A0A1D2NCW9"/>
    <dbReference type="OMA" id="KDDFTCK"/>
    <dbReference type="OrthoDB" id="567542at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004269">
        <property type="entry name" value="Folate_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018143">
        <property type="entry name" value="Folate_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10517">
        <property type="entry name" value="FOLATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10517:SF14">
        <property type="entry name" value="FOLATE RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03024">
        <property type="entry name" value="Folate_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905372" evidence="4">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Folate receptor-like" evidence="5">
        <location>
            <begin position="33"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="30569" checksum="9024A9919A5A5202" modified="2016-11-30" version="1">MASRTFGVIFVIFCALPYLTASDSDELDELTNTCMDARNHKSKPGPEDSLHAQCSPWFNRSCCTTKTSIMTHTQNMYNFQWSHCSQVAPLSEKCLKHFRQDLCFYECSPNVGPWLVKVDMKIRKQRFINVPLCKSDCTAWFRDCSDDYTCTDNWGINFEWTKYGNRCPTGSICKKFREIYSNNATHFCETVWDHSWKVVEDNEHCMRLWFNPENGNPNDAVARWEAENIIAQKMQMSGAISFQKMKPLLEIIVPLIFAIYLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDR7</accession>
    <name>A0A1D2NDR7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein argonaute-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000075">
        <property type="protein sequence ID" value="ODN03404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDR7"/>
    <dbReference type="STRING" id="48709.A0A1D2NDR7"/>
    <dbReference type="OMA" id="CHIPPTH"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="127" mass="14769" checksum="8410AE823D9D0C8C" modified="2016-11-30" version="1">MERYFAQIINAPAGTVVDQEIVHQTHNDFYLLSHKGMLGTSRPTHYRVLWDDSDFTADEIQHLTYFLCYMYVRCRKSVKIPAPTYYAHWAAARAKALADGMEQQFTSTKDLTQYMSRTPELAPMHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDT5</accession>
    <name>A0A1D2NDT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000080">
        <property type="protein sequence ID" value="ODN03255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDT5"/>
    <dbReference type="STRING" id="48709.A0A1D2NDT5"/>
    <dbReference type="OMA" id="WIHILAS"/>
    <dbReference type="OrthoDB" id="7468414at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF3">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905417" evidence="2">
        <location>
            <begin position="26"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="711" mass="77905" checksum="520F112D7BB38908" modified="2016-11-30" version="1">MNSLETWRALMLGAALTFCISQVQSLPVYPYPSPGPTPGFYVPTIDPYSVPYQSVDPYAVPYPSVDPYAVPYPSVDPYAVPYPSVDPYGLPQQQQSIYGLPYGQPTPSPVYVPTVDAYYQAPPSPSPYPSVDSPYNVPQQQNYALAPSIPQIPAQIPYQSQVVVEEDIYQAITYHEMGEAKHCGVVSATNDALYTGAVPGGINDVVPYGSIPWNLLIVDNDDNNVVCLGSRLHTGLTLTHSSCINGPASKYSVVHDWDILTIYNEYEPYKSVSSSVCSIWPVGIDNSSQPVQYMLGGPYSELTLLITSDLPSDDKYPAFDWLCLPSKSSNLPVPSPYNQPYGYPQPSPYTPYPQIAYSSPDYGYPPSNAECWVAGYRSSPTAILQNHPLPTPAANQPPNPYQQQYYNILDNSKVPRKALVRQVQCPSGYPSPGYLPYDDVCFVGVVGYDACVADKGAAIFCVVGEDAEYDSGFANDQSSNLGSIPAGSSAPSQPNQQQQPQQQIQAQAAPPKEGRKRAVLYAVVKAPTSCYSPQQPAPYQGNQQQSNYVVATRVSPDIRGAIVDLQWQAAYVFSCPAEKVQDVIPRLGTSSLPPGVPVPQVQYPSALLQPSLYDSSLIYDPSQQYQPPPPYQQQPVQVPSYQQQPVPQYQPQPAPVYQQQQVPVSSYPQPSMLLPSYQYSDPVSYSPVYNPYPQQGPILQQQYPIDLYGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEB5</accession>
    <name>A0A1D2NEB5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase</fullName>
            <ecNumber evidence="11">2.4.2.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_03090</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1-&gt;3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:56064"/>
            <dbReference type="Rhea" id="RHEA-COMP:14610"/>
            <dbReference type="Rhea" id="RHEA-COMP:14611"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:140575"/>
            <dbReference type="ChEBI" id="CHEBI:140576"/>
            <dbReference type="EC" id="2.4.2.42"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.42" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEB5"/>
    <dbReference type="OrthoDB" id="6238971at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140563">
        <property type="term" value="F:UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016266">
        <property type="term" value="P:protein O-linked glycosylation via N-acetyl-galactosamine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051993">
        <property type="entry name" value="Glycosyltransferase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46012">
        <property type="entry name" value="IP22168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46012:SF2">
        <property type="entry name" value="IP22168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN03601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="442" mass="50367" checksum="6877695C9D2884A7" modified="2016-11-30" version="1">MWYSSDNEKSDQNPKAEGLVAPSATPSLQSLFKIPKRKFTHPTTTASPTPVVFKKCPVTVAIILCEDDRYLSITKTNHTVSVTNGTARNYQYSTGKPAIAKNFSRQINQTIVLLKSIAILSKFQVAHPQQLSSSCVEILLLSDKPTHYKAISREIKSKWSVEFQQLFKITHVPVRYPHGSAWMRKLFRPCATLRLFLAELLPDHDSAIYVDTDVIFFQSVQALWAQFGRFNNSHDHDNTAFENKTKKIAAMAPCLFHYGSSANSVPYFGSSGLNAGIMLMNLTGMRMTQWTNKIRMVTTMFQDKIKLADQDILNIYFHFFPEELHMLSCDWNFRPFQCRKGSYCADAQLSHGISALHGNALSFTSQGPEPLFRAIYQVFHWTKLDSNFSIVEFVDRLETTLLKVEETTHNSDCKRYGGFNVVALNRYYNIVERIEQDRIGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEQ2</accession>
    <name>A0A1D2NEQ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EF-hand calcium-binding domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000073">
        <property type="protein sequence ID" value="ODN03456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEQ2"/>
    <dbReference type="STRING" id="48709.A0A1D2NEQ2"/>
    <dbReference type="OMA" id="DNDGCVS"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF60">
        <property type="entry name" value="CALAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="251" mass="28470" checksum="FEBD0CC49B3D624F" modified="2016-11-30" version="1">MGETRIGKQKNILELAQKLSQKTKFTTDECKSLLTIHQRIAALGKVDRLRFREVLHTTFDITDDVMLDRVYRVFDYSNDGIIDETEWVEGVSLLCRGTADQLIDFCYTTYDINGDKSLAREELHHCLKGSLFPYSGVLNNDELEEGIREIVEIAMRKLDVDKDGQITQSDFTAACHSDPLLLQSIGPCLPPAKSLAAFMATFTENYRSYTSEWNDEWKVNMQGVSKKHSKINRHKKERASVASSSLAVPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFW9</accession>
    <name>A0A1D2NFW9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02497</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000053">
        <property type="protein sequence ID" value="ODN04163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFW9"/>
    <dbReference type="STRING" id="48709.A0A1D2NFW9"/>
    <dbReference type="OrthoDB" id="6479909at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF11">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="3">
        <location>
            <begin position="301"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="581" mass="63812" checksum="8EC4E85D15D7B1C7" modified="2016-11-30" version="1">MQSSKGISNLVIALIVVVICEFYGEIDGVMVKIPVAINVSKVLFTAPSFPPSEKSENTRLTHSACPLESCDTENDIVEKGPDKVFENDLEQDDEADDSEVVYDDDIIHETTLPSVHDTSTKKDGESVESKVLPRLITVNVPAVPPRTELKNDSRPLHKIYSNYPTIRLADFARKIIFPEWIWTKMTPPPPIVKKSEKPDPAISDSPSARPAEFNYNETFVPVTTTRRPKGILERPTITFDNNMSRFLRLFTVVRFQNVPCIGPSGENGTCYHNKECADLGGAGTTPCAQGLGVCCLFYKSCGDTIHRNGTYFVDSRAAFARGVSTCNINIQKLSPSIKHIRLEFHTFVLQPPNAGNCESDRFLVSGQNTNNIIPILCGNNSGSHLYIETGTSQSQIQLSVMTTGEGIRSWSIQINQIEEALSTYSAPSHCLQHFEGTMGVVTSFNYDSALSPQYLNNLNYAICIRKEAGFCSITYTNLVPDGQYFPFQVVNADPQGNLLLPSGQAGVGIRNCPDDFIILNGIRLCGERLNDGSKSTLLMDDAPVTDATNGPFTVMVRTNEIDVGGGFAIYYRQNPCMSTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG09</accession>
    <name>A0A1D2NG09_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Segmentation protein paired</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_02469</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paired homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000051">
        <property type="protein sequence ID" value="ODN04210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG09"/>
    <dbReference type="STRING" id="48709.A0A1D2NG09"/>
    <dbReference type="OMA" id="QSKCECV"/>
    <dbReference type="OrthoDB" id="3225452at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007365">
        <property type="term" value="P:periodic partitioning"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00131">
        <property type="entry name" value="PAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000710">
        <property type="entry name" value="Paired box 7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000003">
        <property type="entry name" value="Paired box protein Pax-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000031">
        <property type="entry name" value="Paired box protein Pax-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043182">
        <property type="entry name" value="PAIRED_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001523">
        <property type="entry name" value="Paired_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043565">
        <property type="entry name" value="PAX_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45636:SF49">
        <property type="entry name" value="PAIRED BOX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45636">
        <property type="entry name" value="PAIRED BOX PROTEIN PAX-6-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00292">
        <property type="entry name" value="PAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00027">
        <property type="entry name" value="PAIREDBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00351">
        <property type="entry name" value="PAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00034">
        <property type="entry name" value="PAIRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51057">
        <property type="entry name" value="PAIRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="6 10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0371">Homeobox</keyword>
    <keyword evidence="9 10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0563">Paired box</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Paired" evidence="13">
        <location>
            <begin position="16"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="12">
        <location>
            <begin position="172"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="10">
        <location>
            <begin position="174"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN04210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="251" mass="28425" checksum="81BEAA067198F1D5" modified="2016-11-30" version="1">MEENLSFKYMSLCGTGQGRVNQLGGVFINGRPLPNHIRLKIVEMAAAGIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPRVATPDVEKKIEDYKRENPGVFSWEIRDRLIKEGICDRTTAPSVSAISRLLRGREGETEKKILDGDKTSDLSDCESEPGIPLKRKQRRSRTTFTAHQLDELEKAFERTQYPDIYTREELAQRTKLTEARIQVKNANHDVAPVSQNRKELKILINAFKIQNNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGI4</accession>
    <name>A0A1D2NGI4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02311</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGI4"/>
    <dbReference type="STRING" id="48709.A0A1D2NGI4"/>
    <dbReference type="OMA" id="EQYTPNY"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF227">
        <property type="entry name" value="GLUCOSE DEHYDROGENASE [FAD, QUINONE]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="77"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="5">
        <location>
            <begin position="431"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="165"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="599" mass="67037" checksum="0857719F7968BB2C" modified="2016-11-30" version="1">MSLASLLHNKMDTIVIKLAVGLGLQNYIGWFAPVFLGMVNVVPPLMALFFYTDKSQTYNEHVSHKEHSGSKLPDLKYDFIVVGGGSAGSVVANRLSKHFNVLLLERGGEPNPLTVVPGMESSMLGRPEVDYRYLTVPQNNSCLACNNRQSLWNSGFGLGGSSILNAMVYIRGHPFDYDLWSYFTNDERWKYKNLLPYFMRSEGYCDNCEHTTGVIPSANPKFHGLEGELPVRPPPISPMVPDFLEALEWASVSKGDVNAPYYKPIADVASYTQKLGRRVTSYNAFVDTILDKRTSLKVLKYSRVIRVIFEPGTNTAIGVKYERFGKIEVAKANKEVILSADAVYQFLKNGTGPFTLTFARAVTLWTSTRALGSGEGEWPDIQVGMSSNGISQNFDEVLSQLYNLRADVMKEFLDPVKGQDAFSFILDYSRPRSRGVLRLASANYIDEPLIDPRYYGDAEQEDIRVTVEAIQRALYIGENAPAYKRLGSRLSPVPFPPCKNILFRSTEYWECVARQYSLTLHHFCGTASMGPVDSPHAVVDSELRVIGTKRLRVIDASVMPFIVSVNTNAATLMIGERGSEFVIKSWFIEYLPENEPHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGR5</accession>
    <name>A0A1D2NGR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chaperone protein DnaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000043">
        <property type="protein sequence ID" value="ODN04437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGR5"/>
    <dbReference type="STRING" id="48709.A0A1D2NGR5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000028">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="534" mass="60329" checksum="AFFAD0A1B8F7638A" modified="2016-11-30" version="1">MGANSASSDLKSLPSLTTWERKEKAKGSCMPRDDKKHFPEQKSRLNPLIFHLSLNHVRVGIEHESRFLQLPPVPAVVGITSENQWVCGEDDRLKEESTKVWLIRECNRPWHEQVRIGDNVNDITVEFLLGFLLGALKEHVEEMCNGEISQAIFIIPFWFTSSQRQQVKDSGTIAGFTENLLINENSALAFKAINGCNESSDIVVLSENSGHVDVTVYAYDKQKENLKMRGHYAVYEKKEKQRKQRPSMLSLEYLKFLTFGAEVSDSTGNAVHEAYKLAKNRLTLGKGSGSKSRPKIISSVLNLKIGRTYLCGQRKELLKKHIFLRNPISYEKTVQDNYNALPLNDAKLIISSDLPMYVSKARFYQKGVNGEAVIGDLNVKDSMDDICVKLEINNEGIVSLHCVNAKNRYSVRTRGGSERITLDSSLYSWTCPNLNPDQIGSYASLLEYFKEAKKASKVSSETEQAKQGLNEKGEELIQRIENKEGKFRSDLGRNMVKGQITEALGLLSHPKITPSDIEKQMDLFQKLEAKYFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHD8</accession>
    <name>A0A1D2NHD8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP synthase subunit epsilon, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHD8"/>
    <dbReference type="STRING" id="48709.A0A1D2NHD8"/>
    <dbReference type="OMA" id="IKFTQWK"/>
    <dbReference type="OrthoDB" id="269124at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1620.20:FF:000005">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="57" mass="6491" checksum="C7229E8AC2E62E73" modified="2016-11-30" version="1">MTFWRVAGLNYIQYSTIAARVVRKALKPEFRVEAAKRSESGIKFTQWKDGKPVTATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIG2</accession>
    <name>A0A1D2NIG2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01789</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000034">
        <property type="protein sequence ID" value="ODN04875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIG2"/>
    <dbReference type="STRING" id="48709.A0A1D2NIG2"/>
    <dbReference type="OMA" id="RCQVGPN"/>
    <dbReference type="OrthoDB" id="2355at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04646">
        <property type="entry name" value="LbH_Dynactin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027777">
        <property type="entry name" value="DCTN6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072">
        <property type="entry name" value="DYNACTIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072:SF0">
        <property type="entry name" value="DYNACTIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="18658" checksum="0918908A5C0A0EB8" modified="2016-11-30" version="1">MANLQITVGAVVCVEAEIRGDVRIGTKTIVHPCAKILATGGPIVIGDANIVEELATIENKSPEPMIIGNNNVFEVGSLVKAKAIGDHNIFETKCFVGDQISIGNGCVFGAGTKVTPSQAVPDNSVFYGEPLKHRLAGERPSAQTLQIDFLSRILPNYHNIINPTIKREIAVEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIS3</accession>
    <name>A0A1D2NIS3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Polyhomeotic-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01861</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIS3"/>
    <dbReference type="STRING" id="48709.A0A1D2NIS3"/>
    <dbReference type="OMA" id="YPNSIYP"/>
    <dbReference type="OrthoDB" id="2390104at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035102">
        <property type="term" value="C:PRC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09577">
        <property type="entry name" value="SAM_Ph1_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050548">
        <property type="entry name" value="PcG_chromatin_remod_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012313">
        <property type="entry name" value="Znf_FCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038603">
        <property type="entry name" value="Znf_FCS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247:SF138">
        <property type="entry name" value="POLYHOMEOTIC DISTAL, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21319">
        <property type="entry name" value="zf-FCS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51024">
        <property type="entry name" value="ZF_FCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FCS-type" evidence="10">
        <location>
            <begin position="670"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="9">
        <location>
            <begin position="784"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="348"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="512"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="709"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="406"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="512"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="526"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="709"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="735"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="755"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="861" mass="93023" checksum="8905F842A7352C71" modified="2016-11-30" version="1">MASQTHSGGTATSVAQQQQGVTQQQLQIQQPTTTATLQGTHQTGGQNQMQPLQVIHQSLQNQTLMPQQFYNTQGQLLMPGNIAFHPGLNPQIQQAQLAPSIQVIAAGKTLQPNQLSTPYSFNTSYTIPTSAANNQAYIIGQLNSQQQLSSILQQQQQTKPGEMQKLEMYCFHRTCNTAADWNDSANTCPDYVAIPQFLNQNSILIRGTQPDQMFIQQQQPLQNNTNTHQHFTMPLTTTQLPATSISSATTMEFNRPRQLCSLNPHYRFNHSLRKTKVEISNISHNRTAAAATATTTTTASKSTAPAATTTVATAVTANGSSATTNSNDSSRYGYISIKHVAATDFTKSTNADNSSDAPSPASAKTINHTSQGATQQLQPQSVTLIQQQPATQQPQPIRPNYSTAPATSTTISQQQGITTTATPQQRAKMRKPGVGRGSSNNASPTQQAKVMFPRPTIPTSISPLSAPLKPAPSSQQSVGATLTKVPISSQGPPQSVNNQPLKTINLAALHTPPTLPDATLTPLMPQSSSQGQTMQQAPQPLQVFPAPTTQLPSPNISITPAPPPLKKEEHHNENSSSQAPPPSSQQQQQNNSTQGNQHSELKSENEKENTKTETNTEESEESTGKQKLPKAMVKPQVLTHVIEGFVIQEASEPFPLGRNGDSDEPPMKKIALSGEMGKCEMCGKVDLRSKFKKNKRFCSSQCAKGMKAQQQQQQNSQQPSSVQNTTNNHYNNVNDSRKSKGKKWGESGESELTDETSSSVGEPSLMSPSTEQVDEEPKVNPVKWNVSEVVDFVRSLPGCAEYADDFALQEIDGQALMLLKEDHLMSAMGMKLGPALKLCAKIELIKAGMSSANGDGNQSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJH6</accession>
    <name>A0A1D2NJH6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Motile sperm domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01236</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJH6"/>
    <dbReference type="STRING" id="48709.A0A1D2NJH6"/>
    <dbReference type="OMA" id="VYNPYEF"/>
    <dbReference type="OrthoDB" id="10022288at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039283">
        <property type="entry name" value="MOSPD1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34441:SF1">
        <property type="entry name" value="MOTILE SPERM DOMAIN-CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34441">
        <property type="entry name" value="MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="7">
        <location>
            <begin position="17"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="124"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="27882" checksum="1A6EE77FF33558F6" modified="2016-11-30" version="1">MDRGRQKEDANLSRIPVFVFPSTMYFNAHDRDHLKQILTIYNPYEFPIRFRVLSNASTFYNVRVDEGTISSKNSLDLIIKVSTDVRLEATTPLKHKFRIQIFHQHTKQEVGRRDVESIIHFGNLPSHLGPTRDSDTSSIQGASSSEPFQQFPSGSMGSSKETAVAGSSGATSPMAIFPQTHSQPNYVVLIVALVCIVGLLLPYSTESCKANDSNKSHLESILPTYLHLSVNQKLLFAYTLGLVTMVILRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJM1</accession>
    <name>A0A1D2NJM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho GTPase-activating protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01377</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJM1"/>
    <dbReference type="STRING" id="48709.A0A1D2NJM1"/>
    <dbReference type="OrthoDB" id="6281275at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23175">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23175:SF23">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="286"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="717"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="911"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="990"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="717"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="941"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1104" mass="122166" checksum="4B1B58CA6C8FE845" modified="2016-11-30" version="1" fragment="single">GSSKPDKFTDSTEIIREGKVHFKIRIGENKRGTYNRSWRQGWAQARRSGYLYLSKERLQKEAVTGNEESVIISVSIRDGVFIEPAEDYTKRKNVLRIRTTFVPDDESNFPFVSTTEYYQNSVSVTSSSPQLTIEVLLQAEDPNDLILWLHCIQKQLENNNCNEETCSSSTQLNKGVAFGSEFYPKSKSFLTSLLPSPGTPPIQTSNSVDRTTNTTGVASSTSNSLNPNSVASMANTAASPKAKTWKGKVAKQWKKVHDIIDTTNTSTDNKSSPYASLPPAGATFGINLENCPPGEINPYVPRVIEYSIDLVEKKGIEMVGLYRIPGNNASVAILTDRLNRGEDPNPDKDSRWLDVHVVASLIKSFLRRLPDPLLTNDRYPAFIQAADENEETCLVKIKELIKGLPIHNYETLKAVVSHLKHVAEKGEMNRMDARNLAIVFGPTIVRTAGENFSSMVADMKNQCKIVEAFVLHVRTTHTKLSIFFRLCTVDFFYHSFLINNLVPQADKLFSETDDTIACPVVMRHPSRERKMCDETLSTSDTRKSVEVTKPLSPSSPVATIENELKVSLIKAAKRKVSAKENQPLFEHQQSLPADPKAELCKPVDEKGFIRSYAGLNEVTERRIRNFELETRAMLSRDDRSPNSSVFNIGAGSNKPVKAIDDIREQQLKLDDALRRAKDDLETEDIYDQIADNPSSIVHHRERGFGLCASSPGPFTLSNSSLSSSNSNSTAPSSLLTSSLPAWPTGNRNGPTPFRNSMPPQSLPPKPPTTASISSYPTSFDTVSPNAQVHSSMRRVNSFDRIQGSQSPCGVGNAATPNFNPMNISNKNSFRRSRRNDGTFAAGGGMITKQLGGSLDSLKDIVAETALMEDARLRTIRIGNDDDLSPRSSDGSDMVTTLTKTFDKKMEKLRNQFSETSLKTDPNDDISKEPTFPSESCPTAHNTDRTTSDGIPENKKLNYDIIQTSVPIQIDQIDIDQMNGSIHNNFIKKGRRRHSLIERRKTSFEGASKDFSAQSDGTRNNSASNTDSNSTPDSAIVKASKPKKLSKECRRRHSLSGATDILSLVFRGSEKLSVHRDSDAKKNKTLSSEALLTALKNASILESHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJM4</accession>
    <name>A0A1D2NJM4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase E4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01289</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJM4"/>
    <dbReference type="STRING" id="48709.A0A1D2NJM4"/>
    <dbReference type="OMA" id="RNMNEDW"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905655" evidence="2">
        <location>
            <begin position="24"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="28"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="97"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="484" mass="54677" checksum="79F885E40B9FD144" modified="2016-11-30" version="1">MDCRNGHLKYYITFVLLFQFVASIENPIIVSVEEGQLQGTKYSTRDGKSYFAFLGVPYATVNQRFEPPQPPVPWSGVRDATQYGSVCPQLVGQTNTLTGKYPIIVYFHGGGFMAGSGNLYGGSYFLDEDVILITLNYRLGALGFLSTGDSIIQGNAGLKDQNAALRWIKSNAHALGGDSNRISIMGESAGSASVSYHVLSPMSKGLYNYAVSMSGSALDPEHFERDPFAQAVDLGESLGCPTYTSEELADCLRQTDFRKIVQIKLTKWHLDPLVAYPPTIETLREGQSETDVFLMEEPLVLLQEGRFNRVPYVIGLTEEEGLLFHSAYILQKPELQRNMNEDWNYIAPITLYYDKRYIPDEERNQISRTIRGFYFGGRKVEPNSSRNLTNLYSDRLFNWGTRTAALLQAKFAPVYTYIFGYIGDFTMLQLYYKDLFQGPIAATHGDDLQYFFNSTRYPYLRWDTRSTQMSRALIRLWASFATTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKY0</accession>
    <name>A0A1D2NKY0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Radial spoke head protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKY0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009290">
        <property type="entry name" value="Radial_spoke_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06098">
        <property type="entry name" value="Radial_spoke_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="390"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="249"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="50147" checksum="42FE417728A6F9B7" modified="2016-11-30" version="1">MHVKIVTNSAISQVGETRIPAKATESRLSRRKTALHYHLQQVHKGFGLTNPHFHEHRFYRHGTKPKGYHDYQNLQWDPSIYRGRTFKDFREKNLPPFAPTINFNQYCSTDWKKQYQPKDLGIAPGKSKKIGLPRLKIGGIIRPTTDEVIDEEISGRNRHKQDESIKEMEPFIVEQVVIPKYKETGTNPDHVKPAPPKNCLHINVGLSKGSTADICLIGSEDDPIKPVVSCMGSKVLEQSLLESFEDYELRQIRREINKYMEKRRNRQIRETKVIHNELLRTLNLEKEKIRRENEFDEETAAEDIIGARIFSMLICNRLTCDVFVELRNQHFLQSGNAVNEKHFIPAIHNKLAQSLYVPHLLLNDMIRSIDYTRGPEWLVAQPSYNELYREDEMLGEEPFPEDHEEGESVVGPPPNSASTMLLTSEGEGESGMEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKY6</accession>
    <name>A0A1D2NKY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_00800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKY6"/>
    <dbReference type="STRING" id="48709.A0A1D2NKY6"/>
    <dbReference type="OMA" id="PNNISYR"/>
    <dbReference type="OrthoDB" id="8123669at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="46"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="28359" checksum="B8232F46F76DE0B9" modified="2016-11-30" version="1">MSLRFFEGQDHAKFYAKYRPIPPPELIERLVNFLQEKHDGPLSQAVDLGCGNGQCTFALTNAFSSVLGTDISPSQISEATACCKKMNVENVYEEARRVLVKNGVFAIIGYHLPVYMPQKEDETKYDSIKLAVDSAIEATREFWPEQALQVFHEYPNVNIPFSDFTRERGFTFQRKAKISDILGCICSYSPYQNFCKGKGENVGKDLLDNIANRIITTLNEGREKPLTEADFEEYEFTESVNYFVLMARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLA4</accession>
    <name>A0A1D2NLA4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLA4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="234" mass="27367" checksum="80BC4F95A29AC66C" modified="2016-11-30" version="1">MKLKRRSSYLIGFNGSDSLVIESFKDIIKLGRAQCLHLLQLFTCSESIGKMDFYRNFETYVARCTREARVWLRIFIVLLVISALPLTNGVINGKMKDKGLYVIQSVAEPRYVLTVAGDAIEKTRVEGELLSQVVTSKWINGEEQKWTVKSFGKHYYFLTPVEKKLNNVTYKIYMEDFPIPNIWELHGVEENKHWMIKMHRGKCLRLAGLESPLRQEKCDKKNEFQLWNFHLLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1A6</accession>
    <name>A0A1D2M1A6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007433">
        <property type="protein sequence ID" value="ODM86734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1A6"/>
    <dbReference type="STRING" id="48709.A0A1D2M1A6"/>
    <dbReference type="OrthoDB" id="6769745at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="172" mass="19257" checksum="10024229A9FD4D1F" modified="2016-11-30" version="1">MELDAALHFWIKFIQSRAFPDDKKQLLLTSEVSSSSKLIQLSPFIDHHGLIRVVGRLQNSKFRTPQKHPIILPPMITSRSSSSRIVICDTSTPVSSSLGLPSVELLDITLQRHHPPPDRKCITCPRHRAEAAKQLMGNLPEARVNPSLRSRAELVYLCLKTGGRVTHEQATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1W6</accession>
    <name>A0A1D2M1W6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006620">
        <property type="protein sequence ID" value="ODM86959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1W6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="11374" checksum="3EFF6DF1DB96969F" modified="2016-11-30" version="1">MVGGQAVNLTIGQPQVVPSIIELKGQGDHVGLTKGKIERYQWLLGWGGGRIFLNPTPPPPQTLGGRPEVIWRMFMVMGQREKGRNSSRSILDLANTEFKLALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2R6</accession>
    <name>A0A1D2M2R6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">39S ribosomal protein L2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005722">
        <property type="protein sequence ID" value="ODM87263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2R6"/>
    <dbReference type="STRING" id="48709.A0A1D2M2R6"/>
    <dbReference type="OMA" id="CCATILK"/>
    <dbReference type="OrthoDB" id="268576at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF73">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="5">
        <location>
            <begin position="84"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="4">
        <location>
            <begin position="174"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="327" mass="37239" checksum="6E79B5B58151F843" modified="2016-11-30" version="1">MCVSYRGQRQVQQSVPSREFHMSFNQLARFKEHMVEAPKPGKGNYFRRDVHYPEKYTIKPIPYTNMAGGIQRLIVFYNKNILFVRIVGHVVVGTLGGGIKHPFLWVDYKRHVPEGMEGPLIERVLQIVYEPSRTAHVALVGYADKLRYIIATENMKPGDIIKTSNEITKIAVRANEGDAYPLGSLPVNTIICCVEIHAGEGGYFARAAGTCCKILRKIGQRVVVLNAKKREISLPQNCMAVVGMSFSNVSWDTVHIGSPNNLRRMGYRPRSGLWHRKTGYHGRKLRRPPPCEEYVTKDQLPKPVPRIKLTMDPDVTHTYFKQFRGTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M360</accession>
    <name>A0A1D2M360_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005459">
        <property type="protein sequence ID" value="ODM87374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M360"/>
    <dbReference type="STRING" id="48709.A0A1D2M360"/>
    <dbReference type="OMA" id="WREETNI"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="24220" checksum="53FF8E1C17357B8C" modified="2016-11-30" version="1">MCAVVQDRVKGLLSHDYMKEDIYLVRFLRSRNFNTTLAEQRLKANLKWREETNIDNVRLEDFSDISSKYPVYMDTHAKNGAPVVTSASGVWNLVETHRTGKGQRLLRYLEKVMDSFLLRHGCPRCLIGIGYFLNSYENHFPGMIDKLVIVNATPTIQVVGPLARFATRSDFLSHVKLYGNNKEVWENYLQEFIDKDQLPVELGGTHTHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4R3</accession>
    <name>A0A1D2M4R3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004428">
        <property type="protein sequence ID" value="ODM87902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4R3"/>
    <dbReference type="STRING" id="48709.A0A1D2M4R3"/>
    <dbReference type="OMA" id="MMIDELP"/>
    <dbReference type="OrthoDB" id="7323790at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33198">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33198:SF20">
        <property type="entry name" value="RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29880" checksum="27502BD222D51601" modified="2016-11-30" version="1" fragment="single">MADDDEVEVKVKPETGPSKKADEGATKKVPESRLFVHVPLPGTLELHSGNVSANWKRWFLKWTMYELATGLDTKSGRVRIAAMLSSVGQDGLDLFQTFEWKDENEPKSYRAVMEKFEKWCTPRGNTMFRDVQIMQGESEKIDSYVAALKLQASNCGFGADDMARRIRDQVVLGLRDKKVQERVLREDDPNLDQVLTIVRAAEVAEQQSSKLTHGDSKSLEIDTGASCNVMSEKDYIRVTGDKSKVKLLPLDMQLSSYGVRLETTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4V0</accession>
    <name>A0A1D2M4V0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_18728</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004326">
        <property type="protein sequence ID" value="ODM87954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4V0"/>
    <dbReference type="STRING" id="48709.A0A1D2M4V0"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM87954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="74" mass="8085" checksum="2DEFAE8EFC1ECB85" modified="2016-11-30" version="1">MFSSHIKFRHNIYRDAWIVSLMDTCTSLLAGLTIFAVLGNLAFIQGTDVSEVVKGGGGAGLEFIFFLMLMPSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5B2</accession>
    <name>A0A1D2M5B2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vascular endothelial growth factor receptor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004027">
        <property type="protein sequence ID" value="ODM88153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5B2"/>
    <dbReference type="STRING" id="48709.A0A1D2M5B2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF617">
        <property type="entry name" value="RET ONCOGENE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="29688" checksum="B81C336B0C31E8B1" modified="2016-11-30" version="1">MDIVIRSAVVNLENVFKGIYTTKRENYEVIIKHQRDMHPLSLRALLQEIKIRVHAGTHHHIVALIGCSTANLRQGFMSQILSTHLKRFNVIIRRASDHLRILPKRDITELLKRKQIEVCELVHKGQFQHRVSMKKFQRPNISYVKSMPALSSYAFANLTLEIANGMGFLATKKVLFFCPTLGRLSTWRWIPLEVLETMEFSSHSDIWSFGVLLWEIFTLGEQPYPGVSSLTNEFIRDLGKEYALPSTRLRRQMLKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5T3</accession>
    <name>A0A1D2M5T3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin domain-containing protein UBFD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003740">
        <property type="protein sequence ID" value="ODM88337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5T3"/>
    <dbReference type="STRING" id="48709.A0A1D2M5T3"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039120">
        <property type="entry name" value="UBFD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057455">
        <property type="entry name" value="UBFD1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16470">
        <property type="entry name" value="UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16470:SF0">
        <property type="entry name" value="UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25343">
        <property type="entry name" value="PH_UBFD1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBFD1 PH-like C-terminal" evidence="2">
        <location>
            <begin position="153"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="266" mass="29449" checksum="1F64F4667816C784" modified="2016-11-30" version="1">MGDADRAAPAAAAADDPPTETEEPSKKLKLNGDAESANEAVTIEGKEEILNNNSPEVTLSIILDCSGAEETCSDAHWRRPQPPKGFDQGDCQGRRRAENPWRQCQYQKDSRHRLQHPGCAQRQGGAQRERATEAKKNEAAAAGNWCSLTQHKKVIDKGLPEDVMPGILEEHDPLPPFPLHGMYSSKGSKVRLTFKLENDELWIGTKERTEKVPISTIRNVVSQPITGYEHYHVVAIQLGPTEASRFFVYWVPAQYVEAIKDALTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M609</accession>
    <name>A0A1D2M609_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative chitinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_18268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003627">
        <property type="protein sequence ID" value="ODM88415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M609"/>
    <dbReference type="STRING" id="48709.A0A1D2M609"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903513" evidence="6">
        <location>
            <begin position="21"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="22"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM88415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="29289" checksum="E8C6AC79120094BE" modified="2016-11-30" version="1">MNFQIILLTCICAAFHLIKGENVECPSEGLYYLPHSKCIQFNICFDGEVAEMTCPFGLYYNPANTQCDFPENVLECRGGTRPPISSTTIVTEEPETTTELPPGTITECGQSIIADNGTVRYKLNEVYDAGELCVFMIKFESGALNTTFSLDDHGLIDSDYNAITVLLTDPYPIFAGNLGIFQQNVSFEGYGAVNEYQFGDRIPTELQTKIPSNFPMPILGTNLAFNDETTADTLFGLSVKGWYGHEDICSNGFWIFSFNLQTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M673</accession>
    <name>A0A1D2M673_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Eukaryotic translation initiation factor 4 gamma 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_18207</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the serine/threonine protein kinases MKNK1 and MKNK2. Binds EIF4A and EIF3. Interacts with MIF4GD. Interacts with DAZAP2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003549">
        <property type="protein sequence ID" value="ODM88475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M673"/>
    <dbReference type="STRING" id="48709.A0A1D2M673"/>
    <dbReference type="OMA" id="CAPLDIN"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11559">
        <property type="entry name" value="W2_eIF4G1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5 17" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="MI" evidence="16">
        <location>
            <begin position="609"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="W2" evidence="15">
        <location>
            <begin position="786"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="50"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM88475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="973" mass="111264" checksum="904381B3433D0606" modified="2016-11-30" version="1" fragment="single">VHRFSPQSPIFDEGATLSFIKITSAVAPFSPPLHFSKPFVQETTTEGPQVIGSASRNLGGRDEIRSQSSTSERWIPPSAIRRDALPHENSDDVKFRKVRGILNKLTPQTFDRLTEELIRIGLDSQVLLKGVILLIFEKALQEPKYVSMYAQLCKKLSKKVPNFDPPNPDNTTTFRRLLLNKCQDEYANRARASAMYDQKSAIGNLTPEEEEEKLLAKRKMLGNIKFIGELGKLEMLTHSILHKCCEELVKKTKAEDLECLCQIMSTCGHLLDNDKGKYLMDQYFDRMKELSENEKLPARIRFMLQDVIELRENHWLPRKTISLKESPKPIQEIRREAHDELGISDGSRSPTEEFRYLQIDPRRNGRIFGPKKRTGLEDVFAPVPIAMTSLGTGPGVITPGEKSLGMETNGFHTPPPMNNYRPAGGMRGYNPPNNMAPNNMAPNNPPYYQQHKNNMKYHQNHNNMHHNHNHDNHHGQMNNMHHNMRNNQNNMNNHVGYEKSPVAPRFMKQAQQANQGMVGAPPMPMSTMPMANEELSFRPPQNSMIKMIPQPMKPPTFVPPIMDPRKSPVTAVLPPPVINNPPPVENPLMQQGNKNTLERKKNTAPTKEDIIKKVDDIIGELIAKKSQEEALEAMKELKMPDRLYCDIIVAILNKAMDHNEPDREAVYSFVVYLVEQEFISVAQFQDSFRVMLDLMGDLEADIPRIKSYVAAFAGRAICQGQMTIVEVADLTENGKHYPFLLLVLQHMGKTMERTKLCKLFDESKVNLLTTLPKTDRTKDRMAEILEERELSFLFPLLKIQAEMAKRLQINSDPTDFLEWVKGQVDVTYQTSHGFIHALMTVIFKFINGEGLQGIKGNPSQAPEKQMKEKEKALLLKYKPVISTFLQDRVDLQVIAIYALQSAWFALECPKVMLLRWFMNTYELDLIEEDAFLKWKEDIRDDYPGKGKALFQVNQWLNWLEEEEEEGEEGEGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6U1</accession>
    <name>A0A1D2M6U1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative leucine aminopeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003351">
        <property type="protein sequence ID" value="ODM88641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6U1"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="10737" checksum="AA5E1875DF71A23E" modified="2016-11-30" version="1">MLKGETVWSPALTSFVKCWLRTISSGDQTGGGGLSSGQERCSSDYISWHRENHPWAAVTEVNENPHRNTEKDSIDQVNFEQVNEFAKLAWLLRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M740</accession>
    <name>A0A1D2M740_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003173">
        <property type="protein sequence ID" value="ODM88800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M740"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903569" evidence="2">
        <location>
            <begin position="25"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="23423" checksum="F4301D4BA6FCC94D" modified="2016-11-30" version="1">MLIIKPAFFLLILGFSMYSPRVSSLTADTIFHRLTCHRGFKLANPFVLTRLEDAVVNCISRYPNPKSVSTYRDCVNFCIAKEIKMLTMTKTGLAFNKLNLKFALNEWFGGGDDPWIVNIIADRFGNCVERHSNILLHQYQNCEANENNKSNQSELWLCLQNQLPCEPKPEDIKKEPNAPRTTMTKFDRGNNPKVSSDDDDAIMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8M1</accession>
    <name>A0A1D2M8M1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002715">
        <property type="protein sequence ID" value="ODM89333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8M1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="449" mass="51573" checksum="B9B2A3F3D91E4392" modified="2016-11-30" version="1">MSEPPTPKKFKLDESDDEVVEVEAVEVAEAAPPAENGEEVVEEMEVDGGEAVREVFASPNSTPFLPPENWIQILERRDFSSTDFYSIINTCPEFREMLKTERTAHLLPLVCANLSHEVRSEPDFPQISGVDQTNKIRDGQGTRGLPHKPIRRFHFSKTPRLYLDSQLKRINFKYMFSHRGQVHDFLDHFGNGDVTPECHPFPMGHVEFTLSDRGSEDFQIEYEDYLAFKFLLEGRRFGPHVSSVTFHISGYQDHDARQLFGKLSSLLHWIPNVKHLELRSHQKKFLLDGVVIGMLLGELVNRMDIFPSLPFLTYLNLDCLDIPENTLNRIIYHYGQQLEGLSINGALFTNPRLKDPDVPLKYLFSQVKVLHVYRPGVNALLILKSLKGWAVELIQFSGVREEAGDAPTTQHVEEFCESLFRELGNLKTVMCWDDNKLKAHVFKRPQRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8W1</accession>
    <name>A0A1D2M8W1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002651">
        <property type="protein sequence ID" value="ODM89427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8W1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903640" evidence="2">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="85" mass="9000" checksum="3871AA71519B8F58" modified="2016-11-30" version="1">MKVAILFLVVLAIVALSEAATPELEPQDFELVQDDKGNMETDMNEMASPNMAAPSQPESATPAIRVSSIDAYWNAIDATGAPAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAV6</accession>
    <name>A0A1D2MAV6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002239">
        <property type="protein sequence ID" value="ODM90004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAV6"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="7939" checksum="88DABB20DE85F6BF" modified="2016-11-30" version="1">MAERAPELLQIAEKYDLADLKEDCGYALAESLNKDNAPMIWSLANTLNEQGGSDGVSSYPFIIIHQDESSFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB72</accession>
    <name>A0A1D2MB72_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002135">
        <property type="protein sequence ID" value="ODM90162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB72"/>
    <dbReference type="STRING" id="48709.A0A1D2MB72"/>
    <dbReference type="OMA" id="MSVINSC"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903739" evidence="2">
        <location>
            <begin position="20"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="32797" checksum="553D7189C770C73D" modified="2016-11-30" version="1">MAKLFVVIAVTLAVVAIDAQRYGAHSGGGRGGSSGGYVEELTTVVRGTGGTGTAAGTNNAVKSGAICNSAGTWGKDANGQQCVCARPQRAKRHYNYYSGGRYGAHSGGGRGPSNYGYSGGYNGGNGNSNGGGLTWHCGSSAAGGSNGNTGGSTGNTGGSTGTGGGIIPIDNGSGGSTGSSGAGSGSSGGLGSAGPWKWLVEPGGLGKCWWNWEALVARVGLGSAGGTSGGLGSAGGTSGGLGSAGGTSGEVWGTWERRWLSNGGGLSNGGLSSAGSSGGSSSGSGLDSGTGMTTGTGTRMGGINSGLAGLTDTDGASEIDDNSETGDSSDETDEITPIESSTTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBH4</accession>
    <name>A0A1D2MBH4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein Star</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002092">
        <property type="protein sequence ID" value="ODM90244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBH4"/>
    <dbReference type="OMA" id="AFIINAC"/>
    <dbReference type="OrthoDB" id="408322at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="136"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="322" mass="36789" checksum="C9DE17A0EF9B5B8B" modified="2016-11-30" version="1">MLGKVYTIQKMKRVGLSRIYFAAVLCFFLILYIFQPSDLFLSLKSSLISYRATLGRSGPIIFDGELRKYILESGTSHQENPLLIELVRNELLIQPSTIPYNISSLDPKNVIPTNLEKLKMLEDLIIDKSKPGFFIECGANDGEFISPTLLLEQAYNWTGLLIEANPEPFSKLATKNRNAWLINVALCTRPFAKQVQFFTNPNNTGLAGLNERKYFGVNVPLNVQCVPLFTILAALNITEIDYFSLDVEGLELEILKTVPFDKIKFKFLTVEHWSIPGGRVALQLFMESKGYIFIKEVNDLYTRDSVFIHKSLRHKLRNLKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBP2</accession>
    <name>A0A1D2MBP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002022">
        <property type="protein sequence ID" value="ODM90349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBP2"/>
    <dbReference type="STRING" id="48709.A0A1D2MBP2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="19848" checksum="8AE7DB972DF8CE8B" modified="2016-11-30" version="1">MFLDENIISNSLTALAKADAQLVTFTQFQNAVTNNQGPIPTEEQYNNFINIAQSRGRISTVEEAAMALAQLLHESDRLQAMREYACAQIQCPIKPEDWAVRGCAQYDMNQKDIRECRDGRGIRGNEYHCCPGTGPAPTQSPGRGRPGGESGECSWYGAEGEIPPGHVVFAIQFLIVSRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC42</accession>
    <name>A0A1D2MC42_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">28S ribosomal protein S24, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_16173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001929">
        <property type="protein sequence ID" value="ODM90509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC42"/>
    <dbReference type="STRING" id="48709.A0A1D2MC42"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026146">
        <property type="entry name" value="Ribosomal_uS3m"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21244">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21244:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14955">
        <property type="entry name" value="MRP-S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM90509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="20849" checksum="B965044B7C21F12C" modified="2016-11-30" version="1">MIFGTSAARWPLALLKLNGVHPPSRSLQTCAILSKSQSGRHSPSIKHNKPLTYEQAQKPNEIAMRKSWNSMNTSALDFDPLGKFRLGARFGLRTSQTVNEDIFIRRFLVGTWHNLFLSEVLIKRQANMIRIAGIVLRAIPPRKMYFLIATLKNCSATAPVPCQARTTDCGGAEGCCVQVYLVVFCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD12</accession>
    <name>A0A1D2MD12_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kunitz-type serine protease inhibitor vestiginin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15784</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001755">
        <property type="protein sequence ID" value="ODM90897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD12"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF374">
        <property type="entry name" value="BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="43" mass="5160" checksum="586E7C829CE93215" modified="2016-11-30" version="1" fragment="single">MEHKPMFYYNAKENKCVKFHYKGCEGNDNRFNKLVDCQAKCVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD86</accession>
    <name>A0A1D2MD86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001715">
        <property type="protein sequence ID" value="ODM90976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD86"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="9324" checksum="B72C4FE98C6F131E" modified="2016-11-30" version="1">MDPASAGWAIVSAGSWVCSSLGTLGATATGIVIGVPVAATAASAAMAYKYGVTPALVVSGTSAVVSTGASVIVQGGKLTLRGFRYLISSEEDDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD92</accession>
    <name>A0A1D2MD92_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CLIP domain-containing serine protease</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_15729</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The clip domain consists of 35-55 residues which are 'knitted' together usually by 3 conserved disulfide bonds forming a clip-like compact structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01001731">
        <property type="protein sequence ID" value="ODM90950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD92"/>
    <dbReference type="STRING" id="48709.A0A1D2MD92"/>
    <dbReference type="OMA" id="WTHICSG"/>
    <dbReference type="OrthoDB" id="9028152at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000028">
        <property type="entry name" value="Serine protease easter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022700">
        <property type="entry name" value="CLIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051333">
        <property type="entry name" value="CLIP_Serine_Protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038565">
        <property type="entry name" value="CLIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260:SF145">
        <property type="entry name" value="FI17609P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12032">
        <property type="entry name" value="CLIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00680">
        <property type="entry name" value="CLIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="218"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM90950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="494" mass="55968" checksum="18B73F4AD2CD6B0E" modified="2016-11-30" version="1">MRMQRNSTHNSRSSSWSWCEQIHKRRWTIAVFSLAIILHSSTSEYTDACHSLQGKIGTCIPLNTCPLFLSWLKARPLVKENVRLLVKYTCYFDIRNPKVCCPNDSLYGSRDEFDVGFRIGAPSRLPESRNHDNKLLFPVSSLTFPSPLSNIVKPLKRNDDNLPLSFPTDHPSRGKSIIKNAETSLKPDFRQHPNFRLIPTLAECSNAVKLDSLLETYGAYPWIALIGLKPGRRSLDFDHFCAGIIINKRYIVSSAHCYQQANPRYVRLGEYDLDTLIDQGNEYLPQSRREDVRIEKLTPHPDFNPTTFANDIALIRLEKPLELNTTFIKAACLPFLTEYGIENRLNTNNISEFDGKPAWTAGWSRHSWDGLYSKGSDSSVIEEGIVEFTAHDKCRHDYPHMSALNSRTQLCVGGKGRRNSCVADSGGPLMVPVKVPSKISGFVEPKFFMLGLLSHGPTGRMCQNANDNEGRSLPTSVYTRISKYFSWILDNMQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME04</accession>
    <name>A0A1D2ME04_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="8">HIU hydrolase</shortName>
            <shortName evidence="8">HIUHase</shortName>
            <ecNumber evidence="8">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_15437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01001620">
        <property type="protein sequence ID" value="ODM91248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME04"/>
    <dbReference type="STRING" id="48709.A0A1D2ME04"/>
    <dbReference type="OMA" id="HDGRCDA"/>
    <dbReference type="OrthoDB" id="10265230at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00095">
        <property type="entry name" value="TR_THY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="116" mass="13110" checksum="6AFF1ECE940E48E1" modified="2016-11-30" version="1">MASNYNPLTSHVLDTAIGRPAVGVSITLSKYEGNGWREISKMLTNADGRVGNLISSEEFTPSRFKLAFDTLAYYESRGEKTFYPYIDVVFEIERPEEHYHVPILLSAFGYSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME30</accession>
    <name>A0A1D2ME30_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Glutamine synthetase</fullName>
            <ecNumber evidence="3 11">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15538</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="3 11"/>
    <dbReference type="EMBL" id="LJIJ01001652">
        <property type="protein sequence ID" value="ODM91144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME30"/>
    <dbReference type="STRING" id="48709.A0A1D2ME30"/>
    <dbReference type="OMA" id="IFLKPVC"/>
    <dbReference type="OrthoDB" id="1936100at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.70:FF:000004">
        <property type="entry name" value="Glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000011">
        <property type="entry name" value="Glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050292">
        <property type="entry name" value="Glutamine_Synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852:SF57">
        <property type="entry name" value="GLUTAMINE SYNTHETASE 2 CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51986">
        <property type="entry name" value="GS_BETA_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS beta-grasp" evidence="12">
        <location>
            <begin position="27"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="GS catalytic" evidence="13">
        <location>
            <begin position="114"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="41401" checksum="A89490B87F3FFEA3" modified="2016-11-30" version="1">MTDLPRISLSKKVYDRFMNLKIDENLSQLTYIWIDGTGEYLRSKTRTHYEIPKNVEDLPIWNYDGSSTYQAEGSNSDVYLYPRAIYKDPFLQGNNRLVLCETFKYNKDPTDTNLRASCVEVMNKAADQHPWFGIEQEYAILDRDLHPFGWPKSGFPGPQGPYYCGVGANKVFGRDVVESHYKACLYSGIKICGTNAEVMPAQWEYQVGPCEGIAMGDELWMSRYILHRVAEEFGVVISFDPKPIPGDWNGAGCHTNFSTQAMRDENGILAIEKAIERFSKNHLLHIKAYDPKEGKDNERRLTGHHETSSIHDFSAGVANRGCSIRIPRSVAEEKKGYLEDRRPSSNCDPYKVTEIIVRTVCLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME78</accession>
    <name>A0A1D2ME78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001621">
        <property type="protein sequence ID" value="ODM91243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME78"/>
    <dbReference type="STRING" id="48709.A0A1D2ME78"/>
    <dbReference type="OrthoDB" id="8032690at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19771" checksum="8A92E90BEC2E70C4" modified="2016-11-30" version="1" fragment="single">MPKQGRDFGTKVRGWLLQLQETERKYFVVEGQKVICTLEMNLRWTCAKLSSADIPMNKISNPHIRGFLEKYTKKDVPSQSTLRRNISDVYNEVIGKIRSEIGEPQFGSALTRQPIRHHDMLQCCNWSIEKTSLPSHIFLCLGSLLSPTIQQFHNLFWTHSCFYGLVNGTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEW4</accession>
    <name>A0A1D2MEW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001550">
        <property type="protein sequence ID" value="ODM91424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEW4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="183" mass="21503" checksum="47CB21BF477472A9" modified="2016-11-30" version="1">MDKNSTAGTLVDLHEQETDTELSDCETEEKGSSSNGGDNKAFVINADLEQERQKLAMEIRQLEVERLQLQREREEFKERAILMAKEVNEKIKNSNKQLLETEKRKEEAELRVRELEQRVREADQTFEEKKEQGNVAEDRLTRTQNATKEMQKNVQKLSKLRTIAESNLIVKERKHQRFQDTDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGH1</accession>
    <name>A0A1D2MGH1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alanine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_14700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 17">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001361">
        <property type="protein sequence ID" value="ODM91982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGH1"/>
    <dbReference type="STRING" id="48709.A0A1D2MGH1"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="14">
        <location>
            <begin position="3"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM91982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="932" mass="104927" checksum="46ED3A129AE8D69C" modified="2016-11-30" version="1">MKWSSAKVRDTFIQYFVKNTGFPHTFVPSSSIVPRNDPSLAFVNAGMNQFKDVILGFGRPQHVRATNSQKCLRINDLHLVGADTYHHTFFEMLGNWSFSNYFKKEACGMAWDLLTKDYGLDPDRLFVTYYAGCGTVPMDRETKLIWESIGVKPERILPFGKENFWQMGPIGPCGPSTEIHYDHRGTNLDPGSEINGDSGLVVEIWNLVFMQYNKMQSGELERLPLSHVVDTGAGLERLCAVLNGKVSNYDTDLFQPVFGKVQELSKVAGYGGDFSAAAERDRCYRIFADHIRAITVALGDGILPQTNQKIRRLIQRTLAVSDQQFQAKSLSSKDKLEFLMESVTQVGDSLGHIFPETTVLKPEISKILSVEIDRYSEFTSKQPGKTPTLSEIPEILLSDFPALSRISKEDLAQVKEKGNVDGSIAFKWYDSVGATQEAIEELCSAFGLTFDKTGMDQEMKRLKKQFRDEVTKEMIENEDRIFIRKLESLMALYNPQDSGGLCNPTMNVVREASPIFVEWMFDGSGDPVEEISTNDKESHWLILNKTPFVPGDIDFESDRGVLVLENGCKLNVEHVRQLPSGWILHLIKDVPEIGLSRKATIKKFEIDNGIRFGREMSIKAVAYTKWWLKKRYGVVRTANECALKETCQMTVTLLEGELTLPDIHQLQHDSNEQGVALVVTKKSNPSNKAGTSELICATGLAAEISLRYGQEVLDCLAEIQELCKEATTLNNDHNSKTKEVLKILVDRTSECVKRPDLLLPFEVYKEAEKVLHDAEKILWKNQEQMEITRMIHEIAGIAQEKKTSFVLKLFDSDHEFSSLKKVTRAADQKPILVLIRSTDDFIHGRCSVPKGLLESRGISAEDWMKCFTAKLGKGVVAAPKGQDGRFQVNLKRIRVYDCQDRLGPALESARKYIEDRVDKMFIEDGGSSRSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGN5</accession>
    <name>A0A1D2MGN5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alkyl transferase</fullName>
            <ecNumber evidence="4">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14630</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate</text>
            <dbReference type="Rhea" id="RHEA:53008"/>
            <dbReference type="Rhea" id="RHEA-COMP:19494"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:136960"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.87"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01001342">
        <property type="protein sequence ID" value="ODM92052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGN5"/>
    <dbReference type="STRING" id="48709.A0A1D2MGN5"/>
    <dbReference type="OMA" id="DFRAPHF"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="241" mass="27511" checksum="BD143255818D2BBF" modified="2016-11-30" version="1">MSSIPNHVAFILDGNRRYARKMNVDTIEGHKQGCKAFGNTVKWAATCGIKTVTAFVFSIENYNRSEKEVNGIMLLLKEYLEKTKQKSKELRDAGIRYQFLGDSSFFPKDLKLIMADVMKETLTNTRIVVNIAFAYTGRNEITSGVEKLVKQLANKEIDIDCVDEALLEQSLQVVPVPPVDLLVRTSECRLSDFLTWASSDRAVLCFVDVFWPDFSYWQFLLCVFHYQVSSARIRVSVKDCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIG7</accession>
    <name>A0A1D2MIG7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001155">
        <property type="protein sequence ID" value="ODM92763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIG7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="21673" checksum="EE79E41E0B0FC17E" modified="2016-11-30" version="1">MKILASFIGVTYAGVGVLGPREEAEALQLFANICSGYGSDGGRDIVYCKRGSGQLTETAHHQVRVPGGGSGAAQTVFIQPPPVRYIHRVQIQGGGGGGGVVEVKPRFTCCHKGLIMRYLQITDLDRVEMAVVQEVVVAAAEAAMGVPAPQPPSNYGAPAAQPPSNYGVPPAQLPSNYGAPVQLRTVTNFLSSGYKKREAVKKEIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIK6</accession>
    <name>A0A1D2MIK6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxygen-dependent choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001155">
        <property type="protein sequence ID" value="ODM92761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIK6"/>
    <dbReference type="STRING" id="48709.A0A1D2MIK6"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="16001" checksum="01269F84EDFE6DC7" modified="2016-11-30" version="1">MGIFDSLLKKIVGAGNAGCVLGSRLSENGKHTVLLLEAGQEPHPGLSVPAIVTNYTKTADYVRRYMSVPQRNANLESNGILAGHSPYDYDGWANITNDDSWKYSNMLEYLKKSENYQGNFPSDQHGYDGPIPVANHGMLQDWRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML51</accession>
    <name>A0A1D2ML51_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Failed axon connections</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000923">
        <property type="protein sequence ID" value="ODM93756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML51"/>
    <dbReference type="OMA" id="IALWRWV"/>
    <dbReference type="OrthoDB" id="5809458at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03193">
        <property type="entry name" value="GST_C_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like fold" evidence="4">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="3">
        <location>
            <begin position="270"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="40869" checksum="9804FD4444A9D9A3" modified="2016-11-30" version="1">MASGTITAAKALRPTASNANTVAENVASGAEYMADFVKSLDSQTVYTALGFAVATVGVGSVAYFLGGSRRPKPKRRTKVDFKDGKAATKSETDLESTCSNDFALDLKNGNVLILNQCPRGRKTPCIAPFPLKLETFLRVHKIEYELDFNGHEPKLFGSPWIRLNTEDIADTNAVIRTLIEAYDIKLEKGLTPEQRAITIAYGHLLNNHLYWGIALWRWVYDGARSVKDVQLLPMKTQLLIPDVCKTVEQAAWFHGIGKMSPDDVRKAVLADLGSLSEFLGTKKYFLNTPLPTELDCTAFGMLAQFLWNMNGPFHDAIADTYKNLREFCWRIRQTFWPDWEDCLNNTQFFTNEPYPVADSINYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLX8</accession>
    <name>A0A1D2MLX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000884">
        <property type="protein sequence ID" value="ODM93948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLX8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="104" mass="11676" checksum="A5E6965FA49B0C1D" modified="2016-11-30" version="1">MPRGKRKKVASPSYERSRSRTSSSDHHHHRKRRRHESPSSSPTTPTDSEVSSQTASKSRSRSKEKERAVSSSDESYPRKKNHKRCVGVDCDSGVLNVPTSSVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MML1</accession>
    <name>A0A1D2MML1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NCK-interacting protein with SH3 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000828">
        <property type="protein sequence ID" value="ODM94300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MML1"/>
    <dbReference type="STRING" id="48709.A0A1D2MML1"/>
    <dbReference type="OMA" id="ISMERMY"/>
    <dbReference type="OrthoDB" id="445362at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030125">
        <property type="entry name" value="SPIN90/Ldb17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018556">
        <property type="entry name" value="SPIN90/Ldb17_LRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357:SF1">
        <property type="entry name" value="NCK-INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357">
        <property type="entry name" value="SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09431">
        <property type="entry name" value="SPIN90_LRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="773" mass="87975" checksum="D850BAA8CF7407F9" modified="2016-11-30" version="1">MLRGLWEFRPINQKTLGFLMNDELLFIDAHARDKNWLRVASIHGHVGYVPINFVEIIQNVDLPRLLSFLDEAIRRAKQDRNRSLDCLLTFRDGLVASPIAPDEMILHMESEIKKLRAKSISELSNENSNLRSSYHQSDQQETSYASIVHAPKVVSNAGRIDTEETGSPKTGYHSRYHQHHPENSPHFPRHQHPYETETDMVPSPIVPEHRTTHSHSHTHTHSGSRTKSRGKKHKKPPAVIPTTISSIETQPAPPPPASYPSAVEVQSDFLESCAGQPGLLPSSVPSYPIIESGEPPVILSTLNCDNIEIVHPPPLSNNDLDSMQFLQKSSQGIDHQPSSFGIPDLTCQPRKWSIASGDRPVDPKLMAGEMIDVVRSATGLSHKKCQMAAQVVLGYIQECITELPVCLTSLMTHLENSKVISENPDVIAHSSDTYSIQRIFRFLKTCQADEQQRSWALHEDESVILDHLIELNQILEDADPSISKFALEQDKYNTVNTLVLYYQMETRWSIRSKLIDCFSSLCKIDLTALSVLLNSILPMELAREIRESLTDPTRLCQCASLLFFVLQTGEKLPIFHYEHLGLDFLSFVYNVIESPPDDDERITDVFVNVVFALNLQFSSVDDNLAIIALSDRHNAKVFTQKIIYYLNREYDPINIQELEYMELLKKPQHSVFKMTKDILSCKRTTDLFYTNDIKVLIDIVTRNLTDLGPGEARRTSYLQMIQRIIRNSNYSQHMHRIEDLRNCLVSILTEEDLQALPDQIVIRDMAKEFSFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMU3</accession>
    <name>A0A1D2MMU3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000833">
        <property type="protein sequence ID" value="ODM94278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMU3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="31524" checksum="EABE75A308F6E952" modified="2016-11-30" version="1">MSTSINSSLKPPKPPTKTRFSLKRRPSETLIRKSLYRTNSKKFLRPSINPVRKSIEVTTDEKTKDFVVHYQRYLHSHLTIDSEHEKYYLRYGLPKKPKYNPTGRRFSDSSESDPDYDRHQFQYEAAILNSKESPPESESNSSFVSGPTSHSSSATSKTSNHSPEHSFTDIMEVDNNHRRVSIQLKGTNEGSRYGPRKVREVEEPCFKSCIAFLKFLFCCKSPSHVNPSSPVHSAESRTMANRMIITPATDDTALQSKKRKSANQFLFVTPSIIVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMW7</accession>
    <name>A0A1D2MMW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor TFIIIB component B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12497</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000847">
        <property type="protein sequence ID" value="ODM94185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMW7"/>
    <dbReference type="STRING" id="48709.A0A1D2MMW7"/>
    <dbReference type="OrthoDB" id="272624at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001156">
        <property type="term" value="F:TFIIIC-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070898">
        <property type="term" value="P:RNA polymerase III preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039467">
        <property type="entry name" value="TFIIIB_B''_Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22929">
        <property type="entry name" value="RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22929:SF0">
        <property type="entry name" value="TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15963">
        <property type="entry name" value="Myb_DNA-bind_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="121"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="30846" checksum="11FDD4B6421002D9" modified="2016-11-30" version="1">MENSNKEIIVDDKKAASAPSSIASRRTTASSVGSGGSVVSVHDDCQSEAGSTASNNSSNVPGPRVKVGPDGQLIIDEQSLVIETSESQRARKQIEDMEVVSGADYAVGSSGFYRYKRSYRRGHDWTEKETIRFYRALNQCGTDFSMMLSLFPNRSRQELKSKFKREDRKNPDMVSKALASCHFDPDEGISSDEDLALYYGKTKNVEDVALLKRKSFYVRKWKWNKSFAHQKIPFKGKQKRRREKVEFTAAQKKEFNLTNFKGAGTGKGKNGTALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPE2</accession>
    <name>A0A1D2MPE2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000761">
        <property type="protein sequence ID" value="ODM94731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPE2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="486" mass="55243" checksum="AE5931554EEFF30A" modified="2016-11-30" version="1">MRATANKSIKRDISELTPVEKLLLQVTHPELYNSWFGSSTNKIPEGYSPFDFLNFDLPTLALQLSKSDGALILPSLNYTYGFYFCYIGVCSGVQQDYDYRNPEVVNANLTSLNTKINSTNIELDFKIPDLQIIIDNFTLSDTDLVSGATEYWKGFSLTITNYTLQLSADLEYVQDVGIQVSNVAMNFDVDDFRTLLGYEEGNVVETQYAEQMMEEWVEVGADFVNQRTIDCYINTNKTKDEMEIRTANSFWMISFKTENFVQLLQTFGLSILRSQEVLDRNVVAETKKEEAFLNFLPHLPTPTINSILLEYSTLMLQLGKFFYDPDHNLFPVVLYTLSYDNTWENCTDGVCRNINHKMILPCGLMATKEVYLGLQLSIWDNEFALSGKYELKEGVGLQVSDLGITLRLGKLQFRVPRFYTVENGEQSELQEYKVDAAPQIMEMWSSVDQDGAQNSTGCVKCNASEGQIQLLDLKLYTGKSNVPIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPG2</accession>
    <name>A0A1D2MPG2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_11800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SINA (Seven in absentia) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000736">
        <property type="protein sequence ID" value="ODM94886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPG2"/>
    <dbReference type="STRING" id="48709.A0A1D2MPG2"/>
    <dbReference type="OrthoDB" id="4788989at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004162">
        <property type="entry name" value="SINA-like_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049548">
        <property type="entry name" value="Sina-like_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013010">
        <property type="entry name" value="Znf_SIAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45877">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SIAH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45877:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21362">
        <property type="entry name" value="Sina_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51081">
        <property type="entry name" value="ZF_SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="73"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="SIAH-type" evidence="12">
        <location>
            <begin position="127"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM94886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="450" mass="50533" checksum="2E25F59B4A275997" modified="2016-11-30" version="1">MADPVDDTADDFQVGWNTPYPTAPPSFMPGAPELFTGGAAGPYPTIPGAPSELYPNIGFRPDLISATKTYMECPVCFEILTAPIYQCQNGHIICNNCINRIEFCGECRIPLGDSRIRNVALEYISQSMEVKCPNSTDGCEVLTTSGNLKIHLEVCDFRPIPLCSKHLGWTNCIEKVTASSAINHLREVHQVEEVEQAKFSLRLIAPPSAFQFAPGVTQEVYWNPLVITSALDDADAVLKCAVSREGYISFTCYLLGNNEDYKKYRIKLELDSSAKVARIEWTGSPLSYRQQPDEIPNINTFRLQLETLKEFCKPHSLDDGEEYSKLKVKVSVWKISDDDSPFRDCFRNADGEEEPLEKVFISSRSPNSANYSETMHHSDPEHYYSDLTCQHCSTSLFGIIYRCLQCPFAYYCKYCTERNVHGMHLLLRISSPEQQPLSEVVFECAAGELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPT6</accession>
    <name>A0A1D2MPT6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metalloendopeptidase</fullName>
            <ecNumber evidence="7">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000744">
        <property type="protein sequence ID" value="ODM94824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPT6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPT6"/>
    <dbReference type="OMA" id="KLANCYT"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="8">
        <location>
            <begin position="44"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="421" mass="46856" checksum="1AFB868FB933B86D" modified="2016-11-30" version="1">MVQKSVTMAKDQRYNLLYIFTISIITLSKLANCYTCDTSDDWLNVTQLETWPNGVVKYKLHASLTLRDTTEVQNAFEEFHTKTCIRFEPWQEGDLDFVSIEVNNSVCGAANVCKIGGYQVVQFGKDCRSKANIVHQLGHTLCLGDEHQRPDRDLHLNFSSCADDLIPGKIESYGFPMGIYDYASQMHSECGSCQGGWATDGYVEKCGQQISAGLSVLDVDKLNSLYNCQGCQRHRWVPAASLSSRDYPNVKTFGYESRNATPIYVCRAFLREQVTSGMYDESTKTCKLPWGYKAYDVQDQVEVLTIPGGTIGADCSSYQLKNWRDADISSFVNVGTRLTIIDSIHVAYSSFNTGSGEMEKFVGNVRFPTGNLRAEFPVGTEGLITPDYQAQFSGPIGNAAFEYGAVNFKLILATIRLKSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ97</accession>
    <name>A0A1D2MQ97_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Protein dachsous</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_11681</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000724">
        <property type="protein sequence ID" value="ODM94994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MQ97"/>
    <dbReference type="OMA" id="QPKDYTF"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005911">
        <property type="term" value="C:cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048589">
        <property type="term" value="P:developmental growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001736">
        <property type="term" value="P:establishment of planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="24"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000020">
        <property type="entry name" value="Dachsous cadherin-related 1b"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000116">
        <property type="entry name" value="Dachsous cadherin-related 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000226">
        <property type="entry name" value="Dachsous, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000015">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000033">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000039">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000058">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000165">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000092">
        <property type="entry name" value="Protocadherin 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000002">
        <property type="entry name" value="Protocadherin alpha 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000007">
        <property type="entry name" value="Protocadherin alpha 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000081">
        <property type="entry name" value="protocadherin Fat 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000275">
        <property type="entry name" value="Si:dkey-30k22.7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050971">
        <property type="entry name" value="Cadherin-domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24025">
        <property type="entry name" value="DESMOGLEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24025:SF23">
        <property type="entry name" value="NEURAL-CADHERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="24"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="24"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="23"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="31"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="134"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="265"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="379"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="486"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="592"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="696"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="800"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="900"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1005"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1116"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1225"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1329"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1438"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1544"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1651"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1754"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1860"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="1988"/>
            <end position="2078"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="2079"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="2181"/>
            <end position="2362"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="2362"/>
            <end position="2461"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="14">
        <location>
            <begin position="2462"/>
            <end position="2558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM94994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2561" mass="280497" checksum="F45A0387396B5C54" modified="2016-11-30" version="1">MVYIISFLGKTVGYTLLLLFLLTEPHLLASSEVIREFETSEGVPVGTSIGFIGEPTPGSSNSPPPPPYLIVPVPGSSVDTDLTIDQSNGEILTKVQLDRETRDSYSLVAIPITGENIRVIIRVKDENDNAPEFPMSSMSVEFPENTPRDVKRTLAPARDKDLGIYNTQRYTISAGNVNNAFRLSSHRERDGVLYLDLQVNGFLDRETIPSYTLLIEAFDGGNPPLKGSMIINITITDQNDNAPVWQFARLPNGDSQYMDDDITFNQSRYFATVAENASVGTSVLQVFALDQDEGPNGQITYSINRRQTDKESVFKIDPVTGVISVNRPLDYESKEVHELVAVARDNGIQPLETTVFVSIRIIDLNDNQLKIKISFFSDDSDDKPPTVSENAQPGEFVARISVHDPDSKQEYENVNMVLEGGEGNFALENRNGVVYLVVASRNLDRERKANYSFTIIAKDPENPNVNTSTSFSLQIGDENDSPPQFEKENYEASVSEVAGPGTSVLTVRAVDADVGNNSALVYSLKPSGNTYLKWFEIDPESGVISTKSHLDCETDPTPRLVVTATDKGEPALSSSAVVNIHLIDSNDTPLFDQSFYNASVMENTPIGRCILKVSASDPDCGINAVVVYSFQDTKGGQLPFSVNGETGEICVTGVLDFETKHVYEIPVVATDTGGLSSTAIVKIQLEDQNDNFPVFFPLKYNISLKERYVPDGPIISVAAVDKDSGKYGQVSYFIQSGNERGYFEVDGKSGEIRVVHGLARDTPVHQLLVSAKDGSGAVAEKPAVVTVTVVDAQQQPPLFKQARYSFAISEDAPVSSFVGAVAVSGGSKVRFSISSGDPEAYFTVDPSTGVIKTANKLDHELHRSVLLNVQAVGEQPPTTFSHCQVDIRIADVNDNRPEFEMQQVSIWVPENAKVGSVMYALHARDLDSGANGQVVYSWIQGPTDLFKLDASSGRITLQKQLDYEETKSYVIAVGARDMGTPPLASNNLTINLEIQDFNDNPPQWQPDTVQFRLRERVQAGSQVGRLSAHNKPAGGAIKYGLQTMANIFRIDPDLGTLTTAVSLDRGKLAQYKFTVAAFNQAMAQHKANITVNVHLVDSRNNDKKQAADTLKGFGDQPVNYEVTVPELLAIDSKIVQVVALDEDTGNNARISYSLASSSSSDDNESMFYMLPHSGALFLKGALDREVKDHYMVRVIATDHGSPALSSTAVISITVTDENDHAPLFEQKLFKFSLEENNKPGTVVGEVRAVDEDIGDNGAVFYSLQPPHGDFQIDARTGIIRAISSLDREKQSLYELQVLAMDHGSPQLQSDVIVHIVVSDANDNNPKITDPEQDTLIVREGIPVGTEIARVIATDPDAGENATISYSLAKDSFTDGKDFSIEGESGILRTRTTLIHEKKRFYTIGVVAKDKGKPGRESRREYRVEVLDVSDSRATSLLARNKYKFKVAENASVGFLVGSIMVRMEDNYSNSRLTYTIIKGNEDGRFEINRASGAILVVQPLDHEATSHYLLEVKVSIDSDTNPQDAVVTLDIEVLDVNDEAPRFPQDPMNVIVSENHSVGAPVWNFTALDRDGGLNGIIHFSIREQRPQEKFRINTLTGTLYLQSPLDYESCSSYILIVEAVDQSPLVSERLSTSVTVHMEVRDENDNEPQFTSASNIVVYKWEPANTVLHTVMAFDNDAGDNGIVSYEITGGNTNSELSLDNLTGQLSLVKPLKKTGVFSLNVTAKDHGKPSKSSTQLLTVTVKDVMDSPPQFSSRKYEVSVEEGTPVGSSIFQITAFPGEQSSQVEKLEYLIPEGAANGKFSIDKNTGTIYVAGELDREERSEYQLTVYVHDSSYLSFFDMTAIVIKVTDVNDNKPNFEDTCTDLEVPENSDLGVIHTFTAVDPDVGRNGDVSFTIAGGNVDNVFTVDLHSGRLTCRPLDRERRAFYHLVIVAQDQGVPPQKTQCNLTVTVDDENDSPIVFMSSNRSASGLSPYNISEAVFQESNSGQPSYYASIPEDIPVGTTVLFVAAQDDDIGINSAIRYALNNESHWHFSVDNATGAIVTAGGSPDGGTYDFRSATALVHLSVTDTNDNRPEFRTNPVVVDVPVYTKPGQSIAQVVATDSDEGINAQIAYSLENPDTRFRIQSQTGQISAVTSLSNDGGNVYHLTILAKDKGTPSQTSTCLVVIRVGDIGNVLNFRESNYIQSLPEDAPTGTSVVKVLATRTDGRRSSIVYNIVSGNEDQVFEINPSKGIIRVKKQELLDREVKSQFRLVVTAKADDSDGLNAHTVVHVNLTDVNDSKPRFTQSSLIYHIVDGNNDNAFLIDPPFSGIVKTNIVLDREITDEYRLTIIATDEGIPQMTGTCYLQVNVIDIQDQSPVFPPHSVINVSESVPVGTWITTVVANDVDTNPSLVYSFSKATQNPMFFIGKYSGRITLARPLDYEAEKVHAVEIQVSDSVHTASTILTVNVVDANDHSPVFAEDPYRITLSDEMKSGTKVAEVVAKDKDFGLNAKIKYSLEVPKDSNLRGPCFLRIDEDTGVIYTNSTMSKREENPFFVLILVATDQGEPPRSTRNTLWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQQ1</accession>
    <name>A0A1D2MQQ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Partitioning defective protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_11275</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell junction</location>
            <location evidence="2">Tight junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PAR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000677">
        <property type="protein sequence ID" value="ODM95407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQQ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MQQ1"/>
    <dbReference type="OMA" id="TEQSFDK"/>
    <dbReference type="OrthoDB" id="5868434at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005923">
        <property type="term" value="C:bicellular tight junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007098">
        <property type="term" value="P:centrosome cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06718">
        <property type="entry name" value="PDZ_Par6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000031">
        <property type="entry name" value="Partitioning defective 6 homolog alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000030">
        <property type="entry name" value="Partitioning defective 6 homolog beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051741">
        <property type="entry name" value="PAR6_homolog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14102:SF11">
        <property type="entry name" value="LD29223P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14102">
        <property type="entry name" value="PAR-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0965">Cell junction</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0796">Tight junction</keyword>
    <feature type="domain" description="PB1" evidence="14">
        <location>
            <begin position="15"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="13">
        <location>
            <begin position="155"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM95407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="316" mass="35182" checksum="7F8F4CB804083B79" modified="2016-11-30" version="1">MSKSTKIPNTRLSSHVEIKTKFEAEFRRFSMERAAKPTFDDFRTLIEKLHHMEDIPFLISYTDPKDGDLLPINNDDNLLLALQNARPLLRVLLQRKGDSQVDLNGSTNKSRTLISSLLTPRTKTTNHPLQISNPQDFRQVSAIIDVDIVPETCRRVKLLKHQNSDKPLGFYIRDGTSIRVTPHGLEKVPGIFISRLVPGGLAESTGLLGINDEVLEVNGIEVAGKSLDQVTDMMIANSSNLIITVRPASYQFLTPRRGSLTRTSQISAGSHLSASSQQSGSDDDRYDVDEIRDLTGIQLEDNQVSSNPTTNDELHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR06</accession>
    <name>A0A1D2MR06_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Voltage-dependent L-type calcium channel subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_11526</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Membrane</location>
            <topology evidence="1 18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000704">
        <property type="protein sequence ID" value="ODM95155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MR06"/>
    <dbReference type="OMA" id="QFMASAI"/>
    <dbReference type="OrthoDB" id="431720at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009582">
        <property type="term" value="P:detection of abiotic stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009581">
        <property type="term" value="P:detection of external stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042045">
        <property type="term" value="P:epithelial fluid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016322">
        <property type="term" value="P:neuron remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000007">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000009">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000107">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000001">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000006">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000010">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000064">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000063">
        <property type="entry name" value="Voltage-dependent N-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031649">
        <property type="entry name" value="GPHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014873">
        <property type="entry name" value="VDCC_a1su_IQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005446">
        <property type="entry name" value="VDCC_L_a1su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002077">
        <property type="entry name" value="VDCCAlpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF1">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE D SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08763">
        <property type="entry name" value="Ca_chan_IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16905">
        <property type="entry name" value="GPHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00167">
        <property type="entry name" value="CACHANNEL"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01630">
        <property type="entry name" value="LVDCCALPHA1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01062">
        <property type="entry name" value="Ca_chan_IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17 18" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 18" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4 18" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="16" id="KW-0407">Ion channel</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="10 18" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="534"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="571"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="663"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="726"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="915"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="961"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1040"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1166"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1246"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1276"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1308"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1371"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1456"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="domain" description="Voltage-dependent calcium channel alpha-1 subunit IQ" evidence="21">
        <location>
            <begin position="1614"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="836"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="2015"/>
            <end position="2044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="842"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1138"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR602077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM01062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODM95155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2044" mass="230931" checksum="39B00A9AFFC62789" modified="2016-11-30" version="1">MGGCTTWSLSRSEEEGAVGNYEIASGEGFPKIYPGGLSGSPSIVISPSSPIILSVAEVASPPPSGVAGPSTAANHKPLSSAWQCALSATSMTANKRRQAARRGKAVPDRPQRALFCFTLKNPIRKLCIDVVEWKVSQPCPLSSIPTGMSLALTDNMLFFLVSRPFEYLILLTIFANCVALAVYTPYPNSDSNSTNQTLEKIEYIFLIIFTAECIMKIIAYGFVLHPGSYLRNGWNFLDFTIVVIGIISTALSNLMKEGFDVKALRAFRVLRPLRLVSGVPSLQVVMNSILRAMVPLLHIALLVLFVIIIYAIVGLELFSGKMHSTCFDNSTGEMMKDPVPCGGAYMCEDENGDNINFTCRGYWEGPNKGITNFDNFGLSMLTVFQCITLEGWTTVMYNIQDSMGSSWQWVYFISMVIIGAFFVMNLILGVLSGEFSKEREKAKARGDFQKLREKQQIEEDLRGYLDWITQAEDIELDGEEKAKGANEVVAQDEGNGNDPAQLQTLPWFHSKKRDFDRLIRRMRRACRKAVKSQAFYWLIIVLVFLNTGILATEHYHQPSWLDDFQEVTNIFFVILFTLEMLLKMFSLGFQGYFVSLFNRFDSFVVVSSILEIVLTNSEVIPPLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFSLLGMQVFGGKFNFDSTEDKPRNNFDSFWQSLLTVFQILTGEDWNEVMYYGIAAYGGVSSVGVIACIYFIILFICGNYILLNVFLAIAVDNLADADSLTAIEKEEGEVAAEGEPTEEGRVVVVEACEENGSKELSEAGEQEQAGEEFHNNTDDVREVGEVHHQNSFETEGEDFEEGSKEEEDEAEEEEDEDVVEYDEEDAPAKAGARPRRMSEIKSSVKVKPLPKASSFFIFSHTNRFRVFCYWFVNHTMFGNVILVCILISSAMLACEDPLNDGSERNMILNKFDYFFTTIFTIEICLKMISFGFVLHEGAFCRSAFNLLDLLVVCVSLVSFGWSSNTFSVVKILRVLRVLRPLRAINRAKGLKHVVQCMIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKLFYCNDNSKISSDRCRGDYIYYDDNDITKPVVEEREWRNSDFNFDDVGKAMLTLFAVSTFEGWPQMLYKSIDSHAEDLGPIYNHRPFVAVYYIIYIIIIAFFMVNIFVGFVIVTFQNEGEQEYKNCELDKNQRNCIEFALKAKPVRRYIPKNRLQYKVWWLVTSQPFEYVIFILILINTVTLAMKFHGQPEGYTYALDILNMIFTAIFALEFVLKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEVNPSGKNISISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVMLFFIFAVIGMQVFGKIPLNSDTEINRNNNFQTFPQAVLVLFRSATGEAWQEIMIACQYKEDGNCTSAECGSDFTFPFFISFYFLCSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFAVVRTSLRIKTDGNIDEANAELRAVIKKIWKRTSPKLLDQVVPPPGVDDEVTVGKFYATFLIQDYFRRFKKRKAELNKGPGDKETQNAVTLQAGLRTLHDAGPELKRAVSGDLEELVNTDPEPMHRRNHSLFGTMWSSIRRKHGQLTRAKSVQENSKVEFFAHMHSVPSIFEVANHIGPSSKLSASIMNERKHRNEDGDDIPLRPLRVPSLPQVSYLETSTTIHGHSLSERETPPDRRVTRFRSRDLNAGAPSLTIAEGLHSANVQALALAGLTNVFNFGTVARPKLTFPNNVGQSASADELTPKRVYEKTMFNGGLGEDIGKSLRAPDSRAFSLPGVIGSAESLVLRVLTQQGLGKYCNDPEFVKYTSREMQEALEMTEEEMDRAAHRILMQERVEGVRILSFADLQKALEEDQAMAEDFEPNDEVIDMNEEEDVVDVDDEAVEVDDEDMGEIDDDIDLEEREYEDDIENVNDATPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR23</accession>
    <name>A0A1D2MR23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase 1, isoform C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000694">
        <property type="protein sequence ID" value="ODM95254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR23"/>
    <dbReference type="STRING" id="48709.A0A1D2MR23"/>
    <dbReference type="OMA" id="DHPIHPV"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03177">
        <property type="entry name" value="GST_C_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000007">
        <property type="entry name" value="Glutathione S-transferase 1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000295">
        <property type="entry name" value="Glutathione S-transferase unclassified 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969:SF7">
        <property type="entry name" value="GST-CONTAINING FLYWCH ZINC-FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01153">
        <property type="entry name" value="Main.4:_Theta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="88"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="28789" checksum="1E05011DA959395D" modified="2016-11-30" version="1">MGLKLYNLSDSPPCLTVRMALKYLGLEYDIVDVDFMKGEQFSEEYLKKNPQGEVPVLDDNGFLLSESVAIIQYLADKYKVDDTFYPTVAEQRAVINHRLAFHMSTYYKAIVNYVILPACYAYPKNEADLKKLEHAVGIFNTYMERQGGRYAAGSNITIADLPLILGTVCLEIISFDLSKYERVQNWYENFKTSHADLWEYGKICLDELSEFVKNPPDFSHLNHPLHPTDRSILDSNSPSAPADGPAADTPTPVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRY6</accession>
    <name>A0A1D2MRY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SET domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000612">
        <property type="protein sequence ID" value="ODM95869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRY6"/>
    <dbReference type="STRING" id="48709.A0A1D2MRY6"/>
    <dbReference type="OrthoDB" id="1928087at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10529">
        <property type="entry name" value="SET_SETD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="19"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="494" mass="54017" checksum="2E51979241F1A87A" modified="2016-11-30" version="1" fragment="single">MGNSSVPDPEFTPLSDDVKKWKLGVTSLEGGKKLKTLLAAVRVEPGEAIIEYIGKFLMLTGFQPTNKRSSQGNPNMISPEPFVFFHQVPKNGMCICIDCRKYGNDARFVRRSCTPNAEIRHVVGKGTIHAYVVATAVIDLDDEVTIPHEFKSVTCNTMNSVVQKYHVMSPPLPCACSDLDTCKAVATESVPGEVVHKKNGALISPTSLPHENKERRRRMSSRRTSSLDKETTESSRTPLASPSPQQLMIASPTESNKSLVSTTSPAEEAQDSSSVVVNSSKERPNGRTTRARTVAVSVEEPSTTPVSKRKTIVETPVTSRQRNRSGADTASYNNSTPSSGGGGDMYAAETHKMTREERKLQSVLKIIEKLESNQKKKESRQNQKKDKSGKSKKFEDRETDQDDDLQVTPTSVALAPIKFAPTSKKKGRKRGRSTSKSGGKPQLIMHRNSGSIADLRSTSTESDINSADEAAVRAAGMSPLQENMGPNFRLPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS20</accession>
    <name>A0A1D2MS20_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription termination factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_11072</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000646">
        <property type="protein sequence ID" value="ODM95604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS20"/>
    <dbReference type="STRING" id="48709.A0A1D2MS20"/>
    <dbReference type="OMA" id="NEVPQNP"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF50">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="224"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="597"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="774" mass="87394" checksum="2B6B115053924AF9" modified="2016-11-30" version="1">MEANEKNKFLCPEDIVDDAFEHMALNSAKPFSFTKKRDDTASTKKATGHGYFDEETEERDDSYPNSVKLDPALKSQLGDMDSGLQAVQETPLAPSKGFSMSQKLQLRENLQKMAKSGKWSADPRVSKDDLNNTPIPLGMQKSKQSPKIVLLEKAPPIEHPMVYGFDDSNNDEEYYGSVKMTVFMLTESLGTMPIPSENPENDDLPKGLVPLYDHQRNGLKWLSWREGVYPGGGILADEMGLGKTIMMIALIMKSKAEGPPEVDENWVDKKETIGLHPSDATLVVCPVGCVLQWQDEIESKGKGLRVQIFHGTHRTGSVTMLANNDVVLTTYNTVSTAVAKRKNAESQLESPLLRIYWRRIILDEVHNISNPKTQRAVSICRLSARHRWAVTGTPVYNTPADFFSIVKFLRIAPLDEPKVWDYCIGLKAFKTAKEAQDRLDAIRKALILRRTKTEVEAMGGNVRAIPPKTVETIELDLNEAETRVYDHLMKVSQAVFKNFMNKKDQRERETQGASMTYTSALHKTLGSDVSDDIKVTHLLARICRLRQCAVLPHLIETMLEEEQVDDDDSFDELKDEHLVSKRNPIFARDYESSKLKKILDDLEEIRDRAEAENKPMDKVVIVSSWTSLLNIISEHLRTRGFSFEFITGNEKMEERMSAVKRFNKYPDRPQIVLLSLATGVVGVNLTGGNYVFFVEPHWNPQMELQAQDCCHRFGQTKEVFIRRYVSKKTIEARVMELQAMKVDLADGVSKNANQSSNGISINQMALLFNSGVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS52</accession>
    <name>A0A1D2MS52_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Protein tailless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_10766</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the nuclear hormone receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000607">
        <property type="protein sequence ID" value="ODM95917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS52"/>
    <dbReference type="STRING" id="48709.A0A1D2MS52"/>
    <dbReference type="OMA" id="PRLYAAH"/>
    <dbReference type="OrthoDB" id="5771769at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07164">
        <property type="entry name" value="NR_DBD_PNR_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000058">
        <property type="entry name" value="Nuclear Hormone Receptor family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.565.10:FF:000011">
        <property type="entry name" value="Nuclear receptor subfamily 5, group A, member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.565.10">
        <property type="entry name" value="Retinoid X Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035500">
        <property type="entry name" value="NHR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000536">
        <property type="entry name" value="Nucl_hrmn_rcpt_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050274">
        <property type="entry name" value="Nuclear_hormone_rcpt_NR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001723">
        <property type="entry name" value="Nuclear_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001628">
        <property type="entry name" value="Znf_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24083">
        <property type="entry name" value="NUCLEAR HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00104">
        <property type="entry name" value="Hormone_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00105">
        <property type="entry name" value="zf-C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00398">
        <property type="entry name" value="STRDHORMONER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00047">
        <property type="entry name" value="STROIDFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00430">
        <property type="entry name" value="HOLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00399">
        <property type="entry name" value="ZnF_C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48508">
        <property type="entry name" value="Nuclear receptor ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51843">
        <property type="entry name" value="NR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00031">
        <property type="entry name" value="NUCLEAR_REC_DBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51030">
        <property type="entry name" value="NUCLEAR_REC_DBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nuclear receptor" evidence="12">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="NR LBD" evidence="13">
        <location>
            <begin position="216"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="175"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="433" mass="48296" checksum="98688A1A60C1D594" modified="2016-11-30" version="1">MDKEPKPDLLCRVCGDKASGKHYGVSSCDGCRGFFKRSIRRNLDYVCKENNTCIVDVTRRNQCQACRFRKCLEVNMKREAVQHERAPRTTTSKPKYLSHFAPAGSSGFTPYYFPLKPSFYPPFFGGSSGLTSGLPIGMFPTRTLGNSTGPGVGNVCLGETSLNSLSFSTFMIPPKTTSSSNGSSSPTEKELPTTIQPARSSSTSTSPRSGLPMANEDEVSSSGGEQEHNNHYKFLESLHVSTLVNESIYESAAKLLFLSVKWARSVPSFLNLPFEDQSLLLEECWVELFMLSGAQWGLRIDEGALVSGSVVPRTRHSALLVDARLLRETLERVQSIRPDHTELACLKALVLFKPEIPTLREQMQVEMLQDQTHVMLQEYCIGRAPPNKIRFGKLLLLLPLIRRIKGSLIEELFFKQTVGDIPIERLLSDMFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSD1</accession>
    <name>A0A1D2MSD1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WNT1-inducible-signaling pathway protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10976</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000631">
        <property type="protein sequence ID" value="ODM95704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSD1"/>
    <dbReference type="STRING" id="48709.A0A1D2MSD1"/>
    <dbReference type="OrthoDB" id="10068079at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052424">
        <property type="entry name" value="Kielin_Chordin-BMP_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46698">
        <property type="entry name" value="CROSSVEINLESS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46698:SF3">
        <property type="entry name" value="TENECTIN ISOFORM 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57603">
        <property type="entry name" value="FnI-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50184">
        <property type="entry name" value="VWFC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="VWFC" evidence="5">
        <location>
            <begin position="81"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="279" mass="29222" checksum="13299594D9F62A74" modified="2016-11-30" version="1" fragment="single">EAAITTERPSPIIQQTTEGGAPVDITELPVSLTPESGAAMMSSTEKIETADGISSTEETATSSSDDSDGSTDPSTNVPGEGSCYVEGKTYRNGSSIPPTTPCHIACACKNSIVHCLLVHCPPPPNNYVDCKPIYRSGVCCPEYDCGTTEGSGVTVTPEPPGGDKDSSVVTVTPEPASTEISESSSISSESAHTPDSSTPSSENLVSEQQDSSERPVTESTTDIVTPVQDQPGEGGAAGSSSETFRCFHEHPCIIIIFWRAIHNRSSSRATRVIHRLSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV37</accession>
    <name>A0A1D2MV37_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_09722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000484">
        <property type="protein sequence ID" value="ODM96960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV37"/>
    <dbReference type="STRING" id="48709.A0A1D2MV37"/>
    <dbReference type="OMA" id="CANCNAH"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00357">
        <property type="entry name" value="peptide-methionine (R)-S-oxide reductase MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173:SF52">
        <property type="entry name" value="METHIONINE-R-SULFOXIDE REDUCTASE B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="6">
        <location>
            <begin position="19"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="196"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="270"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="434" mass="46667" checksum="6437B6DEE8E9FB29" modified="2016-11-30" version="1" fragment="single">ARQQSNGTSSAAVENGSDINARKAALTPLEFRVTQQRETERPFSNKYNKHWEAGTYHCVVCDAELFQSETKFESKSGWPAFYNVVDAKRVKLTPDLSHIGANLLLLIARPELARTEVSCANCNAHLGHLFEDGPKPTGLRYCINSASLNFKSEGNEDITDPNGLSLPAPATTTCNGTGSAPIREYVCKPENMCSRPAATPKSVSSTNKDSPSGGKSARENFFTSGESNSSALPPMGTLCLNNQSCQRVLTRKPSSDNILKTSIISNGAENQVSSSTKNGVGVSNKETNINSNGNNGTENTTVMTPVSSKPRYSSSKGVSLTAARINFFQKISNKPDSSSPSRWASTFNSRWSSNKSSSSPLSNKVETVNNANRFPSSCSSGSLSTVSQHSKPDDLPPLQPRRSSSSFFSNSSLSPHIEQVSTPPRPVALRETTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVG3</accession>
    <name>A0A1D2MVG3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine triad nucleotide-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000474">
        <property type="protein sequence ID" value="ODM97080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVG3"/>
    <dbReference type="STRING" id="48709.A0A1D2MVG3"/>
    <dbReference type="OMA" id="YRVVMNC"/>
    <dbReference type="OrthoDB" id="672793at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01276">
        <property type="entry name" value="PKCI_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000005">
        <property type="entry name" value="Histidine triad nucleotide-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="HISTIDINE TRIAD HIT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="69"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2 3">
        <location>
            <begin position="161"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM97080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="19333" checksum="B541A955C7C2293E" modified="2016-11-30" version="1">MMSLIGYRSLLFACGKPLLSKPTFYSANSVKLTTVVGNRWLSTTNCRAMASEVEKAQAAKGGEYTEETIFSKIVDKKIPAKIIFEDDLSLAFHDVSPQAPTHFLVIPKKRISMLSKATDDDSNLLGHLLTVARKTADQLGLADGYRVVINNGANGAQSVYHLHIHVFGGRQMGWPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWJ4</accession>
    <name>A0A1D2MWJ4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL21</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L21</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000455">
        <property type="protein sequence ID" value="ODM97318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWJ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MWJ4"/>
    <dbReference type="OMA" id="INYGDYV"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="18514" checksum="DB4089680C8764BC" modified="2016-11-30" version="1">MTNPKGYRRGTRDLFSRPFKKHGTIPLGTYMKVYKVGDIVDIKGHGAVQVGMPYRYYHGKTGRVYNVTKRALGVIVNKRIRGKILPKRINVRIEHVTHSKCRTDFLERVQQNETLKREAKQQGLRVHCKRQPLQPRPAHFVSAKNNEPVLLQPVPYEFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWS2</accession>
    <name>A0A1D2MWS2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000436">
        <property type="protein sequence ID" value="ODM97510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWS2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="18234" checksum="906BD0FDBA15B6CB" modified="2016-11-30" version="1">MYLILTYVIPQAINLVLKLVWVISLLFVSFLVADIAIIIMIKAWYPDKVSVIGALEWALYTSLGFSSSFLNVFRYLVHSVFELVYGKVYQNQGEGSSRDRRESGRDADEKREKKAHAVVHNGVDQVSKNSAHRDKACHVLAHHQFVIFSEINQPAYTYCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX56</accession>
    <name>A0A1D2MX56_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000432">
        <property type="protein sequence ID" value="ODM97552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX56"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="27096" checksum="82FF72F05233AEA3" modified="2016-11-30" version="1">MEARNPIRVILLILQRRTNEGQGNPPITRMLGRRLRQEFAPPGSFSNSTRKFFNCLSFRFKSDFLLVVFGLLIVTMAPFILNHLISNDPPMLTSASLPLPNNSAALQTNFSIYHLHDDNIIRKVGGIGQDYTHAEQIILETEYRLQSCLKRNEEYVQTVLQFEEEISRLRENYSDLLLKERNTRQRLVLAVKRFRDEHLCIPMRTVYVFVILSIVLVAIVSIFRVGFKLNGLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXF9</accession>
    <name>A0A1D2MXF9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phenoloxidase-activating factor 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Prophenoloxidase-activating factor II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09309</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000449">
        <property type="protein sequence ID" value="ODM97375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXF9"/>
    <dbReference type="STRING" id="48709.A0A1D2MXF9"/>
    <dbReference type="OMA" id="TEIRIHE"/>
    <dbReference type="OrthoDB" id="6261922at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000038">
        <property type="entry name" value="Serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF129">
        <property type="entry name" value="LP15124P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904689" description="Phenoloxidase-activating factor 2" evidence="6">
        <location>
            <begin position="28"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="160"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00068096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00076468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="422" mass="46648" checksum="A7797413135F42B0" modified="2016-11-30" version="1">MSIWNIMDKHKCFIVLLSFLSVTLVSPFPNEDLDDPDLETEFINPSSTSVRLDKQDDICNCTSFFQCDLDASPTGGGINKEGMSPETSDEDENGADVGVIDIRNGFTSTTSTSSCKHYLEICCNHYQRTSKPRKPAEPKVPVQPSESCGRRNVHGVGFRIVGDDDGEAQMGEFTWMIAVTELTKDRHGTIYLCGGSLIHPRVVVTAAHCLENKSPESLRIRAGEWDTQTEREDPFIHHDRHVSKLIMHEDYSKRTVLKNDIALLVLSKDVPIARHIGPVCLSADLKPTQGQRCFASGWGKNLYGKEGSYQSILKKIDLPAIPNRACQSLLRETRLGPRFRLHESFVCAGGEKGKDTCKGDGGSPLVCEIPGSDSYALYGIVSWGLNCGDPVPGVYVNVPHFVPWIEERMKELGLDSSSFKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXI2</accession>
    <name>A0A1D2MXI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000414">
        <property type="protein sequence ID" value="ODM97747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXI2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="585" mass="65714" checksum="39D78878CA0C49F5" modified="2016-11-30" version="1">MKAGKLPTDIRLSFLQMLEKQQSNEKQARSSKDSRSKNQNDEGALSDDEQTKMLEAMKKSILESANLQQERLSNSSNKPSGPGGDDPIDEAHFEASLPTIPESNGESERNSEVVSPVENEDEGATRRGSVKSNKSNNDDDQQQVFKLTIENSNRNPFKNDSIGRLPFSGRKTESLVGKLSSDRINSLIAQNPFRKCFLFGDKNGVRDDLFKSGRQLPPEDFPKRRGNKVAFAEEDVNNNNVNNEQQPPSVTFQIPASNRSSDVLPFSSNEGGGGNARRKLCPGFLTQINELKGGEIVILWILKTSDLSAPHHHPPRRMDRREVGCGSSTLFQVAKTRNVCAQIGHSNLSGRNNEGGTQTVESSKTKMVRDEEVEPAGIYEGYQETFKSRETTNYSSDSSGSENSFPLPYNRNSYARRRRKHGRNKEYRHYEERRESRVEGSQQSPRYLNPPNQEMGYSGAHASESPRSNPNAGTFTRTINISTGRPPPPGHLPANQQQRQQQQQPNPQQPVFQRFIVNHNHPSANVIVRNQPCRQQASRHHLQSHRGSHLNSPQTRDSSLFKLRQQLGHLSHSLRDIRIKLNSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXM1</accession>
    <name>A0A1D2MXM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thrombospondin-type laminin G domain and EAR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000410">
        <property type="protein sequence ID" value="ODM97789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MXM1"/>
    <dbReference type="OMA" id="FENFHVD"/>
    <dbReference type="OrthoDB" id="7936313at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15261">
        <property type="entry name" value="THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15261:SF4">
        <property type="entry name" value="THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904717" evidence="1">
        <location>
            <begin position="24"/>
            <end position="2059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2059" mass="229117" checksum="77908741B7BA1CB1" modified="2016-11-30" version="1">MGHYEKILGFSVLVLSCFQLSSCVDLKQLFTPGNEELIQIIKEELDLFRVDMTKSFMDAHTRRRRAVTGHFKDITIKEDGISLEQTVDSVGPFSTFVFEGVPYLIQSSGIFRLDGLSALGTNKVLSRNEALTQVGSWKLQSNELVLHGYEWKHLYFLLTTDGQFSTIYTMHTSSLQPVFRQRILNKDNAVAARFFDYRRNLYLAICNDNEQHSTTFSSISRWAGSYMDKIHQIQTTGASAVEAFTINSKKYIAIAQTRDSTGDTLMGTLVLKMDHMERLDKFQLLWSNKASSLQYMTTEKEHFLLIGQENEPSIVYWFGGMDFIFWQQFDGLQGKNLMMDCLQLSADEPRLLASDGDSLRFYTRTVSATQITATWTESSFVKVASPSSSVKITQTRFLQVGENTIYLAVTRKSPSSKMESLKIYPVNFADKKPIESRTKETGDKLSECLQGLSSSLQEAKPALERIRTESVKILTTDTDLTFEGTLASEKIVKLDPSKSKVASAQISPEMQRAGSSERFKTAPSQLLSGIDDQIMMLDQMKAELQNVFYKSKPNQVQGKLTFSNGLQFDNLQLGSTDVTTSNLNNIAWSDIQNNALKVSSSKPQEVTGTWTIESLTTEDATVLNTNSQLAPDGFIRTSCTKQDIQAIMGVHQFEKSLTVDNNIQLGLSTTVNNIPFSHIVMKDDMQRQISGYKHAPHIKGDFVVDNVNDVHLPTWFSSVAKINSPTVQKFTGPVKIAENAALQIDQLKVVKLNTKTWDDFVANTMIDGVNQEVNGPVSFENLRVDNLQSRSINGVQSKNFLTSLTKQRITSEFSVETLTVTGPLTSASINGIHLTDAVSRTAKNVEISGPVELENFQVKDVTLPDGITIAEKDVSTLVDRKKVHMYTTVDGSTIFIKDVTVNEIQDTASLNGQLISDFATKYWSKAGNNVVDAPQLLISNRKSTLREGLITHSLNGFRFPNEFISLDQSRILLKAPVSFDKPVTVLGNVTMDEGKTIQKIDMSRINSMMVDKDFTGVIRGLKIFDRQVVAQEGATFGTLNGMDPVNDVVMLTTEESQVIDGIVKFTQPVELEDLHVDNGDVQVNGLVNNLNLEQVKTSTAYKDQENFIDGKVVFMKNINADKFSTVKLNEITAREITDNLIFLKHTDEQTIQGEILLANGRAELFGDSSTQIINGIPVSEHLSKVVMMDSPNLLISGTKEFTDVVLKDQLQCTSINGVNLEELARNAFSKSKSQFINGKWSLENVKFNENLETHQIGGVSLEDVVFTNQPTVEILSPVNFTSTRTTLQGPLTVVGDLNGVKFHEDMKNFININGGRKFDDVSITGDLTWTNDLPEMERLSYLFGNAVTNTNAQKILGGVHLAGGFSSSEIVSPDQWLNDINLQAIMDDALMKDDTNWVISGNNKFTKSLQIGNLVKPVDTLSTNLVNGLNLEMINEDIVKTTDDQSGRVIKGAKTFKGGIHANDLEIKDKLSDFSMQDFVVKDDSREINHVNFKNLLVSGNIDVTKTSGLDLQNLLEDRVSLTKPQELHGSYVFQNVNVEDKAQCQLQQINSISLENTLKAGSQEISNIGGEKVFKNGITVNGQIETSSLNDHNIQNLVDSTFRFDRKEVIQQPVIFESSVTINEQVEMESINKIHIESFSQSISSRIGRLVDEAKGPDFLLTVLSSQSTKLRRLTQQQPSWLEHFRLKQDWSMLGPKSRIAQMKSTTTGEIMVTLLQESDGQNVGLPKGCDCNTVDTVIIKEMNSKLTMRVGGDKCLQVFHATSPSGKAYTVTSDTSSSNTTCIAEKEKGITQIFSEDVLLEKMSTGHVSDLGVFSDRGTDFLILAQYFNKDTRSHTTTTSVFQVDHDGKVINVQNIETHGARQVAVSEINESWMLAIANSKNNIDEESCNADSAIYTWSSSEKRFLLLRTIMTDGAFDVEFITAKTNNPFYKESFVAFAQEGNSASGEVIIYRYEQLGGNFVMSQTLRSNWPITALRSTCICSKCFFITVVPQEGITFYENRFVEGFQEYHRVAVFGATDINSFTLNKLQLFAIATNKGPVLAEAVLAGSCQEEMFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYH8</accession>
    <name>A0A1D2MYH8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000380">
        <property type="protein sequence ID" value="ODM98117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYH8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="57895" checksum="8AF177C160F9B059" modified="2016-11-30" version="1">MSDSPDVLINHSTRSGKFHIIVHRCRETCKSIWITAAIISLVVLVGVLNATMNSTSEEKSNELNFTELLTASNLVESEKRTRFEFTTGRLIYGPKYVTDTHWNEHATFPTPEDFQYLAVDPLTILEVEINSALLDASIFSGYIQNFYNLRSLKLKNITIVGQFSRVYLPKLEKFYLEQTISSNEKLTDYKERERLKSLLFFEKSATQSWSLTKDFATLGIDLEVFIDGSKVLVASKTKSEITLTMSYCNDFLNNIPWPYDNLVLGNCSVSKRNIPTNIKSLLMGNVEITDGNLEDVLKSMTRIQSFSGSIPDVSIQISNLPSSLTFLCLTGIRLEYDEDRKLSSSSSTKLSTTIKQVAFGGDNLASSVVSQFDKIFPELEIIGIFGMGNKSYQLLHNVLKTKAQQIIVEFFPRESHPEAPAAQAVEEYLEKIGVETKYKNFILRTVEDDPENRIGGEISESESYFYRFTMLGWSKIDTFQKFLRVIAQGKVKEDSVQIAKKNGTDGVGGEKVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYM6</accession>
    <name>A0A1D2MYM6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Solute carrier family 35 member G1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000386">
        <property type="protein sequence ID" value="ODM98051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYM6"/>
    <dbReference type="STRING" id="48709.A0A1D2MYM6"/>
    <dbReference type="OMA" id="MELPEHS"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="14216" checksum="F5B770F0CA11D4CD" modified="2016-11-30" version="1">MLALGVCETVEGLVVSLFISPFEYPSWNVEDWGLACIIGVLFFCGQLTMTLALQIEEAGVVSLVRTCDVLFSFVFQVMFLQQEANIFSYLGALIVTTGVALTALRKWLMELPEHSLMRQRLFFILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYQ7</accession>
    <name>A0A1D2MYQ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000410">
        <property type="protein sequence ID" value="ODM97785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYQ7"/>
    <dbReference type="OrthoDB" id="6431318at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904743" evidence="1">
        <location>
            <begin position="27"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="103"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="277" mass="32022" checksum="3531D726E43CD110" modified="2016-11-30" version="1" fragment="single">MLFPSKTFSTIVGLILLVSCFSFISTQEETLSATEKAALEEFKLKILPKIPESSYVHKFAKDDLYLINWLRAGNWKVKSAMDLLMKHLEWRENESIDTIEKEDWANVIKEFPVFFDSVDKSGKPIIEVWFAEWQTRKAVLAGRLSTLSRMTTLAMESTSRKIWESRAEGKNVTQMIFLGELEGASVIQHMCPACLPVYLTMATNMENHYPYFVNKLYLMNMPASFDIILRLLKPILRASTRETITPYVNKDQWMKVLDETIDKNQRSVRFGGTIVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N056</accession>
    <name>A0A1D2N056_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein phosphatase PP2A regulatory subunit A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_08000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000336">
        <property type="protein sequence ID" value="ODM98673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N056"/>
    <dbReference type="STRING" id="48709.A0A1D2N056"/>
    <dbReference type="OMA" id="NTLCMTW"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000011">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="14"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase 2A Regulatory Subunit A helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="168"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="207"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="246"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="5">
        <location>
            <begin position="278"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="285"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="328"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="367"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="406"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="523"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="562"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00082658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM98673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="592" mass="65524" checksum="2F4DDBD223A811B5" modified="2016-11-30" version="1">MATTETCGDESLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVDRTRSELIPFLADTIYDEDEVLLALAEQLGNFTPLVGGPEFVHCLLAPLESLATVEETVVRDKAVESLRTISAQHSVADLEAHFVPLVKRLASGDWFTSRTSACGLFSVCYPRVSATIRSDLRSHFRSLCQDDTPMVRRAAASKLGELAKVVEPEYLKSDIIPMFVNLAQDEQDSVRLLAVEACVSIASLLPQDDTEQLLMPTLRQCAEDKSWRVRYMVADKFTDLQKAVGPEITKTDLVPAFQSLLKDCEAEVRAAAANKVKEFCQSLDPSVQEAVIMNSILPCVKELVADPNQHVKSALASVIMGLSPILGKNNTIEHLLPLFLSQLKDECPEVRLNIISNLDCVNEVIGIQQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVEFFDEKLNALCMTWLVDHVFAIREAATLNLKKLVQKFGAEWAENTVIPKVVAMSRDPNYLHRMTCLFCINVLADVCGQDITLKHLLPTVTQMASDGVANVRFNVAKTLQKIGPVLDRSTMTALLAPVLEKLKDDQDVDVRYFANEAITVLSLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0R0</accession>
    <name>A0A1D2N0R0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SH2 domain-containing adapter protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000316">
        <property type="protein sequence ID" value="ODM98852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0R0"/>
    <dbReference type="STRING" id="48709.A0A1D2N0R0"/>
    <dbReference type="OMA" id="HGAITRC"/>
    <dbReference type="OrthoDB" id="5914531at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001784">
        <property type="term" value="F:phosphotyrosine residue binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051846">
        <property type="entry name" value="SH2_domain_adapters"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15127">
        <property type="entry name" value="HEAVYWEIGHT, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15127:SF32">
        <property type="entry name" value="HEAVYWEIGHT, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0727">SH2 domain</keyword>
    <feature type="domain" description="SH2" evidence="4">
        <location>
            <begin position="735"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="101"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="393"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM98852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="834" mass="91657" checksum="A06FF18FA35E75FA" modified="2016-11-30" version="1" fragment="single">ISVNDDYIDPVDHVLNASLHHHHHHHDPPDVKTGAWSASSASGDTSSGSRKSGVTSEATSTSTHGSGETGSVIEPPYHEIRENYNAPYYYSDTIKEPTYVTPCENEGVESPSGTNSISDTSSPSPTFPEPVTVTVININAEEVGDERQFTSSSQRVPGLRKHTKLNRRSAYLRGANRKLMARKRYETAFLPSSTPHSSSQSTPDIDSLVLAIESSCQLGHDYVSKTDISQQKAAKNFRSCFQDSADTASGPQRENKFVERSGDQNKGQDAGVERRIIAISHPPNNTSSLETVESKLVQRDELHSSPLPPTCFPETTVISSSNFLPQTSVSYCRTSNLESTDVGSHASLQTNPSMSLCQQGQSHLFQHHYYPHHVHQNLNLNLHASRNSGLCTTTNSSPLATHKKPVMPLSEPLPQKRYITKSISSSGHNTTSSSSSSDPGETRRLGHNLKDTSVSSLESIDSMKSEDLPASLNRQPVNFYNSHHSSHYYPQKLLSPISDKSPLEPAGVLTSSHQTTFDDGNQQVKHDGSKWPNQIGLLNHSELTNVPWEMPKLRRKLAKLADSGISLDFAGSGSKETECGASSQPHYAGGMGARASMDLGLGASNTQHGITQGQSSYNKREMGATTLQLSFDDGLTRDEYYEDPHYTLHEGHTFESSYGSSRHGFLTASKIPGSAIMEDVTVQVHVSQQHEKPSAASIKPDRCRMKLDFSSTGFGLFQNPANVIDPTIELERQDWFHGAITRCEAENILRATKEGSFLVRNCESTTFNRYSLSLKSFRGCIHIRIEPNSLGTFSLGDQEFPSVPHLVLHFMSHRLPIKGAEHVRLMYPVITQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0X5</accession>
    <name>A0A1D2N0X5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Tyrosine-protein kinase receptor</fullName>
            <ecNumber evidence="17">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_07785</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 24">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="17"/>
    <dbReference type="EMBL" id="LJIJ01000313">
        <property type="protein sequence ID" value="ODM98888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0X5"/>
    <dbReference type="OMA" id="HPIVYLN"/>
    <dbReference type="OrthoDB" id="6071166at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005518">
        <property type="term" value="F:collagen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038062">
        <property type="term" value="F:protein tyrosine kinase collagen receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010976">
        <property type="term" value="P:positive regulation of neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051897">
        <property type="term" value="P:positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048525">
        <property type="entry name" value="DDR1-2_DS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002011">
        <property type="entry name" value="Tyr_kinase_rcpt_2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF579">
        <property type="entry name" value="DISCOIDIN DOMAIN-CONTAINING RECEPTOR 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21114">
        <property type="entry name" value="DDR1-2_DS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00231">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01286">
        <property type="entry name" value="FA58C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00239">
        <property type="entry name" value="RECEPTOR_TYR_KIN_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13 17 22" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 17 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="21">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="565"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="332"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="598"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODM98888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="878" mass="99165" checksum="8D87D00F2453F4F7" modified="2016-11-30" version="1">MKKKEIYCLGKAIKVNGVRMELQGGAWCPRNMITSETEEWLQIDLHNVHLITATETQGRFGNGQGQEYAEFYKISYWRPELNNWIRYRDHTGNEVMKGNINTYLAEKSELNPPIYASKLRIIPFSRHRRTVCMRSEVYGCIYKGGLVSYSMPQGSMRGENWNFYDHTYDGIWDGNHLQNGLGSLADGRVGPNNFKDDFYTHERGKGWVGWKNDTSKNGSESVEIIFKFTSPQEFFAMHIHTSNQFTKEVQVFSEARVFFSANGKVFSGDSIVVKQKEDCIFEEPRNITIKLHRRVAQYIKLQLFWAAKWILISEVTFDARPVGSQRVVHSGISTTSSEDGSLAQSDASGSGASNTLSRETPPMAGPPALSHSKWSPATIIITAVISSVLAIIIILTILLTVILVRRRVLGSRKVPKTPEGTLPFDNSNDFGYASPDEIRKYKISTSDYTEPFTTAPVAAAPPPLTTFPRSSFNPSTTGGDSGVGSKRMADYYICTLIPNATQPTVADSSNEYEYAVPNELGKLLPSQQPSPLKSIPNSPATANRTRMMLLKFKELGIPEIQKHRLRMLRKLGDGTFGSVFVGELDQSGIAEKQLVAVKHLLRNATDKDKSDFLEEVRLLWTLRDPNIVQVLGIYVEEDPLSVVLEFLELGDLCQFLRQNDTLLPNSTKKISFGSLLHIASQISSGMKFLESRNIVHRDLAARNCVVGRGLLVKVSHFAKDTDLYATDYYRLDGKMPLPIRWMAWESLFLGKYSTKTDVFSFGILFWEILTYCRHSPYPTFSNQEVLNNLRRLSVVEDLDPFEPLSKPQSCPRDIYQLMCDTWSRNDDNRPTFWEINSFLSRKNLHFTTHGTISHESYKNSSHVLPTSSSLSGAEHYMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N315</accession>
    <name>A0A1D2N315_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_07056</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2-methylpropanoyl-CoA = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:18865"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="2.3.1.168"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:18866"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000267">
        <property type="protein sequence ID" value="ODM99630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N315"/>
    <dbReference type="STRING" id="48709.A0A1D2N315"/>
    <dbReference type="OMA" id="MPFCIKA"/>
    <dbReference type="OrthoDB" id="202158at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043754">
        <property type="term" value="F:dihydrolipoamide branched chain acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031405">
        <property type="term" value="F:lipoic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000013">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000027">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.320.10:FF:000002">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 10" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="59"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="13">
        <location>
            <begin position="175"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="217"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM99630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="497" mass="54197" checksum="A94D213C1EC7BE1C" modified="2016-11-30" version="1">MSHGSSSTRVSRTAIVQQHRFKGSLSSPLVATSSFRHGNQLIFNWARFVHVTQSCHKEIIPFKLSDIGEGIKEVTLKEWFVKEGDKVNQFDQICEVQSDKASVTITSRYDGIINKIHYQVDDIALVGSALVDIEIVESEKPPEEQEIQEGDAIQVGRSEESFHLPSQPLPLEKALAAPAVRRIAAEYKIDLKNVQGTGKDGRVLKEDILNYISSKENVTTSEQPAAAASTTPGPPAPQPSSPATPAQTPSPAAIPFTPRSITAPSDRKEAIKGYTRTMIKTMTAANEIPHFGYCEEINVTELINLRRRLKDVADQYNIKLTMMPLFLKSASLALSQYPILNSTLDVASDSIIYKGAHNIGVAMDTKLGLIVPNVKNVESKSILEIATDLQNLHKSAQGGSIKPDDIRGGTFTISNIGSIGGTYAKPVILPPEVAIVAIGRVQTLPRFDKAGNVVPAQMINISFSADHRLIDGATAARFCNLWKSYLEDPASMLLHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3U1</accession>
    <name>A0A1D2N3U1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Equilibrative nucleoside transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000245">
        <property type="protein sequence ID" value="ODM99939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3U1"/>
    <dbReference type="STRING" id="48709.A0A1D2N3U1"/>
    <dbReference type="OMA" id="WVYWGIA"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF80">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016379">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01130">
        <property type="entry name" value="DERENTRNSPRT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM99939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="488" mass="55210" checksum="0C645823C260BE47" modified="2016-11-30" version="1">MAGEKRAPLASIDDFSSICYYSPGRPKKLSDFSMPLLRKGEQDGGIELMENSENVENIAKYNVNKKLRPLVKVPQDRFNLVYLILVIHGVGTLMPWNMFITAKDYFVSYKLSEKYTGQQSEYAANFLQYIGFAAQIPNVFFNWFNIFIQIGGSLKTRIVWSIVIEVILFIFTVVLAMLDTSEYPGVFFWLTIASVVVINMAGGIYQNSVYGIAAKLDYTGAVVLGSNISGTFTSIINLISLAMAPSERTAAIYYFITALFVLLTCFDTYFALPLTKFYRYHEMMSAREQENKRQAGRRGVSQRTPYFAILKKCFPQCFNVFMVFFVTLAIFPAVHSDVKMVNPDFVIPDKYFVGVTCFLTFNLFAMLGNMVPGLFQWPGPKYLWVPVMLRILFIPFFLLCNYQPKDITRVFMPNFAFDDWTYWSGGVLLGLTSGYYSSLAMMYCPRCVETEYAPIAGMFGAAFLITGIFAGINFSLLMPILVSKVAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4R7</accession>
    <name>A0A1D2N4R7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="9">PPIase</shortName>
            <ecNumber evidence="9">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_06428</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000221">
        <property type="protein sequence ID" value="ODN00253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4R7"/>
    <dbReference type="STRING" id="48709.A0A1D2N4R7"/>
    <dbReference type="OMA" id="APKCCEN"/>
    <dbReference type="OrthoDB" id="2083at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01921">
        <property type="entry name" value="cyclophilin_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000079">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000287">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035538">
        <property type="entry name" value="Cyclophilin_PPIL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="11">
        <location>
            <begin position="6"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="240"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="332"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="362"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="403"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="432"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="474" mass="53872" checksum="E5C494A3458F8FC9" modified="2016-11-30" version="1">MSVVIETTLGDITVDLYVKERPKTCTNFLKLCKIKYYNYNLFHTVQRGFIAQTGDPTGSGRGGESVYGLLYGQQAKYYEAEKIPIIKHVKPGLISMVNCGDQMLGSQFFITLGEKLKYLDAEHCVFGEVTEGHDVLEKLNEAICDGENRPYQDIRITHTIILDDPFENPRGLDIPSRSPSPTPEMLDSGRIRADEDIDDTKGKSMEELEEIIKEKEAKARATILEMVGDLPDADIAPPENVLFVCKLNPVTSDEDLEIIFSRFGKVKSCEVIKDQKSGESLQYAFVEFEDRKACEDAYFKMDNVLIDDRRIHVDFSQSVSKFKWKGKGRGVEVVDNNKNKSDSTTRRPRAAWIRDPSASKSHSSDDLKAEKDNSWKKSRDARIAHANDGSKKHWSRSPPRYSRGHESTQKRKSDDKEHKSTDEKLLKLLKKEMKKQKKKKSKSKKKRRDDSRSSSGSDSSSDDGESSPRRKRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N646</accession>
    <name>A0A1D2N646_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000188">
        <property type="protein sequence ID" value="ODN00743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N646"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="11680" checksum="F987418724F3DC5B" modified="2016-11-30" version="1">MQNLSDAGSGFQLDTPSKMGDFVWTKEYLEKMVLSTVYFDKDNSKNPTLILPHKGPMRPLKMFAAYKQFCKLAFVGGTPLPDCPIQCYEKQLLELLGPESDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Z4</accession>
    <name>A0A1D2N6Z4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger CCCH domain-containing protein 7B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000176">
        <property type="protein sequence ID" value="ODN01011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Z4"/>
    <dbReference type="STRING" id="48709.A0A1D2N6Z4"/>
    <dbReference type="OrthoDB" id="420195at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="115"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37402" checksum="9F1158B07AED7A0F" modified="2016-11-30" version="1">MNETNRFGTSSDGNAKVANGKCDGDSNKLNSKAEEESDDDVGSSSSRNPQFFLKEGNMQFIYKNFTSAISTYTHGLDLFNEELCGDHPVVVVENEPDKKIRSVSGNTNENRTVILELFTNRALAYLSIGNYTAALEDTQKALSINPTHFKAIFRKAKALAGLAQYQNAIGFVESSLKRLTKKNKQESVSDCKELSAYLEKLRRMKQQSEAGDYYDVPYIMERLYEPTPADWVDYIGPVKVEKFPGKGRGLVAAQDIPPCKLILACRAFEIIFLDTGSPDPEECLSQESKKALFNGDIKVEDDRTLNFLARKIYDRLVRNPEKRVDFYQLHAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7K4</accession>
    <name>A0A1D2N7K4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAST kinase domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7K4"/>
    <dbReference type="STRING" id="48709.A0A1D2N7K4"/>
    <dbReference type="OMA" id="XRYLANS"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010622">
        <property type="entry name" value="FAST_Leu-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06743">
        <property type="entry name" value="FAST_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="771"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="839" mass="94998" checksum="98B6DF1EFAAC14D9" modified="2016-11-30" version="1">MTGEFWNRLRTRQCQMNRNDDKLMTLTAITKCIKISVEWSYDKSKWHHCVVSGIAKCTTTKCSSGSVVVYRYCSRSAHCFMPAVSKSSGPHLSSYVSMPPVSISCGNALAKLKNLSFSTRRSNLNHGCQRHMSSWLRSSGVLFIKGTNDGGDDTGFPTNNTRRPRTGKELGETSILRQDGHNIDEVPAAVIRSDSSDKPTKGPLRTYVDLDPTEEAAFIEGFSNFHTPQQVLKLLDTIPSQEVTPFVSYSILKKLFELESNFGFRNDGRSWLNASDNSSTETFARLAIVTRLIDTITTTDNNSLLLDTVDLLRRESQSENISTHSVYESENQLEYKNKLLQEVLIRVTEGKLELEDVCKAVVILGKLEEDNGFSLNGDFIDKFWVGIMDRSDDINSENVVDVLRTVKYFKKSSRLVLNLVERKLMSLWWKLSTETVADICSILTSDDGPVKQAGAIAPEKTSHGMTSWQVTNRLLMTLSKCCNLNIHKVTEKELTKIVKAFYTLNFCDSAIEQALNKYMKAKCLKITDPQLVSNIMDFSRKFRLRFPNILEAASQFVVKNNASNLSPPQFASILRSFGDLDFQPTEGPKFWEIVENYLSEKFIQFPPKDVVSLLLSFVYLMKYPINFVDKTFSPYFLDRLHTSEPDFLRLQQHRSSLKLLDIAMTVECKNKYGGPLLPKDFTSRTIFIDGRILRMSNVLKEALMGICVNSSIDISVVLPSLPLNPIFTADIILTTPKLESETDRHNFLRSHITSYLLYTTPPPSAKHSDLTVILVNIPEHFSSDAKYLIGMQSMRKRILKSLGFNVVSMKYQELNAAKNDFNMLTEYIERKLGDLPCIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N876</accession>
    <name>A0A1D2N876_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000152">
        <property type="protein sequence ID" value="ODN01441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N876"/>
    <dbReference type="STRING" id="48709.A0A1D2N876"/>
    <dbReference type="OMA" id="MFCEKAT"/>
    <dbReference type="OrthoDB" id="10252587at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="6">
        <location>
            <begin position="47"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="7">
        <location>
            <begin position="147"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="204" mass="23522" checksum="D6192BD3B6BD19CB" modified="2016-11-30" version="1">MSGMYGEIALELIKELDRHKGKLPAFQENELRQALDEMQILFEQNQRDVSMNIPGNPEFLAALHLRHAALERNKQCILAYLYTRLKVITDMRWEHGPVIPANVRANMTEQEVQFFANYNKTLANYMGSLGENHGLDLTQDLKPPKTLMVEIRVLQDYGEFELEDGSSVLLKKDSVHFLPMSQCEALVQQQIVRIVEKQTSQHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8H6</accession>
    <name>A0A1D2N8H6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kunitz-type serine protease inhibitor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000147">
        <property type="protein sequence ID" value="ODN01537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8H6"/>
    <dbReference type="STRING" id="48709.A0A1D2N8H6"/>
    <dbReference type="OMA" id="RSECHDY"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF374">
        <property type="entry name" value="BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905212" evidence="4">
        <location>
            <begin position="26"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="5">
        <location>
            <begin position="29"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN01537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="88" mass="9869" checksum="D8696B963883022E" modified="2016-11-30" version="1">MKSTAFLCLVAVTVALCFLNESAEAQDSCFQGAEPGICRASIPRFYFDSRSGKCDRFTYGGCGGNNNNFRSYNECQSFRSYCLRRRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N983</accession>
    <name>A0A1D2N983_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mediator complex subunit 28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05042</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000145">
        <property type="protein sequence ID" value="ODN01655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N983"/>
    <dbReference type="STRING" id="48709.A0A1D2N983"/>
    <dbReference type="OrthoDB" id="2286203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021640">
        <property type="entry name" value="Mediator_Med28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13512">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13512:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11594">
        <property type="entry name" value="Med28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="391" mass="43031" checksum="E316BE4A2E49111F" modified="2016-11-30" version="1">MNAEITNGTGSNGFVHSNPVDKLEGAFMSCLAAITKEDTLTNVDKDEIRVDVEQGLLNFVDQARSMEGYFLKKRLEIAAQKPELIIKDDASELRFEMVRKDELLKKNYEKINVWQSILADLQSAGAQQSKNIPTGSVASVGVSLPSQGPATPGAQGPLTPSSGRPNTPGSVGRPITPVISTTGSRMHTAIRSQLIQKNPAAAVGFARILPPPSPHFSSSSMEQPRPNQDRSSLQSLLACPAPDIRIRLSEMLTRPVPETSVILNPLHTMEQQQRRNMPYLSRPACSHSHSHNMLPFQTQGETGASGTRSCHISSVMRPPSPSIMPPPPTAHFQYFYDQAGVMMTRTNVPMQLNAHANPHQYPNNCFRFRRNQSEFPNKLPSCTKDMTSRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9N8</accession>
    <name>A0A1D2N9N8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Smad nuclear-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_04711</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000132">
        <property type="protein sequence ID" value="ODN01972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9N8"/>
    <dbReference type="STRING" id="48709.A0A1D2N9N8"/>
    <dbReference type="OMA" id="WQKSCWL"/>
    <dbReference type="OrthoDB" id="444265at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22718">
        <property type="entry name" value="FHA_SNIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000008">
        <property type="entry name" value="smad nuclear-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="FHA" evidence="13">
        <location>
            <begin position="270"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="71"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN01972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="44238" checksum="ABD8364AD8D2BE93" modified="2016-11-30" version="1">MSSDWRNVRIKEEPVSDIEGNARSHRSQSRGDHRDRREGGVKRDRRDRHSPSPPPTHSKHKLKGEASGSPGRDRNRRDRSRSRDRTSREPYKGDRDRRRQPSRERRERDDADVRRIKREPRSRSRSPPRQERRRDDRDHTRDHPQPQSSRDGNERPRDGKREQDWNNFFNPNSDMSKQAVVKREKEEQERKEVLGEDFGKSEEEPPIEKEQPNFGLSGKLTEESNTFRGVVIKYAEPPEARKPNKIRWRLYPFKGEEALPVMYVHRQSAFLLGRDRKVADIPVDHPSCSKQHAVLQYRLVPYLRPDGSKGRRIKPYILDLESANGTFVNGKQIEAKRYVELFEKDVLKFGFSSREYVLLHEQSKDIQDDSPGTSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9P3</accession>
    <name>A0A1D2N9P3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ceramide synthase hyl-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_04730</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000132">
        <property type="protein sequence ID" value="ODN01980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9P3"/>
    <dbReference type="STRING" id="48709.A0A1D2N9P3"/>
    <dbReference type="OMA" id="SAKMANY"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="10">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="30142" checksum="0B15233601F61C65" modified="2016-11-30" version="1">MHSCFAVLWNKTWFMDVEECWKGYPYHSITDDVWWYNTFGGSLYCSFLMTQAFDVKRKDFWEMLIHHVITIVLMGLAWTHNLFKLGMLTLLLHDCSDVFIESAKMANYSKRDNLATGIFVVFTMVWVVTRLIIFPGKIMKSCLESPHFLALPSAPRNIITGLIIFLLCLHLFWTYFIVKVAKAALSSEKTKDARSSSESESDSEIEEEGNKGKNGLAVIQNFHSRQGTQRRHSIQYDNLVFDEIQATKRAFIKRLSVEWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9V7</accession>
    <name>A0A1D2N9V7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000136">
        <property type="protein sequence ID" value="ODN01865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9V7"/>
    <dbReference type="OrthoDB" id="7701617at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905270" evidence="2">
        <location>
            <begin position="26"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="45817" checksum="1781EA4D7EFBBD9E" modified="2016-11-30" version="1">MLFKQHLLKFFGVLILIQLCAVVTGNDEDKGRSPVSTMMKQGGKNRRPENPIRGRPCKRPKPKPVKNKNGTTKRNDDATEGRFFPGPFGWDISKFPIRLRPEKHEEPCDDDSLDSRGGDHPVDDGRPLRPHQNMHDTLEEAKCRVLLESIKNKPVERPKPGEKKNPEMWGWDVGLVLRTQESSPRRRMREHNKRVQIHRCKKRQNKNKSSSKPHRQWMAPDYAQVAQAMSEGQGGEMGDDGGASGRRIEIDPGFNIGSNRGSGMDIDPGFNIGSHRGSNRGSGIDIDPGFNIGSHRGSNRGSGIDIDPGFNIGSGIDIDPGFNRPGLTGRNIDPNFDRVPGNGIAIDPGFNIGSGGGTKVRPRYAIPSTLPAESFSDGGTAHAGTNGITSLVDRIAPELVSPHSDFCHGQKYLEIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAM1</accession>
    <name>A0A1D2NAM1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="4">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_04388</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer. The active form is probably a hexamer composed of 3 homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAM1"/>
    <dbReference type="STRING" id="48709.A0A1D2NAM1"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000011">
        <property type="entry name" value="Putative ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002320">
        <property type="entry name" value="PRK01259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="15">
        <location>
            <begin position="534"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN02299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="794" mass="89835" checksum="8F3CF383CDA13590" modified="2016-11-30" version="1">MTVDYVPPVLFYLRQGKIDVFTQDLEKSTTGTTTTTTSNNNATSSTSTTSTTPASSEENNNHRKKTEIKRRMPNVKVFSGTSNADLTRRIVDRLGIESGKVVAKKFSNRETCVEIQESVRGEDVFIVQSGSGEVNDNLMELLIMINACKIASASRVTAVIPCYPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENIMDWQNAVIVSPDAGGAKRVTSIADRLNVEFALIHKERQKANEVASMVLVGDVKDKVAILVDDMADTCGTICHAAEKLMEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDEHMKACSKIQCIDVSMMFAEAPDNIVWVEGIILNSLEENGGIEAVNKSSLAASRADNQKSDNESSHSHQSVHSTEELKISIGEIELKDESFLGDERMKPMSRIVSGKIKYFPNRHLLQLTNAAKREIAFYTQILPDIKMWIDSRYIDELIEFRVPACFYGKYLRPLDKTPDLDIISHVLDAESLLVLDDLRVYGFGKRHFGSGLIMSEALAAIEEIVKFHAVTWAMQEIDRRKLSWPELYGWQDFGNLYFNLIDNEFLSFQKFIRESNHPKAREIFFKMTKLRPHLLNKLYNLLVPAEHPFPNTLVHMDFWSENLLFRMKEEDKENNVSIHEADLDCCIIDWQMVSYGRPTHDLALLLMLSLEPDDRREHGTELLQYYYELFRKTVEYFGLQLPFDYAMLQKEFNNSCVLATLMAMASIEVVSMEESTQNRFFEALTDLMDDNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBK5</accession>
    <name>A0A1D2NBK5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Small G protein signaling modulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the RUTBC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000103">
        <property type="protein sequence ID" value="ODN02621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBK5"/>
    <dbReference type="STRING" id="48709.A0A1D2NBK5"/>
    <dbReference type="OMA" id="CDRNYAY"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15784">
        <property type="entry name" value="PH_RUTBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17687">
        <property type="entry name" value="RUN_SGSM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000004">
        <property type="entry name" value="Small G protein signaling modulator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000064">
        <property type="entry name" value="Small G protein-signaling modulator 1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037745">
        <property type="entry name" value="SGSM1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021935">
        <property type="entry name" value="SGSM1/2_RBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF502">
        <property type="entry name" value="SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12068">
        <property type="entry name" value="PH_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00593">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="5">
        <location>
            <begin position="32"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="4">
        <location>
            <begin position="645"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="517"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="704"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="517"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="750"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="765"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1072" mass="120399" checksum="194E50ED65F31616" modified="2016-11-30" version="1">MHNKALKEKLIKNVKKEVKQIMEEAVTKKFVHEESASITSLCAAVEACVSHGLKRRALGLFKSSSTTALLHKIAKAFQPAANVVQLIAEVENCDPNNEKLYVCLFLSHTNNITCSNTRLAISSRLSLSLHTNYYRRSSSSGGSESASKLGVKPPLQKRNSVATMKYLWIRLALIEKHLAKIVDYIVANSSKYYEKDALVADPDYGTILSSLLVGPCALDYSKLRTAEHFWTDPPADELVQRHRISSGQFPLPASPPAHKRPGLHYKGSTGFSNSDDNMRSKDYVESLHQNSKSTLLYGKNNVVVYMKDGSEPLAGYLSLHQCGEALLLKWTPNQLMNGCTDTGVHEKSVYWEHALNVAVHETVYVHCHQGPDSDWIALVGQDGVQRPPIHFPRGGHLLAFLSCLENGLLPHGILDPPLWSQRGKGKFTYHGVNQKKTNVSATNLLVDITSKVFPKLKRKGSSRFHSSTSPLAREESTTEDLISEKGASDFVFRIVYPNFTRTYPQVEDMLEYPVWQSSPSTPKSSIPPTTPRSTPLHSVSTTSSTSSSRSLDQQCSVQEPGEPIQVVCQTMKKQIISRAFYGWLAHCRHLRTVRTHLVGLVRSDIVKSECPTDATPGLTEEKWKELQASGSVDMKEIYRLVYFGGMAHSLRKQLWPIMLSGKLEGEDPEALRREYEDKMSEWLAVEAIVRQRDKETMAQNLAKLSSEGGNSSDPQPSPKVLQTHESNEAWRNTSIKGEPKVFVDAEETLSSEPTDGNRSQKLRSVESTTASPLKTSILSEKRAENGDVANIKASNSSNSPREKPREVSFQSDAPVFFDPSPNKHDEDDDSDVSSGEESPVATRGGVYSNEILESFGLNLHRIDKDVKRCDRNHWYFTESNLDKLRNVMCTYVWEHMEMGYVQGMCDLAAPLLVILDDEAIAYGCFRNLMERMSANFPSGGGAMDAHFANMRSLLQVLDHDLFALIRQNGDYTHFYFCYRWFLLDFKREFSYDDVFLVWETIWAARHIASADYGLFLALALLAYYRDIILANSMDFTDIIKFFNEMAERHDAKAILQIARSLVLQLQTLIENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE06</accession>
    <name>A0A1D2NE06_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE06"/>
    <dbReference type="STRING" id="48709.A0A1D2NE06"/>
    <dbReference type="OMA" id="NIGTRSM"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="530" mass="54742" checksum="47AE8272E9F1A8EA" modified="2016-11-30" version="1" fragment="single">TLAAPKLLESNIQNNTVPSPKLASSPSQLPVVPSASPIGSPMVSSPASLPPSSSPLIAAPISSPLPIHPVSSPILLSTAPSPVPKLVTSNPSSISSAVPFVPTTQSIPPPPPSVLLPKSPPPLTFPSTVGALNLLLTTPPKPVFPMSQPVPVPPPVVSERKSKSKSSRGSRGSSKSDKHSSSDLEPKPVKAPPLPPALAKSLSKKKDSSSITVPNVNLLLAGGVLPEILSQGGLGIPSALRSVVPAPVSSSSGSSSKKGSNANNSALNQPHGKTSSTSSSSRPPNSSPPPPPISQNLSPSMPIDIDRVPNPALFQGNPGIRPFHPMWVRNPGPPLPPYTTAGSPVLGKPPPLNTSSFTGQPGPPTRPGYPSPPPLRIPNPNTSPLQAFQHFKRDSPISGPLYRLQTGQPQPGVPLPNILPPGMMSPHSGGPERFFVHSLRPSGQHPQPIFGSPYDYRPPEPPFKEEPAPPPRNSSGSLPTPVSSASSSPPPTSSTVPSTTKDEASAARDSEFGGLVSYFSSQRSEEDMDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE26</accession>
    <name>A0A1D2NE26_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-selectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03158</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE26"/>
    <dbReference type="STRING" id="48709.A0A1D2NE26"/>
    <dbReference type="OMA" id="VICESRR"/>
    <dbReference type="OrthoDB" id="8950604at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21407:SF3">
        <property type="entry name" value="LD12305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21407">
        <property type="entry name" value="RE43931P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="79"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="27681" checksum="5D2D672D6DF240A1" modified="2016-11-30" version="1">MVRVHTSETILAVNFVKFAFRILTVLLVFGFFQPVHNEPKNLSLPNPALCAARKTHFRLGKSGYYATWFEKDTRNLFLNWLDARNWCRDRCMDLISMETAEEIRKVKQLMKQSNIKYCWTSGRVCDFGHGCERKDLQPIEVNGWFWSGSGAKLRPTNERSELNDWSYTGAINKPQPDNREKKNGGYAESCLAVLNNYYNDGIKWHDVACHHIKSFVCEDSPELLNYARSINKNSRVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE63</accession>
    <name>A0A1D2NE63_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein decapping 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000080">
        <property type="protein sequence ID" value="ODN03256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE63"/>
    <dbReference type="OrthoDB" id="6090360at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905430" evidence="2">
        <location>
            <begin position="24"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Lsm14-like N-terminal" evidence="3">
        <location>
            <begin position="122"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="24125" checksum="7A6BA4228F0561BF" modified="2016-11-30" version="1">MNYLNCCCLVFILSSFLLVVISASAISSQELKDPTTEEDLGSTISDTVSKRAWKNLGAAWGKRAWADMQDRGESVPTAIPDGAILKVPGGRERLGTNWIRHGESGLPIPIMADCVWSNGWLEATVQFLGKQVGVMTHSGYQYEGLLYQISDDAETISLSNVLGIETEGNNEPSGVMYNSLILRILDVYSIWSLEEEDQLHEASPPSGPGDENDDAGGSEVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE98</accession>
    <name>A0A1D2NE98_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">ER membrane protein complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03099</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EMC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE98"/>
    <dbReference type="STRING" id="48709.A0A1D2NE98"/>
    <dbReference type="OMA" id="QQTFKVI"/>
    <dbReference type="OrthoDB" id="369569at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009445">
        <property type="entry name" value="TMEM85/Emc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19315">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06417">
        <property type="entry name" value="EMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017207">
        <property type="entry name" value="UCP017207_TM-p85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="19541" checksum="E9B0CDE0C2CD4065" modified="2016-11-30" version="1">MTASTGGSKLVPKKFKWSLDYTLKHRSSNEISNPPGYNANVTHHHADTTREVDPNLIVKRSWDFALGPIKQVPMNLFLMYMAGNSISIFPIMMVGMLFMRPIKAILSLTSAFKMIEGSHHVVQKLVFVFGNVVNLALALYKCQSMGLLPTHASDWLAFVQPQERIEFYGGGVSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEB0</accession>
    <name>A0A1D2NEB0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEB0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="563"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="647" mass="71269" checksum="9FF6F9732DC9BCAA" modified="2016-11-30" version="1">MVKAREMGTSPPVASTGDERQMGGESEVGVMATETSSLSEMKHEVSETNVTLEVEAGPTDITRQHVQSSFRGSRGGGRGSRARGRGPKTTSNRSKAFSFPSTDPNPVPVDDLMQMFTMHSTVPHDVLSVPTPEINGSVGAVIVPPDSKPPQYIPREMMLRLTATINNGLVCVSHAFQLIRQSQIELEQAHHILKDIIQSQGNINQANGNTNNANISASADENGDSIASPSTPSNSTQMVVDDAPAQSWNNGSIGIKSEMAQIVNDNNVVRISNNATNGVVISSTEEMQLPVDPFEFVESHVLREADSTNQNKFGTQRGKSSRGRGGTGRRRRGGSNQRRGKASKLSILPCNYNSLMARKSPRELRGHYINNNNREEKVLEYGRFMTVAVTDIRQELGEYNEVTVFSATQVESLLQKKVQQQELQQPVQTVMNQASESDHHHSESETKKIVTKVSKKKHVSKNSNPPLEEIKTDTSRKRKLPSTSSDDDTDVNLPLWRQLRVDRNVRQKILNRIFNENEQQNNEDDDVDTSSDISSDRTEIITESSPPLSSEKMDATKRSSTDNNNNSKLNSNQQNLVPEDKDMLTYNGSSASMDCNGESAKIRTSSSSEDETDIDNVSEKEDEHPQQLGLQSTDSDTDCENDDESGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NED0</accession>
    <name>A0A1D2NED0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Glycerol kinase 5</fullName>
            <ecNumber evidence="4">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP:glycerol 3-phosphotransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_03080</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Skin-specific kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Involved in skin-specific regulation of sterol regulatory element-binding protein (SREBP) processing and lipid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NED0"/>
    <dbReference type="STRING" id="48709.A0A1D2NED0"/>
    <dbReference type="OMA" id="ECCFEPG"/>
    <dbReference type="OrthoDB" id="6278781at2759"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07793">
        <property type="entry name" value="ASKHA_NBD_FGGY_GK5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000102">
        <property type="entry name" value="Putative glycerol kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000104">
        <property type="entry name" value="putative glycerol kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037444">
        <property type="entry name" value="GK5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF68">
        <property type="entry name" value="GLYCEROL KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="8 14 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="15">
        <location>
            <begin position="3"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="16">
        <location>
            <begin position="241"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN03587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="476" mass="53614" checksum="303922FE57A82940" modified="2016-11-30" version="1">MTIRLEYPKSGWVEINPDYLWEQVIYVMKDAGISPSDIVCMSISTQRSSFLCWDENNNEPITNIITWKDRRASKLVKQWDNSLYVRAFRLVCKFLYSVTKNRRYLSGSVLKLMNELVSMRLLWVLDNIPGIREKIAMNQIKFGTLDTFLIYKLTEGEHHVTEFSNACVTGFFDPFEMGYADWALKMFSIPSSILPKLVPTCGKHFGSCKIFKGVDIPIRCCIADQSASMFGSGSFRNGSVKVTLGTGAFLDVNTGDQCRLFGGLGYFPLYGYDLAYIAEGASHNNANVIEWGKTIGLFNNVQECSDIAQSVPDSGGVYFIPAFQGLQAPYNDNSAASGFLGLTQTTKKAHLVRALLESLAFRVQQLLNVLQSETDFEFDHIKIDGGVSNNDFICQTIANLTGKRVVRPVCKEMTALGSAFMAGVNIGFWDNKECLENLYKVDKVFFPKAELEHPMLKTFAEWERALERFLKWNTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEJ2</accession>
    <name>A0A1D2NEJ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HIG1 domain family member 1A, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03033</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEJ2"/>
    <dbReference type="STRING" id="48709.A0A1D2NEJ2"/>
    <dbReference type="OMA" id="MCKELWA"/>
    <dbReference type="OrthoDB" id="10003563at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097250">
        <property type="term" value="P:mitochondrial respirasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="7">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="106" mass="11560" checksum="5FE6BA1297C6B0F9" modified="2016-11-30" version="1">MSDDKTFGFKSAYDEGQESKFIAKAKANPFVPAGIFGAVSALLYSAYKFRNRGDQKVSVYLIHTRVAAQGAVVAALTIGVGIQMYREYFLGESPQSLMKAAPKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFD4</accession>
    <name>A0A1D2NFD4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFD4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="16851" checksum="DB9081F91B6FD2D2" modified="2016-11-30" version="1">MITLPIENIRLTESKFEIINLHISVHSPNQNGGLYLVHEDESICFFHNSRKKSDGGKIVFADERSDLQGRRKEIGLAHVQFIPVSKLDCCLTTRRITEVTNKLPRMLVSALASKVEDNKMTKHSQILVNGSREMLQRYGMSKCKSIHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFN4</accession>
    <name>A0A1D2NFN4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFN4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905495" evidence="1">
        <location>
            <begin position="17"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="167" mass="19034" checksum="CDBB144B160357FE" modified="2016-11-30" version="1">MKLLLCVLVFVPFVIGEGYRRSSAGDHHVNSIAFEGSSFGGCRKKHPENRSLPGGAEACASHKPLKLKGLEKIGKRLCADGYEYCSVSHKSLHRLSWKPEIMPRTCFGFHYKKNKFAGYGHNCHRNQYFDGLLCCQSNTQKTAHNLRIQSKNSHHDRNLKHYNYVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFS0</accession>
    <name>A0A1D2NFS0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_02599</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NFS0"/>
    <dbReference type="OMA" id="SPYAIQY"/>
    <dbReference type="OrthoDB" id="103819at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009401">
        <property type="entry name" value="Med13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051139">
        <property type="entry name" value="Mediator_complx_sub13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041285">
        <property type="entry name" value="MID_MedPIWI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249:SF3">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06333">
        <property type="entry name" value="Med13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18296">
        <property type="entry name" value="MID_MedPIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0010">Activator</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MID" evidence="12">
        <location>
            <begin position="1504"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit Med13 C-terminal" evidence="11">
        <location>
            <begin position="1845"/>
            <end position="2246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="126"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="311"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="390"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="518"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="592"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="693"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="813"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="893"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="954"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1076"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1619"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2076"/>
            <end position="2132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="469"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="623"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="638"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="895"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1076"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1099"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1629"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="2118"/>
            <end position="2127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN04072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2259" mass="246181" checksum="CC7D47ACB0A78B9E" modified="2016-11-30" version="1">MNNPVPDFAFLTLFLGVMRGQQGHAKVTWRQAVALASRPFLMRLERSPNARQTASLSVSDPSASATKPEQTHPHTKPSDFQCVWRHRGERAAPGRTQQEQLTTWPPQFNHRPANDVAQFTSDQLIPTPAFTRRENELGPAAPSDTRRQRVQPHSHQAAGQGFPASLSPMTSHSQQSSLFNSTNANNSSSNANGPSLSGPKELWIFWYGEEPELSSLVHSNLLKSESEQGSWENVCMSVDVRQHPSVKRVSKQQLVVCQAPSQTVPVILAPYGLAGTLTGVGYRMSDPGTHKILEEWKQFYPVEAALKAPTYDVSTSTSTHGPHSSPHSATNGANNQQQQQQASPGVNQGAPALSSAGIPPVLEVIVGGVRMRYPSCYVLCTELDELPRSLETNSSNTSSNAPVALKTKTSPNKGVKDSETATCPAVKSPGRPQGTLTISRKVDKVEGLLPERVWQETILPSQPLAKIPSSNDQSSTLSSSEQANSANTTNICDTAGQWDFVDPTKKLGCACSKCKRPSGSKGMMSGSQSTKSGTKVKKSTFHKRSVQQLTQIEGWATHWSLTEETINSATNTNQQMVNGPIKTENQGINQQSANRVNAPPGTPVGGPPSYKTAPLGMAGEGPGASPASVAPSPLATPRSQPASVSQPEPTMPTLSPQPCSSEKPPVQTPDNGGPKSVSSLSNQVYSPAVTSFDGAKAEPTDQGNAAGGNAGNNDAPILESSAHVNNASSVTLVSGIPSGRENGLKFLKRPVLPSKEYETLLVEENANQPSETLYDYTSMEAWLNHPVKRMKASEGNSLTSMYSWGWGLRKNSDSIHGSGSEERSHSRKRKADPYEFDDENHQIPLVNLDGFKRNGIKEEEKSPFCQGESGSKGVAGNLFTNEGLQPSFRDLDQIFDNSDTSSDETFQVPTPPGSNKPANLLEDANLPSLTCTGGTKSKSGLNILRPEELSKMFPTPPSQPEHNPIASPCGLQTDNPSLEGLSDPSICIRRTQDGYPVLGSPPDDTMEVRIESNLFLKSGTQQSLRMHYQDWSYVFKPATVYKMLGSSKYSPLSTLPSQKEPPLPLSGSILLYKASWQSPPQSSTAPPATTSAPTQVQIPHPPNPVTPNIPNPLHLRPGLSPISPVPTSIRGTPFDLGSPPSNNMYLKQGPHGPNTHNSMPNHPGHHIYGSRGPEAHALVVNLSLSDSVIGLFRDHNFDSCTMCVCNANNKIIGNIRGSEMGIYVQDTSPEEEAVRCNCGFSASANRRLAHRSGLFYEDEYEITTSSLAPLALPSDEWYERKKQSLLLLDPKYTNAVALSSDRDLTAASNIVDTIPPYLLEMLKEQCILLFGSSTASRFTGEVINNGWSDWQINYLENLDANRAALIALEHGRSIMIEASGRSGYSRLPEDMIPIKNSVNLLHKWQFLWVRGPKSSQDIMNVMKALHPLLQDAVHAKAWDAQYTVSGPLTWRQFHRLAGRGTDDRCEPQPIPSILVGSEKDWLSLSPLAIRFWEKLLLEPYAYPRDVAYIVVCPDSDVIIHRVKTFFREFSSMYEVCQLGKHCPVTKVLQDGIVRVGKTAATRLASEPLDEWFSMLPDIPVASILKLYAKVCKHFLAHKLSTISLDQSLFDASYHNQNSQSRVYSQDRPTPSPKMPPPGTEPGMMPQGPPTPKTEYEAEPPKECQAQENPDDDERDPPALVVYFIEPCGFRSDNDDLHRMVSLGLLRCFASMVNGLPELIKNNITLQVLSLEDILNLGNTTLETRLKNDQMRAMALTVYSQCRRLLVHQNNVKSLTGFGPAAAAELFIKSKDEKKKGSYRLYTPPYILAPTKEKVSEGVEWLNGLQGHTVGGMVSSGLALNAGNPPLPTASSVLYVAYCLSEDQRWLLASATDERGELLETTTISIYVPNRSKRRKASARKHGLQKLMDFILGVMSTGVQPWRLVVGRLGRIGHGELESWSTLLSRKSLLRASNQLKIACHQCSLQYPADTPCVLSACLVSLEPDSCLRLMPDLFTPDERFSASGTTGSLSTPQDVSCTHILVFPTSATTQSSQTAFQEQHINGPDLGDEDLLFINVQEDMSDGIDGMQDLQLGDIFSWADTGPGAPSPVGSPRRDSASQPGSPGGIGASGRQSPFQSGGQGRTGGRGDSGEELGTLLQQPLALGYFVSTAPSGKLPNWFWSSCPQRSIENGAAVFLKSALHLHSHNILHNIDDPLQQQSNAKQHPLDSQFTTDVLRFVLEGYNALSWLCLDPVTHDRKSCLPVHIQKLLQLYYTITTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGD8</accession>
    <name>A0A1D2NGD8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_02340</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000047">
        <property type="protein sequence ID" value="ODN04328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGD8"/>
    <dbReference type="STRING" id="48709.A0A1D2NGD8"/>
    <dbReference type="OMA" id="ETESHYF"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000271">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="13"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="12">
        <location>
            <begin position="556"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN04328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="619" mass="69685" checksum="F6FA9874C1CAE375" modified="2016-11-30" version="1">MKENEFSVLEGFYLIHETIGRGGFAKVKKATHILTGERVAIKILDKAALGDDLPRVKQEIETLKFLNHPHICQMYQTFETERKIFIVMEYCQGGELFDYIVQRDRLTEVEGRRIFRQIASAVAYCHKKGVVHRDLKPENILLDSENNVKLIDFGLCANSTNCHKVELETCCGSPAYAAPELIKGERYIGTQADVWSLGVLLYALLNGFLPFDDANLGILYKKIQIGKYEEPRWLSEGSKNILRCMLQIDPKYRVSVEQLLNHTWCQEGNPDTLPLIDMDDSMNVVDNDVIRLMAANIGVLPDLLKSRLSLVNYDKYELATYFLLLRRKQKTGVQLFRRCGINIDKVLFSNNRIQKSLESEFLACDDDESIPCTPSRHVSMEGGLDDTSLLTMGSPKVVAAPEDPTDNKENIDIIDFARPRIPTPKKQKMPLPIDSAPTGIGNLSPARSADSVFTDPYKTPIRDRKIPAVQQHSPGMPSPSRRKVLGSLERGLDRMKLILTPRTSKTKKLRIIENPVKCAHNISTTASTDADAVLSELKSSLASIGIDCTQKGYRLVSKMGNAVKFELEVVMIEYLNVIGIRRKRVSGDAWHYKRIIEQVLSMTGVCQVAKKKSPLQTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGI1</accession>
    <name>A0A1D2NGI1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02314</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGI1"/>
    <dbReference type="STRING" id="48709.A0A1D2NGI1"/>
    <dbReference type="OMA" id="FCDARED"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="303" mass="32726" checksum="9A225E0B6E9DE133" modified="2016-11-30" version="1">MAGVIRKLVQNPVTFSKYLTAHSAGINSNVAAAQRLFSTGAIQFQREFVLTEKTGSKKNIGLITLNRPKALNALCDGLMKDLSDAVDEFEKDREIATLIITGQGKAFAAGADIKEMQGLTFAEVVTGGFLSHWLRVSQCRKPVIAAVNGYALGGGCELMMMCDIAYASETAKFGQPEILIGTIPGAGGTQRIIKVAGKSKAMEICLSGNQFSAAEAEKMGLVSKVLPPDQLLPESIKLAEKIGNNSKIVVGLCKEAVNRAYETTLTEGLNFERRIFHSTFATEDRQEGMSAFIEKRPPNFQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGI6</accession>
    <name>A0A1D2NGI6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="5 13">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_02618</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15842"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5 13"/>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGI6"/>
    <dbReference type="STRING" id="48709.A0A1D2NGI6"/>
    <dbReference type="OMA" id="PDEGIQM"/>
    <dbReference type="OrthoDB" id="60984at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000013">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000111">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 13" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9 13" id="KW-0521">NADP</keyword>
    <keyword evidence="10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="15">
        <location>
            <begin position="151"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="16">
        <location>
            <begin position="327"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN04076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="629" mass="70938" checksum="5E57FB97516AE472" modified="2016-11-30" version="1">MVKQNKDKGVLKLTMRAVGQTTTGELGTTSSCAAASSWVVNNTNNSHSQIKVSDSVEQDERSDSVPARDSEKAEEAAAKNCIEIPSGVPSIDSESTVLLSESQNMDTNMSASELRAQALAMIRNSLKCHEQNGHSNGTGEHLDNIPHIFTILGASGDLAKKKIYPTLWWLYRDGLLPNVTWFVGYARSKMSLADVRAKCDQYMQVKPEEQEMYEKFWELNEYVAGSYDGRRDFELLNQEIGKKEKNLSANRLFYLALPPSVFEPCTTNIRNTCMATRGWTRVIIEKPFGKDSDSSAQLSNHLASLFKEEQIYRIDHYLGKEMVQNLMTLRFGNRIFGPTWNRENVASVLISFKEPFGTFGRGGYFDEFGIIRDVMQNHLLQILSLFAMEKPPSTNPDDIRDEKVKVLKSMEALQLSDVVLGQYSGDPEGDGEAQKGYLDDPTVPAGSITPTYALAVCRINNERWDGVPFILRCGKALNERKAEVRIQYHDVPGDIFGGQAKRNELVIRVQPGEAVYVKLMTKTPGINFQLEETELDLTYNHRYKGVKLPDAYERLILDVFCGSQMHFVRSDELAQAWRIFTPLLKQIDAGQVTPIQYKYGSRGPKEADVMCDNNNFKYYGSYKWPGHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHJ5</accession>
    <name>A0A1D2NHJ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1575" mass="179148" checksum="F05C6FC4FEEFED4F" modified="2016-11-30" version="1">MLEVEFYMDQLKSDSMLNYVITIVVRKFGRTVALKEISMTERKLFELFHLIQLKAAEISQSNVSPETVLGKLYAIIRNAANMDIFKIMELPTRTKYIRTISGIPQRLQWDAEGFVGFTVEKQDCSDVLGDNQNDPTCQLEFKPVFNMETSLSLGIGYPNAKHFSQEGFILQSNLSAELPLSLRLSRSTSNKENFIELVLPPLKKAFVKGGVQVLDMEASVDSIVQWNYKISLDGAHGPSSCPYSVDTDSNPVKIVLARNFERKALSLQVSDLQYEAVVELQSDPLYSIHGNLSYSPVVGSEPIRLYHFEVGAKNSDDVKRLQMKVSKRGHESSLDVYYIRKLQSVEGAATSQAWSCRAERRTGILCSWPFCMFCGEEYFIGATISTPRWKNIQLLEGSVSQVFPDQRIDIILKTKGIHPLHKAHFKTSITRAENTSSIHSPTLRVQVEKKLNEHKINETIQTDEENGGQWSFYSLSSEVFTELYGTAGASGIFVYSRRVSRYLDIYGAELSYPSRSSQQKATFLTTMYNPNETNANVTNSYIAETTFRSTQFPILDSDSKMYSRIVNSHSKKVLYAIRLINLTKGDIKLETLNSVNKDDATNSWANFHVDQTYKLFLPEGFLHRFIKARIALERIEQVVHEAALEVSVGVGQNGLEIRYDHIPDEDNALEILTSVTTSGDTYGLHHRLEPVRDAPGIGTNGDNDAAHAESMKFKYKGTYMFEDSSMKATGIFVARSGREILPFSKFDIRVSSVDGTDLGIRIFGAEMIQPETNIQNIKMNIQKGEIKVFEFKNEINPADEVPIKGTIYLKDYGEAKFFDNTKVSNRRNLQVKVKWPSKERLIQGRISFPTSLEEPLYLDLDVLVVSEVNEETVMKNAMELKNRKWEAGLECVFVKETQNYYDKTSLKKFYRKSNYTLLTYYIPPGLQRYLVEIQSQDYSARQKESYNYLFKAGRPDVTPLHIQLGLESDEKYKVIISYTDDHPEIERSATSILNKVSSLKVCHKDNFLYIFPKLEIDLFVQNFVQMEQNYTNYHSGRNEFTNIGKVGCSSVGIYLPLCNEINMSYKFNSEHADYYEGPWVANMTIENDNKNSDIDSLNLKLQANYETVREERKTTEDNNYGDFNMVTVFLSTVRADQLMKDSYNLDYNLRSRSADGENVNTKLVNGTYVFTKMFESLDFFEFSDEHQWSQLDNGNLYIWTNLVNHTTDINQTSESATFSSQYVSLGEEESSNNITWMQLRSTLDSNGFGLLKNIILQPTAFLNTYEGTVNADFLIKTEFSPVKTFRVLLSHDHNKSENEDDESSKYDTLSKLNVILNEREISCTNSLTAADGKIVGIGNTFNGECRSVDGVYEYVTVKTFVVCPKNVLDTSEDNLVHVDVSSSWTNEDDDDTEIRISNDIIYGPTTNGVMMARLAYFENSSEVDVGRNGSIFIYQNVANMEMTRELRLTETVISDSLNVLSFTQTSLQGISQQIVDDYFNVTNLNEVQTSDTTESGQVWVDYNIDVRSNIVNQGNSSNSHFKVKWLGFEERLFHCQSFYQTCSDNGINSTDNQIDTSNYCNLAIFPAKHVLYTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHL0</accession>
    <name>A0A1D2NHL0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Heat shock factor-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer. Associates with heptad repeats of HSF1 trimers and probably also HSF1 monomers, and with HSP70. Association with HSF1 trimers and HSP70 coincides with attenuation of heat shock response and the conversion of HSF1 trimer to monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HSBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000043">
        <property type="protein sequence ID" value="ODN04456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHL0"/>
    <dbReference type="STRING" id="48709.A0A1D2NHL0"/>
    <dbReference type="OMA" id="QIVPAAW"/>
    <dbReference type="OrthoDB" id="4159489at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.430:FF:000002">
        <property type="entry name" value="Heat shock factor-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="96" mass="10544" checksum="21625F3430FAF330" modified="2016-11-30" version="1">MADLVDNMAMDKNDPNPKNLQELTQYVQGLLQNMQDKFQTMSDQILNRIDEMGNRVDDLEKNISDLMTQAGAAPYEQGTPGGGGVVTGFGIPTEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI01</accession>
    <name>A0A1D2NI01_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pituitary-specific positive transcription factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI01"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009290">
        <property type="entry name" value="Radial_spoke_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06098">
        <property type="entry name" value="Radial_spoke_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="735" mass="84616" checksum="264652DDE5DEFFFE" modified="2016-11-30" version="1">MTSLRQRNDVTLLHKGLGPGLFQYRSQPLPIYDENLNSPRSSIRSGNSRPAKKTIVKCLDRQDANSMFAKRIRERSQPQPQYITTSRKTYTSRKTQQRHRKSEAEEACDLLSKEQMFTNVAHKTSAFPPPTFMPRWNPRHRDRTYCQKRIFLDPWSLSAPDRDDLQKRTGLRLKSLSRHYQFKVGSNLPFGKEAMEKSNCLIEYCDHCNKSHFQRCPLHFNLMDPVEADCKTELGRSCPESKNPEDMNLEEINDVITYVSETERRLKAGEITETPPFPRKFLDAAFDKKPSHIVNAEESESTLNAGRRVELEDTISQTEPFRMDLDLKGFFKDNITQTVEPDSEDPKVLSLRPTIQTTFFQPFQSNDEKGTHVVQQMILGFEDAAKRVVAKVADMTMAQSLQELDDEERLRQLQKVRAMYTEQLANMHRAVSFSYMQEKFRISSYIVEEQNVQRETDEEVTGERYLGAALFAQSYLQEFTGKVMDSLRVERYIANEDLAAIQTVFIDGIGEDIANKLEVNINTNKVLDDMINHALMDLEVDYFRSYMIDEHQLETNLYTSRDLRDLIELKDDTIEMLLKIKERLIRLGWAFNADGELVRRSIVSEGSSSVGDLETFLNAVRVSLDGDGNPKYLVDLKGRPIPINANWLRRIYQQMTTNGELDPTRRFDIILGEGSLASDITEHETGAGGTTAVQEEFEGSDFTDNFELADDDEDEGRVIFHTSRSSYEFEDFEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ32</accession>
    <name>A0A1D2NJ32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Breakpoint cluster region protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ32"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ32"/>
    <dbReference type="OMA" id="PAWEEDV"/>
    <dbReference type="OrthoDB" id="2155291at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.30">
        <property type="entry name" value="Bcr-Abl oncoprotein oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037769">
        <property type="entry name" value="Abr/Bcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036481">
        <property type="entry name" value="Bcr-Abl_oncoprot_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23182">
        <property type="entry name" value="BREAKPOINT CLUSTER REGION PROTEIN BCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23182:SF1">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 1A, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="713"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="875" mass="95873" checksum="13186CE8E96CCF78" modified="2016-11-30" version="1">MSAINDFNKVWIQKFPGSELPPAWEEDVKNNLAKHKKRVQELQNELKQEEVYVQFLESLLEEVEKRKKESSAGDATGKRSSNIENHEKDIADVIKNTVERRSHISGEALSSVEDGSEKKVSSAQEFKNGDIQKDRSTNSLDSVGVADDLANMKTSDDSLSADIRGTEDDASGEDNTDDSKDHFVTVIEVNGFEKEKAAALAQSKANGNSEQLKRLKKVPPRPPPKNFKRPEPLTERPSGSTRPVSTPASVSEERKNIFEKLENPKSKTNGADAKADRPVVFDSRSTSVPNTNSNNGNNNDSNSSNSTMSSTSSKDAVPNNLSVFPRAPVSKKFEGSKMPLPPTGNNHEEKDTNKNHRKSSSTSKLLPPQHESNPSSKSSQPSSNSNSAEKPNVRSKVFDLVSKMESSRAPAVPAKSNDPLTPKRSFRKKIQDPLYCTAHDAVIADYIDPLDVEYEGVTDQIYDCPPADSPEHVSRSLDRKKGCSKTSTMESQGSCKSGEPVDTDNEPMYDTVAPDQDDDYVVLLEEQNQPTVSQNNSLSKTDSSQRKRESDYANTPIANDAAATIKSQTSVISGHSIATTTSSGTTSDADGITGSPLPQDSHSESGKTSNYVNIDYFLGKSKRKDSRASGESEDDEPVLLRAISFDQDQEGNEAADGDGIDGNVEMFDIDSGVYGSSVDSAAFGNASKSSSLGRDPHGDTPTMSAADQEKFAMFRTMVSNIAESESGYVEVLNVMLQYMKALKATLATSKPVLSTDEFNIIFYKIPELFTIHQEFLGGLQHKSSKTSVGKHFEILAKQIEVYGAFLQNYSRAADTVRKCSQSNSDFAEITRSIRLRSLNKNQAVSLETLLYSPVSRLQKNIEIIQVLNRFIRGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ34</accession>
    <name>A0A1D2NJ34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ARL14 effector protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000027">
        <property type="protein sequence ID" value="ODN05247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ34"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ34"/>
    <dbReference type="OMA" id="CALECRN"/>
    <dbReference type="OrthoDB" id="5984406at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029264">
        <property type="entry name" value="ARF7EP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46536:SF3">
        <property type="entry name" value="ARF7 EFFECTOR PROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46536">
        <property type="entry name" value="ARL14 EFFECTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14949">
        <property type="entry name" value="ARF7EP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARF7 effector protein C-terminal" evidence="2">
        <location>
            <begin position="133"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="221" mass="24747" checksum="3E21D62D25EA2167" modified="2016-11-30" version="1">MEQEDNVNIERMEVDEEIVLRNSSTECPVPVDAALPSSLMSIATSDTLPSVVNQVSSALNVGGESEVSVNSDPSSLPPPNDLEDSRQVVGDKSASTVSDMENNDQQTNTDESKNNSSSCPGEKRLGHSSRKYLQKDEMKFMANFNPSQRMERKRLKKYTEFGVVIERCDCLIPTCPGCFLPCKICKSTRCGHQCREGRLWDYEEIEVQGRNIFRRLTDAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ67</accession>
    <name>A0A1D2NJ67_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ67"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="12463" checksum="61076CBC8BF3173C" modified="2016-11-30" version="1">MQFSSTLDNVVNMDQNQANQQPKEEAESGDVVNQNADATSSNTNNTTSQFHNSPRKESAEYVEDVLESFSQTSQGAGILLTIEDSDALANKLAAAAAEPMFEFGEIQDAPNDYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLF6</accession>
    <name>A0A1D2NLF6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphofurin acidic cluster sorting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_00578</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PACS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLF6"/>
    <dbReference type="STRING" id="48709.A0A1D2NLF6"/>
    <dbReference type="OMA" id="AKNQNTM"/>
    <dbReference type="OrthoDB" id="28829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019381">
        <property type="entry name" value="PACS1/2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057541">
        <property type="entry name" value="PACS1/2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13280:SF17">
        <property type="entry name" value="KRUEPPEL TARGET AT 95D, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13280">
        <property type="entry name" value="PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25332">
        <property type="entry name" value="C2_PACS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10254">
        <property type="entry name" value="Pacs-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphofurin acidic cluster sorting protein 1/2 N-terminal C2" evidence="5">
        <location>
            <begin position="29"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofurin acidic cluster sorting protein 1/2 C-terminal" evidence="4">
        <location>
            <begin position="361"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN06094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="713" mass="79253" checksum="D58C5A2B91E14B28" modified="2016-11-30" version="1">MNSFQAPDRPRYNTCEFNSVEPNVDNVLSSRLCSLTLIRLVVMRPLPTSEVSSVIVAVKMAGSRRTLRSNEIPLTDNGLINTDLELHFSLQYPHFLKRDENRLLIMLQRRKKYKNRTILGYKTLAEGTIDMAMVLQRSYLDLELNLFTPDGGNKENNGPLAKVTIMGIASQPVDDLEDRKGKHNSGKPRNPAHDFSDDEDDFSSHSSDSPPDDVILRKNSKLPHNRNLKQKIVNLLKKFKATEEGHRGSEAKTGGAIDNIDNIDELFDELEGLSDSEPDADTLSVGSFPKPVLPPFFASSHSIPEKSNLTSDERPDSDSFTEPDQHSGESPKLSVRSPGTSPCVGIFSPVTTTKAKVISIADQLAKAFPPDDRFLDLIVLVSVENQGGGVFSALDKSGIRVLGIESDADLKQVLPHIVAKVQKFCNNNAKAPPPITIAVAGTDAFLSGTAKHYVTQLSSRPHDWQNYFSFLYAPFITGGSIWRLLCQRDTLYGQTFTDQLEREPSEEMALRIISYANVAKERRQIVNVPIAEAMITFKENEESSQVFVPFISEVRLNVGYSSVSIEQQQDPGDLSSSPPSPPHSPREEPLELQVDFWKGTIKSSVKASFRSLTIQRTSDNALALSYTLKEQKKQKIMRLGKKKERDSDVKNQCTDGISRLVCLAKSQTPIKLFVDGAEWPGVKFFQVSAQWQSQVKTLPLLLADPSKIDSIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLL7</accession>
    <name>A0A1D2NLL7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PDF receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00543</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLL7"/>
    <dbReference type="STRING" id="48709.A0A1D2NLL7"/>
    <dbReference type="OrthoDB" id="5967113at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050332">
        <property type="entry name" value="GPCR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620:SF17">
        <property type="entry name" value="PDF RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620">
        <property type="entry name" value="PDF RECEPTOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="16949" checksum="943A071C9D2D1E70" modified="2016-11-30" version="1">MKTLRNSRTRLHRHLFIAVVIQVAIRLTVYTDQLITRGIEVDGEVTTQDNNHLAHSHRGIDNTPYLCEASYISLEYARTAMFMWMFVEGLYLHNMITGYLPPPYFWWNIRPHEYLVFQFPFLRKNFHRVFTKWWGGLYLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLW8</accession>
    <name>A0A1D2NLW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLW8"/>
    <dbReference type="STRING" id="48709.A0A1D2NLW8"/>
    <dbReference type="OMA" id="EEARCTC"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052384">
        <property type="entry name" value="TMTC_O-mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216:SF3">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="22057" checksum="F8ED280FBB261F4A" modified="2016-11-30" version="1">MVAVYNSLGEALYRNGQPEEAEQWFIKALRTKPDHVPAHLTYGKMLARNTRLLEAESWFRRAKKIAPADSSVYHHYGQFLSVQGRHSEAAESYVTAANLAPTDYDIIVGAANALRLSGDNTQAELYYKKAEARAHMNYGAILHVNGKYTEATKSYLTALRLKPEDDVTLMNLKKVMAISKSSKSLVLISCQHNKDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLZ0</accession>
    <name>A0A1D2NLZ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000008">
        <property type="protein sequence ID" value="ODN06272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLZ0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="13460" checksum="DB32D489A4ADDBFA" modified="2016-11-30" version="1">MFQRKNPGPGLLVSLPPSSESSVVTIKTELPPPNHPGDGGDNYVGLPPAKRIRHESSNNDWGDSESSPGGHINASQGFTFTSPPGSLDDPYSPHIGKPTLNFMCFHFHNFTKPEPDMCSVSRSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMB6</accession>
    <name>A0A1D2NMB6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Tachykinin-like peptide receptor 99D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_00277</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMB6"/>
    <dbReference type="STRING" id="48709.A0A1D2NMB6"/>
    <dbReference type="OMA" id="SILYACP"/>
    <dbReference type="OrthoDB" id="5981855at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004995">
        <property type="term" value="F:tachykinin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15390">
        <property type="entry name" value="7tmA_TACR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000291">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001681">
        <property type="entry name" value="Neurokn_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46925">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46925:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00244">
        <property type="entry name" value="NEUROKININR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="9 10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905763" evidence="12">
        <location>
            <begin position="26"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="168"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN06402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="520" mass="59351" checksum="98AD21606CBDEC77" modified="2016-11-30" version="1">MDFVNTTLLLLLAAAVGQTRWFVSAEGATYTFDESPLSNNRAAGFHQGPHQNHPPSLFSLSTTSSYLMESRWQYAPDDDDDNGKNHYGNNNINYNNNSTFGLMTGLTVMGGNESMESSFGGTAGANGTESEEMDEDEEGAAFQAAVPWWRQIIWSILFGAMVVVACTGNVTVIWIVLAHKRMRTVTNYLLVNLSIADAMSSTLNVIPNYSYMLTGHWPFGALYCKIVQFVSMLSICASVFSLMAIAFDRYMAIMNPLRPRMGKRLTLGIAAAIWIGGTILSMPMLVFFQTYEKIISNGETIVICYSEWPDGPQTQSFQEYLYNVFFMIFTYFIPIAVMGYTYTRVGIELWGSKSIGECTQRQLDNIKSKRRVVKMMIVVVTIFAFCWLPFHMYFILVSLSPNLTNYQFVQEVYLGIYWLAMSNSMYNPIIYCWMNNRFRRGFQQVFRWCPFVHYSEVEGTTAYMMHTQRERETTRYSVTGSPEYNSTRVSRNGLSVKSNFEKPPCPNVFHRTHHKDYQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN88</accession>
    <name>A0A1D2NN88_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_00031</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Toroid-shaped homodecamer, composed of two pentamers of five dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NN88"/>
    <dbReference type="STRING" id="48709.A0A1D2NN88"/>
    <dbReference type="OMA" id="HFACRPQ"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046148">
        <property type="term" value="P:pigment biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="12">
        <location>
            <begin position="91"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN06679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="271" mass="30167" checksum="A0A1F6CC6B8C0B3D" modified="2016-11-30" version="1">MSTSAGAGEVRNGVNKPSPITIDPLVLKKKLGKMRDLSNGHSCENGCSTDLESPRTPRTVATPGHEKCSFHHDLELDHKPPTREDLIPNMASAYRELLGSLGEDPDRQGLLKTPERAAKAMLFFTKGYDQTLEEVLNDAVFDEDTDEMVVVKDIEMFSMCEHHLVPFFGKVSIGYLPNKKVLGLSKLARIVEVYSRRLQVQERLTKQIAEAVLKAIEPRGVAVVCEGAHMCMVMRGVQKINSKTVTSSMLGEFRENAKTREEFLTFCTSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNB8</accession>
    <name>A0A1D2NNB8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Receptor-mediated endocytosis protein 6 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_00249</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in endocytosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GAPVD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NNB8"/>
    <dbReference type="OMA" id="ENHEIML"/>
    <dbReference type="OrthoDB" id="10264848at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051049">
        <property type="term" value="P:regulation of transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.80:FF:000001">
        <property type="entry name" value="GTPase-activating protein and VPS9 domain-containing protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="10">
        <location>
            <begin position="172"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="VPS9" evidence="11">
        <location>
            <begin position="1323"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="565"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="818"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="914"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1003"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="575"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="585"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="613"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="635"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="831"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="916"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1014"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1042"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1086"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00053914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN06436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1462" mass="160528" checksum="7602962E6EF3BEB0" modified="2016-11-30" version="1">MPSSNFDLIDLCRRLKQEKLFVANERKEIEGLNRKVQLLSTGLLHQTWLTGQHRLALENMSNGPVTSPFTCPFVVSPADGSGDVTENLELVQAHKLISGRYLHNYIDLITLLRNHPEIVALCLSLYEKDRGSQQRMSGTPNVGFGDILQGVINVYGGIGGPLPGDGTSHLKLLSALAGHQLVGTESPRRVLRQGSCAFSFLYRLISETTPSSRLFLVGALHQPVTELLSSPNLLCLGTNIPATSPSASMDTAGCIPTSGQNKDILSLDRTEKMAELTKLFIDSILDNINSFPPGLAWLIKSVHVQLSPNYPEKEVSTICTDLIWALFICPAVTNPEPFGVTDAPVGSQARHTLSQVATNLQALALHRWEGTDPRLQEYIAYLDPESLTAVLDHVLSIDSLPGEQSGVVASLSRRTLLIPENLMHALFTWLKHCLPLVEQQGKLKNLEVWMALEKLTLSVNESLNSLASAPKTSNSTPTSSVSGSNPSLSSSGSPSHGARLLESGRKALMNRRGDARVSSNQQLSDARSDSPLSVVVFPTTQSAWEWVGMLPESEVVSASKNGKIANSVPDVEGLPADDPEEEEREERSSLGEKRTRFSLSHDDGSIGTSDNLEAVSEAASTHSVSSSIELEDQNDNLSDMLSANVSGRGTPNVSGRNTPLSQAEQEENENDAELDDDIIMNEVPNEPPPNNLNPPNLNNLNLNGPDKQARSEIEDKFCKFEIKKQFEGDETVSLVSDTWSTDVLASDSEMGGDIQPAFNLPFNQVNAMPRQQPAPVPIVPAQPAELLPAAQPTHDNQNNETMSEAWSTDVAASDIGRLNDFDTDDASSVARSDDTGRSELDGMAYDTPRSSVSGGVAYRPRSSRDRDNEPDLLMFDDVPRRDEPMNVVEAQLNPVAPVDAAPVPMEMSVEVPVPSTSAASNMTPSNSQGSLLNDSQGPSTSAQLTVGGTSNSLLAPGSSNRSGAIPKTISFDKTAERGDRENWDEDNGRNSTKRFFRNFRLPFRGRNRKPNSRTGDDRLIDWDRMPENPSLPVPKLRKSLSEDPTNPVVSNETSDDILAKYRRKPSLTDATDAANPNIASRDQANSSKSSSVAGASSTAVVRKDSLKMSRSEIIVDARKKLRNVLSNCDLQVQAMDGNSIDVALTNLLRIEMASAISRADQVTAAHLQDAVRTVKQIGGDGCRKVMRLMRDDYRRRSDYISYLMRAKQGLLSTIQFLERATVRAKYEGDTYSHYLINECIRIWLEEPNQSQYVEQFTIEFCQATAIDEKIELLEGFLSTLTDMFVGTKELSEWQIGKTENALEQYIVTRVYVHALYPNGDGDKDRDRLLRDHIAKLDLVITPSHRDLRIPKSRLGECPWPPAQRELKMLSAYKTPSDKLRCIIKACSVIVNLLSSSSEKVVAADDFVPVLVFVLIKSNPPALLSTIQYVNSYCGQRITGEEGYWWTQFCSAVEFIKTMDYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0P0</accession>
    <name>A0A1D2M0P0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_20158</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01008475">
        <property type="protein sequence ID" value="ODM86524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0P0"/>
    <dbReference type="STRING" id="48709.A0A1D2M0P0"/>
    <dbReference type="OMA" id="HYNNAFI"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="8">
        <location>
            <begin position="30"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM86524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="20247" checksum="F1522F2BAD99CEBE" modified="2016-11-30" version="1">MQVMMLCSAANDILAAEDRAQVLKISPCLKNKRVLELGSGIGRFTTELAKLAKKVTAVDFIESYVEKNREVNGHFKNVSFEAADVMELELTDNSDEEVEKLTVKMLGWLSDGGYLFIRESCYRPSGDVKRTTNPTYYRSPIDYFKISQNKIYNTKWRQPFSFVCQRALSIEAYIKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2U3</accession>
    <name>A0A1D2M2U3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005667">
        <property type="protein sequence ID" value="ODM87289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2U3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="57" mass="5818" checksum="CED1E51C5B194234" modified="2016-11-30" version="1" fragment="single">MQSSSSSSSSAFSKSWSAVTTLLVYGAQQQSQPAANRAAVSVCGLCSKTTASPAFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3Y3</accession>
    <name>A0A1D2M3Y3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_19034</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004913">
        <property type="protein sequence ID" value="ODM87644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3Y3"/>
    <dbReference type="STRING" id="48709.A0A1D2M3Y3"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050752">
        <property type="entry name" value="C2H2-ZF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24384:SF189">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24384">
        <property type="entry name" value="FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM87644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="30442" checksum="2F17D6A5FD4E23DD" modified="2016-11-30" version="1">MSKFTLGSVHLNVKYATSRLTQMVPLSGTKALVLHFLHLQEKPYECVHCKVSFKTRPALNSHIRPHHAVRQSIALSLEAYSCPMCDRTFSTTSLCDHIRRHVRERLFPCHRCSKEFVRSNDRKDSRENIYSSIQPPCTHSDPCSRKMVRLRGLREGIRNLNWTSSTLKNHSNTKSFLCPFCGDGFNRSESLNYHIRRHIGENPHSRSSCLKDFGNAVALRQHLCEMQPYVPLMNNALKANIQKKALRKLNIHNQYLSLVDRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4X6</accession>
    <name>A0A1D2M4X6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc finger and SCAN domain-containing protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004319">
        <property type="protein sequence ID" value="ODM87961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4X6"/>
    <dbReference type="OrthoDB" id="3561125at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="348"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="114"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="437" mass="50092" checksum="44B1EA379C80CB5F" modified="2016-11-30" version="1">MSLATVPCLFCASPCSPVFTTIDGRLTRLKSEVPGATGSLSSSSLCFLETEENSLLAQQLQVIFILRDILKLKDDKITQFLGKLDGGFNPEFWIRLCQSCESAVKDYFVTLNKVNRLQKKLLRISEELKVKIEETEEAHQDSEEEDDAEKISRHVWKEIREETLLNLTEPEVESPPKSSNFQNEQIRGRILVEGDIRVEFDEKDGSVRLDVPDLSSLRQILGLENDSSQKVTIQEKPSSSLQAETHSSPPQSHPPSPSYDKNWRRTLTCDDCPYFSKSPLYFDAHRELHQPGSSFVICTICGWFLNPKNLKMHIAKRHPKSVVKTQPKRRYRTKPRKKQSTTPKRSVCKCSECGALFHNLLIFKHHQKLHEKGEGVNCSECGWLILASKLVSHTKYWHPEEENKKAELRRRVENYSIREIGGKMGRKTKNLDQTEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M537</accession>
    <name>A0A1D2M537_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">COBW domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004123">
        <property type="protein sequence ID" value="ODM88097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M537"/>
    <dbReference type="STRING" id="48709.A0A1D2M537"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF31">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="2">
        <location>
            <begin position="59"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11167" checksum="0D832953C21B6701" modified="2016-11-30" version="1">MSRNGTTDIDDEEDEEVPELVPLEEASQFQPFGGENGEGESSSGGVELEEGVQRRGPVPVTILTGYLGAGKTTLLNYILHEQNEKKIAVILNEFGTGAGGNLDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M628</accession>
    <name>A0A1D2M628_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003685">
        <property type="protein sequence ID" value="ODM88371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M628"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="28611" checksum="C122EF69FEE7A9D0" modified="2016-11-30" version="1">MDVNFQLRLRTHSADPNGGEHGTGDNAPDVDGRSDDTIHFGSLWSICWTLLWQLFLARTPGWRSPVCCGCSLLWAYQNGSSDQPEVCPWRLLSWGCLPLSIIFHCGLWIPAPSLGHSHQYFGIGPVDPPPKAAGSRLSKVTFAVPEAITKMFDVSPASPPSRPEDSDNMSPLARRVTRSSPKDLYTLPSLISLPAPEDFTAPRLPDLKVELVNDAARPGSKALKLDERDSISTVEMEMNQMLPSSQLICYPNYAVIARIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6V6</accession>
    <name>A0A1D2M6V6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polypeptide N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="13">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Protein-UDP acetylgalactosaminyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_18029</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Golgi apparatus membrane</location>
            <topology evidence="2 13">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="13"/>
    <dbReference type="EMBL" id="LJIJ01003340">
        <property type="protein sequence ID" value="ODM88654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6V6"/>
    <dbReference type="STRING" id="48709.A0A1D2M6V6"/>
    <dbReference type="OMA" id="DLKFHPD"/>
    <dbReference type="OrthoDB" id="416652at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02510">
        <property type="entry name" value="pp-GalNAc-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000053">
        <property type="entry name" value="Polypeptide N-acetylgalactosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045885">
        <property type="entry name" value="GalNAc-T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF43">
        <property type="entry name" value="POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 13" id="KW-0430">Lectin</keyword>
    <keyword evidence="12 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="14">
        <location>
            <begin position="519"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM88654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="653" mass="75522" checksum="AB76FA05553B5573" modified="2016-11-30" version="1">MLNSCFAFIARRRRLFLLKLLAIFCFVMTLLLWSKSQVKPETSTVVEGSEKLVGIKMERTDQLKAPYHNKLKVTEKGSPNLSNGYNAAEDTELRRKVLLENTDEFLEPVLKEVKYVEIDLTDRMTNSYDDYDDEIEDDIKRVKPGLGDKGKKATVPSYQKAVADNIMKKEAFNRLLSEMISPNRSVPDTREAACKNEVYDQDLPTMSVIIIYTNEAFTSLVRTLHSVINRTPSKFLREIVLVDDFSDHRDLKGKLERYIAKKFPAGKIRLIKLSKRSGLIRARMIGAHVAVGDVLLFLDAHCETIDQWAEPLLQRIKEDRTAVVCPIIDVIDDKTMEYYHGNGEFFQIGGFTWSGHFTWINIPSYEAERKKHHHSPTRSPTMAGGLFGIDRKYFWEIGSYDSDMQLWGGENLEMSFRIWQCGGSVEIIPCSRVGHIFRDFHPYSFPNNVDSHGLNTARLAEAWMDDFKELFYSHRKELKTASWGDVAKRLAFRKRKNCKSFKWFLDNIYKEKFQMTFDSKLYGQVKNPDSNQCLDNMQHSESDEYSLELYPCHTQLYPSQLFLLSNKGELRREAECASLGNDDKVQMVQCEHLHAKDVWDYRDGQLYNMRSEKCLTVKVVDGKSHIVLETCGGTPNQQWEFDAHKDKDEDNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7M8</accession>
    <name>A0A1D2M7M8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_17757</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003057">
        <property type="protein sequence ID" value="ODM88924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7M8"/>
    <dbReference type="STRING" id="48709.A0A1D2M7M8"/>
    <dbReference type="OMA" id="LLWFMNA"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903577" evidence="16">
        <location>
            <begin position="23"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM88924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="463" mass="53280" checksum="2904CD5725C5CA61" modified="2016-11-30" version="1">MILVVNILILVIFLLVWWFVQDKRSYKNYPPGPPRMPILGNILQIASQSSFPSVAFLNLSKKYGDVMFLKMGMVEAVTFNSPDSVHEILHHEKAIDRTRTMLPLIQARMYGKNLGLIFSSGESWQKLRHFTIRTLKDFGFGKAASMDVVVLEEMDKFVGYLETKMQRDGVVEVDGLFNLTLVNMLWRLVTGINYSMNDKKIQKLLKLSNDMIKNTKFSFDASATFPFLWHLFPSWSGKNLQMMNITALQEYCRETLEYHRRNCDYKNHPESYVDVFLQKIDETRKNPESEFTDDQLVLCLLDLFQAGAETSSQTLSFSMLYMLIHQDIQGKVQKEIDEVVGKGEVITLDMKSRLPYTQAAVLECLRKSMVAPFPAARQATDDFYFRDYFIKKGTIIMPNLECVHLDRGIWGDPHNFRPERFLNKDMSIDTKLAGKMLLFGGGKRVCLAQSLAETTIFLVLQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7V0</accession>
    <name>A0A1D2M7V0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein phosphatase CPPED1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002942">
        <property type="protein sequence ID" value="ODM89056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7V0"/>
    <dbReference type="STRING" id="48709.A0A1D2M7V0"/>
    <dbReference type="OMA" id="NEESWEG"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051918">
        <property type="entry name" value="STPP_CPPED1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="34958" checksum="44D46E0198CCFBBB" modified="2016-11-30" version="1">MDFKIPEGLPGMNIKKWLKDPSELGSCKLKTSKPTWKAEIELTRQAIQKINSLSPKPKFFMICGDMLDAYPFEKSSIPFYNGNDRVIRDLQYKDFVQVFKELDPEIKLVFACGNHDIGDIPTSQSVEQYRNQFGIDYFAFWVGGVKFVVLNSQYFYSSDALPEEHEKHLDFVNKIADPTAKYIVIFQHIPFFAKDPDEDDTFHSIRKERRLKLLELLWNAGVRYVFCGHHHKNGGGKYKDLEQVVTSAIGAPWGKDPSGFRLVQVGPLDITHKYIKLRETTDCLEFAKYEKSSAQTDNGNVIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7W1</accession>
    <name>A0A1D2M7W1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_17679</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01002985">
        <property type="protein sequence ID" value="ODM89004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7W1"/>
    <dbReference type="STRING" id="48709.A0A1D2M7W1"/>
    <dbReference type="OMA" id="NATERWG"/>
    <dbReference type="OrthoDB" id="6672926at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="7">
        <location>
            <begin position="3"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="8">
        <location>
            <begin position="309"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM89004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="400" mass="44259" checksum="76A8ECFC675CD63E" modified="2016-11-30" version="1">MDAPLVTTKTIELINFEKLPAGQNAIICVMSYSGYDIEDALVLNKASLDRGYGRCLGYGPLVDSASGKPVWKHEWLDSDGFAVPGACMENKQVLVNKSMPTVTQVGASGYDDATRKKPVEFRETPVIHRGPVPSYVEKVMLSSNNEESYICKLLLRQTRRPEVGDKFSSRHGQKGVTGLIANQEDMPFSDTGICPDIIMNPHGYPSRMLIELLAGKAGLLDGCQHYGTAFGGSRVEDIGEDLIRHGYNYEGKDFFYSGITGEPLVGYIYSGPVYYQKLKHMVMDKMHARARGPRAVLTRQPTEGRAREGGLRLGEMERDCLIGYGASNLLVERLMLSSDAFNVDVCNSCGLMGYSGWCQGCKSSMNVYPIKIPYACKLLFQELQSMNIVPRLELKQMGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M877</accession>
    <name>A0A1D2M877_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-mRNA-processing-splicing factor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002844">
        <property type="protein sequence ID" value="ODM89165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M877"/>
    <dbReference type="STRING" id="48709.A0A1D2M877"/>
    <dbReference type="OMA" id="ERIPLCT"/>
    <dbReference type="OrthoDB" id="1699641at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012591">
        <property type="entry name" value="PRO8NT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012592">
        <property type="entry name" value="PROCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRO8NT" evidence="2">
        <location>
            <begin position="107"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="PROCN" evidence="3">
        <location>
            <begin position="401"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM89165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="615" mass="72385" checksum="40B3DD67088B7B5E" modified="2016-11-30" version="1" fragment="single">MSFPPPYMIPPPPGMPPGMPPPPGGGQHFYQMQQHQQQVMEQGSAIDFHDIAPPGTTPFDPEAMRAPGTYDNELTEDQKQEKALKWQQLQTKRYADKRKFGFVDTQKEDMPPEHVRKIIRDHGDMSSRKYRHDKRVYLGALKYMPHAILKLLENMPMPWEQIRDVKVLYHITGAISFVNEIPWVIEPVYIAQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQIELDGDEDAPVAEWFYDHKPLSDTKFVNGPTYKRWHLELPMMATLYRLANQLLTDLVDDNYFYLFDLKAFFTAKALNMAIPGGPKFEPLVKDNSQLYHTPNVVFIKTEDPDLPAFYFDPLINPISHRHAVKSLEDNFDESDDFELEYVEPLLSSLPLYSDNTANGIALLWSPRPYNMRSGRTRRSLDIPLVKTWYKEHCPPGQPVKVRVSYQKLLKYYVLNALKHRPPKPQKKRYLFRSFKATKFFQCTTLDWVETGLQVCRQGYNMLNLLIHRQELELPAFDYNFNLKPVKTLTTKERKKSRFGNAFHLCREILRLTKLIVDAHVQYRLNNVDAFQLSDGMQYIFAHVGQLTGMYRYKYKLMKQIRMCKDLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8Y1</accession>
    <name>A0A1D2M8Y1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ viral recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002648">
        <property type="protein sequence ID" value="ODM89430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8Y1"/>
    <dbReference type="OMA" id="NEWHLER"/>
    <dbReference type="OrthoDB" id="6155932at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22343">
        <property type="entry name" value="PDDEXK_lambda_exonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051703">
        <property type="entry name" value="NF-kappa-B_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46609">
        <property type="entry name" value="EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46609:SF8">
        <property type="entry name" value="YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ viral recombinase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="26152" checksum="4F508E25941D9C72" modified="2016-11-30" version="1" fragment="single">AGRGDENYGTDPDRPDLNEEMLQEEMDSIRRAVTVDKERQQEIQISTLGQSNCEIWGRERRKRLTASNAKRICSMQDSTDNHAVLRQLLSQTEFSNEATIYGNTNEAVAADKYAEDEVKMCGLFVSLEHGGLAVSPDRLVEHDGLLEVKCNNGCNISIMDWAKERKSECSLIIKDGALTMKTEHAHYYQVAMQIFVTERQWCDYFIWSPTGDYFLQRVTRESTSHCGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9N0</accession>
    <name>A0A1D2M9N0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidyl-prolyl cis-trans isomerase FKBP8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_17051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002488">
        <property type="protein sequence ID" value="ODM89632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9N0"/>
    <dbReference type="STRING" id="48709.A0A1D2M9N0"/>
    <dbReference type="OMA" id="ICVASMK"/>
    <dbReference type="OrthoDB" id="532682at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF1">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="110"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="281"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM89632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="391" mass="43570" checksum="5426822217F320F2" modified="2016-11-30" version="1">MSANDDLKGEPPVEVETSPDPHSNGGGGDADMFESKADKSQASASEDQSSISEKANELKEHDVPDEESAQAEKVKHELQKELEENDGWLKILGNDEIMKKVNKPGLPETRPLRGEVCTIRVEGRLQSDESVIFESHDRFSFQLGDVEVITGLDMSIPLMCKVELINFENEKDLAELTVSERRETGNRKRERGNWWYGRGESSLAIQCYRRALEFLDEAEGGIQYPSASSPEKLKVSDELKALFDDRIKTLNNMAQAQLKLQAYEPALNSVDAVLKCQPNNVKALFRKGKILGEKGSTEKALEILRAASSLEPDNKAILQEIAQLTQRQKKEHHSEKLLYKRMFKDSSDKSSETKSDNDKGTSYKSAFTMGLVLTGVAAAAAGVLAYRYRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAQ0</accession>
    <name>A0A1D2MAQ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_16673</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002239">
        <property type="protein sequence ID" value="ODM90009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAQ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MAQ0"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903722" evidence="2">
        <location>
            <begin position="25"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="152"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM90009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="31163" checksum="C6D0E5E739B346AE" modified="2016-11-30" version="1" fragment="single">MTKLNFSAVAITLLAIQLTNFVQCEEIVLSDDNGSAFTLTITGGCYSLNPKWSQRATEAEVTDGCFKAYDFANCKGKAVELRKGVHDLRSLNFDKEISSVRLCTPIEEDAEQGGKAKPTPESGRSTTTGRGPGRGSSSARTERPRGGGAETEAQKAAVMEHNKYRKMHGVPDVQGDPQMHAEAQRYADYLAQSNLFEPSRTGKYDVVKRWYDKNKFYDYERPGYNIDGRNSGSFTAIVWKATTHIGLGIAWNEVEEQWIVVAFYDPPAMRSKFRENVLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBV0</accession>
    <name>A0A1D2MBV0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipopolysaccharide-induced tumor necrosis factor-alpha factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001966">
        <property type="protein sequence ID" value="ODM90443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBV0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="2">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10288" checksum="261A1D0852F4AB07" modified="2016-11-30" version="1">MSESAPVSTTETHNLPHVGPSSVRMTCFGCSREILTNIEKSWSSTAYCCTIWSICCCGIFAICIIPACMDSESWWTTKHTCPHCKVHLGTHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MES6</accession>
    <name>A0A1D2MES6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Signal transducer and transcription activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_15167</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transcription factor STAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001526">
        <property type="protein sequence ID" value="ODM91516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MES6"/>
    <dbReference type="STRING" id="48709.A0A1D2MES6"/>
    <dbReference type="OrthoDB" id="7993183at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.630">
        <property type="entry name" value="STAT transcription factor, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001217">
        <property type="entry name" value="STAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048988">
        <property type="entry name" value="STAT_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013801">
        <property type="entry name" value="STAT_TF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012345">
        <property type="entry name" value="STAT_TF_DNA-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11801">
        <property type="entry name" value="SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02864">
        <property type="entry name" value="STAT_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21354">
        <property type="entry name" value="STAT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SH2" evidence="14">
        <location>
            <begin position="709"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="454"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="841"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="844"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM91516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="887" mass="101880" checksum="78E18669F843B1DA" modified="2016-11-30" version="1" fragment="single">SPIRHCNLRRESIQRFLSRVFEGFSITVGLREIPTEKNLIQESALEVFRIVYVSDPRLLFLRVTFADWVEDSILKISPVNFVRGLTFQINKKLLKLNSGSPVELHSFINRLGKYKFELSKFDGSAMEELHSKFIKCFDEELKLGQRCVFQFPSESLCIVNKVEDMQQDVGVITFCQEIQNAVGNCRARVYNVMPKLMEEKKQLIDLIGNLRTSIIHFEDWYKYFGNYHQPEQGHVHEQLQLLMFPTSEVRSEIAQLYQDEGRKILTIKEEMKSRFQETLNTCLIFIQDMQNFLRCHQRVQQIRANGADVDPTTVVDIQEIRMLVSQILGFIIEMSPVLQSALDTFDVNRIRLCNEHPHYIQCYELLSINAFETNFETCKREFEKLEVRIYQKFSLIVSQQPEQVIKTDRANPISVTLFNFNNVLSSPIALQAYLINEPVAKSIIDGLPEKLETAGTLSQTDPNSPEGSESGGRKRRRRSDNVTPTSCRNPKYSSIHSSNLHLGVKQPGKFSGLSINTGLRAEHMTFSSDRTYFNIQLPLTITHVERKKYGQGKTGQKDNSENVTKEKFCFLFVAELPVRNQIVKVWTTSLPMIVTTHGSHNEKAWATIAWDNARPAVGRIGFEIQPTATWWQISEMLQGTFKAWVGVPLKTSHVEFIKNKLKVHIGHTFPNEISWGELCEDKMDDCEFSFWCWFYRAAMIVKGHFKEPWLNGYIEGFISWEAASALLIRSKSKPGTFLIRFSDSEPGSLSLVFLANDGKTYRMLPLEVYKNKSFEDCCVPFLEQLNVRERQRGKDVFRWVYPNICKKLAFEKFYNQPKDNIAKLKPHYVLVLCVVPTDKEAESSSETSDTSEVSDQTKNTTETTVPLTPTAVSVELPVGVESISGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEW5</accession>
    <name>A0A1D2MEW5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001513">
        <property type="protein sequence ID" value="ODM91538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEW5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903916" evidence="1">
        <location>
            <begin position="22"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="11349" checksum="01584547BA4CB3A1" modified="2016-11-30" version="1">MTLSKRALVFLLIIGTSSISGNNLYLCIQGDMTKPPEACMPNATLCMDTQSRSYAQLTCTDTTLKLSCCGSLCLCCPSGPGLPSGGCACGQCKYPIATHVDQDIFATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFS2</accession>
    <name>A0A1D2MFS2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase TIC 32, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001407">
        <property type="protein sequence ID" value="ODM91825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFS2"/>
    <dbReference type="STRING" id="48709.A0A1D2MFS2"/>
    <dbReference type="OMA" id="FTWFRYA"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="343" mass="38447" checksum="07DC1D37FED91DDB" modified="2016-11-30" version="1">MGRNNEITPPGSLQERFVSFIWYGVIMAGWLGLISFLDEAFHTVKKFNYEAIPKRKGEVVVLTGGTRGIGFDILKNLLQMDYHVIMGVRKIEAGLAAVETIRKSGVKSGTTQCLPLDLKSLTSVRKFGETILKEKDRVDILLNNAGIMFEPYELTEDGFESHFQVNYLSHFLLTQILLPKLKSTGAKKSTCCRIVNVSSVAHTASAIRNVKELASPKWGFRNMYSGFRAYYDSKLCQVLSTKYLDARLKLEGTNVHVYAVHPGVIPTGLYSSIGIFGQIMHWLAKFYRNSDEGAEIVMYAAISPEIESEGGLYMQNSEKRAPNKIAEDHTIQKTLWELSETCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFX9</accession>
    <name>A0A1D2MFX9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein sleepless</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001388">
        <property type="protein sequence ID" value="ODM91879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFX9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903968" description="Protein sleepless" evidence="1">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15495" checksum="A9F2575EC3BFC3FF" modified="2016-11-30" version="1">MKTVLLILVSFTSFLAITQGLECYNCYYQDSSLPIGFNPKLTEHPSCQRGSVPDESLKVDCSEVHFGSSEGENVTYTSSKKGDGTAFKEECLDGKLGKVTLQSTVPEITTILEQEAEMFNSFFTDTHVCNCNDELCNRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGA9</accession>
    <name>A0A1D2MGA9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein Mo25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001376">
        <property type="protein sequence ID" value="ODM91941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGA9"/>
    <dbReference type="STRING" id="48709.A0A1D2MGA9"/>
    <dbReference type="OMA" id="AYDHKES"/>
    <dbReference type="OrthoDB" id="609103at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000025">
        <property type="entry name" value="Calcium-binding protein 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="38890" checksum="1C6D89C60A9AD95B" modified="2016-11-30" version="1">MPLFGKSQKNPAEVVKALKEAVTALERGDKKAEKAQEEVSKQLTNVKSILFGAADTEQQTEILIAQLSQELYNSNLLLLLINNLSRIEFEGKKDVAQIFNNILRRHIGARSPTVEYICTKPEILFTLISGYEHHDIALNCGTMLRECARYEALAKIVLYSDDFYKFFNYVEVSTFDIASDAFSTFKELLTRHKLLSAEFLEANYDKVFSHYQQLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISNPDNLKLMMNMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQEKLIDFLTKFHEDRSEDEQFNDEKAYLIKQIKELKPSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGH7</accession>
    <name>A0A1D2MGH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001354">
        <property type="protein sequence ID" value="ODM92011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGH7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.15.10">
        <property type="entry name" value="Proaerolysin, chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903986" evidence="1">
        <location>
            <begin position="20"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="630" mass="71597" checksum="F8B1A5F27E995A85" modified="2016-11-30" version="1">MALFRYLMVFASLFNTILAGTEVELFSLPNFDGGVNTAYVPNVGCMDVAVGGGSLRFGGGGCMIAYQDKDCKVGGFVIWTEFYDLPKLSQQYYSGVPSFKLRSLRECSDMELRSTVDVDFFEGDIGSGGKKIEIRNLNNCTPVPLFTDWNDGLHNIVSYGKCVKLYKSKYCLGPPDPYYMNVIPSQFTKDLGYLSMEPCHEGTLDFFTEKNFKGIRWQTYLRYFGIAENFPIDFVALSMKTTVCTRLKASPWLDDLTYVINSEEKDLQNLPFKYKSYPGGLVPYIFTHVDTCDSIYETGPTYNVELWYWHNKEHTETPYYNLCRCQEIPEKAQGYNTVIYGYGKCFNVYTTKNCRGAPDSVRHSYAIYKQHEEDDPWLSLEPCSIDAAVSCLRIHARVFSMERISSTHDFAGTRADFAMAATQTFYNDGFGTIEKAIKVSKEVTQTASMEYTEGFRHMHTFQYTFTSTATFEAEIPLLGTAGGSISHQLSTNNEWEYTYNNVSKTETSTKETFTIEETLIIKPCMKYEVSSTVRMTKNAAMTFTQWFEITGRTGTNKKLTIQEIKLYVEKNSPDIIIIPGHEKENKYTLVGQSTVVLTYDYNTEVILTATGEPLPACIERHKDSISLWNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH66</accession>
    <name>A0A1D2MH66_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001258">
        <property type="protein sequence ID" value="ODM92347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH66"/>
    <dbReference type="STRING" id="48709.A0A1D2MH66"/>
    <dbReference type="OrthoDB" id="6779941at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="267" mass="29324" checksum="0644D739569B510B" modified="2016-11-30" version="1">MPSGKENFGESLYGVTGGNRVSGQKRVGFNICDNSSTQSSSSPKKLEDPPQHFLQDLQRVMQKKWQVAQKCNADKNTTPHEILGFRVEPANGQENDVLPPPMPVMEELNVKQMHPAVIPTSPSYHNNHAPCQSAAPTPVINSNLNNVEAWVSQHYGTIMGNMGKMPQSNNRPSPPPVGQKPAPPQRVASYMSTSSSNSSNAIYQQVNHIPMSHNSSSNSVVIYENFEGRKSANSKQYPGVELRQKRPPPPVPKRADSTHLSAHIVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHA0</accession>
    <name>A0A1D2MHA0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Ras GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14294</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001245">
        <property type="protein sequence ID" value="ODM92387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHA0"/>
    <dbReference type="STRING" id="48709.A0A1D2MHA0"/>
    <dbReference type="OrthoDB" id="5572587at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04013">
        <property type="entry name" value="C2_SynGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05136">
        <property type="entry name" value="RasGAP_DAB2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF60">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN RASKOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="40"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="4">
        <location>
            <begin position="228"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="616" mass="69377" checksum="A6B9B13D995AD6A4" modified="2016-11-30" version="1" fragment="single">WRRVNPTPSSIILGQEHAFQVTTPTGPNTTRVHRQLSETPGSTPFVKQSGLGDEVRRRENSLKIWILEGKGIPGGSSGKNSSKRYFCELYLDDVLYSRTCGKPRGDMLFWGEHFEFTQLPNCVQLITVVFFREGDKKRKKERNTCIGKVKIPVNTVTSRYLIEKWYPVLPDSSSSSSKEKEHPSLRVKCKYQSVDILPLRCYKSFLQYVKDQYGPLSECLESVLSVKAKEDLASAMVHVLHHENLAKEFIAELALQEILKSGDEKLTFRGNSIATKAMEAFLKLTGTEYLHATLGPFIEQFQGSEDLYDCEIDPMKLPAGTNLSKNQQNLRMAVDTVWKAIMHSHSIFPMELRECFSHCREALKSAGKEELSDHLISASIFLRFLCPAILSPSLFNITNEYPSEKSARNLTLIAKVLQTLANFTRFQGKENYMEFINDFVEREASNMKAFLSCISSPLSPEAVKKVQKENRDKVPAGGFIDLGKYLSILSALLSENVAKIAPKNDRFKQLQELLETIHKWLEQPANATNVSMFPFPHLPSPPPSGPPPPAPLGIPMNHRFSNPLCNNNNSQAINHQYQIPHHIVNAATTPIYAVSSVIHNNSNPNVKNISQVQMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHB2</accession>
    <name>A0A1D2MHB2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001242">
        <property type="protein sequence ID" value="ODM92397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHB2"/>
    <dbReference type="STRING" id="48709.A0A1D2MHB2"/>
    <dbReference type="OrthoDB" id="5519333at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027861">
        <property type="entry name" value="TMEM249"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35442:SF1">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT TMEM249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35442">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15158">
        <property type="entry name" value="TMEM249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="308" mass="35936" checksum="566D8966102EC1D1" modified="2016-11-30" version="1">MRRRRRTWKEKWRLWHLGAVERYYFEQKENTTHPFEDLGDGFYYITVRSDKFLFGVGLITTTVTCFTLFCLFVGFYGFPLALFLVTFSYGVFSMYGNLSTKELIISRNGGYLMRFKGTTKPLVEEPIHNCYIKLQRKYDANKLPHYYLILGGFRLDDIRITGSGAHDGALRLLGSRLAARMGINYFDYDNNSTLHQIIHYPGFTTLKHTDEEYTKFLQEHKISDDDVARALIEENLPQDTSIAPERIVRRIKENYKAGQLQEVDEGDKRSRRNVISKRDITSLKRTVQLLQNLRRFAGPTKSTNPVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI59</accession>
    <name>A0A1D2MI59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Angiotensin-converting enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14028</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001178">
        <property type="protein sequence ID" value="ODM92653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI59"/>
    <dbReference type="STRING" id="48709.A0A1D2MI59"/>
    <dbReference type="OrthoDB" id="10029630at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008241">
        <property type="term" value="F:peptidyl-dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001548">
        <property type="entry name" value="Peptidase_M2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10514">
        <property type="entry name" value="ANGIOTENSIN-CONVERTING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10514:SF27">
        <property type="entry name" value="ANGIOTENSIN-CONVERTING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01401">
        <property type="entry name" value="Peptidase_M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52011">
        <property type="entry name" value="PEPTIDASE_M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="12141" checksum="7B811A1E1F055DA9" modified="2016-11-30" version="1">MRLTYLWSAWRNATGRKIRNMYNQFVDLGNDAAKLNDFDSLKELWLRDYEAPNFQKNCEELLRQVKPLYDELHAYTRYMLREKVYPQLKPEDPIPEHIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIT9</accession>
    <name>A0A1D2MIT9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_13766</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001119">
        <property type="protein sequence ID" value="ODM92920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIT9"/>
    <dbReference type="STRING" id="48709.A0A1D2MIT9"/>
    <dbReference type="OMA" id="CDMTDEM"/>
    <dbReference type="OrthoDB" id="6506078at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21453">
        <property type="entry name" value="DLC-like_DNAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000002">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF2">
        <property type="entry name" value="DYNEIN AXONEMAL LIGHT CHAIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 12" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00057688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM92920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="12253" checksum="351C0D62BD862AA4" modified="2016-11-30" version="1">MADAETEAKKDDGEGEKKFGQYPLIRMTDLPNETKPEIVEMISATVERNSMDLQNACKLIKEHMDKTYGSSWNVIIGEAFGFEVSYLKRHLLYMFTLGTLGVLVWKCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ86</accession>
    <name>A0A1D2MJ86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001074">
        <property type="protein sequence ID" value="ODM93106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ86"/>
    <dbReference type="OrthoDB" id="10678501at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="508" mass="57376" checksum="97C9699351EA0E18" modified="2016-11-30" version="1" fragment="single">ILLGIANSVYLYRPSVLLKRSLLRRRLLHMPINGTLRLKRQLFREDIPHHRPLSGNTYYLHAGFPHPSRWYDGPQTILPNPNPITHHHLQHHGHDFSHDNGQDHHHHNQHQNNELQHQAHPPPAPIIIEHLDKNKHPLSVTIQSAVVHNNGVIDNSIVNTPPPPPGGSHTIYGRPLGHVRNSPRKKRPPKPHSDPEPHYDDYNHGPGDYDIPSKDYGPPPPSHHHHHPPPATVTEHLNPIVTKKPKTVIHYHPVQVGNIINFNEDHKPLRESYGSPNHETYGPPSHESYGPPKHIPGIPLAHKDVMMNMAEPFLKSPFKSVNGEPAYLSFSNSGPGIGPGPGPEYGPPNHQPGAPLDALSIAPLVPSYGPPIKHDPIPPYGVALPVLAHFHSGALSHPPQHHPPPKRHRGRHQHHLHHYHHVHHHPPLHSGGGESPFFDVKYPTYVVHGHAPKKFPFHSPHYRSRPHKFYHWGCKTISDDDDDNMTMTKRPTFNVMMLYSVLAYMCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJM1</accession>
    <name>A0A1D2MJM1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13457</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001043">
        <property type="protein sequence ID" value="ODM93227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJM1"/>
    <dbReference type="STRING" id="48709.A0A1D2MJM1"/>
    <dbReference type="OMA" id="KHVSVTY"/>
    <dbReference type="OrthoDB" id="2248014at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF35">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="4">
        <location>
            <begin position="175"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="374"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1213" mass="133251" checksum="807A075C6E100698" modified="2016-11-30" version="1">MTLRSSPYPKESAVLTMGQAIQEAEVAKIKEMDSGSSTMPSSATSFVSDGSEDAGFEDGPIDVDVDMNDEETEGIQIDCIQTLTEFDSLPDSDPNFKESSGSPIMSDCKTAIPLPAPPLSIGSAYGGNQAYNSFQSIIPRTDRPTSPITSYWNDIPYSGSSAGENRDPSRAPGDVGLNNIGNTCFMNSGLQCLLHTSPLVEFFVESDTFEKTISSLVYQFHSLMKHAWFGYAGAISLHDFKLVLGNKYAQFKDCRQHDCQEFLAVLLDILHEELKLKQKAHSADSSVGESYIEDCSSALSPHPDQSVCSTSKDKETSVIGSSSETENDTVTKSSTSSTSANTLNSSESVCSVDELDHCSHDVKRKSAVGIRYETGVSENNEAEESVKEAPESNEVDESVNDKTGNEAEVPESNEVDENVQDGNGNEAEGSQQEILSPVQKAQEYWEKYMKENNTVVASTFQGMFKSAVTCSECSFISETFEPFMYLSLPIPRVMEKQLSVTFISMKDRCPVKVDLTLHLMGSVEKLIQETVKKVDSTVWDDRSKYAAAEVLNYRVARVLDEKQQLRNLSTNNRNIYVFELNDNFDEKYGSFPVSDNPYKYGATGMSVSSSADQGLASTSLHEDWETDDTCPQIGTVVSTSNSSTYGDLRAPVGGGAYDGSSCAFGPSVSSSSDTPVQDNDNFNRVQCNICLEDYPKSDLKQHVGCSCVLCEECLMKSVDHYKTSEPGDKGKAGTYIKCAVCLQTVECKRAFLSLEELSTSTSPTEFITMPILFKKEPGTDANNNAAWSSGLFGYPWLIRVPSHMNASELVEYVESIIPAPDVTHRLLSVKSDAKNCGQCVYSSRCDGCEIPREGMISLNSCNSILISYTDLSSDRMSEMQPSDMSIQNELNWQHNRNEEPTIDIHDCLRTFSETEHLDEQNPWYCPRCKKNQRATKALSICKFPDYLIVYLKRFVFMDQSSNKLNNRLTFPVNDLDVSDYVTEGFGSNLGKYDLYSCVCHFGSASSGHYTAFARNPVTNQWHYFNDNTISERTPAEAEYASAYVLFYEKQGMVCNIPSKCSGPLPELNSFNSMTSTSYTGGDTRGSYLPDDPIPAGPVRMDGDFINEVNLQVDSTSPSFTFPHVATEADLLAIDVDEGVGNETSQMTDIRETDADELSFSEHDSLVVTSTSTADDGIKHLDEALGLVDPLATQDHELSSSCTCTGSADSTSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKT2</accession>
    <name>A0A1D2MKT2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000941">
        <property type="protein sequence ID" value="ODM93639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKT2"/>
    <dbReference type="OMA" id="ATRNNEC"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="209" mass="23842" checksum="F5D03780B8B0BD5D" modified="2016-11-30" version="1">MSYLPALKCYQCISLECPQKQLFCDSVKEYILNQLPELYYGYEGQRVSICPPPDEKDPGWEELRRDTKIDCEEVKDDEATCVLGRYRVTTEILDSGKNITSHGTAMGCAKRSLLQMTKAAVAKNECDMSKSVSRFKHSLRHHLEIEHCARPPDMCHKNDFCIPPHATEIKEFHEEEPKKPFPFTLILGVFLLIALAVIVLTFLAPFFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML68</accession>
    <name>A0A1D2ML68_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000917">
        <property type="protein sequence ID" value="ODM93776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML68"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="730" mass="82092" checksum="540FF94D4B8D569E" modified="2016-11-30" version="1">MSHSKRFPAPSRRVLIRPGCGGHQAAMMATGRTRTAYSSAMSDCWNNGSSSSRTSTSNSTRLAQAYIKTSCLFCSKVVMLAGLHPEPARVITRRQKNLQNLCFHFKLNGKELPTNATKIQFPFCTTCEKYVKELTVLQETLEKVKLEIDKTVNSIERIVADTEVLGNRGQPSPIERQKFIKLYDMILEGYRNKLMIRHQINNSMTPESAPIETGDLSPNPMENREHRATGIEMEEEYDETIEIFMDSHEVRVDHDEELSNTTDVNHQDYYQGESYANVWNMEDPREVSRSNENDCTLVITSVQSVAAVGTGTPDGDNRDGVSSIANVEVIDLVELDNEAMASPDEEEDEDADNASLANVTADAEQPQSFLFEDVQSVQKSQPVGPHRKEATLSCDICEKAVRGALIHLLRHKFTHKNDEERRESLRKKERGCYNAFLSKKLTIAYKRKQNIGAGNGSSSPLTAKRMNLYLLENHSTSIRFRRGSTSNVIGVANFFLVTMKCRRLGRFQTLCLLQYNKIIREGRNCNPSYLVTQVGGDIDEIFKYVFSTSVSSSRFSLKLNGSLRPYFEKMTAVHGRNGGFKFLASCKINKSAANGFEIAFGNQSTPIQHRLNLSEEGLKALLDFVYCLKLDIPREKPSVALELLDIGIKKQMPMLTKAINSLLVEQPDDWFGFDAALQLFLHSTKMQGYDELKKKAVRKGDEMESSELCDQLLRTDPKSSKMLMKALSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLP3</accession>
    <name>A0A1D2MLP3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase II subunit RPB11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">DNA-directed RNA polymerase II subunit J</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12697</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000875">
        <property type="protein sequence ID" value="ODM93989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLP3"/>
    <dbReference type="STRING" id="48709.A0A1D2MLP3"/>
    <dbReference type="OrthoDB" id="10248581at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06926">
        <property type="entry name" value="RNAP_II_RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037685">
        <property type="entry name" value="RBP11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF16">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="10">
        <location>
            <begin position="31"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00067485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="14392" checksum="5748E475F9F8BAB9" modified="2016-11-30" version="1">MNAPASFESFILFPEEKKIIIEPETKVPNAAMITIQKEDHTLGNMIRCQLLKDPHVLFSGYKQTHPLEHKIVIRIQTTPEYTPAEALKTALKDLLEEVRHLEDRFKVGAMQLINNKHWMFVIDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLX9</accession>
    <name>A0A1D2MLX9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative leucine aminopeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12622</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000867">
        <property type="protein sequence ID" value="ODM94050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLX9"/>
    <dbReference type="STRING" id="48709.A0A1D2MLX9"/>
    <dbReference type="OMA" id="QPFSEFH"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904235" evidence="9">
        <location>
            <begin position="20"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="157"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="407" mass="45556" checksum="10D8EFC983136D14" modified="2016-11-30" version="1">MKTLQVLLIASFGVLLASTVPLGQHGKRRLIKVSEFEPPKWLNDKEIWGLLEKDIHFMDITDIKNFSEKKPEISQNKGIPTELKYEALVSQAFGSINLGRIETFIQTFSDFHNRYYDAENGVISQRWLLEQVKSSIRDYAGNVSVIEIEHDWLQNSIIARIDGADPTLRSQVVILGAHQDSINTNGITLRAPGADDNASGCITVLETLRAIVQNGIIPNRTVEFHWYAGEERGLLGSLDIAQRYKEANVQVFAMVNLTSWARKIANGESGTDYLVAFSNVSLIWERSGSKGLSKLVEYYVDGNDDIAIVTDYVDNELTQFLRVLIDGYLSFGRRERECGYACSDHAAWTQNGFPAARPTQAVRNGQMHTLNDTIGTVSFIQVREFVKLATGFLVELADVSRVVFTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMA3</accession>
    <name>A0A1D2MMA3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Salivary plasminogen activator gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000848">
        <property type="protein sequence ID" value="ODM94180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMA3"/>
    <dbReference type="STRING" id="48709.A0A1D2MMA3"/>
    <dbReference type="OMA" id="IRIHEAF"/>
    <dbReference type="OrthoDB" id="6656697at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF143">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="1">
        <location>
            <begin position="127"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="40261" checksum="7D1E9DE2DAFBED38" modified="2016-11-30" version="1">MLNELVKLSHGQAPNFIVFHLFHLSRGGIQPITTTPPITIITPSPATTSNSVVIINPTTPCQCTATANCADGSGTLNPRIVNNNPPVVCAVGQVYCCNLINPNPVTAAPTTIPPSTCGIRPNIANTFLPGVGQAAYAAYPWTALIFRVSDNALIGTGVLLDANTVLTAAHKVSPATQVLRVRLGEYIINAVTEPNPLVEIAVSAIRIHEAFNSVNLVNDIAVLKLATAIDFNFNPHIRSICLPAVGAVYSGQRYQLDSKLWGRCWTAGFGASSFASNQYQTTMREVDVPILDGPTCQARFSASRLGATFVFNQQSFICAGGETSRDACTGDGGAGLVCLTGTQWFLAGLVSWGLDCGQTNVPGAYVNIPNYLAWITTNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MME6</accession>
    <name>A0A1D2MME6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory-associated protein of mTOR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000858">
        <property type="protein sequence ID" value="ODM94118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MME6"/>
    <dbReference type="OrthoDB" id="10262360at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="4">
        <location>
            <begin position="71"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="783"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="855"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1035"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="861"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1392" mass="155822" checksum="C3548C9887C988B7" modified="2016-11-30" version="1">MHKVVEKEQACNLNMASMDRVMELNFRSTDEESYFQESHDWVLPHVFQDARHVEKIQGQDVPPQGWRMKERMKTVSVALVLCLNVGVDPPGLIKLQPCARFECWVDPLSLSPQKALENIGQNLQKQYERWQPRARYKQSLDPTVDEVKKLCVSLRRNAKEERVLFHYNGHGVPCPTTNGEVWVFNRNYTQYIPLSVYDLQTWMGYPSIYVYDCNNAGVIIKSFHQFAEQHEREYYSEAGVNDRGGAGDTTRSSTPPPPNYASCIQLGACSDKQVLPMNPDLPADLFTACLTTPIRMALRWFVLQNQCNAGIDRKVGFNKLLSDGITLETVEKVPGQLNDRRTMLGELNWIFTAITDTIAWNILPRALFQKLFRQDLLVASLFRNFLLAERIMRSYDCTPVSSPKLPPTSHHPMWHAWDYALDQCLSQLRKQDAPVEQFVHIPSPFFEEQLTAFEVWLTLGNEKRNPPEQLPIVLQVLLSQVHRVRALELLGKFLDLGWWAVNLALSVGIFPYVLKLLQSSAKELRPLLVFIWAKILAVDQTCQTDLVRDGSHKYFIQMVGDNTLSYEYRGELPGQQGSLVSLALEETPAQSTQSISNLHKWVCICLGLTWQDFQRAVWGSRLCSRKLPLFERREGCSVFALGSFVNGMERTEHSNSIDHSVVLMILNKLADNEASSLVRQELVVALHNFVLVFENHFVSVCEKQLAQQQELYCAGLGIMSPINLRRISSNSARMRALAAAGNSNLTITGAEAYGSNAAGGDSMRRVASSSSLSNLTAVGLPSSALQSPREAPSPSSSTVQGTSSVGGIYTRVWASLLAYERDPHQGVSILARSVIEYIKSKAYAKTQSLNKSFQTRELESSTEALSKTSSTASTPTRTTQPPLLSTPVPITPVIATRYINWCWSQFSKPCNTVEVVDPQDPAVYTRAWVYSKNAKVRRDCFKRVKNFPGKIEEQVVSKNLNDVLRPGMNTTVSFHPYENLVVVGGGFLLDGGSAPGSVSGSLSSLNVTGLGQSVVVDKSVFLVFEYDDTTHLSSLNMSTSSHRRRRRPTSSNPQSPFQVQPRVINRTEIEHVTERVRAVQSSDNEWLNPHDSIVTRTCSLLAAGCNDACVRVYKPCVESKTSVLVTAWSLGNTNRVNNLLMKYEHEQQRLVVSYHGARNTNVGVWDLGSERMVREIGGAVSDKLKSDNVGSSIDFWVTCLDAHRCGQFQFYSCVFDENSHVKMQKITLISEPNVFVIGGEDGSVRLLDLRVPPSECVTTTWRDFNANSSIQNVRLRHDRSVVAGCSNGRVRFFDLRSKSPTKTIDTTVDVTVLDIHPNLPYFAIGTASSTVNVYGFHGQTAFLSNSIREGFGGFGRIGLANNSISCVAFHEFKPFVSFLDSYGHFSVYKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMH4</accession>
    <name>A0A1D2MMH4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000865">
        <property type="protein sequence ID" value="ODM94071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMH4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="8417" checksum="27413E76D4C1DB44" modified="2016-11-30" version="1">MCARSLFLPDLEMLSLRGLGRDITDVTCRFAFEEMHRLKYIELGGDTSITQKGRLCLHTRMRDRGCKVNFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMY8</accession>
    <name>A0A1D2MMY8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipopolysaccharide-induced tumor necrosis factor-alpha factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12483</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Lysosome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CDIP1/LITAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000844">
        <property type="protein sequence ID" value="ODM94194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMY8"/>
    <dbReference type="STRING" id="48709.A0A1D2MMY8"/>
    <dbReference type="OMA" id="ICKFTIG"/>
    <dbReference type="OrthoDB" id="5599753at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037519">
        <property type="entry name" value="LITAF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292:SF6">
        <property type="entry name" value="FI16602P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292">
        <property type="entry name" value="LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="10">
        <location>
            <begin position="52"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="147" mass="16064" checksum="8807C18810E1789F" modified="2016-11-30" version="1">MSAPPLYPDPSELPQKAYPPPYDAGMQQGAAPPPGLYYPPVQASPNLMMAGQPPQVVIPCYLPLGSHKASITCRHCQNEIQTNVDRKPSRVAWFYASCLCFAGCVCGCCLIPFCMDSCMDTHHACPNCGAHLGTYHGEWKMGFNWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNE9</accession>
    <name>A0A1D2MNE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha-mannosidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000814">
        <property type="protein sequence ID" value="ODM94381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNE9"/>
    <dbReference type="STRING" id="48709.A0A1D2MNE9"/>
    <dbReference type="OrthoDB" id="10261055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050843">
        <property type="entry name" value="Glycosyl_Hydrlase_38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607:SF70">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="267" mass="30726" checksum="A6EB307F8D090750" modified="2016-11-30" version="1">MQLGKLCKSCRPSPLEVSLRRNDKENSFLATVLDGLNPTLFEFLLKLHLLVFMERQESQCLHRLIPNWEQRKMAILEYLMDTMTIANCRNESGAQLYVVSGPVMQEVTVLCKDLTISAYILLQGYTEALSAVYLTNSVKPQGTKFGEFFMSFQTDLETREKSFNDDSLEPTFFTDTGIAVEKRMKVSRLPYEGKYVPCNKLCLYPRRTGGTRFSFWWIVHGFTSTKSGQLEAIFDRRLPYDDARVLDEGVNDPEDMVSNYVLLQNPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNK1</accession>
    <name>A0A1D2MNK1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000781">
        <property type="protein sequence ID" value="ODM94617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNK1"/>
    <dbReference type="OrthoDB" id="10501698at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="191" mass="21922" checksum="9D69A56F7998F271" modified="2016-11-30" version="1">MAGGDRDPWKNRKTVRICSAIDMVFPIVIMGLYMYRLMFERKVDGRMTNGFYTPKEKQGVAVFLWCGAFTLNIIQFILAYNLSTVVKLGSRDADVSLRGLKFWLILANFLFVLLLSEFIFFLFFDKGYYGHRKTVSMIVCAAELFFKPIGMYFAKEFIDDLKSVYAPPTAKVQFMSFLSSVRKPQGQTGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPJ3</accession>
    <name>A0A1D2MPJ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000730">
        <property type="protein sequence ID" value="ODM94953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPJ3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="116" mass="12645" checksum="C55ECFB0448C80F8" modified="2016-11-30" version="1">MLEKETTILYKDIEYVSHRRGRRVGSSEVWVTDRALFLSEFRGGSWGGGAGGGGGGGRGGGGGGARYSNTRRRQQAFDLVSVVYLMYHVLCPLKHIISLPLLEFEVFGTTGLETFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPL8</accession>
    <name>A0A1D2MPL8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UDP-glucuronosyltransferase 2A3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11966</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000763">
        <property type="protein sequence ID" value="ODM94715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPL8"/>
    <dbReference type="STRING" id="48709.A0A1D2MPL8"/>
    <dbReference type="OMA" id="NWIMIAG"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000050">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904337" evidence="5">
        <location>
            <begin position="23"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="481"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="529" mass="60053" checksum="8059D14E91D2C671" modified="2016-11-30" version="1">MDSIGILFLAGFLSFAAIPASSDRILFLMPIATKSETHLLIPLVKQMLDKGNEVTFVSPAVSGIQHKNLTEIIPVTPLTMAEFLPVDGDVLDIRRAKDDKTAIISVDMSYMYDRCHATYQHKDFEPILKSQPGSFQLVVTSAFFSECFLGLIHQMQAPFIVLCSMALPQHINDVTGLRTPLSFVPSPFIPMTDKMTLSERLENTFSSWMFSLLSYHHFFKVSENIYKQYLGDDLPDVETLRKNVSLIFSNTHFSLNFPRPLMPDVIEIGGVHCHHPANPLPKDLEDFVSGDKNGFIFFSLGTVFREETMNDGLMKTFINVFSRLKLRVLWKWGSGNIEGLSSNVKVSKWLPQKDLLGHPNIKLFISHGGLLSTQEATYHGVPVLGIPLFVDQDINMKQAEAHGYALKLELLDITEEYLENAINRMLNNSSFTTNAKLASEIFRHQPQNPLERAVFWMDYVIKYKGAPHLRSSARDLSYIEYYLYDVQLIIISILGTIVLIVWKIISCILQRSSREGDDSKKIRRRKKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPS1</accession>
    <name>A0A1D2MPS1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polypeptide N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Protein-UDP acetylgalactosaminyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_11674</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000722">
        <property type="protein sequence ID" value="ODM95006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPS1"/>
    <dbReference type="STRING" id="48709.A0A1D2MPS1"/>
    <dbReference type="OMA" id="NVPMGSI"/>
    <dbReference type="OrthoDB" id="429263at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23434">
        <property type="entry name" value="beta-trefoil_Ricin_GALNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02510">
        <property type="entry name" value="pp-GalNAc-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045885">
        <property type="entry name" value="GalNAc-T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF119">
        <property type="entry name" value="POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4 10" id="KW-0430">Lectin</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="12">
        <location>
            <begin position="406"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM95006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="529" mass="59446" checksum="8D03AC5BCA2F2205" modified="2016-11-30" version="1">MNGALDIKVRSTSTPSSRGGQNLPSKVINGYSSSSLSSNYKSPGGSSTWVTNNRGQDSHSSTHHQQQTGYSSGVVTDPFESFDQEVYLHGDKVLRGQDAYGKTKFNQVASDNLPIDRSIPDTRHPMCRKREYDVPHLQPTSVIITFHNEARSTLLRTIASVLNRSPVHLIHEIILVDDASPNADDGALLAQIHKVKVLRNHKREGLMRSRVRGADEATAPILTFLDSHCECNEGWLEPLLQLVTFNRTHVVSPVIDVINMDDFRYVAASAELRGGFDWNLVFKWEYLSPTERREFARDPTQVIRFRVWQCGGTLEIVPCSRVGHVFRKQHPYSFPGGSGAVFAKNTRRAAEVWMDEYKNFYYAKVPLAKAVPFGNIDDRMAIRDRLKCKPFKWYLKNVYPDLKIPQAAMYPSGALQQGHRCIDTMGRSAYHTAQVYQCHGEGGNQEWSLTKSGLIQHDEICLSMPTSLYVGAPVVLTPCEDASKWYYSKDKLIQSQDKPGFCISASADSSNLVSAICDPDDYLQKFEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS54</accession>
    <name>A0A1D2MS54_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000641">
        <property type="protein sequence ID" value="ODM95634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS54"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904455" evidence="2">
        <location>
            <begin position="26"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="835" mass="93673" checksum="5C78023BDBE380EE" modified="2016-11-30" version="1">MFTNWHQFICMLVVGASITILEISAEHDVPHVTQNFYDPHYHDDGRNHLRISKAISGPTAASSASTMSILHPYAANSESGPSTPPIMAIVDHYYGPNGEEKVQYSSPSSMDKDELEQVLGNLRSAKSQFRLTSSPYHSVSHSPPHSHTKFHVPQQPPPPVKYNSVSSYKPSTSLPASSSGYSLSSLYKSAETYSKPSSAPTYRPAFSTIYKDQSNQQPKGKKYRSKEHVYTASKDSLYSPSYHKHKEPILLHSPKEPAYVEDSSFYNDAPKSISDSILFDSGYKKGYPPKSLMSNAENYKPPTSYYSPSHPTSYVPPPPHHRHHACGGGSSVEYSPYMTSGKLYSPGIVIKEENSYGEGSLKAGFHSLPMKHSSHGQTAEYSYTSPHHESYSSGFGGGYSIEATSDPYSRPSIKSYPSTSRPSSNHIGHSLSSLYEPLTYDDVYSHTPKSSSYGASLANLYAPGGGISHSKPSYGPPSAYTMSYGAPVEYHMASPPPTGHVSSSGPYSSPSLPTSSKYKGPYRLVSTGPSGYGYGKSHSAGNLFSNYLSDMFSWYKTRGGGWARRPPMMQMKPYYKYKYSTISNSNIHKHPFELENGPSEKHYRRRNRFSHNDQQSLRAVSSEHTKHSDDGITIDKDVYEDEVQPKPKIPPQSHSYHPYSHHSDDDEQDQIPKPSPIHRRPHEPKHNSYKKSKMHYHSKNNQHEAPQTRHIRPSPRPNIQTESSEVLDIHVFEKGFFDGQKKPRDNEWVPVTRHPYGEGGHGSASMERDTHERGHRIKGGRVMRHSRRPPPSRRKTSRSNSRPYHNSRPDDDFESKHHRQNSNEEDLYYDGHSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS70</accession>
    <name>A0A1D2MS70_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein flightless-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000614">
        <property type="protein sequence ID" value="ODM95846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS70"/>
    <dbReference type="STRING" id="48709.A0A1D2MS70"/>
    <dbReference type="OrthoDB" id="20529at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051014">
        <property type="term" value="P:actin filament severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008154">
        <property type="term" value="P:actin polymerization or depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030239">
        <property type="term" value="P:myofibril assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11280">
        <property type="entry name" value="gelsolin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000031">
        <property type="entry name" value="protein flightless-1 homolog isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF51">
        <property type="entry name" value="PROTEIN FLIGHTLESS-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Gelsolin-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="162" mass="18093" checksum="EE7064B0B3F3067D" modified="2016-11-30" version="1">MHEYMSRLYRVHGKGSSIQLEPVPVDWKFLDPRFVFILDDGLKIYVWMGKKSKSTLRPKARLLAEKVNKEERKNMGEIYVFNEGQEVGDFWVVLGASESGEAPSEPLKYPSSKALSLASAAASDSYGSCGCGRGLVFHFGRPYAGLRYKFLASANLCARLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSE5</accession>
    <name>A0A1D2MSE5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Polyprenal reductase</fullName>
            <ecNumber evidence="2 9">1.3.1.94</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10727</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>a di-trans,poly-cis-dolichal + NADP(+) = a di-trans,poly-cis-polyprenal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:80727"/>
            <dbReference type="Rhea" id="RHEA-COMP:19536"/>
            <dbReference type="Rhea" id="RHEA-COMP:19537"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:231623"/>
            <dbReference type="ChEBI" id="CHEBI:231637"/>
            <dbReference type="EC" id="1.3.1.94"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8 9">
            <dbReference type="Rhea" id="RHEA:80729"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 9">Belongs to the steroid 5-alpha reductase family. Polyprenal reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.94" evidence="2 9"/>
    <dbReference type="EMBL" id="LJIJ01000602">
        <property type="protein sequence ID" value="ODM95953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSE5"/>
    <dbReference type="STRING" id="48709.A0A1D2MSE5"/>
    <dbReference type="OMA" id="HFLFEIC"/>
    <dbReference type="OrthoDB" id="5788137at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160198">
        <property type="term" value="F:polyprenal reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102389">
        <property type="term" value="F:polyprenol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016095">
        <property type="term" value="P:polyprenol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039698">
        <property type="entry name" value="Dfg10/SRD5A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624">
        <property type="entry name" value="DFG10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624:SF0">
        <property type="entry name" value="POLYPRENOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="196"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM95953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="312" mass="36387" checksum="726FD6D22075F2CD" modified="2016-11-30" version="1">MESSVNYIQLIFLTIAILTFLPGLITNYAERFLPSILNQFIRYGRANVAKDGKRSGILKLIEVPKNWFYHSYLFSVFFQSFIIFTVISKYTNYLDISFWLRNTLDVLGGNDRPNTVDAVTTVIAVCLYLFQVGRRLFETLFVCVYSDTKMNVMHYLLAWLHYFGSMFTIVAYSPAFSSRASNFADLTLSFDKLTLIHLVASLLFFYGSWVQYQAHVTFANLRKDKSQKVVSMKHQIPRGGMFELVSCPNYWGEIIIYFAIALLFLFKNYTWNFITIWVVANQLIVGIMNHRWYLATFPDYPTNRKAVIPFIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSN0</accession>
    <name>A0A1D2MSN0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA-binding protein EEED8.10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000619">
        <property type="protein sequence ID" value="ODM95794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSN0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22126">
        <property type="entry name" value="F-box_FBXL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="551" mass="64474" checksum="BDA4BA7F0200B7DD" modified="2016-11-30" version="1">MNLLDIIPEEVIYHHVLPNLNLHELLRFRRVCKRTKSLAENFLNQFEHNVELEINETSKPLKSFLQLGLPASHIYLNNTGPDIFQEIEIAKFLDLYGNSITHLRVHKFFTFLEYHEFLFYQGLTNLHHLEFEEIDATSRNCFNSPDRQKSPFPPNFRNIKSLKIGMVHRSASYDTGYAWDLIEFCNKLESVSHPLYKDVFEGMSIHPDGPFGCVQSMMLQRFYDRPEENNLKYYDLENYEYDVLYPNSIKFLMLCEDCYRFDIRLLNVDAALFRNISPSMRNFFPVVADPVVSLRNVHASVFLMELPNLEKLVISSTLSCSMISQWNKDPKWPKLEILDVTVDSEWLDEMHPFHQGTMDLLEIFFKDVVRLNLTDLRLRFTDFAPGHELPRPKALHVITSCPNLKKLTICKWHGTNKALSKLWSGLTELEEITLESCELLGNVGFVGEDSKDPVFLKLKKLKKLELKNLDEMPKITDTIFRLVLRHMKLTHLILSSECPLDNITAQGIQSLLTGEFASSIEKFPFRDWSLRNMTEEEFHNMEIQFRSYNMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT03</accession>
    <name>A0A1D2MT03_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Runt-related transcription factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10613</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000586">
        <property type="protein sequence ID" value="ODM96062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT03"/>
    <dbReference type="STRING" id="48709.A0A1D2MT03"/>
    <dbReference type="OMA" id="MVLMEST"/>
    <dbReference type="OrthoDB" id="10029800at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001709">
        <property type="term" value="P:cell fate determination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.720:FF:000001">
        <property type="entry name" value="Runt-related transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000040">
        <property type="entry name" value="AML1_Runt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012346">
        <property type="entry name" value="p53/RUNT-type_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013524">
        <property type="entry name" value="Runt_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11950">
        <property type="entry name" value="RUNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11950:SF31">
        <property type="entry name" value="SEGMENTATION PROTEIN RUNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00853">
        <property type="entry name" value="Runt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00967">
        <property type="entry name" value="ONCOGENEAML1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51062">
        <property type="entry name" value="RUNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Runt" evidence="5">
        <location>
            <begin position="17"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="204" mass="22311" checksum="C2EA07BA8A786888" modified="2016-11-30" version="1">MVLMESTSKYVMAERALTEMLTDSPGGELVRTGSPNLVCSVLPVHWRSNKTLPVAFKVIALGEIMDGTLVTVRAGNDENYCGELRNATAIMKNQVAKFNDLRFVGRSGRGKSFTLTISVASSPAQVATYSKAIKVTVDGPREPRSKTRKFLYQTKLATKATPTTTIPFRFRSTSIPGWLHGSTGPSEPQCGFRYDIESDAKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTJ4</accession>
    <name>A0A1D2MTJ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000552">
        <property type="protein sequence ID" value="ODM96326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTJ4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="266" mass="30348" checksum="D5E359B0326DCF10" modified="2016-11-30" version="1" fragment="single">MDASTSFSSSSVPSPRKLSRLNSRQVGIPLVPQPRIDCNIPDLENAASVNVVYEKDNEGDTNSAKYFRISDENNMEICRFMECTRRENVYKRQGIKYLECQDSQGKCIMLVAYPVGLGEVALLSANEELIGECQSNVEFVCLSVKVKYNFYDAANGQRIMKMTAIMPEDENERKFTLMVKRSKNDKMALIKMGLLKSCCHIKFKLNQTSCAERLQIIALWTGFMHNELVEREKLLYLPNVMPKPKKGEKNLLQMIQQTVVNSQTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTJ8</accession>
    <name>A0A1D2MTJ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Histone-lysine N-methyltransferase SUV39H2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_10416</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000558">
        <property type="protein sequence ID" value="ODM96262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTJ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MTJ8"/>
    <dbReference type="OMA" id="LENCEYI"/>
    <dbReference type="OrthoDB" id="1045173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046974">
        <property type="term" value="F:histone H3K9 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10542">
        <property type="entry name" value="SET_SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Chromo" evidence="12">
        <location>
            <begin position="131"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-SET" evidence="14">
        <location>
            <begin position="334"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="13">
        <location>
            <begin position="403"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="15">
        <location>
            <begin position="557"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM96262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="574" mass="65073" checksum="01ACF89DB1B6FCE7" modified="2016-11-30" version="1">MSTLSTASTSDKENELSSLERSSIRCNGKKAKLNYCEDSQSDDEDVEKELDFSGSKGEDEGNSSSDSDLMEPILVKKRKGKRDLSGSNNGDSDYSKDTLPASPAPSDESHETSSPRSRDRSESPETPEGQWEIEEILDFMRDDFGDYYLVKWKDWEAEYNTWEPPTNLLNCEGELLRFYRKKKEEAREALENCEYIELANGKRRKKVRVRDVPPDPRPFDVRVQEFFDVTGNVADEDVVKVFLQWKSKSISAKARWSRNKVNKFLEDGVDGKLSDSDVKALKDELILIEVDNRKRSLSNQIQRMMLMSLDLPSDLNLSTIYVGDGVDIPKDPPVGCNCGKGPTSCYDERATKCCAVQFEYKFAYTKYRKVNVLQGSPIYECNSKCSCGPDCPNRVVQDGKSDHKLSIFRTSDGRGWGVKTLKSIKKGTFVTLYVGEVIKSDEAERRGKDYDEAGCTYLFDLDFNDPEAYPYSVDASKYGNVAHFINHSCNPNLGVYAVWVDCLDPNLPKLAMFALRDIPRNEELTFDYNIQLSGTKSRQEEQEADEKETDQEKPVGKKTICLCGADKCRKFIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTT6</accession>
    <name>A0A1D2MTT6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ascorbate ferrireductase (transmembrane)</fullName>
            <ecNumber evidence="11">7.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_10150</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.3" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000530">
        <property type="protein sequence ID" value="ODM96529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MTT6"/>
    <dbReference type="OrthoDB" id="6372137at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140571">
        <property type="term" value="F:transmembrane ascorbate ferrireductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF24">
        <property type="entry name" value="DOMON RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="787"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="820"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="896"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="944"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1485"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1524"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1554"/>
            <end position="1577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1606"/>
            <end position="1627"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="74"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="746"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM96529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1675" mass="188222" checksum="0CC70700A7C72F10" modified="2016-11-30" version="1">MRLSATATANVSSFGGRCKTHNEYETSNTLAHECEAGPNATKTENFTGYKDYMERRKNCMKINGCPCQCRDGSIFKNMTTWPQNSTCPTLSVVNLGVETNSNVGKYILRSRKAHGMAMLVVTMVFVPFTILVSRYFKETWLSHAQLSNLQIWYLVHIGLTFLTVCLYIFGSVSLRRSKALVGDSLFGETHRGLGWATITFFTLTAFTGPVRPISNASQMTRKCVMFIHALLGIVYYCLGMAAVITSSYIPGSPSSSEVACFTSPSYTEYSSSPTIPLVVTWIVMDFGFHLLLRWADKSLHIQRSMYLPLVSILKYGGHHDMKGFRYRKLMLIIYGICNFGIVLELIIRLANSTKAGCSFGPVTCTFTSGGEKAGNGSFCREFCTCQRPSARIVNSVCIGTGYNDDNYFSIGQKPFRSDYTELFNKRHNKYDNGNIEPSESKTLVLKMYAVETTHGRILSGWLYIRIYVPVGADWIRLLYAQMEDENGNAIGEFVNREICESKKRAVISDLVNRHLSEHYVPCGQVAPAATTASNAFLYVWPDKIHNSAMKQRLIKHYGSSWFSTQTIDINWKFSHTSCDKPKKVRLRAYIYNVDQGNGIFYGTHRGSWININWIGTADILNPGEKGYCNKPPIPDPTLAVPWIKSVDEKINPTEETTNKDIVRSKNFCKPVYIGDDPAIKNVSSFGGRCLKHDEYNTSNTFAHECSAGAMADANFTKYSEYLEKRTSCIQINGCPCQCRVDPIDNTSGLEEPTCPGSKKDLTLQIKMGVKTNGTAGKYIMRSRKAHGIAMLFVTMVLVPYSILVSRYFKETWLKNAKLNLQVWYLVHIVLTFFSICCYLFGSVSLRRSKNVLGESLIVSTHREQGWSTIALFLLATFTGPFRPISSQKTRKCAMIIHALVGIIYYCCGMAAVITSAWIPGSPSGSEEDCFTSPSYTEYSSSPTIPLVVTWIVIDFGFHLLLRWADRRLNIQRSMYLPLVSILKYEGHHDMKFGIQVLQFIIGKFSGIPSGSDFVAKISDLRLFRAMSRGVLAFLLVLGINLSPREFCSSQNPYAELVNSICIGSGLAKETYFSIGQLPFRSLYSGTFENYHSSIASGNTEASEKRTLVVKIYAVKTSTDRFLEGWLYITVNVPSGKGRFRQFYVQMEDENGNAVGEFVNKVMCSSKKKKRDVAQSRKVISAFKDRHLPEYYIPCGQVPNTIVYSWHDKIYNPALYERLNKHYGSSSATTSTSLNWRFSHTSCDKPQKIRLRAYIYTDQSRSGTHRSSWINVNWFGAADVLQEGERGICKGLQIYPPPSTPGSPVRWIKSVDEKIPPTEATTNKDIVRTKKFCKPVYITRSIGAVVEHVPSFGGRCLKHDEYQTSNTLAHQCTAGATIDANFTKYSEYLERRTSCMQINGCPCQCRADKIDNTSGLVEPTCPGFISGRDQKERIMKQIKLGITTTGKVGKGILLRIKIVEIKKITRDSYDFCINGASTLHNSHIQVHVIVTFFTICFYLCGSLALTHNNKMLGHSLKPIAKAHRGMGIATFVLFVLVTLTGPLRRRTVKRKSLMIIHAGLGVLYYFCGMVALITSSWIPGSPSADDTECITSQFFIENSSSRIMPQVITWVIFDCWFHGIFMMMQRWADKHMGIRRKMYFPLLPIFIGREVHDNKVRFAIKVMSTIGSSYMAGSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUI3</accession>
    <name>A0A1D2MUI3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein unzipped</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000536">
        <property type="protein sequence ID" value="ODM96474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUI3"/>
    <dbReference type="OMA" id="GEMSYWA"/>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="582" mass="63834" checksum="C6D9F9F70EB02B31" modified="2016-11-30" version="1" fragment="single">GKMPSTMGCYTLEEVDLSSQVHQRNSHEKGDSFYCSDTTEANSHLHHRNNPNDGRLSRAYNLSSSSTSSVLIALLCLLLVSVVTSPVNATGDPVYIRKANGYLDQLLSSDTLRYFKGTAKEPLKLMRPNLDPAVICRVWHTSLRGVGLVSEDQNVCNISTQEGVQGSDKYQTLSTFASRLVWKLWQRPNPPPIGAVAISFKPAKFLATDLNSTVIGYLDPSMNLGSGIFPSESEPATSCLVLTEIEPERYELSDVQLKRNKGFIEEDIVLAYGRLKYELSSSTSGPINSPLDNGAGDSFQETTKHEPLVQLKPETNEIGTVGMNGGDQVKKGKVESILSYETNILDSWGQGYLMAKGLHSSIKLSDGSTKTVEWGIPSTTAGKTETMTAVAELAPGTGVNVTLRGTRIDGEMSYWATLKTIFKDGSFSTRLLEGHRRVKDIQDIRLEHSRIYFLFNGSVVPDPTTTTTTTTESVPFDLMERNDNEHSHDEDEDNEDEDGLLRENALPVESRSDFQADQGHGFSSSNDFSHQNSNSPAASVAHSDAMRAIYPPSLVSCLLLSVVLVTSLKTFFNFGTRFSMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUI6</accession>
    <name>A0A1D2MUI6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000506">
        <property type="protein sequence ID" value="ODM96750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUI6"/>
    <dbReference type="STRING" id="48709.A0A1D2MUI6"/>
    <dbReference type="OMA" id="FFPIHKD"/>
    <dbReference type="OrthoDB" id="361029at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18086">
        <property type="entry name" value="HsC9orf114-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003750">
        <property type="entry name" value="Put_MeTrfase-C9orf114-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150">
        <property type="entry name" value="CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150:SF13">
        <property type="entry name" value="METHYLTRANSFERASE C9ORF114-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02598">
        <property type="entry name" value="Methyltrn_RNA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="42119" checksum="990CFE026DA255F5" modified="2016-11-30" version="1" fragment="single">LPLKLLTMDSYSDARTTKSKKRNRDDMSKRTMKTNWESKKEKKRHKQQALLEQIDKAKRKPKEKVDGNIIKKVGENSGSSEERSKGLTKPAVQGQGRAYTVSIAVAGSIIDNAQTPSLKAYLAGQVARAAAIFCVDEVIVYDDTDGRGTAGCEQMARILQFVECPQYLRKLLFPIHPDLQFAGLIAPFDAPHHLRRTEALPYREGVVSSKPIKDGSLVNVGLDRDCRVSKKLPQGVRVTVKFDDTAINYILKPKGKLRGTVVSPHLPRREAGLYWGYSQSLLECPFRNGYDVKVGTSEKGSDSRLLKPQSFDHLLIVFGGVEGLEYALENDESLAEDDVRKLFEHYVNTCPSQGSRTIRTEEAILISMNALSQFIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVB1</accession>
    <name>A0A1D2MVB1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 2-alpha kinase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09673</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000479">
        <property type="protein sequence ID" value="ODM96993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVB1"/>
    <dbReference type="STRING" id="48709.A0A1D2MVB1"/>
    <dbReference type="OMA" id="QAECKEM"/>
    <dbReference type="OrthoDB" id="6778822at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009893">
        <property type="term" value="P:positive regulation of metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051246">
        <property type="term" value="P:regulation of protein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000050">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="3">
        <location>
            <begin position="12"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="258"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="432" mass="49144" checksum="8CF17AA38BFF5599" modified="2016-11-30" version="1">MSENDLRSNQHDEVEAMRAMYPGDIEVGESGNPQFTIHLYPQRGSSAGTGVVNLENVTFLKLHVMLPPKYPKVVPLLSIKEGKGLSAQEIQDLDTQLKKLAQQNIGEPMVYQLLNFAEEFLYAHQKKPTGSFHDEMLMRDKLIQERNVQMQMLFKERERLAIKEEILKKQEELRKEEQRRRRELWTNDVSPNGSVEGSPAKGDCFPGSLKQSMMGRRKRRSISSRRRRSNSEGSDSSLSEGSDLVMLEFVSGKTVQQFYKGEVIGRSQRGNTVYAGISNTGSLVAIYEWKFAIPVDRKGKPISTSGDFSTTEGLIKQLQSFEIESNFMQKLEHTNTVLYHGMKILQPADEPGVVYLYMTEEFLRGHTVRSYLQDPQQLCSMALPLLRHITNGVLEALKFLHDNDIAHRFLRDTSIFLDVGGINTNIDDLNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVV9</accession>
    <name>A0A1D2MVV9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sex determination protein fruitless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09631</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000476">
        <property type="protein sequence ID" value="ODM97058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVV9"/>
    <dbReference type="OrthoDB" id="6425912at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016199">
        <property type="term" value="P:axon midline choice point recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008406">
        <property type="term" value="P:gonad development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035167">
        <property type="term" value="P:larval lymph gland hemopoiesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007526">
        <property type="term" value="P:larval somatic muscle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045476">
        <property type="term" value="P:nurse cell apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007464">
        <property type="term" value="P:R3/R4 cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045467">
        <property type="term" value="P:R7 cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF111">
        <property type="entry name" value="LONGITUDINALS LACKING PROTEIN, ISOFORMS F_I_K_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2" id="KW-0221">Differentiation</keyword>
    <keyword evidence="3" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="7">
        <location>
            <begin position="172"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="239" mass="25246" checksum="F582AEB7E95FA03A" modified="2016-11-30" version="1" fragment="single">MRMRSASGGSVGANNNLNSNNNGEVREQRGGAHLPPATCSSAACKSSSGDGLASASSPSSYAAGVQQPPTTPSSSHSHLHISSSSSSAGVRDKRSSSSSFPSVSSSQSGAVVGGAAPNNSGGATNLSQNLQQHPLLPPGVGAPMEVFNLRWDEYHRIVIDSFWSLFTEESLVDCTLVCSPTETVKVHRIVLSANSPYFRSLLASHTAHPHPIIILHDVRYSVLKMLITFMYSSKKTTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVX5</accession>
    <name>A0A1D2MVX5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Histone-lysine N-methyltransferase eggless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09528</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000468">
        <property type="protein sequence ID" value="ODM97156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVX5"/>
    <dbReference type="STRING" id="48709.A0A1D2MVX5"/>
    <dbReference type="OMA" id="IPMLCGW"/>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046974">
        <property type="term" value="F:histone H3K9 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070828">
        <property type="term" value="P:heterochromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10517">
        <property type="entry name" value="SET_SETDB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21181">
        <property type="entry name" value="Tudor_SETDB1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051516">
        <property type="entry name" value="SETDB_methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041292">
        <property type="entry name" value="Tudor_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024:SF1">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18358">
        <property type="entry name" value="Tudor_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00391">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MBD" evidence="13">
        <location>
            <begin position="221"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-SET" evidence="12">
        <location>
            <begin position="348"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="11">
        <location>
            <begin position="426"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="493"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="493"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM97156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="694" mass="79915" checksum="34C367DDA5A82A6D" modified="2016-11-30" version="1">MQYLIFFDDGYAQYVTSDGILLICDNSQPVWNDIYAESHDFIKDYINKYPSWPMVRMSINSMVSTEWNGRWLIARVKEVDCAMAKLRFENDGREEWIYRGSPRLRPIYRCTENKETNNTTRPRHDTAAYKNRNEPTVEYNKHHINTDKKSARKSTGGLNNRNMLGGSSKGQINMEDPDVNIEYQGTMEKIKIPDNVPKPKEYVPHACSPECEIDNKSSQDLKKLSPLMIPLFLGWSREVSRSPRHNIAYRAPCGVSLRDYDELNVYMEKINSPLSVDSFCFDYTVDCLAEFKPTRDLQCIRDISYGKEKKPISCVNSVDYDPLPFMEYTPYRIVGDGVSINTSDDFLACCDCTDNCLDKTKCACWKLTEEGIAFDDRLQDENGIPIIGYQNRRLKEHIISGIYECNSKCRCKSTCLNRVVQNGVSFPLQVFKTSKKGWGIRAMHDMPDGSFICIYSGRVLTDHSANEGGKEYGDEYLAELDFIEINEKVKEDYESDVSDIEANDSMNDEERAENRSQTNDENMESEPEMDSHAGDSSFVANVKVPDQTRSVPIRRTNGQKRNLEVDLLDFHRDEDSITARTVNRFNPQISPRKKKKRPSARTFFGTDESVYIMDAKSTGNLGRYLNHSCMPNVFVQNVFVDTHDIRFPLVAFFTNKYIRAGTELTWDYHYEINSVSGRTLYCFCGTPYCRNRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWA2</accession>
    <name>A0A1D2MWA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dual specificity protein phosphatase 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000460">
        <property type="protein sequence ID" value="ODM97242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWA2"/>
    <dbReference type="STRING" id="48709.A0A1D2MWA2"/>
    <dbReference type="OMA" id="CEGLYLS"/>
    <dbReference type="OrthoDB" id="285418at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14514">
        <property type="entry name" value="DUSP14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052103">
        <property type="entry name" value="Dual_spec_Phospatases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45961">
        <property type="entry name" value="IP21249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45961:SF6">
        <property type="entry name" value="IP21249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="60"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="121"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="182" mass="20019" checksum="3549B43DE61C489B" modified="2016-11-30" version="1" fragment="single">MNRPWLFNKPPGMGPSPKLDGIGAPCSSLMTSSRQTASMMTGGTTPGLSVHGTGLDIMSQINEICEGLYLSSARAIKAQRLRELGITTIINVTIELPTLPWDKIESVKINIEDSPFSNLGQYFDRAADKIEEVRRRGGNTLVHCVAGVSRSASLCIAYLMKYKRMSLRKAYQHVKASEIYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWK8</accession>
    <name>A0A1D2MWK8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RING finger protein 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000442">
        <property type="protein sequence ID" value="ODM97440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWK8"/>
    <dbReference type="STRING" id="48709.A0A1D2MWK8"/>
    <dbReference type="OrthoDB" id="10034606at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20379">
        <property type="entry name" value="Tudor_dTUD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16442">
        <property type="entry name" value="RING FINGER PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16442:SF1">
        <property type="entry name" value="RING FINGER PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="2">
        <location>
            <begin position="32"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="2">
        <location>
            <begin position="322"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="592" mass="68642" checksum="22085CCD660BEEDC" modified="2016-11-30" version="1">MMVIPTRFVTVAGVEMELPKPALLKHIKSYCVRRVVSPFEFYMEEELDQNMIDIDTRELQLMQPFYAKQDLQFIEYDIRVTKWKCYVYQDPLTEVWCRVRVHNFVKKGRSKRALVYFCDYGRQEVVPCESLRRLNGRFKVLGTPLLRCYLYDVLPIRGGFYWPMDAVMYFKEMVNKKFLNAIVMNVSESTVVHNFPDLKLNCGVVLMSKAYKVGETINWTMVKRGYAQSIGIMATSPEMLYLPEKIPHFDGANNYSGAAVLSPNSPIDVPLEELHQITVRAMASNADIYRDSSDMQRPPPPRENPGNYLSKTLRDRLAWIKLSFVEGPSKMFVHMKRKYDELKKMNEELQMEARDLPPPELIPGALVACEIEEEDKEDSEGEKECCKCYCRGVIKSGPSSQSGTTDTTVEVILVDYGCVIRVPVINIHRLPEMFRSMPSFVLRVHLRNVRPKVSSNWHRNTERMLYKYLLSYELAQPLYYACWPESQDKIVLTDIEQPICFNEELNTWVASSVKPPEENECINSMKDDPLLASHFCSYAVNIQYEMLVEEHEFWSFEDISDFLIKRENGVPTKPEVSKNQIHEIITNGFGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWP2</accession>
    <name>A0A1D2MWP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09226</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000440">
        <property type="protein sequence ID" value="ODM97456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWP2"/>
    <dbReference type="STRING" id="48709.A0A1D2MWP2"/>
    <dbReference type="OMA" id="EESTHIC"/>
    <dbReference type="OrthoDB" id="3565419at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="582"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="612"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="688" mass="78572" checksum="EE1E2B2F5AB27EE5" modified="2016-11-30" version="1" fragment="single">VQNAGTTRNKVNQKQINSVNVNIVRDPKLKWFQQQIVTRYLGLSVDLDSKDDTKVAFCSGCASLVTKIYEVYKEFRAVELQLSTKLEELGEIMIEKSKMGESCLSRRSLNGRGNAYIEKVRNVIAQDLMLKRRKLELELDTASLNEDKDCQEGEDLSATKNCDEEEEVVVKSEVEPLGDIDDQPSAMDNIMDEDSSSFNPPAESGQDKPPRSRPSDKNEECNHDDSESEASDSDASYIAAADEVDASESESDSGSDVSCQEDSEDSHRETKTKTMKRRKSPNLSKTEAKRTKTTKPSETETIPEPEKPKFSFNDYIEGPFHCESCDKPYERWQVFWKHLTRVHEEPATEKHINCPFCWTSYAYHQTFSYHLKSKHEETLTKPVFSCDAEFADSNTITTIQLACDQSFMTMEELNTHLLTHSEKIFYCSCKWGFLSPDMLELHKLNHIRSIRGNLKCPKCDIVSAGFAKLTDHFNLRHGAKLLIRKCPICPTSCLSRIALQTHLKNHETGKITPARPHVSSGPQVCELCGMTYKGAKADERLQRHMQKIHSGAEIICDICQQVFTFGIQYDRHLKNAHSISKLTCEVCHKELGSTRRLREHMNIVHSAQPENHLCQHCGNNFKTKRYLQRHIVWMHKELTDVQGKHVCECGEKFHRIELFKRHKKTPCQKTKVENPDGRNDFGVWGAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWP9</accession>
    <name>A0A1D2MWP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000439">
        <property type="protein sequence ID" value="ODM97480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWP9"/>
    <dbReference type="STRING" id="48709.A0A1D2MWP9"/>
    <dbReference type="OMA" id="STRYICK"/>
    <dbReference type="OrthoDB" id="204305at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM97480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="362" mass="41958" checksum="087ABCDA8B8E72E4" modified="2016-11-30" version="1">MRLANSQNFRFAVISNLNLQFGSISTSTSIPISTINDVRSTTLDPSQIDIDVSLSTSCECFKYELYRRYLDTQQERHAQSYCSKEANLYGPYTRVISFTLFQSNSTEELAWEKGEAKHWERALNENLERMRKYFPGWIMRVYSNLGENEFVCKLRCNNVDFFWCDIKNIPKYGDLSMVMEARSWSFLPLGDPTVDVFLARNLDSVLLARDAAAVQDWLKNTTKPFHAFRDHPFHADRVLGGLWGGRNNLLRRNNETELFRLHKMVVNQTYLTLQEKSKVADQTGFTSFFLPLLAEENLVVCYDAFYCDLWRNVTLTRPFPTERNGTEFLGDVVLWGESGFGEQLTECPLSCRPEYGKSWKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX70</accession>
    <name>A0A1D2MX70_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000425">
        <property type="protein sequence ID" value="ODM97647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX70"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM97647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="106" mass="11577" checksum="D02EE5D3E7A138FB" modified="2016-11-30" version="1">MVYLQVKSGLEECLSLGAVGTSSSLDAQSASYRWLYNQLLPTETVYLEIEDEGEETISLNEVTIYSINGGGPVCTFAYREINIIPVSGSIYQIQNIKGEECLTSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY73</accession>
    <name>A0A1D2MY73_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450 4d2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_09093</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000428">
        <property type="protein sequence ID" value="ODM97595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY73"/>
    <dbReference type="STRING" id="48709.A0A1D2MY73"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM97595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="283" mass="33246" checksum="16541250E69BA5CA" modified="2016-11-30" version="1">MHVVDFTLQTLFLKRKSKYGGERDSDKYKGFHSLPGPRPFPIRFIGNALQLPKRRDMHRMMDEMYAKYGQCYRLTLLNEEIVCLNTAPLAQAILGSNDLNHFRKGEQYDIYFSGTEGLPMLTGEKWKTRRKMISGSFKYKAFQRYNPSFNKHTEKLLEQLDKLYQDGKAHLINDLVKDCVFKQSSEAIMGIDISGNEGGAVFAKSLETYAQTVFKMYCCQYLNIIAERLCKPWLLLNWVWRFHPLSFKQKRVFDKMINVTKTVKINSKIHLFRNKTDNFQLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYP9</accession>
    <name>A0A1D2MYP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-loop-helix protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000375">
        <property type="protein sequence ID" value="ODM98177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYP9"/>
    <dbReference type="STRING" id="48709.A0A1D2MYP9"/>
    <dbReference type="OrthoDB" id="6125763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050283">
        <property type="entry name" value="E-box_TF_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349:SF97">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="224"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="344" mass="38533" checksum="6C99A3D60CEEAFDE" modified="2016-11-30" version="1" fragment="single">MDSSYNCDHFRLSPDTVTSNSGPSPHSHSHSHPSVSSATTCSLHKAGGSLDIHSEYDLSLTHHHHHLPHIQSNSNHQNSLTHRSNLGSNTPEEFCESVHAISDYSCEQNERSQNIMHHQYASQQQQMSTQVGMTPVEMEDLEQDDLPACAFANMNQGPTRMELAGGNVASTSGQGGNHHFGVTDESGRIEGPENYYPPGGPYKMQRHSANIRERKRMLRSVPRSEPRIPIFLERHYGESINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYIALLREVLVSKYDPLTYVEKCLKGEIKCDQAAAWNTSDLTARLSWINWENLGVSPNRRSSLTSLTLSSDSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZL3</accession>
    <name>A0A1D2MZL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000355">
        <property type="protein sequence ID" value="ODM98430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZL3"/>
    <dbReference type="STRING" id="48709.A0A1D2MZL3"/>
    <dbReference type="OMA" id="YKARRLM"/>
    <dbReference type="OrthoDB" id="10056177at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="24"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="623" mass="69038" checksum="A11F6C595DEC80FD" modified="2016-11-30" version="1">MEVTYCILLMFKIGERSSFAKLSFIFSAMAAILPYLTIQMKDIGISLSEIAIIYAVLPFTAFLGPPIMGIMADQLGQYKGVLIVATIINGLFHTLLLAVPKYSETPIYAPAVIEFRGVSGAILRPESLALCDNFDISVLSASNRLRNQMINVYSCNAANDSNVIASRTPWNLPSLCHVTNNELLEQDENVNPIFTCGNANAFHRTKRSLFENSGKNKCALKVRINSEAPNLETFTCKTNYTFESGDKLVEGNNSLTFWLYFAIRIVGNVFMNACFSLLDATTLAVVGNNEGSEYGKERILCTIGAAVVSPLAGLLVDRVSAAKGYTDYSSAFYFSNALLVINIIGYFFMKLTVEKPEEGFWKNATDLLNYPEVVVFLGMIFVLGNLWGFVESYLFIFLDELNAPKYLLGLTLTVGSLAGIPFLYGAEKLVTKAGRVNIIAFAFIVYFIRFFGYSYIPNPFWCFPFEAMEAFTYHLMWVAAATYCAVLAPKGLLATLTGVMGSLHYGLGKGSGAFIGGYLISVTNTRLSFRYFGIAAGIFGTIYLLINKFWLEGAIKRRNERGILYCYTKTRMYTKKLIIESVFDLPMILIENDINGDDENPARTIPSILQEQKQAMLPSNNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N017</accession>
    <name>A0A1D2N017_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_08061</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000339">
        <property type="protein sequence ID" value="ODM98619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N017"/>
    <dbReference type="STRING" id="48709.A0A1D2N017"/>
    <dbReference type="OMA" id="ANQERIY"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01364">
        <property type="entry name" value="KISc_BimC_Eg5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000051">
        <property type="entry name" value="Kinesin-like protein bimC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047241">
        <property type="entry name" value="KIF11-like_kin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF12">
        <property type="entry name" value="KINESIN FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9 13 14" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="15">
        <location>
            <begin position="19"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="98"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM98619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="441" mass="49235" checksum="6CF68642077C4CFD" modified="2016-11-30" version="1" fragment="single">MDSKPEGVSSVGKRERNQNIQVYVRVRPQTGGVPSVIDTPGTKEVVVRERTVANITKTFTFDRVFDWNSTQQEVYRTVVAPLLKEVLLGYNCTVFAYGQTGTGKTYTMEGELQDKKGSSVSLSVPQPPICESVHAGILPRALSQLFDEVRKMDCEFQVRASFLELYNEELCDLLATADPNQSKKILRIFEDSSRKGSVVIHGLEEVIVQNKQEVYDVLTRGSQMRKTASTNMNHSSSRSHTVFTITVHMKESSVDGEEMVKVGKLHLVDLAGSENIGKSGAVDKRAREAGSINQSLLTLGRVISALVERTPHIPYRESKLTRLLQDSLGGKTKTSIIATVSPAGSNIEETLSTLDYAHRAKNIMNKPEVNQRLTKREALNIYTEEIERLRKDLMAARDGAGFFIDMTNYNNMQSQITCMNLELVEKTNHVQSLKDSIEEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0P7</accession>
    <name>A0A1D2N0P7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000350">
        <property type="protein sequence ID" value="ODM98485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0P7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10840" checksum="90357E26D5BBD2C6" modified="2016-11-30" version="1">MYMLHRTLFLFQSGNRLEKKSSSSSCIFYNQMEDGKSRRSKSAKKSKSHKRFDVTRSMEEVRGDIVKGKPCAPLSAFYLRTLEEQIAEIAWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N125</accession>
    <name>A0A1D2N125_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter G family member 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08054</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000339">
        <property type="protein sequence ID" value="ODM98615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N125"/>
    <dbReference type="STRING" id="48709.A0A1D2N125"/>
    <dbReference type="OMA" id="IRICHKT"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03230">
        <property type="entry name" value="ABC_DR_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038:SF3">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 20 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="609"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="30"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="636" mass="70507" checksum="09887BF2894F4AD0" modified="2016-11-30" version="1">MSFNEFELPQTSRGIGGNPRIRMEDRRDAVLIKNASKKYGKDSTACTVLSDLNMCVKEGTIYTLLGSSGCGKTTLLSCIVGTTQLDDGECKIFGLKPGTKECGIPGKNVGFMPQEIALYGEFTIEEAMHFFGTVNGMSNDKIKNRMVFLKKFLNLPSSERQVRNLSGGQQRRVSFAVALLHQPKILILDEPTVGVDPMLRKSIWRHLTDLVESGKTTVIITTHYIEEATGAHRQDRPVDEDGIENSSEARGTVKDDAERLETADSGLSLNTIPDSERIGVAFCNERNIVKPNNINDHAGGETPKDKNFNTGTGIPKPDHCPPFPAVVPKYHENLDNVEITERTLKHEAIRLLHFLLAGGTSCAFLHCHWGQPTDLPLGVVNLEVANSAECMTSTGCSISNMSCNFLKLIDNKTLTLNYFDGERMALEAVKKGNVWGYLVIPANFSAAVLQAGVDMVKQKEDSFLGTHVKLALDMTSKFKENFAVEHNVFEMDKLNHLFHRSANRLYNSTHFPCHLSSLIRICHKTADSIIQLIYLNLCIDAYYIYTMFQIAEPIYGSINSNFREFMAPGIILSIIFFMSVALTGSAFITERKEGMLNRMLVSGVSTGEIITAHMLTQYIIMAGQTVLVLAVMIVWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1T1</accession>
    <name>A0A1D2N1T1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PI-actitoxin-Aeq3a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000316">
        <property type="protein sequence ID" value="ODM98855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1T1"/>
    <dbReference type="STRING" id="48709.A0A1D2N1T1"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF374">
        <property type="entry name" value="BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="4">
        <location>
            <begin position="31"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM98855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="22591" checksum="EAA9640F263F0958" modified="2016-11-30" version="1">MFSSIVKVQDPCNGEFGISCQINMDEAKQICSLPVDVGSCRSNYTQYFYSMEKSMCVPFEWSGCKGNRNRFETEAECITYVRFSFRSRGSLRNSFYDFVLPGNLQLPAETETRRNSIFNQANPSKNEEVTTELPESQIATKMWVPARPRRLWRARRAEDRGIPMRAVRKALATEAGSIFIPLNNHIIPQQPSVGFGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N368</accession>
    <name>A0A1D2N368_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000259">
        <property type="protein sequence ID" value="ODM99723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N368"/>
    <dbReference type="STRING" id="48709.A0A1D2N368"/>
    <dbReference type="OMA" id="CIAHHAV"/>
    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="6">
        <location>
            <begin position="78"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="6">
        <location>
            <begin position="163"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="29245" checksum="55135697FE4ACA80" modified="2016-11-30" version="1">MTLRPSVPQSIRYSSVHKRAKQRIYDERFYDRARRQSSDVPELCIAHHAVDADQLKGESAQACRTKMRQIVVNQLVKVPEDVTVTAKSRRVIVRGPRGVLRKAFRHMAIDIQVLSKDTVKVEKWFGTKKEIAAVRTVCSHIENMIKGVTKGFQYKMRSVYAHFPINCVTTDKNSMVEVRNFLGEKYIRKVKMSKGVTVTNSSKQKDELIIEGNSIEAVSRSAALVQQSTTVKRKDIRKFLDGLYVSEKTTVEVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N467</accession>
    <name>A0A1D2N467_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="6">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Carbon catabolite repressor protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Cytoplasmic deadenylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Glucose-repressible alcohol dehydrogenase transcriptional effector</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">Ocin01_06613</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CCR4/nocturin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N467"/>
    <dbReference type="STRING" id="48709.A0A1D2N467"/>
    <dbReference type="OMA" id="PHYYARA"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09097">
        <property type="entry name" value="Deadenylase_CCR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000002">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 6 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="17" id="KW-0804">Transcription</keyword>
    <keyword evidence="16" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="24">
        <location>
            <begin position="72"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="23">
        <location>
            <begin position="215"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="560"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="564"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00030493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00031469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00033317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ODN00063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="595" mass="65879" checksum="33B95DCF65FEE4F0" modified="2016-11-30" version="1">MTIKDSGNTASGGSATPSPNNIGQGLGQNAGASSSNPKRTHTIMSAEDAAAGKRSFWAEMELTGNIRNISPQLFDLTHLTHLYVNDNSLTKVPPEIGKLVNLQVLDASNNKLRSLPAEVGDLIRLRELLLANNYLRTLPFEMGRLFNLQLLGIKGNPLPQEFSSLHAEVNGTSKLLTFLLDSLPVPTVEPPPRAWLPLATPTRSKPACIFTVLCYNVLCDKYATRQMYGYCPTWALDWMYRRKAILQELRHYSADIISLQEVETDQFYNFFLPELQQDGYAGIFAAKSRAKTMSESDRKFVDGCAIFYRTAKFNLIKEHLVEFNQLAMANAEGSDDMLNRVMTKDNIGLAALLETRMEAWDNGVPHGYSPPLLVCTAHIHWDPEFCDVKLVQTMMLMHELRLIADESSTGRPNASSAGKSPTDKVHLLLCGDFNSLPESGVIEFLQTSRISAKHPDFKDLGYKSCLQRISYNSDRTTEYTHAFRLSTAYSAEVMPFTNYTFDFKGIIDYIFYQKPNMTPLGLLGPLDPQWLVENKVVGAPHPSIPSDHFPLLVELEMTAGSGSGSSSSGNQQSSSTQLSTTSVSTTSSSSTSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4B9</accession>
    <name>A0A1D2N4B9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphatidylinositol 3-kinase regulatory subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06911</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000256">
        <property type="protein sequence ID" value="ODM99775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4B9"/>
    <dbReference type="STRING" id="48709.A0A1D2N4B9"/>
    <dbReference type="OMA" id="SERCPQN"/>
    <dbReference type="OrthoDB" id="3175255at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20830">
        <property type="entry name" value="C1_PIK3R-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000080">
        <property type="entry name" value="Pi3K21B, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032498">
        <property type="entry name" value="PI3K_P85_iSH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818:SF3">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16454">
        <property type="entry name" value="PI3K_P85_iSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00678">
        <property type="entry name" value="PI3KINASEP85"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="5">
        <location>
            <begin position="45"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="6">
        <location>
            <begin position="116"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="4">
        <location>
            <begin position="378"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="4">
        <location>
            <begin position="644"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="835" mass="95041" checksum="C0CE6637747F1B82" modified="2016-11-30" version="1">MDEAVGIHDEFQQQAVLSSVEELRAHEQNGGDTVFKNVGSHSPKSHEFVRMTFATLTRCDSCQKFLRGLFHQGVICQRCGYIAHQKCIALGLPSCEPASDDFRPQLGYLRHRVSGKHLCLTFDPSTAVAPDVLMALCGEVERRLDFESTRLVPELASIFDGNIATLAQTKPELWDQLATCLASNVNPAAALANVVKDWRLQEVASAIRRYFRELPEPLIPTNLYEDFIHVGKLQIDSDALLMMDKLIVNSLPQHHSRCVQYFGSHLAKICKISEKWGNNGHAHVDAEKILSHFYGMVILRPTWENIISILDNFKTHVRIVSLLIELYGGMGKEKRSRRKANLISEMDRASVEYVISRQESLSSDKFNKTERELQDAEWYWEGLTREEVVEKLWDCPDGSFLVRDASTKNGEYTLTVLYGQTPKLLRISQRSGKFGLTEPYNFRSVVHLIEYYREHSLAEYNNSLDVKLHYPISKFDKGDEEEDKDKLLAVLGEVSRDYLVKSRYFELHSTLHAQTADDIHLKKQAVDAFDGAIGFFRQQITVHKQLQAKASGDVKTMKELDDNFSYLREKLKNMEVSREQVVQSLSKQTAYCRLVETEIISIKPQLAHLRKQRSRLVKRMEIMNVDVESALSPGIIDVWDDNLWYKCDASRQEAQYILKDRPEGTFLVRKSSKGELALSLTLSGGVVGHCIIYQGSVGFGFTRQTTYFPSARALILYYSCHSLEECNQQLRTCLKYPAFALTSHGVGSSNNGLRVVGVLFLALGLCQLASSQRYRQRNPWPWSRYTTTQRSIEEIRNPIVVTTSAPPPPVNFFPIISPIEQRQIMDNADVQLLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4P6</accession>
    <name>A0A1D2N4P6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Complex I-SGDH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase SGDH subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_06438</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Complex I is composed of 45 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000221">
        <property type="protein sequence ID" value="ODN00233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4P6"/>
    <dbReference type="STRING" id="48709.A0A1D2N4P6"/>
    <dbReference type="OMA" id="HHHMTIK"/>
    <dbReference type="OrthoDB" id="9995605at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019173">
        <property type="entry name" value="NADH_UbQ_OxRdtase_B5_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13178:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13178">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09781">
        <property type="entry name" value="NDUF_B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="18" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN00233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="191" mass="22755" checksum="CF91752BC3AFCF3D" modified="2016-11-30" version="1">MTVMSLISASRPTYILNNLVRRDNSQLQQIIRTLRTSGTKFGGGHDRTLQILPSRYQWHKFKDLFHFYFFLGVIPLTAVVVYANIFIGPATLCEIPEGYEPEDHEYFRHPITRYLVKNYITTMQESYERNMHYLVHMEQKRRMRLLATRVEALMRERGDYPNYYTTRTIHGKYARAMQIERDYIQSTTGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N547</accession>
    <name>A0A1D2N547_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Orexin receptor type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_06497</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000227">
        <property type="protein sequence ID" value="ODN00185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N547"/>
    <dbReference type="STRING" id="48709.A0A1D2N547"/>
    <dbReference type="OrthoDB" id="10036964at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243:SF233">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="105"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN00185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="27026" checksum="C6EB3C9BB239722B" modified="2016-11-30" version="1">MDLDENSSEKIMTLGKSEASSSISSPSVRLPSEGTFASNENYDLTDDKVEKDLLVPTMNSTSWLLYTNMTDMDMSDYGVAEEFPYYIRITSTLLCGFILLIGIIGNILVPVVVWRNKDLRSSTNIFLINLSLADLLILLVCMPPVLIELHSKPEVWVLGAAMCKSIYFFNTFRLKIIFYIKEYPCVKCMFIDRTTKERLFEEIIKCIFLFSNCTLESPNLPVQAADTLQLFIEASDLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5D1</accession>
    <name>A0A1D2N5D1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Unconventional myosin-XVIIIa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000219">
        <property type="protein sequence ID" value="ODN00275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5D1"/>
    <dbReference type="STRING" id="48709.A0A1D2N5D1"/>
    <dbReference type="OMA" id="RFHQNTV"/>
    <dbReference type="OrthoDB" id="445896at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="234"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="341" mass="37261" checksum="080E18DC03C36F21" modified="2016-11-30" version="1">MFQFMRKSDRDRDRDKKAGKVDGKMEKVGFGKKVKDKLSPEDLHRLDEIRRSFKLGKGKKEKQKLPSGIIADYSENFMQPPTTPSSLQRSPGSKEQDGMPSITHSDSSESSLSITSMTNVDGGSSSAKSTMSRGGPAKPPRASTKSPPPVPPRQSSSSRYSGDYGSADLSHPGRSPSRPPTSASSSSFTPSYVTPPQSPSHNALSHAKFYPEPELDFSDQLLPSIASKAGCCRTIIVERQPSGDFGFSIRRSSVTVKSGAQDSILYVEPTQGSVTRDYSQHFLLPGDRLIAVNSVSVESKTRDDVINLIKSSQQSITLKVLSNMHWMENISDIEYEPVSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5N6</accession>
    <name>A0A1D2N5N6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_06117</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000199">
        <property type="protein sequence ID" value="ODN00564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5N6"/>
    <dbReference type="STRING" id="48709.A0A1D2N5N6"/>
    <dbReference type="OMA" id="NKSYPCE"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000404">
        <property type="entry name" value="POZ-, AT hook-, and zinc finger-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000395">
        <property type="entry name" value="zinc finger protein 513"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408:SF64">
        <property type="entry name" value="LINKING IMMUNITY AND METABOLISM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="490"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="524"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="552"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="580"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="22"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="356"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="601"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="425"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="631"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="656"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN00564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="676" mass="73457" checksum="F2BB954C4DD1134F" modified="2016-11-30" version="1">MDIVDDDSALIHSKFHKAKRGLLSSSSSFQSQSQNHQSISPQHQSPSPSIADAAPSSEQNCYLQTPFPPPNSSATTPIAASTIVDSIVDTEFRVSEPLQKAALPQQQQHNYNIIHAKLEAVAAAAQQHNHHHHHQYSGGTTILLSPPFGTNSVAGIPAAGSSAGSPNHPISAGLNFGGPPPPPPLPTIHPPLPMPGTTNFHAREQVFRFDSTDRERYLCSAISEEDEEVFSPGPSPSSFSTRSYDSPHIVLDSPRITISPLRIEDSPPTIQNLTPSPIMDSHNRLFPRVHPGLAVLPPTTNIDQARCLFGVPSSPVSPLTPNTPLSPSPLSPHEHMFQQGILEELYRRRCHSDSDLPCLPDSPKLEPTDLSVKSNSRATQRTKRWIPHPLVMPAIKSGSLESDQSTPQDSPLDLSMKGSRERFGSTPNCDNFGTSRTISSLVIPPHTTHGGSPLSPAVISPTTRHSVALRYNLEVSPVVEESRPGGDMGFVCPVCGQVFSLHDRLAKHMASRHKSKPHDPNKSYPCEVCHRSFARSDMLTRHVRLHTGVKPYTCKMCGQVFSRSDHLSTHQRTHTGEKPYKCPQCPYSACRRDMITRHLRTHTRNSSSSSSDLMGSVTTPTSTSSSSEPIVDDRIIKTEFSRPPSSSSSFAPESPTQLSPALNLGSLSVHSPPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5R1</accession>
    <name>A0A1D2N5R1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ferric-chelate reductase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000196">
        <property type="protein sequence ID" value="ODN00620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5R1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905081" description="Ferric-chelate reductase 1" evidence="3">
        <location>
            <begin position="25"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="569"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="624"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="74829" checksum="33AA5451D4D2B677" modified="2016-11-30" version="1">MLIFYLRGILLLLYISEWLLLATSQPRANYHIGYRKVNWCVTGRDEPELHEFPYSQFVPLLRRTNRLKLDSHIRYDLRFFDITTTQNDVGLGGRLFKTTHVVFKAEQLKDPEKTTKQVWEPMEIEGLVIQANSNPYTLALPTGQFFRPGADKDHIGEKDGELDVEIHCEDCDNLYWAGTIMCRKRAITQVEHPNILAWHYKQLRANETRPIHSSPSSGDDDIPSDPGEIPSPGPQSEVHSNFRFYSPKCAPTRRLMFTILVVRSFARQEYDIFYRGPYEVTVRDQENQSDLHPSPYFYLYTQVATCHHHSSSDITLEHPKKFEDFEMNHFFDCCIREEENRKTKITVELFGWQRRKSVSCLEKLYRKHTGPFDPRTIESGEESFQCFYPHMPRNCEDKDFESAKEHYDRCPPCEMPPTTTTMQPTTKPPSIYKRTVHGGLMIMTNFCLQPIVIYIARFYKETFNTKSYKGSKSWYWMHLLGGMVSSGMIYFGYFSGGHRNPDEVRGHVAIGNVYIITLAFCYLTAWGRHKDTFVTTIAELIHSCFGYVTISLAIASVESAPGLGFTSKMLVYLMVATQLFFMIILSMHICLLDKKLGMKPKRRHFPTVEARFDEIAVPKAKFRIIMLVIFSSITFCLSFASTFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5R3</accession>
    <name>A0A1D2N5R3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Retinal homeobox protein Rx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_06075</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the paired homeobox family. Unc-4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000197">
        <property type="protein sequence ID" value="ODN00597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5R3"/>
    <dbReference type="STRING" id="48709.A0A1D2N5R3"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990837">
        <property type="term" value="F:sequence-specific double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46799">
        <property type="entry name" value="HOMEOBOX PROTEIN UNC-4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46799:SF1">
        <property type="entry name" value="HOMEOBOX PROTEIN UNC-4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0221">Differentiation</keyword>
    <keyword evidence="8 9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 9 12" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Homeobox" evidence="11">
        <location>
            <begin position="385"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="8">
        <location>
            <begin position="387"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="163"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="251"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="354"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN00597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="427" mass="47235" checksum="56A05BA053961EFD" modified="2016-11-30" version="1">MMMSQSGGSSGSDLGGGTSSPSQLIFHHPHHHRLNFEHGGSSLINYPAATTYSNLISGSENNKDIRSSVSSSGATVSSSPSISRSQSISPEILTGKAVSPSSAASAKCQSVYSSIEKLLASSFAPVSSCKSNVSADEVMVESRAAELCASTNMGNNTSVMVVEEPTADSERRSQKSEDPRHQKGSSERVTSQIPKSKRVRQEDLSGSEEEKEDQSLSSNKKRKRAPHQSNSNSKLTCVKIEKEVGMLYKNGEAETQAQDDSGLIVNGNESFSHEEEEKEEIEKNGGKSSSSSEDNNIKYPIMMLSNKSGLAQDDEEDEDEDVEVNDEDDDNTHQYHRQQPQQQHDYSSQEEEQSDHAEQQPYHDLESQNHRHSSLHLDESGQPSRKLRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLALVQRCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N608</accession>
    <name>A0A1D2N608_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000194">
        <property type="protein sequence ID" value="ODN00661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N608"/>
    <dbReference type="OrthoDB" id="10598520at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="13247" checksum="6C6B5B2EEDD1630C" modified="2016-11-30" version="1">METEKDTCMRPKWMTKLLGCSHKGGIHSHQLPALLTELNPGLNIDEVVLKVLIKENDRNGSGVLDFDTVTKILFQLILKQPCNESSELDSSCSESDEECSCSSPGACSMKITDFIIFPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6V0</accession>
    <name>A0A1D2N6V0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium-independent sulfate anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05692</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000177">
        <property type="protein sequence ID" value="ODN00993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6V0"/>
    <dbReference type="STRING" id="48709.A0A1D2N6V0"/>
    <dbReference type="OMA" id="ITICITQ"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="367"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="487"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="56561" checksum="1FE1447ED1FAECAD" modified="2016-11-30" version="1">MTPIIFSNFDGTRTATTRFVLHSSYNIITRSIYIIRIPSCYLLLGFIVNFISAPVNSAFTSAAAITICITQIKGLFGLKFPAEGFLPTIKGAIAHIMEVKLWDSILSLICIIVLLFLMKLQLILSFLIKRVPILNKPIWFISTARNAIIVIVCTAIASAIGETQPFTIVGRIVPGLPDFTIPPFTILDPATNVTHTFSDILEEGSSAIIVMPLLAIMEHITIAKAFAGENTIDASQEMLSIGVSNIIGAFFSSMPVTGSFSRTTVNAMSGSKSPMGGLITGTIVILALRFLTPYLYVHSKSLAAPPKCAPEMDFIPWSLTFLVSLFVGLEFGMLTGFIISVIYLLYYAARPGVKVKKGYSTSGKEFLLVEMDRSLTFPSVEYIRYAISKASQVWGQNKLPVVINCLHIQFADYTAAVGIKEVIDLFKKRDQQIILWQVKPSIVRVLSAVLNVPGKEEYCHFCRSEEEVESILDAKCSTEKQLETLKPMDQDSGVEVHTPHPTHREKYSSIPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7P1</accession>
    <name>A0A1D2N7P1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000161">
        <property type="protein sequence ID" value="ODN01293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7P1"/>
    <dbReference type="STRING" id="48709.A0A1D2N7P1"/>
    <dbReference type="OMA" id="EWIPFHP"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811365" description="Carboxylic ester hydrolase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="151"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN01293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="689" mass="77855" checksum="8DBDAA11A08E748D" modified="2016-11-30" version="1">MLVTTYLVNLLCAVVECRGTMPLPEAYIAEYASPSFAQQRSIDPLNFTENIFLSHNSVNNDQSSRRKRLFSVLENNITNEPPQNGIRSFSSRLHSTMSDLVNVIPNFVHSVSRVMQNGNAREGSALGFRFGRSGADNNTVGVNAYGDRHPVVILKHGGGVEGYFMGTMNGRKLAAYEGIPYAEPPVKNRRFKAPEPKRPWKGIMKTQKPGNTCLQTHPLYFFRVTGDENCLFLNLYTPKIPYRDDNKTYPVLLWIHGGSFMYGSGSEYGPSYLLDQDIILVTANWRLGALGFLSTGDNVASGNWGLKDQALVLQWINKEIFSFGGDKNRVTIAGQSAGGVSAHLHLIANKVTDTFHHGMSLSGSGFGFWPVLSKERAGRLTKTLAKRLNCPYRSSTELIRCLKGISGSWIIMTQFQLFEWIPFHPLVLFAPTVEPEGADSYLTKWPADAYANLEVQKKPWIFGQTSKEGHFETYQLKLFMQAPNMAMNIKKYLPMILDYDYYTTEPVTSAVTQKLMQYYDGNPDKNGLGMDTISDMYTDRYFSNTLQKAIRAHSRIAPTKTYAYIFDYTGKYNLGQLFGVPRSEWASAHTEDVMMIFNSSSFHHGLSKRDVEYQLSEIMTNVVSNFAATGEPNYRGGNNNMVKLWGNAIDPMDSQRTRIQYLRFGNKVEMFQDPFRNRVKFWERLGIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7P3</accession>
    <name>A0A1D2N7P3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Actin-related protein 2-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05399</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000162">
        <property type="protein sequence ID" value="ODN01290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7P3"/>
    <dbReference type="STRING" id="48709.A0A1D2N7P3"/>
    <dbReference type="OMA" id="WEDMQHL"/>
    <dbReference type="OrthoDB" id="10251209at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000538">
        <property type="entry name" value="Actin-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000005">
        <property type="entry name" value="Actin-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="394" mass="44648" checksum="AE7C401FC0C81D02" modified="2016-11-30" version="1">MDSQGRKVIVCDNGTGFVKCGYAGSNFPEHIFPSMVGRPIIRAANKIGDIEVKDLMIGDDASKLRSMLEVNYPMENGVVRNWEDMLHLWDFTFGPAKMDLNPRECKIMLTEPPMNPTKNREKMIEVMFEKYQFAGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYDGFALAHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYIGYNLETEQKLALETTVLVETYTLPDGRVIKVGGERFEAPEALFQPHLINVEGQGIAELVFSTIQQADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLERVLKGDTEKFSKFKIKIEDPPRRKDMVFIGGAVLASVMKDKDTFWMSREEYEERGVRVLDKLGVRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7V1</accession>
    <name>A0A1D2N7V1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Cytidine deaminase</fullName>
            <ecNumber evidence="4 12">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 12">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_05336</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 12"/>
    <dbReference type="EMBL" id="LJIJ01000158">
        <property type="protein sequence ID" value="ODN01339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7V1"/>
    <dbReference type="STRING" id="48709.A0A1D2N7V1"/>
    <dbReference type="OMA" id="RFITPCG"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000008">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="13">
        <location>
            <begin position="11"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN01339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="147" mass="16344" checksum="FBEDB3EB878CC7F9" modified="2016-11-30" version="1">MEIKDLSDLDDVVQTLIQKSVEAREKAYCPYSNFAVGSALYCDDGTIVTGCNVECIVLGLTNCAERTAVFKAVSEGKTKFTMVAVSAVNKDKIVSPCGQCRQMLAEFNPRIPIYLYNPDTKMVGCQTLEYFLPHSFNPENVRLNENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8E8</accession>
    <name>A0A1D2N8E8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Roundabout 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000148">
        <property type="protein sequence ID" value="ODN01533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8E8"/>
    <dbReference type="STRING" id="48709.A0A1D2N8E8"/>
    <dbReference type="OMA" id="IEHPENQ"/>
    <dbReference type="OrthoDB" id="428111at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10341" checksum="FE0E2BABE40EBF31" modified="2016-11-30" version="1">MEIRDAGQPPRIREHPADSVVPKHEPVTLNCKADGDPTPSIKWLKDGRSLQADQRHPSKLLLPSGSLFFLREEEGTRWEQKLGWMSLVSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9E6</accession>
    <name>A0A1D2N9E6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9E6"/>
    <dbReference type="STRING" id="48709.A0A1D2N9E6"/>
    <dbReference type="OMA" id="WDVCFAD"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="2">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10817" checksum="42333478CA95E754" modified="2016-11-30" version="1">MSLEDIQKDPHLQNFIEMETQKQRYQHLVHGLTERCWDLCVDKPSQKLDGKQQSCLVNCVQRFIDTTNFVVNRLEKSQGLLTAATSADSEFMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAF3</accession>
    <name>A0A1D2NAF3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 9">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04469</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:19890"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 9"/>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAF3"/>
    <dbReference type="STRING" id="48709.A0A1D2NAF3"/>
    <dbReference type="OMA" id="KEYCFLS"/>
    <dbReference type="OrthoDB" id="932129at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-alpha-D-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000001">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000002">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 12" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="57806" checksum="B9973BA9BC6821C9" modified="2016-11-30" version="1">MEWLGFGAKAMTNEKRAGSPHEAAEFAAMTKRDAQIRMDHELKELIKSSIPEEKEGIEKEFDGFMNIFNKFLQASATAVDWNKIEPPAPDAIRLYKSLPTPETSEIRNMLSKLVVVKLNGGLGTSMGCRGPKSVITVRNDLTFLDMTVQQIEHLNKTYDADVPLVLMNSFNTDEDTEKIIRKYTGFNVKIFTFNQSRYPRIDRDSLTPIAKTCNTADNIDAWYPPGHGDYYLSFYNSGLLKRFVDEGREYCFISNVDNLGATVDLNILNMLLHPSPGHQKAEFVMEVTDKTKADVKGGTLIQSENHLRLLEIAQVPKDHVEDFKSVKKFKIFNTNNLWINLPAIKKVVDEKTLDMEIIVNPKHLDNGQNVIQLETAVGAAMKCFNGCLGINVPRSRFLPVKKTSDLLLVMSNLYSLKNGTLEMSPLRMFPTTPLVKLGDNHFSKVKDYLKRFQTIPDLLELDHLTVSGDVTFGRAVSLKGTVIIIANEGNTINIPDRAVLENKIVSGNLRILDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAJ4</accession>
    <name>A0A1D2NAJ4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000118">
        <property type="protein sequence ID" value="ODN02273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAJ4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="45941" checksum="C52D2B8034046026" modified="2016-11-30" version="1">MAANGEVEKKTGSDITSAAPDAKSESHPIRDGTIACACECNKKVKDLEAAMNLISVWKVEVDKWMLSNFGFAVSISSPGGPDEILREVDNPHDNCTNSNNSNVDPLGNDAENGPSYSGEQSETNDMSFMNTEETENVEISPEIFSHFLLGQDSEESEEELMNCDDEEEIEIEQPDDERPRRLKRRRNGDDSDSSIYSVTASSSESISSDDDDYMPKRGKGRGSIPLTSRVSPKKPSSSTNSKPGKSASSTSKDQMDHKTRLELVKHMQKRPGNIWECTICNFMLSDFSNMLLHIKYNHSTTTHTCSHCRAVVLCRSPKDAMIHEAQCKSRPNIINSRCIPPAPVRKLVKPRVPPARPDDSVNAKVDKFVSDLLNPGPSSSSIPSKNRRTNFRPIIGKVKQKPAGPLAVVTLSSDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBG0</accession>
    <name>A0A1D2NBG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FH2 domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000104">
        <property type="protein sequence ID" value="ODN02594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NBG0"/>
    <dbReference type="OMA" id="PHDGHNS"/>
    <dbReference type="OrthoDB" id="26518at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.150">
        <property type="entry name" value="Formin, FH3 diaphanous domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46345:SF8">
        <property type="entry name" value="FORMIN 3, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46345">
        <property type="entry name" value="INVERTED FORMIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="2">
        <location>
            <begin position="215"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="937"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1185"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1231"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1302"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1339"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1408"/>
            <end position="1419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1419" mass="155938" checksum="9CD6FC9C50A554CF" modified="2016-11-30" version="1">MVMFRHKDSSDLVVQLDVFDEQRESDESQTTPALSGIDLSSPLEVFYAILRQISDSPQEIPFLCILQHLLRIDAKEPISDLIWDAAERLVHRATLLESRDDALRILKSPSRSKSLQKIKGSQTVVTVGDKCSCNCHKSERKGSVTVTLLNADPSEVPVSTEAGPPPPPAPPAAPAPPPPPPPPPGMGGPPPPPPPPGALPPPPPFGAPDMPKLPQQTIPLPKTKMRTVNWNKISSGQVLGGNKNNLWATFAKKHSNTTATLDWAALEGLFCIQTENMKLAQNAAAGVITKAPASTTTAASGGPGAPNPDNKGASPLKRETNEILLLDAKRSLNINIFLKQFRSSNTDVIQHIVEGKSEDLGTERLRGLLKILPSKDEVEMLKSVPKEDQERLGAAEKFIVQLIRLNGYRLRLEAMLLKEEFESCVSSLESSINVILQATHDVKASQQFQDVLFMVLVAGNFLNSGGYAGDAAGVKLSSLQKIADIRGNQPGVSLMHFVAMQAEAKDPKLISFVEDMASLEEASKTSIEQLKSEILGLKTKVVNIDKQIQDPNTPSEISQQFGQIFTDATYHLSALEGFLTQVEEVRLDMAQFFCEELQTFKLEECFKILYSFTSRWKQASIENGRRKKQEQEAAQRKKIREEQFQKRLQLGWETPQTDNNKQVPLNAEDEIFIACSPRVVRRRLGSLSDQANNNLQSPDQLTLPSPGKALDTTPNGSLRRRRSRVPSDEDESGLMDFLRSSGSENLRERKPEQYGSLDRSWSRKARRRPNLMDYLNDERERPVSPAPGHKDSHHNNPTVQIDSCGDSKTEETKSPSSHFIPREWRERIAAWFVDLENGGSGDTPKRRSPPRRFVRRFGEPREVVVGGSRGLATLPEGMHEEHEPVFSTYQRVYADRRPSLKLNTDVVSAMEAIEEVQSPTKERPVARKSIVSLSSMLNNENKRKIGSDRTPKEPAQAKETDGRRSLIGSLGASESHDEKLVLYIPEKSLTNSNGKSIRRVPSVSIADKKEDDYSSSNAGTKEGFDRFASIRRSRRYKKGPELTSSSTPSSPIITGSNTMTNNSGMSSPSITTTRPELLTPTAAIRSRISTSSPSKTEPIRSESMRSSEKPSLKPDSNISSSKSLRAPVRRRHDPRSMSTIEPRDVKLAMKNNATIGSESQAPVVSSQNGTSIVQIRHGASNGAPSRMFSSSKTTLSSSPGTAERDEGFEESHSSLSETNSQSEANIILTKDATSAANGSHSADSRVLQRRPSRTSMTSLNTPSSKGNSFRESNNNVISQNYKNSSRQSLLSSRSSLTSQTTVGTVKESSNHLNESNNKKNGSKSRIPDHLESTYSTHPSTHTGLSSRSSSNGSNHSFSSKTVKSENGHNNNNNNLEKKSSGKGVRIFSFMKPTASSQAKDKIEPPSKSKSKTSIKKAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBJ8</accession>
    <name>A0A1D2NBJ8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphorylated adapter RNA export protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">RNA U small nuclear RNA export adapter protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_04037</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PHAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000102">
        <property type="protein sequence ID" value="ODN02634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBJ8"/>
    <dbReference type="STRING" id="48709.A0A1D2NBJ8"/>
    <dbReference type="OrthoDB" id="20573at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006408">
        <property type="term" value="P:snRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1440">
        <property type="entry name" value="PHAX RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039047">
        <property type="entry name" value="PHAX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019385">
        <property type="entry name" value="PHAX_RNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038092">
        <property type="entry name" value="PHAX_RNA-binding_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13135">
        <property type="entry name" value="CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13135:SF0">
        <property type="entry name" value="PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10258">
        <property type="entry name" value="PHAX_RNA-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Phosphorylated adapter RNA export protein RNA-binding" evidence="12">
        <location>
            <begin position="49"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="213" mass="24370" checksum="ADB18FA359675FB9" modified="2016-11-30" version="1">MECGSSEVQETTMDVQDEEQKQNAPLERKKWKTVLQARFRHLDDNEFGNKMVRYLQEQRNPGVIQKAVQILGQDECLRLLHKTLKIRRSGGIVIKKKTRMRTTGGTFLYLIRNDKRVSSDKKEAVLHDEGLQPSTVRKNVDDKPQKGHHNYGGGITQRIMARHGGMPQPRIDLESDKFSLPSNPAEVHKAATKASTNRTEVSYDDLDLLDFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBN1</accession>
    <name>A0A1D2NBN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000101">
        <property type="protein sequence ID" value="ODN02657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBN1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="13378" checksum="D803FED3075A94A2" modified="2016-11-30" version="1" fragment="single">MLSSKTLTLMATYYSFAFKTHCTPFEWDWGKYFPHLAAEPGILKRDNIEAMVMNVFGIVFMNSAVTFYLFMDSPKSPQFFYSVLHTYLPEHSLHILMDFAILEAFLTLVSWTTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC00</accession>
    <name>A0A1D2NC00_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease Dicer 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC00"/>
    <dbReference type="STRING" id="48709.A0A1D2NC00"/>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051363">
        <property type="entry name" value="RLR_Helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14074:SF16">
        <property type="entry name" value="ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14074">
        <property type="entry name" value="HELICASE WITH DEATH DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="36274" checksum="7A1A273FB02F50D5" modified="2016-11-30" version="1" fragment="single">ILAMSTQILVDAITKGFVRWTQIALVILDECHHAQKNHPMASLMKGYAEKRESCPKDVPKVLGLTATIIIGKSKVADIPKEIKDIEKLLCCKAVTHRNYEEVLRHSTSTQFQIRTYETKYTENDQVCEDITGLLQLLAKLPKNVVTEDEISTIESIDHPSLISEDQLFSKRKGVPQMLKTFLNDLLKTYVELGAVLHKYSIHFERPYCAKLAAVVKMIFILQWIRQISSNSDSDSSDDDDDDYEIKEDEDPVDAVVLLENVLTVLNAFIRRIDNSMKAVALSQGSRSDQEAYIIKHCVSPKIGKLLELLGSKSMYGYVIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGH3</accession>
    <name>A0A1D2NGH3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter G family member 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGH3"/>
    <dbReference type="STRING" id="48709.A0A1D2NGH3"/>
    <dbReference type="OMA" id="TIILWES"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051449">
        <property type="entry name" value="ABC-2_transporter_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30294">
        <property type="entry name" value="MEMBRANE COMPONENT OF ABC TRANSPORTER YHHJ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30294:SF38">
        <property type="entry name" value="TRANSPORT PERMEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="7">
        <location>
            <begin position="4"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="305" mass="34067" checksum="F6A248E6DB5F43A4" modified="2016-11-30" version="1">MHVPIQSAELAKAQVLEGNLWGYFTFPSNYSQHMANLVVEQKFAGNETLEGSRVRLRMDMSSYLGAAIALRTTFEAYENFAKNLAISCGLNEKEFQLPIMYREPVYGTNEASYHDYVTPIVILTVIFEVPMLITTILFISDKKQGTLDRARIAGLKFKEGLIGYILTQGSVAVGQTFICYVVMKVIYDFHVLGSLFAFFFILILGGICGLSMGLLMGIVFKDEIGALMMGMLIGPTIILWESGRKFTNSGAMSSPTTMVCASLRSVISRGWGLFHPQVWPGIAVLGGYTVFFWVISIWLYIRKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGI5</accession>
    <name>A0A1D2NGI5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">14-3-3 protein epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000045">
        <property type="protein sequence ID" value="ODN04381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGI5"/>
    <dbReference type="STRING" id="48709.A0A1D2NGI5"/>
    <dbReference type="OMA" id="KGCQLAR"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="6">
        <location>
            <begin position="4"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="3">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00039427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="29721" checksum="FC451245F26E1768" modified="2016-11-30" version="1">MSDREDNVYKAKLAEQAERYDEMVEAMKKVASLDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESKGGEDKLEMIRQYRAQVEKELKEICSDILTVLDKHLIPCASTGESRVFYYKMKGDYHRYLAEFATATDRKEAAENSLVAYKGASDIAMNELAPTHPIRLGLALNFSVFYYEILNSAERACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGEGTEGTEGGDSEAKEQLHDVDDQDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH83</accession>
    <name>A0A1D2NH83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rho GTPase-activating protein 44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02054</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000039">
        <property type="protein sequence ID" value="ODN04621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH83"/>
    <dbReference type="STRING" id="48709.A0A1D2NH83"/>
    <dbReference type="OMA" id="WMNAIRI"/>
    <dbReference type="OrthoDB" id="19923at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035020">
        <property type="term" value="P:regulation of Rac protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.555.10:FF:000001">
        <property type="entry name" value="Rho GTPase activating protein 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047165">
        <property type="entry name" value="RHG17/44/SH3BP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14130">
        <property type="entry name" value="3BP-1 RELATED RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14130:SF14">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 92B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="6">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="178"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="687"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="62"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="692"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="728"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="785"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="809"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="841"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="873"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="892"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="907"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="917" mass="100337" checksum="7A6B7BCD8FF2EDC5" modified="2016-11-30" version="1">MIYANKWSLCFFNDLNDNREVLGEGGQIEMKLGQAVVEFEIKIEECVLKPLQTILDHDLPNIYKLKRTLSKLTENMDAAKAKLQQASRHSMSTGTTGKIDNIKEEWEDAQQKVEQCRDNLAAEMYALLARESEISRLIVNLLNYQKEYHKSIHDILDELVPGVDAAISSSVHKPVYGEDLGDHLTTTKRKIAYPIELCICGMLETGLDEEGLFRIAGSTSKVKKLKSAFDAGILDLDGLLREFGDPHVMANALKCYLRELPVPLLTADLYDDWMNAIRITEGQEKLKALWTVVQKLPKYNLDNLAYLVKFLKELCLHQDVNKMSPANIAIVIGPNLLWSTVKAEDLTGDNNPMGMNMTMTHHYSSVLDQLVSYCDYFFPDGEQAGTAFEQDLHTAATTGNRTPGLLSNGLSGATHATIDESQELESDMKRSQSCSSVDEHSPPHGSPKPVLRRKNKPAPVPPINPHPTKTSPTPQRNNSTEKDNSAQLTKTNSFNNRNSQQFTEPARMSPSVEKEKREGMWIPPSPSQMVNRKLNLGGDSNRPPSMAPPKPPQPQFDSSRPSRFTNLPVQPNEPPPKPSPLKYKSSFKTSASIDGPPAASEHPSPSRHNTTDNIDSSHNASNAFANSNQFCSLPRHFHTDNSYKNQRAPRAPSIFNAAPSVPPPHPPAPISLPPTNTLISATAVAVTEPEAEERRGSEIHIGFEKLEQEVRKSSTDKSGDESAEEGNKINSDQASVTQHNNNNNNNTKGQTVVPNPPVPMPRVSLNQGGSPPIAAKEQGGNPPTARERPSIMAKPRDLPKRTQSQNKGAIPSSVVVAAPSSANVSHHHELSSGSGGESDNPDGSNASQSTTVVDEGSTVLSEDSVEVCRNGGPKSLPLNQQLPLSPTSRVPYRPPRPHPPPPPKVSTKPSQGESTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHQ5</accession>
    <name>A0A1D2NHQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Drosulfakinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01952</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gastrin/cholecystokinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHQ5"/>
    <dbReference type="OMA" id="CTALCDP"/>
    <dbReference type="OrthoDB" id="6360815at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013152">
        <property type="entry name" value="Gastrin/cholecystokinin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013259">
        <property type="entry name" value="Sulfakinin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08257">
        <property type="entry name" value="Sulfakinin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00259">
        <property type="entry name" value="GASTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0027">Amidation</keyword>
    <keyword evidence="5" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="11203" checksum="FA5A1A7B77C9AA1E" modified="2016-11-30" version="1">MVLLAYTVCTALCDPINGGGGSGTAPSAPHPNARKLRVLNPGLSRMFRMLRSTGISDDDEVLVDDDGYFQKRQYDDYGHMRFGKRNPKDFDDYGHMRFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHX4</accession>
    <name>A0A1D2NHX4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01977</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHX4"/>
    <dbReference type="STRING" id="48709.A0A1D2NHX4"/>
    <dbReference type="OMA" id="HRYLRED"/>
    <dbReference type="OrthoDB" id="10046764at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12430">
        <property type="entry name" value="RRM_LARP4_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058699">
        <property type="entry name" value="RRM_LARP4/4B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF131">
        <property type="entry name" value="LA-RELATED PROTEIN LARP4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26088">
        <property type="entry name" value="RRM_LARP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="5">
        <location>
            <begin position="86"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="44"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="332"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="594"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="431"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="463"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="684"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="703"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="725"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="742"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="763"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="804"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="841"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="891"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="908"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="926"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="986"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="995" mass="105493" checksum="A3AB39FB1ED4627B" modified="2016-11-30" version="1">MGRAYMNGEVGSTTAAFAGEESIPAMVLQVPTSAGAGIIADNRTLNGLKDGTSMPREQMKSIESNEVENADNSRRSDPGNGATSSDMPKEELKRLLLQQLEYYFSPENLANDKFLVSQMDSDHYVLISTLANFNMVKKLTGDQDLVTEVLRESKNVQVHSDGKRVRPVSHRTVVILRGIPESTPVDEIKALFDSENCPKCNSCEFAFNDSWYVSFESDEDAQRAHRYLREDVKEFKGQPIMARIKSRPTTLLAQGAGVHLKNGFHQPTQVMGTFIPPAFVPGSQTGPTTAVAPTPMYAHGQTVPPVFSLPPNYSYSPWPSFFGMGPEQISQMYPLNGIPPQHQSSSTYPKSLPINSRPRNPNQVRPRRPPPSSSDNQGINGVVGAGGTGSAVAAHQSYGNPPPRKPTNNPPPPLLNLVPNPPTLPLANPTSHNHSQSHMTHSSVQVSGAAISQNGRHFNSLPSSHNADSYHPSSSSSGSMRPYRGVGDSRPRSSLSNRKGPPRRDDEGSYDGPSASPSLSAKVPSTRGAPPTAPVAQPPVETIGPHQHQGKLNFDLEGSAFPPLPGSGQSAGKNGDAMFEGRLSDVVKGVKNFKSTSSEKDDAKPSAGNVPTEIVTYVQSGKKEFREVGVGSADDTHDIRSSHYKSSVVSGGVRGKETADKSTRTDEALLNGDQSQGIVGVKAGGASNSSSQTSVSQNGGNRKSASQTTSSKSPIPGKRAVPALQVQNASSTVSVGPEVPYSSRNVTSPVATTPAKISTTVHSIPGSGNIGSNTGNSAVGRGANAYMAKPNMDNNNSRANGTVSNNNGSNLSSVDKDAFPSPGFGKSVPTCKPFPVSTDQISKEVRTDVEKERKESGQGDGKKGDDCSNDERDGPVRLSYAQVAQARKDAVAVSNSSSHTSIASNNVHTASSPNSTSVPHGFSSSNEEKKKPNPKDTKDPRAPAKNQRGSGGGDRERGGFRRGFRNRMMSDHSDGGSGTSGDSSRRLPKPSRSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHY0</accession>
    <name>A0A1D2NHY0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nuclear envelope integral membrane protein 1b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
            <orientation evidence="1">Nucleoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000034">
        <property type="protein sequence ID" value="ODN04874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHY0"/>
    <dbReference type="STRING" id="48709.A0A1D2NHY0"/>
    <dbReference type="OMA" id="SPECKQW"/>
    <dbReference type="OrthoDB" id="509138at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019358">
        <property type="entry name" value="NEMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13598">
        <property type="entry name" value="AT07567P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13598:SF1">
        <property type="entry name" value="AT07567P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10225">
        <property type="entry name" value="NEMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905584" evidence="9">
        <location>
            <begin position="22"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="411" mass="46501" checksum="0242D6E0D77DFE39" modified="2016-11-30" version="1">MASYSLVLCTLALLAGSSVLSNSDEAFTMVHRLDANSKEIEINKNFDIQIFCRAGDRKTPLYYFRSATLRIYSAAEDIKLIKGPTPQDVYDQHKSSTWLFWIANIMPWRMRDASFPTFNTSCVGISTNQLYTARMVVRNADPWKVFLFAVGLILYFMSPKLAKSTLFFYSSATFVGAAAAALLILFLMSRMLPRGRGSYITLSVVYSIFLYFAGETWNRFEQLIQQRLPYVIVYLSLGAVVSIISCYRFGPPSNPKTLNIIQWSLQLVGLLLIHLSSDLVEVSTCLIIGLVSYNLAAEKIMYHAKKLKYRCFPPKPKFLTEEEYITQGAEETQKCLEELRKFCNSPECNTWKVVSRIKDPKRFSSFIEGESHLSDSEVMAYDSETEALEEAAAADLLTDDENGSNVTDDEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIX3</accession>
    <name>A0A1D2NIX3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein CASC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_01436</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Dendrite</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Stress granule</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Perinuclear region</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CASC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000027">
        <property type="protein sequence ID" value="ODN05228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIX3"/>
    <dbReference type="STRING" id="48709.A0A1D2NIX3"/>
    <dbReference type="OMA" id="HPEERHG"/>
    <dbReference type="OrthoDB" id="657902at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028544">
        <property type="entry name" value="CASC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13434">
        <property type="entry name" value="PROTEIN CASC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13434:SF0">
        <property type="entry name" value="PROTEIN CASC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09405">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01044">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="15" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="14" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="12" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="19">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="739"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="336"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="741"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="778"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="828"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="857"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="889"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN05228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="899" mass="99924" checksum="F7C32749DC31D7CA" modified="2016-11-30" version="1">MNKKDKPLDDDEDRKNPQFIPKKGYFYEHDDRTKVEEENGEKPEEPVVKEEKPKKPADSVNKWSHDKFEETEQAPKSSEELQTLYGYDIRSEDQPPRARRRRRYGRGPTKYTRQWEDEEAYQKPRGGYRGRGVGRGNFRGGNRDRRQNSREEYDEDFPELGDSTTKINKIEPSEAKPVNNSKPSATSASAPFPKRSSDKEQQPQPPRQEQTKRGSGGDERGSRDNNGPPIRRDRDVRPNARDYDRENDSYSSRGGGRGGGAGGRGGGNSRRGRRNEFTNRNRYPNRRDYRDDAEYNEVSSNSNTNNSSRQGEGGRSSNNNRASYNNSYEGGGRDGGGGRDRDYSGRDRDYGGGRDRDYGGPKSRPDNNRRGDHHNQSRTIVNGTSNDSRQKPFVNDGKQEKAQQQTQPQQHRIPPFTNTEYPAPGKAGSNVNNRTANNSGPNTSRTINDRQNSSYSEVVDDRHSREPNEGGEPQKEVRDLREKLNAMRMQKGYQGPPTDRRSQIPPRLQQQQQQQQQQQLDPATSKPRRYSTQRERPVQQQQAIVTSGGMVIPNTVAPSIAHGVPNVVPVVTMADGVVPSTVAAFQPPTYYEGTQVYEASASPVTGSGPSVSPSLWTPHATAYAAAPYPSPPTAQVPQVPQPPYGDPTAFIGPGGPAIYAAPPQFLQDPTIINYSGPAPPFPPPYHAHPQGFQGYAQVTPAPPPEVYHGGVTYYSTQNQIQRPPMMAPQKRPKSVLQLVEPPEKSKLDKGPTKDSQHFEHQSELVGMNPIPENSSEAELSKKMEEASLEPRESVERKPSPHREEISWAEEMELTSPTSIYPEGNHFGVQKEESNKQPKQPPPEKEVVVVPPSPPPSEASNNSVNHAAATAAASEPPKDAANKVSTTTPTEEKEPVSSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJE7</accession>
    <name>A0A1D2NJE7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000024">
        <property type="protein sequence ID" value="ODN05357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJE7"/>
    <dbReference type="STRING" id="48709.A0A1D2NJE7"/>
    <dbReference type="OMA" id="FMRFIGQ"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF1">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN05357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="26650" checksum="97AE8848AD435DC6" modified="2016-11-30" version="1">MDLIAKKLMLSRGMKILDIGCGWGSLSKYLAENYGVRVVGITVSQEGANYARERCSNLPVDIRLMDYRDLDEKFDRIVSVGMFEHVGPKNYPSFFDMAERCLKDDGIFLLHTIGVSHDDFPLADAFFDKYIFPNGILPYHKHITEHIDKRFVLEDWQNMGNDYSKTLISWFQNFAQNWNKIESTYGDKFFRLWKYYLLMGAGCFKARRLQLWQVVLSKNGIDGGYYAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK00</accession>
    <name>A0A1D2NK00_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK00"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="6641" checksum="74617B7A5A916166" modified="2016-11-30" version="1">MNFNTKYLICVVFILFIAVTSLVLPATAATKSKRKPKLYNGWCKSPADCGIGDLCVSGRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLT7</accession>
    <name>A0A1D2NLT7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin-like protein Klp68D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_00490</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plus-end directed microtubule motor that may be used for anterograde axonal transport and could conceivably move cargos in fly neurons different than those moved by kinesin heavy chain or other plus-end directed motors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NLT7"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000029">
        <property type="entry name" value="Kinesin-like protein KIF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF50">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="700"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1060"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1139"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1077"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="786"/>
            <end position="793"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN06197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1371" mass="156430" checksum="66DCA9578D8A7B08" modified="2016-11-30" version="1">MINVWHLDLFFLKKILAKFTGKESIMYVFRRLKSLVVPTLVPQQSEKATNDDSGITSNASSRHRSPSVTSHDAAVQCEHDINFNLSRNRIPQDSFQDDDETPTEKALRLFRFKILHLACSMDPTPESLLDRVDPKYCPSPDYDTVRACRLVSKDWNEEISEVFRAAGKPLLIINPLTYLQKRKKHVDPESLLETLSAPLVRPEFLLSENVDLPFPPFKLYLPSSFFYKEMESSFLTAWKTFEEHIYELHFDFPADSTMRFYWPSFHLESLKVIKFKCTCDLRQAMGIIRYLPPNPFQHGNYMYIIQAILNAAPNAESFTLHSYAPQFTPDLFRLTFPSGIQFLDIPLVKMDPKDVEPCLGSRVGNSCCRKNVKHLIIRAPLPTYKNDGNRVTGCHASFLMEEYKQGLETLELATSGKEIDHIIWTMRRDYVYEPLEIEFREPLRKLHTLTMHAGNWEISAMQSYKKMLPSLKKLKLTYISRQSQIEALYKSRSNTVESLNISFIYGLPFEVIEGFANNLPFLRELDIILRDMDESVKVCFQRFKSLRKLHVLCTCSNSNEGRERLNTAVTGIPVEDHKAVLSEDAVLLDVIKKHQNSPSLRDLKDLEELKLIVEGNLQSDVSIMFRATFLRMSKLKRLILSQDTLKISNDQKDYVRKENQYGLDIQWHYENPASDPASGRSSLDLDALLEREASAEPAENIKVVVRCRPLSKKELERKCKVIVDMDVASNTINVTPPEKSSHQPKTFSFDHVFSMISTQADVYNAVARPIVQNVLEGYNGTIFAYGQTGTGKTFTMEGLNEVPELKGIIPNSFAQIFTSIAKAAEGQRFLVRCSYLEIYNENIRDLLAKDQSQFLELKENKEKEVFVKDLTSLVVRDADDMDRVMTIGNKNRSVASTNMNSVSSRSHAIFSIVVECSTTDPGPGKGSLRMGKLNLVDLAGSERLSKTHATGNRLKEATKINLSLSNLGNVITALVDSSSHIPYRNSKLTRLLQDSLGGNSKTVMVAAIGPADYNYDETISTLRYANRAKNIRNRARINEDPKDALLRQFELEIQELRKKLEEESWSPSSELSINKPEEDDDDEGSEEEEDEARIGTGGNTGLTTPEESGETEEAILGIKDELENQARLSSTLGTEAKMRTDALSALKEKENAFKQHEEQKRTLHDRLESLQKKILVGGVNLLDKSQEQEELLQRSLREIMQKREEEKQLQNHLALQEAERVSLEEQIISCQEQNLLLSKKVRKLYNQYQQSKNELHNRKMEYKEEADTLLDSVHKLSKELNYQNVVIDSFIPKNYQQLIEKATMWSEDTGEWSLKCIAYAGNNMKDEDDEAEDVPQEASQVQSVDLSFMYLELDEPPSGPIIDDDVTLHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM26</accession>
    <name>A0A1D2NM26_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">hydroxymethylbilane synthase</fullName>
            <ecNumber evidence="4">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Hydroxymethylbilane synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00723</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM26"/>
    <dbReference type="STRING" id="48709.A0A1D2NM26"/>
    <dbReference type="OMA" id="LWQANHI"/>
    <dbReference type="OrthoDB" id="564646at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13645">
        <property type="entry name" value="PBP2_HuPBGD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000005">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000260">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="entry name" value="Porphobilinogen deaminase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557:SF0">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobilinogen deaminase N-terminal" evidence="8">
        <location>
            <begin position="7"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobilinogen deaminase C-terminal" evidence="9">
        <location>
            <begin position="232"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="355" mass="39041" checksum="FEB6EB424385E923" modified="2016-11-30" version="1">MEERKVIRVGSRKSHLAMIQTNWVVDQLKLQNPEQLFEIIGISTTGDKILDVALSKIGEKSLFTKELELALLDNEIDFVVHSLKDLPTQLPDGLTIAAITKREDPRDAVLFSPQTQAKNLKDLPPESCIGTSSLRRVAQLRKHYPHLNFIDVRGNLNTRLKKLDDPDGPYSALILATAGVSRMGWLDRIGQYLESDDCMHAVGQGALGIECAEANQPILSLLETLNHPSTYLQCLAERSFMRTLEGGCSVPVAVFSAMQHSKREEDAKLVLKGSVWNLDGSKFVIQETNCDVGCNSAISDSESCFKLTSVFLRTFPEFHAQAAIVSAKLGKELGEALLGLGAKAILDEVKAEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNY0</accession>
    <name>A0A1D2NNY0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Metastasis-associated protein MTA1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_00008</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the metastasis-associated protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NNY0"/>
    <dbReference type="STRING" id="48709.A0A1D2NNY0"/>
    <dbReference type="OMA" id="PFWPINV"/>
    <dbReference type="OrthoDB" id="2193595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016581">
        <property type="term" value="C:NuRD complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042826">
        <property type="term" value="F:histone deacetylase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04709">
        <property type="entry name" value="BAH_MTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11661">
        <property type="entry name" value="SANT_MTA3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000012">
        <property type="entry name" value="Metastasis-associated 1 family, member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1240.50:FF:000001">
        <property type="entry name" value="Metastasis-associated 1 family, member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000949">
        <property type="entry name" value="ELM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040138">
        <property type="entry name" value="MIER/MTA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035170">
        <property type="entry name" value="MTA1_R1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10865:SF29">
        <property type="entry name" value="METASTASIS ASSOCIATED 1-LIKE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10865">
        <property type="entry name" value="METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01448">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17226">
        <property type="entry name" value="MTA_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01189">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51156">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BAH" evidence="12">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="ELM2" evidence="13">
        <location>
            <begin position="128"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="14">
        <location>
            <begin position="247"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="640"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="666"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00093454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN06646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="738" mass="82735" checksum="CB74E7EDC6714951" modified="2016-11-30" version="1" fragment="single">FCLKLMNFFFKFQTPNGNVEAKVMCFFRRKDLPPSLTFLADRHQSALEEDEGKERESLSPKQKNILKHRELFLSRQVETLPATSIRGKCSVTLLNETESLLSYINKEDTFFYSLVYDPQQKTLLADRGEIRVGNRYQAEAAAPLLKEGEADTRNSEELETLIWTPDHGLTDKQIDQFLVISRSVGTFARALDCSSSVKQPSLHMSAAAASRDVTLFHAMDTLHQYSYNISAAISALVPSSGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIRSDFLPWKTLKNIVEYYYMWKTTDRYVQQKRVKAAEAESKLKQVYVPNYNKPSPAALSGNKNVLNGSSTPEPLIPGKPCESCLNVMSTQWFAWTGPTGAQARLCANCWNYWRKYGGFKASNKLSTYFTTLEGEVDLIKKPKQPSPEEPVPVVVPIVEQPPPQPAVERAPGAPGIIQPRIHRCAVAGCGKEFKMKNQLARHYAQNHGYSMRSGSPRPVMKTRTAFYLHTTPMTRVARRLCGDILKTRHAARAPFWPVNVMMIKQECQQRVTGKLPEELKQLVTGRKRQLPDAKVSEVAHTLGQSDRVTPEWLILTEKSKMPQPDKVAFPKPPKGPDGTLLYEKVPDKVVAIVVNNLSPSSLAKKRSFEEVNGVDGPPTKRQAWDPTTPPASNPPRSSSRGGSPLPLVSQHLPASSNMNIRNVLNHMNGNSKSKLASVTRIGSRKQIISWMDAPDDLYFYSTAATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0N5</accession>
    <name>A0A1D2M0N5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RNA-directed DNA polymerase from transposon BS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_20156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008426">
        <property type="protein sequence ID" value="ODM86526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0N5"/>
    <dbReference type="STRING" id="48709.A0A1D2M0N5"/>
    <dbReference type="OMA" id="FPSQWKH"/>
    <dbReference type="OrthoDB" id="445826at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33332">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="81"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="492" mass="56214" checksum="1A3DDBC0BEBFD795" modified="2016-11-30" version="1" fragment="single">MGFPPGEPVVDTIGNERAERPADDNYFYVKSVSQLEVCKAWKGLRRKLSKRCDTCGISKFFLDKIILMPAYLLLITTFVNLCFEKGEVPDMLKVARVVPIPKKSGAILPSDFRPISLTSILLLLLEKIYYNKLVGFLEKHKIMSPSQFGCRKHHSTELAMITATDYIRKLIDSGLIAVIVSIDLRKAFDSVKRGKLLRKLLKKYKISDYWLRSYLANRKQFVEVNGKQSEIRDVLIGVPAGSILGPILFALYVNDLPDSVKSGITVMFVDDSNLVFGGHPSKLGELELKINADMRNVCSFLEESSLVINSDKTKMLTVSSSRRCSLLDNFCFDLNGFKVENSSTLKCLGITLDRKLNFRTHMDNVARLCYARMRALYTIRAYLNEDQLRILSQSLVYSMINYMVVVYGVTSAVHLKVLKRVVRTLARLVFSLRKYDKVSKKMYEELEWLVPQELCQFNSLCVMFKLSKETKVDAFNEYFVEKPTHGRDTRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1C6</accession>
    <name>A0A1D2M1C6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_19934</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007384">
        <property type="protein sequence ID" value="ODM86752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1C6"/>
    <dbReference type="STRING" id="48709.A0A1D2M1C6"/>
    <dbReference type="OMA" id="FCPFAIR"/>
    <dbReference type="OrthoDB" id="7633403at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000016">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="17"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM86752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="123" mass="13701" checksum="44C288B5402D4FA7" modified="2016-11-30" version="1" fragment="single">MPPKASGKVVKKAGKAQKNISKGENKKRRHKRKESYAIYIYKVLKQVHPDTGVSSKAMSIMNSFVNDIFERIAAEASRLAHYNKRTTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1V4</accession>
    <name>A0A1D2M1V4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ subfamily A member 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006724">
        <property type="protein sequence ID" value="ODM86937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1V4"/>
    <dbReference type="STRING" id="48709.A0A1D2M1V4"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="22"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="16899" checksum="8B43FD8128C81276" modified="2016-11-30" version="1" fragment="single">MNILFQFPGFDQTNSSKAWRNWVLRYTEVKPSCTPEELKKAYRKLALKFHPDKNPNEGEKFKLISQAYEVLSDPQKRRVYDEGGEEAIKGSESGSSGFSSPMTRCGQASRVRRAKNVVHQLNLTLEDLYNGTTRKLAVHKNYTAKNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2P6</accession>
    <name>A0A1D2M2P6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative N-acetylgalactosaminyltransferase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005811">
        <property type="protein sequence ID" value="ODM87240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2P6"/>
    <dbReference type="STRING" id="48709.A0A1D2M2P6"/>
    <dbReference type="OrthoDB" id="5988548at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="119" mass="13448" checksum="2048D71AF0408A1F" modified="2016-11-30" version="1">MTDNALKSAKNARDIHVVIGYYQGNNLPWVHNENITEEILNQNMYSPDPSAGRNGEAVIIPSFESPKMNKLFQINRFNLMASDRIPLNRSLPDVRRKSARVGAIKCLSYQRPASSLFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2V2</accession>
    <name>A0A1D2M2V2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-xylulose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19396</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005669">
        <property type="protein sequence ID" value="ODM87286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2V2"/>
    <dbReference type="STRING" id="48709.A0A1D2M2V2"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="419" mass="46584" checksum="5DD66895A3697647" modified="2016-11-30" version="1" fragment="single">ADERRCQSCSSLEPNRGRKMMRRGNLRAIVNISSISGKRAFSKCWCLLYHQSSAGHVTKVMAVELGIHNITVNSVTPAMVDTDMAKNFIDKMAQTTPSEVGRGCETSMASRSVSNETYIEMKEVVNAVLFLASGENRQISGTDLCVDGGFLIIKENYLLKYKMSFTGKRVLVTGAGRGKEKLEYSVQNFFRVNKISSLPIQESDVKIVKELHCQGAKIYALSKTQENLNSLLEELSTNVIPICVDLGNWEQTEKALENVECVDVLINCAAFAEVESFLELQRSNLICKYLTYYANIYYKSLQLRIYLIVFGRQMNVNVKAALHVSQIVARKMIAEGKSGAIVNISSIAGKRAFQNAGVYSTTKAALDMLTKVMAVELGPHNITVNSVTPAMVDTDLIRTVLFRKCKSCECIDGRVYKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2V4</accession>
    <name>A0A1D2M2V4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005687">
        <property type="protein sequence ID" value="ODM87274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2V4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903409" evidence="2">
        <location>
            <begin position="20"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="18839" checksum="5B0F9B02AC508FFE" modified="2016-11-30" version="1" fragment="single">MKYLGVLLLVLVSQEFCMAITVPNEVTRVDRFQHPSYNGVSMKPVFPFRRQDDDNSSNSNISISNDDSSSSDGKSQDLQIPTINFYSTIPNAIGVVGQGFLWIREVSAAIGTPVAIYVMTPPMLLLGVGLIFMPDLTGLGLPLFYPGGGDETESLTFGDLENLDFLKQAGELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2Y3</accession>
    <name>A0A1D2M2Y3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005621">
        <property type="protein sequence ID" value="ODM87304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2Y3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="14965" checksum="2A6E06727A195C96" modified="2016-11-30" version="1" fragment="single">MNKSGTSGQTQVAIDSDQDKIPDDQGETLEIFTSDSESELGAFQRFRKSSEGESSIHIHYQKRRKRKKTSSDSSTSSSSDSDTSESEFQKKKEKIAKPTPSQKPNPNLILHSCRLCRDNPGFSSKELSTSIGNHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M364</accession>
    <name>A0A1D2M364_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sex peptide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005375">
        <property type="protein sequence ID" value="ODM87415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M364"/>
    <dbReference type="STRING" id="48709.A0A1D2M364"/>
    <dbReference type="OMA" id="FIMYCTM"/>
    <dbReference type="OrthoDB" id="5864054at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019427">
        <property type="entry name" value="7TM_GPCR_serpentine_rcpt_Srw"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053219">
        <property type="entry name" value="GPCR_Dmsr-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273:SF4">
        <property type="entry name" value="AT19640P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273">
        <property type="entry name" value="MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10324">
        <property type="entry name" value="7TM_GPCR_Srw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="69"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="44360" checksum="11E68A80A0564162" modified="2016-11-30" version="1" fragment="single">MEEATSEFPIFELNTTNLNETFDADNASRVAVTDNSFGYCDSYLKPFAKSYSTLHGYNSLIICLFGAHANILNLIVLSRKEMRNPTNAILTGLAVADLATMLEYIPFAIYRILLPKTNSYEWAAYVLIHSNFSQVLHTTSIWLAVTLAVWRYVMVTRYRESKSICSMKRAQKAVIAAYIFSTMAHLFISFAVKPIQSVGEKENSLIYVVNVSDLAIKYPMLKTTNFWLYSVVIKMIPCAIFTIVNCHLISSLERVKIQKSMMFPMRAVHADIIERQAGRASFSFEAFGSDSTTRMLLAVLFLFLITEFPQGLLGLMSGVLGDEFFNSCYIPLGDLMDFVALLNSSINFILYCTMSEKFRETFIKVFRLNGIVRLFRRQSTNRKSYEDTHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3W1</accession>
    <name>A0A1D2M3W1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004879">
        <property type="protein sequence ID" value="ODM87668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3W1"/>
    <dbReference type="OrthoDB" id="7544260at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="314" mass="35894" checksum="4AB8D8E413F31005" modified="2016-11-30" version="1" fragment="single">GRILVLNYLFTPKTQLLDAWLSGNTEIQVADRDQGQTENNTEQDVSNRWATWENGVVNLTLKDTSEVQKAFDEYTKRPASGFNLGRKETLTLWSAGCQVWERLSQHENDGSSTWPYNLSWSRASASRSRPVFKLFKLQLKSTQSGKYETSHELVRLHKSTTFQVWYMREGMPIQKWIDPKWTKYIRCGPDASPGLSVLDVDNINYLYNCQGCQRHRWIPAASLSHEDFSNMPTFGYESENKNPIFACRAQHQAEIVSGMYDHASKTCKLSWANKPYKISDTFEILTIPGGVVGNDCSVYKPPYGTGRPTLRMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M401</accession>
    <name>A0A1D2M401_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004868">
        <property type="protein sequence ID" value="ODM87676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M401"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="30068" checksum="8ED923319DC83DE0" modified="2016-11-30" version="1">MQDEILDDGSSTGVQMLWTLWLKTVEGMFANISDTGCDEAWYDPDLMDVPDCFDPLMRWFHGIFEIMMVIMFIQSGLWIIAMIFASIHFAAMKYEQEAPERTFFAVEKANKHEDLAWARPSNHGNVDEKGGTKGDEAQTMLQIQKDTSDHHRHSKHSKKHLSGNSEKSCGKASHHLPASVFQVSILLLAVFVAIFAFTQAYPHPAENEAEALSDFESEMAEGLDNEVMDFEAFAAAGDDSTGSSKKKRKSKSKAAKRRKGQAKTEAPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4A8</accession>
    <name>A0A1D2M4A8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004714">
        <property type="protein sequence ID" value="ODM87774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4A8"/>
    <dbReference type="OrthoDB" id="8294900at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="106" mass="11953" checksum="91FDA84DC636DF93" modified="2016-11-30" version="1" fragment="single">KSDIFQGKKLARDLWEKFEDAGRLKQVAILTALTAAFGLLAVGSTTLLSFAMPAAFVASTRYFNEVSAHHFLLKQEVSFNLLHLHALHAKPLSTAWAKQYVLWKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4X8</accession>
    <name>A0A1D2M4X8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gonadotropin-releasing hormone II receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004226">
        <property type="protein sequence ID" value="ODM88029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4X8"/>
    <dbReference type="OrthoDB" id="6435638at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="139" mass="16026" checksum="CD84B584C4D2E2EE" modified="2016-11-30" version="1">MRSVGVTLFLASRGFHMQTHVIYPRFWALGYWLRNRRLQPGFIFCGGKTHENSLRRPTGKGYARHSLDCSLPAAIVGHVEKFDCYDECVYQNFCLSNNPLRRSNTDGLSRARVRTMKMTVTIITTYFLCLAPYAILVVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M572</accession>
    <name>A0A1D2M572_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004092">
        <property type="protein sequence ID" value="ODM88118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M572"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="111" mass="12541" checksum="AAB2B9BF2BB3677B" modified="2016-11-30" version="1">MDVQHAGVGVDIDELLKEAVKMDVKDKSSLKILNAEGKRVRGGGTGIKSRSRRVPTAKRRRRHVKQQSSEDEELCGEEDESVQKDSAFEKQLQIRVISLDKKISEYKMNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5F1</accession>
    <name>A0A1D2M5F1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-actinin, sarcomeric</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18485</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003978">
        <property type="protein sequence ID" value="ODM88198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5F1"/>
    <dbReference type="STRING" id="48709.A0A1D2M5F1"/>
    <dbReference type="OMA" id="AHANEVQ"/>
    <dbReference type="OrthoDB" id="18853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000004">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000003">
        <property type="entry name" value="Actinin, alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000148">
        <property type="entry name" value="alpha-actinin, sarcomeric isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014837">
        <property type="entry name" value="EF-hand_Ca_insen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08726">
        <property type="entry name" value="EFhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01184">
        <property type="entry name" value="efhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="289"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="330"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00067262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="435" mass="49335" checksum="35D022E112A0A3A2" modified="2016-11-30" version="1">MTATLSISDAKEFVINGTGLAPLLRNEGQGIDETEKILEKLIHCTLSSPNGCYLWVCLSTTGLDGTSEDLVDMFIVHTIEEIQGLIDAHNQVSPTFQGNIGRKPIRIQCNRLLGQGSGEHRLRNTKFPEAWRIPTLLSLPVSLRRNGPMCDNSFPQRDGTLQNEFRKQQNNEMLRRQFAEKANQVGPWIERQMDAVTAIGMGLQGSLEDQMQRLKEYQQGVQAYRPHIEELEKIHQAVQESMIFENRYTQYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGITQEQLNEFRSSFNHFDKNRTGRLAKDEFKSCLVSLGYSIGKDRQGDIDFQRIMAAVDPNNSGAVTFDAFLDFMTRESTDVDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMSPFKGAGAVPGALDYMSFSTALYGESDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5N8</accession>
    <name>A0A1D2M5N8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_18385</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01003810">
        <property type="protein sequence ID" value="ODM88297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2M5N8"/>
    <dbReference type="OMA" id="HEERNSC"/>
    <dbReference type="OrthoDB" id="7692176at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000003">
        <property type="entry name" value="Transposon Ty3-G Gag-Pol polyprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018061">
        <property type="entry name" value="Retropepsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00077">
        <property type="entry name" value="RVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peptidase A2" evidence="9">
        <location>
            <begin position="486"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="10">
        <location>
            <begin position="1302"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1615"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM88297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1758" mass="200581" checksum="2DF7C01820113E3A" modified="2016-11-30" version="1">MVGTRRSQRLGVEDYYEVESQASGRKNKKRRQSKQKVRKSKEIEVESDDSDNQNDQQQHDLNSVQRDNQTVNQTDIHDEDNSTNKQNDDTGVCKGTNSDALKQMKSNMDDLYKMYVELKDRQEQQTSLDEKILNAFKAYDSLKCSKDQDEEIPMKNLKIRTDIPIYSGAQEAKTPFDFLKELEAYKSVVNCNTKEMFSQVLPVALKGEAYSWFVFARDDIISWGDFVTKFRNEFQPVGYYEELKKELGERTQGTREPLTHYIRIILEFYERLEGDYSEKEIVERIINQMHPQYRFLITRSGQVHFSIQELLKEAQIAQESIYRDRQYKEPKAFINVEPSLSYKTATASNTKSAELEIKESSFDRFRHFHKSVPNSFPSITGNINSYSNAQRYANNISQIHKSDMKQAPTPYTDRKFYNAPPSNVRQATGTGFEGKRVRPGSLIINRSARATSQQNYRRNENDPQDENLVIVRAEPIMKVSICNRSFPALLDTGASLSFINKEIIDILRTLNIKTTQCDRTIMTASGSSKIIESVFLTIEWPGGKKRHTLYLLPDLGRPVLLGRDFISSCNIVLDIQGGGWKVGLGNQELVPFSNDNDRQQMIGHEVPSSEHAISTNKHGGEVTLDSSTFNNYPPVPPGASVDARAGYHVHKGAQVNTGVAHKHDKNMIGLIDEVCLVYEDMLLVSDPNTRPEGKNEAAGENSGQVHDKIADLNLPHDQKRRLMELVDRNKALFARTPGTCPDYRHRIITGNTRPIKHNPRPMTEAKRKILRKCLDDFVEKGSVEESSGAWAANPVLAPKANGKWRLCVDYRSLNSVTESDSYCMPRIDEILACLGKAKYISVFDVTDGFHHIVMDDADKNAPASFQRMMDRALGDYKWQFVLAFIDDIIVYSNSFEEHLQHLELVFKRLLEFGFRIHPDKAQFLKNKIKYLGFVIENQTVSPNPEKLKALEGYQQPKNRKDIQRFLGFCGYYRHFIKDFSTIAKPITELLRKDNVFFWSIDAEKAFQTLKTELARASSLKLPDLGKPFIIQTDASDIGIGAILLQEQESILTPVYFHSRTLSQAERNYSTSEKECLAVVDAVKKFRPYIEFTHFSIETDHQALCWLKRLKEPTGRLARWSLELQGFDYEVVYRTGASNRAADALSRAASLYLIDVNSISVEDIRTAQTSDALLGGITHYLRNRSTRPDDAGEQIIKRSSDCALSEEGLLLRYVANRDKPWEDDEMHWRIWLPESLVTQIISYFHNTAISGHLGSSKTYKKIADRFWWKTMKKDIYFYIARCETCQKTKVSHTAPIGIGSSLKITAPWETVAIDLMGPYTRGTNQNQYLLVVVDSFSKWVELFGIRQATSKVIISRLEELFCRWGFPKYIISDNGSQFTSREYTAWCEKLGIKPFYVPPYHPQSNIVERYNQTIKNMIISVINSCKDWDKYLNELAFALRSSVNDSLEYSPAYVNFGRELRYPIDNNIGLPVMRSNANEISDRIAHIQGLVKENMLGHQERHLAAYNDGRRQGNLKVGDKVLLRTFILSNAEKKITSALCKKFEGPYSVVRKRSESIFDLKHIEYSRLYPLVKKLAKKGKTINSGSKFELVASLLPKDYENSFAPLHHPYPYEREERSGESVCGPSSISAHEERNSCKDGHFEQCRESGTFIPKPKGIPTSSSNHEVDYSRFMIAQTIFGKDVQPTVENGNAQKTVPIGNKPGNAQKTVPMGNKPADLTCMSLEEKNNFLFGSPPQKRTRLEVLAEDLHLSDTDSETGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5S1</accession>
    <name>A0A1D2M5S1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003865">
        <property type="protein sequence ID" value="ODM88261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5S1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="16205" checksum="1141EB486279D8DC" modified="2016-11-30" version="1" fragment="single">EFKIAVSLGEDKLLKKLHHVASSQGDGTVATEAAFRIMARKTRSSSSESGRSSSPSGSTCSCHTSSGMSDLQSISAELEPVSVTIPRTDMIVLEPPSPYRNPITTNTSNAEVENTQQVTGNTEINEDTTLHTPKLEEKNVEQIQVVHLGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M929</accession>
    <name>A0A1D2M929_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chondroitin proteoglycan-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002616">
        <property type="protein sequence ID" value="ODM89478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M929"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37333" checksum="30F18553D485C507" modified="2016-11-30" version="1">MEAGVQYLPSHNCTKYSVCINGKEFEAFCPRPLYFSSEFQRCDFPENVAECKRGTRPPVISQEEYMQTEIPTEITSTSIASTPKPGFLFECGQTIVANSGTIEYKLYENYDAGELCVFVVRSRNYSSFDFVLERHGISDSDPDAITIMGMDNTYGWGIYDTNRIGPPDPTPFIGVKANEAVVIFKTSTNNGTGFRLNYECRGNPTDYPPGVEVVFNDEEDSPLQVPYQSFNEPSYNYVVLTSKSRMISEPDSFLRLTVSGNFENTGECTRFFKIYSFAGGNAVLEGTFCGFDTDQTVYETKGLFVVAYSELNPIATGTLSWEKVDVRTDKMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9B6</accession>
    <name>A0A1D2M9B6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002544">
        <property type="protein sequence ID" value="ODM89560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9B6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="396" mass="46158" checksum="A7AB22F4BF6F7952" modified="2016-11-30" version="1">MTSNKYDIPDEWKGKIVISKWEQHGFSVKDRHTARFNRLHQASKRPHPIPFCGEHFNSDDDDNWDAKDPEEEVDAVGGSDDREDGERLVDMNCTIRPRVPENWKDLQKEDGIKRDVVGDWTRADFAPIKMVNVNVATTMKHPSHVLIVNAMYSVRLQNVVSPTDFFLEFILEPPNDGCATWEESLQQFYNDPERAKKYQMRTIRPFFQQQYAFYNEDTKKWERLLVHVICLQTQCVTAFHLERVEMVRVPFKSLFELHPDYANWHRCPIKGALLDVFPVNPAEPNPSQWSEEACEFFCNFVKDKTYWALVAEKSPPVAAVEGMMPRRLEDQFMGATVVLFERGKKPTPPVNAWLIQKGYAYGKTLMSTSLEQMRDFYNLNLSVEDPFKKTTVVEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9K1</accession>
    <name>A0A1D2M9K1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BarH-like 1 homeobox protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_17063</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002495">
        <property type="protein sequence ID" value="ODM89619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9K1"/>
    <dbReference type="STRING" id="48709.A0A1D2M9K1"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050848">
        <property type="entry name" value="Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333">
        <property type="entry name" value="HOMEO BOX HB9 LIKE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333:SF5">
        <property type="entry name" value="VENT HOMEOBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="38"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM89619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="21147" checksum="4E25AEC375C51ED6" modified="2016-11-30" version="1">MNTIHDYSLHASQLLHSSNDCPDSPMKSREDDESGHLKKARRRRTAFTHSQLAFLERRFRMQKYLSVADRSEVAEVLNLSETQVKTWYQNRRTKWKRQNQNQQLLLQESKPLVVEEAFSGEDGISASTGESPQPTLQNPFMEMSTSAYLSNIFKNFQTNPALACILMHTLPPELLNPTYSNGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9U4</accession>
    <name>A0A1D2M9U4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heterochromatin protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002397">
        <property type="protein sequence ID" value="ODM89756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9U4"/>
    <dbReference type="STRING" id="48709.A0A1D2M9U4"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00034">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="64"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="13883" checksum="4A8DC98E51031D3F" modified="2016-11-30" version="1">MRISDVKLKEEQPSTSRKNGAQILKDEVSSIKPEESSGGADDAKDRDETGADVKPEMFGFDRGLEADEIIGANNENGRINVLIQWKGNNGMEMVPSSVARFRCPDILIKLYEKNLILVASSNNDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBG5</accession>
    <name>A0A1D2MBG5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_16370</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002043">
        <property type="protein sequence ID" value="ODM90310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBG5"/>
    <dbReference type="STRING" id="48709.A0A1D2MBG5"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903760" evidence="16">
        <location>
            <begin position="18"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM90310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="492" mass="56142" checksum="536B52FF86ADC02E" modified="2016-11-30" version="1">MILEFILVLVTFSLLACLSFRKRGKLPPGPTPLPWIGNIHQIFGENVHLKFSKWSKEYGRLYTVQLGNRKALVISDPALRNLFNIPASLGRYKTELFNVIARGPYGVVNTEGKLWSEQKNFCAKTLKSFGLGGSRTSLEPIVLKEIDDCLNDLHNELESSENGVASVLSYIKRYNCNIMWKIISSGENECDNRASALSRDYLEAMARAVTTGLAFVPLLKYVAPEWSGYNSLKRAADNVHVLVTEQFNERKKNFVQGTAKDILDAYVEKLGSCDDTMSTFYGDYGLKNGISAMLELVVASGETTPQTINWLMLYLAHHQPMQQKLCEEIDRVIGKERTPSLLDRQNMPYYEAVLQESLRLSAMVWMSIPHELMEDIEFEGYSLPKGLILLPNLYYMHHDPEIWGDPQNFRPERFIGDDGKFIRNDVMMPFGCGRRLCFGEGLARDMMFLFIVRFFQAAKIYPETPDTQPDFRAQFGFLLNAQPFKVAVKWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC07</accession>
    <name>A0A1D2MC07_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lipase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16181</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001931">
        <property type="protein sequence ID" value="ODM90503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC07"/>
    <dbReference type="STRING" id="48709.A0A1D2MC07"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903790" evidence="8">
        <location>
            <begin position="23"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="9">
        <location>
            <begin position="70"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM90503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="463" mass="52669" checksum="4B0E35F9CA64A490" modified="2016-11-30" version="1">MGHRKTTIISFSFLVVILFSSSYFPDLNKIGGRKCPMYRPYKPIFSFHSGKECHQRSSEVFTNLSTLEEINFRGYNATKYKIQSEDGYISTIIRISGGLKSPARSDNKSVLLFHGLGGSSANWIIQRGDRNFAFILVKSGYEVWLADLRGTSSSMGHTHLDPDSDLSYWNFTIDDIGTRDLPLFLDLIKNETGIEKVYFACHSTGCAVWLAGLAELPELNERFEAGFLLGPASYLGAMYNPMILLYIAMFGTPLDELLSTWMKGRISGEPSYFAKMLGLTPEKVCGSWSFMRCGICDNLFFATFGNDEAQMDYENLPNIISKMQDNIPYGLLRHRMQNGINCTFRKFDYGVEKNLVKYGNKVPPIYNLNGIRVPTYIFYGENDNLVTRLDAEKTRNAIPVQFMRGFYQVEWPLFTHPDFIMARDADIFVYNKILNIMMKSDNEGKCDVVHNITKQKCESPSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCU1</accession>
    <name>A0A1D2MCU1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001795">
        <property type="protein sequence ID" value="ODM90783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCU1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903837" evidence="1">
        <location>
            <begin position="28"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="16704" checksum="A24F6EB0283CE588" modified="2016-11-30" version="1">MHPFSKNLLVLMLLILMFGGEHRSVDGNYTAREMSHVHRQPCRSSGPDCDEDHTGKSVDCMTACAMIKRGDIITKRCEADIAIWKDPDGTFKCIKDKECYCNEDNCNKPKDFGRSGVMILILLNASGWRKDFVPATFILSWIMILVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD54</accession>
    <name>A0A1D2MD54_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001762">
        <property type="protein sequence ID" value="ODM90879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD54"/>
    <dbReference type="OrthoDB" id="5585231at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="16783" checksum="C181DE52AC58C43B" modified="2016-11-30" version="1">MAAKDVSPVAPHPEGKSFLASPVSPTAVCKKEYPSPVTPPEDQSFVQLSSNSRGPSPERGTVAIAASNAAGVVVPPAGIARRLARSDRLDTKRYYTAGVIEDIKKENSADKDASIHKRHSWNYGPQSQNSQHQLAADAACAEKSSLFQLRKHDQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDP4</accession>
    <name>A0A1D2MDP4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein pno1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001656">
        <property type="protein sequence ID" value="ODM91138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDP4"/>
    <dbReference type="STRING" id="48709.A0A1D2MDP4"/>
    <dbReference type="OrthoDB" id="1932641at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PNO1 second type I KH" evidence="2">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="7012" checksum="3B03DC145801FC8C" modified="2016-11-30" version="1">MRKNQVHATKTRIVLADSRIHILGSFENIQLAKRAVCNLVLGTPPCKVYGTLRSMASRASNKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEA4</accession>
    <name>A0A1D2MEA4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ceramide synthase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001605">
        <property type="protein sequence ID" value="ODM91285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEA4"/>
    <dbReference type="STRING" id="48709.A0A1D2MEA4"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="29095" checksum="F9A7914ED374F549" modified="2016-11-30" version="1">MIFQTLLTSLSQFYWSPWFWLPENVKWAQLNPQSDKRFANVSDVYAAIISAVSLLAIRFFLERIICKPIGTFLGITEAHKKLTKFSECGWRFVYYTVSATIGICVLWDKPGSGIRFPLMFGGTAGSALVLSRLSHYGFYGCEEEGFPVRQNLQLCTLPQNGYKSLRTLCPHLDCYTIGVVCCSALQHAVPSFNPNAIVSCLLCHRVCGYDPFWIHLYWTNLLWKIARQSSNDEVRDDRSSDEEDDDEGNGSEEKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MES4</accession>
    <name>A0A1D2MES4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001545">
        <property type="protein sequence ID" value="ODM91443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MES4"/>
    <dbReference type="STRING" id="48709.A0A1D2MES4"/>
    <dbReference type="OMA" id="CEYQIAR"/>
    <dbReference type="OrthoDB" id="6736570at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903907" evidence="1">
        <location>
            <begin position="27"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="102"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="284" mass="33293" checksum="7ED633C7DE64F741" modified="2016-11-30" version="1">MQITMKYPIFLVAILSVTLRSWLVSGVSVEEDLTLTASQKRALDRFKAKVINKLPENFMKQDIYLIRFLRAKSFDVNMAENLLLDDIKWRKENSISRIHEEDFSDVEEDYKAYVESFDREGKPIITANFGDWDIRKAVISGRMRRLEHYIDRTFEIATRKVRQLQAQGKNVTQWDYIINMNNYNVLQHGCVPCLPFYIYLVNSYEKHFPGNADKIMLINTPPVFEVVLSVIRPLMSPLTRRALKVYNQDKSQWQPQLFKYVSPSELPPEYGGTKIYTGDFEIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEW1</accession>
    <name>A0A1D2MEW1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_15134</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001508">
        <property type="protein sequence ID" value="ODM91547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MEW1"/>
    <dbReference type="OMA" id="TNLYEGF"/>
    <dbReference type="OrthoDB" id="10070999at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06705">
        <property type="entry name" value="PDZ_MAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000012">
        <property type="entry name" value="microtubule-associated serine/threonine-protein kinase 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1480.20:FF:000001">
        <property type="entry name" value="microtubule-associated serine/threonine-protein kinase 4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000008">
        <property type="entry name" value="microtubule-associated serine/threonine-protein kinase 4 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1480.20">
        <property type="entry name" value="MAST3 pre-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015022">
        <property type="entry name" value="MAST_pre-PK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023142">
        <property type="entry name" value="MAST_pre-PK_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF414">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08926">
        <property type="entry name" value="DUF1908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140482">
        <property type="entry name" value="MAST3 pre-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="190"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="12">
        <location>
            <begin position="850"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="334"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="602"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="760"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="938"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1015"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1161"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1255"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="626"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="644"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="724"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="817"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="962"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1015"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1047"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1091"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1124"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1190"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1216"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1270"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1302"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1346"/>
            <end position="1367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM91547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1367" mass="148335" checksum="07EEDDC68FCD4AD3" modified="2016-11-30" version="1">MLCGSPLDSPRMSPSQHFAFAAVKRAGDGRRWSVASLPSSGYGTTPGSSTVSSQCSSQERLHQLVRDGAQAAVAEDRAGPLPRHFSSNESNPSLEEEGHRSPLLRPRSRSLSSPIRSPVIENEIVLMNTMYKERFPKATQQMEEKLQGFVEENQTLESMGGCEKLSPDCIAIARFVHHQVIEMARDCLMKSQEKLISSRYFYEMSENLERLLLETREKSPEAASYLAGLVKKLLLMVSRPARLLECLEFDPEEFYHLLEQAEGQAKVTQGVKTDIPQYIISKLGLNRDPIAGTVSNGFLNELSMFFKTIFDTFQLPVRLSSLAELQQELNTQGKEASASAISESGSGCSSKNAGGTGEGSDKKPKLPSEQDFEVVKLISNGAYGAVYLVRHRDSRMRYAMKKINKQNLMLRNQVEQVFAERDIMSFTDNPFVVSMYCSFETRSRPKLSLGHANVHIIFFTVATNLYEGFIDRETRQFSDKQVFGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFIIGCVPFFGETPEELFAHTVNDDIEWPPDEEWPISGETKDIISTMLQHQPRDRLGTAGAQEVKDHPYFDGVDWNSLLRQKVEFVPTLENDEDTSKSQTRTRLAEESQDLQDSSGTGSDWSTGNGSNTGKTPQSSNNNSGAFSTTEVPTPVKKTEAVSGAVAKLSRQSSEATPVATPITHLSTPESSQTESEDISPQLHRRRRAHRDALPRFSISSSSPSTMSSELKGINFSSSLKLDASICKTPEPSSGVLVPIHQSTPKSSEKADQEATTASPRNVVKSASAVGLSLQIPSDDMPSFMISSQAVQSPGGSSTASSRDTSPCRELSPLINSLKPPIILRKGPQGLGFTLRAIRVYFGDTNVYTVQHIVKEVTEGSPAFEAGLRPGDLITQVNGEPTQGLLHTQVLHLLMSGEQLTLRATPLENTSIRSGGRKREPGQSKMAKTPLMKGRKSKKDSVEKRRKSLFLKTLAGKRTPAEIQQLKLSLGTSTIAPSRSFQSLAKSVENVQQPSLPGSPTKSRSSQSPPLPRIFSLSDSPHSTANSSPSSSPGSSLPDSPATLGPSGLLGPHFQRPSSLHGLKHKLHHHTSSKNIHSPNRRKSVGHIPLSPLARTPSPSPISSSPTRSPSPLAVCTNVQPVAGVSFASTSTLSPASVAAKKPFSRTKNAEPGSPLLRRALSPDRHHPRPTEVKAISPLCNPAPKVTISSPPKVTFTSQPHGSIVSKTSTTVSTVSSGLASEALRRSRKDGRVEVSDCDLSKSGSTISSVSDSSNMVPSSSSLSSVSMVLPRIAEEKDSPKEDHITESIAEPSPAGTTTKPETKGVEPQTTVKTNTKKVPGSPDKSGKPSPTKPSSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFJ0</accession>
    <name>A0A1D2MFJ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication licensing factor mcm5-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001430">
        <property type="protein sequence ID" value="ODM91755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFJ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MFJ0"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM OB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="73" mass="8013" checksum="B8F018CC55E4CE8F" modified="2016-11-30" version="1">MCRSCRSVLPNIAVKSQAWKVMPYLESALPNQGAQAGSVKCPLDPYFILPDRCDCVDFQVLKLQESPDSVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG23</accession>
    <name>A0A1D2MG23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14849</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001406">
        <property type="protein sequence ID" value="ODM91832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG23"/>
    <dbReference type="OrthoDB" id="3565419at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="570"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="598"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="628"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="163"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="672" mass="76443" checksum="C1778B9A64AEA527" modified="2016-11-30" version="1">MNYHNSKSYSYSTSSDEEKISVRVDSCLLCAQVAITYDCEGNVIKQEPCSEFEEVRKPNWSNDQLFLFLCRSFDLEKKKNYSGLQLDPFPFCGLCELLINSLGDVYTKLDELKNVLRGKIEKAEEVYLRDNLYEKHSNEYLVFRKDALGVAWKNPRKVLESRKRLTSKWNSSSKGASKSRANETVSETPSHVEVPDSEGSRYSSRVLRKRTSPLKYEEPSSEDEVDKVVTKSVTVSPSKTAIKKPTKRKPPKRVKNVDVDTGPLPPVVSPSAPEASASQVEFELQFKPKKRQRGRMEIDQVTGNMTFTINLGNRYKSSQGSLLFKLVKGSDGTEWYECSDCPSTRLPVLSRKENQRGPFRKHYIDFHSKRHKCQLCPEALNNFGLHSQLVKHLASSHEIFSMNSYYKAIGMPYNLKRTLSVRKSCEICQMPYIGSRQHTYKAHLMSHMNEEEKMEALLLGGNRSTYKEIIQPTPHQLENGVVALCTECGSFITKGKQGMRRHYETSHPELVDEKDKDPTPGKGRHLCPYCGNSEYKCKFPSCSQKELGEATLKKHVQEAHGQSEEADNRLLCLDCGKVLASAWCLKQHGLVHSKETPFECHLCPKRFPLKSTLKLHLATKHLVGTEMLKCEQEGCGKLFPNLKYFRTHGRKAHGIFLKGKNKQGNETETSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGU8</accession>
    <name>A0A1D2MGU8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor-like protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14454</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001292">
        <property type="protein sequence ID" value="ODM92230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGU8"/>
    <dbReference type="STRING" id="48709.A0A1D2MGU8"/>
    <dbReference type="OMA" id="ETTFSMP"/>
    <dbReference type="OrthoDB" id="365445at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46688">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46688:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="22185" checksum="E24039A8227E2FB8" modified="2016-11-30" version="1">MACLCIGPISSGKTMLLKRLQGIEVDESTSTVETVGSNIVQIAKVSSVGNDGESKKSGSMSAKEEEKNFVGIREVGGSMSPLWPSYYSPYKPIVYVIDSSNLFQVSISTVHLMEILSHEKLIRCRVLIVLAKNDLTDTKKLNLLKFMMRLDNIINQAGKRVTLLESSSITGDGVEEIRKWIVENTAFSARLNQIEKGMVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHR5</accession>
    <name>A0A1D2MHR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">B-cell lymphoma 6 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14311</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001250">
        <property type="protein sequence ID" value="ODM92374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHR5"/>
    <dbReference type="STRING" id="48709.A0A1D2MHR5"/>
    <dbReference type="OrthoDB" id="3565419at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24381:SF393">
        <property type="entry name" value="CHROMATIN-LINKED ADAPTOR FOR MSL PROTEINS, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24381">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="691"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="720"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="748"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="776"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="804"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="274"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="854"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="897"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="862"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM92374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1067" mass="116263" checksum="396AA4BF81ED0B69" modified="2016-11-30" version="1">MEAVQIEHLAAAASAVRANGNGLSGEGDDGVASTMNGQLEIEIPTGERQGAIHTIQLQSPGGSSHIVEGLVVTTAGGGGGPGDEGETTLFHPTSAGTFILPTTSNHHHNHLAQTSTIVTSSSPSCEVITADSSDQHILSGLQVVRVTTGENGETIFLVPSSATTTDKHGDMQQVMVLQSAEEITEEVQQQEMMDETAVELNIPSPKPVLTTVKQEVNSSSVTANSEDPLRHHYQPTTTLVVVTGNNSGVGGVPVPTSQPQQQQMLSEHKPIIAAENGRSSGGGGVAANNATKTTLPTPNGSVDNRPKRKAALKATALRRELGIGVPPTSSSSSSPSKKQNTQKSPRSKSGTKIEVTHLTPPKSQTLSIVSTTSHAPQFTQNTQPQPPPPPIVISAPPPVTRVMLPGGTQIQGSPGSYFLLPEDVVSESDDDDTNTPVRKCIVCLRRRRFTEDIFDGNNATPNNAPTKQQLLQHMDVLIAHLNISAKGKPSDVGICPTCLDSLQRWHVFNCAIVKRHEAARATGAPFDDSLLNCEPFETRVYRNFRKIAKVKEVYLSATHSHLSRRHITEKDWDFFCDNLFRFNSVKSERARELEKYITCREKLSHIYCIKCQRLVKNGKKGFMKHMKTQHPHESILFPCDICGNQFPDKDMTASSEEYYPHWISHFYFNTSPQQWNAKSQVAPCSNEDRPWKCDHCDASFKMKGALVSHRDVVHFNLKNHVCNICGEAFKSASSLRGHVRRHEGRRDYKCEVCHKEYYTYSALKGHKVVHQTARDFICGICGKAFKKKKALEEHGTLHTGVKPHRCPICGREIRVKSNLYKHMKIHKKNAELGITSGRGRSNVNNSNTTVQVTSIASASSGTPTKTPTQIQQPKTENKMEFKVKQIKVEEQSMIQVKEEPHETSPIVQHHFHQQGASSSVNVNHPHPNNNSTSSPIQGATAVDVVLENELGTGDHRGPIVVSIVTDGLSGGASNILEMDPEQQAQLLSAVTSLATSQGQTVTVSAHPGVHPTTSATFLASPHPQQLQSVSATTTTTTSSQQDPILGVSNTQFYNTQQFFTSLDQLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHS4</accession>
    <name>A0A1D2MHS4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14122</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01001199">
        <property type="protein sequence ID" value="ODM92560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHS4"/>
    <dbReference type="STRING" id="48709.A0A1D2MHS4"/>
    <dbReference type="OMA" id="SHLACFM"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF6">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904059" description="alpha-1,2-Mannosidase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="287"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM92560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="461" mass="51895" checksum="1EFF250A0194BD63" modified="2016-11-30" version="1">MKVAVILLVATCVVFSMTRASPLVGKPNAKPLITQGGEDPDPIIRQRRDFVKQMMKDAWEDYVRFAWGQNELKPISQTGQNGGIFGNAEIAATAIDSLDTLYIMEMMDDYQRAKGLVTNITFTGIDAAVSIFETNIRIVGGFLTAYALTQDRVSEAVLAEFGTLHLEFMYLSDVSGDVRFREKALKIREVMKNIEKPKGLYWNFVDVNTGRFTRNHVSIGALADSYYEYLLKAAIQLDDAEARQMYDDAMDGFVNNSLVKISKPSNLLYIAESRDDRVEDVVGHLACFAGGMFALGAHVDPTNKNAVRDAEIGRNFTNTCHESYIRTATKIGPEVFRFNDEVEAEGQFDSDKAYILRPEVMESYLVLYRLTNDTKYRDWGWDAAQAIERYTKAGPGRGYSGIRNVDSTNPAKDDVQQTFFLAETLKYLYLLFSTNDLISLDQWVFNTECHPLPIKGANPNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI87</accession>
    <name>A0A1D2MI87_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative tyrosyl-DNA phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_13977</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001171">
        <property type="protein sequence ID" value="ODM92706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI87"/>
    <dbReference type="STRING" id="48709.A0A1D2MI87"/>
    <dbReference type="OMA" id="GHHHTKM"/>
    <dbReference type="OrthoDB" id="47785at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019406">
        <property type="entry name" value="APLF_PBZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10283">
        <property type="entry name" value="zf-CCHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBZ-type" evidence="13">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="102"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="523"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="11">
        <location>
            <position position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM92706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="627" mass="70550" checksum="7CA89337CBC634FC" modified="2016-11-30" version="1">MEPNWVNPDAPAKRQRLNPPTVTSPNSRNTIRGECRYGSKCYRRNEAHLVQFRHDLLEKAYGLMKAAGDFTRLPQHFNLEDGDENAILDQAIILRDAGFETPSKTNVPEAPSSSSHSNNVPPVAKTFGSSGGGDRWKGSIGNLSDERRRKYLEQKEKIQSAVVKTRESRNEDLNQPAIKPLDSKRNVRNMAQKWESSCPFNVFLTKVRDIPVEVEGVLSASFVDLFDPSLGEVKALCHINFMVEANWFFDQTIRAGLEGKPTWLIYGEESEQLKEAPKAFPWLKPFGVKSPFPFGHHHTKMSIVQYTDSSVRFMIYTANLVESDWDNRTQGIWISPKCPKLPSGSSPSVGESPTKFRTDILQYLSTYPVKASAAWKDVIKSIDCTDIKVFLIGSVPITAQSSFDGFQFGIKKMEKILRSYEMETEPNWPLIVQCSSIGTLGTSPDNWLTSEFGSALAGKDKRILGPINLVYPTEQNVKGSFDGILGGGCLPYSALTHMKQKWLRSHFCQWKADCSGRSRAPPHIKSYSRCSPDQTKLAWFLLTSANLSKAAWGKLNKNGDRLSIMSWEAGVLFIPELLCSSKYFTVASNDANNRFPLYFDIPVTRYEKKDVPWYFEMLKLAMSADSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJP2</accession>
    <name>A0A1D2MJP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001077">
        <property type="protein sequence ID" value="ODM93085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJP2"/>
    <dbReference type="STRING" id="48709.A0A1D2MJP2"/>
    <dbReference type="OMA" id="IVEGAQW"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663:SF11">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904131" evidence="1">
        <location>
            <begin position="26"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="22"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="16016" checksum="87ABBB493F56A1DE" modified="2016-11-30" version="1">MNNLTVFSLLALAVAVGSIPTEAQGQGPPQAPAQGQAQGTKNIIDVYSESVFNYAVLNNRKPVVVFFGSDNCGACKWMYPQLERLVKNRADKMYLAKVDTEKLDVLAADYGVTASPTIMTLFYGEIVEIVEGAQWSKVVALVNNASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK08</accession>
    <name>A0A1D2MK08_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metalloendopeptidase OMA1, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Overlapping with the m-AAA protease 1 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13286</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 9">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001000">
        <property type="protein sequence ID" value="ODM93396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK08"/>
    <dbReference type="STRING" id="48709.A0A1D2MK08"/>
    <dbReference type="OMA" id="NDLEWTI"/>
    <dbReference type="OrthoDB" id="7464992at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07331">
        <property type="entry name" value="M48C_Oma1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051156">
        <property type="entry name" value="Mito/Outer_Membr_Metalloprot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726:SF1">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="11">
        <location>
            <begin position="189"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM93396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="373" mass="42272" checksum="223B1EF229298B9C" modified="2016-11-30" version="1">MYSIVLKNGSYVFHATRGMKSLSRIEKIFDLPKIKCNIPATLALTRRQVQIQPRFFFQTSSRKEALPAAAVSKFGAVLLGRTVRKYWRNLPEEKKIVWKKKLKRSKYIIAGILGAVGIGMGVYYQSHVQEAPVTHRKRFIAFTNDQIMESSKEALNSVLLLANEGQIIPATPETSELYDRIVKVSQQLIKGNADLPQVNDLEWTITVVFDNKNVNAYVLSCGSIFVYTGMLYMCDSDDQLGIILGHEMAHAVLGHSAEDMSMRNFWDFLFIIPLAALWAVLPNDLTAKIANWAASEMKRIIMDLPYSRFIEEEADQVGLILAAKACFDIREAPVVWAKMRLLAEDDDTILSGSQLTLHMKNVSTNWMSWFRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKS7</accession>
    <name>A0A1D2MKS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000945">
        <property type="protein sequence ID" value="ODM93617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKS7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="481" mass="55676" checksum="E3556CB9FE46B567" modified="2016-11-30" version="1">MEAKTQNGRKVDDSLITISMLLPEIWEDVFSLLPASDFLTVINACQEWRQLLASRRTSMLLPLVLPVLKEYLPFQTLLHCRSVSKSAKCYIDEALTEYSSPLQYFQRVSCKDEWFQRNKIHQVIETMNLKYDFRDRKVLEKFLAHFTIHSYASSSSNEDANPLLTRHVALSLDLSEDPDEEVEMITACQLRRLLLPNYGAHVSVFTCEIMTGFDHFNFLRLLLLLCHLPNLKVLKVVGSLEEWMEEAEYLRVAEFPDLEQLETLDLEEFTDLHVEGALGPSLFKHYGPQLKTLICSGRLFDATTITVTKLNIYLPNLLYLRVKAVTSGALFKLSKIDWQLECLQFKDILSSDRRLNLGQILQTVNKFGKTLTHLELLVLLSSEQVNRFDPSKMNMMPKLKTLSTTLGNMNTTWFWKFIEDKCQHVRELCLHTDKMVTTNDRELAKRGFRLLPKLTRIVFWIFPVNSDSSHSLVIQRQTCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLF6</accession>
    <name>A0A1D2MLF6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Splicing factor 3B subunit 6-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000903">
        <property type="protein sequence ID" value="ODM93850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLF6"/>
    <dbReference type="STRING" id="48709.A0A1D2MLF6"/>
    <dbReference type="OMA" id="HQPDKMV"/>
    <dbReference type="OrthoDB" id="29647at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000604">
        <property type="entry name" value="Splicing factor 3B, subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="19"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13336" checksum="C10E9B99F1BFF563" modified="2016-11-30" version="1">MAMGMQRRANVRLPPEVNRVLYVRNLPYKITAEEMYDIFGKYGAIRQIRVGNTPETKGTAFVVYEDIFDAKNACDHLSGFNATKAFKKVDTDKKLEEIEKMKTKYGLGTPEQQPQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLY4</accession>
    <name>A0A1D2MLY4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000865">
        <property type="protein sequence ID" value="ODM94076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLY4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="24308" checksum="F064F982C4BCF324" modified="2016-11-30" version="1">MEVKRGSGENPSSARHERQGSDGCKIYCCSFCYRFEVPSYESWLWHLGSREHQLSINKSGASSQWRRDDIRSRCVTVYGVKGLTSREILEYLGHWGEVEDFQYFFLEEGKSGLCNYCLCLYRDLESAQACIKIGNHEFKGKKLEIVARRDVPFPRDPARDEERSKRRMNQGGMGWDYKRRRYEDNEEDMKSRKEDKKKSKRDDVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MME5</accession>
    <name>A0A1D2MME5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Differentially expressed in FDCP 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000869">
        <property type="protein sequence ID" value="ODM94031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MME5"/>
    <dbReference type="STRING" id="48709.A0A1D2MME5"/>
    <dbReference type="OMA" id="NMICPKC"/>
    <dbReference type="OrthoDB" id="1918044at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20819">
        <property type="entry name" value="C1_DEF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051366">
        <property type="entry name" value="DEF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047983">
        <property type="entry name" value="DEF8_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025258">
        <property type="entry name" value="RH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12326:SF3">
        <property type="entry name" value="DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12326">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13901">
        <property type="entry name" value="RH_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01175">
        <property type="entry name" value="DUF4206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="Multiheme cytochromes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="7">
        <location>
            <begin position="111"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="438" mass="50342" checksum="5338AED6C2018178" modified="2016-11-30" version="1">MDMNDPDQDSLLWESDDDSKSNDLSILTATTDLEENYFASPIGDSSLQTVEAVEDAVRHVKALILNTDGVSDERMKLVRRLIELRIRLEEIKETQDESGSHSSDELRMVNGHHFVLQGHLSGGGGGGLFGGMMNSTVRSYDGCNRCGGMIWSLIQSWYRCKGCFYQSHQKCLNNIIRSCPVHLISSETQYISMICPEVGLPAQKYKCEECKAHFTLKNAWMEPRKCDYNGKFYCPTCHKNLTMPIPARIFHNWDFEERKVSEATRQLLSLMLRKPNIHLEAINSKLFSFVEDLNAVKRIREEIIIMKDYFRTCREATNQKLLWRLEEKHHFVENSHMYSLQDLLDVNNGSLLPYLQKVHEDFLNHIKGNGSPNSECTTCMGKGFICEICENRHIIFPFDNAIHQCSLCHAVFHNICFAKRDSCPKCVRRTKRSSISPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNY3</accession>
    <name>A0A1D2MNY3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Medium-chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12080</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000783">
        <property type="protein sequence ID" value="ODM94602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNY3"/>
    <dbReference type="STRING" id="48709.A0A1D2MNY3"/>
    <dbReference type="OMA" id="KYDLAEH"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070991">
        <property type="term" value="F:medium-chain fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000026">
        <property type="entry name" value="Acyl-CoA dehydrogenase medium chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000011">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000007">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF2">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="39"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="153"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="8">
        <location>
            <begin position="265"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="45716" checksum="33F7F7401C62CC0F" modified="2016-11-30" version="1">MAVHRIADLSRTLLLRSARPFSTSSSLQSDIGLNFELNEVQRDLQQLARKIAREEVAPNAPKYDASMEYPWEIIKKIWHLGILNPLVPEKYGGPELGCVGACIISEEISWGCSGVLTAAFGNSLASSPVLAGGNEEQKKKYLGRLIEEPIVAAYCVTEPGAGSDVSGLKTRAEKKGDEWILNGQKMWITGAGKASWFFVLARTDPNPKTPTGKAFTGFLVDADTPGVTVGRKEINMGQRCSDTRGITFEDVRVPKENVLGTEGIGFKLAMASFDKTRPPVAAGAVGLSQRALDEATKYALERKTFGTQIINHQAVAFMLADMAIGTEVSRQIMLRAAWEIDQGRRNTYYASIAKAIAAETAAKSAADAVQIFGGNGFNTEYPVEKLMRDSKIFQIYEGTTQIQKMIISREIVGRLKSSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQG8</accession>
    <name>A0A1D2MQG8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cadherin-87A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_11608</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000716">
        <property type="protein sequence ID" value="ODM95064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MQG8"/>
    <dbReference type="OMA" id="HIRREWC"/>
    <dbReference type="OrthoDB" id="9990384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000266">
        <property type="entry name" value="Cadherin 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000098">
        <property type="entry name" value="cadherin-23 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000015">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000058">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF422">
        <property type="entry name" value="CADHERIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1742"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="51"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="171"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="282"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="399"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="513"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="629"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="730"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="834"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="955"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1056"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1161"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1299"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1391"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="15">
        <location>
            <begin position="1513"/>
            <end position="1637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM95064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1910" mass="212492" checksum="B5B4F49FD965EEFB" modified="2016-11-30" version="1">MKETKPWKWRQFAASNTLRFLVTIFIHGILITGCHANLPPYFTDDMNNHVIPENTPVGTPVYTLKGVDPEASTLRYGIMGTDKLAVDDRTGIITVAKPIDREVCEKIITFLIILYSSYTAILIVSTMDRLKVTVTLEDVVGDGKGENNIVSLPISLTISDINDNPPIWQNQSSFESLEIVEDTRVGNKILSIDVRDPDLTGMSLSVNCTASLQSPEACDYFHIEVKEATAGVLHGEMRLAKKLDYNKRSMYQFVLSASDGEHNSNVGVLIRIKDVQNTPPLFTGAMAGRVMEDSPVGTLVMVIQARDGDLGKPREVRLSLLSNPGDAFQLDGKTGHLTTTRPIDREVLGSVLMLQVKAQEIPITDEQSITSQADIDRLETYANMTVLIDDVNDYAPKFNSKEYATEISENIPIGTPLPELDMTITDEDTGTFADFTLKIDGPLSELFDIQPKFATGHVRPVIRVKKAFDYENPNERKFLLLIVAQNTDEPELFSTATVAVSIVDENDQKPLFDRDVYSIVVPESAKPGTKIGQITADDPDSNEFGKEGLVYQVVGTGYKKFRVNNHTGEIFVADCEEFKKGENCLDHETQKSYDLLYMASDMLKAEGYLRSIVPLQIIVSDSNDNAPYFENEYSRVIPEDTLVFEPRFFIMARDEDKTAVLTYKILNGSALPNFKIDENTAELLVKSERLPPGNYSFIVEASDGLFEARTKVRIAVTDINNHHPTFTEQTLSRRILTIPEDTEVGSVVLQMKAVDHDLNDNGVIRYVIDKGAYGYFEIAEETGELVLAKELDNDVVPHFDLLITAHDLGTPSMRTSTAVQINVGDVYVRLPKIAPVMQRAQVSESAEIGEVATIITTNADDLNLSVENLDLRFQFVEPVEARNLDNKVIHNFTAMHNWFQIDNEGKVIVSDALIRELVTTINFTVMVSSDKARPGVSHFGTLLLTIFEVNDFPPKVEDLEIETFEELPPGMGILTLEAEDPEGGQISGYYIEQGKEYFSVDNKTGEIKVAGRLDFEDKPIYNLTVVVADSGVPQLSSTATIMVSLLNINDNNPKFNETEYEASIPENAQEGTYVTTVFATDPDIDDVITYEIEPSDYSSAFSINRLGEIKVSKEGVGMLDREGMANPHVTLRVKANDTERSGYTSVRITILDVNDNWPRFEQKSYQITVHAPLTAMQEIIKVTANGGDLEETDDMNYKIISGNDEGIFEIDRSTGIIRASQAFEKSGEFRLVVEITDKDEINAVPDHYDQAGVLIQILPGNFRKPEFLFPNKVNSTLVALESDLAEIDKFSNGDYSKVIGQLSAFDPDEGEAGKIQFYIKNGENFVTETDYFRIETESGKIHQIRPLDREEMNKYDLVVVAKDGGVPVSTQSQHVLTIMIEDIDDHKPVFQKKHYNFSVKENSLENTFIGQVKALDQDEGKNAQIFYFLVSDETNRLLNDDFRVDIKTGMIHTNAVLDRERIENYLLYIRASPSPIISKSLETMSPEDYKDNPSVATINVTVLDENDNGPRFPEKQYYAAINSDAEPGREILTFDSVDFDSTSPVQYSLLGANLILDDFKSGGSVVPSPFRVDPNSGRLTISATAMRQYAGGNNRFQVKVGVRETIPPYHSDSTLVHVWVVEDTQETVLTLKQPPKEMVTEQLVDTLRNITGNMVLVTKITPHVTEDNTVNKEWSDVYVTAVEKKSLQTVAVSQFLQALDLGYDRLRGDETQILLHSAVPAVPTAETSGEYYFNGRETFDTAFAGLVALIALLCMGLAAILAVCCCLNKMTADSEKSSNLHGPGMKYPLNPNGSIPGTPLGIRHQQGDMIEDLATDNPLWIDHKMKTYEEQELTMQVASELDNSNGSIDDGDGLEELEDGLLTMSVVEKNMPARQQSPQFSHAYATLHPHPTDSYDNLNILGEDTVAVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQN9</accession>
    <name>A0A1D2MQN9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative tubulin polyglutamylase TTLL2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11599</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000715">
        <property type="protein sequence ID" value="ODM95085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQN9"/>
    <dbReference type="STRING" id="48709.A0A1D2MQN9"/>
    <dbReference type="OrthoDB" id="277439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF118">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="608"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="608"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="631"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="837" mass="96515" checksum="3CD0ED9714ACA70D" modified="2016-11-30" version="1">MPENNAEVEWAGESGTLHDENYLSTGKQFHKSTKNAPVIYCTSFKNKYFATSRYRESIVELRKRAAREKALDDITLLNAVKANYRFVYRINDGIGTTNTILQKVCEERGWREFQERQSGTPYEKAMKGATGWNLWWSYNLYQFSPYKYLRHWQFTNHNPKGFQFCNKLYLTHYLRKMKSIHGPIFDFYPTSFIVPEDYLRLNMEQNKRSESCSLYTFHNLLTCTKDEETQDSSLKMNTEKLRKRVKTPLSSHDHKGTSNSKAVAFEQRCSPVWISKPIGQSQGKGIFLTTDLSNIATDKKSVIQEYISRPLLIGGYKWDIRLYVCVSAIDPLVIYIYQEGLCRFATEKYDTSDLTAMYSHLTNASLNKLSPTYEEDKELIGQGCKWPLRKLRQYFKDQNIPDWYMWQNIMAMIVLTVIGDSLRLGYSASNRNCFDLFGFDILVDEELRPWLLECNYSPGLGGDCETDEIVKKPMLHDLFDLLGFPDRSSYTKSEDTSAEADNRGGGDAALSGEEVLNSDNAYAIDATRQYVDMLLQRIANADAIEKKRSEKYKPEYCYSTAARLKDAKSIYSQNLVVQYLRNQTNGKMCKQVKDLILAQAAKRFKKTNTNLENQKSNSPTRCTSKEATTTRVKDKESSETTVKEDSLSLDHQEQKVAPKSTNNYCSKKQAEFPHPSSEAFQKLKHYFDAGVDYPVDTKTGKFTGCPALITVKKNWFDPPKQQGQWIRVYPFDARTTKSPYKSSLTDIRQAVRSIETFMKVAEHLFMTNPNETDDYYRRKVKAICRRETEIWTPPPVCTINSSKSESTDLENNNMDEEEEDIRTILASNAIHVADTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQY8</accession>
    <name>A0A1D2MQY8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ecto-NOX disulfide-thiol exchanger 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000657">
        <property type="protein sequence ID" value="ODM95530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQY8"/>
    <dbReference type="OrthoDB" id="10039782at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007624">
        <property type="term" value="P:ultradian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12228">
        <property type="entry name" value="RRM_ENOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038876">
        <property type="entry name" value="ENOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056611">
        <property type="entry name" value="ENOX1/2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034140">
        <property type="entry name" value="ENOX_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16001">
        <property type="entry name" value="ECTO-NOX DISULFIDE-THIOL EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16001:SF4">
        <property type="entry name" value="ECTO-NOX DISULFIDE-THIOL EXCHANGER 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23267">
        <property type="entry name" value="ENOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="291"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="220"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="656"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="762"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="811"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="603"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="656"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="763"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="815"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="910" mass="99438" checksum="32731ABC2AC54A25" modified="2016-11-30" version="1" fragment="single">HPHHHHPHHHHHHAGVAIGPLPNPCIGMVAAPTAAGPVLAGIGVPIMTAAAPLVGPPPPIPPPPHNHNHQHQQQQQHSHKKLVMSPDSSDDKDKCGGHPFIQARTSPSGIASSSVSCASAMGAGSQLTWSSAPGPTGPIIQAGIAYPVMSIPPGALTEPNGAATAGMIYGVPMSAGPGITDHQVSAAAAGVNVNSVMIPTSNGIVTGSTMGMVQQAPSISISPVIPNPNQNNCTGSTTISPSQQQHQQQQQTQQNPQQPTKEIIHCKSCTLFPPNPNAPPPTTRDKPPGCRTVFVGGLPENVTEDIVREIFDRCGEITTIRMSKKNFCHIRFEMEQFVELALYLSGYRIRIGSNSDSANIGRLHVDYAQARDDLYEWECRQRQLLREQRHRERLEQERLQPPSPPPTVHYSDHEATNVAERIKGDDTFMKAIQTLFTWLEKGECLKRNSNTFYSMIQSTNSQIRRLLNEKSQYEDEFQRAKDLMRQRMTGMLMQFTQIEKIFSAACQRKVWDHFSKAQRKNIEVWRKQAAEIKNVLLEEALNERADEEMEFSDLESESGQSNKENGEPRAKKMRLTVEENAKTVHQLKVFSFLQLDFTHFSPFSLYQEENDALRCQLEASKNEVDLIKADLRSELEMKDQQLRSLQQQVLDVQSGISSPSQVVTTCPSFSDSMSPGTTTTKQNLHSPVSVSSSSPAFGLSPTHNNNGNSHPIGNGSSSSSISINGSNGAELMASSLNGCNKEIQGYCDSSSSTNSLLHLQKTQSAQNNQHNHNNNSNKHTGSNNSSNSSGGAGDDSHEILIGAVVAENAGGGGSSISNNHNKSNSNSSSDQIIGISEKEARLVGIISTFLHVHPFGASVDYIWSYAQKVLPMVRPNQIELLMTKFPSLFRQEVSGIGATFERKWVFVGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRQ2</accession>
    <name>A0A1D2MRQ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000629">
        <property type="protein sequence ID" value="ODM95723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRQ2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRQ2"/>
    <dbReference type="OMA" id="YATFETH"/>
    <dbReference type="OrthoDB" id="4737882at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050688">
        <property type="entry name" value="Zinc_finger/UBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24403:SF67">
        <property type="entry name" value="FI01116P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24403">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="472" mass="53898" checksum="52D66D3AD21A0835" modified="2016-11-30" version="1">MMNLAASSHKTDGGTARLDEVRKLPQFVKEQFRYVCSVCDHMTSDDGLLQTHIKVIHSEVNSYRCPHCQKNEETKDNPEYIVPLDKIAHHLRLHGPKLYKCGHCMMVQHQVRAMEKHIPEKHPEKKPIHYLIRDVDPDGIPSSRPSTSGAHRRHSADDPKGIIAEKWKCFLCSSKSVFGAWEEIKAHCESVHKVNSQFMCLVCDFSSDDVSEMLTHCQEKCKSVEKNKILVMFSKCETFDDDSASTLPMWKKHGGAVRHIHGNFTEDSVALIRQYNNQQTSDTNSLTNSPLRGSMSALPAKAVAKPTSATSKARRSTTCPAPPKINLAKTILTMPIPSSPPKVEAFKYHCHKCDMYKTKNPNELRIHLFNEFRYKRWKCLICNATSTTEKSLKGHIERDHQKVYQPDLYYLQPPNPDIEAEIDDCIERQNRKKELINSFAIEKFGKLCCKHCKEEGLTYATFETHILQKHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT10</accession>
    <name>A0A1D2MT10_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000557">
        <property type="protein sequence ID" value="ODM96269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT10"/>
    <dbReference type="STRING" id="48709.A0A1D2MT10"/>
    <dbReference type="OMA" id="CESNCEF"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098855">
        <property type="term" value="C:HCN channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003254">
        <property type="term" value="P:regulation of membrane depolarization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051413">
        <property type="entry name" value="K/Na_HCN_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689:SF14">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="430"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="607" mass="71060" checksum="FB83D0F7C8EE9316" modified="2016-11-30" version="1">MYSTPLAPSREVLTALDEPDIEIEYPLLTETHPPGGIPMQCENELLLPYKWYKKLRCWFLVSDNWVVQSGIVRGYLGLYHERFLHLLSFPYVIHPFSNFYCVWVSVICFLLTISLIIEPYLISFQWYDFVKNKNKAYSLTMSVLLLMDMALTFIVGRADPNTMRVILDPIVVRRKYMSCKFWFDLVTRFPYDSIILASLSDADEMVKTKLATVRLVAFFVKLFRFQKVYSFLYRCATAFHFSAWGTQMLIHGFLVAFCVHWGACLHWLLPDVFNAGLAKPQEMSWVTKHNLWKTEYHIQYINSFLRSLGNLLTLDGGDFTPRLPEEMFCTALLIVVAQSIFAFFVSTFSSMIIEFQKEDDRYLEMLACVEEYLRFRRIPEWLRQRVLTYYDKKYKGHSYSEKQILDTMSTNIRLDVLAHSNTVLIDSCYLFADAPLNVRLSLVQCLTYDICVPGDVMMSSDTNTFNMYFIHEGRFRVFTKFGGCVKMLSTGDFFGETALLCPTTPRLMTTVVAITFAEVYKLSKKAYTKCMLQFPGVHEIIADAAMKKINKELLKFDREIERAEHILQWKEFLKQRRSQKVEEFYRDADANRVPSYYRALQFVYDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUC4</accession>
    <name>A0A1D2MUC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kynurenine formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000535">
        <property type="protein sequence ID" value="ODM96498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUC4"/>
    <dbReference type="OrthoDB" id="433474at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="97" mass="11135" checksum="7604E05ACB62764E" modified="2016-11-30" version="1">MTSEEAESWSPLLQPTLDSKDFGKNLQILIWVGAIDSPEFQRQSKEYAEKLRPKFKNVELQIFDEDDHFTIVERLCETSESSPGDCLKTALESKIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUN5</accession>
    <name>A0A1D2MUN5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dynein heavy chain 17, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUN5"/>
    <dbReference type="STRING" id="48709.A0A1D2MUN5"/>
    <dbReference type="OMA" id="KNGSNWG"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="2">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="112" mass="13208" checksum="7C0B3F7399F9AF15" modified="2016-11-30" version="1">MVDHRADFSKWFQQEFKFVKFPQGGSVFDFYIDNETKRLVPWSEKVPKFELDPDIPLQATIVHTSETIRIKYFVDMLMEKGQPTMLVGNSRKWKNGSNWGQTRVSPRNSHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWP8</accession>
    <name>A0A1D2MWP8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine proteinase stubble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09314</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000450">
        <property type="protein sequence ID" value="ODM97361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWP8"/>
    <dbReference type="STRING" id="48709.A0A1D2MWP8"/>
    <dbReference type="OMA" id="SESWAIT"/>
    <dbReference type="OrthoDB" id="93664at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000054">
        <property type="entry name" value="Complement C1r subcomponent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="121"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="32"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="363" mass="40103" checksum="ED40D666EC251149" modified="2016-11-30" version="1">MTANGTHLGVCRDRFYIGSCCKLPELDGGNENGYESNEIDDTNANPKPTSSPKPSSTTTTTLASTTVDPFTTASTPVTTTRPQVLDRTQYPDAAFFTPNGTLLINDPKLICGRRFFPASRIVGGADATYGKWPWQISIRTWQNQAKTYVHSCGAALLNENWAITAAHCVEKVLSSEVILRLGEFDLSDDGYPFNFTERRVQLIITHPNFSGAKRSFEHDVALLRFYEPVTFQPNIVPICIPEGEEDFVGKTGWVTGWGRTYEGGPIPTRLNEVQVPIMTNPDCEKMFLDAGYHESIPGIFLCAGWPQGGKDSCEGDSGGPLVVQHGTDNHFVLAGVISIFGNRLCPDWPPWRLYKNHRVPKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0B4</accession>
    <name>A0A1D2N0B4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Troponin C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000337">
        <property type="protein sequence ID" value="ODM98641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0B4"/>
    <dbReference type="OMA" id="IFNNHER"/>
    <dbReference type="OrthoDB" id="10385914at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="12090" checksum="F82109057D829328" modified="2016-11-30" version="1">MEFKVRKESQTLMEKTFNTYERRGCVRTYQLGSMLKAMRPDLNIEQTQLEAIAAEFDTSREGKFDLDTFNKIAIRFLVKQARRESDSFIHKHEIYLSDFADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0N1</accession>
    <name>A0A1D2N0N1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Zinc transporter 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_07904</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway. By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Zn(2+)(in) = Zn(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29351"/>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000322">
        <property type="protein sequence ID" value="ODM98790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0N1"/>
    <dbReference type="STRING" id="48709.A0A1D2N0N1"/>
    <dbReference type="OMA" id="KWRANER"/>
    <dbReference type="OrthoDB" id="78669at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904257">
        <property type="term" value="P:zinc ion import into Golgi lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="15">
        <location>
            <begin position="41"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="170"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM98790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="381" mass="42284" checksum="F0B753D2CA4511A2" modified="2016-11-30" version="1">MMLPLTKKDCDDKPYKSKSRVLEKLAGWVRLIISDRDSRNLFCFLILNLCFAFVELFYGIWTNSLGLISDSFHMFFDCTGLVAGLIASVIAKWRATDHFTYGFVRAEVLAGFLNGLFLLFIAFFILSEAVERLLEPPEVKHERLFLVSVLGLLVNLVGIYVFQHGGAHGHSHGGGGHGHSHGGGHSHDSHKHDDHNPSFLSHGHSHDHDAGHGHSHNGASHFHSHGGESGGTGANKQIMRGVFLHILADTLGSVGVIISAGLMWAFEWYIADPICSICIALLICLSVLDLIKESAFILMQRVPYSIDNQLPQCYQRLMQLEGVLSVQEPHFWTLCSDVYVGTVKLEVSRNADPRYITQNAQLIFQGIGVKKMTIQLDFLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1A3</accession>
    <name>A0A1D2N1A3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000300">
        <property type="protein sequence ID" value="ODM99087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1A3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904853" evidence="1">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="68" mass="7463" checksum="280C2EF6C0D68902" modified="2016-11-30" version="1">MLKSLSTAKIILLVVPVFLFLALLASGTAADNGSLSSTTRRPTPAFLREETLQPLPNHVSNTLRIFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1C6</accession>
    <name>A0A1D2N1C6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low-density lipoprotein receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000317">
        <property type="protein sequence ID" value="ODM98844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1C6"/>
    <dbReference type="STRING" id="48709.A0A1D2N1C6"/>
    <dbReference type="OrthoDB" id="664115at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="16827" checksum="F89E3C97ACE4B702" modified="2016-11-30" version="1">MGWGKPYKPPQLPSRANDELEANRPPAELSNEVQRIIPAESGYNKQQTNEHYARSGLSGPDAGTVAGIVIGVLSALLVLVIIVVLLLYRQIFLKHENSMNFDNPVYRKTTTEDHGGHISIEKTRGYHKTYPATISEEAQEPLTNNVGANEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N290</accession>
    <name>A0A1D2N290_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Pinopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_07673</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000304">
        <property type="protein sequence ID" value="ODM99015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N290"/>
    <dbReference type="STRING" id="48709.A0A1D2N290"/>
    <dbReference type="OMA" id="CFENVKL"/>
    <dbReference type="OrthoDB" id="2101615at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="8 10" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM99015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="19824" checksum="DDF6AD72CA5C7252" modified="2016-11-30" version="1">MTLRTPMNMFLVNLSTADFITAFFGSPFPFLASIYGYWPFGETMCIIYAFGMSVGGITSITTMMVLAFERYLMIARPFRAADLRLQHSLGIVSLIWFYSLTITLPPLFGWASYGPEGPYISCSVSWERDDLTTKSYICFLFVLGLVLPLFTIIFSYAGIVSTIKSYRVKNAAPVAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2H9</accession>
    <name>A0A1D2N2H9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000275">
        <property type="protein sequence ID" value="ODM99497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2H9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="139" mass="15762" checksum="BFF0F7DBA96B38FE" modified="2016-11-30" version="1">MHNSLNKVLTELCEINAVFLIRDQKIENVAVTTTRKQNIPNQANSRSGEASDEQDHQSECSHACAYDHKCQLNWLQPLHLEMEDIREHQPCESDSPIHCAAKDSHSSKAHDGRYQGSVRNSDIRQLGDRCRIRVTVADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3S2</accession>
    <name>A0A1D2N3S2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Venom carboxylesterase-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06760</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000247">
        <property type="protein sequence ID" value="ODM99919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3S2"/>
    <dbReference type="STRING" id="48709.A0A1D2N3S2"/>
    <dbReference type="OMA" id="PIKEHEK"/>
    <dbReference type="OrthoDB" id="8174896at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904994" evidence="5">
        <location>
            <begin position="18"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="20"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="563" mass="63001" checksum="96357C81D15CF9E5" modified="2016-11-30" version="1">MKLVWTLAILCCSAAIAEDAPKVTVSEGQIQGLTYRSRKGNKYYGFLGVPYGKAPVRFGTPQPADNWDGVKLATKFAPHCFQFCLVSQRLDGVEDCLTMNLYTPKLDGNLPVMVLLHGGGFQFGSGSLSEAKYLMDEDVVLVTIQYRLGALGFLNTEDDVVQGNMGLKDQSYAYNGSKELKKCGGDPSRVTIFGFSAGGASVHYQMLSPMSKGLFSAAISESGTALNPWAFQSKPKQLALRLAENVGCVRDTSEALVECLRSKTPAEIVTGQMKLSKFPHEFDLISMLFCPSVEKGESEPKFISDSPYNLLVDGKLASDNVPWIAGLTRDEGAFYTAGILESEKSMQKLNSDWYKMLPNILYYENSASPATQRRISKKVWEFYFGDDSKITTDKYLKLGRVLGDRFFLTGISRAIREHAKKYESPVYPYIFSHDSEDSIVRGFLHAKRSYGVAHADELKYLFNKTYGAPEYELNTDEGKFSEQLIKLLVSFARDGKPTSAWGSAKSWEPLSLSKDDETITWYEIDTDPKVTTKDPFKERTDFWESLPLKEMEKEDYPDEKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Y6</accession>
    <name>A0A1D2N3Y6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_06687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000240">
        <property type="protein sequence ID" value="ODM99997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Y6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="31911" checksum="16B873CE66FF96C1" modified="2016-11-30" version="1">MGKVNKIATFTIYLLLGLSIIATTATKKRRKNTSSLVDLLSPPNEVHKKQDPAQQCCDSYCCSFCEETTTTEPTTRTTTADPPTTEYSCPDQYRCDDCYPHTEPPYCPDQGRCQECWPDTTPYPVTCPEHTCPSITCPTTTDCICTTSDPCPTPSQEPCPSCPTTPPPTTAVPTGGTTCPPSRFANPQFTKTIYQSSLPTWPLAGTTVHLGIHANTTDGSPLRYQLVTTFEFLTLSASQDIIFTSNVGDGAFVGPNNVMVIEVSALVIGDEDRASNAAVVLVFPRSTKELTGDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N511</accession>
    <name>A0A1D2N511_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000215">
        <property type="protein sequence ID" value="ODN00311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N511"/>
    <dbReference type="STRING" id="48709.A0A1D2N511"/>
    <dbReference type="OMA" id="MLAQASI"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF814">
        <property type="entry name" value="MEPRIN A SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811363" description="Metalloendopeptidase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="70"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="29338" checksum="3878168A6E355E7C" modified="2016-11-30" version="1">MKTIMLAQASISVLLIVISQTSSLPSPGLPKLPLPQRSRIDTRILESMINPNGTKLECTMTVEDEFKGRSGLIPIRYRWQNFNVFIDPAYNSNERGLINNAMYRLSQVLPCVRFGIWQEGSRPSGDYVHIKKASGCSAAVGKQGGAQHMSLASPGCMSMGTMMHEMIHSLGFYHEQSRPDRDDFVIVRYQNIQPGTEHNFNKYSSSQVSTFGVAYDLRSIMHYGSTAFSKNGQPTIIARNGGAVGSTGDLRNSDIMKLKRMYNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N542</accession>
    <name>A0A1D2N542_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Troponin C, isoform 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the troponin C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000210">
        <property type="protein sequence ID" value="ODN00388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N542"/>
    <dbReference type="STRING" id="48709.A0A1D2N542"/>
    <dbReference type="OMA" id="HELDIMI"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000103">
        <property type="entry name" value="Troponin C Ib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="13572" checksum="2E6C3CF6A6F771C2" modified="2016-11-30" version="1">MVGTILRVMGQAFNEQTLRELIAEVDQDGSGQIEFAEFVILASKFIVEEDEEALQKELKEAFRLYDKEGNGYIPTSCLKEILHELDDQLTNDDLEGIINEIDEDGSGTVDFNEFMEMMTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N630</accession>
    <name>A0A1D2N630_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06243</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000207">
        <property type="protein sequence ID" value="ODN00416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N630"/>
    <dbReference type="STRING" id="48709.A0A1D2N630"/>
    <dbReference type="OMA" id="EVNCREM"/>
    <dbReference type="OrthoDB" id="10258888at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="174" mass="19055" checksum="FE7479210301FF80" modified="2016-11-30" version="1">MDTLHCAASRGHTDCLETLIALCGAEVDIIDNNGCTALFYAVTLGNADCTELLLNYGSEPNRQDRKGRTPGHCGAAKGQLETLKLLAKHGANLWLRNVRGDLPLHEAVLSRRKDLVLWLLAQRPDAVNASNNDGRCPIHLAALNNNVEMVKLSLASELMTKRNALLEEVNCREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7Z9</accession>
    <name>A0A1D2N7Z9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tryptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05304</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000155">
        <property type="protein sequence ID" value="ODN01389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7Z9"/>
    <dbReference type="STRING" id="48709.A0A1D2N7Z9"/>
    <dbReference type="OrthoDB" id="7468414at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="170"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="47241" checksum="DCFB7253BC4775C6" modified="2016-11-30" version="1">MRGNGIRIKDSLWVDAAYSDDDEEGELHFDALDQPDEAECMTLDARTWHLRNFAKNVIAILFSDNGELRTQLSTRLQPKCGCLCVSECCDDGLHGLMSLPIIGDVEPQPEQPQSPCRHRKSSHSLNLLIPEEPEPQPEAAFTEDLMKPSEPTEACPAVSLYNTWPSFDTYPFLQFIHCARLDRLCSGSLIDNRHVLTAAHCLHRFNSRDVARMQVRIGFTKSRLNDTFNDYYLERKASKIIFHKRFHEQSKMDNNIALVQLDQPVEFDEHVAPIGIFSGARGFDTGNCSGVEAGWIKYGNRKVTGISGGVIHYIEPPTSDFVLREAINRIYTNEECQSQLFTEITEDMLCAKTDIFEAHGVSASKFKGNDGGPLVIRVGDRVQQVGIKSWAYEGNQYPTIYTRVENYVDWIRNNLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8E9</accession>
    <name>A0A1D2N8E9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05144</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000147">
        <property type="protein sequence ID" value="ODN01550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8E9"/>
    <dbReference type="STRING" id="48709.A0A1D2N8E9"/>
    <dbReference type="OMA" id="NEMPSIC"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000007">
        <property type="entry name" value="Mitochondrial pyruvate dehydrogenase kinase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="233"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="411" mass="46802" checksum="F3F501C28B04EF01" modified="2016-11-30" version="1">MRLTARVYRSLGKMLDFYSQFNPSPLSIKQFIDFGRQASEEKSFQFLKKELPVRLANIMKEINLLPERLQNMPSVHLVENWYAMSFGDILEFENKPPDPETLKLFVEILTKIRNRHSDVVPTMAQGIKELKDSHHVDSSMEHSIQYFLDRFYMSRISIRMLINQHTLLFGKMPCPSRHVGSIDPYCNVVSVLNDAFENARFLCDQYYLVSPDLVVKEHNGVNTGNPIEIVYVPSHLYHMVFELFKNAMRAVVEHHGSAATDYPPIEALVSLGKEDITIKISDRGGGIPRRNTDLLFQYMYSTAPQPPASTDHTNTVPLAGYGYGLPLSRLYARYFQGDLMVTSFDGYGTDAIIFLKALSNEANELLPIFNKTSTRFYTSSIPTADWSGNGISRSMNSAHPMSMNYRLPAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAX7</accession>
    <name>A0A1D2NAX7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily. Sigma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000113">
        <property type="protein sequence ID" value="ODN02408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAX7"/>
    <dbReference type="STRING" id="48709.A0A1D2NAX7"/>
    <dbReference type="OMA" id="MPNYKLS"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000030">
        <property type="entry name" value="Glutathione S-transferase S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="86"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="24196" checksum="990D2C0A61CAB34D" modified="2016-11-30" version="1">MSAPKYKLSYFDGMWIAEPARYLLSYVKEDFEDVRFNQEQWDAMDKKDFPYGKVPVLEDTENGLKLGQSLAIVRYLAKKFKLVGETDAEAAKCDEYADVFKDLLQEIYPLWSADEEKKVEIKAAFMEKAVPRYFSVIESDLKNSKGDYLIGKSLTWADIISAHFTELFQIFLTIDVLANYPTMKAHQQRVFKLDGIREWRAKRPATPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBA7</accession>
    <name>A0A1D2NBA7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000107">
        <property type="protein sequence ID" value="ODN02540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBA7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="33" mass="3724" checksum="CABF72D9108B6848" modified="2016-11-30" version="1">MQAMQVSVVGKVQEMTTMKVERRTKRNAASSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBE6</accession>
    <name>A0A1D2NBE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transcription factor LBX1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_04277</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000113">
        <property type="protein sequence ID" value="ODN02395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBE6"/>
    <dbReference type="STRING" id="48709.A0A1D2NBE6"/>
    <dbReference type="OMA" id="WIKCWAV"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990837">
        <property type="term" value="F:sequence-specific double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000098">
        <property type="entry name" value="Transcription factor LBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000047">
        <property type="entry name" value="HTH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051892">
        <property type="entry name" value="LBX_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24336:SF8">
        <property type="entry name" value="LADYBIRD EARLY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24336">
        <property type="entry name" value="TRANSCRIPTION FACTOR LBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00031">
        <property type="entry name" value="HTHREPRESSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="6">
        <location>
            <begin position="28"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN02395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="18039" checksum="7DB29BE7CC724924" modified="2016-11-30" version="1">MFLVITDKSGGSGNTLQIFNPRQPPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDDIAQQLGLTNAQVITWFQNRRAKLKRDMEELKKDVESAKLLSAHKSFLESAHDLGLLKKRTPSQMDMSPAAAAYHISSPTSSSQSSHSPINLTSESPPSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC11</accession>
    <name>A0A1D2NC11_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03933</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC11"/>
    <dbReference type="STRING" id="48709.A0A1D2NC11"/>
    <dbReference type="OMA" id="GMFQKEV"/>
    <dbReference type="OrthoDB" id="10646563at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000081">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="10">
        <location>
            <begin position="39"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN02779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="344" mass="38174" checksum="F3166783E7523AFB" modified="2016-11-30" version="1">MGKVSAKKPKGVQDKACFKQSMRLEHAKFGQHLLKNPLIVDGMVDRAALRSSDTVGPGTGNLTIKLLPKAKKVIAYEVDQRMVAEVIKRARNAGMERKLEVIVGDICKSGDLPPFDICVANIPYQISSPLVFKLLLHRPAFRCAILMVQREFAQRLVAQPGDKLYCRLSINTQLLSKVEHLIKVGKNNFRPPPKVDSSVIRIEPRVPPPPLNFGEWDALTRIAFSRKNKTLLANFKTAAVIASLARNYAATNPNLIQSSVSATPSQNQQAGHIPIVLINPPSSSNNEIAQGGCLDFRQLEKLVLDKVEKVLTGMKFNDKRARSLDVDDFIKLLVEFNKEGIHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCW5</accession>
    <name>A0A1D2NCW5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03578</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000087">
        <property type="protein sequence ID" value="ODN03098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCW5"/>
    <dbReference type="STRING" id="48709.A0A1D2NCW5"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="29224" checksum="7A3829CCC9855DDF" modified="2016-11-30" version="1">MDRAGDPGWLRVYLNIPTVTRIFITATILVTLASHFELVSPYDLYLNPALILERHQYWRILTSFLFAGPITFGTVFNLLFMYRYSRILEEHYVQRTSEYCVMVIFLTTVVFILSARFTDMIFLNNSFTHAILYIWCRRNPMTRVAILGLFTFHAHFVPFVLLGLTILTGGPLSSDVVSIAAGHTYYFLEDVFPRQRGGFRILKIPQFLRTLFEAEPMYSEPGPNENIEEQDPNNNLIDGRLAPDVGPLLEENGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND40</accession>
    <name>A0A1D2ND40_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Dihydropyrimidine dehydrogenase [NADP(+)]</fullName>
            <shortName evidence="18">DHPDHase</shortName>
            <shortName evidence="18">DPD</shortName>
            <ecNumber evidence="18">1.3.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Dihydrothymine dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Dihydrouracil dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_03518</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>5,6-dihydrouracil + NADP(+) = uracil + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18093"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15901"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="18">Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 18">Amino-acid biosynthesis; beta-alanine biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the dihydropyrimidine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.2" evidence="18"/>
    <dbReference type="EMBL" id="LJIJ01000085">
        <property type="protein sequence ID" value="ODN03162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND40"/>
    <dbReference type="STRING" id="48709.A0A1D2ND40"/>
    <dbReference type="OMA" id="SIHCQLQ"/>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="UniPathway" id="UPA00131"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017113">
        <property type="term" value="F:dihydropyrimidine dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002058">
        <property type="term" value="F:uracil binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019483">
        <property type="term" value="P:beta-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006212">
        <property type="term" value="P:uracil catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02940">
        <property type="entry name" value="DHPD_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000007">
        <property type="entry name" value="Dihydropyrimidine dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000027">
        <property type="entry name" value="Dihydropyrimidine dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000023">
        <property type="entry name" value="Dihydropyrimidine dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000061">
        <property type="entry name" value="Dihydropyrimidine dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073">
        <property type="entry name" value="DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073:SF2">
        <property type="entry name" value="DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14697">
        <property type="entry name" value="Fer4_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 18" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 18" id="KW-0274">FAD</keyword>
    <keyword evidence="7 18" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 18" id="KW-0288">FMN</keyword>
    <keyword evidence="15 18" id="KW-0408">Iron</keyword>
    <keyword evidence="16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 18" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="19">
        <location>
            <begin position="930"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="19">
        <location>
            <begin position="964"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00052371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU364041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN03162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1008" mass="109825" checksum="0A6E8DD3D8547270" modified="2016-11-30" version="1" fragment="single">SILALNPKIKTHANLVPSAETKENKKKWKRNGDKKCGSCPPLYNNFDDVKHTTLSERGALREANRCLKCADAPCQKSCPTQLDVKSFIGQIATKNYYGAAKAIFSDNPLGLTCGMICPTSDLCVGSCNLYAAEEGPINIGGLQHFATDIFMKMNIPQIRPPCSEPGLENVFKTSKVALLGCGPASVSCGTFLARLGYENIVIYEKQEYIGGLSTSEIPQYRLPIDVVHFEIDMMKDLGVQVENGRELSTKDVTLNGLKNEGYDAVFVGIGLPDPKKSGPFKSLTEDMGFYTSKDFLPKVSIASKPGMCKCSTQKALPQLSGNVIVLGAGDTAFDCATSALRCGANRVFVVFRKGFTNIRAVPEEMDLAKDEKCEFLPFLSPKEVCIKNNKISGMEFFRTEQDETGEWIEDQDQTCRLKANYIISAFGSGLHDSEVKEALEPLVFNKYGLPKVNEKTMETSEDWVFIGGDIAGVAETTVEAVNDGKTAAWSIHKYLQGKQGFKVAPTPQLPRFYTPIDLVDISVEVCGMKFPNPFGLASATPCTSSPMIRRAFEAGWGFAVTKTFSLDKDLVTNVSPRIIRGTTSGHVFGPGQGAFLNIELISEKTAAYWCQSVTELKADFPDKIVIASIMCTYNMKDWTELAQMAEKSGADALELNLSCPHGMGERGMGLACGQDPDLVRNICRWVRAAVKIPFFAKLTPNVTNIVEIAKAAYEGKADGVTATNTLSGLMGLRADGTPWPGVGDEKRTTYGGVSGNAIRPVALRAVSAISRELPGYPVLATGGIDSAESALQFIHCGAPVVQICSAVQNQDFTVIEDYITGLKALLYLQSLGLKGWEGQSPPTPRHQKGKAVTVDAVMDKKLPSFGNYLKEREHIISEEKRRVTIEDLENKLTSREVSQPISTIPTIQDAVGKSLSMIGTYNQLNNRKQVVAVIDEEMCINCGKCYMTCNDSGYQAIEFDAETHLPHVSTDCTGCTLCLSVCPIVDCIQMIPRQTEYIPKRGIVTITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDA0</accession>
    <name>A0A1D2NDA0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000082">
        <property type="protein sequence ID" value="ODN03222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDA0"/>
    <dbReference type="OrthoDB" id="285729at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="47" mass="5680" checksum="6988AC26E6E270B2" modified="2016-11-30" version="1" fragment="single">MDKHGENFEAMAKDHTNYYQETAAQLRKQIERLKNIPQQWVAYLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDD6</accession>
    <name>A0A1D2NDD6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDD6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="73" mass="8289" checksum="7AF3E630A26895AE" modified="2016-11-30" version="1">MLNYCLEFDMTHTPTKFGKPKKIPQEVNEISPPPPSFLLLRWSQAQEGHTSRVLSSSPKRLVNSLHIFVGTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDE4</accession>
    <name>A0A1D2NDE4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex I-49kD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NADH-ubiquinone oxidoreductase 49 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDE4"/>
    <dbReference type="STRING" id="48709.A0A1D2NDE4"/>
    <dbReference type="OMA" id="TRMDYLT"/>
    <dbReference type="OrthoDB" id="1009at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.645.10:FF:000005">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="8">
        <location>
            <begin position="201"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="471" mass="53228" checksum="10824943AC5638F5" modified="2016-11-30" version="1">MASVLGINLCRKSSVLAGSVWKSAAVLSNAPTLFSNQKRGAARWYPDEEFLKTFEGPVMWSPDHERWKDLILLHEKGGPPIEKKVKNLILNFGPQHPAAHGVLRLVLELEGETVVRADPHIGLLHRGTEKLIEYKTYTQALPYFDRLDYVSMMCNEQCYSLAVEKLLNIDIPLRAKYIRVLFAEITRILNHIMAVGTHALDIGALTPFFWLFEEREKMMEFYERVSGARMHAAYVRPGGVNQDMPLGLMDDIYEFSAKFAERLDEVEDVLTTNRIWMQRTIDIGIVTAEEALNFGMSGVMLRGSGIKWDLRKTQPYDAYHLVDFDVPIGAKGDCYDRYLIRVEEMRQSLRIIEQCLNQMPEGDIKTDDAKISPPSRAEMKTSMEAIIHHFKLFSQGYTVPPGVTYTAIEAPKGEFGVYLVSDGSSKPYRCKIKAPGFAHLAALEKLGPKHMLADIVAIIGTLDVVFGEIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDK9</accession>
    <name>A0A1D2NDK9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-binding cassette sub-family F member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03341</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000077">
        <property type="protein sequence ID" value="ODN03331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDK9"/>
    <dbReference type="STRING" id="48709.A0A1D2NDK9"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000471">
        <property type="entry name" value="ATP-binding cassette, sub-family F (GCN20), member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000355">
        <property type="entry name" value="ribo_prot_ABC_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="488"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="817"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="744"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="564"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1045" mass="116520" checksum="7104CD43D6798A98" modified="2016-11-30" version="1">MPKKTKVQDDDMEGSVTSEQSSVPDKKGGKGNKKGKSKPQDDIEDSVTTSEVPDKKGGKGNKKGKVQDDDMEGSVTSEQISVPDKKGGKNKKGKGKGKHDDSDDEMEVTVTSEQSSVPDKKGGKSKKGKGKGKHDDSDDEPAPPPPKVTESKGKNKKKGKTARDDDSEEESKPAVIPPANDEDEEDKPKGPAPAKKLTAKQKKKQKKEMEFEEHLDELSTIKNDEDEDDDDGFEIAPIKPKGMQKKGFGVLDDGESSDEESASVTEPAKTNKVSKVSDDDDEDDEEEDEPKPKAKVDKKAKKKGKGKGAKDLDSEEEDLDEPSEEPVNEVDDLADEIEAISISSSKPKEDLSKPEEKKPEPELKPVPVVPVKEKEIKAKGKKGKRGKPKKENSAEPEELDQPEPDKEDVEEPEASADTEEADKDDAAPTKEVEKKLTHKEKKKLKRETEQAKLIETMLKKGGQGHSELAENFTVSQVEKHVDDGAVDIKIEKFNISAKGKDLFVNADLLIANGRHYGLVGPNGHGKTTLLRHIATGAFKIPAGIDVLYCEQEVPPEDISCVEVVLKADVKRTALLKECKELEEKTNVETDAKKQKEQLDRLNEVYEELKAINADAAEPKARRILAGLGFTKLMMNRPSKNLSGGWRMRVSLARALYIEPTLLMLDEPTNHLDLNAVIWLDNYLQGWKKTLLIVSHDQGFLDNVCTDIVHLDTLKLYYYRGNYTMFRKMYEQTKANRIKEYEKQEKKIKEMKKSGQSTKQAEKKTKQQQMQKSKGKGGKKDDRDDDESLATMNLIARPKDYIVKFRFPDPPPLQPPILGLHDVWFKYPTSKDPIFENIEFGIDMESRVAIVGPNGVGKSTFLNLLTGVLEPTKGEWRKNHRLRIGKFDQHSGEHLTAEETPTEYLIRLFDLQYEKARKELGSFGLPGYAHTIKMKDLSGGQKARVALAELKLNAPDVLILDEPTNNLDMESIEALTDAINEYQGGVIIVSHDERLIRETNCQLWVVEERGICEIDGDFDDYRKELLDSLGETINTNPSAAANMSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDZ2</accession>
    <name>A0A1D2NDZ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endocuticle structural glycoprotein SgAbd-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03196</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000072">
        <property type="protein sequence ID" value="ODN03471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDZ2"/>
    <dbReference type="OMA" id="AYTGEHR"/>
    <dbReference type="OrthoDB" id="7998177at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905418" evidence="3">
        <location>
            <begin position="25"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="35494" checksum="D6241E7F32A79E47" modified="2016-11-30" version="1">MARLSSITRSFALLISLVILSVQGGPPAKRSYPLPSVSDAHYQEILSDGSYKYAYTGEHRYVAERRLADGSVEGESLYIRPDGVPIKVHYFADGQGYRPKTEVLYKERLTTARRIPVVATRKVVVPEVREVVDVISHPAVVVAPPRSDNSVRVNLADARSGQGVNVASNGDVAAAVPSITAVIGPGSHAVISPEAEAHSGSNGFFRSAGGSGSAALANPQVTAIAGPGSTVVISPKSRASTGNAVPVVERVIAPHVVERVQPVLTTARKVVATHAAPGYVYSAPPAVVAAPTVTAVRAQGVLVIPPKPSYSYTYSYSAPDGKHPQRDNSAYVNVNVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE94</accession>
    <name>A0A1D2NE94_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE94"/>
    <dbReference type="STRING" id="48709.A0A1D2NE94"/>
    <dbReference type="OrthoDB" id="10255247at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035253">
        <property type="term" value="C:ciliary rootlet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097542">
        <property type="term" value="C:ciliary tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033192">
        <property type="entry name" value="ODAD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1226" mass="142325" checksum="9A495B21125C07C7" modified="2016-11-30" version="1">MINRGTYILHRLVMSWLHKTQSTYGRLIPKPEVLGKREEISDEAIPIQDQIENLRAKISLKERYNKALRDDLNESNEGASSYIHELTAETKELRQKLMDAIDSEKSAVQNALRTHREFQLAMTNKTPAVAVPWLDDKLFDMAKLLNSLLDKLKDKRKRLEESEQMVITIEKWPRPGTLPWEVEAQANFSRLECLIESQKVKRETAFILHSKYHEIKFHLLAERGKYTSILKNMEMGLRTLKNELSSLETMLDDAIYFRNEAYKNLTLTEKEASENRKRRRIQMSKMKKAVERILEENQHAPAKKPKEMRASVSVPGANLSEVSELLRAKRTEVEEFQGRARRLVETMRVPDLTHIPIRLKTVSKIGMRLKDELDSKEKLRDLYIKQRAQLNLILYYFRYTGITQLEDYNSFHKEYEKSISDAVTRQQDVIRKLDKVGSINLELRLGILAILDHLNMERRKGRAQYPRDDMMTQMKIVIVKLRKLISSNGELLDLFKNKEPERNYSFYVKPLFLPNRLIRVGTPHQSEESDADDDFVDSKVPGRVEIKAKSARFLNQALLKRDIMTKPEIVCAAMYDLFISYLSFQFNSSPFILHTNMAFEPYLMNRKQSCFRAPACYSRYPRLPTYDPNCTTDKYTGYFRDRWKALAQNACSRPCSDKPLCPLVLPCGMEKKDVLSQLTDPKGMLNKAVTNLNDICIPELYDSGLTTHNKTYQYPWSHNNVDDCCKAECPCLDTFPEAPQIDYVCKGNFPCPPMEDCTTYKHFFPPKPTPCPPRRYRPHPYDPCECPLESATSYRLDYEHKDPVQNGPVLAAAIKRGMWSMDQFCQDFKDDTEVKSEFTRKCQKVRQPIINQATLKCGPGRMDGSAETCSQYVLKCGDRPCYPEWIENDIWMPPESPLETCTTYKHFYKPHCFPPPDNKKIKSPDAIPFSSMNNMWYTCCDPEVDQRVPVEMRDQDPWPIVRTCPIKYQNNLQTDPCAPFRDETTYKADYFAKKRCAPNKWFGPSRGYTEPILPFNDTTINRLSYPAYSPDQYKGAKTDSGNPNGILWGPYKCPPGADKCRPRFPPPYGHPLKPYTKQCPCGQFDDRSMYHRDFKFWTPEMVDQVNEEHCRTIDIPKGISLYRASYVEQGGKKAAVMPPPKSTGQRCMNPCAFRDLDPLYRLSYKDFWKAIPRESLEKYRGKPTIKTRVRKGEDCQPPPENITLFQMPPGTTVEETLNYLAQQGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEB1</accession>
    <name>A0A1D2NEB1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kynurenine formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEB1"/>
    <dbReference type="STRING" id="48709.A0A1D2NEB1"/>
    <dbReference type="OMA" id="WRTDDIP"/>
    <dbReference type="OrthoDB" id="7108654at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118:SF12">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="526" mass="58410" checksum="DD19330AD75FBAD4" modified="2016-11-30" version="1">MNFGPLIHRWEGRKSSWYVEAEGFTAGGFWVASKGFCTSEHTSTHIDAPYHFHKEGRKLHEIPLEDMIDIPGVMIDIYDKVHKFKDGKLNVIENYALTQDDVLEWEEKNGKIPQGAIVLLRTGWESRWGDLKQYRGEKDLGTTAAPTNNETGDDDKTIPLDVNLNFPSFDVSSARYLAVERQVLGVGVDALSIDPGNTKTFPSHRLFASRNIYMLEMVANLHTLPPKGFNLWVVPFKIDFGTGAPTRILARLNNCALLLMLAGSFISVVDARARFQNNAGAGAAGAGTRFIDLSHAFNNETAVWPGRKITFFNEFGGRDENGIWVVSNGFCTSEHTSTHIDAPYHFNENGRRLNEIPWEEKNGKIPQGAVVLLRTGWESRWGNEKLFRGEKEGDATVVPAADSIENNELEPIGTGKSTQFYDPDVAASFAGKLSFPGFGVTAAKFLAEERSVRGVGVDVISIDPGNKNNFSPAHVTFASRNIYMLEMVASLYTLPPRGFNLWLVPFKIDRGTGAPTRVIARLNEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFE9</accession>
    <name>A0A1D2NFE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Solute carrier family 41 member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02651</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFE9"/>
    <dbReference type="OMA" id="ADYINMN"/>
    <dbReference type="OrthoDB" id="666972at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.20:FF:000001">
        <property type="entry name" value="Solute carrier family 41 member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228:SF7">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="10">
        <location>
            <begin position="206"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="10">
        <location>
            <begin position="417"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="569" mass="62412" checksum="C885354810B1412C" modified="2016-11-30" version="1">MAFNAENMSEVQKRDSGCWDTKTEVNSEDEAQVTIHPNPPMIISINETLTSNGYLIEPYELDVDLSAKENQKNLKANDNTDCGIFMTPESGNPNEQHYIRKNSITNSIIGGNLFGAIGEKGSCRSVTSIMISSSIGSAESRSSLISGGRRGIPGLNHEPWHKIFRDIFIPFIIAGLGMVGAGLLLDYVLGWDVYRDIPELTVLVTPFLGLKGNLEMTLASRLSTQANLGNMNDKRQKWRICFGNLALDQLQAIVCGLVASFFALCMNLVKTGEWPLDHLLLLTSASILTASMVSLVLGSIMVTVILLSRRFKINPDNIATPVAGSLGDVVTLWMLSTFSSVIWTMIQNGEYWIAYVVYAVYLVIVPISFWIVYNNEFVKKVLISGWLPVIISVVISTGGGVILDISGNAYENLALFQPLINGIGGNLVSVQASRIATQLHAECERKILPNNGRICQAPWSVFTKGVHATSARVLLFLVIPGHIFFVTIAWAVRLYPGGQSYDVLFLFVFLVAALIQVAILLYFAKVLSNFMWRHGQDPDVSTIPYLTATGDLLGTGVLFLAFLILSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFG1</accession>
    <name>A0A1D2NFG1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Translocation protein SEC63</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_02956</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000065">
        <property type="protein sequence ID" value="ODN03716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFG1"/>
    <dbReference type="STRING" id="48709.A0A1D2NFG1"/>
    <dbReference type="OMA" id="RAILHAH"/>
    <dbReference type="OrthoDB" id="1734229at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000063">
        <property type="entry name" value="Translocation protein SEC63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000011">
        <property type="entry name" value="Translocation protein SEC63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
        <property type="entry name" value="SEC63 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF0">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="11">
        <location>
            <begin position="104"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="492"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="730"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="526"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="563"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="602"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="737"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="769" mass="87882" checksum="C7ADCC58946EAD62" modified="2016-11-30" version="1">MGQKFQYDESGNTFLYFVMAFLGLILIPCSYYFWPNPDKPKEKRSGVQCNCDACIVKEDVLKRKEPRKKLKRLAIRIALSLGWILFAFVAYKITQTDYEYANFDPYEILGVPLSASTAEIKKAYRKLSLLYHPDKETGDEKLFMKLTKAYQALTDDTARRNWEKYGNPDGPGAMSFGIALPSWIVDKENSVWVLGLYALVFMIALPTTVGIWWYRSIQYSSDKVLLDTTQLYYYFFHKTPQMQLKRALMVLAASMEFEKGHNSQVQERVSDNLEVPALIKQLPNLNEKNKERPLCFHYSVKARALLHAHLSRMPLPPNTLEIDRQLVIRKSPYLIQEMVTCVSQLIMLAHAGRIGRLPTLDTIESVMKMSPMIVQALWETRSPMMQLPHITEDMQKYFMSKKRQISTVQQFCQMKDEERRNILKGLSDDQYVDVMRVCASMPLIDFKVQCEVLDDEESAVVTAGAIVTVTVTLTRNSMSSLLKGENAAVKSSQALAAAQDDQDEDKENREVDADGNPQQVQNKKPVWQKKKGGGKKPGGKGKNPPQKKNAVVVPAIKAAKNAETPEKSEKPKEMKALPDYDDSDDEGGASDGSMSDSDSGSENQNKEMATSGNEDDDDEWEKCQSRLAKNKERALEGKSKISHPVHCPYFPEVKQEYWWTYVSDRKNKQLVTAPYLVTNLIRVEECQLQFTAPRKPGHYKFTVCLRSDSFMGFDQLREIKLDVQEAKQIEEHPQWEMSDEEEEKEVESEESEYATDDDVDVDEEDEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFH7</accession>
    <name>A0A1D2NFH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 6, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02678</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFH7"/>
    <dbReference type="STRING" id="48709.A0A1D2NFH7"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="9">
        <location>
            <begin position="27"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="11640" checksum="F001FE3055700D18" modified="2016-11-30" version="1">MSDEEQPQPKAKDACLAQLDDDFGGGDPQEKYRELCRRTTECTKFLKKLTECNDRVNSKTKTEEKCIEEVMDYMHCVDYCVSDWKNLSCTAAKRFFPLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFJ6</accession>
    <name>A0A1D2NFJ6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">Ocin01_02663</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFJ6"/>
    <dbReference type="STRING" id="48709.A0A1D2NFJ6"/>
    <dbReference type="OrthoDB" id="5823345at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF36">
        <property type="entry name" value="INNEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN04033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="378" mass="43630" checksum="3258D7B214066397" modified="2016-11-30" version="1">MKFGAVFDTDDEISFFNQWLFKRDSTLIDNIVFYLHYHVTAALFLAGCLIVIVGTYIMDPIDCIADQAVIDVIDNYCLYHSTHTFVGNPEDILTAHPGVSAKNSLESEIKFHHYYLWVGLILGVQATSFYIPRGLWKTWESSRVSTMLKEKETLLAEPSKEEKDSSDVLITYFRSKNHSTYYLRLLICELLNLSNAVVQLTITNMFLGFGLLNLKLDVLQLLRETRPLQRSDAIDQMFPKVTKCVFYSYGASGNVQSYDSLCVLPVNAVNEKLFIIIYTWLWLLISASAIAVFYRIIFLWSSFRVFMLKFYMQETRDRSMILKKLESTLGIGNWQLLNQLSGNLDSWELTKFVERLHAGLNKIESKKEEKDEGESTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFP4</accession>
    <name>A0A1D2NFP4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Atrial natriuretic peptide receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02627</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFP4"/>
    <dbReference type="STRING" id="48709.A0A1D2NFP4"/>
    <dbReference type="OrthoDB" id="1890790at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF494">
        <property type="entry name" value="ATRIAL NATRIURETIC PEPTIDE RECEPTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26195" checksum="31F8F17AA8F0E470" modified="2016-11-30" version="1">MSHAREIARMALALRDAVRRFSIRHRPKEQLKLRIGMHTGLVAAGVVGQKMPRYCLFGDTVNTASRMESNGEALKIHVSQQTKEALDYFQCFILELRGEVEMKGKGKMTTYWLTGERQSQDLQPELMDTSCTSVSNMGEGVSSSTNINLHMNTVTTSAAVSPLAMSTSPLNAVTVDHTSVSATTCTSPDNNCSRDKQSVCFEKDIPNSIIIEPNKRPSKEHQETNNISKSVSSSLIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFT6</accession>
    <name>A0A1D2NFT6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sorting and assembly machinery component 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02504</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000053">
        <property type="protein sequence ID" value="ODN04148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFT6"/>
    <dbReference type="STRING" id="48709.A0A1D2NFT6"/>
    <dbReference type="OMA" id="SGIWRQI"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033108">
        <property type="term" value="P:mitochondrial respiratory chain complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.50:FF:000002">
        <property type="entry name" value="sorting and assembly machinery component 50 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.310">
        <property type="entry name" value="membrane protein fhac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="9">
        <location>
            <begin position="134"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="456" mass="50098" checksum="EA03F083BD6BAABF" modified="2016-11-30" version="1">MGAGQAKTRKQPQGVAKPSDGVSIDLDTVPVRVENVKINGLSRTKDDYVSQSVQELFKATTFNELVFKASVVQGKLEKLGCFRDVGIIIDVSDSSPDGYEVIYNVRESGRFVGGINTMIGANEGSLVLGCRLPNILGRGERINLEHTIGSDSNKSSLLTAVKPLGGSWNADISGTLFHHKNPAYWSSYTVFSTGALLDFAFESAQKVRHNMQWEGAWRQLEASSRQTSFAVREQSGHSFKSSLRHIMTVDHRDHPIFPSSGVLLKLVQEYAGLGGDVAFVKHDSELQANIPLPHNLVLQGALRFGVLRPLDARDSTHNISDLFFLGGPQTVRGFEMRSLGARSGSDALGGKAYWASAVHLYMPLPFGFGRGSFGEYFRTHAFVNAGNINDSSFNTEDFAQSFQTMMKDFRASYGIGVAIRLGQLARIEINYCWPYRFSKGDRLVRGVQLGLGIDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGP0</accession>
    <name>A0A1D2NGP0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein Skeletor, isoforms B/C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGP0"/>
    <dbReference type="OMA" id="NARIGPT"/>
    <dbReference type="OrthoDB" id="2448405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019545">
        <property type="entry name" value="DM13_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052126">
        <property type="entry name" value="Spindle_Org/Thrombomodulin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24036">
        <property type="entry name" value="SKELETOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24036:SF5">
        <property type="entry name" value="THROMBOMODULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10517">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00686">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51549">
        <property type="entry name" value="DM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DM13" evidence="4">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="3">
        <location>
            <begin position="156"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="546" mass="61494" checksum="3DFA3BCC3E5CE7C7" modified="2016-11-30" version="1" fragment="single">RDLPFFRLKHTFYHSNLHYDGAGPDAFFWVGTGDEPNTSGRKIPNEKGSLDVLNGYEGEDIELKLPDDLTVYDIDWLSVWCVAYKHNFGHVRIPRHEHELNVPPSLDKFKIKKSIYTLPPHYNTPRPTYNFNSRATPKSSSRPKDGFSNCKDLLEGSVQLQWDWDGDEYVKFKLSGRITEKQWVALGFSPLKGRTQMVGADAVVVYFTPHAREKYHADDYFMSAKSQCDGKDGVCPDKRIGGSNDIQVLHGARKNGVTTVMFRRPMRARDGFDLALEDDEVNIFVAIGNLNGRNEANYHFGERTGPEEDIRITPKGKGDHSCLTIIDEMPTDVGPRLKSWPTIVIEGVTNFTARIGPTGGKRGYTAITGNPSWGICWYLNDQLIPEIYVERGETYHFWVEGGDDNKNPSRYHPFYITDSAEGGYGQKSESEQALQKIYAGVGFDSSGYPYPLAAGRYCEWEHKTIDKSSQSDTFESYFKTLALNCEDGRPSSLSWTCYTHNNLGWKIHVLDKGRTRRDKISSTGASSLAANRGLVVLPCPTSFSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHG2</accession>
    <name>A0A1D2NHG2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000038">
        <property type="protein sequence ID" value="ODN04652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHG2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905570" description="Protein quiver" evidence="2">
        <location>
            <begin position="25"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="18531" checksum="81DF96ABA9785301" modified="2016-11-30" version="1">MFSTYWKCTRVTLLLIITSEIVLADFNTTNTTKVLTCYTCELLGCFNSGRDNATWIHITPCPPDHKCYKQNIRKLVGHYYGIWIWNKYIYAVKRSCINTIEADAILANVNNTCKGPFVDEDFEQKECICDTHLCNKTSLAKTQLLSVVLGSLYAFLLGGVILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI65</accession>
    <name>A0A1D2NI65_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copine-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI65"/>
    <dbReference type="STRING" id="48709.A0A1D2NI65"/>
    <dbReference type="OMA" id="YVELYYT"/>
    <dbReference type="OrthoDB" id="1562946at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800:SF5">
        <property type="entry name" value="FER-1-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905590" evidence="1">
        <location>
            <begin position="18"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="184"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="342"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="475" mass="53099" checksum="202266982BBBB73E" modified="2016-11-30" version="1">MIRTLCVAALVAATVQAAPIDTIKLRFKISARDLPDKDTLGTIDPYVQIFYNEDGNKEETELGRTGTVTDNENPDFGDEFEFEFVRAKRQRWHFKVYDHDNAREDDKAGEAYIDVADYVDKNQHLNVNLNKKGYLILSTLDQLPPVAPPAPVVQTVPVISPVPTHVQQIHTVPIVQPGVAVLPSTGGVLLVPQPHTITVPEKAKLRFKVSAKDLPEKDKLGSIDPYVELYYTEGASTKESRFGKSSTIDNNKNPQWGEVFEFDYDRSKQQKWHFKIYDYDQGKEDDSGGKVWIDVNDFVQKGQTITVNLSKKGTLTVTNVNPQTTPTQQTLHHVAPVAPVSPVAPVAPQAPVIQVSNPLTRIKFRLSASGLEDKDILGTSDPHVKVFSKIGSQPEQLVGRTAKLDDTENPVWPDTIDFEYEPSQQPKLHFLVLDDDDGRRDDELGDAWLDVNEYVKKNQDESVSLKKGILNIQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIS1</accession>
    <name>A0A1D2NIS1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sodium-dependent dopamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01549</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIS1"/>
    <dbReference type="STRING" id="48709.A0A1D2NIS1"/>
    <dbReference type="OrthoDB" id="6494165at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="213" mass="23702" checksum="DA58D6B22A8142D6" modified="2016-11-30" version="1">MTEVKAENNEIKEESVITPVPPEEELSPTPEPVVEVIREQRIIVPKVILPPAIDPEIEAVLLEEEDENDLNQHFFIDQVHWQRPTWGNSWWFGRCAMIALAVDMSAIQSFPRHVANQGGIIFIVMYVLCLCVFGYPGVVFEGLIGQHFQTGMLGIWGLVPLLRGIGVAVFSSSLVFAALAPSNVMWSAIMMIDSCKALATGHLPWESCNNKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ72</accession>
    <name>A0A1D2NJ72_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Active breakpoint cluster region-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ72"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ72"/>
    <dbReference type="OMA" id="VSFASCH"/>
    <dbReference type="OrthoDB" id="2155291at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.555.10:FF:000004">
        <property type="entry name" value="active breakpoint cluster region-related protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037769">
        <property type="entry name" value="Abr/Bcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23182">
        <property type="entry name" value="BREAKPOINT CLUSTER REGION PROTEIN BCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23182:SF1">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 1A, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19057">
        <property type="entry name" value="PH_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="17"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="399"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="605" mass="69286" checksum="8C8E78857728312C" modified="2016-11-30" version="1">MVQPEQLHHGQDRSPRHLVKNSFIVELSEGHRKLRHLFLFNDVLVCAKYKASGRNEKFTFELKWYIPVMDCMVVEECSEPRESAPINLVALRSQASTVRDQIKRQTSRDDPKKSKAEKQRKKLAELEAQLVLASPNLVFKVKSGNGRAYTFFLSSEYERCQWVDAIEINKVSHLNNMVVFEFLFAIYFAIYYTLLASQSASGAQLSMHELQSWLTSCRKDLKTNMGSYLLRTGRDENLLVGDFYVLIGQLKGILRAAGESNAFKFSILIVKNVSDLTLCINFSDLYICVEVDSYGHFFRKAKTKMICESTTPNWNQDFVIELEGAQNLRILLYEDHPRRGTLIRAKNTIELNRSWLTATTSERKIELHDYVLTVQTRFIPSEMTIRRVPTAKPSGLFGAKITQVCKREKRQIPFILTSCVREAERRGINEVGIYRVSGSASDVSRLKKAFETNSYEAEQLLKEVDIHSVTGTLKLYLRELPEALFTDDLYPRFFEAFNLQDQELRKTTLLQLFSTLPPLNQHIVVFLLDHMVRVNSHENHNKMSLHNMATVFGPTLLRPGAKNEGASNLDLLAAGTVDVMAQAGILYFFLTRRCNNEPLQPSQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ79</accession>
    <name>A0A1D2NJ79_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ79"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905649" evidence="1">
        <location>
            <begin position="21"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="327" mass="37642" checksum="A9873E9019CE21E3" modified="2016-11-30" version="1">MKVSLLYGVLVWIHVTGINCRPEPSPDAAHPIHVKRNDSLEIYESSVDYTSMNTSALSESDYTKDERRKLLAALAAPIDDTESDESFPIITAPGPTEDGKVAYPELKLPIRLDLPPSKMFVLAETLVNITTNTCPLVMSMLMIRVKSGDEEPLSPIEEYFFELNYHYMKKCENYTRSHPIVQKVIEPDYEEYTLEVHVDDDNRTFATLAGKGKSANKRLKRDVEYDESKLVYRLTKDSNMFNKFLRYMANVMRPACSHVALPDNTFLSHFMFDMSNRVVEFSDKEHMESALTKYWKKATPVFNQILSCMREVDYREESRGHYSEDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJD3</accession>
    <name>A0A1D2NJD3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glycosylated lysosomal membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_01606</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts (via lumenal domain) with lysosomal protein MFSD1; the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Lysosome membrane</location>
            <topology evidence="9">Single-pass type I membrane protein</topology>
            <orientation evidence="9">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GLMP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJD3"/>
    <dbReference type="OMA" id="TLHYLWD"/>
    <dbReference type="OrthoDB" id="6264340at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029382">
        <property type="entry name" value="NCU-G1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31981">
        <property type="entry name" value="GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31981:SF1">
        <property type="entry name" value="GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15065">
        <property type="entry name" value="NCU-G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <keyword evidence="2 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905644" evidence="12">
        <location>
            <begin position="26"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="396"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN05076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="436" mass="49064" checksum="0F77382F2E19A522" modified="2016-11-30" version="1">MKSQLIATSLCFLASISFHGYSTLAEDHVPRKFSTEINPGCEAVFGTNCSENSTINLVHIRSDGPHDTLHFLWSFLGAPSLLLVRTPLQSNLSVDWTSIFEDTGSGGGISFEPEPYYLFGWSLVKVWVYNDQNDTARLDKADQSDVEGYDSKNFVWNRKDNSSILNSTMINLSFEARSYDHREGEANGVEQMGPNGFFRITIRMKSTEDYSKVLPYMMYNENSTQVDVAFNDVQLNTTAEEYPKHPRIALKYIMVQDNGNRNGEAGQMKLDVTKTLDDEHSPGVFEVYSINTPAKGYNQSYIQWRPICYTAEVRDVIDSVDVEAYPLQHASSVLHDDNVQDSILWSYFGTEIDNVTFQSMNISFGTVGDGFYNKTKHISWTYSTGFGVPPPDRVSLLVMLVVSIGLGIPALIIVLSVIYMVMCKVRRPRDDLLLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK69</accession>
    <name>A0A1D2NK69_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Signal-induced proliferation-associated 1-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01089</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000020">
        <property type="protein sequence ID" value="ODN05612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK69"/>
    <dbReference type="STRING" id="48709.A0A1D2NK69"/>
    <dbReference type="OrthoDB" id="2499658at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06745">
        <property type="entry name" value="PDZ_SIPA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11210:FF:000002">
        <property type="entry name" value="Signal-induced proliferation-associated 1-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050989">
        <property type="entry name" value="Rap1_Ran_GAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711">
        <property type="entry name" value="RAP GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711:SF22">
        <property type="entry name" value="RAP-GAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21022">
        <property type="entry name" value="Rap-GAP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="5">
        <location>
            <begin position="717"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="1075"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="372"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1198"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="373"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="402"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1227"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1255"/>
            <end position="1265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1279" mass="139133" checksum="25493C1237A75971" modified="2016-11-30" version="1">MNFLGGSHGSMSTSGGSNLELVGPGEAVGGRAVSANTAVAGGVTNSSPYIRLSSLTHHQVLQQQQHQQQHSQHHSIYQKVVDPSTLQSNKGSFLNKSTNNPDESCSSSAATPVIKDTPTYEIHDNEPYVVTVRSSPSRSLVKSVSGSSVPSAPAGLKVFSGVSKAGPRLALYRSNSSLDLLDRDNYLNNQARAFHHSHAHQLSPQQRLNLVAQSQVHAATGVGVSTGCFTRRKDFGSHGSIDVLSAQNASLIHGGGGHTTRSGSVGGSTTRPFLSLMNQSSGGLLVHNNKGGTVEQVDGGGSGNGIIEESKSLPVVGEASDGMTTKVVLRHGTNPMEERYRRRALAHYDCQSISANISYAARLRSLLSKRRNTTTGASAASLGQRSPPESNGNNASSSTINGGLSPSSGGPSLSSLAQSSSQNASSSSSSGNLLQVPDHQDSDLGDGKSNALVLSFCLAYIHFGFNIQLFNACTLHTLRNQNNSCPYFRNETGGEQERIVSLTKLSRTAANKPATGYRKVGIYGKADDVDVMGKGPFVAPSDEATHRSVSCRNLALLEWRNGATHWQHGICPYAINVQATKQNILEAVDVGATYYREYFNKQDHENWFGLDENLGPLAFSIKKERFDNQLYSNLNHHEGKSGIVASSGPKCLFRVIIRSTELNTIRGSVLDESIPGIKPNSNKGGTHAKDVLEFLLPEVQLSCLKLGTSGPQTEDLLLKLDEQVLTYRHKVGIMYCKAGQSTEEEMYNNESAGPAFNEFLDLIGNRIRLKGFDKYTGGLDNKDDSTGLHSIYSQYQGCEVIFHVSTLLPFTPNNRQQLMRKRHIGNDIVTIVFQEPGALPFTPKNIRSHFQHVFIVVRAINPCTDSTSYSVSVSRSREVPLFGPPIPAGAKFPKNQDFVDFLMAKVINAETATYRSEKFTTMATRTRQEYLKDLVSNFTTSTPIDPRSKFSLMAFGASKKKDFSKPLRFIGDTMLQGALSWAVYLEDTFKGCRIDAFLGISCDTIVIIDALTREAVFAIACSSLSVSSIYSLRLYYHQGECVTIYGKETSSISEGDLQEIVNRLEIVTKGCETQEFVLHRNEVGQLGFHVQQDGVITEIESSGHAASVGLKQGSRLVEVCNVVVATLTQDQMIEWLKKSTSVPVLVIPPNLNNTPRRYVPEYAFDEDIKQGCDSKHCVFTLEPEGEYENIHLKNGVREDGESSYSKSPHSHYKSNAVNSHRKRYEPRSFSPPRSSNSSGYGTGSSSKSFSSGNGDTHHVSPHHEFSNILGNVDGKFSWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKH0</accession>
    <name>A0A1D2NKH0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00943</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FKBP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKH0"/>
    <dbReference type="STRING" id="48709.A0A1D2NKH0"/>
    <dbReference type="OrthoDB" id="8116123at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034587">
        <property type="term" value="P:piRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042282">
        <property type="entry name" value="FKBP6/shu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674:SF1">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3 5" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="125"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="498" mass="56590" checksum="DFB5EB62FB6AC839" modified="2016-11-30" version="1">MELNVTEITEDFAHLAHVHSARPRFQNPAQLTKMKMGEGMAFDIDSMELEDGLEEDEEEVYDDDVLAMFSFGDVSEKEKMTTNTDLFDVEKSAHRDFPGTEKLMTPLNKEGTVIRQGSELQVPERSKLYFHYASICEGDDEVFDTTMSRKYPNVMDLRKETTIPGLALAVKSMCLSEVSRFIIYPEMAFGKAGCPPRILPDAKVMYVIQMLQFVEEAKLNTLHYMTSDERNQLPFEQIVKVAKDFRGEGNRHYQDQNHGSAIKKWRKALNMLEDYPVTTEEDDKVRREYVWMLYSNLAQSYLKLERPAQACSACKIGLKSAVENDFSSAKLLYRFAKAKLMLKDHDAALGLINQALKIEPKDRESIELKSQIVLESGRGMEMFKGIFKSNGKTTNGMSKGTQVQAVVKTYNNPDSEAKVNRRLKNLRSGYDLDDWVEDLAFCTASQKELVEMDAEKAVAGSKRSTSRIKPVLLSKFHLSTIFKSIDEELKSAESGNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKM6</accession>
    <name>A0A1D2NKM6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKM6"/>
    <dbReference type="STRING" id="48709.A0A1D2NKM6"/>
    <dbReference type="OrthoDB" id="6630845at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905684" evidence="1">
        <location>
            <begin position="17"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="174" mass="18530" checksum="E620799574D68CF8" modified="2016-11-30" version="1" fragment="single">MKCLAVLCGLLAVASATPGAIQYHYANPGGVTYRGTGLGAGFQIGVAQPVAAPVQQYAAAPVQQVAQYAAPVQQYAQQVYQPTVAVQQKVGYANQQVLTSVPGVANVPVTKLALTQGVTQKLVDVAQPAVKNRRVKVRRPALRKEFYDIEHRIIVRPAGSATLELSQPISKEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKP1</accession>
    <name>A0A1D2NKP1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00993</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKP1"/>
    <dbReference type="STRING" id="48709.A0A1D2NKP1"/>
    <dbReference type="OMA" id="EICGHQE"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF10">
        <property type="entry name" value="PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="53"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="488" mass="54374" checksum="4714666F651D9E34" modified="2016-11-30" version="1">MKFMHCVSKTILHQQRCKVHMSSLYRPVIVAPPPSPKTASEKTKKGVRKDEQDSLSKSLRLLIDNGVIGPSSCVGAYHLLPFGLKAMEKLTKLVDNHMIMANCQKIQMPVLTSSSLWKATGRLEKCKPELMRVVDRHSKEFLLSPTHEEAICDLIKNPPLSHKQLPQRLYQITEKFRDEARPRFGLLRGRQFLMKDLYTFDTDLEAAKQTYDEINQVYSKLLSSLDLQWMQAHGSTGTIGGLNSHEFHVMSEIGEDSILQCSSCNEVFNADLSEDQQEDQLEATGSGSVSQASTTSDPKCINCGSTALSSSKCIEVAHSFLLGTKYTKPLSALYITEENKKVPMEMGCFGLGVSRLLAASVEVKSTMDEIRWPLRIAPYLVSIVPPKQGSKEDVLGTPLAVQMYESLKKILPNDVIYDDRTNQTIGKRLKDCKKLGIPYVIVCGQSVQDPLGPLMEVHDVNAGISSLDHSDKIAKQLYDINSSIKRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKT2</accession>
    <name>A0A1D2NKT2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Failed axon connections</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_00866</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000015">
        <property type="protein sequence ID" value="ODN05847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKT2"/>
    <dbReference type="OMA" id="ENTFRTW"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03193">
        <property type="entry name" value="GST_C_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="3">
        <location>
            <begin position="31"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="2">
        <location>
            <begin position="175"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="29315" checksum="EA7E65531B8F004A" modified="2016-11-30" version="1">MKAKWREQSKQGKVILHGMYGNSDVLPTPSPFVLKLETYLRLTKIPYEVDKVDFWGPKGKTPWISYEGEHLADSQFITEFLSRKFGKQLANKYSIKERAIGTMTRVMVEEHLYWAGVMWRFAFGGKDTFQKVLRGEKSFIQWLIFRLIAPQMRSSAWSQGVGRHNETEIKAIMLNDLRAISTVLGQNKFLLGEEPCEDDCSVFAGLASAVFSTNSPLEKELNDELSNLKEYCYRMKDLLWPDWESHMNKLKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL86</accession>
    <name>A0A1D2NL86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proteasome activator complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00598</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PA28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL86"/>
    <dbReference type="STRING" id="48709.A0A1D2NL86"/>
    <dbReference type="OMA" id="SESQAFM"/>
    <dbReference type="OrthoDB" id="6591885at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008537">
        <property type="term" value="C:proteasome activator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061133">
        <property type="term" value="F:endopeptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000045">
        <property type="term" value="P:regulation of G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.180:FF:000002">
        <property type="entry name" value="Proteasome activator complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.180">
        <property type="entry name" value="Proteasome activator pa28, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003186">
        <property type="entry name" value="PA28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036997">
        <property type="entry name" value="PA28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009077">
        <property type="entry name" value="Proteasome_activ_PA28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036252">
        <property type="entry name" value="Proteasome_activ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10660:SF2">
        <property type="entry name" value="LD45860P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10660">
        <property type="entry name" value="PROTEASOME REGULATOR PA28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02252">
        <property type="entry name" value="PA28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47216">
        <property type="entry name" value="Proteasome activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome activator PA28 C-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13647" checksum="A94292692C5BFBED" modified="2016-11-30" version="1">MWVTFLIPKIEDGNNFGVSIQEDTLGEIRAVEGEAATFYDAIARYHINRGKIISKVAKYPHIEDYRRVVAELDEKEFLSLRIVLSEIRNHYAAMYDLIAKNWEKIIRPRTSNAENLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMH7</accession>
    <name>A0A1D2NMH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glyoxalase domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_00182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glyoxalase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000004">
        <property type="protein sequence ID" value="ODN06483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMH7"/>
    <dbReference type="STRING" id="48709.A0A1D2NMH7"/>
    <dbReference type="OMA" id="CDAECNG"/>
    <dbReference type="OrthoDB" id="1545884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16357">
        <property type="entry name" value="GLOD4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043193">
        <property type="entry name" value="GLOD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043194">
        <property type="entry name" value="GLOD4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46466">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46466:SF1">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21701">
        <property type="entry name" value="GLOD4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="3">
        <location>
            <begin position="5"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="3">
        <location>
            <begin position="139"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN06483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="33053" checksum="CBF86405236E4031" modified="2016-11-30" version="1">MSERRALHYVLRIGKRKEAMSFFKNVLGMKVLRHEEFEKGCDAACNGPYDGKWSKTMVGYGPEDDHFVLELTYNYGIGSYRKANELRSIDILKADLKPVLAAGGIMERIKRDGIEEVDACTIDYEDYKFRVFENKTADKIDRVILATTNMARTLEFWNGTLGMSNENDSLSYSPAQCKLQFEIYSLSEADRTEPFGRTAFACPTEQLKPIEELVSNSTDGSKVLTSFLTLPTPGKADVHVVILQDPDGHEICFVGDEGFRDLSQVDPAGDQLLEDAIAADKSDEWFAKKGGKDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMN0</accession>
    <name>A0A1D2NMN0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00186</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 7"/>
    <dbReference type="EMBL" id="LJIJ01000004">
        <property type="protein sequence ID" value="ODN06487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMN0"/>
    <dbReference type="STRING" id="48709.A0A1D2NMN0"/>
    <dbReference type="OMA" id="FGAEGNE"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000008">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000013">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF9">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4 8" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="61"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="178"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="364"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="433"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="477" mass="53104" checksum="A9DC401E3E82B005" modified="2016-11-30" version="1">MEEAAITTDEVIPEQDILAPLINDKCEDISKEGDSRKLFIEFLESVADETGKSVEEIPGDGCEVLVHYIGTLPDGTEFDRSDKRGKPFSFMLGEGAVIKGWDVGIAKLGRGQRAKLYIHPDYGYGANGSGQIPGNSPLIFEVTMIDFKPEDLTSSKSGALLRSRIIPGKSKFLNPNDGSSLTVTLIGEYEGTKFDERTVTFVLGEGGEHNIPYGVEKALFKFSQGEKSRLTLGPKYAFGSKGSAEFNIPADATVQYLVELISFERTREAWQMDPPEKLEAAQKAKDKGTAFFKEEKFNLATRQYKNIVNFLKTEASLEGDDEELRKSLLLASYLNQALCHLKLNEPVVAKRNADEAIELSVNNPKAYYRRGLANLGNKEAYDAKADFQKVLEIEPDNKAAKQQLAVCDKLIKQHKEREKQVYSKMFEKFAKMDTEKEQAELRKQPNGLDNLDEWQKGSSDKMDVDENSAPPAPASQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMP6</accession>
    <name>A0A1D2NMP6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine-protein kinase SBK1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00309</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMP6"/>
    <dbReference type="OMA" id="HETACKL"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="336"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN06365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="375" mass="44031" checksum="230DBD8033B5CEF3" modified="2016-11-30" version="1">MYVDLEREFDLLQEVGEGWYAKVFLVEHRKTRSEIVLKALHKDYISKKDVIREFHYSYNLGTLNTAKVLVRTFDILFISNDCYVFAQEYAPFGDMTSNVSDIGIGEIYTKRVAKQIASAVDFLHDHHLVHRDIKLDNVLVFRSDFSKVKLSDFGECRKKGSLLVRFNEWVPYCPPEIVNTPQDTSYSVEFHQDTWQFGVMIYLCLTGNIPWQKADARSDPRYQAFDLWQRSRVTKTPKGFKIFSNKARRLFRKMFDLNPSKRVVNLNDEMQKYSEDKWLTKVPEKPMDEDELSTNMSMLSFHSSLTDKNRLLFTLTRYGVETTVDRDMKKDRIKEWIASSTIEEEEPDEEEEWDMGSDHVTSSHNSNQSSSHQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMW0</accession>
    <name>A0A1D2NMW0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Discoidin domain-containing receptor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMW0"/>
    <dbReference type="OMA" id="TATDAWC"/>
    <dbReference type="OrthoDB" id="6071166at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00057">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24543">
        <property type="entry name" value="MULTICOPPER OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24543:SF291">
        <property type="entry name" value="SMOKE ALARM, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01286">
        <property type="entry name" value="FA58C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="14617" checksum="3B8B948B81853FB3" modified="2016-11-30" version="1" fragment="single">LNRETQGGAWCPKEPISIGIREWLQVSLNETHLISGVQMQGRYSNGLGQEYTEEFQLEYWREGFQSWRKYYRFDGKTVFPGNTDTSTVVTTKLRPPLFAQKVRFLPYAAHRRVVCLRVELLGCVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMY3</accession>
    <name>A0A1D2NMY3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMY3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905767" evidence="2">
        <location>
            <begin position="19"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="8108" checksum="2F9DA3671C29D4D3" modified="2016-11-30" version="1">MKIALFLLISAMVVLAYAQEEVVFEDEILQESTEPSSSTEAASSETVPGSTTEAGAYGLKSNLGVLAIVVASIFLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNW1</accession>
    <name>A0A1D2NNW1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Trehalase</fullName>
            <ecNumber evidence="3 7">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_00022</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="3 7"/>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NNW1"/>
    <dbReference type="STRING" id="48709.A0A1D2NNW1"/>
    <dbReference type="OMA" id="DAPFGWA"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF1">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905799" description="Trehalase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN06626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="616" mass="70290" checksum="188B775733955264" modified="2016-11-30" version="1">MTSQKIVSVACVLLASLFLCCKGQIEFGKPCSDDIYPQSQIYCHGDFLLTIQKAKLYPDQKTFVDRPLKANATEVLEKFDELGIVGDNLNDTARQTIAEFVDEYFDRNGTEFEAWEPTDWVENPSFLEGINSTDLRQWASDLHKFWKELGRKIRDDVKTNQHRQSMYYVSHPVIVPGGRFKEFYYWDSYWIQRGLLVSNMTQTVKGMIENFFEMVEQLGFIPNGGRIYYQRSQPPLLLPMVDAYFEATKDEEFIKANIGTMIKEFKFFLDNRTVDVYSNATGATHKMARYNVELTDPRPESFSEDYELVHSLDPDNQTAKDLLYANLKSGAESGWDFSSRWFVLPDGESPMQGNLTHTKTRDIIPVDLNSFIYWNAMLLTKFCGLINDNNVCNPSEYLQHANNWKDAIDDVLWDEEDGIWYDYDFVRHQKRKFFFPTNVAPLWVNATNGLTKDVAKQVVHYLHTSGATNFPGGIPTSMLQTGQQWDFPNGWAPLNHLVVEALEYTGEPTAQDLAFNLAQKWIQSNHLAYVQTEAMFEKYDVSIVGSAGSGGEYEVVVGFGWSNGVVLDFLKKYGLRLVPVDNLPSTTPADSFAVRVNAMNTVVIISSIVLVLKQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M186</accession>
    <name>A0A1D2M186_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007536">
        <property type="protein sequence ID" value="ODM86712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M186"/>
    <dbReference type="OMA" id="EYINRTQ"/>
    <dbReference type="OrthoDB" id="6755924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12829" checksum="5CC5682ED52E9C62" modified="2016-11-30" version="1">MEFRPEGVYFPTVHLRKTSRPNHLPVAFYGAFYGNPKLCVVTTLKEYINRTQFLRGSTRLVISYVKPHKPVTPSTISRWICNVIHAAGVPLSYGAHSSRSAATTAAKFCTHMYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M233</accession>
    <name>A0A1D2M233_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006373">
        <property type="protein sequence ID" value="ODM87029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M233"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="60" mass="6656" checksum="6B17370BF9159FBC" modified="2016-11-30" version="1">MMGAAKLKKIGMSKNPMASRRRISNGTENLGFELDEKDRLPPLSDTSYGSTKQNQKKVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2A5</accession>
    <name>A0A1D2M2A5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized transposon-derived protein F54H12.3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006165">
        <property type="protein sequence ID" value="ODM87099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2A5"/>
    <dbReference type="STRING" id="48709.A0A1D2M2A5"/>
    <dbReference type="OMA" id="RYFTHTQ"/>
    <dbReference type="OrthoDB" id="6343797at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585:SF1">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585">
        <property type="entry name" value="INTEGRASE CORE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="65"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="213" mass="24751" checksum="9DEC5F0020509800" modified="2016-11-30" version="1" fragment="single">MDQDNEKILKSYFNPSSSGSFGGIDRLKQIHQTIPASKIKEALQTSSTYTKHKRVLHTFLRRKVNVHTSNYLWQADLIILNKYAKQNKNFKYLLTVIDVFSKKAYVAAIKNKTGLDVTDAFSTILKQANKKPTYLSSDLGKEFFNKTFKTFLDINKIELFAVHSDKKACVVERFNRTLMERIQKYFDHSGKTKYIDVLQDIVHSYNESLHRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2L8</accession>
    <name>A0A1D2M2L8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dual-specificity kinase</fullName>
            <ecNumber evidence="2">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_19488</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01005929">
        <property type="protein sequence ID" value="ODM87194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2L8"/>
    <dbReference type="STRING" id="48709.A0A1D2M2L8"/>
    <dbReference type="OMA" id="RDHKENR"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.30">
        <property type="entry name" value="DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042521">
        <property type="entry name" value="DYRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="56"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="348"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM87194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="400" mass="45634" checksum="E06F1FF41C411459" modified="2016-11-30" version="1">MAEGLSEKMDVSQEVEEAVEQPSPSEVESVKSGMTPQEAYEKYQFDLSSFETSEIFKYPEIYFVGENATKISGGRSLSDTSIFDTKRNNCSSFLRRDHKENRSVAIKVMKSQPRYHQQAKPEIEMLERLNKLSKAENIDVVQMYDHFEFRNHVCIVFELLSKSLRNIIDETREQGLPLHRVQEFAASIIKVLDALGRNKIMHGDLKTDNILLKQPGTSDIKLVDFGIAEYDREEQTELIQALHFRAPEVGARSGMTDQLALAMEVFGVPPPEFLKVCSRAKNFFKDGKPYVADFRSYAEYRGKAGSRNLSLVLKNCKDVHFQDFIRGCFTWDPKARLTPSQALVHPFLTNKLPNPDDTEESAFAPAAEDSQPDSPASRRTYEESRATNKRKRSGWKIDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M356</accession>
    <name>A0A1D2M356_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_19282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005406">
        <property type="protein sequence ID" value="ODM87399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M356"/>
    <dbReference type="STRING" id="48709.A0A1D2M356"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="3">
        <location>
            <begin position="134"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM87399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="29539" checksum="BDF2384637411C87" modified="2016-11-30" version="1">MFSNPTEINGRWKLLMYYSIKFFAPVLASPYLNRNGDLVVELISDSGRNFSGNLTVQIFGLKSLTPLFEQNVKVKAQFLTSKEVFRVNKTALQELNCGTTAKAGSLNPCVVYLTLPGTPDNFLFLQYPTNKLALRNPNLQITLVEAVNTKTVNFTVTTDAIAPFVFFTVRGDHRGYFSDNGFVLVTQERKMNYYSESGITPQQFMDRLQVMSLYDVTKVAGSQVGVNSNMQLHRARSLQHYYRSSDENSVHLSHWLRDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M399</accession>
    <name>A0A1D2M399_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exocyst complex component 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005383">
        <property type="protein sequence ID" value="ODM87412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M399"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="66" mass="8082" checksum="3BB6AB2C0141EC21" modified="2016-11-30" version="1">MQRTDISADLNHLTGRLPKKWKNHAFEILEYRSVTWNDWKSWPIGVRDENKMWLVRYLEVMRPTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3I9</accession>
    <name>A0A1D2M3I9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TBC1 domain family member 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005100">
        <property type="protein sequence ID" value="ODM87529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3I9"/>
    <dbReference type="STRING" id="48709.A0A1D2M3I9"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="12959" checksum="19A573718BD986DC" modified="2016-11-30" version="1">MVLKQAYIVNHENLKKERQIQSCDHCPMVWYRQLCNEVMVRIPCDEKIKACILKYINGLPDEDRQNILAKFHGAEPQTVQEQNELLMMLLRAHCESKQAKHIHDTAENRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M456</accession>
    <name>A0A1D2M456_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein boule</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_18926</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004726">
        <property type="protein sequence ID" value="ODM87759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M456"/>
    <dbReference type="STRING" id="48709.A0A1D2M456"/>
    <dbReference type="OrthoDB" id="762982at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008494">
        <property type="term" value="F:translation activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070935">
        <property type="term" value="P:3'-UTR-mediated mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11176">
        <property type="entry name" value="BOULE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11176:SF57">
        <property type="entry name" value="PROTEIN BOULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM87759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="194" mass="21600" checksum="90A21A5214AB441E" modified="2016-11-30" version="1">MQLSWTKIILDRAGVSKGYGFVTFETEEEAKRLCTSIVEPIIHRDRRLNIAPASKEVDALSPPPPYDGTSVYFPQTAQATQFYAQPTPLPEPFFAQTAAFCPGPTINFTSFVLLFYYSPTSVLSLAHNHWPTPPPAGAMNGNAKRKWAVSMEVGFSRCNPNEPINSTPHRSLRSCITHVRTVTAKCINHHFSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4K3</accession>
    <name>A0A1D2M4K3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004425">
        <property type="protein sequence ID" value="ODM87903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4K3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903460" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="57" mass="7014" checksum="976BF541D8B478CB" modified="2016-11-30" version="1">MFFQKNFHIFMFVLTVSMLLAETLCQPTEYQDYGPQSEMREKRFFHHIANWFGQHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4V7</accession>
    <name>A0A1D2M4V7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004268">
        <property type="protein sequence ID" value="ODM88005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4V7"/>
    <dbReference type="OrthoDB" id="8289735at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903467" evidence="1">
        <location>
            <begin position="22"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="23781" checksum="1C111D728C5C4945" modified="2016-11-30" version="1">MKSLFFPIAIFVTAFISSIQCLDLESAKEQPCFKIKKTVPLITDDWVQPEPKAIYYPLMSRLDLYRNAIDLLQKDPAEISESELYYDACIVWKCNNETYFSEGFGGRTREYTADPEDDKMEVYTMRPLKGKGYGGKAFTTYSDNETFFFTAVCGDDGQMAWNVASLTPTLPRESVKIIHEHALSLGFKKEFFTELRYDRCHFQNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M564</accession>
    <name>A0A1D2M564_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004111">
        <property type="protein sequence ID" value="ODM88103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M564"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="87" mass="9559" checksum="204FF92AE17411EF" modified="2016-11-30" version="1">MADSSGTPPESPRRTNPSGSIGLIDDSRLSLAASRVVAKAIQHVATNNDREAVNNSERNSVKQNAEDDTRQPEKPLWPKSRCKWMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5H6</accession>
    <name>A0A1D2M5H6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative 4-coumarate--CoA ligase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003922">
        <property type="protein sequence ID" value="ODM88240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5H6"/>
    <dbReference type="STRING" id="48709.A0A1D2M5H6"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="23814" checksum="B2600771FE7D8CBE" modified="2016-11-30" version="1">MAYERITIELIVCEEDAWNYVKGADKLEGCKNHNSNRSNSSSLQQFLEEEMDQPGFIFAFPTFLTGNDLPNFSVGETIPWTLIQIRNPETLESWPDQRGEICVKAPEETEKAFVDGFFRTGDIGNYDANECYWKTSAAERSIVVVAPDVGGHVPRAFVTVHQSSDAKKDVEEEIKEYANAKLASYKHLRGAYTLLMNYARKNWKNITIAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5K3</accession>
    <name>A0A1D2M5K3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ceramide synthase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_18492</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003985">
        <property type="protein sequence ID" value="ODM88192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5K3"/>
    <dbReference type="STRING" id="48709.A0A1D2M5K3"/>
    <dbReference type="OMA" id="MIALNCA"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM88192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="12289" checksum="35197DD6E72AEAE7" modified="2016-11-30" version="1">MSKYANNERLAEKIFAVFILLWIITRLGLYPFYVLHGIFFEAPKITNTAFPAFWLFSVLLLLLQFLHIFWTYYIIKIVLDIVLSGKVRMHLKRCKMIECVIMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5P9</accession>
    <name>A0A1D2M5P9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Low-density lipoprotein receptor-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_18383</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003808">
        <property type="protein sequence ID" value="ODM88298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5P9"/>
    <dbReference type="STRING" id="48709.A0A1D2M5P9"/>
    <dbReference type="OMA" id="HANCEDG"/>
    <dbReference type="OrthoDB" id="9990982at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042562">
        <property type="term" value="F:hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000065">
        <property type="entry name" value="Transmembrane protease serine 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF14">
        <property type="entry name" value="MEGALIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903500" evidence="10">
        <location>
            <begin position="20"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM88298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="277" mass="29968" checksum="5E4A289907842649" modified="2016-11-30" version="1">MKFSLVVLGLSAVLGIAYSQDCEGNEFLCEATNVCIPASRVCDGIADCVGASDEVDCPSTTTTRCPGFECTSGSCIPESWICDGDNDCGDMSDEENCPTRTTTPCPGFTCPESGRCLPASWICDGDNDCGDMSDEQNCPSTTTTPCPGFVCPESGRCIPASYVCDGDNDCGDFSDESEEACPCADNEIRCEKPPGSEVPGACIPPEYICDEDGIWDCPDGSDEANCTTAFNPANPHFRLETIEAQKLHHMMKENHRQVLGEEIKEKQYLKKRSNKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7V5</accession>
    <name>A0A1D2M7V5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002977">
        <property type="protein sequence ID" value="ODM89011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7V5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="454" mass="52498" checksum="3F8A70CE392C69A4" modified="2016-11-30" version="1">MDKAGVVTPAPLEPAEIMASYDEFPAGGLPEVWLNVLNKLDQKDKLAVSGASAVWHDWMEPERTQFLISEVTPYLVEPHRPVDTKRGHRARELCQSWKEGLDHQNQTHGSNTNLYFEMASCEDPHQWYPCRRSLLCGTLLIFLDDVQRFMEDMKSHPENPFPGRSIHLCCSFQEDNDPLGEAWDGVWREYWSNTYLLLEKFGSHVHFADIMFNEDEEYEQLHLDDMEVQARLRGCLLRLPNIKQLHTCSENKTPLLEEEISEYYRRNPLPRLEDLETVELQYMSLATINEVLNSCCVPTNIKRLSYRHIGLDYQERLTLCDAVYGFTNLEVLSTSILLCHLERLARLEQRPPLREVDLRFREAPYLQEVLSLLEAFAGTLIQFKASSTMRVRMNEENERGIQLQTAKLEETSLCGVLGTPELLFQFESVTHLANIQMRGSNGEKIGSQFREADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8L7</accession>
    <name>A0A1D2M8L7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 1A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_17359</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002720">
        <property type="protein sequence ID" value="ODM89327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8L7"/>
    <dbReference type="STRING" id="48709.A0A1D2M8L7"/>
    <dbReference type="OMA" id="MMADDEY"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903612" evidence="10">
        <location>
            <begin position="23"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM89327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="22304" checksum="95F23083CDD7CE30" modified="2016-11-30" version="1">MFYFSSSTLSFATLYLIHNSEAQRNAQQKIDRVVGCRKISLSDRVLLPYTEADYSGNFATSSITPLGVPHQMLADTVFQGYFLPKGATVVTNAYGIHHDPKIWGNDVNEFRPERFLSDDKKRVIRHYALIPFSVGRRSCIGEGFARDVIFLFLASILQKFNIKPDPDCPIVDIKPMSGVALEPKPFNFVLNLREKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9M8</accession>
    <name>A0A1D2M9M8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3/1,6-mannosyltransferase ALG2</fullName>
            <ecNumber evidence="10">2.4.1.132</ecNumber>
            <ecNumber evidence="10">2.4.1.257</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_16998</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="EC" id="2.4.1.132"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8 10">
            <dbReference type="Rhea" id="RHEA:29516"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29519"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="EC" id="2.4.1.257"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9 10">
            <dbReference type="Rhea" id="RHEA:29520"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.132" evidence="10"/>
    <dbReference type="EC" id="2.4.1.257" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01002446">
        <property type="protein sequence ID" value="ODM89685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9M8"/>
    <dbReference type="STRING" id="48709.A0A1D2M9M8"/>
    <dbReference type="OMA" id="TPSIYYC"/>
    <dbReference type="OrthoDB" id="448893at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004378">
        <property type="term" value="F:GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102704">
        <property type="term" value="F:GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03805">
        <property type="entry name" value="GT4_ALG2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027054">
        <property type="entry name" value="ALG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918">
        <property type="entry name" value="ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918:SF1">
        <property type="entry name" value="ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="12">
        <location>
            <begin position="25"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="11">
        <location>
            <begin position="222"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM89685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="433" mass="48375" checksum="803686CA7951D014" modified="2016-11-30" version="1">MSEANDVPVSEKGRVAFIHPDLGLGGAERLIVDAAVGLKRRGYEVTIYTGYHNPSHAFPETVDGTLKVVPVCQWLPRTLFGRCIALCSYVKMTFVALYISLLAVFSSSSRRPQVIVCDQVSACIPALKLTPFLFSPRIMFYCHFPDLLQTSRSSLFKRVYRAPLDFVEELTTGLSDKIVVNSLFTKSVFQETFTRLRSNIPDVLYPSINTKLFDEAMKSKSAQKEVAELKLKKYTFLSVNRFERKKNLALAIRTLRKLGTCVDADEMKKVQLVLAGGYDSRLEDSVKYLEELKQICKEEGVVDQVKFVLSPKDDVKVQLISKCVALLYTPSNEHFGIVPLEAMYMGKPVLAVDSGGPRETVVHEVTGFLCPSNEIHFAAAMATLITEPEIKESMGNAGKARFKDKFSFDAFSKMWDQSIEKLISGPNTATKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9N5</accession>
    <name>A0A1D2M9N5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Caspase-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002480">
        <property type="protein sequence ID" value="ODM89651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9N5"/>
    <dbReference type="STRING" id="48709.A0A1D2M9N5"/>
    <dbReference type="OMA" id="ALMENAH"/>
    <dbReference type="OrthoDB" id="6097640at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01671">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002138">
        <property type="entry name" value="Pept_C14_p10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901">
        <property type="entry name" value="CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901:SF8">
        <property type="entry name" value="CASPASE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00376">
        <property type="entry name" value="IL1BCENZYME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50207">
        <property type="entry name" value="CASPASE_P10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Caspase family p20" evidence="9">
        <location>
            <begin position="150"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Caspase family p10" evidence="8">
        <location>
            <begin position="321"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="404" mass="46580" checksum="CE064E1E28207C8F" modified="2016-11-30" version="1">MKDWERKCITTNKSALCDAINLKDGKILAALETAEILTEDESDLVSMHLPLRIKANNEMLNLLMKRTKGYEELMKILADLKQDKAYNILKTCKEKCEPKDNKEQQESVAKQIKSLEDEVDGPDPIKKVVVKRPDKHMNFEKDYYRLPVKGKGLVLLINVIIFNRLCRKKTKQLVDIKPRASARRDTENLISLFSEIGYEIYKKDIILKKEVWTANEIKAFVEKFKAHCNQTDVASTVVFVGSHGKDGMIFGSDWKPVFIKKDIVNKYNTENCEKLLNKPKIFIIQACQRFEDENDEDDDMHGDEDDEPYTPNFDNYGVVKATISGFPAKRNTDVGSILVHFLTKALMENAHYLPFKKIIKLVNDNVKQYEYEPLEAGKFQGGQVIEADLLQLKKLYFNLEPEYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBY7</accession>
    <name>A0A1D2MBY7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">POU domain, class 2, transcription factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16255</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001975">
        <property type="protein sequence ID" value="ODM90432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBY7"/>
    <dbReference type="STRING" id="48709.A0A1D2MBY7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013847">
        <property type="entry name" value="POU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000327">
        <property type="entry name" value="POU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050255">
        <property type="entry name" value="POU_domain_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636">
        <property type="entry name" value="POU DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636:SF76">
        <property type="entry name" value="PROTEIN NUBBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00157">
        <property type="entry name" value="Pou"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00028">
        <property type="entry name" value="POUDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00352">
        <property type="entry name" value="POU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51179">
        <property type="entry name" value="POU_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POU-specific" evidence="8">
        <location>
            <begin position="6"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="92"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM90432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="17413" checksum="48FBBB030DB09CE5" modified="2016-11-30" version="1">MQSPIDENTRLEELEEFIINFRMRRLKLVGKLYGKALSQPTNFPIEVLNLSYYKMCNLQSLLQKWLEETEDSLKHSSDLTGLYPLTTCQPIERGRCRRTIISPSERDNLTRAFQHNPKPTSEEFVISLRDLEWRRKFVRIWFYNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC52</accession>
    <name>A0A1D2MC52_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Heat shock 70 kDa protein cognate 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_16162</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001923">
        <property type="protein sequence ID" value="ODM90519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC52"/>
    <dbReference type="STRING" id="48709.A0A1D2MC52"/>
    <dbReference type="OrthoDB" id="360839at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000545">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0346">Stress response</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="780"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="818"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 1 N-terminal" evidence="12">
        <location>
            <begin position="42"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="11">
        <location>
            <begin position="779"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM90519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="910" mass="103157" checksum="A87EC124766743D8" modified="2016-11-30" version="1">MGIGEQITQFESIPPISIYWTIIVCIWVEYLFEPDGYITSANKLPTPLKDHMTLKSFEKARVYGIDKNNVSIVSEFYRKVVLTALLHYEGLYKGWVLTGPMLSGFGTGQPPGMLRLGEHLLQYSRHAVQQHGESIVNLLHLRPRGTTRLQQPNLWLLCQGLYQEDHRQRHHHLPNCRSDCQNRPGRRSILFRVAVSLFASSSFMVTFETTHHIAAFTAEGGGWLGTPLRISSRRTPRRPREWEDPTVQSDIKLFPFRVVEKNSKPHITVSTVQGEKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIADSIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGSWSGYGLLHQALQEEEGQDNRAVQKLRREVEKAKRALSSAIRPGSRLRGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDADMKKKDVDEIVLVGGSSRIPKIQQLVKREGAFQGINPDEAVAYGAAVKLNRLTPDDIERIIKVWLMDYYVFSSVRNCFCNVFDAEKFSDDDEKVKECVESRNELESYAYSLKNQIGDKDKLGAKLSNNDKAKLEEAVDESIKWLESNADAIAQSLRNKRNSLTTSHNQSSPNFINKGDLGQTLEQRLKIRTNSSAILRVFSWSPPLRSRIEALAAASSSTDQTLRGGLQEVCTFQRLYFMDSSTNKRIVLYDTLINGTCQKQRTRRRTKIRTRIKPSKRTRKRRKRRRTKRREGIRFGTLEAEPRGENIIISQANIFVIFCLFAFFYRNSALYEAFGFPKQSDMLILLGLIIVLQFLLQIINTAMGYLMNVLSRLFEFQADAYAIELGYGKFLKTSLIKLNNDNLGFPISDALYSAWHHSHPTLLQRLSAIDLLMTKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCK1</accession>
    <name>A0A1D2MCK1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001873">
        <property type="protein sequence ID" value="ODM90631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCK1"/>
    <dbReference type="OMA" id="SQATHIG"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="69"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="27668" checksum="0E7A59D23CE2398E" modified="2016-11-30" version="1">MVGVIADLEEAGLLRQFKEAVVDLKQEDIVLLRFLRARNHDLNKAEEMIRYAMQWRQEIGIDNYMKWEFPEYYQTEMAYKFFGKCRENPNLWVFVGKWNGKTLVDNGEGENLLLWALAMIEQGMRVVHDTKKQGNVIIDLQGLTYSQATHIGSLKLFYQGCQKIEQCYPEIIKSVTIINAPWVFTLGFNFIKGIITRKTMEKIKIIGCNKNEWMAELQRKLPNSSIVPELAPRDENGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCX5</accession>
    <name>A0A1D2MCX5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine/tyrosine-interacting protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15825</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001766">
        <property type="protein sequence ID" value="ODM90856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCX5"/>
    <dbReference type="STRING" id="48709.A0A1D2MCX5"/>
    <dbReference type="OrthoDB" id="426001at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14522">
        <property type="entry name" value="DSP_STYX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000036">
        <property type="entry name" value="Serine/threonine/tyrosine-interacting protein a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="83"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="151"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="280"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="319" mass="35369" checksum="628CE05F61975074" modified="2016-11-30" version="1">MNYEEVVVHDGMHETMDDEVEVIFEEEMEDCPILEGGDFGIPHPLGLGTDRKVLVKKERYVEPDYPRLPSEGNLEWQYTMRRTMQEIIPGLFLGPYASATRAKLEEMKAAGLTHIVCVRQNLERNLIRPNHPDHFKYLVVEIADSATENIIPHFKVVNSFLDECLSGGGKVLVHGNAGISRSAALVIAYIMSKFGVTLKEAFSFVQSKRFCCNPNEGFMAQLREYEPIYRALHTVPLPLPGVNPNRASMKRGLDPEDAETNAAAPPPVMDNRQFDSGHTSQSASSESSMSSSSESLPQVGAPQFTPPTNQSTDTPMSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD21</accession>
    <name>A0A1D2MD21_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001755">
        <property type="protein sequence ID" value="ODM90898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD21"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="693"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="943" mass="103440" checksum="31626AA330FBB66C" modified="2016-11-30" version="1">MADDELSDSPAARRGPVLTPLLPPPPQIMIIERQVPSSTATFTTTTGGLTTADTYSPPFTSQSLGPTTATEEEDEKVEDNSESLTVQDEEDDGKTSEKEESKLETEVDEEKEKEDATELEFSEGADIAEKKGESVPPPLPPQVEQIEEKISEAEAVANSPIPTPLSPIEKEEQTENHNDLTPDSKEEKEKPEEKIDTELKEEFPPLSQTSSATQSSQTQTPVSNLDDHGTQTIRFDSSSGGPVSDEERTAGATASHPSSAGGAPPSSAKKRCRPFCVITTPPPPSKINSGTVTTAVPKLSRIIEVQSEQLEHNKAVDDQMAYKTILVPGMIPERLRKLTKRRKKKKGEEEVQDQNQNRVERTISLSKLSEKVCQEIVDETSGQPQVESEKGRPCTSQKIWEQAAMQFQAKVGRYVEQKRRRKSTTDVKLFQELNDEINSNPPEAAENSVKESRSVPNAITEEVSERLKSILKRGTPKKSGKLVNSLLWLRDAEPAPPQFKGRTLPHVASATFDHEILAELKRRLQMLKYQQEDTKIGKLMSSWALTSLDTQLPQLNLQDMMIQPPTVFPEKGEVKHEEKPLPPPVSSPEKRPAAVTKSTPIVPSQMTTTSSFIIAGAPSGIKRNKSHHHLLFKKSIQKVPPPVPPQSPKKRMRKQPIYIAPSMKIPTFTIGPPPKGKGKQAKNSKSKAKIQKTSGPTTPTTATTSKPSSTSTSTRIFVKAKVGKTKITKSPVRASISGFKPRAKSTNSTTTVIQTLTSNRRREMNLADRNTIKKVIFVPTSPSSKLFRSNLRKLSIISKKLDADNSRRGGTGQKGKMNEKKTGSTTTLFRKSEGGKQSLKIVPETVEPVFVGGARPTKKVGGGVGLNSNTKGKSVMNFQLSEADREKLARRVSFSDPIAIVKTVSPTDLNENSAAVQLENMSLVIGPGRNSPRRETKSQFSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDP9</accession>
    <name>A0A1D2MDP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Guanine nucleotide exchange factor MSS4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15577</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001669">
        <property type="protein sequence ID" value="ODM91110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDP9"/>
    <dbReference type="STRING" id="48709.A0A1D2MDP9"/>
    <dbReference type="OMA" id="VPLMMQK"/>
    <dbReference type="OrthoDB" id="30840at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.10:FF:000005">
        <property type="entry name" value="Guanine nucleotide exchange factor MSS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.10">
        <property type="entry name" value="Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007515">
        <property type="entry name" value="Mss4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011323">
        <property type="entry name" value="Mss4/transl-control_tumour"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13276">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13276:SF0">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04421">
        <property type="entry name" value="Mss4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51796">
        <property type="entry name" value="MSS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="122" mass="13782" checksum="41CAA0599F083908" modified="2016-11-30" version="1">MATSSSDNVDVKDPVEDGKNKYTLVCTLCPSKILTPLSGEYLKEERQLPKMSQKKNSPEVETDTIQEWFLVDNMFTFENVGVSYVVDNMKFLTCADCESGPIGWMDITSQKSYVALPRVRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME35</accession>
    <name>A0A1D2ME35_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase [acceptor]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001660">
        <property type="protein sequence ID" value="ODM91131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME35"/>
    <dbReference type="STRING" id="48709.A0A1D2ME35"/>
    <dbReference type="OMA" id="CESHAPD"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="33"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="176" mass="19478" checksum="59B4236C721C6778" modified="2016-11-30" version="1">MFGLRADLLDSWFDPFHKNNTDARFGLMWIGRPKSVGNVTLASTNPADNPIIDPQYLAHPDDMEALLYGYKKYVDLFENSSLNTPLYYKPVPGCESLEFKSDDYYRCVIRSLTGTVYHHVGSCALGKVVDNSLKVIGIDGLRVIDASVMPRLPNGNTQAATIMLGEKGSDLVIADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEB2</accession>
    <name>A0A1D2MEB2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001589">
        <property type="protein sequence ID" value="ODM91340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEB2"/>
    <dbReference type="OrthoDB" id="431169at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="65"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM91340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="15561" checksum="C36AD71B607E029F" modified="2016-11-30" version="1">MSQRPGRNGRINAGRRSKGSGQVPVEHNARSRGKKPMFPAFAPSQCDLTDRYKSQGNSSDLYENNQLYVSNLPPETNMEEVSRVFPDCVSIRLGVNNSNEQLAAYLEFPDPITTERASNQARGACIRGQYLIVSPKLKCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MES0</accession>
    <name>A0A1D2MES0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glutamate receptor ionotropic, kainate 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15164</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001525">
        <property type="protein sequence ID" value="ODM91517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MES0"/>
    <dbReference type="STRING" id="48709.A0A1D2MES0"/>
    <dbReference type="OMA" id="FTERDCD"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000061">
        <property type="entry name" value="Glutamate receptor, ionotropic kainate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="17992" checksum="25640CFDD903315E" modified="2016-11-30" version="1">MWGYMESRPNVFVQTYEQGIKRVLQGNYAFLIESPMLDYVVQRDCNLTQIGGLLDSKGYGIGMPKGSPWRDKLSLAILELQEKGIIQLLYNKWWKNTGDVCNRDDKKDSKASPLGIDNIGGVFVVLVAGLVLAVFVAICEFCCHVRRNASLRKVSHCFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEV0</accession>
    <name>A0A1D2MEV0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15176</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001528">
        <property type="protein sequence ID" value="ODM91505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEV0"/>
    <dbReference type="STRING" id="48709.A0A1D2MEV0"/>
    <dbReference type="OrthoDB" id="6596655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="333"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1016"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1131" mass="129348" checksum="6DB8C54905FD9FAD" modified="2016-11-30" version="1">MKDYIQWIHACVRENLYELLKVIIKFGENQEVFETEDILLLALKFADLPIIKLVVKHYAQQSLKNLKDIKLELKWTGDDKEMEIITMLHVAALRGNYSVMQYLLKIHGFEDLVKQQHICEILCFCVVGTYTKDEEIHERKRIINDLLNINPSLIEGVNKLRFTPLLYPNIHFDLVILLIDLGVNVDATNFISNNMLHLFPEYFTPEEYDKVVHHLENSGKTKLFHSLNKRQETPLYRAILYFDLLDSTIDIFARAGFDFNVPIENTTTLLSHAIEEERSARLLDSLVRSGADINKRVGKYVMTPLHKAVSQDNLSALRYLISRGVDVNAVDNDKETPLHLALRLPGRYSYRIVQSLLQHDADINAVDTLNRTPISNAEESYKNGKISKQTLELLEKRLPKQAQVVKEDVITLSKSKTITIDGTSYIAETLFINLEKISQVFIENAITSWDECRIVKFNIGHKVDRSKCVSRNSQNLCTRFPSCTCKNEEIMVEFNFKFVKCNHKRLNVSVSIHELLPVLRDILNLNDSLKLFEVKRLFRQVYHLPYNIDILRIMEKPNDAQVLSHISQGNYLLGELLSSLGNSESERNQLKHIAVNTLFPNFTRNIDVKGFDDYLKSGILKYDGKLVFTNSDLAWCLISELLLNFEKSEFADLRLNGMLSSIFNDCVDCKKLVIWHSIGLAAEEMETFTFKNHIFFNSLEHLLSKKNSENSLRTILNKNLTKDNVDKCLQASVIANLPNLLRILLSTLGQTKLFESRHFVGLAVKFSGFQIMELVIEQYIRQTDNQIKHAKLSVSDPYYVIPVLHIAALRGDFSVMRYLLEKHAFKDRLHYSKLDNILHHCVIHTCKFQGNDVIERQRIIRLLVELHPQLIHKKDKFNRTPLMVPYANVELIILLINLGVDVSATNNQSKNVLHICAEYLDPQGYDKLLRCLSNRGDTKIFHPQDSFQETPLSRAVTCLDALDSSLKLFSTINVDFNAENSYKNTVLVLATLFHRSSQLLDSLIRFGADIDKRGFSDRTALHSAAEVGNLNGLKYFISKGCDVNAKDKDDSAPLHLAVKYSKINTHEIIEVLITQGADVNALDNEGDSGHTPLHTAFQGESTVHDVVTELLKHGCRYPIATDKDENYQVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGN1</accession>
    <name>A0A1D2MGN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_14516</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001308">
        <property type="protein sequence ID" value="ODM92166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGN1"/>
    <dbReference type="STRING" id="48709.A0A1D2MGN1"/>
    <dbReference type="OMA" id="PGMETIC"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="8">
        <location>
            <begin position="105"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM92166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="442" mass="49707" checksum="7C8C23DD30F7FDF3" modified="2016-11-30" version="1">MHSPVEFPTSRNKLHMERNGLRRKCAAYKPPSIDPILLFGSAECRNSVKWSLRLPKVVEKLPLITELQSKGFVASTHTILSKDGYYTTSTRISGSESSPPKRGKPAVLLFHGMGSRGESWTIQPGNRNLAFMLINAGYEVWLANLRGSTPSQNHTHLNYKRNLLFWNFSFEEQGTLDLPPLVDLILKETDTEKIYFVCHSSGCSSYLAGLAEIPELNKKFKAGFLLAPSSFLGSAYGPAAKLRVLSGTSWEQILFVLLRGRRNGGQSDLAKALGFPGMETICSISALQCGLCDRFIFAMFGADVKQLNFTNIPNMIAKSQDNTVWKSLVHTGQNLMSCGFNKFDYGSRRNLVEYGSQYPPKYDLEKVAVPTYIFYGESDNLITPWDAERTKQAIPSKYMKGFYRVDWPLFNHIDFLMANDADILVYKKILTIMDELEIKNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGZ6</accession>
    <name>A0A1D2MGZ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001277">
        <property type="protein sequence ID" value="ODM92286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGZ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MGZ6"/>
    <dbReference type="OMA" id="EDYPWPM"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF227">
        <property type="entry name" value="GLUCOSE DEHYDROGENASE [FAD, QUINONE]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904022" evidence="4">
        <location>
            <begin position="22"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="612" mass="67787" checksum="F8EB469599BAF22D" modified="2016-11-30" version="1">MPLLSVFAVLLGIWLLPIPLAYIGYEVYEFNDPEGRPFVELDPLPIYDFIVVGAGSAGAVVASRLSENPAWNVLLLEAGGDEPEIVSNAPALAANLQMTRIDWGYRTEPMTTACLGLEGSRSKWPRGKVLGGSSVLNYMLYVRGNRRDYDRWESFGNPEWGYDDLLYYFKKSEDNRNPYLARTPYHAAGGYLTVQEAPWRTPLATAFVQAGIEIGYENRDINGESQTGFMIAQGTIRRGSRCSTSRAFLRPIRHRPNLHIVIHAHVLKVNIDHVYKRAWSVTMLHQGRMRIIQARNEIILSAGAVSSPHILMLSGVGPAEHLTELGIPVIQDAAVGLNLQDHIGFGGLAFRVDQPITLVQSRYEDMVSAFRYYVNGEGPMTVLGGVETLAFVHSKYSNVSLDWPDVQFHLIPATIGSDGGQTIRRALGVSNFLWETVYKELSFTDSFSAIPVLLRPKSKGYIKLRSAHPFIPPIIVPNYLTEPEDAAILVEGAKLGLALSQTSALRRFGARLHDTPYPQCVHLGLFTDEYWECCARHYTSTIYHPCGTAKMGNATDPDAVVDPRLRVYGVHSLRVVDASIMPTIVSGNTNAPCIMIGEKAADIIKQDWGFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH90</accession>
    <name>A0A1D2MH90_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative chitinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14307</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001249">
        <property type="protein sequence ID" value="ODM92377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH90"/>
    <dbReference type="STRING" id="48709.A0A1D2MH90"/>
    <dbReference type="OMA" id="KMITFTY"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF403">
        <property type="entry name" value="CHITINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904023" evidence="5">
        <location>
            <begin position="31"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="49"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="234" mass="26273" checksum="89292159D0899108" modified="2016-11-30" version="1">MDSFKFGKTLHVLAVVTLATFAVCSGKANATSIENDRGTLEEKDAAENPVLVCYWGTWSHYRGGNGQFRVENIDPFLCTHLVYTFFLLDETTSTVKYADPWLDLPPPPAYPDGGLDNIRNTINLRNTNPDLKITMAIGGWTEGSTKYSDMAKDPRKRRAFILSIISMIRLWDFDGIDMDWEYPARRGGLAEDKQNFVLLLKELREELDKVNRPGKDPLLLTSAFGCGQDTIEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHM3</accession>
    <name>A0A1D2MHM3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001241">
        <property type="protein sequence ID" value="ODM92402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHM3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="214" mass="24335" checksum="B0331D332A0855AC" modified="2016-11-30" version="1">MADSASGHQNEGLATKKEMLAVNKPEDTSKPSRTQMRSCKSAKQDKKRDGNSNNKPVKQRKNVLNREPKIKFGPPKRLRRDRKPESPDFKIEIVPFNEDEDVGSSDGVPLVAIDSIVEQLKPLKFYCHRCERFFTRKCHLVNHLKSHVKCGELPEYEVDNLVSLGSIAKIQLWKYAADISSEGQQDAIVTCFSTLKQGGFFQFTFRRPEAILLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHS9</accession>
    <name>A0A1D2MHS9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01001218">
        <property type="protein sequence ID" value="ODM92481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHS9"/>
    <dbReference type="STRING" id="48709.A0A1D2MHS9"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000596">
        <property type="entry name" value="CK1 family protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="11"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="35508" checksum="CA0666DF0E551CDC" modified="2016-11-30" version="1">MSVELIAGGKYRLVQKIGSGSFGDIYLGINVTNGEEVAVKLEAVTDRSPLLLNESQLYKILQGGIGIARVRWCGMERDHYVLVMDMLGPSIEDLFNFCARKFTVKTVLMLADQMIGRLEYVHTKSVIHRDLKPENFLMGIGRHRDKVYIIDFGLSKKYRDPRTLHHISYKEEKPFIGTANYASLNAHHGNELGRRDDMESLGYVLVYLLRGALPWSQLKAATKKQKYEKITEQKMSTPAEQLCKGYPAEFSVYLSYCRNLRFEEVPDYTYLQQLFRILFRALGYQYDYVFDWILLKDKAAQVSTAVRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIX0</accession>
    <name>A0A1D2MIX0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001115">
        <property type="protein sequence ID" value="ODM92939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIX0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="577" mass="64783" checksum="5D96C697D0D0ED1D" modified="2016-11-30" version="1">MKLALAIPTPQDAREHRQVEVDVSQPEQTTSTETPQVETTTIKNFLSYLFQREGNRDPWLAQLVKATAPVLAEEGFGGVVRQSFKIAPVSPWPEKVPLTLPRRQQAYPNLPSSASNHPTPSSPLTELHRSEAKIRESFNHLDIDSNSSSTNRTFGLVPHQYTHLRDSLIFNHERLLQHQDETVDLENLTSAAITNTNFQETPFSVSQSVSVTDRRFLNMANANELDGMRKHVGWVDNSQDAELMEALERASWQQNQVGNDQDTNQLQLTDGTANFNHHHLPSPPTSPLIPPSAPPEESRSLEPIYRNSAVNNPTNTTTVTTVYAYKSNRTGGGVKKMEIGEAEEDMPPPLHNMVRRVSLEDIQNQPGRERLSYEEQIQQTPYPFPPVTPTPYPQHGNLERVDTSQQMNTEILSGCQEIESKPNDTNLTPIMTNLGGQDDELDDDLSTFSVSKPVFPNPAELKWPDHMSLIESLPKMYHGWLATHFKKDPRVWLWKNKMGRRARQLLATSGDHASQVTMPPPLLETPIGARKPVIATSVTIPNELKDVRVGVHHVAKENQLEDTAPALEPADNEFQFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIY5</accession>
    <name>A0A1D2MIY5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001107">
        <property type="protein sequence ID" value="ODM92966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIY5"/>
    <dbReference type="OMA" id="HMEWRIC"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904114" description="Chitin-binding type-4 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="2">
        <location>
            <begin position="22"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="23438" checksum="C2278A19B188E99C" modified="2016-11-30" version="1">MSKFTIILITAFAAVFSGVNSHGRFMKPPNRSSIWRVPQFQSQNPPQNYNDMELFCGGVHQADNPGTNCGVCGDPQSQGAPRDNEVNGKWYRGIITGRYSAGQVIDIEVELTQQHKGYMEWRLCTNPRTENQACFNRYVLQLANGSGTRLPVTSTGMYRTQLRLPAGVRCNQCIIQWNYRSGNNWGDCGNGSGALGCGPQETFRGCSDISIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ81</accession>
    <name>A0A1D2MJ81_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001108">
        <property type="protein sequence ID" value="ODM92962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ81"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="8238" checksum="574708E6E9B249D6" modified="2016-11-30" version="1">MDPINSPLLPSSKADEGLLSPGLTSTTASSAGIRVQRYGRQVSGLVSAMGMKIYHSFRDREEFSILLLLQLTWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJM8</accession>
    <name>A0A1D2MJM8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_13554</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01001069">
        <property type="protein sequence ID" value="ODM93132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJM8"/>
    <dbReference type="STRING" id="48709.A0A1D2MJM8"/>
    <dbReference type="OMA" id="WSYPPSA"/>
    <dbReference type="OrthoDB" id="3264224at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF20">
        <property type="entry name" value="[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="305"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM93132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="450" mass="50859" checksum="ADF7024C1E6444DD" modified="2016-11-30" version="1">MSLSCLSSTRQMFRNSGSTFTPSKLLGMVSNYSSRPHNHRLDLSNDSSTRERNQTVISYYNQSAIDSAAAKPSVRLTPATIMYTGRSTDSSHALKSAQYLQKELPVRIAHRIAGFRNLPFIVGCNPAVLSVHEMYIRAFHILNDFPPIQDMKDEAEFSLLIENLLDDFKYVVTQLAEGFKACKKHIKVSCQNDDMNEPRDFYSQDKRSFPHYFVTTQQEDLARQFLDRTLTSRLGIRMLATHHLALSDNKPNHVGIINLTMRIKDVVEKWADFVTRLAQDKYGKAPRIKLSGHINATFPYIQLPLDYIFPEILKNAVRATIETHSDQNENTMPPIQITIANNDIDFIVRISDRGGGISHHLMTKIMQYNFSTADDSTEVGMDNHLFSNMMELSNSTTSGPMHGYGFGLPTSRAYAEYLGGGLSIQSLQGIGTDVYLRLKHIDSKSESFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKG9</accession>
    <name>A0A1D2MKG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transducin-like enhancer protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13287</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat Groucho/TLE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001001">
        <property type="protein sequence ID" value="ODM93395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKG9"/>
    <dbReference type="STRING" id="48709.A0A1D2MKG9"/>
    <dbReference type="OMA" id="ISAPACY"/>
    <dbReference type="OrthoDB" id="2624652at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000001">
        <property type="entry name" value="transducin-like enhancer protein 3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009146">
        <property type="entry name" value="Groucho_enhance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10814:SF36">
        <property type="entry name" value="PROTEIN GROUCHO-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10814">
        <property type="entry name" value="TRANSDUCIN-LIKE ENHANCER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01850">
        <property type="entry name" value="GROUCHOFAMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="270"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="307"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="349"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="507" mass="54407" checksum="55ACF902043EE309" modified="2016-11-30" version="1">MRKFCLEREKGSSSQVSFYSAQKHLSDGEKSDQDLVVDDTNEDPLTPPNGNGTASPRENGIDKLPSKKDHLPPHSPRSGASSNSSTPSTNKKDEKPTTPTGKSTTPNSGSHSSSSGIKPVARATPLDPFFFPGPNPSFLHNNISPALAGYPRPPLVGYDPHSAMRGALGPAALAGIPGGKPAYSFHVSADGQMQPVPFPPDALVGPGIPRHARQINTLSHGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGTKSPVSQLDCLQRDNYIRSVKLLPDGRTLIVGGEASTLSIWDLASNTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISADGSKLWTGGLDNTVRSWDLREGRQLQQHDFSSQIFSLGYCPTGEWLAVGMENSNVEVLHCTKPDKYQLHLHDSCVLSLRFAACGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKP6</accession>
    <name>A0A1D2MKP6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Neuroglobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000973">
        <property type="protein sequence ID" value="ODM93481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKP6"/>
    <dbReference type="STRING" id="48709.A0A1D2MKP6"/>
    <dbReference type="OrthoDB" id="6344802at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="8021" checksum="E09AA450FCC0215A" modified="2016-11-30" version="1">MGCTGSKESDSGEPGTGKGSTTPATAANANAAATTGGASGSGVPNADPRIPMTAKQKYSIVASWKGIHRALEPTGILMFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML76</accession>
    <name>A0A1D2ML76_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_12895</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000914">
        <property type="protein sequence ID" value="ODM93786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML76"/>
    <dbReference type="STRING" id="48709.A0A1D2ML76"/>
    <dbReference type="OMA" id="HRAKQMS"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000004">
        <property type="entry name" value="Guanylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011645">
        <property type="entry name" value="HNOB_dom_associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF504">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07701">
        <property type="entry name" value="HNOBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 17" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="16">
        <location>
            <begin position="459"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="35"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM93786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="666" mass="76510" checksum="9A7FCD57F2B5B5E8" modified="2016-11-30" version="1">MFAPKINQSNNSKSQFFQFVEASLKNLDKLRLNTRRDSKRVKPARHEEDDEIHRDSITSESSKDKFNRSCRNKDHQRKLQTVQMIILPFIPIVALITQNLLGLQLVLQYQDEVQELDEQVAVAGDVAKLISHLQWERSEVAYFIFLNGSTIRANLTDRFFTTDGAINQMEYWPDIHPESSGARATFKSKLHFQVRLDEFRSRIGSNETKIYQVIEYYTQLNRVLLDFLTNEIKETNNSNVWRFLISYKNLLRSAENFGISLVYGINYFGRGELTPPNYIEYIRHDVLGMDYLNSSLEMASTANQYYKGVIDTLANFTALDKMRIKILLNERQPSNVEESIYYFESMSDFIVELRNLQRMIRTTIKETVSGNLQEANREAMIAIFVVILVLLVSPIIILMVHKATSTIKMFAEHLMEKADELRKEKVKSDRLLFQMLPPTVAQQLKQKRQVQAQIYDQASVYFSDIVGFTTIAAQSTPLEVVTFLNAVYKLFDARIEQYDVYKVETIGDAYMVCSGLPKPNGRLHAFEIATMAIDLLRQASVFRIPHRPNEHLRIRIGLHTGPVCAGVVGTKMPRYCLFGDTVNTASRMESTSEPLKIHISSQMKAALDVIGGFHIEYRGMIDVKGKGMMETYWLLGTVGQLERCETLDSTQSFDCATEPAFMEELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-05-29" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM69</accession>
    <name>A0A1D2MM69_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000871">
        <property type="protein sequence ID" value="ODM94022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM69"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="69" mass="7840" checksum="B002A6DE652AB91C" modified="2016-11-30" version="1">MNNKNLGAKCWIQTQSFGVENSLSSKRKCNKYNHHQFFKCFQSGTKNERVLVGINFAVCNPTTGIKTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMA7</accession>
    <name>A0A1D2MMA7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">14-3-3 protein zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12674</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000873">
        <property type="protein sequence ID" value="ODM94005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMA7"/>
    <dbReference type="STRING" id="48709.A0A1D2MMA7"/>
    <dbReference type="OMA" id="YDEMVNE"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000001">
        <property type="entry name" value="14-3-3 gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="5"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00068216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="319" mass="36314" checksum="5A091E83655C3FCF" modified="2016-11-30" version="1">MAVDKEELVQRAKLAEQAERYDDMAAAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGSERKQQMAREYREKVETELREICYEVLNLLDKFLIPKASNAESKVFYLKMKGDYYRYLAEVATGENRNTVVEDSQKAYQEAFEISKNKMAPTHPIRLGLALNFSVFYYEILNSPEKACQLAKQVKIGIACWWPYTNLGAIAVVDDSQKAYQEAFDIAKSKMQPTHPIRLGLALNFSVFYYEILSSPDRACHLAKQAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQNDGEEATEGGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MME9</accession>
    <name>A0A1D2MME9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SEC14-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12689</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000874">
        <property type="protein sequence ID" value="ODM93994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MME9"/>
    <dbReference type="STRING" id="48709.A0A1D2MME9"/>
    <dbReference type="OMA" id="CPLIPTF"/>
    <dbReference type="OrthoDB" id="30289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.680">
        <property type="entry name" value="GOLD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF66">
        <property type="entry name" value="PROTEIN REAL-TIME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="4">
        <location>
            <begin position="3"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="355"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="3">
        <location>
            <begin position="555"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="747" mass="84905" checksum="2E1D8FE8ABC582D5" modified="2016-11-30" version="1">MVQKYQSPVRVYKYPFELIMAAYERRFPTCPMIPVFVGSDVIKETESEDGSTQVVERRCKLNVEAPYLLKKIAGVDFVYFIQVNSLNRKNRALKIEAYNESFATRVIIHEVCNYFVHPENPSWTCFDQAASLEIKSFYGFENVVEKLAIKQYSANIAKGKEIIEFFLEELKNEGITEVPQWVESNPTPKEEDEEVEAETEEQPPSRKTSLDNSIKAPESESEVVEESSEVAASSSFKSHTSLSRQHSGAGDKASSGSHSSMRRESFAEEENKFRLDADYIQRFLGELSPMEESQLIQLRNWLAHLQKGNLPSDTMILRFLRAREFNIEKAREMLSQSLNWRKKYQVDKILSEYDTVEVMKDFFPGGWHYHDKDGRPLFILRLGMMDVKGLIKSVGEEGLLKMTLQCCEEGLRLIEDATAQSGHPITTWTLLLDLEGLNMRHLWRPGIRALLRIIEIVEANYPETMGRVLIIRAPRVFPVLWTLVRTFIDERTCSKFFFYAGNDYQGPGGLPDYIPDKYLPDFLGGTCTVSFPEGGLVPKSYYMPEEQLEHLALSDESIYKSVSLTKGQVHEVVLLNEDLGSVITWDFDVLRHSICFSVFRTKNPVSTPNGTLQTTPGLTENDHKSVIDKQWKEGHDFFRVETSIVCHDGESVQGSHVTNHTGYYILQWKFHDVAPTSHHLMDSISSYKAKVMYYYEVLKSSDYRGSMSSLQSQRSGLSSVSSKANSVIESASSNSAASVAVSSCPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMH7</accession>
    <name>A0A1D2MMH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Poly(U)-binding-splicing factor half pint</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12455</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM half pint family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000839">
        <property type="protein sequence ID" value="ODM94227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMH7"/>
    <dbReference type="STRING" id="48709.A0A1D2MMH7"/>
    <dbReference type="OMA" id="VHTHKGY"/>
    <dbReference type="OrthoDB" id="20943at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000380">
        <property type="term" value="P:alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12370">
        <property type="entry name" value="RRM1_PUF60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12371">
        <property type="entry name" value="RRM2_PUF60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000382">
        <property type="entry name" value="G-patch domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000136">
        <property type="entry name" value="poly(U)-binding-splicing factor PUF60 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000152">
        <property type="entry name" value="poly(U)-binding-splicing factor PUF60 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006532">
        <property type="entry name" value="PUF60-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051974">
        <property type="entry name" value="PUF60_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034209">
        <property type="entry name" value="PUF60_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034211">
        <property type="entry name" value="PUF60_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01645">
        <property type="entry name" value="half-pint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47330:SF1">
        <property type="entry name" value="POLY(U)-BINDING-SPLICING FACTOR PUF60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47330">
        <property type="entry name" value="POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="214"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="528"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="625" mass="67005" checksum="B3A32A3CC2C86661" modified="2016-11-30" version="1">MSIAGAATAGVYVDPLLKRQKIEDLGPTEFLSIPITDLNQSGPLVAGPGAKRDVAASVLGVALPKLERREQEDLARAKKYAMEQSIKYVLMKQTLAHQQQQAKSLQRHQALVLMCRVYIGSISFELREDTIRQAFAPFGPIKTINMSWDPVAQKHKGFAFVEYDLPEAAQLALEQMNGVMIGGRNIKCGRDTRIKFSHMDQVIDELMDEAKVYHRIYVASIHQDLTEEDIKSVFEAFGKIKSCKLAPGPTPGKHRGYGFIEYEAPQSAAEAIASMNLFDLGGQYLRVGKAITPPNALQQANPAQSQMPTAAAIAAAAATAKIQAMEAVTNTAAALGLSKTEVSPAIHSVVAPPTVLPVVGAVGGSSSNSSHSPSTRTTSSLSSTAGGLSNAPVIPSVPPPGLAIPGVGVLPVTMASTVASRMVAPPALAQPGLTLATAAPSQQALLTSGTSVTSTLPSSLYGNAAAVAAGLHLLWLLELLGIQREELVKKLVEENENVSLSSQENLSIKGQSARHLVMQKLMRSESSPVIVLKNMVSPEDVDDSLQDEITEECNRYGTVERVIIYQEKQSEEEDAPVVVKIFVEFTNPNEAETAKASLNGRYFGGRRVICEIYDYALYRNHDLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMS3</accession>
    <name>A0A1D2MMS3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Fanconi anemia group J protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000848">
        <property type="protein sequence ID" value="ODM94171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMS3"/>
    <dbReference type="STRING" id="48709.A0A1D2MMS3"/>
    <dbReference type="OMA" id="FSNDNAR"/>
    <dbReference type="OrthoDB" id="19182at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF34">
        <property type="entry name" value="REGULATOR OF TELOMERE ELONGATION HELICASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="50"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM94171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="751" mass="84759" checksum="9DDF1EFF35D3BE1D" modified="2016-11-30" version="1">MAQQVPDVDELEMEYQHLDFMEEMIDLGEFIENRRDEGEELQAQQLLVIQGIPVSFPGQPNPNQWIMMENIILSLSEGKNVLIESPTGSGKTLAFLCATLAWVHHQHQNQQRVPGGGETKKPVIYYTVKTHAQVSTVLKELRKTSYASPHINPLSNLKVAILGSRRQLCTNQDVIRNEHEESRDDACKRLHANFEINRQQQGQQLPLPTCPLYKPEEDDYFKNNRRCANGAIRDIEDITNSALVNQSCAYFGSRRQLASSDIVICPYNYIISSHIRNSVGIHLTNNIVIFDEGHNLQSVSCEEGSVSITLRNLRQIIDNCNNATRNPQAGGLLANKIRILSAALLNVWEWMVDPQTLPQTNADVLDAFRDFLDRDTVRNMENAVDYVINAIENEPTLGSGTAQEIRKFVSVLKLLYTRNAEGDGDNDDMILQNYFLQLENEGAVSRRLNIICLNASTVFGQISRQARSVLVTSATLSPLDSFQKDLGIPFEAPISLDQGIPASRYWITKVGSGPNGLELNLKSTSREVLALQKEVGQLVLKVCQTVPNGVLVFFPSNPFLQKMKRGWEQDPVEELGGRTIMSSINDAKHVVSEADMTDAVNTRELLRQYREQSRIGRGAVIFGILRGKLSEGVDFQDQEARAVISLGIPFAPPNAPTVFARKSSTSQLEYWRWYNTNAIRALSQCLGRSVRHQEDWGAMIMVDQRLIERAEDFRGMMPQWIEAETEAPRNQYNNFNDMIRSLQRFVAENNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN26</accession>
    <name>A0A1D2MN26_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000836">
        <property type="protein sequence ID" value="ODM94244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN26"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="204" mass="22358" checksum="B09E6A33DDC64D37" modified="2016-11-30" version="1">MCLFKSVNLSVSYCLSVEEAKSEGNCLAAGLLVEGAAEKPEKKLSIPAPKGDRQALEVGISKPESSFMLRLSQIETMASNKPVSLESSKDSSPVKTKALLSDEEDVIRRDPVSPMASQRTLNDPRLSSDFPEDNQNMSPADALQTSEPRRNLKDMPKPVSKFLISLPLLLVATSCFVQAKYYVGVFYILLVACIFFIVEVPRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ15</accession>
    <name>A0A1D2MQ15_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Papain inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000727">
        <property type="protein sequence ID" value="ODM94971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ15"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ15"/>
    <dbReference type="OMA" id="RIPITWE"/>
    <dbReference type="OrthoDB" id="9983485at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904356" evidence="2">
        <location>
            <begin position="25"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="3">
        <location>
            <begin position="26"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19740" checksum="FC6D73E04AC3582A" modified="2016-11-30" version="1">MFRLLTAWAFLYWTSFEFLSNAETYSGNATWYDLGSTACGVNYTNSDLVVAVSTTFWNNSADPNPNHDHICTKYIQVRDPHNSSVNPLTVKVVDKCGGCDEGDLDLSPTAFEHFYPTDKGLFEILWEFIEVTNKTEEIVEELNVYELDYYTEEQWKEIELEFNKLDALEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSC5</accession>
    <name>A0A1D2MSC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SHC-transforming protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11058</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000643">
        <property type="protein sequence ID" value="ODM95625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSC5"/>
    <dbReference type="STRING" id="48709.A0A1D2MSC5"/>
    <dbReference type="OMA" id="IWFHGSV"/>
    <dbReference type="OrthoDB" id="9938362at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030971">
        <property type="term" value="F:receptor tyrosine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01209">
        <property type="entry name" value="PTB_Shc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09925">
        <property type="entry name" value="SH2_SHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000377">
        <property type="entry name" value="Shc transforming protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000005">
        <property type="entry name" value="SHC-transforming protein 1 isoform 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051235">
        <property type="entry name" value="CEP152/SHC-Transforming"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006019">
        <property type="entry name" value="PID_Shc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035676">
        <property type="entry name" value="SHC_SH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10337:SF11">
        <property type="entry name" value="DSHC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10337">
        <property type="entry name" value="SHC TRANSFORMING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00640">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00629">
        <property type="entry name" value="SHCPIDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01179">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0727">SH2 domain</keyword>
    <feature type="domain" description="PID" evidence="4">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="5">
        <location>
            <begin position="321"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="184"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="231"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="418" mass="45407" checksum="52C4F154C24F896B" modified="2016-11-30" version="1" fragment="single">YIGCLDVNTSMKSLDFDTRSLIAKECINQVCEAAGFRSQDRKRKIDRRVARILGIRPRLDHAGSDVHLTITSTCLKLTSLDTGSVIAVHDMPNISFASGGDATMLDFVAYVAKDSIVGRACFVLECGSGLAQDVITTVGQAFELRFKEYLQKRPPPPRIPADDPEYYNDLPGKVPPDVQAANALDTKDKIQNVTKAKNATSSRAKEPPPLNLHSNSDKELSVNLIDFEAPTPPAFGPSVEDKQLDSFLLPGSDHTNGASSLGASGGTPSSVMGTGLGLPNSPSQPPQKDPFDMQPFSTTLPQSIPADIVESQRRLLDGEIWFHGTVSRGEAEELLKHDGDFLVRESMACPGQFVLTGLQGDSPRHLLLVDPEGIVRTKDRTFDNVIHLIKYHSENCLPIISAESMVLLRNPVPRVISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTR8</accession>
    <name>A0A1D2MTR8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000566">
        <property type="protein sequence ID" value="ODM96194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTR8"/>
    <dbReference type="STRING" id="48709.A0A1D2MTR8"/>
    <dbReference type="OMA" id="ALTCETF"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17274" checksum="892235944B00DC0A" modified="2016-11-30" version="1">MYMFGILCGSPIFGAVSDKLGRKKSILISTIIFVLAGPLVALSPNFTFVMITRFLLAFGSPGIYGTSFVLAIEVLGPSWRGLAGNLFCLPFAVGYMVRFLLCCLYFSPALTCETFLCTTLPSWLSSVSVLLLLSPRLFFFFCLGESAPRWLLRIRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUL1</accession>
    <name>A0A1D2MUL1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000504">
        <property type="protein sequence ID" value="ODM96777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUL1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904567" evidence="3">
        <location>
            <begin position="23"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="107" mass="11257" checksum="4F780832C749800F" modified="2016-11-30" version="1">MNAKLLLVLVLGLLAQVFFASAGDSGEANRVKRGGGHGHGGYDHGPGAGGGARGQSTSVGGSAPKWGRVMEDTENNLVLIYNIIYLLFLYVYLHTCIQGSCTKCLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV44</accession>
    <name>A0A1D2MV44_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein transport protein Sec31A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10096</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000523">
        <property type="protein sequence ID" value="ODM96585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV44"/>
    <dbReference type="STRING" id="48709.A0A1D2MV44"/>
    <dbReference type="OMA" id="HMASTEW"/>
    <dbReference type="OrthoDB" id="542917at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040251">
        <property type="entry name" value="SEC31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923">
        <property type="entry name" value="SEC31-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923:SF11">
        <property type="entry name" value="SECRETORY 31, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="110"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="770"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="864"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="971"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="772"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="971"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1031"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1105"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1166"/>
            <end position="1176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1176" mass="125655" checksum="45A129528A344D47" modified="2016-11-30" version="1">MKIKEIDRTASIAWSPAKLDNIYLAAGTAAQQLDSSFSTNAALELYQLNVNEPVVNCQFVIQCFLGCHGVGGEKNEYPAGLIVGGCDGGVMQVFNAYKLFQNEDPIVLTKSKHAGPVRALDFNCFRPNLIASGASESEIFIWDLTNPKVPMSPGAKIQPADDVTDLEWNKQVEHILASTFPARCVVWDLRKNEPVIKVSDATSRIRYKCVRWHPEVATQMCLASEDDASPVIQLWDLRYATSPLRVIQGHQRGILGMSWCAQDPELLLSCGKDSRILCWNPNYAHAGYEMVLDIPTSSQWSFDVSFCPKNPIVVSSCTFDGRISMYGLSGGAQQPVTSSKLADSFPGMDMSMSHAPLPTQPTSSQQLRDPPKWMKRPSGVSFAFGGRLISFQNVRTPSTQAGQPDKVTGNVNISQIVTLPEFIDRSKKLEEALQTGSLEYYCSEKARVATDSQEARIWEFLQASFSQNPRQAYVALLGFNTSEMTTKLQEIVNTGDIDALTNDFDALGNANVNDNLGALSGYQNGIGGLDKPEKIPEFSVPTDDSTDGRINQALLCGNIDLAVYLCLDNERWADALLLASKGSSELMFKAQMKYFEKVKGKSTNMIRAVVRQDLNHLVSNCELESWKQVLATALTYADETEFQTVAETLGQRLLGTKNDNLVQGALLCFICSGSLNQLVDAWVGSSGKGSSPDELQDLVEQVMILKKAADMWGRDANLGGGSLAGKMIEYASILASQGCLDTALNYLKDSNDPSINTLKERLQLSLGYVRPTRQQIAPRSRQSSESSAAGLRYKRPSHPSAPVKRGSDVYQPTDFSNLTGPVHPPSATYNTSSVLNSGYGAPNQFSPAPPSNNPGLLSYAQSNAANSVPTGLPPRPPTTGTPGGVPTLYNPAEAAAEMVPPATHEPLQRKMSGNALPRPPVSNVASGWNDPPPIIAKSKSLQQPSNNQQLITHPIFGTTPEPVQAASYSYGSNAAAPQPGGAYPPPPPTAASQPYGAAAPPPPPNAATQSYGGGIQPSQSAASQPYGGNFAPPPTATNFPPPTAANQPYGAPVQPPPTAASQPYGSTTTPPPSASGQQQYGSAMHPPPSQYGSNIMTPSVGAPQQYGTGISSNQPFGSSVPPPPTAATQPYGSAFAPQASNQQFAPPPTAANQPYGAAMPPPPPTAAAQPYGTVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW01</accession>
    <name>A0A1D2MW01_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09535</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000469">
        <property type="protein sequence ID" value="ODM97132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW01"/>
    <dbReference type="STRING" id="48709.A0A1D2MW01"/>
    <dbReference type="OrthoDB" id="428658at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="226"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="306" mass="35740" checksum="A8B610C92C489063" modified="2016-11-30" version="1">MHPKALRRHKHLIHNQSGESNKCPKCEVCFASPKTLWDHYHNVCSIEETVASLEELESRRLLESVKFGNRKAPIGKEEEEKGCRDGPFACEHCGSEYTQKATRDAHVRRIHMNQRFICDICDKEEPTGGKLWRHKVTSHPEVETPALEGWVCEYCSKPVLRNYQQHVEKFHPKKLAEFKKKGSYIRMTKGDTGRSMTKCPECEKEIRADRLRRHLKNVHGHGLELRPCQYCKKEFKTNSDLNDHIRTMHEFESFERKVDGNEAYQNRLEMTKADIPFLVRSVIRIVLSKGHRCVICSRPTLRFTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX19</accession>
    <name>A0A1D2MX19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000428">
        <property type="protein sequence ID" value="ODM97590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX19"/>
    <dbReference type="OMA" id="KCAGEEV"/>
    <dbReference type="OrthoDB" id="8248853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23992">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006170">
        <property type="entry name" value="PBP/GOBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01395">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00708">
        <property type="entry name" value="PhBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904670" evidence="1">
        <location>
            <begin position="22"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="146" mass="16037" checksum="7FAA5FCD6213B994" modified="2016-11-30" version="1">MIASRAQILGILLLGISAVYSQEETSCAGEEVKLDDSQKAVLSECLDKVGIKSIWKIPADKLACFGVCLLEKKDLMTPEGKINHEKALKYIEAVMPEKVRKPLIDGVDKCIKEHGDKVKGNDDPTCVTFMDVGQCVHDIFLDVCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX51</accession>
    <name>A0A1D2MX51_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_09061</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000427">
        <property type="protein sequence ID" value="ODM97620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX51"/>
    <dbReference type="STRING" id="48709.A0A1D2MX51"/>
    <dbReference type="OMA" id="WSETICE"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10324">
        <property type="entry name" value="SLC6sbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="567"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="606"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM97620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="692" mass="78099" checksum="F9CA0FCCDDF64C48" modified="2016-11-30" version="1" fragment="single">LKNKRLAMADDDNRNDLNLKYYPKIVNIELGIINTGYSVDENDVYYYKDDKEAEVKRNEELEKSQNGSQNEKSNAADEKDTKQTWDNQLEFLLSCIAMSVGLGNVWRFPFTVLFNHFNPKFRIAFENGGGAFLVPYIVSLVIVGRPMYYLEMCIGQFSRLVFNKRGFQHRGPVKVWEVVPFFRGIGYTSMIAVLCTVSFYCSIMAVTVYYFFASFLTPLPWSETICENNSTIPNSTLVSLLSENGPDVCELHEQSNTSISELYYFHKVFPQLEDINNGIGVPHWKLALCLLLAWVIIYLCIVKGIQSAGKVAYFTAIFPYVVLICLLIRGLTLPGSLNGIYYFIRPQWDKILSPKVWFAAVSQCFFSLTVGFGTITFLSSHNKFRHNVYRDAIIISITDTLTSLLAGCTIFSILGYLADSMGVEVSEVTKGGPGLAFIAFPDALAKLTWFPQGFAVIFFLMLFVLGIGSAVSLTGQLITIIREQYPSWKEWRVGLVMCLIGFCTGMVFITPGGQFILTLVNHNGADFIIYITAMLEIIAVSWVYGVNNFCKDLKFMLGRETELYWKVCWAFIMPVFLLSLLVYYFVQYDWLTHEGVQFPTSAVVCGWILSGISLSCLPFCAIHAVSNSPGETWMEKLKASFKPSSSWGPKIPAERELWLKMKEEDDVDCLDKKQVDRMSIASTVTPKSDGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXF6</accession>
    <name>A0A1D2MXF6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative ATP synthase subunit f, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08960</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase F chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000417">
        <property type="protein sequence ID" value="ODM97723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXF6"/>
    <dbReference type="STRING" id="48709.A0A1D2MXF6"/>
    <dbReference type="OMA" id="HKYVQPK"/>
    <dbReference type="OrthoDB" id="8921675at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019344">
        <property type="entry name" value="F1F0-ATPsyn_F_prd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13080">
        <property type="entry name" value="ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13080:SF20">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10206">
        <property type="entry name" value="WRW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="12671" checksum="9DE95557CDA91545" modified="2016-11-30" version="1">MGWGEYPPEYNARVHGPYDPARYYGKPDTAFGEVKVGELGGWLGRRKKSPTAMAQAVSRAWWRWNHKFTFPRKAGIAGPMQLICGSMFVFYVMNYGKLRHHRLYKYHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXT6</accession>
    <name>A0A1D2MXT6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000404">
        <property type="protein sequence ID" value="ODM97847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXT6"/>
    <dbReference type="OrthoDB" id="8263398at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="22677" checksum="98142D483FE4213B" modified="2016-11-30" version="1">MYGSSEWVAVEQYEIHISSSILSCQLVSILLCLLIAIGNASALPSLEFKNGQFYTISSLATGKAMTVAGKQFKLEADIVTSPWIAQDNQLWLALAESTQSGKPVSNRRNRKINATIESLPEETVVLTLDNNIVNLTQSLFNDSSSQKWITEDAGDGHVLIKNWGNQQCIKNFEKASPLGTLACNANDVSEKWLLEPVYVLKADDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY29</accession>
    <name>A0A1D2MY29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation channel sperm-associated protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_08719</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000393">
        <property type="protein sequence ID" value="ODM97959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY29"/>
    <dbReference type="STRING" id="48709.A0A1D2MY29"/>
    <dbReference type="OMA" id="DRYTHSH"/>
    <dbReference type="OrthoDB" id="416585at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036128">
        <property type="term" value="C:CatSper complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009566">
        <property type="term" value="P:fertilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030317">
        <property type="term" value="P:flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048240">
        <property type="term" value="P:sperm capacitation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028747">
        <property type="entry name" value="CatSper2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46923">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46923:SF1">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="6">
        <location>
            <begin position="131"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM97959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="478" mass="55560" checksum="F19E53C311461B04" modified="2016-11-30" version="1">MMGSEEPNPSSVIKITRHNHRDEFYFLRSELFHQMLMEDFNFLDAARSFVGNHEPPAFNYSDVSTIDNFRKASLAYPNGLIEFDHFTHRSPSRIFNNLNMNPDIRSLKFQARSSIWPPLSIWAHWLLHTTVYAFLMVLIITVNSVTIAVDQELDNSEDSQRFRIFLEAGDFFFLCLFVAEIILKFLDDFGGFWSEGWNVFDFLITATSLAAPVLDLAFPNSEENDDLEPVLTAVKYLRIIRIFRSLNVVTRIHKIQLIWGAVVKTFQAMIYITALMSIFFYIFAIIGIQAFDRYTHSHLPQLRYRLAFSNLHNAFVTLFQIFTLDQWYDVIEDTAIVMGYPLACTYILIWILLGSFIFRNIFVGVMVNNFQNIRQSLIEQSSQGTGMGRRSANVNIFALDALENEGLLSDDVLVDWEAEIFHSLELIRALENEMSPVFWPRDTMFQYYMLLEAYASNLDERAHLMHLLDKAVLHFMDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYH0</accession>
    <name>A0A1D2MYH0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">28S ribosomal protein S36, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_08979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-ketoglutarate dehydrogenase component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000418">
        <property type="protein sequence ID" value="ODM97705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYH0"/>
    <dbReference type="OMA" id="YINVSCE"/>
    <dbReference type="OrthoDB" id="2116030at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020373">
        <property type="entry name" value="Kgd4/YMR-31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10937">
        <property type="entry name" value="Kgd4-YMR31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM97705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="12542" checksum="9DBBC5FB4AD04CEC" modified="2016-11-30" version="1">MSQSISAKVKNLFKSMMKPSPAAVFQAVKSLKPHSPMIKFRYGGGVAGHSRMSAPPSPAMSAGGPPRTSPASTPTSPSKPNATTSLPIIEDWQLPARYQRRPIDPVEIEYINRGGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZC3</accession>
    <name>A0A1D2MZC3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000362">
        <property type="protein sequence ID" value="ODM98338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZC3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="8962" checksum="0854A3643EA1287D" modified="2016-11-30" version="1">MVMLNHLPLPKGTLPGWLTVNHRLAQDAEIGKSPEHCQLSRRPVFMIPVNGWLAEMKNLPTGQQKKIKDNKLHFRLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0G6</accession>
    <name>A0A1D2N0G6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transmembrane protease serine 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_07911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000325">
        <property type="protein sequence ID" value="ODM98769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0G6"/>
    <dbReference type="OrthoDB" id="10061449at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="469"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="786"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1039" mass="117463" checksum="BECE824AD49D2955" modified="2016-11-30" version="1" fragment="single">METIYAFTTFPEGVELRLLTFLYFCYATFITPVRFQYDHKRQKYTSHTSIFRKVSREKIPLHTTNIRFAVTVPGPSGVIISGVSYGVYFVGIAFLVTFLSSRSHNQMLDLLNLIQGSTHDRLKGKIFVPKNICIIIEILAVSVFSIFAYTYYTTSVYFTDGIEIVSKRFWYSFVEMNKRKAANITLDELEWWKMCFGGFLVFSQLDQQLFFGVSLVLLIFLGKAINTICVHFNTCLRDSRRYYNVSSEEVNVIGHIYRIRKMFNFGSNSFGVIAYMVIITETLLACINLVWVFKSDNIGVVATISTFAFCSGCLYFLFSTAKASRQIVAAMPLLYATKSHYRAKRPNSSHLNNHILIYEISSREVGLGSSGFFVITYSFIGVNKEISKNLINFIPIKMKFQLTCLLIVALSICVLCKPYRGQRFSWRQVVPRRSRNMMSHPWQNPMGYMHRPRYQTFNHFRSLDFTGRIIGGSNANPGEIPYQLLLTQKLANRRLKTCGATLVNSFGRQFAVTAAHCVWDHSASKIGSVGSFRIIAGEHDIKKTSGDEQQRSAAKVVMHENYATRKTDDIAIVFYSSPFTINSKVKAIRLPRKTWAQPGELKVTGWGWKKDSPNPISPDILKVVTLPTLNNGDCRRRFGQTGKMITRKMICGLDEGSKVGACLGDSGGPAAAWNKTERLWYLAGVTSFVKVTKLTEVYWYLKLQLETTWLKMSTQEKTPPEATGSSCVDLPPERRFNRRQFALNRPSYMTSRRYTHPWQSPMAFLYRPRYQTFNHIKPSESLTGRIIGGSNAFPGDVPYQLRLTMWTSKQTLVDCGATLVHAFDLQFAITAAHCVWDDGISKTGNPSDVDLFAGELNLKKATGDEQKRTAVKIVVPEKYDFTSIHKTDDIALVFYVPAFKITSKVKPIELPGWMWDQPDELELSGWGRTIGKQNPTTSDILKIASLPTVNNAECIRRFGATGSKITWQMICGLDEGFKIGACFGDSGGPAASWNDSESRWYLAGITSFGKGECGTGRQPTVFTRVSTYITWIWDRSGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1W2</accession>
    <name>A0A1D2N1W2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000290">
        <property type="protein sequence ID" value="ODM99259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1W2"/>
    <dbReference type="OrthoDB" id="6419576at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038602">
        <property type="entry name" value="Mite_allergen_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020234">
        <property type="entry name" value="Mite_allergen_group-7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008">
        <property type="entry name" value="PROTEIN TAKEOUT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008:SF9">
        <property type="entry name" value="PROTEIN TAKEOUT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16984">
        <property type="entry name" value="Grp7_allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904896" evidence="2">
        <location>
            <begin position="23"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="456" mass="50067" checksum="3E77AD967F97594B" modified="2016-11-30" version="1">MFHNFVCTFAWLVAITLAKVEGQFVIPQPGYQLNGSEFVDRVLENVREQVITLGLDPLNLPSIHFRVNNESVALRNGTIRGLSNIHRVGPVVVNVTILDTKYRSAFAVYNVSADQDVQIQSQMKNISYPNGHVHMDCDNVTVYQVFKLDHITQVLSLDEFELSIGECNYNVTGLGERAQNNSATINEIFARTKGPVLAVFNITFKILVNVALQAGLAFKILILKQWEKVYTALSENNYLKMVSKKLSATACLVLVVLITYSNAFFTLPKIGKSGNLEINGNKIVDNVLETIQKTIKTLKLDPIKTLPFDLGDVSLRNGTINGLSNIQRDGDVKVEVGLTSTLLTTSLAIVDMSTDEDVKLGEKKGHVHTECEEVTAHAVFKMDTLTSIISLKKFELSIGDYEFKVTGLGKDAKATGKKINDIFNAAKGPILKIISTALQTAINVALASMTASLFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1W4</accession>
    <name>A0A1D2N1W4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000289">
        <property type="protein sequence ID" value="ODM99273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1W4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="8327" checksum="FC71EB1342D7FC64" modified="2016-11-30" version="1">MYESDYMSPRHYLDPYAILATLGFGVFLFNVIFNLLNNTPAGMASGRSLDVADIDIPLALSDIVSNGNPEQVSCLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Z4</accession>
    <name>A0A1D2N1Z4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peripheral-type benzodiazepine receptor-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000301">
        <property type="protein sequence ID" value="ODM99074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Z4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="23982" checksum="23D7EE7BC15688A6" modified="2016-11-30" version="1">MGDVSSTSSILVVRKAHSINLLHTVFALFYLWLPQNVADELQKSQNSVDASVRKWNEVLVAIKGIERNIYRETDELIPKLRRKVAPPVTSQPLADQEFVPALESELARFNGISQMIPEIELKRGLVQAKILKASEDIHKRVDELEVPFELNKLTMEERKKLVRQWKEAETFIVEMKTTFEGIKKEWEETLEKFEDELEGSTRSQCALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2C4</accession>
    <name>A0A1D2N2C4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000302">
        <property type="protein sequence ID" value="ODM99055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2C4"/>
    <dbReference type="OrthoDB" id="6347385at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="384" mass="43606" checksum="AF9CFB566A33F885" modified="2016-11-30" version="1" fragment="single">RLWQLLYKRASGSGRWVVGLGTSLSGCAPSFGPRVYERVATAATQKVFLHYYLNSRWGKEDLSNTLIFVLSKLIQTGEESLKLVENYLVKVVELQLLEALTPVLRVTTNGLILLAKLAYRQVSILIFAIATFSLLIYYNWVFQRLWNVVCLPETYKLHQDDYRELKDSCSEWMWVKDRRADKVDSSSTVNADGESCRRAFEHYSSLVSPISDKVLVERRIKKSVKSGSASASARYINSVSDLYATDEIDALLDEIRDLEPVNMTCDSRTSVHSWDSHALYHNNTVASAVSLCCLCYAGTAKYGLFMLPYVGRIRLMLFIILFSCLVTALLLFLDISLLYHAFPVHYHKWVSLVYFMNTLAPLCSSCITTFILYLSVEPIVSLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2Q6</accession>
    <name>A0A1D2N2Q6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger C4H2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000271">
        <property type="protein sequence ID" value="ODM99549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2Q6"/>
    <dbReference type="STRING" id="48709.A0A1D2N2Q6"/>
    <dbReference type="OMA" id="INMANRI"/>
    <dbReference type="OrthoDB" id="20865at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045666">
        <property type="term" value="P:positive regulation of neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044069">
        <property type="entry name" value="ZF_C4H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018482">
        <property type="entry name" value="Znf-C4H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31058">
        <property type="entry name" value="ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31058:SF2">
        <property type="entry name" value="ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10146">
        <property type="entry name" value="zf-C4H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51896">
        <property type="entry name" value="ZF_C4H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C4H2-type" evidence="2">
        <location>
            <begin position="215"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="29147" checksum="5DB9C766423D3CE2" modified="2016-11-30" version="1">MMDVEERTASVLAKLELVKEIKTKTMQMLKLKERLLDEIEATRKEDRCLSDYRSEMEMLIQEKMAHVEELRQIHADINAMESVIKQSEQARNRALDTAKRLHAEYGPIKAEVDRLRQSCLGLERLPELHEEEPGLITQELFDQLPPAWTHSQQPREEVMPGIAYPQPPSATQAAAAAFIMSQSPLALMQSATKPERPPPPHIPPHPTGPTPTFRQQPPPMKSCLSCHQQIHRNAPICPLCKAKSRSRNPKKPKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3A1</accession>
    <name>A0A1D2N3A1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000257">
        <property type="protein sequence ID" value="ODM99749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3A1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="18865" checksum="D5285252BFF373BD" modified="2016-11-30" version="1" fragment="single">IENYFQLAETTTARTEQPTYTTTTTHMSLYYMLMSSDEGGKTRRMDGCGMESLAFRILHYNSNTSCFFPAFPPNVTSVDRPTDSVSVLLLYQPDDIVLCANSTLLNLGFGSVLWHSVYTSFCQSVDKGALIILISDCGAWVTSFSVFLLLPQNLHVHPHLVFLMCGNQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Y5</accession>
    <name>A0A1D2N3Y5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activating molecule in BECN1-regulated autophagy protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000256">
        <property type="protein sequence ID" value="ODM99774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Y5"/>
    <dbReference type="STRING" id="48709.A0A1D2N3Y5"/>
    <dbReference type="OrthoDB" id="6363363at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052596">
        <property type="entry name" value="AMBRA1_autophagy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874:SF1">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="469" mass="51330" checksum="A15248C01124030F" modified="2016-11-30" version="1">MRLEEIQMRISVLSQWSRARAMATSGTQTPQSFVRGTWPSSERLQQNGSNTDRERAGNEQLQVANAPTPSSSSSINSAGGGSSSSADPRFSRRRPYSRIARLVRNDIEDISDDEVLVSVPTRMSRLSDPSSMEQERARTERSDIPNREAGRGGSIRHHFDHWVLRSNPSNPVVHRYRPSAVLELAGSARTRAPPVNRYSGDNAEHAPVELPSGGGGESTRPRLHFPRGGSSRAAAGPVGGGHSNDGNNNNVGNGNEDQHADGAARFYPGYIPEILITPRTRPPTYFTMDAATTAFLSSRIQKWDFSEFLIPDITKRDEFVVVRECSLHSDACLDVSADSEFLAVLQPSDNGSYSSVGIYSLRDESLGVVLNVYHFDQNTVSVSISPSCDYMIVAYAGRGPLYRFVHPSRNIGKILSLTRDDEGLKLVPVKDLYADGQVAFMSINCMHWVPVAGYGIIYGTNTGDLVLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N426</accession>
    <name>A0A1D2N426_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron transport multicopper oxidase FET3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000238">
        <property type="protein sequence ID" value="ODN00020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N426"/>
    <dbReference type="STRING" id="48709.A0A1D2N426"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF511">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905004" evidence="4">
        <location>
            <begin position="25"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="33"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="160"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="447"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="559" mass="63270" checksum="CDFF6F1CD1F30C3A" modified="2016-11-30" version="1">MACSNKYTLTVPSLLVLASLTVNAKIVRHTFEVSYITGQPDGVWTKSILGINGKFPGPTIEGAVGDVAEITVINKIHDGQNVTIHWHGIHQRGTPFEDGPSQITQCPLKQGSTQVYKFILTEPGTYWYHSHVNSQYSEGLWGSIIVRSPRETWQSLYDEEILVTLNDWYHTSAIENEHWFVHPESLGAPPFPFSVLMNGVGRYPCDKAKLQSRLCDVEEQKRPVFRLQANKRTRLRLVSTSGWVAFNFTVEGHRLQPIEVDGIDLAVNQQVPQAELDQAVFIGAGQRYSFILIPEKGKNKTGSEFLIRANLRREYLFTRPGNINAFPNALITEVTGVMRYSADDPASQNSVTTQITPQLISPSFESFDYLRKYEAAQPWSSLRFIHEMNLKTFDGIPAPSDFHRNVVLRITFQNDWRGIKHGSFNGNPFKLPHGKPLLGKFGRIGDGPYDPRRHKLNLNGHKRDTVLVKEKSYLVIRFLADNPGVWTLHCHIDWHNLTGMAMTFVEAPELAACIRVPMEAKKVCADHNVTISDNMGANMGRRAWPQRTCKKVLHNHNHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4F5</accession>
    <name>A0A1D2N4F5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000233">
        <property type="protein sequence ID" value="ODN00111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4F5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905014" evidence="3">
        <location>
            <begin position="24"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="22900" checksum="D7610C889F5E491D" modified="2016-11-30" version="1">MLLKKATILSSVLLIFGVWVTQAMETEPFFEESHKTFQLPTSSAKPQSLVETNKSNRSLNITFKDEIDQIDDAVYMERILLQMFIVICGTAGVFVLCFVCCVQCVLQAKSHRNSELPPNIRALIAFQRDEETERNSFIPMHHHPWSPGILQIQDSFDYHYDENQDKPPCYDDLSPETPCSPPPPPYSPSFELSDSNNSDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N538</accession>
    <name>A0A1D2N538_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">High mobility group B protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000228">
        <property type="protein sequence ID" value="ODN00175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N538"/>
    <dbReference type="OMA" id="FIALRWR"/>
    <dbReference type="OrthoDB" id="498543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="108"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="108"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="23019" checksum="E7579DD059559D06" modified="2016-11-30" version="1">MAGRVNLMENVQDMEAFNRLTPKLKWEQLKNVLKPTRPPHGYQRFAKDFIARIKGTNNSGLPSLFTAAARAWMQLSDEEKNVWNQQYENERDAYLRQAEEWKHIKRSMMKPPTPYALFTKDFWAAQKKNVNRSGPKPGFNGTSRRIAKAWKGLTAQGRQKYVTKAEQLHKLFAAERQAVLTGRHRQFNVNWMEQAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5S0</accession>
    <name>A0A1D2N5S0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras guanyl-releasing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000196">
        <property type="protein sequence ID" value="ODN00623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5S0"/>
    <dbReference type="STRING" id="48709.A0A1D2N5S0"/>
    <dbReference type="OMA" id="KIMRRIT"/>
    <dbReference type="OrthoDB" id="74314at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF252">
        <property type="entry name" value="RAS GUANYL-RELEASING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="72"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25544" checksum="9335821DAB7AFA48" modified="2016-11-30" version="1">MFPLHFDVDDQLNKIVRKFSAQLEGEGRLEWANWLDLSEIPSYDWLRNNSVSKEPEAPRPNRKVSLIFNHLEPHELAHHVTYLEHKIMRRITFHDFKTYAENGTLADNPVLERSVSIFNGLSQWIQFVVLNRPTPQQRADVIAKFVHVAKKLKEIQNFNSLMGVVGSLSHSALARLSKTMECIPAEEKKVLSELAALVSSSNNFRQYRRALSQSVGFRIPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N724</accession>
    <name>A0A1D2N724_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Platelet-derived growth factor receptor alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000175">
        <property type="protein sequence ID" value="ODN01032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N724"/>
    <dbReference type="OMA" id="EDHIWEG"/>
    <dbReference type="OrthoDB" id="8251660at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905143" evidence="1">
        <location>
            <begin position="27"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="550" mass="61896" checksum="AAA2FDB72ACE8854" modified="2016-11-30" version="1">MIRRKCGTLLSIYAILLVTFLEYGNCASRSVKDPAKFKKSLNSVTSGNYERTPENTPRLGVCERDFAGRDTKVIAETGGGLPLVEDATLPILKVEDHIWEGKSIQLTCNASYPVKFEYIGPGMPIVKTETYRKAPDFYDPKTYSYAVSVVFSHTTEQQSGNYTCRSIKEPALATYMYLFVPGSHVFIGDSVTPANETILVRAKDRDQWVTLPCATSLKDSQVQLFKILASGRLQEIPLSDSVAFDVASGFHLKWRGAGALNETWGNYLCRVSGERYEKIHLRLMPPERNDPLMKIRVTYPELRLRIVISVLKYNWKKLVETVRPIVRGDAEENSLTYERESVTGSSKLRITFDQENDMIECCATEPQLRPKMKITPCSSTNDCQMAKKYLEKSCDLLKNTNCDNFVDQISGGCVGYPLATGSVSEGGILQCMVDETESVFMQFSYGSGGLVSDFSTIPQTSRILNIAREDTRNKTVGRYYCDANQFFFSHGLKWAIKKRDGSIELLPEKKFPQRPIKEIDETQAVEVICYAPVWDSLTDWKSASMKTPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N755</accession>
    <name>A0A1D2N755_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Serine protease snake</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05619</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N755"/>
    <dbReference type="STRING" id="48709.A0A1D2N755"/>
    <dbReference type="OMA" id="IALWINC"/>
    <dbReference type="OrthoDB" id="6339452at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000146">
        <property type="entry name" value="Serine protease 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022700">
        <property type="entry name" value="CLIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00680">
        <property type="entry name" value="CLIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905157" evidence="11">
        <location>
            <begin position="27"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="12">
        <location>
            <begin position="137"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="395" mass="43535" checksum="598997C71C2985B2" modified="2016-11-30" version="1">MKTNRRLVTIALWINCILIQLNTATSQLFVGRSCSTGGFAIVRGDCRRLTDCPAALSNLRAGIFPTLCYHEDDQPIICCPTKRVSAIKCDEYTKQVVALFGTSDIQPFYVGGYVDPSRIPGGGIRSAHCNNTKQALITGGRDADIDEMSFTVAIGYEDSGREISWKCGGTLISDQYILTAAHCLDGKASKPPTRVLLGDKRLQKLDTFSGARRVEANVQDIFVHPDYKRPLKYHDIGLIKLDKKVKFSRSVQPACLPRPEYRPETTSEFFTSGWGRLDSGKRSEMLQVVNLNRYSLKDCSKVFVEDSDGASSELPEGIIKSQICAGDKDGDKDSCDGDSGGPLTAKREKSDCIQYLLGVTSFGSKFCGYGSPGVYTNVQSYLNWIESIVWSDYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7A4</accession>
    <name>A0A1D2N7A4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">phytanoyl-CoA dioxygenase</fullName>
            <ecNumber evidence="10">1.14.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phytanic acid oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Phytanoyl-CoA alpha-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05532</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.18" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000169">
        <property type="protein sequence ID" value="ODN01143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7A4"/>
    <dbReference type="STRING" id="48709.A0A1D2N7A4"/>
    <dbReference type="OMA" id="CCAWTAM"/>
    <dbReference type="OrthoDB" id="2328924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048244">
        <property type="term" value="F:phytanoyl-CoA dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001561">
        <property type="term" value="P:fatty acid alpha-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000012">
        <property type="entry name" value="Phytanoyl-CoA dioxygenase, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047128">
        <property type="entry name" value="PhyH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21308">
        <property type="entry name" value="PHYTANOYL-COA ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21308:SF1">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0847">Vitamin C</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="36918" checksum="DE53DD4B921939AB" modified="2016-11-30" version="1">MSTAAAAERLRVIKGHLENGKLDANKGEKRFRFTLKSHPLLTEADRIFYEENGYVVVRNLLPHQLLDKWSQRFRDICDEKVDKGRITLMKDLSLAKTGVTGERLYNKIQDFMWDEVLYEFIAYPELCDLIECFVGPNMNAMHTMLINKPPDAGSETSRHPLHQDLHYFPFRPADKIVCAWTAMERVTRDNGCLVVLPGTHRGMLLPHEYPSWENGVNKMYHGIVGFDGHNRMHLPMEKGDTVFFHPILIHGSGANRTKGFRKAISCHYAASECHWIDVKGTTQQSIADEVEELAKKRGVTLDIQDIWKYRSRLVRGNEINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7T7</accession>
    <name>A0A1D2N7T7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05359</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000160">
        <property type="protein sequence ID" value="ODN01324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7T7"/>
    <dbReference type="STRING" id="48709.A0A1D2N7T7"/>
    <dbReference type="OMA" id="MQITSAM"/>
    <dbReference type="OrthoDB" id="239812at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000007">
        <property type="entry name" value="ATP synthase gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.10:FF:000003">
        <property type="entry name" value="ATP synthase subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF22">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039089">
        <property type="entry name" value="ATP_synthase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9 11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="32498" checksum="4976208378280D60" modified="2016-11-30" version="1">MFANQGRAVLVASASPLLWNQQNRGMATLKAISLRLKSVKNIQKITQSMKMVSAAKYARAERELRLARPFGAGSTAFYEKAEVTAPEDAKNQLVIAMSSDRGLCGAIHTSVCRLIRNRLQNTPDNIMVVCVGDKSRSILQRLFGRNILFAAKEIGRKVPVYEDASKVATAILDSGFQYDSGSIVYNKFKSVVSYTTTEIPIFSLKAINAAPKMTVYDSLDADVIQSYMEYSLAAQIFYTMKENACSEQSSRMTAMDNASKNAAEMIDKLALTFNRTRQAVITRELIEIISGASAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8A4</accession>
    <name>A0A1D2N8A4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-ketodihydrosphingosine reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000150">
        <property type="protein sequence ID" value="ODN01471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8A4"/>
    <dbReference type="STRING" id="48709.A0A1D2N8A4"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047560">
        <property type="term" value="F:3-dehydrosphinganine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006666">
        <property type="term" value="P:3-keto-sphinganine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="134" mass="14463" checksum="BAD37AFDDF15191D" modified="2016-11-30" version="1">MGDCCGCFLSVSLSSIGLAILLVAVLDWIQRRNKRNESLENQHVVITGGSSGIGKQVGILASQRGANVTILARDSKKLEEACAEVRAAAKDDNQKINYFSVDVTNYDQAEQTRTSKDALKKIGPVDKSLICCAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA16</accession>
    <name>A0A1D2NA16_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04757</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000133">
        <property type="protein sequence ID" value="ODN01925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA16"/>
    <dbReference type="STRING" id="48709.A0A1D2NA16"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="527" mass="58524" checksum="2FFE13DCE4023E62" modified="2016-11-30" version="1">MYPLRLPFQSVMKGVIVLILTTSYRLLPSMISKYVTLDKMMVLNSPAKEYDFIVVGAGSAGALLANRLSKYYTVLLIEAGGTPFPLQSVPVFAPLMLDNKDLTWRYFTVPQKYSCLGLVNKTSYWPRGRGLGGTSLLNFLAWIRGHPRDYDNWAEITGDKRWSYESLLPYFKRTENYLGKGSDRYHGHSGEIPISTARDRDKTLVNVFLEAAKELDYPITDLNAPLMKVLIDNQNNAYGVQYEHKGHLHKVRALREVILSAGAIGSPMILLHSGIGPSEHLQQVGIKPRVNLAGVGKNLLDHVSALVGPFTITNESFSQQHFTFVPARDSRPSNVIQYLASGDGPLAQSGSMASGFILSNKSFYTANQWPDIQLLLLGIPQDDEGLLTLSKAFNIDAATSRGQIKLASNNPFDPPLIDPNYYDHPDDMNLVLKGCEKLRFKSDEYWECFARHLTITVFHPSGTCAMGKLTNPETVVDSSLRVKGVRGLRVVDASIMPQIVSSNINPACTVIGERGAYIILNEQFHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA27</accession>
    <name>A0A1D2NA27_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_04734</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the P4HA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000133">
        <property type="protein sequence ID" value="ODN01935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA27"/>
    <dbReference type="STRING" id="48709.A0A1D2NA27"/>
    <dbReference type="OMA" id="YFEVNLP"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013547">
        <property type="entry name" value="P4H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF244">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08336">
        <property type="entry name" value="P4Ha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0847">Vitamin C</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905277" description="procollagen-proline 4-dioxygenase" evidence="13">
        <location>
            <begin position="28"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="14">
        <location>
            <begin position="414"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN01935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="537" mass="61072" checksum="5E76A3E23B686B33" modified="2016-11-30" version="1">MQSARTFHWIIAIGLLVLTYISDNAQGGHPVPYALSPVYLQYLEDLETQVYQLLKNTDSKTLFGKDAEEKQPFLLRYLEDYESSVNKSSITNHHEKDFVSSNPILALQMINRFVKYIKSDALKSATSVLVGKDILPTETEVEDGMEALLRVQYIYDLDAHQIANGMLDGTTTSAKLSVRECFELGKFAQDSAYFTLALQWYDVTLQKLKANDDSSSRTAALGLKEHFILNAIRATIDEHNDDYEENIADGDMYSFSTRIYNTNYSDIAHLSLRKRLTKELTGKFLPDKDPLFYQAVEANMMALCHGQNLQPEKEKAKLKCWLDTKRHPYWTINPLKIELLHEQPPITQFYDIFNDQWSAYLQFLSYEDLERAPDIPEATPRTAAYAWFEDNDIPYTPISKMVEFITGLNVVGSDASEALQVAAYAFGGHVEPHFDSVPKGPEDPFENPRGDRVTTFLVYLNEVEKGGRTAFPLLGFYVKPVKNSAVLWYTNLKNGDVDERTIHAACPVIAGQKWIATKWTHIKENILKRPCGLTPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB52</accession>
    <name>A0A1D2NB52_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04467</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB52"/>
    <dbReference type="STRING" id="48709.A0A1D2NB52"/>
    <dbReference type="OMA" id="MENSYYK"/>
    <dbReference type="OrthoDB" id="8183827at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005918">
        <property type="term" value="C:septate junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035151">
        <property type="term" value="P:regulation of tube size, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019991">
        <property type="term" value="P:septate junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004031">
        <property type="entry name" value="PMP22/EMP/MP20/Claudin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284">
        <property type="entry name" value="EG:80H7.2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284:SF6">
        <property type="entry name" value="SINUOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13903">
        <property type="entry name" value="Claudin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19842" checksum="BB9C76009CDFDE53" modified="2016-11-30" version="1">MQSFRADYPVTHRPTNTMIGHPYMENSYYKKRTLSGTVAIFVFLLAVILILVAFSTPYWLESDKRIVGSKFEKLGLWTHCFRSLPDPYDPAMGRFFSGCRWIFDPFTTGYQEIRSFLVPPFFVAVQFFFTMCFVTLLIAIVLVPAYILCYGPGHDYYVLLLRIIGIVLMISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBF1</accession>
    <name>A0A1D2NBF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBF1"/>
    <dbReference type="OrthoDB" id="8279338at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="245" mass="28190" checksum="F43B36020A6A7A0F" modified="2016-11-30" version="1">MEEILNTHLCPDPVISWGSSKSSETFDTSKVIAIIERSVKLKYRTVSYLSRFIPCTFIEDTENGLLGDEINPNETQISIKSINLHTQPWDFMSAPECSKLIMFKSWADYGKGYPPVTCGRDNYDQYLGPYGHPIILYYHLKDQGIAFPLFHPNYGQKNSDQKGTQELKYMLIYYSIRKNGMRSCRLQQYVLDPLQKGCSSTEPNCGEYDCTELETLYQKQLGRIRSSCSTVEFLSIHIFCIMFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBW0</accession>
    <name>A0A1D2NBW0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sodium/potassium-transporting ATPase subunit beta-1-interacting protein</fullName>
            <shortName evidence="7">Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03945</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cell membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NKAIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000097">
        <property type="protein sequence ID" value="ODN02732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBW0"/>
    <dbReference type="OMA" id="DMSTEYN"/>
    <dbReference type="OrthoDB" id="10071381at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002028">
        <property type="term" value="P:regulation of sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008516">
        <property type="entry name" value="Na/K-Atpase_Interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13084:SF6">
        <property type="entry name" value="SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13084">
        <property type="entry name" value="T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05640">
        <property type="entry name" value="NKAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="169"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="479"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="527"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="497"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="581" mass="64624" checksum="67D948A3711C475E" modified="2016-11-30" version="1">MGMCTDRRAHILFLTITVFQIILTIARWVIDFLGPMWSMILTDFLNIVFAILGFSGGYAQIKNYLFSYIVWSLLWLAWNIFIICLYIPIPSLEMYKSTVLSLGTGGLSYWETYAPGCEPDWASESKYMPTNCMFDPRLMEFIQAGVQVCLSVTGVVSAFILLCKHDFEDNKSSKESSNSNNKNNATPNTVPAFLSSNRSTIGSRMSSRNRPQLGLPKGAANSGNNGDSSDQVNGNDDRLRPMTPRRVKRRSARSIQSQKFGSAHDRRNNHNHDHQGHHDNERPSTSKGVPSSNNSGRSSLRSNASSRRSHRSSKRKQNHQFISPVNRLMQQVDSETSHEEPGRYTYRDQGHVNPVYVGPQSPSQPPPPPRPPSARSSYSNYHPARLPSATTNNLHPNVFNLNQNIFTNGGFDMSTEYNVSQHSNTTSANLYEDDINFFPDPGAGSHPPGNLSTTTTMALNSPLSPASSAASSKAPNGFAFSFNPHANNNNKINNNNVPHQQPRTDNPAISNQPFAYPLAHSPVSQESFPMWGMSQPQSPVQNHQPSRVPLQSPPYQNPPSFQPRPYARQLQPHPTNSETVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCC4</accession>
    <name>A0A1D2NCC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCC4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905350" evidence="1">
        <location>
            <begin position="24"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="15234" checksum="873E42117BE65B74" modified="2016-11-30" version="1">MHPSEEILWAIHTFMVTVIITEALEVQQEVSMSARSHLSVQRTKSAPLPNFLAQGLSTSPPMSQFEHLNPLGSNPADFLGGLNFSDAAALGLNADMLSEGGLGGDHSGLNQGSGATMSALDITSRLESLCLSMTEAALGLSCTNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND49</accession>
    <name>A0A1D2ND49_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hexosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03495</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND49"/>
    <dbReference type="STRING" id="48709.A0A1D2ND49"/>
    <dbReference type="OrthoDB" id="115198at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF379">
        <property type="entry name" value="HEXOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="409" mass="47078" checksum="50D2AD4D879C4E59" modified="2016-11-30" version="1">MRVHIKFITYILLGAILTAFVFLVLLLCIISDWEPISVRVQRVFEQKSNAPYKPKLNKFSITEMMGSTSVIDVVKPDEKTVILEPTMPFLKGGKSKRPFAVIMVTSLARFFNQRQAIRSTWYKWAHDLNIRIFFMIGHTGQNPILQNLEEEQRIHDDLIIDNFEEGYYKLPAKILRMVKWFNTTYLPENSPRYLIKTDHDVFINLLNLVNILRETPYYSNLVSLSGQNNSKLLLPDSVNIPFDSSDVESYFVGGQKFAKPEVEVDPDSKWYMDSKEREMLGWSGPYLPTYLNGPCYIISGNVVGTIYEASFNVPIFPFEDVYLIGLVAYDRLSLAISDIGQQMWLDKSYYCLVKNRTILQRMVAFHPLDHPSSMVKVCRRLPTCKRQMSSSSTSNNRNCNLLASIAKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDA2</accession>
    <name>A0A1D2NDA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Microphthalmia-associated transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03435</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MiT/TFE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000081">
        <property type="protein sequence ID" value="ODN03238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDA2"/>
    <dbReference type="STRING" id="48709.A0A1D2NDA2"/>
    <dbReference type="OMA" id="HINDMIT"/>
    <dbReference type="OrthoDB" id="6242697at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031867">
        <property type="entry name" value="MiT/TFE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45776">
        <property type="entry name" value="MIP04163P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45776:SF2">
        <property type="entry name" value="MIP04163P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15951">
        <property type="entry name" value="MITF_TFEB_C_3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="268"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="341"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="369" mass="41030" checksum="BCA5FCC25A5FED04" modified="2016-11-30" version="1">MLRLRKEIGIERILFSFIQLVTDLHRAKMPTPTRNVRLRANTKLDMDRQKAQEEERRDKELQKQQRAPSQSSAVPVSLPSVNVVVPPRVLQVHSALENPTPFHVEQKRRLNIQQYIANSLPDSHASSLGGTVAPLRHPVKHNRIQHIVADGAVSSAPPNYSTTPLSPASVLEPGAAPSPGPSQRSSVATSVNDEYEESILMELQELLMNDEKSGDQFNKSDQVASLPQPGFNRVSGVPEASSSCPADSTKDVVVNSNGEPARVSKDRIKKDNHNKIERKRRFHINDMITEQGRLLPKQNERHHEIIGDVKQNKGSILKASEPITYPVDDICDIMDEDRSIVTGSSDPMFGQPVEADDGFHHPEGMDFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEL1</accession>
    <name>A0A1D2NEL1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fructose-2,6-bisphosphatase TIGAR</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">TP53-induced glycolysis and apoptosis regulator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <dbReference type="EC" id="3.1.3.46"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEL1"/>
    <dbReference type="STRING" id="48709.A0A1D2NEL1"/>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="25"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="29632" checksum="0D412374795C6314" modified="2016-11-30" version="1" fragment="single">MSAQSDYNITNSTGSKTFATIYLVRHGQTIGNSSRMFLHPAKEVLSPKGQIQANAAGLHLANVKFDRAYASTLVRARKTAKLILEHSNYPVDTIKFDERIKEVDYDIFRGQSYDEPQKIRGKNIIDSYPYKEFYVEGTEEIESVLLRLDSFWNQLFETLDDASKPETVLVVSHGMLIRILMKYLNLSPQKYKVENFTDLLYTTYLKNTAYHKFQIERRRPTEDNDSKPRVIRFWETHKAPHLENLFPKKAKTPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF11</accession>
    <name>A0A1D2NF11_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-terminal methionine N(alpha)-acetyltransferase NatE</fullName>
            <ecNumber evidence="5">2.3.1.258</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_03116</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N-terminal L-methionyl-L-alanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-alanyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50564"/>
            <dbReference type="Rhea" id="RHEA-COMP:12726"/>
            <dbReference type="Rhea" id="RHEA-COMP:12727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133398"/>
            <dbReference type="ChEBI" id="CHEBI:133399"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N-terminal L-methionyl-L-leucyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50520"/>
            <dbReference type="Rhea" id="RHEA-COMP:12711"/>
            <dbReference type="Rhea" id="RHEA-COMP:12712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133377"/>
            <dbReference type="ChEBI" id="CHEBI:133378"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-methionyl-L-lysyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50580"/>
            <dbReference type="Rhea" id="RHEA-COMP:12734"/>
            <dbReference type="Rhea" id="RHEA-COMP:12735"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133406"/>
            <dbReference type="ChEBI" id="CHEBI:133407"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-methionyl-L-phenylalanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-phenylalanyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50528"/>
            <dbReference type="Rhea" id="RHEA-COMP:12715"/>
            <dbReference type="Rhea" id="RHEA-COMP:12716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133382"/>
            <dbReference type="ChEBI" id="CHEBI:133383"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N-terminal L-methionyl-L-seryl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-seryl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50568"/>
            <dbReference type="Rhea" id="RHEA-COMP:12728"/>
            <dbReference type="Rhea" id="RHEA-COMP:12729"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133400"/>
            <dbReference type="ChEBI" id="CHEBI:133401"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N-terminal L-methionyl-L-threonyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-threonyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50576"/>
            <dbReference type="Rhea" id="RHEA-COMP:12732"/>
            <dbReference type="Rhea" id="RHEA-COMP:12733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133404"/>
            <dbReference type="ChEBI" id="CHEBI:133405"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-terminal L-methionyl-L-tyrosyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-tyrosyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50532"/>
            <dbReference type="Rhea" id="RHEA-COMP:12717"/>
            <dbReference type="Rhea" id="RHEA-COMP:12718"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133384"/>
            <dbReference type="ChEBI" id="CHEBI:133385"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-methionyl-L-valyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-valyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50572"/>
            <dbReference type="Rhea" id="RHEA-COMP:12730"/>
            <dbReference type="Rhea" id="RHEA-COMP:12731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133402"/>
            <dbReference type="ChEBI" id="CHEBI:133403"/>
            <dbReference type="EC" id="2.3.1.258"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.258" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000069">
        <property type="protein sequence ID" value="ODN03566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF11"/>
    <dbReference type="STRING" id="48709.A0A1D2NF11"/>
    <dbReference type="OMA" id="ICCRLET"/>
    <dbReference type="OrthoDB" id="249087at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120518">
        <property type="term" value="F:protein N-terminal-methionine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000078">
        <property type="entry name" value="N-alpha-acetyltransferase 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="14">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN03566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="166" mass="18810" checksum="4B919800B7BBEDF5" modified="2016-11-30" version="1">MRPRIELGEVTVHNIRQLKRLNTVVFPVSYNDKFYKDVLQAGELARLAYYNDVVVGGVCCRIDTTEGQRRLYIMTLGCLAPYRRCGIGTVMLKHVLNYVEKDGNFDALYLHVQINNDSAIAFYQKFGFNIVETKTSYYKRIEPADAHVLQKNLVKGGSKGNKAVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFS1</accession>
    <name>A0A1D2NFS1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein mS26</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">28S ribosomal protein S26, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02737</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFS1"/>
    <dbReference type="STRING" id="48709.A0A1D2NFS1"/>
    <dbReference type="OMA" id="CENMTST"/>
    <dbReference type="OrthoDB" id="5988811at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026140">
        <property type="entry name" value="Ribosomal_mS26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21035">
        <property type="entry name" value="28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21035:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14943">
        <property type="entry name" value="MRP-S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="114"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="228" mass="26645" checksum="5609DC2C73656502" modified="2016-11-30" version="1">MFPLVESSLGRIILSNKGFRLRSCVEYQSVRNHKKPIWVPIAKSKMYKNIVDIPPPKMEFEEMTALQESYTLYNRSLWKFQDGITRELEAQQQKEAIQVSEDVELERIFKMNDVENENVRKNREESLLKEWEEVEKEILQMRKQKEEEELQTLEKTEEFLESEMKRLEGAIKPEDVDELIEKALGAVWDYNFAIDKTGRISQGRHNSVAVADISIPAEPLVTPVEGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGQ3</accession>
    <name>A0A1D2NGQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Laminin subunit beta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_02269</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
            <location evidence="1">Basement membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000044">
        <property type="protein sequence ID" value="ODN04402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NGQ3"/>
    <dbReference type="OMA" id="DYQCDRE"/>
    <dbReference type="OrthoDB" id="5985440at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030054">
        <property type="term" value="C:cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043256">
        <property type="term" value="C:laminin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070831">
        <property type="term" value="P:basement membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034446">
        <property type="term" value="P:substrate adhesion-dependent cell spreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009888">
        <property type="term" value="P:tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000011">
        <property type="entry name" value="Cadherin EGF LAG seven-pass G-type receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000074">
        <property type="entry name" value="Laminin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000084">
        <property type="entry name" value="Laminin subunit alpha 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000101">
        <property type="entry name" value="Laminin subunit beta 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000130">
        <property type="entry name" value="Laminin subunit beta 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000138">
        <property type="entry name" value="Laminin subunit beta 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000145">
        <property type="entry name" value="Laminin subunit beta 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000010">
        <property type="entry name" value="Laminin subunit beta 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000135">
        <property type="entry name" value="Laminin subunit beta 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.300.10:FF:000001">
        <property type="entry name" value="Laminin subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.300.10">
        <property type="entry name" value="Tie2 ligand-binding domain superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050440">
        <property type="entry name" value="Laminin/Netrin_ECM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013015">
        <property type="entry name" value="Laminin_IV_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008211">
        <property type="entry name" value="Laminin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056863">
        <property type="entry name" value="LMN_ATRN_NET-like_EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574:SF375">
        <property type="entry name" value="LAMININ SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574">
        <property type="entry name" value="NETRIN/LAMININ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24973">
        <property type="entry name" value="EGF_LMN_ATRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21199">
        <property type="entry name" value="LAMININ_IV_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00055">
        <property type="entry name" value="Laminin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00136">
        <property type="entry name" value="LamNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51116">
        <property type="entry name" value="LAMININ_IVB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51117">
        <property type="entry name" value="LAMININ_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0084">Basement membrane</keyword>
    <keyword evidence="7" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 12" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Laminin N-terminal" evidence="17">
        <location>
            <begin position="24"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="264"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="390"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="450"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="501"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin IV type B" evidence="16">
        <location>
            <begin position="540"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="754"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="802"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="1025"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="1076"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="15">
        <location>
            <begin position="1124"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1642"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1441"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1642"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="484"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="754"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="756"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="802"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="804"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="823"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1048"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1076"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1078"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1097"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1124"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1126"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="1145"/>
            <end position="1154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN04402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1768" mass="196467" checksum="23B1C53797DF7BAF" modified="2016-11-30" version="1">MTLKVYNKCWLRVHGYTPPIHPCDQGSCYPATGNLLIGREDRLSSSSTCGLNGEERYCIVSHLEDKKKCFRCDSRPQFMRHPSLSHRIENVISRLYPGTQQRSWWQSENGVEDVTLQVDLEAEFHFTHLIITFKTFRPAAMLIERSFDEGKTWKVYRYFADNCTDQFPRIDKAPALNLTHVVCEERYSGVAPSTEGEVIFRVLPKNVQITDPYAQEVQNLLKVTNLRIKFKKLHTLGDDLLDKRMDIQEKYYYAIYEMVVRGSCSCYGHASRCLPMPGVETRPDMVHGRCECTHNTKGLNCHECDDFYWDLPWKPAIGKQTNACKRCNCNNHAQSCHFDNAVFEASGNVSGGVCDNCLHNTMGHKCELCKPFYFLSSDRKIDDVDACQSCDCDPRGALDEGICVSKTDVDNGLEAGKCHCKSNVRGRRCDQCEYGFWDLQEDNPEGCKECSCHTLGTVENQGCNVYTGECTCKRYVTGRDCNQCLLEYYGLSEDKDGCKPCDCDEGGSYDNMCDVVTGQCSCRPHVTGRNCSTPEQGYFAGLPDHILYEAEVANRSPDVQVQIREPYRDGRDSTWTGPGFVRVYDDSYLEFDINDIMRTMEYDLVVRYEPQQPGWQQVNVLVIPDSPPDPNGPCAANQFQTGPTTLILRSETREEMLYPPLCLEAGKHYKVRLDFQPGDKPQSSVLIDSIVIIPKTTALPFFNGTAMNEYKRQMYERYRCDSAFVSASRYPVPDECKKLLTSVGYTVFDGAFECGCNLQGSTSAMCDPLGGQCNCKPNVMGRTCGNCAPGTFGFESGGCRPCECNPIGSLDNFCDAQSGQCRCRPNTYGLHCDQCQPGYWNFPNCQQCTCNGHADICDSLVGHCIDCRDNTTGTTCDRQVLIQLQKLISRLLNLCVESYYGDPRLGIDIPCRPCPCPGTISEGHSFASRCALDKQTNDVICECQEGYAGPRCDTCGDNYFGNPEVPGGECRSCSCNNNIDISRPGNCDLKTGECLQCLFNTEGFSCEHCMSGFYGDAISQMCRSCVCNILGTDGAAGACDRITGQCPCLPNVIGTSCDECREDHWKIASGEGCEACDCDPIGSLSTQCNLYHGQCECKPGFGGRKCDQCQADYYGDPNVECYACQCNSWGSQTQQCDRVNGSCVCITGVGGHKCDTCARGFIGTAPSCRECGECFENWDLIIGELKTKTTRVVDAASQVKQQGASGAYTSDFEIMKYRVDEVNRLLESSSVSSSDLDDLNDMIEERRQWFDTTSTGLDNASDELANISERILRSNSSLAVLESKVGALQSSATSLKDQAINLQEANVEGALNLTREAKRRSDDSVRRADGVQKLLSDSERQRRRIGALLDQISPQINKTQDDVSNTLEKLEADIDSVNGMFPDLNELVCDRAGDPCDSHCGGAGCGKCGGISCEGAVTKADNALKLAQDAYTALKLKDADADDLLRAVTQTKSEVDEAKNLAMMAYDETQTAKNQSEAAKAVLEQIEEDIKDALDTQGATPEEIRQVADDVMAKTITLRPEQIDELNEGIKTSVAALTDIEQILRETEDDLNMAKQLKERADYAASEAENVLQEAVQVRGELDKTLAAQRNAEAANEKAKEDIGAADLDLKQIGSETTNAETTASDSLTEIEALKRRLEELQKKNLQNERRRDQAKNESESALRNATVVQETAARLKEEYQQVSRDLESKLTLFEGAKEKDKLQNRANTLANNINDKRKELQEMENEYDEHERRAVSIANEIETLATIMEEHLRAIRKIEEYHRTCNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGV1</accession>
    <name>A0A1D2NGV1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Symplekin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000047">
        <property type="protein sequence ID" value="ODN04325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGV1"/>
    <dbReference type="STRING" id="48709.A0A1D2NGV1"/>
    <dbReference type="OMA" id="NVRYGIM"/>
    <dbReference type="OrthoDB" id="331600at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021850">
        <property type="entry name" value="Symplekin/Pta1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032460">
        <property type="entry name" value="Symplekin/Pta1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022075">
        <property type="entry name" value="Symplekin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245:SF20">
        <property type="entry name" value="SYMPLEKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245">
        <property type="entry name" value="SYMPLEKIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11935">
        <property type="entry name" value="SYMPK_PTA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12295">
        <property type="entry name" value="Symplekin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Symplekin/Pta1 N-terminal" evidence="5">
        <location>
            <begin position="175"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Symplekin C-terminal" evidence="6">
        <location>
            <begin position="923"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="399"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1163"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1184"/>
            <end position="1195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1195" mass="134388" checksum="0553D0FB3B6FBE1D" modified="2016-11-30" version="1">MSFHHPRSAAAQFYLDSSGGDYMEEEEPVHSGGRRLSSSGPSSQGGRKHSIGSSGSTSFPGGSGSSPTKVARHESFEPNDYQDEVEVAELLTKATVTESEKVKLENLMRVKEIIINKQPALLDNFLNEMLDFQTDNNADVRCYILEFVEDACKTDPETIPKVLHNMMLMLQDKSVTVQKKAVQVIAKLYKFTLMWLCRSKSVTEEMEAAWSAVCDLKKYILNLIDSDLDGIRTHAVKFIESVILLQTASEPDSFKRANDFCLDDVPITVKVARPRKLEEDSRNLFDELLKFHGSRHATSVNLMTCMGSIVLISKMRPHLMGRVVTAMEKLNVILPPTLERSQVTSVRKYMKVQLIGLLRHPKAIDYYDNITTLLTDLGATHSELHKALPNWDQIRAEKRKRQRALQEKEESNQRKRARMQEPVAVLEDYDDDEDMEKPPEKDKKEDLTELEQSIFEQLLTPETVAELLIASMEKVPDAMPAHFMSAFTPVDFAGTDGQIKHVSRLLAAQITAYQLGPEAALGQRVDQPDDEIEPMQIPTLGGGGQTLQSEKEKKLSLIQPSTGASKKKIPKALKLSEVTKPLSQDERQRHMAAAIKRILQTNQTLNPSKTRLICAIAANSTFELRYFIMQHIQEDIKNRLELGISWLFTEYCLCQEFVAKAVPMKHESTADRYEWLFFNLMKGILDYNNESEKTGLAWKLYLEPPMVPDKGLELLKALSSQHAHAAKGLQIFMELVLKRPKKLHYLSALLHFCVHSIDDVRGHAVSAILQIYEKMESKRGIIEDQAINTYCNSLRLPKPPEILFSEDLGRGKEGSGEWSDDLVKACLSLYLKLLNIKNSLIHELAKVYVETTADVKRSILRYVETPIRNMGMDSPELMKLLDSFPKGAETIITKIIHILTDKTLPSADLVSRVRNLYAKRVSDVRFLIPVLNGLTKQEILTALPKLIKLNPVVVKEVFNRLLGIHVDAKTQHASPITPVELMVALHNIDMSKCDMKTVIKATSLCFNETEVYSPEVLAVVINQLLEQSPLPTLLMRTVIQTLALHSQLSGFILNTLGRLVWTQPKVWEGFVKCCQRTIPKSIPILLTLPAPQLQQALDEATDLRQPLVTHLMSLTPQQRSCLPPTILNIVLGSGDAFGLKQESYYGDYEDEVSAIGGNLAGPSIHTIKDEPRSPAGDDELVMSIKDEPHDYTDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHA9</accession>
    <name>A0A1D2NHA9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pleckstrin y domain-containing family H member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000038">
        <property type="protein sequence ID" value="ODN04658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHA9"/>
    <dbReference type="STRING" id="48709.A0A1D2NHA9"/>
    <dbReference type="OrthoDB" id="6285196at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22903:SF8">
        <property type="entry name" value="MAX-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22903">
        <property type="entry name" value="PLEKHH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="241"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="334" mass="34915" checksum="B603B0C42F758E80" modified="2016-11-30" version="1">MALNMASLSVVKFPSWESRIYEVAAGGLKLPSREKASSANEIASASGALHQSCNSLGINISIPVYTTVKGRASQIRSAPFSGDSSDSSDGEEMGSGSGSGPHPMSSGETDISSPGKSAPSSIANSLSPLHRSSSSPSKSLRREPSFESEVSDDYAIPPDAFASETNSLDIALSSGCRNLGTSGAPSGSASSGGSGGIVTVAGSASGIPLGTTVPAGPSSSSSNNPSIPIINSVESSPRKESLEKAGYLTKLGGKLKTWRKRYFVLRNGTLTYWKSQVAKSRSARGPTGAEKSQFWQPNNCQELVQIGERCGQRFESRLTPEKDRNIISRYKLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHI7</accession>
    <name>A0A1D2NHI7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-binding cassette sub-family A member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NHI7"/>
    <dbReference type="OrthoDB" id="7857434at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1232"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1272"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1311"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1345"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1463"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="574"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1535"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1873" mass="213225" checksum="F730AFCC9BCDC8B4" modified="2016-11-30" version="1">MTNSQQSLIETDVGGEESRATESKAQSRCPRDTSTKKKIRKCLRPDIGHSRNIFVTTFYRIWMYRRRHLFTTMVQLIVPPMIILGMIMYMGTLLTVQEKGWSRWDKISQKDLIGGVCGVHCANPKTKGVITLHLKHSTTVFAQKFEMQLKETLAKSNIELLSVNKKDGIIKEAIHHHLRHDEFRKYIAGIEVQNPDVDSPGSLFGVKDNFKLAFTVVMAQKIPEFGFNHASTFFDLDEHQPEAYYQLVGIELAVFSAFRDLINMENNATNQIKSISLQSFPYPPHKSYSPINEDGVDWTKNINATLTVIFVLSMIPTVFTVVEGPVTEKEDGFKLYLQLMGYPRGAYWFSWILNQFLVQCIVVALQVFLLFFPINENTGTLMKHGDWRLWLVVLLLYNLSCLTFFVFLAAFFRRGKMATYLVILIWCLFYHVLQSHIPATLPLLHVYVHSTYSLWHLICLVPSGAIYWAVFSLTAITSDSWDTIGFPVSNSDFTLINAIVMMIADFFIYFFLTLYVDNLNPGPFQFSQPWNYFFEGIKPRFIDPLKDFAAEDIPSKESVCTQCENCAPISDAAIEFDKISKRFYVYDAVYGLENVKFTVHTAKITVILGHKDSGRTTLMRLVCGEYAPTSGTASVFGYDVRRDAQKVQSYLSICMEKNLLCEYLTVTEHMQLIGKLKGLSIKDTRKKAKLILESLGLLPQANDSVWRLVNWQKRVLCVAMAILGSKRILLLDEPTKGLDLDVQRQIWALLKQLKKNGKTILLLSNNIEEAYQIADKIVIMSRGKVAGAGTPNRLEQIFESGYHIHMNVIPNSNKDEILSFIQKYVPSAKEVEGSLRQVSKAMQISDWDKASQALLMEFTETSPTAVDNEETVIEIPDEGQGGSLTNSLVNVQDHDQQKESTPTIVQLNKDLAEPFNLTKLEISYVLPFQERTNFSQLFIQLDNTNTALKLGIKSYSVEMHDMEHTFYRVDDYVDIVNATNVRESTDRESGDFSDIKPLKLPDDGRTFEPLPTHSIDMTFKSKLCSGCIGLWALIAKRFWFFIGNYRHAIVQILGPLLIVFVTIYTTNMSFDHKLAIFNVKYNTSKKSDNPVAPYRINSGSSTAAEMLKSFERAIATPPNNIKRLKNLETSGFDTYITEDNRWALHNEVILGADFTEVDDPTEKTVTAMFSPGHLHAAPLAVLFMCQTILDFEFPNQNYDIEMNTQALAHDRNEIFLSGKVYPKILLMQSLDITFTVSIAFSYFIFTSGFAVQPCAEQVSKNKRYQLNIIWNALYWTGFACIDVILNLFFTTILALIMYFAPSHEVFKNPQFMILFIITGCLGGFSSTLMSYCLTHFLMKPATSYYVTLSINQVLGLFIFLLYTIFNFDYIGPYVGDVVSLCLQCIQPFTLPWNFYNAILLAFKQGRCLLLNPTVKAEMCSLAADSYKDINIIRKDCCDYTPPEWTFDFIVKEIEITLALKSKLWIYIVIQLSHCVGLCFLLTFMERRTIRRKLLNILIHPEKPVKLKDSMDLESIANNEKFVDTVEASIDRDKYFIVRNLGTSTFRRNILHGVTFATEPGKCIAIVGPETSGLTTLFEIMAGFSAISDGDITYGGHSLFSLTGRNKLLCQLGFCPSSDVTIDKLSGLQLLKLFGRLRGIPEKALPTHIDYWVQSLKLERKIKKRCQSYSAVIRKKLNVAIAAIGNPLVVIFDDPVSQLDPESRTQVCTVLESLVHANRVVILMTHELASVEKFCSKLIFLVNGQMHCTRDPEAIRQEISHEFTLVVRLKGVESGNIDFRTYTDFKSRISGDIESATLQEEHSHTLIYRISSSKYRWSNIFDIVEKITSEFSSIIQDYKIRKRSLQDVFNSYASKQQVFRTGLSAWDEFRSAYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHP9</accession>
    <name>A0A1D2NHP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000039">
        <property type="protein sequence ID" value="ODN04615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHP9"/>
    <dbReference type="OrthoDB" id="8298862at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905575" evidence="1">
        <location>
            <begin position="25"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="648" mass="75741" checksum="B3EE803E59305A49" modified="2016-11-30" version="1">MGNFRFPTVEIVFYLLFMVKVCFTNTADIKVGPDQENKGWLRLCNKDSGSSQHYEVEADKCPHGAWLSESLQGGCVCLNGLWAISQSWCDEDYFVVYGKGHCFQLNNKIQKLAFLGNAKNPFESTNFLTKENGHVFRSFSDEFMMPYEYSTETNRTILRLRPGRQSRVVLEVKPSFNDWQEFRPVNEVWVDEEEPVCFETDEKNWTEDLLLIYKIKTGIKYIKVTEECPKPLFYDAIRDPSEHTTVFKLLPGQAIHMKSGTIIKASNNCPSDCASNDGSSLTELSKLIRHKRQADDDGPDFEPLELDQASKWEQKDYMNNVANLRVAKLELNWLLNKKRPPVLKTTEWRIMKRVKEVFVKACPNEEAPKFLANAMMRIFRLLYIESKDFYQNGHELEDKLQLNRILNHMDSCINEAKEYKFQYKWVKQQNAECRNGTRPGDPTVGNQEVRYCWCNYEMENVEFKYAYNTSTTDTDFNATRENNTITDDHAFYMSKKDRFNGSLYDFPIETVWKMISFSHYYCAKYFHLEPADHSAMMVALESLFSDEIIYRWTKPGSQATRVWQYLFSTFDLKKFAASMDTCVATAKYLSEYPYWISRPTLQSQGRKKRSLDREELWKGSAYCLDDPWDPVEKLGVNVPNKCADLNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIH7</accession>
    <name>A0A1D2NIH7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL45</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L45, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01647</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN05012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIH7"/>
    <dbReference type="STRING" id="48709.A0A1D2NIH7"/>
    <dbReference type="OMA" id="HTHMAAK"/>
    <dbReference type="OrthoDB" id="19619at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000003">
        <property type="entry name" value="39S ribosomal protein L45, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051975">
        <property type="entry name" value="mtLSU_mL45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tim44-like" evidence="9">
        <location>
            <begin position="148"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="315" mass="36683" checksum="BD29FC9BCE37378A" modified="2016-11-30" version="1">MIAFREVVRKNSLLLTKSNSYLFNSLGYVAPNAAFIGQDYKIQVRFGSTKHWNPKWKPFRRLKVIKVDLPDFNEAAESKNYSPDEVRAKMKERGMSPPRPWMERPFEISSTSDIFEPYVPPEGDGKASYISKEGAKQSAEMVSKKSKTWLAFRKIRNFDEDFEGKHFAAEAQKIYLNVHKAVSEKDKNTLRVLVTEKAYPEVTLNMRSRTIVWNFLDTIEEPRVVHARCTDVIQKENVFAQITCRFFTKQSLAIYDRFGRLAHGSEVVAKDVLEYVVFEKHLANQYGEWRVHGKIIPEWAPTNFETSYRTFRMSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIJ4</accession>
    <name>A0A1D2NIJ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000033">
        <property type="protein sequence ID" value="ODN04925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIJ4"/>
    <dbReference type="STRING" id="48709.A0A1D2NIJ4"/>
    <dbReference type="OMA" id="CHSYISE"/>
    <dbReference type="OrthoDB" id="1728874at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000230">
        <property type="entry name" value="Leucine-rich repeat-containing protein 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="246" mass="27366" checksum="A0C4A1B37132BC23" modified="2016-11-30" version="1">MGNQGYQQRLETATKTGVFHLSKAKLNEFPEELGGITKTLRNIDLSENRISAIPQNISTFVNLKNLNLNSNQIEAIPFEIGQLTKLETLSLANNRINDVPPTLAHLQKLRNVNLRFNLDSDSNALTSFPTVLCALKLLTVLDLSQNGITSVPDGVGDLQVVELILSQNRIRSINKDISKCPNLKTLRLQHNSLDIAELPTEILSDSQVSLLSVEGNLFDVVQLSNLDGYETYMERFTSTKKKILHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIM1</accession>
    <name>A0A1D2NIM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIM1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905610" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="49" mass="4949" checksum="CA872480C14E276C" modified="2016-11-30" version="1">MSKLFALFLLVALFAVASAQVVYTGGIGGVPVGLGYGVPVGVGGYIYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJB9</accession>
    <name>A0A1D2NJB9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-lysine(27) N-trimethyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.356</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_01338</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60292"/>
            <dbReference type="Rhea" id="RHEA-COMP:15535"/>
            <dbReference type="Rhea" id="RHEA-COMP:15548"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.356"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.356" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000024">
        <property type="protein sequence ID" value="ODN05360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJB9"/>
    <dbReference type="STRING" id="48709.A0A1D2NJB9"/>
    <dbReference type="OMA" id="HMVGASC"/>
    <dbReference type="OrthoDB" id="6141102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035098">
        <property type="term" value="C:ESC/E(Z) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140951">
        <property type="term" value="F:histone H3K27 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000001">
        <property type="entry name" value="Putative histone-lysine N-methyltransferase EZH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026489">
        <property type="entry name" value="CXC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045318">
        <property type="entry name" value="EZH1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048358">
        <property type="entry name" value="EZH1/2_MCSS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041343">
        <property type="entry name" value="PRC2_HTH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041355">
        <property type="entry name" value="Pre-SET_CXC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033467">
        <property type="entry name" value="Tesmin/TSO1-like_CXC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21358">
        <property type="entry name" value="Ezh2_MCSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18118">
        <property type="entry name" value="PRC2_HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18264">
        <property type="entry name" value="preSET_CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01114">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51633">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CXC" evidence="14">
        <location>
            <begin position="718"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="13">
        <location>
            <begin position="827"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="481"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="577"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN05360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="961" mass="108351" checksum="AD3388E3C919F1C2" modified="2016-11-30" version="1" fragment="single">VTTFTTEEEEVLLSDLIWRKESVTGSGVKGGTPSSSKREVGSNDKKSVENESSTTHSSSSSRDKDRGSETPKNSTRGLDHGLEIPPFLMATSVVRAAKAQAVGKIAPSLMAPVTSTTKSGGKCSLTPELKRRIRSEYFRILQQKRIRLKEDSKLAWIKNFNRTEGLMKEENRKWKEARLSNWEIDLDAPEHLGTMKRASLTLPMEHKSTHSVPIRIIHSIPSTPTMYMWSTIRQNVMVEDETVLHNIPYMGEEVLDKDGNFIEELLKNYDGKVHTDKDHDYMDDECFMEMVRAVMAMEESDIRNGLTKPHDKHSDTEEHFSDSEDDIHKGDSLLVKRMEPQQGMIINAEPGKVPRIKLPPNRIFKLLSEVFPNNGTPAELKEKYIELHEKHEPGAGLPPECTPNIDGPTAESVPREQTMHSFHSLFCRRCYKYDCLLHRLKAYHPEPKMLKRKCPEYRTKMPCSPFCFINLPEVQARIEAMASSTSDKDPDPVVNGEQGKVAPKKVRKQTSMESSGEQSSDDSNDSVAVLIGYRTSSCPKSDGNNGNRRSGGGPAKQPPLITDESKSDYVENKGSKLKSSNSGGSSSSNNNPGEKLDFKENPAMNFAMQSYLHFQQFPESSNKPGVDTAAQSLIKDFQPQDMDSWSGADQSLFRAIHKVFFHNYCLIAKSLATKTCQQVFYFAQKEAADMMTDGDSQKDVTPPPKKTKKKNRLWSLHCKKIHMRKDPTSNSSVSNFTPCDHPGQPCDSSCSCIQAHNFCEKFCLCNSDCQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCQMCGADQYDKSKINCKNVSCQRGLYKHLLLAPSDVAGWGIFLKDSAQKNEFISEYCGEVITQDEADRRGKVYDKYMCSFLFNLNNEFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAINPGEELFFDYRYGPTEQLKFVGIERESEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJG1</accession>
    <name>A0A1D2NJG1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like-conjugating enzyme ATG3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Autophagy-related protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_01291</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJG1"/>
    <dbReference type="STRING" id="48709.A0A1D2NJG1"/>
    <dbReference type="OMA" id="HCPTWSW"/>
    <dbReference type="OrthoDB" id="1584384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044804">
        <property type="term" value="P:nucleophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.50:FF:000001">
        <property type="entry name" value="Autophagy-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN05418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="320" mass="35913" checksum="C89D7DA063FA267C" modified="2016-11-30" version="1">MQSVINSVKGTALGVAEYLTPVLKESKFQETGVLTPEEFVAAGDHLVHHCPTWQWAAGDESKAKPYLPKEKQFLITKNVPCYKRCKQMEYDADQEKILDEGDEEGGWVDTHHFDTTVEQKICDMSLDSVTTKDDEKMKGVGGSSNTTAAEEDDEVALDMEEFEASGLLDEEDVQTRVEKPTDKDDSANAEGAAGGETGEIVQTRTYDLHITYDKYYQTPRLWLFGYDENRKPLSVDQMYEDVSQDHAKKTVTMESHPNLPGVVAASVHPCRHAEVMKKIIQTVTEGGKELGVHMYLIIFLKFVQAVIPTVEYDYTQNFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM99</accession>
    <name>A0A1D2NM99_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM99"/>
    <dbReference type="OrthoDB" id="8192147at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="307" mass="33613" checksum="236E15FB6C4D27CD" modified="2016-11-30" version="1">MDPSEPGERCLPGMGLSGWMKRTMERSYDLSDFCNSPPVDGFFYPNSQKGNIAGVAGKGSCSDSSKKEETRSCTVMGSVLSIQHSPNQHLSQTMGGDTSILNYGDQFHHHQMASAGCNAITGGSTSVPDYLKPVVGGFSSAPFSKQRALGLTQNMMDTANKSVEGNKTPQMTAEELRNWANADGNNEVYRPTEHSEIIKSHPTDDSAPTPVDHIVSHRLTPSMTRRAGNPFFTGGDREDDKSGPGSWLFRPGKKAGEMSSTQPENKLYEAKVEFQQQPNSKLAKKTVRYVPRPSELRELNFWSPTSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMG6</accession>
    <name>A0A1D2NMG6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-sulfur protein NUBPL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMG6"/>
    <dbReference type="STRING" id="48709.A0A1D2NMG6"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="21869" checksum="F78A5A86F336BD4D" modified="2016-11-30" version="1">MMKTKCYHFKTLESNGYVLDLCRHHQMNVSLILLQCSRSLAWFNGHVSYRKVGPGCSVAPSDVLFVDMPPGTGDTQLSFAQSVEVDGAIIVTTPQQVAIQDAIKGVEMFRKTNVPIIGCILNMSSYICNSCGEETKLKSNIHRLTDDNSIELLGDLPLDLNVSNACDEGHPIVLDSEKHVQGRKFETIVRKINDKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNK0</accession>
    <name>A0A1D2NNK0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NNK0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="119" mass="13475" checksum="83FF76861EC0E1B8" modified="2016-11-30" version="1">MSLILSTIMGGQRLAATSTTPAMELSLNSNVTQAFLDDLFIMTEQLQELERQHRAYTTTLERAAQELTRLYDALQSAQQEHMETMERNRELHAAFESTIQEATSLKATIEENRKEGPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0L7</accession>
    <name>A0A1D2M0L7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008598">
        <property type="protein sequence ID" value="ODM79383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0L7"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20905:SF1">
        <property type="entry name" value="AT07410P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20905">
        <property type="entry name" value="N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM79383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="20131" checksum="B32467F1035EDBBB" modified="2016-11-30" version="1" fragment="single">METAEVEGDWKNFSFHIAQRQHCQAITSHIRQHDWREDPLDKHFCNMQMRLPLFFSDSTVYAYTEQNLSLVAVDKSNGKVAGVQLNSTKYKSAVLLMAVINKPFPVHQTRKEVAKAQLLQRVNDEESIIRNNPEIDHFINFDKTVVAQEYRGQGLATEMWERSIKCRKQKSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M132</accession>
    <name>A0A1D2M132_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone H1-gamma, late</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_20019</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007769">
        <property type="protein sequence ID" value="ODM86664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M132"/>
    <dbReference type="STRING" id="48709.A0A1D2M132"/>
    <dbReference type="OrthoDB" id="10070184at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000140">
        <property type="entry name" value="Histone H1.0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="9">
        <location>
            <begin position="43"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM86664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="248" mass="25228" checksum="EA3A19CAEFCDAF60" modified="2016-11-30" version="1">MADTEAPETTPAAAPVAATPKKGKAAAKPKAAAKPKGEKKAPDHPSSNAMVIEAITKLSEKGGSSLQAIKKYIADVHKVDVVKQGTFIKKALKKAVESGKLTQPKGKGAAGSFKLAVKPKPEKKPAGEKKPKAKKPKAAGSPKKAAKKPAAKKAAATPKAASPKPKKAKAPKAAAKPKVTKSPKKAVAKKPAEAPKPAPAAPVPAAAKKAPAKPKSPKKAKAPKTMKAKSPAKPKTPAPKRAAPKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M168</accession>
    <name>A0A1D2M168_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly(ADP-ribose) glycohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007546">
        <property type="protein sequence ID" value="ODM86710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M168"/>
    <dbReference type="STRING" id="48709.A0A1D2M168"/>
    <dbReference type="OrthoDB" id="1937899at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004649">
        <property type="term" value="F:poly(ADP-ribose) glycohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990966">
        <property type="term" value="P:ATP generation from poly-ADP-D-ribose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046372">
        <property type="entry name" value="PARG_cat_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007724">
        <property type="entry name" value="Poly_GlycHdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12837">
        <property type="entry name" value="POLY ADP-RIBOSE GLYCOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12837:SF0">
        <property type="entry name" value="POLY(ADP-RIBOSE) GLYCOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05028">
        <property type="entry name" value="PARG_cat_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PARG catalytic Macro" evidence="2">
        <location>
            <begin position="336"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR607724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="586" mass="65451" checksum="6A6B66B7F5FF6BE5" modified="2016-11-30" version="1" fragment="single">NFGFQIMDNTNYGRQLVDPKIGGIPVQPQSYNPLGGGRPHFSNATPLHAGHVSPPSPGFCNPNLNFHMNTAGYAAQNFQTNAPGYPIQNVHTNTPGYPTQNFHTNTPDYSAKYHANVPGHSVQNLHVPPIHSNGDNQGQKNKISPRVVHISAALHNLLQSYPNEYSAVFFHQLNTNQQGGVSQHDVKWHHPVFVSTPFCSKNILLQGPGGVQKWNQIEKTLTSLSHNCVSNIQQQRAESLMRHAIAEYDHGVQAKTDFGTLKNSDVASSLVSTIPYIVGYALMLPSLLAEPIPFLKKNENKTIYFTKELQMKNRAGNQCNSQEIISFQRRCIKPSQNWFKSYAPLNLVKVEQNKKIEEAHSMLKVDFANKRVGGGVMNEGAVMEEILFAACPELIISRLFTESLEDNEVLVITGTEQFSEYVGYSRNFRFGGPASKQHVSLDQLGRIKNSFVALDALHFKAHEVEKQYQQNQIDRELHKAYVGFLTSNMEPISPIATGNWGCGAFNGDPELKFLIQWMAASQAQRPSIVYHTIGNVAQSHSIQSLTSFLQQKQMTVGKLYKLVVGYQKMRKRYPSIFDYIKAGKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M443</accession>
    <name>A0A1D2M443_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004875">
        <property type="protein sequence ID" value="ODM87671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M443"/>
    <dbReference type="OrthoDB" id="6778006at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="101" mass="11454" checksum="8E9986E59F5295F9" modified="2016-11-30" version="1">MRVVRCGGDTTVEFIGRVMKKLMTNEVGLKYSLWGFPKQHKLFEDSSLGSSQRFGSVFQNGSTHRESDEKSVSEWFRHSGDRIKQQNNKLLIKPSGSTSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M571</accession>
    <name>A0A1D2M571_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-Jun-amino-terminal kinase-interacting protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_18556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004074">
        <property type="protein sequence ID" value="ODM88126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M571"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM88126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="426" mass="45865" checksum="17A289E698578B1D" modified="2016-11-30" version="1">MSLLPTTRISNGVGDSSIPGQDEDILLVDFQPVVVTSCNQVMSSPSTATPTPMYPIPPPGSLLPGAHMSGGVRLKLPVSSAPPHTATATAVTQANLPYDENDEFAKHQALAQPTYMMNKRRSRRFVSRDNHMWDNSNHVGHHHQQPQPHMSSSLSSSEDSDTGFLMGTRKTAYTRRSVQRVVDPHPTTTTVGGNGSPSASTGLLPNLGNRKRVRRRRPSARNRKPVNNQRDKIPNPGDVLSFCCCLCDDDQPSHSSNRSSNASSFKNRYFRLACLVVIIIVIAVLASITVSLQRKVESLDGDLKRLDQAVGSPLSSDSSNGAKTPKPTESFETLLAAHNALNTTVTNLKAQLDQISGKLQDLQKQLNAAASKPDGVTEVRGDLAKLGSRVQELSSIVQEKLKDAAQNAIAKENESANAAKPTASST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5V2</accession>
    <name>A0A1D2M5V2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Leukotriene A-4 hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_18339</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003738">
        <property type="protein sequence ID" value="ODM88343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5V2"/>
    <dbReference type="STRING" id="48709.A0A1D2M5V2"/>
    <dbReference type="OMA" id="CTALQFI"/>
    <dbReference type="OrthoDB" id="79562at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000003">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000004">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="12">
        <location>
            <begin position="481"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="633" mass="73521" checksum="59548F4C272ED511" modified="2016-11-30" version="1" fragment="single">MLHIHFGNNYVVAAAEESVSKEDWLGKTDPSSYSNPEDFLATQLHIKWEVDFENKILSGVLSYEFDIINKEATYLILDTRDIEINKIASNGKGLLYKLGEKNKIFGTPLKIEIPNESRNEKALTIEIEYKTDPNCSALAWMEPHQTSGNKPFLFSQNQPIHGRSMYPCQDTPSVKTAFTAEIIVPKELVALTSAVPSQDAPKEAGDKRVYKFEQKIPIPSYLMCIAVGDLQSKKIGSHSTIYAEQEIIEKAVADFSDVEQLIEIAEKLFGKYEWEVYNLLFLPRAYPMSGMEHPCISFFSQELITGNKGGIDVLAHELAHSWFGNLVTNRDWNHFWMNEGFTRFADRKILGRTYGEEYRQLESIFGWSVLKYEAENLRNEPELAKLVVDKVVDPDRCLNGIPYEKGSAFLYYLEQTVGGASVFEPFLREYIKKYRHQSIESHQFKEELISHFAPEILRNVDWEIWLHSPGMPPVTNNYSRTLLDPITKLVKRWKEWVPEDRTEVPFKKEDLDGLRNIQLKQFVQELFNVGDLGLEKLKKIEEIYGMHERTRNIADIRARWFQLCGKVRWLETVPLMFEYVNAEGRFGALKRVYRELYEWEEIREAAIKNFNENKKYKMFVTVKVISKVLRLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7V6</accession>
    <name>A0A1D2M7V6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Gephyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_17643</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>molybdopterin + ATP + H(+) = adenylyl-molybdopterin + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:31331"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the MoeA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MoeA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the MoaB/Mog family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002957">
        <property type="protein sequence ID" value="ODM89039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7V6"/>
    <dbReference type="STRING" id="48709.A0A1D2M7V6"/>
    <dbReference type="OMA" id="CFKINTG"/>
    <dbReference type="OrthoDB" id="4349954at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099634">
        <property type="term" value="C:postsynaptic specialization membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061598">
        <property type="term" value="F:molybdopterin adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007529">
        <property type="term" value="P:establishment of synaptic specificity at neuromuscular junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097112">
        <property type="term" value="P:gamma-aminobutyric acid receptor clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072579">
        <property type="term" value="P:glycine receptor clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098970">
        <property type="term" value="P:postsynaptic neurotransmitter receptor diffusion trapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.190.11:FF:000001">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.980.10:FF:000001">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.980.10:FF:000002">
        <property type="entry name" value="Molybdopterin molybdenumtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="entry name" value="MoeA, C-terminal, domain IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.10">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.190.11">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192:SF5">
        <property type="entry name" value="GEPHYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="MOLYBDOPTERIN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="MoeA C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="MoeA N-terminal region -like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11 13" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="14">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="MoaB/Mog" evidence="14">
        <location>
            <begin position="371"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM89039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="607" mass="64974" checksum="42EFC5496B1BA849" modified="2016-11-30" version="1" fragment="single">SDRCARGETEDLSGKVLVEKVESDDFSGCVVKQDIVPDEVDVIKKTLELWSDSGDVDLILTTGGTGFALRDVTPEATKLVITKEAPGMVIAMIKGSLEVTPMAMLSRPVCGVRGRTLIVNFPGSPKGAKENFDFIKKPLKHAVDLLRNTTSQVEALHRSMQGSSLKSQVNAVNVADRARTSQFSTIPVSAAQDIVIQNCLEIPSVVEKKTLKNGLGFILAEDILAKDPLPPFPASIKDGYAVFVTENSILENTLLQVRGDSTAGESPDKCRVEEGFCIRVSTGAPVPPGANAVVQIEDTLLIEKTEDGNDEKVIRVTKPVKKAQDIRPIGSDIPANELIMPKGTRLGASELGILATVGRPVFAAYRKPTIGLLSTGNELQSPHDIVLDKGKIRDSNKTTLESLFATEGFQTLDIGIAKDTPDAVYQKLVEGLNKADVLVCTGGVSMGEKDYLKRVLVTDLGATIHFGAVLMKPGKPTTFATCTLNGNKKLIFGLPGNPVSATVTSHLFVIPALRKLSGWDIPMYPIVKVQLEKDVKLDPARPEYHRVTLNWNTETGIPLASSTGNQISSRLLSCNTANALMLLPKAGDLPNGVATVGSIMTALLLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8C0</accession>
    <name>A0A1D2M8C0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002785">
        <property type="protein sequence ID" value="ODM89233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8C0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="46630" checksum="42E4B8118B6DB640" modified="2016-11-30" version="1" fragment="single">QYLVAPTYLLSVIMGEPLQKLTMMGENIQPQSSSSDDVVEISLISSEDDKQESSSIQEINTPNAKNNSETFPKVDPCLLCAQPAVEYDGEGKPIMNQKGREQAPSTIIVASLASSARDSASNPFTGWCESLINNLAGVYTRLEAIKTELKDRMEDGEEIYMREELYSKQNVRYFNFRKLVLGAKFQGTVKGRMFQRNHPQSPSGLTRPTCFDESMFPPNHPGSQSLLKTTNADAEGNGSSSSSSSSSSPAVPPPPSPRKKWKGATSRIPPVASLSQGSSSTTNSLKPAGIGATFDPTRFHRFSKRKPPVPSPLKRNPPNLTPVYIPDTSGFMERCPDSGKITYYSSGATKKARQILSFTPPHKTTSTNAPSVGNSSLFSTCEKSSSSNSFVTTFSNSTLTAGDVKCAKEMEAKIRTLMGPWTRKNLSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8Q8</accession>
    <name>A0A1D2M8Q8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_17400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Recycling endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002753">
        <property type="protein sequence ID" value="ODM89284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8Q8"/>
    <dbReference type="STRING" id="48709.A0A1D2M8Q8"/>
    <dbReference type="OMA" id="FVKAMIY"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002090">
        <property type="entry name" value="NHE-6/7/9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01088">
        <property type="entry name" value="NAHEXCHNGR6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="10 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0915">Sodium</keyword>
    <keyword evidence="12 13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="15">
        <location>
            <begin position="79"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM89284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="722" mass="80767" checksum="A3983D571124DF2C" modified="2016-11-30" version="1">MGFQRPNESRIRIENYLKRKMFPGARSPMSLCLIVVVAISVGIVHAEPSSDVELDEKAKANHRLDSLNILVYTILLSLTVLTIWSFKHRRIRYLHETGLAVIYGLIVGAIIRYASSATPYFHINVVPQNGTVAFNQSVPPDALWFRLNKTYSYVFKGEVKQEESKLIEQKATFDPEIFFNILLPPIIFNAGYSLKRKYFFRNLGAIFTYAFIGTTVSALVIGGILYGFVQLVPTTAQFTFVDTLYFGALISATDPVTVLAVFNDLHVDVNMYALVFGESVLNDAVAIVLASAIQNFGEEKTTGSGSQVYAFWESLGVFAWTFTSSFVIGGLMGCCTALLTKFTHVRDFPLLETALFVLMSYSTFLIAEAADLTGIVAVLFCGICQAHYTYNNLSRDSRLRTKQLFELLNFLAENFIFCYIGVSMFTFPKHKFEAFFIIAAFLAIIVGRAANIYPLSFLLNLGRKHKISWGFQHVLFFSGLRGAIAFALAIRNTLSIERQTLLTTTSVIVIVTVIICGGSTNQLLNWFNIPVGVDDEAECMQLHMRSVSDPFDDCANSCRTAAAMLEINKIAETGGTTYIPKSNSVLEVDSNGHYGYSKANQELAPDTTGSNSRLLTEVELIPMWRVEYLRQQDRALMAGWCTSFDHRYMKPLLTHSRPTLLETLPGFLTPLARLLTTTEQLTQERVEPINTLSGEPTFSQHFDGQDNMRRSKLNFAYEPSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8T2</accession>
    <name>A0A1D2M8T2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002715">
        <property type="protein sequence ID" value="ODM89331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8T2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="161" mass="18540" checksum="46A357ED54C7CFA8" modified="2016-11-30" version="1">MTFQGLSNYDMFKSNYEKQLIGKLRRLSIGARKLRLFVLHPGHDWSSCCVSLWDVFGGYSNLASIRNCWFSLLDLGTCIHRISPWWTGVTIPLFSVTLYFLATQSFRTIDMIRMKGIGLAHRHLLESVSIEFPPSRSLYSVILKKLHPHQTFSSDANLWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M903</accession>
    <name>A0A1D2M903_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002685">
        <property type="protein sequence ID" value="ODM89384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M903"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="515" mass="60231" checksum="30663AA2D25C3EF3" modified="2016-11-30" version="1">MDWSVILWILCSSPPSPKLRWEVGTRPSATVQRHDCQEPALHSRLHDKIQDVRDLIQDCQAAWDEAKRTELTLPTNETINRCADKKEELLGYINSTKYEQDVKFALLDALNIIISTFIISFHYDFHNGQKIPELPDSQSEYQVRLAPFPKMFQEVKLRDIEIDYMLWLTDEKISNPDTKPSPLYFIYVRELVFDKKMVTPNYRDLWSRTNPLSLTNMKDAVGNLTKQTHQEFMEDSNWETKYNQWRVDYSTFSRKEFDNFKTNAENLFDKNFRADLLNPEDPPHLYEWRKNNNNKAIFDMLLAWDRLDEALEELRCFHFISYAHFRPETLKMAQRDLNTTTLFNGSSISLGQPCVNAIYPDNATGIWSYSLTPPTCTLENNEICAPRPLSQFEEPDDPLRGGMSVLKPKWVFRINPNDERCYGQRTWVIQQFACRCGFRTDCGADLETKISCPLQPKDWEDRRQCRGSVGYPCRTLPLAPGKHNESCVTEYCDMEENSCEDRPWFSSLWGHGVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M990</accession>
    <name>A0A1D2M990_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-phase kinase-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002588">
        <property type="protein sequence ID" value="ODM89501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M990"/>
    <dbReference type="STRING" id="48709.A0A1D2M990"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000124">
        <property type="entry name" value="Protein CBG09126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="4">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="3">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="3">
        <location>
            <begin position="270"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="36352" checksum="0FC1911B25489E48" modified="2016-11-30" version="1">MSKIQLQTHDGQDFDVDKEILRYSATIVGMDILDQDGGQAEAANGKRIVLQVDANVFRLVIEWATHHHESCHFGGLCRANAEGGAGKESPEDKVEEWDADFLKKLDSDTLFQLMQGANYLDVKELSQILYKTVANILKGKTPEEIRKFVNLPVIQPTPDDDEKAVLNGPHVKLQSSDGMNKAVTLRTAKSIPVVSELMGNAGKRGLRSNGQVIKLPNVNYNALTDVLDWLKQQDEKIDDDDNWKEDFLDAMDQVTLLELLLASKDLGLEDLLTLTCQKVAKMVNEHTPEEIRKMMGIKDDLSAEDKAIIQKQNDWVIPPPSPNPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9W8</accession>
    <name>A0A1D2M9W8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002415">
        <property type="protein sequence ID" value="ODM89731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9W8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="23235" checksum="6265A4B11785DFC2" modified="2016-11-30" version="1">MKAYLLENQSFETTFQSAKTTSFITALVHCVADLQPTVGVEFEESRNFVSAIRSSLQYDSQLEAWEETVSIGINTPIQNMMVVNDLRCLPPVTSQVQVNGPFLDDLLCKYNELIKMKILMKFSSFRVGSRIMELFPSFNVESNEMICSQNGTQQGFTFEEELLVTWPVVVSEGLHVSGTVTLEIIGCPNASSNEDLCKAFQLLCFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA35</accession>
    <name>A0A1D2MA35_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16891</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002358">
        <property type="protein sequence ID" value="ODM89792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA35"/>
    <dbReference type="STRING" id="48709.A0A1D2MA35"/>
    <dbReference type="OMA" id="CAGMVSK"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM89792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="43787" checksum="FF31ABF0F2FE5017" modified="2016-11-30" version="1" fragment="single">AYRGFLEPFLHRTNLHIYRFAHVNKIHLGKKTKRAYGLTYKRHGVEHFVRAKREIIISAGAIDSPKLLMVSGIGPKEHLQSLGIKCQIDLPVGKNLMDHIMIVFGPFIVDTPGKTIVPGRDITLHTAVEYFSKWKGIMASAVAANAVAYIHTKFSKERVSSLEESPDIQLLLLPVNHNLHDAYEEATSVKPGLMRKYMEGLEEKDSFMVNVMLGRQRSRGEIKLASTDPLASPMMDPKYFSHPDDIRRLVDGINFTVQMVENTKAFRRIGTRLTKRHFPGCEKYELKTDLYYECYARHMTLTDYHQCGTCAMGYGSEDPKAVVDSKLRVLHAKGLRVVDASIIPEIPNGNINAAVIMIADKASEFILDYWGQVDSEMLSRFTARYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAQ3</accession>
    <name>A0A1D2MAQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002191">
        <property type="protein sequence ID" value="ODM90063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAQ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MAQ3"/>
    <dbReference type="OrthoDB" id="426235at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37238" checksum="172055BC1FE92ED0" modified="2016-11-30" version="1">MSRAPSTILTVCQSEQECEVSLIVHATRVLITVPPSRLVYLLTFDMNKTGSLKIELGDLLCSMVCITSCTPQTYFTQIYACKQYLKVNNLQRPYYLVEEDVLQDFAGEYNKRFNEDCVIIGLPSTQFDYRLLSKGMNLLQNGAPMIALNLMKRSVSPDVRNVYLGPGPFVSMLTFCSDSEPVTMCKPYKEFYEALCKKIGWSDLDYSKVLVIGDDINEDIVGAKALGMKAILTRTGSYQVNDERTVCTGLTPDATVENFALAIRCVLAAQAVSQMTEDDFLQEEKSSRGCGSDLTASNDEVLTKKMQGYVNADYKSQRNKECSNVVKLPSYIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBS2</accession>
    <name>A0A1D2MBS2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002011">
        <property type="protein sequence ID" value="ODM90361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBS2"/>
    <dbReference type="OrthoDB" id="5279008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13673" checksum="4FA101FE9D0CD704" modified="2016-11-30" version="1">MALEILDLPIELRLKIWRYISNSDVLRLRFTCKQINTEITQLFGISSKVTLRDDVNLAELSEFFSKTVYRCARIPKKCVFGDSIQLHDIFQRPEMLQTLEILGRASSYSSSRIIREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC54</accession>
    <name>A0A1D2MC54_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Valacyclovir hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001894">
        <property type="protein sequence ID" value="ODM90586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC54"/>
    <dbReference type="STRING" id="48709.A0A1D2MC54"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331:SF2">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="51"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="343"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="585" mass="66188" checksum="A94E19A4726AC6F1" modified="2016-11-30" version="1">MLGYCKLGPFDLLKICGRVRFSSSYREQQLRVLDLDINYVETLGNPQDAHPILIIPGGLGSVEMDIKPIIPALNKQKYKWIGWDAPGHGKSRPPTRSYLPSGYGCSYELDNLGFEQYTIVGWSGGSITAMMMANLYPERISSLVTWGAFGFLGPDVVRAFKNLKKFGALASPEPRRSQMIEMYGEKLFQEMWIDALNELIAMNETDFYGEGGSYQETIKNIQCPALVIHGTKDAILPVSYAQHLNSLFGNSRLHLVNNGTHNLHLRETNEFVSCIQNFLDSVIPLKRDTSAMMLGYCKLRPFELPKFYQRVRFSSIYREQKRRVLDLDINYVETFGNSQDAHPVFILPGVFGSIEMDIKPVIPQLDNKNYKWIGWDPPGHGKSRPPTRSFLPPGYGCGYELDVKYAAELMKNLGFKKYSIVAWSCGSITAMMMANLYPERISSLVTWGAFGFLGADVARFFKNSKKYGVHATPEPRRTQIFEMYGEKLSQKMWNDGLNELIAMTESNCYREGGSYQETIKNVECPALVLHGTKDAAFSVSYAHHLNSLLRNSRLHLVENGTHNLHLRDTNEFVSCIEEFLDSVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC79</accession>
    <name>A0A1D2MC79_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Valacyclovir hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001894">
        <property type="protein sequence ID" value="ODM90585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC79"/>
    <dbReference type="STRING" id="48709.A0A1D2MC79"/>
    <dbReference type="OMA" id="VRDHTII"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331:SF2">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="46"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="33413" checksum="ED4AD6F9268126BE" modified="2016-11-30" version="1">MLGLPGLSKFNQNVRFSSTFREQKLRVLDLDINYVETLGNSEGAHPILILPGVLGSIEMDIKPVIPELNKEKYKWIGWDAPGHGKSRPPNRPYLPSGYGCGYEFDVKYAVELMKILGFQRYSIVAWSCGSITATMMANLHPERVSSLVTWAGFGYLGPDVGRAFKNFKKFGALATPEPRRSQIVEMYGEKLLQEMWIDGSNELISLTESDCYGEGGSYQETIKNIQCPALVIHGTKDAVLPVSYAHHLHSLFRNSRLHLVENGTHNLHLRETTEFVNCIQDFVDSVVPVQPTLNKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCC7</accession>
    <name>A0A1D2MCC7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kallikrein-11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001865">
        <property type="protein sequence ID" value="ODM90648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCC7"/>
    <dbReference type="STRING" id="48709.A0A1D2MCC7"/>
    <dbReference type="OMA" id="TEYFCED"/>
    <dbReference type="OrthoDB" id="5565075at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24271:SF50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24271">
        <property type="entry name" value="KALLIKREIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903785" evidence="3">
        <location>
            <begin position="20"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="24"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="300" mass="32661" checksum="70AF7FF33BA63AFB" modified="2016-11-30" version="1">MFTKLYFLLAFCMLSIASGNETLVIGGVEAVKHQYPWLVRLYISIASGVTRRCTGSLISLDLVLTSATCVNGTNSQIIVIAGDHSIFQNDGTEQSLLGQEIITHENFNRGGNLENDIALIRLPSNLTETRAVKPLFLPLNSYNTSQATWGTVAGWGETRFSEGEEGPSSSTLMKANVTLLTEYFCEDAFPTVNEELQFCAEGDGKGAYKGDFGGPLLCNGMTIFCGIFTREIDFPPTTRIVGLFLNVVPYLDWIEEKMNLQPPTSTTEVSTTPQGGESTTSSGNHHVSSVILIAYLILMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCN3</accession>
    <name>A0A1D2MCN3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001870">
        <property type="protein sequence ID" value="ODM90644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCN3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="134" mass="14457" checksum="CD1A247AD99BDE24" modified="2016-11-30" version="1">MTAQQPLLLNKVQVEPPSSPTETVEGSILKSAAVTSPPYPSSNQEHSGDKTIPNSQADHDFLRDATSKHPQSTSAALLISPSVEKENLNTPQGTNAQGSRKRKSNLKDCESTYSVRKPKLASQSDTEENQTQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD08</accession>
    <name>A0A1D2MD08_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Solute carrier family 25 member 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15852</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001775">
        <property type="protein sequence ID" value="ODM90829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD08"/>
    <dbReference type="STRING" id="48709.A0A1D2MD08"/>
    <dbReference type="OMA" id="YWWGYES"/>
    <dbReference type="OrthoDB" id="1747031at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="17"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="150"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM90829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="35600" checksum="90EB4AA33E4C03C6" modified="2016-11-30" version="1">MATVVKVEEDDNRRFRITPIQQMMSSCSGAILTAFLVTPLDVVKVRLQTQQKALLSNKCFVYCNGLVDQLCHGANCQLNVWVKRQGHFTSTIDVFHKIVRTEGVSSLWSGLPPTLIMAVPSAIVYFVTYEQLRVRMVDLYHQSKSGRVEDPLYIPLVAGGLARLWAVTVVNPLELIRTKMQSKRLSYKELSRACGDLHNARGWTGFWMGYFPSLARDVPFSAIYFGCYEGQKKLAGYGSQEKETPILFSFAAGAVAGSVAGALTLPLMLSKLTNKLKWGKQISNSKQAKVAPRERNNQKNISANRNPRAFYRARTQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD24</accession>
    <name>A0A1D2MD24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gamma-crystallin B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001749">
        <property type="protein sequence ID" value="ODM90907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD24"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="379" mass="42796" checksum="C9470B654457037C" modified="2016-11-30" version="1" fragment="single">MTWRHPNRYYVLQDGLRISFYCAKSLIFNASNRFAKHIFLTIIIASLTDLDRVVLSANCFGSPLEVRVLNSSKMTCDKTLCLFQFAILIFTVNRLGCEAAKVKFFERNDFQGYQHEETSSENCKNLPYDHQNLNGSIKTNGCIMVYPERDCYYSGFIIRGQQSILWTPQQNINGDNLFKYKVRSFKDCTPLQNSDNVGVDIYKKQNRKGEIVAVYRDMCKCHDLPSVLIGEFPSANLHGNCVKVYRKVDCKGKQWIKYGEHDTTDFRIENDDVEPESDSPTIPTGPQQATQLGKQTFTNDGNAELEEIFEVSKEVIEVSQTELSESLSLMASISTSISSETGSEVSIPAVGKVTQKITARSHRTSDADRVGEKEIECGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDQ8</accession>
    <name>A0A1D2MDQ8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Farnesyl pyrophosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pheromone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001679">
        <property type="protein sequence ID" value="ODM91083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDQ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MDQ8"/>
    <dbReference type="OMA" id="THPRYAN"/>
    <dbReference type="OrthoDB" id="10257492at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042811">
        <property type="term" value="P:pheromone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="257" mass="30330" checksum="1B6508209075CEEF" modified="2016-11-30" version="1">MVHQAFGNLTAVEVYNFKKHYSILVEALDSQFRIDNFPCAPWIKKLLNYNVPHGKQLRGLFVPMTVKCFDNQPKNELMEQAYVLGWCIEMFQAFCLVADDIMDRSETRRGQPCWYRVDDIGVLAVNDSFLIEHTLYRILAKHFGTHPRYANFLDLFLETSYKTVLGQCLDTETERNRQNPECYSMERYKKIVEFKTSYYTIYLPMAVAVILLKNNDKHDLLKKVEDVAKVLDSFPDTRNELFGLLWKWKLVNWQSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF15</accession>
    <name>A0A1D2MF15_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nipped-B protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15096</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SCC2/Nipped-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001495">
        <property type="protein sequence ID" value="ODM91586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MF15"/>
    <dbReference type="OMA" id="SANFKDR"/>
    <dbReference type="OrthoDB" id="418242at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090694">
        <property type="term" value="C:Scc2-Scc4 cohesin loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061775">
        <property type="term" value="F:cohesin loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140588">
        <property type="term" value="P:chromatin looping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23958">
        <property type="entry name" value="SCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026003">
        <property type="entry name" value="Cohesin_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024986">
        <property type="entry name" value="Nipped-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12765">
        <property type="entry name" value="Cohesin_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12830">
        <property type="entry name" value="Nipped-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sister chromatid cohesion C-terminal" evidence="8">
        <location>
            <begin position="1280"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="663"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1492"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1557"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="663"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="680"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1493"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1557"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1596"/>
            <end position="1605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1641" mass="183993" checksum="F0D24B95F6EB88D1" modified="2016-11-30" version="1">MADKINSQLTGEERDDGAPVLAVSVPIEPLQNCTEDGDEAMLPDLSRMDMDCSGGENRMVVSDPSVSAEVEVYSGSMAEETELPEEEMEAASKSVYIFSGPIIKLVRCDPMLQRNLSRPPPPTPSKRPDSGVGVGSPKAKIRRVEGDVSGTFPRFLKLVGKLLDAVKNHGLDQEDDEDSEFVSSNQLLFSKSQLMELCAETANLKAIGEMDKVPIDMIVKILSILEKNIQDGCEMRWKPDDVKECEVDDKDDGKLQGRESTMEGLLRCALSSHIVLNILTSPNMPKRVYLEGVIDGVVAFTKFHLQNTIFPAFDPVYKVKPDAKESLSSSSKKKKKAGVATLVKDKNILYFYNKMHEVVGLLAELLVIQVLTDSTVLQLSSLGVAPFFVENMPQLQLSALKLVTGIFTTYVQHRTLLLDDILASVARLPTSKRNLRTFKLSSGESIQMLTALVLQLIQCVTCLPDQLAEQDSKKLINPEKDLLINEKFDKAVSIAGHFISVFLNKCGSKSDNACDYRLLFENFLQDLLSTVNKPEWPASELSLVLLGNLLVKKLGNKELDVPIRVVSLEYLGIAAARLRKDTVAAQCKMETIDRIIRNIKKGEAEDGNYAEFESEDEKTEYIQKILLDYLAVEANSDPVLLHARHFYIASWWKGAGREIEKRHKSLSRNRAKMRKKSESSSEDEETDEDVNLKIGKLTENRKQFLLCNINPFLQPNSTRKTDVIETYVDHQSAELLTRYLASTKPFSARFDFFLTKILSFSMETVVAIRSKALRCLAMVVEADPIVLARSDMQMWVHNSFVDQSISVREAAVELVGKYVLSGPDLIDKYYDKLSLRILDSGVSVRKRVIKILRDVCTQCPHFPKIPEICIKMIRRVNDEDGVRKLVMQIFQNMWFTPVPGGDDKSDRLLQKVLNIADVVSSSEKVGLDFLEQLLASLFRPKDVGGGEKDDVRGRRKIRDLEPPAAVLTASKEIVDCLVEKVLCLEEEASKSSMPSSRFVACIGTLLLFAKVRPQLLTKHCITLAGYLSLRCQNTADLQAVGNIASILELVVPLLLNPSDSFLAQLEEDCTKLVFKNERRVIEACMACLSAVVTKLTGNYNLVRDCFRKLHGKFSNQAMLTSQIKIMRENFSDPLLSQYRPQLRRAVYTIGLFCRYFDFTSPELYGNDFPADTVHQIFMELLYLVEGPLKDLQYLGIQAVGNLCVRHCDFMLGPQLKAVYQRLLSSTSSTSAIENRLKIQTLANIQLYLVEEDQRLMRQDSAWTKIDDLKGISSDLTAGMASTIIQLYLKEILEAYLHANIGVRRSAIGVIQLVLQQGLVHPIPIVPYLICMSTDEDQSIAIVAEKQLQETGKRYPQLLQGQGLNGIRKSLEFRRILAGGFSSTSKMKVVRGYRKHAEGGVPAALNGFLYSLLRSTKPGRRGVALSLLKQFDNNHHDNLTDLLYFADALAHFPYQVVDEPLFIIHRVDIIISVNGSNILQAFKESLLPVLKSEDSDEMDVDDDDDDDEEDEDVESLVSRITEGNMTTFENCIAASQGCLLLLNLKQHLKDMYGLSDTRMREYSPSDSTKAFEKPVHRKSSKHGLQFKPKETLNYLNSQSSTSTSDSSTDRKKVLVEYYLHFKQLMLSLDPEEDDEEDGGESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF60</accession>
    <name>A0A1D2MF60_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase subunit 8B, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001498">
        <property type="protein sequence ID" value="ODM91583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF60"/>
    <dbReference type="OrthoDB" id="7668083at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003205">
        <property type="entry name" value="Cyt_c_oxidase_su8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02285">
        <property type="entry name" value="COX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8459" checksum="F40A47BB147F08BD" modified="2016-11-30" version="1">MIGAVVKRAVTSRSLIQVPKRTLYPHTSSNHVAGMPRNRIPFPEKVATGIFLATCILATPAWVVTHMDDYRGGAVGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFV6</accession>
    <name>A0A1D2MFV6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001425">
        <property type="protein sequence ID" value="ODM91772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFV6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="373" mass="40813" checksum="016C87F1CF1206FE" modified="2016-11-30" version="1">MLRFLSNYLFQNENEPNEDPTATINQNPNDVKEQPSQQNDLEGPTKPMDLEEGNNLNDDDDEDQDEDWVLIGDGEKKPEEDTIDGNVSKLTSAEDVALVAPNDDDEEGQEDEESVQEQGNGLLWENKLIEHPSMSVYIDLAQSLTNGATSCMSLSSIAPATSPGESVIVLEHDDGESEDDDEMDILETIEVVQMELPKESLPAPKKSPPTPAAPVQNGRRKKGHYPCSSSNTGNMPRRHNVRNSKAFQMISSSSTPPSSPDLNEEERNRVTNSKKKRGNPAPTTPAVNQPTTACGIAMGDSPGGVNGPTSALGHHSSNMLNKNIKLLDLFPAKGSHSRKMEAQKLGATARGHHLQEGRRRLRPPELYEALPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGF3</accession>
    <name>A0A1D2MGF3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tail fiber protein S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001332">
        <property type="protein sequence ID" value="ODM92086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGF3"/>
    <dbReference type="OrthoDB" id="8291840at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903982" evidence="2">
        <location>
            <begin position="24"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="21119" checksum="21486E9B06DCC6C2" modified="2016-11-30" version="1">MKLTTRTVVLFGLLNSCVVGLYATQNVTDPSMKQGDVEFSNLLVLLTQFLTEVRADIQGLKGSLTSLEAELSRLRIETAKNISSLTEKSDQLTTDVYSLRDTALPAINGRIGGLEQQVAGVSQTLNSLKAAAITDVKFGPVEYSAIWKGPAFNDQVGFVITQVDNFNRDEYPDTAGRRKLMKMVDGNWRDIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGL1</accession>
    <name>A0A1D2MGL1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative nuclease HARBI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_14555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HARBI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001324">
        <property type="protein sequence ID" value="ODM92119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGL1"/>
    <dbReference type="STRING" id="48709.A0A1D2MGL1"/>
    <dbReference type="OMA" id="YEMSECE"/>
    <dbReference type="OrthoDB" id="7788538at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045249">
        <property type="entry name" value="HARBI1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930:SF85">
        <property type="entry name" value="GH03217P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="8">
        <location>
            <begin position="187"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM92119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="441" mass="50184" checksum="6919EF593AB9A81E" modified="2016-11-30" version="1">MIRESTVSEVCQHAVLELLLCDSSSEATGIFDQAIEDVMILQTARYTIPRQPLPKSDKWFTEILPEVDENRFRQFMRVTRKDFAFILQQIENDKCFNGPNSNLQLTVQKQLAITLYKFGVDGSGSSVCNVAALFGVGDGGTVMKIMGRVIQAILMLQPKWITWPNTQERLKIRNFMSDKLPGCIGYIDGSHIPLDEAPIDDPESYFTRKQRYAIQIQAICDNEKRLRNIVVGFPGSVHDARVFSREWIAADSAYANSKYIVTPFKSNASLGTARQRKQFNRYFSGYRVNIECCFGKLKEVFQSLKGLRVRVDSSNGHKLACEWVRACCVLYNIIVPSLDYEMSECELADEEFDVGIDEDNLADEQQRNFVFNFVLSFLPTAIDLQLSFLPKPTVVQPSPSRTQTFPEEADFLLPEEFSPRSIFLAAERARLSVSRIEILLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIZ4</accession>
    <name>A0A1D2MIZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polycomb protein suz12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_13703</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001104">
        <property type="protein sequence ID" value="ODM92976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MIZ4"/>
    <dbReference type="OMA" id="NIDVAMA"/>
    <dbReference type="OrthoDB" id="166746at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21521">
        <property type="entry name" value="VEFS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019135">
        <property type="entry name" value="Polycomb_protein_VEFS-Box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF0">
        <property type="entry name" value="POLYCOMB PROTEIN SUZ12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09733">
        <property type="entry name" value="VEFS-Box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Polycomb protein VEFS-Box" evidence="8">
        <location>
            <begin position="68"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM92976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="196" mass="22913" checksum="2F0337516B0A6463" modified="2016-11-30" version="1">MPGVQNQSQKRRRRKVILTKPIEHAVHNGAQKRRKRKIELDKSVEPTSKKLKRGRPKGKAAVKSSPNPNRQYYHASTNLPIKPNEKVDSDSTDDEVYQELNNRSIDKLRGVTPLQKDFMKLWNAHRQKTREVYRGISHLKDACSNFVDEHKVELKDTKMYREFMFHLTTLHEKNLMTRGALTEVVNRAHKIHEGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJN8</accession>
    <name>A0A1D2MJN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolysin TIAR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001065">
        <property type="protein sequence ID" value="ODM93142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJN8"/>
    <dbReference type="STRING" id="48709.A0A1D2MJN8"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="39"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="124"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="229"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="490" mass="54007" checksum="70094449986F8E5E" modified="2016-11-30" version="1">MENQHQLGQPDASASRLIADGQELPEPEVANTRSVSPLRELKVCNLDECTDEQDLTHLFSGMGEVEKLELVNAASSNGCPEAYVTFKDPSVASEALRSLNGQLYNGKTLMLSWAEKGGMHRRWYRIFVGNISREVDNEKLVELFEPFGRILRAQVVCEQPAGTSRGFGFVTYDTFESAKTAIESMNKIVVGETALETNWAVLRRRDTEDDLKQHPKYYNVFNATFPGNSTIYVGNLPEDVPKDSTEKLLHAAFRKYGQIKKVSVSDCVKYAFVVLDSKASATCAIIGMNGKALCSAGQADAGNLKPVRVNWANNQYQDTGSRGRFTRANYGYDEAGNTVAMDIDGGYSNAGFWTANGRTRSLESDTEQISKTFPCFGMLLQPLVDTLLTGVPTKGISMVAQVEFQRFRMALIMAIIITITIVEMEMLIALPTMVNLRLKRHIQSPQVAMGTVTQLLQCLHLSKVDLEAVATTGSLSGLICKLMYGVSRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJQ3</accession>
    <name>A0A1D2MJQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative E3 ubiquitin-protein ligase HECTD4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13387</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001028">
        <property type="protein sequence ID" value="ODM93296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJQ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MJQ3"/>
    <dbReference type="OrthoDB" id="8184572at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042593">
        <property type="term" value="P:glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043366">
        <property type="entry name" value="HECTD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46435">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46435:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="4">
        <location>
            <begin position="615"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="906" mass="101431" checksum="03C1BE00DCB2B526" modified="2016-11-30" version="1">MMESMINAPTTASSPPPPPSPVSTNKRTTNSRQNRKRPFPSKESKFKDLNGKGGGGSSKPGPSGFSGERSNPKGSSSEDGLVVFAKASEIDWFNSQVMITRVLKDIVWHSPSDTACVEATKVLIASVLDKMKGSNVHNRLLVISGAPVNIDGMSVEGSLIRALRGCGGVHGNEMWISGNSAVVEIRSLAKVNEAYEILKQNKVWYPLEDYVLYPTVNVFRVTDSLKLASPSDPQGEQILVKFLKNKIADPEMPDKLNFNASETLSSIFMSCYSTSISFVVESTDEEEEGDSEIFLSEEQLALKIPGNLLELFLEAVKATEEENYLKEVLNRFGEKRKKKKTSEEEKESHDHDGIDKLELEQQRSLREQNQGKSHENPQVESVSGLTLQGFLEWCSELMKTQPNLLWKGIFATGYDIRFDRIWLFQEPSLIYSHFHSDKWAFEKDAALISYMDSFSQSLHIDPTRIQPAELYLTESDYLNPNFNCLQDTEIGYLRVRWAMLQKMNTLLSKKLLAHISVHAGNSTRRSLAKLLHDSRQLLLYYTKDTFLYKIIHTSAARGSETPTPEVMLDPVSSIGSQDDSVFKNQLSQVIQQMSTITSAFYCVPQAQGADPALPISVKFQGEEVLGLSGSFRHFLLNAAKELQSETVKLLCRCPSADAGKHKDSFIITPGKLSYGEEDFLHFLGQLIGISIRSDAPLALQLLKVTWRSLLLGEKEENDCSDDMIEADVLCATYLQKLESFSTKMAFDNFLSLNSWPKFQYPSMDNNSVVSLCSEGSNISVSFSNRDQFIKLIKQLREKELRSSNRVTKILTGLSTIVPLPALLSLFTSDHLSLRIVGSPEVNLSILKNPAHVMYQVGVSENDPHIMYFWAALESFTPEELKKFIKFSANLERVASNLPLPSLRTIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKG3</accession>
    <name>A0A1D2MKG3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Charged multivesicular body protein 2a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000968">
        <property type="protein sequence ID" value="ODM93497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKG3"/>
    <dbReference type="OrthoDB" id="10252926at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="58" mass="6492" checksum="1AD55CECF609104F" modified="2016-11-30" version="1" fragment="single">FDFEAIAVDLKMEWLFGRRLTPKESLSNNKRALDKAVQDLDGERSALSHGAPGEEDNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKQ3</accession>
    <name>A0A1D2MKQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000968">
        <property type="protein sequence ID" value="ODM93495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKQ3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="69" mass="7797" checksum="A6795D96B3542C21" modified="2016-11-30" version="1" fragment="single">LFLCTSEEIDMTGYMIASAQDNETPNKICMSSDFLNSLLWKHPHLLELLCRDPDSLYKCTQETLQATGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLB8</accession>
    <name>A0A1D2MLB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Endothelin-converting enzyme 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13039</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000939">
        <property type="protein sequence ID" value="ODM93644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLB8"/>
    <dbReference type="STRING" id="48709.A0A1D2MLB8"/>
    <dbReference type="OMA" id="KENDKWM"/>
    <dbReference type="OrthoDB" id="7867452at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF228">
        <property type="entry name" value="PROTEIN GONE EARLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="13"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="121"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="433"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="638" mass="72896" checksum="7B7714DD1C675193" modified="2016-11-30" version="1">MQILGSLNASAEPCQDIWEFGCGGWLQNNPIPDSRAYWDSKLEHHLQVKGKVRTLLNTLPRTVIDEPNSVVGKMKRFYDSCMATEYIEPEGSKPLLRIISVMGGWQVLRTFQKNEFDFPRISPAGLSLPDKKYYFDEENKVAEAFQDHLKDVAQSLGANSVNAQQFAKELINYERRIAEVTPSPESLRDPVESFQKVTVSELRGMSSTIFWNDLLKSMFPGENINDNTEILILSKQYLTDISGIISSTDSGIKNNYLMWHLTKKYLPYLSREYSEAYDIFLRQISGRRQSRPRWEFCMDETLHYFTHAADFLLKENCQDRSERVDKVNDMFESMRHSLVDRINEATTKFDESLRNRLLDKLRLMTAQVGTTFTNQTDLKNYYLGLDLHKNEWFTNVVNAIEFERTLERKTLISTERDAPIRHLLAQQPINVQFLPTSNLIVIPELILQQPVLQLGSSHLPLLLGSVGVEIGEAIAQAFGIEQGLYGPDGKLMSDKDAKVQIMRDLIDQRRTCLVSFFVNIRLDDADYIERTSLDSTMHLAGIQIALDALVNHDLGTIFLGLPALENLPPNALFFLSYVQSQCSVQTLHYHELEHYSFTTLSHDHRTKGILRQLVGFTEAMECPSSSDLYADFSCGTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLC5</accession>
    <name>A0A1D2MLC5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RIIa domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000929">
        <property type="protein sequence ID" value="ODM93712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLC5"/>
    <dbReference type="OMA" id="ENESQGP"/>
    <dbReference type="OrthoDB" id="10249338at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22971">
        <property type="entry name" value="DD_RIIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059162">
        <property type="entry name" value="RIIAD1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="42802" checksum="2A368F66A157258F" modified="2016-11-30" version="1">MAGHELMNDLFAQAVLLASGAIPDEVRTPPRFGGDLNTPEEDQTQRESQVATPPTPPFPPHQLLVGAVHPPSPGFADGSSFDDEVSFDSTCSRSMEELESFKKKMIDDERLSQIFKMRYNFSERFDNRAYIHPHGMTNFDYKAIPEPRKPGFEKFKNKVREENYAYLAQHPEIGAMVSLLVKKILQVRPSDPAHYLAEYFTSRVNTSSDFKDVLDHEMQRISRYRVNKMKAAGKINIKTSNNMNSDATDLPPIAESDANFAKKLNIGPLAQDFYFDGTATPRKKSAVKEDDGKGRRKKGKKKHYCGCKDWKLKKGRRQDPEATLADVTTEEEEDDEVELEETLVLNNNGLPTAEQIAEQIMKDFIDTGEEEEVPYADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLY5</accession>
    <name>A0A1D2MLY5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_12639</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000868">
        <property type="protein sequence ID" value="ODM94039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLY5"/>
    <dbReference type="STRING" id="48709.A0A1D2MLY5"/>
    <dbReference type="OMA" id="HEMTHEN"/>
    <dbReference type="OrthoDB" id="428658at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000193">
        <property type="entry name" value="Zinc finger protein 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050636">
        <property type="entry name" value="C2H2-ZF_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772:SF13">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="542"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="570"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="653"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="682"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="777"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="806"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="835"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="865"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="137"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="210"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="595"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="946"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="603"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="955"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="987"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM94039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1023" mass="116158" checksum="CA5E17CA0665733F" modified="2016-11-30" version="1">MADHGECGNCKCLFDEQSSKITSILSTWGSRKDYPVPGLISVYEALSVIFEIPPLTPNKNETESGSTSFGLSKKQIFKQRSRFTKFLEDDDDDDESFEGGYALCLSCSEMLTVTYNSLQDFLSVCKAESQIGRILKELEKKEGSPNGKDNPTRKKSLGKSATDPTAIKSKEKHVQDVIIKTEPRDVEDNYYYDEDQNDGFSQTSEVGLASVTNTTGNNSDLDDNGGGISRPCSPDSYNSENDVKFGKTATVGGNSKVQKVEPQEDQFAPQRRSSRVRKPTKRTGLCENDFSDDSEVEENRYTNRKSKSSVQKPTGRLKYQKRVDSDDEYVPRDNEVNSKQRRPLFAVPFKTVSERNNDSSTSKTSELKQLECPTCGKTFLHENTLICHRRLVHRENIVLKRPSLSLSEMSIQNNRERVYNPASVDGKTSTCPVCRLKLPRNEIKSHLSTHTRSLSKPWMCTICGAICSNQANYTHHMNKHKSSVPCKRCGRKVPKVEMVIHMRACLKQNGGPGSYSCKNCSQTFKSSVQLMEHRSRVHGHVWKCKLCGSKFSLRAKMIEHMQSHSKKKAHRCKICDKAYDRSDVLRLHMKRFHRNEAPPSVLKSKELETGDNGRDDHDPIPAEDDSQTDAPPTPAASTQGVLPEVEPIYENRFICKPCDISFRLFEELEEHLVESHAEKESSTCNICTRKFQDNYCLKLHMKVHSETKPLTCFICSKTYKEKNTFFYHIKDSHQINSQTIIAKYPDVFSIYAQDPSKPFSKKSQRYAPKKPIQKGEYPCDICGKIFPYLGGVKRHIKVVHDQIRDFMCSYCGKGFSKKSYFLIHERLHTTTDAPYKCHLCGKGFRLPGNLRMHLKSTIHNPNKDFVCEVCGKGFNRMDNMKLHVKAVHMKIQIRKPRNRTGNSPPRSKLRLYIADDAQPAQNPGSSKSLFQQPASNETNERLKFEHENNSNTMAETSHSSQYSSESNYQHNHHHQPNLSMPAFDPQPGTSGQNLENVYSNSQGEFSTIHPSGLGFMFRGSQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN53</accession>
    <name>A0A1D2MN53_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000801">
        <property type="protein sequence ID" value="ODM94476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN53"/>
    <dbReference type="STRING" id="48709.A0A1D2MN53"/>
    <dbReference type="OMA" id="DIGQCEN"/>
    <dbReference type="OrthoDB" id="8171348at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055355">
        <property type="entry name" value="ZP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560">
        <property type="entry name" value="CYPHER, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560:SF9">
        <property type="entry name" value="ZP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00100">
        <property type="entry name" value="Zona_pellucida"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="ZP" evidence="2">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="29197" checksum="F01A18C6AE4DC1B7" modified="2016-11-30" version="1">MHSAETAREVSNTYYGRSYNLNVNVADSSRGFRVKECVAFGNTNVNSIVLFDENGCPESRIVSRWRYEGSTASTTIYSMFRFENSKRLNVQCVVYICETPDCSDSNSFGQDNCPSIPAPLIGSRATYQFQRDSNDTSGTGNVLTSLTVNVLDVGENNNEDGAGKDLLVFEPEQCVGSICPRWLLWLVITLGVLFLLMLLVNLFLCSALTCTCTRTELIEKEPSIIVEDYDPYRSSWAGSQYGGSRYSLNPPTSNLSGGNGPKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNG0</accession>
    <name>A0A1D2MNG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acyl-CoA hydrolase, medium chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12297</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000813">
        <property type="protein sequence ID" value="ODM94391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MNG0"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904319" evidence="5">
        <location>
            <begin position="22"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="33"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="685"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1326" mass="146921" checksum="5E5B1DCB47771F39" modified="2016-11-30" version="1" fragment="single">MKCIFYIVTALLAVAIRFSNGQPEEVIIDAGELGKIQGSNAWAMAGLNQTGRKYYWFTGIPYADPESYTGDNRFKASKLWDGQLPDIDGDGIFKADERKMIIHCPQKPVVSIGGADVTKLDPFNLIKSYYSRDGISKRRNPSTNAWGKEECLIVTVSTPKLPEGENPEKLPVIFFIHGGGFDAFWGSVFGGQRLLNHDVVLVTMNYRLGVLGSLNLGIEEAPGNGNLYDCITALDWVQKYIHHFGGDPNKVTVSGQSAGGVLATTVFLSPLATGKFHGVIGDSGSAYSVWANQKNPIEETLKVVKLTPCARFLDFTGLPNREQALAIRECMRWLIPDDLINAREEYAVNEHLDARLGYDAFTPQVQLSSLETPALTATPVEIMKKGLQNNVPLMMGATRHDGSFVVLTTFYDYLVANGLDSKVDFIKNDLLPKFLKGVGLEDPSGALTHSFLQTYLGDTANSDDVLSKLPGLLDIHTVLGFKGGAYGLVEAHAKMNPKSYYYAFDYKGLYTTYDIANGASIIPGGIAHVDDLLYLFQLIPLLTAKDWAVSERYVKYWVNFATYGNPNGPGDIDEPFPRYNAADHRFLIINETDKVGYHCRDTWIGNSLELVSQTLARNITTMTTLRFVLAVLCLGTFAKAQEWNYTWAWTPPTLPPEWTDWTPGSEFPTLPPDVTLVPPEWIEDAKVEIPVLGKIQGAVSFTSPVTAPNKRKFYWFAGIPYADPSSYVGQESRFKPSRLWEGPLPTNNNGVFSAINPLIWCPQGDILPLSTDLGDVLTSYKNHSKVKSARMSEGISPQIQGIEACLRVNINTPVNPENGQTAQRLPVIFFIHGGSFDMIWGGIFGGHRFLNRDVVLVTINYRLGILGSLNLGIDDAPGNAAMYDVVTSLKWVKKYIHHFGGDPDKVTVTGHSAGAVMASHLLTSPLSIDDDGKPLVHGIITLSGSALSQWATATDPMTHHLRVAYYTGCYKNNTDESPDLKAIRDCMAGMEIVDLMDAMDKYTDNERWEARLGFDAKVPSLQNPELTIPKFMIETPYAVIEKGEQLDIPLMMGATRHDGTFVMEDTYNKFLEKHNYTTNPIYLRNELIPTLLTALVTLFLLSLFTLLCEGLQDDSGELIHSIAKHYIGEALYADDFESKIPGLIDIHSVFAFKAGSYKMIEMHAKKNPNSYYYSFEYQGLWTVDGGDVIPGGVGHIDSIYYLFQAFPLIVPADQNVAYRFVDYWANFATYGNPNGEGPKTVAAPYNPLNHAYLVIDSFDRTGYYCRDSWVNNSLEIMPTSPTSSPITVGETNNLIDENIYMGRPTIHENNKTDALKKSTIFILVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNN3</accession>
    <name>A0A1D2MNN3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000803">
        <property type="protein sequence ID" value="ODM94455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNN3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="133" mass="15511" checksum="2179E8651DAEB633" modified="2016-11-30" version="1">MGRRKEVHKKACARFVCTRESCGKSWISMHSWKQYLEYCEDCGKEAVTVNIKDQKLDLDNFDCPSCGEFWQSLHDAEETGRQCFCGNYVYSSGGQKRFGRHYWLECVKGCGSKWEDHNTDREFGQRCTNVGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP21</accession>
    <name>A0A1D2MP21_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Threonine--tRNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000756">
        <property type="protein sequence ID" value="ODM94763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP21"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="11282" checksum="2E322B7BAD6793D8" modified="2016-11-30" version="1">MQNPMKGNLPPLVDVQLQDYFAVGAECPTLTQIFSERGLIPNPPEGNKLEWMLENFVTDADIDSCLHDPSNSTSYLDNNGIWVNANDKLEYKIRLEEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP93</accession>
    <name>A0A1D2MP93_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Craniofacial development protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Bucentaur</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11914</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000756">
        <property type="protein sequence ID" value="ODM94758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP93"/>
    <dbReference type="STRING" id="48709.A0A1D2MP93"/>
    <dbReference type="OMA" id="LDWAAYV"/>
    <dbReference type="OrthoDB" id="445677at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="251"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00019033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="336" mass="37576" checksum="1B2EE0C539DB4848" modified="2016-11-30" version="1">MEDEKEDRNEGSEGSDDDSDDEDFVPTTSDANKANELSEEDDDEEDGGDAESPGKTKSGKKKGRNAKSKKRKLGKGGSKTGKRRKMEDSDTDDDEDIDFVLNESRRKDVEVEDQPRQEDTAAQDEIEKKQTDLLWADFLTSVNEEKAKKGKERTVEKVVSKVYDFAGQKVEVQEKVRVTVSESTSKAGESSSTAKSITEKDKSSPEESTATPGTSTSSSPGPSTNGKQPYQPRRGGISILGNDPEAIGLDELEKRGLSGLLKAFQSKTKKIGTLEKSKLDWEEYKRKQGMEEELHNHTRSRDTFIDKQEFLQRADYRQFEIEKGMRATARSRRLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPD2</accession>
    <name>A0A1D2MPD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multiple coagulation factor deficiency protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11733</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000731">
        <property type="protein sequence ID" value="ODM94950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPD2"/>
    <dbReference type="STRING" id="48709.A0A1D2MPD2"/>
    <dbReference type="OrthoDB" id="289247at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057020">
        <property type="entry name" value="EF-hand_FSTL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052110">
        <property type="entry name" value="MCFD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23104:SF17">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23104">
        <property type="entry name" value="MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23564">
        <property type="entry name" value="EF-hand_FSTL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-related protein 1 EF-hand" evidence="5">
        <location>
            <begin position="115"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25651" checksum="F2F6FBAB43FB36D1" modified="2016-11-30" version="1">MTMSNATKILRNVNSRLLYSTGEHCSFYTLPAHSIHIQPTVFNSLSKLKFYTSKLYLKKAIMSGLNQIAVFLFVFLITTISVICHEQPNPFMEPSSKINHSYNPRNKLLNPVGERKHIMEHMEVTQNTSTMNEDELQFHYFKMWDLDHNNKLDGCELMNVVIHQEGHGSDHNNSTDNALIKILKDEELSILIDPILHDHDEDQDGMIDYYEYMLALDYANSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQW6</accession>
    <name>A0A1D2MQW6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase TIC 32, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000700">
        <property type="protein sequence ID" value="ODM95194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQW6"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="114" mass="12647" checksum="F7F74EA16E9F85CC" modified="2016-11-30" version="1">MKRICRTTDGAANTVLYPVLTPEVGEKCGGEYFETGKVQTTNPQANRPEIQKRLWERSLQLTHDANANSSQNQEYGRRTDEVVVMTGGSNGIGVSIVKKLLQLDYTIILGMKCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR88</accession>
    <name>A0A1D2MR88_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000684">
        <property type="protein sequence ID" value="ODM95324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR88"/>
    <dbReference type="OMA" id="ADEGNHW"/>
    <dbReference type="OrthoDB" id="3219649at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904425" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="147" mass="15449" checksum="AB9EA677DA3EC181" modified="2016-11-30" version="1">MMKLALVVALLACIGCASAVTHAEALRRFQAVGVTVTSSGGCSDRNKPTCTSFDSARENTVAGLVTLKTASGCVINVTGGTETGHASGTYSHWNGYKADISLNTCINNYVTGHFAYIGVRGDGAPMYQSAAGNIYAKEGNHWDILYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS79</accession>
    <name>A0A1D2MS79_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000624">
        <property type="protein sequence ID" value="ODM95758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS79"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904467" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="42" mass="4366" checksum="068228AE86DFB365" modified="2016-11-30" version="1">MKIFGIIATFVAFVCVVGANPLDAPKKEANEALASGRGTDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU24</accession>
    <name>A0A1D2MU24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transient receptor potential-gamma protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000540">
        <property type="protein sequence ID" value="ODM96432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU24"/>
    <dbReference type="STRING" id="48709.A0A1D2MU24"/>
    <dbReference type="OrthoDB" id="2373987at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="73" mass="8620" checksum="420F9EEFB8F11492" modified="2016-11-30" version="1">MWKKQDLDLLTPNWQMSYGRNDDEARGRVKSHSITGMMNEDFNRPHQQITQLTLDEKKFLLAVERGDVATTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUL0</accession>
    <name>A0A1D2MUL0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protocadherin Fat 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_10173</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000534">
        <property type="protein sequence ID" value="ODM96504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MUL0"/>
    <dbReference type="OMA" id="TDNDHGK"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060429">
        <property type="term" value="P:epithelium development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000020">
        <property type="entry name" value="Dachsous cadherin-related 1b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000015">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000021">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000066">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000053">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026">
        <property type="entry name" value="FAT ATYPICAL CADHERIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026:SF136">
        <property type="entry name" value="PROTOCADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="125"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="256"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="364"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="488"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="640"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="757"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="901"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1008"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1113"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1288"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1539"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1615"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1740"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1840"/>
            <end position="1959"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1970"/>
            <end position="2054"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="2057"/>
            <end position="2157"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="2158"/>
            <end position="2258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="858"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1230"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="873"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1238"/>
            <end position="1258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM96504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2310" mass="256905" checksum="15E1EDEED5841234" modified="2016-11-30" version="1">MVETDIRVGFIFLKKQAGRPVEIGVTPKSLPEWNDHWSIDPITGVLSPTRPLIGSQSSSSSGKDQDRDDSNANNNNSNREILRVRAKNRWNPSPLAGSVATVNIHIRPVNRYAPQIRINRPPQVEIRPYGLIYAIVSIRDPDEGENGIVDLEIKEGDPNGVFRVSPTSTRNEFYVEMSPIVAANFHWNPDKLFNYNLTLKATDRGSPVKTSEKDLQVRLADVLWSSISAASSSSFFSPSSSFSLSSSVGANGAIFEKDVYEVEISETAPPHSVVFRLRRPEPKVLLTISSGNEGQDFYLEETSGVLYTSKWLDAETKSTYTLTIDSRDRRPNRIGDLSRRRQSVAKIIVKITDGNDNDPEFETANNPTQVSLMENEPVGTKVAKISARDRDQGENGYVTYNIANLKPVPFSIDHFSGDIRTAKSFDFEVDRREFQLLIRASDWGQPSRRQSQTTLNINLIDANDNRPLFTVTECFAVIDRSIKFEMEIGKLEAIDFDRNDVVSYRMVSGNEDSCFQMDSHTGKIKVMCDLRDVRSTKRNLNVTATDGEYFSDVMTIKVELWDSIKNNFTKQDTIKSGIKLFSTAQSIFECRDTGVQERFDRMAALSEKNNQKDDIEFGGENGFPLVPSRYGENVHTPSFVDLPAEITVNESTHVGTTVLKLRGRDLDKGYNGLLTFVISNGDEAHGAWDIFNDESLTATGSFSQEANLILAVPLDREDISEYVLNVTVWDQGKPAKYSSKLLTIKVLDNNDCKPVFTKTAMKIKIGEGSELIGEQLLQVTAYDDDEPDTPNSAVSYKLLNELPEFSIEEKTGIIRLMRDLDRERQDLYELLVVAEDGGTPKLSSIAIVTIQVDDKNDCPPRFESFSQPTMMTSSASSQGGSPQQKQQQQGYQSNIGMLSPSSSTRLVKIMEDWPVGGVVTQVIAKDDDLGLGGIVRYSLMDGDENADFSIDEISGVVRVKKELDYEKTSIYNLTIRARDMGTPPLFTDSFLVVEVYDVVEQELSISFTDFVAQANISENAPIGTVVTTVSLVPSDSPFYFSGGLVLFLEGESRSFFTVDNQGLIRTAHNLDHETHPSHWLTVVARSVSSGKVLARLECFVKVLDVNECHPLTTLPSYTIEIPENVPSSTSLIRLEAFDCDPGTSGSLHFSLKTSTPYFEIHPESGEIITTEFPLDREKQSVHIFDVIVTDSGLPPLNSTSQVIVKLQDENDQRPKFLYTRGIRYIPELINELQRDEPTDGENSLEESSEDEEEDEDEELSKWSDWMVLEESNTDELTNMAEGGSWKKIYRVVAHDGDAGENGTIRYRLKYRANPEITAADETFSIHPVTGEIYTTSSSLKADTVLKFLIEASDGGLPTPLVAETELVLRVKSVNRGPSEPPKILLAMKNHVVSLTTKERAGYTVETIDAEDPDGDDLWYEIVSGDPDLYFNMWPESEKLILARPIPMAKEFRLNISVSDGSNVVFTQLLVKVIESERASSLIWEKSNYTGIISELVSDFTPVTTLRVVSEFEYHHHHPSGANHNWTKSTTSSTAGNSVGTILYGFHNAEDSRSLEIFSIDTLSGLVSIARPGLIDRESLPRHILTVKARDPIHFYMFTRLTILIEDSNDHAPDWRYSVTELRVPETTAVGSLISQIEAFDMDSGENGRLSYAITFGNIGATFGIDKNTGWLQLDRPLSIPFGETLVEYQLTIQASDHGKPPLSSTTNLNILVTLASDEEVVALRCSGDGTLASRNSPFSSSKMMRVRVKENSAPGTYVTTVRAINSKAVSFEIEDNRNHMFWIDPTTGVILVGKGRGILDRESKASHEIFVKATNSRGATATCRVVVDIIDVNDHKPQFTKLYYEGIIREDSPLGTLVRKRPEIAEFDEKRPLVLESSDNDVGLNAVITYSMVEDEDMRTVFHIDPSTGALLLVTSLDYEKRSHYFFHVKATDGGGLVSPTVATVNVSVENVNMKKPVVQSARVEMLVPTAPGVLIHQVLATDADGDSLDFNITRGNAQEFFKIGKRTGEIRIGKADGFSGSKHVLEVAVTDGRFWSLATITVHVRQLVRNPEFTFRNTTFFGSVTENSTKSVNIMSLTVVGSHMNERLRFQILNPNLHFGIKRTSGVIFTTGKKLDREEEPTHNLLVEVHGDDPSRVARSFVTINVADINDNAPQFMNLPYVAVVSMEAKPGDPVIQIKAYDADEGENAMIRYELVRSPHGDIYDLDRHSGVIRLRRRPDGVGHHEITIKAYDGGVPTCTTETTVLVKVVSSDQPVFEQQWYETWIPEDAAVGSTALALVAHAKNPILYSIEGGNELDEFGIDYQTGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUV4</accession>
    <name>A0A1D2MUV4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Doublecortin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000493">
        <property type="protein sequence ID" value="ODM96879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUV4"/>
    <dbReference type="OrthoDB" id="47802at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.230">
        <property type="entry name" value="Doublecortin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003533">
        <property type="entry name" value="Doublecortin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036572">
        <property type="entry name" value="Doublecortin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03607">
        <property type="entry name" value="DCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89837">
        <property type="entry name" value="Doublecortin (DC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50309">
        <property type="entry name" value="DC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Doublecortin" evidence="2">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="908" mass="105016" checksum="EE5A4153D23B1E59" modified="2016-11-30" version="1">MEARYLTDLEWRICHAVNIYVYRNGRDGEQPILVHIPPSKKKNMRTVMNVVQERVKYPVGYAKFLYKMDGTRIKDPCELEMYNNYVVASNFEKHFKCAAYGRKRSPLLVLNRESKHVRVLKLQNQNYYEWLLKKKNVGEERPPYIYPAIYSNENYGPQDLPLGQMGNYHPPNVEAPGCCYPRVDGGNKTYRVDGQNKYVVNTVTVDVTPDLAGMNVPRERRSHRHGNKRHSKYRGKFLEQTPSDMLNANVLTADSASQEGASVVTSETEEQLKIAKKIRASKHKKTKSHRVHMVTSEEYHEKQCVNVIESTTTQSQTSEDTRKLQKSMRKAKREKERLMFTEPSAPPPPPAQFRDNTDYNNNAQQQVIRQHPDTHCYKEEILKYVDRAIHNSNGSVAPTQKTFYYSPEKLAEINSCGNIQQFELAFTQPQQTGNPAGQWTLIQQQPHQQQMFQQVYAIESQPTTVYPVQTLDPSSINSQRPQPQSEVINSYPPPPQHPPVIQNIQLPPSFQNMHNPVPVMHAISSQPIFHQPNPQPQCVVIPNNTALAPTQQQIQPPQMPANVNMTSSPQLLTLQNHNNSQSQLQQVYQLGIVQQPNPQTCIQVDAKAMRQYVDNQKLLENRYSPVVNPFEGQKEELQQQGHRVHRQEKHRTSRYKQRHHSDQTESELDIPFTPLKTYRLNNNQMPPPNYIRNQNDNDSYDRCQNPCRQKPERLPVKVKSRNVAIQMGYPGASARSVRGANFPESHAGSSIDIPFLQDRRNLIFNPRDYSNLSLMERTPRSGRGLYERFLTPSKDRTLRRGNNFGSSYSDQYVNLRSSRNHRYPISVNSLIRPEHLVVDKPSEPNLDELVTIPPPNEFRELEAVHFSRHNNPRHQSNMFSRRNNAYYCTNNNNERSESTSQYMHSRYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV98</accession>
    <name>A0A1D2MV98_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000500">
        <property type="protein sequence ID" value="ODM96818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV98"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="14336" checksum="DDD2C95EC72177D9" modified="2016-11-30" version="1">MWARIHGGFIPTLLEVRVEMDVVPSHFYQLLAVWFVFANNLVRHPPQLSWGYRELREMKIGNPASLEYQNFTSAFLFIIVGFFPGGVIGRACYNNSVSTKERSGTIRFSRNAVLAERMAFLCFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVY7</accession>
    <name>A0A1D2MVY7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcobalamin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000460">
        <property type="protein sequence ID" value="ODM97240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVY7"/>
    <dbReference type="OMA" id="QELCINL"/>
    <dbReference type="OrthoDB" id="10378185at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904625" evidence="1">
        <location>
            <begin position="25"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="122" mass="13585" checksum="4DBC95FDEF562D57" modified="2016-11-30" version="1">MVKSYLIFAIIAAVLCLLFAQSHAFSVELYDQKHFKGQSTTVEVNRGCADVPDEWDDLASSILPKDCIIIYKHPDCQGPRVRLEPFTFGSAYLKEINFEDKISSISPCNVQSTPAPKTVTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX34</accession>
    <name>A0A1D2MX34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative cation-transporting ATPase 13A3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_09159</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000435">
        <property type="protein sequence ID" value="ODM97522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX34"/>
    <dbReference type="STRING" id="48709.A0A1D2MX34"/>
    <dbReference type="OMA" id="GMAACHS"/>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000026">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000045">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="645"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="695"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="808"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="701"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM97522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="827" mass="90813" checksum="A0C05ED75E10DB01" modified="2016-11-30" version="1" fragment="single">TGTLTEEGLDLWGAVPTTTGTGMGSNYETIYPSLATSPGFLPAVRHVNHLPNGPLLVGMAACHSLTRIDDDLIGDPLDLKMFEWTGWELEEPGVADNEKYDMVTPTIVRPGTAEVNDNVPSTKSRNSVGTDYEVGVVRQFPFSSSLQRMSVITKRPGEREFELYCKGSPEMIVSLSTPESVPENFTATLERYTQHGYRVIAMASRTLQQNYAKAQRVVREEVETGLTFLGLIVLENRLKPETTAAISVHKNAGIRTIMVTGDNMLTAISVARECRMIEQQEKVIVITTEADKTGTEAKDSERQTLFYSYATKAGAADSEGTQSPVSVGSGCGSIMEQTLINVEPPANRYVFAITGNAFSVAKNFYPEILPRILVRGAVFARMNPDQKQQLVEHLQALGYFVAMCGDGANDCGALKAAHAGISLSEAESSVASPFTSKEANITCVPNLIREGRAALVTSFGIFKYMAIYSLTQFISVIVLYTIGSNLADKQFLYIDLFLISVFAFTFGHTEPCPGPLVKQPPSANLVSVPPIVSIIAHMITILGTQLLSFKYVQQQPWFTPYIVKEDEYASYENYAVFSVSAFQYIIMAVVFSQGSPYRKGFWTNKYLMLALVGLTTLTGYIVLYPDSWVIGQLELQLPPSMEFRLTLIGFIVCNFVIAVLIEQGIVNFLLSKRRSNKPPAAKHGYLQIDQELSSREDWPPVSSTPNGSVKGSSTDFSKRKLILSADTKSRTLERPTLTKVNANEEDGVTRRGTRRHSSSVSIPIPMADYVGLQPQFLPASNNQHPYSLSVDNSDSIAAHINNTLNNANLNNKGSHSDCHIPPPQYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX40</accession>
    <name>A0A1D2MX40_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Neprilysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09185</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000437">
        <property type="protein sequence ID" value="ODM97501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX40"/>
    <dbReference type="STRING" id="48709.A0A1D2MX40"/>
    <dbReference type="OMA" id="NIWCESI"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF237">
        <property type="entry name" value="NEPRILYSIN-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="94"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="550"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="760" mass="84458" checksum="EFCF8196F49661FB" modified="2016-11-30" version="1">MRNSSVMGRVASVAVLTAFVLLATTSTTPTLGASLLHQKSSNYNQKLEAIRELSKAAGAPQIDGSVNQEEICLTEGCLDAALDILNAINMTVDPCKDFFQYSCGRWLANNPVPPSASRWSRFNRLRDEVNNVTQEILNEEPNDQDAKPINQVKDFYKSCIDIDAIEVVGLEPLNQVITEFGGWQLLNPGVWNSSAFDWLKSVAEVRRRSLQSVILSVYVSADLKNTTRSAVYLDQPGFGLPRGVLITPENYTALITAYENYMVEVAQELGTSQTEAQLRTSAKAIIELEVAMAKISSSDEARYDIDRIYNPYALNEYQTITDGVDTEFSIVWKNYLDQVFSSSGVAITDNEFTIVNELEYIRNLIPILKGAEADTIANYIVWRLVSGLIPDTNAAMRAIVFKFQQALTGATVPSTRDVTCANAANGVFGMAIGVKYIEAVFDDDAKAEVNTLVENLRLSFKEMVTDADWMQDETKTEAIAKADAIRSFMAYPDWLENKTAVEEFYQGLELADTYFNSQLNLALYRMDKGLKGLREPTNRDEWIMYPGVVNAAYSPELNSITFPAGILQPPFFGKLRPKSQNYGGIGVVIGHEITHGFDNQGAQFDKDGNFNNWWDDVTKVEYDARAQCMSDQYSGFFAEAAGLNVNGDLTLGENIADNGGLRESYRAYQKYVEENGQEGRLPGLEHLSTNQLFFLGYANIWCESITPEGLVNQILTDPHSPAEFRVKGPVRNNAEFAAAFSCPEDENGMNPPEEDECTVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXD1</accession>
    <name>A0A1D2MXD1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000419">
        <property type="protein sequence ID" value="ODM97697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXD1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904705" evidence="1">
        <location>
            <begin position="26"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="12761" checksum="7239F96DAFA2D43B" modified="2016-11-30" version="1">MLFVLDSKAALLACFLVLFAAKSYAAPSPCSGGFDNLSNNTSRLNCPHHHGHHHHQICGTCPEGMQREVVQSPYCGTCLIIPINCDDGHFKNEMGHCETCPCLKPHEERRCLFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXI1</accession>
    <name>A0A1D2MXI1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000437">
        <property type="protein sequence ID" value="ODM97504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXI1"/>
    <dbReference type="OMA" id="NSHHLYQ"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904696" evidence="1">
        <location>
            <begin position="24"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="409" mass="47590" checksum="5F5F888E28AC9749" modified="2016-11-30" version="1">MWDSRLLLLNLPAIFLLTWEVRGEVEICTDGGTHVFQITHDTCPFGFVFLEPQTADCVDPYDGDLKKQFQVFPALSTDPIEPGNSCKTIMSSMCTMPIQKVSAHFFRQRPDASDFAIADELQDKNYGGMKDQTMRLFEYMFDLGNQEMDESLRVVQLLKQTYRIFKKFCDPAFVKTEFYEDVEKAFIFLLNEADSTRVKDISFEEYKIIHSHLQQCEDQRNPLKFEGRRCATYSLIQRVNKSGEVFTRFHEGNKEAFTKYDVPVEATWGAIDFVHGLCYGTFRDHINSHHLYQQALERIFTNEILFRWKSRFVLTEQHVWNNFFSANVKNALINMDICIQASYLSTPFLHRLERPIEQEDDRKAAKGRKKRWAEVQSLTSFGDIDGYCFQTADEASKTIQNLTNSCPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXM8</accession>
    <name>A0A1D2MXM8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Elongation of very long chain fatty acids protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000432">
        <property type="protein sequence ID" value="ODM97554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXM8"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="48" mass="5689" checksum="025BAEAB9AE168B1" modified="2016-11-30" version="1">MYPYFALRAIGIKIPSYVANFITTIQFSQMLIGFGVNITSWYLQRKYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXR0</accession>
    <name>A0A1D2MXR0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sphingosine kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08922</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000413">
        <property type="protein sequence ID" value="ODM97758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXR0"/>
    <dbReference type="STRING" id="48709.A0A1D2MXR0"/>
    <dbReference type="OMA" id="TMGNFYA"/>
    <dbReference type="OrthoDB" id="3853857at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF112">
        <property type="entry name" value="LD11247P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="5">
        <location>
            <begin position="29"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="365" mass="39773" checksum="283B0412F5056FC6" modified="2016-11-30" version="1">MTVANESQDTLDHDPKLGHSTLSLASYLLFVRRYLVIVNPVSGQGKGLPTFREKVHPILMEAGVKVELLVTERPGHARSMVSSSNLSEIDGIITVGGDGLLYEVVNGLRCRDDSDRISNIPLGIIATGSGNGLARSVAEYSKEDADYLKNPVLSTTLAAARGKVVPVNLMEVELDGRKIYSFLSVGWGLLADIDVESEVLRAIGESRFTIWSFLRLAKLRHYKAQLSYIPCERVSRDELNGTSRTSLRERDPVFIDGEFISVYSTCQSYIGSDLIFAPKAQPGDGLIHLTYMTKDAGRASATQFLLGIDKGAHLSVSGVSYVTVKEFTIRCAGGINGTITIDGERVTGEEIKIKISPRPLHVFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXV3</accession>
    <name>A0A1D2MXV3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lon protease 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000409">
        <property type="protein sequence ID" value="ODM97808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXV3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="252" mass="27805" checksum="975231C16CB30080" modified="2016-11-30" version="1">MDPLMRQIRMLKLKLYEASDEVKKQKSFANVVEGTLKDLKEQLRLSQEQSAARLKEREIELEKIIVKALMDKHEGEERNNLLNEEIAALKTALAKMTDSQKITEAKYRSLLDEIEKAAKSISCNEIEDVNNGNNPQHLINALEFETQAYAGGPSTSTSASVAQSEPLAIRDGAKSSGSDDGGVLAEFLGMNGGEPNVVPMSSRNLRMRTSTADKQEKACSGCPQAAKVDRGMKRKAPDGEEERMKHGEDNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYU6</accession>
    <name>A0A1D2MYU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Actin, muscle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08523</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000377">
        <property type="protein sequence ID" value="ODM98158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYU6"/>
    <dbReference type="STRING" id="48709.A0A1D2MYU6"/>
    <dbReference type="OMA" id="PVWGGYP"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000218">
        <property type="entry name" value="actin, alpha sarcomeric/skeletal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="368" mass="40848" checksum="6788370A74780FC8" modified="2016-11-30" version="1">MSETPIVVIDNGGNTVKAGIAGDDHPSAVIPTGVGLQEFFNLSDLDTFNRYMEITSSGDLKVRNPISHGAVTNWEDMETIWRHVIQDNLHINPEEASILMTEPMANPKPAREKIGEILFESLNFNAISIATAPILPMYAAGRTTGIVVDVGDGITQVVPVWGGYPITQAMERIDFGGRDITQFFSREQLNRQNQKLPHEVFKLLKEKTCHIVLDYDQATEKSSSSTTFQLPNGDQIEVGEEAFKCPEFLFNPMKFEESEATKLGLHQLVYKAIMKTNIDVRKDLYANIVLSGGSTLFPGFVERLEAELKKLAPSSVKIKIVAHPARKYFSWIGGSVLASLTSFPDTLITKQSWEEGSGRAALHKMYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYX4</accession>
    <name>A0A1D2MYX4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000371">
        <property type="protein sequence ID" value="ODM98239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYX4"/>
    <dbReference type="OMA" id="HGQISTH"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904755" description="Ig-like domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="26555" checksum="2BF3B9D3884CADBE" modified="2016-11-30" version="1">MSYLWISLSVVILAFHDFTRNGAAHAQGATPAKVDVPTVHSTVGNEAKLLCSLSEENNETSSSSTSASPLRYCVWERVDPASSSSQTTLILNFNDINSQPGIFSGVSGYSYQGEGFREGECGVKIATVKTEDIAKWQCTLITDEKVFRGYVMLEKEEPPKKNETVGSAVAARTAIDDGNQFQTQSSFRPRPIITSYEDARAIIQPEIIVQSTSSDGSPLIQEVKVESAGLQIKPRRGGKLIVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N023</accession>
    <name>A0A1D2N023_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000337">
        <property type="protein sequence ID" value="ODM98647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N023"/>
    <dbReference type="OMA" id="ECEMDEF"/>
    <dbReference type="OrthoDB" id="6756251at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34239">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34239:SF2">
        <property type="entry name" value="TRANSPOSABLE ELEMENT P TRANSPOSASE_THAP9 CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="407" mass="45906" checksum="D6054549525375D4" modified="2016-11-30" version="1">MGGHRSSERQRSRHRSLRPSHHDRRERRRRRTPLSRSPTRSRSPRRSFSKQKQSDDGVMSLILSKLNMLENRLNERDSRTPSMRRRSSSRSSSGSTSSVSDTINTASGTKNQTTADSKSQATTDASGQKPTDPSSQKSADTVGQKSTDPPEKDIVVTGTDENELIIDAPFDQELLDILGAAPVTDHKWGESIPDELAVRWKHFSTKGIEKEARKALFDSYEIPSNCTFLLPPKLNPELNSKNEAIQKKEIVFRKMQEQLGHALAAFGKSITLISKSQWEGKKDAFESLVNGAKMLTDIHHSLSASRQHTILFSVQQNIKKVLEECEMDEFLFGSDLGNRLKTAKELEKVSNEVRISQPKPQPKRKSQPKPQSAGRKEVPLNSKGPVRQQVTRRYGATKPEKRSYRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N099</accession>
    <name>A0A1D2N099_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 13 member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000349">
        <property type="protein sequence ID" value="ODM98494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N099"/>
    <dbReference type="STRING" id="48709.A0A1D2N099"/>
    <dbReference type="OMA" id="ILLWMTT"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015137">
        <property type="term" value="F:citrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015141">
        <property type="term" value="F:succinate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF82">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="507"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="629"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="677" mass="76558" checksum="CB18F985D41362BA" modified="2016-11-30" version="1" fragment="single">CFEVTFSVRFGVKIELVCFCLQKEKSAFLLGKMIKLRNIFVNWEFFLIVFLPVVLMPLLFIPDDDLLHNDRPSTKFKCAYVVILMAVYWMVEALPLAVTSLMPMVLFPLLGIQDTGLYTKNVHSFVFIGDLKMYVLCLGVQFHDPSISEVPNYCHHSNLALKNGFIELKQNAKLVLCCRVSKNYMKETNMMFVGGLMIALAVEFCNLHRRIALKVMTTVGCSPVRLTLGVMLTTTFLSMWINNTATAAMVIPITIAVLDEIYPPREQQSSTRKRRPSVFREKSDADLPFLAVKYSHHPKNKPIRQMNAQGKMVIVDPSETARFIPSGEANAIDIDVDVSQNGKYLDMSFATWMVYNIPPMAINVALCWVYLVVYYIGVPDRMCFWRKYNEKRRLEQEEETQKQKVVAKVLEEKYKALGPMTFHEIAVFTLFILIVLLWLFREPRFMSGWSDYIAKVDIGDSTAAILVVLLLFIIPRDLNAFLGRGEHANNPVKVPALLEWKYIQHSLPWGVVFLMGGGFALSDGAVYSGLSHWLGRQLSYLDALPKEWILIIVMVLAAGCTEVASNSATVNVFLPMLIALSESLQIHPLYLTVPVTVTCSYAFLLPVATPPNALVFQGAGGDITIPEMLKVMIFPNIMCLIILFFFHISYGTLLFNFGDYEYESFNMTAATMLTSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0L0</accession>
    <name>A0A1D2N0L0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peritrophin-48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000324">
        <property type="protein sequence ID" value="ODM98770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0L0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="14208" checksum="649E4B06247F2ECC" modified="2016-11-30" version="1">MDNDGLRTDLCDNSSTVLSVFNYCQNFAECHKGIAIVRSCHERDVFSPIKRKCVEPKEFECKLKCTKRHNSVFMDPFDPNLYYACLGGELETFECDPGVKFILDKQQCNNTIVYNPTNTTSKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0V4</accession>
    <name>A0A1D2N0V4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein spaetzle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000312">
        <property type="protein sequence ID" value="ODM98902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0V4"/>
    <dbReference type="STRING" id="48709.A0A1D2N0V4"/>
    <dbReference type="OMA" id="RIETCKY"/>
    <dbReference type="OrthoDB" id="6359065at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005121">
        <property type="term" value="F:Toll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0021556">
        <property type="term" value="P:central nervous system formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032104">
        <property type="entry name" value="Spaetzle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052444">
        <property type="entry name" value="Spz/Toll_ligand-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199:SF12">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16077">
        <property type="entry name" value="Spaetzle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Spaetzle" evidence="5">
        <location>
            <begin position="200"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="299" mass="34092" checksum="558BB5B47E54E13E" modified="2016-11-30" version="1" fragment="single">ALRLPNGRDGILAISLALAAILVQIIDGERFHPVAPQRPTKPDPIDPTGRGSPGIVIVYKKNGKFPFSPTPPPPPHAHHSLDNVVDLICTSAPLTIFPVDRPPQSHQNSYYPPSNNYDDYHHHHPPPPSHHHGKYKPTCAGSGDSYCLYDQEYPMDKVSNIAQHYQNQLQPLYEEMNHYSLSDYISHDNATHRYRHKGHFICESDVSYVRPGWAKNWKGEWVAVLNTDVFPQSVRIETCKYPKKKCEYMPPCYKSYCVQRYTYVKLICLDPYNPGKRPTTDVFEIPSACSCFVESFPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N155</accession>
    <name>A0A1D2N155_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA replication complex GINS protein PSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_07736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GINS2/PSF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000309">
        <property type="protein sequence ID" value="ODM98941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N155"/>
    <dbReference type="STRING" id="48709.A0A1D2N155"/>
    <dbReference type="OMA" id="WFELEEM"/>
    <dbReference type="OrthoDB" id="1938138at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11712">
        <property type="entry name" value="GINS_A_psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21694">
        <property type="entry name" value="GINS_B_Psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1020:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.50:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007257">
        <property type="entry name" value="GINS_Psf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056784">
        <property type="entry name" value="PSF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25005">
        <property type="entry name" value="PSF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028998">
        <property type="entry name" value="GINS_Psf2_subgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF2 N-terminal" evidence="7">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="6">
        <location>
            <begin position="67"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR028998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="22420" checksum="AB3BC0B9F8FB1C87" modified="2016-11-30" version="1">MTLTAEELEYIAQEEEVEIMPRVEIPTMWLITGDVGPFEVGMPIKIPLWIALQLRGDNKCNIIAPYWLTKSSMEKVKEFETKSPLFSKMPSKHYMSIAKLIFELCPEDVPEADAIKLLIKDVWDCRMAKLQTAIALFIEKGASWAKVDNLTQMEMCAIRPFFPHSLGHIHRLRKTIQAARLHSAGNASVEVRGKLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1S0</accession>
    <name>A0A1D2N1S0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sulfite oxidase</fullName>
            <ecNumber evidence="7">1.8.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_07450</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Energy metabolism; sulfur metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.1" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000293">
        <property type="protein sequence ID" value="ODM99236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1S0"/>
    <dbReference type="STRING" id="48709.A0A1D2N1S0"/>
    <dbReference type="OMA" id="TWHVAEL"/>
    <dbReference type="OrthoDB" id="10051395at2759"/>
    <dbReference type="UniPathway" id="UPA00096"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02111">
        <property type="entry name" value="eukary_SO_Moco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.650:FF:000002">
        <property type="entry name" value="sulfite oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000002">
        <property type="entry name" value="sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022407">
        <property type="entry name" value="OxRdtase_Mopterin_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00559">
        <property type="entry name" value="MOLYBDOPTERIN_EUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="16">
        <location>
            <begin position="111"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00070338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM99236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="572" mass="64436" checksum="EE81BBA8415D83DF" modified="2016-11-30" version="1">MKTILCSSYRVCSPLVLPSWYTSVGVETNFYYDRRNARESQRRKFHQSREYHGQSRNSKNNLELSRLGGTIGALTIAGYLAWKKSTSNVAQLDAKKTPHETGKHDQVLKHLPHFSRNQVAEHYDDSRRIWVSFRRGVYDVTEFVAVHPGGSRILMAAGGSLEPFWELYPVHQKSDVFQILEKYRIGNLNEEDVVEAQEAVDHFKGEPMRHPALIRRADKPFNGETPPSLLTEKFHTPNDVFYVRNHLPVPQVDAKTYRLEIDGINLTETTFSLQDIKKFPKVSISATIQCGGNRRTEMGKDKVVAGLGWTGGAIGNAKWTGARLVDVLRSAGFKPEAYKHAKQLHVKFDGLDTDQSGECYGASVPLSYLLDGNFDAILAYEMNDKPIPIDHGFPVRIVLPGIVGARSVKWLSRVSISEEESQSPWQQRDYKVFSPSVSLETVDFSAAPPIMDTPVTSYICSHNNGDKVKKGPVKLQGYAFSGGGRGIVRVEISLDKGKTWNVARISDTANLESTKNWSWVLWEANVNIQANAEIWVKAVDSGYNQQPEDFNNIWNYRGLLSTAYHKIYLEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Q0</accession>
    <name>A0A1D2N3Q0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06773</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP = 3',5'-cyclic GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13665"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57746"/>
            <dbReference type="EC" id="4.6.1.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000247">
        <property type="protein sequence ID" value="ODM99906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Q0"/>
    <dbReference type="STRING" id="48709.A0A1D2N3Q0"/>
    <dbReference type="OrthoDB" id="1890790at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF462">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="16360" checksum="779B38D246580AC2" modified="2016-11-30" version="1">MWGMRYLHSSLVRVHGFLTSYNCVIDARWVLKITDYGILSIYHTQGLTLPPRSSKVCLQETVDETVCMLLSIIQTFSHLLYQHQMVELLWTAPELLRDESLRRHGTQAGDVYSFAIIMQEVLVRGEPYCMLTLSPEGIIYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4A4</accession>
    <name>A0A1D2N4A4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="32">Protein deacetylase HDAC6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="33">Tubulin-lysine deacetylase HDAC6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="37" type="ORF">Ocin01_06615</name>
    </gene>
    <organism evidence="37 38">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="37 38" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="37">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="31">
            <text>N(6)-acetyl-L-lysyl-[alpha-tubulin] + H2O = L-lysyl-[alpha-tubulin] + acetate</text>
            <dbReference type="Rhea" id="RHEA:21548"/>
            <dbReference type="Rhea" id="RHEA-COMP:11278"/>
            <dbReference type="Rhea" id="RHEA-COMP:11279"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="31">
            <dbReference type="Rhea" id="RHEA:21549"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="30">
            <text>N(6)-acetyl-L-lysyl-[protein] + H2O = L-lysyl-[protein] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58108"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="30">
            <dbReference type="Rhea" id="RHEA:58109"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell projection</location>
            <location evidence="7">Axon</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cell projection</location>
            <location evidence="4">Dendrite</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
            <location evidence="5">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Perikaryon</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="37">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4A4"/>
    <dbReference type="STRING" id="48709.A0A1D2N4A4"/>
    <dbReference type="OMA" id="HTRSHVN"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043204">
        <property type="term" value="C:perikaryon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051646">
        <property type="term" value="P:mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051129">
        <property type="term" value="P:negative regulation of cellular component organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032886">
        <property type="term" value="P:regulation of microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10002">
        <property type="entry name" value="HDAC10_HDAC6-dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10003">
        <property type="entry name" value="HDAC6-dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000342">
        <property type="entry name" value="Histone deacetylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000005">
        <property type="entry name" value="histone deacetylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF38">
        <property type="entry name" value="HISTONE DEACETYLASE 6, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="25" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="28" id="KW-0966">Cell projection</keyword>
    <keyword evidence="22" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="26" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0488">Methylation</keyword>
    <keyword evidence="27" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="38" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0678">Repressor</keyword>
    <keyword evidence="24" id="KW-0804">Transcription</keyword>
    <keyword evidence="23" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="21" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="18" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="20" id="KW-0862">Zinc</keyword>
    <keyword evidence="17 34" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="36">
        <location>
            <begin position="1059"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="35">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="35">
        <location>
            <begin position="981"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="35">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00048287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00049136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00050910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00068733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="ARBA" id="ARBA00082852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="35">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="36">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="37">
        <source>
            <dbReference type="EMBL" id="ODN00062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="38">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1161" mass="128129" checksum="487DF2D8DD3C0644" modified="2016-11-30" version="1">MSDFKPVDGETQPSISLSRKLSGEGDKPILIPLNANAIGNRCNSSNSNLEDAQRNSSSSTVFKDPNGNHPNPEDHGATSMKKRSKRPTAKPSPAILLAKQNAQQGKKRTSQTDIQIMMTDHLQPARDAKDNVRKPTGVVYDLKMLQHYCLYDPKYPECPDRLSSIIYRCEQLGLLARSKHIEPRLATKDEILSVHTEDHIENLKRICETQEGTVEELERHASQYDGVYFHPSTYGLSLLAAGSTIDLVNAVLDGRIQNGMAIIRPPGHHAMKSEYCGYCYFNNVAIAAKRALEMGKATRVLIVDFDVHHGQATQQMFYDDPRVLYFSTHRFEHGTFWPNLEESNFNYIGSSDGVGFNCNVPLNKTGMGNSDFLSIWHQLLLPLAYQFNPDLVIVSAGYDAALGCFEFAPDLVLVSAGFDSALGDEKGEMEVTPQCYPHLVSPLMGLANGKLAIILEGGYCLKSLAEGAALTLKTLLGDSCPKIDATKCPTYEAAESVLNATYMLRSKWSMLIGQTHVQEGEQIIAQTQKKLHIPEAKYIWTEPLPEVYETRNCYPEQSSNVQKQLDERISQLILTTDLQQPPHRVAIVYDDLMLKHRNVAEPGHPERPERISNIFACHGDFGLLERCHRLQPREATEDELLLVHTEDHVRKMKGTQNMSGRDLYKFKENFNSIYFNNHSYQCALVAAGSILQVVDAVVDGSCRSGVAVVRPPGHHAETDEPCGFCLFNNVALAAKYAQTDHGLKRILILDWDVHHGNGIQHIFEDDPRVLYISIHRYDHGGFFPCSSDADYNVVGVGAGEGFNVNIPWNRKGMGDTEYLAAFLNVVMPIAYEYNPELVFISAGFDAAKGDPLGGCKVTPEGYAHMTHMLSSLANGRVVVALEGGYNLTAIAYSMTLCTKALLGDPIPPLQLKEEVDSVAIESICDVMHTQAEYWSVLKPFRKYFPFNTELVPVGSYSKIGVSSIESSLGKLNIKKKVTSPVRSQHPIMDHENNEIPASDATAGASSSSSRIETLELIGATAGAVGGSQSESLAEVITKMQEVVSDKDEQMPGVIVQPSDTCPHFDNISSVPDGGVDVNALCVDCNNKGENWICLTCYKVYCSRYVKGHMVEHAGQSGHKIAMSFADLSVWCYECDDYIEHPNCRAPKSAAHLSKFGNALPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4P1</accession>
    <name>A0A1D2N4P1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000224">
        <property type="protein sequence ID" value="ODN00202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N4P1"/>
    <dbReference type="OMA" id="ATETICD"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1266"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1343"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="656"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="686"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="812"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="862"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="945"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="963"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1349"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1381" mass="150677" checksum="E31177CE5BA04839" modified="2016-11-30" version="1">MIFDMGVKNETDELRKLMVWRTGMHGCGRTLLINHPMTLDRWKDGKRWGNVQLILLITSGLLLQGGCHAQGSGGSNFFYYYSPTQRTHVSQTFGQSAQAQVNSYFNHIPTNRSPLIGYPPLESTSIQPNPPQQQYVYRTPAGTTYSPLPSLSQLSLGLQQQSFPNYQAPQDESQNTASTTSFSTFSRFGKDAFSNQAQLPPSPQPLLTNRFQSTIQPQSRGTYSFFESPFQYIHQRQLEQTQSPVTTPAPVVVTSTSAPNIANTFLGADEGEAVRRKPKFSSRFRYVEPQVNPYSQVNSYSSDLPYTERRFYSTVIPSAPTPTGYSFSIGSEDGSGPKASVHVSMGPLSNTQHLTEITRSQFLRPPQSFGARNKLAPEVINSKGQSVVFQLTREKTGESSSTTPATAFVEPLSEVLQNFADPNTTSTVETLIKEPSVQTETIASPKSELPRKLDDINIPQRIIKRKKVARNRLQLNVTEGTGVENAPQGRRRISPNRVPETQKEVNDLPKGSQAVAIPSSTESQNQLDSISNNEQQEFASHTPAEENFPLLSSSTTSSTLDVPPSPVQTPFTEATPSTQDNEQANPESEQKQDEYYEYENTNSDSQPDKDAENLATEDEAPIPILRGVSKEDYPGVFNDNSLETERGEILTRHKTSQPAISTASTQSSSAPDSSEGQSQGLPSVDSEPASPSTSTTTEQVATVAVSTSTSTTEQVPSDYQEQAPTLLHDDSAESSPPQEVEHAQVTPEPSTTTTTTTTTTELPELEAPHHEIIEGIQPVNKEVDTEAILAQDISQQNTGSSTTPGAINDVQSTTEHTTSTSPPEDISSTSESGAQSVDQQQLPPSDDNSQRNDAELEGEVGASQSSTTEATSTSTEIVNVSTTESEGDDFSSYSQEELPDEEHELDEVSSDEEIGKAQRLALQETLTRLRNKQKSTDETSSSSSVDAQGVSNVNGTVEENSNARRRSRYFRRKPLQLANLTLPTSGPLPNQNALFEDDDVDHSRSQVIEKIQKFRANVRRVSSTTTKRPRRVTRPSSDRVVKKVKLDQVDSFSNSSSAGVDPYIPRRTSPKPYYDTSTTTTESLPRTRIPLPDTTTIPTTTTEEAQTEMSPFPPTTTTTTDAPAPVNRIMVPTTEATTITTTESTTTQTPRTLPSTTSSTTTDAAEEFYSDDYELDQVQEPKLIPYDVDTLSTTPSITPSTTPSTTPSEDVYFTTTTPVTTSTTTTTFTTTTVTTDELSTGQLIIHEILPTQPPLKEVSFIVGESVEDEEGSKSLEDSQSDESQGQPPVATVVRVEANVEVSSSVSKPEPITNVSNEAVHTEISDDAKGTQPGKKVRVVVVRQRKVNTSKKVSSSSTSSSGGGARRRRKIARLITNATRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5E4</accession>
    <name>A0A1D2N5E4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-rRNA-processing protein TSR2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_06224</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in 20S pre-rRNA processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0220 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000206">
        <property type="protein sequence ID" value="ODN00451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5E4"/>
    <dbReference type="STRING" id="48709.A0A1D2N5E4"/>
    <dbReference type="OrthoDB" id="268928at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007919">
        <property type="entry name" value="UPF0220"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13180">
        <property type="entry name" value="SMALL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05255">
        <property type="entry name" value="UPF0220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="106"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN00451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="355" mass="38853" checksum="526214DE37112911" modified="2016-11-30" version="1">MLTIDYRSYSALAIENGQGGGYGKDIAAWMCQAVEDFFYQNDDLDGDEVSEFIGTMMNQELDTIVDDNSLEVLGQELVQHFKLASSGKQQELQTLFAKLDEVAAKPKPKASCTKEDDSDDESEDDEEMEVDDDTASSSQGTSNDPNSSANAGPSHHKTGKNFVSDPDDDGWVTFALGSILHETFEVLIWRRPKRRYKTKMSGILDSARCDCLEGERRNSIAAAVAGALFFTGWWIIIDVAAQGPGSDQFEGSYYVCGVFGTIALFMINSVSNGQLRGDAFTDGCMGPRGARLWLFTGLVLGFASLIAAGWILFAGYVLNDSGADKWYGVAVFLQNLFIFGSSLVYKFGRSEDLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5T5</accession>
    <name>A0A1D2N5T5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_06355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000214">
        <property type="protein sequence ID" value="ODN00316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5T5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="7125" checksum="3A6D53A02A0FEC5E" modified="2016-11-30" version="1" fragment="single">NILLLIITTFDDHSKKSGFIKWAEDKRKEREMKCFNKFTGNNIPNSNPCLLRNKFPTLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5Y8</accession>
    <name>A0A1D2N5Y8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coenzyme Q-binding protein COQ10 A, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06018</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000193">
        <property type="protein sequence ID" value="ODN00664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5Y8"/>
    <dbReference type="STRING" id="48709.A0A1D2N5Y8"/>
    <dbReference type="OMA" id="VKAECVD"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="4">
        <location>
            <begin position="54"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="216" mass="24339" checksum="94DE0A1E8D0C7E07" modified="2016-11-30" version="1">MLCLRHQPVVSHHGSWRMITNCIQQANFLSFPGGSSTATKRKQFTERRIMGFGMEQMFDVIQDVEKYQDFLPWCHSSVVTSKGKGFLKGNLVVGIPPFVESYTSNVTLVRPLIIKAESTKGKLFKELTFGNPQSCIIDYNVSLEFRSTIASQAANVFFNQVVRAMTEAFYNEAKKRYGPESVPSRKLKLSEAVVTAAMMTLREVQEEANTINLLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6M6</accession>
    <name>A0A1D2N6M6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 11</fullName>
            <shortName evidence="5">U3 snoRNA-associated protein 11</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UTP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000196">
        <property type="protein sequence ID" value="ODN00626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6M6"/>
    <dbReference type="STRING" id="48709.A0A1D2N6M6"/>
    <dbReference type="OMA" id="DLKYVVM"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="30084" checksum="70323D36D2E6C88C" modified="2016-11-30" version="1">MSSWKNASKAYQKPHRERHQPEARKHLGLLEKKKDYKERAEDYNAKKAQLQYLQRKALDKNPDEFYFHMVNSEVKDGVHFDKTKEVTMTTEQVKLMQTQDHRYIASRHVIEEKKVKSLQARLHNLDSDHPNKHTFFVDDEKELRKFSLTKRLDTPAELLHRRYNRLRNTDVANKNFQALAKDAETLKNVAKLRHKAYKELEARTGRNKKLATLERKIEIKKVLQDKSRTVKSRLAPETPDSAPVYVWKSERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6S1</accession>
    <name>A0A1D2N6S1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Desumoylating isopeptidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05709</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000179">
        <property type="protein sequence ID" value="ODN00954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6S1"/>
    <dbReference type="STRING" id="48709.A0A1D2N6S1"/>
    <dbReference type="OMA" id="VYWTKPG"/>
    <dbReference type="OrthoDB" id="412286at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="9"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="224" mass="24770" checksum="9CD79729C42E33A3" modified="2016-11-30" version="1">MAQSEEHREPVLLNIYDMYWTNQYTSMMGLGVFHSGIEVYGTEYAYGGHPFAFTGIFQITPRDSEELGEHYKYKESILLGYTSFTKEEVEQAVSHLGRDFKGINYHLMNKNCNHFSSELSQLLCGREIPTWVNRLAYMSTCVPFLEKCLPKEWLTPAALEETVKLASGLGDNAMEGQSASNHISASSSNGSLTSPLNNASGGALSSKRKDSRSSTQGLLRAGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8D4</accession>
    <name>A0A1D2N8D4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="3 10">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Gamma-ECS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 10">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05163</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glutamate--cysteine ligase type 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="3 10"/>
    <dbReference type="EMBL" id="LJIJ01000148">
        <property type="protein sequence ID" value="ODN01523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8D4"/>
    <dbReference type="STRING" id="48709.A0A1D2N8D4"/>
    <dbReference type="OMA" id="IAHMFIR"/>
    <dbReference type="OrthoDB" id="7939818at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000007">
        <property type="entry name" value="Glutamate--cysteine ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000002">
        <property type="entry name" value="Glutamate--cysteine ligase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004308">
        <property type="entry name" value="GCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164:SF0">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03074">
        <property type="entry name" value="GCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="697" mass="80110" checksum="1968E3200FF750B4" modified="2016-11-30" version="1" fragment="single">SGLNISNNNALQRILHKRSHGRTILHIGAYLLKPYVFIFLETSNVSSQYKWKLEQLVAWKEVLRITETDIHFFVKPLYISDWFLPKFDSLGGMGLLSEGSPLTWEETKKWAKHVKSNGIQQFINSYHRLKDRQGDSLKWGDEVEYIIVKFDDETKTTKVSLRANELLPILRQPEYDSPETVKSLWRPEYGAYMIEGTPGTPYGALPVHLNVVEANMKSRRKEAQLLLPPNEMVLSIANFPRLGSPGFTFPVYNPAPESSVSRSRFFPDEAIFPGHPRFQTLTRNIRSRRGNKIDIQVPIFKDKNTPTPFVEPGVPEQKPDMIYMDAMGFGMGCCCLQVTFQACNIDEARKLYDQLTPLCPIMLALTAATPFYRGYVSDVDCRWDIIAGSVDCRFPEERIKIPKSRYDSVDSYLSEENEEYNDIPLIYEQEHYDALLKGGIDRHLAMHVAHLFIRDPVSLFSEKIHQDNTKDSDHFENIQSTNWQTMRFKPPPPESSIGWRVEFRPCEVQLTDFENAAVVCFVVLLTRVVLSYNLCFVIPISKVDENMKIAQKRNAVLEQKFWFRNDIQNKGNKSYSLMTVDEIMNGKPQGFPGLIPLVQNYLNSMDVDADSQCTLQQYLSLLSRRATGEVDTAAKWMRDFVTKHSAYKHDSVISDEINYDLLRRIGRLPHETCTKLLGNIDPTKTKTKDDVPDIFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8D8</accession>
    <name>A0A1D2N8D8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette sub-family B member 6, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05191</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000149">
        <property type="protein sequence ID" value="ODN01497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8D8"/>
    <dbReference type="STRING" id="48709.A0A1D2N8D8"/>
    <dbReference type="OMA" id="SWDYGNL"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015439">
        <property type="term" value="F:ABC-type heme transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000287">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="20"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="238"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="501" mass="56409" checksum="8C6E83171546BBC8" modified="2016-11-30" version="1">MRLDMDDEQRKLEIFIRMHLDRGTESIASTLEHLIYSVFPTIADIIIAMLFLSWKFGWVYGVIVGIQIVLYLILTAYIIEKRSKYQSGINAAENDLRQKVVESLLNFETVKSFGNEKYEKQRYSHALRTLHHRQNRVGITSSILQLSQLLVINSGLLGISLILVYAIVNDRQLSPGDYVLCTSYLAQLYGPLNYLGGYYRELRVNLIDAEYMLEYFNHKPGIIDSPTAYDLKVTDGAIKFCDVSLSNDCGEIILQNVSFSVAPNTTVALVGHSGSGKTSIIRLLLRLLDASSGKIFVDGANIKDVTQSSLRDSISIVPQDTILFNDTIRNNLRYGKLTATDYEVILAAKAAQIHDKIMSLPDGYDTIVGERGAKLSGGERGRVAISRALLRDSRIIILDEATSALDSTTEKEIFDSLKYLCRNRTCVMITHRLAPVVDVDCIFVLKKGQIVETGRHSQLLERNGLYASMWKQQSKSESKETFHHEDKSLFIHKRALSNRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8P9</accession>
    <name>A0A1D2N8P9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gamma-aminobutyric acid receptor subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8P9"/>
    <dbReference type="STRING" id="48709.A0A1D2N8P9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="3">
        <location>
            <begin position="39"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="449" mass="50679" checksum="044B4E735E3DEC42" modified="2016-11-30" version="1">MHMKMVKRNKLISVIYFLFVIFVIKTKAASGRKHASLSDILDDLDLRSDNRVRPGYGEGALEIHAFAHIRNIISMNEIDSTITVSLLLKQIWIDPRLAYPDRNISEILIDNSNFMSRLWTPDTFIVNEVRTHCWDDRSLAHQIIRLTPDVGHKTDEIVYLWRNGSKSVDYSSSLKSLVGKSYSLVSAETHSQQSFISTGGSYSKLTLRLQFAKLWLRSFITFFLPSTSLTICSLLGLWIIREKYAVAGIVLNFSIAGFVIFMGILAYSQMPLVAVLTPVDVHLGICLSTIFSSVTFHALVLCLRIISHQKGRYIGRSVTSRKVFHSSSSSSSQKLQSQVGPKGHYKTNADGVVDDVDTEDGEREYSDDAEAPSYYVTAQEHDGKQTLRGINECDSSEETHQEDTKRSSITKTKRFLTLLLRVSLAGSKWTVLLSFVIAESYFWYVYVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA22</accession>
    <name>A0A1D2NA22_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF243 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA22"/>
    <dbReference type="STRING" id="48709.A0A1D2NA22"/>
    <dbReference type="OrthoDB" id="8030796at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040003">
        <property type="term" value="P:chitin-based cuticle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004145">
        <property type="entry name" value="DUF243"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31927">
        <property type="entry name" value="FI07246P-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31927:SF16">
        <property type="entry name" value="LP07342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03103">
        <property type="entry name" value="DUF243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00690">
        <property type="entry name" value="DM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="DUF243" evidence="3">
        <location>
            <begin position="112"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="257" mass="25399" checksum="E066CD749025BC9B" modified="2016-11-30" version="1" fragment="single">VYKRTTEFISASVSQLPTVLSTAISKFLKTFKLYIFFNMKLFIVLVCTVATAFAEGGYSGGGSSFGSIGGGFLSGGGGGFSSGGFSSGGFSSGGSGFSNGGGGGGGAGGAGGQVHRHIYIHTAPDDAVDSQARVIRVPGGQDKHVNIIFVKAPSSSSQQQTEVILPEQNEQKTLVYVLLKKGEANSDIKDPHQPDLLSLRYKNGGSDGGAGGAGGSSGSGIGGGFGGGSSFGSSGSSFGSGSSFGSSRGVSSAYGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAL3</accession>
    <name>A0A1D2NAL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mite group 2 allergen Gly d 2.02</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAL3"/>
    <dbReference type="STRING" id="48709.A0A1D2NAL3"/>
    <dbReference type="OMA" id="TEMPCTI"/>
    <dbReference type="OrthoDB" id="6489092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905299" evidence="1">
        <location>
            <begin position="28"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="2">
        <location>
            <begin position="36"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="159" mass="17395" checksum="59C97AF58BCF2CF1" modified="2016-11-30" version="1">MKSVIPILSCLLAVAIILSCNVGELEAGVVTNYEIDTNCAQDIIVYELRITDCTEMPCTIRRGKRYTIEGDIGVLRNVTNPMLKCSSVYLGRHIDLPGHGGCPNLTNGTCPMVVGERYTTATSFKLPYYVPPMLYTAYCSMVDDEGENLICGWGSGRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC83</accession>
    <name>A0A1D2NC83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">High mobility group protein DSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03794</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMGB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC83"/>
    <dbReference type="STRING" id="48709.A0A1D2NC83"/>
    <dbReference type="OMA" id="CAYAFFV"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21978">
        <property type="entry name" value="HMG-box_HMGB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000006">
        <property type="entry name" value="High mobility group protein B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF32">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="101"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="101"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="157"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="23506" checksum="D5F9C10754678D66" modified="2016-11-30" version="1">MPRNKVPGKPRGRMTAYAYFVQACREELKKRHPDQAVAFTEFSRSCAQRWKAMSAQEKAPFQNQAEVDKQRFNAEMRTYVPQDAGRKRGGKRKRSKDPNAPKRSLSAFFWFCNDERPKIRGMNPEYTVGDVAKELGRMWAGVDPQTRERYNLMAERDKQRYQREMEGYKNNKKTAARAPPIPAPQYEAEESEEESEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCB6</accession>
    <name>A0A1D2NCB6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protease serine 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03784</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NCB6"/>
    <dbReference type="OMA" id="INCAREG"/>
    <dbReference type="OrthoDB" id="8114044at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000028">
        <property type="entry name" value="Serine protease easter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905362" evidence="5">
        <location>
            <begin position="24"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="120"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="463"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="1100"/>
            <end position="1364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1367" mass="152347" checksum="88737165645BC772" modified="2016-11-30" version="1">MARKASFATILINILITLKVILGEQQSGDGWQLEVGHIPAGGVIRVADDETKSDMIPDPMLEVWSNPPISLEQIFTHPNYRYLSPLTECGYSSVEVVDYDVNEDETLPKTSDAETRRKRIVGGQPVIGQKHPWMAQIYLLNISSGEYWFHCGGTLISNSTVLIAAHCLTRIDPGTSLGMVVLGQADKRNVKFCKTEKPEENCSRNYIRHIEDYQVHYGYSEGDLINDIGLIYLRKPPELDQFVYILIQSSSILAQSQTNGCWLGLNGCGLRWPESNASKTSGTGLTKTFTLQQIPYQNICVGGNTGKATCNGDSGSGILKTLDVPLLDNKEQRVFQFGIVSAGGHVTDTCGNQGRPAIVTNVIHFVTWILNHIVPGALSYQWTKAGTKEGSWIKHKTNEGMFARKVQQLEELQYKNEFSTGKNVDVSSHPNLYLLPTFQHCGNLNTEDSVFKDETLPKRVKRVVGGIPTTAERYLPWMAQVYVRNVATNKLVLRCSGTLISCRHILTTAACVTEIPPPFVFDSIIVGQYNRNSSEECINEVCYSPVKLKVKDIIVHAEFEKYTYKNNIALVRLSQDVIFTRLIQPICLPQREALIDGMNVHRYFSAGWGKIFRETVGENVYNKLSEILLQMYVDILPRKDCNFVYSRQIGLLDRSGICGIGKSSSTGECSGDSGSPLMKKMEVDPTHFLQNKVFQLGIVSYTDCGLEGMPTTFYLIFPFVLIAVLNCLSLVQGECTAKLEERCNYTEDCCLGSCTAGYCNDGLYKNNRDRSVVADFSELIAAELSTGQNMDVSEHPNIGILPSYDECGFPAPGPRRQKRIVGGRPFELGKYPWAVALHLNVIQDDSSYFSCGASLITKRHILTADVAIIRLKHEVNFTDFIRPICLPRTEDNIKNWPDGSLTVIGWGTQNTASDEGPKKVSYRAQEVENFLVHRSNCDRFYTRNIGHLRRSHICAGGYPGKGDCAGDSGGPLFKRIQIDGEDGSEERYFLFGLVSTGAVINCAREGKPSVYTSVLNYMPWILDNLEKKPTAVGENIDHKKFPINPTDEFSTGMNPPVDLTKHKAAALLPKFPDCGPIFGQQDHKRFPSRSNHTQHRVKRIVGGISQSVGTYPWMVQLYSRHVTTTDLNLRCGGFLISKRYVLTGAHCVGDVRGSYVIDGVVLGNFNRLESRECIDDKCNDMVIIPIEDFVAHEKLSKYSREYDVAVVKLSRDVEFNRFIQPICLPLAEEMVKKAWPPGDLKYTAAGWGRVDANSNEAVMSNVLIAMNSTLESKKYCESVLTRRVGRLEHSRVCAGGSRPGKGECVGDTGGPMMRWATMKGPDGKEATRMYAFGILSIVECAHQGIPSLYQNLLYHMPWVMDQLEYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCB9</accession>
    <name>A0A1D2NCB9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_03939</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Complex I is composed of 45 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000097">
        <property type="protein sequence ID" value="ODN02735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCB9"/>
    <dbReference type="STRING" id="48709.A0A1D2NCB9"/>
    <dbReference type="OMA" id="EHITGHY"/>
    <dbReference type="OrthoDB" id="6241903at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026627">
        <property type="entry name" value="NDUFB2_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15223:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15223">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14813">
        <property type="entry name" value="NADH_B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="13" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="12555" checksum="24BB445810B0CE15" modified="2016-11-30" version="1">MIVSRLVPLAVRSSAAIKTVGINQQRLISTSLPRLSGGAWSYRSFTPPDRKFVIWAEAAGAFMWWWIFWHLFTDYEHITGHYAFPDIDAWTDEELGIPPDNADDPEYIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCQ9</accession>
    <name>A0A1D2NCQ9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03626</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="6">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000088">
        <property type="protein sequence ID" value="ODN03044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCQ9"/>
    <dbReference type="STRING" id="48709.A0A1D2NCQ9"/>
    <dbReference type="OMA" id="FALMETP"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032509">
        <property type="term" value="P:endosome transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000005">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF233">
        <property type="entry name" value="ANNEXIN B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0041">Annexin</keyword>
    <keyword evidence="3 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 6" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="317"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="382"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="411" mass="45180" checksum="0F71FE2127513018" modified="2016-11-30" version="1">MGFYTTGSSGTVSGPADYDAEAASKKLYEGMKGLGTDENVIVEVISSHTNEQRQEIKDKYKTMYGKDLVEDLETELGGSFAKIVLGLMKLPEEYIVESINQAISGLGTDEYALIGLLCTRTNDELDEIKKAYKEKFEKEMEEDVAEDLSGEFRSLVVGIINGGRDESEEVDSDKVKEDAKNLLEASEGAGTREEVFQSIFNQRSYEHMRQVFEAYKELAEGKEIEELIESEFSGSLQAAYMALVKIFKNVAEFYAERLKVAIKGAGTDDETLIRIIVDLKDIIDSYESKADSKLVDDIVSDTSGDYKLILEKLVTQSEAEVEEEVTATNAGDMDETVPPEAEGEEKAEGEGEEGGDEEKKEGDDEEKKEDGEEEKADDAEEAKEGGDEEKAADGEDGAAGEEDGKASKDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDM9</accession>
    <name>A0A1D2NDM9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein eS28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000077">
        <property type="protein sequence ID" value="ODN03351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDM9"/>
    <dbReference type="STRING" id="48709.A0A1D2NDM9"/>
    <dbReference type="OMA" id="SCSIIHN"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN03351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="65" mass="7402" checksum="19CF11F0C1F816DC" modified="2016-11-30" version="1">MEKPVVLARVTKILGRTGSQGQCTQVKVEFLGEQNRQIIRNVKGPVREGDILTLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE16</accession>
    <name>A0A1D2NE16_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase RNF13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03189</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE16"/>
    <dbReference type="STRING" id="48709.A0A1D2NE16"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905426" evidence="7">
        <location>
            <begin position="30"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="286"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="336"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="499"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="408"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="574" mass="63523" checksum="68B2BDC6A795667B" modified="2016-11-30" version="1">MGPFARLSAARYTCIVLILSITTIVQTEGRIVVLSAFDDETVYVVREKAVVENTDSPSKGMLILSMPVNACKPVVPSPPIPINATGTSLKATTDNATTALESVGNDSFGWILLVSWSPENDCSLRTKAEHAINAGYAAILLQDPSAFEIESEPLSPLSALTATTVFDYGWTDVGIYACTIDPEDWNILRRNFTNDDYYLSFEDSSSMSGWFTYFIVGVLAIGAVFFTIGLSYVLVQLLVLILLWIRESIVSRIQQVRRDRRRRLPASQLRKIPIQQWNSDMLQDICSICLETFIVHDRVRILPCSHVFHQACLDPWLLKHRRKCPNCKRKIVFPDENRESDSSSEDERTPLLRRGSSRRESETRVSRQPDVVSQRVQTQNHQPLVSGIHRYLPPSTTASNNVSNSTTEVGDTSANPQLPSHDSSINTSTEVDTTSQNGDQPDLKDTVDHLCARMESVGRKIKKKVKAHQASKLENDSSSDLSTGIQPVLVAVTIESNNIPDTSDNEYPHTESQSHFSQQPSSSNNNAISNQCSTGGLEVKVVPEFIPSPSHTLTNSENCNNEHGESSISSDLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE47</accession>
    <name>A0A1D2NE47_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000076">
        <property type="protein sequence ID" value="ODN03375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE47"/>
    <dbReference type="STRING" id="48709.A0A1D2NE47"/>
    <dbReference type="OrthoDB" id="72772at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="234"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="305" mass="35292" checksum="3A498C10CC337D1C" modified="2016-11-30" version="1" fragment="single">VRLRNLVQLIGVNLDANDNSELYFTLHVTPLSAPFFTSERIPKKAGQRVYQWKEIEPEHAYYSGIKFSAKGCTVRIWAKTADGNCDAVLNWGVYFEGLQRLGSQNDWSSDMFEDGVILFRTPFGVFTVESCIKPRPTSLTRYLVISKPAAEVRPSYKCKLLASLHRKQRAIIEEVELAIDLKSECEILAFTETGNVPGNDRRLILSSRGRKIRPGSKKAQLSLKKEIDEVRFKVLSLVEEKGRAEGRLQRMKKERMGLEEMNRDMFQRVEALNNERRRLQQFKITLIEKRHKLSQLRTDVFLRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEG0</accession>
    <name>A0A1D2NEG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative chitinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000072">
        <property type="protein sequence ID" value="ODN03485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEG0"/>
    <dbReference type="STRING" id="48709.A0A1D2NEG0"/>
    <dbReference type="OMA" id="VACCDPS"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="59"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="157"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="217"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="284" mass="31502" checksum="1277A3F3D81A3D43" modified="2016-11-30" version="1" fragment="single">DGQKPTGAQSGYLSLFIRFNPKIDRRVKVIMEHSKIFFGVWLIASLFSAILADRGPVNFYDCSGRPDGNYQHPSDCTRFMSCVAQQYAYELDCPAGLNYDEANDRCDWPSAVGCTIDSPTTTTEEPTTTEEPTTTTTTTEEPTTTTEEPTTTTEPPIFDCSGLEDGNYPHPDDCAKFVSCVAGKYLYIRDCPADLHYDPRNDRCEYQWLAGCDSSLTTTEEPTTTTEEPTTNTEEPTTTTEEPTTTTTTEPPIFDCSGLEDGNYPHPDDCAKFVLASLENILYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NER2</accession>
    <name>A0A1D2NER2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucuronosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132367"/>
            <dbReference type="ChEBI" id="CHEBI:132368"/>
            <dbReference type="EC" id="2.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.17" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000065">
        <property type="protein sequence ID" value="ODN03744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NER2"/>
    <dbReference type="STRING" id="48709.A0A1D2NER2"/>
    <dbReference type="OMA" id="NHAYDAT"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000021">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN03744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="515" mass="59390" checksum="3C8B0C674B2CD635" modified="2016-11-30" version="1">MKISSENILFYGIVGSYSQRISTWPLIEALSDKGHNVTYISAYDSKDPHPKIYDYAPKKWKETMGPWEGYKTFYEVRKNKQMLNMWFELPSLGLLACESLYSDPEFMKWVKSSSFDLIVVDGLMNECAYGLVQLYKSKLIIYGSSSVMGWYYAYGLPDETASVTECMFNFPPGKEMSFLQRFVNGMSPLVWQVLREYWYFPKLEEVTKKALDLDVLPPFSEIERGANLLMLTSHYSLDYARSLPPHVVNVGGMTSLRKAEPVSKKLEDFINKGKNGFIYVSFGTVAEFVNFDKHVQEEFIKAIQSFPNMQFIWKSTYDVNATLPSHVMVTNWAPQLSLLAHPKIKAFITHSGMGSTVEAIHFEVPLISFPVLAEQDFNANTVASRNAGIKLEILTLKQEELEHAISEILENPKYRNAMKKLSKISKDRPTSALENAVWWTEYILRHPDSNEYLHPPSIQQSWWVKRQIDVWFFAAMLVILLPSLLIYGLFRLCRKLVYSIVSISRKNTNYRKKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFI4</accession>
    <name>A0A1D2NFI4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aquaporin AQPAn.G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02833</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000061">
        <property type="protein sequence ID" value="ODN03845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFI4"/>
    <dbReference type="STRING" id="48709.A0A1D2NFI4"/>
    <dbReference type="OMA" id="RISKTIW"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="189" mass="19573" checksum="002F7B97BB92CA28" modified="2016-11-30" version="1">MTAIGHISGGHINPAVTLGVLVSGKMSVIRGVLYMIAQFLGGIVGAALLMAVTPNSSTGTVENVNWPIAHLGANGLQPGVTAVQGLIVEAMVTFILVLVVYGCCDARRDDVKGSIPLAIGLTVTLSHLLSIPYTGAGLNPARTLGPAIMTGKFDDLWVYFIGPWLGGAIAGVLYTVLFKAKLATPTEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFR7</accession>
    <name>A0A1D2NFR7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02619</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TMEM43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFR7"/>
    <dbReference type="STRING" id="48709.A0A1D2NFR7"/>
    <dbReference type="OMA" id="NMMALDE"/>
    <dbReference type="OrthoDB" id="410725at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012430">
        <property type="entry name" value="TMEM43_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07787">
        <property type="entry name" value="TMEM43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="348" mass="39590" checksum="C0535C79CC1430A9" modified="2016-11-30" version="1">MRAIEGTKAYTEGLRSVFPLVTPDFVLKENEGKLVHMVGYLRIPEPLEDAFYGVSITAVKLKRRVQMYQWVEEEISSNSEEIQLHNSSHKYSKMWRDKLIDSSKFHDTLNHENPFFIPVSSQILMNPYVYIGKFALGKEFKDKFKTFIQFTGGERPESLDIKMHMGLYYHSSDLWNPSVGDLRIQFSFAGPTGSFVSIVAKQSGSELKPFYTESGAQIAFLHEGKKSHTEIFVKEHALVTLYAWIIRLVSVLAVVFGSWLSSKTITLLNRRNQVVQNLMSVGPMRFSLIIAVFLSNSTVGLAWIPHTPLFGILMITFASCLLLYYALVGDNITNNKPMTALPQYSQMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFU1</accession>
    <name>A0A1D2NFU1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein trunk</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFU1"/>
    <dbReference type="OrthoDB" id="5950649at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052876">
        <property type="entry name" value="Insect_Hormone_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39940">
        <property type="entry name" value="PROTHORACICOTROPIC HORMONE, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39940:SF1">
        <property type="entry name" value="PROTHORACICOTROPIC HORMONE, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905499" evidence="1">
        <location>
            <begin position="33"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="239" mass="27183" checksum="20B04E241C60BCBB" modified="2016-11-30" version="1">MSTFRVEPKLILLPILVIVVFNTVGVPRGAHSQDTQAEDRDDLIEARLPPRQIPLPQQWVAHHFQHSRFSGPMMKNDGNERKKKDCGFPVLARRLFGAVLKRSDPHLATSEEEMEVKIKEEDNSLERVKRSELSESHSGGCVAKRQWIDMGKDYYPRYVKSYHCSSTTCDRGFGALGECKPKHYTTKVLKQITPVDTTYVEDCDQSLPESLRLDWKLISVTVTTCCDCVSPVSRMFGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGX5</accession>
    <name>A0A1D2NGX5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ras-related protein Rab</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02214</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The small GTPases Rab are key regulators in vesicle trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGX5"/>
    <dbReference type="STRING" id="48709.A0A1D2NGX5"/>
    <dbReference type="OMA" id="FCKEGGF"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045335">
        <property type="term" value="C:phagocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090385">
        <property type="term" value="P:phagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04107">
        <property type="entry name" value="Rab32_Rab38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000222">
        <property type="entry name" value="RAB32, member RAS oncogene family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030697">
        <property type="entry name" value="Rab29/Rab38/Rab32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF39">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="234" mass="26395" checksum="6D5BA27BEA1C51C4" modified="2016-11-30" version="1">MVFGTAKQDKEIRNLILFEKTFKKGLLLCCTHPSIVNMSSSSGKKERLYKVLVVGELGAGKTSIIKRYVHQFFSQHYRATIGVDFALKVLRWDPDTVVRLQLWDIAGQERFGSMTRVYYKEAVGAFVVFDVTRSATLEAVPKWKADLDAKVALPDGRPIPTVLLANKSDQPKEGIAANREKMNEFCQQQGFSAWFETSAKDNINIDESANFLVSKILEMDKWSQEPLAPDRGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH46</accession>
    <name>A0A1D2NH46_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inactive pancreatic lipase-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02362</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH46"/>
    <dbReference type="OMA" id="CGHARAP"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00707">
        <property type="entry name" value="Pancreat_lipase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033906">
        <property type="entry name" value="Lipase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905561" evidence="5">
        <location>
            <begin position="23"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="6">
        <location>
            <begin position="50"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="6">
        <location>
            <begin position="263"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="383" mass="42966" checksum="EBC1ED244B194B81" modified="2016-11-30" version="1">MNTHKLLACIFLVSISISGSSSQFTFGDRVTFQGATGPSNPGYRLISRDPRDIKYFLFHRRLDPDAFIELHLGDTSFFNSSTFRRDRPVKFLIHGFNNNGTGTRFPIDTKNAYLENSEHNVIVVDWGKLSTPAVPRRSQADVFYPVVVDNVPMVGENIAKFILFLLDNGMISSLSQVHIIGFSLGAHVSGYAGAYIRQKRQATVSRITGLDPAGPMFSRVPDDGRLDRTDAEFVGRQSGLSLTILDPLECPFSMRRVMNVIHSSRLGLYDDIGHVDFYPNGGRYQFNCIKLSDYDNPFQTFRSFARSLSNAVGSCGHARAPEYFTYSIRQGPEKVLACKCLSWRDYLTACKSTCSDKTTFGEYCPPTARGKYFLEINIRDGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHL2</accession>
    <name>A0A1D2NHL2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHL2"/>
    <dbReference type="OMA" id="FDDYINV"/>
    <dbReference type="OrthoDB" id="10555139at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="73986" checksum="93C2F4AC39B2BE41" modified="2016-11-30" version="1">MNEKQLRLMIIFLLVHKRDPKLMPGERAVQFKLCARVYFTFCASILTCQFFFVTRILNRKGIAHFVLDFSQGCLRLRYAIEKLFAQSLYCDTYCIVKRNHLCYRNYLRSTGQRQGDSRQQWLAGESKRCCLDENSLIYRAASMDCTPEQETGFRWDRKPHPMCIPHVVDCILAYLKVCDLKSCRLVSSQYNEIACKALQREETIIFKTIPQLETYLSNIKPISLPFLPSSLLTKSQASSASPLLSEEGSINYGIEIEWPAIRNHNQHHEYSQQQWSSYADSVTNPYRYSHRSFHFDYCDPDTEIEQIDHFFSTFGSQIHRLKYTTDLLPYNFPRSLGHMGEIWKGRLCNLEELILEMKWGIPAHLFANTEVAHRHQVLLPRLKSLHLDVLLTDRDADRAELFLRQLLSITPNIEEISIPGSKRFFDDYINVVLARVIISSELRKLSTLNFCLALSDTQMRLLTGKNLPLSTLILDLEDLQFDGGAENNGEGNNDNVDFENMDQDNNEDDLQQNGLHPDNNNEDGMRHEFLRQNQNRRPSFTPIVKSTLQRFLNSLSATLSSLHICFPQNPRNSLHTLTFQQEMTELKFLALGYFAGSVRILDQMPALRKLELWNVQFRDCHGHGMVVPDKYQGITSVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIE0</accession>
    <name>A0A1D2NIE0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN04999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIE0"/>
    <dbReference type="STRING" id="48709.A0A1D2NIE0"/>
    <dbReference type="OMA" id="CGQIEYL"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03428">
        <property type="entry name" value="NUDIX_Ap4A_Nudt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003565">
        <property type="entry name" value="Tetra_PHTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01405">
        <property type="entry name" value="TETRPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="16479" checksum="21505D5FBB680621" modified="2016-11-30" version="1">MTSPVRAAGLIIFRALGQLQFEYLLLQTSYGEHHWTPPKGHLDPGEDALTAAKRETEEEAGLPPSSYEIQQGDEFPLTLEYPVKGKPKKVEYWVAKLINPDHPIKLSDEHINLAWVDLNKSKEMTHDNFHGLMTKVEEYLQANAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIY0</accession>
    <name>A0A1D2NIY0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neural cell adhesion molecule L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000028">
        <property type="protein sequence ID" value="ODN05220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIY0"/>
    <dbReference type="STRING" id="48709.A0A1D2NIY0"/>
    <dbReference type="OMA" id="CFHHISA"/>
    <dbReference type="OrthoDB" id="6377396at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF6">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 7, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="68"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="19888" checksum="100BEEAD31A3166A" modified="2016-11-30" version="1">MHCWFSCVKVSWIRKRDLHVLTSTVFTFSSDARFSVIHPENSDDWTLEIKFVQKRDAGVYECQVNTEPKMNLAMLLNVEEAQAKIAGPEEVYVKTGSMISLICSVNIHSQPAGSVTWYHGSNIVDFNSPRLETEKTEAGTTSKLVITRANTSDSGNYTCLPSNAYQASVWVHVLNEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK75</accession>
    <name>A0A1D2NK75_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcium-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK75"/>
    <dbReference type="STRING" id="48709.A0A1D2NK75"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="74" mass="7840" checksum="78590ADD4EF20700" modified="2016-11-30" version="1">MAAPHVAGAAALLLSRNPNLTYTEVKELLENNADRDLQDTGTTCGGIPSTEFPNNQYGNGRVNVRKALEAAINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKU3</accession>
    <name>A0A1D2NKU3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeotic protein antennapedia</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000014">
        <property type="protein sequence ID" value="ODN05861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKU3"/>
    <dbReference type="STRING" id="48709.A0A1D2NKU3"/>
    <dbReference type="OMA" id="NRMDMRN"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001827">
        <property type="entry name" value="Homeobox_Antennapedia_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00032">
        <property type="entry name" value="ANTENNAPEDIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="132"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="308" mass="33576" checksum="0A1EB35F0A2668AE" modified="2016-11-30" version="1" fragment="single">MTSYFTNSYIPDLRNGTPDHYQTCTTPVNGATPDPSCDPRNSIHHYGNHHNGQGGQPLYPRFPPYDRMAVGPGGPGTPVQYYQQQGGGAGQLMENQYRPPSPPPSVNPGIPMGGHVVNLGQTPGGYSSCKMQQQQQQQQQQVPQVPQHQSPGANGPPLGVVPPVVNHNHNQHPGVVGGPPLSPDPVTGQSNHVNVVNVNHMNNPQNGNHHGSHNHMGMYNNMGGAPPQPPQHPMNQMHGQPPQQQPPPQLPQQQMGHHPNQNHQNPHQSPQQQNSPASVLPSPLYPWMRSQFEIRDTAYDNVNVPIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLD9</accession>
    <name>A0A1D2NLD9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">[Acyl-carrier-protein] malonyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_00957</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the type II malonyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLD9"/>
    <dbReference type="STRING" id="48709.A0A1D2NLD9"/>
    <dbReference type="OMA" id="LNKTQFT"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.250:FF:000005">
        <property type="entry name" value="Malonyl-CoA-acyl carrier protein transacylase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052760">
        <property type="entry name" value="Mitochondrial_malonyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170">
        <property type="entry name" value="MALONYL-COA ACP TRANSACYLASE, ACP-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170:SF2">
        <property type="entry name" value="MALONYL-COA:ACP TRANSACYLASE (MAT) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="13">
        <location>
            <begin position="72"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00077751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN05766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="30626" checksum="A29BF1628EE90F92" modified="2016-11-30" version="1">MRGVRLRNLRKLIQDSSTFGAPLEDGKIGGDPFLTGPFAKGTKLSVYFDQGDNAAEESMRRKINPSDTSVIMFPGQGTQHVGMCGDTASMPRHVQVLYEIASSILNYDLLDLCANGPIDKLNKTVYSQPAILVSSLAALERLRDTEPGVIERCVVTAGFSIGEITALVFAGVLSFEDAIRVVKVRAEAMQLASEIVPSGMSTVLYGADSKLNYSLVVAKEWCKREFKIDDPVCSIANYLFPHCKVVAGHTEALDFLEANYKDFNLRRVKRLPVSGAFHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLY1</accession>
    <name>A0A1D2NLY1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_00417</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000008">
        <property type="protein sequence ID" value="ODN06262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLY1"/>
    <dbReference type="STRING" id="48709.A0A1D2NLY1"/>
    <dbReference type="OMA" id="NEGTHFQ"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="40"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN06262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="305" mass="34240" checksum="CFCD8D14A82B1C93" modified="2016-11-30" version="1">MAQSKLNDWAGRLGKNPRGLGIGLKLVAAAAAAVYGVNQSMYTVEGGQRAIIFSRVGGIQNDIYTEGLHFRIPWFQYPIIYDIRSRPRKISSPTGSKDLQMVNISLRVLSRPDAYSLPIIYRQLGLDYDEKVLPSIVNEVLKSVVAKFNASQLITQRQQVSLLIRRELTERAKDFNIILDDVSITELSFGKEYTAAVEAKQVAQQEAQRAAFVVDRAIQEKQQKIAKSLTTSVGPTVKIGENLRIMVLHCYLKLRKIRAAQGIARTLSQSQNKLYLNGNSLMLNLSDKEFDEPLEKLDKKKKAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM18</accession>
    <name>A0A1D2NM18_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Rhomboid-like protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00403</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000008">
        <property type="protein sequence ID" value="ODN06291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM18"/>
    <dbReference type="OrthoDB" id="10257275at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="10">
        <location>
            <begin position="132"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="448" mass="51099" checksum="252939452716D712" modified="2016-11-30" version="1">MTVNQNEASSQCLDQNGNPASTVTSSASTFANHNRPTLNPVLLETSHRSSRSNTNFHYHFRDASTVITEQPPSNENVRRRRYLMESRAALYLPPVATSICALLISLYFFREYVHVFGEADIYVSWNKIFKEKQIWRLFVAQFFHFSRVSVVISMFTLYAIGRYLERKVTTVAMLSVIMVMSVLSHVLYIFLNPYFCVGEQTEFVWGFGNVVYSLRVMLAYALEPRNHERDLVFGLYPMVLSANAAPWQPVLHCHIYLASVATEGIYIANPPYFWVPDPEPENPNNDERNGGRWRKWSSTSWKMETYPSRDFFVSPPSDTALDSQTLEAEPTRVNNELIRTNANALKRNSDELKRKISKFLVTAKESLVRKLGKGANKDGKERSENCKLLHKRRRKKSRKSIVIKLQPPPCSTISERSSGSVSSFDPDCLTGDLTFASDMLIEPASAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0J2</accession>
    <name>A0A1D2M0J2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_20203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008835">
        <property type="protein sequence ID" value="ODM66919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0J2"/>
    <dbReference type="OMA" id="TIQHECH"/>
    <dbReference type="OrthoDB" id="421276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049012">
        <property type="entry name" value="Mutator_transp_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051703">
        <property type="entry name" value="NF-kappa-B_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46609">
        <property type="entry name" value="EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46609:SF8">
        <property type="entry name" value="YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20700">
        <property type="entry name" value="Mutator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mutator-like transposase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="YqaJ viral recombinase" evidence="1">
        <location>
            <begin position="384"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM66919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="481" mass="55376" checksum="0140AB8C390177BF" modified="2016-11-30" version="1" fragment="single">RSYGHSYNSKYGNAAILGVRTGKVLFVGERMTTCKMCQSNERYNRTIQHECHKNWSGPSTAMEADLIYEGFSKSFETHGLVYQFFVADGDSSTYARIKDVYQEFTVQKIECINHVIRNLNTKLRNIAGNSVKRRCISKEERSLPRMESRFKRVGLAVQSACRYYKDLGNWETNWKNLREDIKNIPFHIFGRHNSCKSYFQCSLKDKEPDISRQSHCFGTRDALDRVASLANSLIRRENSNIVECFFSVCAKYLEGKRKNLGAGFLYHERIAAATLSFNNSKFWVGDLFKMNYLKSPCARWKQEKMRSTRFRNKISKKKPRMLSFPFLKAGRGDENYGTDPDRPDLNEEMLKEEMDSIRRAVTVDKERQQEIQISTLGQSNCEIWGRERRKRLTASNAKRICSMQDSTDNHAVLRQLLSLTEFSNEATIYGNTNEAVAADKYAEIKSLSKDEVKMCGLFVSLEHGGLAVSPDRLVEMMASSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0P4</accession>
    <name>A0A1D2M0P4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008361">
        <property type="protein sequence ID" value="ODM86537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0P4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="13012" checksum="523BC731EF8E4511" modified="2016-11-30" version="1">MLKALRKSVVRRYYRTRNSIRNGNMAHFNKQSRWSICHNCRIASLANPKLPNLRIHEISVKKNMLWRDSRKNGFWLPAIPLQLSKIFAQIARSNLRFTLEKLIDSLQPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M295</accession>
    <name>A0A1D2M295_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Choline oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006245">
        <property type="protein sequence ID" value="ODM87064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M295"/>
    <dbReference type="STRING" id="48709.A0A1D2M295"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF227">
        <property type="entry name" value="GLUCOSE DEHYDROGENASE [FAD, QUINONE]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="235"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="399" mass="44908" checksum="06ECA77044854CD9" modified="2016-11-30" version="1">MNCNLVADDILSKRVAFSIRGISGDARFYKVNGARTVKSLNVGKQSLDFDSLKDQYEYLEGLPVSSYVDGRPRILLGQQEKLLSLARKYSGHSVLPKMMNLVMAEDSIFDENHEVQEIELSIKNRDTCVPAASMQEKHEECLKDLGPSLPMQAARCCVDSFWTRWFRKCSPFNDGESWVLESWKSDLQFWLEWTLGRIEKPSSNIGGECCGIYYSDPRGQDMNVMLEGIQTVSKIKELLECVTRTLTGTLYHPSSTCSMGKPGDPGTVVDSQLRVAGTRGLRVADSSIMPKLVNKMEGFRLPPRLIAKLLVPTAILMLLASHYGMSQWLSHGHSLYTTAYSKNCRQTHKLVDIVSEAELGRIPEAQTPEILKFCFKLRKKRHFLFKGCSGSSTGYMDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2D4</accession>
    <name>A0A1D2M2D4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006096">
        <property type="protein sequence ID" value="ODM87128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2D4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="16431" checksum="F74A9490CC10997E" modified="2016-11-30" version="1">MPSKSHEANSSRFMEDSNWSELQPVEGDYSTFSRKEFDNFKKKADDLFTKNFRADLLNPEDPPHLYEWRRNNNNKALFDMLLAWDRLDEVFEELRCYHFMSYEQLRPVTLKMAKEDLKNCFSTGVQFAWAAVCECHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2U6</accession>
    <name>A0A1D2M2U6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01005634">
        <property type="protein sequence ID" value="ODM87298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2U6"/>
    <dbReference type="STRING" id="48709.A0A1D2M2U6"/>
    <dbReference type="OMA" id="MFERPIR"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="25414" checksum="434104DBB77DFA34" modified="2016-11-30" version="1" fragment="single">VPWSGSYGEVYLGQSISTPTEQVALKVENMLGKRWLLFYERTFYQSLERGAGDRGRVPRLKDYIQDFDYKVNILVLELLGHSLDHWFNYCSNKFSLKTVLQIWDQMLENLRFIHEYSITHGDIKPANILMGLGDNSNMVYLIDFGLATQYRDTKTCRHMKDGIGGGRWHGNSMFGSINDHRGVGRSRRDDLEALCYMLIYSSAVPSLGAMFERPIRDKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M305</accession>
    <name>A0A1D2M305_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger MYM-type protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005566">
        <property type="protein sequence ID" value="ODM87322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M305"/>
    <dbReference type="OMA" id="FESTHCI"/>
    <dbReference type="OrthoDB" id="6619433at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025398">
        <property type="entry name" value="DUF4371"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45749">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45749:SF21">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14291">
        <property type="entry name" value="DUF4371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4371" evidence="1">
        <location>
            <begin position="4"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="287" mass="32491" checksum="02957F01B10D8604" modified="2016-11-30" version="1">MRYFSIIMDSTTDITKKEQVSVILRYCTFDETGPTLVTNESFIGFFEIVDRSAKGYEALILDVLKGLNLSFAMCRGQGYDGASVMSGAHKGLQANLLKLNQHALYVHCAAHKLNLVITDGVKSRTSMSDFFDTIQSKILRSFSVLSKKLQSIEITLDECVIMWQNGIETLESLKRNICGINEEAKELARKWGVPEGFPSVRKIKKSRFHDGLGIDTARKTALTEEGLFEKEFLPVIENVICQMKTRFESTHCIYELFGFLTPSKILNLNETELSEMVVRFCQKIVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3Q0</accession>
    <name>A0A1D2M3Q0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004984">
        <property type="protein sequence ID" value="ODM87603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3Q0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903434" evidence="2">
        <location>
            <begin position="19"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="42263" checksum="E9240452B68FCAB1" modified="2016-11-30" version="1">MLPLLLFVLLIVLEQTQGQPVDSADDKSPTKRWKTIGTQDFLSRWMAQDSKTATTLASSQSGIRSGGKQTNTQPTTTATTPFPYRETTSSTLRNDESSTALELQRHFSQCTTNSNGWLNNVATEATTPVVESNIVADIQEAFKHPQTFLSTVIKTATQVFSENQDTLQESRSIDVNVETTKQPATTIRTYQEEPNKLTATTTPFTVDLTAKIFEKLQTSVESILPLFKQGGKNEQTTTKRPGNSQGFDMEGILKMFNIDGSKASLIIEFFSKNNLNVLEVLRDSNVSLGEVLDIFQTGDFSSKKTQDILMKIAMQIMMKKSTKESETTEPSFDASALIKTFMEMTMTTTTPAPAGCNNRNVINQNVIMLPILIFTLFYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3X1</accession>
    <name>A0A1D2M3X1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004891">
        <property type="protein sequence ID" value="ODM87659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3X1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="257" mass="28895" checksum="8A1A970833E68F3C" modified="2016-11-30" version="1">MSLIAPRVKLLRFHERGVEMWWNNEYLQNIFCFNCTHPHGTRSARRHQPVNISDRNCPALGCTGNLTSDTFNGKGSIAATILPTASSTSSKDERFDSPEFLQHHHPLKIEIKSITNSTIANSLDSSYVHVDEETGRSDDEFPVSAFFSWAVYWLFKIKSSIADDYIEYYVKLGQDSKHPFSSYGGGWLLFRVLFSIRLGDDGAEIPVSQTFHLCCEVEDAVGSIVAAIEPFPLNVSDVRFPVHPKAGQFLSEMLTGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4F5</accession>
    <name>A0A1D2M4F5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004553">
        <property type="protein sequence ID" value="ODM87849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4F5"/>
    <dbReference type="STRING" id="48709.A0A1D2M4F5"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="21"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="199" mass="23086" checksum="0EB1F6D2964C6134" modified="2016-11-30" version="1">MQERDGIAEIRSLLNAFPTEPIDVIGQLKKYGVVGMLKARDKLGRRILFLNAEKWDPDEISSEQMTIMGLYLLERGLRDDDMMTNGIVFIHSCSGMGLKHAKLYTLHKTLRIINICWYSYPLKVKGIYYVNVPIYLVYLYKLVKPFLTSKFKERLKLSTKDNTFETLHENLSPDLLPKCVGGILEDEEAFDWEFLETKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4P2</accession>
    <name>A0A1D2M4P2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01004337">
        <property type="protein sequence ID" value="ODM87950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4P2"/>
    <dbReference type="STRING" id="48709.A0A1D2M4P2"/>
    <dbReference type="OMA" id="TENEWFT"/>
    <dbReference type="OrthoDB" id="1740265at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000001">
        <property type="entry name" value="Maltase A3, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF179">
        <property type="entry name" value="NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="6">
        <location>
            <begin position="66"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM87950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="618" mass="71223" checksum="0CD2001D2C26A1B4" modified="2016-11-30" version="1">MDLHLHLPAKSSTVSILTSFTNKSAMIVYYCVIFFDLFSSRGISIKLPENPNPQPLKWWQSEIIYQVYPRSFMDSDGDGVGDLKGIESKVDYIADLGAGAVWLSPIYESPMKDFGYDISNFTNIDPIFGTMDDFLSLATKLRENGLKLVMDFVPNHSSDLHVWFNLSVHRQEKYEDFYVWKNASGYDSEENPIVPNNWVSFFGGSAWEWNEIREQFYFHQFVAGQPDLNFENPEVLHEMLEIMKFWLDMGVDGFRMDTVPSMFEDQRFLDEAEDPNRPPNSIPTDYSYWSHIYTYDLPATRDSWQISENYLISDGKERCMMIEAYVGSLDKLFLYYGTKTKPIAHFPFNFEFITRSNQVDPFNMLILLLPGSAVTYYGEEIGMTNTNLTWEETVDPPGCQAGPERYQLFSRDPERTPMQWNYDKNSGFSTGDSTWLPINPNYKELNVQAQNETSGDSHLKVYKQILSLRKTDTWKYGSLEAYALENGQGFGFARIYKGSGFIVLANYLDGDMIINVGEHFKDIPDSAMVYTTSVNFQPEMSVGSFISTKSVTIRGKHSIILTFSKSENEKKNDTWIWTIVNWILLSKANFYLFTIISDLNNGHIVKPVWNLQNNYNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4S1</accession>
    <name>A0A1D2M4S1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative G-protein coupled receptor Mth-like 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004317">
        <property type="protein sequence ID" value="ODM87963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4S1"/>
    <dbReference type="OrthoDB" id="7683403at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051384">
        <property type="entry name" value="Mth_GPCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47154">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47154:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26281" checksum="838F705F9CF05934" modified="2016-11-30" version="1">MFDAMYRDFATSPVILPAYGKSVCSMSNSDGITFYLYIPISVLLLFNIGFFLATIMTMMQYKKGIRDAFNGISNNTSTKVDQSFGIYARLFIIMGIFWITQIVCWFALPQSDNSKTFLSLCISGGCCTTPPDISRKISMPSHAMSLTRKGTRHTSQDMSTETAKHRISTESNKTIVLNVRNPVPSITSEDSRKISVTSNETVISHVESGFKVPGVMDDNKLNGLSRTVSSEPAAETSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M550</accession>
    <name>A0A1D2M550_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Izumo sperm-egg fusion protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004216">
        <property type="protein sequence ID" value="ODM88031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M550"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903480" evidence="2">
        <location>
            <begin position="28"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11849" checksum="7D8B3D03636A8C60" modified="2016-11-30" version="1">MNAKNMLKFSRTLFGALLMTSAVLVDGFPSKCHLEDESKKCETRELSLGLILLCTFVVSLVLLVLFCCCFARRSKAKVPLESQLDHNNYNPASDQLFNINNIRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M644</accession>
    <name>A0A1D2M644_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_18298</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003660">
        <property type="protein sequence ID" value="ODM88384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M644"/>
    <dbReference type="STRING" id="48709.A0A1D2M644"/>
    <dbReference type="OMA" id="NIHECEI"/>
    <dbReference type="OrthoDB" id="5803930at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF23">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="214"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="242"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="270"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM88384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="342" mass="39421" checksum="54291B44317C7486" modified="2016-11-30" version="1">MHEDKFADEDEVDRFTESDGEEPLVKVELLDNNKFENLEEVDDQDPFSDCNLQAERQTKKGRARKFGCSVCSKSFDSEERLKTHYKNFHTTIPCKSCDKTFTNLKFLKGHEERVHNPKGSFPCPICFKVFASRLKVWRHKRSTHENKTYRCSDREASFKTQSGLAYHVNAVHKPAPVPCPHCQTVFSHRSNLKRHLRLKHSNQGKGNPVPIEPVPCPTCGKTFSNWEGVSTHIRDVHGNERFSCSECNVVVKSKKQLNVHMKAVHNPEMHICQICGKSFSTAKYVKQHLTRYHPTPAQKESWVKCPRCTKPFHQNYLLKCHLLRSSCRLGKSEETQAVAEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M700</accession>
    <name>A0A1D2M700_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003249">
        <property type="protein sequence ID" value="ODM88748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M700"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="879"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="504"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1173" mass="130497" checksum="0C02EAA66C99AE5D" modified="2016-11-30" version="1" fragment="single">CKASSLTLLLKTSKTVAICPLNEEVEDGGEEYVQPLEIQAQGEQLDAFVEDEQTVALYSPDKEVVQPMEIQTQGEQLDTFAECEQTMRKKERGAEKKNDREQPEEMNIVLVSPSVAEQTESIDNTLLLNSNPEVVKLDESSERLSPSSLAAPSVEWQIVHEDAQVEADNEEERNTLENEMEEVGSTVSAKVHEQTENVEGMILPDQHIDAEQEREPIPGTEEEENVEVAALLAYISVLKNRIVKLSESRRAGIPEEEQPLGAEPASVRSSEEKDEEEALSIGQEMDCDPVVSSTEEGIVKNIVTLGSHHESVPIPDIPEETKETGEVESMVEEFDHDSCSVFDSVEVPSSVVTVGEEEKLGNETEEQTPGAVEETITQAPAPPVEEIEEAPNSTSDAISLCDNDDDERLDLCDEVYEPTEQPLREEFEESSPDIEASDSEDGKLFENETDLDTDTEVDEQEPPAAASNTEHLETFQVEANGASSVSSPVPVQVNENVGEQLAIENEDESLESVEEMQFEQQEEDDGMETEDESAPQEGNGMLTALCNVASFLIGLADVAEKVEQQQVPRDEIDRDSAIQVAVEETIDAVVEKVVETETVDFETNSWVQIETEVVSGEGAELEDMVLCVSPNRDYPLVESDSEVEGEGKAEEAAFDDDEEDDNETACSSESEKAPPYSPLSPYPKPGGRQNYEDEGHCSISPQEPHVFQASAEADNEEGAMMATELPFPEENYEIVSPPTPQLTIEIGQEEDDLSFESGLNEEQDLVMISRPAVPEENIEQAAEIVDAEVEDLSAFFWDTFTLKDSTGTQPEENTVYETGFRVAGAAPSNEGVGGKIRYAVFTSKSNQVDDEKDVSGDDQPSQEVVVPNTLYCVTNIRNNNDLRKALECLKMQRQQEKEQEEEVDDDDDDYGRLYIDEGPWTEQQDDIGFNDNPPVPINLGRVDLVDDFDGVVVQIREEGFCPYSSLPYSASYHHHHHPSEIDGGTEAQRSYLNLEHLQDDIEYPPQEQALDLSSKSQQREMEVGIKFCARLGSRAALEREAFPNSVPLRLSLPSSEDNLEIRGDPLMTPSTPEPPPSGIDLILQASKEVELRIRAESRHKRYLARRLAHLRREESKRIRKQLEAGVADPTGIIGENTRQLLRAKWAMRPVRNFIVFSATINNYYERVLMKELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M711</accession>
    <name>A0A1D2M711_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Long-chain-fatty-acid--CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_17923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:54537"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>tetracosanoate + ATP + CoA = tetracosanoyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33639"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:31014"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:65052"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:33640"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003230">
        <property type="protein sequence ID" value="ODM88759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M711"/>
    <dbReference type="STRING" id="48709.A0A1D2M711"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="50"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM88759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="549" mass="61878" checksum="3E229D5DC9333809" modified="2016-11-30" version="1" fragment="single">LLYVLYYKILFQWIKRKRRNETIAKSLDNIVGEGEGDRVCFYFGEEMDLQIQALSFRVANHFQRIGLQKGDSVGLAMTNRPEIVAIWLGLGRLGVVTALINTNLRGDSLEKCVSVVKCKAFIIGKEQKSEDPTWKPKTQNFTDLFPTIDLAACLLKAGSQPTSLAKDQQPNYLDPLVYVFTSGTTGVPKAVACSHGRLCFLASTASVVNLTPKDVVYSALPMYHVGGFFAPVWAFVFRSPIVLVAKFSGNNFWKHVHKYKVTVSGYIGEYCRFLYNQPHSELEKGHKLRAFFGGGVNLEGKVGACGYIPIWFQPIHPIQLVKVDQRTGEIVRDEKTGFAIQCKDGEPGELIGKIVDSVPMTRFDGYTDKEASERKIARDVFKQGDKYFRSGDCLCRDKYGYYYFTDRMGDSFRWNGENVATTMVEAVISKALGMRDNTVYGVKIPGIEGSACMAAILDTVGEFDVQSLAERMKQSLPKYAMPMFIRLINNNKGLDMTGHSNSKKFRLRDDGFNVEYIEDTVFIYSTAKESYSKMNIEKCKEVMRGNYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7K5</accession>
    <name>A0A1D2M7K5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxygen-dependent choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003067">
        <property type="protein sequence ID" value="ODM88911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7K5"/>
    <dbReference type="STRING" id="48709.A0A1D2M7K5"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="19574" checksum="D4DFC923ED7771ED" modified="2016-11-30" version="1">MSCSAQLLMLYGIGPSEHLKSVGIMPLVDFSVWRNLEDHVMTFAGPFILKKNGSVPVSSMSSDVTLGALNDFTINGVGPFTSAMGVVATGVISSSSSPGWPNLLYFILSTGVPDGLGAAIDGIFGSGNYTAELLHPFIGQDAHSSWFQLESQKGFIELLDKNLFPSQSSTPNTILIAEIKTFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7X4</accession>
    <name>A0A1D2M7X4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002965">
        <property type="protein sequence ID" value="ODM89031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7X4"/>
    <dbReference type="STRING" id="48709.A0A1D2M7X4"/>
    <dbReference type="OMA" id="WKANTKS"/>
    <dbReference type="OrthoDB" id="8053926at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33332">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="496" mass="56994" checksum="586C79044148037E" modified="2016-11-30" version="1">MQTTKRPKNTKTIVYRNYKAINQQRLSEHINKCGIVYDSNRTIEENTQLLVDSIKNTFQENAPTKIKTVVISNRVEYVSPETKSNDVQQRILATTKRLKPLSHNVRQYEKLKREVKKAIKADMKKFLRDKINKDGLWSVVNSLTTTTDQKEIRFEADDINNFFINIAPKPTTIPNSNSKTNIDNDNLVVPKFKLVPLHPSDIQRAWNKMRNKNRTAIATIDIFKAFDTVPREILKNALIKCGIDDECIFSYINGRQQFVLNNKQKSQVKYTHAGLAQDDTQLLKSINPNDQDSDIQKLEEDCNNVDVWMKNNGMKINATKTELILIPVSRKQEGRLISIKIGGTTVTSQNQIKSLGLIKDQKLNWKANTKSVKSKCNKALWKVRSLSALLDPKSVSLITEAIVLPTLYYMITVWATVNNSTCDKSINYSTVLRRMIHQETDNCDKIWLPPKAQYKYEISMLAFHSLHTSGPDVFNNKINLNVIQTRETRRKCHPQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M827</accession>
    <name>A0A1D2M827_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras-like GTP-binding protein Rho1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17617</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002941">
        <property type="protein sequence ID" value="ODM89064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M827"/>
    <dbReference type="STRING" id="48709.A0A1D2M827"/>
    <dbReference type="OMA" id="RMKQDAC"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002060">
        <property type="entry name" value="Rho family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="19613" checksum="A229AFEB5BDEE16A" modified="2016-11-30" version="1">MVANQFPETYVPTEFDISTAQMKLDGNQVELTIRDTSGQEDYDRLRPLSYPNSNAVLVCFAVDAPDSLENVAEKWSPEIQYYCRGIPVILVGNKMDLRDDPNTIHKLSKKQQEPVTFADGVWVAQKIGAQAYLECSAKSGERVQNVFETAAKVALQLQSPKPLAPSKKKCGGCCRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9J8</accession>
    <name>A0A1D2M9J8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002498">
        <property type="protein sequence ID" value="ODM89611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9J8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903666" evidence="1">
        <location>
            <begin position="20"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="305" mass="35165" checksum="85EC3B9177BCC5D3" modified="2016-11-30" version="1">MRYSIFIVFLACFAANSQASSKSNPRKITDLKSLSPFEKLGLLAISSALPEKNLNISRNSLFAEEEHELIDLYYHDLRTLLTQFVKIKEDAPFPEITDYSWFELCLPFCASWGITLETNRTSITGQERTTSVNEITPTSFKNTFHVPSFVWTSPDFLFEVNDETALTRWIWRNMRVALNNLKWTTTFDYDVDPDLGLQISNLDIKFSIYWLRINIYIVGTINSGGWFIPVPPIFTDWTTNLRAYWANYKPQYLSLLTHRINCVLSNSRSDPVGCINGTATLSEKYHKMNVVQLFETFGLGELDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9P5</accession>
    <name>A0A1D2M9P5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002495">
        <property type="protein sequence ID" value="ODM89614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9P5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="202" mass="21918" checksum="985F54575ABC8017" modified="2016-11-30" version="1">MSCGRPSPCCPPSCCPPPCCPPACCPPIVIKTRNQQQQGQCCVFQLPPVNIVCEIPPPPKNKNPPKVCCIPLVMCEDDDGGNGGGGCCPKPQPCCPSPCGPPCCIPIDFGCPQRGGAGGCGQRNRREKRWPQCNFLKPCIDARIYRNGEHLCISYAGHIPGEQYIHGRNLPTTTTFAKRRLCQYTPYEFVDPDGCCSFCVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9R1</accession>
    <name>A0A1D2M9R1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002448">
        <property type="protein sequence ID" value="ODM89679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9R1"/>
    <dbReference type="OMA" id="KRECKPF"/>
    <dbReference type="OrthoDB" id="10473849at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="16659" checksum="5F44A51BC27E1D26" modified="2016-11-30" version="1">MEDKLKRECKPFLEKLFKKQDELKSGAVSMVGMRKILREMIPEFNQEEELAEMMGELAKKTKYTMVNKQTNKMEVQYQENSIDFPSALYICVYFLKKLERRNTDCFSGKSVVKFDDLTGVTLNPLENRQRGKDPGERRRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAI1</accession>
    <name>A0A1D2MAI1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002282">
        <property type="protein sequence ID" value="ODM89941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAI1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="19606" checksum="953ACD7C4A81E95D" modified="2016-11-30" version="1">MAFNPCPCVPIEGSVKGFAFFDGHFKKQVVGILRIIWGTTLLVFVSLEPADHPHLHHLKVAAIVILSFFLVFTLSEIGLAVLLFSGVKNRSSSKCSLWLVVTGIIVGFSILTAISRQLVNGDTELVLLGMVIWILFKIYESLVVYAFIQGVNGGNKGSGVVYPNSDTRLLEPSNPQPPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB01</accession>
    <name>A0A1D2MB01_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002126">
        <property type="protein sequence ID" value="ODM90178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB01"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18779" checksum="340EAC30C6AABB17" modified="2016-11-30" version="1">MNFLFLVYFHSCKNASESLPMYDFDDWCDDSGDNRAVMSIFFILAISAFLIALDYPTIYFDCKKTPRVYEAAKHGSKGTFVIALIINVVDLLVSVLGWYCGAKMKLIWYCIIWFGFLSMKAILDTADLILVLKGYTSLTKRRVPMFSDSLILSFKSTQLLLSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCF0</accession>
    <name>A0A1D2MCF0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Actin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_16007</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001855">
        <property type="protein sequence ID" value="ODM90676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCF0"/>
    <dbReference type="STRING" id="48709.A0A1D2MCF0"/>
    <dbReference type="OMA" id="RNLMSFR"/>
    <dbReference type="OrthoDB" id="422673at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.36.70:FF:000001">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.36.70">
        <property type="entry name" value="Actin, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0558">Oxidation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM90676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="37588" checksum="A43A54230BB05559" modified="2016-11-30" version="1">MCDDEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVSIQAVLSLYASGRTTGIVLDTGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYTFTTTAEREIVRDIKEKLCYVALDFDQEMQTATFFLPLRNLMSFRRPSDHHRNERFRCPEALFQPSFLGMENAGIHETTYNSIMKCDLDIRKDLYANTVLSGGHFPCYPWHWLIGMAEAELDYHPPWLQPHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD56</accession>
    <name>A0A1D2MD56_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">G patch domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001734">
        <property type="protein sequence ID" value="ODM90946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD56"/>
    <dbReference type="OrthoDB" id="20507at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10414" checksum="381FB71AA0013CAE" modified="2016-11-30" version="1">METRKGTCAGKDPKDDPKVAAKMKLFGRLTHNVMEWHPEKLVCKRSKFVGVKNDQSASSTTIAQAVLAVPVAKKSLFDNLDFSKRHLVFFLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDG8</accession>
    <name>A0A1D2MDG8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc metalloproteinase nas-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15625</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001688">
        <property type="protein sequence ID" value="ODM91058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDG8"/>
    <dbReference type="STRING" id="48709.A0A1D2MDG8"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903851" evidence="7">
        <location>
            <begin position="22"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="8">
        <location>
            <begin position="76"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="8">
        <location>
            <begin position="127"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="194" mass="21628" checksum="68E8CB24E32A0A0E" modified="2016-11-30" version="1">MKRLFLICIIFQLSLIWEAACFPTENSIPAEPQLDSNAVCDNDRLLISNAAYWLGRVLPCVAFGVWGKGPPPTDYQDTYIHIKETGNGCSSHVGKSQIPGPQEMSLDPVCMTSETIMHQMIHALDARSKFDRLSSDEAKTFGIPYNTRSLMHASSYDHSRNGQPTILTKAGGIIANIGELQWTDIQKLMMMYQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDQ4</accession>
    <name>A0A1D2MDQ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Putative neural-cadherin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_15534</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Cadherins are calcium-dependent cell adhesion proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cell membrane</location>
            <topology evidence="1 15">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001650">
        <property type="protein sequence ID" value="ODM91148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MDQ4"/>
    <dbReference type="OMA" id="EPWCAKV"/>
    <dbReference type="OrthoDB" id="6079678at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048589">
        <property type="term" value="P:developmental growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001736">
        <property type="term" value="P:establishment of planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000182">
        <property type="entry name" value="Blast:Putative neural-cadherin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.900.10:FF:000001">
        <property type="entry name" value="Cadherin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000039">
        <property type="entry name" value="FAT atypical cadherin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000040">
        <property type="entry name" value="neural-cadherin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000044">
        <property type="entry name" value="neural-cadherin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000128">
        <property type="entry name" value="neural-cadherin isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.900.10">
        <property type="entry name" value="TCF3-CBD (Catenin binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000233">
        <property type="entry name" value="Cadherin_Y-type_LIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027397">
        <property type="entry name" value="Catenin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056370">
        <property type="entry name" value="Shg-like_Ig-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF438">
        <property type="entry name" value="CADHERIN 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01049">
        <property type="entry name" value="CADH_Y-type_LIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24811">
        <property type="entry name" value="Ig_Shg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 13 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 15" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 14" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 15 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1272"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="20">
        <location>
            <begin position="8"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="20">
        <location>
            <begin position="150"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="20">
        <location>
            <begin position="212"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="20">
        <location>
            <begin position="310"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="20">
        <location>
            <begin position="414"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="19">
        <location>
            <begin position="778"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="18">
        <location>
            <begin position="815"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="18">
        <location>
            <begin position="1008"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="19">
        <location>
            <begin position="1242"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="804"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM91148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1475" mass="165903" checksum="51C4D4697C4B4A8D" modified="2016-11-30" version="1">MLGPPVFDQGTYVTQITEEEDVNLPKNILKVTATDGDRDRPQNIVYFLTGQGIDPDNPANSKFDINRTTGEIYVLKPLDRDQPNGRAQWRFTVFAQDEGGEGLVGYSDVQVNLKDINDNAPMFPQGVYYGNVTENGTSETGVIKTAVCCLDREKTPDYSIQVVAIDGGGLKGTGTASIRVKDINDMPPHFTKDEWYTEVDETQGLTIPDAPILTVTVHDEDETNKFHYKVLENSGYGADKFTMVRNNDGTGSLKIVQPLDFEDPLQSQGFRFRIQVNDKGDDNDNDKYHVAYAWVKVGLRDINDNSPVFEKPNIEVSVYENAEVGKSLETFKATDPDQGGKSKVSFHIDRSSDRKRQFFIHQDGTVTIQRALDREDTPRHQVKILAVDDGVPPKTATATLTVIVQDINDNAPQFLKDYRPVLPEHQPPRKVVEVLATDDDDRSKGNGPPFTFRMDPNAADEIKASFKVEHDPKGANGDGMAIVSSLRLFDREQRKEFLVPIVIKDSGNPAMSGTSTLTVIIGDLNDNKMQPGSKEIFVYNYMGMNPDTEIGRVYVYDMDDWDLPDKKFYWKNRDAPHPRFYLDEDTGMITMKQETRPGNIAANVTVLVKDLPHDAVINHGSIRIAGISDEDFIRIWDYKTQSVVKSKYLKFKAKLAQILNTEESKIDIFSVMQKQARPPITDIRFSAHGSPYYKPVRLNGMVLLHREEIEKEVGINITMVGIDECLYENKNCEGSCTNSVDISPLPYTVNANKTSLVGVRIETIAECMCGARNFSEKDKDSCRKYECFNGGRCIEAKSGPMCKCPHGTDGPRCQITSRTFKNHDWAWYPSLEMCEESHLSLEFITKKEDGLLLYNGPMTEPELDEIVVQDFISLELDKGEPRLLLDFGSGTLELKIKTNGSLANGEWHRLDVFWDTEDVKMVVDLCKWARVNEADDGSPNVFDSSYCQAEGKIPPFNEYLNVNTPLQVGGIYVDHLDTNHYRWKYIPTQKSFDECFSGWMGPGCTIPTVPTTFKSQSYVKYALSFEPDRFTTLIQLRFRTREAHGELFRISDQHNREYGILEIKDSRLRFRFNLNSLKTEESTLWLSYVSVDDGQWHVVKVSRHGSVAMLELDGGEGRKYNETFKFHGHQWMLVDKQEGVYAGGKAEYTGHRSFEVYADYQKGCLDDIRLEGKHLPLPPALNGTQWGQATMSRNLGQGCPSNQPCTNVICPPPFECVDLWNEYECACGEGTEMSADEKNCVDKNECLDNPCLNGAVCSNREIPYRFYCEGQILTLSMGALAAILVCLLIILILVLVFVVYNRRREAQIKYPGPDDDVRENIINYDDEGGGEDDMTAFDITPLQIPIGAPGHEMMMPKMPYMMKMPDPQAMPPGEPNVGIFIDDHKRRADHDPNAPPFDDLRNYAYEGGGSTAGSLSSLASANLADIDAYTAATSAILHESTDDGEQDFDYLNSWGPRFQKLADMYGQGESDEDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDW4</accession>
    <name>A0A1D2MDW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001668">
        <property type="protein sequence ID" value="ODM91112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDW4"/>
    <dbReference type="STRING" id="48709.A0A1D2MDW4"/>
    <dbReference type="OMA" id="QKVICTA"/>
    <dbReference type="OrthoDB" id="6623841at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="340" mass="38517" checksum="82645777E38FB841" modified="2016-11-30" version="1">MPKQGRDFGTKVRGWLLQLQETERKYFVVEGQKVICTACCKGFQFKMPSQLTQHAVTDVHKSFPSADIPMNKISNPHIRGFLEKYTKKDVPSQSTLRRNISDVYNEVIGKIRSGIGEPPIWLSIDETTDKTSRYVANVVIGALNKDEPSKPHLLMSRELAVTNNSTISQLVLDALVFLWPGQRNEEMSKKFVILLTDGAAYMLRAGKNLKKTYPELMHVTCLAHGLNRVAETIKDLFPLSNRMMASVKAVFKKAPSRILKYKEFHPNLALSPEPIQTRWGTWLVAADFFAEHFDAIKSTVDSLDKSDAASIKNAQNLLGMQSLRMNLCTCQLISRFWLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEM1</accession>
    <name>A0A1D2MEM1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="7">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001540">
        <property type="protein sequence ID" value="ODM91467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEM1"/>
    <dbReference type="STRING" id="48709.A0A1D2MEM1"/>
    <dbReference type="OMA" id="KFWRCGP"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF22">
        <property type="entry name" value="CRYPTOCHROME DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="8">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="247"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="287"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="384"/>
            <end position="386"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="506" mass="59252" checksum="EA9EC5D15A5A2D88" modified="2016-11-30" version="1" fragment="single">CLVWFRNDLRFHDNEALLWAHEHAEFVIPVFCFDPRQFETTTHRYKFPKTGNYRAQFLIQSVEDLQKTLKEKGSTLLVFNKRPEVTLSSIYDVCKYDAVVFQKEVTSEETEVEEACELFCTKNKIQFRPIWGSTLYHKDDLPYTVKNCPNTYTQFRKDVEGRSKIRLEQPMPKLLKHLPPELTEISEELPSFEKLGLVEPTVHANTAFPFTGGETSALNRLQSYLWATGAIENYKTTRNGLLGSEYSTKFSPWLAFGCISPRRVFFEIRKYEKERVKNDSTYWVIFELLWRDYFRFIAIKFGNCLFFSGGVKKIRYKWEEDMEKFRKWADGKTGVPFVDANMRELLHTGWMSNRGRQNVASFLTKDLKLDWRLGAEWFEYLLVDYDVCSNYGNWNYSAGIGNDPREDRKFNMIKQATDYDPEGAYARTWVPELGGIQGGKIHVPWVLRPGELGSIKLGVDYPNPMIVAQEWRRHFDKTKSPGWTVSTKNKQKGIDFYFKSNTSSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF99</accession>
    <name>A0A1D2MF99_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Failed axon connections</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15014</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001454">
        <property type="protein sequence ID" value="ODM91667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF99"/>
    <dbReference type="OMA" id="YSRWKDE"/>
    <dbReference type="OrthoDB" id="8250323at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03193">
        <property type="entry name" value="GST_C_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="3">
        <location>
            <begin position="66"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="2">
        <location>
            <begin position="212"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="32904" checksum="EB35969669840981" modified="2016-11-30" version="1">MGCCSIELSLTNLVLFGVLFFIGKKAIKFFQKWKVEKMLEKWDEAPKDKLILHTVWRSKPMPSVSPFGLKLETYLRMAKIPYEVLNNNLDTTDPMGPKGKLPWITYQGVHVADSQLCIEFLNKKFDISLNKSASKEQLAAARACRVMLEDHFLWGLVQYRFVDNINALSQLMKIPGIFKLLLPIRSYQLKQRMISNGIGKHTPTEIYQMTGADLHTVSAVLGSKKFFGGDEPCEDDCALFGSVAQAVWGLPGSSFERLCQGELKNLKEYCVRMKERYWADWDDCRDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFN6</accession>
    <name>A0A1D2MFN6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">THAP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14969</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001446">
        <property type="protein sequence ID" value="ODM91712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFN6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFN6"/>
    <dbReference type="OrthoDB" id="6783781at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006612">
        <property type="entry name" value="THAP_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05485">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00980">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50950">
        <property type="entry name" value="ZF_THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="THAP-type" evidence="7">
        <location>
            <begin position="35"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="339"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="360"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="969" mass="107739" checksum="7C71B0077EF3256D" modified="2016-11-30" version="1" fragment="single">MAAIHAYPARKYRSEMGWHLLIFEYRDLKYLDSKMSGTVCSYSGCKRSYSADKDVSFFPFPGDPKSRCYGFVFQFCRRKKWMDNCGNTELKDMDERQLRRKRICSDHFILKAFSRPESRTALNDTAVPIPAKKPPATKQSTPAPVATKSSAAESPATPKSGEGSKKPPPKLQKRNSKIDPPTPKASEAENKKNSGANLEKKTAEEQPVAEPEKVTTPASTSKNSDTSKRVTRSPKKSLKPDNVPSKTSETEEKKSTSGDLKQKEAEKVPPAAASPLTPENQKITTPVSSPKPIESPKKSPVKFAKKSKPGPPTPKPSETDGKKDSSGNQVPKSSEGVATESSKSVTPVSTPKSSESPKKPPTKVQKKILKPGALKRKPPEADEKKDSSGNVEEPKKSKVETAVPVTNEPQNISTTAIEIIKKNVPKLKKIMKTGPSKPAVLTILEKKSIVKTDSVKKTGSEATKSTVTELSKPGSAPTKLIKKVVKTQASSSDISKVVKKVVKTDPSSTDASKLIKKVVKTDVSSVGIPKVLKKVVKSEASRPKLPFYPDACTELSTLDSQQGPDENLFEGFYVSLKRFLKLSGRWTIGGVQWDPQGKRKVIMVSEPEISPNGRPCVKRCLQFFEDKALKVFIDGLDMTDVFEMNSYADKEDVAALICRVAEASSCCGVPEMISDDLPNFPNAKKRSTSYFDSECPGIIPNDSFDAICSACKKLRSRVLECRQQEKKRLNERRIRSQEKEFRHPFGEALYTMFGDLVDETDPSKPKKKRNKETFFRKFLTDTRYKMNGDAGRTERIYVEKPISYRKVSKILYQNLDFPCRMLKRNHHCQEAPVKGLHLQCFLLQDLESWQEVQQRKMSMMDTGLYTGHTRSFTDDGQEYELIAEVEPGSTELVEMKPNPNQYEIIEVDDETLAKLASSRNQVVMLPEAASSSSSNIVTRIDANDPNLSQILKAINTSQARMSEESYFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFP4</accession>
    <name>A0A1D2MFP4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DDB1-and CUL4-associated factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001449">
        <property type="protein sequence ID" value="ODM91704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFP4"/>
    <dbReference type="STRING" id="48709.A0A1D2MFP4"/>
    <dbReference type="OrthoDB" id="4869960at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045151">
        <property type="entry name" value="DCAF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574:SF39">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="228" mass="25330" checksum="AE9B75A458349F0B" modified="2016-11-30" version="1">MSVGSECERNSSTIPLDTEQPTSSANAKRMWKESEKMKTGGKILMKFTGHRNSRTMIKESNFYGEKYVISGSDCGHVFIWERSTGHLVQVLEADNHVVNNVQPHPFDPIIATSGIDYDIKIFAPVAKANTFNMIKARELTHRNEVMLAETADTITVPAAFMIRMLSCLSHIRRSNTQASAAAAAVAAVEESNDEAPAIEPPPPPEEDVARKRDEDSRHNDDEDDDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG25</accession>
    <name>A0A1D2MG25_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001376">
        <property type="protein sequence ID" value="ODM91948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG25"/>
    <dbReference type="OMA" id="LYIMETI"/>
    <dbReference type="OrthoDB" id="10567261at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903957" evidence="1">
        <location>
            <begin position="23"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="35407" checksum="93A8C668CECE92F7" modified="2016-11-30" version="1" fragment="single">MKFITRNIFILSLSLLVNFCECSSRPSGSSQTPPPLYNIKNVENYSRWCKKSSPEVFFNNVAEPSLTLLYHRGKALFGILMDKIEASYDDSEALEKAREQWEFIFKTVTSSLDSALDRLESEWVHFILLHDTNPLPWEVLYKTTLTHEVLDRLEYGYMMIEAVMRSGVKEVVGSLQHQLVQVIRKLEDEISKTSDSGEDVTELQLLKKMKRGLSKMKPSFTTKLLEKVLAKALKSKDAPSQSNFISSTMDEMALVIHAYREKGSQFPNFWTEISLILSKGKRNTQSEMEEGVSNFIQELLQNQEALIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGH8</accession>
    <name>A0A1D2MGH8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001337">
        <property type="protein sequence ID" value="ODM92075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGH8"/>
    <dbReference type="OMA" id="REQEIMG"/>
    <dbReference type="OrthoDB" id="10645688at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="19435" checksum="B1AC12C35867F114" modified="2016-11-30" version="1">MKGVDKDKAKQLQKSLNQTYEEDSDDEMPEAVSNASMKSDYELLSKQISDFKDKLRQEKKAKRREQQEKCIAQKKVKIDASEQFNDEQTSKAEDEEKLASDETVTVDKAPAKPTKKVYPSLNITVEPLNKIQDSRASLAIDFKSRRLAKVPRESVKVGVIAYQKKLQVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGR8</accession>
    <name>A0A1D2MGR8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear respiratory factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001303">
        <property type="protein sequence ID" value="ODM92179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGR8"/>
    <dbReference type="OMA" id="EESDNAN"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="53873" checksum="01D83E180A2E564B" modified="2016-11-30" version="1">MTPLEMLETSKMANGTPNEEKKKKQGLISRLPIPFVKGQPADIQKMNVENLRRFINFACSCCEEVDLPNSANPSIQTPLWWPTAITFDKSLKLRRGLKSREHQKHLALLVWKLYESYGFASLLAVSAELSDSRSKRFTLDKGPINWKVVDAIGRTIAVVDQRTRAYDANPRVVLEPIPNLNSVKEILQTKQVKKVLPKRNSKVKRALFESENEDELNNCKFCLKHFTYREFCEDHEKVCPKGPPKSEPSQESFLSSLGLHGISRRKEESDNANSDEVAPPAIHIGRTLRKLPKRNQLLSLIRNNPIPITSGPGKRFLSELAEKVEISYPPAYEICCKPKSGMGMSEPKFATVTKRTILKDGENPHVYSQGKLQRTKRYQELVVGLSESSWPAFNKCKRARLCLEKVDCTTKKIKVKECVATTSYLQRRFNAALSPQVKLFDIMKFPLSKGSWGSAAPLKLPKEIEMVQTDTISAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHK2</accession>
    <name>A0A1D2MHK2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001241">
        <property type="protein sequence ID" value="ODM92401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHK2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="26031" checksum="D69178B894548724" modified="2016-11-30" version="1">MGGQEFRNGFGNAQFPNYMAVAGAPEGGSESQRVILTQNSALNVFVMGPGNVTINLGFHVDAAAAQGRMASQMWNNVGITTHPQQEQFQPPSSFGATSTGTTFPQSGSISELRNSRLSPGATIHPSKLGTTPQEYGSAVNMRKRLSVSALSPISHSPPNGNSPQDLIRKSPDSGYNSPSQAEIIPPCNSINFPADVRVGFPSSSSSFFPLTTGFGPINYFLISHSTFLSNYNSLGYLFHHFTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHL1</accession>
    <name>A0A1D2MHL1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein Wnt</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14216</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Ligand for members of the frizzled family of seven transmembrane receptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
            <location evidence="1 9">Extracellular space</location>
            <location evidence="1 9">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Wnt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001221">
        <property type="protein sequence ID" value="ODM92466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHL1"/>
    <dbReference type="STRING" id="48709.A0A1D2MHL1"/>
    <dbReference type="OMA" id="NVECDEC"/>
    <dbReference type="OrthoDB" id="5945655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005109">
        <property type="term" value="F:frizzled binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060560">
        <property type="term" value="P:developmental growth involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007517">
        <property type="term" value="P:muscle organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2460.20:FF:000001">
        <property type="entry name" value="Wnt homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005817">
        <property type="entry name" value="Wnt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043158">
        <property type="entry name" value="Wnt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018161">
        <property type="entry name" value="Wnt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027:SF98">
        <property type="entry name" value="PROTEIN WNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027">
        <property type="entry name" value="WNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00110">
        <property type="entry name" value="wnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01349">
        <property type="entry name" value="WNTPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00097">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00246">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM92466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="337" mass="38180" checksum="7EC2AC7591316BCD" modified="2016-11-30" version="1">MELCIRAPETTKVAIQGIHLAADECAFQMAKHRWNCSSLQGSTNPHGTQLFKKGYRESAFGHAIAAAGIAYSVAKACSQGKLLSCGCGFQYDDQVNYIPSKEADYAFDESNEAIFKKGSNSISSWKWSGCSHNMDYGMKFAKLFLDSREKSHDLPALTNLHNNKVGRVAVSANMEVRCKCHGLSGSCELRTCWRSPPEFRRVGLFLKNKFRKAIMIDQSELGNRPLSRVQKLNKQRRKRRDRQSEKRSNANIDLWYYERSPTYCESNKDFSIPGTTGRRCNKTATRGEMGSCSTLCCGRGYNTIRQVYTTRCNCQFIWCCQVTCRNCTVDEWITVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHU7</accession>
    <name>A0A1D2MHU7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001241">
        <property type="protein sequence ID" value="ODM92404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHU7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="196" mass="22324" checksum="BEC91918B0968D21" modified="2016-11-30" version="1">MLTQLLSTLETSLNHENGIYPANSIKKEGIDVEISHENDEDVASPLRKNVESRKREGVLAIEGGSFEVYWTSSESEPDMDSLECSKCPQVAFFSTDSEDGMELAYQKIKIHCLLMHSTEVWKNLGSPSSLIPCRLCNVVFKESPERDRHEFMHHKAYEILHGPGLLTEERVILDSKKNKQIMGEGLVFDPKEFYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML91</accession>
    <name>A0A1D2ML91_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">ADP-ribosylation factor-like protein 2-binding protein</fullName>
            <shortName evidence="12">ARF-like 2-binding protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12862</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
            <location evidence="1 12">Cytoskeleton</location>
            <location evidence="1 12">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 12">Cytoplasm</location>
            <location evidence="3 12">Cytoskeleton</location>
            <location evidence="3 12">Microtubule organizing center</location>
            <location evidence="3 12">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the ARL2BP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000907">
        <property type="protein sequence ID" value="ODM93819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML91"/>
    <dbReference type="STRING" id="48709.A0A1D2ML91"/>
    <dbReference type="OrthoDB" id="302784at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051457">
        <property type="term" value="P:maintenance of protein location in nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1520.10">
        <property type="entry name" value="ADP-ribosylation factor-like 2-binding protein, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038849">
        <property type="entry name" value="ARL2BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023379">
        <property type="entry name" value="BART_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042541">
        <property type="entry name" value="BART_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15487">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15487:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11527">
        <property type="entry name" value="ARL2_Bind_BART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7 12" id="KW-0969">Cilium</keyword>
    <keyword evidence="6 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BART" evidence="13">
        <location>
            <begin position="19"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM93819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="23037" checksum="A9A2BF3D9D1DE5ED" modified="2016-11-30" version="1">MATESKDAEASDKFNEAEFVKIVGLVEDILVDEDFQTRQTEYFSRHWKQFADENDDRAVPLDSSELQKLSTERFNIFRTYSIEMGGFLESELKRSLGEEFEIQDFLHEVELRTKQNETLMAQEKGSSGDKHSISPRVQQQQQEFETDGEIVDMLLTLRDFGRFQELMVDYSKMMQGKTPDMDGLVSYRKISDDEAETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLA8</accession>
    <name>A0A1D2MLA8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L7a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000941">
        <property type="protein sequence ID" value="ODM93634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLA8"/>
    <dbReference type="STRING" id="48709.A0A1D2MLA8"/>
    <dbReference type="OMA" id="RMVKWPA"/>
    <dbReference type="OrthoDB" id="29563at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="135"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="271" mass="30819" checksum="143B6735100F940D" modified="2016-11-30" version="1">MVQKKGKKKVVGKKVAAPPPLATKRTESKKQKNPLLEKRPRNFGIGQDIQPKRDLSRFVKWPRYIRVQRQKRVLQERLKIPPPINQFNHTVDRQTAKQLFRLLDKYRPETRAARKARLKARADSKTKGKDDAPTKRALSLKQGANSVVRAIEQKKAQLVVIAHDVDPLELVLFIPTLCRKMGIPYCIVKGKARLGRLVHRKTCTCVALTNVESGDRSQFTKLLDAIKTNFNERYDELRRHWGGGLLGSKSSARIAKIERAKVKEAAQKVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLN8</accession>
    <name>A0A1D2MLN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000919">
        <property type="protein sequence ID" value="ODM93764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLN8"/>
    <dbReference type="STRING" id="48709.A0A1D2MLN8"/>
    <dbReference type="OMA" id="ITTYIRI"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904224" evidence="1">
        <location>
            <begin position="20"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="95"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="272" mass="31923" checksum="23D1A1DFC57C7BC5" modified="2016-11-30" version="1">MKFLLCVLVAVVGFKFANSVSVEKDLTLTFREKQSLDKFRDRVKSLLKEDNQKTDIYLIRWLRAKNFNIDDAENMLKENLKWRKENNIDTIHLENFDDMEKDYHATIDTYDLEGRPVGVIDINTWDIRAAVIQGRGQRLLRWLDRLMENITDQVFERQAKGMNVTQWKVLINTDGFNLVTHGCPLCIPVWIQFIQSLENHYAGWMDEMIAIDAPSAVQVILEILRPFLSKSTRDALHIFSPNRTKWMAYLDERISRDERRPLYGGTKPPVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLW8</accession>
    <name>A0A1D2MLW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G protein pathway suppressor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000891">
        <property type="protein sequence ID" value="ODM93902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLW8"/>
    <dbReference type="STRING" id="48709.A0A1D2MLW8"/>
    <dbReference type="OrthoDB" id="10038194at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026094">
        <property type="entry name" value="GPS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22654">
        <property type="entry name" value="G PROTEIN PATHWAY SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22654:SF2">
        <property type="entry name" value="G PROTEIN PATHWAY SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15991">
        <property type="entry name" value="G_path_suppress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="444" mass="50193" checksum="5CA68375377C461D" modified="2016-11-30" version="1">MPPVVLERPKMSRQMWESLKSQIVRERQRKQQELEADAEVERQRKERERQQKQDSMTLSETREQIAALEGRLSELKDEKHQVFMQLKKVLNEDEVRKRQLISQEQTRFDMGRYLELGKWAIMLRNANDTGGPQMFLQQVTLTRPPTAVYKGVPVSHQPAPHSSHTLLPPGGLKRSRSPSPPLHQSNNYKFGPFKPPPHALHSYPHKPGPVGALQFFPSQAIQQQPPHTSQPSFSSGHHQPPPQQQQQQQQHNNSTTTTATTTAATTRYGVYIRWCSTFKVTSVSISSRKRRTTKAFHHLFAAYSFSTSRIRDASSGRSMFELHLSHQHTPPPQKFGDDSPKYYPPPTHSLPIRSTHMTIHPALSIQASQGISTGSITSGFPIRTQPSVTSFQGRPPSPHITYTGPGGPPRLSYGHPHSAHIQTSAPHPNAPRYNMPPGMQRDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMN7</accession>
    <name>A0A1D2MMN7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12349</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000821">
        <property type="protein sequence ID" value="ODM94336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMN7"/>
    <dbReference type="STRING" id="48709.A0A1D2MMN7"/>
    <dbReference type="OrthoDB" id="7544260at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811335" description="Metalloendopeptidase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="35"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="367" mass="41783" checksum="D06C789A2A9B4CA1" modified="2016-11-30" version="1">MNSLYTVFILFFQLLSLSVLTNCYICNNTDQEYGNTSYTNGSRWPNGVVKYKLHTSLSSDDKVEVQRAFDEYQRKTCIKFQPWQEGDKDYTSIETDNSICGQGHVCKQGGYQYAKFGGNCRESSTMIHELGHNLCLHHENERGDRDEYVNYSKCQRIPQKMDNGTFKKLYDFDSQMHLSCQRCDGGGWPKKHVSECGPDVNDGLSVLDADNINALYDCQGCYRHRWRPMTSLTSDDRSNMYHFGYYGKYGSRLYHAEAIEAEVLTIPGGLSREGFSYKLVSPFKYGDSELLQIGVPAGRVGRIPFDIERGTGYIAYTTFFGDDGAKEDTIGKVWNRAGELNVAHFPRGSTEMLVSDQEFYILTCSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPK5</accession>
    <name>A0A1D2MPK5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000743">
        <property type="protein sequence ID" value="ODM94832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPK5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="437" mass="50893" checksum="BE3107D2B4EF3E28" modified="2016-11-30" version="1">MEVSKEEFGTISVQKISLPEEIWDIILRDLTAKDFHAVTIACSEWDQVLHHKKGRILFPLILPDLVEYLPLQSVLNCRRLNKTAMNIIDSKLQCDLTNNIKLCRRRECKTVKTLNQQSYRFCVPTELLSFINKYDKYSFNPFLTRSVSLSGCVPENVEEWELNLLSFLAHFGHNIWSLDLHTDFGNGGRFLYAAKQINLLNYLPNLKQLKLSGFVWRKVEVKHLMRLGRLPDLKQLICLDVETSSWVVLQLLLRQSGPNLHKFHLRRMFQMSPELNWKRITKFVPNVKELKIIYDNAIVARSFPNLIGTVEWHLEKLGVESQAPLNLSDFIGVANQFSNTLVELEILTNLIENEDAQLLSHMPVFHKLKILRININSVNKSWFLNVLKHKFPNLIRLYIFMGRGFPETNITTIQTEIELLPEFKKINVQFHPIHLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQF5</accession>
    <name>A0A1D2MQF5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000707">
        <property type="protein sequence ID" value="ODM95132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQF5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20379">
        <property type="entry name" value="Tudor_dTUD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="57669" checksum="D2BC871C3412A2A4" modified="2016-11-30" version="1">MNRLSVKTLQQQMGFANDKEILPNGSKCNGIPEGVSLEPTKVPDRLMNQNKKIPVAVMYVDLDKQEVWVRFCDNETIGKRIAMEDSVRKFCESSDAENYLISPEQVADDEVVIVKDSSDNYHRTRIPTGSRNYLSSLIDLDGRVAGLKFESGDGKIYRIPAENKHLMLWHQAVRCKVALGKPESMTRTLWLQHNEFIFKNRQWIETCLLVALECSRCQVYIDVSNITREEGEITIYIDIFQTDKFMEGFFSAFRFRTIPRLPSVGREKVAVITNVQQQGLINVVMYDYVFNCLREVLKKLYSEKDNLFANAVAVDLAIFYREMIDGLQVKKFLALLPGENTQLHRVHVLGIEFQKDVRVLYIDIGKEMIVPLEYLVIPYEQCNNKNVPQMLELISPQAVTLVLNGFNDTTGIDRSILFGIRKSLEFKPCFLKVVFNSSFYNKHPIAVVRTDILPSEVVSVMDYVHSQAILYTGRLADETVLVNENNLKCLKNVATRLAFNNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQG5</accession>
    <name>A0A1D2MQG5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_11342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000683">
        <property type="protein sequence ID" value="ODM95349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQG5"/>
    <dbReference type="STRING" id="48709.A0A1D2MQG5"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="22"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="14411" checksum="43617960BEFB6C5C" modified="2016-11-30" version="1" fragment="single">IQAPFAEVIGYSVNKRECLRRAREESDPHVGRVNLQEQHRSPTSPNKRREYRRQQAETQQNAETQGHRDQNTLNLHARSGVEILATPCGHVYCRDCIFQALRDKPECPECLSKLYIQNLNTIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQH2</accession>
    <name>A0A1D2MQH2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Myosin heavy chain 95F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11528</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000705">
        <property type="protein sequence ID" value="ODM95152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MQH2"/>
    <dbReference type="OMA" id="LNKGCTQ"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030048">
        <property type="term" value="P:actin filament-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21759">
        <property type="entry name" value="CBD_MYO6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21958">
        <property type="entry name" value="MyUb_Myo6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.360">
        <property type="entry name" value="Myosin S1 fragment, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049016">
        <property type="entry name" value="MYO6_lever"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032412">
        <property type="entry name" value="Myosin-VI_CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008989">
        <property type="entry name" value="Myosin_S1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF745">
        <property type="entry name" value="UNCONVENTIONAL MYOSIN-VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21521">
        <property type="entry name" value="MYO6_lever"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16521">
        <property type="entry name" value="Myosin-VI_CBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02736">
        <property type="entry name" value="Myosin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 7" id="KW-0518">Myosin</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="11">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="10">
        <location>
            <begin position="64"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="7">
        <location>
            <begin position="552"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="993"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1187"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1361"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="744"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="817"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="993"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1366"/>
            <end position="1395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM95152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1501" mass="171943" checksum="BE82B7C886FF1505" modified="2016-11-30" version="1">MNHLLLMSSQKVWVSEPKEGFVLGCIIDLGSDRVTVSTERKIGNSSTIQVPYESVYPAEDDSHQDYDDNCSLMYLNEATLLNNIRIRFNKNQIYTYIANMLIAVNPYVDIKNLYSRETIMRYQGKSLGTLPPHVFAIGDKSFRDMKTTKQSQSIIVWCWKNGVNQVYFEIPLRVLGKCGSPIEQKILDANPVLESFGNAKTTRNNNSSRFGKFIEIHFEQMSKVTGGYISHYLLEKSRICSQSSSERNYHIFYQLMAGASSALKSKLGLEGKTLKDFRYLNRGLCEFFGQSLSDPIVHDIKDFQNLEKSLDHLEVGAGDRLSIYTVVASVLHLGNVDFEDDPDDTRGGCRVKDATEASLKLAASLIGVDIDELRTSLTSRVMQTAKGGLKGTVIMVPLKTYEAANARDALAKAMYSRLFDYILIERNPRGILSILDEESKLPKPSAGHFTSEIHKQYPNHFRLALPRKSKIKEHREIRDDEGFLVRHFAGAVCYSTAQFIEKNNDALHASLEGLVQEQSGNQFLKGLFGKASTQVSGKLVYVSVASKFRSQLAELLDKLRGTGTSFIRCIKPNAKMIQGVFEGGQILSQLQSAGMTSVLELMQRGYPSRVHFSSLYSTYKGLLPPKLSNLDPRFFCRALFKALGLSEEDFKFGLTRVFFRPGKFKEFDQIMRTDPESLKQMVSKVTKWIIHSKWKKSIYGALSVIKLKNKIVYRRENLIIIQKTARMYLAKKKHRPRIQGLSRIRNLNSQVQSLEQTAQKLKQNKEAGQGDVKKLQADLIAATQKIKSNPNLGRKEIEKLCQDLFSKCETLVKSMSQRAESERIAEEQERARKVREEMERQKREKEEQERARLLEEENRKKKAEIEARRKQEEAEMALKMKNQKTVGAKSEEDHASIVMLEQDKRDTELAMRLAAENNATVDYSSDTGSTGSGSLRRNNAVINSRAGKKYDLSGWKYSELRDTINTSCDVELLEACREEFHRRLKVYHAWKARNSSRNGGGPSSAASNSRGPDVMEETQRAPKSVYQHQHIYPPNAPSPTPSDSQRYFRIPFTKDGQNKGLWYAHFDGQFIARQMEIHPGRDATLLIAGRDDMQMCELKLNETGLTRKRGAEILEYEFEKEWSKGKKTLVGCNVNNSIANKNYDLSGWKYSELRDTINTSNDVEFWGACRQEFNRRLKVYHAWKARSNSKNDGEPTAARNSRGSNEMQVTYRAPKIVYQYQHIDPTSARLDRQHFFRVPYTEDDQNKGLWYAHFDGQFIARQMEIHPGRKITLMIAGRDDMQMCELKLNETGLMPWQGFEIIEYEFEKEWTANKYDLSAWKYSKLTDTINTSTDVELLEACRMEFLRRLNVYHEWKVGNKSKNDCEASTSCSSRDPNMMNETSKSVQQNYNSPNLSSSTTSESQRYFRIPFTKDGQNKGLWYAHFDGQLIVRQMEIHPGRDETLLIAGRDDMQMCELKLNETGLTRKQGAEILESEFEKEWSKYGGERYIRPEERETFAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQI4</accession>
    <name>A0A1D2MQI4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 35 member G1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11565</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000709">
        <property type="protein sequence ID" value="ODM95118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQI4"/>
    <dbReference type="STRING" id="48709.A0A1D2MQI4"/>
    <dbReference type="OMA" id="HWTIGAS"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="117"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="276"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="431" mass="47504" checksum="C735781CAED421C6" modified="2016-11-30" version="1">MEDDDNPKIPQKGQDQLRSPTGAPPKYENVKINTDKVVIIPPNPVFVKMGEVEDREPTERDKFQVQEEMEVFEGDPSLTVEGQVAFMTNSRLSLRGGGANRRISTVSNKALGWKRYLGLIYTLISTNMFSLSSNILKLMGHVHPLNLGAYAFPVAALLSAPFIWYTLKIEKKPVMTNLLPVCKNKKVVFFMWFRAMTSVAITYGLIASFKYISVADTRTILAASVITVNFFGWICLGEKCGVVPILVAVMALCGIGVMTRPPMLTGAESFDNETLIGVSLAFGCMILATIIILSLRFLQNVHHGVLNTFLYSWAFVSSIPFAIGFGKLEVPDNGWDIVGMLGVGVLWSLGNTFLVLALQAEEAGVVALIRTSEVIFTFFWQMVILHIYPDIISLIGAVLVLTGVIVVTLRKWVASLDSTSSLRKKLGFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR98</accession>
    <name>A0A1D2MR98_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lysosome membrane protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11360</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000684">
        <property type="protein sequence ID" value="ODM95334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR98"/>
    <dbReference type="STRING" id="48709.A0A1D2MR98"/>
    <dbReference type="OMA" id="MNGIFES"/>
    <dbReference type="OrthoDB" id="195015at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005428">
        <property type="entry name" value="CD36/SCARB1/SNMP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF51">
        <property type="entry name" value="LYSOSOME MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01610">
        <property type="entry name" value="CD36ANTIGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="246"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="276"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605428-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM95334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="483" mass="54404" checksum="C9BF3D88DA0551A8" modified="2016-11-30" version="1">MQKLPYILLGTGFFFLAVSLASWYLGPVIFGQPQQGGNNAEGQPTFNPSQFKTENYLKVYFFNVTNPTEVIAGQKPVLQEVGPYVYQEDSSRVMSSFDAEIGAVSYRDVEAFYFRPDLSDELREDDVVTIINMPYVGLVQEVSKLSSLSRVLIKGVITRFNEGLFLTKTVNELLFGGFRHELLASLSSITGEKYVPNNTFGIFYGRNNSNYGEFSVSMGLKNKGDLGKIVAWNNTSELEWWKDKKCRKLEGSYDGSLFPPGITQQTILRIFHPALCRTFKYGFKEEVVVRGIPGYRFTLLPSELADPRIRAENMCYCTNPGENNENCPKDGSYQLNACSKGASVSLSLPHFLYGSEEYLNQVTGYHPDESLHLSHVDIEPNTGLLLKLSRRVQVNLHLRPLRLFSDFRKVSNMLFPSIWTENTKEIPAPMAAGFMQKMYSAYIQIMLPTVVAGIALLIGLILVILALIILVIRVRKEKTKYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRQ6</accession>
    <name>A0A1D2MRQ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter G family member 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000624">
        <property type="protein sequence ID" value="ODM95757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRQ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MRQ6"/>
    <dbReference type="OMA" id="VVNQGRT"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038:SF3">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 20 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="11"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="20044" checksum="5B35DF0F8EF07953" modified="2016-11-30" version="1">MIDVSLYDSLTFYESAIFFGKLYNVSPQDVESQVKFLASLLNMTKLTDQIIGTLSGGEQRRVSLALTLLHSPDLLILDEPSVGMDPMLRKSIWEHLYRLVVNQGRTIIITTHYTEEANLSNMIGIMRNGRMLAEDTPSNLLSTFNCTLLEDVTLKLCRADERSTKMLLTLFRPAIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-11-27" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS90</accession>
    <name>A0A1D2MS90_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Magnesium transporter protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_10730</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000602">
        <property type="protein sequence ID" value="ODM95950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS90"/>
    <dbReference type="STRING" id="48709.A0A1D2MS90"/>
    <dbReference type="OMA" id="PMSANEY"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="357" mass="41278" checksum="48AB1D797EB66D2F" modified="2016-11-30" version="1">MLRNKRMSLMCTFAFVLVACNVFLTDTKLISKIDKAHPNEALMSRKLNKIVGMMDGEGNAIQGVIPMSANEYRELVFDPPRNYTIFVLFYNDNHICDKCQMVLTAFNKVADTFLRLNTKFDKEANTWYMPIAAFFVTVKMSEGYRNVMVDLDPALPNLYYFAPSLSLKYNAFEQMDKLVPEYGIFHEEKIPWWIEQKSGIQIFLEGEPSVALSNLYYIFAISIMVLFNVYHLGYWETLVNAIKNANYSYSISVIVVYFLSGQMYNYMNNRPVFGNRGLSLMSLVYPGSRQYGIESVIIMMLYGTIIYGIIQLVEIRERQLAERLRNSVVQQKVFSGLSCVYFGFMVIQFLFNLKTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSD6</accession>
    <name>A0A1D2MSD6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CUSTOS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CUSTOS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000606">
        <property type="protein sequence ID" value="ODM95926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSD6"/>
    <dbReference type="OMA" id="TCESIVN"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026694">
        <property type="entry name" value="CUSTOS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14482">
        <property type="entry name" value="CHROMOSOME 12 ORF 43 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14482:SF0">
        <property type="entry name" value="PROTEIN CUSTOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="175"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="25496" checksum="0B5909D46F948AEE" modified="2016-11-30" version="1">MKPPPPPRAKGPLGSLEIFIKGVDKTAEIGNSASKGGYLTNFYLMFDEDELRRMKSSSSDTDEEEKRKLASAVDPTFMKTSNSKCDNAGTSNSEQPEAPPSKRMKSSDDSVELNEFDKPYSLSVTPDCQKFIAKQLSESLEKNIKGISPPPLPSEAKEVSDTGIKLFATSQVHVTAKDLDETKQPRRKLGNRKVKKKYPNKNGTSHSSDSESEDERLKSVAVSADWVHQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSE2</accession>
    <name>A0A1D2MSE2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIP41-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000591">
        <property type="protein sequence ID" value="ODM96039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSE2"/>
    <dbReference type="STRING" id="48709.A0A1D2MSE2"/>
    <dbReference type="OMA" id="TRWYHEF"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="337" mass="38330" checksum="0BAD6AA781E90D5B" modified="2016-11-30" version="1">MEGRGSNDASNPKNPTSSSGRRKSNGNSVVGAVQYARRVNEQSYAFDGWQITVLKSPILPSNCYCNILDKDNTKGLLFELGCKLEDVNLPSKSSVESSDQETASTIKCHVCRYTEQLPLKHLPDMVFPDNYLHLRHEASGLILEFNTLEAMKLMSTQDTESLQIACSKDWQASQTEMGLPKEVLHDFNWTFSTDYNGTLKSSQAGNEVAVINNPSEEINMEKLKQREQILFYDELTLYEDELHDNGISNLNVKLRVMPSGFFILLRHTLRVDHVMARVCDTRIHYEAGNNYFLRQSQTKQESFKNLAHMDPHQFSDINALSQFLPVTKETIEKILIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSQ3</accession>
    <name>A0A1D2MSQ3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glutathione transferase</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_10934</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily. Mu family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000626">
        <property type="protein sequence ID" value="ODM95745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSQ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MSQ3"/>
    <dbReference type="OMA" id="MAPTFAY"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042178">
        <property type="term" value="P:xenobiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000101">
        <property type="entry name" value="Glutathione S-transferase Mu 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF222">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="93"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM95745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="26317" checksum="FFDB75B99BF04FCD" modified="2016-11-30" version="1">MAVSKPLLGYWKIRGLGHPIRFLFAYLEVNFEEKVYELTPELTYDNWYADKEKLGLDFPNLPYLFDGDTKITEARAILKYLCRTRKPELLGKTTEIQTRIDMVDNFVYDLWYIEFSEMLYGYTEEWHKKYKAIEVVRLDRLSKFMGENDWSTGNDITYVDFFLYEVLYQFKKFDAGCFEKFQNLDGFLTRFENLPKIKDYINSPDFLEGPCINIIAKYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MST3</accession>
    <name>A0A1D2MST3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Magnesium transporter protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_10728</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Protein modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000602">
        <property type="protein sequence ID" value="ODM95961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MST3"/>
    <dbReference type="STRING" id="48709.A0A1D2MST3"/>
    <dbReference type="OMA" id="IFQQMNL"/>
    <dbReference type="OrthoDB" id="67566at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015693">
        <property type="term" value="P:magnesium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000009">
        <property type="entry name" value="Tumor suppressor candidate 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="341" mass="38238" checksum="FC1D628273E80C06" modified="2016-11-30" version="1">MMATSIDSRKLFSVIFVISVVILVTLNNVADANKRNKDVNALSLGERVQQLTDFSNKRPVIRMNVQKFNDLVKGTPRNYSVIVMFTALSPARGCAICGPANDEFSIVANSFRFNSQIYSNKLFFALVDFDECGSIFQSLKLYTAPVFIHFPAKGKPLSQDKMDIQRFGVEAEAIARWIAERTDIQIRVFRPPNYSGTMALIIVSVLVGGLLYLKRNNLEFLYNKTAWGIASLFIVFCFTSGQMWNQIRGPPVVQRTQNGISYIHRSSQGQLVIETYIVFLLSSAITIGMILLIEAGKGKGDIRKRRVMLVVGLGMFALFFGMILSIFKSKAHGYPYSFIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT17</accession>
    <name>A0A1D2MT17_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[histone H3]-lysine(36) N-trimethyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.359</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_10498</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.359" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000567">
        <property type="protein sequence ID" value="ODM96183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MT17"/>
    <dbReference type="OMA" id="THKGIKE"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140955">
        <property type="term" value="F:histone H3K36 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19172">
        <property type="entry name" value="SET_SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.100">
        <property type="entry name" value="Set2, Rpb1 interacting domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044437">
        <property type="entry name" value="SETD2/Set2_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042294">
        <property type="entry name" value="SETD2_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013257">
        <property type="entry name" value="SRI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038190">
        <property type="entry name" value="SRI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46711">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46711:SF1">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08236">
        <property type="entry name" value="SRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AWS" evidence="15">
        <location>
            <begin position="438"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="13">
        <location>
            <begin position="493"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="14">
        <location>
            <begin position="617"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="12">
        <location>
            <begin position="1099"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="171"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="223"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="644"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="903"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1127"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1179"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1225"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1384"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="277"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="664"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="903"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="915"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1144"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1197"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1243"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1263"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1385"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1400"/>
            <end position="1413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM96183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1513" mass="169650" checksum="629EBCD61E6974CC" modified="2016-11-30" version="1">MQRSASPDITDIGASLNRNVGRPRKPQPTPTPVTSQPSSSPQDVLPAPANDVQVPEQSPPPVVKRGRGRPKKSIDLVQPIPVSPATPPTPPPTGKRRGRKPKASKETVESPNIDVSEPVPEDMDISDGPHQLTDLNIRKDGVDSVVTKMETEDIPETSSFFSSILKSEQPFGQQTGVGIPGLDLNDGDGSSNAPFVMDNPISFPFGASSGVDEECKSLQQLSISNKVKAPKSTVDTEVKTEEATDTNEENESSKVRRSSRIKTLEERGSRGRRREVVSSLSDCSGISRSNLSLNEDDSNSNSSFNTGGTTSGYSSPSREYAGSSLANSYSTPNLHALGTSSSANSSSKPLKVKSRWRYSLDAESLKSFNSSGDSGVSDSCVGSNAVEEFMRPENCVQRSGHLLFDGTDSELLEKLKRFEGIDESIYKNEGRKKLCKEGKGMSCDCQLTNEDLIRGETGCGDDCLNRLLMVECGNECVLGKRCSNKRFQRKEYAPLEVFKTEKKGHGLRTLNAINEGGFVIEYVGEVLDVNEFEKRTTAYAKGNLEHFYFMALKSDAIIDATQKGNCSRFINHSCEPNCETQKWTVNGEVRIGFFAIADLRPGDEITFDYQFQRYGKKAQRCFCMADSCRGWIGDEDDDAELAEEKEKDVSADVEEAEVEDSKVKPKPKAEKKKRKNVQLEDMAFREELAKLETSGLKNRNHTLTLSRLMVRAESWDDRERLLKVLINGGTPCRRLFLDYHGLRLIWSWMVDLPLPHENGGPQLIRNDIYHTLFLQALQSLPIPNKTILLESKVLSLIEKWCTVPPVTTCITLVKRTEAPVQVDVKIPAVDSAATEEVIVKTEANEEKMDTSEIKEEPTSTVEGMQELVEEQTWGFVAISKSVLDSWTDLKEVFRIPKKERVEQMKEHEREADKGQQLSQPSVTALNNSYERDHRNKQMHRNRGERRVPVLDPTQNQFHRFQNRMVMPPGFSKEEWRRQFEQTVKQQEEQELLRKQQDALVILHQERCALVGLDPSITPIVDPHGVHYLDPKTVMWRPINVEDPSMPPELIKFLQLSQHPAPASDIPLVEPLVIVPEVESETGYPPWPEGLPGPPPLPPRELPKNWKMAIDDEGRCYYYHTRTKVTRWDPPNPYDVSSSESSESSTEEEEEEDKIEEASEGSPSISKASIQTWRTKLIERAERRKKTGLVQERIISPRGEDDKGFSKEMVKENKKKVLEEKLAARLAMKSEENSETETLTPTAESKKDNATEIEKDTKSVVARKVSHPPRKKSSSQGRSRRKDKQVSSKSAPKPKPKVTSRPDDSARTSASSSPIETELDLTLSQQNLDEDDETFLSRVPPTAGPSRIITSTPSMDVVIPGLGYDSRDIKHMKDKKVADKADRAARHAAKKKAMHQKKAKEKAAAEAADKDKRVSSKEASCIKDSFRNSIATVVVAHLNPYRKNEHIKNTDDFKHLARKITHAILLKELKHTRDVHSLEVTDSVKHKTKEYIKKFMARFPHGVYIRSPEQTQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTG5</accession>
    <name>A0A1D2MTG5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10347</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000549">
        <property type="protein sequence ID" value="ODM96333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTG5"/>
    <dbReference type="STRING" id="48709.A0A1D2MTG5"/>
    <dbReference type="OMA" id="IQYNACP"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF6">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904522" description="CUB domain-containing protein" evidence="4">
        <location>
            <begin position="31"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="171"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="467" mass="50688" checksum="70733F9B04FD0AF9" modified="2016-11-30" version="1">MCSSNNFSVKVALISILVVCFVDIVSLVNGDAVIETVPAVGLDSSEVILVRSKRQLPFLSNWWSTPSYKSNKIESSVQSYGNGNYHGKHRHNSHGHANRTSGLSAGTGVSERDPRFLSLFTIIKFDNSACLSASGDNGTCYPAAECNKRGGAANGKCAQGYGTCCVFSKSCGASTNQNCTYFTHNGYPSSYDGTGSCQLTVYKCSPEVCQIKLEFDSFNIAQPSPNGVCNNDQFIVSGSTTAVPIVCGVNTGNHMYIDVGVDNSPITLSVITSGPTYSRSWKVKVTQIRCTELGRAPEGCLQYYKGVSGVIRSYNFDFTAGQQLSNQDYTACIRVERNFCGIRYTACNDNVQFNQQANQRTRAFSLNGQNAQTQIGAMVGATSCVADWITIPCATNSGRVTQQGGAICQDRICGDTFNSEVSMQQMPVYSYAKPFRIHYHTDGNETNDMGNRGYCLNYIQQPCTPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU64</accession>
    <name>A0A1D2MU64_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Macoilin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Transmembrane protein 57</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_10210</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of neuronal activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Rough endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000537">
        <property type="protein sequence ID" value="ODM96472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU64"/>
    <dbReference type="STRING" id="48709.A0A1D2MU64"/>
    <dbReference type="OMA" id="KQRTACE"/>
    <dbReference type="OrthoDB" id="10071111at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030867">
        <property type="term" value="C:rough endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023041">
        <property type="term" value="P:neuronal signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019130">
        <property type="entry name" value="Macoilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47464">
        <property type="entry name" value="MACOILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47464:SF2">
        <property type="entry name" value="MACOILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09726">
        <property type="entry name" value="Macoilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="205"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="575"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="409"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="581"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="621"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM96472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="639" mass="71629" checksum="90EC19A9CCC5936B" modified="2016-11-30" version="1">MKRRNVDSSKARRPVKKIPKIYDGFYTSSLVVYVKLILLWICVMGGDFILEFRLEYLYPIYLLLHNSYEAYKFQGLAFALLLICIVVSVDVICLGVIPAPWLYLLGSLAVWGQVGWNLTPLGPLLLLPTLIYIDGKSIRPLPSQPLSPLAAHCVGFPLVSLGFGLKSYIGARLKQRTRNDVARQNELLYSLLWEALPLTSTPVNNNEVINGGPPVLAKKQQSPQAPRRKSLENGDGSREPSSGELVLVPTQNGKLPGAANGSSSGSSNSSSSPLSSHHNQNNHHNNHNHSNHSSSSSGASPTSPIQANSVQNHSHSNSSNHNNSNHYATPCPTCAANMLAPKKKKDDCCLKVESEVRKLRSDLHVVRTIESELRGQIASLLSSERNLRSDLASVQGEHESLQLKYSALLSKGQEERQSYEKKLQEERRLKENAITKQKKASSECSGDCRRKLREADREKESLRREIKVLEDKNMRIERELQNVKSTLLLEQKNKECSAEAARLRSLLTSLQDQNAHLESSLSAETRLKLDLFSALGEARRQLSIRENLIKSKEEELEEVRSQYVELLAVSDFSHHQHRHQQQQALQRQHSQTPQQQQQQQQQHQQTQQSHRLKAMVGVGESSPQQVGRENLTFTPLIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUF1</accession>
    <name>A0A1D2MUF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chorion peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_10131</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000527">
        <property type="protein sequence ID" value="ODM96552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUF1"/>
    <dbReference type="STRING" id="48709.A0A1D2MUF1"/>
    <dbReference type="OMA" id="GYPMERL"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09823">
        <property type="entry name" value="peroxinectin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.640.10:FF:000003">
        <property type="entry name" value="chorion peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904569" evidence="9">
        <location>
            <begin position="26"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="666"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM96552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="916" mass="103962" checksum="A7B9F02CB8AACAC7" modified="2016-11-30" version="1">MSGSEKFKRLACLAFFVIVIVGCSANVGTPTEIFNKTDLEISESNPKVVGVKKHKNYEIVVYEYDESGEGKDGKNKDVDVDNPEITDNSVEIPIMDHPTSAPTKKSRGSSSSTSKPNLSHDSESDEEPKKNTTAETDDVWGIDKALKCEDPTGKPGICQEYARCSIFYQELLDDYDEPIEPADYKCRLPTQVGICCPLVSEDDVISEPERKSSFKPISVGKRKQKRKVINPQIRRLIRTNLNNSFDYGDFFLEELHGIEQNLLSRSVQVSRNTPEFGHNKFFPTSKRIRQISDIGLSLLQTSNDISERLQLTNEIGGRGLKNFKSSNIEALNDRCPFQRPCRTSKYRTSDGSCNNLQKPKMGQSLTPLARILEPVYADGRWVPRVSVRGFELPSARLLSQSFIGDRNLPDNRYTLMVMQFGQFLDHDLTSVPVFTFANNSGINCCSNGRFLSPDLRHPNCFPIEIPSSDPFYSRFGQRCMNFVRSRMAPRIDCSLGYADQMNALTHWIDASNIYGSTDEQTRQLRLFQGGLLRFSELGDGKMLLPVRNTGQGVVDYRAGDDRVNEMQGLMIMHLVWFREHNRLAFELARLNPFWSDEELFQEARRITIAEYQHVIYNEWLPIIIGRKYMEKAGVVPLTKGYYKGYDPKIDASIANAFSSAAFRMGHTLVQGLVRLIDEMGRDNEVSVISQNDENTVRTRQPNQVDKWLRGMAQQPTQSYDPFITEHLNGRLFQGSNGAFGMDLSSLNIQRSRDHGVPGYNSYRELCQVGRRARTFDDFKDWIAPETADRLSLFYAHPDDVDLWIGGISERPLPGALVGPTFACIIGDQFTRSKKGDRYFYDIADQVHSFSPEQLGEIRKVTFARILCDNGDDLEALQPAAFLQADFDFNSLVDCKRSTRIPRMNLRLWQKEPTPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUJ1</accession>
    <name>A0A1D2MUJ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000525">
        <property type="protein sequence ID" value="ODM96568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUJ1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="388" mass="43235" checksum="B31BDB668A207C48" modified="2016-11-30" version="1">MKDLGNPVTNGVLHTILETTGVPASNMESFDCVVCLETVGSTPTRCCESSSHPICQPCFAFYQSKMRKPEDVLKCPFELESGAICGSRLLKVDDHDKLVVQPPTDDIMGRRFTDCQTIFGPFGSRVPLLRLAVNYGGTDLCMLMVDENRTYLRMWLCEMHPMVEKKSPATSYKMLAPYKPKVLPKLTCDFTGQIQPFGTTGPVTDGDDEDGGPKFFTMTKTFLRRARDKAKDVSFKLLIQFMKSDSAAEDGPVDMELGTEEKSNSDEVEKEVEIQKPETVSAPEEIEVDGKEEVTPASEAKTEPTPGTSSEVQPVPEASYKPPKPLPAVFGSYGPERKKTKPKPTVSKQSSTSSNPETFDFGLMLIPDADRYDEEELEKERKKWRPKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUQ3</accession>
    <name>A0A1D2MUQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA delta isomerase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09952</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000508">
        <property type="protein sequence ID" value="ODM96736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUQ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MUQ3"/>
    <dbReference type="OMA" id="YMRKFSR"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="303" mass="33877" checksum="39F9D2D839779FA7" modified="2016-11-30" version="1">MSSSMPAINLLRFSKLTISCKNFRHLPSVALIGGFSKRQFSVSPKTQTDKVLVSVENGVRKIVFNRPEARNALQYEMMDKIGNALFEANSDSATKLVTVTGTGEFFSSGNDLGNWHTANQTIPEIKEKTRRYVMQQLMFGFIDCRKPIIALVNGPAIGAGATMLPFCDQVLASDKAFFSTPFPAIGIVPEFCPSYLFPKIMGYSKANNMLLFCHKLTAKEAQECGFVTRVFPSESFAESCKKLIDAYVQLPTEPMLQAKELIRAPEREKLKQICAYEMDLVIDSIDSPHVRSNIDNFFARKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV65</accession>
    <name>A0A1D2MV65_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase II elongation factor ELL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000480">
        <property type="protein sequence ID" value="ODM96990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV65"/>
    <dbReference type="OMA" id="CMERISC"/>
    <dbReference type="OrthoDB" id="10617888at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904597" evidence="3">
        <location>
            <begin position="23"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="33615" checksum="B501BB1636F05A12" modified="2016-11-30" version="1" fragment="single">DLWLTTLCVLALVSFLKCGVICEQRLSSASILNNEVVGLPTSGGVSGSGSNDNSKQHTTSFVASGPTPNDEYRASYFYPASHHPQHHGVNWNRDTYADAANDFGYNQQQPHHQAAATNPGAVYAPAYGSTGESEGYEDSLGLGSSLGGGLGGLGGLGGVAGILGIKGLKGLGILGLFKAAIPILAILLPALLLIPLIFLFFPVPVITVPATGQRGLMGAFNLGEISGKMTNLARSVLESDKCMERISCEMSRVSRGSFIDRTLKRVLPRFEPHMPQVLKRFARVFLEQPGGTSCNKKYNCYLMDDSSSSTAKKSTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWX0</accession>
    <name>A0A1D2MWX0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclin-dependent kinase 7</fullName>
            <ecNumber evidence="4">2.7.11.22</ecNumber>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cell division protein kinase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_09136</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="4"/>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000433">
        <property type="protein sequence ID" value="ODM97546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWX0"/>
    <dbReference type="STRING" id="48709.A0A1D2MWX0"/>
    <dbReference type="OMA" id="GIHHCHR"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07841">
        <property type="entry name" value="STKc_CDK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000097">
        <property type="entry name" value="Putative cyclin-dependent kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000190">
        <property type="entry name" value="Putative cyclin-dependent kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037770">
        <property type="entry name" value="CDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 20 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 24" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 20 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 22" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="23">
        <location>
            <begin position="15"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="19">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <begin position="21"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODM97546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="347" mass="38846" checksum="44C820AA28A5C98F" modified="2016-11-30" version="1">MANGTGVKLSSDKRYEKIDFLGEGQFATVFKAKDLEEDKIVAVKKIKVGSKAEFSDGVNRTALREIKLQQELHHPNILGLLDVFGLRSNISLVFDFMDTDLEMIIKDTKIVLTPGNIKAYTIMTLQGLEYLHSHFILHRDLKPNNLLINSDGVLKIGDFGLARYFGSPNRLYTHQVVTRWYRAPELLFGARNYGEGVDIFAVGCIVAELLLRGPLFPGDSDLGQLAKIFEVLGTPNDNNWTDHKALPDYCEFNPTNPIPLRDIFTAAPDDLISVVDKLLRLNPNERCSAKSALQMPYFSNKPGPTPGHLLPLPSNVVRQQEEKPSLKRKLLEATDTSNSNLVKKLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX78</accession>
    <name>A0A1D2MX78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 3A31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09033</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000425">
        <property type="protein sequence ID" value="ODM97640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX78"/>
    <dbReference type="STRING" id="48709.A0A1D2MX78"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050705">
        <property type="entry name" value="Cytochrome_P450_3A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302:SF15">
        <property type="entry name" value="FATTY-ACID PEROXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904673" evidence="7">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="11406" checksum="FA65E924F5AF3AB4" modified="2016-11-30" version="1" fragment="single">LFYFLVVLLAALIIREGRKKYGVLEQSGIPVIEPTLFLGSEPNIHKTVLHLADIERFNKYGPIWGSYIGKNATFLLRNPELIRLIFVKDFSTHFGEPTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXW2</accession>
    <name>A0A1D2MXW2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trifunctional nucleotide phosphoesterase protein YfkN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_08849</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000406">
        <property type="protein sequence ID" value="ODM97832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXW2"/>
    <dbReference type="STRING" id="48709.A0A1D2MXW2"/>
    <dbReference type="OMA" id="GETWYDF"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07406">
        <property type="entry name" value="MPP_CG11883_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041821">
        <property type="entry name" value="CG11883_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="13"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="6">
        <location>
            <begin position="299"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="602"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM97832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="626" mass="69807" checksum="ACA41FDEC57BB1CB" modified="2016-11-30" version="1">MSESEGQKSIVLIHFNDVYDIESQKKEPIGGATRFCTAVKKYASLDPVVLFSGDCFAPSLLSTFTKGEQMVPVLNHVNTACAVYGNHDFDFGVDCLADLVEKTNFPWLMSNVIDKETNAPLGDGKVTYVLEKNGKKIGLMGLVELEWLETLATIDPESVIYKDYVEVGNDLAKKLKNEGCDVIVALTHMRFPNDCRLAENAQGIDLILGGHDHVYDVKHINGINVVKSGTDFRDFSLITVSFNDANNNPQFNIERISVTSDHEEDPALKADLAQYIEMMSTKLDDVLGEFTVDLDGLFETVRTKESNLGNFVCDIMLASCNADCALLNSGTLRSDRIHPSGQFTMRDLMTVLPMLDSLVVLKVSGSQLIEALENGVSQYPKLEGRFPQISGLRFAFDPSKQSGARIDPKFVKVGDEYIQPHQFYRLVTKEYISTGHDGYNVLATAEVLADSDQCLELSIAIQNHFHAIEMVRGHTRRNSRHHQSLITMSRRHSLLRSMTSFHEMSAAGPTSLERCNSLSPRPSLSRQGNVVEDMEKSSCRLAPQVEGRIVVVKNKEILQDLINERKDWEASRAIKEEEDENLSPTTPTDQLYRLRSLHLAALNRQESPEPYSRDPSPSIVLTPSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYB5</accession>
    <name>A0A1D2MYB5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitogen-activated protein kinase kinase kinase kinase</fullName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_08685</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000391">
        <property type="protein sequence ID" value="ODM97982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYB5"/>
    <dbReference type="STRING" id="48709.A0A1D2MYB5"/>
    <dbReference type="OMA" id="QRISKPM"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008349">
        <property type="term" value="F:MAP kinase kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06613">
        <property type="entry name" value="STKc_MAP4K3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000031">
        <property type="entry name" value="Mitogen-activated protein kinase kinase kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021160">
        <property type="entry name" value="MAPKKKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF18">
        <property type="entry name" value="HAPPYHOUR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038172">
        <property type="entry name" value="MAPKKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="15">
        <location>
            <begin position="546"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="319"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="442"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="452"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="26"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038172-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038172-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM97982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="906" mass="102370" checksum="2F3F29096C4C7112" modified="2016-11-30" version="1">MAQAQTISADISRRNPQDEYELIQRIGSGTYGDVYKAKRLSNGEFAAIKVIKLEPGDDFAVIQQEILMMKDCRHPNIVAYYGSYLRRDRLWICMEYCGGGSLQDIYHITGPLTESQIAYVCKETLRGLAYLHALGKMHRDVKGANILLTDGGDVKLADFGVSAQLTATLGKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELAELQPPMFDLHPMRALILMAKTSFKPPTLKDRDKWSVNFHNFVKVALTKNPKKRPTAERILLHPFLMGDLTKRTALELLHKVSNPNVSFYDMDPDEEGTVQNVPHRIASRRTDRVDQRTPSEIRNVTPDLGQRRRHPHPQDNDYNNDHLPLPFEWNDRGSDDADRKATLPMGDPMSVSSHELMDSRNHNLSNGIARKADRRRHNSFSGEIEELTSRLDSTLTRGSIDSPVELRVSAHASPRRQQTNRTLSDSAAMLSSSPDLSSRMPTTSGGDQQNGRPDLTAGLPPVPPPRTRVERKNKHEDNGSPPRLVSNGLPPTPKVHMGACFMKVFNGCPLRMHCCVSWVNPETRDQHILLGAEEGIYTLNLNELHETAMDQLYPRRTIWMFVVKDVLMSLSGKTVQLYRHDLIGLHASINNKHTLRFSLRMSNKIPEKLVPRKFALTTKVADTKGCMKCCVRRNPYNGYRYLCGAVPSGVFLMQWYDPLNKFMLLKHFDFCITSPLKTFEMIITPDVEYPLVCINVRREPDTPNLKLDLLNLNTSSSWLHSSELSNEVDKSATVIHRKDYMNVVSVTQLEKDTLMVCYDSIAKFVNINGKVKSSRKTCSEIKFDFQIDSVVCLTDSVLAFHKHGMQGRSFRQGDITQEITDQSRIFRLLGSDREDKVILVESRPNPTGPPLTTEEGVNLYTLAGHEATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0F7</accession>
    <name>A0A1D2N0F7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Multiple epidermal growth factor-like domains protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_07989</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000335">
        <property type="protein sequence ID" value="ODM98691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N0F7"/>
    <dbReference type="OMA" id="PVCQWCD"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000191">
        <property type="entry name" value="Multiple epidermal growth factor-like domains 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000202">
        <property type="entry name" value="Multiple epidermal growth factor-like domains 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056737">
        <property type="entry name" value="Beta-prop_ATRN-MKLN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056863">
        <property type="entry name" value="LMN_ATRN_NET-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002165">
        <property type="entry name" value="Plexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016201">
        <property type="entry name" value="PSI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF16">
        <property type="entry name" value="MULTIPLE EGF-LIKE-DOMAINS 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24981">
        <property type="entry name" value="Beta-prop_ATRN-LZTR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24973">
        <property type="entry name" value="EGF_LMN_ATRN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01437">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00423">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 13" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="12 14" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="2516"/>
            <end position="2538"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="16">
        <location>
            <begin position="66"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="17">
        <location>
            <begin position="178"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="17">
        <location>
            <begin position="1076"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="18">
        <location>
            <begin position="1150"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="18">
        <location>
            <begin position="1196"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="16">
        <location>
            <begin position="1248"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="1166"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="1218"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="1230"/>
            <end position="1244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM98691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2666" mass="295902" checksum="4CCA2BE0CE071305" modified="2016-11-30" version="1">MQNIVIGLLLVVVEYLILAVVCPVVVFTTTGASATSSTSSPPTPYWRLLTPSSNEGSEYDDLMMPCNRSRHHITNSTYGVLSDGPGNYTQDTTCEWLIEAPKGHWISLHIDEVKTECSYDYLFIWDGNSYRKDQGRLLASFSGASKPQVTLLAQSGYMLLLLFSDPNYTLDGFKAEYSISLCPLNCLGAGECVQIQNEHICKCYESRSGFACQNISSPNSTTDALEKEKTTGTENRHLISANYRNPLARVGHSAVQIENLLYIFGGYDLNDVLDDVWTYDLDNNTALQVLKKSDESIWPSARYGHSGVSYNNGFLVYGGHLQSAGITDDLIYFDVKTKEWTTMSTSNRLPALAYHTMTKAGSYMYIYGGGTRWGGFSHTLYRFHESQPLEWELIISSCCGKPEDRAVLGHSMTFWPGKNALVLYGGVGAADVGRFSKLSSSIYLYLIEKNVWLRIDNKRNAGLQFSLTPERAFHTAHIVNHYLTILGGYSHQHNRDETCYATFVLVYSLECHTFLPQKASMKLEEGIFGHKSFVFSKNSTEEFVIVGGYRGYLNQQVQKVPLPFSNRTSESCADHDRWQWQCASDPKCGWCPSNNRCFEKTSGANCTSNLITLQCPGICSLLSSCRACVIPGMHCAWCDYSEQCLKLEDLHHTCVPKTSTNKSIKHHSSECFDKSYRLGLTQIEYRHPIDFKNPDNVRITNSSVLILSRDYAGGNGNNREVISELRGVVEVFTYTAKKLEICTSQAEVNLSLSSQEETYNTSFNWTDHHHCYNLTMKSGKPVILLPDLRLQLTLSAKSFGPEVKQEKSGRGLINAFFNCRVIIQPKHTGSPNFRVLKKENLRPYEQPENCSIHSTCLACMVNALCAWETETSRCINRTADISKEVGVYPVVLTPDECPLCTDKKFCEECTRRPVGGVDCEWDEAESNCNRKGRHDNNTKKSVGECSLECHLRSNCSSCLSSTSPGCVWCEQQQECFVFSVYTSLYQFGKCYQWADKLEQCSRCGNQLKCEPCVEQMGCGWIYDEQGGVCTEGDYSGPYSLPEIDGVNLEFNEDNELRELIPKTYTNKTWTYSICPDVDECVLNLHDCNHPNATCVNTPGSYKCICNRGYTGDGRSCEKTCLHPCKNGFCSADFLCECDIGWTGVDCSVDCGCNYHSYCESGRCDQCDHSTTGKNCEDCLEGTYGNATLIEVGCRQCECNGHGDVSKGLCDRVTGKCYCLNNTDGDHCEGCLPGYFGDPSRGHPCYRKCGGRVVLNGTQGYFGFYPEKFNVYSPKLSSRKYGLKETEHMSSNVPVITHCLWLIRATPEESNDQPDEIANLIDPTYEELVIEIEKEYAISCRRNGLQIFSSWAGSRYHAPLIATVCSDDYDSPPFRGNVVISLPGRNAAVLFQFAQMGMVKFAFNASYRLVRKRTITPPSTPVSDSSVKISKLYDGRSVLRRFGHSLHLESKNMWIFGGYSLSHGPLNDIRHYDRDSGMWVPLTITVTQGEEAVPPARYFHGGTLTPPSSIMIHGGISSNITFLSDTWKFDTRSSRWTKLCDGLLDSPKLAGHTLTVKPETDGEGFIVIMIGGFNSFNGFSDKVYILSSTSSECWTALETLGSGPVGIYGHSAVYHHHSDTIYVFGGMIYESHQVIMSNRLYSFHIPKKRWSVLPYGDDNYWPSPLTFPPRKYLHSAVSTDSYMLIIGGYGTTKTVSMIAYVYSCNSWQALDQIEFQDQLNLVATASSIYNHQVLTMGGLKVSGGASTESVYQLLLPEDILCSVAGNNSDRCKAMMFCSLCSSNNDQKEQCYRSELDMPTKCSSGATNIRFWAGKACSTISFHEDKCERLRSCGECLAVWPTHPNSSHDLQQGKQCYYGVNARAVHGAPPTLIASQCEKCGASGCIWSRQIIRNPQRGIEVRSMSVYDWSCLPKFILNSTSISVSSSPPAPCTIPCSELRTCQECLKSAGGEGGYSSCNWSTFLNKCLSPAHVPMLCFGGVCGTVLQSDPAICPLGCGVLRSCSSCLQNPLCGWCAAEDKNGEGVCVSAEKVVGEGFSCGAGFNWSYAVCPKENECTNLHHDCDAISEVCINLDEGYRCQCKEGYNRTETGCIPICVPQCVHGKCAAPNKCLCDFGFVGNNCNDKCNCNGHSNCLEDDLDNCINCVNNTQGPNCAKCKAFFVGDPTNNGECISCHDYCNSHTSICLSEENYNQFCNNTVATNFDPQKLREEILASGVLSGPTSVARCCGCSNKTSGSTCEGCLQGHFRAYSESSQPCRKCECHGHSDTCDAKTGLNCQCGNNTDSEECPSGTIKQSPHHQCWKMQCCFSPETKPCSLSPEPLLSGRTAFFAVQPKFMNVNIRIWLDVTIGAINVYLASRDDTFLVHWDNQSNLHRVEFDVKYGLVGVRNDIMRGQPPRNNPFVVSQDEGVSDESQTLEALSIENMSEFGPTSQPLTTVLPGMGHKLVQIEAAGFASYHTVTDPKAVLLVKNLRNRLVVTLPQESHDLRTTRFYLILEGLGDKSHGSIFFRQDQQHIDLFVFFSVFFSSFFIFLSLCGVLYKFKQSIDIRRARQRHVDEMLSMAKRPFAVTTVILEPDPNSHLYEAYTQCRKVCRKGCICLRPIAAEFTSDHANGGSGPNNSTNSAVCTMLVTTAGGPSAPVRLCLASVLVSLRNYPIHNTRRRRMQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0M5</accession>
    <name>A0A1D2N0M5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000322">
        <property type="protein sequence ID" value="ODM98788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0M5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="242" mass="27006" checksum="E9089F8BA92DAF44" modified="2016-11-30" version="1">MGAETFFEQKDVNLSKLPQAEAYDDKYNRVTFLREKGTGLVALLATCVVGLVVSVLMPIGVFWKSWKSLRTAMGLLLAICVSQIIIASIYLSNQVIVVSLIAIPFRIYEIHLIHSYIRYYKEKKKRALLGSADAGLYSPTDSQAHLGVLSVQSMDNNLDRPQGQSEVTLDLNDGDMNISDGASNELGQDIDRSVTELANKRRGKKKRDNAVTTSISRWRRKARKGRALSNVQSESLRDVDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0R5</accession>
    <name>A0A1D2N0R5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000312">
        <property type="protein sequence ID" value="ODM98897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0R5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="139" mass="14871" checksum="39854486EF05293C" modified="2016-11-30" version="1">MSGKGNTPSNLNLASALYYENYAYAPSLASIPAQAQDEGINRNMSTKKVCAKSMKSRSRYGKYTAVATSAPGSSSSSSPPPFSVARRQAIRRKFLPPVPLKSAELVLIHGQQQATKTSNESGPGQQAAKPHVEVRDSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N197</accession>
    <name>A0A1D2N197_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000302">
        <property type="protein sequence ID" value="ODM99063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N197"/>
    <dbReference type="OrthoDB" id="10553768at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="27122" checksum="7ED80C6C8090C06F" modified="2016-11-30" version="1">MSEVALPPTQKEHHPRVNTLDKQTQTKSQDVVSEISGLQPVGEEKVGFFVKLKGIMKCRCCCSLRSAVYFGSSILIFVATMAFGMFLMQSTVFLYLHFSGKADQQSSLTLISFVELLVGASFLPLGCLIFKGVEKESLRLIKWPVVVLFILKLVDLALKLYRNTQTKRKKFDWEARLYEGFDVIGFTLYFLVLFFYGKKLAKEMRLLDRTDYFQSPAEQNLNLKGSKYLNKSEFESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2H7</accession>
    <name>A0A1D2N2H7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000279">
        <property type="protein sequence ID" value="ODM99472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2H7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="25028" checksum="520EAB3432C66BA4" modified="2016-11-30" version="1">MFPRLGISHSQTRTLLHPRNPQYLHFHCQHPSLRKTKLKIAESWTFSVLSSSDSESDHTICFLVILFLLGGLTSSLSLLLVSSSSELFRFETLDESNSIEDSPIKSIVALADVRFQESSNFSEETELLSCLAEEVDSSEGLEKNEWGVVDVAGGDCTKSSSSSSSNSKPMLKLATFCEVTEDTALVSGEEAGGVETFLKNPDVLGCDDDVWTKGALSSESKVRIITESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Q1</accession>
    <name>A0A1D2N3Q1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000248">
        <property type="protein sequence ID" value="ODM99898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Q1"/>
    <dbReference type="STRING" id="48709.A0A1D2N3Q1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="183" mass="20231" checksum="91B90F995473E11F" modified="2016-11-30" version="1" fragment="single">MKEKMGFHSKTKRSLLSLMPSSTSTLSPGNRLLRQRCTISTTCGGGGSNDSDDDARFHRTWQRCWWLSNQIVFVTLLLLVTMSPVGVVRGEITCPPYQEIPYCSCFVLDDQLHIQCSGSDIPALKKSLQVLNGPVKSYSVYDLDARATVLPDGVTDNVTSPVFHVQAMDFCGFDIKTLALACY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N593</accession>
    <name>A0A1D2N593_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_06430</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000221">
        <property type="protein sequence ID" value="ODN00235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N593"/>
    <dbReference type="STRING" id="48709.A0A1D2N593"/>
    <dbReference type="OMA" id="LWHYPFN"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000004">
        <property type="entry name" value="Glycoprotein 3-alpha-L-fucosyltransferase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031481">
        <property type="entry name" value="Glyco_tran_10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17039">
        <property type="entry name" value="Glyco_tran_10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="66"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="214"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN00235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="416" mass="49318" checksum="4DCE433ADB9A750F" modified="2016-11-30" version="1">MGLKTQHCRLTCGLVITLIFFATYTLLQNSGPRLRDYYRRKNILPIVRLADYDTDDAQEAKRLYPRQILFWTSLIKEEGEGLRAFCFKSKHLQNCPYKCDFTTDRSYFEIADAVVFDCRNLKIKKKTIWDWLWDEHDDIPEFRMHRQFWVFHMMEAPVHTWINLKPFEGLFNWTMTYRRDSDVYIPYGRLKTKQTEVGKYGTVDLNLTHSIHGRKLAAWVVSNCRFQPSGREQYAHELQKYIPVDIYGQCGSLNCTSYNGICEDPVTCYKAIGPKYKFYLAFENSLCVDYITEKFYNALRFGMVPVVFGYGDYSRVAPKSSYIEARSFESPKQLAEYLLFLHTHPEEYLKYFEWRKSYLVHDVYYFEDAWCSLCEKLWKTPANASYQQSASASDLERWWYHTTNEVSSKPACQHSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N604</accession>
    <name>A0A1D2N604_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="4">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000190">
        <property type="protein sequence ID" value="ODN00703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N604"/>
    <dbReference type="STRING" id="48709.A0A1D2N604"/>
    <dbReference type="OMA" id="NHVFEQV"/>
    <dbReference type="OrthoDB" id="3633556at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF32">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="196"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="810" mass="89483" checksum="5EE3A47F15BB2C13" modified="2016-11-30" version="1">MPSISQIEEGLPVLTGFSLQHKKNGENELFQNGISNGIHKKHHAIEKFESENNIILSERNGNHYTNGNGVAYSNGNGAAVDLANGNGYHDETDRAQVLKSESLTNGMANGIHISPAEKTSINASVPATAKTPSVNADPEDPSISWKKDGVIYNKGPDQILPSEALYTWHSDGAVRISRLGSGEMADRTPMSVPSLLQRAAQRAPERMALAVKRNGEWQKWTYKQYLRDVRTAAKGFIALGLEKYHSVGILGFNSPEWFISDLAAIFAGGFAAGIYTTNSPEACAFVAKDSKANILIVEDEKQLEKMLRYRNELPYLKAIIQYTGEPKEPGVYSWSKLMMLGSQQPDDVLEDRLRHIAINQCCTLIYTSGTTGNPKGVMLSHDNMTWLAHINGRTCNFRDFVEEYISFLPLSHVAAQMADVYCPLTCSASVYFADKNALKGSLIDTMREIKPTKFLAVPRVWEKMYEKMQDIGRSTTGVKKMIATWAKAKGLDYNIKRMNGVENPETLGFKIANKLILSKIRDALGLTRCDLHLSGAAPINPEILKYFMSLNIVVTEVYGMSECSGPHAMAVESAFRVGSVGKTLMGVTTRLDKPDADGNGEICMGGRHVQMGYLNQPEKTQGAIDENGWLHSEDIGRVDDDGFLFITGRIKELLITAGGENVAPVPIEDNVKTALPILSQAMLLGDKLKFLSILLTLKTEVDKETQEPLDTLLPFTRDWIQKNGDCAVVTVQDALKEIYEKKNQKLISAIQAGIDAANKKAVSQAQKVQKWHFLPKDFSIPGGEFGPTLKLKRQTVVQKYQETIDELYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Y9</accession>
    <name>A0A1D2N6Y9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_05652</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 20">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000175">
        <property type="protein sequence ID" value="ODN01033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Y9"/>
    <dbReference type="STRING" id="48709.A0A1D2N6Y9"/>
    <dbReference type="OMA" id="KACMSDI"/>
    <dbReference type="OrthoDB" id="3256376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902533">
        <property type="term" value="P:positive regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000190">
        <property type="entry name" value="Proto-oncogene tyrosine-protein kinase receptor Ret"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000678">
        <property type="entry name" value="Tyrosine kinase receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF621">
        <property type="entry name" value="TYROSINE KINASE RECEPTOR CAD96CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="380"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="120"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN01033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="683" mass="75813" checksum="954BC6535310F75E" modified="2016-11-30" version="1" fragment="single">CNADFDPPFNPITFRVNNNFWRIHEDEAVGTRVANILRNRENGAANVTFKVERSHFSGEDFSDHFRVDAKSGGSANIILQKSFQGFGSREFLVSVVGYVGSSTRTTRVDIRVQILASGNSEDKLPIPPKDTQSLLPPPGAITPSPPPDVIDNNFPENPSATSSSPSSTSNVPKTTSGADSTKPQDGLSPDTPIFQPHVPTTSHNSSESDQTSPSTYPPPTYNVPTKNPHLTEPLDHDKKDYPEIPSNDIGETAAANSAKGNSSNKTVGVGVPQDENGDGNMALFTTIPIVAILAIILITASTLYLVNKRNKVKKRPVKEIRKESAVTINSNNTMSGEGEPPTALQQWVGKRAQSNRYESWAPDAVPTQAIDRWEFPRHHLQIGGILGEGCFGQVWRCEALNIDGKEGTTTVAVKTLKESAGDRERQDLLSELSVMKMLDPHPNVVRLLGCCTDKDPIFVIMEYVALGKLQSYLRSSRASHYYGNLHGDSTSLSSKDLTSFAYQVARGMEYLSSKGIIHRDLAARNILIDKERICKVADFGFARDIVDNHVYERKSDGRLPIRWMAPEALYDNLFTTKTDVWSLGVLMWEIVTLGSTPYPGMAAAEVMRKVRDGYRLEKPEHCRRELYNIMFYCWAHNPVDRPSFSDLVNFLSHLLFSETDYIELDRFPDHDYYNMASLSGEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8F1</accession>
    <name>A0A1D2N8F1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein hunchback</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_05162</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Gap class segmentation protein that controls development of head structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the hunchback C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000148">
        <property type="protein sequence ID" value="ODN01524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8F1"/>
    <dbReference type="STRING" id="48709.A0A1D2N8F1"/>
    <dbReference type="OMA" id="EENHMAS"/>
    <dbReference type="OrthoDB" id="10015593at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040034">
        <property type="term" value="P:regulation of development, heterochronic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035282">
        <property type="term" value="P:segmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001301">
        <property type="entry name" value="Blast:Protein hunchback"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001482">
        <property type="entry name" value="Hunchback"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0302">Gap protein</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="15">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="15">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="15">
        <location>
            <begin position="675"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="101"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="375"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN01524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="728" mass="81856" checksum="A0D89CA47B016FAD" modified="2016-11-30" version="1">MLVERSRSVGALAPSATSPVARHHLPADLSPRSSNSSLLSSNESLLNTSLSVPSPAKESGNSPGGFSALQRLQYALESNTLFSTYFHETDNEHLEQQISKTYPNLSPNGSLINSSNTRDDSDETAEEIQEDHLDEHHAPSPRNGSEMGVVSSPTGSPNSTGNGNLANTIFQCPLCAVVCSSRHDFNEHLVTHSQQHACPKCDFITNTEEALRDHVHEAHGADDVVDMLSDDEMKTPKTNAQGKLKTFKCKHCEHRAVTKKEFWDHTKSHIRQEKMLHCPKCPFVTEYKHHLEYHLRNHFNSKPYQCNKCSYSCVNKSMLNSHLKSHSNVYQYRCSDCSYATKYCHSLKLHLRKYNHNPAMVLNPDGTPNPLPIIDVYGTRRGPKIKRTDPNLEGMATTPVASSPTKPKAQRKPSSTPIKKEKTEKQRQLDARDLSPKLASSPRCVSSMPNQSITPPLKRMRTESGDSESDMRISSHPLMQNTKVPQLPQAPISPSSIALILQQNGLDGRKEMAAFPHPSPNPLEFYNAALNQYLLNPMFHMAATSPLNELAQQMANDQQTKLLAQLLQSRMMQPQQMQQQQLNINMANDLRANKHANLAMNGGALDLSKNEDSAMHDDLKKRKRKGKALRYERRFSDDEDEEEALDFSNNNNNAFQVNRERKGYDGPTDLSVPNYMCKYCEITFPDRELFAMHMNFHSGDMDPFLCRSCGKKSKDKIAFYKHVATDPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8U4</accession>
    <name>A0A1D2N8U4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000143">
        <property type="protein sequence ID" value="ODN01690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8U4"/>
    <dbReference type="OrthoDB" id="10553377at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905225" evidence="2">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="14923" checksum="828DF311F95DF459" modified="2016-11-30" version="1">MKATTVICIVLGVWVCGAYCSTQLEEDQSVVELAPEYNSAGHRAKRSPLDPIVAPLLIGKSFLYGALVGPKLFKPYYRPYYHHYTTQFTTTPRFITGIMVMVGLMGVTMGVFTDMDMAVKPVPNHIMLSNFINAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N933</accession>
    <name>A0A1D2N933_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000139">
        <property type="protein sequence ID" value="ODN01773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N933"/>
    <dbReference type="OMA" id="DMTTDPE"/>
    <dbReference type="OrthoDB" id="10462260at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="23655" checksum="F70EF324E546DF59" modified="2016-11-30" version="1">MELLNDDPWERKRTVATLAILDILLAFFLIGYAGARLLRYNFTDQTVVYVLYSEESVFLSMVYWLTVFTFLSLQVVIAFFLLTATNDMTTDPETMIDKCYWWKILSQVFFFCLTMDLLFILYDNLINGRPLKDVRAALDTLEVIFRGYGIFFIGKFMSDLKGLFHSPIVQYDKNGTPIPPTPPIKAKRSIPLDDRYSDRENYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9G1</accession>
    <name>A0A1D2N9G1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anosmin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000135">
        <property type="protein sequence ID" value="ODN01881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9G1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00003">
        <property type="entry name" value="4DISULPHCORE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00217">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905257" evidence="1">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="35"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="8901" checksum="7AA3244DC3F94571" modified="2016-11-30" version="1">MNRAVAIGVGLVLVVCMFSMVDSNIQNKTCSAAIASTKSGTCPEPNPQIRCFHCYDQCRGDAECTDNKKCCPQPGCGNNCNAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9I3</accession>
    <name>A0A1D2N9I3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">THD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tumor necrosis factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000135">
        <property type="protein sequence ID" value="ODN01901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9I3"/>
    <dbReference type="OrthoDB" id="5947373at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005164">
        <property type="term" value="F:tumor necrosis factor receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006955">
        <property type="term" value="P:immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006052">
        <property type="entry name" value="TNF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051748">
        <property type="entry name" value="TNF_Ligand_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008983">
        <property type="entry name" value="Tumour_necrosis_fac-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15151:SF24">
        <property type="entry name" value="A PROLIFERATION-INDUCING LIGAND-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15151">
        <property type="entry name" value="PROTEIN EIGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00229">
        <property type="entry name" value="TNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49842">
        <property type="entry name" value="TNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50049">
        <property type="entry name" value="THD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="THD" evidence="8">
        <location>
            <begin position="498"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="654" mass="73512" checksum="539522F77440B1F3" modified="2016-11-30" version="1">MHVPLDLVHETHMHKSKGTIITKDTKTTGSTTSDTGESQQNEAAPVAGRPSAHLRPLSILSSLSFLKLRSSNAWTRTRQRANGFQNELTEDEEVVVHFKRPVDCTSSPIEKTKRTELNSNQKVPCNIQNAHQVKDCYANLLNSLPNVIHNESSNKLYSKKVEAKAQHSRSGDNQVHLNKVSHIYGSVENSVGFTGSFALHNSGRMCDQGRDLMTKQQSVSLHNLDDELNKPPRNQACTAGVNHKSWWRVEGGSYLEVRASHLLKLVCLLMVLTFVAAFTFHSRIRQLEAQRTELIQELSGVKMHLEILIDRMDTVVSLAIPTKSSRAASFHSEQLEGDDSSMDAKEESDQILEKVGARNGKRVLVKRSAAAGRTTKDLQFPSSSFSFNTLNNGSAAFDNLDDTWSPGVTPKDEKTKSPKGNLRNKRLSRKVRKLVRKELKDFKAAQRIKLNTLKRKLSESRLQKRLLKLSCCIENTSSSHNLSKYPGDAEIRQKTGVRAAYLQIDGTSVNIKKPKLELIGPWYLPESGDDIGFNDLWYNNLALDSNGTTIIFEESGLYMIYSQVFYQLQRSPKSHGSPLGYRIYLKKSQNKRAIPIAECVPSYPQTVYQTCFTQVTWFVEAQDEIYLEHFTDSLPMIDALRSGQTFLGIVQLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAE2</accession>
    <name>A0A1D2NAE2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAE2"/>
    <dbReference type="OMA" id="AECINEP"/>
    <dbReference type="OrthoDB" id="6586554at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="703" mass="78433" checksum="43710C5D1B21A05D" modified="2016-11-30" version="1">MGNFRQPNAGSQHSSEGGSPSPRGNSTSTSGKKPTNKASVGWTNLRKGRRKKPVPMVELSSDTDFEEMPVTQTPKVVVIERDADRPIRQDKNEVEVVLFNAISDTEEESINVQKTTGKEKKATRIASRRNNNNVEPVTPIVINGSNMKTKNHQSNSNAEESSQTMNGGRNGSEWGRDSDEDSYVTLFIPKDSNIETAQNNKKKRKRDDDEDASRSSTDFEVVAECINEPQKPTSSSRVNKNSSSSENENADSDSSEESSSQELITTRSRSSSRKRKTLPAKRSNAKRSRFEAEKKKTKVVKKKSTKRATRQTSRGSKIVESETDEDKDCSKNSSRHSSSESDEEISSSRKSLCTRRSTRQSIPKKLDKKEKIRQDAFEKLRKKRETQAKRPKRKSPVREVVSSSEEEDSDSDGNYSPVPIVSNSSEEGTDFDGDGSTPSSSSVTSAGETDEEPDLEIGGSEGEKDLPNSEEASEGNGDTYTEVASCSSSSDEEPPSDGQNDTRCILCKNLKTAAANIEGRAKRNNPRDWCKCGECKIFARSVGDYDLVCCREIKAVKDFLNEELEDKNVCITNHPRFEADVLKNEGYARSISKHKEPYSYWQRSYWQEHDDRHSSRRVGVLSATTATEGFKRAPKVEKTWKSFSSYKYWIFDKLGVSDSRQMVIPACVKAKVFDKFGTQSNFVPFHPPTVCPCKKHCGPASSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCT0</accession>
    <name>A0A1D2NCT0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000088">
        <property type="protein sequence ID" value="ODN03067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCT0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905383" evidence="1">
        <location>
            <begin position="21"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="67" mass="7336" checksum="3FEA47E548C1E758" modified="2016-11-30" version="1">MQKFTIVILVVASFAAYSSAAVRPQSKLYFSTSLTPPLHPLTLLKRPVTPLQLPPATQQPPPPHKCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCY0</accession>
    <name>A0A1D2NCY0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NCY0"/>
    <dbReference type="OMA" id="FKADNRR"/>
    <dbReference type="OrthoDB" id="265776at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000018">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057368">
        <property type="entry name" value="USP32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF76">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25265">
        <property type="entry name" value="USP32_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="287"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="7">
        <location>
            <begin position="396"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="6">
        <location>
            <begin position="835"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="516"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1132"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="538"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="570"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1132"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1575" mass="177620" checksum="AFD1B4F43E993A3C" modified="2016-11-30" version="1">MFKSIISSISGYLGTKESKAVCITYEDARSRITDAEYRRLYDAFKRVVTQNSHMSKQAFAREVLGDLFPSEIAGDIYIACGGTSKGIQFKDLVTALVLLTKGTPEEKIRFIFSFYCNDQNIIVKDEFIRFIQEVEGCNVPDSLYRLFMHNTITEYEPFRRWLLENPNVTSVSCWLIGKDNQRTSNPGYGYSHFTLSDDHETPTFYQTLAGVTHLEEEDIIELEKRYWQLHSYSRSGKMDIATLLPLVSPPLPDSIFQGFFDAFDENRDGHIDFKEMACGISAAARGPPIERQKFCFKIFDLDKDGLLSLEEVDKMVRVLKSVLLETVSDTNAKDDILAAVLKDDCLYVNEIKNTIVSQSGMTLEEYLVWSLSNPLPEQFLTLIYQVCQIVFGLKPLDPAEEFDVVMSWLSREEKRGFQAGQIWYVISMDWWNAWVQYANPNPAVMSNSDSGLSSISGSIGGGYSNGTVSCDNVGANDNRVRSGSARTCWSLRKSTVDNTVASDNSQNVVVTSINTIDHEENDSADRPSSVALNHHSKTSSSSLSLATLDSSSSTPSPVNSPGSVRRGLTGSINGSSASSYTNGGRKRRPGAIDSFHLLISPPSTLSKTPSLTGEGGRLRNDIVEGRDFKILPQTLWNALQQWYGAGVALPRQVIETEKKLELELYPLTILLYRHQQPTNAVQKSMPPASGTPWAGMAGMYGATALSTTISFVQNSGMNPPKRILTFTASFSRKTRIIQVWNFICQKLRLVHQDTRLDLLHPDDQTFLFVLEEEEQTLEEAGIVDNSHILIETRNKDQTWPEEIATVVSTNSGSINNEQQRVRRAMSVSKSEKGVTGLNNLGNTCFMNAALQCVSNTKPLTLYFMRKMYMHEINRTNPLGMKGHIAKQYGDLVIQMWKGQCKTIAPFNLRLTIGKYSPRFSGFQQNDSQELLAFLLDGLHEDLNRVAEKPYVELKDSNNRPDIVCAQEAWENHLLRNKSIIVDLFHGQLKSAVRCRACNTESVRFDPFNYLTLPLPMESYLLCDFIVVRQDGKTPTRYGILAGTEDRVTEAKQRLCDLVNLRDPSMWKLVPDNLLLAESRQSRVTNVFQDGQRVKGCFVSKPVYAYEVCTPLIDEQGRSERPEQDEQIKRILTSSKNQTSQSSGATLRPSSADSGAGPTHSRQSSYSSSGSGNGNTLPLLNEGGHLKDHFLIAVHRKVMRQESYFLASQKSHPILFGTPIVIPVSDSMTHLELYKRVWGMVARLLSPLPPVEGPNIYNHAQDCDDSLGYEYPFVLRIISREAEWKCGLCCWWNFCRGCTIMCSENQTLEKLNSATICIAIDWDPTALHLRYQTTQELETVEDTSVLESTKKLSESVPLATCLDSFTKEEELSEDEKYLCSKCGSHQLATKKLQIWRLPPVLIVHLKRFQPVQGRWIKSHKVVNFPFKDFYPNKYLAEVPHRTSEAAENSEKSPMIDEDLFPLQDFHQHRLSEGQNPFDLKYKLYAIVCHSGIMGGGHYISYAKGTNDKWYCFNDSSCKEVQEDQIETSTAYMLFYEREGLDYEAYLPRIDPKAQPVVTDDEMEAEENDLKKLCCMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDF9</accession>
    <name>A0A1D2NDF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDF9"/>
    <dbReference type="STRING" id="48709.A0A1D2NDF9"/>
    <dbReference type="OrthoDB" id="14612at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-CoA carboxylase BT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Acetyl-CoA carboxylase central" evidence="1">
        <location>
            <begin position="104"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="289" mass="32691" checksum="57FA7438C3D1641B" modified="2016-11-30" version="1">MSDGGLLVSTDMQSFNTYMKEEVDRYRVVIGNQTCVFEKGERSHSPQIPIRWKLWDIWLKMEVIAGAVLDAGALIARLELDDPSKVTTPDFHWEVPTEPVFQYEKAKEIIEKFMKALRDPTLPLLELQEVISSISGRIPASVEKKIRKLMTLYMPATLLQFWLSSQVSKLPVDCSTRSALQDGIRGRMKSAVQELLRIYLGVETQFQHGHYDKCVQALRDKHKDDMQAVTSCIFSHYQVAKKNIVVTMLIDHVWGNEPGLTDELAAILKSSHSSTAQKTLGLPSALAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEZ3</accession>
    <name>A0A1D2NEZ3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">acid phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02879</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000063">
        <property type="protein sequence ID" value="ODN03821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEZ3"/>
    <dbReference type="STRING" id="48709.A0A1D2NEZ3"/>
    <dbReference type="OMA" id="YDFENIW"/>
    <dbReference type="OrthoDB" id="10257284at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF211">
        <property type="entry name" value="PROSTATIC ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905468" description="acid phosphatase" evidence="8">
        <location>
            <begin position="32"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="472" mass="54039" checksum="E0F2BC65CB3BB534" modified="2016-11-30" version="1">MTLSIFSRMYLFRRLFCILFLLSSTLRPISSCIPGKSGKGNELTADAFSAGYYCTNGSSGNNTDGYCGLTKLLVVQVIFRHGDRTLIFHYPKDPNQNSSGVLHLKRKGILTNKGKVQAYELGQYLHSRYRKFLKGTLIPEEVLVQSSEISRAIMTAQMCLAGLFPPCEAHHHQPGCEGKWDPSIKWQPVPVYQIPRKLDNKILFQRDTCPAYTSEFKRVLECPLIEEFKKSHQETFQYIKEHTGMDEVNIENVGQVHDTLFIQSLYNISLPNWTEKVYPEPMKTMSDLGFQILSANREMMKFNGGPLLKEVIENMESTVEFLKCPKKQKEKKRVKKVYLYSGHDTTVAAFLATLSVFDTHQPPYTSAVIVELHQMQEKGSGSKKHLVKVFYRNSTAVAPREMIIPDCGNPCHLDKLKEVVRDLLLEDWGAECNQTFFSYFLDWLSRPLTYILNLLAEAFADTLKRLRCCLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFE3</accession>
    <name>A0A1D2NFE3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Myosin light chain kinase, smooth muscle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFE3"/>
    <dbReference type="STRING" id="48709.A0A1D2NFE3"/>
    <dbReference type="OMA" id="WVRSINA"/>
    <dbReference type="OrthoDB" id="10260894at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342:SF20">
        <property type="entry name" value="MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="57"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="300" mass="34477" checksum="347D279E8E6205E1" modified="2016-11-30" version="1">MRELNAVGFDLESNVKPKKNLGFLEFYPCLYLNVSDCQPSFPYRDVSTRLDNFRTAYDVLDEIGRGKFGLVYRCKDRKTGLMLAAKVVTVNKKDEKRDVRREVDIMRQLRHPRVIQIYDCIDDLIHSEMCLILEMVSGGELFDRVIEDEFILTEKACAVFVRQICEGIEYIHSKNILHLDMKPENVMCTSKTGNRIKIIDFGLARCYDPTKKLQVLFGTPEFVAPEVVNFEDISYATDMWSIGVITYVLLSGLSPFMGDSDVETMANVTIAKYDFDDESFDDISSDAKEFITKLLVKDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFP0</accession>
    <name>A0A1D2NFP0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Breast cancer type 2 susceptibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFP0"/>
    <dbReference type="STRING" id="48709.A0A1D2NFP0"/>
    <dbReference type="OrthoDB" id="21095at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015525">
        <property type="entry name" value="BRCA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015188">
        <property type="entry name" value="BRCA2_OB_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002093">
        <property type="entry name" value="BRCA2_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11289:SF0">
        <property type="entry name" value="BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11289">
        <property type="entry name" value="BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09104">
        <property type="entry name" value="BRCA-2_OB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00634">
        <property type="entry name" value="BRCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50138">
        <property type="entry name" value="BRCA2_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCA2 OB3" evidence="5">
        <location>
            <begin position="888"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1032"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1059"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1086" mass="118451" checksum="90F0C65977747E73" modified="2016-11-30" version="1">MSETGDKGNNKPPDDGAGHKGSDEGRKLVDSSSGDGDLQNTGRRKSKVFVISDKAKEAARRKLKELQEAEKNKLACSSSSLLKDPASVDVTTISEPPTVSFPTASERNIVVSDDTLEATKAKFINDNLENIVESWDINDDFSTAGDTLVISGDALKSLNVQLIDETLLDFAESCCVMSDSSTGVEMKQDLVISEDAVKAGKPKLFQDHVKNFAEISNISSGFSTASGKRLVVSDEAVKAAKTKLTDETVDLPSTKTEPGFSTAGGRKIVVSEVALEAAKAKFNEENLKKSDETPIPVPVCSTEESIAETLASMKFELSDDDLVDATETDCIIPDFSTGGGIDVVILDDVAKPKVPPDNFENVKKASNVVTGFSTASGKKLFVSDKAVEAAKAKLTDDDPDLAKTDPGFSTAVRKIAVEDALKAAKAKLTDDDLNLAKTVSGFSTASGIKIAVSEDALEAAKAKLTEDDRELAKTVLGFSTAGGRKIAVSEDALEAAKAKHIVDDFDITDITPGILTIGSKNDVSNDSRKNEKTQLREESKDDAAEIRLEASMTKPGRVILESEEDIDNSMVFEEQNEIRVVMTERNLKLEESYCEADVSIEKESPDDVASEINESTRILLEDIDNSDDEWTSSEDPGLKTKAKCPLASVVPGGEIIPSLKVAVTRVYPIMYCALGTDGKSNFMTEKAFARHQQEKSQKQSALREELLPGLEAEIRNRFVKKEKINPKDVTPRALRRMTAEEILHILNNLEDDAQTVNFVMGHINLTVKKDLEIAKADLLEKIRRAIGDELEVKLKAALPAGKSPSRVLKIRVMDVESFKKKDSSIHGTITIWNPQEEAIANIGEGKVYEFQALKPGAYHDGQEVRLSTTKTTRISPVADVLLDEAFKRKLSTLDEVLKDGFLPPFGEFDAIGVIKEVEAFKEHNGQIVHLVDENGHVLKIKFWKSLDDSDLQDVIKVGNIVGCLNLQWRITSVENKMAFSQEFSVFHTTPKVEHLQNGFGRLNAAMQEIKQFLGTERQSSGGTKSISLPAEKVESAGVTTRNSAKRRYLDRFEEPSELPALPVASPSKRGRVSKGFVTPRRITPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGS8</accession>
    <name>A0A1D2NGS8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tudor domain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGS8"/>
    <dbReference type="STRING" id="48709.A0A1D2NGS8"/>
    <dbReference type="OMA" id="DYRQSEN"/>
    <dbReference type="OrthoDB" id="10034606at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050621">
        <property type="entry name" value="Tudor_domain_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948:SF29">
        <property type="entry name" value="FI02030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948">
        <property type="entry name" value="TUDOR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="1">
        <location>
            <begin position="59"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="28600" checksum="7CB0C0B81774C0DA" modified="2016-11-30" version="1">MNGTSAKTIVPEDIKMKNGNGTISDNNNDLSALITAKIKDDFLDAKQGPDSGLLSKLKSNLVDVIVCNAVGPHNFCIQDYRQSENLKMLEKNMTDFYTEYAKIKPPMNHKEVKLEGFYAAKLASKGHWVRVQVVKPFSSEKPQIMVYLLDHGSFEMTDAAQLRYLRRPYVEKLPSQAYRAKLHFLGAAGNLWEPEACNRFQKDVEGKPFCAIIVEESKDDLLQGQPIIFSLVLIDTSGPQDRYVHQSYIKRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGW3</accession>
    <name>A0A1D2NGW3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGW3"/>
    <dbReference type="STRING" id="48709.A0A1D2NGW3"/>
    <dbReference type="OrthoDB" id="6359871at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000706">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="507" mass="57196" checksum="30A2DED84B2D96D1" modified="2016-11-30" version="1">MGKQTYEINTKGLCLFCFKDCLNEGIKDPPSPLSFKMLLRYLKINILNLCNFPSSFLQSMSSQEVDIDAVITTCAECLEEQKKFCRLFQQFEQIQLQLDKCVQTLYERMTDGSRNSDQVREYQTRMRTSDPTKLFEAYVAESLRKQVLQNCSLKIDSSNVQMGQPSNKDDSGNFGNICPHSNPSELQPRIHRIQYSEAPVSTSSRLEIVSTNTVAQRESRFPSISEQNGNDNTQEMQNDERVYVKVEAPTFPDREDPLSSETEPTPILPGLSSLSSPTSQFLPNFEQGRNESISINISKSSTANYTCAECGKSFSSSNGLRGHRAVHTRNKVLFGKRTGIANRRLKKCDVCGKTSIDLQRHMKTHLQPKSVLCSYCDKRLMSQHNYRLHFVAVHTMEAFSEHLPPGTTSTELENVIKAVYNSAKPVLSPDGKLGPNVECPYCSRTSDKNSALRTHLLFSHFDKVLMYFQNFPNQMNISAQEYGVVEGGEATIDSQMISHDFETDPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH73</accession>
    <name>A0A1D2NH73_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000039">
        <property type="protein sequence ID" value="ODN04613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH73"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="122" mass="14443" checksum="F5F5DF2F306E8B56" modified="2016-11-30" version="1">MYYNALKHYCHCTVCTWSHTLSKVMDQTPITFRSGGGMGYEGFVNQLYDQWLRRETWCAVTGLIPEKQRRHYPHKFYDDVQLYNSLCRGPYKARSGIRPVYFPPPRRMFPDLKNRSVLTGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHW7</accession>
    <name>A0A1D2NHW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Levanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01855</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHW7"/>
    <dbReference type="STRING" id="48709.A0A1D2NHW7"/>
    <dbReference type="OMA" id="WMGVPDG"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18622">
        <property type="entry name" value="GH32_Inu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF1">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="6">
        <location>
            <begin position="27"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="7">
        <location>
            <begin position="366"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="521"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="577" mass="64034" checksum="7EDFD28137C77F1F" modified="2016-11-30" version="1" fragment="single">NFLEVKSTKLPLLEPQCPTEQHRLRYHFTPKRNWINDPNGMVYYDGIYHLFYQYHPYSSDRGPMHWGHATSSDMLRWEEQDVALNPDEVGDCWSGSSVIDSTNTTGFQTDPNVHPLVAIYTSAGEAGQSQSIAYSNDKGATFTKYPGNPAIPNPDIQDFRDPKVSYIRGQWVMTLAVGNRIEFYGSPDLKTWTKLSEFGADPEEGSHCSSWECPDLFPLIVDVNGDGTSLVELWVLLVSIGCGGPTGGSGTQYFVGDFNGTTFTTLGTWDNKQWLDWGPDNYAAVSFSNEPNGRTILMGWMNNLKYGDNLPTVSWRGQMTIPRSLDLQVLDKDAKKYRLTSMPVAEVETLHSPTKILEIAQEFTLAVNETVVLTENSRLKTPGMELKIELEIDQNPQFSICAYNSLEEEVCFGYEDSKWFLDRSKSGNTNFHGGFAETLRAEADREVSSQNVTIRMFWDVSSVEVFVDDGLTVMTSLFYATEPLDMIRITHGSPVGSPASLKVNSVSIWGLICTFLEEDGTTESPTTVAPIETTQPGTGTSTGSSSTTESSGSKPSVLNAVFSLFLLSTSFVTQFYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIK0</accession>
    <name>A0A1D2NIK0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein RRP45A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIK0"/>
    <dbReference type="STRING" id="48709.A0A1D2NIK0"/>
    <dbReference type="OMA" id="GPQFENG"/>
    <dbReference type="OrthoDB" id="10264038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="5">
        <location>
            <begin position="31"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="190"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="35984" checksum="AD3BABDE7D89CF85" modified="2016-11-30" version="1">MRPKTIANCTRSLVKGGAKNGIRLGARGLHEFRTAKISFGNSVGSCEAVLLPGTRVFAQASAAIGEPSDSRPGEGSFTISVWVSPAATGEMVGNSEKPSAIARTLERMFKENRAVDLESLCIKFGELAWILRVDVHVIDMNGCLQDAAALAVLGALLTFQRPQAQIDINTDELVVLPLAESTPVELHLFHLPAVTSFALCDDVLLAEPCQEEEDILPGKLLVGVNDSKELCHLHLTHPIDQELLLEATKLAQVQCLERLNMLKQLVEEVKAQREIPVYKRPKGPRTAGAELKLSAIEELSTSGPEQKPSMKYLSPLISTSDVNMLEELCIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ62</accession>
    <name>A0A1D2NJ62_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calponin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ62"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ62"/>
    <dbReference type="OMA" id="GVMEISC"/>
    <dbReference type="OrthoDB" id="21595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050606">
        <property type="entry name" value="Calponin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003096">
        <property type="entry name" value="SM22_calponin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385">
        <property type="entry name" value="CALPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385:SF5">
        <property type="entry name" value="TRANSGELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00888">
        <property type="entry name" value="SM22CALPONIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="1">
        <location>
            <begin position="24"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="182" mass="20238" checksum="F677A5869C3CA03D" modified="2016-11-30" version="1">MAFHGPSYGLSRECQMKAQAKFSLERAKEAVLWVEAVLDRKLDIPNSDNGIKDQLDFAAALRDGVVLCELINLLCPNAVKKVNTSAAPFKQRENLEMFLKGCETYGLKSQDLFQVNDLYENKNLYMVVDCLFGLGGMAQKKGFDGPRLGVKVADENKRNFTAEKLAESNKIIGLQYGTLVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ86</accession>
    <name>A0A1D2NJ86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ86"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ86"/>
    <dbReference type="OMA" id="ARYTSEH"/>
    <dbReference type="OrthoDB" id="6379064at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="12145" checksum="AC658CC64355D165" modified="2016-11-30" version="1">MGGKAATNWGCTNESQTVGGNKSALLRSFIRVVNAFRQGLDTRYGERSNPSIAAVLQKQASLSKRLSQTSSIEYADNYPYEVSVPEFERLSSRSHTETAVYYPLSNPTMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKR7</accession>
    <name>A0A1D2NKR7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00974</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKR7"/>
    <dbReference type="STRING" id="48709.A0A1D2NKR7"/>
    <dbReference type="OrthoDB" id="445564at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013235">
        <property type="entry name" value="PPP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08321">
        <property type="entry name" value="PPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPP" evidence="6">
        <location>
            <begin position="3"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="10703" checksum="765DE6659ADA7E10" modified="2016-11-30" version="1">MSSVENSYAGPRLEDGKVTVQFMNELMEWFKNQKVLHHIERYLMSQPTLIDVTIPDDKEFTVCGDIHGQYYDPISIIFSDYGTSSLKIDRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKV5</accession>
    <name>A0A1D2NKV5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000014">
        <property type="protein sequence ID" value="ODN05871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKV5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58846" checksum="D48D47FE67772756" modified="2016-11-30" version="1">MPILYEILSRCDNKTLQNAKLTCQRWYVVINESIGVDLAIGKACYSTINPPKVPFQAVGVVEQIGVKNCYVGELNDFEGCPFQHPQTVRTIVFDGPISHFNLLTLLVPLPNLSHISFHYSALENANIEHNTLRSVSLKSLKLSSHLVNQYYGREKAESVLQNVITLLQSIQSQQLQTLILDLVYIRKYERELTKAILAVLVRHKLTLKTVQCYNVLRIQEPYPPGEENPDDDTMAQIGECPLVKEEIVCRAIHEAVNIKRICYAGLRDMESDAIWNQLIVSQKNLQEFFYMNDSRDIQSTGLPCLRMNGTTLRKILFHINAVDEMRNIIHFDCGIFKSFPHLSHLLIRGRQLLFQQRIDADANITRFAMKIPILRNVELIPNTVTVLSLRDILVDAESFSKFQACLPPHLVNLRLVDAGSVGVYGIKPETLLELLKSIQLQEIEIIRSFNKTSWEVASGKDIYEEALFYRVRCIWEFHGSRGPFGIFCFKTLPMFDYGQAENTLRANDVCEVVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL27</accession>
    <name>A0A1D2NL27_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription factor SOX-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL27"/>
    <dbReference type="STRING" id="48709.A0A1D2NL27"/>
    <dbReference type="OMA" id="PAMAHTS"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007420">
        <property type="term" value="P:brain development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01388">
        <property type="entry name" value="HMG-box_SoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000002">
        <property type="entry name" value="transcription factor Sox-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF324">
        <property type="entry name" value="SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="143"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="408" mass="43977" checksum="6D85FE71DD811E95" modified="2016-11-30" version="1" fragment="single">MIISNVSKLHGAGHGAGPASNQDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKPAMVHPNNKSKSDNPKFPYNSLPSSVIRAMDSIAARAGAPFFAHHPHHPHHHPHHHGGNAHLPSVPSLPVPLTSGGGAQANSTSPAAGGLPNFAADFSRLFPPFIPTSLSEALFSRLATARLANGGTLSSAFEEEQILNATKHQQLVEQQRGSSMSPPSVSANGHPMRNSSSSSSAYGGNGMPLTIHGLSSSSPKIKSSRSPSPSPMSNPLTPNHLESGSSPFAHYPNGSYTAAAALYSGLYPSPYLSYSSLTPFLGHPGHDAPAHGHHPDLAALFDPRVANIPKKSPVFVVHKSDRRTPSPVVSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMN6</accession>
    <name>A0A1D2NMN6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMN6"/>
    <dbReference type="OMA" id="AMMEAPI"/>
    <dbReference type="OrthoDB" id="10462010at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29270" checksum="91BB73AB9743E04E" modified="2016-11-30" version="1">MFNFLKCGTGSYHHAAMTVAIIDVIFTAILLILFVLGSSFMVAFEFVGSDKNATRVLDEITDDVFGTRQGVYNSVRQRKDIAEDMGVWLIIMFLTLVDFIISCIFLDGVKSKNPNKCQVWFNIRVVIVVVFKIVVFINVVYGTNWYRCIPDLILTIYRIVGLLIGYAFLKEIRAIYTCRNCNASNNLAARNEAINLSWRRKEVQKAMMEAPIVTVTEPQDPPLTGSAKPTPTPSPVLAPRKNSPTIQQNLGAAIVKKENKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMT9</accession>
    <name>A0A1D2NMT9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleolysin TIAR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMT9"/>
    <dbReference type="STRING" id="48709.A0A1D2NMT9"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF5">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="2"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="131" mass="14997" checksum="F08368D69C7B4500" modified="2016-11-30" version="1">MIEDCRVVRDPQTLKSKGYGFVSFVKKSAATNDRMKMKEVRRLKKNLKVKPCHSYFLLFSVDLQEAEAAIAAMNGQWLGNRSIRTNWATRKPPPPKSEGKLESMKQTNILFLNLSCFQALIEYACLTTHKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN11</accession>
    <name>A0A1D2NN11_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NN11"/>
    <dbReference type="OMA" id="CHNENSE"/>
    <dbReference type="OrthoDB" id="6621890at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="722" mass="79220" checksum="074ED69426C2ED06" modified="2016-11-30" version="1">MDPAEYTISYSTDQSQGFQTEDGVQFSSSGTCVPSTSSGQVVHVISENAQNEKQIYVIKLENLFKDGGGSDTKVGGGYVVEGAATGVGGGVRVEGSEGMMEDVFKNQEEATSSSSSEEEVDSSDDNGKDDGNGKAERDGDSDEEADPFLVVSPEAVMAMAQSVGVDLNEDIASELGCVATNKLRHAILIAMQFCHNENSEGMLAEQFSKAERQLGSPSYGHESVFREISLKYAGGVSILDDGPEIDLHTSIHQTSKNEISVDDNPPTLNVHHLRTHDSQSKSNNRSPNFKLYEEPVVMVRVSEANKNTLEEENEGGKDELPKDDANNSNAPITNINANTLTSEGGASSSGGIEAQEQTEEDCSTDDEMIEMTANEIIKEITTGIASSNGKPNTSTEERDQNDEVQLVETDDCEESEELDPDYIPYLEVLIEQVVNHSYNDEFDYKISSSFQTILNDIRENGANPILHVVCDSFRDYLRNPKVSKTTLRNILSVVDAFVSSQCQPTLSQMTDLGSVLIEIIILPPPCEVHRFLTGVFMKILRNCNELLTWTCTYVTEMLKGISEISIEQLFDPFKSTLNGALSLANGLEELKIQVAQEFGWHSCALTFSRKHCAVFEGQGYTPAENDSFLEEEILKFYHNFLNNYTSLVPASELSNVRELVTALYGEKFSSFIPIAGPILATKIPTNTSKSATTKKIKCVFRKVTYKDKELIVPYRKSVKGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0N6</accession>
    <name>A0A1D2M0N6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger and BTB domain-containing protein 38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_20155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008424">
        <property type="protein sequence ID" value="ODM86528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0N6"/>
    <dbReference type="STRING" id="48709.A0A1D2M0N6"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="128"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM86528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="190" mass="21607" checksum="73C83913AB9C067E" modified="2016-11-30" version="1" fragment="single">FRVHIKKIHPEAALGNQAGQSGTKSESKSNFTTVEYVCKHCGVQLPSQSCLSRHIKTSHKELFRSQCELCGKSYATEQILRRHKNINHTSNQVPCPYCDKTFSHKEYLHGHYKYCKLFPGRQELVGEPLEDSETSIPVGQPSQTLKLERETATNSSEQLKSERSQNVGHETELVIYPETVDGYRVHTADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M184</accession>
    <name>A0A1D2M184_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007656">
        <property type="protein sequence ID" value="ODM86681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M184"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="27102" checksum="79E53E4F0C754FE6" modified="2016-11-30" version="1">MKVFQLLGIFVVISFLVISVAGVLQPEPDDEDQTMDDFGKALPKEIPAHCAEDCKACDHDVRGSPYQGMETVSQASFKWARKQARTVSIVIFVINFIFLLGAAFYLGSSFGLSEFENQPQQPDVTPNPMLLMSLATINSLICIAFTIPQVIGAWMLFIATAKDTSPKKASMMADCHQKIQLFYLLIGFVGFGILLADVLTESNPIDVECTSIFIASGCFRLACILIVDRFVKELRNYQFMMPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1M6</accession>
    <name>A0A1D2M1M6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006935">
        <property type="protein sequence ID" value="ODM86866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1M6"/>
    <dbReference type="STRING" id="48709.A0A1D2M1M6"/>
    <dbReference type="OMA" id="FIAVMRR"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="8716" checksum="17BA4F6A4306F907" modified="2016-11-30" version="1">MDELAPELLRIAEKYDLGGLKADCVYELGDKLNLENAGELLVLAQTHNAPDLKARAMDFINLNKDKLLKSKSFQTLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Q5</accession>
    <name>A0A1D2M1Q5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein sleepless</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006840">
        <property type="protein sequence ID" value="ODM86895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Q5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00117">
        <property type="entry name" value="TFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903379" description="Protein sleepless" evidence="1">
        <location>
            <begin position="28"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17044" checksum="5C1CD6CC50BB8933" modified="2016-11-30" version="1">MRCSHLVMLIVVLPVLLSSLEIQLAQGIKCYSCGPCPGKGEERKCGAEHDACSEITRMRDSNPISISRSCSSKAIEGRVKEKGEVDCDKLRPIETVRNSTLYGKHCFCYEDLCNELIPPPTPTTPGSSASVITGFSTFLQILGASISAFLIKGTFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M219</accession>
    <name>A0A1D2M219_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006451">
        <property type="protein sequence ID" value="ODM87013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M219"/>
    <dbReference type="OrthoDB" id="6784356at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="226" mass="25281" checksum="2C1CD81181574403" modified="2016-11-30" version="1">MFSVVVFEGPKESVGTIPTKWLNQTKSECKWPVKDIPNSIKNNKDPEKSWNSYPVRVISKKPINDYRKALELEKRAEATSSLETTDTEQKKRNKKQKQPKKPSLVLVQDISSDEPKSDDSEVSLTTSMISLVAPSEDEVEDHVGAAVLLNNLASATEDTAAQSEPQNTQPTIPLSTAQDSSLTYTVLLNRQIAFEKQVLTTLSEIKADIRELLHRSSTVRQLKHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M221</accession>
    <name>A0A1D2M221_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cation channel sperm-associated protein subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_19721</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell projection</location>
            <location evidence="12">Cilium</location>
            <location evidence="12">Flagellum membrane</location>
            <topology evidence="12">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CATSPERD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006616">
        <property type="protein sequence ID" value="ODM86961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M221"/>
    <dbReference type="STRING" id="48709.A0A1D2M221"/>
    <dbReference type="OrthoDB" id="5968869at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036128">
        <property type="term" value="C:CatSper complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097228">
        <property type="term" value="C:sperm principal piece"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030317">
        <property type="term" value="P:flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048240">
        <property type="term" value="P:sperm capacitation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028751">
        <property type="entry name" value="CATSPERD/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053814">
        <property type="entry name" value="CATSPERD/E_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33722">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33722:SF4">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT EPSILON-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22850">
        <property type="entry name" value="CATSPERD-E_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="995"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="CATSPERD/E C-terminal" evidence="15">
        <location>
            <begin position="738"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM86961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1116" mass="129530" checksum="D0C0C1AACA931DAD" modified="2016-11-30" version="1">MNENLTNILTNELNFHVAVLRSEDGVGKQFPDPVNKISASTCCLKSEDCDQDDSIVAAYSFLQQRSDKENKFLYVSFDLGDTFEKRIIATQYSPVNLIKGFYKMYMRWHHYYEILTDPDEQDLKEDDELLSGLRRKPIWESSTVEEKEKLKFLEDRVPKRQARLQSGPEIKDLTPEWANEIIDKRRRAHGWKDGWNDENCDTIPECIEKFENDKAIEWLFNMSDIPIHVKTPRRNEDEPYCKDITSILVLPEKKHVMALCEIKYHRSSLDDKNFTSPSPPEVNYFALYSFPIKSNIPLVYGERVSKRIFSCRYIRKDDSNPQRLIQPELIRMPGSATIFIINCDGVKVIELLPDLGKTLFNSVFYFEYGKMNEYCKQNPTYTEPTALETTCKEKKSGTPAPPPSPSTPPSPTFLRTFRLCSLDTPPLLITDVSGTIILLTFGRFYARGVISYNREARLFVGEALSSEVSGGATLPEFGWTDKFRNLIFPTLNTNGEAILTIALLQAYSIDPAEENQFKKLYEHKHAMRLIPMPIQIHRDVKNYYEENLSLCHQAYRKNYGFERCQTNSFFIQPRKVTMDIGESKTVKVRVKDDNPLLPLWVFSSDENSVGVKAFLNRNPDQNLNQHAWVLNITAKPNAKNEEEAEALVDAFFGSDYNNLHDYSTQITLINLPTVRCHVQPSSTIQAEIGCKGKKLIAHEDSYRPQCKSFRKNFNYTLKKGNFDPDLANFWIEMDSKQNRPFLKLTDKGDLRITYDYARWGCPIEPFRNDPFIPDLKIVNETTANDTAKGKRFEGKFILVEIFGATGYSYSQKAGDTYANCKRIPQDLNELIKRWKYRHRLFEIATKRLKFPLRGSGGNENNVSGNRCFHNRAVKHHFNIWNRANYVSCETPTTVPSQMLNADALKREYQVMTTRTLADDSDTSDSFINLDDEKFLDEHDRDDNDLDYTLNRVEWKRSHQRVYVFLAIAVDGYGSLCNYATMFGVSLNTTPQIDNLLSFLIFLLFWFCWILLVVGGYYVRRRHLRISYMNQARADKLEEAAWKIVYRYEKLIHGKEMGHLMHMNTDEDDKETNRAGATYAARTAHDKRKAELRMKKTHIMAQEQARHERLQKLFQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2B9</accession>
    <name>A0A1D2M2B9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase-associated protein CTR9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006136">
        <property type="protein sequence ID" value="ODM87110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2B9"/>
    <dbReference type="STRING" id="48709.A0A1D2M2B9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="389" mass="43404" checksum="88790757A39074D8" modified="2016-11-30" version="1">MMDIDKMQPILQEGHIQGGEFSGASVWKPNEFSSTYRQPNKHSYGKCNSYCYVNRLFTLVKGITTYVKIQRMSSSEGDQFVSESNFEELVALAKCLDCVWTENFHPCDCKFRKTPEGKARCEQLRAEQEKRNATDICPRIKWASTSGSGQPSKPSEPKDSTGNAPNEPTSSRKQSSEPETSNNQNGSAERENTPRGSGEKENPNQQTEFAQPMTSTVDSQGQPLEPGANRDSLKGDAGDPETGRSSNDLTISDSANSENPDTPNSPRNSGNQGAPNSDIKTTITKLRVRMKIQHQIQLGILKTKMAQGLPRTPNLVQTLREILKTKMAQGLPRTPNLVQTLPETLKTKMTPNLEIQIHPGILILRRKVLKPSQIRRETPKMQMHQQIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M302</accession>
    <name>A0A1D2M302_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_19369</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005584">
        <property type="protein sequence ID" value="ODM87312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M302"/>
    <dbReference type="STRING" id="48709.A0A1D2M302"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="6">
        <location>
            <begin position="243"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM87312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="406" mass="45314" checksum="2BC94680059EEDCE" modified="2016-11-30" version="1">MLGGSTSHNFMMYVRGNKEDFNRWSTEDLGGDPQWNYENLLPYFKKSEDYNGNYARDPASAKYHGNGGLLNVAKYDFEPGADDFLAAALEKGYAIGDYNGATQEVFSKVDATTQDGWRESTYRAFYKDTGKPSNLCIKKYAHVIKINFQYVSSHPKAVGVTYKRQGVGPAEHLHSLNIPLVRIYLLGKESKTTDAGQGFLKSPVAQPNYVDLQLIHTAFALYHNFLKTLITNARFAFVVLGRPKSFGKLMLASSNPDDNPIIDPKFLTHPDDVEALLYGLKKFVDLYENTAALNTPLFHKPVPGCENKAFKSDDYYRCVISMFSFTFYHHVGSCALGKVVDSHLKVMGIDGLRVIDASVIPRLPNGKHAGCTIMIAEKGSDLIISNHVLVLLTRANSNFKAHFHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M363</accession>
    <name>A0A1D2M363_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nucleolar protein 11-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_19270</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005383">
        <property type="protein sequence ID" value="ODM87413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M363"/>
    <dbReference type="STRING" id="48709.A0A1D2M363"/>
    <dbReference type="OrthoDB" id="6502630at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042859">
        <property type="entry name" value="NOL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048897">
        <property type="entry name" value="Nol11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012584">
        <property type="entry name" value="NOL11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15633">
        <property type="entry name" value="NUCLEOLAR PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15633:SF2">
        <property type="entry name" value="NUCLEOLAR PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20998">
        <property type="entry name" value="Nol11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08168">
        <property type="entry name" value="NOL11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Nucleolar protein 11 N-terminal" evidence="7">
        <location>
            <begin position="15"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleolar protein 11 C-terminal" evidence="8">
        <location>
            <begin position="313"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM87413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="506" mass="56866" checksum="3D091EFD233F8C1E" modified="2016-11-30" version="1">MNLWLENLINFRLSMASLSPPFILCPLPDRKALLGIRQDSSVNKAIVTLGKNIAIRYHVLEQKQESSWTTSRYWFTSPVTYCYDFGKYGAVLNHNIIALWQEADATLSNISKIKPNGRTVVVMKNGNVAYLDDVSETKSLVKDAILSGGPSKITSCNNEIDGEGAEKVNSRCEFGSDTDKMLGSCLHKDISESFVAYFGSDGCIRKKKLMAGSNEIDRIKLANLSKYISKANPVTMCPLADNSSIAIYGSDPAEEGAVVIIYDIHYDLVATHSSSRVRITKSLLSAVVGKHQAKLDEEAYPVIWETIQQVKVFENEGQPEAVICNHVIPAALEANNSSALDWILDTFSDIPEVHVVSMVVFSLKEVKESNEVNERLNKLLLRKFDKQLLTSSLRHIPYEEVKKLLGYLNALIETNWELKIDYEDESSMKSWLKWCSALIDAHYTKFVLHSETDIIENLLQAICECTKVMEAVQEMEPFLVLTYSKTSFEPNSSSISRWRTETITFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4V3</accession>
    <name>A0A1D2M4V3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydrogenase [acceptor]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_18664</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004239">
        <property type="protein sequence ID" value="ODM88017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4V3"/>
    <dbReference type="STRING" id="48709.A0A1D2M4V3"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="900"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM88017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1129" mass="126396" checksum="502074ED8180EB36" modified="2016-11-30" version="1">MLRYFLIFAKMTIPVGFITRYAIPLVVATLFLGDVDIPQQINIFDKTQRLSDEVLSKAMGEGEGPPESFDYIIVGAGSAGAILANRLTASGENRVLLLEAGGSPNPIMDVPNAQRFFWNSEMNWNYTTVKQSRSCGATDGYCAWPRGKALGGSSSVNGLLYNRAKPKDYDLWANFTGDQSWSWANIKDTYNSIEDYHGYYEESAGANHGYGGEMYVGQLDYLPGVEVFEEALKEKGIPTGDLNGGEDFTYGFTKIDHNIKNGLRWGTYQAFLEPILNRTNLVIYRYAYAIRVETESLGNGTHRAVGVTYERHGAIRTVLAEKEVIISGGVVESPKLLMLSGIGPRERLEELNITRILDLPVGNYLQDHPGVDITGSSGGFRLNTTFGKDLNSYDTILQFIQNGTGPRNGFAYDGGYAPQIMRGYLSSSQNQDDEWPDVHIYIRERYRPSPDEQEEVYFAVDIIRPVSTGTIKLASKDPNDKPIIDPNFYSHQNDMEKVIDVIEIMMDVFMNSTTYQKYGIQQLDVYEPCRGEEFLSRNYWSCMIQERTTPYYHPTSTCRIGPDPSIAVLDSKLNKFFISAKMTIPVGFITRYAIPLVVATLFLGDVDIPEQINIFYKTQRLSDEVLSKARGEGEGPPESFDYIIVGGGSAGAILANRLTASGENRVLLLEAGGDPSPILDIPYAQRYFGNSEMNWGYTTVKQERACGATDGHCFWPRGKALGGSSSVNALVYNRCKPKDYDLWANFTGDQSWSWANIKDAYNRIEDYHGFYEESAGANHGYGGEMYVGQVDYLPGVEVFEEALKEKGIPTGDLNGGEDFTYGFTKLDYNIKNGLRWGTYQAFLEPILNRTNLVIYRYAYAIRVETESLGNGTYKAVGVTYERHGAIRTVLAEKEVIVSGGSIESPKLLMLSGIGPREHLEEMNITTILDLPVGKYLQDHPGVDVKGNNGGFRLNTTFGKDLNSYETILQYVQNGTGPRNGFAYDGGFAPMVMRGYLTSSQSEDKEWPDVHVYIRERYKPAPDEQEEVSFGVDIQRPNSSGTIKLASNDPKEKPIIDPNFYGDLNDMELVIDGIEIMMDVFMNSTTYQKYGIQQLDVLDACQGEEFLSRDYWRCMIREKSTTYFHPTSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5T8</accession>
    <name>A0A1D2M5T8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Defensin J1-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003834">
        <property type="protein sequence ID" value="ODM88282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5T8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036574">
        <property type="entry name" value="Scorpion_toxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57095">
        <property type="entry name" value="Scorpion toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="89" mass="10091" checksum="99F171012DA02FEB" modified="2016-11-30" version="1" fragment="single">RYQSLQEFLKYKQIKRMSRNFSRNHRYCIAIGMLEICEASPGQGECWPKFEGHSQSLCLSSGSCGDICRRDGNEGGYCSALLCYCYGCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5U3</accession>
    <name>A0A1D2M5U3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003736">
        <property type="protein sequence ID" value="ODM88347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5U3"/>
    <dbReference type="OrthoDB" id="416834at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="221" mass="25723" checksum="AE74BAF409D453D6" modified="2016-11-30" version="1">MGLKLCYAPQRAIFWLPFLPEFFLRVKTKDCQVFPQVPQSLQQLLGAALASNSQYEWKLIPTWLEFLKFNFYKGGVLSLGFTSPAWYFYSGLQMFEDRNCSLHRLSPRRYNLLRILFSQRAASKPRTTFISQQQISEMDKPRVWLLAPCYSVPVRTRHIHHPNVELQYYICGTQQFRQLYKDGGIHSPNGFSTVDLEADITNKLTTAESPHFILAFENMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6A5</accession>
    <name>A0A1D2M6A5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger protein-likeB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_18231</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003588">
        <property type="protein sequence ID" value="ODM88451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6A5"/>
    <dbReference type="STRING" id="48709.A0A1D2M6A5"/>
    <dbReference type="OMA" id="NFISHTP"/>
    <dbReference type="OrthoDB" id="7460655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000110">
        <property type="entry name" value="Zinc finger protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="341"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="399"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM88451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="427" mass="50067" checksum="377E4449D7609E63" modified="2016-11-30" version="1">MFTIISAKKQAGNFISHTPRERPHACPFCKKSFANQGNLYSHMKTHAELPEKPYKCSLCSSTFGYKTTWKTHMKTVHTERKLSCAICSKMFATLGNLQVHFRTHTEKPHSCVFCLRSFTLRGNLMQHILTHINEKPYDCSKCSSSFAQPNVLKNHMRFKHTGERKYKCDMCAKCFVSSGDLNTHKMGVHFKRKKYMCSICNMGFLIPFRLRNHLEIHNNRKVHECSQCSKKFKKLAYLNAHTVRSHTEKNDRMSFKCEVCDKGFWFKKDFNAHVKLYRRNGKLWCSHCKLFFNSMETLREHVQLFHKGSLQFLCVMCEARFPGMITLESHILKKHTREKPFSCSQCTVVFQTDRAMKSHVGTVHDKNRPLFPCQLCDKSFVNMGSRDDHIRIHLNEKWIQCTLCKQSFKNSKSLRNHDRKTHRAMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6J5</accession>
    <name>A0A1D2M6J5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003408">
        <property type="protein sequence ID" value="ODM88586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6J5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="6398" checksum="EF1E7C2759545FAC" modified="2016-11-30" version="1">MGIGMGIGHGMVSSHHSSHIGHHGHMMGYPGIGMIGHGMTMGSIHKSYHHGMGMYPGMIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6L0</accession>
    <name>A0A1D2M6L0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UEV domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003437">
        <property type="protein sequence ID" value="ODM88552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6L0"/>
    <dbReference type="STRING" id="48709.A0A1D2M6L0"/>
    <dbReference type="OMA" id="LWLPEPY"/>
    <dbReference type="OrthoDB" id="306304at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052070">
        <property type="entry name" value="ESCRT-I_UEV_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017916">
        <property type="entry name" value="SB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008883">
        <property type="entry name" value="UEV_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306:SF3">
        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05743">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09454">
        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51322">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UEV" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="212"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="311" mass="35202" checksum="A6419A74216CDEBB" modified="2016-11-30" version="1">MSSDENYIRQILQSNQYKDINKTKKDILEAIRMYKGLKPISDRFVFNNVVIWLLDTHPINAPMVFVKPTPDMRIKVSRHVDHNGKVYLPYLHEWTGANSDLLGLIQVLICTFSEQPPVYAVPPGTPQPQQQPAMPSPYGTPYPVSTPYPAMPSMPMPPGGSPVPQPVTTSGGSLGTLAPSLVRSSLLSAVEEKIRRRMDDQYLGAEIMRGTGKQLQEGRDKLERMVKDLNEEKANLERSMELCRKESRELEEEINRAKEIENEPDIDSAIVPPTPLYRQIVDSFVKDLAMADIIYYLGEALTTGKWMWINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M709</accession>
    <name>A0A1D2M709_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003236">
        <property type="protein sequence ID" value="ODM88755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M709"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="215" mass="24627" checksum="384A1FBB2AFCFB75" modified="2016-11-30" version="1">MAKKNCFCCDFNPCPCMSLQKGAISAAITLAVLKVISIIVVCVFVVELDQYLKDEKDKHSGGSVSTEPSVEEMYAPVRKPICCFPRSCRPWNRFGYVIVDLGSAKNTWVHIIWTIGTMACLFIYFFLYGFEFFGTTKKQHMFTSYTIGIYIWKWVEYVIIFYCSLVVGEFRRQLLKERQQQTLEASRVYQVQAEAPAQDQPGDQSINAESQIMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7D4</accession>
    <name>A0A1D2M7D4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Neogenin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_17812</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the immunoglobulin superfamily. DCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003103">
        <property type="protein sequence ID" value="ODM88869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2M7D4"/>
    <dbReference type="OMA" id="GGDHAYW"/>
    <dbReference type="OrthoDB" id="114660at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000028">
        <property type="entry name" value="Neuronal cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010560">
        <property type="entry name" value="Neogenin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF54">
        <property type="entry name" value="FI24025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06583">
        <property type="entry name" value="Neogenin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00014">
        <property type="entry name" value="FNTYPEIII"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903570" evidence="12">
        <location>
            <begin position="32"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1088"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="38"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="145"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="244"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="337"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="14">
        <location>
            <begin position="440"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="14">
        <location>
            <begin position="544"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="14">
        <location>
            <begin position="642"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="14">
        <location>
            <begin position="751"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="14">
        <location>
            <begin position="861"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="14">
        <location>
            <begin position="959"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1205"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1226"/>
            <end position="1275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM88869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1379" mass="152486" checksum="17AC1B900DC6DEFD" modified="2016-11-30" version="1">MVSTMMDKRKSCSCLVLLLSIWISCLNFTQALRFVSEPLDSTLRMKSNNELKITLSCAVERGEQRGKDLTINWNKDGVKLNQSTNGIKITTSQGNRSSLAVSITGPLTSDIIDNYYQCEAVSSEAEGVSTVVLSRPARIRILGPPVFLEHPEDLTSTLGQTARFACLIDKSDDEVKPPTWYKNDAKLSIDNSRMTILPSGSLEIQNVLEADAGAYKCSVDSGSGFSRSGRLYILPNSEKDSAPPVFTAVPKSRTVLAGTDIVLECSAVAHPKQPRIMWLKEGGAIDFTDSETRFTIIGEANLHIRSVTPADRGTYQCRAENKEDSIDVQATIDVVIPPLKTSDQIVNYYAYEKDDVELNCGVSGTPTPQLKWLRNGEQILHGDYFQHPPGSTRLRILGLVSSDTGFYQCFGTNAGGTEQQTMHLRVLRPGQEKPPTQLGPPTNFTATSVTSDSISLKWSPPFIVEAVPVLGYTIYYKKLTDSPRERTVNLTKSAKNPVPPTETTIDRLQPNTTYIFRVQAYGPSGPGVHSNEITVRSVGEDPIVIEDFTAIPTSSSSVQVRWSTASDSVQRWVIFYQEVNGGIFGNDDGRGETLTVNIPQAEIDSLKPFTMYKIKVHAVSRNGPGPEEAVSVRTLSDIPADTPHNFTVEPNSASPNFSLYPQSLRLSWLPPPIEFQNGQITGYKVKHKAKGKKRAETVTTDANTLSLIIPDLEKSTEYQIRIAAMNVNGTGPFTEWMSALTFAKDLDESQVPDRPEGMQARPGVSSITITWTPARSRDGNDILVRGYTIGWGKGIPDVHTKLVDRGRRSYKIDGLRPNSEYVISLRAYNRVGDGIPIYENVRTLEEDDDDFSDELINFLPPPVGLRAITLSPTSIILYWTDNGGYMFRKELGKVLYVVRYMPVDSDNKYSYINTTETSYMVENLRPGTTYEFSVSVVAGHKRSQWSLVAGNTTANSRPPPADLTLVGFTDSQAGQSSVVLNWQPPPSTISHHHDASLSTEDTLQSYIIYYTTTQKEWVEESVPDDVLTHKITGLTPDTTYHFRMSGKWRRSGLGQTTEIKSVKTPKVLTHYQTVANTPHNPIQRPNQIVLYILIGLSVLFALASVALCIYYKRKARDLENNAMGVKKDKKMKKHDPEMMKMTASGKLNPPDLWIHHDQMELKQMQQHQTLLSSSSNEFDLIDDHRTTHSLDKRALRASRRVVTTDDDDLDTGSSTLRRINNKNKHSGSCSSVTVPLSLSSNASSQHNLTHNHGGQYSATSDYGTAQSTNNLSTLTRRGGANASGNLKSFGVPPPAPVITFPPGVGVVTNKSTPHVTDTRSNPVKLQNPPSVHNYFVQSDEPSSPPLQKCYSTEELNQEINNLEGLMKDLVDITAKEFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8U0</accession>
    <name>A0A1D2M8U0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002671">
        <property type="protein sequence ID" value="ODM89406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8U0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="117"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="403" mass="46251" checksum="79D2B04E8DB2CBFB" modified="2016-11-30" version="1">MPLCFRLCPINPPMQTEEQLRTYVTQLQLARINDLEFHRFQLNSQLGSLHQEFQEKEQKLKAEFQAKEQKWRYEHEVDRRLVMAELKLLLLNQNGSGPVPVPPNREPDSEEAAPAELEVMMDELMTTKNKLKDALKEIDELKAVAGINETNFRTQLGIKDARINKLETEVETLKIRLKTSEQKRNVKLAELRMTKEGEHELLRPVKKKGTNLVSDDETEDVKVLASKFTKKGPKTEKAGEATETQMQLVPSSKLPPAQTLPESSDDEVEVEFLGEVNARNALVPVQTGGPPKPKTKQGCKQVVLSSQGPQVQHQDATIPLQKFKCAKCPRRLYMFSQWRYHMEKAHQTTRLHGSVGCSACGKIFDTKRQYFEHRKQFHAGLKRKPLPTPRRSRTRSEDPEYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M960</accession>
    <name>A0A1D2M960_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17213</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002621">
        <property type="protein sequence ID" value="ODM89471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M960"/>
    <dbReference type="STRING" id="48709.A0A1D2M960"/>
    <dbReference type="OMA" id="YECIVEL"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="26719" checksum="69C1E87F61B78E2E" modified="2016-11-30" version="1">MYLGLIDNYLVKIQETTDHTSSFYKENGAKNLEAVVGDLFLAGSESTSFTLSFATLYLILNKNVQRNAQEELDRVIGPSCQVSLRDKPSLPYTEAVILETLRLSSIAPLGFPHRLLVDTMFHGYHLPKDVTVMAGLYTIHHDPKIWGEDANEFQPERFLNENKTRVIHHEALMAFSTGRRVCLGEGLARDTSFLFIASILQRFNIGPDPEYPVTKIETLAGFAVEPKPFKFVLSLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9D6</accession>
    <name>A0A1D2M9D6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phospholipase ABHD3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002512">
        <property type="protein sequence ID" value="ODM89596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9D6"/>
    <dbReference type="STRING" id="48709.A0A1D2M9D6"/>
    <dbReference type="OMA" id="VRTHGHE"/>
    <dbReference type="OrthoDB" id="247542at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008126">
        <property type="term" value="F:acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051792">
        <property type="term" value="P:medium-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="146"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005211-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="408" mass="46097" checksum="619AB5DEF3D197F8" modified="2016-11-30" version="1">MIFLLESPDTLPLSRNLVVFLAGVLIVVFHYVVFVVKKPRLFTGNHELRQFLETHVPTHKESYKPPILLQSGILQTVLSVPFRPGFSKKLNLQREVFSFRDGGEAALDIVLPDNCDNLENGKESLVVLILPASFCTTKTTIVTALVQAVVNSGCTAVVLNYRGACGIQFKSPKFNTFADCDDVAEVIPYLKKKFSSSRLMAIGQSAGGMVLAKYIRENQKEAKEYLVTAMMISMGWDMVRGYHNLNAPHFINRLVIHRQHLSWMKLNAANMLRYSKQMGEKAWKPTVDYKKAMTSKTIYDFDQHLLVPQFEYESVKHYWQDASSRGNVLKFSIPVFCLNAEDDPATPGKLLPYEEAEDSNSKLALLVTSKGGHNGFLEGMIQRPEHFVERLVREYVTAVRTHGHELPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9L8</accession>
    <name>A0A1D2M9L8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002451">
        <property type="protein sequence ID" value="ODM89675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9L8"/>
    <dbReference type="STRING" id="48709.A0A1D2M9L8"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052740">
        <property type="entry name" value="CE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985:SF8">
        <property type="entry name" value="CHITIN DEACETYLASE-LIKE 9, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="36558" checksum="3DF1D0726105E467" modified="2016-11-30" version="1">MNEVRLVSGLSYNNLCQTITPAPACTDHIRDDFQIADVAETIFLESSLLQESHRFCSTEGIPTMRPSQQHFSSRTNTPITAWVHELYRRNHDIALHSMTHNPLTAYWASLNATMWQKEVVDQREQLSNFARVPPTAIQGLRAPFLQIGGDPMYNVLKTSVGFWTVPMLDMIGDNNAGCAMVDTCTPVPETSDATYNLLLRNFNDQYAGAEANRAPFGIYTHALDYLGTKNDVYIVGISQALEWVKNPTPLDQIPSSNLFKNPTRPNNCPTIYNCRYAPEQTPFPKKGICLFVHHVLPCTHGLEIHLEGHKSVSQSTAKIITGKQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBN8</accession>
    <name>A0A1D2MBN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002030">
        <property type="protein sequence ID" value="ODM90332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBN8"/>
    <dbReference type="OrthoDB" id="8294558at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10394" checksum="35350484AF5CEFE3" modified="2016-11-30" version="1">MRETLPTVADNRVAARERMADDKKNGADYYLMECTNLVQQSTPMFQEAEKSLERGQKLYQCRRCRGPVPSPVVSAEPKESDDREEPNLYPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDM9</accession>
    <name>A0A1D2MDM9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">G-protein coupled receptor 98</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001674">
        <property type="protein sequence ID" value="ODM91090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDM9"/>
    <dbReference type="STRING" id="48709.A0A1D2MDM9"/>
    <dbReference type="OrthoDB" id="418484at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026919">
        <property type="entry name" value="ADGRV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46682">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR V1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46682:SF1">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR V1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM91090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="101" mass="11461" checksum="B05F08B4C2DBF947" modified="2016-11-30" version="1">MINQGSEGTLVFKHGETLRTIEIPIVDDLKTRRDECFEIELANPEGGAKLGRITKMAITISNDDEFNSVLQRMMVMTTHNIKSMQVHHETYKTQLESVNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEZ1</accession>
    <name>A0A1D2MEZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001501">
        <property type="protein sequence ID" value="ODM91569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEZ1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="636"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="843" mass="96250" checksum="BCD29765BE710D63" modified="2016-11-30" version="1">MDSDGVTLTFRKLSSPSHSKFTEILSDFEKLDFAHDKCTNVEDTLNYNEGREANPFDKMGNYYGRHKDVFLFNRILRDKKMRMKIDELLSVKDDDIKTRFFTRLQLYLERLEVGEQEAKRFLEEALVAEAFYTGPRGVEKENLNLNLGNDGVLRIGTVFDGKLDELKRLKVHGNGRRLVTVLKNGEQKNYSFTKATSCDMEIKWVANEKRCQVEIKVDGGGKLVKKAMVDGKQVKLEELIPLAKQNKGVLIRDRRLYQVLEECLQKGMFSDEKEEVEEEKLIVKEVLKVDDDDAQVVEFFAELGKNLDVLKEQGVKDPLGKLRSDYGRNGNVFILKKILKDELLRERFLNLVKESLGGDAEKLERKVDKMLEKFLQGEKLAQKIVGDEEIDAFVAGGENGNTNLNLNLNKKRTELEKLFEKAAAKGVKRIKVFGGGQRLLTILQVGGKQRNYSFRDLAQCELDLSWKAGSGNDIKTCQLVLDISSGKIFALNGAVNGNPVALEDILELAKQNRKVLINGKPLHLVLEKILAGGDGGSIVSMKSIGSQEKLTFHGIFKEQQLLQFDGSDEQRFPDAVDRFFERLLTLDFSEGAEPNAFNTLAKYYGREKKEDVFFFQTILRDPNMKQKMMSMIKSSTKCEENQLQQFNRRMERYLKRIENGEKDAKEFLGDGNAFFHGYHVAHPEHPRNIHENLNINLAKRTNITFETGDNLFAKVIPAIVQEQSELRRVKMYGNGTRLATVLKLDGGQRNYDFEDEAGCDLEVGWVAKEEEMECTLILNVEKGKLIFRKGLLNGDEMDKEKIIEFAKENKIVFIKGKNLAEILEEKTVDPDDHWEVLFDGNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF59</accession>
    <name>A0A1D2MF59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Platelet glycoprotein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15039</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001465">
        <property type="protein sequence ID" value="ODM91645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF59"/>
    <dbReference type="STRING" id="48709.A0A1D2MF59"/>
    <dbReference type="OrthoDB" id="10024078at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF51">
        <property type="entry name" value="LYSOSOME MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="334" mass="37581" checksum="599393817DB5FD12" modified="2016-11-30" version="1">MYKNGTITATYSVKSTKETPFGKILTYQGYPSLGFWPPSSHCDSLADSLDFFTFPKRITKDTVFNIFLPENCRSLQLRYVQEDVFRGIPVFVFKFPLEQFSNNLQNDETACYCLNYHNTSDPTCLDAGLMDYAGCSKGAPLLGSFPHFLHANPRHLKNLRGISPNKSLHESEIMIEPITGTPLYAVRRFQLNLRTRPIPLVTYFENMTERIVPLAWFEHILEVPSTTFTAVKQKLEELKLEADAKDIYQHDENPIEEMDDNTLFASRSGFPGSSGLIEEESPSNEIRNASTAPSIGSHLHSSYFAIVTTALVLLLSRGGSGFISETSLNLNERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFH4</accession>
    <name>A0A1D2MFH4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_15038</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001465">
        <property type="protein sequence ID" value="ODM91644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFH4"/>
    <dbReference type="STRING" id="48709.A0A1D2MFH4"/>
    <dbReference type="OrthoDB" id="6127067at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008074">
        <property type="term" value="C:guanylate cyclase complex, soluble"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070026">
        <property type="term" value="F:nitric oxide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019826">
        <property type="term" value="F:oxygen sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038060">
        <property type="term" value="P:nitric oxide-cGMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070482">
        <property type="term" value="P:response to oxygen levels"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000007">
        <property type="entry name" value="Guanylate cyclase soluble subunit alpha-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1520.10">
        <property type="entry name" value="H-NOX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.260">
        <property type="entry name" value="Haem NO binding associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038158">
        <property type="entry name" value="H-NOX_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011644">
        <property type="entry name" value="Heme_NO-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011645">
        <property type="entry name" value="HNOB_dom_associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042463">
        <property type="entry name" value="HNOB_dom_associated_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45655">
        <property type="entry name" value="GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45655:SF10">
        <property type="entry name" value="SOLUBLE GUANYLATE CYCLASE 88E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07700">
        <property type="entry name" value="HNOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07701">
        <property type="entry name" value="HNOBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="11">
        <location>
            <begin position="418"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="606"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="871"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="755"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="871"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM91644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="982" mass="109281" checksum="0EA7D557E8E7012C" modified="2016-11-30" version="1">MYGLLIENLASFIRVQWGEGKWDSVRKHAGVDAPSFSIHHVYAETLLTRLARSACQILGVDEKSFFEAMGVYFVEYVGHYGYDQMMCVLGRHLRDFLNGLDNLHEYLKFSYTKMRAPSFYCDSETANGLRLHYRSKRRGFVWYTMGQIKQVAKHFYDQDIEIELISEELDGETMHNIFQLTFDNQAFVEHESLTSVMRKESQLPIRASIIFELFPFCIVFSTEMVITYTGHALLTILKELVGQTMGEAFEILRPLIAFSFNTIMERRNNIFELVTTSPIKEENLDDILEDETVEGVHLRLRGQMLFMEEWNMMLFLANPNLPDLPSLVAAGIFINDLSLHDCSRDLVLAGTQQSVELKLALDQEQHKSKKLEESMKKLDDEMKRTDELLYQMIPKQVADRLRKGESAVATCEVFEKTTILFSDVVTFTDICSRITPMQVVAMLNHMYSLFDQLTERNGVYKVETIGDSYMVVCGAPTQEPNHAERIADMAMDMIDASQAIKDPSREGEHLKLRVGCHSGMVVAGVVGVKMPRYCLFGDTVNTASRMESTSEASKIQISEFCKAQLAPTYKVELRGTVNVKGKGEMSTFWLHGREARVPLTKVQAGSFDWSDPSAQQSRRYSKSSDKGSRKSSVISTTEATETKSRDASRATTPLPPQKESASEQPKVTPPPKVESQPSTSKAATPAPQPKVAPPLIKTPAITSEPQPPSPEPPTDASESRKTLKPQKTLSVEQDAAGNKMELNAPGKDLYRQARRLSLAIRSRSPSPAASERGRSNATRKTSNSSTTSSIEQKPEVKNGDNKDQASTSSKKVTLVRQVTLVDLPKKLAEVMNKPSDTVNIVKVQAPKNISVTDPSGKTSEEDIIMIVPATPTNSQSSEDITASANENGDGVDGEQDRESFLINVKMKKGNRDNGPNGKPKGLRTTINGIAVGISRLPKNQALRKKLRENKIAVVTADVLTDIGCVAFADKQKQVISQACSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFX2</accession>
    <name>A0A1D2MFX2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DBH-like monooxygenase protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14806</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001389">
        <property type="protein sequence ID" value="ODM91875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFX2"/>
    <dbReference type="STRING" id="48709.A0A1D2MFX2"/>
    <dbReference type="OMA" id="SANGPEY"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042420">
        <property type="term" value="P:dopamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.230:FF:000001">
        <property type="entry name" value="Monooxygenase, DBH-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028460">
        <property type="entry name" value="Tbh/DBH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00767">
        <property type="entry name" value="DBMONOXGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903952" evidence="5">
        <location>
            <begin position="26"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="6">
        <location>
            <begin position="44"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="574"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="660" mass="75444" checksum="BA0BBA02D3D59880" modified="2016-11-30" version="1">MEGISVRTFITFGFLLICFFNWATCDYRTEENPYKHFAQVDPEGNYILEWIVNWDTKRVTFNVTVATNGYIGFGLSRRGQMNGSDIVIGGVNRNGRSYFTDCHGTGEIPEIDDSQDWSLLDAWERGSRTFLSFSRPFDTCDDEQDVPITDDLLQVIWTYGETDDEIQYHFQNRGAMPVYLLDPDLVPRSLDPRVPNNGQQPLLDDSTRIFEMTTTRDVPAQDTMYWCSFHKAPTTSKHHIIGFDTLFPTEKDETHVHHLVIYRCHPPPGVNPASLFEPQIASGGGECYFIRDPNPMNTQYCTEDVFLWAVKGRPTFFPEHVGMPLSANGPEYYLLQTHYDNPNLESNLRITFSLQAYYSSVIRPNEAGMITLGTITPGSTSIIVPPGETNHTIMGMCAPGCTDQMFPEEGITVFASLLHTHIRGRGARYHHFRGNTELPWILTDENYDFNYQQYRVLREERKVLPGDLLVNSCTYDTTDTNGTAVIGGFSTRQEMCTAFLWYYTRSNSHAFCRSELKSDGYLNLVGVRTTQWNQERRAMVITSPARYSGISMADYTTNYVDWTVEMREELQRRQIYDPQSSQCPRFTPDDVPTESQLSTEGAREGTGNQQPMSSFPSKVRLYQPSSQCVRRRNQIGGQQQRGKTIREKERSKGRRGWSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH56</accession>
    <name>A0A1D2MH56_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prostaglandin F synthase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14478</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001298">
        <property type="protein sequence ID" value="ODM92204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH56"/>
    <dbReference type="STRING" id="48709.A0A1D2MH56"/>
    <dbReference type="OMA" id="KLPWTGM"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000006">
        <property type="entry name" value="Aldo-keto reductase family 1 member A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="343"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="608" mass="69178" checksum="5BC067EF5B92F513" modified="2016-11-30" version="1">MIESQSRRFIRLPNGQNMPIVGLGLWLANDSQQLENAIDHALSVGYRHFDTAAFYQNEEILGKTLRKWIDGGKVKREDLFIVTKLPWTGMTVDKVEFFMKLSLKKLQLNYVDLYLCHMPIGLKFVNENNFVPTDENGKVLWDTSTDIIAVWKEMEKLVDSGRAKAIGLSNYNERQVEKIMKNARIPPASLQVEIHAYFQNRSVVSCAEKHNISVVAYAPLGSPGRKAIDFQVVKFEIPNIIEDPVVLDIAKKHKKTAGQILLRFLLQQGIAVIPKSTNPDRIKQNLELFDFSLSNVDMRRLEGLDKGSDGRSFPGFPGQNAHPEAPWKHQLLTLPDGNKMPLVGLGMWQTDDATELEAAVDAALNAGYRHFDTATLYKNEDKLGNVLKKWLDSGKVKREELFIVTKLPWTGMAPERVELFLNSSLRKLQLDYIDLYLIHWPIGLKFRGEDDLVPMDGDKVLYDTTTDLEAIWKELEKHVESGKLKSIGISNFTEKQIERIMKVAKIPPANHQIEIHVYFQNRKLRDYSEKHGITLAAYGPLGSPGRDPKGFPGMSFEVPNLLNDPIFNFELSSVDMRRIEALDRGDKGRSFPGFPDMRIHKECPWLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHG2</accession>
    <name>A0A1D2MHG2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein SHQ1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14341</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SHQ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001260">
        <property type="protein sequence ID" value="ODM92342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHG2"/>
    <dbReference type="STRING" id="48709.A0A1D2MHG2"/>
    <dbReference type="OMA" id="HNIESAW"/>
    <dbReference type="OrthoDB" id="73639at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039742">
        <property type="entry name" value="Shq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048696">
        <property type="entry name" value="SHQ1-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007009">
        <property type="entry name" value="Shq1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967:SF0">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04925">
        <property type="entry name" value="SHQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21413">
        <property type="entry name" value="SHQ1-like_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="28"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="469" mass="53591" checksum="7FA0A0160922C877" modified="2016-11-30" version="1">MLLWTNIVETELGRECAAENVLFVGEIMITPKFELSQTETHLIIHVWAPYTSVKDTEIEVVEEEVVIFASSPYYLRLTLPGRVEETGESSADYNADDGKYTISLNKVVPGTHFPNLEMLTTLLLPKNQKKRVKPLIEVIGEDGVKENSTTVDFISEDDWFIEQTPMEEDSPASACSSLLNKHSYGFLSSHSGLQDKYVEELAQVSEIRNPDSCSEAQRRSLRLEKERVDFSDEHYLADLMENEEVGSSLQFKFDLSSLKELSEKNKEKMKDLGNREFLVDKVGLKKSFLGLVDILYAYCYDWRITEGAHCCESPWNIARLSGTLSWFDSFDSVRDVVHCCMRRSLVYPLSRHWLLSRKVMTDVVKVLKSGPVAILICFLDILDIFGKKEPYYLLNQLYIEEYCVWIQQIGKDSTNLTSIVVALEKAFPNYKKEHVGFDLEELEAAAAACEEEEAMEEEISDYVRNVAIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHG3</accession>
    <name>A0A1D2MHG3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001225">
        <property type="protein sequence ID" value="ODM92447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHG3"/>
    <dbReference type="STRING" id="48709.A0A1D2MHG3"/>
    <dbReference type="OMA" id="DAWHMAG"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904031" evidence="6">
        <location>
            <begin position="17"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="167"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM92447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="427" mass="45702" checksum="CB120A3C534F8A24" modified="2016-11-30" version="1">MIRQLLFAILVGVAFGTPSLKMNQPLSQALKNEKVTNVVVTFKEGTSQLIRSFSTARSFASHAQKVTTLKSSLEVLATNTQQNAISILQGNGTKFQSFWISNQLFIKDASRELINALAALPEVSQVRKEKIISIEKNIYSNSPLNVEWGIDKIEAEAAWSLPGGNKGEGIVVANIDTGVRSTHEALINNFRSAKSWYDPYDLTDNPIDLNGHGTHTMGTIAGSGGIGVAPEAQWIACRGCYQYSCTEEALLACGQFITCPTDPNGENPDCSQAPNVVSNSWGFYPGATFYDEVIDTWRAAGIVPIFAVHNYGSCDFVTGPGDNINVIGVGATTEDDGIASFSSRGPALNGAIKPDICAPGGVAALLLSQNPNLSYDEVKDLLQNNAERDLLAAETCGGIPSDVFPNNVYGYGRVNARESLANAINEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIZ7</accession>
    <name>A0A1D2MIZ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Centromere protein V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001106">
        <property type="protein sequence ID" value="ODM92969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIZ7"/>
    <dbReference type="STRING" id="48709.A0A1D2MIZ7"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052355">
        <property type="entry name" value="CENP-V-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620:SF1">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620">
        <property type="entry name" value="CENTROMERE PROTEIN V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904116" evidence="2">
        <location>
            <begin position="26"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="23987" checksum="8DAD48BEF3AA6502" modified="2016-11-30" version="1">MEKFWVVVCIIAVVCLLLESSPSNAKPDEDEDPDSFGSWFSGRTNETWKGNGEITPNKTTKEVEEGSPEGRHLIDFKFHIFDFAKNKKSKNGDDDEDEEYEDDEEEEELFSLHKETKSSFHRSCIKLQAGLWPHGANNVHVWDSQAQAYVLTQKCGVQSFYIPRSNPDGMAIMPHCIDGPLPLKIVVEKFDGQHWENAMEKSAIRDRSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK12</accession>
    <name>A0A1D2MK12_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein-likePLAG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13361</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001022">
        <property type="protein sequence ID" value="ODM93323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK12"/>
    <dbReference type="OrthoDB" id="7852576at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="295"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="373" mass="42298" checksum="1A24B9F269FD3BE6" modified="2016-11-30" version="1">MESPNSLKISDDIEVGLLLDKLIAANSTTVFCTKCKNVVSSICQLFHELLTVQLRLSIQLGELGDFLETSDVFQFHNKSLAEQLGVQNSTKDVKRLRKLLKTQCERKRNEGLPDVRIKRLVKQRQWSEAAMENEATEETLDMEADPFDESRQFGAENGNSCLFQSDLSSESGSNSDSDSQASESGSSSSSPSEPPQKRLKLGQEEYPCGVCSKAFPTSKQKRTHIFQCHNKKRYRCPECNIPIKSKVLKQHLVEYHKPQTHICNYCRKTFKTGKYLMDHITLTHSNLLLQHQNWPKCPSCHKTFERKHKLSRHLPKCSSTSNPEATLQKKPSDTELGESFTSEHSSKAQFDASSVTHQRKLTFANIAQKFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK15</accession>
    <name>A0A1D2MK15_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter C family member 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001003">
        <property type="protein sequence ID" value="ODM93387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK15"/>
    <dbReference type="STRING" id="48709.A0A1D2MK15"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF448">
        <property type="entry name" value="FI20146P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="133" mass="14860" checksum="81E396BAD9072B24" modified="2016-11-30" version="1">MDEATANVDPQTDNLIQKTIRTKFADCSIITVAHRLHSVIDTDRILVLDNGFVMEYDHPHRLLQNPNGILTSMVQHTGKSSSALLRKIAAETFSNRRASFQADVVDELAFLNEEEFVEAVLGNDFSNVDNNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK99</accession>
    <name>A0A1D2MK99_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger C2HC domain-containing protein 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001011">
        <property type="protein sequence ID" value="ODM93361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK99"/>
    <dbReference type="STRING" id="48709.A0A1D2MK99"/>
    <dbReference type="OMA" id="LAKFCYE"/>
    <dbReference type="OrthoDB" id="10066537at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026319">
        <property type="entry name" value="ZC2HC1A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049899">
        <property type="entry name" value="Znf_C2HC_C3H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555">
        <property type="entry name" value="C2H2 ZINC FINGER CGI-62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555:SF5">
        <property type="entry name" value="ZINC-FINGER OF A C2HC-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13913">
        <property type="entry name" value="zf-C2HC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52027">
        <property type="entry name" value="ZF_C2HC_C3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2HC/C3H-type" evidence="7">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="424"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="625"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="806"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="722"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="812"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="879" mass="97657" checksum="F919F17705DD39F6" modified="2016-11-30" version="1">MDSACMDISDNSSMSIDTKSELPAWRMPISTSFSSSLRERLNSPPKTILDNQKCPVDRLLSTSSEEESDMQNNVKNSNNNNNSSAMAYENKPAVSQNNKLEVEDDDEEGKLILILLPCIICNRTFSPEALERHAKVCTKVNTKNPYKPNRGTFDISEKRKKGTLLEDFIPPPTFDALTDNRFGLSRGSRNRSSLRGTSCTTRSTLVSTTPAPNTRRERSVSQSRERSQSRAPPSVTSPTDYPYDDTSEFGSNNSEENNLPDLPRYAQPIAPKDVCPYCNRTFGIKSYDRHVEFCKEIFERKRYEIQPTPKEKEEAMERQEIRTKYRPMKSSSSCSSLRSMSPAKDFASMAMKLFGGLRRTEGSTNLYFNQIKNNLKKSNESIAASCYGDYTRGVRRTSPSPVRTSSTAASAANKLNNLLTKSYLHQQQQQHHQQQQQQQQLHQQSFNQYHHQSGSLLPMRLNTSSNIPKMTKSTDSLNSGNNFAHVSSSGYGQPPSVMMMNSNNNSFMRNSRSRSSLHKNFFRTKRAEPEGTENTSTLSQSPTATSPLIITPVNFYSKGNKTLSSLEIDNNKNKTGSSGATGELRGMMMTENVRPPGTSLLTSDPDYDPYEKAAKQLEELLKTTPIKSSKRSSRRTGLEKAFESVGVPSDMPDMPSLGKSKLGRTQSLDYNSDPFGRTSMKRATDPFGIGSGAPMTPNIDDSYWDQIFRKGDNQHGNNNNNPETISSQEESDTSGTSDTAKSRAMSNTSSADSAFSRSEVNDPEFEALESIVSVGDTTTSTNRYKKTHEDRNKVDLFSTNKLLESHHRTVPRSPSASIDQGRTPMDTTPVSDSRQKSSENSSGSGGAVLAKFCHECGTPYPTSVAKFCPECGEKRVSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKN2</accession>
    <name>A0A1D2MKN2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000954">
        <property type="protein sequence ID" value="ODM93567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKN2"/>
    <dbReference type="STRING" id="48709.A0A1D2MKN2"/>
    <dbReference type="OMA" id="QHHISTR"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="432"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="744"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="754" mass="79651" checksum="BA331CB6EA626786" modified="2016-11-30" version="1" fragment="single">MADLFVINQTIDADILFLKSLRKSQLMNMSVIKTRRSNDRSPIQTSRQTAIRIRAPCFQALQSKESKIPVGIAVAWQRLVTSTSTNPTAASVMTTKAESGGSGSDHPQLLHFPAKQKVAAAAATHNHHHHNHSSSISSSTSNNNSNNPIYANRNNSGDNNNTSSSSSAGGSSSNPSANKNGYGESSDISVGSSVNSGNNIIGRPLSACGEPSGGGGIVPFCPSAASPLSRPLPSSSVPPNLGFPTASSYQYPHRGPYIDYPYGIAGNSGSGGFAMPSSPHHHHHHHQQHLVGNGHFWGLENPSVPLLSPGMPSPGASEYLQLSMQQQMQLHQQHLLATTRQSSLPLSSSSPYNPYLPFLYPHHQDPSLAAKSPYYDHFFHQNELIRHHQQQQQHQQSQLLLSQHQQQQQHEAFQHHQQQQQQLQHHSHQTDTGNSNNSGITNSVNSSNNNGSSGRTSSTNNSNVSVSNVGGFDLLANNGSQHHRAIPMQVASSRTSIPLLSPSPTGGLRTSTPTSTLVIIIIINTAAATTTATIVTSCNTSTTPHQDHSSSQSASASWPAASPSTGVELSSSYSSSYSSASSPSPSFLLLHHQQQHPHLFTSSSAALSPKSLTSSTPSPVTVHDFNSGLNVVIGNSNGNSGSSSGNNNLSSAMLTARKCATPSPISLTPRGLLSPFGSPFSPSPVPTHPGNNNNNNNKDLVWKEDAAKIKPIPTKAHAGGSVDELRTMIANGHGATMEKGGGSLTTTPTSSPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKZ2</accession>
    <name>A0A1D2MKZ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Guanine nucleotide-binding protein subunit gamma-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_13086</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G protein gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000948">
        <property type="protein sequence ID" value="ODM93595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKZ2"/>
    <dbReference type="STRING" id="48709.A0A1D2MKZ2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031681">
        <property type="term" value="F:G-protein beta-subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00068">
        <property type="entry name" value="GGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.260.10:FF:000001">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.260.10">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001770">
        <property type="entry name" value="G-protein_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015898">
        <property type="entry name" value="G-protein_gamma-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036284">
        <property type="entry name" value="GGL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13809">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00631">
        <property type="entry name" value="G-gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01224">
        <property type="entry name" value="G_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00224">
        <property type="entry name" value="GGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48670">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50058">
        <property type="entry name" value="G_PROTEIN_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="G protein gamma" evidence="9">
        <location>
            <begin position="44"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM93595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="13591" checksum="8FFCD4BBF01B962E" modified="2016-11-30" version="1">MYTYHRERFLYNFNWQFERPVQVLPTLREMFFMSDMREPEYIGFMSTLQQQRLIVEQLRREAAVRRINVSQAVEEIKKFVQDHQREDCLIYGFHPPKSNPFREKNQCQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLY8</accession>
    <name>A0A1D2MLY8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Facilitated trehalose transporter Tret1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12626</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000867">
        <property type="protein sequence ID" value="ODM94060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLY8"/>
    <dbReference type="STRING" id="48709.A0A1D2MLY8"/>
    <dbReference type="OMA" id="IGSFFQW"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="28"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="384" mass="41431" checksum="3517A60E2F7D8C36" modified="2016-11-30" version="1">MKKGKYTVNNGDMEMGPACCGSNSHRMPQYLAAATVTIGGFSLGNVLGWSSPAIPNLANSGDFPDIQNYQKAWIGSLVTIGALVGACCSGYLIEKIGRKKSLLVVGIPYIIGWFTIALAHQIYMLYVGRFLTGFSVGALSLVAPVYLCEISQSDIRGFLGAIFQVTVTVGILFTFILGSVTSWKLLAATCGIFPLIFTIFSSFLPESPRYLIAKGRSEEALKALSWLRGSDLTNPSKEVLEEIDENASYGQFLGESAHWIPLASVMAFNAAYCGGVGCLIWTVMSEILPNHVIGFASGLATTFNWTLAFITTRFFQDLNDSLGIHNTFWLFAGACGAAVLFIYGFVPETKGKTLDMIQKENFQQNGTRSVEDIASVASSTADLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMP8</accession>
    <name>A0A1D2MMP8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Four and a half LIM domains protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12383</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000829">
        <property type="protein sequence ID" value="ODM94297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMP8"/>
    <dbReference type="STRING" id="48709.A0A1D2MMP8"/>
    <dbReference type="OMA" id="SHWHERC"/>
    <dbReference type="OrthoDB" id="274660at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030018">
        <property type="term" value="C:Z disc"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09430">
        <property type="entry name" value="LIM5_LIMPETin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09432">
        <property type="entry name" value="LIM6_LIMPETin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000013">
        <property type="entry name" value="Four and a half LIM domains 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000070">
        <property type="entry name" value="Four and a half LIM domains 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000066">
        <property type="entry name" value="Four and a half LIM domains protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF4">
        <property type="entry name" value="PROTEIN ESPINAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="71"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="133"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="193"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="28691" checksum="97791859D1FA55CF" modified="2016-11-30" version="1">MGDMKEVGGDLQDHHIADLMSRGLNLKKKNGKHYLATKTVTQPKRLNEQDDDIAILTMILPGEKFECVLKKNCLMGDSKANKLGTKKMEYKTRQWHEKCFVCCVCKSPIGTQSFIPREQEIYCSGCYEEKFATRCVKCNKVITSGGVTYKNEPWHRDCFTCTHCNSPLAGQRFTSKDDKPYCADCYGELFAKRCCACSKPITGIGGTRFISFEDRNWHNDCFFCGTCKTSLVGRGFIADGDDVICPECARQKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNQ9</accession>
    <name>A0A1D2MNQ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Solute carrier family 35 member E1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000801">
        <property type="protein sequence ID" value="ODM94491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNQ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MNQ9"/>
    <dbReference type="OMA" id="MFATWYL"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="41"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="339" mass="37946" checksum="C1E3BC2B28CEC882" modified="2016-11-30" version="1">MSSTDISVKIYKRHDDATGSHSFKDLGTMLDLVLDFQFQQRKQLLNQFEYPMTLTFVQLLSISVYSIPLLRTVVNSSNNNHVATIPDSLYWKIIVPLAVGKFLASVSSHVSIWKVTVSYAHTVKATMPLFTVVLTRVLFNERHSTQVYASLVPIITGVCIATVTELSFNTTGLITALLATCGFSLQNIFSKRVLRQTNAHQFYLLALLARLSLLMFTPFWLLIDVRSMFYHSFENTNVESVICLLVLDGFLNFVQNIFAFTILNLVSPLTYAVANATKRIFIITLSILLLRNPVSYANALGITIALGGVFAYNRAKVVEKRGKTYLPVYNSGGKHNDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPD5</accession>
    <name>A0A1D2MPD5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11736</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000732">
        <property type="protein sequence ID" value="ODM94939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPD5"/>
    <dbReference type="STRING" id="48709.A0A1D2MPD5"/>
    <dbReference type="OMA" id="FRIINME"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="284" mass="32951" checksum="C482F0A48752255B" modified="2016-11-30" version="1">MQDPKKYENNKSGAEEAVRVFLPKLFQTMKWSGSENVLDYGSGAGSAGFNYILPEVHNCDSKMYSVDVSIKMFEFAKKNYSHERITYGVGDVLDNTFPFEDVKFDKIFALHVLHFVRDIRTMLSGFHKILKPNGQFGFTTLTCNAWIFRSLKELSESENWSPYMKDYSKYFPSWLDFPKGREQQDIRELFQSSGFHVVHLEFLRDRDYQFENINTNTFLEICAACNPCSNNIPANLNQAFKEDLRKLLTGYAGIPTNSKRINFKHDYIWGVIEKGKEQDINSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPS0</accession>
    <name>A0A1D2MPS0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD kinase 2, mitochondrial</fullName>
            <ecNumber evidence="6">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NAD kinase domain-containing protein 1, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_11865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>NAD(+) + ATP = ADP + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000746">
        <property type="protein sequence ID" value="ODM94814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPS0"/>
    <dbReference type="STRING" id="48709.A0A1D2MPS0"/>
    <dbReference type="OMA" id="WHFNINK"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012355">
        <property type="entry name" value="NADK2_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13158">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13158:SF5">
        <property type="entry name" value="NAD KINASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017565">
        <property type="entry name" value="Kin_ATP-NAD_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="475" mass="54014" checksum="CECE90233E60FF83" modified="2016-11-30" version="1">MRFHFLRQTTTSYLCMLERGRHGTSLFAPIMKYAFSPRLHLINRSLHTTVFQPKRVLILTKLSRLEFEKLRQPEQSDGELESVLRHRGSDYSTLLYHHYIHKGCESRVHKCFQEFGVETRLVNRFDYTQENIDWADVIVTTGGDGTFLMAANRIQDRNKPVIGFNTDPTRSEGYLCLPKKYSVNVREAVRKLFEGKFLWTFRRRIRITLTGECVFEPPVELHDQQLAHPEFRFFDCLQEQHQSAATCEAPANSATQRTRVLPVLALNEVYFGECVSARVSYVEVGVDGGEKVKSKNAGLCVTTGTGSTSWSYNINKISTSMVKDLFKIIEEDENEQTIASSGIPQNKVIRSTNKLLIDRITSRYNNQLIFSPESGHMQYTIRDPISSYTLPYANEICPRGLAKRLDVRSRCFDACLVIDGGLSFSFNDGTHATLEVHDSDALRTIVDVSNCGSEIGNHNFNSNNDNDVPPKSKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ77</accession>
    <name>A0A1D2MQ77_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chorion peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_11768</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000734">
        <property type="protein sequence ID" value="ODM94915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ77"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ77"/>
    <dbReference type="OMA" id="YNDWREV"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09823">
        <property type="entry name" value="peroxinectin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.640.10:FF:000003">
        <property type="entry name" value="chorion peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022700">
        <property type="entry name" value="CLIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00680">
        <property type="entry name" value="CLIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Clip" evidence="10">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="808"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="841" mass="94363" checksum="502F2C8AC4FF5539" modified="2016-11-30" version="1">MNDGRRGSVAAAGQRFDIVFDDAPTQNFPTCQTPDKRQGLCKPLAQCAIFYAEIPSLLERPCQTRSAQNGVCCPLDKTSNGKPSTGGPKFPIRPGVGNDGVLSSPPPPDVPIPKISARQLQEVAEMSLKTFKIRIDRIQDILFNKKSLPLENCPSVCILKHIPICINQVTIPKGTPAASHQKFFATTNQVLDIGSNAQLNLETSMNVLNNFQLTPLQGTFALPKFSVKGTAAEKACPGESQCNPSYPYRTIDGSCNNQENVDWGKSQTAFQRILQPKYGDGLNSPRVTATGQPLPSPRLVSDRFIPDENRPYRNLTLMVMQWGQFVDHDLTHTPIVKGENSTGISCCENGQPLEASLRHPDCFPIEITPEDSFYKQFNQRCMEFVRSLPAPRKECNLGPREQMTQVTHLLDGSMIYGSTERRATSLREGVGGRLLVQTNGGREHMPANPNECSDANQEKFCFRAGDLRVNEQVHLALIHTIWFREHNRVARELEILNPHWADETLYQETRRIVIAELQHITYNEWLPLILGPNYMRTFELQPTQKGYTQLYNPSIDPSVTNAFASAAFRFGHSMIQGVVKMFNPFGASRNKPFSQTQFQPFEVYDSCDDLVRGLANQESQRMDRFASQAVTNHLFEGQSGFGLDLFALNIQRGRDHALPPYNDWREVCGLKRLNSWRDFEAVADKAMADSLSTLYPNVDEVDLFIGGVSEKPLDGAVLGPTFTCIVGDQFARLRRGDRFFYEEVTARFTEAQLDQIKKVSLARLLCDNSDDITVIQPLIFQKASFLNQRMPCNSESIPGIDFRFWTEKRRGGGSGQTQRQNERPRGGSGQGNNNSNRRRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQL6</accession>
    <name>A0A1D2MQL6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_11540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="6">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000706">
        <property type="protein sequence ID" value="ODM95151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQL6"/>
    <dbReference type="STRING" id="48709.A0A1D2MQL6"/>
    <dbReference type="OMA" id="WAGENND"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000001">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000003">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000004">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF177">
        <property type="entry name" value="ANNEXIN B10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0041">Annexin</keyword>
    <keyword evidence="3 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 6" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="35338" checksum="B113BA188932CB3A" modified="2016-11-30" version="1">MGDAFDPTIKPHYPFDALEDARALRAAMKGFGTDEDAIIDVLTKRCAGQRMEIETEFKNEFGRDLIKDLKSELGGKFEKLILALMEPYYDYLAKELNNAMAKIGTNEDVLTEVLCTRGNAEIALINEAYGRLFGKSLEDDISSEVSGHYKRLLVMLLTCSRNEHVVEPELAADMAGSLYDAGEGTLGTDEEAFTTLLAHHSFYQLKMVFDEYEKLSGKTFQQAAESELSGDLKEAVLTIARRTESLPRYFAERLKDAMKGAGTDEAALIRIIVSRSEIDLAAIKKEYMALYHKTLESAIKAETGGDFEKALLSILEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQP6</accession>
    <name>A0A1D2MQP6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000701">
        <property type="protein sequence ID" value="ODM95188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQP6"/>
    <dbReference type="STRING" id="48709.A0A1D2MQP6"/>
    <dbReference type="OMA" id="HCEQAGA"/>
    <dbReference type="OrthoDB" id="2449818at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.20:FF:000006">
        <property type="entry name" value="Ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000002">
        <property type="entry name" value="Ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.20:FF:000009">
        <property type="entry name" value="Ribosomal protein L10a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_uL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="217" mass="24412" checksum="7B34CC1FD6B6C7FC" modified="2016-11-30" version="1">MSSKVSKEMLLECVNAVIQSSQEKKRNFVETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMSVCVLGDQQHCDEANANSVPCMDAEALKKMNKNKKLVKKLAKKYDAFLASESLIKQIPRLLGPGLNKAGKFPLLLTHQESMTQKIDEVKATIKFQMKKVLCLCVAVGHVGMNPEELASNVNVSINFLVSLLKKHWQNVRSLHIKSSMGPPQRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQR9</accession>
    <name>A0A1D2MQR9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.179</ecNumber>
            <ecNumber evidence="3">1.3.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-xylose 1-dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Dimeric dihydrodiol dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_11248</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16729"/>
            <dbReference type="ChEBI" id="CHEBI:10702"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18135"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="4"/>
    <dbReference type="EC" id="1.3.1.20" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000675">
        <property type="protein sequence ID" value="ODM95427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQR9"/>
    <dbReference type="STRING" id="48709.A0A1D2MQR9"/>
    <dbReference type="OMA" id="AHETGKY"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047115">
        <property type="term" value="F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="12">
        <location>
            <begin position="139"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM95427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="337" mass="37611" checksum="5A9A24A9A13E5F7F" modified="2016-11-30" version="1">MSQKSEPTRWGILGAGQISHDWSVAMSTLPPTEHKIVAVAARNAESAQKFAKLHGIPKVHKSYEDLAKDPEIDVVYIGVIHTEHLRIGKMVLDNGKHLLCEKPLCMNVKETKELVDYARKKKLFMMEAIWSRFFPAYFKLREELEKGTIGEVMQVRVEMGLAFPEDNWRRSKEVGGGTVLDMGTYTTQFTTMCFSGLKPLKIVASGHLNESGADDSSSATIIFPKGKTGTLITHSRVNLPSEALVVGTKGSMKLNFPFWAADKLETPSGVLEFPVPKTDKEFNFWNSTGLSYQCQEVRRCIQAGITESPLMSLDETILIAEIKESIRKQIGVSYPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRV4</accession>
    <name>A0A1D2MRV4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000628">
        <property type="protein sequence ID" value="ODM95736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRV4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="112" mass="12416" checksum="18DE5F1613A59BD8" modified="2016-11-30" version="1">MSKSFSIIKKGPTVPSSTMVNPKSFVSIKVLPTETHKFKDGNVAKMTHGKIRLRNEEEKQFTGSNSEYAEKDDIVDIKGNVIGVNENKEDHAAARVFTSLSYKPSKSTTKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRW8</accession>
    <name>A0A1D2MRW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reticulocyte-binding protein 2 a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000620">
        <property type="protein sequence ID" value="ODM95783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRW8"/>
    <dbReference type="OrthoDB" id="2386367at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00457">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MACPF" evidence="2">
        <location>
            <begin position="228"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="555"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1004" mass="115297" checksum="EB674B119F168776" modified="2016-11-30" version="1" fragment="single">MIRGLSNLHNRITDAKFSNVLFVFSHYCKESSRQIRRNPEPRLLQFKEVIEDYGLFPKPIFTSVIENKGKDNYLQMINGNYELPNMEYFPANLLNKFDTITKGGQDIIANAIINAAFRERENPKTFNMTETRFGLVSASHSKVAKYMSILSSATLSVGSTEVSRLLADSFETMPTQLKTQFPNALSYLQKYFNVRNFRSKNDLPQTTVAILELLEGINMKDEAVVYLLENGLKLTASTFPQKVVAGYSFNVLRDSVLPISPYKLDNNNLKMSPIGFRLPEAITCTKESNNFNLLQIVNTRDKYVRNRIESFGINMETVGSTELFTGLQRKIKEGFFVRDSSCSNNVCSFVASRYYKLFQFDLNTSAQLHPDFIKRVNNLTAFDESAYESINSWNAFFNDYGTHVVKSALGGGRIDIHVSHPTSISVDSLKNMLFKTVEFTEDPKLLITGDKIDPARVLPSGATYSLIFHGGSPTYHSSNLAAQSLEDAIKIMKNWKKSLSFHPAIYPIHYVPIHQQVAQSSSLGSQKSQIIQDATLRLFNSSLIYVAPTPDPKVLEEMARIKRENEEKLKQLAAEAKAKQEQAERERLAAIEEQKHRERDRQRREEQRRREEEELQKQLEKERQRMLKEQQEVLKRQEEEERKRQVQLTLQLLINRIQQEIRQQELQRQLDAARNRQRSSCLKQGTKILLADFTEKPVQELIIGDVLLDKDLKPTRVLGISYEFLLNQKFYGFDNQSFFFTDTHLFVGPKANVMKETLTPDQDLFQLYTTSKANLFAQNPLLKYLNVKDFDENTKFNDTLRTSLFHFDPLLHDKPVERDINVFLEPKIYPADTPIYFIQVDSPTGTYFAEGYVCRHEIPPLELWPNTIATLFSIFGTRGFKKLAQLPYSLETIYLIDGVSDNVRMRVKSVLDEEFLSGESAKHHEMNYYCKKQSLANFNLDEMIGKIFNNPTMAALAMELYGGTGSIMSKYMDNPNMPLSECQLQTLQDRIANVIGSQLEISNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS61</accession>
    <name>A0A1D2MS61_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">X-ray repair cross-complementing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_10912</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000623">
        <property type="protein sequence ID" value="ODM95762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS61"/>
    <dbReference type="STRING" id="48709.A0A1D2MS61"/>
    <dbReference type="OMA" id="DHIAICR"/>
    <dbReference type="OrthoDB" id="30826at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF4">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ku" evidence="12">
        <location>
            <begin position="301"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="551"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="557"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM95762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="588" mass="65647" checksum="CAE14CE4B31E9887" modified="2016-11-30" version="1">MGSRKPKNSPEDLCAYFVEIKEQDGMTSVMEEYVHLVGKCIEDKIFSESNDHIAICRSDTTSSISFLKADWDALRKGLKALSETKDAESGGIENPISCIDDICNAVIAQAEEDAYGEKKILYFSNLSSYVLNEKEVQDLADKLLQNEIFLSIVLPNKVGMTDIQLQNSKLIKTTFGQEKYESVSFVTNFKKAKCQILNTLSKKIPKLFSWNVPFEITPKITINVGGYVCTRQNKAAEMKKVLIKQVESDKSANGNEPSTSTALVPVGSGNTSSSNAAEKTVVIEVAKKVLEKEIIWTEKDGTVVGDEDRGKGYLFADKIVPYNDLETDESYKSGDKCMKLLVFCPVEKLNPALQCGDGTTLFYPKKDDIRSEVMFKALMQAMVKTNRAAIVRKVYRKNTRAAVGSLVPDMDRQCLVFSELSYADDVSIPQLPVLIKPEDMGDEGNDGIGEKESLIDELIAAKSLSYDFNPLEGPVDPAARNMRDMVSKKVLQNASIPSLPNESDNIEVFFQNLIVSESTLSQIRENFPLKVCKIENERLAGTNIFHKRSRENEIEDADKKPKLELKMEEASMEEDKDEDEINDLLDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS74</accession>
    <name>A0A1D2MS74_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Late histone H2B.2.2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000611">
        <property type="protein sequence ID" value="ODM95883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS74"/>
    <dbReference type="STRING" id="48709.A0A1D2MS74"/>
    <dbReference type="OrthoDB" id="7633403at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="195" mass="21564" checksum="8462C7BF14D75284" modified="2016-11-30" version="1" fragment="single">PQSYRPVTVAPSPGDPSVQEALSPQKSASCPIHFFLKSLRNQDPLGFPDSAVMALHKELLKLVDMRSTAPHSKALVQTESSYLLLSPTKPNSVLTCHQRPVDKAAKKAGKAQKKHLPKETERSFPSKAMSIMNSFVNRHFRAYCCRGFPSRSLQQEDHHHLSEIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSD4</accession>
    <name>A0A1D2MSD4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CUGBP Elav-like family member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000596">
        <property type="protein sequence ID" value="ODM96000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSD4"/>
    <dbReference type="OMA" id="WATISDI"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="225" mass="25011" checksum="6E8655FD300AF655" modified="2016-11-30" version="1">MSPHLELLRKVPSFPNYTSSLFGYPERCFPNGMSSLIVLGPPIHLYNYLPSNQCTIHASGFPDWATISDIAEIFEQFGKIYSIELSVTIDPKQRIGPAPPHCNGWALITYLSYESTQKALFAHLTRRIPGMCTPISIYKGCCSNVVLLKNLPSFLSKADILSRINSYQGLVSISFIGVSTARMIFQELDLALLFMDLVSAGGLVIEGYTCTVEPEDRDEIDDFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUZ1</accession>
    <name>A0A1D2MUZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dynein beta chain, ciliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUZ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MUZ1"/>
    <dbReference type="OMA" id="AREAWIQ"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000002">
        <property type="entry name" value="Dynein heavy chain 9, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="2">
        <location>
            <begin position="146"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="448" mass="50743" checksum="AFE71B8731F9F902" modified="2016-11-30" version="1">MRTTIRNYFAVSVTAYEDKAREAWIQEYPAQIALCGTQIWWTAEVNQAFTKLEDGYENALKDYLRKQVNQLNTLIGLLLGSLNSQERQKVMTICTIDVHSRDVVGKLIQMRIESAQAFQWQSQLRHRWDGVSGDCYANICDAELMYWYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAETTKDLGRALGMMVYVFNCSEQMDVRSIGNIYKGLAQTGAWGCFDEFNRITVEVLSVVAVQVKAIQDAIRDKKTKFVFYGEDIALNHTVGLFITMNPGYAGRSELPELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPGRPEDQVLMRALRDFNIPKIVSDDTPFLEKDAEFEASVRKATSQLNLQPEENFILKVVQLQELIDVRHSVFILGNAGQGKRRNSKCLCGNPRNFFRSHARQANMSADGPKWIILDGDIDPMWIDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVA2</accession>
    <name>A0A1D2MVA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Esterase FE4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09947</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000508">
        <property type="protein sequence ID" value="ODM96734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVA2"/>
    <dbReference type="STRING" id="48709.A0A1D2MVA2"/>
    <dbReference type="OMA" id="ISGAINW"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="5"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="485" mass="53742" checksum="D83525315CA37B97" modified="2016-11-30" version="1">MNSTGKRGFPVMVWIHGGGFTFGDGVTNYGPRYFMDEDVILVTFNYRLGVFGFLSTGDEVIPGNNGLKDQVLALRWVQTNIKAFNGDPFKVLIYGESAGGASVHFQMLTPLSNGLFSRAIAQSGSALSFWSYQGNPRENAVGIATHLNCPTTAGDSSQITSEEIRDCLKAKTAEELNEAQFTFKATWPSNLRAFIFVPVTEPVPSATSTNVPFLTETAMSLVAQGKYGSEVPFMIGATEDEGATMYAGTVLSNEEWRKELDEEWDRIAPKAVGYDVHFTPEQQKAVSDGLRQLYFGTNAIGQETAQELVDFYSDHILHGVHKAALGYAAGGKNRRTYLYQYAHRGPLSIMGLELKVHSELAKKVGHADELQQQFDVALFGGAELLPPDSAHETFSKNFVRLWTSFAYEGEPKHSWGAHSLRKWKAISRKEVDGTSPLRWYRLEENPSFIDDPYKERMTALDTILADYFAPTSAQEKASETTKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWU0</accession>
    <name>A0A1D2MWU0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000436">
        <property type="protein sequence ID" value="ODM97509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWU0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="182" mass="20461" checksum="53499CF1E4FB63A2" modified="2016-11-30" version="1">MLYEFEDRQTFLVEKESSNEEKQSIVQNKADGAGDCWNSQKDENVFTSQPLQDGHQNVSKLDKGVQVPPSPEKGKGSLRYLKRIQWENLTFSLLIVSLVLGLLVLYAVEQGNRDLAKKYAQAQETLTNKEEQIRKLHADATLARVTGDKDNVKGFMPIEWAATSVSNLIGSALRLLDMFPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWZ4</accession>
    <name>A0A1D2MWZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000454">
        <property type="protein sequence ID" value="ODM97334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWZ4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM97334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="50" mass="5969" checksum="E3B96EFBAD617EEE" modified="2016-11-30" version="1">MDPTEFEDNPNQDTNFMKNLQRRYAWTQKRMNSIFFSAMSREMSTNTGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXS2</accession>
    <name>A0A1D2MXS2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08895</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000410">
        <property type="protein sequence ID" value="ODM97792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXS2"/>
    <dbReference type="STRING" id="48709.A0A1D2MXS2"/>
    <dbReference type="OMA" id="SVIMRER"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000036">
        <property type="entry name" value="CYtochrome P450 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="497" mass="57014" checksum="4E5FB9DEE8263F74" modified="2016-11-30" version="1">MSLLLCVGLFVTAFIGTTWYIFQHYHRKHKNYPPGPIPWPLFGNVLQVDGKHIYISFMEWSKMYGKIMSVKLGFHRALVINDPKMAREMFGDLTFSGRPQAYFVTVLSGGCNGILVSEGSVWEAQRRFSLRHLRDFGFGKNIMQDLIMDNVQDIITWMRQEAGHPLPDLQRRLSLAVLNSLWTIISGQRYSQDDPHLKALLDSIQDGAVAITRHPFLIVAPWIRHILPTISGYTKFQKVVDKMIGFFRDTIEEHKHSMVDGEPRDFIDSYLKEMQKTKDTTSSFYKEAGERNLRAVVGDLFQGGSETTAITLTWSILFLMTHQDAQRKLQKEIDQVIGQSRSPVLKDRLRMPYTEAVILEISRMASVIPLGVFHSALVDTYFHDFYIPKGTWIWANQYAIHMDPYVWGDPENFHPERFLSKDGKSKRQCPGESLARDSLFLFITSIFQKFTAVPEPNTPIPDILDSDDGFFRGPKPFSVIMRERVLLSSPIIITVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ11</accession>
    <name>A0A1D2MZ11_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA-binding protein 48</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08503</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RBM48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000375">
        <property type="protein sequence ID" value="ODM98181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ11"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ11"/>
    <dbReference type="OrthoDB" id="78358at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12442">
        <property type="entry name" value="RRM_RBM48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039599">
        <property type="entry name" value="RBM48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034264">
        <property type="entry name" value="RBM48_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20957">
        <property type="entry name" value="RNA-BINDING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20957:SF0">
        <property type="entry name" value="RNA-BINDING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM98181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="196" mass="22595" checksum="C1987F732783A63E" modified="2016-11-30" version="1">MSVTPCEHHVQHEFCTTRAKYRQGKELKAVKVYTINDESQHLLIHNVPSIGLADEIMRLARKFGDTDVVQLLSDYPDVAEFTNVFYVKYRLLRDARQAKKRLDNRSFFGNLLHVCYAPEMESPAECRRKLSGRFSFVQKCFKPRREKPQFRDHVKTTSEAGTSSTDNNVGTWSNLIPQPSYHVTPVSTKNADEDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ62</accession>
    <name>A0A1D2MZ62_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000363">
        <property type="protein sequence ID" value="ODM98333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ62"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ62"/>
    <dbReference type="OMA" id="WRRGAFH"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.33.10:FF:000002">
        <property type="entry name" value="Golgi-associated plant pathogenesis-related protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="80"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="227" mass="25140" checksum="A542E0DD4FF98464" modified="2016-11-30" version="1">MGDQNRSSAASGLPQSEDQGGDDAPGWGWPSRSENQEDAGWGWPSRSEAEFQEGDAESSDQEDYANFEDSESRETRATASVRKAALDAHNAYRRRHKVPDLRGDSSLDNRAQNYANLLAKTDSMSHSKRPGNIGENLAWGGGATKEAAVKDAVKRWYDEIQFYKYSNPGYSSKTGHFTQVVWKSTKIVGIGIAYSQKKKWWVVVANYSPAGNSLNAGEFKKNVLPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N195</accession>
    <name>A0A1D2N195_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000301">
        <property type="protein sequence ID" value="ODM99077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N195"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="195" mass="23050" checksum="A61E6C3935BC55A4" modified="2016-11-30" version="1">MGAQGNLFELMEKFLKREEQVEFMICVFHEKEKICIENEEVLNNIICQLRKEGLALSEKGRVHVHRALLRSAYGKGISWLGWDKIDEIYKVYKTFSEKWKPFRVKLFSAIQVVDKEEDMWEDVVPSWEALSAMQIEDWKIALKRMNETELIILYLRTAFECLKDEWDAAKGKWEEELDQCIAQAAAFINSHQKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1U7</accession>
    <name>A0A1D2N1U7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1U7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="918" mass="105146" checksum="DF0BFC8C56FAE54F" modified="2016-11-30" version="1">MDFRVLEAIEHKERNGNPSIAAAVASINEPTLIQTQRKKARRSAVNHIELWAWGSPKRLEQYVGITKESLQNLPKFGANSATVLMGEILMDSFHELDHTSKSLAQKEGRKKALKMESTKVPSLHVLFRTPKSSQALDSEAPQISKTTNWYSTKTEGVHFDYHIKQEGERGEEWLQLSTSDDISTEVPGSDDDILPKENSNMSRSDKMMKEVALYFKILKWTGRMPFAQKKCHTFTKFYVNLACWNCRIYFATSIFMTVMGIGMLTNFIEIVNQPATSIYRKVEELEFDNYWIFGLFVMFYLWQVAVTSLVMIFQGSFHTGEFLTRWNICIDLLGYDTSTELKSITRRGLIGITVYALILICAMLVDGPFMDWNNCFGFISTLVLRDFIPKLRISKHYGWLRWLGLFVHLYTLFASRLTTQMLILYCRALETGARLYNIRLLGVLGTTSRRLKKTEGKRSTVVFKRVIPYKKLFMEHRVLTTFSRQIGRVFAVRFLTSVLMQWLIVFLTVFNVALILQGYYSSKKFKTTEIPGLQNVAIPIKYQMSLGTQGFILAVLAGFSSGSFLYTSQSLHHAGEELMKTADHIRRFSFLQCVSSMERRFILTMQNCFNPKTDFYINCGFVINRQFIFAVTTILASTSIMLCDFSIQRLLSEEIVFCNDAGQCRKAVFNPATPGVAYPERGKMLYAPNSSTIPIETPLASETSTQKRSKFEEDYMFECPGINGGTISLLRKIFYLYGDGDKVVYHSIAAQDLRKKDVWCEQDGRPFSINIAEKLALDEVNKLEAGNDTNWKHLCYRRVPSLTDNEYDDCGNRAVRLPNKITGESVWPYSKLTKITLNSKDLYYCCWTWEGYDTQCGLTKRTADTSLKAQKSYVKSICNPGGYPVEQLPLNITVLLLRSSYFSTTPFILGYFIPFSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Y6</accession>
    <name>A0A1D2N1Y6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Latex clearing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000289">
        <property type="protein sequence ID" value="ODM99293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Y6"/>
    <dbReference type="STRING" id="48709.A0A1D2N1Y6"/>
    <dbReference type="OMA" id="HDATNED"/>
    <dbReference type="OrthoDB" id="6361347at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37159">
        <property type="entry name" value="GH11867P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37159:SF1">
        <property type="entry name" value="GH11867P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="385" mass="44864" checksum="27C988751F87E2BD" modified="2016-11-30" version="1">MTVATLLKGRDVQGLRAIPDSDLIPSWTNFTLLKVGQEFAQKNAGFLGMSHLFALIFDNFLPDVKDILLATGSSNIKERAARRYTATAVQVLLWYQNSFHIPDERRILLQSVQKVRQLHFDAAFKVQLKLKDKNFLQAQRSEMKKQMELRKQSIYNDYRFWKAFIEDLKDSHVPIDKRDYPVWNYNGIPITQFTQGLTQFSFAGMVVLYHKQLGILHVTDEELRGFVHLWGVLGHMLGIHDEFNICLQADLQRTKELFEEMTEKIFVPALFHMDESSHIQLSGYLDGLEHMNDMLTPRLMVYRFLRDIVQIQPTQLYKTMPAIQKMYVAGLDGLLSDNSMTNRWLVNRNGQFFLDSNGYRFFGGNYISEDHKSRGAYYTREKLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2D3</accession>
    <name>A0A1D2N2D3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD synthase</fullName>
            <ecNumber evidence="4">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">FAD pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">FMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">Ocin01_07620</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">Involved in mitochondrial tRNA methylation. Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>FMN + ATP + H(+) = FAD + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the MoaB/Mog family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000302">
        <property type="protein sequence ID" value="ODM99065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2D3"/>
    <dbReference type="STRING" id="48709.A0A1D2N2D3"/>
    <dbReference type="OrthoDB" id="270728at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23948">
        <property type="entry name" value="FAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056596">
        <property type="entry name" value="FLAD1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293:SF9">
        <property type="entry name" value="FAD SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293">
        <property type="entry name" value="FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24102">
        <property type="entry name" value="FLAD1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="24">
        <location>
            <begin position="192"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="25">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ODM99065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="975" mass="110222" checksum="D1AFE5CF637BCCFC" modified="2016-11-30" version="1" fragment="single">RPLSIVNPLPEEDEDTMSSTPGKDPVPKPHHVARTRKPSGIISPPIRKGMMSIDRDAFDKDIKLPTIYVYEDAINPQTLQKFKKYLLKVQGLKPMTEGGFEKDSSASAAAEDGSSNNGNASSSVRKIKKVFINPELVKGCDLTHFVQHEIQPDPSIVSSVGYEAVKFSYDNWTLNQIIESVLPDDDDKVSGFSQIGHIVHLNLRDHVLPYKSLIGEVFLDKVSNAKTVVNKINTIDNKYRNFQMEVLAGDPNTVVTVRENRCEFEFDFATVYWNPRLSSEHDRLVKLFEPEEVMYDVFAGVGPFTIPAAKRKVRVLANDLNPDSFKWLQHNVTKNKVSDYVKCFNLDGRAFIQGAASADLKEQILAAKKEGSVTKKRFHFVMNLPALAVDFLDAFWGILSTLDDNTLLENTVIAVHVYCFIKDIDGFKEKAIQLVKTQLGYELPDDNILQATFVRNVAPNKEMLRVTFVLPVEVLMGSEQNKPLKRKFCEIDEDNQRLHFNVRNHPGFIRTSTYSPDQIMSLKTARCCPFSKEASSHVKKAGILIIGDEILKGQVLDTNSHFICKELYSYGVKVVRIAVISDSIDEISKEVKKFSSRYDYVITTGGIGPTHDDMTYAGVAKAFGESVTLHDDMAVMVNKWLAHRGYDQDVLKRMAELPTSAKLLFDVNRPMAGFPIVIVKNVYVFPGVPQFVEKMFPRLASIFRSELVTFHSREIYVDKDEMAITTQINKAVDKFKDTVTFGSYPVYNNLYYSTRLTMESLSADYVQKANDYLVGLMPVNTVVKFDKNAVTNSSANVYAIVDDTNHKLHQVVSKAVKVIEEALEKFELECLCICFNGGKDCTALLHLFHAVVQKKFPKTNIKIQSLYIKGDNPFEEMETFIEQTSKSYVLKIWTYDAPIKNGLTTALMEHKQLKGVLMGTRRSDPSGEKLGYFQMTDAGWPQIMRISPMLDWSFSDVWTFLRSLTLPYCPLYDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2K8</accession>
    <name>A0A1D2N2K8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA-binding protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07176</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000275">
        <property type="protein sequence ID" value="ODM99502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2K8"/>
    <dbReference type="STRING" id="48709.A0A1D2N2K8"/>
    <dbReference type="OMA" id="LEWVTES"/>
    <dbReference type="OrthoDB" id="443401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000330">
        <property type="entry name" value="RNA-binding motif protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14605">
        <property type="entry name" value="Nup35_RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="46"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="466"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="259"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="505"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="519" mass="59204" checksum="DB9385EEAF3403DE" modified="2016-11-30" version="1">MRGPHPQMPPMQMHPMRGVHGMRGRGRGGFDHGRLGAKPPRNYTNCSLEVRKIPREQNTIMDLNSHFIRFGKIINIQINYDNDPEAALVTFSSPAEAQLAYRSTEAVLNNRFIRVFWHNKEKENEEEAEMSNPPRIPIKDRLGGHQQEPVDDRRHEHEKILISGNNLTKTVYNNALLAKKMETPQEKLQAVEAIRKSQELLAAQENLKKLQEQKKQEVLKMSNDLRKRKQVMMEEQIEQQKKLIGKFEHSKDKMKPEEKESLLNLIKSLQESVEKLKRDLDESNPNISKQPGFQGLKSKEEAQKEMLDAELDLYNKEQQGGDTVDLQKKVLELRARAKSMGLIGGTVRGGAVAEAHLGEPDEVDLGVGEELFEGRLRALRSVDRRPTKLRVTGCPASRLPDLLNHFSVFGLIRDYESDSTVPVMIVEYESRKSAEVAMTNGQVFEDNKLTLEWVTESNPESKLLQAENSNNGETSNHDDLDTSASLDEDEEELGDILNSEIMLTGEDEDEDDEDRSWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2S3</accession>
    <name>A0A1D2N2S3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000272">
        <property type="protein sequence ID" value="ODM99531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2S3"/>
    <dbReference type="STRING" id="48709.A0A1D2N2S3"/>
    <dbReference type="OMA" id="FWCLEHD"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904941" description="peptide-methionine (S)-S-oxide reductase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="6">
        <location>
            <begin position="32"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="203" mass="22758" checksum="9D38CE777936F460" modified="2016-11-30" version="1">MQVQLIFVLCLVFTVHSETECEMAAPAGRQLATVAGGCFWCIEAVYNMHKGVHSAVSGYMGGKKDKPTYEEVCKGTTGHAEVVQVTFDPQVVSYAELLEVFWKVHDPTTLNRQGNDVGTQYRSAIYYHDDEQKRIAEASKAAATEAQLYSGTIVTEITKASKFFPAEAYHQEYYKNNPNQGYCHAVVGPKVKKFKELFREKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N367</accession>
    <name>A0A1D2N367_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000263">
        <property type="protein sequence ID" value="ODM99671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N367"/>
    <dbReference type="OrthoDB" id="10659570at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="266" mass="27965" checksum="6AAE5F057F526B9C" modified="2016-11-30" version="1">MGSIVVSTAEDSLLTIFTIDYKNTSVLLHSVHLSTQLRELIETRSKRSPKGGKGSTFKKVAVGAVAGAATYHVASQASKGFKGSFQTTEAPKKYKRVYACFSRVGGQCALNYNNWQSVDSSSSSSSTTTTSTTTTEAATTIPTSTVASENVTSSTNVTEPTTTTSTTTTAAPTAAAQTQPLDISKIPKCIEHAVCKHGSPSQGNGTSTFLQKVDFDPRLGVCECEAGYERTSKDICVKVKRSGAAEKTVAGAVIIAALAFNKMFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3E0</accession>
    <name>A0A1D2N3E0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000258">
        <property type="protein sequence ID" value="ODM99741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3E0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904972" description="Protein quiver" evidence="2">
        <location>
            <begin position="22"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17914" checksum="85FBB053A1399E9F" modified="2016-11-30" version="1">MCLLTLTLTVSILLAPCPTNALQCWQCSVVGDLGWVSDCETGKHGTSIECIGSNSYCIIARVTTSTHKMFIKDCGNAIGDAQIWCESNYTSGLDAHMETCFCNGTNNCNRFEHNIKTTGQAYSTFMSSSPEGNAYNDGTGLSPMTITLAVMILLGILWKLMWSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Q4</accession>
    <name>A0A1D2N3Q4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein XRP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06792</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000249">
        <property type="protein sequence ID" value="ODM99893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Q4"/>
    <dbReference type="STRING" id="48709.A0A1D2N3Q4"/>
    <dbReference type="OMA" id="NDVTPNW"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990075">
        <property type="term" value="C:periciliary membrane compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039093">
        <property type="entry name" value="XRP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15440:SF0">
        <property type="entry name" value="PROTEIN XRP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15440">
        <property type="entry name" value="XRP2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="282" mass="32966" checksum="D8B35FE171ACC88B" modified="2016-11-30" version="1">MTCRDKRRKLDPSEYTFADLVSSQRLKRPGELNGQQFIIRNCINSKIYLLDHVSTMTIDDCNDCIFVTGPVSGSIFLRDSKNCTLMCASSQLRLRDCQNIYLYTACESDPIIEASTDVIIGPYFLSYKGIKDHFTSAKLSNFKATRWAQIYDFTPNDVTPNWGRYDREKQDPHKFICPPMPICEFEDLEISLEASKSFVPVTRYTDEEDLLHRQRRHEIIFDLQQDDDFKTVMTYYREKFTTPNDLNTDRIRGGPRHFLGNVEMRGTQVIFIYYDEEDESVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3W8</accession>
    <name>A0A1D2N3W8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycine receptor subunit beta-type 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06704</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000242">
        <property type="protein sequence ID" value="ODM99977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3W8"/>
    <dbReference type="STRING" id="48709.A0A1D2N3W8"/>
    <dbReference type="OrthoDB" id="6667051at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19049">
        <property type="entry name" value="LGIC_TM_anion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="3">
        <location>
            <begin position="24"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="30181" checksum="7D773FE4D5E62B3E" modified="2016-11-30" version="1">MRSYSGIRFTILLRRKLSYHLIQTYLPSTLFIIVSWLSFLVPPESVPGRMALCMTTLLTLTAMFSAVRQNTPNVSYVKALDIWMVVCIIFVFLTLVEYTVLLKLKSKKPKPRPISEQTELAPVAQPQQPPARWTIPALQYSSDVSNFKFRGCKNVETVVNENGSTGEMRHRENGDSVGAGGDNGNNVTSPPPPPASPTPPPQPPPPAAPLHPSEKPLNKYELAAKKIEKFTSAVIPTLFVIFNFIYWPWLIESADYYHQEKSTTIFKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N438</accession>
    <name>A0A1D2N438_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ketohexokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000238">
        <property type="protein sequence ID" value="ODN00030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N438"/>
    <dbReference type="STRING" id="48709.A0A1D2N438"/>
    <dbReference type="OMA" id="CNLATRK"/>
    <dbReference type="OrthoDB" id="204058at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="21"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="293" mass="32818" checksum="C7930D27D52D55E0" modified="2016-11-30" version="1">MRRANLGERWKCLQQCHRFGLHGCPVECLGTLADDKLLKFLQEDMDIVGIKYDNCPIIQCGNGPMSVVVCSQATGSRTIIHAKGNLPELTLENIRKLNLRNYTWMQFEGRNEFELPRIMQFVREYNDKTCTRTNLSDVPNYKKATLPVSLEVELHIENLDNLLPLADVVLVGKDFAKVQGARDAIEAARIMSQKVLPGTVVICPWGDQGASYCVTSEDPNKTEITTQEAYVCDNVVDSLGAGDTFNATVIYCLNKGYDVGTSVNYACRVASMKLKVRGLKGLRDMLKNERIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N476</accession>
    <name>A0A1D2N476_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Integrin alpha-PS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_06611</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the integrin alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000235">
        <property type="protein sequence ID" value="ODN00073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N476"/>
    <dbReference type="STRING" id="48709.A0A1D2N476"/>
    <dbReference type="OMA" id="HTYELIN"/>
    <dbReference type="OrthoDB" id="5317514at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033627">
        <property type="term" value="P:cell adhesion mediated by integrin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007157">
        <property type="term" value="P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.930">
        <property type="entry name" value="Bicelle-embedded integrin alpha(iib) transmembrane segment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1460">
        <property type="entry name" value="Integrin domains. Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1510">
        <property type="entry name" value="ntegrin, alpha v. Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1530">
        <property type="entry name" value="ntegrin, alpha v. Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000413">
        <property type="entry name" value="Integrin_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018184">
        <property type="entry name" value="Integrin_alpha_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013649">
        <property type="entry name" value="Integrin_alpha_Ig-like_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048285">
        <property type="entry name" value="Integrin_alpha_Ig-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048286">
        <property type="entry name" value="Integrin_alpha_Ig-like_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032695">
        <property type="entry name" value="Integrin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220">
        <property type="entry name" value="INTEGRIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220:SF122">
        <property type="entry name" value="INTEGRIN ALPHA-PS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08441">
        <property type="entry name" value="Integrin_A_Ig_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20805">
        <property type="entry name" value="Integrin_A_Ig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20806">
        <property type="entry name" value="Integrin_A_Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01185">
        <property type="entry name" value="INTEGRINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69179">
        <property type="entry name" value="Integrin domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00242">
        <property type="entry name" value="INTEGRIN_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13 17" id="KW-0401">Integrin</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="951"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="12">
        <location>
            <begin position="241"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="12">
        <location>
            <begin position="301"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="12">
        <location>
            <begin position="363"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha first immunoglubulin-like" evidence="14">
        <location>
            <begin position="410"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha second immunoglobulin-like" evidence="15">
        <location>
            <begin position="580"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha third immunoglobulin-like" evidence="16">
        <location>
            <begin position="732"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN00073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="994" mass="110778" checksum="40BC61F6ADD823F4" modified="2016-11-30" version="1">MIFVSFVDYRILVGAPLGQNLQPQTNRSGALYKCPISSYEGDCEQVITDGKRVMEQNELSPPLDDELKDGQWMGVNVRSQGPGRKVMVCAHRYVNQGKDFRWGLGLCHFLTQYLEYDQTLEPCRNKVRRALEDYGFCQAGTSADILEDDTALMGAPGAYTCRGMVFGISVSDDYLNKDRNHYHTPLLENSPIDKYSYLGMSVSGGRFFGDHYSYVAGAPKAALGSGQVFFFTKGGDQGSLQVEGFLTGEGFAFSYGYELATLDINGDNKTDLVVGAPFYMDSKQAGGAAYVYINDDGFRPDHPYVRLTGTRESRFGLALSSAGDLNRDGFDDLAVGAPYSFEGTGAVYIYLGSKDGIIREPSQVIEGREYYPDMLTFGYSLSGGADLDGNNYPDLLVGAYDSDAVVLLRARPIIDVVTNVYGNLSNIDPNGHGCSEFPTSNQTCFSFIACFEITGITQVRASSLRVEYRIEAETFVEGKKFSRVAFYNGRRDRPQLVNQTVTIRRSGAASNKYCSNETVFLKEGTKDIQSPIAFKLTYTLIQREPVYIPNAATLPNIQNYPILNQQEASKVFLANFEKDCGENDHCESDLYVNAVPELEETDDSGHYLLVLGRDTVFVLNISLANFGEPAYEAALYVSHPKSMSYIGQDAELQKKGLGCTPFNASLVSCPLGNPYKRHADFRYLRLRFDAGNLKDIETKLEFEVWANSTSIDDDEQNNHKTVTATVIKMAELSIAGTGEPEKLFYVYGGNVIGESAIKSLAEIGPRVTHQYEVWNAGPWKASYFNVDIWWPHQVENGKSQGKWLLYPEGPPVLDGDGQCFLPNDVTDILHLRTKRETETIVASQKERGPDGKFKTYVEMNCVRGSAKCFRIECVIRNLLPRESAVIKIHSRLWNATLVEDYPTVDEVRIRSKAQIRISDEIRQDPGNDVAQALTTCFPDLKLKVELEGIAWWIYAVSILVGIIVLALIVYCLYKTGFFKRRRPEPTHTARVSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4D4</accession>
    <name>A0A1D2N4D4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="11">PARP</shortName>
            <ecNumber evidence="11">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_06597</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H(+).</text>
            <dbReference type="EC" id="2.4.2.30"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ARTD/PARP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000234">
        <property type="protein sequence ID" value="ODN00092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4D4"/>
    <dbReference type="STRING" id="48709.A0A1D2N4D4"/>
    <dbReference type="OMA" id="SEECHET"/>
    <dbReference type="OrthoDB" id="429950at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990404">
        <property type="term" value="F:NAD+-protein mono-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070212">
        <property type="term" value="P:protein poly-ADP-ribosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01437">
        <property type="entry name" value="parp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.228.10:FF:000002">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF112">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0013">ADP-ribosylation</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PARP catalytic" evidence="13">
        <location>
            <begin position="24"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN00092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="26715" checksum="A2D6E45B54084878" modified="2016-11-30" version="1">MLDNLMEIEIAYELLAQGDKGESGSIDSYYNTLNAEIDILEAHSEEFKIIKKYLMNTHVFKVIRKGENKRYRPFKDLHNRRLLWHGSRITNFAGIVSQGLRIAGGPVSGYMFGKGIYFADMVSKSANYCNTSRDNPTGLLLLCEVALGDMHELKQAKDTISKPPKPNHSVKGLGQTEPDPKETHTFSDGVMVPYGKPVTSKAAQNSALLYNEYIVYDIAQVNIKYLLRVNFKYGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4E4</accession>
    <name>A0A1D2N4E4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA cleavage complex 2 protein Pcf11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000230">
        <property type="protein sequence ID" value="ODN00139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4E4"/>
    <dbReference type="STRING" id="48709.A0A1D2N4E4"/>
    <dbReference type="OrthoDB" id="343582at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16982">
        <property type="entry name" value="CID_Pcf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045154">
        <property type="entry name" value="PCF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047415">
        <property type="entry name" value="Pcf11_CID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048830">
        <property type="entry name" value="PCF11_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921:SF3">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15921">
        <property type="entry name" value="PRE-MRNA CLEAVAGE COMPLEX II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20845">
        <property type="entry name" value="Pcf11_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="372" mass="41906" checksum="19989717EDFD6A5B" modified="2016-11-30" version="1" fragment="single">MGEDIVTKYSSSLAELKMNSKPLINLLTMMAEDYIRHAPSIVQVIERHLTTVRPEIKLPVLYLIDSIIKNVKKDYVELFTQNIVSTFCGVFEKVDEKTRGLLWKLRGTWSDYFPTKKLYAIDVRCHQLDPKWPIMAQAPSSASIHVNPRFLNRGKAAAALINPEHIIAQTTASAAVAPVTAPDDSVMEVQMRAQLLAKQKELLELQTRKVELELLQTKLQMEEKARRQKEEETAKQIDMAVKQEQVLVGMAELAKNKTERIQQKLSSMHMPSSSVASASSSIKGSPSSSKGRASSSDAESHSTFPSKLTKSSNETSASSVDNSPSKKSKSSRDRDRRDRGKNDKSKETRHELKDKESRHRHRDKDRHADSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5A1</accession>
    <name>A0A1D2N5A1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAS-associated factor 2-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000207">
        <property type="protein sequence ID" value="ODN00434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5A1"/>
    <dbReference type="STRING" id="48709.A0A1D2N5A1"/>
    <dbReference type="OrthoDB" id="1026733at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="257" mass="29044" checksum="2C430DF1BB7839E9" modified="2016-11-30" version="1">MMGAGNGKPSVSQPSPNRPITRAYRRMLSQELEPQGGGQQREENGDRKRPTEDGRGDSDRPKPIKKGKYDEKNEEEVIIDDDSEYSDSEYSDAESPINQRRPAPRETPSTTRSIVAEQNHAYNESLRADKEKERVKQEKAKEKEALNDAKEKILRLKKEAEESLPVEGSTGEEGVFPLVLRLPTGKSVRRNFRATDSIHTLRQFAFSQDATPVRFEIVKYPNEVLPVGKNGDGSTLTLKDVGITKREALHVRMQERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5R9</accession>
    <name>A0A1D2N5R9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000196">
        <property type="protein sequence ID" value="ODN00630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5R9"/>
    <dbReference type="STRING" id="48709.A0A1D2N5R9"/>
    <dbReference type="OMA" id="KKKCRAF"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000003">
        <property type="entry name" value="Dna-directed rna polymerases i and iii subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="61"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="38759" checksum="E24D20EFA39F0345" modified="2016-11-30" version="1">MSGGMDNMLSSRKLAVMGKHEVINASGSLCPGSYFGYDDAWTLDKFKQRTQIKIIRMAGNEMEFDLIGVEPSLANAFRRILLAEVPSMAFEKVFLQNNTSIIPDEVLAHRLGLIPLKADPRLFEYRPKDESSPSEQDTLKFELKVKCTWNPNRPADSSEPDEMYQNHKVYSGNLRWIPIGSQSRMYTAKDVGPVEPDILIAKLRPGHEIDLTMDAVKGIGSDHAKFSPVATAFYRLLPQITLHKEVVGEAAERLQKCFSPGVIKLVEKKGRRIAAVHDARYDSCSRNVLRYDDLADCVSLGRVKDHFIFSIESVGAVSPPSLFIESIRALKAKCRKFLREIEKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5X7</accession>
    <name>A0A1D2N5X7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paired box protein Pax-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000196">
        <property type="protein sequence ID" value="ODN00631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5X7"/>
    <dbReference type="STRING" id="48709.A0A1D2N5X7"/>
    <dbReference type="OrthoDB" id="3225452at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="316" mass="34588" checksum="FBCF08042B12C6B2" modified="2016-11-30" version="1" fragment="single">MNHPQLQQFMEQRKPVAVECFAEWKAPLPNAVRLSPIVELAQLGIRPLLIFLANFVHETGSILPGAIGEVSLVSLQKVAVLLKNSESIQYVSYQIRYQFSLCMKRIPVYSLGEIRDRLSRQTGVCDKYNVPSVVSQHTWAAIAIITTTIITALLLLHIMEAANRIHPVSSTTHPPHPYDTKHPHPHHHHHHHHHHAAVVAAAAAVAANPLYNSIYPPYSSYGAHHHHHAAVSQVGWGHDKLAVTNNESNGFNGFNGLENWCGGCSTGLSLGANPSSCLHVMRTNGWATGAPDLSSAATNMGFRPTQPLGSAHHPHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N690</accession>
    <name>A0A1D2N690_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock factor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05926</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000188">
        <property type="protein sequence ID" value="ODN00742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N690"/>
    <dbReference type="STRING" id="48709.A0A1D2N690"/>
    <dbReference type="OMA" id="MEFAHPF"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="244"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="331"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="655"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="657"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN00742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="674" mass="73577" checksum="51CA7E50BBBE79FB" modified="2016-11-30" version="1">MHTLVEVPVGGNGGTHVPAFLAKLWKIVDDPSTNDLICWSDMGNSFTIKNQAKFARDLLPLYYKHNNMASFVRQLNMYGFHKVVSVEQGGLRVDKDEMEFAHPFFLKGQEASLELIKRKIPASKHEESRIRPDSLNKVLLDVRQMKGRQETMDNKLLTMKRENEALWRELASLRQKHAKQTQIVSKLLQFLVGMMSQQTPRLAFKRRMPLMLNDKDGVKQKLSRTDANEPTGPVIHDVTELLESDDSGEDVGDQEYTITSGGTPEAKSIDSSPLSIPSKSPYSEAVVGDNLCPTSPEMLFSMDPSSINPTVASPGPIVAQLQQAVHNVQHKQQQVKPKGKTFTRKMPAVGPSMPSVKLENNVGFPKSTTNVPQTTNNVPTTLYFSAPGVAEPVQVVLSIPNQTSTTTVPTTSNVSIPTPVVTAPATTSSTSGKALNVPQQPPLNVPMNKPMSMHGNGMDAVGRNQTLNPRIFLKANGNVAQEDLDGHLDDVEVGLNHLKDLFKGDEYQVDSDTLIGVSNSRPFNFGAIDPETYAQLFTGSPPFDNTENHAEQSQQLQMAAGGGGGGGEVGHLEGQELVTYNPSLFELAEDDSNFFDESSNIFLDDELESMLTTDRNSLKRQEGQNRGVGQLSFSGVNLNNSFVSGLNTPVVCEPIIGQSSSIPGTSGASKRKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N881</accession>
    <name>A0A1D2N881_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase Q</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="21">Plasma glutamate carboxypeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_05526</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="20">Homodimer. The monomeric form is inactive while the homodimer is active.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000168">
        <property type="protein sequence ID" value="ODN01176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N881"/>
    <dbReference type="STRING" id="48709.A0A1D2N881"/>
    <dbReference type="OMA" id="WVRGSEQ"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03883">
        <property type="entry name" value="M28_Pgcp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000036">
        <property type="entry name" value="Carboxypeptidase Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.30:FF:000009">
        <property type="entry name" value="Carboxypeptidase Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039866">
        <property type="entry name" value="CPQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12053:SF3">
        <property type="entry name" value="CARBOXYPEPTIDASE Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12053">
        <property type="entry name" value="PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 24" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="18" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-0458">Lysosome</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="11 22" id="KW-0732">Signal</keyword>
    <keyword evidence="14" id="KW-0862">Zinc</keyword>
    <keyword evidence="17" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905190" description="Carboxypeptidase Q" evidence="22">
        <location>
            <begin position="19"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="23">
        <location>
            <begin position="313"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00025833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00033328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODN01176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="516" mass="56632" checksum="E750D2A6A1919FAE" modified="2016-11-30" version="1">MFVHKLLLIICHISAIFGYPQLVNPKLSKNHANMVLQFANTPEEDLGFDSSENSVVEVDSITVDPPSLQDPCQNLSQDIISEIAGYKDVANRIFQTVLSGSFKGRTYNELSYFVDKFGSRVAGSENLEHAIDYMLDKMKQDELDNVHGEKVQIPHWVRGEETAALISPRKKDLSILGLGYTVGTPPGGITAPVLVVSGFDELQQRAEEAKGKIIVFNEAYESYGKTVKYRGTGANEAAKVGALATLIRSVTPFSIDSPHTGMLDYVDKVTHIPSACISIEDAQLLYRLQKMGEKLVIKLVMNDTNLEPKTSRNSVAEIVGREKPDNVVVISGHIDSWDVGQGAMDDGGGAFISVEALALLRFLKLQPRRTLRTILWTSEEFGLIGAQQYVQRHSSELEKFNAVFESDIGTFKPLGLDFAGSSAAGCIVKEVVKLLAPLNATTFRASSDVGSDIGYFLDKGVPGFSLNNANEKYFWFHHSQGDTMTVENADELDMCTAVWAVSSYVIADLSVDLPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8D3</accession>
    <name>A0A1D2N8D3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative tRNA (Guanine(10)-N2)-dimethyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000165">
        <property type="protein sequence ID" value="ODN01236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8D3"/>
    <dbReference type="STRING" id="48709.A0A1D2N8D3"/>
    <dbReference type="OMA" id="VEWIAGF"/>
    <dbReference type="OrthoDB" id="8250698at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="2">
        <location>
            <begin position="164"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="465" mass="52861" checksum="EFF789710AB121EB" modified="2016-11-30" version="1">MGAEEKNQPETPQNVGAVETAEATVMPPEEPPKMEDIVTADVLQDIIKGYNKPDMKLVSFDAQPGSNIGDNYMSIMYALEIQLQNEKSGEKETLHVMLKTIPRNVFRIEMINEMKAFQKEAIIYQQVFPMLVETQKEKEVPSSELFTAWPICYATHVDGATDYLAMENLKIAGFQMGSRTAGLDFNHCNLVLRNLAKYHAISFAKFNGDRQKILEYLPVLNTSMFDPESKISTMQQQFMEQSFQNMAKNLRGEGYTEAAIRLEKMAASQFSVTLNSLIQENIEYAVVTHGDCWVNNILFNYDGDDSNKSAVPKAVKFLDFQLCQATSRLIDIYYFLMTSAKLDTINEREQDLLMAYYTEFTSFAERLGINTHERGLTYENFLKEVDHFRLYGVFMGLLLAPMLAANAEDIPDMEAMTEEDFSGKSEENSKKFIEDIYKGKANKKVECLVMKHLPKCNQGAAYCSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8S1</accession>
    <name>A0A1D2N8S1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 20">Phosphatidate cytidylyltransferase, mitochondrial</fullName>
            <ecNumber evidence="6 20">2.7.7.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 20">CDP-diacylglycerol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19 20">Mitochondrial translocator assembly and maintenance protein 41 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_05014</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 20">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Mitochondrion inner membrane</location>
            <topology evidence="2 20">Peripheral membrane protein</topology>
            <orientation evidence="2 20">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 20">Belongs to the TAM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 20"/>
    <dbReference type="EMBL" id="LJIJ01000144">
        <property type="protein sequence ID" value="ODN01670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8S1"/>
    <dbReference type="STRING" id="48709.A0A1D2N8S1"/>
    <dbReference type="OMA" id="HAENMHR"/>
    <dbReference type="OrthoDB" id="341477at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015222">
        <property type="entry name" value="Tam41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619:SF0">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09139">
        <property type="entry name" value="Tam41_Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028840">
        <property type="entry name" value="Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 20" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13 20" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 20" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 20" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11 20" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10 20 21" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16 20" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="17 20" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20 21" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR028840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODN01670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="41806" checksum="7FF1CE2058364A7D" modified="2016-11-30" version="1">MAIVADGALKEILRHFPIKQCSYVFAYGSAVFLQKDQTPGKMLDLVFVVDDPIKWHTENLTMNRNHYSGLRRFGPKAITRIQERMACGVYYNPYCNVDNLTIKYGVISSASLEDDLRLWKHLYIAGRLHKPVLTLQSPTPALEEAMRKNHQTALRAVLLQEGIQMSKFDLYHGITELSYLGDTRMRFAENPKKTRNIVQPLINEFDRLYMPLVNETGIAKYTENGLVIQDTSPSVRFKLLMSLPNPLQISLAQQHCRDPRFFDIEEIMAELSYLPYLRLYIRTAISDVVRGASLLQTFQGILTAGVFKSIKYGLDKLKKRVQRKPSPPQELLPPPDVQQSEDKIRLIFQLKSPPFKKRGRMMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA18</accession>
    <name>A0A1D2NA18_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine protease</fullName>
            <ecNumber evidence="11">3.4.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_04585</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA18"/>
    <dbReference type="STRING" id="48709.A0A1D2NA18"/>
    <dbReference type="OMA" id="QCIANID"/>
    <dbReference type="OrthoDB" id="2960936at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019786">
        <property type="term" value="F:protein-phosphatidylethanolamide deconjugating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035973">
        <property type="term" value="P:aggrephagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF49">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11 15" id="KW-0645">Protease</keyword>
    <keyword evidence="8 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="14">
        <location>
            <begin position="184"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="531"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="551"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN02098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="577" mass="63382" checksum="AC20EAD8F171D2D2" modified="2016-11-30" version="1">MKSCTEGKKTDIAITKTNECSRSTEKILNEEKQVNQHIGKVICLEISFLVEYSILLFAYTVVCFLCWLVESVLIPFPRTLASNSLVRRLSNWWKVTDGLESSYSRLLWFRMQHPGYFSSHQNSTTSNSSLRHAEQVLDRVKKGIRLKMDKVLDAYLTGGDSDFPTCESPVWIFGRSYSVNYDIEELRRSVSSCMWITYRKNFSSIGGTNLTSDKGWGCMIRAGQMLVAKALLLRHLNQDWHWDSECRDHLYLQIVSLLEDTKVAPLSLHQIAQSGASLGKPIGSWLGPNTVAQALKKILSSEYVSLDIALHIAMDSTVVKSEIKKACFTTSGHALPISVPPAYIVSTPRPDAKWKPLLLVVPLRLGLSDLNEAYVPGIKAAFEIPQNIGIIGGRPNHALYFIGYAANEVLYLDPHTVQPTVFVSTKLTEVEKAADETYHIHKPGRMSFSAMDPSIAVCFFCKTEADFDAVCSKLGERFLVTPLPLFEICERRPHDWGSASFVSSSSSSVKTSSKSASKSSSAALGFTTLSLGSSSGGSKSTAGGGHSITRSAGGSPSSSVSGRSKSDVDDEDFEILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAW0</accession>
    <name>A0A1D2NAW0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAW0"/>
    <dbReference type="STRING" id="48709.A0A1D2NAW0"/>
    <dbReference type="OMA" id="AGHLICI"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF2">
        <property type="entry name" value="FMRFAMIDE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="81"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="393" mass="44811" checksum="95F1124EB9DE0816" modified="2016-11-30" version="1">MGDNKTFRLPILFCALIDFPKNTTECTTQKPESGDLVCFTCPIVGRFLFGEPVEAFRSAGHLICIHLWVSVLIVGTFGAVSNCLIIAIMKRHKEKRTFDFLLMVLASFDLLTCMMSLISTCALMSYYEDWDRGPETLFLFVFPFMIGLLGRSASSYITVLITIERYLIIAHPMKSVHWFTATKTKIMTIGASILALLINIPRLTSMKISKNDAWKSMPSLQTREYIVESTALEEFWYRNLKSIHYQIDMWAPFPLLITFNILLYLKIKTFAKNRQGLSKTQRRDIRAARMFVPVVIVLFICNIVPMSGYVVMHFGRVIHREVIFLLTFATVVNAAANLPIYYARGPSFRQEIKAELPLLCGWIKSVDNDPKARDLSMTDRNTNGTGNSTNLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBI6</accession>
    <name>A0A1D2NBI6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 4H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04062</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000103">
        <property type="protein sequence ID" value="ODN02620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBI6"/>
    <dbReference type="STRING" id="48709.A0A1D2NBI6"/>
    <dbReference type="OMA" id="ECKGGWD"/>
    <dbReference type="OrthoDB" id="48651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF11">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="22"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="106"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="284" mass="30615" checksum="64177C4702F491DC" modified="2016-11-30" version="1" fragment="single">EYGGNRYRNFGQTDPSSRQPPFVAYVGNLPRGVVQGDIDKLFGDLKTRSIRLVYDKETERFKGFCYVEFDEFETLEKALQYDGSVIDGVPIKVDIAEGRKNDRGGQRGGRGGGPMNRGGSGHQTGGGNARVGQGGYGGRGNGGGRDGGRDGGRDGGREGGRDGQGRDGGRGGGNSYCGGREGYNADRVQRPYNADARGYSSRPRRDSERSKTSEEFKEPTPEELAARPKLKLLPRTVADPVNAIASTKQALDIFGGAKPREENLKGKPKEIKNHEGIVERDTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBS0</accession>
    <name>A0A1D2NBS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBS0"/>
    <dbReference type="OrthoDB" id="10258692at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="35032" checksum="DED604D8915657AD" modified="2016-11-30" version="1">MCRVAWSSRVRGKEVYGREVQDSTLTAASLIDAIITHQINQPSPNDRSSPAPTNRTGDRLFASFQRSPASQQSGGGHGNPQQNPHNLSIPNQVHGHGPPQHEEKVVVNDGRMNHKMPPARYITGIADVNVGLFKINRRSERVDPPMKSGPSMGPGGVPSFGRREGISLDYFNNLIMEKMRNENNEEMKSEDGHERKHDPNSGPSVPQMNLPGGSASHVHGHNPAAHGHPSHFGGLAGRIAAAARDDMRSNSDSQRGGDGQHFQLKIEKMDDEPSKGGDSDSPASMVIDESADMKDPKSQQSHNDSSATATSQPNYEPLTDEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBY6</accession>
    <name>A0A1D2NBY6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_03915</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NBY6"/>
    <dbReference type="OMA" id="ITQHAKH"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18021">
        <property type="entry name" value="DEXHc_Brr2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000002">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000368">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000004">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000254">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000013">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="53"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="701"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1503" mass="171386" checksum="0FB54AE9BC2D56A3" modified="2016-11-30" version="1">MLFDRLTGVTQEGEIRIVGLSATLPNYKDVACFLQVDLATGLFFFDNSFRPVPLEQQYIGITEKKALKRYQLTNEIVYEKVMEHAGKNQVLIFVHSRKETGKSARALRDMCLEKDTLGHFLREGSASMEVLRKEAEDVKNPELKDLLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWVELGALDVLQMLGRAGRPQYDTKGEGILITNHSELRYYLSLLNQQLPIESQLVAKLPDLLNAEVVNGSIQSVKDAVEWLEYTYLYVRSKRAPQTYSVDDDDKTLLVHRANLIHTAALKLDKSGLVRYDRSSGSFIPTELGRIASHYYITCETVQTYNQLLKPHLSEIELLRVFSLSSEFKNLGVREEEKLELQKLMERVPIPIKESVEESSAKISILLQAYISQLKLEGFALMADMVYVTQSAGRLIRAIYEIVLSRGWAQVADKTLALAKMIDRRMWQSMCPLRQFKKIPEEVIRMIEKKSIAFDRLFDLNPLEIGEMIRHPKLGKSIHKFIHQLPKVDLSCTIQPVTRSTLKVELVITPDFEWDEKVHGGSVAFWIMVEDVDSEVVLHHEHFVLKQKFKNDEHIVKFYVPIFEPLPPQYFIRVVSDRWIGSETVLPVSFRHLILPEKNPPPTELLDLQPLPISALRNGAFEVLYKEFIQFNPIQTQVFNAVYNSDENAFIGAPPGSGKTMIAEFAIMRMINTIGRERPGEEHCVYVTPKEELAESLYAEWNSKFSKLGRKVIMLTGETGTDLKLLAKGNIIISTPEKWDVLSRRWKQRKNVQNVNLFIVDDLQLIGGEEGPVMEIVCSRMRYIASQTEKPIRIIALSTSLSNARDISQWLGCPPTHTFNFHPSVRPLPMELHIQGYNISHNASRLAAMSKPIYNAITKLSPDKPVMIFVPSRKQARLTAVDIINYSEVEGKHGRFLLLNESELQGVFEKVQDETLRGLLTQGVAYLHDGTSPTDRHIVSSLFKSGAIQIVVATRNMCWSISFHSHLVIIMDTQDYNGKIHAYEDYAVTDVLRMLGRANRPLEDDDSKCVLMCQTSKKEFFKKFLNDPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGVTHRHLSDHLSELVENTLNDLEQSKCISVEEEMDTSPLNLGMIAAYYYINYTTIELFSMSLTAKTKLRGLLDIVSSSYEYSSLPIRHHEENVLQSLATKLPNKPASASSQIKFTDPNVKANILLQAHLCRIQLSAELQQDTEYVLSKAIRLIQACVDVLSSNGWLSPAVAAMEFAQMSTQAMWAKDSYLKQIPHFGSDLIKRCTEHKIETVFDLMDLEDEDRSKLLDGLSPVQISDIARFCNRYPNIELTYEVESKDKIRSGSNVNVSVQLEREDEIVGPVIAPFFPQKREEGWWVVIGDPKTKLPVVHKTLDFAAESQGEYTYTLYYMSDAYMGCDQEYKFNINVRGGRERKKDASDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCE9</accession>
    <name>A0A1D2NCE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vascular endothelial growth factor receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_03764</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000092">
        <property type="protein sequence ID" value="ODN02922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCE9"/>
    <dbReference type="STRING" id="48709.A0A1D2NCE9"/>
    <dbReference type="OMA" id="HISTWIY"/>
    <dbReference type="OrthoDB" id="3256376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000554">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001916">
        <property type="entry name" value="Glyco_hydro_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019799">
        <property type="entry name" value="Glyco_hydro_22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF602">
        <property type="entry name" value="PROTEIN VER-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00062">
        <property type="entry name" value="Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00263">
        <property type="entry name" value="LYZ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00128">
        <property type="entry name" value="GLYCOSYL_HYDROL_F22_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51348">
        <property type="entry name" value="GLYCOSYL_HYDROL_F22_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="208"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="524" mass="59794" checksum="4D2B9D1988EED972" modified="2016-11-30" version="1">MGICMAEQLSKLNSSKLSVTKMVHENTEEEFCKRYTLGLFQISNGWCTTDDDKEFGDCKRNGCQLDCRKLLDDDITDDVECIKRISEIEGLVSWRPTAVSTCRGERFNETLCLTLGKSQNRKLTSIPLWAAFLIGGICCLVVFGLTYYYFKYCRGKSPMLSAAEIKEFKYGRISSDSRTSRTSKLPQESYTNEAYDNQHEVFPSEFDIDHTHCLGSGAYGIVYKGLCKGKIVAVKTTKPHTTKEYLQSLLGEIKILSHIGRHDFIVNLEGAYTRNLQKGTVYLFMEYCGLGSLESYLRSNRKNYVPVEDLENPNGLQKGNSDQLADSNVNCITSKHLLQYAHQIAKGMDFLASKEVIHGDLAARNVLLVDQNTAKISDFGLSRKLYGYINYIKKKEEPLPWRYMSLESLKEMTFSTSSDVWMYGVLLFEVFSLGDVPYPGMSWSLEFVEKLEKGLRMLRPKYAPVNVYKDVMLRCWDINPADRPSFFELSNYFHQALHEITSQDYTEMVLGVESGEARYTNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE33</accession>
    <name>A0A1D2NE33_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Origin recognition complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03174</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the origin recognition complex (ORC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ORC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE33"/>
    <dbReference type="STRING" id="48709.A0A1D2NE33"/>
    <dbReference type="OMA" id="EFYKTQP"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="8">
        <location>
            <begin position="342"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="9">
        <location>
            <begin position="568"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="638" mass="72423" checksum="767E318B126E3612" modified="2016-11-30" version="1">MSERRSMVLRNHSTPTKDRSYEDVIQTPIGRHKPVLEQETPKSLRSVGRRAASGRYQRKDNSPSSKSNEENEGIQKLNESTPNSKLSRNRQRSIIYTPTINEDEKSIKAVFRLGPDSGNDTPTPRRSSRPLRQSVLKSNALSKYKNDLPSSDEDSNVEGPTPKSTRHLRRSYFTKEDSDEYSAEEDELSESDDDKIEDDLSTASSNDEDETTPKGRQMNAPDLSQLPLTPDVLHQVKGRAVKRRLAVDSPVATSSQTMSPNPEVYFLAENRIKFRKKAKVQEAMNDAMKGKRRRRKVIQSADSRLPEHIPSDFSVTSEATKATVNPENFIAGKSHDEEAHNLLKNVIENEFPHWLGLFRDSFNVLIYGYGSKLCVLKHFEKFLNEKYLVVNLNGLFPKLNPRKFVYGLCEAVNPDLRVPHGSSLEAVAKEASSLLAAESHPDVFILLNNFDSMVLRSPQMLTALCWMAQVPYIHILASCDTVNAFLGVTQSQALQLRFCWSHCPTYIQYREELKWTPDIYGDESKAATQKSSLKYVLQSLTGNARKAFALLAQLQLKQMKSRAVQKSKEAYAGVRFQELAKECREKFIAHSDENLRTLLVEFFDHKLIRQTGKGRHLENMLLIELDVDTMEEIISDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEI8</accession>
    <name>A0A1D2NEI8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEI8"/>
    <dbReference type="OMA" id="GHEITMS"/>
    <dbReference type="OrthoDB" id="8250911at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23992">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006170">
        <property type="entry name" value="PBP/GOBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01395">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00708">
        <property type="entry name" value="PhBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905456" evidence="1">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="16737" checksum="47188778C99C77BB" modified="2016-11-30" version="1">MNTFGKVTVLAALAIFVILQASLVRSEDKKFQCDGHEITMSEKQVEGMKACAEVIGIKSMEEMTPDKIPCFAKCIMEKGGLLDAEGKPHKENILMNIDAAVPEEMKSTYKAAMEKCIDEHGHHLSPKDETCMSYGPMAMCGMQAFKNICKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEU4</accession>
    <name>A0A1D2NEU4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000064">
        <property type="protein sequence ID" value="ODN03752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEU4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="7553" checksum="5CF4FFE0C4720679" modified="2016-11-30" version="1">MLTLGTRGAGIFIGGTERNATNNATATFECHPLGERHGSLLLGLASAGVIANVSLAGLILARKSLRRLEKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG12</accession>
    <name>A0A1D2NG12_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">Ocin01_02665</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG12"/>
    <dbReference type="STRING" id="48709.A0A1D2NG12"/>
    <dbReference type="OMA" id="FCYAPRI"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF41">
        <property type="entry name" value="INNEXIN INX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="654"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN04035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="747" mass="86627" checksum="9185EDF0CB6CE9F7" modified="2016-11-30" version="1">MFNVFSSLKSLVALNKVIIENGVFILHCKVTVSILLVFTILITTKQHFGEPIDCLTGSEDVKFGRAVDEYCWIHSTFTVNELLHPKKVGKSVVQPGVGNYHPSRKTKTDHKYYQWVGFYLLFQAGLFYFPRFIWKLWEGGRLKVLTVSLDSILNCSESEVEQRKGKIVEYFLRNYHRHNAYAYRFITCEIVNCANVFGQIFLTNVFLGYHFATYGQEVIQMLIYSNSDDSMGHPMDKIFPKVSKCIFNHFGASGNIINQDVLCVLPLNILNEKIFIFLWFWFVFLAMVSMIGLLYRLLTIALPSVRAQRLQLIAALCDERVVQRVSQQCGYGDWFLLCLLGKNMDPVFYADIISELAFCFGSGYRMYGRRRTRNGCESTTVQKTYDRTSIIDPVYDTVDVSFRIFVVSSLLLTTKDLTGDAITCFGDKQEKDEILNAYCWIQSTYSVSGYFHDCNAKKDCIYPGVGPVSRDFEEIYHRYYQWTSVTLFFQGLLCYAPRFLWKIMENGLQNTLAYDRKLQYYPITTTDDDQGPVQHLKRLAIYFKTHRGQHQFYFLKYCCCEVLGLLSVVANILITDVLLGYKFLHYGRNVLSYWWGSYNCDDCDGDNKNPISPMTQVFPLLAKCSPLRSYGPSGNIFTPDPVCVLPLNTLNEKIYLFLWFYLIFELSVSTLALLHRLLMTFVTKARVILLKFKCLGVKSKVVEDVCHRTNIGDWFVIYMMSKNVSRQFFQEFLEMLWEEIHERKLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG67</accession>
    <name>A0A1D2NG67_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02445</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000050">
        <property type="protein sequence ID" value="ODN04244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG67"/>
    <dbReference type="STRING" id="48709.A0A1D2NG67"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000013">
        <property type="entry name" value="Carboxy-terminal domain RNA polymerase II polypeptide A small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040078">
        <property type="entry name" value="RNA_Pol_CTD_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01124">
        <property type="entry name" value="C0.1:_RNA_Pol_CTD_Phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="7">
        <location>
            <begin position="206"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="4">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR640078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR640078-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="467" mass="50459" checksum="8075A41B4C4171E3" modified="2016-11-30" version="1">MCSSKMDSIITQVTKESCYPELSVSSNSLSGEEVVNQKAVNLESSTNSNSSSSKGTNSLLRQRRVTDKCVKNESTNNDRSSATPPTSSSASNFLRKLLNSCCCCVRKQSSSSSSSSKNGNSCSEQKTNQPGAWGDGTEPHVLSRGGEGVCVGGGPNTALASSSTSSSLGEDASVNGITAGLCSVVVNGEQRAGSTGAYLLPPCLPQDRNRACMVIDLDETLVHSSFKVAIIHFHLPVVNYHPISNADFIVPVEIDGVVHQVYVAKRPYVDEFLQKMGELYECVLFTASLAKYADPVADLLDKWGVFRTRLFRDACVFHRGNYVKDLNKLGRSLHRVVIVDNSPASYIFHPDNAVPVASWFDDSTDTELLYLIPFFERLSSVENVYTVLRNSNHPYNSINKESSIASQGGSPVTLPQYSLVHGASPSASSATSPITQLPNNNIQHSPPIHDEIISVVTHFDEHNNTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGD2</accession>
    <name>A0A1D2NGD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein zer-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGD2"/>
    <dbReference type="STRING" id="48709.A0A1D2NGD2"/>
    <dbReference type="OMA" id="EEAGQTX"/>
    <dbReference type="OrthoDB" id="5783533at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031462">
        <property type="term" value="C:Cul2-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056845">
        <property type="entry name" value="LRR_Zer-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055142">
        <property type="entry name" value="ZER1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051341">
        <property type="entry name" value="Zyg-11_UBL_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12904">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12904:SF23">
        <property type="entry name" value="PROTEIN ZER-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25013">
        <property type="entry name" value="LRR_Zer-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22964">
        <property type="entry name" value="ZER1-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Zer-1-like leucine-rich repeats region" evidence="3">
        <location>
            <begin position="258"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Protein zer-1 homolog-like C-terminal" evidence="2">
        <location>
            <begin position="455"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="854" mass="97321" checksum="C84755C61AA00DA0" modified="2016-11-30" version="1">MSSIISIQSSEESFSPPTLQEICRFYCTSNAKTLLFASQKRNQNDADVENSKLRKSIQLPVPIWEGLLEDYHGAPEDYLPLILAVIKCRKNFHIKSIHLPNTPTLTDERLRLVMACFPASLDIHNCPSLTKKAVAVINEYGQHLEFLQIGSSTQILTIDVEAWILKLKETPQGIRKVVRSIADFFNGRSVTHEDDGETHGLLRTPKLKKLVVWGLHVNQLQHLHLKNVTSSHENAGGGDAETNVVKVDYWEYLTRDFIHELQHLDLSSCQELNDLSFLLEAKDNLKALHLHDVLFDYDEKTWGILKQLTELRFLDVSQYNELASIFPNPDEILDKIVTALPHLVGLDISGTNLPGFEPEGFMPCGIMGLESRKETPLKFLGLLTSHYNASCRSNIPATKIAGGKDMEQLLIALQFYTQRENSIKKVIRMLYEKMQEMGADDFLPSHTILRLLVQAMKNHVYDKHTQIVALAAMFIVIRRIYKGPTKCLHNVDINQVLYWISKAMNVHSRDVSLLKNGMLNLLFLVPYIDMAPYTEDIAPILLEVATVATAGQDVFMTKAVAFTLHNMTRYLRKSEKEKLGESDIIEKLCLIVDNLIVHVAMDQMTVFWTLLWNITDDVPSNCKQFVKAKGIDVCFRFVGACLNFLNCGVNLANLQDAQIPMFALLSNLLQHPSFEAQIITLEQIANVFDLLMKVDSAGNEKLCFHICGFLCKVASKKISYSLESPTRQKILHKVFRIMSKLDFKKQFDYDFRHLTPLSTLLEVKDAPEIHAWVLWTLVNLTETNPKRYCNLIATDKLIKIKSLSERFQLPEDHRCSTVINRLCRTLTNNVESIMNPEQLSGYQKLAQIVREKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGX3</accession>
    <name>A0A1D2NGX3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pseudouridylate synthase 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a uridine in tRNA = a pseudouridine in tRNA</text>
            <dbReference type="Rhea" id="RHEA:54572"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13934"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGX3"/>
    <dbReference type="STRING" id="48709.A0A1D2NGX3"/>
    <dbReference type="OMA" id="WINYFGH"/>
    <dbReference type="OrthoDB" id="447290at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF31">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="6">
        <location>
            <begin position="279"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="618"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="625"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="644" mass="73798" checksum="E12777B594BBD747" modified="2016-11-30" version="1">MSKYTAIRSEEEVGILLRVGNQQRFNGLFKERYSDFHVNEIDLNGKIVQLGSLEPPQERKSEISVDDPAICSWIPEDIRVNINGFQERLENAGSVPKSDKLWTERIEVKVTTLDKEERTRIHKWLTNFDKLSSETIDKDGEKYIVALYETKNNRNKRRPATRAKYTHCTLYKEGVDTFEAIGLLSKKLRIKPSLITFCGTKDKHGKTTQRISISNIDASRLAQISNESRNVKLGSYEYLPHHLRLGDLKGNHFKILLRNVLVDSDQVINAAVESLKSQGFINYFGLQRFGSYEVSTHAVGKCILQMQWMEAFDLILKPKSNDQDFVKKAKTEWFTNRDPVAAIKKLPPWYRSIESNLLHGLAKYYSKNDLMGAFLRIPRNSRHLYIHSFQSFLWNQVATYRIKEMGLQPVVGDLVYVDKEHDDFYVEDIDDEDYEEESGNGQPSDRLLSRPTVKTLTPEDLENYSIYDVLIPIQGSQIRIPENGTKDYYDKLLKEEGLDSDCFLKFKPVADQPKGAYRKLLIRPHNVSHKIIQYGDADPVDTFIPSELDKAQHENKMNNEAAECASNDTEVGTKDKKCVIVEFSLPSSAYATMALREIMLSSSEIVATQTYQVIKIEPETTDPAAKNDNDEPKAKRIRTDLTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHC1</accession>
    <name>A0A1D2NHC1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRAL-TRIO domain-containing protein T23G5.2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000038">
        <property type="protein sequence ID" value="ODN04647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHC1"/>
    <dbReference type="STRING" id="48709.A0A1D2NHC1"/>
    <dbReference type="OMA" id="RCFFIDA"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="67"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="226" mass="26632" checksum="724DDA0F7C4A66F5" modified="2016-11-30" version="1">MIIDEVQENKCLDELRKLVKDLEQSDAALKRCLRARNYDVNKAEDMVRKTVEWRKTNKVDEALTWKIDDFIIQQFPIEYTGVDFNNRAVAFVPVGSWPVREMLENGHREQMLMYIYVCLEKLIEQIEKTGDQFTLIIDLEGMTYWKVAHYETIQMTLKVFRDFEANYPERLGEALVINAPLVLNYVWPTYQATIDRLDVEKGSVFGIQLCQVYSSDPDSHEYRIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHV0</accession>
    <name>A0A1D2NHV0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Interferon-related developmental regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IFRD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHV0"/>
    <dbReference type="STRING" id="48709.A0A1D2NHV0"/>
    <dbReference type="OMA" id="QCFEAIF"/>
    <dbReference type="OrthoDB" id="18978at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039777">
        <property type="entry name" value="IFRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006921">
        <property type="entry name" value="Interferon-rel_develop_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007701">
        <property type="entry name" value="Interferon-rel_develop_reg_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354:SF1">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05004">
        <property type="entry name" value="IFRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04836">
        <property type="entry name" value="IFRD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Interferon-related developmental regulator N-terminal" evidence="4">
        <location>
            <begin position="57"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Interferon-related developmental regulator C-terminal" evidence="3">
        <location>
            <begin position="432"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="491" mass="53394" checksum="A1D77A60D2F87BB6" modified="2016-11-30" version="1">MPKPRSGDKKGKAGTPKKGKSRRGAYGMSDDDSVNGDSASVVSMNSERGSYEDYDNGNGEEHDEGVTIFGVGSREAMEEKVAEAIDGIIEKSASIRTSSLSTLVSLLSQNFNPDLILGRRETLRDHLEKIFKRGQGSDQAVAANVHCLALLQIGALDSDMATEDFNALKPFLQSLVLDHTASVAARVKCCEALCFGAFISEGCSTDVMKIITVLEPLFGCGTKSKRTLSEDENSAHSDGAKSVKIPKNSSTALAAAAMSGWSLLITLMSDEYLNSRAYRWIAELQSLLDQPDLEVRLGAGEALAIVVDLCGLTVDDSEVDTDYSSAEESDVDSSLNGHQNGHRKKTSISELIAKLRQLSVESHKYRAKKDRRQQRHSFRDFLHAVEEGSGPGQVMKFGVGEVLEVDTWGKKKQYDAICQVVGAGINRHLIENTLVRSILELGTPKPVVSDGGIGAKQAKSERQYMNAVNFKARCVSRGKAREYRMATLEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI86</accession>
    <name>A0A1D2NI86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tudor domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI86"/>
    <dbReference type="STRING" id="48709.A0A1D2NI86"/>
    <dbReference type="OMA" id="ANECIIT"/>
    <dbReference type="OrthoDB" id="10023235at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20379">
        <property type="entry name" value="Tudor_dTUD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050621">
        <property type="entry name" value="Tudor_domain_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948:SF29">
        <property type="entry name" value="FI02030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948">
        <property type="entry name" value="TUDOR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="1">
        <location>
            <begin position="319"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="1">
        <location>
            <begin position="534"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="605" mass="68664" checksum="04E4982B726E2D2D" modified="2016-11-30" version="1" fragment="single">FFNRPRYLSGEESKMINDISDTEKVYKGKLEYFRRPIFSNTPYKYELVSVVNPYDFSVRIKDDYTAEHATRLKSLMENYSDTLRQDKVGDISRYMSSHGIREMYEGMPVIAKTEPGEGVSSITRGEVLAFDDNKVDVMLVDEGGVVSTVHQKIFPMTVDILRVPVLAVPCRMAYIVPDEPTWPVSVNYKDKFSGGVQIIYFQDLIQSTRSYEAVLEVDGVNVGIQFFHTGVASPVKLPSAPIYELESSGQPQYPLFDYAPWVGLKNMAFGVRTFVTDDKPSLRTRCILQLQPELVNTIQDDISKYVDETPEDIQKTGLKVAPGVCCLARYGGGDYYRAKILKTDCNEAVVDYVDYKEVATIPVNDLIKLPESLLNIPEAANECIITDFVMEACTDLQKLSDNINDKDLYAVIDSTDSNILGNALLVSLFRPIDFSGPDESFCEVFGVSEKPTVNREILQEFQPVSQALVNVFLKSRLPDPNKIYPGAMISVINGWDSMWIQLEEEQVVADRISAELTMFYQNLGSSEEWEFENSLTVGKYVAAQQTDEEGLVWYRAKIVKEDKDQCLLHYIDHGNSEWVKKVEVFPLHTYFIKDHLMTFEVMLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIQ0</accession>
    <name>A0A1D2NIQ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chromobox protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIQ0"/>
    <dbReference type="STRING" id="48709.A0A1D2NIQ0"/>
    <dbReference type="OMA" id="NEANAKC"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00034">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="39"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10093" checksum="E582E57A9710E2A8" modified="2016-11-30" version="1">MVKVNKKPSRSSETKKDGGPPPEKDSPGQVPAAGFGKGLQAEKIVGATEGDDGKLLFMVKWKDSDATELVTASEAKVKCPQVVISFYEGIIKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIU4</accession>
    <name>A0A1D2NIU4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000028">
        <property type="protein sequence ID" value="ODN05184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIU4"/>
    <dbReference type="STRING" id="48709.A0A1D2NIU4"/>
    <dbReference type="OMA" id="ITICYAS"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905619" evidence="2">
        <location>
            <begin position="25"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="134"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="349" mass="38874" checksum="35DFE0FF6F4C8D3F" modified="2016-11-30" version="1">MSLLTYCRHIGIVGALTVITICYASKPCPPLSVLPGTEVHCEFPVDNRAFNCLDANSSVPKGTIARYKCERDANFSENYIKCKCRGRWGGLRRFNDFMSSCNISDYSIDGPAELNLTDTQIYELAPGDPRQVKDYQEDGAAYHNFYRQIHHSPSLKLNKTLSDAAQKWADQEVDKPTLRTQDWSDRWYSQNIYRIQSYTVDAREAVRLAVAAWYQGAYRYDWENPSGQSAFTQVVWKSTSDLGIGVARKGNLTMVVADYWPPGNVVVENGDVSARWAWFRENVFPPNPINETLMTTTTTTTTMSSIPSSSSSPSNLPSSSNSSIPSNSSSSLSEVDHSTGVVDYPTTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL22</accession>
    <name>A0A1D2NL22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hermansky-Pudlak syndrome 3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL22"/>
    <dbReference type="STRING" id="48709.A0A1D2NL22"/>
    <dbReference type="OMA" id="WIRESCN"/>
    <dbReference type="OrthoDB" id="10255480at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017216">
        <property type="entry name" value="HPS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029437">
        <property type="entry name" value="HPS3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28633:SF1">
        <property type="entry name" value="BLOC-2 COMPLEX MEMBER HPS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28633">
        <property type="entry name" value="HERMANSKY-PUDLAK SYNDROME 3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14761">
        <property type="entry name" value="HPS3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BLOC-2 complex member HPS3 N-terminal" evidence="2">
        <location>
            <begin position="89"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="955"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1210" mass="132716" checksum="74335423E290180D" modified="2016-11-30" version="1" fragment="single">RIGRCDEASAVAVAGQSVVVAIEDSINVYVAGHSFQTPESDLTTCDTGFGGQFYHSIPEIGVPISFAQLEKSLSDERRVDSSTSEQPQSGSCSSSVSSIESDTEIKLSHSFSTVDLVQSLSYNKKGNYLLCLECRDAENGESKSSSIRVYFHWNKKYDAMPMRTRIAGVSPSANDLEKLVLTMVELPLTSPATAVASCNISGHLASLSAESVINIFSFRIKEVSGRGKMQYPDFDRLCTVEVPGCSLESLSFMANFISCSGGGKVHVLKVYKSEKAWSPSMVTADKYDLANLKNTARNKARIDSPRLARVNKAKQNFDYSNKVTYDPNDESVTVHLPSITRANRKRAGNTVIAEEYTGEISSNKSKIIYMSSASGVTVEDVLRLSLPQTTSGSSLSHDRFTDTKLYPVRIGDCLGGVTLIVGLTKEAMMYHLPTKDGCHPIRIANYAFTAPLVTFTFDSLFFHALTESGLETYTGRSLYYSLQDYEGFERYKNACPLKNERPCLVGIRPFVKVRFMAANESLICLLACPTPMGTTVSSQPTFSPPLSPSAVLSQDERSWTIYSLELPDIDLLHEDTMRVAKSQENQSDTYVTLLCELHLMLRAHINSTPDESLYYMPRYRNLCKSIGLEHLKVFSTLTAESTEGNKLGTAPQIAANQSCFGLSTSDELLELGVTYLCMAGLDIQQIFALENSTLIQDPQYIAGTVRLIDVLLSSYCAKNDDKHNFSPALSSSIVDFLSRNSTETLVDLVIKVPFLRENNSTRLVEILQDVAATRGCSGKETIALVLTLIAAGGIESNIRSQIRDLLDKVNSEDLSTFLQLQLILDRGAKHVALTDVTICLTAVNSDLPTVILSEAIRNQEVTVSEVMLAFAKAVNLNSESQVQRSLAKALRVILESYFADKISSRSDSSRKLGATELPTNVAFSEDERHAALALVRSYLSDISLSPTNTLMKSSAGDSNFTAEASSDGSHENSNVENMKASQENEAAIPENIIDKADIIARNQIFGKIPSFVNFLLSVETPGGSMTPVSTSFSPSLFSNLENMDSYIRLLSLLSSPCGKIDGVKDSVLNFVYNSSSSVKSTPLQLVLQMFCEPVETAVSILISRQPTTVLLYAKEMFGKSTLKWKTLVTQLKKRINLNPTTPDADMFSTIIESVYLHLANTLSLTELEEVLEKGSDDVAKFRSTCKRVELANSYASMVIQISTDYLQNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL60</accession>
    <name>A0A1D2NL60_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BolA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL60"/>
    <dbReference type="STRING" id="48709.A0A1D2NL60"/>
    <dbReference type="OMA" id="QTHFKAV"/>
    <dbReference type="OrthoDB" id="521617at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050961">
        <property type="entry name" value="BolA/IbaG_stress_morph_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46229">
        <property type="entry name" value="BOLA TRANSCRIPTION REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46229:SF2">
        <property type="entry name" value="BOLA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="104" mass="11623" checksum="EA098DFD763FCBFC" modified="2016-11-30" version="1">MATRVERINNVLQAELTPIHLDIINESHMHNVPKESETHLKVVVVSSKFNGVPLVRRHQKVQELLKPELDTGLHALSIVARTEAEWEKTKTVPASPNCQGGFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM34</accession>
    <name>A0A1D2NM34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protocadherin Fat 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00355</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NM34"/>
    <dbReference type="OMA" id="YNRQDPS"/>
    <dbReference type="OrthoDB" id="6491773at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034332">
        <property type="term" value="P:adherens junction organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016339">
        <property type="term" value="P:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044331">
        <property type="term" value="P:cell-cell adhesion mediated by cadherin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007043">
        <property type="term" value="P:cell-cell junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000094">
        <property type="entry name" value="protocadherin gamma-C4 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF422">
        <property type="entry name" value="CADHERIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1739"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="61"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="155"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="268"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="520"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="655"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="736"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="841"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="975"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="1071"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="1187"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="1283"/>
            <end position="1405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1769" mass="196918" checksum="B87950FC92FC4F6A" modified="2016-11-30" version="1">MRRTFSFRWDHFHGAIYLLLISGFSEFLHNYGIAVTLAQSSNTFRPNQPPVFLPGGDLSKFSIPEDTPVGSVVYRLKGSDPENGELQYSISGEYFRVNKKSGDLTLIKALDREVEPKLDAIISLTDDGNGLEPTTVSLRREIYIQDRNDNPPIFLRRPYSFKVSERTRVGATVFSEIPITDADFGPNAQVSLICDKEETPEACKTFKVEVQKVGDGKFVGILSLEIPLDYETHNSYPMTLIASDGVNTAKAFVAISVLDIQDQSPKFYGGPYVFKVKENSTPGTKVGEISVQDGDVGNPRNLQLRLIDEAENKYFRLTNVERDMFTGTYTALVETTNYTLDAEDEFIRENLGVYELILEAREIPLHAEDTEPTLITRTGVAVIIEDVDDHLPTFIPPQFTRILRIPYNPEESWMFPDFRVEVEDSDVDHHNSKFSLKLDWNIEDSPYEIDDVFAFVTPSNEDPTIQSKGIITLEVLNISKLEPGQMIDLQIGAVQNGHIVSNLNVPIEVAPGPKIIPIFSQNVYRVALPEDIAEGELVAKITAKNHNEIPGIKYSLIGIGAEKFDVNEDTGEIRCKAKCLDYERNQHNFFLIKAKSGEKVDDEVPVLFYLDTIERNDNYPEFEKVPGLGTHTANGYLVRRAVPDGTAKFDPAFYVKASDPDVNDTITYSLQDHSVKESGIFINEQTGELELEKTLKWSEAGEHRLTVTATDSTGKATHQSVLIVVQAIPNIPPSFPYKVQHVEVPETLEKGSQIFTVKAHDPDGQDSAIRYSIESQTTQDLFAVEETTGTLRLNGQLDYEEKQRIYPIKIRAQDEGKPPETAQVYVEVHVTDENDELPKFSEKRYTVEMSESSKPDLVVMTLKAGDKDDNAFLEYSISCPCQVWDASGSMGSSADAESYFKNLRIDPESGEIVLVDTFEHKKTAVLEFQAHVQDNNGIKLQSDTAAVTLYVTAAERTKPIFGHPWTTGNPWINLTIPEDLDNGTVVVTLNAWDYIENLPITDFRIIESDSDIFKLNGSQLIVKYDGDSQLDYETQDSYILAVKAIAPHGAESIANVGIQISDVNDNAPTFTKPEYKGKVLENSGYPTPIVTVEAVDLDGSPGYGSVRYALTGPQSHLFTIDELAGVVQVAPGAEIDREKDESHLITVVAMDTPSGGPFQLTATAQLHILVQDENDNDPVCKVLEFLVAENAPVGTAVGNISCVDPDENPKLSFQMRDETHLSLFNVDKDTGKISVARVLRGRGRSAPYIMTVIVEDGKERTVNLAVPIKIANVIPNDGKPKFVNENFTVTISEASMRGTPVLYVKGEDTDSFDNGEGRLHYHLMKQFSPCQSLINAGNVSRVDDVDLFRLDEITGVLTLKDSVDREKNPCFSVLVSVEDSGIPPQSETQFFEIHLSDVDDSLPYLPKEVRNLQLTLNESTKVGSIVYNFTGEDRDIHPNNMITFEISGGGKDLFKVIPTGDQSAKLILNADLRGMEHEALTVVIKCHPKHKKLSVPECSSKVNIKLNRDLKGAVNYLGKTKYYEMILGVASGTTVGNLIGNVGMPKKFKSSVQMFHPMGGLSSSPYNVTDMIRIDDETGDIFVWDNLEKFSNGHLRVQMIDDSGTMKKNLKVFIEPNEQLLSADMVEFPKLQKWMDEVDGFLNSPEEKTGIKRGHFHILTFDQTNSYDGRTKVCFQLLENENMVSQEKALQILDNGDLQDIFLKYSFEDIQKGCPTRPRLPARLALTAGTSRFWIERSLIGIASVVAIATISAILILCLISRKRVKDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMS7</accession>
    <name>A0A1D2NMS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rho guanine nucleotide exchange factor 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMS7"/>
    <dbReference type="STRING" id="48709.A0A1D2NMS7"/>
    <dbReference type="OMA" id="METDNSM"/>
    <dbReference type="OrthoDB" id="4066896at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039919">
        <property type="entry name" value="ARHGEF10/ARHGEF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12877">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12877:SF15">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19056">
        <property type="entry name" value="WD40_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="453" mass="49349" checksum="4704C4442BC1A979" modified="2016-11-30" version="1">MVRYGFGKLPQVQFVQALPIRKTRAGLQLSCAAPVTLYNKASKALEMTDLWVANSDGYVGQICILTLHPEPAITSCNGVCNSRITCIVSVPPPCYTHLAGTAYHSDSFPASHDPSHHPHPHLHSLGYESEDDFHRPKLGHKASGEHWSVWLGTEDGSLHVYDCNDSVRVKKNRHKVQHKAPLNCMVYFERRVFVALGNGDVAVYVRNPNGKGWLVNEATWVTIGSAMNPVTKMICVHAYIWCACGSQIKVYGENGGMLELLQTIQVVIDGNQMPRGISAMVAADQQVWIAVQGSSIIKCYSTVTYECLSETNVAPEVAKILAGCDDIIRQHKSACLRVTALLVAPDKSLWIGTSAGVLLTINSSGQNPKIAPLCHGHTGQVRFLTCCVTRDSWTVISGGDGYEEFRAVPSFLSNSGASFSSMVTGFISDSSGDLSGREDSTNHLLIWKIPKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0M4</accession>
    <name>A0A1D2M0M4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Titin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008532">
        <property type="protein sequence ID" value="ODM86516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0M4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="38702" checksum="408AC0DC34A36B9D" modified="2016-11-30" version="1" fragment="single">TSNALLYSSKGTVNQKYSNWSNCPFHLSLKVEGGHVILYKWDKINESQEIETRAILTNESTHFENVFRLHSITKEANCVRLLNETDSCPNCFLAEENNYTVNAIVFYAKYRTEVLVFKECSVCRKKRCIERRFYWYWKLSPSVLAEEMVQFEVPPVIYTNLKFDVICRVSVFLFAYGTIITHHLSADKEEAMPTEYLTPFGYRQVERSMAFNATGDKNISCFSPLKKSKDWITKTQMVQVEDAFPPSIDNFTENKTELVTILPNQVSQSLHADCNFSGNPLPSLKWIFPMKNLTGKVNVIHGTNFSRIVFPKWDHDLAGTYVVKLETLLDSHLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0X8</accession>
    <name>A0A1D2M0X8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymethylenebutenolidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007978">
        <property type="protein sequence ID" value="ODM86620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0X8"/>
    <dbReference type="STRING" id="48709.A0A1D2M0X8"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="146"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="28869" checksum="8ACE8386E6A928ED" modified="2016-11-30" version="1">MSSKGSAAFEVAALATLSSSCPSAWKLGLLWGWSLFGRISKVSALIIELSDDPVAGLLVLVSVMCIVHSTKINYDGSNIPKHGKIIEANYTPRGEEYQIGNLTIYENPNGSGKRVLIHIYDILGMSTNIRQVEEYWNSENFPIADQEEVDAWVEQYASWNGVAKPDVQNIINHFRTTENITEFGIFGMCYGGLMSTIAAQEIPEVKAAGWVHPTYITTEMANDVKFQCVFATSNDPDYIPFYEILKSKFGTLFITDAFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1K5</accession>
    <name>A0A1D2M1K5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypermethylated in cancer 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007003">
        <property type="protein sequence ID" value="ODM86844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1K5"/>
    <dbReference type="STRING" id="48709.A0A1D2M1K5"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="12905" checksum="FF1AA23D030A5BE1" modified="2016-11-30" version="1">MSPVMSVKFTRNERRFSCSECNVVYKSKQQLNHHMKAVHNPETHICHICDNIFTTAKYLNQHVTRTHSTPGAEESWNKCPKCGMRFCQKYLLKNHLLHSSCRLGKRKETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1M1</accession>
    <name>A0A1D2M1M1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone H3.3 type b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_19861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007104">
        <property type="protein sequence ID" value="ODM86821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1M1"/>
    <dbReference type="STRING" id="48709.A0A1D2M1M1"/>
    <dbReference type="OrthoDB" id="4025405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810:SF1">
        <property type="entry name" value="HISTONE H3-LIKE CENTROMERIC PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="3">
        <location>
            <begin position="88"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM86821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="20799" checksum="537D5D3EA8CED112" modified="2016-11-30" version="1" fragment="single">NSVIVEYHSPGFWNKSHVHLNVNSSSAGAAEPEPEANREKEYGRKEEGDPHCHAGNPAEEPANWGLGFHSQRKRGEATAVTRFRRGPGFLAMRQIRRYQRSTEMLIPRLPFQRLVRQVTQKSLKLKVKPKFQAAALEALQEAAEYYIVGLLKTPTSSPSTPSESPLCQGHPTCPSHSWRDIVLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M271</accession>
    <name>A0A1D2M271_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006272">
        <property type="protein sequence ID" value="ODM87056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M271"/>
    <dbReference type="OrthoDB" id="3621146at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903392" evidence="1">
        <location>
            <begin position="29"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="71" mass="7908" checksum="3E5E73FCB4282B37" modified="2016-11-30" version="1">MKPSKVTVLLIATFCALWLGMMVEETSSAPQIDWGCTISCTYWNACYIKNGFNKDQCPPYPSNCDCSRFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3G4</accession>
    <name>A0A1D2M3G4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium-and chloride-dependent neutral and basic amino acid transporter B(0+)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_19171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005138">
        <property type="protein sequence ID" value="ODM87510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3G4"/>
    <dbReference type="STRING" id="48709.A0A1D2M3G4"/>
    <dbReference type="OrthoDB" id="6366319at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF323">
        <property type="entry name" value="SODIUM-DEPENDENT TRANSPORTER BEDRAGGLED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="427"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="486"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="618"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="789"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="489"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="627"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="792"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM87510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="831" mass="90119" checksum="2DC75234E21ABE3C" modified="2016-11-30" version="1">MARLKSYGKVVHGFVLAPVAALFVLAFKMVGLVQTGSSLFGQTKWSSFFFASQTWVAAAREAFFTWGLLGACVMQITAHNRHSHSLKADSVIVITVTMIVLMLSAFIGNACFSILTAQNSILDQTRFSYVPSSFESNSTYRFLDLANPDEAVTDMYDHHHISFLMGVRVIKQGSDFHQRSGYQVLRLATELFPATMAVLAQTGISSFWTVLFYFAFVLFGIAQQIAIWHCVIKGIIAVKGKVLRSWETTITFFVCGLGFVLGLPLCTETGIFIEYFMDYAIGSGWWIMVLYLLELIAVFIVRGAPYCGENIVTVLITGRNRISAILAPLISFIWNVIMPVAILVLSIASFKNGNIRELYDWNPKHGYRFWHIWTREVGSLIQLVPILAVPFVAILQSCRYLSTGPPDLFDRMQQLYRPNSQGLFGNPLSGSFNDNGSTGTSSSRNGSSSRGPEDPPPKYTPPPSYSTATGAKIAKFLRNSFRRSIRRLSSPSGPSTSSASPDNLPPPPNYASVILEINSQRSHQSSSCAQQSTSGASSLMNPIMVPPPSYDESTMSGPSGLPTKKGGEPSSANKLYQIQLSHTLGRSLAEGSKERASLRRIASDITSRDIARMLRASLRRTTRDSPEASTSAGISQPSASAYSTNSSPAARGGVIVTIPASAESGGTPCEYTFGPSSIEKVEYDLEMLNDLSLSDRQLPSSSGIDSNRQNNTASAFGFNFGFNRARNRNSNDSQLALITSGVYEDLTVTSGGLMGALVDGAIEIDQFTQLNLPRRDSLSQLNVLDLGGAGSGNSNTNPTFQIHNASATNSPHHQHLAQSERGAASAADSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3T6</accession>
    <name>A0A1D2M3T6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ISXO2-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005037">
        <property type="protein sequence ID" value="ODM87571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3T6"/>
    <dbReference type="OrthoDB" id="424490at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053164">
        <property type="entry name" value="IS1016-like_transposase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47163">
        <property type="entry name" value="DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47163:SF3">
        <property type="entry name" value="PROTEIN CBG18017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="18530" checksum="34901A05F22DCDDB" modified="2016-11-30" version="1">MVDRGVSEHTCIKWRDTFREVCHTSIKKNSTKIGGLGKFVEVDEAHLFRRKYNRGHRVQGESIWILGDKALEFLAHETVVHRTDFVNPIFREIFTNTIECVWGKLKRTVRRGGKLARVDQFISEYLYRTMLGVKYGPHNYSSQLVHFIKDIKSSQKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3U5</accession>
    <name>A0A1D2M3U5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004902">
        <property type="protein sequence ID" value="ODM87653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3U5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="38294" checksum="05AA28E10AF15915" modified="2016-11-30" version="1">MQPNSPASTHQLNGTHTINETENQRRKSARVSLVVGRRSPAGSKRHANRGAWRKLLYKSSQASTIPSHPYEQNGHQFSRLLEIINNPRSRECLKNKMNKCNNKFPSFNSSMNGTHTTNKQTENQRKKPARVSLVVGRKRPAGSKRNANRGDVEKVAIQSSQASTSSQSSIRTKRPSIFQTARNNQQAKKPRVSQKQNVARYVGDDVFGNYHMIKSLDQFKTILQKAQPKHNLSTELVKKLHLRVNHWLEDVFVDLCENTNQPYGFVTFQNLKECMMDQALVPDGISDDDLLMTMKQKMSKEDFKRSEGILYPSRHSKRNDTDDYFSGIKKEPLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3Y0</accession>
    <name>A0A1D2M3Y0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEAT repeat-containing protein 5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004845">
        <property type="protein sequence ID" value="ODM87685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3Y0"/>
    <dbReference type="STRING" id="48709.A0A1D2M3Y0"/>
    <dbReference type="OrthoDB" id="192608at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040108">
        <property type="entry name" value="Laa1/Sip1/HEATR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663">
        <property type="entry name" value="HYPOTHETICAL HEAT DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="482" mass="52976" checksum="A89E5AC61FF76939" modified="2016-11-30" version="1">MLSPASGACTPASGRMMGLSDEETVQVCSKTFRNMESQSRIETLITFEKICGGKNTACSSSHKEMYNIAKGHGGENLFSVLIHPCQSTRLSAAWALRCLCVAIRRETHKSIEWCLQAFYTLKPSPEAVSRYSAALSSGSLNTPCNSHAIGKIVFNCGGTPQNWKPESKGVPRVANDWSNNDDRELRSESAPPQCFSSGGMLSPRAQKSWKARGDASIHRCLLHCPQLLTDEIVQRLMVPIESTLAMMTNITNTLMTYGPQLKAAADNLRFRLYQTLTLIKPNYFESETLHAHALLRDLELTLNDNVANTTSSLFTRICQSNTMFNSFVSDPVSLPFPPRVPPSPLPPHSRSPATPASPQKPPRSDPTSSRYPETFATALALPDFRLFPQITRWIGLLSPSTRLSLNPSQRRARRFLPRNPSLGAAFPPLLQPRVNPFSARIPQARHELVSTALLSSTDLPPSRGKMLSAIITGVGPARKLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5J4</accession>
    <name>A0A1D2M5J4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Villin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003904">
        <property type="protein sequence ID" value="ODM88245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5J4"/>
    <dbReference type="OMA" id="YEDINFG"/>
    <dbReference type="OrthoDB" id="9973045at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="11639" checksum="99A0FAC1B0F541F0" modified="2016-11-30" version="1" fragment="single">SSNPHLLSVFAKQIILYEDSVFQGATYNVTRFYKLGMFVRCFDLPSNWHDRVSSINTNGNCVYAWTLPGCSGKHLHVAPGTPSHYSLSELRFDNQIQSVEQCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M657</accession>
    <name>A0A1D2M657_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003560">
        <property type="protein sequence ID" value="ODM88467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M657"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="15532" checksum="7EED6E40B472B523" modified="2016-11-30" version="1">MGRLYINLCQQNVLVGAFGATLVGIATSHFAVPPGRIHSLLAQRLLLGQPVKALTKIVLTTSVMASSLSFKLAVRAISGGVIYDLIKRSRDEGKNTLALSNDHWINAGCLPQAWAAAGICSVGAVMSEFIPPQELTTKNWFGRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M668</accession>
    <name>A0A1D2M668_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_18272</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003628">
        <property type="protein sequence ID" value="ODM88412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M668"/>
    <dbReference type="STRING" id="48709.A0A1D2M668"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000012">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0488">Methylation</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM88412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="16434" checksum="60AE54BDEBEF8C4A" modified="2016-11-30" version="1">MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTSTPRGRPSLPWTLSMLSSDKAELSTDSEVLCLLWSLGLDWSLLSSYCFGAGAAGAGLGASAGLAFGAAGFLAAAFLGLLVALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7N5</accession>
    <name>A0A1D2M7N5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_17742</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003048">
        <property type="protein sequence ID" value="ODM88941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7N5"/>
    <dbReference type="STRING" id="48709.A0A1D2M7N5"/>
    <dbReference type="OMA" id="RMEQYEW"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="62" mass="7003" checksum="93B85E4281A97F4D" modified="2016-11-30" version="1" fragment="single">TGQAKPDEIDMLVEISKQIEGHTICALGDGAAWPVQGLIRHFRPVILERMEQYEWKAAAKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7X1</accession>
    <name>A0A1D2M7X1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isopentenyl-diphosphate Delta-isomerase I, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002971">
        <property type="protein sequence ID" value="ODM89022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7X1"/>
    <dbReference type="STRING" id="48709.A0A1D2M7X1"/>
    <dbReference type="OMA" id="AEWGEHE"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF0">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="98" mass="11093" checksum="58EEC17127998E3A" modified="2016-11-30" version="1">MAMTIPKMSYSTAVSKLQPDTDALDESVDPIQRQLLAEQCIVLNDHDKVIGHDTKRNCHRIVNGDVLLHRAFSVFLFNGKGELLLQQRSKTKITFPLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8U7</accession>
    <name>A0A1D2M8U7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Host cell factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002671">
        <property type="protein sequence ID" value="ODM89403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8U7"/>
    <dbReference type="STRING" id="48709.A0A1D2M8U7"/>
    <dbReference type="OrthoDB" id="10001928at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043536">
        <property type="entry name" value="HCF1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059124">
        <property type="entry name" value="Kelch_HCF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46003">
        <property type="entry name" value="HOST CELL FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46003:SF1">
        <property type="entry name" value="HOST CELL FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13854">
        <property type="entry name" value="Kelch_HCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Host cell factor Kelch-repeats" evidence="3">
        <location>
            <begin position="58"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="462"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="626"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="629"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM89403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="654" mass="71749" checksum="3210F2A25C8763F0" modified="2016-11-30" version="1">MKTENEKGIVGSVNMEEAGGNVGGSISEDSECKAPPSSSSTVGSGPPGSSSENKLVSWYRINSDWAPPPRQGHSALIIHDRFMITFSGGDGTMFDDLHTFNLITKEWSRKSATGRIPEGMLDYGMDIYGDQIFIFGGIKDNCILSSDLYELDTVSWEWSKLELTPPQNYSPPCARACHTFTVVDGRFYLFGGLTDKTYSEELNEPVLLGDLFVLQLRDKEWCWDVPTTEGYLPYPRISHSAVAYKDTSSKLIIYGGSMGTERLGDVHIFEVDSGTWIQPDLSGRFPKPRSCHSATLIGTRMYVFGGYTHKPLDRIVDPETETCVKAKPECSSALFCLNLETQTWERAKGDDGKFWPQPRAMHSAAGTQSKIYFWGGTTGGKYVDYRSICHDELVVLEVEQPSEAPGKVMYLHQLDENGFVVEWKAVEGADSYILQVCPFPENKTVKKPAVYGPARVEYSTLPATPAPHPQARFRNPTTAPPPSRMPPRLPIVQPKQPRVGTRMPPPTYFQRGTGGPIIQVGTRPLFPQGVATPGSTLPQMLPSRHPMSTWPGGSHEYLVVRNRLRRCYTYYEPDGEGGQAAGRTSTPPPQGLFLPGEAQPRRDRVIINGLAGLADVASGLTPVATTSLSPQQASPAPPVTTTATVDATPHSVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9P9</accession>
    <name>A0A1D2M9P9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein LSM14 B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002431">
        <property type="protein sequence ID" value="ODM89707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9P9"/>
    <dbReference type="STRING" id="48709.A0A1D2M9P9"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lsm14-like N-terminal" evidence="2">
        <location>
            <begin position="95"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="436" mass="48169" checksum="D10E67E54E25FD72" modified="2016-11-30" version="1">MAQNEGNNLASAEGQRARLIAIVKPMPRTTECDDESWLMDFPTTSTPLNSQVETDNPELNPEEDTETGFNPPCLSECVELRELILGQIWTYARLSIDATRFIGCKISLTSRSNLRYEGPCKIQLDAVSISIAEVRAFGTEDRVTSRPVLPSYRIRKVLTFCFTRVQDVHVLELPETQNVPHRVQTTQRMIFIGAKFGSQAVKIYTVSVCPRTLESGKSNFLLSPSEQSDAFDYDQLDDKLRIKRATAGSSNIELGSSIALLISVSTTTSRTSNSPLLLKSQLDQLSNPFLFAALAATTLAGAFGSTSIQNSEASKVNDVLSATQHKFRSSHSSSPFDPNFQSGEIVDSSSVKRELHDKFPAVTSKKLTNDHTTSKPDDTGYYLNYLPVSGTVVAAKSWRRSDVVASTKKMLPLDQSLQLNPNSLVVDRPQPVYVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9S3</accession>
    <name>A0A1D2M9S3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002415">
        <property type="protein sequence ID" value="ODM89728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9S3"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="14695" checksum="5BEB06531C13BDA4" modified="2016-11-30" version="1">MLNWLKETNGKLFEGFEHIVADWTSYEEKVDGENKFTKLMQESGLKVKTLQILNRNFFYEDIEVVLDLWLSANIFLHRLTEPMKMELREENRKIMTEFAGVPLNSKSLMKEYEIVYGVVDKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAA0</accession>
    <name>A0A1D2MAA0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002303">
        <property type="protein sequence ID" value="ODM89900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAA0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903710" evidence="2">
        <location>
            <begin position="27"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="86" mass="9064" checksum="73FC21AFA9027B5C" modified="2016-11-30" version="1">MASTKTISVGLCLLILVASTFLVAESQVWEACEVLCGDILDNMPMIRGRASSRGGRRPPPPPRPIYHGGSGGSGRPEIPPYLGMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAC4</accession>
    <name>A0A1D2MAC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002282">
        <property type="protein sequence ID" value="ODM89937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAC4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="252" mass="27816" checksum="C615949B79B7E33C" modified="2016-11-30" version="1">MNQINSTSVASIDKLLLPQVRCLALSAIFSTKMDPSPDSFKPLQNGVKFFAIFDAVISALNAVLVVSILLVALFYNGEENPLNENKETVAVFSGIVIFIASHQLWMAVRLYNGAKLKESGKCMSWVGFTLVTIAIYIIGLLFSRSSVNFKDAILAAILMLIVYKVFGIAVVARFAARLRLSEQETTAFRFPFVVARRQQTCPTVRVSVIDLPPTYFDAQNPDTLQVDPPPYCEILVAKSRSDYTNSVGFVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB23</accession>
    <name>A0A1D2MB23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002160">
        <property type="protein sequence ID" value="ODM90112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB23"/>
    <dbReference type="OrthoDB" id="8057533at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="132" mass="14902" checksum="A767D79DB7F9AB1F" modified="2016-11-30" version="1">MKQVFSNQASVIIPHITAWVEQFSTLRKLISTTAIILMFIKSRAKKIEASYPVTPLERIQTRNHLISRVQAICFPDEMRRLKEGKEIQSSSPLIKLIPYIDGAGVLRVTGESTTLQSHQILSTPLCSQNVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBB0</accession>
    <name>A0A1D2MBB0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Extracellular exo-alpha-(1-&gt;5)-L-arabinofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16394</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002054">
        <property type="protein sequence ID" value="ODM90287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBB0"/>
    <dbReference type="STRING" id="48709.A0A1D2MBB0"/>
    <dbReference type="OMA" id="WMAYHAN"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903747" evidence="8">
        <location>
            <begin position="18"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="6">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM90287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="37696" checksum="02AFDDBBAA55272F" modified="2016-11-30" version="1">MFQKLFFMAMLFCMANSQEFTNPILDRNSADPFVLKMGSYYYLTLSENREMEIVMYKSPVLTNFRDAESKVIMRAPPGYLDLWASEIHNVDGELWMYFTMRTENREHRMYAVKAENPNDPMGNWGNPIRMLPDWDNVAIDGTILKMDNNRNYFVWSSGVTGHGSIYISPMENPFTTSPHVVMIREPTQDWECQDICTSEGPFFIYNERKAFMIFSASMTWNPNYCLTQSSIELSRDPMDPSAWEHAPGPVFQRNDAESVYTTGHASFTVSPDERETWMVYHATESQTDINGFRTARLEKIDWNQDGPIFPQAHGYSHPQPVPSGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBE5</accession>
    <name>A0A1D2MBE5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002094">
        <property type="protein sequence ID" value="ODM90232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBE5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="79" mass="8647" checksum="4CBF01C0BB320E97" modified="2016-11-30" version="1">MKGLSATTVFIFPTSFLPILVPPSNRIQAAKLGESLTKNLSSTAAILIIIVVSKLVLKPQSFNIRSWRHSSFVSYTEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBL3</accession>
    <name>A0A1D2MBL3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">Ocin01_16322</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002012">
        <property type="protein sequence ID" value="ODM90360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBL3"/>
    <dbReference type="STRING" id="48709.A0A1D2MBL3"/>
    <dbReference type="OMA" id="LLCFPKW"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF39">
        <property type="entry name" value="INNEXIN INX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM90360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="186" mass="22573" checksum="6594CA38656BFA0B" modified="2016-11-30" version="1">MTTFLMPDAFSRPSSFAHPGLYNDYEQETGKKHYNYYQWVCFVLFFQALLCFPKWLWKTWENGLMTHIVCELNTGLRTEAEKNKKKEILIKYFLKHWNQHHWYTFQYWFCELLCLLNIILQMVFMNRFFKGDFLLYGLKVLTLDDEDQEDRVDHMIYVFPRVTKCIFRKFGPSGSLEKLDAILSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDL4</accession>
    <name>A0A1D2MDL4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fanconi anemia group A protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001669">
        <property type="protein sequence ID" value="ODM91106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDL4"/>
    <dbReference type="STRING" id="48709.A0A1D2MDL4"/>
    <dbReference type="OMA" id="CRNEEST"/>
    <dbReference type="OrthoDB" id="2287188at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043240">
        <property type="term" value="C:Fanconi anaemia nuclear complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003516">
        <property type="entry name" value="FANCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055386">
        <property type="entry name" value="FANCA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031729">
        <property type="entry name" value="Fanconi_A_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12047">
        <property type="entry name" value="FANCONI ANEMIA GROUP A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12047:SF2">
        <property type="entry name" value="FANCONI ANEMIA GROUP A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24781">
        <property type="entry name" value="FANCA_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15865">
        <property type="entry name" value="Fanconi_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fanconi anaemia group A protein N-terminal" evidence="1">
        <location>
            <begin position="139"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Fanconi anaemia group A protein helical" evidence="2">
        <location>
            <begin position="463"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="544" mass="63621" checksum="5F447CCBD96C55A0" modified="2016-11-30" version="1">MEGNCNLWCRMESERAKIPNIVRDEYIPIFIVKCLHEKLEPGDAGGVVLKKFGAFNHTTEESMWTDDTFLEDNVDFEGMFLLSKENLNYVGRVLRFAKEAYECFHLDKKHFGRYFTDEYEHPCLELLYLMDALYNLLPVTGYLMWMKQLSQKKYFKEQFLSFVFSPTAFRFEDRQRSTRILEHFLECIILNHYCNPDNKPELKSSKLLCGDILKEMAVKLSQEESYQANPTNYSIVLAIFKDVDIPNSVRTRYFSDNLTIILNMGEKTISARKRSLTISRKMIRSTLSSVNVMEIVSTILQTADFNWEILLFLITVWIKEKEKNATTLLKDAIKSLIRDGLLKRNENDVTTGFILARHCSLVASTFFSRYEKWFTNMFESGMYSPANDAETFTFLTEMLTSWLPNEPSCFLHVHATFWPFVPKGCRETWNDYISLAKVRISEYKEVEEAMQFEPNLNDPIQYEVEMAIKAFEKNGKIPQSILKLWIVRKKYYLESLLPVLLRKPSGHSGVPLSDSKRRFIELLRREGKIPDAMYTEYKAAIRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDZ1</accession>
    <name>A0A1D2MDZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Icarapin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001648">
        <property type="protein sequence ID" value="ODM91163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDZ1"/>
    <dbReference type="OrthoDB" id="6346805at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="251" mass="28201" checksum="897DDC23D3A9A7D9" modified="2016-11-30" version="1">MHNMRQQMDSLFSSLFAPNPGFFNPNRQFFPRPFFPSVPADSSGEDTKEFLDFGKLPPNYKNSTSETKVVDGKVIEVNKTVHKISGDNSNGFFQFSVIKIRPSEDTPAAEEDKQQPEATVIEEKKPDEAPEAEVTTIKAQQESEMNNPSLNEVDQDEKMSNTKYETDPGLLEEEPSKDAPVSLPLTQEVIYDFVPLQLQSMPLIQASKGDDGKNKPHDLSTDLRINNLMANNENGRLRTLVDPDEIEIIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEP2</accession>
    <name>A0A1D2MEP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001532">
        <property type="protein sequence ID" value="ODM91487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEP2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="20486" checksum="D43E279500CB0B89" modified="2016-11-30" version="1">MQKQKETLPQPQVRQVQRDVKVEVDAETNSRISMDLYDDDDDSVPFEDYDNFESLSTEPEEERKKDDTTTTGGRIGGADEGGEDEIFIKEEPLDEDEQETDVHLKYQPDEDEEGNNDEEGSYYEPSSCSELESDCDSYSKLEEDTSPVQKKWCKILSLTEKFLTQGLPLLDMFQVIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MES2</accession>
    <name>A0A1D2MES2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC transporter E family member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001531">
        <property type="protein sequence ID" value="ODM91498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MES2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="29" mass="3295" checksum="61C78613BE833025" modified="2016-11-30" version="1">MARYEYPTMTKTMGSFRLDVTVGPVQPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF53</accession>
    <name>A0A1D2MF53_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sidoreflexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_15173</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001527">
        <property type="protein sequence ID" value="ODM91511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF53"/>
    <dbReference type="STRING" id="48709.A0A1D2MF53"/>
    <dbReference type="OrthoDB" id="6608471at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140300">
        <property type="term" value="P:serine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00798">
        <property type="entry name" value="mtc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF8">
        <property type="entry name" value="SIDEROFLEXIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="325" mass="36115" checksum="233FEC98A3BE2084" modified="2016-11-30" version="1">MSFSKGRVNLYEPRWDQSTYWGRLRHFINVTNPLNLLHTREDLEWAKNVVLKYRSGETMSHLSEEELWYAKQMYDSAFHPETQKLIHPLGRMSAQVPVNILIVGGMLSFYKSHHAIMFWQWVNQTSNCFLNYSNRSSGEYISGLQLGISYVLGCGGAMAVSSTLKQTLTQTGKSFPLLSRFIPFAGLAAASCVNVSLMRIQELVQGVAVTDSKGNRIGLSATAGSLAVGQVIVTRVVNSAPALLITPVIMHRLETILPSLLRYPILRFPKQLVVIGVILGISTPMTCAIFPRKEAIPVTSLEKEIQEKAKKAPGSPTVLYYNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFR4</accession>
    <name>A0A1D2MFR4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short-chain dehydrogenase TIC 32, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001407">
        <property type="protein sequence ID" value="ODM91828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFR4"/>
    <dbReference type="STRING" id="48709.A0A1D2MFR4"/>
    <dbReference type="OMA" id="DHFRTEK"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF264">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER ON CHROMOSOME X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18857" checksum="ABD1468646682B97" modified="2016-11-30" version="1">MEIDHFRTEKRSNQVVVMTGGPRGIGFDIVKNCFRVRNIAASENGILEIRHLGISSGRVKFLNLDLKSLRSVRKFANEVLASTEGSRIDLLLNNAGIVSPSYEVTQDGYESIFQVNYLSHFLLTNLLLPRMRDTAVKKNESCHILNTSSDTNRGGRIDFTELETGQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFT7</accession>
    <name>A0A1D2MFT7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_14817</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFB7 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001393">
        <property type="protein sequence ID" value="ODM91867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFT7"/>
    <dbReference type="STRING" id="48709.A0A1D2MFT7"/>
    <dbReference type="OMA" id="RIACKES"/>
    <dbReference type="OrthoDB" id="268414at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008698">
        <property type="entry name" value="NDUB7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05676">
        <property type="entry name" value="NDUF_B7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="14" id="KW-0830">Ubiquinone</keyword>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="16665" checksum="8DF1B5EAF85007DD" modified="2016-11-30" version="1">MGGTVSSRPPASPVIILEKPLSKTTPDWKTGELCADPNYGFEEQGKRRKERVMVATEAEMISAKVPPKLRDFCAHHYINFEKCKKDKFPFVYRCHPEKHNYEHCQYEDYLIRMKDYERERRLLHRKLRKEKKNGGRNHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHT5</accession>
    <name>A0A1D2MHT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Laminin subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001222">
        <property type="protein sequence ID" value="ODM92462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHT5"/>
    <dbReference type="STRING" id="48709.A0A1D2MHT5"/>
    <dbReference type="OrthoDB" id="10011303at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Laminin G" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="53" mass="5906" checksum="1BB94AF4B7E83602" modified="2016-11-30" version="1">MSVHFKTNEPNGLLLYLGNEPGRKEDDFMAVEIEKGYPVLTVDLGSGPQRITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHV9</accession>
    <name>A0A1D2MHV9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-phase kinase-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14103</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001196">
        <property type="protein sequence ID" value="ODM92579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHV9"/>
    <dbReference type="STRING" id="48709.A0A1D2MHV9"/>
    <dbReference type="OMA" id="EPTERIN"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000124">
        <property type="entry name" value="Protein CBG09126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="5">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="4">
        <location>
            <begin position="116"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component POZ" evidence="5">
        <location>
            <begin position="161"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="4">
        <location>
            <begin position="275"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="325" mass="36850" checksum="9D34215BBAD06A2E" modified="2016-11-30" version="1">MKVPKIKLQSKDGQEFVMDVDVAYSSKIITTILEDLGLEHHEDGEPDDVGRIEVKGEIFELVLSWMEHHKNDPRVDGVTSSNGPVVISEWDADFMAKMDQETFFDVVLAANFLDIKPLFDVCCQKIANSCKGKTSEEIRNLYITTRGEPELIKLSEGDAPQVKLKSSDGALYSVDKDIAMLIPTLKVMLENKGEEVIALPMAYSSTLEKIIKWVQHHKNDDAPAPPPEPTERINRNTSGSLDDVEQWDLDFLNEDLNNPGDLFEVAVLARKLTIKGLEDLIAKKFRNIFMGRTTDEIRAILRLPDDLTEEQKHFIPLENKWVEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI61</accession>
    <name>A0A1D2MI61_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein GDAP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001192">
        <property type="protein sequence ID" value="ODM92602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI61"/>
    <dbReference type="STRING" id="48709.A0A1D2MI61"/>
    <dbReference type="OMA" id="IHPTFWT"/>
    <dbReference type="OrthoDB" id="365077at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106">
        <property type="entry name" value="GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106:SF72">
        <property type="entry name" value="GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="2">
        <location>
            <begin position="52"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="553" mass="62515" checksum="AECFDB5AC7616B69" modified="2016-11-30" version="1">MRMMEHMNIDGSSDPEDSSGAMKWSEMDLSHVNLNQNLSSWPHHLSTRNFESSPFPVDPVLNSRVSLWFGDILALSVDGLTQTTNETVDTLPDHILTRSGPAYLSEIRHQLRSIRTGEARTVASHPNLPCRDLVLTVTPKYSEKHKTAAETALFSCYRSVLERACEKNMDCVAIPTLHKGGGPSPFPDELAAHVAIRTVRRWLEQGHSSPRLVILAVSDHNLFQLYTSLMVSYFPRDSLHENYACSRLSIPDIGDEEGAPWLPDRKIRIFSNPAGGGAHSKKGEESGANPSFAHHPKNLNLNLNGGSGSDDYAEEGEGIMEQLNKDFLQMKEDVDKERLIFNGRKRRSLASLNETERHIAIEIETKERQERILRRARTEDLSSIERTGCIFRNGIDRWGRHLVIVVGKWFRPEAVDLDKAFLYLVRILDEINGPYSVVYFHTSTGGENRPSLRWMRAVYDNMEYRFKKNLKSLLIVHPTMWTKVLCWWFTTFMAPAIKLKLHNIAGLEELYNTVEPSQIQVPAFISEHDITINGYAGVAYSHTHSAASTPVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI75</accession>
    <name>A0A1D2MI75_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucan endo-1,3-beta-glucosidase A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001177">
        <property type="protein sequence ID" value="ODM92673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI75"/>
    <dbReference type="STRING" id="48709.A0A1D2MI75"/>
    <dbReference type="OMA" id="TASTHFY"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08023">
        <property type="entry name" value="GH16_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904077" evidence="1">
        <location>
            <begin position="30"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="33"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="300" mass="34984" checksum="70CC422128ED5299" modified="2016-11-30" version="1">MDIMQAIGKKFGYILCAVLLIHLLEFGDGAKRKDWTGKLIFEEHFNGEKLGRNWEIVGNCEGKGHKDTNLECFTTREDNVRLRDGLLIIEAWPEEWHPKELWAKSKNFTSGKVKMINELGYQYGTFVVRARLSKGNHLLPSIFLLPAYQDHDNCKYEEVDIAQGRGQRTSTVIVGAYFGRQWNHASSRKTEKAIRNTDFSAEFHEFTLVWKQYRLEWFVDGRLIYTIPMYYYSDWLLQDESNLPCNMNKKLFQQELQLNFALSVGGSMFPQAGYGDLTLDDAKNWTKPTLEIDWVKIYDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJW2</accession>
    <name>A0A1D2MJW2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Gonadotropin-releasing hormone II receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13422</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001035">
        <property type="protein sequence ID" value="ODM93260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJW2"/>
    <dbReference type="STRING" id="48709.A0A1D2MJW2"/>
    <dbReference type="OMA" id="LHQDPHE"/>
    <dbReference type="OrthoDB" id="6435638at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24230:SF163">
        <property type="entry name" value="CORAZONIN RECEPTOR, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24230">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="79"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM93260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="324" mass="37489" checksum="05C244CBC2C1B99E" modified="2016-11-30" version="1">MTSQPSVFLHVNSSPEIIESEGTMTKYIPEISPIYEADNFSLLENTTTNGTLPIDMIFNNGHLPAVILYPLLMTLSAIGNIAVFTVIVRLRFKGELSRIHLLILHLTIADFIVTFVMMPLEIGWNYTVSWDAGDGLCRIMSFLRIFGLYLSSFLLMCISIDCYYAVINPLAIYEANRRAKWMLAFAWIGSIIFSLPQALIFHVEVHPEFRWYQQCITFNSFPSQNAELAYNLISFFFLYVLPMLTIIYCYAHIMAEMYRVNSQKQSDVMFRRSNIGVLSCAKIRMLKMTVIIVATFFFCWTPYNVMSLWYWFDRKSAQEVDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKS6</accession>
    <name>A0A1D2MKS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000937">
        <property type="protein sequence ID" value="ODM93656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKS6"/>
    <dbReference type="STRING" id="48709.A0A1D2MKS6"/>
    <dbReference type="OMA" id="LMEKWIA"/>
    <dbReference type="OrthoDB" id="20727at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="2"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="143"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="176" mass="19275" checksum="251E8D51A6AB906C" modified="2016-11-30" version="1" fragment="single">ATGWTPFMYAIKDNKTAIGDRMIELGCDVNTKTKDGIYPLHIAALHGRDDTVRFLIFKKADVEVLTEKKKQNALHIACTRSSGNSASILRALLAVLPKDARLQKDGDGNIPLFVALKTGLRGACQELLTNQAHEQLRVQAGPMKDTALHTAVRKRDLEVARIFVDSGANVDATNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML38</accession>
    <name>A0A1D2ML38_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13076</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000946">
        <property type="protein sequence ID" value="ODM93601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML38"/>
    <dbReference type="STRING" id="48709.A0A1D2ML38"/>
    <dbReference type="OrthoDB" id="7770689at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF127">
        <property type="entry name" value="BLOODY FINGERS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="294"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="522"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="580"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="803" mass="89481" checksum="4B309437C3EA3EC6" modified="2016-11-30" version="1">MGGHGKPSCFVCLKSISQNHNDRVNDSELFRKFAGVLSGYLQLSSLSSHGGSTGDSENVSIFCVQCISMISNACDVYKEFRAIEVHLSKQLGELGELMMGEKKMSEGLSNSFKETLTRLEIRVSGRIPGYVEKVRNVVALKCALKGREIELEHDHRPLENKKTVNVEEGYHAEKEIHYIKVELESDADDSPMEGGFDDDRSEQSFPNDSDTVQVKQMGGDKNVENSELSSVSSSSHSSDSEFVEHSSSTRKPRKKKLHKKAIHPSQESAIGGIRKKLEGVKAKSKAGQGVDNDVECNCNLCGMPFENMVLFGRHLLIHEDREPLKNIACHYCWMSFALPQSYDNHLKTRHSDKAELKFCCDNEQCEELSFGSTEELNEHLKTHSEEVHICIKCNWGFLDFGMLELHRLIHLKSVRGNFPCPKCTCILHGFPKLRDHYNIRHGANMALYKCPKCSVSCVTTSNLKTHLKSHLKTHENGNQSKPPHSMYPTLSCGKCDVTFPGSVKGKERLRVHMKTMHSEVKHPCPVCQEIFISERAMERHMKQTHQTTRMSCKFCNKECASRVSLKKHIATIHPSNPEEHLCQYCGNVFSNRQYVLQHIRVVHKELFEGQGKNVCLNCGEKFHILGLLKKHSKTCQSKPAAGGVEDNIGVNELAPVHEQKLVKCFSLAELILTRRESSYLHHPTNIHQDFCVINSKHAMGDSREAGEPVTGQPERGPLMNKVKDVQSSDVQLDPTINLQGEKCGGVMNGSGRPPLSSDPCCASCVYSWWYCGGMSDGRLCCGDCAGCDLSGCDCSGCDCAGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLV2</accession>
    <name>A0A1D2MLV2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Signal recognition particle subunit SRP68</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Signal recognition particle 68 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12801</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SEC6 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SRP68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000898">
        <property type="protein sequence ID" value="ODM93882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MLV2"/>
    <dbReference type="OrthoDB" id="10047020at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15481">
        <property type="entry name" value="SRP68-RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3450.40:FF:000001">
        <property type="entry name" value="Signal recognition particle subunit SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.70">
        <property type="entry name" value="Exocyst complex component Sec6, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.40">
        <property type="entry name" value="Signal recognition particle, SRP68 subunit, RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042532">
        <property type="entry name" value="EXOC3/Sec6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026258">
        <property type="entry name" value="SRP68"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034652">
        <property type="entry name" value="SRP68-RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038253">
        <property type="entry name" value="SRP68_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16969">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0733">Signal recognition particle</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM93882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1310" mass="150422" checksum="3DADC3EAE3430923" modified="2016-11-30" version="1">MHWKRVKSLLVVKAEPGNSTWYLPFDNMSRISNAEAASRAKAVERIAGLIQRPDQLERVEEFRKREARKKASKEAMLKTALQSQLEGVQRGMELLKQARVDLEKVGKHTAEIQKGLKDVPTLAKELQEIREESFLHSQLVMATDNMNNIFNINKNLDKAHSLINEGNLLHAHIMLSELETSRDELLFELFRMGNRTEQTMLLDYFSDVEKLSDSLKRQLTLNLKRTINVARKQPSVLVTTLRIIEREEKADSVAMQRTDISGFKPPGRPKKWKNHAFEILESSVTERLEACQLESRDENKMWLVRYLEVMRQLILEDLLVVKSLCVPCFPPAYDILQRYVNMYHDCLSKLLEECISGLEGYEFISLLAWVLNTYLGPDLLKNLDLDLQPEQIPTNLLPDPVVQDLKKKYLAVQNFTQFIIAVVNNCLNFMELAHQTKDKYWKSAVGDSEAAHRFENVLKTFENLREKAAEFLLEEAFLDLEPHFQELITRNWLKSRTAVDTICVTLEDYFQDYVHLKQKNFELVMAYGKNLVAKKYLLSVMSRKVSFKNQDERREASDKIVHEVAQIRRLFERVGATPQGKQSACPFNAIDAVSELIKVEDLDILSLELHSFIKHYPDLTKEQLMAILSLRGDIGRFDLKQKASEIIPGTTSGHRGPIPLSIFSQVQIPPFFMHKLAWIYSKGTNTTHEAMDLNSTHLTISCSIMVAPEVGAAVGNSDLKGDDGDSSALPLISLKGLLEFRKCWMLCLISVLDAPSFVVLFMERQQQHGLRHSDFQRYHGYCSRRLRRLRETLHLPQGDRRHFKRKDISVAEIDAEKADSRFLEIPLTVVERAWACAMELKQEANTEPRKRFHMISRLRKALKYSEDLMKIAQESTRVDARTKLEIEAYVSFINASFHFEMEQWEEAMSAYKKTQTTKLVTNLMLIPFRFRSIYTQIAQALGEHPESALYTEKTSEILPAMRFCAYKTGAELKISELSSEFQSAAIQDMIAQRPKMSEITFRKNKITVPTEKIAGLLVRIDEFEKKQDKKVEMYEEILVDLRDGIQSIRDTVKIEQQQTGKSKPSWLLSYLLYLRLKLTISRTELMMQEKNQAKDCTRLVEIILHNLAEMKTIQLLDADEDFQLEVDDQISVFKGVRCRYLADALKTGKRWGESLALYEKTNEHFRRAQKGLPADSPCHDIIKRTLAYTESAVLESHAQAILARLNPDERDKQDAALKLTRREEPLIDRLEDFVLDESLVSGEPNVAPFPPEYKPVPCKPLFFDLALNHIQYPKDEIQEQAGVSSKKSPAAGGASGLTGFVKGLWGWGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMJ4</accession>
    <name>A0A1D2MMJ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000868">
        <property type="protein sequence ID" value="ODM94044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMJ4"/>
    <dbReference type="OrthoDB" id="8284057at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904273" evidence="1">
        <location>
            <begin position="25"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="18604" checksum="339AED4F5C5F86EC" modified="2016-11-30" version="1">MGLWKISMINFIIFVEFALKNVQCEELDSNSYSYSDEDYYQLAAEYQQYQDDLPMPAVHKAAEANKLDESASAEYLQPAGITQEHLFRKELMNGLPYCYYWYKMRNRKNLDKLREKYSPGRIELANGKIGSYQPTAEEYEAYEELIKAIIVQEMYDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMN5</accession>
    <name>A0A1D2MMN5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_12577</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000859">
        <property type="protein sequence ID" value="ODM94105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMN5"/>
    <dbReference type="STRING" id="48709.A0A1D2MMN5"/>
    <dbReference type="OMA" id="ERHENAN"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="20334" checksum="800D5F166D66AAC2" modified="2016-11-30" version="1">MGETQRKAQSELDRVVGPSRQVALSDKALYGLPYTEAIILETLRLSSIAPLGVPHRMIADTIFHGYFLPKDVTVIAGLYTIHHDSKIWGKDVNEFRPERFLNEDKTRVIQHEALMPFCVGRRACLGEGLARDTLFQFIASILQTFNIEPDPDCPVRSVETVKGFNVEPKPFTFVLSFRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMT8</accession>
    <name>A0A1D2MMT8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha-mannosidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000814">
        <property type="protein sequence ID" value="ODM94380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMT8"/>
    <dbReference type="STRING" id="48709.A0A1D2MMT8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050843">
        <property type="entry name" value="Glycosyl_Hydrlase_38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607:SF3">
        <property type="entry name" value="LYSOSOMAL ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="15708" checksum="AD923F80E7994545" modified="2016-11-30" version="1" fragment="single">LDWTKSHLVRILVETPFVSVYGTSGEPVSSQINPKLGTTENGDSGIFDGYYELVFVAYLQPLALTTYEIQREEDRKRASHPVPNHNVAVSASVQCRNCGYNINSLDQQSYITLENDEIAAYFDGKEGLLKGIHKKGRAIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN66</accession>
    <name>A0A1D2MN66_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000800">
        <property type="protein sequence ID" value="ODM94499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN66"/>
    <dbReference type="STRING" id="48709.A0A1D2MN66"/>
    <dbReference type="OMA" id="ANIVFIR"/>
    <dbReference type="OrthoDB" id="10608496at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF4">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="324" mass="36128" checksum="2312D050F3CCD413" modified="2016-11-30" version="1">MSFPSGILKNNSVSPISPHHYPISANPYDGTGGRNSTVSFIASSMSMLPAGLDSPSRIKLSEYDLDEDLEPLAEKNMVFIRQLPQDIERLELVRLCTFSGYINVPNKYQVVSSSGDRLYDVIETTDGVTRRLFRRDQPFTMRVINNYGEYICELIGDPGVGGLGAFVKLKRESSILGKVVQVNPLFACCNFSPRYNVQNEKGKTVQKILWQRGRFKSCMFTEDFQVYSAAKSGGLTGSISRQTKAICLEDYSQADTYALSFQDIQMDRIQKTLLVAAVIMLDFQFFEGREGSDLWKVAVCCVLVILVILLVAGIIIYLVAESAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNL3</accession>
    <name>A0A1D2MNL3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bystin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000783">
        <property type="protein sequence ID" value="ODM94593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNL3"/>
    <dbReference type="STRING" id="48709.A0A1D2MNL3"/>
    <dbReference type="OMA" id="RRMPVLW"/>
    <dbReference type="OrthoDB" id="2192561at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007955">
        <property type="entry name" value="Bystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821:SF0">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05291">
        <property type="entry name" value="Bystin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="461" mass="53157" checksum="D4FD0F2665EDE3A2" modified="2016-11-30" version="1">MGKHKKDKLSKAIRDSPINRPGGGLGEQLHNDQVVNPADQKQRSKDKNRMEEDPEFVDKKTTKRILKQARLQQQQLEDEFAEEEETAGGMGSQRRSGKSSVRKSVRLEETTTGQDSESEDDDEFKLVSGDEADEVEQERFSKEISIDPDDEQALEMFMNKNPEPTKKLGEILMEKLTEKQTEIESQFSEAGVVVHKVDPRVEEMYEGVRDVLKRYRSGKLPKAFKLIPRLANWEQILYITDPNGWSAAAMYQATRIFASNLKEKMAQRFFNLVLLPRVRDDIDEYKKLNFHLYQALRKALFKPAAFMKGFLIPLCESGTCTLREAIIIGSVLAKNSIPLLHSSAAMLKIAEMDYSGSNSIFLRVFVDKKYALPYRVIDAMVYHFLKFEKDKRLLPVLWHQCLLAFVQRYKEYLSSEQKEALQGILRVHLHQQITPEIRRELMNSKCRDEVIQENAAMMVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNX5</accession>
    <name>A0A1D2MNX5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Solute carrier family 41 member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_12128</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000788">
        <property type="protein sequence ID" value="ODM94555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNX5"/>
    <dbReference type="OMA" id="QQWYMIV"/>
    <dbReference type="OrthoDB" id="5791097at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.20:FF:000001">
        <property type="entry name" value="Solute carrier family 41 member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228:SF7">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="11">
        <location>
            <begin position="148"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="11">
        <location>
            <begin position="360"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM94555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="529" mass="57360" checksum="C21E36DE807D0696" modified="2016-11-30" version="1">MILRTIKAEIIMECDTRRNSQPGGNRLQIPSLGGDGSERRGSDSVIVVNSRSPKYFELKVLNGGEKSTLLDNSVKIPIPQISKSIADPKTASEKKRKIPKEETFCSIALEVLFPFLIAGAGLVGAGLVLNKVQFWPVFTELPETLILVPALLGLKGNLEMTLASRLSTQANLGNLDSRHAVWHMTKANLSLVQCQAIVVGFLASIGAFVLGWIQDGRFELNHALILCTSSIITASIASFTLGVVMVAVVLISRRFRINPDNVATPIACSLGDITTLSLLACISDFFYCVVESHQWLCPAIIFGYFISMPIWITIAKRYDLTRSVLYNGWTPVLSAMVISSCGGLILDLAVRKFDGIAVFQPVINGVGGNLVAVQASRISTSLHIDHQLGSLPEGAENVCSNPFRVFFARGGHARTARALLTVLIPGQLIFVYTILSIKADQTAVPSIFVLFYLLAAVIQVMILLYIAEVLVKSLWLHGIDPDNSAIPYLTAIGDLIGTGLLAKCFIFMFLLGYPVDSDTVESLHSLEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP24</accession>
    <name>A0A1D2MP24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase-like protein 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the methyltransferase superfamily. METTL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000767">
        <property type="protein sequence ID" value="ODM94688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP24"/>
    <dbReference type="STRING" id="48709.A0A1D2MP24"/>
    <dbReference type="OMA" id="VIGITWG"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF164">
        <property type="entry name" value="HISTONE-ARGININE METHYLTRANSFERASE METTL23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="23288" checksum="7410B2551152B12D" modified="2016-11-30" version="1">MQASYGLYVWPSAPILAWYLYEHRQYLPGKRVLELGAGTALPGVVAALLGAQVTLSDSAKLPHCLDQCERTARVNGVGDKVKVIGLTWGLFLNTLTQLKGQVDLLLGSDCFYDPSVFEDLISTVAYILEHNPQAKFLTTYQERSADWSIEHLLKKWGLNCKHVPLNDLSNSGSVDLLGLMQDHTIHLLEITHSASPATERSHDIEDIEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPD0</accession>
    <name>A0A1D2MPD0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde dehydrogenase 5, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000773">
        <property type="protein sequence ID" value="ODM94665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPD0"/>
    <dbReference type="STRING" id="48709.A0A1D2MPD0"/>
    <dbReference type="OrthoDB" id="10671838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904346" evidence="1">
        <location>
            <begin position="18"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="2">
        <location>
            <begin position="321"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="720" mass="78574" checksum="738FD45C2D3F4E27" modified="2016-11-30" version="1">MLWEGLLGIWILNPTMSNVSQNVTSVKKQSSSGIQDLFESMSYSGIHGLEDTTSIVSWLKTKKNLLSSMISGQPLESKVVTLKSELENIPFDIQLLNSESDIATSVGKALKASGKEAGALLDTKIKNERAKKAIDLIKKKTNDLVLLEAFTGQIPTWVVKSNDVPNWLPSSEDPWIARAQSQMETGPLGIFLELSQENYCMRDILPVLLAAVQSDSQLIFLVALNDNNIKPALPFLYLVDMLNNAGIRTKPIDVLLLNRKLLLPSLFIKLNGEGIKKKILVGPLALEAAKELPSSDANLLMEYPSAAVLNLANYNGKVLQHVIDSSADLFSAVSSVVRSTWLSGITINHRSRSLLFVHQPVYAQVLEKLKDSIEQMKVNEFKSEIPTGCDFVKRKIQDTPSILACISQLGAKTIPNNSNFDVPTVVYDIGTSSDIVANKEIGLGCLLIVIPYRSLAELFSLFNNQEEPDNVFIYANEINTTMDIIRHVKGREISVNGTAAITPTRNTLSWASFAESTPLHVQSGESRSSSLNLTLSASGCKEWHKLSNKQKVGKLQQLLACLNENPVFLPQLLSSHMDLVAQSTVRNQPEGVSGLVLINPAKIPTSDIVKAITACVLSERPVVVLAVNGKLSAAIEDALKASLPSGLVTIVNVGTYWEAISEARNLDLLWVIKGSELSTPLLRLPKSVAIKTLLINSANDGELMQNAEIVMSTAVRSCYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR07</accession>
    <name>A0A1D2MR07_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apolipoprotein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000660">
        <property type="protein sequence ID" value="ODM95517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR07"/>
    <dbReference type="STRING" id="48709.A0A1D2MR07"/>
    <dbReference type="OMA" id="YHLGACP"/>
    <dbReference type="OrthoDB" id="6728016at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF49">
        <property type="entry name" value="APOLIPOPROTEIN D-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904421" evidence="2">
        <location>
            <begin position="24"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="41"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="31792" checksum="6B8904CFFEEA2EA5" modified="2016-11-30" version="1">MNTQASFVVVALLAAIGWNAVNAHTMGLGSCPKVEPLKDFDMDKFMGEWYVIQKFATSSSCMKYNFTKGSDDKMRLVQTRQHFILDTIGVDHLYTYTGVLTVPDTDKASRMRVKFPLNIAGEADFVVFMTDYETYAGIFTCQKILFGHTKSASILSRQPTLDKVIVNQIRQKLEEEGVDPDDFSVVDQANCRNKEDTSLNVKIDDKTFSAKNVAGVVKKIGGAVGSGLEKAGDVLGSGISKAADVTGDIVETFGDKQNQQVAPNAPTSTKDLNELLKNAKVEENDAEWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR13</accession>
    <name>A0A1D2MR13_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endoplasmic reticulum membrane protein C16E8.02</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000694">
        <property type="protein sequence ID" value="ODM95244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR13"/>
    <dbReference type="OMA" id="IQFIGHY"/>
    <dbReference type="OrthoDB" id="2124888at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046521">
        <property type="term" value="P:sphingoid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026:SF9">
        <property type="entry name" value="2-HYDROXY-PALMITIC ACID DIOXYGENASE MPO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="DUF962 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G05310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21711" checksum="2A7C15FE5D1D5298" modified="2016-11-30" version="1">MGITDLEEQFTFYASYHHAFVNQLIHIVCVWPILWTALVFTQYIPIEAPISTPVHPANIALFTALFYAAVYVVMDKKAGSLAALLVLICLITSRRFYLTAEISYGVPAWQLAVLIHVVCWIAQFVGHGVFEGRAPALLDNVTQAFVMAPFFVLLEVLFHLGYRKDMQVKLWKNVEKELARLKQKKIGKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRS7</accession>
    <name>A0A1D2MRS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Adenosine receptor A2a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11077</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000646">
        <property type="protein sequence ID" value="ODM95608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRS7"/>
    <dbReference type="STRING" id="48709.A0A1D2MRS7"/>
    <dbReference type="OrthoDB" id="284782at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001973">
        <property type="term" value="P:G protein-coupled adenosine receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24246:SF27">
        <property type="entry name" value="ADENOSINE RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24246">
        <property type="entry name" value="OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="413"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="466"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="508" mass="56895" checksum="FC3999CC856F3153" modified="2016-11-30" version="1" fragment="single">IILFCWVAGAIIGFLPLFGWYNREGWERDPPGYCFFTDVMDYSYLVFLYFATIVFPALLMIGFYGYIYHVVLIKIRQKGTLAPQHLRRFSEQSRTGSLSCENRSATQVLRIMVSEKRREAKAAKKLGIIVLFFMLCWMPLYTINCIQAFYPKFQVPIQFLNFTIILSHANSALNPFLYAYHLKEFRLAMKNALMSLCGKLLCGLVNAHIEKDNPLGPMSRSLTMPSLGHVTTVPNPSGKVSIKFRKISRPDEPRSVQISPTNINSMIPTAVTTASRDNLLRTAGGTDKSLTSLSLGSDTSNQLLEIPLQVTTSTFTNNSPKNVHSNGGSGSRERKTAAHNPKVIQTNSRYHSSSSETIENCIITTTAPAGTTKVNNCQEVGDDREKITNTNDLQKYNASVNLVSEKENEKHSYIAEDEIKDEYREEEEVNEERSKLCSATETQPHSEFHPQHVRINSNEETSSESSHNDDDTKLVETSDVKGVPFSPLTKQQNGFDNNSGSNCISLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT47</accession>
    <name>A0A1D2MT47_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin H4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000561">
        <property type="protein sequence ID" value="ODM96213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT47"/>
    <dbReference type="STRING" id="48709.A0A1D2MT47"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904507" evidence="2">
        <location>
            <begin position="20"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="8"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="131" mass="14872" checksum="9405D553050001A4" modified="2016-11-30" version="1">MDFKTFLVLLGMAVAVTKAAPNSDHRVPTVRTEDELIRGLEGALSNGRTAVIRFYADWCPVCQADVHEFNKLIDKYPESSTKFFRIDVDQHPQLVSEYGIKAVPTYFVLRRNTAHSTFHGAQDVDNFLQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUQ6</accession>
    <name>A0A1D2MUQ6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kish</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_09848</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in the early part of the secretory pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the KISH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000500">
        <property type="protein sequence ID" value="ODM96820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUQ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MUQ6"/>
    <dbReference type="OMA" id="KVGFQGT"/>
    <dbReference type="OrthoDB" id="10034655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051523">
        <property type="entry name" value="KISH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009653">
        <property type="entry name" value="Ksh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13229">
        <property type="entry name" value="PROTEIN KISH-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06842">
        <property type="entry name" value="DUF1242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM96820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="7979" checksum="A8C1359B4A4180E8" modified="2016-11-30" version="1">MSALFNFQSLLTVVALLICTCTYIHSIFPSILDRNKTGVLGTFWKCARIGERLSPYVAVFCIGLAFSLLFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVV2</accession>
    <name>A0A1D2MVV2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">Phosphoacetylglucosamine mutase</fullName>
            <shortName evidence="13">PAGM</shortName>
            <ecNumber evidence="4 13">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_09865</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 13">Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13 16">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="4 13"/>
    <dbReference type="EMBL" id="LJIJ01000501">
        <property type="protein sequence ID" value="ODM96805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVV2"/>
    <dbReference type="STRING" id="48709.A0A1D2MVV2"/>
    <dbReference type="OMA" id="WEAYATK"/>
    <dbReference type="OrthoDB" id="1928at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000003">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000013">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000015">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016408">
        <property type="entry name" value="PAGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="18">
        <location>
            <begin position="50"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="18">
        <location>
            <begin position="105"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="20">
        <location>
            <begin position="210"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="19">
        <location>
            <begin position="302"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="17">
        <location>
            <begin position="454"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="14">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="16">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="375"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="498"/>
            <end position="502"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="507"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM96805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="539" mass="58107" checksum="38BBED890F7B6EAD" modified="2016-11-30" version="1">MASKIAARIVEAAKAHTRRVDKYIGYGTAGFRTKADLLDHVMFRVGVVSALRSKMVKASIGVMITASHNPEEDNGVKLVDPLGEMLEPAWEVLATEIANLPDDKLSESIVSLIEKSNIDLSTRSSVIVGRDTRQSSPALCQAVIDGIKAVEEDSEIADFGIISTPILHYLVVCTNDGGKYGDPTVDGYVAKLSRAFRTLIGEDNKRGNYEPTLIIDGANGVGAVISEKLIKALDKTLAVNLVNVGPPGILNHDCGADYVKVQQREPLNVSSDCGARCASLDGDADRLIYLYFDEAGMFHMLDGDKIALLFAEHFNDLLKKSQLNLKLGMVQTAYANGSSTNYATKVLNVPVTCTPTGVKFLHHAAQEFDIGVYFEANGHGTTLFSENAVKTIKDAASSGGNAAAQELAGFLNVINSTVGDAISDLLGVEAILHSKGWSIKEWDTMYQDLPNRLLKVSVADRNLVTTTDAERRVVTPEGLQERMDIIVAKFKDGRSFVRPSGTEDVVRVYAEADTQEHADELGKEVAAAVSELCSGNCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVY4</accession>
    <name>A0A1D2MVY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000467">
        <property type="protein sequence ID" value="ODM97166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVY4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="24275" checksum="B32985F764D89DE1" modified="2016-11-30" version="1">MPPPNDDEVDDFPNNDEVHDFPDDFFDNLAEALSGNYFYTCYCYSTSIHKDIFRLKTVKAGFTWALYLTIFTVMLDLGSELARLSISTDSENDIDIVLIAKDPKEGHLVDHISGLQNLWSGNEAQVFVHGQGQDKVLNGKQSNGSSSGSLSYFLSNAAYQILLRYMLFTVVCFGVQLLAALGSILYNLVLRWIIASYKNSLIAGLIRLRRVTGNGVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW26</accession>
    <name>A0A1D2MW26_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000469">
        <property type="protein sequence ID" value="ODM97141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW26"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="199" mass="22645" checksum="DF4497F9F190F493" modified="2016-11-30" version="1" fragment="single">MFHTFKCELLEEVVLKLCRADESNIKNLSNNQANSEGNKVVFKSNWKQDVSGVVNQDELDGIFRKAVGFDCEISENLRRRDLPRRRSSLLLKARNHPIYHTIRKIQGFTTVMWLQFMRYPLFVAALILLPTIQGAITIATIGNKPTGMAVGIVNNEMSNWNTGCSELDLNACDFSFLSCHFIKEMKKDDLLDLVNMSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXG2</accession>
    <name>A0A1D2MXG2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SUMO-conjugating enzyme UBC9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09174</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000437">
        <property type="protein sequence ID" value="ODM97494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXG2"/>
    <dbReference type="STRING" id="48709.A0A1D2MXG2"/>
    <dbReference type="OMA" id="TWECGIP"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000013">
        <property type="entry name" value="SUMO-conjugating enzyme UBC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="8">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18532" checksum="5FD4A6B2A5EB31B0" modified="2016-11-30" version="1">MSGIALARLAEERKAWRKDHPFGFVARPTKKDDGTLNLMNWECVIPGKKGTPWEGGLYKLRMIFKDDYPATPPKCKFEPPLFHPNVYPSGTVCLSLLDEDKDWRPAITIKQILLGIQDLLNEPNIKDPAQAEAYTIYCQNRLEYEKRVRAQAKVMAAVEGISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXQ5</accession>
    <name>A0A1D2MXQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000407">
        <property type="protein sequence ID" value="ODM97823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXQ5"/>
    <dbReference type="OrthoDB" id="10063592at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="450" mass="49576" checksum="6B75AD54DACDAA36" modified="2016-11-30" version="1">MRKSQPQRRLQYLLNETYMKIDELKELIRKEACITGSNSHDATVSRMFSRQDYLVTLCAEICSQQEKRNEATGTVQRANVRPSCSFAVPSSTVEQPRSTKSEKDDAKPDGSWYGSLDRSLAKKKKHQIIDKRRRHTKTIGSMAGLDVIKKSVELQPDEQYEIGLPAAPKITSTRSSIFPMTQHQHSQPTPALLPPQVGNWGYHMDGFDENKNMRPPLQQPPNLKPNVVPLPCRSLGNDSAFRHSGKSTKTWHETNLDDCNSASVATLNPSPSPSMLSSTRGSSRGSVASGMDTVDGGVARMTITGAPNESAEFTSKSSESSESWAGTGNEVTKPFEMSDYYKYSTKFRSRNSPVSEEGQSEPRSPNGLSSSSLSLAHSRHPSQIRQASFDATNGYRDANGNPSSVGPKLPPKQRRNQNKSISGSTVIYEGDMVNGESAKDVWITNEPTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY99</accession>
    <name>A0A1D2MY99_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DBH-like monooxygenase protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000427">
        <property type="protein sequence ID" value="ODM97625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY99"/>
    <dbReference type="STRING" id="48709.A0A1D2MY99"/>
    <dbReference type="OMA" id="EEYVGHE"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042420">
        <property type="term" value="P:dopamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOMON" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="177" mass="20504" checksum="13759D74BB390D86" modified="2016-11-30" version="1">MTMPTMDKQQDWTLIEASENKETSTTYLKFSRLFNTCDDEDYPISNDTARIIWSVGANDDVAYHGGSRGTKSMNLLMPQDEDFNPDDYLKWDLEIEIEMPKHHTTYWCQMKKAPQMDKTNHVIGFEAVLENELALNHTHHFVIYKCNVPEGSNADELFEEYVGHEGLTATCQWTNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYD7</accession>
    <name>A0A1D2MYD7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000385">
        <property type="protein sequence ID" value="ODM98063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYD7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="62" mass="6767" checksum="EDA941E3EF6C9978" modified="2016-11-30" version="1">MKNEAFGASIERSSDWNGETGIDSPINPMELAFPAFQRFKRTPDGCCSCGDHHCCGSMCHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ25</accession>
    <name>A0A1D2MZ25_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative AIM2 family protein C30D10.14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_08384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000366">
        <property type="protein sequence ID" value="ODM98296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ25"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ25"/>
    <dbReference type="OMA" id="FGFHPHV"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904769" evidence="2">
        <location>
            <begin position="20"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Dienelactone hydrolase" evidence="3">
        <location>
            <begin position="238"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="379" mass="42393" checksum="B9246CEE73124BE8" modified="2016-11-30" version="1">MKMNFSLAIFLLATLLAQSYSVVGTEDEYEHDYNVVEHPGPTVSPVQLEVEETVVPVEPGSDDDEEKEGDEEVVQTTTYPVFDEPPSSTTTESNTLPLTSTTVGTTTTSTTSTTSATSTSTSTEISSTTSTAPFLPPHQRPVRSDLASMPPPTGQEILVGNVTIYESAVTNDTFEDVMLISVHDIFGFHPHVKYISDRWQDMATAQWFQTFFMEIQSQLKIFHLPKTAKYLFNKDGFWGQIKVDLLNVMNYYRQTANITSFGLYGFCWGGKMIVYASEDKDFQGINAIGFVHPSRLVTSDANKINAPALLLPSNAEPDMVPFLQILEQRFGEGKSEHYRYEDMRHGFAGATSDFSNPDVRSRVEDVIEKLNIFFRKHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZA4</accession>
    <name>A0A1D2MZA4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000361">
        <property type="protein sequence ID" value="ODM98377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZA4"/>
    <dbReference type="OMA" id="IDVEMNV"/>
    <dbReference type="OrthoDB" id="10546903at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="68766" checksum="968804746630F4BE" modified="2016-11-30" version="1">MPAIKKRKMSAPNEEETTVAVKAEPIATRSASRKSAASAGTKGVHPLLIDHILETVFEHLFWPNSKYPNVEGTYVSIQDVRNSRLVCKQWNEAATKLYRRGRSPSMFGNVMPPHSSLKTYDLNMQSFLDVMKTSSLIPVQRYVIGANFFVKQNQRLMKDFMRICGPSATELRFYFDYTSTMNFTRRSFPDLKLPKLKSLLFNCGNYRGRNCSSQTYEIPYLVEVVLGAAERLQEFRFEFAPRDFKWQSVVVRRFAEIISKRIPKSVKILRLDMWLNDNHLNTLADTGLELQEFQFDCHCAVGKDVIKKFFERQSRTLRVLKILNSDPNCSVSVDFPRFDQLRQMELQGATISPFSYPDTFPKLETLNLSEWKTEKTVTQLLQLSKKANSLREIFFPSRFSQAGLVRKAAQCFPNIKSVHIAPSPDIAEALQEAFVYLPDIEELYVSFPFLLDNELNVDSLFSGVSELDCRRILKHRNFENVNVRDVQKKPSITNLKKLKKLVIDDSASDIILTDFSAHFSFMKMDNLKELQTSRFRMSSKYVDLLRNKLALKLTEDDYSDYSSDDSIDSDGWNSDSSGEELEIIPFLGFGFNVFFIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0A4</accession>
    <name>A0A1D2N0A4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08350</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000363">
        <property type="protein sequence ID" value="ODM98335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0A4"/>
    <dbReference type="STRING" id="48709.A0A1D2N0A4"/>
    <dbReference type="OMA" id="SHAFSYF"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="38"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="443"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="128"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="603" mass="66585" checksum="172458227BE36FF7" modified="2016-11-30" version="1">MAIRGMKTVTHSFVGLLQWGDYLSEGFTQTPDADANHYDFVVVGGGSAGCVVAARLSENPMHRVLLLEAGGNPHPLSIVPLTGSLLHNHPSADWQYATVPLNNSQFPLGDRKLPWPRGKMLGGCSSINYMVYMRGNPKDYDEWANKTCDPRWSYTNVEKYFKKMEDYHGSFNNHENFHSTNGPVTVEPIKYAPGLKNLLQAVKETGYRVRDLNAYQKEGFSPLEVMQKRGRRMSSYTSYIEPILKRKNLKILRYAHVTKIHLDSKLKATGVSFVRNGRTSYVTAKKEVIISAGTINSAQLLLLSGIGPQEHLRSVGIKPLVELPVGKNLQDHVMSHIGPIILNDTSTSFMPFRDLSLKSLVDYYSRGSGPLTSPMGMISVGVTSTSTSAGWPNILYIIGSMGVTYGSGEMADDVYRTGNHFTQLSNTFIGQAAHTAFVALGKPKSRGIIELRDKNPFSKPLIDPKYYSDEGNQDMLDMIEGYETIVKLYEKSDSLGRKLGARIVEIPSCAKYGFKTKAYYECAIRTPILHMFHPVGSCAMGKIGDADSVVDSQLRVIGTKGLRVIDASIMPTITNANTYAPTILIGEVGADLIKSSYVRNLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0V8</accession>
    <name>A0A1D2N0V8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000311">
        <property type="protein sequence ID" value="ODM98926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0V8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904827" evidence="1">
        <location>
            <begin position="28"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="38375" checksum="788C40E4A0F2B63E" modified="2016-11-30" version="1">MQPAARQYLRRCLTLLLWTIFFPSTSGWFYTAEDKAGDAEIKAEIMKNRQFPECNCLQKLRTNYFSDNMCGKVALCYWEIWNYKKVKAKAKNDNTYEGGDEEKCDKFLAQGYACLLGYPQPPKSKTICDDAIVSCNKALAKLLYDDCEELRKSRQLSKPQDIQTELVVDDMNLDLNQDENTIFQPTPKPEQTDRNNYYILSCPIVYRFPYFTIDLLFKHWDPTIEYDETTGLKEVAHMLPKFLREGINNERIQNFDALSLDPNLINWCNIPRNYICITDERDSDGKTLCNCNLCDSQTECNMHRTDGDCDFNLMAQNDELTAKGVKCPNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1M0</accession>
    <name>A0A1D2N1M0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000298">
        <property type="protein sequence ID" value="ODM99130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1M0"/>
    <dbReference type="STRING" id="48709.A0A1D2N1M0"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="70"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="28569" checksum="D4FB87E9358B9121" modified="2016-11-30" version="1">MIRVETPQEEQSLKKFRDLVQDLNQDELTDVLLLRFLRARDSPEKAEVQLRKALKWREESKIDSFLIWRPSKPVEEDLCFKYTGPDNEGRPVYWVPIGRWHVRQFLEQGYREDIQKFKYHILEYITNNTEKLGHHQSVVIFGIERLAYSQVLHLESMQLMFASFRDLEQYYPETIKTMYIVNTPWFFPYVMNILRPLLSPRTSNKLKIYNGDKTSWLTALRKTMPDESIPAEYLRETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N291</accession>
    <name>A0A1D2N291_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation initiation factor IF-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000284">
        <property type="protein sequence ID" value="ODM99392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N291"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904916" evidence="2">
        <location>
            <begin position="23"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="137" mass="13984" checksum="7A1A0A288FC121C0" modified="2016-11-30" version="1">MAKLAPIVIVVLAAMLIDIATAFGGYSPGYAGAQGGFAGGQFGQQEGSQETHNDKNIGFNYGKKQGSSSNFKNTAAQAGAGYGAAQSQYPGYYPPQTGWGPPPPNPGWGSPPPTPGWGSPPPTPGWNQPHPTPGWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N389</accession>
    <name>A0A1D2N389_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Broad-complex core protein isoforms 1/2/3/4/5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000257">
        <property type="protein sequence ID" value="ODM99743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N389"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048666">
        <property type="term" value="P:neuron development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF99">
        <property type="entry name" value="BROAD-COMPLEX CORE PROTEIN ISOFORM 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="36"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="512"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="632" mass="68899" checksum="7D8C4B482E5C45C1" modified="2016-11-30" version="1">MSGTGGEMYSLKWNHYHTYLTSGLAQLIDDSEDSMTDVNLACEGQFIQAHKLILSLCSPFFKQLFRVNRMEKSNYINVVLTGVKFKDLKNILHFIYHGEVNVGNAELNHFLQAAEVLQIEGLAGGVENNQQETVLTTETKKPTASVLAPQGPPPPAPSTTTSSLITHNNGAPPNKRSRLSVSTSSSNMLNTPLSTSRLGSQISQTSHRSVTSMSVSAGGMSSNVIIESGNQTSTIASDPLENDEGGSIDECGEEMISLDAMKSEPIAVYTITENNAESDEIHTGTRNPTTRNHGGESDGMLYDFESHVIQTSSNVGAPGPSSSSAIMRPRVTGVQKADKRIVENIGDDSESDDLEILSPLPKQLSVNAGQRAGSLESPSSLLLKEVFSLAAESPYYAGSGHGMIGVGVMDDSLSESRPVCQFCGKAFKNRNTLNNHRSVYHRDETRRTRPSFNLGESNSEEYKVPDTYPPLDNFQMRCKTCGENVPSDSFQTHGCYSSQVVGNQAIGIVQPVQCTICLKTFKNRNSLKVHKSTYHRPKDTAPSGMRLSHLAEIITTSSPPMLVTTESSVKTYPSAASSSHQTQSMIRNECNDNKSFQLPMYAQPHTLLAILHQQQQEQSYSEFDNEEKKPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3L1</accession>
    <name>A0A1D2N3L1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phytanoyl-CoA dioxygenase</fullName>
            <ecNumber evidence="2">1.14.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Phytanic acid oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phytanoyl-CoA alpha-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.18" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000252">
        <property type="protein sequence ID" value="ODM99842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3L1"/>
    <dbReference type="STRING" id="48709.A0A1D2N3L1"/>
    <dbReference type="OMA" id="FHHSKIN"/>
    <dbReference type="OrthoDB" id="2328924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048244">
        <property type="term" value="F:phytanoyl-CoA dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001561">
        <property type="term" value="P:fatty acid alpha-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047128">
        <property type="entry name" value="PhyH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21308">
        <property type="entry name" value="PHYTANOYL-COA ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21308:SF1">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="31879" checksum="568DC18B51FD31DE" modified="2016-11-30" version="1">MGFLSETQKQFYKENGFILLDNVFSETEIDQCSVAYDELFELKKSQDSNMEATWKGSWNENSQNKSVLSIHNLQCHSSIFTKVLMNDNLLDAVSDIIESPNILLHHTKAHIKPPEKGARIGSLNDLNLQDYHYFPYKNDSLIAVFVHLDDSDPENGGLAIFPKSHLMGPQENKSDVPTNFYVDQEKFALSKAHPVIAKKGQVLIFSYLLVHGSFPNVSTRNRRMLLIQLMSAEDTPLNQTHMSPCHGMVLRGKNVRRNADLSKRHETDEKLIVEKKIPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3T5</accession>
    <name>A0A1D2N3T5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_07072</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000269">
        <property type="protein sequence ID" value="ODM99595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3T5"/>
    <dbReference type="STRING" id="48709.A0A1D2N3T5"/>
    <dbReference type="OrthoDB" id="302728at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="11">
        <location>
            <begin position="160"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM99595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="396" mass="45875" checksum="114C572B6641AF4D" modified="2016-11-30" version="1">MKGDPMKANSHVPGYVVNGFPFVILIPSDLPTHLRLIRGLHQLIVRERNQVVERGVEPTWALFIRLLISAVVCYCLCVWKRELTTIEKWIFPEVLIPFAASLLVLVATALMCATIKMDPGVQPKKSEEHQQMESEYYNKNRKGPTPVIRPIVYYGHRSMGNYCFDCKHFKHPRTIHCKYCDRCVVRHDHHCNILGTCVGIRNFAFYFYFLIFSALFYIYIFSFSVGILVKGLREKEAVKAFQSVSILWILPLTVVVLLISNLGHILVFPFIYFYITAHDKTAHELFFVIETQGRHYKCYKVMKALRGERKRSCCKGLLNVLNNLRVYLCSPVPPSLLDEDNYFVVCDLDEVLTWDKLKQSEATGPKKSKSVGQLPDYKEDEEFKLMDTRKISCCYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4L9</accession>
    <name>A0A1D2N4L9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Venom serine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06462</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000223">
        <property type="protein sequence ID" value="ODN00218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4L9"/>
    <dbReference type="STRING" id="48709.A0A1D2N4L9"/>
    <dbReference type="OMA" id="AIANNMS"/>
    <dbReference type="OrthoDB" id="8248404at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF472">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CPVL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="517" mass="59355" checksum="A6CCE1B961FB753A" modified="2016-11-30" version="1">MGYHNNIIISPLLRRRVFVYSLAKNTKKDDMDIPRIYKHFYRIFISKESWLFGALVSSCLLLLTNVPLAEGQRSTPGRTTPVEESAAVNSGDRLILTPFLNNGSAREGRELSRVKNMASTESYSGFLIVNDTFNSNIFFWFFPAQYQPKTAPIILWLGGGPGVTTLYGLFNANGPFFVDDKNVLHRRDSPWSLTHSLLYMDSLVGAGFSFTEDEAGYARTVEDVSRDLYTALVQFFQLFPDFQSREFYIAGESYAAKYVLAVAYKIHKENLKSPFIPINLRGLAMGAPFIDPYNQLDYGNFFYNIGLIGEQEQSFFHELEKVTLDLIRKQRWADAFKVGESLMVGYPLVAPSYFKNVTGFRYIRNYHQAVGPEDRHYFINYLEQDHIRRAIHVGNQQFSNFNDTVYYAMHEDVYQSAKFLLEELLDTDNNYKVLIYTGQLDALVPHTTVTTMIKSLKWSGSPEFHLADRVIWRVNNDVAGYTKTVKNLVYLIMRNAGNVAGYDQPLWTFDMVNRFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4T3</accession>
    <name>A0A1D2N4T3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="6">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000222">
        <property type="protein sequence ID" value="ODN00231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4T3"/>
    <dbReference type="STRING" id="48709.A0A1D2N4T3"/>
    <dbReference type="OMA" id="DENQGVN"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000001">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000003">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000004">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0041">Annexin</keyword>
    <keyword evidence="3 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 6" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="372" mass="40496" checksum="2F66225E6101452B" modified="2016-11-30" version="1">MLTGTSRTRTSATAGQTAYPGQSAPGYPVQAPYAAAAPVSQLGSAPPAGAYGAGMQQYQETPTILEGPFDATADAQALRKAMKGFGTDETAIINILSKRTNNQRLQIAQAFKSGFGKDIIKDLKSELGGRLEEVVLALMMPRFEFLAKKLNKAISGIGTKEKTLVDILCTATNMEIREINAAYHRLFNKSLEKDIQSDTSGHFCRLLVSVNTGARDENPAADPGMASQDAQALLQAGEKKIGTDESTFNMILARRSFPQLRLMLHEYERLSGHSLEKAIQNEFSGDIETGLLAVVKSARNRAAYFAERLHDSLAGMGTKDDDLIFIVVTRCEIDMENIKQEYNKMYHKSVAQDISGDTSGDYKKILLGLIGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4Z8</accession>
    <name>A0A1D2N4Z8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphorylated adapter RNA export protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">RNA U small nuclear RNA export adapter protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_06549</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PHAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000231">
        <property type="protein sequence ID" value="ODN00135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4Z8"/>
    <dbReference type="STRING" id="48709.A0A1D2N4Z8"/>
    <dbReference type="OMA" id="FREERAY"/>
    <dbReference type="OrthoDB" id="20573at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006408">
        <property type="term" value="P:snRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1440">
        <property type="entry name" value="PHAX RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039047">
        <property type="entry name" value="PHAX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019385">
        <property type="entry name" value="PHAX_RNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038092">
        <property type="entry name" value="PHAX_RNA-binding_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13135">
        <property type="entry name" value="CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13135:SF0">
        <property type="entry name" value="PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10258">
        <property type="entry name" value="PHAX_RNA-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Phosphorylated adapter RNA export protein RNA-binding" evidence="12">
        <location>
            <begin position="340"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="107"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="223"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="280"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="507" mass="56774" checksum="F2F8B6999D1D4BA7" modified="2016-11-30" version="1">MMDLEDGELPSSDNEGDGSEMPEQTNYMPIEIPDDEDYVIVDRPKPSILSSSSSNTPSSGSMSHPPPRHQPPNQSYFEFVQTNSSNMHGSDLGQKAYYKDLGVSDLLDSSEKDSSSASDSDTETRNDGKRFRMTSHPQIPVNSGSNASVPFGGGGTTFGFAEAPTTNSFQVNRTPTDFASDSFAQAAEAFRSEAAKFQKERKTNTVWSSVIQEEQISTIFDRVKVTGPADVEIERGPESYSFQRPMRQPRPRRPSDSSDISSEGLSDNALHYLRDGFSYDDDETEESSEHALPKSFTSSSVSKSSASRKATKRKRERQKYKRKLINRLKKMKALDLAHYMGNKLHEEKVTLLFRSIEILGKENCVRIFLKTLKIERRGGVMVKNQERRRTGGGVFLYLIRGDRRFPKSQIDLIFREERAYHDKVRKKKLVGKRLKKKAKLEAAKAEMEANGMRDEDESDDDDTTVPNPDADGTDTGQFGDDSTQESSIHDKDITEELGSMNCDGSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N567</accession>
    <name>A0A1D2N567_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cysteine desulfurase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000209">
        <property type="protein sequence ID" value="ODN00408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N567"/>
    <dbReference type="STRING" id="48709.A0A1D2N567"/>
    <dbReference type="OMA" id="ETRAGCS"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686:SF1">
        <property type="entry name" value="AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686">
        <property type="entry name" value="SULFURTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="70"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="684" mass="77089" checksum="7C9F35319AE42C84" modified="2016-11-30" version="1">MTNILTTATATAQSYIMQDKEHDSIHKEIIRRDPELKIIKNPSAITRYLDHEVIGGHQEFTGPFGKRRYVYMDYTASGRSVSVIENFMANYVLPNYANTHTTTSRTSLQTTLFRDQARDIIRQAVGATEEDEVIFCGSGATTAVHKLVHHCLGSKKKPRKIIAFVGPYEHHSNILPWREAASKVIQIPLDIYGNLDVNFLHAKLKFESEKRSKKDKLLVGCFSAGSNVSGALTDDVLITSIMHQYRGFAFWDYAAAAPHVKIRMNPECGDVGANKDALFFSGHKFLGGPQTPGVLVVKKHTLLNPVPHGAGGGTVLFATRKNHQYLEDIHEREEGGTPDILGSIRLGLVFRMRNCAGINLITELESKYCRKALEHWSIIPEIHILGPSECPRLPIISFMIEHPNSGYYLHHNYIVVLLNDLFGIQCRGGCMCAGPYSQYLLGIKDKLASKYESALQQSHSKYKTNHKCKDNQTIGILLKPGFARLAFSYHSSPVEVDFVIKAVALIAREGWKLLPLYHMSPETSFTFNARKSTNTVSLAHFDAYLSTMSYTTGTAPFFPVKADPMDYNNILDEATSIFRKTSKGYHLGQAVQNEFDELLNEPEALAMKWFLTPLDSFILQMTAKSQPYIRSRKVFSPVKGFDNSFNLLAYKASIPRMIMRVWWKDCSHENLRRFSNSECCVERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5H6</accession>
    <name>A0A1D2N5H6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4789 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000215">
        <property type="protein sequence ID" value="ODN00315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5H6"/>
    <dbReference type="OrthoDB" id="6328618at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031993">
        <property type="entry name" value="DUF4789"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21177:SF4">
        <property type="entry name" value="IP06524P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21177">
        <property type="entry name" value="IP06524P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16033">
        <property type="entry name" value="DUF4789"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905065" description="DUF4789 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4789" evidence="2">
        <location>
            <begin position="129"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4789" evidence="2">
        <location>
            <begin position="368"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="482" mass="53252" checksum="D0B9678819C6CE8B" modified="2016-11-30" version="1">MISKATVSIFFIVIVLIIKAFAETNSTSKSQVISERIITNLKDVINGVPIDYSYNESDTIPPAGLISVPGCPKSDEGYPWLYFGSPPKCFLTGQRGPCPADQSLFVELRTPFGFCNCDCFEGTQSSVKATPDQDRFCTALLQEFVYMPALEKCFPIFDQGPCAENEWLVKVAENVNGTNAFAKCETRKCPPGQAPVGEDKDGKTSCFGRFSVYASPVSIPRNKCKSEGMGVPSLQTDELFTMAQLGTGTLITIFVILTFQSFTEAKSVVSEPTLVNERIITDFNYVFDGAEVDFRYNESGSRMVSAPGCPKSDAGYPWVYYGSPKKCYLAGQPNNQCQADESLFVKSESPSWGFCNCNCFEGENGIRNKEQDQFCMGRNMEFVFMSKLGKCYVIYEQGPCGEEEWLVKIVNGTKEFAQCEKRKCPVGEIIYAENDEGKSNCGPRYAIAAGVAVSIQRNQCESDGMKYSELLQKCVTPFSTPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5M0</accession>
    <name>A0A1D2N5M0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">F-box/LRR-repeat protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5M0"/>
    <dbReference type="STRING" id="48709.A0A1D2N5M0"/>
    <dbReference type="OMA" id="LCNRIRY"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22115">
        <property type="entry name" value="F-box_FBXL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000042">
        <property type="entry name" value="F-box/LRR-repeat protein 20 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000060">
        <property type="entry name" value="F-box/LRR-repeat protein 20 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="424" mass="47158" checksum="19F63019D76457E5" modified="2016-11-30" version="1" fragment="single">KTRVCMEEEGLINQKLPKELLLRIFSYLDVPALCRCAQVSKPWNLLALDGSNWQKIDLFNFQTDIEGAVVENIARRSGGFLKKLSLRGCQSVGDNAMKTFSEQCPNIEVLNLEECKQITDATCISLSRNGRKLQRLDLASCSNITDESLKALSEGCPNLTHINISWCDNISEKGVGLLARGCPKLRHFIAKGRMFVDNESAIHLATQCPLLEVVNFNYAAALTDEAIQRLAQNCLNIHYLCISGCPNLTDATLLALAQYCHKLTTFEAAGCSQFTDNGFQALARNCHYLEKMDLEDCVLITDNTLTYLAAGCPRLEQLTLSHCELITDDGIRQLGMAPCAAEHLTVLELDNCPLITDASLEHLVSCHNLQRIELYDCQLITRAGIRRLRNHLPNISVHAYFAPMTPPPPVGGSRQRYCRCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N691</accession>
    <name>A0A1D2N691_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000188">
        <property type="protein sequence ID" value="ODN00751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N691"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="97" mass="11322" checksum="ED045F140864F855" modified="2016-11-30" version="1">MADYDVLQECLWLSKLILIKLKFQLPTNTKQIPTKLLTQHLVKALKSSYPQNHPMKATNLGQDVVKTVSTEDKSVKVVLLFVVRRFLRGERRERQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6F0</accession>
    <name>A0A1D2N6F0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mab-21-like HhH/H2TH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000194">
        <property type="protein sequence ID" value="ODN00655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6F0"/>
    <dbReference type="STRING" id="48709.A0A1D2N6F0"/>
    <dbReference type="OMA" id="GWNDEQP"/>
    <dbReference type="OrthoDB" id="6112914at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046906">
        <property type="entry name" value="Mab-21_HhH/H2TH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024810">
        <property type="entry name" value="MAB21L/cGLR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10656">
        <property type="entry name" value="CELL FATE DETERMINING PROTEIN MAB21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10656:SF69">
        <property type="entry name" value="MAB-21-LIKE HHH_H2TH-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20266">
        <property type="entry name" value="Mab-21_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01265">
        <property type="entry name" value="Mab-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mab-21-like HhH/H2TH-like" evidence="2">
        <location>
            <begin position="520"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="729"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="909"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="964"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="991" mass="114669" checksum="B0ACE454780AA056" modified="2016-11-30" version="1">MITKGYVRLRCVDEPVIFRKPLDVPRSSSSDFGYAHEPVYNKPYSDGVSEAMSSDGSPIHSGTTSDEDDAFDKEFRENLKNAKPFALQSKDKLTNKTSNELNGPSTSKAAFSNPSSRSKAPRIQIPVPHFESNVRYNILSSLFVSVNTIPMSLFTHATTPVLEGSYPMRPFDSLGSLHPYTKPGRILNHNHHSRSSPSLTDTSRDSQSPFKDMSSAGSGYESISISTRSRASSIASELVRDKWQKLNLKKLWEFGKKTRKDEIQPGVRYEPIPDNCYSEIKYEFSYDDADDDDDDEEEEEESSGEENETDDDQPYGYLEGGKKKKRRNDDEDYEMRFYLNSLQVSSNTCSEFHYIAPQISIPPSSITQGVVLGTTIRCPLPYRFQKEHEEEDDLDMENYYVTHTFTPSLHSKSWPKGLYFRFNQQIFSIIQKQGTRGEMWPSRAQMEQIELSGCNAIPLGYRSMDFFNAEQILEWELNFQEAEINLLNSFRCPQWRAYMFAATIFRAFIAPLGPQGIGLEHIRNILYFMCHDDFSGWNDEQPGAHLKAILDKLFFFLSKSNMPSFFIRSRNLLQSIPEQNLRFVQGHLNKIRENLIIYSIYAFRNLMDVRKTKASYSFPNFQNLFEMLTVPEGELLKIQNPVLQMEKDQEDEKLREEAKLRAKKKMKGKKRHHDLLHREESIDKEFFTTVSTIHQEKQARAHHHHKRDKLNEKLWRDYRKYESKLKIERQKEKEKLKHDPDHRLPEHERRKSIDLKKMPMIREQFTPFRLLLIIQFFIKQFIEMAEKAYKMKSYGPATMYVIQVENLCEIVEDDKYKETISPFQDDDLDEYREKTLRLRALLARDSHQYILARLTVPPSSPSGRYTSEPMSPTLGSFPTFTNNWDLRKLPTPPSSEKNIQPSGKVLQKPNISSTLQSLPNQNPEPTIPPTLPPVLPSPTRVPVRRQESIKFVSSEPPATPPRPRSSAPPSRSVSRQSINLSFDHGEDSTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6P8</accession>
    <name>A0A1D2N6P8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Meckel syndrome type 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000188">
        <property type="protein sequence ID" value="ODN00755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6P8"/>
    <dbReference type="STRING" id="48709.A0A1D2N6P8"/>
    <dbReference type="OrthoDB" id="10263520at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF4">
        <property type="entry name" value="TECTONIC-LIKE COMPLEX MEMBER MKS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="382"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="919" mass="105714" checksum="4A3210B97F563936" modified="2016-11-30" version="1">MRRFFGRSSSRKEGDDNKEEENAEEIPSEETEKLETHSKEKKGRKQVVSTESLEHEIKNFGEGDAGKDDKSRRGEDDRKISTALRNGRTDRRSKVNESAESEEEIENEPSRPSKGQGVSTVASDSDTINSPEAVRKKEKVPRQVVSNQRKEKVRAKEKVVKKGKSQAKRQPEILEELGADPRNESEEEVTKFINKKDLQHLPRVEPGKGGNFFATAYNYYDKPVGHLKVRARLLKYPTFSNQNGWPGDFAVIDDRTFGWQEKVFSKSEVKRYQKLENCTTEQEKRYQEEINHPDALGNFLYSYVTSDSYVLKKKLKTLIRRCPVRKEKSVSRLPMDFKLTNSDGESTDIDLENEMIDDDLTSEDTIDFDEPMSSSTPKSKRKQADRAEKMIKMEKKERERKEKEVQDLEKRNRKLQEAKEKKTKDDERKRNAEAMKAAEKKTKRVEEGQEKENERKEQYMKKYNYSKRPSLPLGARMRSVQMSPSPRKLGKKSSARRDSQFSPGHREDKTSLDSKNGDSPALKFKTKRKIGHEYSSGSGDVERYSFYHGRAQPYGKGIIRTQRGPKGHRKFKDRLSYHDGQTMFIMASIPYVSRKRREIIVCMIQNVPHLGTLIFKPSMGYRNIEAKRNHVFMITSELDSTETTQQKEFGVRIAKGEMAGLDYAKQKSAIVEELGGCFDVVPNNELRLTVMGEIMSAEGFESSPISIYYLVEIPKGWRNDSIHSNIEGITHTCFTNGDSIANFSHEFSFQLAFSMDSIEESDCFPTPVIVLMVVSMNHPSPRILYEGYGYVNVPMIPGRHSVQVRTWKPRPRTALEKMRETFLDITPSLHDMKFAHVSNSQFEDNRKANLVGLQTTPSGSVKLRLHTIHQTPRVFKEQERKLDLLEKMSSATIIRSVHAVIDAFQRARTKALKLKTQYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6T8</accession>
    <name>A0A1D2N6T8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pogo transposable element with ZNF domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05698</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000178">
        <property type="protein sequence ID" value="ODN00983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N6T8"/>
    <dbReference type="OrthoDB" id="10032537at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057618">
        <property type="entry name" value="Znf_POGZ/Z280C-D-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23226">
        <property type="entry name" value="ZINC FINGER AND SCAN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25429">
        <property type="entry name" value="zf-POGZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1287"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="741"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1195"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1491"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1678"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="630"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="741"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1492"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1511"/>
            <end position="1520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1754" mass="195177" checksum="E939134D09FA6AEE" modified="2016-11-30" version="1">MVSETSSEKVVEVSSKQSEANSTEPSEMEKSKDDTDSASKQKGIQNGGASPTNDVHNDGDDNSELESSRSQNGNEGEEEEEEEIVTPNGTLVEHSSMNNGGASHSPVMEERVYNEESNLSAMEEHFGVPRQLEEDYEELPEPITMKEFFYRMDLETNDVSEVVSDLTTRVERGEFTSCEHATPTSPCTATPPFAATMDPESHTQALSQTSGRMTIVWTEADSRLVKSKTDEFFEDRRLGKRFKKLPQNPKVFMSVPPGSLSSNPRENGNDEQEEDEGFMVSTTTHVDSPQDDAGSITQDEGESNTSLIEPMEVDLEGESGETEPSNKSTANEKNKETGGHSDSDEDRPTIFVRNFAEITEQQSDDEDDDIVILDPSPKKNRGGDERQTTAGPKTYQKKTGPPKKQLSDFITFDDRAATVEMVVEEKVDAVISEFISKKQEKRDSLREGAFALRKALLERRKLRQEKANSSLMQVPITMTPSRPRLATPIQVSRPRGPAPVHMQQSIQPNYQKVSMPGLAPLSIIAPNGTTNVPISQFQQANTFTQVSSTSGLPRMTTAANTNNQTVNPGGMQQLGSQLFFDSTKGLLYTVPNMNQGAPHQQNVPQANNQMNPANAIQPQLQPQPAQVRAQPPPPPVRIRQPIPPPRPVAAPRMQRQVYPMQNTTVRPQQMLIANQNRLQRPTQINVPAALSQLQFNARLAAPAQAEPSRMPTAQVAQNSQRSLLLSNTANRPVLTNSLQKMNSAPNIQRSKPASNPINSNATADSGLTAGTQRPVPGTVEENEAEPQNKTFPSLVVHVKTCLKIKPSRQMNAKSRSDLDAKVKSVLIHTPAKFAEWMMRRGLVKLEHKCIYPHHQALKLGMYSDDTRQPFSGGYVWTSECCPERQISIFSGSIFEGSKYPPGTVLKLVYHWSCQTPANNILQWVKISSFYLKNFFTLLRAICISYLHEHCPILGGEMKFVEIGVITLGSSAETSRGVKSVNVEILGVFDPSTKIIRMKVINSLQGLSKDKGKFGPNEQGARAFQILWPLTHWVDKRSTLLVDGIIDKTLFHELGFKNIQQCGENAPKNAPTNCNVMNYLRQIVPKMFASTLSVLSKSIVQQFLDELSWRELYGLTVLQSFENMLDHIAEMTKWNLNGGLIPRLNKVSQNPFADWSFTKQTRRSPLNTIPMTLRNEAGIRECIQYILKDESANQAAISTTTPPPSVPTPTATVAPKPPAPAPAPLQLQPLTMSGEKRKIPETPPTPRQNKIAYYQKSAKHITLEKYYYGVSTIRTTKSWSNTPFNSNIKCPLCVRTFASSREIIRHIAAHVAGHPKTAENSLCACCLKAVPSTADHRRDVHELVDCVHPCHFCQITFTTEMELVIHMWDLHVEAEAPYVCDICDFASSFHCDVIDHFNERHGDSCYVMCPYCLKVLSAKSFSFLKTIVVHLQSHQLKRTKKCTKCILSFGNDIDLRNHMAAHASKADLGNAWLRTTRQFPLKILMPTPPAIKAQSSSNFTDSSLQKSKKRKLITEKKRSPEPKSTLNTPFSVPLPIDPTEKFAGSRYKITLPDIEQGKAICSECKVDIMTPNHFIGRISCTKCRFTTSCRQAMDIHHDANHQPNSVSIRPILPTRREKMLNDPLVCKCGYLSRSPYKLADHLVRCERYTVYPKNRTPLYTEVMGDDVPPSLPVQHLLTISETNSKPSSSTNVTEEETTTDKTDEVDGFLPFSMNTSLEALSLPPVLSPSAPMPDSPFGEISGFEDNVNALLQDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8N4</accession>
    <name>A0A1D2N8N4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease snake</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8N4"/>
    <dbReference type="STRING" id="48709.A0A1D2N8N4"/>
    <dbReference type="OMA" id="ISADEKC"/>
    <dbReference type="OrthoDB" id="6339452at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051333">
        <property type="entry name" value="CLIP_Serine_Protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260:SF136">
        <property type="entry name" value="GH08193P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905226" evidence="1">
        <location>
            <begin position="19"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="108"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="367" mass="40548" checksum="3A6ACA7B61C11B44" modified="2016-11-30" version="1">MIIIKYAIFLLTSGLSATTSNPSCNLENDYKGQCQDIRTCPYQVGRLRVGAPVKKCDDSASDVCCPIQKSKSEEKCEEWRQMLYTPSSYDQPKHERVVCASESAIRWTLSGTTAYPFEFPHVVALGYGTNLTTLKLACGATLISEKYLLTAAHCVMHRLGKPSYAILGDGTLDPRVAPGNPYQKLVFIEEHVVHPKYIPPFIYHDIALLRLSASLDLNRYVLPACISTPLKAPRRNSNVEACGWGIRDDETTPTNNNIMQLQVANISTIGQGTCNKIYEDKPDKNANNMDGLLKSQFCATGENEDICRSDSGGGVFLREEQCLFHIVGITSLGSTKCGLASPTIYTNVASYQDWIESIVWEAGEEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB21</accession>
    <name>A0A1D2NB21_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="13">HMG-CoA reductase</shortName>
            <ecNumber evidence="13">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_04217</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:15991"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="13"/>
    <dbReference type="EMBL" id="LJIJ01000111">
        <property type="protein sequence ID" value="ODN02449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB21"/>
    <dbReference type="STRING" id="48709.A0A1D2NB21"/>
    <dbReference type="OrthoDB" id="310654at2759"/>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3270.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.420:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.770.10:FF:000002">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0521">NADP</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="231"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="757"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="764"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN02449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="830" mass="89155" checksum="331D7EB57D90F6CB" modified="2016-11-30" version="1">MSISVTSYYKRNGVCARRRKSSVTSMKSVSKSYSSPNNYPLSYGFRGLFLMAVVSYYSRAFYPIEEHNGVNTIFPSKPNADSIFGTLEAYGFISFNGTKITVDAFRWISISVDQLVVLSVAAALTVRYLFFDDKADGFRTVSEESTITTTTTVNTVYMDSGISAGATTAQTLTNNVIGITACAPLSSANITTSAPVPTPSQRRRKMPVNAKEIEILLNRNKLCEAKNNMSDYQDTCSSPDSGISKSRPSSGSVTPITFSIGDHSESDDEVDSEDSGLTMKTENAETQTMSENLNLSRKDETSGRWTGTPRPLEDCITLYHSDDGVKQLSDEEVINLVNAKYIPAYQLEKAVQDLERGVAIRRKLSCMQKDVKGATPDIPYKNYDYTMVQGACCENVIGYIPIPVGIAGPLKMDGKLHYVPMATTEGCLVASTNRGCRAFMPNGVRTRVVHEGMSRAPVVRFPDAMRAAEAMLWLGESENFEEVKQRFDASSRFARLTKIHPRIAGRYLFVRFVAKTGDAMGMNMISKGTEMALQVLQNHFHDMEILALSGNVCTDKKPSAINWLEGRGKSVVSEAIVPANVVENVLKTTTAALVELNIAKNLVGSAAAGSIGGFNAHAANIVTAIYIACGQDPAQNVCSSNCMTIMEPSGVDGRDLFISCTMPSIECGTIGGGTILPPQAACLEMLGVKGANTVNPGENARTFARIVSAAVLAGELSLMSALAAGHLVRSHLKHNRSATLLSAIALEQQAANTKIASGTTIPDSQSHTSTTSSDKVAQSIKSNLAPVSSSATLKPDSAGSGDMIKRSLSSKSSPVITTMEFLSVPDCKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB48</accession>
    <name>A0A1D2NB48_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000110">
        <property type="protein sequence ID" value="ODN02471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB48"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="164" mass="18740" checksum="E04DF7F944E13B7F" modified="2016-11-30" version="1">MLILVNYMRILVGRNPDERNLMEPGFTETLAYKPARNQAQAQIKAGRKAKIKRSCYIGRKLESATPALLCAFYPPGVDNLYRAYQIFVQAGIYFVYLNEFSSMNYASRVQDRLKVKGETALAPDEDNQFEPMELAQALRILLLLLMLLVLCSICFILEVIYNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBP9</accession>
    <name>A0A1D2NBP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sister chromatid cohesion protein PDS5 B-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_04162</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000108">
        <property type="protein sequence ID" value="ODN02505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBP9"/>
    <dbReference type="STRING" id="48709.A0A1D2NBP9"/>
    <dbReference type="OMA" id="ECYQVRE"/>
    <dbReference type="OrthoDB" id="200660at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1222"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1244" mass="142021" checksum="48147788324F269A" modified="2016-11-30" version="1">MHMATRTRSTRKRTVKAAVEETTPPVVANEEPDGDYDLFPTPSPPQSSVVAGSQSSKSSNTTSLSSPLEATRQDSTPLQSVFLGSMVYPPQCKEITDELTDSELIRRLKVLSSSFQAMSQEVVDREEYLPLCLHLASDEFINHSSRDVQLLIACCIADILRVYAPEAPYKEDDQIHAIFMFLIRQLEGLKDPKDPAFKRYFYLLENLAYVKAFNMCQDLEESQEIFQCLFHTLFSTVSNEHSESVKTFMLDLLCPIISESNEVSAQVLRVVLSSLVPTGKPHNKSTQKLAKELIIRCSDALEPHLQMYLNQAVVCDLDQTEEDPLARSKKVYELIYELNSICPNILLTVIPQLEHKLKCIDESERLECVSLLARMFSGNGSKVAQSYPPLWQAFIERFNDVSVKIRIKCVQYSMHFLLNHASLRKDIIEALRVRERDTEDSVRFEVVKSIVATFKQNPEIVSQSEDLLGYVKERCLDKKWKIRRESFQGLGLIYKKTLGIENLPDATKKACSWIKDRVLQGYYLTTIEDKILIEKLLNTCLVPYHLEGRDRMVKLFWLYATIDENSSKAFIEIQKNLLIMRTHVSELLKLIRDHKNIPDYSTKLNLRINSIAKFFTEPVKSSEFICKLSNDLTQDQDLMNTMESIMDLKTDCTTCADGVKSILKKLGPPVMTNLYYNTIKTLLERVASLLVDGEAVKEVITLFQEIVIGSSDFTDKFDVQPNVLMEKGSSLISVLAYVFPHHFDDGQVLKMLIEFLSNENLSSEHRCNILSALMCIGESASIDIHHPSLIKSLIHQLKEMTLNGTPRQAKLAVRCLFVHLKEEVRDQIFAQVVKALKVNLDPDNSMYRTAIIALGHIALLMPDHFQAEIRSIVTQKMVKELLLHPPRKPEDQTEIAGEWCKEDELPELTQCMLAAMKSIARWLLGQKTDLSSAAKTFKMLTAFCPFSNAENSWLRLTAGNCMLKICQQKGVGDQFTALQFCILSKLMNDEVIEVRTQFSNKLYKGLTRGAPQKCLPLDFMGFYALGGYETDKKLKILIKNHMIANVNQRRGYIKLLLLHAADKAADQLPLIMPDYMLVFAVPILTHSPHFTTYQDIQQLKAVKECLWFIMEPLIIKNDNFSYGFYGKILENMKQYKNAVDPDNEEANRRMYTICDIALDILHQRSPSIDKLVDYITLSEPRIPSMYFKRHVDPNFVNRFVNLPAELQEANRKRPVGVNELTRQSLLIEESEPGTTSKAKKRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBT5</accession>
    <name>A0A1D2NBT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000098">
        <property type="protein sequence ID" value="ODN02709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBT5"/>
    <dbReference type="OrthoDB" id="272500at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18906" checksum="F2024F360608F1B0" modified="2016-11-30" version="1" fragment="single">MEVRNNCPNETHLLKRKSGGSKTETEKTDTQSVRNGGTRVHEGESSTQGLFSTGILKQLFLSDLHESLKSNAVVLVLITRIVALVGWTGAILYATYHVFLACEEWLEWYSDPVMNPSAFSRLLNRGKDNTDYEWEMFSYIYAARLWLWYAVYAIMSRTVRIAFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC84</accession>
    <name>A0A1D2NC84_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_03830</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC84"/>
    <dbReference type="STRING" id="48709.A0A1D2NC84"/>
    <dbReference type="OMA" id="AFFKCNV"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000001">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="488"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN02850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="847" mass="94523" checksum="11C68DF701B76DF7" modified="2016-11-30" version="1">MADNRSSVSSSPSVSGRSLRSSARGSQQGSVSNGSNVGSAVESTVSSRPAVNGTPRTPRRGAGNESNVGSTVSSRSGVNGTPRTPRHGAGNERSVGSTVSSRPGINGTPRTPRQRPRGEMGSQFNLQSPLNYGTPSSLSTPRTSRLGLGPGTPQRARSDISNDRVVREITVPSQDEGPNLVIWGTNVSASQFKIKFEEFITTYKEPNAEEDEAMGDYEADQPFYMMKLDEIEMLLEPFLNLNCSHLQHFDGDIYLQLVHYPQEVIPIMDQVVNTLFYTKYPNSGLPHQIEVRPFNADKTKSMRYLNPEDIDQLITISGMVIRTSNIMPEMKSGFFKCTVCEYGANAEIDRGKILEPVLCPNCNTNHSFTLVHNRSAFTDKQIIRLQEDLEDTPVGETPYMAALIAHQELVNLVQPGDRIKVTGIFRAAPLRVNPRMRTVRAVYKTHVDVIHYRKVDNKRLREERDGKGYCLTPERIEYIQKLSKKEDIYERLARAIAPSIYEHEDVKKGILLQLFGGTKKEFANTGRGRFRAEVNILLCGDPGTSKSQLLKYIYDLVPRSQYTSGRGSSAVGLTAYITKDPETRQLVLQTGALVLADNGVCCIDEFDKMNESTRSILHEVMEQQTLSIAKAGIICQLNARTSVLAAANPVESQWNSRKTIVENVNLPHTLLSRFDLIFLLVDPQNDAYDRRLARHMISLYFRAPDVSETDDLEMNVLRDYITYAKEMVNPKLTDEASQRLIQVYVDMRKAGAGRGQITAYPRQLESLIRLSEAHAKVRLSETVEVADVEEAWRLHREAVKQAATDPHTGKIDVSILTTGKSSTSRKRQAELAVRSGVYSTQRDEYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC87</accession>
    <name>A0A1D2NC87_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAS-associated factor 2-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03962</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000098">
        <property type="protein sequence ID" value="ODN02705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC87"/>
    <dbReference type="STRING" id="48709.A0A1D2NC87"/>
    <dbReference type="OMA" id="ILIRHQW"/>
    <dbReference type="OrthoDB" id="1026733at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14353">
        <property type="entry name" value="UBA_FAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16120">
        <property type="entry name" value="UBX_UBXN3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049483">
        <property type="entry name" value="FAF1_2-like_UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21021">
        <property type="entry name" value="FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="380"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="467" mass="53961" checksum="87804B6707FF9CE5" modified="2016-11-30" version="1">MDGDAANHLNEAGMEVLLEFQAVTGMEDIDESRQILDRHNWDLLSAINSHMGFDVGSQQPFPPHMDSNHVPPPPPPHNNPQSPSTSRDVNRASTSSNNSNRVGLRSNNGGGGGIISWVWQLFTRPVEFFFRYVWEFIGFGLRFLRADPRMAITNPVQDVVDFIANYETKYGPEHPVFYQGTYSQALNDAKKELKFLLVYLHCDDHFDTEAFCRRVMPYPGFRDFVRENMLFWGCGISTPEGYRTSQALKENTYPFLALIVLKNHRMTVVTRIEGDTEPDSVLSRLHQGVADNEAFLIAERQDRLERSMTQTLRQQQDVAYEESLRADQEKERRKAEEKEKKRQEEMEKQRLEDEERNRREEIKRQKVLAGETLKAEPAANDPDLVRVVIKLPSGTRLERKFLKTDSLKHLYQFVFSHKEAPDFFEIATNFPKRNLPCKITEENPEPPTFLDAGLGRNEMLFVYDLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCA3</accession>
    <name>A0A1D2NCA3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Sodium-coupled neutral amino acid transporter 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_03824</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the amino acid/polyamine transporter 2 family. SLC38A9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCA3"/>
    <dbReference type="STRING" id="48709.A0A1D2NCA3"/>
    <dbReference type="OMA" id="HWFTPTE"/>
    <dbReference type="OrthoDB" id="294730at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF244">
        <property type="entry name" value="NEUTRAL AMINO ACID TRANSPORTER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0458">Lysosome</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="502"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="16">
        <location>
            <begin position="101"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN02861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="524" mass="59582" checksum="41E4DBF8C5FF7E07" modified="2016-11-30" version="1">MSESDFLVVPKAAERRPYHYTRGPGPGTNDNSLQVNVTTSNNEIDQWSERANYSRYLYYSRLRREMNPTDDILLIPPHCIPNDFFYPNFITSVDGKQGSIITIFALWNTMMGTSLLSMPWAMENAGAVPAVVLLTAVAGISFYTAYRILEVYESNASSSLTDLAVLCKRLLGRWAQWLAVIFSALILLGASIVYWILLSNFLFHTVDYIHSVIVHDNTTFAGNSTDLYCPDDSPTTDNETDFGGDTFHRYWALHRTVPLFLVLLLGPIACIRSPTFFTKFNSLGTLSVLYLAVFVFSKWHKYGINVTFTDTTSPIYIPLWKDSFPALAGMLSMAFFIHNCLVTIMKNNRVKRNNRRDLGIAFIFVAVTYFVIGGVFYLIFPLDKNCIQDNFLNNFHSFDIWAFTARIFLFFQILSVFPLIVYILRVQVIYAVTKKEPTMFQTVVSNTVIIGICVGFAIGLPHIGSIIRFSGAFCGLVYLFFLPICLYLKWQQNMNTLTNSSMFWHILLLLVGLSNFVLQFTFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND85</accession>
    <name>A0A1D2ND85_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000083">
        <property type="protein sequence ID" value="ODN03202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND85"/>
    <dbReference type="OMA" id="KCILRCA"/>
    <dbReference type="OrthoDB" id="8250520at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006170">
        <property type="entry name" value="PBP/GOBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01395">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905389" evidence="1">
        <location>
            <begin position="25"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="154" mass="17488" checksum="8F8DEBB34101EDB2" modified="2016-11-30" version="1">MRTLTAVVVISIVLLEIHHLLVMGEVKEKSCRATVQDITKLQLQLLAVCSKELKFKNGKEKSKKTNISSKCILRCAMIKAELTGKDGQITAESVDYLLHKFMPPSLIDKANKTFYPCMEIGLKEKFKTVEEDEFCLTYDPFIKCFMQNAQTFCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE29</accession>
    <name>A0A1D2NE29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000082">
        <property type="protein sequence ID" value="ODN03226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE29"/>
    <dbReference type="STRING" id="48709.A0A1D2NE29"/>
    <dbReference type="OMA" id="EETICTC"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36812:SF9">
        <property type="entry name" value="MYB-LIKE PROTEIN X ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36812">
        <property type="entry name" value="NEUROFILAMENT TRIPLET M PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="771"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="823" mass="93461" checksum="B8646757B364DEE6" modified="2016-11-30" version="1">MEENVKGLIRTCCIVLIISVGLSVVYSAKRPYIYLIEKNYEYNYDRPNLQPQPQPRRTGGNNYNNKNHHPFFRDTHRNGEVTVTSIEAPPSSLAFLTQNEESTSKKRQQSVRRGGAPAQKAVKSNKNEGQLVVTQSNEEKFPFPLPWDWTLRMAEMKREKRIEESNSRKFMLPKLKRVLPTLPPFPTIDFQLETDRGRESRSHTPKRRQPSTAKQIKFAEIITPETLSFISKIQSLNLTNIGNAGGPNIITLGGSSGSSSVGSDEGGSYNPSVGAPLLSGDFFNNMQSRKPLIIPKDTGRQPSSEDIEEYHKNKNKFNKPTTASNKGKESEEDEDQEQEREQEEEDDEAEDDTSVEGADTSQQQSEEEVGSTSKESKEEEHEEKEQDDREHEEKEQEDREQDDKEQEDREQEEQQQDHQSDEEPEPEADKEPESAEVSDEEVQQDAPIPRTKKKTKRPTTYHRTRPSYSPSLSSLAHAHAASQKNASKYQDDQISSALVSDTSSSDAAKPVIILLNVPKPTELKGDTGYEDSDYPFDEMKQKKMKKKKGWGKMKKMKKKKKKKKKKKKKKKGWWPAPTKPPRSKADIINRLTKVHSNVQEVYNVFKGLISDYVVNRPHVGIEFVHTRRQQPPPHKRPPPKKKSEDDDDDDEEEKGHDDKSGEKEEDEKSREMDGDEKSQEKSGDRKLRLPGGSDSYEEYEDGFVAMGGKPTVWNPTEWSFNYPSQASSGGVDTISKRFQECQNTGGTDCASYTIDRPVKYNPPEPLYMETVVSSESAEKPSNPFGQPPPRVSTGSSEKVWVKTWDKEKQGLPLPIDSSELPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEU7</accession>
    <name>A0A1D2NEU7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemolymph clottable protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000064">
        <property type="protein sequence ID" value="ODN03790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEU7"/>
    <dbReference type="STRING" id="48709.A0A1D2NEU7"/>
    <dbReference type="OrthoDB" id="5956066at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.230.10">
        <property type="entry name" value="Lipovitellin, beta-sheet shell regions, chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015819">
        <property type="entry name" value="Lipid_transp_b-sht_shell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015816">
        <property type="entry name" value="Vitellinogen_b-sht_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050733">
        <property type="entry name" value="Vitellogenin/Apolipophorin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001747">
        <property type="entry name" value="Vitellogenin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345:SF33">
        <property type="entry name" value="CROSSVEINLESS D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345">
        <property type="entry name" value="VITELLOGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01347">
        <property type="entry name" value="Vitellogenin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56968">
        <property type="entry name" value="Lipovitellin-phosvitin complex, beta-sheet shell regions"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Vitellogenin" evidence="2">
        <location>
            <begin position="22"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18546" checksum="25298F11CD00E5C6" modified="2016-11-30" version="1" fragment="single">CITLPHLISVGLHVSFGSRQLFTVGDEYKYNYEVLITTGTEEPVSHAASYRLKGVLRVQGTAQNRVTVKLEDVGIGLFNGQWSYFPVPSVNYLPLEELNSLSEPFQIVSENGKFKTLLMNDQEPEWASNMKRGLATYLQMNLERVSPQKLMFFKDEEVRQKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEW8</accession>
    <name>A0A1D2NEW8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metalloendopeptidase</fullName>
            <ecNumber evidence="7">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6 7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000063">
        <property type="protein sequence ID" value="ODN03794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEW8"/>
    <dbReference type="STRING" id="48709.A0A1D2NEW8"/>
    <dbReference type="OMA" id="SPKEFMD"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="8">
        <location>
            <begin position="37"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="27573" checksum="A803694E488647C5" modified="2016-11-30" version="1">MFSPLVYSRIEPTKPKSFEGDISMSRREMKSMQTEILFTGKIHPVHTWREGLVPYLLSSKFTPTEKETIMEAIRDISGDTCIQFIPRSKETDYIDFVKGENKCSSKVGKIGNRQEILMSPQCMRHGTVVHELLHALGLYHEQSRPDRDNYITILWDNLKNPNSKINFEKYGTKFWNEHKLPYDYSSIMHYSSEAFSKKWGEKTIVPKTANAPMGQRASMSPFDKLKINMMYNCRLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF19</accession>
    <name>A0A1D2NF19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Junctophilin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_02821</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the junctophilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000061">
        <property type="protein sequence ID" value="ODN03851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF19"/>
    <dbReference type="STRING" id="48709.A0A1D2NF19"/>
    <dbReference type="OMA" id="IDCENAV"/>
    <dbReference type="OrthoDB" id="284854at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030314">
        <property type="term" value="C:junctional membrane complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000001">
        <property type="entry name" value="Junctophilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000003">
        <property type="entry name" value="Junctophilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017191">
        <property type="entry name" value="Junctophilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23085">
        <property type="entry name" value="GH28348P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23085:SF16">
        <property type="entry name" value="GH28348P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="832"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="90"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="374"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="601"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="742"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="178"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="492"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="561"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="629"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN03851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="852" mass="93664" checksum="2592329E1BDDA572" modified="2016-11-30" version="1">MYEGQWQNGKRHGLGTEYRGRWTYRGEWTQGFKGRYGVRQATASNAKYEGTWANGLQDGYGSETYADGGTYQGQWLRGLRHGYGVRTSAPFGMASHFRPKAPTGSMTSLKSENAEPTSERDRRMDDVRGGFVLKAKSDEPPARRRSLSERSSNFKDSLLKGLKLRKQRSTGDLDKRGTNSSIRSTGSTTSWMSSDSAQSAVTSGSHHTDSNASFVVEDEQMDANVTETYMGEWKNDKRSGFGISERSDGLKYEGEWYNNKKYGYGVTTFRDGSTEEGKYKNNVLITSQKKKHLFLIRSAKFRERIDAAVNAAQRASKIALQKADIAISRTATARGKAEQADIAAAHAREDSEIARVIAKELAPDFLQPGKCIWAEGIRPRPPPPSLPPDLSKFTTQTPMSTSQMSARPGLNTGGREPVEPPRLEEPSSYTNVSSLSSYAPLRPQLPDRLDRTISTPLDTPQFTVTAAQQAPYMNRVNEPSGLYGPPPPPRLGPQHQQQQQQQPHPMDISGGESSKLGMNQSSSIRNSFAPMDSAPHSGPMDTGAMSAVGMGQDRGRDPFRRSQMNPAQAQQQQQQQRQMNPASNNNSNSAYAFQQAMSDHFDHYKRPPSRGSSMDRYGRDRSRGRTPEAGQQNPHSRAQSRQRTPQLLDNPMGARGASNPALDAFLQMETTQPAPRRGETPSRFGVAPDFGVNESVSVSGGGATSLEDATLRHRAGFAQDIPTVPYSTPKRTESLFLKPQAAVPKPTPMPKQISGGGGGGGAALPQRKKSLPDAVSLPRAIPGIPREELAALGSARRQELHRMQEEADRYKANPLLYLLNPNVTNWLSRQKVMVLVVLINLSLAILFLQLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFN6</accession>
    <name>A0A1D2NFN6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chondroadherin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02616</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFN6"/>
    <dbReference type="STRING" id="48709.A0A1D2NFN6"/>
    <dbReference type="OMA" id="VNEHREY"/>
    <dbReference type="OrthoDB" id="8400687at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000770">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001360">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050328">
        <property type="entry name" value="Dev_Immune_Receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373:SF370">
        <property type="entry name" value="FISH-LIPS, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373">
        <property type="entry name" value="SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="388" mass="44182" checksum="79540E2376089205" modified="2016-11-30" version="1">MKNYGDILKRPGVTCVVDSHAISGLDIRHLIVSNTDLAVIEESSLSALETKLELLDLPQNRIQAVPTPALKHLHATRLLTLNHNDITHIGPKAFEGMKSLARLNLYDNRINRIDALAFSGLDTLEFLNLGHNHLQAVPIDAIKRLTNLTSLELQENKITSISERDFAGLKNLDTLKLAHNFITELGPYVFKHLSKASQLDLEGNRINRLDNNAFKGLEDSLKWLKMANNSIREIPTVALKDMHKLQEFDFKKNNISEIKDDAFDMFGKTVKFVYLQGNQISSLPVTVFGEMHSLDHIFLGNNKLEHLMRDVFQPIIDTVQIIDVQGNPLVCDCDLLWYKQWLSQKVGIHDSVKEISLKTHCWTKKPKHEYSISKNDDHTLHHHHLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ68</accession>
    <name>A0A1D2NJ68_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_01368</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ68"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ68"/>
    <dbReference type="OMA" id="NKKDNFW"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.40:FF:000002">
        <property type="entry name" value="alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="13">
        <location>
            <begin position="5"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="777"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="575"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="694"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN05318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="931" mass="102450" checksum="D3F2A1ED0598F7A5" modified="2016-11-30" version="1">MDSSLTTAAIRSSFIDFFKSKQHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGSVDPNSDMAKWVRVANTQKCIRAGEGNLRMVLGVAYTVMKIPGDRLYVTYFGGDEKAGLEPDLECKEFWLKLGVQEEHILPGNMKDNFWEMGDTGPCGPCSEIHFDRIGGRNAADLVNMDDPDVLEVWNLVFIQFNRESDGSLKSLPRKHIDCGMGLERVVSVIQQKRSNYDTDLFVPIFEAIQKATGARTYTGKVGAEDTDGIDMAYRVVADHVRTLTIALSDGGRPDNTGRGYVLRRILRRGIRYAIEKLGGKPGTFANLVDVVVQILGDTFPEVRKDPHSIMDVINEEEAQFLKTLNRGRSLLERTVSKLSPTEKTLPGDVAWRLYDTYGFPVDLTQLMCEERSLSIDMNAYEEAKKRAQLISQAKGAGEDDTLALDVHAINELQSKGVPPTDDLLKYNYSAIDASSYEFPTLNAKVVAIRYQKQFVDQVSSGQQAALILDKTNFYAEQGGQIFDEGFMTSLSKEDTEFLVKNSQVRGGYVLHIGNVEGTISVGDEMKLQVDGARRKQIMNNHTGTHILNFALRSVLKEEPDQKGSLVAPDRMRFDFTNKNAMTVQQVKDAERIAQDMVNSDVEVYAKESALGQAKTIKGLRAVFNEAYPDPVRVVSIGVPVEELQNDPTSPKGLNTSVEFCGGTHLLRSGHIGDFVISSEEAIAKGIRRIVALTGPEASKALKKAALLEQAVTNLKNSASTTPPKEIQRKITELGDEISASQIPYWRKDDLRNSIKELKKSLDDLDKANKAQQMTQIVEDVKQLLTENKFENGYIVKLLNAQSNTKALDAALKQVKALSPNTSAIFFSVDEAAGKVFCLSNCSGEAVGKGLKANEWVGQVAKILDGKGGGKPESAQATGKNVSGLNEALKVAEEFAKLKMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJA8</accession>
    <name>A0A1D2NJA8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sorting and assembly machinery component 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01319</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000024">
        <property type="protein sequence ID" value="ODN05358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJA8"/>
    <dbReference type="STRING" id="48709.A0A1D2NJA8"/>
    <dbReference type="OMA" id="HYDDEFE"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033108">
        <property type="term" value="P:mitochondrial respiratory chain complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="6">
        <location>
            <begin position="151"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="468" mass="52223" checksum="017882D8C094BF06" modified="2016-11-30" version="1" fragment="single">CLVGVERKPDVFANFGDRYFLTMETIIPVEATLDLEGVPVRVKNINFDGLGRTKGDFVAEAVKEIFLAKNFGDLLQKVGNAQDKLSRLETFREVSAVVDVHNISEIEDYKIGDDYDVTFIVKEFSRLAASAKTQMGAQADAQVKTGIRMPNVFGRGEKLEVEYSYSSGSEKNSEISFLKPFPQYLDSSFKTSVFQTRSPNVHAKYMNKAIGSIMSFSCSTFLQLLTLHHKVEWEATWREIVPENTLTPYSIRLECGHAIKSALRHTVTLDSRDRQVFPSKGTYINFLQELAGIGGDAKYHKLDFDLQYNYPLPLNMVFQTSFRVGKLTPFGTSEKSCGIADRFFMGGPYSLRGFCMRGLKIGQDGLSLGGLEHWSAAAHLYTPLPSVNRKFPIIDSCRLHFFVNAGNLADKFLAGNIFKDIRIAYGAGLAVGMGDFARLELNYCLPIRQLVGDKPVKGFQVGVGIHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKR0</accession>
    <name>A0A1D2NKR0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing family member C2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_00810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000014">
        <property type="protein sequence ID" value="ODN05863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKR0"/>
    <dbReference type="STRING" id="48709.A0A1D2NKR0"/>
    <dbReference type="OrthoDB" id="6360546at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010975">
        <property type="term" value="P:regulation of neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.170:FF:000004">
        <property type="entry name" value="EF-hand domain containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040193">
        <property type="entry name" value="EFHC1/EFHC2/EFHB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086">
        <property type="entry name" value="EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086:SF11">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06565">
        <property type="entry name" value="DM10_dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="146"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="299"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="501"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN05863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="949" mass="109730" checksum="41F62AA14FD58656" modified="2016-11-30" version="1">MDASRSNPDFNDGSCTEIPAANYSSTGFIPTTASTPTTKGFLDRYNATSDDTLPYVLPQTASTRKFNTSSAENPFSCRFVIPPGLEDCPALDFDDICDTCCAPEKPICSQDPKCHMFKECRKNDYGNTCKYLPRRGPRIPSWLAHCGRVLTFDGYFQEPVPESDKETYRIRKVLIRYYMDDGTVDVFEPKTFDPGFTQGRLIRRHRIPLPPPADSEFYTMEHFNVGCEVEFYSKTFLICGCNDPTRKYLQKLGISVPHNLEVPDDPYTLWRKDRITSLFARKARIDLTQGKFKNFLLNNRKVLRFWAFWDDRCQEYGHLRKFIIHYFLEDDTVEIKEIPHVTRTEVFPTFLSRGKLFKDYKELVTIPGNKEEALLVLNTTGGCQTVFMDQTFLEDRLCPGINGKAQIKDNDLAIGAVLNVYGRAFIITDCDAFTKTYYQEKYGIQDFTPLTLTEEETLKKLPRMETPPHIGIGDEVDTLANWDKIDIHPPRRDELSLLVMEKDILGFDTRFHKTQHKVNGDRRFIINYFMADNTIKIFEKPHPNTGLKQGTFLQRCRPRKSDTGLMPRYELGEVTEYYQPVDFYVGNILHLNGFQFLLTAADPLTHEYMERNKHLFPQSNLCLILEKVREAIGPLVSGDVLACFSEKDSKCNGVNNVDDFRDRLIQVTKCSLNEHEMITVFRAFKIQADDPGPDMKTLQSVIQTELSRKGFDRYYMQRVEYTLRYHDPCRTGKVDRHTMRSALLAARLPVEKELINFLVEKFEPADDCDRVNYCKVMEFLDYVKNPTPKANPTNIRCIMKWLEPKPPSKIFCVNYREFLETVCPNYRCSLPEKCCPPQPCCEEKPCCEEFVCNPCCTEPDERCLAGRVITDNNPWSERDRCDTQDHCEFQMAYDPYSSNELKRPVCSRMDPRIEAAYECPPPNDCDPPEGGGRELLHCGDYIGFEDFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKZ5</accession>
    <name>A0A1D2NKZ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Early endosome antigen 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01056</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000019">
        <property type="protein sequence ID" value="ODN05636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKZ5"/>
    <dbReference type="STRING" id="48709.A0A1D2NKZ5"/>
    <dbReference type="OMA" id="HYEQYHS"/>
    <dbReference type="OrthoDB" id="8251707at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15730">
        <property type="entry name" value="FYVE_EEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.390">
        <property type="entry name" value="L1 transposable element, trimerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164:SF30">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69979">
        <property type="entry name" value="Eea1 homodimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="8">
        <location>
            <begin position="742"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="130"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="230"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="436"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="513"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="654"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN05636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="802" mass="90793" checksum="6B2D18ADD10D70B3" modified="2016-11-30" version="1">MFNIKNFVNRITDPRNERDGTETAASFVETEEQHSAEGFLCPPCMKAFPSAEALEEHYNKTHAFDDGATGDSNSQPSNAEVQLLRQEIQSLQETLAVSFIFSYFYATLSVAFKLKLNKPFLYCQDERAVSDELKKEMLKMQADLDATELDSKSFKSHEKEFEDSKTLLTSEVTLLRQQLADSLEQISLLRKEKEAISRNSDVSSSDNEALKLEIVSLQAQLSHRNSIDDAEVLRQELVSVQRMMNELALEKEREIETLTNRLNELQSTAPDCNLEERLNQALNELQVIKNSQTAQEKEREQLANQHEAEILNKSNKITQLQQQSQSNENKVEMLQQECNELQSECNRLREQHAELCSKIETGEGAKAALEGLQKENEVLKQNSDAAQSQNRELSKQQHALNVQLEKSMSEHKLAQDSLDAKAKELKALKDSTDSLIATKTEELAKLQKQNGELSTSVQAKESEVSKLRKELQGVQDQFGTLKAEKTKLLETEKTNQKTISEQQVSIQSLTKQHTESLKQIEVLQSSVANLEKNVASKNEEISKTNKDLDFTQSVVKELQDSLLSSQAESNETKEHLEKQVAGLEHQLNEQSAALQEKCKESDQFKQAMEEELTNVRNKNDTLEADLLQKATEVENLNSSIIEVTEESVQKNQTIKLLQSKIDDLIQNKLELEQTCASNEEEKSQLLEKLISYENECKTYTTVIEETTRKRDDAMAALQELGRENQSLQIEIAKIQGRKWADDSNVSNCSTCTKEFTLIIRKHHCRHCGQIFCNDCSSKSASVPSSKKPVRVCDGCFVKLTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLB8</accession>
    <name>A0A1D2NLB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tenascin-X</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLB8"/>
    <dbReference type="OMA" id="ECAIDEN"/>
    <dbReference type="OrthoDB" id="409374at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069">
        <property type="entry name" value="ECDYSONE-INDUCIBLE GENE E1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069:SF8">
        <property type="entry name" value="FI17111P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905714" evidence="1">
        <location>
            <begin position="22"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="379" mass="42238" checksum="E6679028C86A833A" modified="2016-11-30" version="1">MNKFKLLCCVLWVLTLNLASAYMDPYLQKGYKESCSNDSDPCNSVKFLSCLEGQCLCSSPGELVYDYGRDQCVALASYSCLRVMPDSNSVQDPKYQIGCTDYAKCAFPGDSCQCDFTYYEAENHTCIRQHDYGAECAIDENCDQFRFFSCINGKCSCDPNKNHRYDQKNDKCMVPVGEKCRVIEFQSINEKQFKTDECAQHASCEGGTCRCNAGYRISSDRTCEPLFSLVSGPCTTDREARNTVDPHFIQNCTENAYCQESQAFSYCKCKEGYVETNDGLCVKAYGQSCEMDEECDNLAPLACIENSCGCADHLQVFDDKLRRCVGLAGSRCWKDSNTTAAVCTTNAYCVKANAHLNYGKCICARGFVTTSQKTCSKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLI9</accession>
    <name>A0A1D2NLI9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00559</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLI9"/>
    <dbReference type="STRING" id="48709.A0A1D2NLI9"/>
    <dbReference type="OMA" id="RIMHIFI"/>
    <dbReference type="OrthoDB" id="253091at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033549">
        <property type="term" value="F:MAP kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020405">
        <property type="entry name" value="Atypical_DUSP_subfamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45682">
        <property type="entry name" value="AGAP008228-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45682:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01908">
        <property type="entry name" value="ADSPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="26"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="9">
        <location>
            <begin position="104"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="7">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR620405-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN06111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="186" mass="21340" checksum="973364A5FDA13DB9" modified="2016-11-30" version="1">MSKEEIRLQLQNVLEIESVPYWNHLDQVYSEPAIFIGDEYAAKDIDTLRQLGITHVLNAAYVPSRTHYHSYGIVNTDHDWYAVRNFNCEFLGVESLDYPQFDLSRFFEDAADFIDSACCSKGKVLVHCYVGMSRSATLVIAYLMIKKHMLAIDALAHIREKRAVYPNSGFVDQIIDLELRLRSLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMA0</accession>
    <name>A0A1D2NMA0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dopamine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMA0"/>
    <dbReference type="STRING" id="48709.A0A1D2NMA0"/>
    <dbReference type="OMA" id="MAICKVT"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="GCN5-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20905:SF1">
        <property type="entry name" value="AT07410P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20905">
        <property type="entry name" value="N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="GCN5-related N-acetyltransferase Rv2170-like" evidence="2">
        <location>
            <begin position="178"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="273" mass="32144" checksum="4C86E35520FAC488" modified="2016-11-30" version="1">MLGRNYNKLNLFQNNTSNPLFSLNYSVTVICLCIRLWLWWVHSKLGITMETPSESTWKEFTFKFIELSDYQSVLTHLKNNFYIEEPVNKACGFTPEREHDYNTRMTDMLNRYQKHLAVVPTNEPNWIIAVLITNFHDLKNPLPSFEPRSPITTKFLHVLEQMESTFNIHETYGISNFPELAILSVEKEFRGKGLATELFRRTISQLFSEGFPLIYSEFSNPISRKVGKRLGFEEVRRFYFKDFTMPDGSQVFKNEEEQDNFVNMTVLTKPKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMU0</accession>
    <name>A0A1D2NMU0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Cell differentiation protein RQCD1 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_00088</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMU0"/>
    <dbReference type="STRING" id="48709.A0A1D2NMU0"/>
    <dbReference type="OMA" id="EKVYTWI"/>
    <dbReference type="OrthoDB" id="1183224at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000037">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007216">
        <property type="entry name" value="CNOT9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12262">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04078">
        <property type="entry name" value="Rcd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN06590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37556" checksum="99279E96E34918CE" modified="2016-11-30" version="1">MDMPQNPGDQFQQQGQQQQQGNSQQQQNQQGNQQQPYSGPAQIPQAVDRDKIYQWIAELSNPATRENALLELSKKREVVLDLAPLLWFSFGTMASLLQEIVSIYPYINPTTLTAHQSNRVCNALALLQCVASHTETRSMFLQAHIPLFLYPFLHTTSKTRPFEYLRLTSLGVIGALVKNDEVEVITFLLTTEIIPLCLRIMESGNELSKTVATFILQKILLDDSGLNYICQTYDRFSHVAMILGKMVLSLAKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDSTFSKCLKDDKSTKHWLAQLLKNVETSPPTSAQSNGPDLSTPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNV2</accession>
    <name>A0A1D2NNV2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NNV2"/>
    <dbReference type="STRING" id="48709.A0A1D2NNV2"/>
    <dbReference type="OMA" id="KSTEDYG"/>
    <dbReference type="OrthoDB" id="8291435at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.820">
        <property type="entry name" value="PHR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038648">
        <property type="entry name" value="PHR_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN06616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18937" checksum="EFAD3477B684BFC4" modified="2016-11-30" version="1">MALQESGVGRALELTVSRGEKIKEKSTEDYGGVYYTNSLRVDRPIRLTGFTFFAPVTPGYTEYSVIVRKMRGEEVVGRFQVSKSMAELRGVTNQRIRINPPWQIPIEANVWYDVKFKIEGPKTPFLENKERDQVVYSDDPPRRALATFYFFTGSGQLPEYHFVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1E7</accession>
    <name>A0A1D2M1E7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007263">
        <property type="protein sequence ID" value="ODM86786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1E7"/>
    <dbReference type="STRING" id="48709.A0A1D2M1E7"/>
    <dbReference type="OMA" id="ISINIKW"/>
    <dbReference type="OrthoDB" id="6584069at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="2">
        <location>
            <begin position="85"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="453" mass="52479" checksum="FEAE2319CE1C494F" modified="2016-11-30" version="1">MHSWTDQVGYPLVKVEAVNDAFVKLTQKAFKVSDEEEYSNQNATWAVPLTVYTEKRPLPQSITVPQFWWKENGTDLHFEHNISSWFMINHSVSGYYRVLYDDSLLKLIQQQLERNASVINPLSRAQFVDDYLIFTEKNYSNIQTALNLTRYLEQETEYVPWRIVFNHFDQFYQRFSSHFGYPVFQEYLNKKLDSALSSIGIEESPEDKRMRTFLRSDLLRWACTHGEPSPLCAQKPRSFWKLGTSMDNSGLLSQSLSCAAVATGGNDAFDILYQRYETLANNNGTKDEREEVLRPLTCATEKEILEGLYNKTANENSTIFLMNDGKFILNALIEKSQGRVMLLPFLNANLDKVLDLYNTWNKPQRSRGKRTSYIRHEGAELVENLLSKASIFYSTQAQLDEIDAFAKENKIKLLGSYVNIQYVLGTRKHNVEWMNTTGQSILEWLQSVEDDKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2J1</accession>
    <name>A0A1D2M2J1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005933">
        <property type="protein sequence ID" value="ODM87189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2J1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="24892" checksum="D496CB14CEC68EDE" modified="2016-11-30" version="1">MVGARNFITSHFQQRQYSATSEEDRQPRRFRIPPGFATYDRNGIQYPLSPLSTSSSSSSSSGSEDEGFPGNLRTLPSSTFMSTPRRRISSLPPIHHHSSNSAQKESSYTPESSPMHSFENAFQPLHASTFVNRASLSEPDFTDYVSLSKDDYLYLTPPTYHTPGGQFGAYIHFQCFNRRSYGSKPQPICYEPIVIFKNKTITTYLLFKFENIFQHFGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M320</accession>
    <name>A0A1D2M320_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-1,3-glucan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005489">
        <property type="protein sequence ID" value="ODM87360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M320"/>
    <dbReference type="STRING" id="48709.A0A1D2M320"/>
    <dbReference type="OrthoDB" id="6733755at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903433" evidence="1">
        <location>
            <begin position="20"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="87" mass="9599" checksum="91D5EA3FD50519CD" modified="2016-11-30" version="1">MSFTIKLVGVLALLGVALAGNVSVSTSSFGAVYAPGDLMFEDNFDKMDLATWQHEITMSGGGNWEFQVYHNHRRNSYVAGWHPLHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M341</accession>
    <name>A0A1D2M341_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19306</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005456">
        <property type="protein sequence ID" value="ODM87376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M341"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="8550" checksum="E160405E21537A4F" modified="2016-11-30" version="1">MTRRLTTRGNGSERCPVCGALWNLETFGDEDNSKKAYERKVPKLTLTIHSNQNQLLLLDVEELGNHKRILVQEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5U2</accession>
    <name>A0A1D2M5U2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18349</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003755">
        <property type="protein sequence ID" value="ODM88333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5U2"/>
    <dbReference type="STRING" id="48709.A0A1D2M5U2"/>
    <dbReference type="OMA" id="KEIMMKM"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000134">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="544" mass="59434" checksum="6124627CBFE0C497" modified="2016-11-30" version="1">MQPKKAAIGIDLGMTYSCVGVFQNGKVEIIANDQGKRTTASYVAFTDTERLVGDAAKDQVAMNPNNTIFGAKRLIGRKFDDPKIQQDIKTTHWPFTVIDDNGKPKVEVNFKEETKRFSPEEVSSMVLVKMREVAEAYLGHKVTDAVITVPAYFNHSQRQATKDAGAIAGLNVLRIITESTAAALAYGLEKNVGNKEEKTVIIFDLGGGAVNVSILRIKDGIFEVKSTAGDTHLGGEDFDNRMVDYFVQEFKIEHKKDITPNKRAVCRLRTACERAKRNLSSSTQASIEIDSLFDGIDLHRSITRARFEELCADLFRGTLEPVEKALRDAKMDKSQIHEVVLVGGSTRIPKVQKLLQDLFNGKSSEIERVWLIDVAPHSLGIETTGGVMNRIIVRNSTIHAQESQVFTTDSIRVGGEDKPNVKVYEGERAMTKDNNLLGSFDLSGIRPAPSGVPRIEVTFDIDADGILNVSAADKLTGKTSCSRGFKWLDNNPLAEKEEYEDRLKEIMMKMNGAGSAAPGGAGFPGGFPGGAAQPSAGPIVVELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M621</accession>
    <name>A0A1D2M621_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003714">
        <property type="protein sequence ID" value="ODM88354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M621"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903517" evidence="1">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="7234" checksum="62A71CCFA49A0E4B" modified="2016-11-30" version="1">MKVFSLAVVLFGIISIAFGSPTAKADSGGDEDAEGRGLIGGIVGTAAGTAVGAINTVEGMLPGMGGGGGAGGLLSGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6G0</accession>
    <name>A0A1D2M6G0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003423">
        <property type="protein sequence ID" value="ODM88567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6G0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="8910" checksum="53DCF0A7BDDD32BC" modified="2016-11-30" version="1">MSSASFNSERNFLYEYDCADQISKESRLVKGLKSAWKVMFQYLEETLPIPTHFSDSIVDASVPTIRRNDDDFTQPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7E0</accession>
    <name>A0A1D2M7E0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Macrophage colony-stimulating factor 1 receptor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17795</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003089">
        <property type="protein sequence ID" value="ODM88886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7E0"/>
    <dbReference type="STRING" id="48709.A0A1D2M7E0"/>
    <dbReference type="OrthoDB" id="8196102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF600">
        <property type="entry name" value="PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM88886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="188" mass="21222" checksum="AF60C6470C7DE141" modified="2016-11-30" version="1">MKNLLGSGAFGAVYEGRVKYEDNSNEIRVAVKTIMHSSPPTARAGLLSEIKVLSYLGKHDHIVNVVGAYTKAIKKGKLYLFLELCELGSLDKYLRGNMSSPCKENDADTKEEQHAVENYYKGLKAESGNGDDENFEDVVVAEYSGNRQTENQKMTFFQEDLYRWSREILNGMEFLASKNVMSILYKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7F4</accession>
    <name>A0A1D2M7F4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CUGBP Elav-like family member 1-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17776</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003070">
        <property type="protein sequence ID" value="ODM88906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7F4"/>
    <dbReference type="STRING" id="48709.A0A1D2M7F4"/>
    <dbReference type="OrthoDB" id="267048at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="19"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM88906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11908" checksum="365884386A2E902A" modified="2016-11-30" version="1" fragment="single">VINGDTFGAAGELPDPDSIKMFVGQVPKHMNETELRDLFEQFGRVYQINVLRDKVTKQSKGKIHLSYAYIINCSCIPLPFHFTLLVFWGEKDEMRREWLELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7G7</accession>
    <name>A0A1D2M7G7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003108">
        <property type="protein sequence ID" value="ODM88862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7G7"/>
    <dbReference type="OrthoDB" id="6412905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="33280" checksum="B67E6C55F854E654" modified="2016-11-30" version="1">MVAFVSDTCATVDLLVGGEFFEEFLGACQEPVKVKVGLEIELEDKSLFSINSKEMSPCVSIRKTPGTNPKTLAFEDKLKVEVKKPIRTDLAYRGTVTIEMLVIRKVVISDLPCGTGILGQRILENKVESDFSIIADDGTRLECNKRALAAMLQMDCKESREKVIKLNMSAKGVEALLKFIYYSNLDDPMKTSNIAFELLEIGHQYEILGLENAMRNILLGQKCEWFEIDAVVLLYLWTLKVDGNEDLKWKALLAFKLKPDELKSSRVFDKLLKEDPNSAKDLFAICLKTLSCYWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M853</accession>
    <name>A0A1D2M853_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fibronectin type-III domain-containing protein 3A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002841">
        <property type="protein sequence ID" value="ODM89167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M853"/>
    <dbReference type="STRING" id="48709.A0A1D2M853"/>
    <dbReference type="OMA" id="GETEAMC"/>
    <dbReference type="OrthoDB" id="443915at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF11">
        <property type="entry name" value="FIBRONECTIN TYPE III DOMAIN-CONTAINING 3BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00014">
        <property type="entry name" value="FNTYPEIII"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1091"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="160"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="269"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="366"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="458"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="550"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="649"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="766"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="853"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM89167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1115" mass="122398" checksum="E9B1C189652E221D" modified="2016-11-30" version="1" fragment="single">GPGNNGQPFYPPGPGYPNAQFTPMQAGGVPSGVPSSHPNMPTAAQNAGMGPNSYMGSLPAHAQRDERVQRQYVKLRRKLDQKQQSNSYNNPYSQNGPVRKDVNYVNTNRRNISNGTSKPTTNGGAEEDGSVGSTGSVTSTGTQDEEEENRMLAQTEMLSALIPPTVSDVTSRSAFVEWNHPDRFTEAGENKYPDVDVSDSDFRYEVFISDRSRDNRFKSIFTGSALSCRVKDLKPGTMYAIQYCAMVGDVKGQPSTPANFNTLPAEPDPPLSPKVVSRSRSSIQLKWTQPVNDNGSKIINYVLEYDEGKGGNHFVEYYRGKYKQVTVSKLQPAYSYQFRVAAVNTVGQSRYTQVIPAMTAGSPPTQPAPPFLAEAGVKYLRLEWVSRATDDEYTLQMEDPSTGHGFLSVYSGSAPQSICIDLKRNTKYKFRLKAQNEEGHSKWSEEVILSTLPDRPGPPHKPALKGRVHAYGFKVKWDPPTDTGGLPITDFALQIDKGNGFEEIFRGSETEFNIDRLSPGQSYALRVIASGPGGESDPSEPCVITTEPVCPGKCHIPRIVGKPKSNSVHLKWNPPDWDGGSPINQYEVGCTTPDNQTQEAYRGKETDCFVNRLLPGRVYLFCVRAYNRIGAGPWSDPLEVVSGAGSPDAPATPKVTTKTAHVALVSWNEPLNNGSAVTEYRVQLATPSTSISGSGEDNRDEGEIKSVESDAQSISSFNVVYTGPSTSCEVKGLHPASIHLFRVQAINSAGFSEWSPVASHQMPPSSPNAVGSVEALSTSNSVTLNWKAPSCNGSSIIHYNVIVGETIHVVSAESFVLDNLMPDSHFKIRIQAVNNVGPGALSSSVKVATKPLPPAAPKLECVSVAHFWMKLKWNDAASKNVEYLVQMINPYKDEFEVVYRGTSTSTKVTRLTEDTEYQFRICAINGAGQGPFSDLYKFSTSKSPPPQVKGVKVEFTKDSNSFRIEWFGVQCNDTLEYQVQICRRRDQDYRTIYRGNERSTEMKPQDLDDGASDYLCRVCAIRICDDRTQLIGPYSVPFTFHAPDSVLNDFASSKIHSSNSSKSLSTTAQVRSTFFQVLEEKMNEISYESRVGILAVFALIILAFVISLITHHVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8N4</accession>
    <name>A0A1D2M8N4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002708">
        <property type="protein sequence ID" value="ODM89346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8N4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="672" mass="73504" checksum="C10AAF66DEBABC78" modified="2016-11-30" version="1">MAEEGPRKAPPGAAPGEDLGRNRPTNQMPFVGPPVPSSLNQVNHSNVQSNNGVVNPQTQGMAPPLAAAGPPVQAPPFANFNPTTGVVGNINLNALNNPMAWSGMKNVRDPDIDAVLNESWNTQLVLVGWSPHRKPVMNLENDVFVRSLTEDPWRHSGNVVFFCDGKKIVRCHGILLQSILPEFYEELLHMANFQYNPSCRSPELPYIPICVTGVDQRCIEHFLSLIFRGIAVMTGKEVQQLLQVLENLRIHELVVCIAPTPGNNGNPEWLNTAGATTTTTAAQPSSPNSIAMSSTASVPPPFISFQQDVKSNNPMDNSEPGNRQPMTVNTQGDVNKLEPAPFQSIGVHSTGLLADETYGFGQASLRPNRKNYTLTNNSGSTSSASGDEQMKTVKTVVIKQSSRPRRTSNRIQKAIVKTESTAPPPPMKTPPKGSSSQSPPILGNVSFGLTPSSSSLPGARSSPVDDESPNPVVKRRRRTRAKSEKVLEKKTPRRVSECRGSPSDGDDEDETDRKKRKRTVYPKEMRGKALDALNEGKQVRDVACELNVPSKLISRWKYEAKKAETEDITVPAVTINDDDPPFEPNATTVSNIVNKNSLSFDFGGENNDNITNPYMKIKSEPMVEYYGGNTADLVAFSESHPEMSMHPMNIFNIDKQQNLSIEDTQNQDETGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8R8</accession>
    <name>A0A1D2M8R8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002747">
        <property type="protein sequence ID" value="ODM89294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8R8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="213" mass="23650" checksum="9EE5CD7E2C604C79" modified="2016-11-30" version="1" fragment="single">MKIMGRKRKAGASRVANPSFLCVISRKDTLEFSPLFLIFGKLKQSTGYLSLYCIKAWESPSNSFKNFKVDFCLMRDPSIEALSGSAPEQSTSSWYSSLPNTEYNPYPLRGVMRVGGIKDVRVILMASTVNLPISLLESHQFGSLARDHLHAIITPLNEVPGAPVVLPEPGSTRSGTSFTSSSHSISTAGQRQLLRLARLRFNFQVKQYKLHIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9F3</accession>
    <name>A0A1D2M9F3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylethanolamine-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002495">
        <property type="protein sequence ID" value="ODM89616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9F3"/>
    <dbReference type="STRING" id="48709.A0A1D2M9F3"/>
    <dbReference type="OMA" id="QEVICYE"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.280.10:FF:000006">
        <property type="entry name" value="protein D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903654" evidence="1">
        <location>
            <begin position="29"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="216" mass="24470" checksum="19335B53F374EAFE" modified="2016-11-30" version="1">MGVTDRNKLILATFFFLAVSLWNNFATATKPQPTGIEEMEKEQIVPEVIDTAPKSVLNVTYGKLEVKLGNSLTPTQVKSPPTITWNADPKKLYLLCMTDPDAPSRQEPKFREWHHWLVGNIPGTEIAKGETLSEYIGSGPPEGTGLHRYIFLIYEQPEKLTFDEKRLTNRSGDGRGKFSIRNFAKKYNLGQPIAGNFYQAEWDDYVPKLYEQLSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9X8</accession>
    <name>A0A1D2M9X8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Death domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002363">
        <property type="protein sequence ID" value="ODM89786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9X8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01670">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Death" evidence="1">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="116" mass="12723" checksum="3B94EA37EBFA932F" modified="2016-11-30" version="1">MAQAQTGIDRMDVGNQLLLGDQDCPYEDIMDAIEGSASPGILYSKWKDFGRRLNTPDDTMTTLELNIGKPGNTYRNAISTILKESNGKPLSDVISALRKCNVNDIADAVTNKFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAL8</accession>
    <name>A0A1D2MAL8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Speckle-type POZ protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002224">
        <property type="protein sequence ID" value="ODM90035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAL8"/>
    <dbReference type="OrthoDB" id="6412905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="204"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="34587" checksum="04C61FB501219C4A" modified="2016-11-30" version="1">MEKFLLKDHPINLKFSVMNHNNGGNYRRGNAASAGAAEFFKPRHGQEYAKTKLPLLNFKRFQNFFQQQRLRWTKVVLKKFSSTFCVQWWIIIGYSRMIPLNKIRIYGSPLDQLLALNKDLKLKFNVVFDQNFVANEMVACYDDYGKCYFENVIRSEHYFVSLSGYNGIFGHVSIELVGLDIPMGSLPDDLRSANKKLLEEQRFTDFALVAENGQKLPCLRAFLATASPVFDRMLQSECKETKEGACKLDISAEGVKANYLILLLDVPSETPSVALELLKSGEKYDIFGLEAAMKTIFLSNQSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAW8</accession>
    <name>A0A1D2MAW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arrestin domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_16546</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002148">
        <property type="protein sequence ID" value="ODM90136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAW8"/>
    <dbReference type="STRING" id="48709.A0A1D2MAW8"/>
    <dbReference type="OMA" id="NIVIHYI"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF176">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="214"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM90136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="410" mass="46460" checksum="ECDBB2A6EEC62D06" modified="2016-11-30" version="1">MGAKIVLYIILDVQRKNIVIHYIMGVTIFINFENNLTAFYPGQTIRGKVTLQNDSDAKTKGLTLIFFGETEVYWTESAARTDTVSPHRQPQQTSLRRHVQREYRNQETFLCHEILLHGHSAQGRKDEEFIISPGIREYPFAFQLPMALPSTFTESAFGFVKYTAEAKLSRSMFRYDRFEKEFFINGILDLNFIPNVFLPIGQDKRVEFGWPCCSDAYMTLDLKLEKSGFVPGEQIRFSGMVLNFSLETIERVWATFTQTVHFMTFDRVKTTTTDLLFTSYGSPVPYRDVIDWNDSFAVPSSLLPSGLAGCTIIHVNYQINLHAKPSGHDFKTVSAKVIIGTGPCSLHPSAIPPVLETQPSTSNTSMENSGIVFNPTTEHEIHQAQSSTKMEYNPSLNPFLESEPEENTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB02</accession>
    <name>A0A1D2MB02_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002135">
        <property type="protein sequence ID" value="ODM90166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB02"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903743" evidence="1">
        <location>
            <begin position="17"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="270" mass="30343" checksum="2DCA11D2FA6917CA" modified="2016-11-30" version="1" fragment="single">MKFLLVFLALVGARSAESVLKCWECQSEHGFHPFECDHINEGRSVDCTSPRAGWNPFALRGSGPRIRETATLTFGSRSFVAGWIEQDWGCHRKTACASRMLVQIQGQLQSGGDSRPRKSGEVVMLPSTNLLALLTFGIIIIQLGKLRFNLLLLLIGLVTTSGFPVGSEALQCKTGYEADSNSIICNGTNPFCYIRMIDAYQPEEPRIYKGCLEEKEFTPERRHQGLNNHCIVDHTRQIDVWCYCNDKDDCNMEAINEVGNRDVVRFAKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBE9</accession>
    <name>A0A1D2MBE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hyaluronan mediated motility receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002034">
        <property type="protein sequence ID" value="ODM90327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBE9"/>
    <dbReference type="OrthoDB" id="419631at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="122" mass="13997" checksum="92F63E7812F3F070" modified="2016-11-30" version="1">MSFSRAPIKRFNEINNGVPSPTKYYVKYPNDIKVCIPPAVKTNYPNLSGRNNPPDINRCKSVPNLKAMDRNRLQRSTSSGSTQDLSLEQTQSSIYCHPRHPNLYLLLRLKRDSVGYISWTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCA3</accession>
    <name>A0A1D2MCA3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein lifeguard 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_16045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001872">
        <property type="protein sequence ID" value="ODM90636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCA3"/>
    <dbReference type="OMA" id="SIRMGKF"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10428">
        <property type="entry name" value="LFG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF47">
        <property type="entry name" value="TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM90636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="35098" checksum="E7B8955C1EBEDDEB" modified="2016-11-30" version="1">MAFNSQQQGYGAFGGNPNPSAPPYGGGYPQQGGYPPPGGFPQQGGYPPPGGFPQQGGYSQQGPPPAGFAGPGAGYPQGGFPPPPPHIGHFIDPEFKSDVNEFTFSDKSIRMAFIRKVYAILMVQLLVTFGFVALFVMNEDVKLWTRANPGIFYGALALNFGCIIALACCEGVRRKAPGNFICLAIFTIAEGFMIGTFSSAFKAESVLLAVGVTAAVCLALTIFSFQTKWDFTAMGGVLFVALIVFMLFGILTIFLPKTTFPTLHIVYACLGALLFSFYLVYDTQLMLGGKHKCSISPEEYIFAALNLYLDIINIFIYILSILGSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCU6</accession>
    <name>A0A1D2MCU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pleckstrin y domain-containing family M member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_15886</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001791">
        <property type="protein sequence ID" value="ODM90800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCU6"/>
    <dbReference type="STRING" id="48709.A0A1D2MCU6"/>
    <dbReference type="OMA" id="TCREPII"/>
    <dbReference type="OrthoDB" id="62364at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17679">
        <property type="entry name" value="RUN_PLEKHM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051366">
        <property type="entry name" value="DEF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025258">
        <property type="entry name" value="RH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047326">
        <property type="entry name" value="RUN_PLEKHM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12326:SF12">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY AND RUN DOMAIN CONTAINING M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12326">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13901">
        <property type="entry name" value="RH_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01175">
        <property type="entry name" value="DUF4206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00593">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RUN" evidence="10">
        <location>
            <begin position="49"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="298"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="452"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="298"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM90800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="814" mass="90736" checksum="8E15B27C5830C30A" modified="2016-11-30" version="1">MASSSALLRKAVDKTEAMDTAVKWSLLERVNDSVKELQLKCTSERSSVLNNDETTNSFLWVLEAVFIHGLTNSFLRSAASSASSPFSSLMKSSFFSSARGSGGAGGSGSDSQAVPNPSIWEFVLVFLHRDIIDQINSLHLIHTDVGRCRSWLRIALNDGLLLSFLENMTLKSNRRCLRSFYRSSAFLRDGEKCDILKNYLMGVELLEFRLVINNSFLNHWNSGPLSLVGLWVDENESVQQGVDVAQNLESKEFQAIPKLHQRQQNGGTPPRFYAELDSVLRRPPPLLSTDDALRIILSSSPRATPQPVQQKTVSQPKRMPLSSSSPKQKLNTVQTSKNVASSSKPSPSRSRSPLKVQAHDNVSVEEAQDPLAEDKRSSPKNQPVITTPTSEPVSKTSKPNETPAVIINGPQELPDAPSTNMDESATFMELELESPMVERSYTDLLLKYQQRSQNQQQQLQQPDAQNEKISEETNEENPSSLIHHDSLGESCDFTGNHSPTTALTASVTSSSGGSGSCKSGTKTRRRRRNTSLHHVKPDIVDGLELIKSPLKTKEHIMELLPRISKYTKIIAPEAGLDSQNYACKMCGTSIGMIYGAARLCHFTGFSYCNVCHLNQESVIPSRILLNYDFGLYAVCNQAHDFLEELKDEPIFDVNEINPTLYDEIDECGQAKHLRTKLYYIGMYLKTCKNSKALEELRKEGSSKPHLLESIHMYSLTDLLAIPNRSLATLLTKLVSTGSAHILSCTICREKGFICEVCRSPQVVFPFELERIFKCCDCGAVYHNKCMSPGQPCPRCVRWKKYQENEKAELSNQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME50</accession>
    <name>A0A1D2ME50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001608">
        <property type="protein sequence ID" value="ODM91280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME50"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903882" evidence="1">
        <location>
            <begin position="18"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18672" checksum="9B537F12C1EEA297" modified="2016-11-30" version="1">MKLTGIILLAFMAAVSGFDYLATVDKCFEGLNKQESLVKNLDYYREGAEYCQRQLKYKEVFCQTTCQFLELDVIECTKNSDICRMITNPPREFIMSLTAVSDHDDTPAPQHIAEKYSAARNSVEPPKTTGDVANIIFENVEERLKSCSVNESTLIIPNVLNFNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEE1</accession>
    <name>A0A1D2MEE1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001575">
        <property type="protein sequence ID" value="ODM91380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEE1"/>
    <dbReference type="OrthoDB" id="8287350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="12007" checksum="D76CE2936D438615" modified="2016-11-30" version="1">MCHKISKHNKHWPTTWICVVVCIIATLFITGCVCDEENSMPSEEMHEEEPEKKKKILDWATAVIGAGGKTLGEFIRDYEVHVLYEFVFIFFQWAFFFYAGLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFD7</accession>
    <name>A0A1D2MFD7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001482">
        <property type="protein sequence ID" value="ODM91604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFD7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="20134" checksum="8599650958FEA645" modified="2016-11-30" version="1">MYYSYLSCYSCLRSITVTEALGASAIIATCATQRETGSAPLLLHGASSRCYQAGSQGPCEPNHIIAQSQISSHLGLQYGICKPVDSTPMKLEELFKLQQVLQRIREESSRQGQESLERLLRKQRTLKQQMQQDEKRLQPLNGEAMMKITHGIHTITCPSGQYYSSVLKKCFQTRRWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHM5</accession>
    <name>A0A1D2MHM5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Chymotrypsin-like elastase family member 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_14187</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001213">
        <property type="protein sequence ID" value="ODM92499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHM5"/>
    <dbReference type="STRING" id="48709.A0A1D2MHM5"/>
    <dbReference type="OMA" id="AHCVQHM"/>
    <dbReference type="OrthoDB" id="546450at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000146">
        <property type="entry name" value="Serine protease 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904041" evidence="11">
        <location>
            <begin position="20"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="12">
        <location>
            <begin position="183"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM92499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="421" mass="45291" checksum="5E5035227E9D55F8" modified="2016-11-30" version="1">MKLGLLALASLLFVGFAVAGTWVEDDTVIIDPYTAQGSSRLKREETAQELRVDEEDTVLIKSSSCVTTKGRTGQCMSLRECFPLLFPIDPTVEMPSGVTLSDPLADQLIASSGFCGGGEYRSDSPSLFAQVVRAEVLVCCAMQSRIPPPLPPPQMNATLQNINPSRASCGNIKIDPKLLPQGLDGNDEKIVNGRPAQRALMSSNKQFCGGSLIDSSTILTAAHCVQHMGADEASKLTIQIGDHHIYSTSDGTHEIRTVSRILYHRGFSMQHLHHDVAVLHLARPVSNTKYIQPVCLHPGTPSYDNVYGDVAGWGQLRDNGPQPSTLQTASVKVWTHDECSQKYSGHAPAGIGEGMLCAGGSGKDSCRGDSGGPLTINSRSQAQEVGIVSFGVGCGSFPGVYTRVSRYVDWINKNRKRSLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHV5</accession>
    <name>A0A1D2MHV5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial GTPase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001218">
        <property type="protein sequence ID" value="ODM92482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHV5"/>
    <dbReference type="STRING" id="48709.A0A1D2MHV5"/>
    <dbReference type="OMA" id="RAENTEY"/>
    <dbReference type="OrthoDB" id="269151at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000004">
        <property type="entry name" value="Mitochondrial GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="58"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="29649" checksum="D8E2B18D003D61C0" modified="2016-11-30" version="1">MQAKLRSVDCVMEIHDARVPLYGRNPNFSHLNPIVPMVRDMIENSNRYHREGMEEYNAMIIGIPNVGKSSFINITRAKNLKKVTSLKVAPSAGVTKMVHMKVKISNYPIIFLYDTPGILTPRVSDPTAALKLAVCGSFPDHDVGLMLIADYILFTLNRQKNYKYTSLLGLEEPCDCITMALTKGAIHLNKMQQQRSMALESGLHKKPNFEYMSKMFIEKFRKAEFGKIVLDDLDQFTQFEQCNDDFELKENEVFEKSGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MII1</accession>
    <name>A0A1D2MII1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Beta-1,3-galactosyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13875</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001142">
        <property type="protein sequence ID" value="ODM92808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MII1"/>
    <dbReference type="STRING" id="48709.A0A1D2MII1"/>
    <dbReference type="OMA" id="CKSTPEN"/>
    <dbReference type="OrthoDB" id="115198at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000001">
        <property type="entry name" value="Hexosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF3">
        <property type="entry name" value="BETA-1,3-GALACTOSYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM92808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="532" mass="60452" checksum="398923BFA74749A0" modified="2016-11-30" version="1" fragment="single">MHSLKVQEKPRSIGRAYAGDLLVQIAQHEDHDDKQYGYMFASSPQESPVYSPSPTLTREDIWPSRTRSRVLDSESPFPPVFFPRNSKRSSKPYSPPGSSPVKVSLGFRIFQITSILIVGICMYALVENILFLVKSYGDDSYQDESKRSSVNIHEQLQSWIIHGEEELSILPQMSSGGNHIISSPVSGSPSEIGHKPKEINHAMVSTHNLTFIHNASSVCSSVRTKSQGRLNSLSSSSGATGEGIYFMIVVHSAPDHFTERQAIRSTWASVKTLKNLAIRTVFVLGKYQLSPSPTLENSIRRENELFGDIVVGDFIDCYRNLTYKHLLGYKWINKYCPGATFILKTDDDAFVDIFQLFDFISRTYGFAPKPGTLICNVFPEGTKPVRAKKARGSKWSVTMDEYPHSVYPRYCGGLAYLATGDVVARILDVSDRVKFFWIDDVFVTGILRELAEIEPFYLNLRYLYDPEEYRNWLLPAGTLPNDNNNSNSDNEDKKSQQRLRKFPFLFAHIERGDKFSEEMNDLWRKTLRSWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIM5</accession>
    <name>A0A1D2MIM5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nitrilase and fragile histidine triad fusion protein NitFhit</fullName>
            <ecNumber evidence="3">3.6.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_13900</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Cleaves A-5'-PPP-5'A to yield AMP and ADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = AMP + ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13893"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the UPF0012 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.29" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01001151">
        <property type="protein sequence ID" value="ODM92781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIM5"/>
    <dbReference type="STRING" id="48709.A0A1D2MIM5"/>
    <dbReference type="OMA" id="GWHNKKR"/>
    <dbReference type="OrthoDB" id="680339at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047710">
        <property type="term" value="F:bis(5'-adenosyl)-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000011">
        <property type="entry name" value="Fragile histidine triad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000005">
        <property type="entry name" value="nitrilase homolog 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF27">
        <property type="entry name" value="DEAMINATED GLUTATHIONE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="15">
        <location>
            <begin position="65"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="HIT" evidence="16">
        <location>
            <begin position="358"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="14">
        <location>
            <begin position="451"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="11">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="446"/>
            <end position="449"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for induction of apoptosis" evidence="13">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00057461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM92781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="57907" checksum="9FF282CCBE360D0F" modified="2016-11-30" version="1">MKSFSMLRSVQQELRFLFGFLRNYHSTSPNNLQPLQHSITAYNKSLWANCRNFRTKMGSEGLKPVTVACIQLCCTEDKTKNFETARSLICQAKEKNAKMIFLPEAFDYIGRSKEESAQLSETLDGPLITSYRNLAKELKVWLSLGGFHEKQTELRDGLLPWMTNNHVLIDCSGEIKSVYRKVHLFDVVIPEDNVNLKESSFIRGGNEIMKPEKTLIGNLGLGICYDVRFPEFSLSLRKMGADVLTYPSAFTVPTGQAHWETLLRARAIETQCFVIAAAQTGQHNPKRASYGHSLIVDPWGRILADAKDDVGIITAELDLNQVASVRKKMPVISHRQAALYGNTITHKYSIPTGESDNETFSFGHVSVKMNAVFLESELSRAFVNKKCVVPGHVLISSKRVAMRLCDLSPSEISDIFTLAQKVQTIMEAIHGASSSTITVQDGKDAGQTVQHVHIHVLPRKENDFKENDEIYERLGDHDKGNNNIKWREESEMIIECNQIRDHIMQNHVNILRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIU0</accession>
    <name>A0A1D2MIU0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001122">
        <property type="protein sequence ID" value="ODM92899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIU0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="67" mass="7692" checksum="CFCE33A7716F7D5B" modified="2016-11-30" version="1">MPIQKWKETVLYGCPLSHPVHRGCKEDQCGICNSRDIRDREFNALVDNPTGSDLVIQGKRKRTQRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ26</accession>
    <name>A0A1D2MJ26_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tubulointerstitial nephritis antigen-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001105">
        <property type="protein sequence ID" value="ODM92973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ26"/>
    <dbReference type="OrthoDB" id="3789175at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001212">
        <property type="entry name" value="Somatomedin_B_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00201">
        <property type="entry name" value="SO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50958">
        <property type="entry name" value="SMB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMB" evidence="2">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11208" checksum="D4DF5BAC4F7D0609" modified="2016-11-30" version="1">MVVTASAQFGRFADIQGDYCSKRIGGCCPGRVDDCSTPILGTLCYCDHFCNRTDNPDCCPDYWSTCLGIEYTKPPEEIVLDEHHTIPAREGDGEQGEVGVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ32</accession>
    <name>A0A1D2MJ32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001117">
        <property type="protein sequence ID" value="ODM92931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ32"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904113" evidence="2">
        <location>
            <begin position="18"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="204" mass="22142" checksum="D4016766F3E86D86" modified="2016-11-30" version="1">MKAVLSIVLALAVAAQAGVLTTSHQIHDITLSSPVVHHVAPAVLHTSSSLPTNWLTDNFIMKNTFAYREVTALLVAVTIIPYILVFSNGLTTRGVNSTSNDIDLETLSLFGVTPEFAEQFRLNLLKAIELEEKGERDQLRQEFGGVSGGFYQGGNAGAGGAGSAVGGGNQEEDGDEEDEKMLDQQHQDRERLVYYPVSLEYFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ51</accession>
    <name>A0A1D2MJ51_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001088">
        <property type="protein sequence ID" value="ODM93058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ51"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="18134" checksum="4041685923AEC344" modified="2016-11-30" version="1">MENGCLVCTCPVCNTHFRLHDGIQLFLSTRRVQRVAPHWREAGRTLRSEVASLSTKTQSLMAKNKSLKAITRLQNGAINDLKTMTHSQREEINSLQRENRYLKLRRQSLQKAVADAQTTLQSTNEPEIDGNDFRTKIKKKNNSSLPKKTGGAGPHRILVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ63</accession>
    <name>A0A1D2MJ63_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_13613</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001081">
        <property type="protein sequence ID" value="ODM93070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ63"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ63"/>
    <dbReference type="OMA" id="NCAREPK"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="5"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM93070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="493" mass="56868" checksum="98F2EDAEE2836803" modified="2016-11-30" version="1">MIDFFTTFFIVCIALILWWIVEDRRSTANLPPGPPRLPIIGSLLSITFKSELPSITLANLSKIYGDVVHVKMGMSSKVVFSTYEAAKEILDHDKANETDLVGIIGDRNMHQNMGIVWASEEVWRTLRRFTIRTLRDFGFGKAASMDVVINEELVKFLRHFNRTLNSNNDNKMLVTKELFAMSALNVLWRLVTGKSYELGNERLKELLRLSNEFVNASTYCGDISTIFPTLRDWLPDYFTGRKRIEKCIQKLRDFARIPKRLLMYSLQKEENQKSNLNDEQLIYTLLDLFQGGADTSSNTLTFALLYLTLYPDIQNKVHEELDAVISKDAVITVEMKSKLPYCSATLLETLRYSSVIPFAPNRVAVDDFQFRNYTIKKGTTIMVNLHGLNVDEQIWGDPLVFRPERFLTQEGEIDKGMAELVMALEEGDVGVLHKILEKPQFSCISHPSSDTLNWKRRLMEMRNWLLPQSQLLAWDTQQNRLKQRLPEKSEFIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK53</accession>
    <name>A0A1D2MK53_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000986">
        <property type="protein sequence ID" value="ODM93446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK53"/>
    <dbReference type="STRING" id="48709.A0A1D2MK53"/>
    <dbReference type="OMA" id="FRCVAIY"/>
    <dbReference type="OrthoDB" id="9979716at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055470">
        <property type="entry name" value="DUF7042"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055471">
        <property type="entry name" value="DUF7043"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055472">
        <property type="entry name" value="DUF7044"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255:SF9">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23069">
        <property type="entry name" value="DUF7042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23070">
        <property type="entry name" value="DUF7043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23071">
        <property type="entry name" value="DUF7044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7044" evidence="3">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7042" evidence="1">
        <location>
            <begin position="104"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7043" evidence="2">
        <location>
            <begin position="322"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="673" mass="74919" checksum="3E1040CCCBFFA516" modified="2016-11-30" version="1" fragment="single">SEGCHLPSHWEGNWFQSGVHQTITITRNTINTKGRCVEADGEKYLVYNERDDCYRCVVFHEKHYNVLQYKETFCLTERRPVRSVCSTITGDANLFAMFRLDAKSIDCPFRAPLSFTYNRGHGECRYPVSSVDSCTHPSRLLLNYQACPDVPGTESTVEELQCLASWKEGSSRYLLGLIKYQHHASFEERFRCFVYEKIKKGLPVVGSVIGGERSGVGGNRGLHHASAQQHHQAMLMQPMQQLQQHQIINHNMRSIHLSFNSSASALHSSSSYPLVGLPAASSLMMDPNVMFRVSQSGDATCNGLSILEGSRTMTFRRVQAPKPCHFPSWLQIHPQWHTLDLRSTFSFDSSNLKVTNSSSPSPSFGDFFGSVGSEPVSPSSNILTMTASCSQILESSASDRVRLILHTTSGCHSGYMCTEIIRRDSHIIEIQMGSRTRRAEDACHLSSFNQSLLPYITLVSPTPSRKKCPSMGRFGVTGLSREGRLVSDACSEGFTSITVGCRRHDTLQLRSECAAKDVVAEYSCHGWWEEHGVSYLITTPLSRQSGASRYCFIFREVPSLSSLESKSRAAPGGERPIHQKLKLSRGYLEEEEVDMAEDGDTDLGRVLQFSSIADSCRRGVAPGVEGFLAFNVSSNGRCGDVSRAANPKQHHQYHRVLALIFLQVGGMVLIRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLD2</accession>
    <name>A0A1D2MLD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000927">
        <property type="protein sequence ID" value="ODM93722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLD2"/>
    <dbReference type="OMA" id="NCTHYIR"/>
    <dbReference type="OrthoDB" id="10435917at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="189" mass="20578" checksum="7AC668109E5C09B5" modified="2016-11-30" version="1">MAPERRYRRASSRWLRPNYARHLDETIAGQSMRRVMDSYCPYCATDIRAVGPRRMVRCPNISLCGKPLPLDENTCPNCTHYIRTGDNFCRVCRTNLRNVIRGRGGLYQQLHRAPSPLRNTSPPRPEPSEAGDESSSEEEGEHGVVEGDAGNQGPANNIGGGGGEGGRNRAAVGQGGGGFLRVVAIDDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLH3</accession>
    <name>A0A1D2MLH3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">A-kinase anchor protein 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000899">
        <property type="protein sequence ID" value="ODM93870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLH3"/>
    <dbReference type="OrthoDB" id="6263678at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20379">
        <property type="entry name" value="Tudor_dTUD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tudor" evidence="1">
        <location>
            <begin position="102"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="466" mass="53189" checksum="1F99742239A7A37D" modified="2016-11-30" version="1" fragment="single">MTMTSVDIVVGGEDQPKVEGDNVDASHFFETSPIVRASLQDLLPAESLKNILGHKFRIVDYALDKFNEVNIMSVEVKSDEEFRLNEEILDIVEDTDLTLGRVPAVKEVVLARKPKDGLYHRAIVVKTEEAAQAYVYFFDVGGFETVKIGALKPVNEEIMTFPILGYHVLLQDVSISHKLVLKREHSTLMKRMERLVYNLKLGDPISNAGAFTEQNQVTLVSCASKIDLTKEIRLLKVWEWEKFSCGNGTDDEVCEKGAYGKAFRMRTGNELITTYNLRQGMEFTAEVSRVIHEQGSEKTILRVGLLNIASWLDSFNVLHNQMQRYAALITKCPFYPAIGEYCMFKLANNPDYKMHGIKVLGKWCRAIRSDVHVMYLMDLDHFIPYQNLPDEDYDIRRLYAEFSKIPMLTVALIPQENGVDMRFDKASEIFQPKKRFQFKITDAKEGENGLDGYCAEYSLIEKSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLX3</accession>
    <name>A0A1D2MLX3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rap guanine nucleotide exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_12676</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAPGEF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000873">
        <property type="protein sequence ID" value="ODM94003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MLX3"/>
    <dbReference type="OMA" id="FRNFNSM"/>
    <dbReference type="OrthoDB" id="21144at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF249">
        <property type="entry name" value="RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="6">
        <location>
            <begin position="248"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="9">
        <location>
            <begin position="397"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="517"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="8">
        <location>
            <begin position="678"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="5">
        <location>
            <begin position="794"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1009"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1113"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1216"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1009"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1030"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1045"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1113"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1141"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1156"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1219"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1246"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1264"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM94003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1318" mass="147845" checksum="CBE846B100F910E6" modified="2016-11-30" version="1">MDGAEKMMLVDMAFLKSLKRDPERRTDADIQTIYYTLRSLQCLSRLSPEAIYQIAQTGYYWKKQANDILYCRGEIAHCWFVLISGSVFIDGSMFLPITSFGRRASPALTRRPNECLILEPSEMIAIDYIDYYETGVQQTQHRASVSSNSSSAYSGSDTIGSSDHSSKNQNAQIMSSSDNIDLSGLIESTVDSDTDDDVEDDEDDEEEDDLISPYMVRDCVRECLEKDPSERTEHDISVLMEFTQHLQAFNDLTMTVRRALCASMVFAVVEKSNTIVLSDGEELDSWSVLVHGSVEVVLPSGETQVLSAGDSFGLPPTLDKQYFRGLMRTRVDDCQFVCVTQEDYFRILKQGLDNQTTVYDPATNRPVLITEAKLIDSHAAASHTAIFKQQNVLLQPTGQLVIRGTIDQLLNQLVSQETPSVDPTFVEDFLLTQRIFMKPVDLISKLIEWFHDTSIRDRVTRVVLLWVNNHFVDFEFDKELMAMLQRFHSLLEQTKELMSGQLRLLQIACSAKSRTRTITLTRASREDPLPFNIMGGADNGYGVFVSSTEERADTLGMRVGDELIQINSITIRGNTLSKTFELLRGSTHLVLIVKSNFLGHYECINSTTPLLPVQIGENYTESEKNQHHRFLLQHNQNTKTKHRIKKAIWRMIKGETNPDNPDETTTIHTQEYAKIDFPENVLKIYRPDQSFKYLLVNKETTAREVVLLALREFNEPAPVERSYALFQVSCVQPTEKQFMLKQTRLPDHLDCLAERIPLGARYYVKRSDSTDPLIQNEMLPELYKESEVTLLQLNPVELALQLTLEDYAAFRQIEMTEFIDELFTLNSQFGTPNLKLFAELVNRETFWVVSEILNERTSAQRRGQVIKRFIKVATQCRDCRNFNSMFAIISGLGHTAVSRLKSTWDKMSNKHRRLFQEMQDLMDPSRNMGRYRSLIAQSQGQTPMIPFYPVVKKDLTFIDLGNSTHIDGLINFEKMRMVSKEIRSLTQMSAAPFDTSTQPTMAAMNQLTVSSNSSFNNNPLTTTTGKGGRRKDNSKTESRKSKSGSKGGSAGGGGSTGGSGQVVVKKSSGAPNPKKMYEEMNMIRKVKAYLHRLKIISDESVLYDMSIAIEPAPNQSSNSGSTNQLNKPSNQHQHSFRRQPSPTLSTSSSASSESTNRINNNNRKFGTGSPGSYQKLLSLSEPGKTKIKGSSVEKLTGIVSPASLRKLSVPVSLTTPTIHSSPSTGSFGSTSTHHHSTSSADIRGISGSLSDSSSSLSSNNNSSSHHHLHASSHVPQHHHHHHLHLHNSNTRLILNTESSSVLPASNNKKNEQHNVSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN09</accession>
    <name>A0A1D2MN09_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 4B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12233</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000803">
        <property type="protein sequence ID" value="ODM94439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN09"/>
    <dbReference type="STRING" id="48709.A0A1D2MN09"/>
    <dbReference type="OMA" id="LINACEM"/>
    <dbReference type="OrthoDB" id="1748655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12402">
        <property type="entry name" value="RRM_eIF4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033107">
        <property type="entry name" value="EIF-4B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF2">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="94"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="387"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="463"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="506"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="567"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="717"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="739"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="783" mass="86520" checksum="FF64035BFBC6E57F" modified="2016-11-30" version="1">MSSKKNKKSKGVTMSLQDFAMRVEEGTGAPTPGTGQNVVYAEKKPKMPVMSSWADEVEEDGSFFEKERIILPSAPRAARGPAYADHEIPSNPPFTAHLGNLPYDINDEEIYKFFRDLEIADLKLPRDQQTNRLRGFGYVDFHAREDLIEALIRNEQMLRGRPIRITLGTGQRGGPDMDRSGMRGGEDRRRPRGPPPEDEDIDDWRSMMKPQGFDEAPSQEFRRGPPSGDYGSMPRREGGGYGNRERRDYGPPRDRPEEIEFSRDQMMAPPPPSSREGGGGYDSYGGGRGGGSRGGGGGYQSRGGDRDRDYYGGRGGGEGGGGRRDYNRGGDEPYYREEVVVVEAEDPLIITLHPAIIPSRVRTELVVGVDPNNKMYLSLAKALRKITRRRQSPDNYSGHRSDEEDDGGSVSPQGPSEERREREREQPKERKRLVLQPRTVDKPPGESEPQANASIFGGAKPVDTQKREREIEEKLEKLKVEEPPKEEGQQEEEQGSGSDGGGASSHSRETRTTPPRERREPRGGDSSMGSERGSDRDRPRQFRLLTRNNSGNNGKDAYVDVEAPYESVKGSSASGSSSRSHLNSRPPPSSSQGYNPRFMRSDDKDRERGGDRGTYSRGGRGGSREMTRRDMEGGPGRRDFGDGGSRGGRGDFRRMEGGGGPGSRDQDGGRGGGGGRYNDGGPRRGGYSDRRDDEPGLRGGGGVSGGYRDVRDDFRRGPPSSSHHGHHPNNNQSSSVGSQEERDRDSHSEPEDDRDMIREVAAAVVEEETKEENFQMTLQILQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNA7</accession>
    <name>A0A1D2MNA7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000786">
        <property type="protein sequence ID" value="ODM94570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNA7"/>
    <dbReference type="STRING" id="48709.A0A1D2MNA7"/>
    <dbReference type="OMA" id="FCEMEIF"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-4" evidence="1">
        <location>
            <begin position="47"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="306" mass="35050" checksum="C52F6A97C707B8EB" modified="2016-11-30" version="1">MIIKFLWHLTSDGFLRNEYSSSKFTWTCFGSSNRSSLWRCKEFDHLEPPKNWNDMELFCGGRLQQYEVNDGKCGVCGDPFDEPVLVPMRMVRDNCESLSKWCVIPVEVELTTSHKGWFEFKLCSKEDTASHLDQACFDEHPLELADGSGTKYKVPIEGGYYYAEYNLTLPKEVTCEHCVIQWHYETGNSWGNCTDGFGALGCGQHENFRGCSDVTILPENTKHLERNPNSRFGPGEDEFGEIIPMTYHNAKRRCNRTTGGWEEAKTESVISDSDFCEMEIFRPPLLSQELGLERNVHEPAIHTARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNM3</accession>
    <name>A0A1D2MNM3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Death-inducer obliterator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000767">
        <property type="protein sequence ID" value="ODM94690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNM3"/>
    <dbReference type="STRING" id="48709.A0A1D2MNM3"/>
    <dbReference type="OrthoDB" id="784962at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15552">
        <property type="entry name" value="PHD_PHF3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="299"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="49"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="369"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="411" mass="44890" checksum="05F62A487FF865F9" modified="2016-11-30" version="1" fragment="single">GREILTEALGEMGVVPDSAGQEQQLYHSYTAGGKLGKDESVVSSSSVSVCSGVSTTDSPSSTTQMNAGFEESTMTPGYRGRLSGRLSSATASSPRGGKGSVTPVSRNISESDSANIRRSQRQQDRIERQEAERILAENQQMLQREKEIMAKALTVSSPSPVTPQPPVNVGIVSSTQTIVSTTPVTPHVVTPVPEVPRTTPVVDSTTRLSVSTVEKLDDSNVRRPIRNRKLPAHLADPNYLSLEDATTAVKEATRRLSTTQEAVQPVEEIIPPQEEASDGLEDETKEEIADDYTEDDPNRLWCICRQPHNNRFMICCDRCEDWFHGKCVNVTKSQGKAMEIKNIPWHCPDCKKNIAAEKKAEVQVVVTQKQVKQQQQQQQSVVPEKTGRGRKSETQTSPKLVSAKTAKAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPH4</accession>
    <name>A0A1D2MPH4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sortilin-related receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000733">
        <property type="protein sequence ID" value="ODM94933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPH4"/>
    <dbReference type="STRING" id="48709.A0A1D2MPH4"/>
    <dbReference type="OrthoDB" id="8251576at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="22585" checksum="1A6D82B7E0016CF9" modified="2016-11-30" version="1" fragment="single">FSRLTVSTNAEGGRQSAPVYFDGPAIPFPEKIQECSQCIPLTIYWEQPKLPLLVTKKGQESYVVELSKDSNFTNAKQYETIENSFKFDEIRDDGLYYVAVRVRDHEGLLSPRSNAILVQQSGGASPIVVIPGSSALAITISVLIVIVLLVAVLGIIIVRHKRLQMSFLNFASSHYSSHSGAATFQQTVDEQDSPVIRGFSTTSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQA9</accession>
    <name>A0A1D2MQA9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UNC93-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11449</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-93 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000695">
        <property type="protein sequence ID" value="ODM95223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQA9"/>
    <dbReference type="STRING" id="48709.A0A1D2MQA9"/>
    <dbReference type="OMA" id="TSKCAYL"/>
    <dbReference type="OrthoDB" id="78663at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055120">
        <property type="term" value="C:striated muscle dense body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015459">
        <property type="term" value="F:potassium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006937">
        <property type="term" value="P:regulation of muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043266">
        <property type="term" value="P:regulation of potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000290">
        <property type="entry name" value="Unc-93 homolog A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051951">
        <property type="entry name" value="UNC-93_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444:SF13">
        <property type="entry name" value="PROTEIN UNC-93 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444">
        <property type="entry name" value="UNC-93 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="488" mass="54110" checksum="220FD37A252F8E42" modified="2016-11-30" version="1">MSFLNPAYNCDEDVDKSGKCLAIKIYAHNPHQLSCTPSTTYEPGEGRRMWKNVILTSFAFTFLFTAFQSMASLQSSLNSGGLGTYSLSVVYTSLVLSSMFLPTFLIRKFTVKWTLVFAVFGYSAYIAAQFQPSYATLLPGAVIVGVCAAPLWSAKCTYLTHVGHQYAKLTGASDAEPIIVKFFGIFFLFFQTSAVWGHLISSVVLSTDSRMCSNDIASQCGVNFCPDTKFCDSNINSTVTGEEVQPSTRYTLAGIYLTCSLAAAVILAVFLDPLTRYGEKERTGSSSKLEGKDLLVATFKHMTKPYQILMIPLTIWSGMEQGFFGADFTSGYVNCAWGIEKIGWVFIWYGIVDAIGSASFGPIIKYTGRVAIFSFGAIVNISMIIVMLIWKPNPENPVMFFVVAGFWGIGDAIWQTQINAFYGVLFPHDEEPSFSNYRLWESLGFIIAYVFSNVLCVQIKLYILLAVIFVGMIGYFIVEILERKNQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQP2</accession>
    <name>A0A1D2MQP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High mobility group protein DSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11350</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMGB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000685">
        <property type="protein sequence ID" value="ODM95316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQP2"/>
    <dbReference type="STRING" id="48709.A0A1D2MQP2"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF32">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="82"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="182"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="82"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="182"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="30058" checksum="3C9A87839F01B199" modified="2016-11-30" version="1">MSKVAETPIFDIKITEEMKWQSKAHCEYIYEKVGQTYIHVGRESVDNWIRIPSDFRTTGESLCPGNSSTQGFTMAEGQVPQPRAASSAYACFMQHFCHQVQSTGGQQAIISSDLSKVASERWKGMTEDEKKPYKELSNKDKARYQQEMARLNPGTLVTVTSTTTGRKRKLGSRKAAKDPNAPKRATTAFFFFAQVERSKVRAEHPEYKVTEVSKELGKMWGLMKPEEKEQYEQMAVRDRERYQHELKKYNASQEGQGTESEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRC5</accession>
    <name>A0A1D2MRC5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000647">
        <property type="protein sequence ID" value="ODM95593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRC5"/>
    <dbReference type="OMA" id="IQDWRNP"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="23544" checksum="9ED40678926F14D3" modified="2016-11-30" version="1">MEEGTLKKTRPATPVKWQHPNNHLPHTRQQRRRSDESGFCCARMICRARFVAILAVLLGVAVMGTCGWVLHKAIQDWRNPTLKTASVLLSQVNTFFGGTTGLYDLDVIYTILTSCSATGFVGGVLQFLLSMWLFLALVKDGRAVSRVWVMAHIVIMLAVGGAFLCIITNELEINDAITALLIVTGIDFILLIPFSLLFFMYSTQEDNGDTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRE1</accession>
    <name>A0A1D2MRE1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000667">
        <property type="protein sequence ID" value="ODM95468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRE1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904428" evidence="1">
        <location>
            <begin position="21"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="211" mass="24129" checksum="2D599348E499BEB0" modified="2016-11-30" version="1">MKTLIVLGFLLVAFLSSVICEDAIVMTSEKLEQFLRSMPESKKLSYPEVIRAINGKMYYRNPKSLKPQKRIRNIKLNQFVTLGNDRTGNKTSSFVHLTYSDRSKFFVLNGGDGKPGKMLLEAFSQDGACLFGVSEAHTAVKAKACRKDVPEMRWELIPNTFGDYWIKQMGTKLCLVPVLTMSYPTMVQLLPCNKWDPYMIWEIADAMLYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRX5</accession>
    <name>A0A1D2MRX5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Guanylate cyclase</fullName>
            <ecNumber evidence="3 14">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_11003</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>GTP = 3',5'-cyclic GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13665"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57746"/>
            <dbReference type="EC" id="4.6.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="3 14"/>
    <dbReference type="EMBL" id="LJIJ01000635">
        <property type="protein sequence ID" value="ODM95682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MRX5"/>
    <dbReference type="OMA" id="PTDEPMC"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06370">
        <property type="entry name" value="PBP1_SAP_GC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000019">
        <property type="entry name" value="Guanylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF474">
        <property type="entry name" value="RECEPTOR-TYPE GUANYLATE CYCLASE GYC76C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="614"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="17">
        <location>
            <begin position="924"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1132"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1201"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1345"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1457"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1539"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1597"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1148"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1201"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1364"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1401"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1417"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1458"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="1539"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1551"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1604"/>
            <end position="1618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM95682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1618" mass="181060" checksum="5FBDA975267BB152" modified="2016-11-30" version="1">MERVTPLEMKTVWLVPVRVARVKSVLKGAHSFYLCSLGLFLLILSQAHVVESVTPPEPSHLPSGNDENYGVPNNVKENLTIGYLTAVKGSVPYRQGITISGAILLAMEKVNNDSSLLPGANLVLKYGDTEGDTIKGTKLLTDMLCEDVAAYFGPEVSCHVEATVAAAWNRTMISYRCADSTVSDKNKFPTFARTEAPDTQIVKSVLSVMHHHHWKTFSIIVEDPSPVLVASSTKTTQYTIVAETLEMFATANSYKVTNRTHFTDGNPNWYEIVTSTMNKTRIYVFIGQDKNLIEMMGTMHSLQLFQNGEYLVIFVDALTYSRREALRYLWRHQDIANHKHDVSCDKLPNFDLKLSRSLLVVAPSPPDHTYENFSNQVNEYSKRPPFNFGNRLLEKVGFNKPKEVSIYAANLYDAVILYAQALHNLQSKQQSESIQVLARDGRAIFKEIIEMKVYNSITGAKISIDENGDSEGNYTLIAFKPLPKDAPFFREMNINFTCPYYMIPVANFQPQPKAENITYPRMKLFTGQQIDWIGGKKPSDEPKCGFEGEKCHGPAQGYRPVITAGILGFILFVVISAAASLYRKWKIEQEIEGLLWKIDENEISVQQPFGETSQSRMSLVSVGSLGQVYCATAHYKGALVRIKELKLMKKHVISRQTMKEMRYMREMCHPNINSFHGAVISPTKITLAYDYCGKGSLTDVVENEDIRLDSTFIASLIHDLIKGMMYLHDSDLAFHASHAYYQNMLWKAPELLREKAFAQGTQKGDIYAFAIILYEIYGRKGPYGMCEFDPKEIVERVRDGREGDYFRPDTNFLDECSTQCPEFVITLMTECWDELPEGRPSFRIIRERLKPLKEGMTPNIMDHMMLMMEKYANNLEDLVNERTGMLVQEKKKTEDLLHRMLPPPVAERLTLGEGIEPESFDSVTIYFSDIVGFTQMSSESTPLEVVNFLNDLYTLFDSIIQGYDVYKVETIGDAYMVVSGLPLRNGHQHAGEICSMALDLLTAVHSYRIAHRPHETLKLRIGIHTGPVVSGVVGLTMPRFCLFGDTVNTASRMESNGEPLKIHISDECKQMLDKIGGYVIKDRGLVHLKGKGNVRTYWLVGACEGAVLSRRADMKDLKPLFCRPRGLQSLSEQQNLRRRASPKLPGSGNVSRQGSFCAGSGQTNSHLLSNQNRGSTHYIRRPSFDPALLSLSLKAAQQQMVHSSNSNVQNPATGSYYRSASRESPCGTPTRKRKEDHLTVEKNCQRPGECSVTIEPPSDSSTAHTPMASPLRTVALPVGASNSANNLPQSSSDHKLRDLVHRKKLGFPPRLKLNQGLMREARSLDVLVCRESPVETLHPRSPAIKMRRMSKSVDIDDGNPLSAKELDNMDQQQRDRNSHPVCGGVDVENSSPKTKRATMPPTLSSALTSKDGSTGKLHGKRPTHNRNHRNQKHFQNRSSDSFSCDSDDKYEAAFLLDPNSSFDTKSNQGEEEDECGPVSHDELEEGHISMRVNICDNPERDGHVRVPKSPHWRKLSDQIEKEKKGSTLKNWFQNILNGNGIGSSGSGGKRGSVSGSVHGSLNTDECKVVDVRPTVGSSLTDEEKGLKPLLRDKIKATSVSNENRSSDVPHLLENESVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTS0</accession>
    <name>A0A1D2MTS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Striatin-interacting proteins 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STRIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000549">
        <property type="protein sequence ID" value="ODM96332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTS0"/>
    <dbReference type="STRING" id="48709.A0A1D2MTS0"/>
    <dbReference type="OrthoDB" id="18234at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040185">
        <property type="entry name" value="Far11/STRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021819">
        <property type="entry name" value="Far11/STRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012486">
        <property type="entry name" value="Far11/STRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239:SF4">
        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11882">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07923">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01293">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01292">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Far11/STRP N-terminal" evidence="2">
        <location>
            <begin position="83"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Far11/STRP C-terminal" evidence="3">
        <location>
            <begin position="422"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="806" mass="93074" checksum="AF960433658354BC" modified="2016-11-30" version="1">MATVERVWPNERQLEEPENDIPSLVPICASSVESSDLVDAVNENGCLRNDSEELSHSNVDAAVYNECVEPIKETSCNPDSYENKKIPFVYKDWDTLENELADIYGYYERYNFSSNLKAFNSLLKNRSHHVCKWALLEKADKVNFLHDLLDQLEIADTGKQLEALLAMNYIVQGCWGEYAALSDQLHLTEVNVELLLESDAFWRVWTFFKVVFEKFGNDTLPEENDFTIQFLENSLNVLCTVAIIVMVKTQESGSSPGFQIFIDEIIDLNEDELVIITLLKIFNQIKSISPKCFLVKKVLLLIRSILLLTLGGSDELRRLKESCRKAVGLKPTIEDTVQICRNIEPLQDATMWSGMMARQKLLTWSEFADVVMEETTQTPVCKRSLPWTPKSSIKSLRAYRCLSNALPEESNLHSMQSISSLPVPVKQRIQLIIEYLHVPLANHQIEQENVVSKFPNRFENKPFVDKTEQLFEALLPILEDTVRSLVTVLSEATPRKHMKQRLFVYKTVSTYSSSEDSRRQAQIIAKAIAAVLLLLLKHTKINHIYQFECISSEIVAASFIPTALRYLNRDVEKCIRFHESSQDVSSRYKVMNGSLLYCDQTEDYTGRENVEMESSRVSWRNLFTYINLLRVLNKLLKEKSSRVMMLKMFKAPDCLKRCLKIRDSIFQQYVLKLLKMLCKHLGKEWRRSNQHVVSAVYYKVRHRLLDDWMGGGANASVCVKDTKSWPWEYYEVEKQLTHNVLAYLKRHYVPDAGDENTSTEIQVGDLESSEVKLSETFKLGYEEWLEHEVYTKQVDWDALVKPTFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTU1</accession>
    <name>A0A1D2MTU1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spondin-1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">F-spondin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_10254</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000540">
        <property type="protein sequence ID" value="ODM96426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTU1"/>
    <dbReference type="STRING" id="48709.A0A1D2MTU1"/>
    <dbReference type="OMA" id="ARFSEYC"/>
    <dbReference type="OrthoDB" id="347314at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08544">
        <property type="entry name" value="Reeler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2130:FF:000002">
        <property type="entry name" value="Putative Spondin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.100.10:FF:000026">
        <property type="entry name" value="Spondin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2130">
        <property type="entry name" value="F-spondin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4060">
        <property type="entry name" value="Reeler domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002861">
        <property type="entry name" value="Reeler_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042307">
        <property type="entry name" value="Reeler_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051418">
        <property type="entry name" value="Spondin/Thrombospondin_T1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009465">
        <property type="entry name" value="Spondin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038678">
        <property type="entry name" value="Spondin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044004">
        <property type="entry name" value="TSP1_spondin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038123">
        <property type="entry name" value="NF038123_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11311">
        <property type="entry name" value="SPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11311:SF16">
        <property type="entry name" value="SPONDIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02014">
        <property type="entry name" value="Reeler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06468">
        <property type="entry name" value="Spond_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19028">
        <property type="entry name" value="TSP1_spondin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51019">
        <property type="entry name" value="REELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51020">
        <property type="entry name" value="SPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904546" description="Spondin-1" evidence="13">
        <location>
            <begin position="32"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="domain" description="Reelin" evidence="15">
        <location>
            <begin position="19"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin" evidence="16">
        <location>
            <begin position="199"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="14">
        <location>
            <begin position="660"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="732"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="732"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM96426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="870" mass="96735" checksum="B2E38D73100E1E7A" modified="2016-11-30" version="1">MWKRGEDSRFVKLPLLFLLLSFGCFVVSVDGLWCDRAPAGVNVPKSPGDDGYKIAISGDPDKPDKYIPEAVYTVRLQGPGDQYTVKKFSGFLLVAEPADGLSPETSAGSFQLIGDSLARFSEYCPHAVKHASELPKAEVQVRWTAPPASAGCVSFRQVYNFTLFWATIIKNKGKWFMDDGELTKTLCPETDVGPDESETSEPCCACDEAKYELTFEGLWSALTHPKDFPADAWSAHFSDIIGASHSPTFRFWKKDGIASEGLKQFAESGDSKDLESELKAESGSIRTIIKARGLRHPNFYGHKTFAVFRADKEHNLISLVSKIAPSPDWFVGVSGLNLCMKNCSWLTNKVLPLYPWDAGTDNGITYLSPKESTIPRDRIHGITWQEDDRSPFFDASGNMVKPFARLRISKQRSYEKTCPEHMEKHGAGLGRAGGGDYDEDDQYDDFDDRDRPECEMTDWSMWSTCNSAASCGPGIEKSYRNYKNEAKAIDLGCNRQRTRERQCDVPCSSNYDGYPRSGYRGGSGSSNSAYPVDQGMDPCAVSEFHPWGGCSVTCGQGLKRRFREFLYPSMARSHACDTSILADTERCLGAFPNCMDAEEIRPGCETTDWAEWGPCNATCGKGIQIRTRRYVHPPPHTDCRVDLYDDQSCEGTECTPQEICTQSVDIIKCRGSYTKWHYDVASQTCKKFSYGGCGGTQNIFETKEDCEDTCGSITELPSDSLPGYHHRHQATFQNQNQPSSSSRYHQHHNQQHNSPYSSSYQNYGPVGGGTGRQTSSLSTLSSSLASSSSNSYSSYLPAVDCDLSEWTPWSKCSVACGRGHKYRTRYIKVPSQNGGAPCPNLEHKRKCKGTQCPPNHPFRYHHHQSPSYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVC4</accession>
    <name>A0A1D2MVC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09779</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000492">
        <property type="protein sequence ID" value="ODM96892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVC4"/>
    <dbReference type="STRING" id="48709.A0A1D2MVC4"/>
    <dbReference type="OMA" id="ICHESFP"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="466"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="586"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="646"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="676"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="704"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM96892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="737" mass="85758" checksum="16C39B7B3A343F70" modified="2016-11-30" version="1">MALKGVPHRCLICNSVNSNSLTQHENSEKIAEQLKVIFLLRNVLEVPKENLSTYLMTWGSPQFWIASCSKCNKLIDEARSVYDDMLSSLNRFRVVKQKIVRTIKRSSIDAEPLGYSHGVTKLLITNQTRQFVNIHDYGNFIDPFVTGDRKANQILQNKEWSALTNAVEVKEEVVLDSYVEEDLDDMHNPVERNGNSIMLNDDFIAMNDGLKGESSTLTHESKKTATIVKDSNNEETEDDDDAELFDGHDDDWNPEIESRQNTKNAKNEFQNHVVDQNSIFCPLCKIFKFCIEKREKFCEHLEICKGNSDDNEASQVLNQCCPMCNTYKFSLDGKSDFIDHVMLCKGIVTESSEMTLHDRIFKCSVCPLTKYMRLNTFLQHFLFHKKNIYKCSKCSKRYHWNVGLNYHWRANHKDSTNVPSSERYITDFSVPEVIWWCAVCNQTFPDSETRDVHLQTIHQKEISKTHQCPECSEGFSCNEELKLHQGTLHVSSTSSYTCDICHESFPTATLRRQHKRSKHKDRIGHFVCEICGISCSQQHILNMHMQLHQEVRKFVCECGKSFTSRQYLRNHKFREHVAADEKINPLACKICKRAFHSTTYLQKHIMAVHEKKNRFFCHLCARGFMEQNKLNRHLMMKHGIGDLKKHVCPVEGCNKDFWNSTAFKSHLSRHRNEPRFKCGECGKEFFSSGHFRRHEQIHSGVKPYKCEICFKSFPVRNYLYIHMRSHNKKNQGETVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVK2</accession>
    <name>A0A1D2MVK2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Chromodomain-helicase-DNA-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09621</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Protein modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000476">
        <property type="protein sequence ID" value="ODM97046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MVK2"/>
    <dbReference type="OMA" id="HCTWESE"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18659">
        <property type="entry name" value="CD2_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000744">
        <property type="entry name" value="Smt3 activating enzyme 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040793">
        <property type="entry name" value="CDH1_2_SANT_HL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025260">
        <property type="entry name" value="CHD1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18375">
        <property type="entry name" value="CDH1_2_SANT_HL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13907">
        <property type="entry name" value="CHD1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01176">
        <property type="entry name" value="DUF4208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Chromo" evidence="12">
        <location>
            <begin position="316"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="419"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="936"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1227"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1413"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1652"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="952"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="973"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1227"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1254"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1284"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1413"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1428"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1451"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1481"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1675"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM97046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2095" mass="235747" checksum="C2D45EB85E9306FA" modified="2016-11-30" version="1" fragment="single">SPKMSSSSRDSSISPPPKMVKHGGGKSSGSGKRRDIESDSGSEDGDEGNKNVSNNSSKLLSSTDSGGSGSSASGSDSESGSEHSEEEEKVVEEELGEDDDDGERSRHSSEDDEDVIDDEKSRSSRSRSRSMSGSGSGSRSGSASSRSGSGSDSDKGENSEDVKKLWEKDPEMFGIRRSGRKRPSTESKPPKLVAQVKSKKSSPTKKSSPQSSSRKRKISTDDEDDSSSDEEVTRNVRTRNNVVSYKEDESDDPADLMSVDEDEESKDIPEEEEELVDTIEKKEDDHRRWKDYACIEDVEYMECQLELQQELYKAYYIPDRIIAERPGADGTAEYYVKWECLPYADATWENAKLVQSRCPEVIQKFKRREASNQTPSSSTKSLRHRPKFSTIKYQPSYMVGEEKNLELRDYQLDGLNWLVHSWCKENSVILADEMGLGKTIQTICFLSYLFETYQLHGPYLVVVPLSTMAAWQKEFTQWAPQINVVTYVGDVGSRDIIREYEWCFRDSRKMKFNAILTTYEIVLKDKAYLAQLPWAVLMISRLYMIVILVHIPMYRLLITGTPLQNSLKELWSLLHFIMPYKFDDWEYFEKEHDHSATKGYSKLHKQLEPYILRRVKKDVEKSLPAKVEQILRVEMTTIQKQYYKWILTKNYTALRKGVKGSVTSSVNVVMELKKCCNHASLIKPIDSAQDTLTTLIKGSGKLMLLDKLLVRLKETGHRVLIFSQMVMMLDIIAEYLQYRRFSFQRLDGSIKGDMRKQALDHFNAEGSQDFCFLLSTRTSSCSQNRAEESGQHLQTSHKELGGGRYCRASQEKNGFGPFGYSAYGHDWRTVLDKGSKSNTPFSKDELSAILKFGAEQLFQEDDHEGDDQCDIDDILRRAETHEEAARPGDELLSAFKVASFSMNEDEADISEPVSTKREVKDWDDIIPEDLRLKVEQEEKEKEMADLYLPPRSSRSQTATDKTPLTLGNEALNKKARGKKRKFKNESDDSDYEDDDGRPKKRGRPKGHGREGLKGFTEVQVRKFLKSLKKFPCPLTRIELIADDSGLTDKNLADLKKLGELLINGCKKAIADQKANHQVVVKEETISSPPDSAIGEDGVADKKKPQKIREKGPIYKVCGVNVNARTMSIALEELEPLADLVPFEESQRKQWKFDLKAKAATYDIDWGAEEDTRLLLGVWEHGMGAYDKIRESDPVLKEKIFIEGDKKPTLKHASQRADYLLRVIKKHQAIQKTKVPKPPKEKKKREPKGKKGKGNSENAENNPNAGKKGSGDDTTVVAADSTGKEKKKRGPRKKKDVGPMHFAAKAEPTPINVLGDLDPVIFNECKEKMRPVKKALKSLDNPDPNMDEKEQIEHTKRCLIQVGDRIQECLVSFPDKELAKEWKSNLWYFVSKFTEYDAQKLHRVYKKAILHRDNKGNEEKEEKDGKHKEKDRKHKKHRKEKDKEVSRGGGLNENSNSSLGDSFTPNKSSKQPYRERSGGAHNKQSFAADNNRAKFSSQTAQAGGVSNGHHPLPCLHGKSAGGHTHSTRNHVVYRDRQRGTAACCAPGTSPRLTVQLLILAIEVGHYPTKLPNFEELEWTTTKSRQRWCKLDKRWENDTPTMGQEGMRLQLPTTMPVPRGAATTIGAPPPPAIGGLSPYQSSSASTVGRIAPPLTQAEWRRSDPKRQFYGNTAPADSVSSSRGKNPNSVSRRDDTYENIFYPSTGHSYEYRLSGSGVKEHFNSETQYKYMRTKYCTTSRREPGTVAVVHCRSIGEYVPVCVDIFGPEEPVKTFTDDEAALYDRQIRLWGVDAQKRLNESKILIIGMGGIGAEVAKNIILGGVKSVKLMDDAVVTQLDASAQFLAPREAVGQNRAEASLQRAQLLNPMVEVSADSSKPENKTDDFFTQFTVICVTNCPKSQACRTNRIARQNGISFFAADVFGFVSFIFADLGEHHYKKELAAQGKGKQKQGGTTTTTSVIDKVAHFVPYQDILNIDWNLEDFAARVKRTQPGIFAVFVLLEFVERHKRKPNPDTSEADVMEILSIRDEYIEKNGLSKEKVDDSLFENVCGELGPVCAITGGQLAQEVVKAVSRKDDPLVNFFVFNPVAGTAFVENFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVU7</accession>
    <name>A0A1D2MVU7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cuticle protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000475">
        <property type="protein sequence ID" value="ODM97072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVU7"/>
    <dbReference type="STRING" id="48709.A0A1D2MVU7"/>
    <dbReference type="OMA" id="HQTESRD"/>
    <dbReference type="OrthoDB" id="6510765at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF95">
        <property type="entry name" value="CUTICULAR PROTEIN 76BD, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="34"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM97072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="123" mass="13396" checksum="84DF06C7F3964660" modified="2016-11-30" version="1">MVSNFLNIRVLCLVMVAMLPIVFSKHGYSHQHVHNPGYGGHGGGEEEEEGWRVNDHYTGDNKQHHESRDGGVVKGQYSLVEPGGSHRVVTYHADHTGFHAKVHRTPTHHGHGVAGGGGHHGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVW2</accession>
    <name>A0A1D2MVW2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Aurora kinase</fullName>
            <ecNumber evidence="14">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_09745</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Midbody</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="14"/>
    <dbReference type="EMBL" id="LJIJ01000486">
        <property type="protein sequence ID" value="ODM96934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVW2"/>
    <dbReference type="STRING" id="48709.A0A1D2MVW2"/>
    <dbReference type="OMA" id="ESRFPEW"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032506">
        <property type="term" value="P:cytokinetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000235">
        <property type="entry name" value="Serine/threonine-protein kinase ark1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="138"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="216"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="267"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="11">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM96934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="398" mass="45241" checksum="E560398568D95297" modified="2016-11-30" version="1">MERGTNHYSEFRRPLEVHKSNREGQVKVSSTTMSNSKPVFAVPLAPAEKHKSHHHHATMSSANLKQAPTQQKSKTETTEGIGIMGPPAAPPSHSRSGAVKQDQNVPSSQQSHTTTGRRSIRLSDDGKGGARRWTLNDFEIGRPLGKGKFGNVYLAREKKSRYIIALKVLFKKELQRANVEHQLRREIEIQTHLRHRNILRMFGYFHDESRVYLILEYAPGGELYKLLTSQPHKHFTEEASANYIHQLASALSYCHSKNVLHRDIKPENILVGTDGEIKIGDFGWSVHAPSSKRETVCGTLDYLPPEMVEGRAHDKTADIWSIGILLYEFLVGRPPFETQSYNSTYDKIMRCEYTFPEHVSSGARDLIIRILKKDPRARLPLDEIIVHPWVAQHVPQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVZ6</accession>
    <name>A0A1D2MVZ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450 83A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000460">
        <property type="protein sequence ID" value="ODM97239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVZ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MVZ6"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24299">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="10153" checksum="3CE57918691D0C47" modified="2016-11-30" version="1" fragment="single">MLGLTEYLLLAVAAIYLAIQFLKPKVKLPPGPRGLPVVGNILQMTEKPHLQLAAWAKQYGEIYTIQLGSNTGIVLNDQKLIKDVLSNTDFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW20</accession>
    <name>A0A1D2MW20_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Clusterin-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09537</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLUAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000469">
        <property type="protein sequence ID" value="ODM97131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW20"/>
    <dbReference type="STRING" id="48709.A0A1D2MW20"/>
    <dbReference type="OrthoDB" id="438545at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019366">
        <property type="entry name" value="Clusterin-associated_protein-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21547">
        <property type="entry name" value="CLUSTERIN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21547:SF0">
        <property type="entry name" value="CLUSTERIN-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10234">
        <property type="entry name" value="Cluap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="399"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="589" mass="65056" checksum="4CA0CA9A569ED4D7" modified="2016-11-30" version="1">MSYRDLRNLAEMLRAVGYPRMVSVENFRNPNFPLVADIGRWLVSQYEPKTDFPHSVETEHDRVLFVRLFAEFMVTKVQVKLNTKRLYQADGYAVKELIKVVSVLHNAMRGSERDPRDAKFDDRPFDMLMHDLKELKGVREIASALTQRGVTLYDLLNKEVSLREIRQAALSKAYEHEEVERLLKGSVQMMSQEMSKLSGMIDSVQSNLASLDGKIEKRRGDLDRSQKRLLTLKKVRPAFMDEFEQLQTELSQVYKVYVNRFRCLAFLQNRIEEMNREDSERKAEEKLNRAEQNSYGGDDFLYSGLKGDGIYSGSDDESSDEMHLLNDANLNLTTGRSSFTSKQSQSGATGIAGNSGNRTATVVGAAASGATVNGLRQPSTMNGGAQSSRARNRQMYGTMMGPEEDSEESESDLILVDGDNDNSELGSDEPDDDDLVQIQKAGVNSGADNNRRSNLTSRQQHFQGNNDMNHYMNGGIGDPPPVPAASTNPSAEMINYGGGGDAYNNYGGMGNGDLSHNTGAGGYIMGNGGPNHSLANGGKGYPVDNLKNGSSSGKRLQGQASRPTTSGKRRGPSQQARRVTDLDDDDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW94</accession>
    <name>A0A1D2MW94_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrase/recombinase xerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000454">
        <property type="protein sequence ID" value="ODM97330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW94"/>
    <dbReference type="STRING" id="48709.A0A1D2MW94"/>
    <dbReference type="OrthoDB" id="6599971at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057191">
        <property type="entry name" value="DUF7869"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25273">
        <property type="entry name" value="DUF7869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47823">
        <property type="entry name" value="lambda integrase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="99"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="941" mass="107724" checksum="1B546861FE699AED" modified="2016-11-30" version="1" fragment="single">KILHASCSSGTWKQYQSVYNSFTKFCESVNQNPLQPNIETILQYLTHLFDTGKGYISINSARSALSTLLGPVEGNTIGNNPIVVRFLKGVSRLRPPTPKYKTTWDSDIVLNFIDKSESNENLSLTQLTLKLVALMLLCSGHRIQTLNNIKLHEIKENGDELVINIENRLKTSKAGVGTTIRFRLFHNRKLCVVTCLKYYIEKTKALRQSEYLLVQCKAPHQRASCQTISRWAKETLILAGVNTEIFSAHSYRHASTSKAAQLGVSLDTIYKSAGWSEHSRVFQKFYNRPMCSETGYSNAILTRKPLEVGSVATSGDNSLYTSNVNLTVSLTKMELNNGAFISAAKFVSMNIQRKRPIHVNDWRDVKAKTLRNSGQPYQSRDGTHRDGKHLPSNDKVCGGRCDLDGCKVDGETKSTLFTKYYEMANLELQHTYLASNMQRFQQGNRNRCRYFLPVGGERFECCQKTFLNVYRVTARVIDTLNRKMLGGDICIRDGRGKHHNRPRKNSQELKQEMLEHIQSYPTYETHYARESHGPVYLSSELSVTKMFQQFCAERPANPEYLKKMGLYSNIFRKTGLKIGQPKSDTCKTCDLIRVKLSTARIDDKAPIEAEQQLHHSRAEAAYAALREDAQRSRDNPAYVTICVDMEQTLFSPKLTHGEMFYLRQFASINYCIYYAATETANMIFWNETDAHRGVDEVASVIIKSLLDKFRQLEPGQERTLVCWSDRCKGQTNNWPFVCSLLYLVSRNIFTRVEQKFLVSGHSFLPCDRLFGLIELRKQDCKVIIPDEWCDVILSAQPSKPFQVTRVVQENIWNVKQAFDAIKKPQNLKVTEMAWLRFDCHSPEEICIRSNHTENAEWISHAFSAPYQVGVRHARRIRFSLAAMNDIRLERKYFVPIPLSHEKLSDIRKMIPYLEGEGKAFFLNLVAENDEDGDRDAIFDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX15</accession>
    <name>A0A1D2MX15_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000428">
        <property type="protein sequence ID" value="ODM97586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX15"/>
    <dbReference type="STRING" id="48709.A0A1D2MX15"/>
    <dbReference type="OMA" id="AINTVMK"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904680" description="Aminotransferase class V domain-containing protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="3">
        <location>
            <begin position="89"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="3">
        <location>
            <begin position="528"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="747" mass="84365" checksum="03BA32AAB660AA28" modified="2016-11-30" version="1">MKYKIPLLNCTLAVAFVIICIQLRESDSTDEVDGPQRLPPLGRSMRREFFMEDNFIFLNHGSYGTYPKAVRTELRKFQEIAELNPDRWFRQDLIKEHTKVREMLAKIVNADAEDLVLVPNTTGGMNAIFRSLVFAAGERILHFNTIYASMGAIIQYLVDKSNGSLSKLVFNVTYPMSNEDLLQKFETFLTKNEDPKHPIRIALIDHISSVPGVVNPVDKIIPMLKQRNITVLIDGAHAIGQVPIDLKVLQPDFYITNCHKWLYAARGTAILYVAKKNQPFIHPGFINAEYSQPAKLQDEFFWTGTMDFSSYMTVPAALQFRKEVGGEVAIMEYNHNLAYLGGQLLASAFNTEVLQEKNQIGSMVDVRLPVDNPDDPKLTPRWWVDEQLNMKYNQTFSPAYRHNGHWWVRVSAQIYNDLSDFDICAQHFLAICNDLNNGSSSTNGSNNPTPDIVSTLFKDVVLVVLGVHSGDGGRKRLPPLGRAMRGEFYIDDDFVQLNHGAYGTYPKVVGKHSEQLKKGKSERNPDLWLRREVKTELAKVREMLAKLVNADSTDVVMVPNTTSGINAVFRSLVFAAGERILHLSTIYNSMGSIIQYLVDYSNGSLSKIVFNVTYPISNEAFLQSFETFLDEQADPEHPIRIALVDHITSVPAVIMPIERIIPMLKARNISVLIDGAHAIGQVPINITALQPDYYVTNCHKWLYAARGCALLYVDKKHQGEVHPANINSGYRQPANFQNEFFWTGLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX47</accession>
    <name>A0A1D2MX47_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monocarboxylate transporter 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000427">
        <property type="protein sequence ID" value="ODM97613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX47"/>
    <dbReference type="STRING" id="48709.A0A1D2MX47"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF251">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="621"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="713"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="744"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1038" mass="115346" checksum="3B9B614CF15AD32A" modified="2016-11-30" version="1">MESLKLQSKQGFVENPNKDNARNSPSTASSVSKLQHVSTQRTLTDSTLSSFTKPILRNRKLEVFAEESEEDAEKIGNDERLRGLENQANCANQQNNVSTTTFIAEFDEKFTAGLIPNDLPSDLFDIEGNLIYGNVDTMRFGLEEEEFSSADENEQSKNYYDLNFRNQRKSLKQEQRKDGFSGRKGKTSQRSKQQGTNHQAKRQEQWRQHESFGKYQHPISSSNKLVSISSGCEQISSQMMEAAKTTRGEIIEPAASDAPYLSESGPVLHGRQSFRKHSSEDVYHPLINNVGRRGRRPKRQFSSRSRSSSGTNANSNSGNFSPPSDQYRSPFAPFDRHHSSGGASSTNSSSTITQHYYPEGGWGYFVLATCTICHVLTCGFQLSFGILWQAILEKFGSELHLISCWLGAVSLGISLLFSPVWVSICKKKSTRLSAVFGGLVASLGCLFTSFASQFHQTFISYGAFLGIGVGLTRDASSLMVGQYFKRKRELVEIIVVSGSGLGIIIMSISVHSAIGSLGWRLGLQAVTVSLILTFFLGTCYRSASLYHPQRRAILHLKNQKRKVKEKGKREDKPPFIDCSCLRSKTLRIILMSSACTAFGIFTPLLSLAVQCSSQGFEDCSLLLLHIYIGTSWVIGCLTLGLIVVQKSQDCRVSKQYLCGQCDMWDLNSGSYSRQRHKWDGGIFLGLWSVSRCYCYSLKVYTYERARARHFPRAWSFLQSSQAIPLFIGVPLTNYANETVGWKSGYYISAIAVFLGTACLFLTDVRRRKLIRRKSQNSSMKTCETTDGGASSPKVKRLSFAFPAEPMVHLQQSKHDSDDEDEPGGPIDPSVMVKELTCISEEGLADVDFQDIYFEEWAEYFGECITSCNKVENCLASEYDPDLAMIVDRRARRWSAVNKHGLGAQQGNSLFNTGATGRLALPGIGTVLEVPLLVARRLQPNLGVRSHQKQHHQHQQLHPQQGEDDRVGCGANVCNFSRGGNCGGGVAATSTSRSSEGAYANTRESIIKGKFERMCLFLIFLLSTRIQCENGNTILSKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Z0</accession>
    <name>A0A1D2N0Z0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vascular endothelial growth factor receptor kdr-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000310">
        <property type="protein sequence ID" value="ODM98939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0Z0"/>
    <dbReference type="OMA" id="KFQIARE"/>
    <dbReference type="OrthoDB" id="9864753at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="727" mass="82054" checksum="65E6E4C2B34E5E64" modified="2016-11-30" version="1">MNELGNFTELSKDIMQKYDPKMGFLLRAGSEPNVLAGKYVCSGSYKNDTEVVEVTVSPPKGFIVSPSKNHLTFRNSKISMQCKATEPVEMKFTNQNVPVQHHVREITYKSDTFKYGAAADIFTHPKQDQIRGDVSCVKKSNQEALWTWHYDTDYGCNCNWTLKNDGIKAARFYFLLDRTFRGTIRAYALNTEGDGYFLNIPTPRGELSCTSKASARVNMTFIPCENPVECQIKSGFLSWFDFDARSYSAESIFSDEDGEDNHNVTTISQGYIRSGIVKCGVGDYITTKFAIANLDTLYIDSVPTANLVRIVGPETNVFVGDKMLFTCMYEKFQIAREAQWAFMYKNGTIDFFDVEKKDDRFSYDLEKYLRSSFIKIPSSEITGLMCFAPVWNSTQWKNSTFALNVSPTPPVDAESPLNCPVDSNPIIILQRNSSISSRRLRVPHLVSNQTLSLYNPVDEIKLICRANYPVQWFRGTEKTNSSKIGKVPCNNVLSMKKVYEAVLHIDPLQKESTGNYTCRKTFAKYPQASAYIYAVGDGEATFVNEGRHMQVIKNVRDYDTWVTLPCEVSNPQSKPYLFLDHEDSERIHRLELGSNLRYDPKMGFEIDSSTVSDPVTTFVCSMSENATTFGVLITLHKQEGELIAGAIGSQQPPSGGMLLAFTIFLLALVILLAVGLFVMYRKCQEASTKPPDGHQMGTRDTFSSYDDVRIQHDDRENIVDGNYNRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1F5</accession>
    <name>A0A1D2N1F5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000298">
        <property type="protein sequence ID" value="ODM99126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1F5"/>
    <dbReference type="OrthoDB" id="8251699at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="351" mass="39358" checksum="58C51596A98FA14A" modified="2016-11-30" version="1">MRPIEAMPGKKTVTLYVVPQTALKLHTSSRRFKRANNLSLRFGISPAKYPEFVGLTDGYHIPAVEIPLRKPLVIRNVEVRVSAPEGFMVPYYGDNGYQAYPMSTGCLIAPIPPNTAISPDNPFEINRLFAVPSLPEYPTYRPAIEQHNHLHIHNGDDADLAETIAQYFPTPEPKPTYAVFELVPVTTEKSKKKKKEKKKKEKKESEEEEEEEEEKKEEKKEDKTTTTTTTEGTTTTTTTTTTTTTTTEATTTAAASSIQDIIASFSNRRFEQERVSNINNNNSNNRQSPVPVASSSPFRTNERSSSSDLASRETSYLAQLRQQSLRRQLDQLQKLLSSLNLGSSDRSSELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1K3</accession>
    <name>A0A1D2N1K3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CUB domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07588</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000300">
        <property type="protein sequence ID" value="ODM99091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1K3"/>
    <dbReference type="STRING" id="48709.A0A1D2N1K3"/>
    <dbReference type="OMA" id="SENNANC"/>
    <dbReference type="OrthoDB" id="8288656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904885" evidence="4">
        <location>
            <begin position="21"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="39"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="170"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="324"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="580" mass="64130" checksum="0E6A112D516AA018" modified="2016-11-30" version="1">MKMKLNSILISFATVTLALGAQNVPISINDAGQDQETRCGATIEADFGTLTVPSSGQAISPGSICIFMIHLQTTNIFRLNFSSLDVSSSSSSDEDCTEAAVRIYSLTNLIPPDKGESYTFCNDNPPPPSSGNFFLSGNLATVIYQNGGGNSSGFTLNFEGLAFQPIPIAHESTYSSATSGFIRYPPVGEYEPNKVTTWLVKTSSDTSNIQLDVAVQRMDIEECGSQLGQANECLCDTLILYDVTSTGVLKETTRLCGKSEEQLIFEGLGPNFILAFFTDHINLPMVGTGFDILYQPSAPVSEITESPTDTTELPPPVANYSNECGGILTGDQGLIEYKIGTDYNNYERCLWTVRTYYRAQIRFTLEESGIEPRFDNVQIYTINSDGVQDKHTFNSSEDLPKTIVLNGTVALVLFQSDYSTIGQGFSLRFIAEEVWDVNVWNFEDHHRVVDLANEEIIRFPETGYYKNLELSTLTFIRPKFNPLHMIEMSITSLELEVDTENGKCLDKLHIYEIRQPTTALPHEEHLFRHTDTDGICELAFVNSSSPPVLATGFVFILATNRHGTFDGFELKMKSPVSPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N258</accession>
    <name>A0A1D2N258_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Teneurin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000286">
        <property type="protein sequence ID" value="ODM99349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N258"/>
    <dbReference type="STRING" id="48709.A0A1D2N258"/>
    <dbReference type="OMA" id="VKDFYQP"/>
    <dbReference type="OrthoDB" id="188511at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46901">
        <property type="entry name" value="GH04942P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46901:SF2">
        <property type="entry name" value="GH04942P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="923"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="78"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="5">
        <location>
            <begin position="633"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1009"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1060"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1110" mass="122536" checksum="64CC8459AABEC893" modified="2016-11-30" version="1">MSAQHHQVKLPTNFTCEDCTVRLLRQATEWANNYRFWSCADVDIVPQKKYRETCGGHGRPVAGRCVCNKGFWGKRCEYEDECDGESECSNNGKCIDLGGTALPRKQCFCNPGFHGERCRKRNTVKLPLSSQSLDLSRHTKRELSDRLNLYYKIIPAAQEDKKEIEFVLEITGTSYGAIGWRPNGFNKTCQRWPFIQESEEVRNAKNAKIQHAGSEPQPEAEAEPKADSEPESHPESSAEDDHHKNHKNHKKEPHAEPEGEAEGESEPETAAEPTSSGGKHKKGKNISGHSHKGHHDDDHAHAEPESAAAEPESDAEPEGTAEPEGTAEPETAASDNVSSASKLKNKLREQKLPSGTDVRVETSSIAVVRSSKPRQKRSANPEDAKAEPEPEGEPESAAESEPTPEHSASDSDPKAEGEPEPEGEPHPEAEAEAEPGTEGSSKHATSGSSVNPRQELIPSEWAPKLNDFHAMDCIDLVMGAARGTLSRIRDYYTRDRSTPRLDTFWGGKEDITSATGWEQDGKTVLIFRRKIRSTDVADHDLLGDMHVIWARGQEPGEYNHSPKSGLERENPHRPNFYAADEIKYHGHGGQRGKTRIDFLNDQVTGRKKVVKGACEDSWSHPPGCSNQDAVKPCSYNATWQYIPEIDSVRFTIETRRADRWTGIGFSDDTFMRKSDAIIGWVQPSGQFFMMDTYMNSYNIPPLDARQDISNMTGKYSDGLVRLSFLRKVNTGDEKDLSLDECRFFLFPIQGGTYNAVNKKIGRHDETPVVSAQKVCIPRTCTPIRIKKPAEIRYAFDIKLTGGFGSSWTAPAKDTEDFNRLGNRIETDLSSKLKLIPGFGRIQLNEITKDGEQGAIAKLELMVTPDTELADSNRVERALKETIQDGKVGNLQLDPTYLQLQAPEVINDEEFEVTTASQFGGKRLWIVLGCVAALILLAIIQAILTIYKTSGKTSSHKGSPSSGSGMAWRDYSETNYGYDAYDEKTYGNAMPMTATSQMNYPANSGYHTYQAGNGNGYNHHPTTNMSLPRPQHQLHSQQQQHHHSTRNNGHGGASRAMEAGNGVGGGGSGGGERGGGGAGGASAANPDFYFMPSQRKYSGEVVRVYVDHNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2B1</accession>
    <name>A0A1D2N2B1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000283">
        <property type="protein sequence ID" value="ODM99412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2B1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904917" evidence="2">
        <location>
            <begin position="24"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="243" mass="25835" checksum="05409812746B191E" modified="2016-11-30" version="1">MKFQDFVCVALLSTLFLAAPTLCEDDEAVQANLTKSSGHINSPGLDRIKLSASGNQNASAKQSAGQGNPLTDSTSNTGGEPNAAKKSGNLSSIHDTESDETHFGDKRVESRSNASSSESGFVPSNHFLFVDHHAQGAAPPLSKRNSSADDFAHVEKHQLHQSLSDDSDDSFLAPPPVRKQSTHPKLGDSVIVSSDSVPVRIPPSTNTQVDNQGNPSIAIRRPIPLLRQQTAQKASVSNDSDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N307</accession>
    <name>A0A1D2N307_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein turtle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000265">
        <property type="protein sequence ID" value="ODM99649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N307"/>
    <dbReference type="STRING" id="48709.A0A1D2N307"/>
    <dbReference type="OrthoDB" id="6234674at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904954" evidence="1">
        <location>
            <begin position="18"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="16145" checksum="ACC08A35FCF89561" modified="2016-11-30" version="1">MVWLAGWLLVRLCDIFGGFWLDDDDNVALMARLVVDLKREDEQLLVSLSDAVVNPVTMTHLAQYTEVWWLETGVVEVGMGMIGVLGVPPPDAEYITAIIGESVVFNCHNCRVSDIYRVPYIVQWDKKEEEWEKEGRLPYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3N3</accession>
    <name>A0A1D2N3N3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000252">
        <property type="protein sequence ID" value="ODM99850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3N3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="98" mass="10743" checksum="A5C3C34177AC21DC" modified="2016-11-30" version="1" fragment="single">ALFFSPEKCSKYVLGGLGALILGLGCCSWLSVPTETEINPTNQGAQIEILFGILIKSAVLSYTMLCPLVYFQSYISEVDPRSITKDLQLTLDIYGFIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3X1</accession>
    <name>A0A1D2N3X1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Solute carrier family 35 member G1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06762</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000247">
        <property type="protein sequence ID" value="ODM99921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3X1"/>
    <dbReference type="STRING" id="48709.A0A1D2N3X1"/>
    <dbReference type="OMA" id="QIIFIRM"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="83"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="232"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="371" mass="40538" checksum="DDDDA8FD1427F8EA" modified="2016-11-30" version="1">MKYAKLEGENNGPCKEVIVFPAIGSASGKTGNNGSIQVADKGFQDAIYPQLINSARNVENANAKTPLLANKKKSIVPTKTNFFGIFLAFISGVFFTLCSGTVKYLTEVDPMELLIFRSLFQIGVTLPIALYKGQNILGPQGSRALLFAQGVVGGTTLVMLFYSFRLLPLGDAATIIFSSPVFVMIMSHIWLREPCGFYRTFIVFFLVTGVVFITKPPFLFTSPEEKETYNILGYVAALFGTIFTAINIVVMRKCKDVHFSVVVFQFSFWSLVISTCILLAGGTPAVPHQTATQWVLIVLVAVFGLSGQILVAIALAHEGAGRVAVTRSMDIVLIFNEVPDWKSIMGAFMVMICVIGMGIEDVVHRLLHKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Y9</accession>
    <name>A0A1D2N3Y9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cerebellar degeneration-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000240">
        <property type="protein sequence ID" value="ODM99996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Y9"/>
    <dbReference type="STRING" id="48709.A0A1D2N3Y9"/>
    <dbReference type="OrthoDB" id="10059415at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026079">
        <property type="entry name" value="CDR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19232">
        <property type="entry name" value="CENTROCORTIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19232:SF7">
        <property type="entry name" value="CENTROCORTIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="682"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="277"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="495"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="735"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="770"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="14"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="206"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="895" mass="99204" checksum="D32940F1F64C6C41" modified="2016-11-30" version="1">MSKRGSIQFSIRDLQLAAELGRTLLERNEELENELKQQQAIIEDQAQEIEFLTKQATSMKEQSEHRGKFYEQLEQTIIELERTNDHLSREHEVDKKRIQSLCENIEYLERKCEEMSRALETIRDEQTKRGFHGSRGKMNRGSYFNFGSDSSEEDNMNSGFGYGFGYGCRRRSHSLQDLRDYTPSPDEFDSGNSNSPDLKTSESEYVESLESRIEELLVAKKNEADKVNKLESQIRLLIQENANLQNQLVQMSNEKDEQIADLRRQLLDSDPSVAIISPASPSCSSSSTSSHSPRPSSSANLGDVEASSSSSSSTSSSSRGKTHLNHHGALDLLNINSNTMLMCKRCTAEVSILSLVNSIEVENDGEVNGCYADFPYGVTALAEDHDMEFSSLEHELARATGASLPLDNRHNKKSPPRNVNRSFPLFPRHRTSIFQRDKSANNKPHGNDIQLECDDDLEYDENFELFLGHQPTYPRGAEGSSPGKHGRRLFIMEESSDTCGSSTHDEDIDLDEEPCLTKDRKPEISRSKKNSGRLSSKNCSPKSKKVAGTSRNGGSSCGLYEEGSNVPVTNGELADDDDDDDNEGGAEGDEPAEELSITFTSRIHSKLLELPTRIPSDEEDDEDDYEYDDDVIDGILAAKHCVPASSDAAILQDHLRDGELLCENNNDQDKCQNREPVKKTKLWWLAWFILVVMGVFQLIWAILSLLFFLVTAAVLPGGSKGSSSFAAVSSSCGIQESSSSSGYDSSEEENEHGGRAGKAWLISTEVEKLPLVKEEEGEPEDKESVGPEVATTCPTDTDQKPEYDSHEDDTPEGGNLAITGSSISTPSTSCNNNSSVMPEYKQILQNLFSLFNNSKRKYPIPMYPYVKGQSSALIMSQSINSTSTNSNNNTGCSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N436</accession>
    <name>A0A1D2N436_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000237">
        <property type="protein sequence ID" value="ODN00034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N436"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904999" evidence="2">
        <location>
            <begin position="28"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="531" mass="58429" checksum="AFB5A8AF042E01AF" modified="2016-11-30" version="1">MIEFLMKIYLMTHRVFLGIVCLRMAEACKCKNSTKLHTRSINTNSQVTPKSTDCVELMLSLYCEKSKKLLMSSKRKSPPNKFEEAGERTQKGGGAEEQGVVGRAHSNQISANNKRVTPFVSPSSASEHHDDDEPQHPHHLHRHHQSPFEQDEDHEDQQEFSQQLSRRLHHSHSNQEEESLVSMDFQQESHQQQHANSVNRMVVEGGEGSSDESQDSQVVNLLKTRMDFRDNATSGGSVFPNHHHLPHHPPKSNNSSNSLITGSTKSSSRRSSHNRSSSHKPSHNNNNGPLSLSKSPIDDVPSDEDEHHHQGGSGGGGGEDFMMDDDGDEMMMDGLPSNSITANILRSQQHQKQQQQLLQQLRRTTRQSSHQVDRDGMEGSGDEDNDMSDLGSYCTPHGSDSEEIITSSANFHAKQPQHHQNLKAGNGNRRSSDNYGRRSSEYACSEQQKSPSSLSFSTGSTAAIHNNNNNNIDAKVHKKSMDDVLRKLTSKFGGAPGAGGTGNGANNGSVRSTGSSPNPHPSANLDNMEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4B1</accession>
    <name>A0A1D2N4B1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein Fer3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06571</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000233">
        <property type="protein sequence ID" value="ODN00118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4B1"/>
    <dbReference type="STRING" id="48709.A0A1D2N4B1"/>
    <dbReference type="OrthoDB" id="6375462at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11415">
        <property type="entry name" value="bHLH_TS_FERD3L_NATO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000035">
        <property type="entry name" value="Pancreas-specific transcription factor 1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050283">
        <property type="entry name" value="E-box_TF_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349:SF63">
        <property type="entry name" value="FER3-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="163"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="34562" checksum="5417BBC54EB0EAAA" modified="2016-11-30" version="1">MAKQQASKSNKQSAHNNSTISQSLFQMGQFYNHSDHLNHHSAAAAANAAAALAAAALIRSDNSNSVSALNAAVAATAAGISMWGGDTNPNQRNSASYYTPTSGGGHHSLHAHHHHHHGPDVIPDVMWGVRNTSAALPQTNSQQRSGPSNKPPKKPRRRVATMAQRRAANIRERRRMFNLNEAFDRLRRKVPTFAYEKRLSRIETLRLAIMYISFMKEIVMVPEGSEVNENNKGTPQGTPGLSHHGVNNQNSHYAGLSGGLGMVLGGNSVAAGAAGGNDAAMFPLSRLYGQQQGGGNMQPNVGYHHHHHHPHLPTSGGGVVGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5R8</accession>
    <name>A0A1D2N5R8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Plasminogen activator inhibitor 1 RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5R8"/>
    <dbReference type="STRING" id="48709.A0A1D2N5R8"/>
    <dbReference type="OrthoDB" id="6022699at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039764">
        <property type="entry name" value="HABP4/SERBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006861">
        <property type="entry name" value="HABP4_PAIRBP1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299:SF17">
        <property type="entry name" value="AT19571P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299">
        <property type="entry name" value="HYALURONIC ACID-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04774">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01233">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hyaluronan/mRNA-binding protein" evidence="2">
        <location>
            <begin position="165"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="319" mass="34802" checksum="CF902A2C6A30C53D" modified="2016-11-30" version="1" fragment="single">TGSTNVARKGIRETNQKGSSDAVKTGSRPNNAVEMKIMAKIIDDDDVCLCLVGNDAGNKPNRGPRNDRPPYDKDRGVKFTEEEREERNNRRNREDAGRELRTDSEFGARTGSRGGRGGGGGGFRGERRGGSRGGRGGPGGGGTGGPGGERGERGERGEGGRGGFRKREFDRQSGSDKSGVKPVDKRDGAGSRNWGTYKDDLEEISGGNQTAGEESAEDKPKDPEQVEDKEGENEKENQGDAANGPPGEEQPKLMTLDEWKALQQPRQKPVFNLRKPGEGEDLSQWNKMTLIKKEKEEEEEEEEEEEEVNPRATCNAKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N679</accession>
    <name>A0A1D2N679_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Gamma-aminobutyric acid receptor subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05914</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N679"/>
    <dbReference type="STRING" id="48709.A0A1D2N679"/>
    <dbReference type="OrthoDB" id="6422395at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="4">
        <location>
            <begin position="43"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="396" mass="44001" checksum="11C5E5D6EECBEB36" modified="2016-11-30" version="1" fragment="single">NPKFKLFFNNVRIHSSTKTDCFTVAFIFFLVQNSISNVAALDLPGNYSASARPNQDGVADVVNVSIELLSIRGVSETKSEMTVDIAMHTSWVDARLLEQVSRDTLFVGHIPTIWIPSVQIANSESGSHASSKALHLGKDGLVKYSKKMTTHISCPISLAKYPFDRQACRLQLNSFGYTTLHLVLVWHGTINDDVPTYHPEFSFSYAEQTSENIKTVDGEYSNLFLEVAVSRCPLRVIFRAMLPSVLLLAFSYYVTFCHCNLLRSKSTPSANGHHVEATVVAQPVIECTTPERSLIIVAINGIVLLVIVFVAQMNFIDSPKSSAVSGLDVWLNVITAMVFMILWHSVQLYFNEGNMSSDKMNPSEACYVNRTTNMLKIGIPVVFVVFFVVYCGVYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6B0</accession>
    <name>A0A1D2N6B0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Extracellular exo-alpha-(1-&gt;5)-L-arabinofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05905</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6B0"/>
    <dbReference type="STRING" id="48709.A0A1D2N6B0"/>
    <dbReference type="OMA" id="IDIWAPE"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905105" evidence="9">
        <location>
            <begin position="22"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="6">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN00762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="344" mass="38560" checksum="C6E137BF9E5EC3A1" modified="2016-11-30" version="1">MAAFKCIAVVLVLAIFGSAESFSLRNGTVKATFRNPVADFAWPDPYVHQHSDGFYYMPRSEENGVALYKSRTLSNWRNAERALVVRAPAGLMSLWAPEIHFINGNFYLYFALDNGDNANHRMYVSRARDAGNPMGGFTEPKRIVVPGDDFWAIDQTVLQYGNGQLYAIWSGWPTLNAGFPQNLYIARMCDPETICTPRALLAEPIYNWETNGAALLEGPQILHNAGRVFVIYSASGSWTADYNLGFMGIDNLADPMNPGNWWRHNQPVFWRNDEQSVFGVGHASFTRSPDGSEPWIIYHAMADPNAGWEGRTARVERFGWNPDNSPAFPRPSRLGTELEAPRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7X2</accession>
    <name>A0A1D2N7X2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pleckstrin y domain-containing family A member 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000157">
        <property type="protein sequence ID" value="ODN01354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7X2"/>
    <dbReference type="STRING" id="48709.A0A1D2N7X2"/>
    <dbReference type="OrthoDB" id="43122at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="22366" checksum="EE6502CD794BF7C2" modified="2016-11-30" version="1">MDPFEFFSVRRPVPVKASSNSTDLDFDENLIDRILGTPEKIDIPERYIPEEEPQLEPEEERKRSQKAEAICRLLSKSNGAGGLGIPLNPVRLPTTTPKANRLSFQDGLDPNGKGSCNSYPRERSYHNNQLYGSGKGVTSAASTAAAAQSTPASPVKRATSLRRPGSIISSSPAIGSGNSRHSYIHTSGSQSKCDWSLAGVCPPKEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7Z5</accession>
    <name>A0A1D2N7Z5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein Simiate</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000157">
        <property type="protein sequence ID" value="ODN01357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7Z5"/>
    <dbReference type="STRING" id="48709.A0A1D2N7Z5"/>
    <dbReference type="OrthoDB" id="532630at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032433">
        <property type="term" value="C:filopodium tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030027">
        <property type="term" value="C:lamellipodium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051489">
        <property type="term" value="P:regulation of filopodium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039169">
        <property type="entry name" value="Abitram"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13651">
        <property type="entry name" value="PROTEIN ABITRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13651:SF0">
        <property type="entry name" value="PROTEIN ABITRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="34103" checksum="2F007303AB49BA7F" modified="2016-11-30" version="1">MHPDLSSNLHTPECNKLIEALLQCHKENRFKRFLGVCNDANSIMLKCLKAERIQRRKENFDKSMEKRERLFGHPKPSSAMIKKLSFKRSWLTLTRIFFRIYTTVGDSSLTSSTISKMEDTQDIEDEYLSQGSAYETLTERSFGRFYFIEPNGGGHYRLLAHSNKICLITLAPSHPIITNDLVVSTINYQANDNCNRMNNKVSGKRKAGAQFLTDCSILCSIKCEGREEPFIVRSNLVAKLIEMNKDISETPNLLKNCEKGYIAIVFPKLHEFDREIRRWMTEEEYLLKIKSDNVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8T6</accession>
    <name>A0A1D2N8T6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ras-like GTP-binding protein Rho1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05015</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000144">
        <property type="protein sequence ID" value="ODN01669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8T6"/>
    <dbReference type="STRING" id="48709.A0A1D2N8T6"/>
    <dbReference type="OMA" id="EERPQMA"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032154">
        <property type="term" value="C:cleavage furrow"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000915">
        <property type="term" value="P:actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000095">
        <property type="entry name" value="Rho-related GTP-binding protein RhoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="194" mass="21613" checksum="CF1951E38E85E604" modified="2016-11-30" version="1">MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVTCGASTLDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWNPEVKHFCPNVPIILVGNKKDLRNDPATIRELAKMKQEPVKPEEGRAMAEKINAFAYLECSAKSKEGVREVFETATRAALQVKKKKRGKCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9B5</accession>
    <name>A0A1D2N9B5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pancreatic triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04837</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000137">
        <property type="protein sequence ID" value="ODN01834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9B5"/>
    <dbReference type="STRING" id="48709.A0A1D2N9B5"/>
    <dbReference type="ESTHER" id="orcci-a0a1d2n9b5">
        <property type="family name" value="Pancreatic_lipase"/>
    </dbReference>
    <dbReference type="OMA" id="KSFRRCK"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00707">
        <property type="entry name" value="Pancreat_lipase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033906">
        <property type="entry name" value="Lipase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002331">
        <property type="entry name" value="Lipase_panc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF173">
        <property type="entry name" value="LIPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00823">
        <property type="entry name" value="PANCLIPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00821">
        <property type="entry name" value="TAGLIPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905247" evidence="6">
        <location>
            <begin position="18"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="496" mass="54069" checksum="DF407BE977F164B7" modified="2016-11-30" version="1">MKTAVAFIACLIGVALGASVIKDGREPDNMREICFDKYGCFSTDAPWTSLIRPLGALPKPPHEVGTRFLLFTRGAESEGYELMPDKDAILRFSDFQATRKTYFLIHGFTDSHKADWIWSTKNLLLQNEDVNIISVDWAPGAKAPYLQATANARLAGAQIARMITYLEQKGDLNIDDVHVISHSLGGHVAGYAGDRLLGRLPRITAIDPMDPYFGGTDPIVRLDTNDAKFIEVIHSNSDSASNLGLGIPGAIGHVDIYPNGGKKQPGCHDTLGNLIISIIDLITLNFDGAISTWACSHARAAHFYAESISDTSSCPFVSYACADYSTFQKGSCYHACGEREKCTALGYNAKNHPASGVYYLHTTDGANNHTYCKQMVQLQLPVSITQAQTQGSLTLVFRGHDGTLSETFSLADNVRISPGQILNLWVEVPNYILRTPDEKTSLILRYTRGGLIPGNQAKTLALDEVDLVVIKPDLTTLTTSYQGVTLNYGTDTQISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9M5</accession>
    <name>A0A1D2N9M5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transformation/transcription domain-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000132">
        <property type="protein sequence ID" value="ODN01959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9M5"/>
    <dbReference type="STRING" id="48709.A0A1D2N9M5"/>
    <dbReference type="OrthoDB" id="5570127at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="32545" checksum="78086EEAFCDD75E6" modified="2016-11-30" version="1">MDIADPTSLPTTRNQAKRDCQAEHEVYGPKTRRGFPPTSSGRRLSSWELSLLEMFELVCSKLGFEADSLGKGEILTHGALRDIFQGIQQGLVYVDVLKNWAAQNYVSVSDYLYFTTEMCLNILAEYAFQLTSLQPEGLNIHSDTGLVNISYFKFDTDACQLTVPFTLTSNLYEFMTENGVNGPLTFGLKALAKCLAHPNYKLEAILRPILKDEMLANVKRNEGENCLGWETPMETYDPETVTDLVNNAVSAIMNRLSGITGDVDVGKVNELIAAASSVDNLYRMDPSSYHWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA14</accession>
    <name>A0A1D2NA14_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_04581</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA14"/>
    <dbReference type="STRING" id="48709.A0A1D2NA14"/>
    <dbReference type="OMA" id="STMPKFE"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="78"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="318"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="469"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="518" mass="58355" checksum="360FBC6133F18306" modified="2016-11-30" version="1">MERLQPFEKNFYAPSPAICNRSQHDVDAFLHKNQITMKGRDIPMPVMHFQEASFPEAVSGTIRKAGFENPTSIQAIGWPIALSGRDMVGIAQTGSGKTLAYTLPAIVHIGHQPRLERGDGPIALILAPTRELAQQIQQVANEFGQPSRVRNTCVFGGAPKGGQARDLERGVEIVIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQVRPDRQTLMWSATWPKEVRVLAEDFLKDYVQINVGSLTLSANHNILQIIDVCQEHEKENKMQRLLEEIMAERETKTIIFAETKRKVDELTRVMRRYGLRMLLDEIGTEQDNKTIVFVETKRKVDEITREMRKTGWPAMCIHGDKSQNERDWVLQEFRSGRAPILVATDVAARGLDVDDVKFVINYDYPNGTEDYVHRIGRTGRSSKTGTAYTFFTHGNAKQAKELVDVLREANQVINPKLYEMMESSRNLGGRGMNRSRWRTPGQPLGGNRGASGSGYNQNRGGGGSRGNYGGYDYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAD8</accession>
    <name>A0A1D2NAD8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04468</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAD8"/>
    <dbReference type="STRING" id="48709.A0A1D2NAD8"/>
    <dbReference type="OrthoDB" id="10062378at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005918">
        <property type="term" value="C:septate junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035151">
        <property type="term" value="P:regulation of tube size, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019991">
        <property type="term" value="P:septate junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004031">
        <property type="entry name" value="PMP22/EMP/MP20/Claudin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284">
        <property type="entry name" value="EG:80H7.2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284:SF11">
        <property type="entry name" value="KUNE-KUNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13903">
        <property type="entry name" value="Claudin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="166" mass="18576" checksum="0AEB34865AC4C20D" modified="2016-11-30" version="1">MNISNKIVHHMEPGTSASTASAPPSTITTKSMSVFVWNSGDMAADSTSIPGHIKISFACIGVAFLFIIIAFSTSYWLATDGDLENPKFIRIGLWEGCFNNLHDANHNFDITITGCRYLLSEELYHLNDLIFQLWCCHKILIVENCKCKLNDEMSIFDGFNIYEVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAY4</accession>
    <name>A0A1D2NAY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Interferon-inducible double-stranded RNA-dependent protein kinase activator A B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAY4"/>
    <dbReference type="STRING" id="48709.A0A1D2NAY4"/>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016442">
        <property type="term" value="C:RISC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070578">
        <property type="term" value="C:RISC-loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035197">
        <property type="term" value="F:siRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070920">
        <property type="term" value="P:regulation of regulatory ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051247">
        <property type="entry name" value="RLC_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46205">
        <property type="entry name" value="LOQUACIOUS, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46205:SF3">
        <property type="entry name" value="LOQUACIOUS, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRBM" evidence="4">
        <location>
            <begin position="135"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="358" mass="40002" checksum="95C70664EA2DE0A1" modified="2016-11-30" version="1">MTELFGKSPKMWVNELCAQQGALIHWQTLARRDAFESTCTVSYTDGDVVAKGQGQRKILAEQNAAADILFSGMEFTKPKIYALNQNKRVPNVASLFSNGTVPVRFTNGNGNNNMNEPGSDTDADKRDDNEALGTNPVGALQEAFAKMSVHPEYKELEKDGPDHEPYFTIQCSVGQLHETARRSTKKQAKAIAAHRALKKLKANQFNLTLFETNESNADDVTDENGTEDSIESLIGNLNLNGSLANSSCTLKSEFTSRFGEKFQFLEDNDILTSGAYTDKKYEILLDSICRQSGIILTVYEPFKWEERDHYVVLKMKYPFENYSPYFSVVEGKGEDKCEAIQKCALEALSLLYTKFIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC96</accession>
    <name>A0A1D2NC96_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein Smaug 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMAUG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC96"/>
    <dbReference type="STRING" id="48709.A0A1D2NC96"/>
    <dbReference type="OMA" id="LAITDEW"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030371">
        <property type="term" value="F:translation repressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.170">
        <property type="entry name" value="Smaug, PHAT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037093">
        <property type="entry name" value="PHAT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAM" evidence="6">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="16289" checksum="D3359F5F2004EF6D" modified="2016-11-30" version="1">MDKIDFILFSEVPTWLKSLRLHKYAFLFAHLTFEEMLTLSEEGLEQQGVTKGARHKIVLSIGKLRERVSQLKQLSDQMTRDKDSLRTALTELKWMLTTPIKPPFATESEDGGTSSSKERESSGSGSGTGGSPSGGVGRLEAIDPSLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC98</accession>
    <name>A0A1D2NC98_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000103">
        <property type="protein sequence ID" value="ODN02626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC98"/>
    <dbReference type="STRING" id="48709.A0A1D2NC98"/>
    <dbReference type="OrthoDB" id="2017974at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09885">
        <property type="entry name" value="PIN_Smg6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF0">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN EST1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN" evidence="3">
        <location>
            <begin position="732"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="919" mass="105782" checksum="A594449E1EF287F8" modified="2016-11-30" version="1">MGGGLLETSRRGKESMESHGRSSGSDLKSSTTSYLYAKRDGSDDDTEEEWVKCKVAQQFPAANLRMPTGTGTAHWVKYFAKLEEPLREWYNQRNSPDATRLTTANWNLILPYAERLMAVGFKLFINDVPKYLKNELDIRVWKYGIYLFIHVLRGRVPSDEKQKKAVRLVYEDVLSRGINHFKGILMQSTKVLGINLGPILFRRGFIRGSLREAELTSEENLVYRLLIALGDLYRYAFEVMKRPSDLKMAVDMYNAARLVDTDKCRAYNQLAVLSKSQNYLIETIYYYTRAWAGSITAEGSRDQLLYLYDDIYKKYAATKAGFWSSVSKTVEAELKVPRLNRKELWLSPFRQDKTLPPAFKCSLNKQHHIESLTECEVLARFSLAYAHLMGILYTKIGTENLEEVAKNAMIYFEGLVFQKKSIKFAHLMKVIGMLLFMADHLNRCMPGQSPGTVSQLDFMRDIAMRVTIEMVGYMSECIIKIFKLLDWDNPTLTTYLAAVHVWIRWAKGRAYVFSEHLKYWRMTSPRNIAEKTKLLLNENTAASFRRLVNEIRLLSNYSKYIFPSISFGATENCDTRIPTLPEQLLLDRFGTILLPRDYDMSSYFSNGRHGPERAQNQLRLSRIVKFGKRLFGDPKVPPKSPREDSDDLLSEPEDKSIADQNVLSLIQRFLKPTPKNFKVGKPDCNNARVIVRKSSNEKNQCLLPKHSTTKVYELWSNLCAMGVRTDMLIQPLRVVLDTNCFIRNLEWVECLLKVYPGTLYLPTTVISELRGLGKGLKPSRSRCKPLSLQQNKTRMIDSLVVAGQCSSALAFMKDQLHRFTVVTTKGKTLKMYNIMKQKIFDSMLDGVNNDEKILETCRQLEAQDEVTRRKDTPFRIYRNTVLLTADRSLRLRAYASDIPAREVHNFTLWLIQTPNGKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCD6</accession>
    <name>A0A1D2NCD6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Programmed cell death protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000092">
        <property type="protein sequence ID" value="ODN02924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCD6"/>
    <dbReference type="STRING" id="48709.A0A1D2NCD6"/>
    <dbReference type="OMA" id="NDAVGFE"/>
    <dbReference type="OrthoDB" id="6017654at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090443">
        <property type="term" value="C:FAR/SIN/STRIPAK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903358">
        <property type="term" value="P:regulation of Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009652">
        <property type="entry name" value="PDCD10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053750">
        <property type="entry name" value="PDCD10_Homolog"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13250:SF1">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13250">
        <property type="entry name" value="TF-1 CELL APOPTOSIS RELATED PROTEIN-15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06840">
        <property type="entry name" value="PDC10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="128" mass="14875" checksum="1F0D239144E85D61" modified="2016-11-30" version="1">MTSEYRTSRGEEPFRELSKKSAQLKRILSRIPDEIIDRKTFLETIKEIASTIKKVLDAVAAVSALVPNPNARALLEQRKREFVKYSKRFSTTLKEYFRDGLENPVYLSALYLINQTNLIMMTVKDRCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDU2</accession>
    <name>A0A1D2NDU2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA replication complex GINS protein PSF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03261</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.</text>
    </comment>
    <comment type="function">
        <text evidence="6">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS3/PSF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000074">
        <property type="protein sequence ID" value="ODN03421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDU2"/>
    <dbReference type="STRING" id="48709.A0A1D2NDU2"/>
    <dbReference type="OMA" id="YQSALQM"/>
    <dbReference type="OrthoDB" id="10251744at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="47"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="17599" checksum="E32B0EC196BB4331" modified="2016-11-30" version="1">MRFLDPSQASTDLPAGSEIELPIWAARVLSKQKRAFISIKMPKFYGEGYREVLKADPTVVDLNKMGPQYYQSALQMCTLPSAEMEKISDSLPDILQKRVIAMADSYSLHRDVKSTDEVSNQMGNMLKFHHMDPLELQIFNDSKAASEDLDDWLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEN1</accession>
    <name>A0A1D2NEN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEN1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="54" mass="5994" checksum="FE3F31931063AF87" modified="2016-11-30" version="1">MFRPLPSAEDSADSDGEELQKMKQMMSYHVVSFGLIVGLLRLAKTVAENMGYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEW3</accession>
    <name>A0A1D2NEW3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02913</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the WD repeat peroxin-7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000064">
        <property type="protein sequence ID" value="ODN03772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEW3"/>
    <dbReference type="STRING" id="48709.A0A1D2NEW3"/>
    <dbReference type="OMA" id="FAVHWNL"/>
    <dbReference type="OrthoDB" id="273771at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005053">
        <property type="term" value="F:peroxisome matrix targeting signal-2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044536">
        <property type="entry name" value="PEX7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027:SF1">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="36907" checksum="FDEEFF94E4721C17" modified="2016-11-30" version="1">MASPPFPQAPSPTVINTDPGHGQAVKFSPFSGHRFACATGSDYGLSGAGYLFIMERNEATGQVAPKLRLDYKDNFLDVCWSETDPNIFAGASGDGYIQVWNLGNKFPKVPIHEFKGHKREMSSVEWCLAKFGNTMLASSWDGTVCTYDMTSQWPVVKIPVSDLIVYQSVWSPHAPGNFITASADGVLQLWDLNVNNLKPQIYLSASDNELLTCDWAKYTPTLVITAGADSTIRGWDLRNYKSPIFQIDDHGHAVKKAKFSPYSPTVIASTGYDMSLRIFDYHISDINIEILNLHSEFVYSLDWNMQVRNEIVTCSWDKTVQLTIPNCLKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFW8</accession>
    <name>A0A1D2NFW8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02703</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFW8"/>
    <dbReference type="STRING" id="48709.A0A1D2NFW8"/>
    <dbReference type="OMA" id="EGYNWGQ"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="158"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="353" mass="39433" checksum="3D6E5954DD0E207E" modified="2016-11-30" version="1">MESSGSAPAAGTGGTGNNNNPGATVGSGTTAAPVTDLKPMNNGTSVSGISVKELDQWIEQLNECKQLTESQVKTLCEKAKEILTNESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDSQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHSNGITLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDQLKYSFLQFDPAPRRGEPHVTRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGF5</accession>
    <name>A0A1D2NGF5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding protein D-ETS-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02529</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ETS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000052">
        <property type="protein sequence ID" value="ODN04185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGF5"/>
    <dbReference type="STRING" id="48709.A0A1D2NGF5"/>
    <dbReference type="OMA" id="NYITWEG"/>
    <dbReference type="OrthoDB" id="10067219at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000343">
        <property type="entry name" value="Ets at 65A, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046328">
        <property type="entry name" value="ETS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849:SF304">
        <property type="entry name" value="DNA-BINDING PROTEIN D-ETS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00178">
        <property type="entry name" value="Ets"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00454">
        <property type="entry name" value="ETSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00413">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00345">
        <property type="entry name" value="ETS_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00346">
        <property type="entry name" value="ETS_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905524" evidence="6">
        <location>
            <begin position="23"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="ETS" evidence="7">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="166" mass="18716" checksum="9E0172CD9EF3477A" modified="2016-11-30" version="1">MGSGQIQLWQFLLELLSDSSNANCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGLAAATQPAATDPTAYKYQSDFFTMSSYHAGSIFPSHSSYWGTPSANLYSNIAAASGHSMAPHASHMTSHLSSYPHYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH20</accession>
    <name>A0A1D2NH20_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Extracellular exo-alpha-(1-&gt;5)-L-arabinofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH20"/>
    <dbReference type="STRING" id="48709.A0A1D2NH20"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18820">
        <property type="entry name" value="GH43_LbAraf43-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43817:SF1">
        <property type="entry name" value="HYDROLASE, FAMILY 43, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="521"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="6">
        <location>
            <position position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="921" mass="104688" checksum="C4699294FBB608A2" modified="2016-11-30" version="1">MRVALGFLKMNRFLVSIGMLCMLIGISNCQLSFTNPILDRNSADPAVFRVGDSYYLTLSENRETELTIFKSPILTNFRNAEPKVAYRTPDGYSDLWASEMHEVDGQLYIYFTMRTTDRDHRMYVIKADDPANPMGNWGNPTRLLPDWDFWAIDGTVMKHGNRNYFLWSSTRTGPLSIWIAPLDTPTQVGSPAVLLRQPSQDWECQGGCVNEGPYFIYNRDVSYMIFSASSTWDPGYCLTQMSIPFNRDPMVPENWDSLNGPVFTRNDEEGVYTTGHAAFTVSPDGTETWMVYHGTTSTTQIDGYRIARVEKIDWNEDGSPRFPRAHGYNNPQPVPSGQTSLTFTNPILDRNSADPCILRLGDFYYLTLSENTETELTIFKSPILTNFRNAESSVAYRTPDGYSDLWASEMHEVDGELYIYFTMRTVEKDHRMYVIKADNASDPMGNWSEAVRLLPDWDFGSIDGTVMKHGGQNYFVWASTRVQFLSIYLAPLVNATLVARPIVLLRQPKEDWECQGGCTNEGPFFIYNRNVSYMIFSASSTWDPGYCLTQMSIPYDKDPMIPQNWDSLNGPVFSRNDNEDVYTTGHAAFTVSPDLTETWMVYHGTVNTTHINGFRTARIEKIEWNEDGSPKFPVAHGYNNPQPVPKIGSSLTSPISSQNHIFTMFRSAFIVLVSTLAIVRSQTFRNPIFDRNSADPCAFRLADHYYLSLSENRETELTIFKSPILTSFRDVEKKIAYTTPEGYSDLWASEMHEVDGELYLYFTMGSVHFDLHRMFVIKADNASDPMGNWSDAIRLLPDWDYDAIDGTVMKHDGKNYFVWASGRTGHLSIYIAPFVNATLVGRPIVLLREPKEDWECEGGCTNEDGTETWMVYHGTVNTTHINGFRTARIEKIEWNEDGSPKFPLAHGYNTDQPVPSGQTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHL1</accession>
    <name>A0A1D2NHL1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein FEV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01937</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ETS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHL1"/>
    <dbReference type="STRING" id="48709.A0A1D2NHL1"/>
    <dbReference type="OrthoDB" id="10067219at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000039">
        <property type="entry name" value="Friend leukemia integration 1 transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046328">
        <property type="entry name" value="ETS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849:SF304">
        <property type="entry name" value="DNA-BINDING PROTEIN D-ETS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00178">
        <property type="entry name" value="Ets"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00454">
        <property type="entry name" value="ETSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00413">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00345">
        <property type="entry name" value="ETS_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00346">
        <property type="entry name" value="ETS_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETS" evidence="6">
        <location>
            <begin position="77"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="25341" checksum="FF39FF05E64BD738" modified="2016-11-30" version="1">MKTNNFQDAWSYSHHHISYPAPRLSYGGSQKDFNGGVPPPPPQDFRYYEPPQRLILHQVAAAAAAAAIKLVKRGRQIQLWQFLLELLADASNKCITWVNDGAYGEFKLVDPDEVARRWGERKGKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYKFDFNAIFMHQSNNNGSFYHAAAEIEQQARDASNIHHYNGSTQIITQNNNYFYCNSRVCEHARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI20</accession>
    <name>A0A1D2NI20_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cathepsin L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01893</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI20"/>
    <dbReference type="STRING" id="48709.A0A1D2NI20"/>
    <dbReference type="OMA" id="ASNWAYY"/>
    <dbReference type="OrthoDB" id="10253408at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000006">
        <property type="entry name" value="Cathepsin S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012836831" evidence="7">
        <location>
            <begin position="16"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="9">
        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="8">
        <location>
            <begin position="114"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="330" mass="37148" checksum="FE9BBDCFCDB9E40D" modified="2016-11-30" version="1">MKCFVLLVVVAFAHSLSVTELLKDEWDAFKSHHSKNYTNDVEDRFRMKIYLENRQRIAKHNKNQDNEYKLRMNKYGDLLPHEFKSIMNGYRLDLKRNSSEHERIVFLSPENFDAPKSVDWRTKGYVTPVKDQGQCGSCWSFSATGALGRQHMRKSGKLISLSEQNLVDCSGSEGNEGCNGGLMDNAFRYIQKNKGLDTEKSYPYEAQDDQCRFKASDVGADDKGFVDVPEGNEKALKKAVAANGPISVAIDASHETFQFYESGVYFEKKCSSTELDHGVLVVGYGTEDGKDYWIVKNSWGEGWGDGGYIKMARNKNNACGIASQASYPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIX0</accession>
    <name>A0A1D2NIX0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein 94</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000028">
        <property type="protein sequence ID" value="ODN05210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NIX0"/>
    <dbReference type="OMA" id="GCAMQTP"/>
    <dbReference type="OrthoDB" id="5568754at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039720">
        <property type="entry name" value="TMEM94"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13219">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13219:SF6">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1152"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1182"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1225"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1317"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1347"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1380"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="823"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="905"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1432" mass="162538" checksum="1E24E00B3685438C" modified="2016-11-30" version="1">METNKEKIIGLSTEEAFDRLFQELGTKLSSYRSTVGSNWLEIILSSISTRSHHAIITWTSLLILLVESIIVFSLYSINYSQMWTKLLPEAITLLFLLIFNILLLLFDNYKRVNELPVKLNLILSQLKDISSEVSWTEKNYPDLCMPISPCITLQWCFRDGKLVNLPWALLVPGDVVVLQPSQKIVAECCLLEEPSMKFSIGQIYSPLSSAQTAGSPPPRLHNAFPKSLAVVTTAPYIDMVDLSLKHFLRRPPTFYNKERHTIVTRIIECIVLPLGIMSFVALCLVRMFYLPHWLAIRVAPWADIILLQPMTNTFPLIPVSLPLLWILLNCVGNAKLWEMLEVWDDSATQHSPSEGTGGMEEKVVLNKRKQQCRDNVKLWQRMREFMFDREETLHRSQKLLHVLASVTALCCVDKKGILSWPNPTPDKIFFLRSVPTGSNLITPDSESPQPKDYPGGLKKNRRSSTVSFPSTTTVAEVLDITIDNNNELHFDETNWEQYLPNLKPLGLNILLNTCNDKTRRVYANFYSHISHELRYKKADNRLDLVVPVTSRRCLCDVAHMIGFGDKATDVFDLEQPLCSFRHIESDQTSRDKLTKAKIKFPFPHMMSVIVREKASGSLQLMAQGTGDLILDTCEDFWDGKDLKPLTDYERKLIIDFYQRMSLSSTCTAFSYKPVTAKVNQTMSDSYMELPPSKGLRFLPYYAFGNISDFINERESEKCAFVAGKDSSISTDCLLTDSNKNIEVSDLLGCLQVQTGQIFIGMVTMQYQACMDMVQLIEQLDQACIRFVHFSKENELRSRLFSEKMGLESGWNCHISLSSAVEESSEATDNYDESNEGSYSNGNPSNEESRRLIKGSTTSAHKCKSNRLCQTRSACRRTSTSGLPSEDSLLLPRCSSSVPEMVMLSTKIKEESEIPESTEPSQGEKHKEKSPSDDIQSIGFGFSSDEEEHSQLSRVRFEDPIKRNFLSLDVQNTERSPCSSAVMSPNNTDSFQEVYELVEHPTPLGIDMSNRAKLPIGIEQVRPHLENVDNVPLLVSLFTDCTADNTREMIHIMQDYGEVTLLLGSVCNADNKTVFLQADASISVEPMFPQSCQKTPAFSNPSGGVPAPSDVAMLLTSLPSSLTFRRRDYISFYDLVAQARHFMNRCIRNSMQYWLCCNIAVTVLGLFTLLMLLPPLFALGDAIWLSCAIIPVLTLGLAFSIMEKVDYNVMDNASWKNQCQVDRQMFIYAFWFYGMKFLPSILNVVFMASFNLVYICQNLPNATCAWVYPVSANPVPPIQNAEQTKFSKEAESISVLKTNCISTWSCENADRLLFVQQFSLFFLVLYFVTISAGFVYRSKYIWVLNPLGNKIWVITSIFVLISQFMYGFLKVSFSKSIDYTLLPIFSYIWGFLWSPILLAFNEILRRQEIKSNIRYEKRARLDFGTKLGMNSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ19</accession>
    <name>A0A1D2NJ19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tyrosine-protein kinase transmembrane receptor ROR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000028">
        <property type="protein sequence ID" value="ODN05219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ19"/>
    <dbReference type="OMA" id="AYITCIV"/>
    <dbReference type="OrthoDB" id="6377396at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF6">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 7, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="101"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="33605" checksum="A2EA47E0B5261D2C" modified="2016-11-30" version="1">MDGGGDGRPVVSWIRKKDLHILTSGSHIYTSDPRVSLLREGKLLNSWTLKLSSVQKKDLGQYECQVNTEPKMTITLYLIVLGSTDDEVQQGALALGMLDLPQHQRDSSLDTFSKGYEARILGPGHVQIHQGQTANLTCLVAHGGPSPNITWFLNDIPLLKTSNTRGGINIETERSPFATISKLVIVRADRRDEGKYSCGGITVYPDSVVLRVLPFHSRSEEESDEAVPMMVSVASSARVGAKPPFSSIHLDPSTIIITNRHHSFNKLLPTWTHFARQTTSIFFASFITYIFHYQAIHSLNAPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJB8</accession>
    <name>A0A1D2NJB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein kinase C zeta type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01323</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000024">
        <property type="protein sequence ID" value="ODN05373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJB8"/>
    <dbReference type="STRING" id="48709.A0A1D2NJB8"/>
    <dbReference type="OMA" id="ECMENRI"/>
    <dbReference type="OrthoDB" id="9976063at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20831">
        <property type="entry name" value="C1_dGM13116p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039934">
        <property type="entry name" value="C2CD2/C2CD2L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21119">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21119:SF5">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="4">
        <location>
            <begin position="119"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="20185" checksum="11410435B6D576AE" modified="2016-11-30" version="1" fragment="single">TRSHSVVTTETRSADGEEEKDTVSDKDDIFKRSVSADRHSLLSQQGRLNIGGGLGSARSSVSELSAISGHSTTTYVHENSTLVIECMENRIRKYYLVPPHLAETGKWKKRGKKLHIYNDHTFVAKHISSGKICEICTVRLPFALGKQGYQCRDCKMICHKECHVRAPSYCPKTSVYDIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJK2</accession>
    <name>A0A1D2NJK2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJK2"/>
    <dbReference type="OMA" id="VENVETC"/>
    <dbReference type="OrthoDB" id="10644202at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="6"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="636" mass="71983" checksum="824CBE6DBBC88595" modified="2016-11-30" version="1">MQANSVTIDNAIPDEVLGKIFRQCPYESLGALRTVSKRWNRVVDTFTGRMLIVKTGNEYQVDSESTLDKLNIKANYWMTLPRERTRSNESLSISNSSTSNEPTNVENVETCLPEISHGKHVHKVGLVGDITLKSMEYFLHQCNNVTSLYLHLSLFNDKEFEDTEKTFSISSLIPFLKELVIDSSGMNTGNSPPTHFSYKRAFNSVFAFLDNNKFSSLNKFIFGLPYFESREGIVVQKLANFLSKHSETLKSFSLHQKYDVQSEKSDSGSEKGTVDKSNRPESGEGDCRGESISPSSSKCSNSDYLSLKYLAVNALELKKCSLEEIHIVLLKTQESSPLWKNLLLHQERMKRVIFAGDKMPCPVSSIECNWATLVTLRLDLRDGVNLACFKKCIHLKNLTLGGRAEAYYEDEFDSDEEENQFDQTLQLRNVNCLPKSLESLEIMNLRTHQDDASIICMELPELRDLHLKNLGWEGNLGLRLGDLVQMWIMGRLDHFCIEASLNMMSYSEIEKSRSVPPELNLMACVLLSNSFTAVSKFYLNVWKNEAGMYTTVETKNIASEITDVFQIPDNVVMKDEEETDDESESEEEEDSEEENSEEEEGSGNEEEGSDDDYEDAEQSESDLDGKEVKAKGGKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJS7</accession>
    <name>A0A1D2NJS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer dense fiber protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJS7"/>
    <dbReference type="OrthoDB" id="429991at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="189" mass="21242" checksum="BE4539CD351B7A45" modified="2016-11-30" version="1">MKGKESDPSPIEWGNKPAEAKIKVLPRAPCPIIHGNHDTLKGKFKMPGPNKYFIEECPCIEPGVSFKGRYKEKIGVTPGPADYTPKYVYEQPPTAVIQGRHKEKAKKVFDPGFITMKPDKIVGGLMTPRWREREEEVEGPEMTNTFGMTNRGNARSAIPISFKSRHTPFKYSHMAEPRSMEYSGTTGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJX3</accession>
    <name>A0A1D2NJX3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJX3"/>
    <dbReference type="STRING" id="48709.A0A1D2NJX3"/>
    <dbReference type="OrthoDB" id="7932469at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="2">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="436" mass="48051" checksum="25CA02135BCDE515" modified="2016-11-30" version="1">MTSSSNGTLSRRNSCGQQEKPPPPRRNSSISSSARSSPVPTNSSSNIYSSGQGCTMTQSQSSMNNSEYQTIQRNSNSSHPLQPIFIKNPQYSYVSSNNSVVSSQGSFDSGETTPHASMESLPPPPAYLINEQNATTILTATAEDLSKRLSVADTVRTLTEKNHQPLSPNMVRRANSMKQPGEEIRESRSQSQTNGRRGSASTLESSKQRANLMQVLNQKLAQHQTPPPYSSGYPPIPNQKPIQPIYHQTASPHHPPTSAHHPPQPIYSQVYQPQPIYQQVNTGNGSAGNNNAASRHPRRLSEELLKTTATFVQNRVLGSKTPPPIVTSKEIFVQTLNAKLSQMRPSPNEKKVSTMQHPQMQMQSSNGRASGYSSKHAPSKPSREEISRAIRVRKWISSKTVSDPAVCRDSLMDQIRRGTKLRTTRAMNDRSAPRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKV9</accession>
    <name>A0A1D2NKV9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase</fullName>
            <ecNumber evidence="5">3.5.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Peptide:N-glycanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_00860</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue.</text>
            <dbReference type="EC" id="3.5.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.52" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000015">
        <property type="protein sequence ID" value="ODN05849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKV9"/>
    <dbReference type="STRING" id="48709.A0A1D2NKV9"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1020">
        <property type="entry name" value="Peptide N glycanase, PAW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010876">
        <property type="entry name" value="C1orf43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038680">
        <property type="entry name" value="PAW_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006588">
        <property type="entry name" value="Peptide_N_glycanase_PAW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF19">
        <property type="entry name" value="PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07406">
        <property type="entry name" value="NICE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04721">
        <property type="entry name" value="PAW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51398">
        <property type="entry name" value="PAW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="588"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="PAW" evidence="15">
        <location>
            <begin position="313"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="772"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN05849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="842" mass="95935" checksum="364E1810D1EEAEB9" modified="2016-11-30" version="1">MAASIPFQLSSNESAFERQLLSYIQQFKRYEDKSNQLQALATVPLEDLRAIAQAKYDSSEKPLGASFSQISPSSVVKDILLLELMDWFKNEFFTWMNSPSCPRCKQSTKGIGSGVPTPTELASSASRVEIYTCTSCFSDNREVARFPRYNDPTVLLKTRTGRCGEWANCFALICRAAGFEVRHVHDHTDHVWVEVFSSGMMPNRWVHADPCENSYDNPLLYEVGWGKKLTYIIAVSQDDIQDVTPRYSKDFTKLLPRRNQVRETWLVSAIVKIRKQLQVSLTESRRAELLQRWIQEIVELVTPKQSNDIKESEKIGRESGSLAWRLARQETDGPSVVPPSQEFTWKIGEDSVVDGTFQLLYDSELDAYAVKNGTIAKRGWRNGVFSSSDVFRKEERDWKMVYLAPQENSKPRNSKICWKFTLDPGFSIEDVNISIKYSIFQSDARFRLEFSTEQLEMKTLLETNAGDRVFAWNSKSSTDSDWHSKLEKSKTFSVACELISGSGNDGWQKVQLFRQKITGANSLLTQNSIFKIECKVDPLDLVASKRALKLSIQQVGKIQGMLCNKGLMTLQLQEDKSEQWIRKMAGQLSGFTLILIIAGGFLLFWLLFIFAKRQIMRFTLRSHRGPHAPIGLDAKKSLRREILRRIEALPKITYEPHVLRDDVDQKFSQEGATKPCHYHRMKAVDDAKNLEISMLKRKLSKRHSFESLRSYFIVILTPQVDPRVVHQFCDLYEAARYNPKPFGEEEYKAFTLLLKQLRSAVITLQPKSSIRSPAKTKASSSAPQSSSNDDKSSASLSVPYIRRLSKKKWNTADSDEETALCHSSALHEVSIISSDKDESTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL12</accession>
    <name>A0A1D2NL12_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low-density lipoprotein receptor-related protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL12"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="297" mass="33757" checksum="92F97B61EB064AF6" modified="2016-11-30" version="1">MQTSSSAPLSPIMGFKISHLPYFIIILTLLLENFSVFAVNSPQMTFYTPESHESFVHLESKYGNSATLSLKRPKPFLQFKANRTMMNATFPKREKLTEFIVLGPEYPFAGVSAIIQEMHLRTNHNNNGCKDFVQFAPNESPSTRSHKICGHIDKETAWNGSSDPRLQRTFLNPDGRVHVYFYSDENLEPESEDDYDQDIGVTVVFTSYTVCPSPANSWKKLKSCSQSEKMSCIYSTLFCDGKIDCGFYGEFGIDEEGCYIPYIYMTLSIVGGFLVAGTLIYLFVSWVTKIPKQYRHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLV6</accession>
    <name>A0A1D2NLV6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Voltage-dependent calcium channel gamma-5 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_00489</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLV6"/>
    <dbReference type="OMA" id="YAYPGPY"/>
    <dbReference type="OrthoDB" id="6126739at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004031">
        <property type="entry name" value="PMP22/EMP/MP20/Claudin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21215">
        <property type="entry name" value="LD36024P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21215:SF0">
        <property type="entry name" value="LD36024P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13903">
        <property type="entry name" value="Claudin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN06231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="288" mass="32406" checksum="6C81914F103B1122" modified="2016-11-30" version="1">MPCSAVTLSLATIAAVVSTALLAIAFSTDNWVRIDVKRTRLAEKIRDENITPEELQSNPIYYSRTEGLFRICFPNDRPKGKAIQAQLYLSPTETYCMNIDYYLSGDENSTADFTPDEHTKLYMGRGMIVLFILAFVFVFIAFWTGVAGCWRRSSGNITATAILMLLTCLFSAGGMGLWHGVEYYETEKLTGSNYFKDWPQGLKSSSVWSYDWSYVLAWIGVGWALIAAILFSGAAVCLRGENSFGGLENQHLHYLMPVYPQKQPGYAYGYAYPTPYAYAQSTQYPYNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM06</accession>
    <name>A0A1D2NM06_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin interacting protein 3-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000008">
        <property type="protein sequence ID" value="ODN06267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM06"/>
    <dbReference type="STRING" id="48709.A0A1D2NM06"/>
    <dbReference type="OMA" id="PVDYMSE"/>
    <dbReference type="OrthoDB" id="6022652at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1540">
        <property type="entry name" value="Actin interacting protein 3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022782">
        <property type="entry name" value="AIP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051825">
        <property type="entry name" value="SRCIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741:SF10">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN CG32809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741">
        <property type="entry name" value="P140CAP/SNIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03915">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Actin interacting protein 3-like C-terminal" evidence="4">
        <location>
            <begin position="189"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="769"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="858"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="973"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="644"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="895"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="914"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="976"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1031" mass="114258" checksum="1161F19AB5B90018" modified="2016-11-30" version="1">MSSHLRLASSGGGSGGGSSGSSSGRHHHHHHHHHPSHQQPSSRSNGPSGRRTLKMDMQSPTSARVANPSTTATSRSIDGSYIPGIYANHPKPLAYSHYRNSGSVASSIYSEPIHRSHPQPYKQGLFGGQRGTLSRQPPPSSTLFDDDPGIMSEAETSSTGFRRGGKARSSLPVVRTPSKTLERPLGLVFLQYRSETKRALLPNEITSMDTVKALFVRSFPKQLTMEYLDAMNVKIYIHDGSKDMFYELEDLRDIRDRSVLRLFEPNINGNGAVPSWDQDQSYFSEPEFDSDYQHQHIHKTKVSGRRSSFFYCLITVMKGSKGSPYMTYSYPVGATLPRVTRSFSPASVPIKQEAPPKPQRQSQYPTVTKRPIVVSPSPALYSPRGGDAARSSFPLPPPASYTPTDLRRVLIGLGLPFCFPPTDPTYIASPERRFVEDPYYQFPPPRSGSITPVIIDEEARFRMEHMERQLANLTGLVQKALVHPPVTNQPSSGILPSSATLPRNVIITPGAHAHPNQNAVGAVPPPVSSLYRDYIPTRDYRDRVLKPVPSSVPKPPAPAQRQPWLMFLRIRMTDRDLGLSPEMYNQLRMLQKKAKELKTDIKVLRRNVQAQAHTVRETLRDTFLRFKVVTMSGSDQWMQGDPEKEKIRRDEELYKQEVMKLEKDLSELELTVEELRSHVINKRMRVNMSDVENMALILSKSSKSVADLKVRFPPLHESVKTLLTSDVERMAVEECFLKEEPERLESALKRCKKLTGTLVTLKRLASVQEQRLPSQEDSAPPGHFPPQSSQVAKTNNRYLKQGWKWSSHFKQEPSSTTQCSIISPGSLVGAPGLGGHGPGATSSPENALDDLLNEISGGSVIPQKNRLGPPDPPKRLPSYPSTESGVALLDSPLKLHPPLPPKPTKIPPPPPPRISSKSPLVSPSIESSGGDSSESINSQDGGGPNSKLSQRHQELLRKQRQLQEQYNRLQLLQQRSTSSVTSAASNNSDKSELKKTGSESNLRAKLGLEFSAAPTGSLSNINKPLYETDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0G7</accession>
    <name>A0A1D2M0G7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase-like protein 7A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01009071">
        <property type="protein sequence ID" value="ODM59402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0G7"/>
    <dbReference type="STRING" id="48709.A0A1D2M0G7"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM59402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="121" mass="14194" checksum="63D37BB939EC6A51" modified="2016-11-30" version="1" fragment="single">MILELLGFSLVLVLVFIAWFLLKHGHRYIGTENRHKFFAEFFKEFPVFHNAKTGFYKKELFKPLHEMESSFPELRKEKAIRILEIGAGPGANMEFYPKNAKLIVADPNPFFKEILESVFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0S2</accession>
    <name>A0A1D2M0S2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20067</name>
        <name evidence="1" type="ORF">Ocin01_20128</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Gilbert D.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <reference evidence="1 3" key="2">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008298">
        <property type="protein sequence ID" value="ODM86554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LJIJ01008004">
        <property type="protein sequence ID" value="ODM86615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0S2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="30" mass="3301" checksum="8A540D20607A1724" modified="2016-11-30" version="1">MQLMAAVAGPVTYFVEVEENLAVVHVLQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1H8</accession>
    <name>A0A1D2M1H8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007140">
        <property type="protein sequence ID" value="ODM86813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1H8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="14310" checksum="381E4D2BCC437884" modified="2016-11-30" version="1">MITNRSGRPSSLRLVMMATERQADFVWNSTTPYRFPSRRPQTRVYVPIRGELVTRPSLPKRNSSRKRDVAIADMQQFSETGVTLRNMTLSIHTLMSKLSPALEVTGLLVESPQYGLRLQTVFNGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1T3</accession>
    <name>A0A1D2M1T3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cdc42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006749">
        <property type="protein sequence ID" value="ODM86925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1T3"/>
    <dbReference type="STRING" id="48709.A0A1D2M1T3"/>
    <dbReference type="OMA" id="TNVECSA"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003285">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="147" mass="16469" checksum="E875A6A2F432076B" modified="2016-11-30" version="1">MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDDAGTIEKLAKNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRKCAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2F4</accession>
    <name>A0A1D2M2F4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19534</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006040">
        <property type="protein sequence ID" value="ODM87148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2F4"/>
    <dbReference type="STRING" id="48709.A0A1D2M2F4"/>
    <dbReference type="OMA" id="QENYLHY"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000395">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036578">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="7">
        <location>
            <begin position="242"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="912"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="181"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="955" mass="107440" checksum="D6B473DD38B78FE4" modified="2016-11-30" version="1">MKVNKPGSRSSSQRVLRSSSGAAQEKTKKDDPLNVSCENSDREDALPKKAGKGARGSGKSNLRKSVIEDDDSDESSDGEEVGRSKRKARVLSDSDEDDLRSSEGKFPVDKSAAKKQPKSNQGMHLCRPRRLDQRKPLKSKYNNKGHEQLNGLCLKMMKRTTFPRKDPQLRDQQRNKVFTIDTDDEEEDTEDEEMDTEEDEEMDSDDEEMNSDDEEEMDTKPAKKTNTKRSVKRNKLGRQDIGTPDCLKNQVFVMAGVLHSMERDECKNLIIKYGGRVTTTVSGKTNYLIVGENPGQSSLKKAKQLKTPQITEDDLLEMIRNGTAQDSGLDYTPGVIVGQMKTESDDDLDYSIFDTPPKKEEIAAKKKDLVPKKQKAVTLLKKDPPRKVKEYENVAAKVETKSALPSSSTLPAAPIVVPPAAPEELPPATPVVFSPAHELLWVEKYKPQTLDSVLGQGLSWSNSGKLVRWLQNWFIYHGTSKNKVKAAPKTGFKDAEGKTFKAALLSGPPGIGKTLIAQLAVHEVGFDALELNASNQRNKKELHETLQTHCHRKLTRKHVLIMDEVEGMFSNEDRGGLQELVELIKTSRVPLICICNERFHSKIRTLATYCFDLRFYKPSLQQLKGLVSKVCFAENIHIPQERVQQLITSSDSDARQILHQLQLFKEGKSDQAYNPQKNLKLGPFDVVRKVFVKSERDQMSIDDKAELFSQDYNLGHYTYLQMKPTAAEGRPCKHLDLIAKTAGSIADADLIESSQTPELLPIQAVFASVMPGEYMESTWMPRIQFPKWLGKDSTKNKNRRNLLSLHTHLHSHISGSLEALNMDYVPYLSRAIINPLAIGDHQTAAEVFEDYTLLRDDLDSLIDLSKWPGIREKSIESRFKAAFTRSYNQNSTARAYPQLVKGKKREGFSTLEDDQEELLEEGESVLAEEEEEEDESIEKDTNVKVFGGARLGKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M301</accession>
    <name>A0A1D2M301_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxysterol-binding protein-related protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005519">
        <property type="protein sequence ID" value="ODM87345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M301"/>
    <dbReference type="STRING" id="48709.A0A1D2M301"/>
    <dbReference type="OMA" id="NKYESCS"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3490:FF:000001">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF200">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="16802" checksum="7B5B56192826013B" modified="2016-11-30" version="1">MYWICAQVFSPEDKKKPFFTVDGEWNGAMVGKWSDGRTEKFVDVRQLKIIKKRTRPMVHQEVFESRRLWKDVTRGLKHRDINKATDSKSFLEERQRQEARERSSRGETWKPRFFIPAGDTWIFSEPLEQRLKKAQQRGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M437</accession>
    <name>A0A1D2M437_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_18949</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004784">
        <property type="protein sequence ID" value="ODM87733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M437"/>
    <dbReference type="STRING" id="48709.A0A1D2M437"/>
    <dbReference type="OMA" id="ACHFIND"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019427">
        <property type="entry name" value="7TM_GPCR_serpentine_rcpt_Srw"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF22">
        <property type="entry name" value="PROCTOLIN RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10324">
        <property type="entry name" value="7TM_GPCR_Srw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="63"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="401" mass="45454" checksum="0454FEFFD8140B79" modified="2016-11-30" version="1" fragment="single">ARATMYADSLLNEYLSVSSLDAKFTNITPDQKYPAGDVLFRDLSRFWVQFISVPIVVVVGVLGNVIIIHVLTRKSMHSSTNVNSLRELLPETFSACHFINDCRYLTALGISDLFYLLFTASMSWRHYPSFDRFWLYWSYIPIGLWITDAFSSTSVWLTVSFTVERYVAVFHPISGTNLRGEKRAVSIAIAMYILCFAFTAPTVFEWELFASGKTPSLYTEQSIYSVNGPHLARTKPSVFFITGVRKTRIARNTPIDDFREDTISARHIQLGICGIKKAFCVVFQRQREENRVTVILIAVVMLFVFCQLPTAAVLIYSSFISLPASGSAEENILLGLGNIFNLLVAINAASNWVLYTALSEKYRRQLCYCFMSNRHANRTVPARVNNAYDLRQFPAGIYNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4L6</accession>
    <name>A0A1D2M4L6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock 70 kDa protein cognate 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18830</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004545">
        <property type="protein sequence ID" value="ODM87852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4L6"/>
    <dbReference type="STRING" id="48709.A0A1D2M4L6"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000028">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="311"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="42839" checksum="9F402F44E27993BE" modified="2016-11-30" version="1">MIPPEQISAILLANLKSQAESSWRAATKDAAEMAGLEVLTILNEPTAAAIAYKMEHFSEKPKKVLVFDLGGDSDSKPKRENARRMIRRLQTYCEKAKSQLSSAMHATISVDGLAQGHDFHEVFSRTKFEELNKTLFRQTIEVVDKALEGAKLKKKDIDDILLVGGSTRIPKIKEMLSKHFNNKTLSHSVHPDIAVAYGAAIQAALLNGKKVNQLMVVIPKNTKIPHRATESFRTSFKNQDFMRISVYQGDDAIAANNNLLGTFELSDIPPSKSGKESVDVTMEIDKMGILQVTAMCRSTQETQSLIVQSNKDRLSEAEKQKISNSIRKSKVTQKYDGFPDNKSSDDESTGGISSDDEPIKKPQSFKNQSAGLSESSSDSETDDLEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4L7</accession>
    <name>A0A1D2M4L7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">oxaloacetate tautomerase</fullName>
            <ecNumber evidence="5">5.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Fumarylacetoacetate hydrolase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18754</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>oxaloacetate = enol-oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:16021"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17479"/>
            <dbReference type="EC" id="5.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:16023"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.2" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01004397">
        <property type="protein sequence ID" value="ODM87927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4L7"/>
    <dbReference type="STRING" id="48709.A0A1D2M4L7"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="6">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00042340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM87927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="19836" checksum="6F9BF20F0F446832" modified="2016-11-30" version="1" fragment="single">DHAAELGNAVPEIPLLFLKPASSYITEGTPIKIPKGCTSLHHEIELGVGTDIPEGSAMNHVAGYVLALDMTARDFQNIAKKKGNPWDLAKGFDTSCPVGKFIPKDAVSDPHNLELWCKYPYLISYISQYFTLEPNDIILTGTPPESVASTPVISSKVDLATWLKLSSRSRAKLVDHKYSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M546</accession>
    <name>A0A1D2M546_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposable element P transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004197">
        <property type="protein sequence ID" value="ODM88044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M546"/>
    <dbReference type="STRING" id="48709.A0A1D2M546"/>
    <dbReference type="OMA" id="TWFSYNE"/>
    <dbReference type="OrthoDB" id="6485269at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048367">
        <property type="entry name" value="TNP-like_RNaseH_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21789">
        <property type="entry name" value="TNP-like_RNaseH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposable element P transposase-like RNase H C-terminal" evidence="1">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="308" mass="35276" checksum="31863013734DC5D9" modified="2016-11-30" version="1" fragment="single">GSEGTEEFTKTLNDVFDACNARAKREGIRPLDKKFMTYLFFRLIQNFQSNLCQSDTFASDLTLASIRVTLRSILDVIIYLCNELGFDYVLTGKFNQDCLEKFFGLVRSFGGDNSHPTATSFSHIFRLLSIYCPTSTIIKGNVRTNEETSGAVTSYVETLNELRLTAQEKNKKVRSDLEDLVLEKIMYSENEAQFVNEQFNDNQDHSFVVYKAKSFTKCLKCLDMLEDDNPIGSDMTLTAMKDLGGLKYPCRELFVIIQNMVEPELLNHIQTQHADSDFSTVCHYYLIWLFTMSRLDCGSIQETRTVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M579</accession>
    <name>A0A1D2M579_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004173">
        <property type="protein sequence ID" value="ODM88061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M579"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="73" mass="8173" checksum="1E9F6C954F0518DD" modified="2016-11-30" version="1">MMSAALFGTKLPLPEKVITSEAQTHNGSVHYKDDGKVNMYTDWRAATVKLQQLDVSPDRCKEIMMIPSIAHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M660</accession>
    <name>A0A1D2M660_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003568">
        <property type="protein sequence ID" value="ODM88465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M660"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="188" mass="21962" checksum="339DCE3958A6E5B2" modified="2016-11-30" version="1">MKPGEERRFQSQGLFIVVFFKNEKCTEEDTGALDWFERLSVSRRNVHRGNIYLPHPDCSLYIICINGEAFEEQCRVPLYFNPERKTVNFQTQFQNVWRNEASCFHYHFRKTNRNNYSQPPVTDVPPPGALTQCGQTIKADSGYIQYKLNQNYNSGELCAFLIQLDQRELCDFTLEAHGIIDMSSLLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6D0</accession>
    <name>A0A1D2M6D0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003453">
        <property type="protein sequence ID" value="ODM88535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6D0"/>
    <dbReference type="STRING" id="48709.A0A1D2M6D0"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM88535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="103" mass="11389" checksum="CB0BA495620CED38" modified="2016-11-30" version="1">MENTTSSSFYKEQGEKNLQSIVGDLFVAGSETSSNSLSFATLYLSQHLGTQRKAQAELDRVVGLDRQVFLSDDKTLQSHLKSFKLGMEIGKDTDVVDSEILKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6H8</accession>
    <name>A0A1D2M6H8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003408">
        <property type="protein sequence ID" value="ODM88587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6H8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="35" mass="3940" checksum="042574B97B334195" modified="2016-11-30" version="1">MIGHGMTMGLCSQKLPPWHGNVPRNDHGIIEKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M752</accession>
    <name>A0A1D2M752_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003236">
        <property type="protein sequence ID" value="ODM88752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M752"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694:SF11">
        <property type="entry name" value="LP21121P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694">
        <property type="entry name" value="PASIFLORA 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="37084" checksum="4ACAF9ADAF18780F" modified="2016-11-30" version="1">MLPNPCPCMSLQTGVKSVAAVEAVGNIIGIYFPVTSLRLNKAREKPDSEWINEWATTIWVFIVAIFIILTLAFVMAFVLFVGAQKKNITLCWAWIGFTSTLILLNTITFIVAVAGSYGELRSFLSPGIRELISVLFETYFVFVVHAFIKQLNRRQENEREKTISIEPGESALAELLLNPSNLGAHPRLGGRVDATPLVTFYYIFSLTGLVVAIVLYLGAHKKNAVMCWPWFVFTAIFVVQAFVNAILNFTGAYGEAVILRSAGVGNLFEVAIESYLMFVVYAFIMQLRRGPRDPLLGVVTEAPSRSQSQLRRSIHTAMATGAYYTAEQPEPPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M793</accession>
    <name>A0A1D2M793_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003175">
        <property type="protein sequence ID" value="ODM88794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M793"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903546" evidence="1">
        <location>
            <begin position="20"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="96" mass="9314" checksum="07CED35A3EDFD923" modified="2016-11-30" version="1">MHKFIVFACLFALVAVASAQIGLGLHGGAGYGSLGFGNIAGVNSNQNALGYQFVTREGGPLGGRVHAQAAHAPLGVGIPVVGGLGLGYGLGGGIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7R3</accession>
    <name>A0A1D2M7R3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thyrotropin-releasing hormone receptor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thyroliberin receptor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_17683</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002993">
        <property type="protein sequence ID" value="ODM88999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7R3"/>
    <dbReference type="STRING" id="48709.A0A1D2M7R3"/>
    <dbReference type="OMA" id="MSIEANC"/>
    <dbReference type="OrthoDB" id="5987936at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004997">
        <property type="term" value="F:thyrotropin-releasing hormone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002120">
        <property type="entry name" value="TRH_rcpt_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46061">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46061:SF3">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="54"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM88999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="35818" checksum="71CF8C6C16D17778" modified="2016-11-30" version="1">MGEMSIEANCSESETTTEFSTIIEGEVTLTYFSKIYQITGTLLQGPLFLLGFVGNLLLVFVVARSRSLWTPTSCYLVSLAIADCILLVAAIPQEIVGYYLIVNQWIWGDVGCMLLAFWQNLGITTGSLSVVAATIECYLSICKPLATQTICGVCRALKIVLILWIFSIVYSFPWIFLTATYPVYHQDQPIYSTCDHKICHEQYLTYFYSDLLLFYIIPAFLSIFLYSKIAYTLIHHSIKCCANTVHFQNRIQIVKMLSLISALNALLWLPYRSVLVYNTLAEQNALNPILCCTMSTKFRRAFGNALNPIGSKPHKLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7U1</accession>
    <name>A0A1D2M7U1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002946">
        <property type="protein sequence ID" value="ODM89050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7U1"/>
    <dbReference type="STRING" id="48709.A0A1D2M7U1"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="168"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="303" mass="35091" checksum="97051E1CF7FFF17E" modified="2016-11-30" version="1">MSQMHFSTVFISVVVLYAGICCNVSAISVEKFLTMTLSQKVTLDKFRAQVMPLLKDSYMKHDTYLIRWLRARNFDINSAEAMLRENLKWRKQNAIDEMRSEDWSDIASDFHVTIDTYDKTGRPSESATNYIENIFRNKKVNVSNFLVGVIDIYDWDIRRAVIQGKGARMLRYLTSRVENITGQVYERQEQLGMNVTQIVVMGSAAGFNIIQHACPGCLPLWIQFALMIENYYPEILDELIVIDAPPTIQIVLEAIKPFITRSNREAIKVLSSNRSKWMAYLDNKISREERRREYGGTKPPFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8Q0</accession>
    <name>A0A1D2M8Q0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coatomer subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_17331</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">COPI-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002707">
        <property type="protein sequence ID" value="ODM89350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8Q0"/>
    <dbReference type="STRING" id="48709.A0A1D2M8Q0"/>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="39"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="81"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM89350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="259" mass="30080" checksum="41DEF24C17475032" modified="2016-11-30" version="1">MLVKFETKSARVKGLSFHPRRPWILARSEELLSLIFNNLSVHSRSTSSRLSFHNQQLFVSGGDDYKVKLWNYKLRRCLYTFLGHLDYLRTTYFHHKQPWILSASDDQTIRIWNWQRLRKKQTERSKSPIEGRQNNTRSPDLFAPPDAVVRHLMEGHSSGVNWLDRERPAFAVHGNLIYYIKERLLRRLDLTTSKDQAVLQLKGGPRLNVRSLSYNPAENTVLLTTRPPNSDNGSYELYVIPGDTNSSQPETAECKKGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9A7</accession>
    <name>A0A1D2M9A7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_17174</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002578">
        <property type="protein sequence ID" value="ODM89512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9A7"/>
    <dbReference type="STRING" id="48709.A0A1D2M9A7"/>
    <dbReference type="OMA" id="NCIVCEC"/>
    <dbReference type="OrthoDB" id="1166527at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM89512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="81" mass="8778" checksum="3E221B48F91E83FD" modified="2016-11-30" version="1">MPPKTSGKAAKKAGKAKRTSPKETERSRIAAEASRLAHYNKRTTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA21</accession>
    <name>A0A1D2MA21_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 4C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16889</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002358">
        <property type="protein sequence ID" value="ODM89791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA21"/>
    <dbReference type="STRING" id="48709.A0A1D2MA21"/>
    <dbReference type="OMA" id="ESNENCA"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="511" mass="58263" checksum="930F1525C8DA5435" modified="2016-11-30" version="1">MESIEAQTILKSGLVTSFLVLSVCLLLVKAFTQSYFGNKSITKKLRKNKQTAWEKLPKFPIFRGILLLLDLRSAIEKYSRLAEGLGPVFRVMIYGEEFAILTNPSAIQKLLSSKDEGHIVKSPKVYQIIKDMTGNGLVMSSGQLWHTNRKLFAKAFSYSALKTYMQIYNKCASRLTAKLERIGEKHGFSEYQKINWIIHECGFDVITETVMGLDQIVNKEDSALMFTNLNSAKNAAMIKQVFNAQPWLAPLFQLHPSSIKYRKSLYNIDSIIKKMITQFRHRAGEDKDADEDSFENMLAFMLKSGLAEDVILAEVKTMLLAGYETTSSTIHYLFFMLALHQNHQNACREEILRVFDKCPDGQLTMEALSELKYLERCIQETLRLFPVIFTIARKLETPLIIGNGSNVAVSILQLHRSPEYFPNPDEFQPERFLPENCMGRHSFAYVPFSSGPRSCIGMKFALLEAKTIAAHVLKEFELYTSDTMKSVPNMPSILLKPERAFYFLLKKRSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAU0</accession>
    <name>A0A1D2MAU0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002207">
        <property type="protein sequence ID" value="ODM90051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAU0"/>
    <dbReference type="OrthoDB" id="8284999at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.15.10">
        <property type="entry name" value="Proaerolysin, chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="227" mass="24880" checksum="61E19281AFC5FC21" modified="2016-11-30" version="1">MINVTLIQDGSVKPKRMVVGSKEDQNATFVSSGHTDNKSSKNYEQLCDPGQAFTGISVLVDEGGGIKEWSWMCDNVLDPTEMCEPQESLGLVLQCDNSESGNELECSYSKTIGVGVSTTITETERQEMTFSAEFGYSIENGIPGLSASMSASLGFSELVGYEWSRSDTTTWTEETTVQATMKVRPYAHSKLEQLVGKCSFYGTSVNFFKQTDINVTSGEETISYFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB60</accession>
    <name>A0A1D2MB60_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase family 92 protein</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01002092">
        <property type="protein sequence ID" value="ODM90238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB60"/>
    <dbReference type="OMA" id="RIRRAFY"/>
    <dbReference type="OrthoDB" id="2526284at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF40">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM90238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="540" mass="62113" checksum="17F2408857B393AD" modified="2016-11-30" version="1">MDNFVPIHDSRFESSNEPIPTLKPESIYQRFFPLFKIGEKRRSRKPDFPDKVSTSYEKPKLSRASKQKQLDWQPVKGSQYKFSVYSAYSYNKTEVVIIATTKSQTKEKVACVFHFDNGQKIQTTIGKVETMGEHWGMMYAGTFIRCPLPISSDFTMPHSVSVTVINSNSSKVNGHVDQEATMLGNPLIIQYKSEEDLSNPPFNFSVCVLPTFNYNEVFHFLEWLEFYKLLGVRHFTLYNITIGPDTSCVLKELMSSAADSGIVVDVHPWHDFPIKKNSEIRSGPCGECGLSAATNECIYRHKGLSKYMIFVDFDEFIMPRSAQDYGEMIRSMDVMNKSVEIGEYSIRTGFFGRFRNNDELRVDMCEELKRKNSVFTYHVCKHLLMVKKSLREETILMHNDRSKYIVKPEAVLEGGNHHVIQLDSGYETLVAPPEVAIVRHYRFVEGFWHIPKNTSAVPDRISKSFGVELAKKAELNVLKTIPFDLIKFNVLIIEVYFYSEAEKTELDTLLTSNGYQFVKNIEVDKIYIHKSVSYMLDKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBD4</accession>
    <name>A0A1D2MBD4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002065">
        <property type="protein sequence ID" value="ODM90273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBD4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="20638" checksum="C7013332A3820A35" modified="2016-11-30" version="1">MDVSIDFNVDGASALTPPQFLTACGIQENAGGSWGHGFGDSPKILWVGIVSLMHHFEAALTSLEGFCLAWIALKTWNWLPKEPSTFGRHEVFENLNTSEEYNLLPGNSPESTRRLLSACTSAFKLSQPEPEKEIPASDHDGGTEGVDDDASIEENDANGSKSSCFRQFVLFRLQYSFQNTMRMSSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBS6</accession>
    <name>A0A1D2MBS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001952">
        <property type="protein sequence ID" value="ODM90457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBS6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="215" mass="24995" checksum="90D92AE54C435F37" modified="2016-11-30" version="1">MEAKCSKMSVNLSKTDDDDWVEARIEEIVRKMTEDGPRVLKIWNECQLIKQLFADYSDFFVSVQQMTRENRQLLSVTLKVLQVPVIIQLVQQYRGIVAGIGDAAELFSNYLREELLPTSQTFLEATHLFDPDNFNKWLPIPVEVEQRAEEPPVDIKFLKEDSRIIRLFNTDVEQLEANWKKINTEEQLKTTLADAKQLYAQLPKNFRTVAFKGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC62</accession>
    <name>A0A1D2MC62_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transmembrane BAX inhibitor motif-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001909">
        <property type="protein sequence ID" value="ODM90560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC62"/>
    <dbReference type="OMA" id="YICYSSF"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001234">
        <property type="term" value="P:negative regulation of apoptotic signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF127">
        <property type="entry name" value="PROTEIN LIFEGUARD 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="31869" checksum="5F26543172F7C906" modified="2016-11-30" version="1">MTTANYPEYQDPYASGNVTVPSTHGYPTQGHATSQQQYILVVDAPEEQIIIEDLDEMTGFRHKPTRMSFVRKVLGLVAFQLIACTGFMALAFLNGDLKSFLMSTAGMSLSIVCLLAWMGLFIAVGCCKVGRGKPNGLNVSLFIISTALLSIYSASIVIYFEIPDIMIAAATTVGVVTLLVLITMLTKIDITGYMIYILGACLALFLFAFISSLLFGLGVIPYEKRLLLQTIITGLFAVLFAIMILYDLKLIVGGGRGGQYGEQDWLIASISLFYDILMFFLQILQLGELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCF4</accession>
    <name>A0A1D2MCF4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Netrin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_16025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001860">
        <property type="protein sequence ID" value="ODM90653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCF4"/>
    <dbReference type="STRING" id="48709.A0A1D2MCF4"/>
    <dbReference type="OMA" id="KSQDFGK"/>
    <dbReference type="OrthoDB" id="9972745at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016358">
        <property type="term" value="P:dendrite development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008045">
        <property type="term" value="P:motor neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009888">
        <property type="term" value="P:tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050440">
        <property type="entry name" value="Laminin/Netrin_ECM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008211">
        <property type="entry name" value="Laminin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056863">
        <property type="entry name" value="LMN_ATRN_NET-like_EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574:SF365">
        <property type="entry name" value="NETRIN-A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574">
        <property type="entry name" value="NETRIN/LAMININ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24973">
        <property type="entry name" value="EGF_LMN_ATRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00055">
        <property type="entry name" value="Laminin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00136">
        <property type="entry name" value="LamNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51117">
        <property type="entry name" value="LAMININ_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Laminin N-terminal" evidence="6">
        <location>
            <begin position="70"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM90653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="36692" checksum="EDE1BD3FF6F5EB12" modified="2016-11-30" version="1">MDPLSLSSSSLIVSAAPSSSSSSGYFKTFGYSSSGSMYDPCYEDIAASSANSYVLQSSALGISASSGVKRARKCIPDFVNAAFGKEIEASHTCGSRVATRMRRMKDAAAGTCHVCDARDSRTSHPASYMSDLNNVNNLTCWQSDPLASQEENVTLTLSLGKKFELTYVSLQFCGSKPDSMAIYKSMDFGRTWQPFQFYSSQCKKMYGRPNRATITRANEQDALCTDSHIKDLGMGNRIAFSTLEGRPSAIDFDNSPILQTFYGVADFAVGGRCKCNGHASRCIHNKEGELVCDCRHNTAGRDCERCKPFYLDKPWGRASSRDPHECRGCVHVKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDB8</accession>
    <name>A0A1D2MDB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Voltage-gated potassium channel subunit beta-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_15707</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001716">
        <property type="protein sequence ID" value="ODM90975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDB8"/>
    <dbReference type="STRING" id="48709.A0A1D2MDB8"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015459">
        <property type="term" value="F:potassium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044325">
        <property type="term" value="F:transmembrane transporter binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901379">
        <property type="term" value="P:regulation of potassium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="134"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="22659" checksum="9A28C909C1E197A1" modified="2016-11-30" version="1">MSSHTIWDSILDKALNREPEPPLNENKPKSHSADKTKGLNEDNKAKVLNEAKANSSDKDRTLNKNKAIQAPLACNEEGFDEMEQLFLPDSNRSMGPMTNGTTPQQSPLPASGRNPTPGLRYRNLGKSGLRVSSIGLATWMLTQDSNADSAEKVITLAYESGINVFDLSEAYSGQTAEEELGKILQKKAWKRTSYNVVTKIYWTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDL9</accession>
    <name>A0A1D2MDL9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">F-box/WD repeat-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15699</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001713">
        <property type="protein sequence ID" value="ODM90981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDL9"/>
    <dbReference type="STRING" id="48709.A0A1D2MDL9"/>
    <dbReference type="OMA" id="NPRDSEM"/>
    <dbReference type="OrthoDB" id="192402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042508">
        <property type="entry name" value="FBXW5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20995">
        <property type="entry name" value="F-BOX/WD REPEAT-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20995:SF17">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="609"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM90981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="671" mass="76792" checksum="571CF93940EF8F39" modified="2016-11-30" version="1">MEELPDSLLLQIFDYLDYKDVTSVSKTCRQLARVANDEILWRNLFHRHFVISPNKFVNPLSGDSWRTEFVRLIDEVPIVETEVVTKHTDQVLHVAFSHDGKRFATTAKDGYVYVWRSGYPVKLEYSQNMKTFSWKYTQFSQFNESDSLLLVSGVLFGLHSTSGEIAIFSLKDNFELQCRTMSKPYDIFGSWYSEMFFLSGNLHWLGQMVSKSVIWLNKASQEAESEHASVMNELYRFYNPKASSVRSLMVANCVEVENPPNGESSRSAANKKQTDQTKSSQSLDSRDIRTGNPLSNLPLERELMDREGPSSQRSLQGGFQSWKPFENVSDINYSDGYCSERSPGQSSSRASLQSPSDLDSTDNSIEEPYESTSQMDKEHLSCLGGTPAKRPKSQKQHGDQRDASPSKCSIEDESEDDFLDPRPKWLIFTCGSKTYTPHQLGFKKINPMTFNGKIDPGPTLKERIEEYKRRKQLERTGEQDPSINWSDHARVAHRFDEVDKIIDLHGHVIGMALSPDHRYLYVNSRPWPEGYRISSELDPPPIAQEIDLHIIDLTTLTQVGMMRRAHRAYTPNDECFFIFLDASDLYLASGAEDKHGYIWDRHYGISLAKIPHKDVVNSVAFNPNEPEMLITVSDDMTIKIWRSRNLCRRLQINTEKLRFGTTLYNVPKGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDY8</accession>
    <name>A0A1D2MDY8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytoplasmic aconitate hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_15448</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001623">
        <property type="protein sequence ID" value="ODM91228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDY8"/>
    <dbReference type="STRING" id="48709.A0A1D2MDY8"/>
    <dbReference type="OMA" id="NGGIMQY"/>
    <dbReference type="OrthoDB" id="2279155at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006757">
        <property type="entry name" value="PRK09277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="5">
        <location>
            <begin position="60"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="816"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM91228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="871" mass="95725" checksum="4386A9F3CC1D07D1" modified="2016-11-30" version="1">MGHQASATDLTNPYGSLRKSLSINVPEGPPVEAFYFDLADGFGEHYSRLPYSIRVLLESAVRKDQDVEIQFSPARVVLQDFTGVPAVVDLAGMRDAVVKLGGGLKRQPCLSYGSCHRPLRSGRFLWRNEDMEFQRNHERFAFLKWGAKAFENMLIVPPGNGIVHQVNLEYLARVVFTKSPEKELTLYPDSVVGTDSHTTMINGLGVLGWGVGGIEAEAVMMGLPMSMVLPQVVGYRITGSLSPVVTSTDVVLTITKNLRQLGVVGKFVEFFGPGLANLSIADRATISNMCPEYGATCAFFPVDSITIQYLRQTNRAERDVALIEAYLRKTLMFREREDEDLVFSEVVELDLSTVVTCMSGPKRPHDRVNLTDMKEDFQRCLVGKIGFKGYGVPNEKLGSPFRSRLRTESTHSSTGPCSLLPSPAAPILRTHQLWLLARKAVQLGLSVPKYIKTSLSPGSGVVTYYLNESGVIDDLKALGFDIVGYGCMTCIGNSGPLVEEVEKVVENSDLVCCGVLSGNRNFEGRIHPLLRANYLASPLLVIAYALAGRVDIDFEKEPVQGDVFLSQIWPSREEIRACETQHVIPSMFKNVYSKIQSGNPRWNELKIEDSALTFNWSDESTYIKRPPFMDNLEGVEDNDLIGSVCLLYLGDSVTTDHISPAGSIARNSPAARYLSGRGLSPKEFNSYGSRRGNDEVMARGTFANIRLVNKLCKDAAGNTLPGPRTLYIPNNEIVRSNSQYTLTFSFNIQYLAGKRLTARKPQGLGCKGPPAPEHQGDHRQSRTIADIHRSNLVGMGILPLQFVNGETAESLGLTGTRDIQPAPRLGRTSARSPGSTLHVEAETTNRSGGILPFLVKRIAKDSYSSVIIQCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MER0</accession>
    <name>A0A1D2MER0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase/endoribonuclease IRE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001541">
        <property type="protein sequence ID" value="ODM91465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MER0"/>
    <dbReference type="STRING" id="48709.A0A1D2MER0"/>
    <dbReference type="OrthoDB" id="63989at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="66"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="619" mass="69606" checksum="245515F66D5A5590" modified="2016-11-30" version="1">MHSLPGANSAAQSTKLYRKIVTRQNGFTNLMDILKETNQTEARNILKTAIARWRHTILYEVNRVSYDPNTILGKGSNEAVVFKGKFAGRDVAVKQVNSGSKQEKIVINEIENLKKCDSQENIIRYYGTTVVENFILIVVELCEISLKDWLPAKPLCISPAEILRQVTVGLKWLHSKRIVHRDLKPGNILLTSSHSIRAKISDFGLSRKIEEGRNHVLSCGLGTQGWIAPEILLQFDENISAKYKFTFESDIFSLGCVFYYVLTNGKHPFGGQVMRNANILIGKHEIDPQRLSCSAAENVKIITLMISKDVKLRPSCLVLLSSSIFMNHEDKITKCVENGDMDGVQPIVKSPRIKRSTKITSVSNKNDDLVKTFKKSGAESTSLITGNPVTKGNINMALTLKDVTHHSDNAKATASRLLENNYPAESSTYSSFINSNQLPPSSSQNINRWSTVEHSPRVQDGRSMLQFAKVCLETVEYLLHQQQFSKELPKNMHAALIIESMLVYNICVSSDEEFENKSYILNLILSLNPDLVNSGIDILNKALYEARRMHTKGKHVDVFRILLQHNADVNAADEAGETPLFYATKFFGKTPNYLGIVKILMEYQADPNKKIKEEKHFFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHC4</accession>
    <name>A0A1D2MHC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001275">
        <property type="protein sequence ID" value="ODM92302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHC4"/>
    <dbReference type="STRING" id="48709.A0A1D2MHC4"/>
    <dbReference type="OMA" id="KENIRWR"/>
    <dbReference type="OrthoDB" id="6146271at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="97"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="274" mass="31521" checksum="23A1D2CC2C0B8C36" modified="2016-11-30" version="1">MSQFFATYLVLGVGVLSGVGAISVDKFLSLTLSEKNALDKFRANVSPLLNDDCMRLDTYLIRWLRARNFDINSAERMLKENIRWREENKIGNIKNEDWSDLSGDFHRTIDTYDKIGQPIGVVDLYEWDIRRAMLQGKGQRLLRYVVGLVENITGQVCERQQKGMNVTQVVVLLNTEGFNVIQQACPICLPLWIQFVSVIENYYPEWLDELIAIDATPAVQIVLNAVRPIFSRSTNNAIKVFGPNRSKWMEYLDNKISRSERRKSYGGTKPPFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHJ9</accession>
    <name>A0A1D2MHJ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dual specificity protein phosphatase 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001221">
        <property type="protein sequence ID" value="ODM92469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHJ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MHJ9"/>
    <dbReference type="OMA" id="ETTVTYM"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008579">
        <property type="term" value="F:JUN kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="371"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="436"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="57760" checksum="783E45D692DBC5AD" modified="2016-11-30" version="1">MKRLLVYFSYIGTNYRGLQRTKLVSTNPLGSGAPDLETVQGILDFGLQKVIDKRISLSISSRTDTKVHALESTGHFDVDEGYFKKISYSPEKICQSLNLFLDKNECDIRVKRVVEVPTDFYCRGASSRIYKFRVAVLNHHPHNISSNLRVSSTTEITELNRCEVVAPPFNIDVVQDACKLFLGKRDFTTFMKSSSEVIPPEKRVKTLLRFSVSPESISDSQIDSEFYSICQSPYDIYVFTVEGSGFLRRQVRRMVGALVAVGRGIVNEKDIKWMLDNPSEKNWNPKIGTMGPNVMDNTKEVPSDEAESCSNFASLLQNRLKRGLKPTTTKTTYPDGSVQYSTDQGTLASVSQKKNPGLSFGFVVDEKPDLTVGLVYPWLLLSSQDVPNEPQLLLRFNVSYILSLLPGFLLIEASQAIVKKHLVLDVFDEEVFTLDSHFCSQAFQFIEEAKHHGETVLVHCNAGISRAPSIVIAYLMQFENLSFDNAWEQVKAARPVIKPNFGFQKQLRSMDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIA5</accession>
    <name>A0A1D2MIA5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001180">
        <property type="protein sequence ID" value="ODM92642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIA5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="412" mass="46015" checksum="7DEC53B8A4D0B15F" modified="2016-11-30" version="1">MLFVFVTSSSQNGTPNLSSLHGNIQETPVNDSREADGVISGWIRGRRTKVLDKPLESQLNFQETDNQDKAKDHDNLSTQKVPTFSLLSGYSVKNGSFGLEAEKSDMQRTDNQPNKSITVEIDYNIPEAGVAGNQRQNKNVAMINSKTSQKRRLRTKGKQESLFNDGLKTHDFKALVKPDINTNYIAHGPIRRQEADVSLISLATEGPIELTSVSPIESSFGGLTGLQSLPPLSILQFIKLLVAVTPFMIPIIFIPLLILTIGIFMIPVTRSNIFLDVGDFRSFKGYTTSVWSPYMGSIKNFTTSVVMPRALQFANEVSDHESCVEKISCEISARYLHDGWNGSWRSIANRGWISRIMSVLWRNHPTVGRIARSLDVDGLNAEESKSNKTSRSITNDCSRYTCQPITFIRKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIE3</accession>
    <name>A0A1D2MIE3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001175">
        <property type="protein sequence ID" value="ODM92691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIE3"/>
    <dbReference type="STRING" id="48709.A0A1D2MIE3"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="6780" checksum="CF56CA022DC93920" modified="2016-11-30" version="1">MAEFPLDPQLGKMLIAAGEYACSNEILSIVAMLSVPQVFLRPTRKILSGVLKTFSTSLPQISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIT2</accession>
    <name>A0A1D2MIT2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001119">
        <property type="protein sequence ID" value="ODM92910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIT2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10656" checksum="A4852815440DC589" modified="2016-11-30" version="1">MQGSLLKADQFPDMNSVNASITYWDIDDDLEITDKEKNAWKLEILNELLNNINHCTCPKLLVPFVCDNNRKLHSNLCYFKCVQDKAIQPLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIW4</accession>
    <name>A0A1D2MIW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001107">
        <property type="protein sequence ID" value="ODM92967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIW4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="56" mass="6377" checksum="64F97E5748872EFA" modified="2016-11-30" version="1">MDVMKPDEVKVPLKDGTEKCMKEHGEKVEGNNDPKCMTFMEVGQCVHDVFFDVCID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIY2</accession>
    <name>A0A1D2MIY2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001103">
        <property type="protein sequence ID" value="ODM92987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIY2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="17002" checksum="2912CC3A9A1CD6B3" modified="2016-11-30" version="1">MALTKLFKPGSREFSQIVRSLRQCLQVLNGLDQSKTDPCDNNGWASVFECLDTASGCMPISRGQLMGCYDNDNPATWKVRSGNSIRATAHCCEHRIMNCYKYDYQGNEQKVCQVESNERKEQLKQCCDTSHLVSYIPVDPRDHGSTVLSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ24</accession>
    <name>A0A1D2MJ24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5-oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001101">
        <property type="protein sequence ID" value="ODM93006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ24"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ24"/>
    <dbReference type="OMA" id="TDCNVML"/>
    <dbReference type="OrthoDB" id="3643at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF2">
        <property type="entry name" value="5-OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="4">
        <location>
            <begin position="53"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="289"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="3">
        <location>
            <begin position="715"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="3">
        <location>
            <begin position="817"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="3">
        <location>
            <begin position="1044"/>
            <end position="1229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1230" mass="134899" checksum="4B0DF22647B74A60" modified="2016-11-30" version="1">MRERNGVGLRRLPMFPVSVAGDKEERIKRVCRFFRAQKQRRPEENMSKTGKFRFSIDRGGTFTDVFAQCPSGSVRTYKLLSKHTCYQDAPTEGIRRIIEMESGKTLQPDAPIDSSLIESIRMGTTVATNALLERKGERTGLLITKGFRDLLHIGNQARPNIFDLSIAIPEHLYCEVVEVDERVVLESDQCELKLKQGDSVSLPSHSVNVVRKLDLEVLEGDLKKLLEKDVRSIAVVLMHSWVVRQPREADRAARLGPRVQARQHLQLCHEDGSAGAGSAVGPCRRGRGYARTVFDKYGIPVIGFDMGGTSTDVSRFDGEFIHTFESVTAGVPLQCPQLDIQTVAAGGGSILTFSSGIYNVGPESAGANPGPVAYDHGGELLTITDANLILNRLLPSRFPKIFGPTHDSELNATKTLEKFKQLRSKINAFNEAHGLEPLNVEEIALGFIRVANETMARPIRNITQGKGFDPSTHMLACFGGAGGQHACAIAKSLGIKLVSVPRYAGILSAVGIFLADVVIEENEPVGLLITDDNYSRTNELVEHRFKVICEELGAKLKSEGNYSELKFEKYLNIRYSGTDCALMVKDSPPLKNFTARFVDEYSRQFGFQLQRELVLDDIRVRAVGVNEIIHENEKQEEISTLPLGTINAYFNTGSHETPYVACVPGIYRGPCLILDNLSTIVVEPGWVATVSDKDVKLEFEVLKNENEETRPIVLDSIMLSIFSHRFMSIAEQMGRILQRTSVSTNIKERLDFSCAIFGPDGGLVSNAPHIPVHPGPCRRLCSISYALLRGVAASSVGVMGFLLVRCCCPGMDCDPSSPIFFVANRGHHADIGGITPGSMPPNSKSIHEEGAVFKSFKLVREGNFMEEQLVAELMKPGEYPGSSGTRNLSDNLSDLRAQVAANQKVGHPAPPLPDIGVLAPVRPEVHAVHPGERGGGGSRNAEDSGGKLLPKIIRLRVHGRRKRNSANSEHKQARGLCNVRLHGNNLPGDWELQRSESNYVISSDLLPPVPRRKGHPAEPRVLKANTHNHPGRKHPPPLRGRCSGWGNVLTSQRVVDVILKAFEACAASQGCMNNITFGDNTLGYYETVAGGAGAGPTWEGRSGVHTHMTNTRITDPEILELRYPVLLHHFSLEKHSGGVGKFRGGDGVRREILFRKHMKLSVLTERRVFTPYGLKEGGDGKRGRNLLVKNAWRDQSKGKIINLGGKTSVDVEPGDMFTLISPGGGAWGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJL1</accession>
    <name>A0A1D2MJL1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-aminoadipate-semialdehyde dehydrogenase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13473</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001044">
        <property type="protein sequence ID" value="ODM93217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJL1"/>
    <dbReference type="STRING" id="48709.A0A1D2MJL1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF1">
        <property type="entry name" value="L-2-AMINOADIPATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="3">
        <location>
            <begin position="90"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="459" mass="52471" checksum="2C30316FDBFC8E48" modified="2016-11-30" version="1">MISLFRAFPNGVSVCSQILTRRSVHHNAGVKFQGSVVTRRREKFETNNHWTSENVNELIREDSELPGHIRAKSNQFIKEIGDTKTVLLLGSTGTMGPYFLETLCNMEQISNVVCLMRGNNDVVYRNLKSWQHVKTENLHKVTCVNGNVAFPHLGMSDRLWDSLTNSVDAVINCAARIHHTEIYTNNDSNRDARAVNVGGIKNILEFACENRLKHVFHAGTFLAASKVREGVIAEGWPEDVGDFDFATSLAYPITKFVSEMLFKEAAKRGIPCKVFRFPIVTGNSKTGKFCLNNNHVMLRYISILTNGAIPSSPMPMPMLPIDQCAEISMKIFFHDKGGQSDLYNITHPNVDIDQEFVQVAKRFGKRVSLVDDEEFAKSLERDLERGTNFGAFKNYYVKDQFWKKYRCHLPLFKFWRPGNDGYFVSKKLETLMPDIYDPEERTMDYVYKDLKFAKNNGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJU3</accession>
    <name>A0A1D2MJU3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase III subunit RPC4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001041">
        <property type="protein sequence ID" value="ODM93238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJU3"/>
    <dbReference type="STRING" id="48709.A0A1D2MJU3"/>
    <dbReference type="OrthoDB" id="5836119at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="339" mass="37551" checksum="9FBD9F395051E896" modified="2016-11-30" version="1">MQQIVLEVEEEGEEGIGVAEVVVNKEVNWSNPSQFFLMGWAIPWMRKGARLHNIGVVRWGSRYKSATEGGAARMSSLNRNTLNTLIKEEDAESDKKIFGTEKFDAEDEEDVNPANSNVPVILPLSNYIPEYFMEPAALAIDSPPITTLPETADLPTPSTSSEPSTLIPVVKIKQEKPDEDETVSLKVKEELDSEDAIKRNERLLSTMHLESTAFASSFRSTPPEGTLVYFQLPDELPVLEGSVRESVDQQGSSKNTAQMVGDIDDLPEGFIGRLQIMSSGRTRFILGENSFDVDSGRPVGFRQELYAVDEDSATLTNLGPIHNKFVITPDIEYLIEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML06</accession>
    <name>A0A1D2ML06_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proline dehydrogenase</fullName>
            <ecNumber evidence="5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13138</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000958">
        <property type="protein sequence ID" value="ODM93544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML06"/>
    <dbReference type="STRING" id="48709.A0A1D2ML06"/>
    <dbReference type="OMA" id="EGMLMCL"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="374"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="580" mass="66924" checksum="E75C0AC41CF401EF" modified="2016-11-30" version="1">MAFFHHVFHQQRRLFQEFVARYPQLWLRRSSSKPSAIPPPPASGTETIERDKLDLSFTDARQAYRSKSTLEILRAWTVLRLCSVNFLVENNPKLMKLGQRILGKFLFRKMMEMSFYGHFVAGPDQIAIQPKLQRLREFGVKAILDYSVEEDLSEEAAKKKEAETESAVPIPAAELPVGINPMKQYHSSEEFADRRKKAVARTYFYLDEAQCERNMETFLQSIEAVSIATAGTGFAAIKLTALGRPQLLMQLSEAIARVHRYVGAVTGRKGYITQQGAKPEDFQRALDRAAKLDPTVQHWLDGMTYDSTGLIHILPWKGLVEAQRNIGEAMKVPDLKTGQLKSIMPKPLSKREEEMFKNMMRRLHKIFNRASDLEVRCYLRNARRYLSADMEQAKRQGFHFGAKLVRGAYMEQERQRAAGMGYPDPINENFEKTTEMYHNCVEEGMRRIVEWKKEGKPRMVQLMAATHNEDTVKFVIQKMRDYGIRRVDRVISFGQLYGMCDQVSFPLGQSGYSAYKYVPYGPVAEVLPYLSRRAQENRGFVGKTKKEMGMLRKEFFRRVLKGQLFYRPKGRYQALKDVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML33</accession>
    <name>A0A1D2ML33_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="8">HIU hydrolase</shortName>
            <shortName evidence="8">HIUHase</shortName>
            <ecNumber evidence="8">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_12973</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000930">
        <property type="protein sequence ID" value="ODM93710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML33"/>
    <dbReference type="STRING" id="48709.A0A1D2ML33"/>
    <dbReference type="OMA" id="RFSFSTY"/>
    <dbReference type="OrthoDB" id="10265230at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM93710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="12162" checksum="411FA0C92CF5B641" modified="2016-11-30" version="1">MASNPLTCHVLDTSTGKPAVGIPVTLSKFENDELTDSDGRVGNLISSEEFTPSRYKLTFSITLAYYEGRGEKTFYPYIDVVFEIERPEEHYHVPILLSAYGYPTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLA3</accession>
    <name>A0A1D2MLA3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heart-and neural crest derivatives-expressed protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12847</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000904">
        <property type="protein sequence ID" value="ODM93839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLA3"/>
    <dbReference type="STRING" id="48709.A0A1D2MLA3"/>
    <dbReference type="OrthoDB" id="10055449at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11466">
        <property type="entry name" value="bHLH_TS_HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000010">
        <property type="entry name" value="Scleraxis bHLH transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050283">
        <property type="entry name" value="E-box_TF_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349:SF68">
        <property type="entry name" value="FI14601P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="142"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="265" mass="29835" checksum="3CF602F48E995DB3" modified="2016-11-30" version="1">MNCQENTPRNSRYSEFSSDGWCAPDDYYNENYLPNDSHVAMSSGQQPPYNNYYEYQGVNASSSAPQSQPVSSFPQKRSPSEEMYSSASNRQECYEPKSPSSASSSWNFHSFYQKNPSPSNSIIGSPGNPGSDSSKLPRPSFKRRTTANKKERRRTQSINNAFAELRDCIPNVPADTKLSKIKTLRLATSYIAYLSEVLTGDDPLRTPQAFTAEISKKMGRGDEKRRKELLMQELAGAGMKRSDDSRKSKGRTGWPQHVWALELQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLS5</accession>
    <name>A0A1D2MLS5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">procollagen-lysine 5-dioxygenase</fullName>
            <ecNumber evidence="3">1.14.11.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12830</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl-[collagen] + 2-oxoglutarate + O2 = (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:16569"/>
            <dbReference type="Rhea" id="RHEA-COMP:12751"/>
            <dbReference type="Rhea" id="RHEA-COMP:12752"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:133442"/>
            <dbReference type="EC" id="1.14.11.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.4" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000902">
        <property type="protein sequence ID" value="ODM93852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLS5"/>
    <dbReference type="STRING" id="48709.A0A1D2MLS5"/>
    <dbReference type="OMA" id="TDVACNH"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008475">
        <property type="term" value="F:procollagen-lysine 5-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050757">
        <property type="entry name" value="Collagen_mod_GT25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057589">
        <property type="entry name" value="GT_PLOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730:SF45">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25342">
        <property type="entry name" value="GT_PLOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 14" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="13">
        <location>
            <begin position="692"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM93852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="784" mass="89491" checksum="13163A644EC3F08A" modified="2016-11-30" version="1" fragment="single">MTVFRLIRRNNSATVTMYVAAIVLIHCLLGAVTGVAGEESSDANPENLVVLTVATEWTESLQRYLRSGRVNGFDVKVLGLGQKWEGGDVRVGPGGGQKVNLVKAELEKLVQEKGSNDDLTVLFTDSYDVLLLGNGEQILKQFKMSNARILFGAEGFCWPDESLANEYPEVHRGKRYLNSGGYIGYASSLLKLLKSKEIENKDDDQLYFTKLFLDESVRTDLKIKLDTKSSIFHNLNGATAELEMQFVSGVATLLNTQQNTHPLVLHGNGPTKHILNSYGNYLANNWNEESGCASCWEDMISLTEIGEEKLPVVLLGIFIEKPIPFMEEFFGKIQHMDYPKKKIHLFIHNDAVYHEKIVTEFLANFSSEYASVKTIVPTDKTKEWHARNLAIDVAIKKNADFFFSVDGEAHLDNPFTLKLLIEQNRGIIAPLLVRPYKAWSNFWGALSSEGFYARSNDYMELVKGERRGLWNIPFISAVYLVNKTIFQNEKTKPSYINNLLDADMAFCLNNRNRDVFMFVSNRVDWGHLINSDNFETTHLHNELFQLFDNRWDWELRYLHSNWSKALDANLTLTDMMADKEMMPCPDVFWFPVVTPRYCTEKIEEMENYGKWSDGSNYDSRLDGGYENVPTVDIHMNQVGMEAQGLSFSDSMLSHFKPKMTSVQKRAMMNIQRLTNICFKLACKTNGSSSYPPFASMNFVVRYKPDEQRELKPHHDTSTYTINIALNTPHKDYEGGGCRFTRYNCSVRDTKLGYMIMHPGKLTHQHEGLRIFKGTRYIMVSFVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MML3</accession>
    <name>A0A1D2MML3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tight junction protein ZO-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000858">
        <property type="protein sequence ID" value="ODM94111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MML3"/>
    <dbReference type="STRING" id="48709.A0A1D2MML3"/>
    <dbReference type="OMA" id="FHISNMI"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000906">
        <property type="entry name" value="ZU5_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00791">
        <property type="entry name" value="ZU5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51145">
        <property type="entry name" value="ZU5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZU5" evidence="2">
        <location>
            <begin position="86"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="223" mass="25114" checksum="B0FDF4324DA3469D" modified="2016-11-30" version="1">MIDRTKKPSSTGFYPVSPQHLTSTKPVTPVKPVPPPKPKLPSLPKYQPQNQVQGSSSMDESPDDTGQTYLNIPMNSKAAIRAANDTITSGYFDWRGGRLVQKHTFGSQIPIEVFIPERAIPIGETVNVWFQIIDYNVRDDPNNPQKMLSPLVKFGPENYRFQIPVEIRIPQYSAASAMNDNLLAKVLMNNQSEYWTKIDIQNGNYDNEFGSEVKVVSLTVQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNT1</accession>
    <name>A0A1D2MNT1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ets DNA-binding protein pokkuri</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12022</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the ETS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000773">
        <property type="protein sequence ID" value="ODM94663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNT1"/>
    <dbReference type="STRING" id="48709.A0A1D2MNT1"/>
    <dbReference type="OrthoDB" id="6408625at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000516">
        <property type="entry name" value="ets DNA-binding protein pokkuri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046328">
        <property type="entry name" value="ETS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003118">
        <property type="entry name" value="Pointed_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849:SF201">
        <property type="entry name" value="ETS DNA-BINDING PROTEIN POKKURI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00178">
        <property type="entry name" value="Ets"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00454">
        <property type="entry name" value="ETSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00413">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00345">
        <property type="entry name" value="ETS_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00346">
        <property type="entry name" value="ETS_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51433">
        <property type="entry name" value="PNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNT" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="ETS" evidence="5">
        <location>
            <begin position="227"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="327"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="383"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="419"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="487"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="529" mass="56940" checksum="25634B87F035D1F2" modified="2016-11-30" version="1">MLGKALCLLTKADLESRVPCSGDVIHNSLQLLMTSGDSPLTPHTPSSLRIPQLGVNGKGVTWSITDLQQYAAAQQQQATTSVTLSPAPSLDGQAGSPQDHGNGQTSQHLSSASSSTGSGGPPSDDSEYDSVGESPERSPPIQSMSPPPSHSNSTNNHSANGGHHHHHSHHHSNSTNGASNGASTIAANSNGNGAANVTAKSSFSPGSKLTNGAAGTAEAGEYNNNGRLLWDFLQQLLNDPAQRYSNFIAWKNVDTGIFKIVDPPGLARLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPGELKSIKNISMLRHQQNSPMSLSVKSDTTSYGNENGSNGNDYDSKYSLLSHHHQQQQHNSPVSLTVKSESMGYGRESASDDYESKLSMLGHRQQSSPVSLTTKNCSASPSSTSSTSSIGAPGGDSYENGDYDSINGHPQESPMSLTTKSSPSHHHHQDNDGVDSRGHRPKPQLSPVSLTVKSEPTTAFITADDDYEDVPTDLSMETERDRQSKEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP60</accession>
    <name>A0A1D2MP60_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000748">
        <property type="protein sequence ID" value="ODM94803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP60"/>
    <dbReference type="STRING" id="48709.A0A1D2MP60"/>
    <dbReference type="OrthoDB" id="6682367at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="85"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="270" mass="30495" checksum="398AA8B187A3B695" modified="2016-11-30" version="1">MSCIPTPVEQAKIAQLKSTLEEHLKATPSNNAKVRAELQKIVADPDFLFKYLRGRKLNVTRAFETILKYAEVKCITFPEYFPAQVPDYVRHCIESKILNLITKKDKLGRTYVVVDTTKFDDSIVTVIEATNALRYIFEALMNYPDFLDNGVVIMENAGGIKMSHGKGAPTVAGFYTNFWVRYEKFSKAFPGKLKELIYFNAPFYGKGLFAVGKPLFKIKAADRVFVSSGLTELHKRVPLDVIPKCYGGTLPDEVAYMPTEKLLAMTLKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPE1</accession>
    <name>A0A1D2MPE1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Integrin alpha-PS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_11716</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the integrin alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000728">
        <property type="protein sequence ID" value="ODM94960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPE1"/>
    <dbReference type="STRING" id="48709.A0A1D2MPE1"/>
    <dbReference type="OMA" id="FPLRACF"/>
    <dbReference type="OrthoDB" id="5317514at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033627">
        <property type="term" value="P:cell adhesion mediated by integrin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007157">
        <property type="term" value="P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.930">
        <property type="entry name" value="Bicelle-embedded integrin alpha(iib) transmembrane segment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1460">
        <property type="entry name" value="Integrin domains. Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1510">
        <property type="entry name" value="ntegrin, alpha v. Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1530">
        <property type="entry name" value="ntegrin, alpha v. Chain A, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000413">
        <property type="entry name" value="Integrin_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018184">
        <property type="entry name" value="Integrin_alpha_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013649">
        <property type="entry name" value="Integrin_alpha_Ig-like_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048285">
        <property type="entry name" value="Integrin_alpha_Ig-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048286">
        <property type="entry name" value="Integrin_alpha_Ig-like_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032695">
        <property type="entry name" value="Integrin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220">
        <property type="entry name" value="INTEGRIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220:SF133">
        <property type="entry name" value="INTEGRIN ALPHA-PS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08441">
        <property type="entry name" value="Integrin_A_Ig_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20805">
        <property type="entry name" value="Integrin_A_Ig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20806">
        <property type="entry name" value="Integrin_A_Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01185">
        <property type="entry name" value="INTEGRINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69179">
        <property type="entry name" value="Integrin domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00242">
        <property type="entry name" value="INTEGRIN_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13 18" id="KW-0401">Integrin</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1034"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="12">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="12">
        <location>
            <begin position="83"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="12">
        <location>
            <begin position="145"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha first immunoglubulin-like" evidence="15">
        <location>
            <begin position="192"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha second immunoglobulin-like" evidence="16">
        <location>
            <begin position="348"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha third immunoglobulin-like" evidence="17">
        <location>
            <begin position="500"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha third immunoglobulin-like" evidence="17">
        <location>
            <begin position="927"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="601"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="636"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="737"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="834"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="898"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="667"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="682"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="768"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM94960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1078" mass="118237" checksum="5CFCFDC20EDA5980" modified="2016-11-30" version="1">MTFPTCCVVVIYSSDLLHIQNITGDQIGAYFGYTLTVLDIDGDGLDDLVIGAPMYTDFDDPAMKIETGRVYVIYQSRQHHFGKFESIDGTAHKGRFGLSLASCGDMNKDGFNDFAVGAPYDGIYGRGAVYIYHGSSTGVRKEYTQVIYGEELSHTVSTFGFSLSGGKDLDGNQYPDLIVGAYESDVVAYFRSKPVVRVKSKLSFPQIANKQINLDEKECTLRDRTSVTCTQLSICMEYDGVGADDVIDFNVQYTLDAKKPKDSRMFFLNHEGRNVLNETVRLTKKKQVCSSQQVYLRPQIRDKLTSLEAELRYSMRESRYHERRELPPVIDITTSSVEKESISIQKNCGSDNICVPNLIVKVNQSDRSFLMGSTKRIWVEVEVANNGEDSYETMLYMSVPQGLSYVNFDRLDTSKDVPILCSAPTPSTNNTLRCDIGNPLPFHSKARLRVFFQPRYGSEIKSSYDFLVEANSTNPEDIHKRGDNLMPVRFPIRVQTDMKVFGVSDPQPVRHNATLWKKNEEKDKESDIGPEVTHIYELKCEGPSDIEEAEVRILWPSYTLAGQHFVYLLEQPLVDGPAECDHVDDVNPLALTLSRKSKWQSRRVEQHHEEHHHQIITTGGGIEMDLDTEEALLRREQQGGYSRSSSSSSGGFRTSSSGVVHGGTGISGENTYGSSSSSTGGVRTGGGTISTGNVHGQGGYGTISRHSGGAGTYIAEVRPGAAGSGFLFWGERVSSGSGIHSGGERVSSGSGIYSGGERVSSGSGIYSGGERVSSSSSGSGSYSGGERVSSSSSGSGSYTGDTYSRSGGGYVDGGGAAGSSGSYSGGTYSRTGGGYVDGDERYSGGERYGVGGSGYQNRNSSSQHEYRREHSLGGGTGSSGGYSSAYNYSRTISRTEYSRAGTGAGSGSSLSTGDGDEYQESYFNNRNRRHKRASEDDPEKEMGCGPTRCTRIRCHIKHFPKNSSVIFMLRGRIFSDTLVQEFHGDSVNVSSKLVTWVTKLPYNVDPTYLRYRKYEIDTTIEELPDLSVPAPIPWWVYFLAALAGVLLLLLIVYIFYKCGFFKRRRRPSGPEGQPLNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQD5</accession>
    <name>A0A1D2MQD5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000709">
        <property type="protein sequence ID" value="ODM95112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQD5"/>
    <dbReference type="OMA" id="GPFCTSA"/>
    <dbReference type="OrthoDB" id="191150at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF9">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="28265" checksum="FBDE4A003651B6AA" modified="2016-11-30" version="1">MGDSDDQDEPRSTGSRNKVAPMVGAEIPPGLAYLAPLGMIIVKQQHELAELICGCECQNSYLIKDQFGRDIFQAKEDSCCMTRQCCGPDRCFEMTIKNFQGAEVIHLQRPLRCRSCLFCCCLQKINVFSPPGNLIGSVKQTCTLCKPNFNVRNEMGEVVFKIKGPCCTSSCCGNDVSFNLFTPDGDTQVGRIAKTWGGILSEAFTDADNFGITFPVDLDVRMKATLIGACMLIDYMFFERGGGEAAGATGAAAGFLSAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQK3</accession>
    <name>A0A1D2MQK3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="6">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EIF6</name>
        <name evidence="7" type="ORF">Ocin01_11634</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <text evidence="6">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQK3"/>
    <dbReference type="STRING" id="48709.A0A1D2MQK3"/>
    <dbReference type="OMA" id="WCAFCGM"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00062592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="27277" checksum="D75731540B9236ED" modified="2016-11-30" version="1">MAVRVQFENNNEVGVFSKLTNSYCLVAMGGSENFYSMFESELSEVIPVVHTSVAGCRIIGRMTVGNRHGLLVPNSTTDQELQHLRNALPDSVKIQRVEEKLSALGNVITCNDYVALVHPDLDRETEEILQDTLKVEVFRQSVATNVLVGSYCLFSNQGGIVHPKTPSQEQDELSSLLQVPLVAGSVNRGSELVGAGAVVNDWSLFCGMDTTATELSVLESIFRLNAGAIGGPGSSASSVQGENMRNVLIESMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS88</accession>
    <name>A0A1D2MS88_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone H3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Putative variant histone H3 which may replace conventional H3 in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000623">
        <property type="protein sequence ID" value="ODM95761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS88"/>
    <dbReference type="STRING" id="48709.A0A1D2MS88"/>
    <dbReference type="OrthoDB" id="10256681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000001">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="6">
        <location>
            <begin position="44"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00059206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="18187" checksum="E9545B6C34E8A98F" modified="2016-11-30" version="1">MARTKQTARKSTGGKPPRPRLVTKAARKTALPAGGVKKPHRYRPGTVALREIRRYQQSTELLLRKLPFQRLVREIAMDFKTDLRFQSSSVMALQEASEAYMIGLLEDTNLCAIHAEGHPISQTHPWRTNLNNDRTLTSSHNPTALLRATTVFKEQTIHYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT14</accession>
    <name>A0A1D2MT14_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adenylate kinase isoenzyme 6 homolog</fullName>
            <shortName evidence="10">AK6</shortName>
            <ecNumber evidence="10">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Dual activity adenylate kinase/ATPase</fullName>
            <shortName evidence="10">AK/ATPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10650</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer and homodimer. Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate kinase family. AK6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000591">
        <property type="protein sequence ID" value="ODM96041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT14"/>
    <dbReference type="STRING" id="48709.A0A1D2MT14"/>
    <dbReference type="OMA" id="QCEIFGT"/>
    <dbReference type="OrthoDB" id="5970722at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000372">
        <property type="entry name" value="Adenylate kinase isoenzyme 6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00039">
        <property type="entry name" value="Adenylate_kinase_AK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020618">
        <property type="entry name" value="Adenyl_kinase_AK6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595:SF0">
        <property type="entry name" value="ADENYLATE KINASE ISOENZYME 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595">
        <property type="entry name" value="POS9-ACTIVATING FACTOR FAP7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13238">
        <property type="entry name" value="AAA_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="10">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="10">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="20044" checksum="3A84401E80780CD9" modified="2016-11-30" version="1">MRSLPNILVAGTPGTGKSTLAQQIAEETGLEWLDVSQIAKENKCLEGYDSTYGCHVLNEEKLLDEIEDRMEEGGKVVDYHGCDFFPKRWFDIIFVLRTDNTVLYDRLIGRGYSGKKLEDNVQCEIFQTILDEARESYSPEIVFELPSNVSSDMESNLEKITQWVETYKQNVIQTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTU7</accession>
    <name>A0A1D2MTU7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000546">
        <property type="protein sequence ID" value="ODM96362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTU7"/>
    <dbReference type="STRING" id="48709.A0A1D2MTU7"/>
    <dbReference type="OMA" id="IIDISYV"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF176">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="171"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="304" mass="34286" checksum="99C6BF0AE6DBD3F6" modified="2016-11-30" version="1" fragment="single">MSLERFEILLDDGIKEYRPGQIISGKIVIKANEEIKCEGLTLKFKGHAYVRFTSGTENDEDTFTDSEVFFEFKEQLMGDGKNEIRISPGHEHVYEFTFQIPLQPLPANFKKLHGKVEYFLKGVVKRSLWKLNITTLQSITILPELDQDLVLEAALPSEIKTSKTFGFMCCTSGPLYLNVRVPRRVCVPGETILFEVEVNNMSRNRIADLSAQIFQKVYLTGKHLKREKTSTSHASFNEIRRGHGVVEGDCDTWCDELLVPLVPPTKLGGGCKFIDVQYFILVTAHVADLCAINPKALCPILIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUI1</accession>
    <name>A0A1D2MUI1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000510">
        <property type="protein sequence ID" value="ODM96703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUI1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="19205" checksum="4A69991AF86BC66F" modified="2016-11-30" version="1">MSCLTGVYVFIALVELVSGLVASVWTAFYNDKEVDEWAYGIFAFYLAFAHFLLYASGRQTFCRGHFNSDHSTALNVICWMSSVITIFLFTGLYYYNKKVLGHKTQNKLMIYPFIAYIVAIALFFVVNVAVSMEKDIRTQKTYRSLVNPAPGSIDASLARMVEHVRRNPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV71</accession>
    <name>A0A1D2MV71_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">allantoinase</fullName>
            <ecNumber evidence="6">3.5.2.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09862</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-allantoin + H2O = allantoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17029"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
            <dbReference type="EC" id="3.5.2.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.5" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000500">
        <property type="protein sequence ID" value="ODM96822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV71"/>
    <dbReference type="STRING" id="48709.A0A1D2MV71"/>
    <dbReference type="OMA" id="SRLHVCH"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="UniPathway" id="UPA00395">
        <property type="reaction ID" value="UER00653"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000032">
        <property type="entry name" value="Allantoinase Dal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017593">
        <property type="entry name" value="Allantoinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03178">
        <property type="entry name" value="allantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF2">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="10">
        <location>
            <begin position="60"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="454" mass="50009" checksum="C55F6C6D181A6F23" modified="2016-11-30" version="1">MQFLGKNLEGIYGERVLIGDELVPATIIISNGKITEIQRHVSGYNFCSSDDSVFNAGNNVVMPGIFDSHVHINEPGRTEWEGFFTATKAALAGGITTIIDMPLNSIPPTTTLENLEVKLKAANGKCHTDLGFWGGVVPGSTDSLKPMINKGVIGFKCFLIHSGVDEFPCVNEDEVDRALNAIKGTGAVLAFHAETDCGSCTTDNADPNQYSSFLASRPDEMELDAIKMVDRLCRKHKNVRCHIVHLSTARALPIISKLKEDGFPITVESCPHYLTLNPQEISDKQTQFKCCPPIRDSNNQNELWNGLKTGVIDMIVSDHSPCTADLKQPGEKNFMEAWGGISSVQFGLSIIWSQAEARGFNIPTLSRWMSQEPARLAGMSNVKGKLDINYDADIVIWNDEETFQVTDDIILYRNKITPYKGKLLKGKVLATILRGQIVYAENNFSNISGRLLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVS5</accession>
    <name>A0A1D2MVS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000492">
        <property type="protein sequence ID" value="ODM96904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVS5"/>
    <dbReference type="OMA" id="FICIPAD"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="574" mass="65851" checksum="0E4564F1931EBA9B" modified="2016-11-30" version="1">MEALRELPLLSRERRRTSAPNPFLIPMITDQILTYSNYATRKNCRLVCADWERQASKFLNIKKNPYTVRIPSEIELRRCNADHNDIDDADEQNCRFYDFICIPADCNYLIVPYNIGLNFYPIVYQILLNSGQQLRFLELRNAHWTLAQLRDVLYKLAPKLEELVLAEDFVLPKVDPSSSRVLVEFDPKTHSIRQLPRLKSIKLELQDENLQNLANLQFLQELFTVAPNVKCIRGSTKAFTENAPPHTTIFSSLLFRSIAESQALISSKALTYLDINVELRNADIDLLEAANFPLHTFHLTLDMLASSVKVDGLLSGLRGTLRRLKITHRGCIRTSPNLVNLQNLEYFAIHGYETEIRKDPRRGDSIVLDQALYFVFRFVPLCLFPAFVEGCEALQKIVELRLCHTFYARKDIYNLKSLFPCLKKLRVSFLDDDTLGRICQDYPHLEELGAMDGKFSDMSITGISPQIQEIFQNGVTNEVKDQNLRELPSITDLKYLRVLELGSKNVTDFGIINGIAICTHLKELQLDCPNISDVSLQKIVQKLDLDRLNVKSGSFTERVVQQTRGRLSRKSFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWF8</accession>
    <name>A0A1D2MWF8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000456">
        <property type="protein sequence ID" value="ODM97292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWF8"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="38"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="15319" checksum="FEDBACB36D88D3E2" modified="2016-11-30" version="1">MQKALVAGFGFYAFVVICTTSAISLHRDFIELPVVRTPPSCMLGRNHMEGDIPDPFNCHLFYTCAPGEEGGTTAQNRTCPSNLYFSFRTCRCEFDISGCCIGCLNAEFFNCTTIYDPSIRDEESTETIPILSQSNSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWG4</accession>
    <name>A0A1D2MWG4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000447">
        <property type="protein sequence ID" value="ODM97399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWG4"/>
    <dbReference type="STRING" id="48709.A0A1D2MWG4"/>
    <dbReference type="OMA" id="ENEVIHI"/>
    <dbReference type="OrthoDB" id="348005at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052004">
        <property type="entry name" value="Dynein_assembly_factor_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46492">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 4, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46492:SF1">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="4"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="533"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="589" mass="67054" checksum="170E21EACA1A03C3" modified="2016-11-30" version="1">MMPIIIKDFEWSENAEWVFITLDMKGVKTGSIDIVSSPTYLKIHWSPFIFEVFLKHKVDDDLGECTFDKSCGKVSLRLKKGECGVSWGQLENKELTKEEKSAKRAAAIEISHQRHEQEKKARQKRQFNRKQASVQDQIRLDSEAKERITQIKNFESQKAVNELNEWASTADLNPNNGCSFVEELSVEEVDHNSRSIISAFAHQHSAANDSGGGRFTECSSPADQNPARDELTPSTKGTFETDAAPEEPSVEKDRRQNNNRIWTEDEVNELPVGVERSQQHYSHQHHQGEPNERSLSNGTSDGNPAISLSAERMSSPMERKEESESGRNICSTGLGPQVAEKSLGLPSRLRDQEHSPRDESRGTPVENRAETEKCDAKNRHSDRRTVQVAKPSSKIENEVIHIRPTVCISVNFTPREFPTPCRESLMVEEQEWLKKQAEARRLSGFVDEDLRPEERNPQWLLDKGLSLMRAESYLGAISAFSLGIRLAPKMPELYVERAGAHLAVKNYHRTVEDCSQALELLTPKVKANEGDRLKCHIRRGDAFRNLEMWEDALTDYKEAIRLKPMSEELISVRDEIQMVLERENKEKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWW9</accession>
    <name>A0A1D2MWW9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vesicle tethering protein Uso1/P115-like head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_09255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000444">
        <property type="protein sequence ID" value="ODM97421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWW9"/>
    <dbReference type="STRING" id="48709.A0A1D2MWW9"/>
    <dbReference type="OMA" id="GQETFCN"/>
    <dbReference type="OrthoDB" id="198977at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048211">
        <property type="term" value="P:Golgi vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045056">
        <property type="term" value="P:transcytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041209">
        <property type="entry name" value="P115_Arm_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18770">
        <property type="entry name" value="Arm_vescicular"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="6">
        <location>
            <begin position="352"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="703"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM97421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="866" mass="96882" checksum="D917FB58244C4EEC" modified="2016-11-30" version="1">MELFKGVWGGQQTTTTNGRSVQDQQTGAETVERLVERLLNSTLLTDRRDACRALKALSKKYRVEVGAQGMDAILTSLESDRIDSELVSYALECLLNVTSPELLEDEDSSLSSMGEQFTEIIAKKPDNLTMLVSFMEEYDFRIRLPVIRLVTNLLTNKPKDVQEILLVSPMGISKIMDLLSDSREVVRNDAILLLVALTKNNANIQKIIAFENGFDRILQIIQEEGYSDGGPVVEDSLQLFLNLLRSNTSNQTFFREGSYIKKLVPFFTLPDSDGDLGWPTQKVSNFYHMLQIVRTLTSPSNPSHITLSCQKVIKGCGILECLCEIVMANGIPSETLAEAIATVGEAIRGCLDNQEYFGSVVAPSEPPRPVLVILLMGLINERQPLSLRCSVLYCIQCHFYKNEKSQEDVIKSLLPSTGDAVNTLTAGQLLCGGLFSKDISNNWFSSVALSHTIMGNMKQKENLLKVQFSLKANSGPVTLMNYILMSLQQSTKLQMRTAFLQFLSIWLEGCPNAVAQFLSNPTSVPYLITQITSAESDEKEALVRGLASFMMGICLFFNPNTVTAFTKESMVQLINNRIGMETLSDALGQISKSELYIHSLKHPQLGAKHSSDLIFDHYFCIMFKKYESLILQQLNDPGGSHVHVDSSSQDFSKLGHMVNNHQSPTDVISRYKEVIRTQDEAIATLKKDVYSLQSSNSVSSSTIEELTSEVLQLKNQLVLANAQRATTELSSEKNSQAHIAEYQTILQRKDQQLREMEDRLRGLESGIQMKNPIQEELISKLEEENKVLVDEVEKMKKDQEELLELLAEQDSRILKFKMQLQSLGVQIEEDDETAEEPQNLDGNETVDLATNVFNGGEHSDNENFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWY9</accession>
    <name>A0A1D2MWY9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09126</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000432">
        <property type="protein sequence ID" value="ODM97560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWY9"/>
    <dbReference type="STRING" id="48709.A0A1D2MWY9"/>
    <dbReference type="OMA" id="MAYNISN"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="33795" checksum="7776CE46DC36C359" modified="2016-11-30" version="1">MAYNISNDPFYSDLYFKRAFGYTFLENPYFHGFEFEKIGFTGWQEFMIENWKLAIYASVFYVITIFGLQRVMKNRPAFDLRKCLFVWNLAIGLASLVGFIRVFPAFLTVLSEQNGFYNSICVKKGLDIPSAYWAIVFACSKFLELGDTVFIVLRKRPLVFLQWYHHLVTLMVTWITAPLVEPIVRWYAVLNAFVHSFMYLYFALRAISVKIPSYVANFITTIQFSQMLVGFVVNMASWYLQHNGYGCVRYPLSINVFGFVYGTFILLFGKLFYDSVIKSGRKLKQKTKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXG3</accession>
    <name>A0A1D2MXG3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08964</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MPI phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000417">
        <property type="protein sequence ID" value="ODM97727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXG3"/>
    <dbReference type="STRING" id="48709.A0A1D2MXG3"/>
    <dbReference type="OMA" id="IPMLHED"/>
    <dbReference type="OrthoDB" id="26523at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000086">
        <property type="term" value="P:G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110032">
        <property type="term" value="P:positive regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000021">
        <property type="entry name" value="M-phase inducer phosphatase cdc-25.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000751">
        <property type="entry name" value="MPI_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF17">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00716">
        <property type="entry name" value="MPIPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="10">
        <location>
            <begin position="263"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="64"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="414" mass="46358" checksum="8D31EB16AC48FC1E" modified="2016-11-30" version="1">MDGKQDAAIKEDNAKPDNSIAQHPTPPSSSFTAFKLKTYNELRVDENNLPSSSIAELWQKPFHNSFASSKTPKARLKGRLHQNSSSRRNLLPPTKLSFDNMDSSESPTSNVGKTGIRRSSSYPESGTSCNSNFGSPSQNAKRLKTHDENSPADTNPSPNENSPYNDLVGSDSSQNSTKTSTSLTPVVRNLFLGKKSHSDSGLSSCNIKTALEKIESNPNLIGDGTRSHQLPVKTDGKHRDLKEIDGETLADLIARKDAGENLNFRIIDCRYPYEYIGGHIKGAVNLYTKNQVYMELLEQKTSSTCSSSCSKENEDPSATEILIYHCEFSSKRAPSLCHYVRNVDRAVNSYPNLYYPEMYVLHGGYQEFFLKFDHLCDPQNYIRMDDPKYAEEYRKFKSESKLGTKSKDDQLVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYD4</accession>
    <name>A0A1D2MYD4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcriptional adapter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_08720</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000393">
        <property type="protein sequence ID" value="ODM97951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYD4"/>
    <dbReference type="STRING" id="48709.A0A1D2MYD4"/>
    <dbReference type="OMA" id="HMKEEYP"/>
    <dbReference type="OrthoDB" id="270417at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070461">
        <property type="term" value="C:SAGA-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016827">
        <property type="entry name" value="Ada2/TADA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF63">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025024">
        <property type="entry name" value="Transcriptional_adaptor_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="11">
        <location>
            <begin position="27"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="12">
        <location>
            <begin position="105"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="109"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM97951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="590" mass="67442" checksum="FF6C9FB52E870525" modified="2016-11-30" version="1">MVSKITLEEEKAICRSSFKMLFHEELFTRSQCTCCQQEITGVGIECEECHNGNFRLCVECFSLGAEIGQHKADHKYRFFDSGSLVLGIKPNNANEVSTNQETEVEKTPRWSAREEIRLLDAIEQYGFGNWQDISKHIETKNPAEAKTEYVNRYVVGTLGELTWPGNIPNEVNRSVCNFQIQKPVDHTVPCDDGPLSPSLTQRLPPLEITPEEMLQLGYMPNRDDYEKEYDNEAEKLVSQLSFTAEDEEVEVGLKLALVDMYARRLRERARRKRMIRDYQLVSKFFKKEKTRSNGNSTDLLGTKESFKGQFAAYEKSLQEKLRPFAQFHNSREFEHLIRNLVKEKETKHRLTELYKYRSNGIRRLEECSEFERIKGLGAVKKQGLETITENQEGRSGIKKAATLAENSAAPLLVRQLQQALPSNSPKAKSSTLSNIVNEVSVGASASAVRNLTPQQFSKDDSNLRSFMELSESVRASLPLDLEDLKKAETLTQQLNENSSLLKEKLKASADQFTVDIIPSADLLTDKELQLCHRTNIYPAQFLTIKTALLLARKPKTDNQPNVELKEIPCPLNIHTKDWEHIVTFFKKNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYR1</accession>
    <name>A0A1D2MYR1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000383">
        <property type="protein sequence ID" value="ODM98081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYR1"/>
    <dbReference type="STRING" id="48709.A0A1D2MYR1"/>
    <dbReference type="OMA" id="IAICFTE"/>
    <dbReference type="OrthoDB" id="9909311at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="520"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="580"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="689"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="858" mass="97557" checksum="8F754FBF9510A78C" modified="2016-11-30" version="1">MMETEAVKGEVLTFESSDYEKELRLFKIREDLEPFFDVVSHQDLSVRCKLWKTGNCKYDGVNGVLKFNTDRGWYPFERHLVRVHKFSYENLIKGVSNEGLVAEGGTLPVPIAAPRRKRKRGREAFRTKCCVVCREFCLGSAQWEGSITELLENESTHLFPGSEGCTQLNQQLFYMYFLRKVVKFPTSKCEKYLKQCRGARMPETWFFLCSECKNLVSKAAELEEQIFVLQKKVTRIHDLVKKKTCGSVDRNTNAVLSDVATEVRKFILEPDISPPVARSSTKIVKPEVEETLLGEPSIENDDDWNASFQDDLNWESSVENSCTAVSQKSRRNRPSTSSRSHKRKKPLFVIEHEVVEDDCNEVLTNEEEVNESTRSLRIRRNIFLNENEVESGLQFDTIESCIKIDTDYPEPSAECLSEDDFTTETRALEIDNTEYPLPDSPTNDDDGDCDYVENEDDDHVSTSDDVSDESDSAPSSRKKSSKLTEGLIKKASESRPATVKRRLSNVGRLTTDDGDAETEYVCEICQSKYKNKKRFRDHQVAHEISKALGSRYECPQCSYPCTSEKARNIHISYRHGQNNFPCSLCSFVAPRKKQLTQHIRQHRNESQNDRVGEKFLCADFQYSETLKAHIKKVHPEAALGTQAGESGTKSESNASSSTAEYVCKHCGVQLSSQSCLSRHIKTHKELFGNKCELCGKSYATAQSLRRHKEINHTSNQVPCPYCDKTFPHKEYIRAHYKFCKLFPGRQELMGEPLEDSETSIPVGQPSQTLKLERETATNSSEQLKSERSQNVGHGTELVISPDTVDGSNIEFIQQTETTTEEMFAVQNAPGIIPPQFRLVVTTEGYQPITQHWTKEASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZK8</accession>
    <name>A0A1D2MZK8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">protein xylosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peptide O-xylosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_08201</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>UDP-alpha-D-xylose + L-seryl-[protein] = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12567"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132085"/>
            <dbReference type="EC" id="2.4.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; chondroitin sulfate biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Glycan metabolism; heparan sulfate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 14 family. XylT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.26" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000351">
        <property type="protein sequence ID" value="ODM98476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZK8"/>
    <dbReference type="STRING" id="48709.A0A1D2MZK8"/>
    <dbReference type="OMA" id="WENAHDI"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="UniPathway" id="UPA00755"/>
    <dbReference type="UniPathway" id="UPA00756"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030158">
        <property type="term" value="F:protein xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050650">
        <property type="term" value="P:chondroitin sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015012">
        <property type="term" value="P:heparan sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043538">
        <property type="entry name" value="XYLT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024448">
        <property type="entry name" value="XylT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025:SF3">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12529">
        <property type="entry name" value="Xylo_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="21">
        <location>
            <begin position="206"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODM98476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1021" mass="117242" checksum="B91D2DF7C7909656" modified="2016-11-30" version="1">MYILSKDGDEEIGVRYTKEMATRGQDISRFFLNYRKYVILIGIALVIQFFLAIRVVFLLPGSWDISGDGSKGPSYIRNHGSQKNVETLQNVKTNVDVSESISPQNTATPVKKTLPDSNASLLTFDVGSLTFVPECNITLKDSISAINRAKTQACKDEIANISCVITNDVLYVKRLPRYCSNKGESRDLYEYICQWLEKFELHQTVYGRYLGCFKDNPKDRILSGHLSLFKDRNSHQICIDLCLQSGFQYAGLQYGVECFCGNSKPSSYLKVENEKCGMKCPVEEVTSFIEPGHLTPWNGNCGGYFVMDVFETGVFQDYELNNKIVGLDGRREDGRLAEKPARTVRIVFFLTLNGRSARQVFRLIKALFHERHFFYIHIDSRQDYLYRELLSLTRILPKNVRFMKSRKATIWGGASLLTVLLSGMKDLVTNAEEWNWDWDYVINLSESDFPLKSTEKLETFLSHNKGRNFVKSHGRDVQKFIQKQGLDKTFYECEHRMWRVADRKLPSGILIDGGSDWIALHRDFVEYVIKSDDSLVSGLKTVFKHTLLPAESFFHTVLRNSNHCRTFVDNNLHVTNWKRKLGCKCQYRTVVDWCGCSPNDFRLTDWNRLQLAESRLLFFGRKFEAIVNQEIINKLEIWLYPDRFEPYYPTMDRFWLSIYHYHDIFPRPDDALVTLGRSLARVAARNFAAKYDCQVVRDQDNFVYQDGIAELVEMTAYNHDDKFQGILVRFKTSIARHVGAEGVPEVFTVHLEAWFGIKDQTEFAPWSQKIAKYRSKIQDISIGTDYDQKEQIFRNFAYSIGPFSEPILIYNIVADEPFNVTAVFIDPSNIVQAVQNSTTEVASGTTVSLTNFVKPVLRTPLQPGNWTVKVLSLDGYLLAEVKMLVLPIEFYQARKMTLANSKIINWFPSDEEYTDDDGSNIDSKYETLLQERIDRLVSEFYQVQDFCLESEQNHLLLSSFKTVSAKDVSQGQSKSLKMDQGSSSMDKMETSVCSHSQWSSMFPDPKSSITGIDPETGFLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N036</accession>
    <name>A0A1D2N036_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Membrane metallo-endopeptidase-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08025</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000337">
        <property type="protein sequence ID" value="ODM98653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N036"/>
    <dbReference type="STRING" id="48709.A0A1D2N036"/>
    <dbReference type="OMA" id="RDNQATI"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF241">
        <property type="entry name" value="GH26575P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="7"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="451"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="656" mass="75379" checksum="BE00228F8FEF1C41" modified="2016-11-30" version="1">MDVTADPCDNFFQFACGNWNKKHMIPEDRASISTFEVLSDQIQITLKGLLEEPVGNSDSEATKKAKDFYISCMNLSAIREQGAVPLQKLINNLGGWPVTQGFNWSPELSVEELIGRIRAELNMGVLLELWVGPDDKNSSVNIIQVDQMQLGLPSRDYFLNASREIHAYHMYMSELAVLFNATNITFAMEDLKKVIEFETSLANASLPEADRHDTSAIYKKQTLSSLERDIPEFNWKLYFKTFVKTELPSDEPIVSYAFPYLRDMALIVKTAEPRTVQNYVIWRVLMELTSHLIDKFQETKIEFRQVLMGVTSERERWHQCVEWTNKKVGMALGALFIRENFEPMAKETAQEMISNIRQAFIELLDENHWMDGPTRKVARHKALKMNERIGYPEFITRSDELNKEYLNLTISQTDFLENIVNFGKWKATQNLGKLRKPVNKDKWSMEPAVVNAFYDPNKNDIVFPAGILQPLFYSQYFPKSLNYGGIGVVIGHEITHGFDDKGRQFDSEGNLKEWWDNSTIASFRQQTQCIIDQYTSYTLNGLRINGKMTQGENIADNGGLKQAYRAFKKWERDHGTEPLLPGLEMMTHDQYFYLNFAQIWCGSMRPEDLLNKIRSAVHSPAPIRVLGPLSNSEEFAKAYSCPIGSTMNPREKCSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N050</accession>
    <name>A0A1D2N050_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Microsomal glutathione S-transferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000337">
        <property type="protein sequence ID" value="ODM98649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N050"/>
    <dbReference type="STRING" id="48709.A0A1D2N050"/>
    <dbReference type="OrthoDB" id="410651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="15068" checksum="ABF6DF2271306BE4" modified="2016-11-30" version="1">MPRVGEFLFGGSSLNIRDPQGLFFHIPSGYGYVVLTAVGSMVMVQWKAYQVGKARKEAHQNTLEQMPTFLSLLTFGGLEMPVFTAIGGAIWIAGRVAYAKGYYTGDPKKRMKGAFGYIGLLMILGATTKFAIHLIKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0H3</accession>
    <name>A0A1D2N0H3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="23">Glutamate receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_07871</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Postsynaptic cell membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000321">
        <property type="protein sequence ID" value="ODM98793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0H3"/>
    <dbReference type="STRING" id="48709.A0A1D2N0H3"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022824">
        <property type="term" value="F:transmitter-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06380">
        <property type="entry name" value="PBP1_iGluR_AMPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000186">
        <property type="entry name" value="Glutamate receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000087">
        <property type="entry name" value="glutamate receptor 4 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000001">
        <property type="entry name" value="Glutamate receptor ionotropic, kainate 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000143">
        <property type="entry name" value="Probable glutamate receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001508">
        <property type="entry name" value="Iono_Glu_rcpt_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00177">
        <property type="entry name" value="NMDARECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="9 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0628">Postsynaptic cell membrane</keyword>
    <keyword evidence="10 23" id="KW-0675">Receptor</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0770">Synapse</keyword>
    <keyword evidence="4 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="928"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1000"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1191"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="21">
        <location>
            <begin position="794"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="22">
        <location>
            <begin position="804"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="167"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="883"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="888"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1050"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1051"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1100"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="site" description="Crucial to convey clamshell closure to channel opening" evidence="17">
        <location>
            <position position="1029"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with the cone snail toxin Con-ikot-ikot" evidence="17">
        <location>
            <position position="1056"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="1113"/>
            <end position="1168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODM98793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1252" mass="139855" checksum="6F8BF45179F2216C" modified="2016-11-30" version="1">MPLCTVLGEDNAGIIIMGTTTAAQRGETFYNGLKQQRTLNESCQVEVEQQQQQGKWNKELNASSSSSLNHYVHHDDDDACRTTTATSFSHKKAAPLLNEASSCAKDNSRYRTELNHYYWDPPIGTHCFISAPQNCDCGRRETQCSGGGGCEGSRVISNGAIIYNNDDDDGNYLKEKRRRARQTPLEKSGMLTRSERKGRMEAKSSSSSTTTLSSSSSCALPFPSLCTPSTPPPGVRKDSQTSHKSVTFLLNLLLLFLLLHLSHDRLLSGAEAGNIPLGVVFEQGSPEIQSAFAYALTSFTPLNISSDPRDKFAFNAYVDTINTADAFKLSKLNHSDELLLCFSFRLFSESYCSLFLPGNLIIIIIPIMQSVCNQFFRGVYAIVGSMNSESFQTFHSYANTFQMPIVTPGFPTRPRKVSKFQVEQSLSLNSAMDFVTRGENSTLSPLVRSPLINDTFQKLLDTESTEQSQSREELLAKLVEEIVARESERLDFVTKIRPDLHQAIMDITAHYGWKNVIYLFHSNEGLLRLQSIFEKQGFKNESLRVRVMKRISSVMDALSIIRNLEVAQRFQPKHIILDCPASLAKDIIISHVRDLHLGRRTYHYLIAGLAFDEPWERSVVEFTAVNVTGFRMVDPDRKLVKDFLSKWATLDTNQFEGGGKRYISATAALMYDGMLVIKEAFTNILRENPEALRREKGRNLTCNSGVDFLNPIVPFEHGKLINERLRRVQAEGLTGHIQFSGQGSRSNFTVDVMEMTLESGQTKAGEWSDVNGFVTAQQLSDPLTKRKKPDQNREYIVTSILEEPYLMMKKAEKGENLTGNDQFEGFCKDLAEMIAKDMNIKYKIVLVRDKKYGAENPAAPGGWDGMIGELIRQDADMAISSLTITAHRETVVDFSMDFMEAGISIMIKKPQTEMPGAFSFVKPMRGTIWLASFAALLVVASVLLVVQGKVQASSNSNANANSADNSHTFPNTLWFSIASVFRQSTPFTPRSFAGRLVGSVWWFFTLILISSYTANFAAVRTVNRMVLPIKSAKDLSEQTEIQYGTLLGGSTFEFFRRSEVPVYKRMFEFMSGPNSLNVKSYDDGIKLVREKKGKYALLIESPKNDYTNQRKPCDTMKVGPNLDSKGFGIGTPLGSPLKHQINLEVLRLKENGVLSKLESKWWFERSECDVTNKQETATGDEELSLGSLAGIFYILIIGLVLSMVVSFLEFCYNSNKEAQKSKMTLTEAMKKKAKNTITGPIPAGSDPVTCIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N113</accession>
    <name>A0A1D2N113_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hemocyanin F chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_07694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000305">
        <property type="protein sequence ID" value="ODM98986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N113"/>
    <dbReference type="STRING" id="48709.A0A1D2N113"/>
    <dbReference type="OMA" id="WISSTTH"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006582">
        <property type="term" value="P:melanin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1520">
        <property type="entry name" value="Hemocyanin, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.10">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005203">
        <property type="entry name" value="Hemocyanin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037020">
        <property type="entry name" value="Hemocyanin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF4">
        <property type="entry name" value="PHENOLOXIDASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03723">
        <property type="entry name" value="Hemocyanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904870" evidence="5">
        <location>
            <begin position="31"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="domain" description="Hemocyanin middle" evidence="6">
        <location>
            <begin position="196"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Hemocyanin middle" evidence="6">
        <location>
            <begin position="301"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Hemocyanin C-terminal" evidence="7">
        <location>
            <begin position="460"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="741" mass="84170" checksum="90A30CE4127D358F" modified="2016-11-30" version="1">MIGSLVLPGKMEVFRAVFVLFAFLLKNCNSYNSHISHNSHISHTTPDLDHYSVEPTRETYSKDYYYDYQDYQSEGTTGSYPNNGGSMQDNFSALFDWRTHIPTSGNDTFLDDDRRFLRDIAETCPKRGFFYGMNPSHNSAVLRLNQILMEQSSPEGCLQMAGSLRDRDEVNPHAWLRAVISASIFRSDLQGLRKPPLVEVMPSMFVPGEILNDLKESASNEVSTNSQKCVRVDGSFGEDNGDENLVWYWREDVLLSSHHLYWHLSYPIRGERGAQDREVISWFATCGTLGFETWADHSIWYNPHLHDGNSGANYSARPPGVPVSDLVSDRPVSVRNRTIWLNRVLDGIAEGRLIDQYGHPVYLDNDDGINILGNTLQSNALSVNPDYYGENGVHNSGHRIIGAALDPRLELGHPPGVMGEDATAIRDIIFYPYHAWMDTIFNAQKNRLAPYELHKGAWPLVLPGIELQSIKIHSGDLPRNKLHTFWSYKRYDLARGLDFNRSANARGPLYACHQHLEHQDFEYELEIERKDESFDAKTATVRIFMGPRYDLEGRRYTLDEQRHYMFIVDAFTVPLKVGPNTIRRPSVSSALTVDFPTSLGELRQEPTNANIMPYCGCGWPQHMLIPKGTKKGLDLDVFAVITNSKEDAVKRDTSTRTQKCRAAWIFCGIADEKYPDARPMGYPFDRRLYITEQKRPGPGALLEHLVKDVPNMASVPIKVMHFDEIRGGDAVGDLIEDYHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3W5</accession>
    <name>A0A1D2N3W5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Structural maintenance of chromosomes protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000243">
        <property type="protein sequence ID" value="ODM99958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3W5"/>
    <dbReference type="STRING" id="48709.A0A1D2N3W5"/>
    <dbReference type="OMA" id="TECSNGM"/>
    <dbReference type="OrthoDB" id="7417113at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="899"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="269"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="508"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="690"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1123" mass="127179" checksum="0BF4D53B39650A00" modified="2016-11-30" version="1" fragment="single">LEEKLGQLQKKKLILQNRLAAEKKCIEQLRVKILQMQEREEDLCSQISRLESLLQNYEQRNFELEESCIEMKCSVQFVIHSIPIFALCYFGALLRSAHGRSSSVLNILLSLPATVGVNIGRYLHVTNNSNALPFVPDVFVSPVPPTRKHKLRELSSPTVSEEVEPKLKKLRRMLDKNGITCLCSCANCGNGRLSITDDDGSREQALMTQNHAEVQTGEELWKLLVEQIFAEQKGEWQKTEKVLLKKIEVLECDIDKCQEIFDRERGSLIKIYEHKLAEKESQLRETQACRNEKRDLQEKWNCLIQELEQFALYLGKNLSERSEEQQQEQQYDEDEGNTLSSSAATTMVVSGKDDTLFVRAPTQLEVTANPATGTISPFAEVEDVDIESNEQRMPRFISSSIIKSLRDTSANDAALTVSGNDEGHGQDTEVLQKTRIIYYLQSSLKEHLSTFEKREKHLLDQIDQLTQEIRQHSQQDSQHEGDMIAYLSQENERLVSLFQDHEKVWGDLQQLQEEHEKLKLEVGNIVTIRKKLEDSQKVEAEMRDRLEELERTESHLKSQISQLEKKEAKALEKIQQLRDEIQFLRTKCCQLQDDIDSRVTREAKYKNELQALTVKLKESSLELEEKESQLESNETALQAQIQKLKNQLTELHQAYADTECSNGMLREEVSYLERTVEEAIAKAVQSENTVTALSHELKQKDLTIEELQRKLQQLTTHDPIASNVLSTSSSALNPNDLADFNKHDGGLLGVARDVEEVVTLLQGQCIDGDTVIYLNDVVVESDNTKLSNKEEGGEEEDLMIANLQEMMTNLGSQIRNLEDAFYIRQKELRDSYMTETSWWKMRCEEKNKLIELLGRRIAQLCVTDIHGYFLDGILREIEKVRASIGTCHLLTAHKESRELSRNRDSSSCSPLSTSSASSSTTMITCSPSPPARQSWCPVEPPPRKRTSKKSKASSISVTTANPNHPTKPILPSDFTCDSLCSYLVAERKRVMAILEDALGENTVIDDKEGSGANTSGESSSTALTFSSVGTAMESSTTGLEFRVLRKIGEDSLLVSWSMPENHLLPTNVSGYEIAVNGKVFLRIPQPNRHKVILFGLNLDEPLHLTLRCSGDEGLEESTITYIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4H7</accession>
    <name>A0A1D2N4H7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">lysozyme</fullName>
            <ecNumber evidence="2">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_06504</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000228">
        <property type="protein sequence ID" value="ODN00174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4H7"/>
    <dbReference type="STRING" id="48709.A0A1D2N4H7"/>
    <dbReference type="OMA" id="INCANDP"/>
    <dbReference type="OrthoDB" id="6337871at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031640">
        <property type="term" value="P:killing of cells of another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16890">
        <property type="entry name" value="lyz_i"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.530.10:FF:000019">
        <property type="entry name" value="lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008597">
        <property type="entry name" value="Invert_lysozyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11195">
        <property type="entry name" value="DESTABILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11195:SF13">
        <property type="entry name" value="INVERTEBRATE-TYPE LYSOZYME 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05497">
        <property type="entry name" value="Destabilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51909">
        <property type="entry name" value="LYSOZYME_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="4" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="59"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="64"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="115"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608597-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN00174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="186" mass="20526" checksum="70286041FAB21B53" modified="2016-11-30" version="1">MAKINAFSLIAIYGLMAFTVIFVSATPQRRFSGVDDLTGQSSQNTGSRRKAINPMTEACLACICQASTNCNLTTRCISNGKYCGPFLISRPYWLDAGQLTLIGDRAERAGAFEDCANDPICSAQTVRTYMQRFQTDCNRDGAIDCDDMGRIHLMGPTDCVNPRVPTTPFFKRFRSCYDKVLQLSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N528</accession>
    <name>A0A1D2N528_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein UBASH3A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_06303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000211">
        <property type="protein sequence ID" value="ODN00379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N528"/>
    <dbReference type="STRING" id="48709.A0A1D2N528"/>
    <dbReference type="OMA" id="KWAITET"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="274" mass="31417" checksum="327BC6C0AB404C64" modified="2016-11-30" version="1">MSRNRRVVIVRHGERVDHRFQDAWIENCFDNEGTYSRQNLNQPEQLPKRQGYPQTFLRDTPLTEIGSLQATLRGQGVGAASILANNVEVFTSPSLRCIQTATNVLKEWSFFVGMKRSDLSLNIEPCLFEWTQIKWYLNGNMPKWMTSEELIEAGFNVGRNYIPFISNEDLKEGEEINNYYERSHKVICHLLNYTDADILLVAHGFTLEVVSRGLLGKPSRTAEETLDVCSNIPYCGMIILEQDSITKTWGILPLPQQLQLKHESAHEFDACKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N693</accession>
    <name>A0A1D2N693_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Cytochrome c oxidase subunit 5A, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Cytochrome c oxidase polypeptide Va</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_06073</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Mitochondrion inner membrane</location>
            <topology evidence="1 15">Peripheral membrane protein</topology>
            <orientation evidence="1 15">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the cytochrome c oxidase subunit 5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000197">
        <property type="protein sequence ID" value="ODN00595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N693"/>
    <dbReference type="STRING" id="48709.A0A1D2N693"/>
    <dbReference type="OMA" id="MEKWPAD"/>
    <dbReference type="OrthoDB" id="5778907at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00923">
        <property type="entry name" value="Cyt_c_Oxidase_Va"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.40:FF:000002">
        <property type="entry name" value="cytochrome c oxidase subunit 5A, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.40">
        <property type="entry name" value="Cytochrome c oxidase, subunit Va/VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003204">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036545">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02284">
        <property type="entry name" value="COX5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48479">
        <property type="entry name" value="Cytochrome c oxidase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 15" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN00595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17874" checksum="9065EBA7AA00CA71" modified="2016-11-30" version="1">MMRLFSQRMQTAVRGSLTAVNRNMQPAAATGAARFMSHEVQETDEEFDARYVAYFSRPDIDGWEVRKGMNNLIGMDLVPDPKIIIAALRACRRLNDYSLTTRFLEAVKMRAETNKDIYPYVLQEIKPVLEELGISTPEELGYDKPELALKSVFDVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N745</accession>
    <name>A0A1D2N745_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane-bound O-acyltransferase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05598</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000172">
        <property type="protein sequence ID" value="ODN01090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N745"/>
    <dbReference type="STRING" id="48709.A0A1D2N745"/>
    <dbReference type="OMA" id="FTGPMMI"/>
    <dbReference type="OrthoDB" id="286734at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="428"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="539" mass="61814" checksum="FE605ADCFFD8D136" modified="2016-11-30" version="1" fragment="single">PNFQVNFITCQVVALCFSLSMKRWIKDPHTKLIYTLICGLGICLFCFGNQIFHIIASAGLGYILIKANKSSNMPWIVLGANMFYLSSLHLQRQFFDELGSYSLDITGPLMVLTQKVTSLAFSLQDAIDQKKSDDYKGTEMQKKYAVLEAPSFLEYWSFVFQFQSMLAGPLVLFKDFREFIHTDEFPSPLHAVVKKMGVSVFFAVVFIKVTPVYSIERLKETEFLWDTTFLYRMFYVTIATMMERAKYYHAWILADAVCNASGLGYDKQSQTWDLVTNVDALGFELGLNLKESLDSWNRGTMKWLRHVVYERVNPSIRTVATYAMSAIWHGYYPGYYITFLSGSVFTSVARQVRKIVRPLFVNDRSLKLVYDFFTWLTTRFVIAYVTFSFIILDFTPSILLYLRLYCCFHFAAFGAMFALPKLSKHLKNRGTRTQPQPATRVVTDAQPQKDKTEPKKDTAQTPATEVTKPIKKESETTTPKRGDDESYYGPKTATKELISHEYPEIKSYLRNSKPTNDVWTTWTMNSAAMNGNAVQLKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N775</accession>
    <name>A0A1D2N775_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isoflavone reductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000181">
        <property type="protein sequence ID" value="ODN00925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N775"/>
    <dbReference type="STRING" id="48709.A0A1D2N775"/>
    <dbReference type="OMA" id="QPEWEGK"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="18"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="35358" checksum="0F6F6A92E9DDB4EB" modified="2016-11-30" version="1">MGNCFCKQKRKMTDPPVVAVIGSTGYVGKCVMPSFLNSLKDGKLKELRVLTAPEKLNSEIIQSYVSAGAKAISVDYKQVSSVTTALNGVDVVVSTLGLGEGVEDVRTQLLDALVAAKVKLYFPSEYGANHYKFLNYNHPLFEGKRKHFKQAKERGLNTIRMLTGGIMESIFGKLDCVSGVLTLAGNAADIPCAITAERDLGPFILEAIFLAYSDIAKCPDEIEVYSDMKTMREYANGFDKVSGLVTQIEQVPLEEFKAEYEKSAKPFVKLLMIMFAEGAFDFSNATGNQLLNPNETVWKLKRIEEYAKETGGMPWKDGKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N776</accession>
    <name>A0A1D2N776_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron-sulfur cluster co-chaperone protein HscB, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000172">
        <property type="protein sequence ID" value="ODN01082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N776"/>
    <dbReference type="STRING" id="48709.A0A1D2N776"/>
    <dbReference type="OMA" id="NDICESR"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Co-chaperone HscB C-terminal oligomerisation" evidence="3">
        <location>
            <begin position="213"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="294" mass="33225" checksum="8B283E3DBECB759E" modified="2016-11-30" version="1">MTSRAIISSVIYKVPRVGGLSSRTLSSSGRSTCLPAQNRTSVTAFSFADRQLSLVRTSGSVLRVSSNSSSATFRNYSSIVSVNCSKCAHSYSNDQNISDFVSQVTCPKCGALQKRNLPELPDYFSILGHTKSYRVDLQNVANKTKQLQKRFHPDLYSQKGSEQQNLSQEYSSLVNKALYTLLDPIARGRYMLTLAGLSPEDPDGDLERTMTSDPEFLEEVMELNERLEEINSEGDWKDFRNQNEETLKEIHEELEKAFEKGEIKEAQRLLGRMKYFDTLQHKLKDLQSRIGVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7B3</accession>
    <name>A0A1D2N7B3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Complex III assembly factor LYRM7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">LYR motif-containing protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05727</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UQCRFS1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000179">
        <property type="protein sequence ID" value="ODN00965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7B3"/>
    <dbReference type="STRING" id="48709.A0A1D2N7B3"/>
    <dbReference type="OMA" id="TRQYVFH"/>
    <dbReference type="OrthoDB" id="529194at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050435">
        <property type="entry name" value="MZM1/LYRM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749:SF1">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="9">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN00965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="111" mass="12696" checksum="0ABEF0892BAB2EB1" modified="2016-11-30" version="1">MSALSTGRVQALSVFKQLLRTRQQVFRGDQNALQAARDKIKTEFLKHKAETDPGKIDELIKVAKESEELLRTKVIQAQEVKPHVFRIRKDHFTERCVTAKRERCADCTCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7D3</accession>
    <name>A0A1D2N7D3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Filamin-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05523</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the filamin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000168">
        <property type="protein sequence ID" value="ODN01178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7D3"/>
    <dbReference type="STRING" id="48709.A0A1D2N7D3"/>
    <dbReference type="OMA" id="DIEVTWR"/>
    <dbReference type="OrthoDB" id="264520at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044801">
        <property type="entry name" value="Filamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001298">
        <property type="entry name" value="Filamin/ABP280_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38537:SF8">
        <property type="entry name" value="FILAMIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38537">
        <property type="entry name" value="JITTERBUG, ISOFORM N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00630">
        <property type="entry name" value="Filamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00557">
        <property type="entry name" value="IG_FLMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="Filamin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="130" mass="14109" checksum="C81C99878598FA30" modified="2016-11-30" version="1">MATVEAHGGGLTFGITGSKCRFTVYLEDFKEGAKIVDGLTVAIDGPSEPEIEFDHQDNGDIAVAWTPYAPGNYVLTLKFNGDQIKDSPFNIKVVGDVNTHGQYQAPKKQIYTGWAARRKSSQASQGKISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7J0</accession>
    <name>A0A1D2N7J0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NFU1 iron-sulfur cluster scaffold homolog, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05761</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000181">
        <property type="protein sequence ID" value="ODN00926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7J0"/>
    <dbReference type="STRING" id="48709.A0A1D2N7J0"/>
    <dbReference type="OMA" id="IFEHIME"/>
    <dbReference type="OrthoDB" id="21550at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000001">
        <property type="entry name" value="NFU1 iron-sulfur cluster scaffold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.70:FF:000002">
        <property type="entry name" value="NFU1 iron-sulfur cluster scaffold homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.70">
        <property type="entry name" value="Scaffold protein Nfu/NifU, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014824">
        <property type="entry name" value="Nfu/NifU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036498">
        <property type="entry name" value="Nfu/NifU_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF1">
        <property type="entry name" value="NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08712">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00932">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110836">
        <property type="entry name" value="Hypothetical protein SAV1430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Scaffold protein Nfu/NifU N-terminal" evidence="10">
        <location>
            <begin position="87"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN00926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="35726" checksum="66C9A2FE22B5889D" modified="2016-11-30" version="1">MLSRSFRLLNISREARALPICSFANGSSTKSTLSTKSEGSFGERSYASSAWTFQCLSDKTIGNVNLGKGRLMLSLINSHVPSRSMFIRTQETPNPNSLKFYPGTQVLESGTMDFPTPASATNSTLAKMLFRIEGVKSVFFGLDYITVTRMDEEVEWKLIKPEIYATIMDFFASGLPVFTEVKVDSAQGSQKSDSQSEDEEDETILLIKELLDSRIRPTVQEDGGDIQFVEFKDGIVKLLMQGSCTSCPSSVVTLKNGVQNMLQFYIPEVLGVEQVIPEHEKIADAEFAKLESKLEQKVKEKLNDGSEYDPILKNIKPKPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9L1</accession>
    <name>A0A1D2N9L1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Apyrase</fullName>
            <ecNumber evidence="2">3.6.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_04749</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:36795"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="3.6.1.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:36796"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the apyrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.5" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000133">
        <property type="protein sequence ID" value="ODN01942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9L1"/>
    <dbReference type="STRING" id="48709.A0A1D2N9L1"/>
    <dbReference type="OMA" id="RDEHMGC"/>
    <dbReference type="OrthoDB" id="25028at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004050">
        <property type="term" value="F:apyrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045134">
        <property type="term" value="F:UDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030166">
        <property type="term" value="P:proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.100:FF:000001">
        <property type="entry name" value="Soluble calcium-activated nucleotidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.100">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009283">
        <property type="entry name" value="Apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036258">
        <property type="entry name" value="Apyrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13023">
        <property type="entry name" value="APYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13023:SF3">
        <property type="entry name" value="SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06079">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101887">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1199">Hemostasis impairing toxin</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1201">Platelet aggregation inhibiting toxin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0800">Toxin</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR609283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN01942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="418" mass="46859" checksum="B1EDA874E97EC3B0" modified="2016-11-30" version="1">MSLAEWRQAIVAPTTYRVGNSTVRLQTRFIAIIVVFSVVALLYIAYPFQGSGAENHFRSQPSALSPSLNEIPDGAGAGGKKAAVLWSTHRRIVLDTPYPLTKPVSTEKGLRYRIGIITDLDLESKTSTGKWISYMRRANLFLQYKKDDPKSSKVTIEWENGEPHIIKSGVNEDGRGMELSELMIFNGKLYSCDDRTGIVYELTKLDAEEVVPVPWVILADGNGTVSKGFKCEWSCVKGDHLWIGGLGKEWTTSSGELVNHNPQFVKSISAAGEIRHHDWKLRYQKLAKALDIVFPGYVIHESGGWSDVWKKWVFLPRRASKEQYNDKTDEKKGTNIMLLTDEDFTNVEVRHIGDVIPTHGFSSFKWIPGTGDNLIVALKSEEIDGKTASYIMVFDMDGNILVPETKVGDHKYEGVEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9P0</accession>
    <name>A0A1D2N9P0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Osteoclast-stimulating factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_04870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9P0"/>
    <dbReference type="STRING" id="48709.A0A1D2N9P0"/>
    <dbReference type="OMA" id="ISFWNTE"/>
    <dbReference type="OrthoDB" id="207120at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11772">
        <property type="entry name" value="SH3_OSTF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24155">
        <property type="entry name" value="OSTEOCLAST-STIMULATING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24155:SF10">
        <property type="entry name" value="OSTEOCLAST-STIMULATING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="20472" checksum="E0C0EB4F1A5BC240" modified="2016-11-30" version="1">MAKPVPPKIAPKPGKVTVLRALYGYTAQQEDELTFTEGDILYLVDQTDANWWRARCGMKVGLIPSNYVEMKMDAIENPLHDAARRGNIDFLKECLTNGVSATGLDASGNSPLHWSAKGGHLECVQEIIRAAMKTYRNPKHFINAQNKLGDTPLTAQPAKTTCQSSISFWNTEQIPQSKIKTNSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB23</accession>
    <name>A0A1D2NB23_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000121">
        <property type="protein sequence ID" value="ODN02196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB23"/>
    <dbReference type="STRING" id="48709.A0A1D2NB23"/>
    <dbReference type="OMA" id="THWTETE"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF176">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="181"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="398" mass="44402" checksum="8F17D7EF4EF0915F" modified="2016-11-30" version="1">MPLDQFAILLDNPSMSYFPGQMVSGRVVIRANSEKNTQGLKLKFEGKASVHWSEEKTERTGSGNDATDRKVTKNFDDSDNFFDFKNYLLGDGRSDVKIPPGESSYPFSFQLPLMNLPSSYVGQHGKVEYLLEANVKRSWKFDYNAKQFITVNSIVDLNNDPQAAESGDWKTSKTFCCLCCASGPLDMHVRLKNKGFVPGEIIGLEVEINNLSTRGINDISTQLVQEATFFAQSSKNQSFKPIIDMKRSQGVDPGDSDIWRAELLVPPVPPTKLGGCRIIDVQYVLKVEAHVSGVAFNLKHSCPIVIGTVPLRARFEELKGTETVIPTAPPMFTPSGYPDLPQPRYQDSYNFKLDPPKPDNIVDTVTNTVIDNIVPSEPDYVPQYVTYGWKFNIPAELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBF3</accession>
    <name>A0A1D2NBF3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000105">
        <property type="protein sequence ID" value="ODN02579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBF3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="362" mass="41308" checksum="A8436CF4825E8BB5" modified="2016-11-30" version="1" fragment="single">YKDDCQLSGCTRTDEAAGVGSPSSTGRSDDDDTHTDAEDSTPTKKGGKAEGDVEDVNDNVNRQLLIYAVEMAFPHFTGPTDSMMTAPRNSWILLERIFELAKQTCYKIVKPDFLSRVLKYFKIAHFGENFEYDEYFSDTDTQQILSMLDVCQERATRYREMDIEVDTCTGQASMVRIEDKTKQIISRSSDDTGYQEVRHHHVMEVTWDVIDMWNAVCISEFKSSYLLYHRLETGLELLFNDKLRKLWHFPNVTEEYYQKLLGPDEGIQLLNLHQCVMAAYKGNARINRMERPNKGRNTVMGSMIRSRLNDETLKKGISGRSMGNPNSEIKAACIKGPTIRCHRKPSKNKRGNGLLSLINKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBX3</accession>
    <name>A0A1D2NBX3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase 47</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin thioesterase 47</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-specific-processing protease 47</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_04184</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000109">
        <property type="protein sequence ID" value="ODN02496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NBX3"/>
    <dbReference type="OMA" id="RICTIKP"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045578">
        <property type="entry name" value="USP47_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF702">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19718">
        <property type="entry name" value="USP47_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="12">
        <location>
            <begin position="192"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="444"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="852"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="883"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="932"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1283"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="942"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1283"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1312" mass="148432" checksum="5369B8E07D3B67C9" modified="2016-11-30" version="1" fragment="single">DDVTTKEELPIVEIDDKAALKTITTVLETESADTPQDDDISTPQNLDAELPPRSPSKPDNYITVKIKDFSGVLEKTEAQLFVFSTDTTFADIFVDVSCRFDIELGEFDIIFQDKSFSYNLGGLPDDQTLTSLNIVPDCDRTYWMSLDIFPQKKRKSRDTIRALGLESVSENENTSSHATDSCSSFGGKRDFVGLKNRNMTCYLNSFLQGLWFTPEFRNALYNYVYEPGRSNRKSLCHPLQKLFLQQQFSIRDSIETDELIRTFGWEDRETWNQHDIEELCSIFMENLTAEFKGTSLDGIIQALYFGSLDDYVKCLECNRVSQRTDDFLVVPLPIRNFGSLLPNPTLEAALNSFVAYEILDGNNMYNCSQCEKPCPAHKGLKFNRLPYILTIQLKRFEYDFIKDRRLKLNDRVAFPYVLDMNSYIETPSPDRRESLKIDMLKPGSMSVEGGRSSHSRPSVSLVDPEENDEPSQTTEEGAVGGEKPSLEQMIELRNTKGPEIYQLYGVMVHRGGINSGHYYAYIMDFERGKWFRCDDAAVRKVTKSDIEGAYGGDSDDDKELTSAYMLLYRRFDPDLNLLPYYLNDMPAHLQDMWNSTVILDKACHEEEELAKNTVRMPVLFRDPETNPTLQEKMVAIPKTLTMDEAANFVFKEIFPKVEQPPEEGTIRLCRYDKDLDVIENSFDNCEHMFIVTAIRHRPPVTKNEALLLERKEPKLEFDIFRHDDYIFRTSMIDCLEEDLLQVDEIHASPSETVEELMKKVQLRFSITEPITLVANFMSRYCSISGEKTPLSLFKFDRVNNLYFQAGTEEGLSDVMLDFVEHYTKAEIIEIHVQTPPHAVGNTSSGEKAITSEAEANTEVPKQAQPEATKVSNVSEAADLVNAATKPGAPKDTAPSATATLKTAATPETVKTVNETKPSENAVWYGSKITSIRSVNGGPPPSSNDASGSVPQVTATNSEPASKATGIKALAQKNGHYMKFMNKSETPEVGVYVYTLRIDGQTPLYALSKRVSQLISTNESDFVIYKIDGNETTELRRMTERICTIKPIDRFLVKLEHRLQDGESRIAISLLNVGCLDKPSEYLTDIVVTLKMNVDEVKSAILKKCETLQNDTNVDITKMRIRKKLRSSPSKIMRANAKLQDIFTVTSIQSGELFLQLLDSPCELTDKNYCFIYRHWHPSTGVLDATVEVTVFHDHSESLEDVILSKIRESLGVANDIELEAAKPDGHYPWSISPRVIQDLGWFSLSPPVKKSLYVYNDELVLFVRDKNEAPKEFYEYQAEPSIPTTGRRTVSSVAEAPRREPGLKLNLAQSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC45</accession>
    <name>A0A1D2NC45_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">1-acylglycerol-3-phosphate O-acyltransferase ABHD5</fullName>
            <ecNumber evidence="5">2.3.1.51</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Abhydrolase domain-containing protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">Ocin01_03826</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="27">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors. Functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Regulates lipid droplet fusion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:37455"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:74938"/>
            <dbReference type="ChEBI" id="CHEBI:74941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:37456"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:37443"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57368"/>
            <dbReference type="ChEBI" id="CHEBI:74544"/>
            <dbReference type="ChEBI" id="CHEBI:74928"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:37444"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:37131"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:74544"/>
            <dbReference type="ChEBI" id="CHEBI:74546"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:37132"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:37143"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74544"/>
            <dbReference type="ChEBI" id="CHEBI:74551"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:37144"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:37147"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="ChEBI" id="CHEBI:74544"/>
            <dbReference type="ChEBI" id="CHEBI:74552"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:37148"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:33187"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57518"/>
            <dbReference type="ChEBI" id="CHEBI:64839"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:33188"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>1-octadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:37163"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:74560"/>
            <dbReference type="ChEBI" id="CHEBI:74565"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:37164"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:19710"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:37451"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57380"/>
            <dbReference type="ChEBI" id="CHEBI:74544"/>
            <dbReference type="ChEBI" id="CHEBI:74937"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:37452"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC45"/>
    <dbReference type="STRING" id="48709.A0A1D2NC45"/>
    <dbReference type="OMA" id="AFHSMMQ"/>
    <dbReference type="OrthoDB" id="7457040at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000019">
        <property type="entry name" value="1-acylglycerol-3-phosphate O-acyltransferase ABHD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0221">Differentiation</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="27" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="26">
        <location>
            <begin position="112"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="390"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="25">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="25">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00036296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00040731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="ODN02833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="430" mass="48315" checksum="A4E38AC4EBEFF005" modified="2016-11-30" version="1">MMQGREFKGQLPGDFQENTNSAVVTKLMDSRNQTTGIIDTGEDFEEKEGWIRSWLKWCPTSMSLLRAAEKRILSYVKTPYKGQYVNIGPTVGKDESKIWTISLTENSPEKLPLVLVHGLGSGVALWALNLDGLASARPVYAFDLLGFGRSSRPNFSNDALDAERELVQSMEEWRREMKLERFVLLGHSMGGFLASSYAIRYPSRVSHLILADPWGFPEKPSDLSQKYPIPLWVKMIAYFLQPLNPLWGIRVAGPMGPKLIEKVRPDLIKKFSILSEDGDAKIADYIFHCNAQTPSGESAFHSLMSSFGWAKYPMINRIPSLRKDVPMTLIYGSRSWVDHCPGAIIQQMRPTSYVDVQIIQGAGHHVYADKRERFNELVLKAAAFSDENEISRYSGSPEKTPESTKSVDEKEIHVAVKGSSDSQHNISKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC70</accession>
    <name>A0A1D2NC70_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Armadillo repeat-containing protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03834</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC70"/>
    <dbReference type="STRING" id="48709.A0A1D2NC70"/>
    <dbReference type="OMA" id="KGTDQHV"/>
    <dbReference type="OrthoDB" id="5559898at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000061">
        <property type="entry name" value="armadillo repeat-containing protein 8 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000070">
        <property type="entry name" value="armadillo repeat-containing protein 8 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038739">
        <property type="entry name" value="ARMC8/Vid28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651:SF7">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="667" mass="73778" checksum="4B1A4857FCE998FE" modified="2016-11-30" version="1">MSVDVMSNVVDNTISSMEVEEPPQHVQDLYSDDPDKLLEAVSRLKNMVIGSNRQKSIAIKHGILPRVLALLGDVQWGDEIRRESCIVLGSLVKGTEENVRAVVDALSVPVLIRVLSSEDAILVEYSLTCLKTVFSHRFAPKDMLYSDPGLIRHLLSLMNESVANKISVASILSDACSSADHQITLANHGVVTHLAALLVSPSIKVQMPAVKCLTEMSYKNEHVSSVIAETVYNGKKLPDLLITLLSRDKPDKMQLQVAACFTYLHRANALPPTDDKVCMKTLPCLVRMCSKEHDTETRVVAAETLSYLIEVDKELQATAAISNRLISTLSEFLKPQQIVFKPLTGTTAVMHKAAFKAFASLGANDEQIRKRIIETEPLMEKVVECLDEPNPDIALAAVRCLHSLSRSVQQLRTTFKDHSVWKPLLKLLQHTRQDILAVASSTLCNLLLEFSPSKEPVLESGAVEVLCNLTRHEDVGLRLNGIWALMNVAFQADQRLKSQILVTLGMDQIFRLLSDDEANIVMKTLGLLRNLLTSAAHIDHIMGLYGKQIMQASILILEGDHGPETKEQALCMLSNIADGFSAKEFIMTNDDVLKKITSYLSHSSPKLQTAAVMCVSNLAWKEEDGSLERQAKLKELGVQKLLHSLITTSDQNLFDRVKTALNQFSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCA5</accession>
    <name>A0A1D2NCA5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCA5"/>
    <dbReference type="OMA" id="HASINDC"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905343" evidence="2">
        <location>
            <begin position="18"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="354" mass="32581" checksum="ED23CA5CB7E4303B" modified="2016-11-30" version="1">MAKFIALLIATMAVAYAQEGGRGGRGGGRGFGIGGGIGAGIGIGGIGIGAGIRGGIGIGGGRGGWKSGGGRGEGGRGGGEGGGRGEGGRGGGEGGRGGEGGRGGGEGGRGGEGGQGGGEGGRGGEGGLGGLGGLGGAMLGGLEGMGGLNGLNGLGGLGGEGGRGGEGRGEGGQGGEGRGEGGRGGEGRGEGGQGGEGRGEGGRGGGEGGRGGEGGLGSLGGLDGGLGGLNLGGLGGFDGGFNGLGGGLSFGGLNFGGLDGGLGGLEGFGGLGDEAEEEKVDLEVVEVVKEAEEEKVDLEEDGDGEPPLTFNAMTATDGEDLMEVWEEGSAVAEEVKVVEGVRVAEKAPVVNLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCM7</accession>
    <name>A0A1D2NCM7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proliferation-associated protein 2G4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCM7"/>
    <dbReference type="STRING" id="48709.A0A1D2NCM7"/>
    <dbReference type="OMA" id="SRMFYSE"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000013">
        <property type="entry name" value="DNA-binding protein, 42 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000029">
        <property type="entry name" value="Proliferation-associated 2G4, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004545">
        <property type="entry name" value="PA2G4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00495">
        <property type="entry name" value="crvDNA_42K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="3">
        <location>
            <begin position="19"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="357"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="389" mass="43179" checksum="CD5B3CFF6C1DEB9F" modified="2016-11-30" version="1">MADKDDLEKTIAEDLVVTKYKMAAEITNKALKAVVEKCVVGTSVREICILGDKILVEETGKQFKKEKELKKGIAFPTCISVNNCICHFSPLNSEPDYVLKEEDVCKIDMGCHIDGFIAVVAHTAVVAPASGKITGRRADVCLAAHYASEAALRLVKPGNESDKVTDSVQKIAESYKCKPIEGMLSHQLEQNRIDGEKTIIQNPNEAQRKEYEKCVFELHEVYAVDVLISTGEGQGRELETRVSVYKRTEDQYMLKLKASRAFFSEVQNKHGNMAFNLRDFEDEKKAKMGVVECVKNKLIEPYQVLYEKPGEVVAQFKFTVLLMPAGSHKITGLPFDPTLYESEHKIEDEDLKKLLASGVNPNKKKKKNKAAAGSGDAKAKAGQNGENEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDE6</accession>
    <name>A0A1D2NDE6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03396</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDE6"/>
    <dbReference type="STRING" id="48709.A0A1D2NDE6"/>
    <dbReference type="OMA" id="KIFQWAA"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090433">
        <property type="term" value="F:palmitoyl-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="9">
        <location>
            <begin position="116"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="706" mass="78975" checksum="4355DD6F1E5B6194" modified="2016-11-30" version="1">MAFAEVLIKGILWVVTFLWDFLTLPFFYIYQQPWKKTRDFKEPKAQAVSHEGGITYRSITPISAMHIELEQKKIDTMDKVFQYAVKRNGSKRCLGSREVIDEEDEMQSNGKVFKKYVLGDYLWKTYNEVDRLSVCFSKGLRELGLEPKGKIAVLAETRAEWLISAMAAFRQCITMVTLYATLGEDAIVHGLNETEVDYVLTSHDQLPKFKNVLKHCPKVKTIIYMEDPLNKTDTSGYREDVEILAFCDVIARGSRSGKGTHEPAADDIAIIMYTSGSTGAPKGVLLSHRNISIAMMAFSDALGPVYPDDIYLGYLPLAHVLELMCEAICFLSGIPIGYSSALTMIDSSSKIKRGCKGDASVLRPTIMASVPLVLDRIYKGIQEKMNAGGGVAKAVFEFFYQYKMKWYYRGYQTPLTNRLIFKPVRRVVGGKVRLLASGGAPLAPDVHEFVRTSLCLPLLQGYGLTETAACATISLCSDMSTGRVGAPLGCCDIRLVNWDEGNYTVNDKPYPRGEILIGGDNVALGYYKMSESSNQDFFEEDGRRWFRSGDIGEMQKDGVLKIIDRKKDLVKLQFGEYVSLGKVEAELKTCPIVENICIYGDPSKTFCVALIVPNPKYIQTVADKLGRSGLSFEMLCNDPEIEQAVLKEIQSHGAKCRLQKFEIPGAVKLCIEVWSPDMGLVTAAFKLKRKNIQDRYQGDINRMYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEH4</accession>
    <name>A0A1D2NEH4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen debranching enzyme</fullName>
            <ecNumber evidence="5">2.4.1.25</ecNumber>
            <ecNumber evidence="6">3.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Glycogen debrancher</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_03049</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of (1-&gt;6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.</text>
            <dbReference type="EC" id="3.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycogen debranching enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="5"/>
    <dbReference type="EC" id="3.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000067">
        <property type="protein sequence ID" value="ODN03632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NEH4"/>
    <dbReference type="OMA" id="YEEGHVH"/>
    <dbReference type="OrthoDB" id="10248904at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11327">
        <property type="entry name" value="AmyAc_Glg_debranch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000070">
        <property type="entry name" value="GDB1p Glycogen debranching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000039">
        <property type="entry name" value="Glycogen debranching enzyme Gdb1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032788">
        <property type="entry name" value="AGL_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029436">
        <property type="entry name" value="AGL_euk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032792">
        <property type="entry name" value="AGL_glucanoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006421">
        <property type="entry name" value="Glycogen_debranch_met"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01531">
        <property type="entry name" value="glyc_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569:SF2">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14701">
        <property type="entry name" value="hDGE_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14702">
        <property type="entry name" value="hGDE_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14699">
        <property type="entry name" value="hGDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Eukaryotic glycogen debranching enzyme N-terminal" evidence="18">
        <location>
            <begin position="106"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme glucanotransferase" evidence="19">
        <location>
            <begin position="195"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme central" evidence="20">
        <location>
            <begin position="813"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme C-terminal" evidence="17">
        <location>
            <begin position="1199"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="1661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF14699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODN03632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1661" mass="187062" checksum="C0E6450AE1C99FA3" modified="2016-11-30" version="1" fragment="single">MMKTVTVISSSSIIKVSVVSSFSSSAVGCSWMISSGALMNQLKIISTTRGRSPKDKDDDMYMCFGLVRRLGIMGSTSGNSGEVRVIQLEETNLEGTVYRVEKGTVLQFRLSSSLHGCQVTLQTNHPLTAGVKFCRSKYYKVGWILDRQNEETYTNLTANIAGNFQYRFTKDGVDAGSGYFIVDPVLRVGSANTVLKLDSISCQTHLSKSLGDFATWKIRLEVAHRSGYNMVHFTPIQELGGSNSAYSIANQNALNPIFGSVTFDQVGKLIEEMKTEWEMLSICDLVLNHTANETPWLKTNPESCYNLENSPHLRPAYILETILYQFSHDIAQGKYVSKGLPAAVKTEEHLLIARQILHEIVPQFKLEEMFMVDVEETLKEFKKKLQSLNPRTNSQDGDESKLTIVQDTLYRRLKSTVDLDVASSVYFYKRQEEDINVGIDRALERLRIKLIQLNDGAKHVFKSHLTSAIDNILAGARYERLQNDGPLLAEVSEENPLIHRYFLKVGLPDREPLETEELLTFGENCRFVLAHNGWVMNDDPLRNFAESDSNVYLRRELIPWSDSCKLRYSLMEYIEFITKHMTGQVIIQKFGEKPSDCPFLWDTMKKYVETTASIFAGVRLDNCHSTPIHVAEYFLDVARNAKPDLYVVAELFTNSDWKDNIFVNRLGITSLIRELNDKHKQVQVNQLFCVISNPEAMSAWDSHEEGRLVFRYGGIPVGAFHQEKVRPMTPCIAHALFMDVTHDNPSPIEKRSVYDVLPTAALVSMASCATGSNRGLDELIPHHIHVVHEKRFYTNFVPTQGKTGNGLVNDSTGIITARRSLNNLHSRLGAVGFTEVYVDQMETDIVAVTRHNPRTHERIVLVAYTVFGYPDQHFKRCGGIKDLIFEGELSEVVLEAQLKPIDSTKGTYPRPGDFVEHPIFLNGLVDFVCDVRENISVDKSQFVTLEGNAVKFTNFQPGSIVIFKILPPSSIVKALESLRSLLAPESVKKVTDSLSLRDLNKVLYRCEEEEKEDTGYGAYDIPNFGKLVYCGLQGINSVMMSGIRSGNDLGHPVCDNLRGGNWIMDYIAGRLLKDDNTKALGNFLQGCFQNVAEFPRYLVPTYFDDVLKIVCFACLESAFSKMSKFVQISSPFTQSLALGSVQCCGISKSGPLPHLSPCLAEPKPFTVQSDNGLVQDCVTMAAVTNELLKSCFLFHVNIKRINYLTGLTHFSTGYMRNWGRDTFISLPGLLLVTGRFQDARYHILSYASVLRHGLIPNLLDRGTSSRYNCRDATWFWLQSIKKYVTSVPRGETLLKDRVSRMWPNDFGESVLDHSVEQCLEDVMQEALQKHFEGISFRERNAGLKIDAHMTDEGFNVTAGVNLETGFVYGGNARNCGTWMDKMGSSEKAGNKGIPATPRDGSAVELTGLCASVVKFLAEMNSAGKYRYNSVERKSSTGQVVRWTFDEWYEKIRENFELHYWIPETAEKSATINNSLVNRRGIYKDSVGATAEYCDYQLRPNFLVAMAVAPELFTPQNAHKALNNVSNILLSVLGMRTLDPSDWNYDGNYDNSNDSSDRKVAHGFNYHNGPEWLWPVGCYLHAYLKISSKLGEVELREAVKHIRKVMSNHWSYIQQSMWKSLPELTNKNGSECWGSCRVQAWSVATLLEVQLELSSILKERSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFN7</accession>
    <name>A0A1D2NFN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein SON</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02689</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFN7"/>
    <dbReference type="STRING" id="48709.A0A1D2NFN7"/>
    <dbReference type="OMA" id="AYPDPMA"/>
    <dbReference type="OrthoDB" id="786951at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19870">
        <property type="entry name" value="DSRM_SON-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032922">
        <property type="entry name" value="SON"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528:SF1">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14709">
        <property type="entry name" value="DND1_DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="4">
        <location>
            <begin position="523"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="3">
        <location>
            <begin position="596"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="726" mass="78150" checksum="34B9BAEBD68EF799" modified="2016-11-30" version="1">MQTPPGSNRRGNRALLPLPLRPSTSSTPRTDGCRTRSGDPRTSQTRGKRLGRGHHLAPRSPRPPRFLPAPLLPHVSRVPRAAPPPPHGTREPPPTRTLISDRASITTTRPPPTLRPHPREQGPRYPPALAVALVPSETRTTRGVAWPGPLRSRGRVTRYHMLLARTDNRSPHPVPSPLSGSPSARSPPTSDPAPVPHPHPPDDHSIAQGAELAPDSHLPRPTSPSPAPFPYSRSPRAPPPPAPAAAQVVAVEAPPAPPAGRGARARGPPRPRAPRGRAGDGRDGPGGDARCVPESLLKCVGRLAKRDALGDARSSDEEDDRFIHHPFHVKDKPLPTITLNIRNAVPLPVRTPHELAIESAKLRTVFPVSSGTQHRFKEIEWKPVEEDKKSTEIVPLEGGSPAPTLSNVATVAPMMREEVQESSSSTEPLAIEAPPDNISVDPPSMPDVDISSVIGLRLKAMRALQENPECNDAKKQLLNATSLMKSWADAKALEPKFLTPAELSSGPQAWAKRDQLRKTTKLDSGMGMHLLQKMGWRPGEGLGKNKEGQLEPLALDVKTDKKGLTAAVEELMFGGKKSGGTSGPSMPVVYDLSGKHPVSALMELTAKRRWGAPEFEMCFEHGPPHKRQFVYKVIVNGVEYQPCVAVGNKKQAKANAAAFCLQSLGLLPTGSVQANELLQTVQKDESDTPIPEGTVNALGSSFNSTPAFLQTVKTDDQLMPPPKLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHL4</accession>
    <name>A0A1D2NHL4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polyadenylate-binding protein-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHL4"/>
    <dbReference type="STRING" id="48709.A0A1D2NHL4"/>
    <dbReference type="OMA" id="PNFCYSG"/>
    <dbReference type="OrthoDB" id="8171816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008494">
        <property type="term" value="F:translation activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051367">
        <property type="entry name" value="mRNA_TranslReg/HistoneTransl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23254">
        <property type="entry name" value="EIF4G DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23254:SF15">
        <property type="entry name" value="POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="MIF4G" evidence="5">
        <location>
            <begin position="302"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="185"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="185"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="565" mass="61737" checksum="0CF42F7F5FB87172" modified="2016-11-30" version="1">MSEAWCDSDATSDKSIGQLGGGKETDSDLLDLTFDPTSDTAPSALRQPNLNEAQLHAALQLGFSGKFLPSSVTGGGGGALLAQGSSASNCNKSASSKGPSASMINNTANLNSSSSQLSGSQNQYPLFVDNYSYNLSEQEQEGLLPPLRRPDINQLPPDVLAVLLKSTRFEEILIPAQRRITDFSPTGAAQVTSASVNPQRTTGLEQETSTSGSGATVTPTPSNKSSTPQSNEDSDTSKKTGFSPFAKEFVPMSFQQRNNMNPQQETVDLAYAMSQVHVQGQNESFQGLVEELDGSDCILSTVTDMISQVTKDPASLNRCAKGVVDVLKKHLNDEDTLGIVVTLLVEQMISNPNFCYSGAKILEILRENKIGVGKSSIKPLLLTRMQEEFTHCLNNLDDPSVRERSLGMLRLLSELYMNFSVLPGQSKLQIFALAVLELMQKLLSKDHSLDVLIGWEVENSEFEKVRECFNLVMKELSYLRMITEGLHPTSKSLVDMIFKLRANKWNRGQDEPTPAAPEPSASKIPVYYEIPDSDDDFDEETGIMIDDEPDDVQAAYEEFLKMSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJE6</accession>
    <name>A0A1D2NJE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stereocilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJE6"/>
    <dbReference type="STRING" id="48709.A0A1D2NJE6"/>
    <dbReference type="OrthoDB" id="8195838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="258" mass="28137" checksum="16B67142C758461A" modified="2016-11-30" version="1">MGGKRDGRVARKSRISLKALAEKFNQDNRIFPGFSEGIARPENLRIVVMSLGNVICGLTDKIVNSIFETDASLFIDTSRILGRLEGCSNEVLSTLAAHAVRPSNYGPPRLWSQEDVETVGVVFAGLKPDAITTIPADAMQGLTPLAIKNLPPTGLLSFTTEQLSKMSFSAAMALTPSQLNNLTPAELEAVRAVLQVQPALFNVPVVADDHQSNANQDLVARDIPTGDENTTDIHGRYRDDIQPNHSSSRSGRYRCRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJK1</accession>
    <name>A0A1D2NJK1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 28 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01545</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex, a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ESCRT-I complex (endosomal sorting complex required for transport I).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJK1"/>
    <dbReference type="STRING" id="48709.A0A1D2NJK1"/>
    <dbReference type="OMA" id="CDEFPTV"/>
    <dbReference type="OrthoDB" id="2671at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.200:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 7 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="10">
        <location>
            <begin position="15"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="9">
        <location>
            <begin position="127"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00056039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="226" mass="26166" checksum="0BF7371D049F340D" modified="2016-11-30" version="1">MFAGLNSGNQGPPQNYDNRPELYEEVKLYRNAWEREKLDNMSDLFSILTTLQQLEKAYIRDCVTPKEYTAACSKLLVQYKSAIKLVQGHEDCPNIEAFIKKFKIDCHAALQRIKEDRPITFKDDKGNTSKCIADIVALFITLMDKVRLEMRAMDQLQPDLRDLMDTMNRLTLVPGDFEGKQKMQAWIDTFSTMSASDELDDDQARQLTHDLEVSYNAFNRLLHQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJK8</accession>
    <name>A0A1D2NJK8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenomatous polyposis coli protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01274</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenomatous polyposis coli (APC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NJK8"/>
    <dbReference type="OMA" id="HCYEILL"/>
    <dbReference type="OrthoDB" id="5918429at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030877">
        <property type="term" value="C:beta-catenin destruction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045295">
        <property type="term" value="F:gamma-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001708">
        <property type="term" value="P:cell fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007026">
        <property type="term" value="P:negative regulation of microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007389">
        <property type="term" value="P:pattern specification process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026818">
        <property type="entry name" value="Apc_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041257">
        <property type="entry name" value="APC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009223">
        <property type="entry name" value="APC_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12607">
        <property type="entry name" value="ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12607:SF12">
        <property type="entry name" value="APC-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05923">
        <property type="entry name" value="APC_r"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18797">
        <property type="entry name" value="APC_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="repeat" description="ARM" evidence="3">
        <location>
            <begin position="505"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="556"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="703"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="783"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="893"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="941"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1053"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1162"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1226"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1323"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1720"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2065"/>
            <end position="2089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2140"/>
            <end position="2177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2200"/>
            <end position="2248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="590"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="704"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="799"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="819"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="893"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1164"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1178"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1226"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1239"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1262"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1323"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1382"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1403"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1429"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1720"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1736"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1759"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1792"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1829"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1861"/>
            <end position="1884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2000"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2156"/>
            <end position="2170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2214"/>
            <end position="2231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2232"/>
            <end position="2248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2248" mass="243828" checksum="6F115B9FDBA9EA3B" modified="2016-11-30" version="1">MSNNGRNSPQSWRPSASSNSKGIEGSDRLAGQVHGPPIHHHHHQQQQQQHHHRERLDRDRDKNHETVCNLLSMLTLGMDQQQEASTSSSGGGSGNTAALDHTRMLLLNLTNSPESCIALRRAGCIPLLIDILHPPPSPPLGMKPPEIIKTRAAKALKNIVQFNPDEKLKRKELRVLKLLEGIRAFSEAVRLALQALGKDIKSFNIGCEGNVAATETTEDPKLDDPNIQDKLRQTQQHPTANMTTLMKLSFDEEHRNIMCLLGAIHALADLIVCDHLIHGNSPSEIKDDCLLIRRYSGMTLTNLTFGDGTNKALLCGMRDFMQALVSQLDCENEDVCQVTASVLRNLSWHADSTSRASLRDSNAVPKLTLAAIKSSKESTLKATLSALWNLSAHSVSNKGAICTASPDALPFLISLLRPNNPILKTLKTPMIIIENAGGILRNVSSQICSSPELRKILRDNHCYEILLEHLKSCSLTVVSNACGTLWNLSGGVGCEEDQRKLLDLNAVPMLKNLIYSKHERISQGASAALRNLLSSRFAKEHMLQLDSRLTAQIYSPNTAHTTDRGTCVDSNQESPGSDGDFDFEFNGNVHQPHSQYQQQQQQQQPQIVHHRPSVHQEPPLAHQQSSAAAASIFHRIHVQPAHTVTAPPHFHPQSNFAHPGNYMNRPTSINYSIEPEPLDLTLTSAKSSPIHIISAAEFGGMTGHHQHLHHSHPHHRKPKPSPFSHNNTQTQCHNNPKPFYNPPSLLHQTGSASQCNSPMRFAYPGAKFNQSCPEILSRLNSGHPQINNFVPEQKPLDFSSNSPSASSSLRGAGEAAGTHNDSANGGDTTFNYSLQYTEEDDEYRVANAGNGESAAKSEDTLKTYCYEGTPHNFSISNSCQDLVQEIEFEKNNPATASASEKPSANNANKSPKLQPIDEAPKSYYVENTPAVFSRTSSLSSINSSGGLNAGENKAEPLGADCQSPQTSIDKKTGCVDESPSSAFHQAQNKRRNNTSQGILAPGRVTFSAEETPLMFSRCSSVASLDSLDVGVIGSGGGKGLASHNDDDLSDFSRRASEVVSPSDLPDSPRAMTPPVRLYEQPIHGRDKVDAPEKQEGDDDLKVFSVEEKSGLNSCRSLSPLMIDGEVLPILSKRKLEPEQGYLDKRDVGSTAATADKATMRSIAVNESQLTSNGNSETKPSDGHEKKKAAFPDDEVKIFAMEGTPFYGVSNATSLSDLTMDLDNMEQKPEVEQQCKPIEESSNPQTKQSETNVATVQADHPPQNAQNSSCETNPKPEEPIYSDVQLLQKCIRIGKTVGIPKSKSEYKITNDGNMGILAIASNTSGSTSNLTSSSGGSNFKKPLVESKSQQDFDDPDLAALIMKGRNRPKEKERISSKGSKPLKKSDKEDMNSKSFSEHDAPKQSPDQKSTDSEQTNPKPEVEVIVVENRVPSEDEKSSDSCDPNPSEVSKLDNVVSMNKTELKIETQQLDPSQISTTSLGSEWNDETPTFSSPIPSMSISTAFKIVGGGDDSSCSKAPVINNQTKIQSSMNSSMLTMSVNNEWLDNVDPPSTFSNLVSSSDCILMGSPPLNPKLQGSMSDKLSRKWKALEAGNTSSIHSNLSGQRPPLDLDLENSMISVASIKSEIYELSSTASFTNDVFQSAVEDICSPVAERITADNSIGGNTYTIFPPENMNAENGKSTDIVSEGGNTVVSDDFTDAEEIEDFETAPADDHIDHIVKPEKGDVEKTDTGKPEEVDNEGNVENDEIEAHIEKATPPSNLILQPQQQQQINQQKPLMEVHPLESGTKYSTFKVSRSPMSPRSSPKQKRRDDPERYKTRTIAALHAGRSLLQSNDSNGNPLESDSRFATFRVGGPKIAKPVQNVNTNTPSVKSSQSNSPDSTPGNSPKGIRGRRKPLYSSLPPSAIVKKRVAPPVPPKPVRQASPVRPPSGGSGVYVRPTRTSELRIAANSRDNSPGRLASSRTSSSSSLNMAPTPLPRQSDQESIVSCRPKVAPKPPVRTTASVSSASNVKPFSGSTVLIKTSNSSFGFGQQKVADGSFAQNMKGYSTLPKSSKLGGDFSGMYLPGSVPDSRNAESKESIPGSEKSQGKMGKLTNLFKKMDFHRSSRESNETLQHVENKQCDILGNNGVEKKSSRLSNFFGRKKDKTQPKPFLDSNGGSNANMGPSNNASIRGPSGIWIRRDGENKAMVAPFNYVPPPGHSITSGVTQHNKDQNSVVSSNNSNANVPAENVLQASNSSAAGSAKITTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJL7</accession>
    <name>A0A1D2NJL7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Sodium/potassium-transporting ATPase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_01290</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.</text>
    </comment>
    <comment type="subunit">
        <text evidence="19">The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 20">Cell membrane</location>
            <topology evidence="1 20">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 20">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJL7"/>
    <dbReference type="STRING" id="48709.A0A1D2NJL7"/>
    <dbReference type="OMA" id="QEVHLGH"/>
    <dbReference type="OrthoDB" id="158672at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000038">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000003">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005775">
        <property type="entry name" value="P-type_ATPase_IIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01106">
        <property type="entry name" value="ATPase-IIC_X-K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF13">
        <property type="entry name" value="SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15 20" id="KW-0406">Ion transport</keyword>
    <keyword evidence="16 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11 20" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 20" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="7" id="KW-0740">Sodium/potassium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 20" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="900"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="967"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="996"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1033"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="22">
        <location>
            <begin position="72"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00037422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00038795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODN05419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1072" mass="119342" checksum="8366EF9DE6758557" modified="2016-11-30" version="1">MCENNRVWAPNRRRSSAVSRASMLVARKSNVGLENPSFIADDQLPMQEVHLGHSKDIRRKSITYLKKELEIDYHEVDIGTLYNRYGSHPDSGLSEDQVRRNREKYGINQLTPPKKEPTWLKFIKTLVGGFQLLLWVGGILSLIAYVTQYIQTGDPPPDNLYLGVVLIVLVIVLGLFTFYQEYSSGKIMESFSKMVPSYANVIREKKLQSINATDLVVGDIVEVKFGDRIPADIRIIECSGFKVDNSSLTGESEPQSRSPQCTDENPMESKNLAYFSTNALEGTAKGIVVATGDGTFIGRIAGLATGLDSLETPMSREVTHFVIFISGVAVFFGVTFFIIALSMGYEIIAAAIFLIGIIVANVPEGEGGSKLISKSFTHISGLTRLIMLPTGLLVTFTVVLALTAKRMADKNCLVKQLHAVETLGSCSVICSDKTGTLTQNKMTVSHLWFGNKIVSAEIGSKDFEKDESGFISLARVATLCSRAKILPDQDNIPIAERKVNGDASESAIIRYMAQMIGNIEDYQEKRKKIFEVPFNSVNKWQLSIHDLNQQNEPRYLGAPERIISLCTKIAINDTVYDLDERWKKTFNDIYEEIGGMGERVIGFCEMMLPADKYPKGFQFDPDNLEFLKDGMTFQGLVSMIDPPRPGVAEAVQTCRTAGIKVVMVTGDHPITAKAIARSVGIIAPHNETVEDVAKRLKVDVEEVDPTQCTAAVISGTELMEMSTPELDEVLKHHTEIVFARVSPQQKLVIVEGFQRLGKIVAVTGDGVNDSPALKKADIGVAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKCICYLLAANIAELCPFLFYIVLGIPLALGTIPMLVICLGTDILPTISLSYEKAEGDIMKRPARNPDTDKLVTGQLISYSYGQLGVIESAAGFFAYFVVYAQNGFLPQTLLGIQTRWDSITINDLEDSYRQEWTYYDRKQLEKTGWTAYFCAVVVCQWANVLISKCRRVPLHTKLFDNWVVFAAIFGETLLACFLSYTPGLNTAMSYMPLKIWWWLPGLPFFLVILLYDEARRFLLRNCPKMLWFQREFYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK70</accession>
    <name>A0A1D2NK70_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alanine--glyoxylate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2-aminoethyl)phosphonate + pyruvate = phosphonoacetaldehyde + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:17021"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57418"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58383"/>
            <dbReference type="EC" id="2.6.1.37"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>glyoxylate + L-alanine = glycine + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:24248"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="2.6.1.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK70"/>
    <dbReference type="STRING" id="48709.A0A1D2NK70"/>
    <dbReference type="OMA" id="IHCETST"/>
    <dbReference type="OrthoDB" id="7403325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047304">
        <property type="term" value="F:2-aminoethylphosphonate-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019700">
        <property type="term" value="P:organic phosphonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01376">
        <property type="entry name" value="PhnW_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012703">
        <property type="entry name" value="NH2EtPonate_pyrv_transaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03301">
        <property type="entry name" value="PhnW-AepZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010006">
        <property type="entry name" value="PRK13479.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42778">
        <property type="entry name" value="2-AMINOETHYLPHOSPHONATE--PYRUVATE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42778:SF1">
        <property type="entry name" value="2-AMINOETHYLPHOSPHONATE--PYRUVATE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5 11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="10">
        <location>
            <begin position="29"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="378" mass="41884" checksum="DB48588A11047473" modified="2016-11-30" version="1">MTNQATPQEKKLFTPGPLCVSPTVKQALCRDMGSRDTEFIEIIKNLRDTLVNIAGLPRDEFTTVIMQGSGTYTVESVLLSTSNREQKVLIIANGAYGQRMKTICERAQIPFDILSFPETQQVNVEDVLKFLESPQSAGLFGSVAVVHCETTTGIVNPIENLGEQLKKKFPTMTYIVDAMSSFAGMETNYSQVDFLVSSANKCLQGIPGFGFVICRIAALEKCKGLAKSLALDIYEQWKGLEQNGQFRFTPPTHAILGLRQACKELEAEGGVAGRARRYKQNSEVIKAGMAQRGFKQLIKEHDGHIITSYFCPAHENFDFQKFYDGLSDLGQLIYPGKVTSADGFRVGHIGHLNAEDMEHLLKCIDQVLQDMDIPCPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKQ4</accession>
    <name>A0A1D2NKQ4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear cap-binding protein subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">20 kDa nuclear cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00823</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear cap-binding complex (CBC), a heterodimer composed of Cbp80 and Cbp20 that interacts with m7GpppG-capped RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the RRM NCBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000015">
        <property type="protein sequence ID" value="ODN05853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKQ4"/>
    <dbReference type="STRING" id="48709.A0A1D2NKQ4"/>
    <dbReference type="OMA" id="DIRRIIM"/>
    <dbReference type="OrthoDB" id="201398at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031053">
        <property type="term" value="P:primary miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12240">
        <property type="entry name" value="RRM_NCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000128">
        <property type="entry name" value="Nuclear cap-binding protein subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027157">
        <property type="entry name" value="NCBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034148">
        <property type="entry name" value="NCBP2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847">
        <property type="entry name" value="20 KD NUCLEAR CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0943">RNA-mediated gene silencing</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="18210" checksum="F4BB12A5D8805164" modified="2016-11-30" version="1">MTKVFTDRMNSKLSDYRDQLFKGSETDRERKLLTSSTLYIGNLSFYTREYQIHELFSKCGDVRRVIMGLDRFKKTPCGFCFVEYYHREDAENAMRFVNGTRLDDRVVRTDWDAGFEEGRQYGRGKTGGQVRDEFRKDYDAGRGGYGKMFGHVELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLB6</accession>
    <name>A0A1D2NLB6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLB6"/>
    <dbReference type="STRING" id="48709.A0A1D2NLB6"/>
    <dbReference type="OMA" id="VESYENH"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905710" evidence="1">
        <location>
            <begin position="20"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="109"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="32240" checksum="0D57FC005170EBE9" modified="2016-11-30" version="1">MNLITICAVLLLFIGYHEFVVDGVAVEIDLRLTDKQKKIMDKFKQIMIPKLPHNYMKEEIYLVRWLRATDFDLKKSEEFLLQNLKWRKQQKMDVIHKEDWSDMQHDFPYYIDVVDKKGQPVITAISRDWDIRNAIVTGRIRRVLRYLDKAMDEANGLVRTFQLEGQNVTQFILILHMGNFNLFQHGCPRCITSILEFVESYENHFPGTADRILLVNTPPAFEPIAQLVREAMTPSTREALKIYGNEPKVWKKLLLDLIDADQLTPEFGGTKSEKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMC4</accession>
    <name>A0A1D2NMC4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Neuropathy target esterase sws</fullName>
            <ecNumber evidence="5">3.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Swiss cheese</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">Ocin01_00203</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain. Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:40807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28610"/>
            <dbReference type="ChEBI" id="CHEBI:30823"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:40808"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>1-hexadecanoyl-sn-glycero-3-phosphate + H2O = sn-glycerol 3-phosphate + hexadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49092"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57518"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:49093"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + hexadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:40435"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:72998"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:40436"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:15178"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with Pka-C3; interaction inhibits the catalytic function of Pka-C3 and the esterase activity of sws.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type III membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NTE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMC4"/>
    <dbReference type="STRING" id="48709.A0A1D2NMC4"/>
    <dbReference type="OMA" id="GQQEDRH"/>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046470">
        <property type="term" value="P:phosphatidylcholine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd07225">
        <property type="entry name" value="Pat_PNPLA6_PNPLA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000010">
        <property type="entry name" value="neuropathy target esterase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000012">
        <property type="entry name" value="neuropathy target esterase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1090.10:FF:000022">
        <property type="entry name" value="Neuropathy target esterase sws"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000022">
        <property type="entry name" value="Patatin like phospholipase domain containing 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001423">
        <property type="entry name" value="LysoPLipase_patatin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF29">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01237">
        <property type="entry name" value="UPF0028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 22" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="14 22" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="24">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="24">
        <location>
            <begin position="434"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="24">
        <location>
            <begin position="532"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="25">
        <location>
            <begin position="853"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="353"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1221"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="22">
        <location>
            <begin position="857"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="22">
        <location>
            <begin position="884"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="22">
        <location>
            <begin position="1006"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="1222"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="22">
        <location>
            <position position="886"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="22">
        <location>
            <position position="1006"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="26">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="ODN06433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1276" mass="142560" checksum="32DB6AE31FB27CE2" modified="2016-11-30" version="1" fragment="single">IIIGTTFLAIAIGILVGICIVRRTRLKHVLPEAVTGGSKTRFRKRDKVLFYGRKMLRKVKNISAGANKRKKIISKITKKLLQIKKDAPPPQLHVLEPAAEYLQEDVSNKGDKLLPPEVTYMLQSIRMFGIFERPLFLELCKHMETCHISAGQYLFRVGDADENFYVVQSGRLNVFITECDGTTITLKLVKEGDSIASLLSFTDVLTGHPQPFKTVSAQALEESVVLKLPVAAFREVFEKYPETFVRVIQIIMVRLNRVTFTALHQHLGLSHELVQAPRRKTLTIGASPLRRNTIHTQHTNDDGIAQTPDLLDSDTSAIHATVTQTLQNEVPVRDIDSLQSVLRKRHSIPVQIGIHPGIPVQGSTGSSGSYDEQQQQHGTSEMDSEVLLREAIVAFRNNLGLEDDSDIRDIIHLRDVPAGAYLTKEESQHLDCGLVLVISGLLTLTQRENDRDVLMFNAHPGEFVGALAVLTGEPSIFTIRAKHHTKVAAMSSSAFYSLMAIKPKIVLHVAHIVVKRLSPFVRQIDFAMDWIFLDGGRALYRQGDESDCTYIVLSGRLRSVITRADGKKQLVGEHGRGDLVGIVETLTSYPRSTTVMAVRDTELAKLPEGLLNAIKLKYPVVLTRLIQLLGHRILGSWQQPLVHGPPKIENKPSHVNFSTVAVLAVTDDVPLSAFTHELIHSLSHIGASLRLTSDYMKQLLGNSILESANEYKLNSWLAQQEDKHRIVLYQCDNTLTVWTQRCIRQADCILIVGLGENEPTIGKVEKQLEHLAFRTQKELVLLHKEGSRPKDTALWLNARTWCSSHHHLQCPKRMFSRKARMPDYYTVVMKSEPNIHSDFSRLARWLTGTSVGLVLGGGGARGAAHVGMLKAIQEAGIPIDMVGGVSIGAFMSGLYAMERNIVTVTQKAREWSKKMTQWWRQALDLTYPVTSMFSGAGFNQTLKDTFGDCQIEDLWLPYFNITTDITSSAMRVHTYGSLWRYTRASMSLSGYMPPLCDPTDGHLLLDGGPLWVYVRASMSIAGVFPPLCDPEDGHLLLDGVYSDMIGADVMRAHGARFILAVDVGSQDETDFTNYGDSLSGWWLLWQRWTSHFRSTTVKVPNLPDIQSRLAYVSCVRQLEEVRNSDYCHYIRPPIDKYKTLQFGSFDEIKDVGYHHGKTYFDGMMKGGSILPLMGGGPQQLPLLQKVASMPKKRTDRPMSATYNFTDLAQMVLKVRSSYVPVTDDDYSDEDTDLPEGYTSEHSLEYYHQSSSMPEKDTNTGGSRAGAYSENDADSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0U1</accession>
    <name>A0A1D2M0U1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA replication complex GINS protein PSF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_20105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GINS3/PSF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008175">
        <property type="protein sequence ID" value="ODM86578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0U1"/>
    <dbReference type="STRING" id="48709.A0A1D2M0U1"/>
    <dbReference type="OrthoDB" id="10251744at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21693">
        <property type="entry name" value="GINS_B_Psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055221">
        <property type="entry name" value="PSF3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22466">
        <property type="entry name" value="PSF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF3 N-terminal" evidence="2">
        <location>
            <begin position="15"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="20038" checksum="5E1081350F57797E" modified="2016-11-30" version="1" fragment="single">MSTKDLRKAYHPNYFSIDSILAAQTLVPCMTQTTIPKFGFLVPDCNSEDLPFGTNLQLPIWAARVLCRPLRTFVAVTIPPGFKEAHGKVTEEDPNIVDLSKVNDNFYEAGHLCTALFHSEAGELAEMLPDVLQARVLCLGSATGTPSPNGTPIKAELMDNVEKKLMEDTQKCRTNVDEWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M137</accession>
    <name>A0A1D2M137_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_20021</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007769">
        <property type="protein sequence ID" value="ODM86663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M137"/>
    <dbReference type="STRING" id="48709.A0A1D2M137"/>
    <dbReference type="OMA" id="MPGRGEQ"/>
    <dbReference type="OrthoDB" id="10045438at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000173">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Histone H2A C-terminal" evidence="14">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM86663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="10540" checksum="7736DF95F021B40C" modified="2016-11-30" version="1">MSGRERGNYAERVGAGAPVYLAAVMEYLALRFSSWPVTLLVTTRRRRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1P5</accession>
    <name>A0A1D2M1P5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BED-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006880">
        <property type="protein sequence ID" value="ODM86886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1P5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="36357" checksum="7C42D70066A6A43C" modified="2016-11-30" version="1">MDFRDKLLSSELRHVTELVNMLSYEVVILQDFLTEEFGRKYKKFRSTHVFASESTQEFAQTRRSASTGIRNLGKSNAGISLRDFRSGKKSRQQEDPLAAEHQNVELPSRKTSKGSIIAEADDDEVDEEFTETKLLVQNAANSSNQNSSSEDEEMDSDSDSNYSEGDGIRRLSWTKDNLEAEASRIGSYHKRIWEYFEWKKLPDGRKIVRCPKCKTRVSAVAKRMQGIVKDVQEKLDNQMQERKELIFLLTVEDIVRSAVKPVTVAAEAPDIPLQRIPSPPVDDFPRTSGKPKGLVWSHFEKFTTPENQIIVNANTAPQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2N2</accession>
    <name>A0A1D2M2N2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005839">
        <property type="protein sequence ID" value="ODM87229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2N2"/>
    <dbReference type="STRING" id="48709.A0A1D2M2N2"/>
    <dbReference type="OMA" id="YERYDIN"/>
    <dbReference type="OrthoDB" id="7280806at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005312">
        <property type="entry name" value="DUF1759"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF5">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03564">
        <property type="entry name" value="DUF1759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1029" mass="116824" checksum="794CA06EF31C783F" modified="2016-11-30" version="1">MDKQVAKQGALKGQFTRLRNTINDPTKPLDAHKIVVHLEKLNELWTKAETLHEKIIDLCPAAAAVSVSSSSSLPNRRVKLPAIELPSFDGNYDQWTSFYDLFTATIDSDSSLLDSEKLKYLKHSVKGDAEKLIRSLTQLLDTTNECLATLRVHGRPTEHWDDVIIYFLQEKFDKETRRHWAMTLTGTKLPTYDDLSTFIEKHIRGLHASTSNQPVIQTHQQRSSHQRRVTTTHYGNVEPKCGICHSDHPIFKCERFNSATVQQRIDLVKKSNLCFNCLRPDHRKPDCNSKSRCKKCKKQHHTSLHIASRSDIPQPLGNDNNGTNAAAGGRSLSTNLAASEYDENQVLLSTAIVKIKDQYGTDQFCRLLLDSGSQATLISENCMNRLGLQRRHSSIRITGITSSSESARGEASMRLYSTVNNKIIDITALVLPRVTGIQPKFECPQREWEHTRGLTLADPLFHKPDSVDILLGADYLSDVWLQGMVNGHSGTPLAQNTIFGWVISGRVSLRPGPSVSINIVETDTDKILRRFWEVEELPWKSTNYNRRKCEEHFRETHSRDDTGRFIVELPFNEKTSQLGYSKQLAVNRLKQVERRLASQPEKRKEYNKFMFEYENLGHMELIPDSESGERVGKTHYLPHHFVLKLDSTTTKFRVVFDGSARSNTGVSLNDCLLVGPVLQDDVLPTHPMARVPSSNQRIPTSNYNLRNSLCSLRINKMPQEVGKENLIKHPEAAQVITEDTFVDDILSGSSTVKDAIFLQQELTEVLSQAQLSLSKWASNSEEFMKSIPSTSEKSSPREALKKPTKRQLLSELAKVFDPLGFHTHSPSVPRCFFKRSGNLKKSIWCLYLPQVQMLQWRLCKPIHHLQIQGSSHQAAIPPEIGTLWCLDVCSTPYERYDINETYLLTSWMDRLNNSASLDSGFLRTLEGVLGNRVAKIQRLLPSEQWRHVCSADNPADLCSRGVSAEELKQSILWWTGPSWLIEEQLPATRSLPEVTGDMEERMKQVLVSQVITDSTLFERFSSWRKLKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3K4</accession>
    <name>A0A1D2M3K4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_19129</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005078">
        <property type="protein sequence ID" value="ODM87553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3K4"/>
    <dbReference type="STRING" id="48709.A0A1D2M3K4"/>
    <dbReference type="OMA" id="RNDAFIP"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM87553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="495" mass="56315" checksum="6271FCA1539A3B0E" modified="2016-11-30" version="1">MVVLLTSETLLITIALFLGFLFYKRSSRDSRYPPGPRSLPLFGNVLQLRKYPLQVLQHLTDKYGPVHSVRLGTQDTVIINDPKLVKELFSHINSTGRSDNPAIYYFGKWNGILNAQGHVWEAQRTFTLRRLRDFGLLKSSHEKVLMEQAEALISFFERHAGKSISGTKLFNGPIINGIWKIVSGESCKWDSEVKPEIMEKAEKLVECVNKFLLLFFAPFLRHVAPKFFGWVDWTNAVDSFSELTRKVIEEHSKQLHPKNPRDFIDDYLVKIRETTDPNSSFYKENGAKNLEAVIGDLFFAGSETTSLTLSFAMLYLILNTEAQRNAQQELDRVVGSSRQVFLSDKPTLPWTEAIVLETLRLSSIAPLGVPHLMLADTMFHGYFLPKDVTVIAGLYTIHHDPKIWGEDVNEFRPERFLNGDKTQVIQNEALVPFSTGRRVCIGEGLAKNTLFLFIANTLKKFNIEPDPVCPVLEVETLSGFIREPKPFKLVLSLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3P9</accession>
    <name>A0A1D2M3P9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid amide hydrolase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005026">
        <property type="protein sequence ID" value="ODM87576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3P9"/>
    <dbReference type="STRING" id="48709.A0A1D2M3P9"/>
    <dbReference type="OMA" id="LAWQEEL"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017064">
        <property type="term" value="F:fatty acid amide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052096">
        <property type="entry name" value="Endocannabinoid_amidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45847">
        <property type="entry name" value="FATTY ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45847:SF6">
        <property type="entry name" value="FATTY ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="62"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="1">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="546" mass="60433" checksum="D879DC6B8A55182A" modified="2016-11-30" version="1">MSGTVNPDLLAKIQRRQQERKESFAKLKISNILDEQAKKIVELPSKELVEQLQSRKLTATQVLTAYTAKALELTERVNCVTEFIPQAPEWASKLDKLPTVAGPLHGIPIAVKEDGDIEGMDSTVGFAKLLYKPMKKHSTLVQILLKLGAVPFCKVNVPQSMFSMGSENPIYGLTLNSINEKMGPGGSSSGSGSIVGGGGALIATGSDSAGSCRIPAMFHGICSMIPSTGRMSDKGVLQCLPGYHSQPDVPGFLAKDTDILALVFKSVLENNIQNDFDPLIAPIPWNETLFSSTKALKIGYYTSLPYFPAFPDVQKTVLKAKHALESVGHQVVHFEMPDSFHYLKTNMDMYSADRGLHFLKMFEGEPVSSCVEGLVNCLRNPEKFWKTGENYTRREAISSFARRLIEEKDISANDEWNMILEKKAIQKEVLEKMDETGIDLILGPAYPFPALVCEDVAKFQSLQDSIVYTMFWNFVNFPAGIVPFGNETGEHNDEYDDEGEPMLKVAKELIKDSAGMPINVQVSARPFKEELVLRVLVELEKLRDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M410</accession>
    <name>A0A1D2M410_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HEAT repeat-containing protein 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004845">
        <property type="protein sequence ID" value="ODM87686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M410"/>
    <dbReference type="STRING" id="48709.A0A1D2M410"/>
    <dbReference type="OrthoDB" id="9904586at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040108">
        <property type="entry name" value="Laa1/Sip1/HEATR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663">
        <property type="entry name" value="HYPOTHETICAL HEAT DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="17825" checksum="FBC329DE0502B6F5" modified="2016-11-30" version="1">MSSANLLFRRSTVDCFHQLSQREAALVSKYFIKQVQLAPEEKQEEYAYYLESGKSGALFKMLDLESDQVIEIGDTMASIFSAAATQDMGQVQVCISLCKNILTYFGDDDADALKLNDELSSAGSKRAQNFSWRSRPFAVECVRKILISSPFILNSNSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M427</accession>
    <name>A0A1D2M427_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004801">
        <property type="protein sequence ID" value="ODM87719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M427"/>
    <dbReference type="STRING" id="48709.A0A1D2M427"/>
    <dbReference type="OMA" id="RCEHEES"/>
    <dbReference type="OrthoDB" id="7743658at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33053:SF9">
        <property type="entry name" value="AGAP000105-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33053">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="29047" checksum="20403E3247792D1E" modified="2016-11-30" version="1" fragment="single">KQSQLHGSLESGLRDWYFRNNIPQKALTDLLKVTTEGKNLPNDSRTFLKTPVNVNIENICGGELYYFVHNDSNLITLQIGIDGIPISNSSSVSFWPILRKCDQLKQPVVFLISLFQGTEKPDNVELYLSKLVDEVKELECKGLVIGDVRKRFKISCLVADAPARCYLKQSKMFNGFHGCERCTTKAYIPAEFARKTRSLKDLKHYKATEYRLFVLFTGIVVLKDIISPEEYEMFFLLQCAVYILLSDNASDPEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M500</accession>
    <name>A0A1D2M500_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Venom metalloproteinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_18691</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004287">
        <property type="protein sequence ID" value="ODM87991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M500"/>
    <dbReference type="STRING" id="48709.A0A1D2M500"/>
    <dbReference type="OMA" id="ANCNQND"/>
    <dbReference type="OrthoDB" id="6497651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="9">
        <location>
            <begin position="12"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM87991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="46611" checksum="6043800333DE2D06" modified="2016-11-30" version="1" fragment="single">MQSSPKAAANDAVAEILVVCDKEFGDIFQHDRVKILDYLTVYFWDINLRYKTLPNINLSFRVTGVVVISTPSGQPFIEEARAPDGRAEFGRILDRFKYWVYQQMSVVPKFDMAVAITNTALEWGGGLAYVNAACKVDNTQKKHVGTLVLNDRGDWGSLTVGAHEMAHTLGAPHDDDPNFPGGVCTWIHNGSDQASCLRAINEPGNPPISPDFSFILAPTKADQCKRKLNNPNAFVSEADIADCKVMKCRIPGDSRIFSFPPVDNSPCGGQSRCFRGRCRMPGSLIRNVGDGRCLQATDPFAFTAPLEPVNCPRNPLDRFVISDDGIGKTLATPWETRDATETGDKCIYTANAEGGIISTDRCSTQPPRNPWHGWDFIDVGNGEFLLSHRITRRCAKPDGVYIRMYANCNQNDRNMRWKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5S5</accession>
    <name>A0A1D2M5S5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Myotubularin-related protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003739">
        <property type="protein sequence ID" value="ODM88340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5S5"/>
    <dbReference type="STRING" id="48709.A0A1D2M5S5"/>
    <dbReference type="OMA" id="WERIYLR"/>
    <dbReference type="OrthoDB" id="271628at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13211">
        <property type="entry name" value="PH-GRAM_MTMR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14536">
        <property type="entry name" value="PTP-MTMR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030564">
        <property type="entry name" value="Myotubularin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010569">
        <property type="entry name" value="Myotubularin-like_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048994">
        <property type="entry name" value="PH-GRAM_MTMR6-9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807:SF73">
        <property type="entry name" value="LD06050P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807">
        <property type="entry name" value="MYOTUBULARIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06602">
        <property type="entry name" value="Myotub-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21098">
        <property type="entry name" value="PH-GRAM_MTMR6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51339">
        <property type="entry name" value="PPASE_MYOTUBULARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myotubularin phosphatase" evidence="4">
        <location>
            <begin position="189"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="610"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM88340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="654" mass="73518" checksum="AD98C040254D1CCB" modified="2016-11-30" version="1">MYSFTAASRTTTKTKRRATSTVPDTWAADDDQQEDVVNQQPIIQLPVPVLVPYRPKTEARRAPAAMEFIELIKAPTVDNVVMRRALFKPIEGTLCITGHHLILSSRKEDSEELWLLHKNIDVVERKLSTFGGGAVVIKCKDFSVINLDINSTDDFTNVADSIEALANIDVPSLSYPFFYRPMYTIVEDGWTAFSTEAEFSQLVLKSEDWRISQVNKDYAVCKSYPATVVVPKSISDEDIVVASSFRQGGRFPILCYRHENGTVLLRSGQPLVGPAGRRCKEDERLINAVLGPGKRGYIIDTRTQTLAQTAKLSGVDVNMVACRGAVVGKAIFDWQSKGGGFELEVYYPQWRRVHKPIDRHHNLLDSLSKLMEACNDTSSTMDKWLSRLESSGWLTNVASVLNCAALIAQSLVQENTSVLVHGSDGTDTTLAVTALTQIILNPDCRSIRGFEALIEREWLQGGYPFGTRHFKSCYAYANSSARNPKKTFAPTFLLFIDCVWQLFTQFPCSFEFTENFLITLVQHSYASQFGTFLCDSVCEREELDLKNKTVSLWSHVNRPEVITSYMNPVYEPNSKVIWPSVAPVSLTLWSGMFLRWVVDQSPTKDTWSTITELKEKEREMKREAIKLRKQLLDMEKAIIAKRASESTATTTASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6H0</accession>
    <name>A0A1D2M6H0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003420">
        <property type="protein sequence ID" value="ODM88577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6H0"/>
    <dbReference type="OrthoDB" id="6359943at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="52"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="10633" checksum="CE41EFD75593B382" modified="2016-11-30" version="1">MPACNTGRDQFEGDVIILLVAESPIDKWTDGNVPLPSALNMNANILKKQIACDFELVSEQGKRFKCHKVFLAVNSPVLARMLETECEEVKHNAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6J1</accession>
    <name>A0A1D2M6J1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003402">
        <property type="protein sequence ID" value="ODM88595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6J1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="16346" checksum="CEFA91361E39A664" modified="2016-11-30" version="1">MLEMDCKETKEKAIKLEMSGKGVEALLKFIYYSNVDDPMEHPRVALELMEVGNQYDILGLEKAMKDIFLGQRYDWFDIDTAVLLYNWTLKVDGNEDLKWKAIQVFKSNLGDLEGSTEFDKLMKEFPQAAKKFIALCFASYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6X9</accession>
    <name>A0A1D2M6X9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translational activator GCN1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_17953</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003268">
        <property type="protein sequence ID" value="ODM88729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2M6X9"/>
    <dbReference type="OMA" id="FLFTNWL"/>
    <dbReference type="OrthoDB" id="5148094at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25801">
        <property type="entry name" value="HEAT_GCN1_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1295"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1463"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1899"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="745"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2556" mass="281194" checksum="7A3CCB965664C67A" modified="2016-11-30" version="1" fragment="single">GPPKPFQAMQELKNIHYLQKHKTKGGTVGNPRNLNALVDKGDYFPRQEEETASIISRIHPKLGDYKFDKVEDCYEDLLRNHVPKETAVVTSPLSKSSLETLKCVSILVSWSQKDKNEDVNSTPLFATLLCRLIYGIHGTRLERRAERVLHTILGQFDDFSRLLKVLEKVDKNLVCLSMVYNWLMFSSKKKGKEDVFNEARTSTMADLYIKEFLMTKVPKEEWIQEKVSAYLLPCIKGAADTILSSISKALLRSPETAIEVVGFTLAGMKPQLSDELAKEMAKKIGPFLGSENEKLREQAYFTSQSLFRHGPGALVEFLELVSPTARGTKSALTSAGKIHVLKLIKSLEVGSEQAGLVIEKCVKVLENDVHEGTLLECMEVIGCWSKGLDPSSPASGSLSTFIINGLKSMKAPPLRLALCRMIAQLFSTGSSQIHQRFLPEIQKSIISSIDKALAQPSLVHNLAEAVSLSVVLISSASSSSIRIEDSICSQLSKMGNHLDSKFLGSCAPSVHLHAAMVLDFLIKNEMGERSSAYYHALVLCLCCPDREIRQKIKEIITETLRKTSTARRGILDGIHAVVKMPEVSPLLKEEMLTYFSKCCSSTNQEDLKALALDLLVPCHEFEPENKKNLWIFCLKKKLRISPKDLLENGSEEFLLNNFVKGFDSKCATKRRILRTLLGVYGGRIMGDVVATAVEILKDPSFLSVSKDDYLIFRTPEGQLYNQEVGGGFGGGDSGSQTNLKRESKVYSFKEQLEELQLRKELEEKRKAEGKQVKYTPKQMEAIKIQLGKESAIRAQVEQLNSKINNGIDVLKLALEEDQENFEFYIKNFSEELISLMKSPVGAVPAVSFWIQMGKTLFSKGSWIGEALAQVSLRQIHPACDLDRNWGEIEPKESVEKILNRVENLEGISNAALSFCYPFFVMAFQHFPKNGKIISSILQIIEKFSSTGLNDADTIPRAKITNFLYGILEKNSTPLAVSTLVSFCKTAQLKNGAEIVFLEPLELDRHLDALKSPVSLSRETSLTCLQFLCENDLDWIASQEKDLLIHLSGSVYRSQFDPVARISEKAKKIQELLVKTLPQEFPTLCSGLQEDILYPVEAVRISASKAIGFLFVNNKNELESLFQYLKTKYDERSELIPPVVDDLGRILKDEVDSWEARSGIGLTMTNIAPLFRPKQAEEGFKWIVTRGLGDRSQKCQGIMLDAALEMVKAHGLPCLHEFISIVEEILEKAEKSEKFDKIREGAVILMGSLAKYLDSSSPENRGKVKGIFSTLLETLQTPSETVQGAVANCLPELMCGAIKEEAESTIKTLLDKMLGSESYGTRRGSAYGLAGVIKGLGILSLKRYGVLTKLEEGLRDKNEYKRREGALMGLELLCSFLGKLFEPYVIHILPHLLQCLGFVREATENTAKVVMSHLSGHGVKLVLPTLTSALNDEESWRTKVGAVELLGRMAYCAPRQLSGCLPMIVPKLIEVFLGDSHNKVQEAAAKALQLIGSVIQNPEVLNLVPVLLEALQDPGKKAGFVYSQFVHVVDPPSLALIMPVVERAFGDRSTENRKLAAKIIGNMYALTDSGDLAPYLESVMPGIKGACWILLVVAAKALRAMAKGMGEERCYLELLPWLMSTLVSEGSAVNRSGAAQGLAEVVEAPEDQEGELPSHVRDGYMMIFIYLPGVLEESVFGEWIGRIISPILRALADETEFVKQSALLAAQRIITGFSGKAVSLLLPELEKKFDPNWRIRHASVQLLGDLLFKISGVSGKMSTESSKNDDDNFGTEQSGKLIKAALGLERRNRVLSALYMGRSDIALLVRVASLHVWKVVVANTPKTLREILPTLFSLRMVAERTLKDLVKKLGEKILVEVIPLLEKGLGEKALATEREGVCRGLCEIMDNCSRDTILGLLDSLIPSLKKGLCDTDSKVRKAAAKAFATLHSAVGSKAVEEIVPFLLKRVGNSGNEGDLALDALGQLLLVKEKAVMPQIVPQLTAQPVNTKALAFLAEMAGDAVSNHLGKILPSLLEVVEQDLENCSRIILTVEKELAVRNLIEDLLETEGNLRRGAVQLLSVFCINSKVDLEPHVVTLLRGLIYLMTETDEKLLGFVAEALEAVVKKLEDKLSQVALVREAVGEVSKGKGRNYILPGLCLPKKGISPLLPIYREGILKGGTDLKEEATLGIGELVKLSSETALKPSVLQITGPLIRILGDRYGPALKWAVLHTLTALLKKVGMALKPFAPQLQTTFLKSANVLSEVWAVRMKAAEGLGQLVKIHGKPDPIFVEILNSLKNCEGVKHDATDILLYTLRSLVENGGGKVEEATRRSVLAATYPHLSGGERTSRVAAGTVGALIGWLPEPDFLAAMNLILADDKDILQRVARTSAMVVALKLAPARLYAEDGENKFKEQILQTVLNILSAENAALVSNGIRACAHIFTFCIKNDVDLPSILIQPFAKTVNSSSNEVKNLVAQAANVVAKDIMPATLPKEVARYLIPALVNGTKEKDPGVRGASESALISILQLKEGDEGCSLTFGRGGRSNLNDVVVNKLRLNLCLEVEGNEPDIDDTLHVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7A7</accession>
    <name>A0A1D2M7A7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003158">
        <property type="protein sequence ID" value="ODM88812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7A7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903566" evidence="1">
        <location>
            <begin position="20"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="57" mass="5944" checksum="A485E132E58F3D74" modified="2016-11-30" version="1">MSRLFALLVLVAVIAVANAQYYGAIMGLGTYGGLGYSNVGYGYGGYSGLGYGAYYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M825</accession>
    <name>A0A1D2M825_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HEAT repeat-containing protein 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002931">
        <property type="protein sequence ID" value="ODM89081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M825"/>
    <dbReference type="STRING" id="48709.A0A1D2M825"/>
    <dbReference type="OMA" id="IEQWALP"/>
    <dbReference type="OrthoDB" id="192608at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040108">
        <property type="entry name" value="Laa1/Sip1/HEATR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663">
        <property type="entry name" value="HYPOTHETICAL HEAT DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="18082" checksum="855FE1D837688E7A" modified="2016-11-30" version="1">MAVRTSAAKCILQMMQSAPFLYTTELESLTSLCFRALDGADYDGRIAIAKLLGIAVSYTQRPPTPGGGKGKGIMITSSSSSSKNSSAKPVSLEECLSILMTGFLRGATSFLKGEIIKGSSGVNREVRVGVTHAYVSFIEQWALPLEKNLEQFTNHVLELVANPKPLPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M856</accession>
    <name>A0A1D2M856_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger and SCAN domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17516</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002843">
        <property type="protein sequence ID" value="ODM89166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M856"/>
    <dbReference type="STRING" id="48709.A0A1D2M856"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="193"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="510"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="651" mass="73492" checksum="ED0F792DA4AC1A87" modified="2016-11-30" version="1">MKLRNRNKSVKTPPETANKSNTSNKDGPTVAAALSAVWNTSKSPSASVASSSKTQTPNKTTCLFCPNAVILGDQTNPNVHNVKLYQLLINLCNHLQINNAEIPSQRCNSTRFPFCTNCESMVVQLWKQQQILEQVLLKIEKLVGDIEYAVVDGEILDRGRRPGSSSMAQAERLKFTKLRRLILDGYRQKLVRRHEQENAEAGNETDSMNDTETELTSSAAADVKQERFEQQSENFTISTDSTQFESPMEEEDELPPSLIRQDIGDPYESYDESQHHSYSDTADSPDDYGWTGDANYSNTNCTMVITNENAETDVTHLIQIKQETHTLATDQYDDDDDDEAGPDIFALEERKRRFLFEGVEIYRASGTGARSKMDYLQCSLCSYSLPIQKHYTSKVSSPYMKMKTHILHVHKKKTGLPKQPRARELSCIPCSKKFSNLKELREHKATHPADGSFECDICRKPFKKGSSQYNLLIHKFSHKNDEERKISLAANERGAYNSMLSAKLSMAYLAGRGRSEPKKRNRKKGKSQPEPIPAPATPITNDTIEDDSGDHTCTVCSRSFRRKCHLIRHMNTHVQLEEQNNISLRRRRQTTENRGTPQVRAAPVLVSNREPSTSRVNLSENTSTDRGQRVAVGDGTVVIVKREVLELLMNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M862</accession>
    <name>A0A1D2M862_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Importin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17507</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the importin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002838">
        <property type="protein sequence ID" value="ODM89177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M862"/>
    <dbReference type="STRING" id="48709.A0A1D2M862"/>
    <dbReference type="OMA" id="WVAKTSW"/>
    <dbReference type="OrthoDB" id="760868at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000813">
        <property type="entry name" value="D-Importin 7/RanBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25758">
        <property type="entry name" value="TPR_IPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="22"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="933"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="936"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1057" mass="120564" checksum="CCFE7945B4DC1795" modified="2016-11-30" version="1">METRKILELFRATLDPNQRQAAEEQLKQIEKIIGVAPALLQIVMGQEIEMPARQAGAIYLKNLIQKSWAEPDEDEEPRFHIHEQDRALIRDSLVDAVVHAPPIIRSQLCVCIGVICKHDFPGRWPSLVDKIVVYLQSPDAGGWPGAISALLALVKVFEYRKGTERAPLDEAMNLLLPLVQQIMERLMPNVSQSGLMMQRLVLKMFFALTQHYLPLPLLGNKGQWERFRGWMEVVRQVLDRSQPELEKKPEDEDERDELEKNEWWKTKKWAMRILYRMFERYGSPGGVTKEYKDFAQYYLNTYSQGALEVVFKIMNAYRQGNFVAEKVLRDAILYLRNAVSHAHSWKFMKPHANAMLTDVIFPLMCHTEDDERLWKDDPIEYIRSRYDAIDADTAVTCGEQLLNAMCKKRKGVLPTCIQLVTQLLNDPATSPQRKDGALHIVGAIADILLKKDQYKEQFDDVLIRYVFPSMTAPFPFLRARAAWLISKLSNLKFNRDEVLQEVVRVLIAALLNKDEELPVKVEAAFAIEAFVTDQHRTHQYFQQHIGTLCLELLQILRSTENDDLTNVLQKLVCAFVNEVAPLANSICVHLAQTFSQIMDGAGDTEGEKTIVAMGLLNTMETILVVMEEQPEVCLQLEPILLQVVTVILDKSIMEFYEEAFSLIASLTEKHITPAMWQVFEGLYRVIERDGTEFFVELMPALHNYITVDTEAFLQDPNRLLAICTVIKKVLMDDSAEVGEEAECHAAKLIEVLILQCRHRIQNVIPSLLQLALERLAKTIKTSELRTMCLQVVVASLYHDINLTLSVVSSMDAFVKQWIADTDCFLGLHDRKICVLGLCALLQSQNKPAALQECSKEILPSLILLFDGLKRAYAAKALENAETDSEEEEEDDEYCEVEEVLSTDEDEIDEEGAEYLETLERKVKTTQSPFPMTAQIVDDEDEDDDDDDDDDYSTGEETALECYATPLDDEECPVDEYIIFKDVLINLERNDPTWYTALTNSLNEDQRKSVQEIFTLADQRKAAAESKEILKRGGYEFRQQDVPSSFNFGNGNLPPTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8T7</accession>
    <name>A0A1D2M8T7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002684">
        <property type="protein sequence ID" value="ODM89385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8T7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="69" mass="7593" checksum="3E07C5BC71E74703" modified="2016-11-30" version="1">MNLSSVIGVFQLLTAFVGVPLHLYYIYNFSWWGDIGFPAFVLAILVGAVLVFGFSLIGNLFFTSEDGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9R7</accession>
    <name>A0A1D2M9R7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein giant-lens</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002488">
        <property type="protein sequence ID" value="ODM89634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9R7"/>
    <dbReference type="OMA" id="CFCPPLY"/>
    <dbReference type="OrthoDB" id="121932at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.160">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="39855" checksum="1DCD1554BCE0817C" modified="2016-11-30" version="1">MGLGESYGERVLRVSQVSAIIFLCQVSCIIHAQRDSATTKTSPSNYKDAVFVYPTGIRSERDLPVCPSFIEEENKDMSTGSSSGLSNPLYIGSDMNKLQQPGSTRNPADSKKTEYPSKYLSACNIIHRRYFYPPIVERLCRCPDRTECPMEWSQPPKYKDLFVDTKGAKSSVSTTPSTKSATTMDPYTVMVSSRSQLKFCTEVATNLPDCEGTSKHNKEHIDDIVSMVKTVRKTFIAPELPIVTVNCFCPPLYRRWKFMSKNETTERGNNGTAETNYNYRCDKMRRCKTDQQCGTVRTDLHFSYYHCSCPKEHLCVPKVYPPVSTSHVVDHAEEALFSGQVAPAFCTPERVAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB56</accession>
    <name>A0A1D2MB56_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002136">
        <property type="protein sequence ID" value="ODM90159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB56"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="85" mass="10075" checksum="C6BD62B9021906DD" modified="2016-11-30" version="1">MALKFPKVSTIAVFCFYTMCSLILDNFFAIYYQYGYGRYRPEYWCIEESDEVKDEDFPSKLKTCDTEIGLLEAYTISFAHLLPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB64</accession>
    <name>A0A1D2MB64_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002142">
        <property type="protein sequence ID" value="ODM90151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB64"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.15.10">
        <property type="entry name" value="Proaerolysin, chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56973">
        <property type="entry name" value="Aerolisin/ETX pore-forming domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="444" mass="49930" checksum="1FF202CCD0E9F229" modified="2016-11-30" version="1">MSVHFDSFLFYCESTVFEEPDFKGYMYEGSTNGGCTDVPDPSRNCIGSMKTTDCIVIYEYTQCHGRSDKHNGYGIVITSDEHNFTSRNFERLHRLSKIASFRDCTQLEKDSQVHLDFYDGHFLPFLTYRNVCTCTLLPNAIRHSADTVTLNLLLYGKCVNLHYEDNCNDKPFQIGKYGETGNVDTGSYQSFKPCKLPQHCVIMNAVLTQLEPLNDIINLQNLTNTVTIGATETFRNNGGGTLEEDYSVEKDIEENFQFGFAKEFSQMNSISFDVGVKIGVKSSFMGGLVSASAEIQEGLSTKYQSTSSSTETKEYGVKRTTKFKVDKKVIIPPCTEYKVGSTVQVAKDVEIDYRVEYKITGFIQPNIKMKSTEIRAYLGGMKYIKDVDEFTVLAETTALMKATFGLETFADAKGAIIAPCLKVNKQLMYKPRGTLMHLNNSFMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBQ2</accession>
    <name>A0A1D2MBQ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Calcitonin-like peptide type 1 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_16269</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001981">
        <property type="protein sequence ID" value="ODM90415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBQ2"/>
    <dbReference type="STRING" id="48709.A0A1D2MBQ2"/>
    <dbReference type="OMA" id="ATATYHC"/>
    <dbReference type="OrthoDB" id="6160250at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004948">
        <property type="term" value="F:calcitonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050332">
        <property type="entry name" value="GPCR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003287">
        <property type="entry name" value="GPCR_2_calcitonin_rcpt_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001879">
        <property type="entry name" value="GPCR_2_extracellular_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017983">
        <property type="entry name" value="GPCR_2_secretin-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620:SF32">
        <property type="entry name" value="DIURETIC HORMONE 31 RECEPTOR, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620">
        <property type="entry name" value="PDF RECEPTOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02793">
        <property type="entry name" value="HRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01350">
        <property type="entry name" value="CTRFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00008">
        <property type="entry name" value="HormR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111418">
        <property type="entry name" value="Hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00649">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00650">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50227">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 17" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 1" evidence="15">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="16">
        <location>
            <begin position="120"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM90415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="384" mass="43874" checksum="2267EAE2209458A0" modified="2016-11-30" version="1">MEKEVSYCPQTFDSWSCWNETPAGETAYAPCPWFVPGFEPSKFAYKECLEDGSWFKDSLTNQTWTNYTTCVNIEALLVSNYELKTLWVILRKVLPNVSVVSEVGNTVSVFVLILSLLIYCQFPSLSSPRATIHKHFLASFTIHNSLWLVWYRTVIKVITVDELNEVSTSTYSTSATRSLEGNRNYSKWFYIFGWLGPLIPLGLYAIIRATDADPNETKDCWIQDSKWSLLISVPECICLLACLVIVINIVRVQVMKFRFELSITESVASDRSIRKAALTTLILISLLGLEYVILPFKPDKKSNESEAATYNYVEELTTSLQGLAVSLILCFCKRQVRAIIKRYVCRTKRLQTWFMRTFMTNAKSGETRQNTRSTTMNLVSQNAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC84</accession>
    <name>A0A1D2MC84_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Phosphatidylinositol-4,5-bisphosphate 4-phosphatase</fullName>
            <ecNumber evidence="4 11">3.1.3.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_16129</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:25674"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57795"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="EC" id="3.1.3.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Late endosome membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3 11">Lysosome membrane</location>
            <topology evidence="3 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.78" evidence="4 11"/>
    <dbReference type="EMBL" id="LJIJ01001912">
        <property type="protein sequence ID" value="ODM90549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC84"/>
    <dbReference type="STRING" id="48709.A0A1D2MC84"/>
    <dbReference type="OMA" id="ASNHGGM"/>
    <dbReference type="OrthoDB" id="364348at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030670">
        <property type="term" value="C:phagocytic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034597">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019178">
        <property type="entry name" value="PtdIns-P2-Ptase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21014">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21014:SF6">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09788">
        <property type="entry name" value="Tmemb_55A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0967">Endosome</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0458">Lysosome</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM90549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="25802" checksum="750962F6A9E98552" modified="2016-11-30" version="1">MEEAGESQPLLATTNNRQDQNNSGRAVVLNASDQSILEYVSLPSGSLVTCRVCQASIDITDKREQHVVKCGSCSEATPIRNPPPGKKYVRCPCNCLLICRASSQRIACPRPNCKRIINLAPSPALPAVPLGMARVNCAHCADSFLFNTLNNSLARCPHCRKLSSVGPDFARSRGIFHLVLAFIFLLIGIGVTVGTYQVATRKGGLFVAYLGAFLVALFFFVRTIYYCTMKISTIEGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDX5</accession>
    <name>A0A1D2MDX5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine protease inhibitor Kazal-type 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001635">
        <property type="protein sequence ID" value="ODM91190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDX5"/>
    <dbReference type="STRING" id="48709.A0A1D2MDX5"/>
    <dbReference type="OMA" id="NDYTLTN"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10975">
        <property type="entry name" value="CE4_CDA_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052740">
        <property type="entry name" value="CE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985:SF8">
        <property type="entry name" value="CHITIN DEACETYLASE-LIKE 9, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00282">
        <property type="entry name" value="KAZAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kazal-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="403" mass="46078" checksum="3ED685A69C1B67FF" modified="2016-11-30" version="1">MDCYCTEQYAPVCGTDGKTYSNDCFRKCADRIRQDECILPTCRCSGTDIPGNLSSDKIPQLVFLTFDDAATTQNTNFYREALYNRTNPNGHPISATFFISHEYTNYALVHELYKFGHEIALHSISHKPFVTYWKSLNQSMWEAEIVDQREQIATFAKVPITGIKGMRAPFLQIGGDEMYSALKQADFLWECSRPTFDFRKPGLWPYTNDYQSIQDCRIPPCPVWEYKGFWTVPMIQMLGANGGGCAMADSCTPLPTTADETYNLLLRNFNDQYTTNKAPFGIFLHSSWLVGNSYQEIIARREGYNKFLDFLGNKADVYIVSISQAIEWIKRPTPLEQLANFTPFQVDRKTGDCSNQYTCRYTLEQTSFPIETERYMTGCTPCPPLYPWVKNPLGKEPVASVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME58</accession>
    <name>A0A1D2ME58_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001624">
        <property type="protein sequence ID" value="ODM91223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME58"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="449" mass="52231" checksum="3839BCD1365F1888" modified="2016-11-30" version="1">MREMQTGGTLKKRTRRPVFKGNRFPTVPYNNAGQSEQFLRDNYTSKPSFVGYSDSDTRVNMKSLLARSTVSGDLKNSTRVTRNPLFHLMEDGMTMAYSETLGFDTAGGDQVTKWKHSRPYLLCEAVFTRLRIIVMLGMLSGNVPWRWNNKTKRINRWSSIMFTLWKFYWCLTVIQSLFMLLYHMRCFLGMYSRNLESYRGIFAYSTTLYWYACHLGYRTCMLLYEDDIRKYINRLQDFNEEYSCKYLIYADKGIESGVGRMVMKFSIPAAASQIANSVFLFLITPAAPYYLTSKVKPLRWYHLIPGALQDMTVTGHTIGTYLILSWLQVAHTSSVQFWLREMHKDIDSDYTTEGLRTPEVTIPTYKALQLMCTIYNGFMAACIPVWKFSVAFGFIPCGFLWIRSMNHFFIEEFPVYPFGVLNCFTMAFGYDKPFYADQWAMNVGKTICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEK3</accession>
    <name>A0A1D2MEK3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="9">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15253</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01001548">
        <property type="protein sequence ID" value="ODM91429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEK3"/>
    <dbReference type="STRING" id="48709.A0A1D2MEK3"/>
    <dbReference type="OMA" id="FINMLTI"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008545">
        <property type="term" value="F:JUN kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06616">
        <property type="entry name" value="PKc_MKK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000090">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000126">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF15">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="147"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="450" mass="50105" checksum="E667BD6841AEF3FD" modified="2016-11-30" version="1">MSDISSSSDTSTASQINTNGSSSLAANKTTPNKNNLRLNFEPDFPSIADGDGVMEVETPEVEEQPVKAVTVSETKIPPSASSSMLSGSRSASATSTMRPNLILTDGARLPTSTSQIDKFRVDSGLQGSSGKLKISPELTFDFTAEDLEDLGEIGRGAYGTVQKMLHCKSQSLIAVKRIRCTVDEREQKKLMMDLEVVMKSHSCPFIVLFFGAIFKEGDCWICMELMDASLDKFYKYVYRKMNQTMPENIIGKIALATVQALSYLKDQLKIIHRDVKPSNILLDREGNIKLCDFGISGQLVDSIAQSRDAGCRPYMAPERIDPNTSKGYDIRSDVWSLGITLYEISTGKFPYPKWNSIFEQLCQVVQGDPPQLGRTKSGCTFSNEFIAFVNTCLIKDHLQRPKYTRLLQHPFLIRSANEVVDVKGYFSYVFDSMGPCLQQRLEDLTLLDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEY9</accession>
    <name>A0A1D2MEY9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001501">
        <property type="protein sequence ID" value="ODM91565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEY9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="556" mass="61597" checksum="79C5E6F808F36861" modified="2016-11-30" version="1">MSLEAIPLPPPQPSFPEILPDGDPSTAPLDNDPHQKLMEELKSFSAGTKKLRPVGVVNPRSRGHSETAKAPPPSTKIKHEPKKNPITKAAKPSRKKVVKQEESEDESSSEEVEEDESESGDGIQIQDLSKLISGLQQQLNLMAKKSKAKSKQKKKKRKSKIDSTTSSTPEPEPESIKESSIQAIETEEPIIPIYQATPQLKPVEHPIETSAVEEPCIFEVQVSPKTPTVEAKDSPVILTPNKDEILQRRASLRPKSSSSFNYKTMPSPLRRKQEEESSPKYESFVEDFKNFSFKRKVVTNAHRQTSESLSSQPVVNEGILNKAEINNPACKKVFNGKQSSAANSVEKKKVEAIPIQKPEIPLKKETKKEKSIKPKLKVKPAAVEKIKTEIPMQNNENETEEEPTSKLTLDWLIASISPDELLKLQQKLKGKIKSNQSFQAPNEDKATPPPPPPTISTSGQAFPKVDDSRSLLFQQITSFSKAKLKKAGCQTEQQSNPRLSSSSPKSPQEQNPSATLKDALLRRFAALNSDEEEESEEGEASSDSEDSDADEDWSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF66</accession>
    <name>A0A1D2MF66_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_15027</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001458">
        <property type="protein sequence ID" value="ODM91655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF66"/>
    <dbReference type="STRING" id="48709.A0A1D2MF66"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="194"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="243" mass="27843" checksum="E8B1F89F3A943782" modified="2016-11-30" version="1">MQNIKAKYDMRYSTNLPLELSYHIAAYIKDVHKRQLAPDFTITLMNNSLNNMVQCLGGLERISTTSTPLSYAIHLFQLTYIFILALPFQLIGPLNWYAIPTVALAAFSLLGIYVIGLENENAFWQEDILPFKYFCNELHEEILSITSHPMPTPKSWLLSTENQPFATTYLNQGRRTPASQLIKRKEDELRKMLKEAGRQVPLRKHLYKERKEEEKKKNKSDRKSGTVPSAGAGPEGENEELVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF78</accession>
    <name>A0A1D2MF78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lysosome membrane protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001465">
        <property type="protein sequence ID" value="ODM91647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF78"/>
    <dbReference type="STRING" id="48709.A0A1D2MF78"/>
    <dbReference type="OrthoDB" id="195015at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF51">
        <property type="entry name" value="LYSOSOME MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="13542" checksum="C6070D48FB32E187" modified="2016-11-30" version="1" fragment="single">SYAGGALKEKQEDEWRPERLGNVLESTLVRYYIFSLTNPEEFRNGSIPEMEELGPFTYREKRIKKNMLRLDDNTLQYDIDWSMHFLPELTKKGLSENTEFTALNAPLIYECNKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFE7</accession>
    <name>A0A1D2MFE7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ras-related protein Rab-39B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001449">
        <property type="protein sequence ID" value="ODM91698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFE7"/>
    <dbReference type="STRING" id="48709.A0A1D2MFE7"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="25499" checksum="D83F304ECF4FA3A7" modified="2016-11-30" version="1">MILIGDSTVGKSSLLRFFTDGKFSEISDQPSGVDFYARLIQVGMGRGSNSSSGILQAGKISVACTFKNFSSITKSYYRNSVGAIVAYDITSRESFERIPNWISEAKRLIEPFSPTFLIVACKSDLESQRVVPVEEGFSYANAMGIHFVETSARSGNNVEEAFQQIAQEIYNRIQSGEYKIDDEGFDGIKQAYSRNGNILCCLKALQKNQSAADGHGFIRAAIVFNVRFCDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFH6</accession>
    <name>A0A1D2MFH6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger protein-likeB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_14940</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001434">
        <property type="protein sequence ID" value="ODM91745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFH6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFH6"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24390:SF159">
        <property type="entry name" value="GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTIONAL REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24390">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM91745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="483" mass="56151" checksum="0E7C4FE7EB8D2ACE" modified="2016-11-30" version="1" fragment="single">DLRMYTMDSNTILRSFSKDRLASLNSGHQRQPTSNQNVCDNQNSETEHNKLHKCTICSNSYLFPGHLENHMKKHTESHPFRCICCGQSFEKRIQLIKHEQVKHSQNGQYPCTSCGKLLHSKGALKIHQQRLHTVVKAFACSLCPSSFSQIGFLSNHIRTSLDPSYSLVVKCSFCELVCRDNYQLQEHMRKHTNEKPFPCSICKRAFATTCYLRKHLEIHQERREKTFCCLMRFARREYLPQHLNLHNSGKGSCCPKCSKLYTSFWFLQLHYLEVHVGSNDNLCICLFCGKKVHGQKTLEHHTAGHTGEQWYFCSKCPSIYRFPEALQKHEFRSHGISLGKKYETAQKFPKEKTFECVFCHKLFTTRGMLKTHILSHIRERPFQCKVCSRSFISKTVLKVHKVVHMDEKKYPCSECSSRFVSKGRLTRHVQVVHERSKDNKKAYARDQHVASHSKKALLSCSVCAKKFRSKIGLKQHLNRHEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFL4</accession>
    <name>A0A1D2MFL4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001453">
        <property type="protein sequence ID" value="ODM91674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFL4"/>
    <dbReference type="OrthoDB" id="10021598at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="29506" checksum="659C803CA0046085" modified="2016-11-30" version="1">MFRLRLAACAAANRRKAQGPQQQKKSRKRKKSEKDARIITGCVGRAVRLGERRMMDARPILRLGCSSRCRHAVHLKDSILSTPHNKSDDWISEDIYKHFTETDSRPITPEHYSRRAVTLPRPSSVVLEKTRKCVTPEPDTKQCQFHNRRVLILDLRRVKSVDAITRQNSLTTGESVDNSTYGDYDYDNRSSSVNRDSASIFHHSTPRNFSISRSTSPKGAIKPKSRIKKPKDRSGSPIAYERSTSPKILEGVSKSPCFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFT8</accession>
    <name>A0A1D2MFT8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_14939</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001434">
        <property type="protein sequence ID" value="ODM91744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFT8"/>
    <dbReference type="STRING" id="48709.A0A1D2MFT8"/>
    <dbReference type="OMA" id="ARKHICQ"/>
    <dbReference type="OrthoDB" id="8300205at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000508">
        <property type="entry name" value="Myeloid zinc finger 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="244"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="378"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="438"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="468"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="531"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM91744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="576" mass="66353" checksum="087DC3FB744FD581" modified="2016-11-30" version="1">MDSRTRSCFVSLVPISSVELLQFQQPINHGVSDKEEDKQTYQCSHCPKSFKYACQLENHAVFHSNLRPFSCRTCGKLFKTKGCVQSHKTVHSKRKYSCSTCGRLLRSLGALNYHVKQLHNGPSKTFSCYQCSTSYTRLSDLSKHIRTLHDPTYKFSVKCTVCDKGFIGNHQLQVHMRSHTNEKPHSCCICGKLFPQRSALQSHLQRVHAEVKVKPFSCIICEKSFFILGDLLPHVHCHTREKPYSCRICSREFGSKSNARKHICQYSTKKPFPCADCSLAYNTNFQLIKHRHTAHGKILHHNELGNNTNERLPKRKQMEKRHNCAICHKLFLSVSHLKVHMFIHTGERPFKCKICGKSHRSKGNLKAHTKIHKDQKSYTCSECSSSFVGMRGLFRHIKAVHERATKSKDIKCKVCNKLFYLKSGLSNHMKVHSDEKPVQCVICEMKFRSSSNLRSHIRFIHISNEKPYFCTECPLSFSDSQLLKRHARKVHSSHFNSTAELRFKCIVCKKGFSQNHALLVHIRVHTDENPYSCATCGKRFRTNSKMTNHSKTHRGQKRTKGKLVKKFERVQPPVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGD2</accession>
    <name>A0A1D2MGD2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Metalloendopeptidase</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_14762</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01001378">
        <property type="protein sequence ID" value="ODM91924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGD2"/>
    <dbReference type="STRING" id="48709.A0A1D2MGD2"/>
    <dbReference type="OMA" id="VWKIMVS"/>
    <dbReference type="OrthoDB" id="431034at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000013">
        <property type="entry name" value="Membrane frizzled-related protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000005">
        <property type="entry name" value="Procollagen C-endopeptidase enhancer 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000240">
        <property type="entry name" value="Vitamin K-dependent protein S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251:SF50">
        <property type="entry name" value="ATTRACTIN-LIKE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811328" description="Metalloendopeptidase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="14">
        <location>
            <begin position="109"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="14">
        <location>
            <begin position="208"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="13">
        <location>
            <begin position="259"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="13">
        <location>
            <begin position="408"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="13">
        <location>
            <begin position="554"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="13">
        <location>
            <begin position="706"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="13">
        <location>
            <begin position="821"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="983"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1063"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1078"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1088"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM91924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1098" mass="122723" checksum="4789066DE8959825" modified="2016-11-30" version="1" fragment="single">QFSLCSVIVVSLVVIVTATGEEYSATSGWNGSSPGLSSRLGKYYKQRWTKEALVQGEFNRTSKAKSGEVEDGEESLGEGEDGFSSEFLFEEDIFMSSFNGDGSGRSRRAATARRERIWDFGVIPYEIDGNFSGAHKTLFKQAMRHWENSTCVKFVERTEEHPNYIVFTEKACGCCSFVGKRGNGPQRILTEEVKILGESYDFDSIMHYARNTFSRSTFLDTILPREDPRDRHRPEIGQRIRLSLGDIAQANRLYKCPKCGRTLLEPSGWFASPYHPTTYSNQSSTSGGNNAQVVDRSVGLNIPQIPPPPLIPGFGEKCEWRIVATHGETIVLNITDFDLPFSDGCKHDYLEIRDGYWHKSPLLGRFCGPNLRFDRPIVSTGSRMVLTYSTTKSVESYRGFHAYYEAVCGGELFGENGHLESPNFPDEYLASKECIWKITVPEGYQVSLQFHSFEIENHENCVYDFLEIRDGISQNSTLMGTYCGYYPPAPLTSTMMGVSKKRVFQRVIKRNLMSARGDLMIVNIPAKIRLGHTHVAVNSDLNSIQMGEKCEDACGGIIEEENGTLTSPSFPNLYPSNKHCAWEIIAPPQTRITINFTHFDLEGNNQECDYDSVEVYSKLSQDELKRHGSFCGPDRQGNSIRIVFTSDNSVQKTGFALVYFTDKDECATDNGGCAQICRNTVGSYMCLCYNGFTLHSNGHDCKEGGCKFDLSTPSHTNELASPNYPEPYPGKKECIWIISTIQGHRVKLVFDELEVEQHPECTYDAVYIYDGSNSDMTLLGKFCGSKIPPPVTSSSNQMMILFKSDGSVHRRGFHAKHYSVCGGVLFALTQEEYIYSHANYGDTMYGDSEDCEWIIEMAADDEAGADTDDLLIDHEEWQQRQQALGPQDYVVELTFLSFEVEDENDCAFDFVEIFNGDDASTQSKSLGRYCGNRLPPPIRSDENGALVIRFKSDDTVNAKGFAAVYRAVSTMEMNNKMKPAIKIPPPVPINPQTPTNTSTSVILPPTNGNTNTNINHMINNDSQETPPTVAKKTIVQRHIVEPSPSPLPPPLPPIIESAFNITTSEEESSVSSSSSSEMTNHLPNTQRYSRRLRKNLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH00</accession>
    <name>A0A1D2MH00_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001320">
        <property type="protein sequence ID" value="ODM92144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH00"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904005" evidence="1">
        <location>
            <begin position="24"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="88" mass="9244" checksum="260B0CF9931E07EA" modified="2016-11-30" version="1">MSRTLVGIIVICIAIGMLEICEASPGQGGNNVGQGLDDLNLLCLSSPPHLATYADVTVNGRGYYVLHCCATAMVALNWETCRVGFLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHM4</accession>
    <name>A0A1D2MHM4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH psq-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001264">
        <property type="protein sequence ID" value="ODM92334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHM4"/>
    <dbReference type="OrthoDB" id="7421119at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05225">
        <property type="entry name" value="HTH_psq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH psq-type" evidence="2">
        <location>
            <begin position="88"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="17168" checksum="1E92837B79FC6400" modified="2016-11-30" version="1">MFRRIVYKGRVRSSSSLVLTRLSSMRAACRSSESISCSETGTESGNEQGDSKSGDKKDLGKMLTLPPGIRPKKIRVIRKHKVEVLTDAALCILEGMTFQQVSEKFDVPKTTLRDFMVRRGLLQRGLSKKGGAEGGIAAATVSVPPLKSSHTDWEKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHX5</accession>
    <name>A0A1D2MHX5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calpain-15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001199">
        <property type="protein sequence ID" value="ODM92563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHX5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001315">
        <property type="entry name" value="CARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00619">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="5">
        <location>
            <begin position="188"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="265" mass="29958" checksum="97C58BF31EEBDA6F" modified="2016-11-30" version="1">MTDQEATTPSSSLNTIMTNYAEIVAAFQIIRTLRIEDLKLHPDVFSIPFYRDTMLYREPEQDEFIGANEVLRKNVYYIATLTENVSDALVDQLLAGEILNEEECNAIRKQPTNKLRSVQLFAFLVGKEDPDNNILARILTTLKEIGNENVVEILQPFFDIENLDNNDAVVDDERHHPDGAHGGIADTEEGLKWTCRFCTFRNNAEMNFCEVCARTDNSDPGDSIDFVLCPKCTLVNEPGCDACILCDFRFNQVPQTDSSDDEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIB8</accession>
    <name>A0A1D2MIB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HEAT repeat-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001195">
        <property type="protein sequence ID" value="ODM92584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIB8"/>
    <dbReference type="OrthoDB" id="66533at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052107">
        <property type="entry name" value="HEAT6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13366:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13366">
        <property type="entry name" value="MALARIA ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="566" mass="65258" checksum="5E97F6172DF1132C" modified="2016-11-30" version="1" fragment="single">LIDNLIMAQREGDKWHAKDILVSPRPGPKALFRNSTQTDWTRINEVPPLPEDIDDEKMTEKAISKKLSRNYYEKLWQCWNDLYVVFDLGCRLNLGRAKRAIKLTTNCFPTYLELMERRLTYAHYMKCPTDCMVEAIKCCVLVTTKMSKYVDPEYLEHGLDPEFLRKFDVHFQTLVATLIDNILNCSSALGSVMIDVLAAIGPFMWLRLPADVQKRIIPFLMSVTNADSKHVSSQVKSRVGRCFGKYIEFPWFRTNFPFLVEVFELCERFLLQSENAMKISYAWVFANWTDVVVSDYSSTDENFFDNDINLRILSTLLLYVDVPLKAKYNIGRACGNIFSWMHLQLLEIEVVRTAVRKLTDYLVSMIGTGQDYKLRWNCAYAVGNVLGNPIFFHYLEENVIAPIIKALSKWMVNSQNFKERAQCVASLRKVVDKDIYGERYALVWNHLCLSLSRLPIETCEGIQKFKSECILLFFHLINMLELKDFPRINDAVTGNMQHLRSLVDDFAGGIPMEQFDAVITANDYIKDVEQQLEMLPYEITASALADIVRLALHLHRGARRGSISST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJZ8</accession>
    <name>A0A1D2MJZ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chromobox protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001030">
        <property type="protein sequence ID" value="ODM93288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJZ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MJZ8"/>
    <dbReference type="OMA" id="SIANTTW"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00034">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017984">
        <property type="entry name" value="Chromo_dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00504">
        <property type="entry name" value="CHROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="9"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="104"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="18103" checksum="D81DB16D1C01A500" modified="2016-11-30" version="1">MESSSDDFYIVEKVLKKRKGAMGKTEYLLKWTGYPHSDNSWEPQENVNLALILEFERKMKKKGTEAEMRQEPPNTGANEGSSSSEEKEVDGQEESNASGVDVAPEPENILGVAIDKGKLWFLIKFQGKDEKKLVCSKRANIKWPQKVIEFYEERILFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKK6</accession>
    <name>A0A1D2MKK6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynamin-related protein DNM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13309</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001007">
        <property type="protein sequence ID" value="ODM93374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKK6"/>
    <dbReference type="STRING" id="48709.A0A1D2MKK6"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GED" evidence="3">
        <location>
            <begin position="437"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="529" mass="59629" checksum="E03824D3A8C1CC79" modified="2016-11-30" version="1">MRNDTWCEFFHKPNEKFDDFRKVEQEIISRTDEIAGTDFGITIGQQPDDIEEQVKNLILGYISADDAVILAVCPGNIDIANNESIKIAKTVDPTQERTIVVLTKLDLTDDYSKMTDVLNGKVVPMKLGYVGVINRSQDDLKGDKPIEEVLKHEKAFLAEKFSSISAKHGISCLAKKLNRILLQRILACCSGLSVNIRNLSTASESELRELGVDEEMTVEEKKKELFKIVDEFAKEYKAQIDGMSRSEVQSLNLTCGARIDIIINNNLPNELDALKSFENMTDTEMLVAIRNSMPVGARFINPEVALNHFIKEEIKKMAPVAIHTAQLLHQEMVNMIESCLENKRFPKANTAIYSIVSELLSSKMEQTVYHLEMYFEIQSASAFSANEGYAKFFKKVLGPIPQIDLGELPMPLVPNVGGKQGLEKSPAGFTTEQSSMFQQLKDLANQVYQMARWQAQDYIVKGILHTLIYKSIDTVAVELNTRLNESHIPENLIREPDEIHNRRTQLKSNLVEYNNALKLLDELRKASAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLT3</accession>
    <name>A0A1D2MLT3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Latrophilin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_12658</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000870">
        <property type="protein sequence ID" value="ODM94029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLT3"/>
    <dbReference type="STRING" id="48709.A0A1D2MLT3"/>
    <dbReference type="OMA" id="LYRMVVH"/>
    <dbReference type="OrthoDB" id="1100386at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000058">
        <property type="entry name" value="Adhesion G protein-coupled receptor F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057244">
        <property type="entry name" value="GAIN_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046338">
        <property type="entry name" value="GAIN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000203">
        <property type="entry name" value="GPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011:SF347">
        <property type="entry name" value="FI21270P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01825">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00303">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50221">
        <property type="entry name" value="GAIN_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="850"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="883"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="914"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="954"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="995"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1046"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1075"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="15">
        <location>
            <begin position="43"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GAIN-B" evidence="13">
        <location>
            <begin position="644"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="14">
        <location>
            <begin position="848"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="333"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1130"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1227"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="372"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="411"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM94029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1250" mass="138815" checksum="7BD86EB8786CD234" modified="2016-11-30" version="1">MSDQVQGAHHQKQINYFYKTDAVHEDEAVTNGISFISNFVSFSLTPIGCFSTWGVHNTSMHDPIRSPIYNESYTPTSCAEACKNEGPQYQVAILKGAECKCSFTYDFNLWKAPDEDCYIPCPMEDYNATAPRTQVRNACGGNRAYSVYCRSGEDSCTDIPYRVPEAQEEIIAKVSEMDKVRSWNSQRDKLEHECASCDYGNGQDCKKGYIFPDFDYFPVNNPTDCIDYCSQNVSYTVVTTTSGEQIREPSKHAVLTWWEFERNRKDLSICHCINDKIRELYVAVSNVSECEKKCPGDPSSTCGGLQRDHKMYGSIYCLGSLLDGTCQVAEVTSTVQPQSTTTTEDPCSEGALGCDDPDPTDSNESTEDPTTTEEPTTTEPPSTTETTLKDTSGTPPETTTTSTTCDDDDVSTTTPVPQTSSTTLTTPITTPSSTSATTPQRTTTTLSPTPVSSFCKQKCRSIDRHGIKWEVCAGTVGIGPCFQNSTGVVFWSCSKNGTFVTPQPDSSNCSSPWLEEKHEELEKVDDIDEARNYIDRLSEACKSAQKPGSSTTYFGHELRNITSLVGRILEKAKGFSPTLSNYERVVETAIDLSAFLMQYQDPWKDLSDLEKSSVSTSLIDNTEDSLFHLTELVKTETYTKIYTQNLTDMSKFLILAESFHKQKAKVQSGTYEFPPSSVRELQDSFIKLPANWQDLIPSNKVDIAAMSIDSHLGAGSKIEVSNQKVINSRLISFTVISSGTLSGNMKAMQNASINFKDKGVEITFRHDTEAWGDEVQNVPRKLHEGEKPKAVLGSTQCVYWNTKTETWSSNGCQIIVSNRYETVCECNHLTSFAVLMDIHRYVGKEFALELLTIILCSLSTVALLLSVIILSSVNGLQKIRATITKNLSACLMLGNAMVMFVLDRNYFHMSEGVCMGAAIITHYIFLCAFMWMVIEGVQLYRMVVHVFDSGRSYIKHFGIFAYGTPLIVVAITATTGYLKGDQPYGGDVYCWLDGMYIWSFLAPVAIVITINLIILFIALKTAYQLQQNKKLSPTFLMGRVRSYKTWFKGSFSLTVILGLTWVVGFFTLMNSPGGIIAAYVFTLLNASQGIFIFIFHCVFNDKVRAVTRRNLSTYLPSWISSSISTNPGGNENSIYGKRPLSSMKSGESVLSDKPKPKLRRSSGLPEQKQPYIISKRKSQSDFTLNKTELEKDYKVNLTDAHNHYVSVNPVQRCESVGTISSMDSIPFSDNGNISSDTSQSALISNEKVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP11</accession>
    <name>A0A1D2MP11_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000746">
        <property type="protein sequence ID" value="ODM94809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP11"/>
    <dbReference type="STRING" id="48709.A0A1D2MP11"/>
    <dbReference type="OMA" id="WPAGRIP"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="4">
        <location>
            <begin position="59"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="42168" checksum="53792F912803C735" modified="2016-11-30" version="1">MFSKPILPHQIRSFRKLDSLSTRNTTRVRYNDGTSKAKEFYQIDDMLFLNPNKSKQHRAGQYRESYRWATARIPYTFGPGYSEDEMRQIFFTMKYIEQYTCVRFAFRTERDDNYLYIRNVEGKCQSFVGNVRPSSFRPESRSCAVPNFPGHVLHELIHALGFFHEHARDDRDNYIEIVYDNLSEDDDILRNFYKNSDSDITTAFHTTTEVLCTTQKAGSINGDATIIRRAPLPQGIPKPLDGEMGQRERLTEGDAQMIRNMYKDICPMIFSGTSEDTPTMFLVKNFRLVLVLLGLIAVIGLSFADEPEEGAGGDGKNDTNPGPTQPTPKPGGTSPTKSTTGGQTMVGPSALLLLLAAAGPVIQYHYRKLSPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP94</accession>
    <name>A0A1D2MP94_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase/reductase SDR family member 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000739">
        <property type="protein sequence ID" value="ODM94857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP94"/>
    <dbReference type="STRING" id="48709.A0A1D2MP94"/>
    <dbReference type="OMA" id="TMYLAQY"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053011">
        <property type="entry name" value="SDR_family_member_7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44269">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44269:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="332" mass="37093" checksum="46A6D6F12B263639" modified="2016-11-30" version="1">MDFCLAFGSIAVFGFLAWILAILSIDADLLTIIYTYFGKSLDGTFADKVVWVTGASSGIGEAVSKELAKHRTKIVISARRVDELNRVKRECLELSNSLTDADILVLPLDMTDYSSHQSAFKKVLDHFGRLDILVSNAGRSQRANWEEIETEVDKQLFDLNVFSLLALSRIVLKYFYRVGKGHLVVMSSVAGKNGIPFSASYTASKYALHGYFACLRNEIASKNIAIPVTLICPGPVFSGFLKEAFTAKKDQKFGQDVPSTHKRMSAQRCSYLTLTAIANELEECWVSIFPYLQLTYLSHYQPYLAGCVWKWLSSSGKAMKMRDGRESIQKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ70</accession>
    <name>A0A1D2MQ70_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Homeobox protein goosecoid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11499</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000701">
        <property type="protein sequence ID" value="ODM95183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ70"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ70"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050649">
        <property type="entry name" value="Paired_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329">
        <property type="entry name" value="HOMEOBOX PROTEIN ARISTALESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329:SF516">
        <property type="entry name" value="HOMEOBOX PROTEIN GOOSECOID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="5"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="2">
        <location>
            <begin position="7"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="13489" checksum="30B52C0E54CB23C6" modified="2016-11-30" version="1">MGVPACLNQKSTIFTEEQLEQLEATFEKTHYPDVVLREQLALKTDLKEERVELPFDISLRVHNSRIYKLSVGKTNIKKRDGYGFSPRIRFRLTAAPDFIHVIFSRGTRERERIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQY9</accession>
    <name>A0A1D2MQY9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.179</ecNumber>
            <ecNumber evidence="3">1.3.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-xylose 1-dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Dimeric dihydrodiol dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_11448</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16729"/>
            <dbReference type="ChEBI" id="CHEBI:10702"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18135"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="4"/>
    <dbReference type="EC" id="1.3.1.20" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000695">
        <property type="protein sequence ID" value="ODM95224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQY9"/>
    <dbReference type="STRING" id="48709.A0A1D2MQY9"/>
    <dbReference type="OMA" id="WHFEADE"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047115">
        <property type="term" value="F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="12">
        <location>
            <begin position="138"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM95224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="38340" checksum="2D30A6B80CE8B366" modified="2016-11-30" version="1">MSDLTTRPLRWGIISAGLISHDFVVALGTLNPQEHIAVAVGARRLEDAEKFAKLHGIPKAYDSYQKVFEDPEVDVVYIGAIHPTHLPLGKAALDAGKPVLCEKPLCINVRETKELLEHAKAKNLFFMEALWVRFFPAYQKLKELLSTKAIGDVANVFISFGVPLGDVDRCKLLNLGGGTTLDIGLYCTQLSILVYGQEFPEKILSTGVLNESGADVVGSTTLKFPSGGLATFITSYKSTMPNEAFYHWNQRKHQDAFSILERNKLELLTDGAPPQVFEYPVPVGAKPINFWNTTGLSYQCHEVRKCLIQGKVQSDVMPHSETLRLSQILEEIRKQIGVKYPQDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS86</accession>
    <name>A0A1D2MS86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ski oncogene</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000638">
        <property type="protein sequence ID" value="ODM95664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS86"/>
    <dbReference type="STRING" id="48709.A0A1D2MS86"/>
    <dbReference type="OrthoDB" id="3938623at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046332">
        <property type="term" value="F:SMAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030514">
        <property type="term" value="P:negative regulation of BMP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.20">
        <property type="entry name" value="Ski"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003380">
        <property type="entry name" value="SKI/SNO/DAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037000">
        <property type="entry name" value="Ski_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023216">
        <property type="entry name" value="Tscrpt_reg_SKI_SnoN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10005">
        <property type="entry name" value="SKI ONCOGENE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10005:SF25">
        <property type="entry name" value="SNO ONCOGENE, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02437">
        <property type="entry name" value="Ski_Sno_DHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKI/SNO/DAC" evidence="2">
        <location>
            <begin position="294"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="350" mass="37444" checksum="2412EA5358B6A194" modified="2016-11-30" version="1">MKIPQSTPTSSSATFEISMMEGKPSPHLKKVLKSYQLTAANTLNGPNSVLSRFDNSPSNTSSSGSSSAVDIISNSLAASHGSLIGGPPHYGLKIEKCVKALTSGELHNNHHLNHGPLKLSTVLKSRMENGSLAGPPGPSSPDSQERDRDKSNIRMGIINGAEVEVKKEPEDEKSQIDDDGSELLESAHVNPVATINVNAVSSLSSSSSTTGNYPTRKDRLREHTPEEMMAATALAFAKELPPEGLHVTRVVIHIGPLASATSPIGELVLQDQSVSQYQFMPTTTTPSSCGNTSTAPPILSTPDRSRTEKLETLLEGEYISCFVVGGEKRLCFPQILTSVLRPFTLHQINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT38</accession>
    <name>A0A1D2MT38_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000568">
        <property type="protein sequence ID" value="ODM96176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT38"/>
    <dbReference type="OMA" id="MIRGINT"/>
    <dbReference type="OrthoDB" id="9973045at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="43286" checksum="956647507D422FF1" modified="2016-11-30" version="1">MSIKSVKGLRLYYPTDKGPIDTYQLGHDGRVEYLAAEIGVDHLDKGNDTNDEWVKWAKTRGTSTDEPGLILSSRLGGSGTDKTNLFPKSPLLDKTLWKEHEQAAVEEASDMRKWKKIKFAIKLEYPSDDSTRPSALEYQYDLPSGTVLYGKVKNEAAAGEVEPEEEEYEEEEEEEYEEEEIEEEEPAPAEEAPKVEAVTPTPVQAEVSKVEPPPLTVEPASPSPPPEPVIVEKPKPTPTEPTYQYRSPIHEPPKAASPARDEHPRNEPSPKKAKPSKEKIDVQERSIITKSDLIELIPVIGSCKLALETAQAAYNGDGKLALRKAVQCSISLVADFYFGRAIARHGQILAKQVTEQTIVRFVSKAENQIIIVSTFKAGNQLLNTLSRMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVT4</accession>
    <name>A0A1D2MVT4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000477">
        <property type="protein sequence ID" value="ODM97028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVT4"/>
    <dbReference type="OrthoDB" id="8295363at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM97028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18703" checksum="29D954EC6C62F72B" modified="2016-11-30" version="1">MFLEPRHQTQFDNMRASQESLSPVRIKTKDALPAKTNVTLHIFNNPGIRKGYSVSYGFFRNKECLHGQDHYCITSPEFGRVRAVVLNAERFAENENLNYIKDHFLLEPPQAFVTILNEGSSNERKFYEAVFLGGYPTRKDASRVIPLDRWENISVGNLHVLCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXC1</accession>
    <name>A0A1D2MXC1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaJ homolog subfamily B member 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Endoplasmic reticulum DNA J domain-containing protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins. In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1. Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Required for survival of B-cell progenitors and normal antibody production.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with HSPA5/BiP; interaction is direct. Interacts with ERN1/IRE1 (via the luminal region). Interacts with DERL1.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000427">
        <property type="protein sequence ID" value="ODM97618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXC1"/>
    <dbReference type="STRING" id="48709.A0A1D2MXC1"/>
    <dbReference type="OMA" id="YNFRQHY"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904693" description="DnaJ homolog subfamily B member 9" evidence="6">
        <location>
            <begin position="26"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00041533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00045428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="21569" checksum="200DE5AC1713D2A2" modified="2016-11-30" version="1">MKPDIRRRFLIFSVIILLTTDAVCGRSSIKKDFYEILGVQKSATDREIKKKFRQLAVKYHPDKNQSPGAEEKFKEMAEAYEVLSDKARRREYDRFGLEGFGQERKAEKRHGQGFDFGDFFPSFDFDNYLDRGYYAFQSYFGGNDQHHGGSERGGYQRSHSGGEKRCWTVKKRVGNMISTYTQCSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXI5</accession>
    <name>A0A1D2MXI5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Collagen alpha-1(XV) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000425">
        <property type="protein sequence ID" value="ODM97651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXI5"/>
    <dbReference type="STRING" id="48709.A0A1D2MXI5"/>
    <dbReference type="OMA" id="LYFRCTR"/>
    <dbReference type="OrthoDB" id="10060752at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048287">
        <property type="entry name" value="TSPN-like_N"/>
    </dbReference>
    <dbReference type="SMART" id="SM00210">
        <property type="entry name" value="TSPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0176">Collagen</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904712" evidence="2">
        <location>
            <begin position="23"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Thrombospondin-like N-terminal" evidence="3">
        <location>
            <begin position="6"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="20592" checksum="946E63933A2C13C6" modified="2016-11-30" version="1" fragment="single">MIFFKLFAVRLLLTLEPSIFEAGLDGFPAYGLREGADVKSPYRLFLPESLYRDFALLATIKPERREPSYIFAVVNPHDTIVQFGLKISPSLTSSHHMISLMYTDVGSHIMTQNLVSFEVPLRTRKWNRFALKVIGDNVTLFLNCREHSSKNVMRNPKELTLDPASTLYIGQAGPIVKENFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYW8</accession>
    <name>A0A1D2MYW8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08675</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000390">
        <property type="protein sequence ID" value="ODM98004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYW8"/>
    <dbReference type="STRING" id="48709.A0A1D2MYW8"/>
    <dbReference type="OMA" id="LWRLEFD"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000163">
        <property type="entry name" value="SRSF protein kinase 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000275">
        <property type="entry name" value="SRSF protein kinase 2 isoform X3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="58"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="228"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="566" mass="63985" checksum="C7121ED2A2BC7B35" modified="2016-11-30" version="1">MVLNWDRSDPRTSSNTSEGSDDDEEILGSDDDEQEDPRDYCKGGYHPVKIGDLFHNRYHVVRKLGWGHFSTVWLCWDLVGRRYVALKVVKSAPHYTDTALDEIKLLKCVRDADPTDPNREKTVQLLDDFKITGVNGTHVCMVFEVLGNNLLKLIIRSNYHGIPLQNVKSIMRQTLEALEYLHAKCKIIHTDIKPENMLLCVDDQHVRQLANEATNWQKLGVKLPGSAVSTAPKEFQGGANSKMSKNKKKKMKKKAKKQAQLLEQQLQQLQEVEEHETPGPDGDCEENSTTNQDSMDSFAGKGPQRDVKTEENEIDSEDSETGAAEHSDSNENKSGNMTIPKKHSNVENRKSFSELAEANVISGAHMNGHESQMHQSKSTGERELVDMVDDGHASTSSTMRRTTSCPDQKVAGRPDPVKEICDIFIKIADLGNACWVDHHFTEDIQTRQYRCLEVLLGAGYGPPADIWSTACMAFELATGDYLFEPHTGEDYSRDEDHIAHIIELLGELRHITKLKPWGLFDVLYEKYEWAEDDAKEFADFLTPMLQFDPTRRATAGECLKHKWLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ57</accession>
    <name>A0A1D2MZ57_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein eS17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000364">
        <property type="protein sequence ID" value="ODM98319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ57"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ57"/>
    <dbReference type="OMA" id="FTTHLMA"/>
    <dbReference type="OrthoDB" id="1727351at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.60.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="entry name" value="Ribosomal protein S17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_eS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018273">
        <property type="entry name" value="Ribosomal_eS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="Ribosomal_eS17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="137" mass="15859" checksum="21987626165C0483" modified="2016-11-30" version="1">MGRVRTKTVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKPLRNKIAGFVTHLMRRLQNSQVRGISIKLQEEERERRDNYVPEESALERDIIEIDQQTKDMLKMMEFPNLSGLQLTQVTPGQQYGGGGGGNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ64</accession>
    <name>A0A1D2MZ64_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000394">
        <property type="protein sequence ID" value="ODM97945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ64"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM97945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="17135" checksum="6E120ECB8E265A77" modified="2016-11-30" version="1">MFFWEIQSIESVMADGVQRAIVCDFEVGEATYTTARTKWRLHLDVVNDEPALVVQKLSPTNKPVFYRLSIQVMKSPEEETDIIGYPNTKLFYEASDSNQTTINKDDIKFELHRQLAYGCNYTTWFQDAVVNDSLLLRIDFETCESTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ77</accession>
    <name>A0A1D2MZ77_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endocuticle structural glycoprotein SgAbd-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_08436</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000371">
        <property type="protein sequence ID" value="ODM98241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ77"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ77"/>
    <dbReference type="OrthoDB" id="6368834at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904771" evidence="3">
        <location>
            <begin position="17"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="24752" checksum="E4A03E19200D4BA7" modified="2016-11-30" version="1">MRPFVVFALLVAGVSSSVIRVDSGYGGALRSDSYGATLVREIPITSLSHDIRGSLSDSLSYTTGNGISVVDNTQAVQGRGGEYVDEYGQLVRSDAMISKAGSYSFTTPEGQQISTNWVADENGFRAEGAHLPRPVEMPAEHAEAHRLALSRVSGVSSYDSPALIRTSNYDAPALIRTSNYDSPALIRTSNYDAPALIRTSNYDAPAIRVQSYDAPAVRVIESSPLLVRSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZF0</accession>
    <name>A0A1D2MZF0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000361">
        <property type="protein sequence ID" value="ODM98368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZF0"/>
    <dbReference type="OMA" id="MHINDPL"/>
    <dbReference type="OrthoDB" id="8295038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="66429" checksum="3EFCE1D2FBF5A949" modified="2016-11-30" version="1">MVVLQEETEDYGGNMPLPIHPLLIDHVVKKILEYAVSSHNVNLLSCRSVCKIWNQMATSLYKSQQQVEVGNYSTSVPRFRRLIKLRKSCPNNFSKKNSKTFAPSWPFPFVRFRLCQEVFQPIYASVITDFFQTFQDTLEVLDIWLDLRSSLVEVPIHSKSKLSSFANLKTLVYDDRRVILHGSEDNRGSLLKTLVEHAPNIRNLSIRFQRDFRGSLECASETVLNRIRNIFSRVEIQRSLKFLKLDMHINDPLLNSLKCCNLRVETLELALRGSSFTFPVFQNFMESLQMNLMKLKICYIERDSSCLLVFPAMTALRELEIEGTDAFAKHSVAFGDLTFQQNFPQLQSLRISIWASVHLRWAQFFQNKQPIWTIKELKLPGELCDKTMMADAARMFPNLKKLQISVYSLTLDSLQTIFEGMPQLEELTVTKFPSLWDRNETNIDHILTGISISDCDKLVEDNVVLENISNDKLMILKTSAGLTDLKKLKKLSMPDLQYQASYTDITGYLAFRRMPNLKYLNVGRSYLGNSCLMQLTQKFPEMEEQRKMLPMYLKEPEDDDDGSYLDLPGDTCVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZL7</accession>
    <name>A0A1D2MZL7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="12">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_08186</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. PP-2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000349">
        <property type="protein sequence ID" value="ODM98493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZL7"/>
    <dbReference type="STRING" id="48709.A0A1D2MZL7"/>
    <dbReference type="OMA" id="PSHGLMC"/>
    <dbReference type="OrthoDB" id="5593063at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030431">
        <property type="term" value="P:sleep"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07416">
        <property type="entry name" value="MPP_PP2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041751">
        <property type="entry name" value="MPP_PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="14">
        <location>
            <begin position="147"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM98493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="560" mass="64096" checksum="E31E19AA781A397B" modified="2016-11-30" version="1" fragment="single">MTSSANNQKLSTTERVIKSVPLPPSHKLTMAEVFDSKTGKPNHERLKQHFINEGRIEDAAALKIINDGAALLRAERTMIDIEAPVTVCGDIHGQFYDLMKLFDVGGDPASTKYLFLGDYVDRGYFSIECVLYLWSLKIAYPNTLYLLRGNHECRHLTEYFTFKQECKIKYSERVYDSCMEAFDCLPLAALMNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNTSEHFTHNTVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMAEGEEGAEDGKKSFFCLLSTLLKNNNLNLTYHHLNFIKFNKFIYTSRMKAQIDTHFPKNNMNAFSRLTECIKEGSKEFLFNLVLDTPCLSSFKQFVYADNTHRSFAANANIIPSTGNDSMYQYATPNLTTHTRLTPVANPSRKSGESNDDNGQMQILTKKISDSLILVTSLLYMYEQYKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1B0</accession>
    <name>A0A1D2N1B0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="23">Glutamate receptor ionotropic, kainate 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_07843</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Postsynaptic cell membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000318">
        <property type="protein sequence ID" value="ODM98834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1B0"/>
    <dbReference type="STRING" id="48709.A0A1D2N1B0"/>
    <dbReference type="OMA" id="CCTAHEP"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022824">
        <property type="term" value="F:transmitter-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06382">
        <property type="entry name" value="PBP1_iGluR_Kainate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000001">
        <property type="entry name" value="Glutamate receptor ionotropic, kainate 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000010">
        <property type="entry name" value="Putative glutamate receptor ionotropic kainate 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001508">
        <property type="entry name" value="Iono_Glu_rcpt_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00177">
        <property type="entry name" value="NMDARECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="9 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0628">Postsynaptic cell membrane</keyword>
    <keyword evidence="10 23" id="KW-0675">Receptor</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0770">Synapse</keyword>
    <keyword evidence="4 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="801"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="21">
        <location>
            <begin position="405"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="22">
        <location>
            <begin position="415"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="856"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="867"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="662"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="site" description="Crucial to convey clamshell closure to channel opening" evidence="17">
        <location>
            <position position="641"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with the cone snail toxin Con-ikot-ikot" evidence="17">
        <location>
            <position position="668"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="728"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODM98834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="909" mass="102990" checksum="C29C2A04D32F457A" modified="2016-11-30" version="1">MSGLFDEADPSEETAFKHAVERVNAEITVLPRSRLSTQIERLSFGDSYHASNKVCQMMREGIAAIFGPQSPEAASHVQSICDAFEIPHIETKWDYKIRKENYLINLYPHPMTLSKAYNDLVEAFNWETYVIIYENNERLYTLQDLIKASAPSTRKAVLKQLPEGDDYRSLLKDILYATDIFNIFIDCSTDKVPEVLKQAQQVGLMTYHYSYIITSLDIHTLDLVDFSYGDINITAYRIVDPDRPEVDAIVKQWNSHISVDNYNSRSHMYGGPYYVYNDILFFLQTETALVYDAVFLFGKALHVLDSSQRIDIKPLNCDSKETWQHGYSIINYMKMVQLQGLTGLIQFNTSGYRTDVQMDVVQLKRDGLRKIGTWDSKFVTKFNWTKQDAEIEAVQDDTIDLKNRTLTVTTIKNDPFLMLKISTEPLTGNEQFEGYTVDLLNELSKELGFKYNIKLVSDGSYGSLNKETGKWNGMIREVIDGEADIAVADLSVNKDRQSALDFTMPFMNLGISILFVEPKFKAPELFSFMNPFAVDVWMYMFYAFFGVSIVLFIIARVSPMEWDCPHPCIEDPDELENQFTLLNSFWFTIGSLMQQGSDIAPKATSTRMMAGIWWFFTLIMVSSYTANLASFLLVQEKDEPIKSLQDLARQDVIKYGCVGTGSTASFFKFSPFPERVVMWKKMEEWNSKSPGILPKDNVAGRDKVLRDEGKYAFFMESTVIEYAVERVCGLYQVGGLLDSKGYGVGMHSPYRQYFNGGILRLQENGILDKLKRKWWKEERKGTGCAAEGGESGVTPLRIANVGGVFVVLVGGCAVAIIFAFVEFFWENRKIATDEGGTVVEEMSKELKFALSCSSNSKPVKKEKKDSLSSQEGNGEPQDSNQYLDLGLDSYGFPNAPPRANGGINQDGYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Z2</accession>
    <name>A0A1D2N1Z2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-xylulose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_07401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000289">
        <property type="protein sequence ID" value="ODM99278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Z2"/>
    <dbReference type="STRING" id="48709.A0A1D2N1Z2"/>
    <dbReference type="OMA" id="MSVHKTV"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="258" mass="27065" checksum="A293C4CD97996ED6" modified="2016-11-30" version="1">MSLETQFGGKTALITGAGKGIGRALAVRLSGYGAKVYALARDQNDLTSLKDECPTVEPICVDLMDWDATRTALSQIEPIDILINNAGFGGMQPFLQVTPDVFDQIIGVNLKAAVNVGQVVAEKLIEAGKGGSIVNITSMAGKRTLANYSVFCSAKAASDMLAKGMAVELGQHKIKVNSISLGCVSTPTFQKFVEACGGQGNIDQILAQVKSRTPMTGSDDHPIIPMDDVVNTILFMSSDLCGMLSGENVVLDGGFCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2E2</accession>
    <name>A0A1D2N2E2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 17">Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase</fullName>
            <shortName evidence="17">GNT-I</shortName>
            <shortName evidence="17">GlcNAc-T I</shortName>
            <ecNumber evidence="14 17">2.4.1.101</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15 17">N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_07443</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 17">Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11456"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="Rhea" id="RHEA-COMP:14368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60625"/>
            <dbReference type="EC" id="2.4.1.101"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="17">The cofactor is mostly bound to the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 17">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Golgi apparatus membrane</location>
            <topology evidence="1 17">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the glycosyltransferase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.101" evidence="14 17"/>
    <dbReference type="EMBL" id="LJIJ01000293">
        <property type="protein sequence ID" value="ODM99224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2E2"/>
    <dbReference type="STRING" id="48709.A0A1D2N2E2"/>
    <dbReference type="OMA" id="KGYDLSW"/>
    <dbReference type="OrthoDB" id="440755at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003827">
        <property type="term" value="F:alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02514">
        <property type="entry name" value="GT13_GLCNAC-TI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000055">
        <property type="entry name" value="Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.20">
        <property type="entry name" value="N-Acetylglucosaminyltransferase I, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004139">
        <property type="entry name" value="Glyco_trans_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052261">
        <property type="entry name" value="Glycosyltransferase_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10468:SF0">
        <property type="entry name" value="ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10468">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03071">
        <property type="entry name" value="GNT-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 17 18" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 17" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 17" id="KW-0464">Manganese</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU368119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM99224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="393" mass="45149" checksum="445F7E718F5CE24A" modified="2016-11-30" version="1" fragment="single">GRKEVKDPNYEGNKDGEEFHQGEVIEGGGAADVAVKNTDDANASPSHGSVIAVLVFVCNRPSIKRNLDQLFKFRPSAEKFPIIVSQDCGSHPATTSIIKSFGDKITHIMQPDLSDIKVPPKEKKLKGYYNIARHYGWALNYTFNTLGHNNVLIVEDDLDIAPDFFEYFAATLPLLYEDPTLWCISAWNDNGKPKRINETAYDLLHRTDFFPGLGWLMTKSLWTELMVKWPKGYWDDWMREPPQRKDRSCIRPEISRTSTFGKDGVSHGTYYQNHLRFIKLNDHFVPFTSLDLSYLKKDKYDVAFVKRVYSSQLVSSVEELKRVTNSTPATDPTEFRLTYRTKVDFRIFAKKLEIMEDFRAGVPRTAYRGVVPFLYNNKKVYLAPGANWNSYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N363</accession>
    <name>A0A1D2N363_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="31">ATP-binding cassette sub-family B member 6</fullName>
            <ecNumber evidence="30">7.6.2.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="32">ABC-type heme transporter ABCB6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="44" type="ORF">Ocin01_07002</name>
    </gene>
    <organism evidence="44 45">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="44 45" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="44">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="40">
            <text>coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66768"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167478"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="40">
            <dbReference type="Rhea" id="RHEA:66769"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="39">
            <text>coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66664"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="39">
            <dbReference type="Rhea" id="RHEA:66665"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="34">
            <text>coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="34">
            <dbReference type="Rhea" id="RHEA:66681"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="33">
            <text>heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19261"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.6.2.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="33">
            <dbReference type="Rhea" id="RHEA:19262"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="37">
            <text>pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61360"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58687"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="37">
            <dbReference type="Rhea" id="RHEA:61361"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="36">
            <text>protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61336"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="36">
            <dbReference type="Rhea" id="RHEA:61337"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="35">
            <text>uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66772"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167480"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="35">
            <dbReference type="Rhea" id="RHEA:66773"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="38">
            <text>uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66776"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167479"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="38">
            <dbReference type="Rhea" id="RHEA:66777"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Early endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endosome membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endosome</location>
            <location evidence="2">Multivesicular body membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Golgi apparatus membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Late endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Lysosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="28">Melanosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Mitochondrion outer membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Secreted</location>
            <location evidence="7">Extracellular exosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="29">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="44">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.5" evidence="30"/>
    <dbReference type="EMBL" id="LJIJ01000263">
        <property type="protein sequence ID" value="ODM99680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N363"/>
    <dbReference type="STRING" id="48709.A0A1D2N363"/>
    <dbReference type="OMA" id="YYGAEHY"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015439">
        <property type="term" value="F:ABC-type heme transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18581">
        <property type="entry name" value="ABC_6TM_ABCB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000287">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032410">
        <property type="entry name" value="ABCB6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16185">
        <property type="entry name" value="MTABC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="20 44" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="26" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="19" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0967">Endosome</keyword>
    <keyword evidence="23" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="27" id="KW-0458">Lysosome</keyword>
    <keyword evidence="25 41" id="KW-0472">Membrane</keyword>
    <keyword evidence="24" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="45" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0964">Secreted</keyword>
    <keyword evidence="21" id="KW-1278">Translocase</keyword>
    <keyword evidence="15 41" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="22 41" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="535"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="41">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="43">
        <location>
            <begin position="293"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="42">
        <location>
            <begin position="636"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00024320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00024385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00024439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00031413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="ARBA" id="ARBA00047649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="ARBA" id="ARBA00047753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="35">
        <source>
            <dbReference type="ARBA" id="ARBA00047789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="36">
        <source>
            <dbReference type="ARBA" id="ARBA00048309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="37">
        <source>
            <dbReference type="ARBA" id="ARBA00048455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="38">
        <source>
            <dbReference type="ARBA" id="ARBA00048510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="39">
        <source>
            <dbReference type="ARBA" id="ARBA00048636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="40">
        <source>
            <dbReference type="ARBA" id="ARBA00049398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="41">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="42">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="43">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="44">
        <source>
            <dbReference type="EMBL" id="ODM99680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="45">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="854" mass="96475" checksum="103898E661E728B0" modified="2016-11-30" version="1">MLSPQQVPVQILNAARDNISLTTVKPNNNISFLSTIERPIEYCPPNETLVPHILRDGGVSQCFAETISSSVTLGFILLFGTIQFFFYRKYAIEVQHYTLPYSRLFGLQMMLNGLMPLVVFGQVAVKVFLGDPQAVYGYMLLSLIQGLLAWPLVCVLVIRERIYMLPAPPARGHGVILLMFWTAAFAFENLALLNIYSEDWFFKLKNPKDIVLLSIYVCKYVFTGGVFILGIRAPGIPTVRHSESFTRLHPNGDDEQRGTVSSGSAFGNLRHKIKLLMPFIWPSKSLALQFNVLICLVILVAGRVTNLFVPIYNKKIVDSMTLLNSSSSDDRTFSFSFGAGPSHLAFRWDFVLIMVGLKLLQGGGAGGTGVLNNFRSLLWINVEQYTTREVQIEFFGHLHRLSLRWHLQRKTGEVLRAMDRGTDSINNILNYLLFSIFPTIADIIIAISFLTSSFNVWFGLIVFIAMVLYLICTFAVTEWRTKYRRTMNLSDNEQRQRAIDSLLNFETVKYYANENYETKRYSESILKYQKEEWKVTASLCILNFLQLVIINGALLIGSLLCVKMVVYHEGFTVGDYILFTTYLMQLYAPLNYFGTYYRMLQKCFIDMENMLDLFKEEEEVKDAKDARDLIINSGVIEFRNVCFSYIPEKTVLKNVSFCVPAGQSVALVGPSGGGKTSIIRLLFRFYDPVSGDIFIDGQNIKVITQQSLRKTIGVVPQDTVLFNDSIKYNILYGKVGSTEHQMFEAARCAHIHDRIASFPERYDTAVGERGLKLSGGEKQRVAIARTLLKNPAIILLDEATSALDTHTERQIQTSLQRLCANRTSIIVAHRLSTIVDCDQILVLKDGCIVEGGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-10-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3D9</accession>
    <name>A0A1D2N3D9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemicentin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000255">
        <property type="protein sequence ID" value="ODM99789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3D9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013151">
        <property type="entry name" value="Immunoglobulin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00047">
        <property type="entry name" value="ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="59"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="168" mass="18656" checksum="5FA00AC97F791864" modified="2016-11-30" version="1" fragment="single">MYRSSVSVVPGIDSKIRISGVINNIDLEVESVDCFAPIWNSVKWEKRTLKLKITPSALPEFENPQDELITLKLNETGIYLNCSVVNTVNEQFVTTKLSWEKDGKRIFGWNENVGQVLQTFGGNTTESSVELFIISHSSAGTYTCTASNIKGKAMKKFAVFVDDGKSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4D1</accession>
    <name>A0A1D2N4D1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DEP domain-containing protein 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000234">
        <property type="protein sequence ID" value="ODN00091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4D1"/>
    <dbReference type="STRING" id="48709.A0A1D2N4D1"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16206">
        <property type="entry name" value="DEP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16206:SF4">
        <property type="entry name" value="PROTEIN LET-99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="633" mass="71563" checksum="121BA1B5B28DD5AE" modified="2016-11-30" version="1">MARPNSRTSSEVCHVNYPGFENDVFKLITDYFTSYNGCPLLTYELYDAFITTFIRAELFDFNARLYSCKTTSTSRSRLCHQLNLPYSTTVGNRTPIPNNLATEDQYPFNASESVENLIMDILTPAAIREAARRGRGITSKIQPKRILPVSAPALEVSMNPMEDSVLKSVPEPMSAKSYNADRYRNPFFFETAFTGVNSPVTRVVSETELKSTFCTLPRKGSTVQVGPMSTPPRYVYENPGLDLSASDMIYHPKYSRILKSTDIVNVSPTPNYSFYNYSNQSDSFGSSDASFHRSLPQRSHSSANLSDAYRDRSPYIPGAGRMLGRNPQGIAAEYAKSPSKSARRTLDYYYGADACVPGLMTPEGKRMAVASFRLLTLLLPPSRRKHLQILLRFMSKVAKNEKLMLDVAMTSRALIINVFFKIILNSADVREFDELLALRIVTFMVDNDADIFAISEESELVQQVEEIISEEQITKVPAKDEITPTAPQPQQLTSSSSSSLKQIKSRSKSKIKRLSSENKENQNVKLTYCYPISVDDYEGQKLLGSGGTSQSLRTLLDGIVTDPKIDHEFRRRKLLEQFIFTPISHFKKEYPHIYREKYGNSEPELLLLNESLKEEKPKERRAFSALLKPFRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4P3</accession>
    <name>A0A1D2N4P3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_06433</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000221">
        <property type="protein sequence ID" value="ODN00238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4P3"/>
    <dbReference type="STRING" id="48709.A0A1D2N4P3"/>
    <dbReference type="OMA" id="WTNDETK"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18010">
        <property type="entry name" value="DEXHc_HARP_SMARCAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010003">
        <property type="entry name" value="HARP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF6">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07443">
        <property type="entry name" value="HARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51467">
        <property type="entry name" value="HARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HARP" evidence="8">
        <location>
            <begin position="35"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="155"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="422"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN00238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="630" mass="70971" checksum="37FA0DC72E9F5A3A" modified="2016-11-30" version="1">MSVQLVKPLTSNSWSSSSSSNNTEVRQPFAQPAITSRTLAGSCVLVSRERFMVEIGYYRQLLDIFRSIDGHQYGSLLAHSQTRKWTFPLSEHTKLINAVAPLRPAVSIGPLPNFVQRVFQNVQPGVPRKIPTTDLDGVDKTLLAALMPFQLEGVMFGVSRKGRCLIGDDMGLGKSIQALGIANYYRTDWPLLIVCPSSVRYAWRDYIWKWLPNVVPSGSISIIESSKDQFDCAEILITSYDMLQKRSVEFSHCRVVIMDESHHLKNHKTARTKAAIPLMQTARRLILLSGTPALSRPIELYSQISAIDKSIFPFLNDFGVRYCDGKKNAWGWDFSGSSNMGELQLILEETVMIRRLKSEVLQQLPSKLRKVMLLDPSLVRTKNNKSLKAREAAFSSKGLKNSERRGKLLEYYAETASAKLDAVNAYIKDLINDDKKFICFAHHKSMMDGICAMLEEIKTRYIRIDGSTTAQDRQHAVDLFQHREDVPVAVLSITAANSGITLTAAKLVIFAELYWNPGILTQAEDRAHRIGQMDSVLVEYLLAGGTADDYLWKMVQDKLNVLNRAGLSKDNFSEVDATALVQRGANSDKQTKMEDFFSSQEKMEVEEYKECKDLENDQVLLDQLLDESFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4P4</accession>
    <name>A0A1D2N4P4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein SCO1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06446</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000221">
        <property type="protein sequence ID" value="ODN00247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4P4"/>
    <dbReference type="STRING" id="48709.A0A1D2N4P4"/>
    <dbReference type="OMA" id="MLYFRVE"/>
    <dbReference type="OrthoDB" id="270009at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000013">
        <property type="entry name" value="Blast:Protein SCO1 homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151:SF5">
        <property type="entry name" value="AT19154P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="182"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="35266" checksum="E8D43985564B80E3" modified="2016-11-30" version="1">MMSYVPTALSLTASRTLLCRPVGYQRLIQFQKATFSRSLVMNYSGLCSCSSVIRKMPSPCKQLFPLLNGSLQSCHFSSAAPESKDSPPLQPPTKDKSKADQKVSPISWRSVGLAATVGGFMLGFMIYLKREKEMAIAKERKKALGKAAIGGRFDLIDHNGKPCKSEDFLGQWALIYFGFTHCPDICPEEMEKMAKATDIIESTTDIKISPLFISVDPERDTVPAVAKYIKEFSPKIIGLTGSVEQVQKACKAYRVYFSAGPRDEEDDYIVDHTIIIYVVNPDGEFVDYFGQTKTAKDISDSVLISSEKYKAMKSKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N533</accession>
    <name>A0A1D2N533_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N533"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905045" evidence="1">
        <location>
            <begin position="23"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="320" mass="35737" checksum="E0B99EB165BF6BF8" modified="2016-11-30" version="1">MATVRKMTTFSVLLSLIGWTSAFVFQLNTNSKPQKEMTAPAESELFEKFYNEYFSRQESFFTEAKELAKAGESTDASCKTCNFVGGDINTCFADCITKKVGSYQNLAENIADTVKTMFCKPLGLKMDKFFGGQEGKGNPIWRDFKTFAQRVKKQLKSSVPLQNVVESWISNVHLLDESPMHVYSKVRTQISDLFDESEMDMANPNSFTAKCNSKDLSAGLSTLIGAGKQKGYVMDILFRGLFSVRSSLFYTFGNPTNQFGSFLEGLNAMVGKNCDLISYAMDEGSSESNCDSLGHYPNFDFPFPRDLIHLAPKCPEEGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5F0</accession>
    <name>A0A1D2N5F0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Neuropeptide Y receptor type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_06172</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000202">
        <property type="protein sequence ID" value="ODN00510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5F0"/>
    <dbReference type="STRING" id="48709.A0A1D2N5F0"/>
    <dbReference type="OrthoDB" id="9046662at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042923">
        <property type="term" value="F:neuropeptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004983">
        <property type="term" value="F:neuropeptide Y receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15203">
        <property type="entry name" value="7tmA_NPYR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000611">
        <property type="entry name" value="NPY_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235:SF29">
        <property type="entry name" value="GH23382P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235">
        <property type="entry name" value="NEUROPEPTIDE Y RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01012">
        <property type="entry name" value="NRPEPTIDEYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="71"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="441"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="559" mass="62183" checksum="7AA811CC5E003B0F" modified="2016-11-30" version="1">MELSWSNEERSTLNVDTFTTEYTEAELHNMNQSHYDHYSNYTLGDDIISHPAVQAIFYIVYATIFVLGIFGNVLVCFVVGRNKAMQTVTNFFITNLALADILLCALAVPFTPLYTFLGEWIFGRVLCHLVAYAQGTSVYISTLTLTSIAIDRFFVIIYPFKPRMRLTTCLLIITGIWVFALLATLPYGIFLHYKLDEDTCKYTCSEAWPSEGTRQVFSGFTVTLQFILPFIIMLFCYIKVSIKLSDRAKAKPGSKNSKKEALERERKRRTNRMLIAMVFIFGMSWLPLNVVNFLNDVYIDVADWKYSNLCFFFAHAVAMSSTCYNPFLYAWLNENFRKEFKQVLPCFHASSQGNSNRSKRFVSQRNCNGAETVQESLMPTTSQAITTTVNTQPANTTVIQVLETIDELNSSSQSAPVVAVDLNKACASFTTDTNEIIVHFPSSTPEKSSRPGGNHEGFDNNSAAVSSNNNKNVGKSGEVGKENNSTPAKSLTTITIEGNKANAAGLSSPVPNAKGKTKDSIESLAKVDAVVHSFEEDPCGNPSPDMINLKTFAVNTVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5H0</accession>
    <name>A0A1D2N5H0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phenoloxidase-activating factor 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prophenoloxidase-activating factor II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_06162</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000202">
        <property type="protein sequence ID" value="ODN00518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5H0"/>
    <dbReference type="STRING" id="48709.A0A1D2N5H0"/>
    <dbReference type="OMA" id="DICEQRM"/>
    <dbReference type="OrthoDB" id="6656697at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000038">
        <property type="entry name" value="Serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905064" description="Phenoloxidase-activating factor 2" evidence="7">
        <location>
            <begin position="23"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="266"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00068096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00076468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN00518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="509" mass="52997" checksum="4FEB37C7E6E42D9E" modified="2016-11-30" version="1">MWRIAEYFQLLVIIAIFAHCHGQGKSVKIVNEGANGTAPRLGLLASTLGVDPVPGYSGSSATAPAGGIPSQDYLPTGGAPALEQYTSDGGGIQGGNLVSSNQCQCVPVEYCPSLGGGQGQQQGGVFPIPGGGGSHEGGQQEGNLPVIGGGDGNYAGGQQGGNLPVIGGGGDGSYGAGQGGNIPGTDPGLQPGYGPGDQPNTDGAGLLDLRIVNRPPRPGGVQCLPGQVFCCDGQNPGPNPGPGGTGYTGYANCGSRKYIDVPSKKLEYGEAKFGAYPWMAVILGKGNNYVGAGALISPNFVLTAAHKIKSWKPGATMKVRLGEWNAKEDDEPYKNVEVPIESVLIHPGFNIDNLQNDIALVKLAKPVDTKAYPHIEAACLPQKGYEYTGQRCFVAGFGKDAFGNGKHSYIMKEVDLPIVDQDICEQRMRTTRLGPHFNLNRYSFLCAGGEEGKDACTGDGGSPLVCNTGKWQVVGLVAWGIGCADYGIPGVYVNVPNYADWINEEIYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N661</accession>
    <name>A0A1D2N661_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000190">
        <property type="protein sequence ID" value="ODN00712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N661"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905091" evidence="1">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="166" mass="18896" checksum="37ED8A583214EC10" modified="2016-11-30" version="1">MRALVLIVIVASVAISTTAIPSEEEKDLESQTRQKRGGWGYEPSNYVVAPGQHLTVVSPQKTISTTSVVHAPVAATTTLVHQPAVVVPQTESYVWQSSPDVTYSLHQRHGPRYSYYSSYPNYNYYPSYNYPNYNYYPNYNYYPTNNLLGHSPYLTSSPYYYSGWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6H8</accession>
    <name>A0A1D2N6H8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoredoxin-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6H8"/>
    <dbReference type="STRING" id="48709.A0A1D2N6H8"/>
    <dbReference type="OMA" id="MRENCEF"/>
    <dbReference type="OrthoDB" id="189920at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="2">
        <location>
            <begin position="66"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="215" mass="25564" checksum="AF67D0DD39D2FF0E" modified="2016-11-30" version="1">MAMTKCNVSYWILMSKHRILNTSLVPMKVMSHNINSWWRDPSLILYNKYYEPDEEISQYMRENCEFVGIFFGSFRNKSTKHFITYLNKFYRYVQQRDDPFDVIYVPLDEDEAECDFFVNSCMEEWLVVPWSNQTLRRNVRNLYNVLTQPWLVIVKNDENGTVVSYDGKLDLMECGYFSLIEWKSMYKKVLEDIKAGKDKKKPAAAPAPQSPDEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6I6</accession>
    <name>A0A1D2N6I6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Low-density lipoprotein receptor-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6I6"/>
    <dbReference type="STRING" id="48709.A0A1D2N6I6"/>
    <dbReference type="OMA" id="WICDNEN"/>
    <dbReference type="OrthoDB" id="9990982at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005041">
        <property type="term" value="F:low-density lipoprotein particle receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF5">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905116" evidence="4">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="223" mass="24673" checksum="B88AAC4FB70D3B2E" modified="2016-11-30" version="1">MKFIISLIGLCAVFGLVYSHYTPERSQACSETEFTCQDSGRCLPASWICDGDFDCGEDDMTDEQNCVPTTPAECTEFVCPNGRCISSAWICDNENDCDDDGDGSDEVNCPEMSSTPCSGFVCPNGACIPQQWTCDGDNDCGDEDFTDEKEEACPCADNETRCPQPSDSETPGACKNRSDEANCTATFNVNEPHYRPETVEARKLQRKMKKNRKQVLEKSNKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7S2</accession>
    <name>A0A1D2N7S2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G protein-coupled receptor kinase</fullName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_05410</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[G-protein-coupled receptor] + ATP = [G-protein-coupled receptor]-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12008"/>
            <dbReference type="Rhea" id="RHEA-COMP:11260"/>
            <dbReference type="Rhea" id="RHEA-COMP:11261"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000163">
        <property type="protein sequence ID" value="ODN01281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7S2"/>
    <dbReference type="STRING" id="48709.A0A1D2N7S2"/>
    <dbReference type="OMA" id="KSVDWQM"/>
    <dbReference type="OrthoDB" id="354826at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004703">
        <property type="term" value="F:G protein-coupled receptor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000118">
        <property type="entry name" value="G protein-coupled receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000068">
        <property type="entry name" value="G protein-coupled receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000239">
        <property type="entry name" value="GPCR_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF18">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00717">
        <property type="entry name" value="GPCRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RGS" evidence="13">
        <location>
            <begin position="54"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="153"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="14">
        <location>
            <begin position="417"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="11">
        <location>
            <begin position="519"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600239-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN01281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="656" mass="74528" checksum="10FA21F824CE1D65" modified="2016-11-30" version="1">MADLEAVLADVSYLMAMEKSKGTPAARASKKIILPDPSVRSVMHKYLEKKGDVTFDKIFGQKLGYLLFKDFCENVVEEPIPQIKFYEEIKKFEKMETVDERRKAAREIYDNFIMKELLSHTHNFTKEAVDHVQKHLIKSDVPQNLYELTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGADCPFIVCMTYAFHTTDKLCFILDLMNGGDLHYHLSQHGVFNEQEMRFYAAEVILGLEHMHKRYIVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLSKGTAYDSSADWFSFGCMLYKLLKGHSPFRQHKTKDKHEIDRMTLTMNVELPESFSTELRSLLEGLLMRDVDKRLGCKGRGAEEVKEHPFFKGLDWQLVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLESDQDLYKNFPLVISERWQAEIAETVFDTVNTEADKIEMKKRAKHKKGYDADEKESDCILHGYVKKLGGPFASAWQTRYAKLYPNRLELHPDSGSTKPELVFMDCVEEVGGELLTVKNEQSVVIKMKDQNKVVVTSSDEIGLNEWAISLRAAHKNSLELLSSMARKAGKIYGAEIDSNSKNSPVVNRSANGGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N808</accession>
    <name>A0A1D2N808_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_05575</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000170">
        <property type="protein sequence ID" value="ODN01106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N808"/>
    <dbReference type="OMA" id="THMQPIN"/>
    <dbReference type="OrthoDB" id="8251402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000006">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000001">
        <property type="entry name" value="Leucyl-cystinyl aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000006">
        <property type="entry name" value="Puromycin-sensitive aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 22" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9 16" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905179" evidence="18">
        <location>
            <begin position="20"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="21">
        <location>
            <begin position="47"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="19">
        <location>
            <begin position="284"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="20">
        <location>
            <begin position="587"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="19">
        <location>
            <begin position="977"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="20">
        <location>
            <begin position="1237"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="17">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODN01106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1530" mass="171333" checksum="E9FCDD25E963CAA8" modified="2016-11-30" version="1">MEQAKIVLIILSILGGISSSPPLREVSPEFENFEEIIPLYKLPDSLVPSYYNVELQPILDEGYGTRFTAPGKVSINVLCLFATNNITLHALTLNISESSVQVREIVGGSEIPIASFDVDAEKDFFIINLQNGLRAGAVYQIYIEFVAPVSREVLYGLYLSNYTADDGSTRYMAITDLEATDARRVFPCMDEPSKKAEFEISIIRLPKYSSLSNMDLLRTETEGPGIPQGWVKDMYKRTLKMSTYLFAVAVSDFEVEEAAPGHYTKPVKVWGPPPYMQAGAGKYSPDLTAKLMTALENYFRVPYTFPKMDKISVPHFGGGAMENWGLNTYRLNRLLIEDGIATESDKISTAITLSHELVHQWFGNLVTLKWWDDLWLNEGFASYYSNTVLIDVGLEDILPLDTLVSDAIQRAMYYDVTSATHPVHYNVTTPTEIRIMFDTITYSKGCAMVRMMEAILTEPVMRDAVTAFLTKFEYNNAQQDDLFQVIDDQATSLPGTDLTMKAVMDTWTLQSGFPVLYVSRTEGSGSITFRQAKFKTDLNNDDDPTPSSWDIPISLYLPTDVQVNTSAVLWLKKDAPIEFFSIANVQWFIINPRQTGYYRVNYNRASIRPIIEQLHTNHEAFDPQTRSALIDDNLNLAYAGYSDLTDALNLTMYLKNERHLVPWTTFVTNMAKPYRFLSRTAGLSAFKKYIVGLIKDTLTEINIDPQPNEPIGNATILRNKLFEWACNLDDSECIQYSKNKFAQWMTDPSNNTIIFPDLRPFVYCAAVANGGDAEWDFALAQYSAANREVTKTNLIRSLACSKSVFRLARFGVSMISSVITTLSNTLNKAYDITDIQRFIRDNEPALQPVNGTLQTAIGNIENNIKWSITLTATPDQPLTVTGVTEDDERDFYIIQLESEIAAGAEVSIQMEYVAQIPTSGAGLFYREYQTETGEVRRLAATQFESVEARRMFPCFDEPDLKAVFELTVIRKDNYTSLANTELVSSTPENLVTLIITHELAHQWFGNLVTLKWWKEVYLNEGLTTYSQYLGMEAVSPDLMGVEFAILDAFQYSMLYDASEYSHPLSNDVTTPDEIDGMFSTISYEKGASVIRMVDGFLTRETLRKGLQAYLKKMSFQGAQQEDLFESLEEAAVADNRLPAGLNMADIMSSWTLQSGFPLVRVQIANETAITVSQERFLNDGAEDPEGSSWFVPITIVTADNPTLENNIPQVWLEKDVSSKAVAHDVSKWIMINQNATEYVSIEAALNLTRYMEQETHFAVWSTFFEHFNNIYVKMASHPGYSLLRDYLVPKLDAALTAVGVEESPSHTGALAILRADLLDWACSLQSPLCFTYANQLLAQWVDNPNTSPILSVDARATLECAIVAAGGKPAFDFVFAKYQDSGSNTELKNEFLNALACTTEISVMNELLNKTLNTTSGIAPGDASSVLNSVSSGALGRTIILDFLSENLEDVITVIGNGGLQPITGVLGTLQNYFTTKAQLDKLEAFVAAHQERLTPINMAIRLVIQRIQDNISWMDTTGFDIWMWLWFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N818</accession>
    <name>A0A1D2N818_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deleted in autism protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05569</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DIPK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000170">
        <property type="protein sequence ID" value="ODN01116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N818"/>
    <dbReference type="STRING" id="48709.A0A1D2N818"/>
    <dbReference type="OMA" id="LWAACYI"/>
    <dbReference type="OrthoDB" id="10035316at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020519">
        <property type="entry name" value="DIPK2A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022049">
        <property type="entry name" value="FAM69_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32073">
        <property type="entry name" value="GH11358P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32073:SF7">
        <property type="entry name" value="GH11358P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12260">
        <property type="entry name" value="PIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="FAM69 protein-kinase" evidence="6">
        <location>
            <begin position="205"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN01116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="435" mass="49273" checksum="F5D891B6D80DAD4C" modified="2016-11-30" version="1">MKTRQRWILLVFMAMTAILLLVMWTGGITKSPAFMTASPISLTVDLDQLSDRDKCPACFGVKMCPQIVNGQIKLKHWTKYKVTRYVNQKNIFYGQWDDGFGQREVILKKLAHDHELDALDRTICERHGRDQNCDVADTVRFLIEEYSHHSTLRPGEQILHGEKIGNGSDILLCPSHAKMDFLIDAATKFNKGQHKKTILANVLTNILVNPEPILLEAFPASKGWPFPIFYGACGRLVVEEYVGQPLSSFVDKPFKVRAYLALQLLKMANLFYENPTQYIIYLTDPQADNFAVVENTNIVKLVDLENLMVVDKELLIQSKAKDADKLAVSESVTCEDQGRYTKECFSYSVDDLCDRPRIDHNYYAVCAGLLAPGLSYDFPQGLLHSLPDEDSDKLQSLPGMLLQCKNPKLGKLGLNRIEAAQRLIEILDSYLEHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N924</accession>
    <name>A0A1D2N924_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein ERGIC-53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04910</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000139">
        <property type="protein sequence ID" value="ODN01763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N924"/>
    <dbReference type="STRING" id="48709.A0A1D2N924"/>
    <dbReference type="OMA" id="WSAEFQF"/>
    <dbReference type="OrthoDB" id="10265193at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06902">
        <property type="entry name" value="lectin_ERGIC-53_ERGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000028">
        <property type="entry name" value="Blast:Protein ERGIC-53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905233" evidence="10">
        <location>
            <begin position="23"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="11">
        <location>
            <begin position="27"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="266"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="505" mass="56360" checksum="42778AA5E47457A8" modified="2016-11-30" version="1">MASLVELLVNFLIISPILNALASEPFKRFEYKYSFKPPYLAQKDGTVPFWEHSGNAIASEENLRITPSLKSQKGRIWSKIQTNFDWWEVELVFRVTGRGRIGADGLAFWFSEVPGGDGPVFGSNDMWKGLGVFFDSFDNDNKHNNPYIMAMVNDGGKVYDHQNDGSTQQLAGCLRDFRNKPFPVRAKMHYYRNIFTVMFNNGMSNSETDFELCMRVENVYLPSRGYFGVSAATGGLADDHDVQKVLTFSLHDDQTGQLTDAHQVEQQKFDQEFQRYQEELDKKKDEYIKEHPEAQKEKDDEDWFEEEQIRELRQIFQGQSELRGLVQTLSRKLDEIVGRQETTISLVNTISQGGGGIPHQVAGQVPAAIPQVAAPGAGVLQRHEVENILAASRELVAATREIKNLIVGVGSKIDTANARPGSYGNVDITGSVNELKDGINILKRDIGTVSQRVHAAPVAAGQEGCPNVSCVSTTVVVAMGFVQMGVILGYLLYKSSKENQAKKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N937</accession>
    <name>A0A1D2N937_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Homeobox protein rough</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04916</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required to establish the unique cell identity of photoreceptors R2 and R5 and consequently for ommatidial assembly in the developing eye imaginal disk. Repression of expression in R8 photoreceptor by senseless (sens) is an essential mechanism of R8 cell fate determination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000139">
        <property type="protein sequence ID" value="ODN01769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N937"/>
    <dbReference type="STRING" id="48709.A0A1D2N937"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048663">
        <property type="term" value="P:neuron fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000417">
        <property type="entry name" value="Even-skipped homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050848">
        <property type="entry name" value="Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000047">
        <property type="entry name" value="HTH_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333">
        <property type="entry name" value="HOMEO BOX HB9 LIKE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333:SF8">
        <property type="entry name" value="HOMEOBOX PROTEIN CEH-62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00031">
        <property type="entry name" value="HTHREPRESSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="11">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="8">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00068739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="233" mass="25684" checksum="993782A625E652F7" modified="2016-11-30" version="1">MMARRRRRDGRARRQRTTFSNEQTLALEVEYQRAEYISRSRRCELAQRLSLTETQIKIWFQNRRAKDKRLEKAQADQQVRCLASSIALHGIATGNSGSTSISASSLSTTLQEGTNILSQRSMSNPSIPSHNPLMIPYLAAGYLPLHQLALGLSLGPHQQTKGSSKMFSVAGPTPPTTPSGRDVLRKGDESMEDAVTWSPPTVFRSSHGNNGQIPNISVNTTAMALTSLAHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9F3</accession>
    <name>A0A1D2N9F3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000136">
        <property type="protein sequence ID" value="ODN01874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9F3"/>
    <dbReference type="STRING" id="48709.A0A1D2N9F3"/>
    <dbReference type="OMA" id="RTRWHIS"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14016">
        <property type="entry name" value="STKc_CK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="202" mass="23996" checksum="D663FD911E83C8FC" modified="2016-11-30" version="1">MLADQLLTAVEYLHGKSFIHRDIKPENFLMGVGPNRNKVFMIDFGFAKRYRDQRTRWHISKSRNNPLIGTARYCSINTHEGKEQSRRDDLESLGYMLIYFLRGSLPWQGLKGANKKQRYNKIMECKISTSIEELCKDIPKEFGTYIFYCRCLKFDERPDYKYLRQLFQILFKRRGYQNDNTFDWTFLEEKESKLDPAGPSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA24</accession>
    <name>A0A1D2NA24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Follistatin-related protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_04568</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA24"/>
    <dbReference type="STRING" id="48709.A0A1D2NA24"/>
    <dbReference type="OMA" id="EVARREX"/>
    <dbReference type="OrthoDB" id="6085115at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019577">
        <property type="entry name" value="SPARC/Testican_Ca-bd-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10591">
        <property type="entry name" value="SPARC_Ca_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="319"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="798"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="18"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="197"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN02108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="829" mass="93064" checksum="A213979025AA8CC4" modified="2016-11-30" version="1">MKLDALLIYNHQHLIGDIPSKKRKSGNSRKHLNHSHSSNSGGRRMKSTASKRNDNDEDEDDDSNEDGNDERQQQQRNSASGLHHDDESTFQKEYLLSLMFAHFDQNNNGKLDYAELQKVGMEQKIVPTVHCHLVDFLRYDDMDSDSLISPNEFYTAFSKLYSMSILGAGKPRAPIHLTARVGEVLEIKCSVGAGSVSSPTGRRKFSASKREVDAGVNDDGTGNEKEDDLEYPIFAARSNDRNERNSRKASSMLPTTQWYRYGVDVSKLMNLGEQFQIHKDGTLLINRVELIHAGNYSCHDDKGNEKVIQPYVLAVQMVPEVKVRPHMEWVQWLQQPGQEVSMECRAQGEPLPAVRWLKNDNPVIPSKDKYTIAGDGITLKVKDINFSDTAAYTCSAQNEAGKRIDISSLVVIDEPALPPVQFNESQFLVFHERGISTYDPDNCRIQNEIHAIDIIPGTQRDYICGSSNPSSCEWGSVIRVSSVYIYASQPKMNRVLIISMKQLIVVDVVQTDRYPVGLSYVSHFDQVWIECWKEEERYTTKTLQVIRGAKEKKKHRAVRPKPLVSLEADLVQNVFLPPATSPFISSSPSPATASFRHAYISHKNTRGLYKMDLRTLRYTKSIDLTSYNCLPEQVHFTALYGFIILECKEPVLHQPTGQLVLDSISDAIIAYKADLNGASFLSPDSRKLVTMVQNRHDRSSGTTLLLQHLDANGVRTIFDVNTSLNISDIAFFPSQTSHTYDLYATAVHEESVLFVDLHSGNVELVPGVGKAALKNPSYERPQRMIASEDLFGKYLVTPSSDAVYVVNGQSHTVNCQIGGMTNPNMVVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAA9</accession>
    <name>A0A1D2NAA9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000122">
        <property type="protein sequence ID" value="ODN02182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAA9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905286" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="7995" checksum="54CFDAD60883CA18" modified="2016-11-30" version="1">MISKMFPRVIALLVLAVCAMFAVATTQTTQVPKTRGNINDQQLAQSLGIDRQVLYEDLVAIQDDVSRLQAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBM8</accession>
    <name>A0A1D2NBM8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Myosin-VIIa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_04025</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000101">
        <property type="protein sequence ID" value="ODN02660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NBM8"/>
    <dbReference type="OMA" id="TGFQGRC"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120025">
        <property type="term" value="C:plasma membrane bounded cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009888">
        <property type="term" value="P:tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17093">
        <property type="entry name" value="FERM2_F1_Myosin-VII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd13198">
        <property type="entry name" value="FERM_C1_MyoVII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13199">
        <property type="entry name" value="FERM_C2_MyoVII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01381">
        <property type="entry name" value="MYSc_Myo7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.10:FF:000012">
        <property type="entry name" value="Myosin VIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000079">
        <property type="entry name" value="unconventional myosin-VIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000051">
        <property type="entry name" value="Unconventional myosin-VIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.530">
        <property type="entry name" value="MyTH4 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002404">
        <property type="entry name" value="IRS_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057130">
        <property type="entry name" value="Myosin_VII_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041793">
        <property type="entry name" value="MyoVII_FERM_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041794">
        <property type="entry name" value="MyoVII_FERM_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036106">
        <property type="entry name" value="MYSc_Myo7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000857">
        <property type="entry name" value="MyTH4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038185">
        <property type="entry name" value="MyTH4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051567">
        <property type="entry name" value="Unconventional_Myosin_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692:SF33">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692">
        <property type="entry name" value="MYOSIN VII, XV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21998">
        <property type="entry name" value="FERM_C1_MyoVII"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02174">
        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24123">
        <property type="entry name" value="Myosin_VII_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00784">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21989">
        <property type="entry name" value="RA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00139">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51016">
        <property type="entry name" value="MYTH4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8 12" id="KW-0518">Myosin</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="Myosin motor" evidence="17">
        <location>
            <begin position="80"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="MyTH4" evidence="16">
        <location>
            <begin position="1019"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="14">
        <location>
            <begin position="1474"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="domain" description="MyTH4" evidence="16">
        <location>
            <begin position="1618"/>
            <end position="1766"/>
        </location>
    </feature>
    <feature type="domain" description="FERM" evidence="15">
        <location>
            <begin position="1772"/>
            <end position="2075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="12">
        <location>
            <begin position="629"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="961"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="173"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN02660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2084" mass="240666" checksum="F1C39323879BD57C" modified="2016-11-30" version="1">MARQFVDPEKANEELMNKQVFILGDYIWIEPASGREFDVAIGAKVISAEGRRIQVRDDDGKEIWLTPERRIKAMHPSSIQGVEDMISLGDLHEAGILRNLLIRYNENLIYTYTGSILVAVNPYQILPIYTAEQIKLYKDKKIGELPPHIFAIGDNSYANMKRYGQDQCIVISGESGAGKTESTKLILQYLAAISGKHSWIEQQILEANPILEAFGNAKTIRNDNSSRFGKYIDIHFNKGGVIEGAKIEQYLLEKSRIVSQNPDERNYHIFYCMLAGLTKEEKAKLSLSEPTQYRYLTGGKCITCEGRDDAAEFSDIRSAMKVLMFSDPEIWEILKVLSALLHLGNIKSKGTIINNLDATEISDSSHVETTASLIGVNRQSLIEALTTKTIFAHGETVVSTMSREQAVDVRDAFAKGIYGRLFVWIVSKINSAIFHPRGGVHMSIGVLDIFGFENFESNSFEQFCINYANENLQQFFVRHIFKLEQEEYNLEGISWRHIEFVDNQEALDLIAIKQLNIMSLVDEESRFPKGTDTTMLAKLHKAHSSNRNYLKPKSDINASFGFNHFAGVVFYDARGFLEKNRDTFSGDLLQLIEISGNKFLQMLFHDDIAMGNETRKRAPTLSSQFKKSLDALMKTLSSCSPFFIRCIKPNELKKPMLFDRELCCRQLRYSGMMETIRIRRAGYPIRHTFREFVERYRFLISGVPPAHKTECKAATSRICAAVLGKTDYQLGKTKVFLKDAHDLFLEQERDRVLTKKILILQRNIKAWYYRRRFTRMRSSAVIIQKHVRGYLQRRRYLKMRNGYMRLQALIRSRVLAHRFKHLRGHVVGLQAVCRGYLVRRQCRRKLWAVLKIQSHIRRMISQKHYKRLKLEQRGKLEALRLREQEEKELKKQGNKRYKEIAEKNYRERLLALQRQEMEIDREDRLIIDKKKMAIENAARKQDEPVDDSKLVEAMFDFLPDNTSEAAPPSAFRDLPNPPKADEDIYSAPELQPADIEDLSEYKFQKFAATYFTGNANHQYSRRPLKSSLLPLATPADQLAAQALWITILRFMGDLPEPRYHSMERDTTSVMSKVTATLGRNFARSKEFQDLGLDNIDGYNIKQKPRSIRHKLVSLTLKRKNKLGEDVRRRLEGDDGAADSYQSWLESRPTSNLEKLHFIIGHGILRAELRDEIYCQICKQLTNNPSKSSHARGWILLSLCVGCFAPSDRFVKHLRAFIREGPPGYAPYCEDRLKRTFNNGTRNQPPSWLELQVSSLGSGNEHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEIFAPWHDPSEDSVATNLIYQQYRCDKEEDLAMIAAQQYYVDYGTELHSDKLNSAMTSYIPDFCLNSSDKSPERWTQLVTTAFRRSLHARERADLLRVKEDIVAYAKFKWPLLFSRFYEAYRYAGPNLPKNDVILAINWTGDKIFGQTFTLSTVRPGEEFTFQSPNAEDIRELVDFFLDGLKRRSTFCIAMQDYKPPNEGSSFLSFLKGDLIILEDDNSGETVMTSGWCVGRCERTDEKGDFPAEMVYVLPATAKPPPDILELFKTEDGGKRFIHAYTNGVDTLKEKPHTLEEYAIEHFRPPPKRTISKSLTLSSARRANRDELWRHSREPVRQPLLKKLQNKEGLVEDACFIFTSILKYMGDIPHKRSKIGNELTDQIFDAPLKQEILRDEVYCQVMKQLTDNRNKFSEERGWELMWLATGLFACSQTLLKELTQFLRTRRHPVAQDSLQRLQKTLKVGQRKYPPHQVEVEAIQHKTTQIFHKVYFPDDMDEAFEVDSSTRAKEFCANIAERLTLRSAEGFSLFVKIADKVISVPEGDFFFDFVRHLTDWIKRARPTRDGTIPQFTYQVFFMRKLWTNTVPGKDRMADLIFHYHQELPKYLRGYHKCTKEEAAKLAALIYRVRFDESKQELQQIPQLLRELIPSDLAKLQSPNDWKRAIVAAYNQDAGMSPEDAKQNFLKIIYRWPTFGSAFFEVKQTTDPSYPELLLIAINKQGVSLIHPQTKEILVTHPFTKISNWSSGNTYFHMTIGNLVRGSKLLCETSLGYKMDDLLTSYISLMLTNMNKQRSLRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC08</accession>
    <name>A0A1D2NC08_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC08"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="367" mass="41705" checksum="4D009F09E1171511" modified="2016-11-30" version="1">MATSNRPDYEIISAPFCTGVDGPPHGTNLFFTPTTCFESRDPTAKEDLDIAVLYAEGAAKIADLKYPKEMDSLTTAFMSYDEPLYPIPVGASVFYFVLIAWITTFYFTYLGRKVLSNLKQKLDLHPESNKFPNLPLCWLQQSKRESELRREVRNTWAHLAKRYLLSPNDPLLANVDQILGIVNWHDFEKCKNTWSLIKTVLRLNALFLKIRKTNADGRRSFEILRDRDLTRVPMDGDKVQRVFEEDDDMQSYIGDSLHYQTTESTIMTDSTITTAASIRKPDDSHMDPKLRQDHIQLSPSVRPIAPAHKTDKSKSVTLQKGQKPDFKSKGKVAISNKPTKNKSKVTTFNDEAIHHEDSSDQPFDGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCZ1</accession>
    <name>A0A1D2NCZ1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit H</fullName>
            <shortName evidence="4">eIF3h</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03838</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCZ1"/>
    <dbReference type="STRING" id="48709.A0A1D2NCZ1"/>
    <dbReference type="OMA" id="WYQSTYF"/>
    <dbReference type="OrthoDB" id="10265695at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08065">
        <property type="entry name" value="MPN_eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03007">
        <property type="entry name" value="eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027524">
        <property type="entry name" value="eIF3h"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045810">
        <property type="entry name" value="eIF3h_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19445">
        <property type="entry name" value="eIF3h_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="332" mass="37966" checksum="C922EF763E07B12D" modified="2016-11-30" version="1">MALRGRRNEFNCPYDYVQMDGLVVMKIIKHCYEERSNIDTPRGGLLGLVIENRLELTNTFPFPFTKAGEEAVDEEYTSAMMMHMKKINQDYLHVGWYQACELGSFVTTEFVLAQQGYQDSIEESIVVIYDPQKTDKGFLTIKAYRLTPQALKLLAENENTITPELVKSLHLSYERLFHEVPVVIRNSPLANALCCTMSEMKPAKATQFLDLGTASVMERHMHSLLEKVDELHQEAYKMNKWQMQVSKQQQEKAKYIHQRNMENATRQAKGETALPEEDLAKIFRPIPPPSRLPPMLASGQIEMSCQQVNSFCSQALAKLFISESLQESKTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND25</accession>
    <name>A0A1D2ND25_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Thromboxane-A synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_03563</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND25"/>
    <dbReference type="STRING" id="48709.A0A1D2ND25"/>
    <dbReference type="OMA" id="CHEKYGE"/>
    <dbReference type="OrthoDB" id="8251073at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF102">
        <property type="entry name" value="CYTOCHROME P450 FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN03152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="443" mass="49512" checksum="993BAE41C8EA12ED" modified="2016-11-30" version="1">MQFGPICGYYMGAKPVILLAEPSLIHSIQVHPDFLDRPRRVPGGINPDPNRAKMLGNLGVSEWKDLRGILDKAFSPKKLKAIQQNVQELINTFMSKLALAEPADSVNFYPLYQNLTLDLIGKTGFGIDSDIQTNPNDALKRAVDQEFSKATGTSLLKFFLCFPEFHGVLQPIRVVWEKVKIRLGIAGHSELWKLGRKAVLERQINPQPDATDLLQVMLDSGKLDETSIVANSVLFFEAGFETLSAGLAFITYLMVKHPEAQEKVRAEIGDLIEKNGAKLDCYKLKQLKFLDQCINEALRMYPPQTTFIGRSGSTDIFHEYELNGKQMKCVIPANVHIQVGLNQILNSDAIWESPRSFIPERHAGGAQNEETKHDQKSLFNPLEVGDECASVNMTLKMMLVSLFISYRLVPSDETEDDIAVIYKTATMTPKNGVFGKLIFDPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEU8</accession>
    <name>A0A1D2NEU8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glycine receptor subunit alpha-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_02912</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ligand-gated ion channel (TC 1.A.9) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000064">
        <property type="protein sequence ID" value="ODN03773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEU8"/>
    <dbReference type="STRING" id="48709.A0A1D2NEU8"/>
    <dbReference type="OMA" id="KHRAPKF"/>
    <dbReference type="OrthoDB" id="407674at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19049">
        <property type="entry name" value="LGIC_TM_anion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.170.10:FF:000024">
        <property type="entry name" value="Histamine-gated chloride channel subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00860">
        <property type="entry name" value="LIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="12">
        <location>
            <begin position="33"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="13">
        <location>
            <begin position="239"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN03773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="399" mass="46039" checksum="E88AFD41148EB417" modified="2016-11-30" version="1">MVTIKSILNCRPPPETRPGGVITLLDILPADHKSYDKNRPPKNNEQPTIVYFHVTVLSIDSINEESMTYVADIFLAQSWRDHRLRLGTGKMDDHYRILDVQWLNDIWRPDCFFKNAKSVTFHEMSVPNHYLWLYNDKTLLYISKLTLVLSCAMKFETFPHDTQFCSLQIESLSHTTEDLVFRWNKTDPLVVNPDIELPQLDIARNETEDCTLEYSTGNFTCLEVVFQLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARITLGVTSLLTLATQNTQSQASLPPVSYVKAIDIWMSSCTVFVFMSLMEFAVVNHFLGSGHPIDKGYEDIHDLNSIIDSQSRVWNFLGFKLSATTANFTNFCSNREIALGIDRVSRFFFPFAFVVLNVVYWCTFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGF4</accession>
    <name>A0A1D2NGF4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGF4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905520" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8981" checksum="32C9734D5B34BF6B" modified="2016-11-30" version="1">MRLLVLLTFLPVEFGWVSSGFGFIHENLWRGQLTAVLWIPFWDSEEEKLNSRVIPNASTTAFSLGLHTVHVQVITISNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGI0</accession>
    <name>A0A1D2NGI0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGI0"/>
    <dbReference type="STRING" id="48709.A0A1D2NGI0"/>
    <dbReference type="OrthoDB" id="6366898at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905522" evidence="1">
        <location>
            <begin position="23"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="166"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="329" mass="37323" checksum="69D1659DB68C6D64" modified="2016-11-30" version="1">MGLMQRGRLFLLLGFLISSASAQYGDTKGGRDVVTKVIRALCWYEFMDKVQTDVNQFLRCDNQVQKIKNGYEGAPDVVFGGALANSLPQWFPNYVRECDIFLKSPKRQFKGGIKKTNYGYVIGEHFSQPYSFQAFAHCLVAEVDKTNGAPAMLALESRLRGERYWRETMFRRENEFRTRHNVSNLELDTLLTEDAQMYAEQLARTCSFKPSNPMARDRLYSRQFTGENIAMNGGAFLRDEDSANVAVTGWYEEMANYDFATGASKSNLPVDQFTQSVWKGSKKVGYGMAMNKKCPNGYTHYIVARYFPAGNMPNAYLENVFPATTPLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGI2</accession>
    <name>A0A1D2NGI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein spinster</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02318</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGI2"/>
    <dbReference type="STRING" id="48709.A0A1D2NGI2"/>
    <dbReference type="OMA" id="YICAAGL"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17328">
        <property type="entry name" value="MFS_spinster_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="92"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="528"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="563" mass="61042" checksum="2902F75BBE7D7963" modified="2016-11-30" version="1">MANAPGMVSTASAQSPTGNGAVVIPEGEGVGRNRIPTNKSSQKLVNEDYLQPSSTRNSLGNGDGGGGDSIASSIDTTAGRRRSKISKMEWATVFILFYVNLINYMDRFTLAGVLDDVSKSFGINNGEQGLLQTVFVISYMVFAPMFGYMGDRYSRRVIMAFGVILWSVTTLAGSFMEGNFYWFIAFRAMVGIGEASYSTIAPTIISDLFLDDVRSKMLALFYFAIPVGGGLGYIVGAQAANLGGAWYWALRVTPFLGLIAVIFIIFIMVDPPRGEREGSTALKATTWGEDMKYLLKNKSFMLSTFGFTCVTFVTGALAWWGPKYIFYGLMLQNGGDQVKQTTVSFIFGVVTMMSGLIGVPLGALAATNLRTRFLKADPLICAFGLIVSTPLIFGGAILAKHNEALCFTLIFFGELFLNLNWAIVADILLYVVIPTRRSTAEAFQILLSHALGDAGSPYLIGKISDWIKPWLREGGPVSDEYVEFTSLQYALFVTVFVQIFGGILFLVTACYVVQDKRDCDGIIAASSGESITINPNPPPPPDEKANGESETNETGQGEGENEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGU2</accession>
    <name>A0A1D2NGU2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGU2"/>
    <dbReference type="OMA" id="PFFTHAT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="687"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="783" mass="84471" checksum="1DFC2B8A49D582F5" modified="2016-11-30" version="1" fragment="single">IFVQGAVLVSASPGLPQFVKAALGFRLGYSPTERGYNQKINYGAEKKGVGVQLLSGANNGGWHQGQQQGGLQAAGSGYGSGIGGGREGPLAAHVGHGAVKHLRILGLNLYLGGRAAHLAHGQGGQHHGHVGQGAQHHGHVGQGGQHHGYVGHGHGVQHKAPLLKKPLLLSPFKPLSALFGIRPSVHFGGKPSGAPHTVGGVTGLRAAVGTQDYGVGFKVGYRQGVNTKSTLAQVLTGGLGLGLGAAHGGTHGKYSYVPSVHKGQDQAYVHGNNLLKGHGHNQNNQYSGYGQLDSPVSGLESKHQFSTQLLAQGSQLQQLQPQGPIRIPYIPQHNGLRMVLAPNPQAHPQQHSRHNNNGQHWSTIFPSSSSSNGPHSAASNHFINPLPPNGQSLTKLQASLQGPVASAQNQIPYIQHQQPQRPHYQGYSLNGYQGPFAQPNNRYQNNFYQQPQQQQQSNHYSQQSSPQFPQEYNLFQQQSFNSPLQSFQNNAPSHYSQQPQQHNQQNPQSLNSQQTPFFSQIQEQPLSSPQQLEQHSQQQQQSQNLQSQNLQSQNLQSQNFQSQNFPNLPQIPFTADSMPFQPDPNFQYTHSTSSEPVSMGSYTMDMDISNQDSNNGNAPGPLVGPLGRRLKKAKRARADVIIKKSDTVEADTKDLETSASSNAILMASSLGSTSWTPLVMIEPPKLSKKSLETTPSIPEKKQQQEQQAVIKPKSQKIGASISVLPTVASTTNPSDHGQDDRSMILKKRRLNFSGEVTGPTVIPTTTLPLLLLHLPLLPPLPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH51</accession>
    <name>A0A1D2NH51_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Collagen alpha-1(IV) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02097</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Trimers of two alpha 1(IV) and one alpha 2(IV) chain. Type IV collagen forms a mesh-like network linked through intermolecular interactions between 7S domains and between NC1 domains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
            <location evidence="1">Basement membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000040">
        <property type="protein sequence ID" value="ODN04593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NH51"/>
    <dbReference type="OMA" id="ENINTGA"/>
    <dbReference type="OrthoDB" id="10071882at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005201">
        <property type="term" value="F:extracellular matrix structural constituent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009792">
        <property type="term" value="P:embryo development ending in birth or egg hatching"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.240.10:FF:000001">
        <property type="entry name" value="Collagen IV alpha 1 chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.240.10">
        <property type="entry name" value="Collagen IV, non-collagenous"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001442">
        <property type="entry name" value="Collagen_IV_NC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036954">
        <property type="entry name" value="Collagen_IV_NC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050149">
        <property type="entry name" value="Collagen_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023:SF1112">
        <property type="entry name" value="COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01413">
        <property type="entry name" value="C4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00111">
        <property type="entry name" value="C4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51403">
        <property type="entry name" value="NC1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0084">Basement membrane</keyword>
    <keyword evidence="6 11" id="KW-0176">Collagen</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Collagen IV NC1" evidence="10">
        <location>
            <begin position="1871"/>
            <end position="2093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="404"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="280"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="582"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="601"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="697"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="709"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1037"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1193"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1265"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1281"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1381"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1437"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1491"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1514"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1553"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1644"/>
            <end position="1653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00064856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2093" mass="203213" checksum="F87CB4FB2A65EEF7" modified="2016-11-30" version="1">MYSYVLHHVLERAPAAKTVNMIWEWDGQEHDRSSSNGIRTEDGSYFRRNGGSSRNGHGDDTYTYERNGDNGYTSRRDPFYAQEGASSSSYDPYARDRDRGDTSRYRDSDGGEGRPDSGLSYTGDSRGNGHGSSDGSDRSRSSSGGGSSSSHGGGGGADGDNGRYDTDDPYGSDPYGTEYENRRSGSSSYGGGATDSNYSYDPYASSRGGGGGGAAGGGGSYDPYASSRGGASGGDGSGAAGGGSGSYDPYASSRGGASGGDGSGAAGGGSGSYDPYASLRGGGGSSGAGGAAAGGGGGSYDPYASLRGGGGSSGGGGVAGGGGAAGVVVQLEVRSGGSSGGAGGGAAGSGGRYSNGTAQGADPYGSYPSSYYDSLRSGGRGGAPGNESACGGCCISRCVAEKGSRGGPGGPGVQGEKGQQGFPGMEGLPGPKGDKGDSGLQGPRGPKGDRGKMGMPGFPGIPGIPGLQGIQGPSGRQGLDGCNGTDGVPGVPGTSGGPGPRGIPGLPGDKGIKGEPAIARPGGKGQKGEPGLEGQTGPTGPPGTPGLDGTKGAKGDSGVSGLSGIPGNPGEKGEMGLAFEGQKGDKGDKGGRGPPGPPGNINGTYHTGNGTQFVGPKGEPGYKGERGDTGSAGPGGQPGSPGFPGLPGEAGMKGEKGLPGPAGPRGRDGYPGPVGPSGQKGDRGEAGLPGLSGMKGQKGDSGRDGEKGLQGLPGPQGPPGCLKGLAGPPGPEGPRGYIGLPGPKGEDGVAGLSGVIGPPGPQGGRGLPGRDGQEGMPGPKGEKGLSGLNGLPGERGTSGIPGQPGPPGFPGAPGEKGYSIAGPKGMDGSPGRDGYSGQKGEKGFPGPRGIPGDAKDGIPGPRGPIGPKGLPGRDGLSGRPGIPGSEGQKGDPGGACSDCRPGEPGLKGERGTPGNPGLPGPQGPPGERGYSGERGDDGLPGISGPPGNDGLPGLAGAPGQRGDKGDAAVAPVIEGPIGPKGDRGDPGPSGYPGPPGPEGQKGYPGFVGLAGSKGDKGDRGQPGLDGIPGSSGIPGMKGDKGESVKGERGYPGRDGERGYKGDPGPKGPKGLPGSCPAAEFLTKGPPGPPGLAGQPGDKGDTGPPGLSGLQGRPGERGLKGETGPPGPVGPRGLPGPRGDKGDMGPLGFPGEPGDPGRSGLPGRPGDRGGKGDPGFPGIGPPGPMGPRGDKGESGLIGLPGRPGSLGLSGPPGFPGEKGDKGDIGLDGLRGSKGDPGPGGPPGIPGSPGIQGPAGFDGPKGERGLPGESGPSGLPGFPGPKGDLGQGGYDGPKGFTGPRGLPGPPGQPGMDGLPGQRGEKGDRGFEGPPGFPGGKGDSGLPGLSGEKGDRGQPGLSGITGPPGVPGLKGERGPAGLLGQKGEAGRASEKGQRGEIGPAGLRGPPGPPGLDGMPGDKGDVGIPGFGPPGFVGQKGERGLTGPPGTSGLTGLKGNDGLTGFPGLKGERGLSGLPGIPGEPCIDGMPGEKGDRGFPGSSGPFGPKGDKGQSGRDGLPGQKGEGGINGPSGLPGFPGEKGQKGEIGQSVFGQKGLAGQPGLPGLKGEPGLPGLDGLSGMKGDRGLSGNPGLPGTPGFDGPKGETGQRGLPGPSNNQLGEKGLPGPPGPPGRDGYPGQAGLKGDSGFPGLPGPVGPPGEPGLLGGPGEKGDRGFPGPPGMPGQDGRSGPPGFDGPPGLSGEKGERGLQGLPGTASIKGDRGAPGESGIPGLSGMKGERGFDGIPGLPGPPGPKGDRGLEGISGLPGAPGIRGGKGDRGDPGLPGPTGPKGDTGQSGFPGLKGEPGLPGVPGAPGLPGLKGESGRPGTNGLPGSPGQSGLKGDRGFDGQAGLPGPPGFAGAKGSQGESCQEVGDYLSGILLVKHSQSTMVPDCPAGQARLWDGYSLLYIEGNEKAHHQDLGFAGSCIRRFSTMPFLFCDINDVCNYASRNDKSYWLSTNGPIPMMPVSEDAIRQHISRCVVCEAPTNVIAVHSQTIDIPSCPNGWSSLWIGYSFVMYTAAGAEGGGQSLASPGSCLEHFRATPFIECNGARGTCHYYANKYSFWLATIEDRDQFDRPKSETLKSGYLRTRISRCQVCIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHQ2</accession>
    <name>A0A1D2NHQ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Gamma-aminobutyric acid receptor subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_01894</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Postsynaptic cell membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHQ2"/>
    <dbReference type="STRING" id="48709.A0A1D2NHQ2"/>
    <dbReference type="OrthoDB" id="8890589at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034707">
        <property type="term" value="C:chloride channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004890">
        <property type="term" value="F:GABA-A receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19049">
        <property type="entry name" value="LGIC_TM_anion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.390:FF:000067">
        <property type="entry name" value="Glycine receptor subunit alpha-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002289">
        <property type="entry name" value="GABAAb_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01160">
        <property type="entry name" value="GABAARBETA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0868">Chloride</keyword>
    <keyword evidence="11" id="KW-0869">Chloride channel</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0628">Postsynaptic cell membrane</keyword>
    <keyword evidence="20" id="KW-0675">Receptor</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0770">Synapse</keyword>
    <keyword evidence="4 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="19">
        <location>
            <begin position="65"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="178"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="257"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="374"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN04742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="486" mass="54099" checksum="9F983FEA3483A306" modified="2016-11-30" version="1">MSDIRYKWAAGAGSVGMAHDVSLPQFKVYGYRQKAYEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSSLIVVISWVSFWLNRNAAPARVYLGITTVLTMTTLMSSTNKALPKISYVKSIDVYLGTCFVMVFAALLEYATVGYLAKRIQMRKNHFAALQKMALQLQKSCEEHVQKQYYPSTPQTPAPPTPHQQQAASGPAATPPHGNVNAHAGASRTYVPTTPHQQQHAPHPDYHGTGRFVDSSTLRKYTSTNNAQYVSSQGGQGIPNHPGMGSTMSVAPYYSTQQQAGAPPQGQQQNPRNYDHNRDGRYYDAQVYNAANPNQYYAGGQVAPHTQAPYYTQQNTWAQEPSGCSRAAASSGETHNQTLNHHKLHTTNNTNLNHHQAPSKSHPRLEETRSDNSYPSTLTRSAESRLVTLTKIHCKLLNINTDWQVLSSSLPGMFRVFQPAVLDNLPSHFNGERDGRPRDSEFRRLGSDLKIALFLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI00</accession>
    <name>A0A1D2NI00_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Transcriptional coactivator YAP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_02104</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the YAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000040">
        <property type="protein sequence ID" value="ODN04606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI00"/>
    <dbReference type="STRING" id="48709.A0A1D2NI00"/>
    <dbReference type="OMA" id="NQPLNPM"/>
    <dbReference type="OrthoDB" id="2020426at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070161">
        <property type="term" value="C:anchoring junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035329">
        <property type="term" value="P:hippo signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000019">
        <property type="entry name" value="Putative transcriptional coactivator YAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000012">
        <property type="entry name" value="transcriptional coactivator YAP1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053819">
        <property type="entry name" value="TEADIR3_omega_loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051583">
        <property type="entry name" value="YAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17616:SF8">
        <property type="entry name" value="TRANSCRIPTIONAL COACTIVATOR YORKIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17616">
        <property type="entry name" value="YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15238">
        <property type="entry name" value="TEADIR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="8" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WW" evidence="15">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="15">
        <location>
            <begin position="217"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="59"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="321"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN04606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="462" mass="49469" checksum="F450053B1F9B9BBA" modified="2016-11-30" version="1">MAASGNNGPGSGALPSHKSQQIIHMRGDSDSELQALFDSVLQPGIAGRRPNGVPLRLRKLPDSFFKPPSTGSKSPSVSVSHSRENSVDSTLNPMRRSPMTSNGAMGAGGHHRAHSSPATLEQTYSVAQSHVSQASPSLQSGSSGNLSEDPLPPGWEQACTAEGQVYFINHITRSTTWEDPRKAQHQQILAAVGGEPPNTGSNPSLSAMGIAQGMANGPLPEGWEQAITPEGEVYFINHQARTTSWFDPRLPAHLQRPPVLQQQLNAAALAQAAANAAALGNGATAQLLQMPKQQELRLQQLQLERERLKLRQQEIMRQMEQEQARLARQQPARAPPTQMDDGLELDPFLSGSTMGNPSTPSSDFHSRQESADSGLGMGNSYSLPNTPEDFLSTMDDNMDTISENGLGGASLDTGDIPILGSDPVDSTDDLVPSLLPDELSSELLDEMQSIINSKSDNGMTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI15</accession>
    <name>A0A1D2NI15_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinesin-like protein KIF16B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01854</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI15"/>
    <dbReference type="STRING" id="48709.A0A1D2NI15"/>
    <dbReference type="OMA" id="NISHSHP"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="5">
        <location>
            <begin position="3"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="101"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="50188" checksum="7403B80ECF4D93EC" modified="2016-11-30" version="1" fragment="single">MTNIKVALRVRPLSQRETEANYPVVVAVENNSAFITDIRVPERPSADSRQRFRQFDFDHTFWFSNNGILGAASQHQVYTEMGPHLEKAILSGYNACLLAYGQSGTGKTFTMLGSKDEPGIIPRLCQSLWDKLKAKYPATGGKPGFSMEVSFLEIYREKVRDLLNPEKSLKLREHPQLGPHVQGLTRLEVTGEISLLNLLWEGERRRASGTTSSNRRSSRSHAIWTLYLTVHNNISHSHPDDVANNNASTSRRNQSRGSPARIITNQVHLVDLAGSEKADCTTAKSLLAEGADINRSLVALGNVISALAEKAQYIPYRDSALTWLLKDSIGGNASTSIIISKSLLFLLPTCQYEILCKINSRKIISNLLTLYHHIYVILPKAASPSSHCHAQTLNSLRFAQRARLVENTPKINLASATPSYSYGPYGYLSVMSAMELKKDITRLAKIIKTAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIQ7</accession>
    <name>A0A1D2NIQ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongation factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01668</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN04995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIQ7"/>
    <dbReference type="STRING" id="48709.A0A1D2NIQ7"/>
    <dbReference type="OMA" id="ASWNTEN"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03700">
        <property type="entry name" value="EF2_snRNP_like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="17"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="844" mass="94299" checksum="C14F7131B3E120C3" modified="2016-11-30" version="1">MVNFTVDEIRGMMDRKKNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRADEQERCITIKSTAISMYFELEDRDLVFITHPDQRDPTQKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLEQEDLFQTFQRIVENVNVIIATYNDDSGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYADKFKIDVNKLMGRLWGDSFFNATTKKWSKTKDAENKRSFNMYVLDPIYKVFDAIMNYKKETIDTLLVKLKIELRPDDREQEGKKLLKVVMRNWLPAGETLLQMIAIHLPSPVTAQKYRMEMLYEGPLDDEAAVGIKTCNPQGPLMMYISKMVPTSDKGRFYAFGRVFSGIVATGMKARIMGPNYVPGKKDDVAEKAIQRTILMMGRYVEAIEDVPCGNICGLVGVDQFLVKTGTITTFKDAHNLKVMKFSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPMVQCMIEESGEHIVAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESDQTCLSKSPNKHNRLFMKACPMPDGLAEDIDKGDVNPRDDFKIRGRYLADKYDYDITEARKIWCFGPDGTGPNLLMDCTKGVQYLNEIKDSVVAGFQWATKEGVLCEENLRGVRFNIYDVTLHADAIHRGGGQIIPTARRCLYACALTAAPKLMEPVYLCEIQCPENAVGGIYGVLNRRRGVVFEEQQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVFPGDPLDAGSRTYTVVQDIRKRKGMKEGLPDLASYLDKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJJ4</accession>
    <name>A0A1D2NJJ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJJ4"/>
    <dbReference type="OrthoDB" id="10686971at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="915"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="952"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="916"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="963"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1021" mass="114970" checksum="8FA50CC655AC8B8D" modified="2016-11-30" version="1">MTRKHIPIPRNLMLGIKKSKAETATGSLISQNGRRETSRDLEGLEVRSASSMCPSPVQEQCSEEDKSSETSQSQPMAAPRQRIARTISNNLLLRRWSSFPPDNDESGPIQLRNGIGSSSSLLPRTVFEQEMKWVLYSIWNQTLECCLKCENGKLPMEAEQFRELIIEIIDHVTPFPDFYKSLKEFKVICVERTEVVEDSASKVYGTWCCSTTEEAIGDHAEIRPTPLVIGELLSSRLSPLDLLVLLRSNDSNCNSFNEEHPCIIHVSYKDYNKLDRTMPNHIKLDSVSPAVQSEKNEVVHEEYGSYVIEKYLSLHDIPECERIPLECPDGPLAIALLPFNDFMDYESRDDVANPSSSTSTNVRGAVNGETLPTNNNRESTRDNDVMEQEVLAPSPCSDPDEIFEESDEDNGSLVDHVTPKRCGNFSLVDWVKKGNFVPGSLRPKLQKTDKKKCYEYHKLSELGIMLYNSVAEDRKNELIPNMMVKQQCYTYGVVVEVLQEVRHHNSYFFRISDETMESALVRMQSINKTVGPKIHVGQIIRLHRLTVQVEWDVGISENAMVLSTCAHHNYVIFKLIDGSNQFSYDTCAKTITLCDNDKLRVAELQMFKINRLKQSSNGVTLIDSAGQLTSTIKDIESFISANLRKPDSSDHHNLLSQSNVNGICDSDLASPMISQRVSFSECSKNGQSGQCSQELEEMVHDTEESYVTAMESQNNIDETSLSHTGEDILIDQEQPFVSPEVSPHEDTENPSSNESPSLRNFTLFKNLRKTDERLNLLCQIVTLGATSNINVWHLVIKDLECTSPSEEFKRPVPVDSQQGDDFMELNIINFALARSLEARNIVSTLYNDQGTDQFYAIEDVKVKGDEPPYALEVDGKTCMITRYNQLMQYLHLEESFSCSRPLDSEPDVVDTADDTLVQNGTSPISLKQPNQHSTPVSSPIRSGVLVQIDLQEPNSQSSQSSSVYLSAQATPSPTRRQQSVAEVFGENQLQTVVRKLEVWTGRPKGKRKPREHYQPEDSFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJW0</accession>
    <name>A0A1D2NJW0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sentrin-specific protease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJW0"/>
    <dbReference type="STRING" id="48709.A0A1D2NJW0"/>
    <dbReference type="OrthoDB" id="1939479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016929">
        <property type="term" value="F:deSUMOylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060255">
        <property type="term" value="P:regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.395.10:FF:000001">
        <property type="entry name" value="Sentrin-specific protease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF141">
        <property type="entry name" value="GH15225P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="610"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="806" mass="91257" checksum="A3ADED224C95F2FF" modified="2016-11-30" version="1" fragment="single">TLVTRTKDYITALVSPHQETDRNCNNSNSLGEGRGRFASIQKYFHNRGGPSQKRPAASAFEPEITDDEDEELPGAGNSYNFPVPKRPRVDFNGEMSSKRSHLFSPPPSSNSRYVTRGSGKTPELAGLKKQPWDFDFTFGRSRRKIVTQINMREPACESKDSRSVVDIPGPSQGSVVVNNSKNYSYRNSTGSKVVNIPIRMEEDFSFSRTGGLRQVPEVITLDDCDDPPPCSALVPLPPSKNEMERIIRPKISSPIQKASSKARDQNNICRYLSTSIGQKLPGKSSSRSSSNAIRPHEKDQYRKLLQEWGILNVTKRPLFKSKIGQPDLQVMYNRRFQSSPTNGTVTIMSRAKALLEQTDASSSISQRISLPHLFSTPKEPVNFSGRSRASSSVLPPKDAPLVIDLEPDFNCKELVTFQPPVSPISKPEKSSHSTSLNISAVGNFSNLEDALNISALVKSSEDEEEGSFLESSQHDAQDEDLSVIAEKVVNKSRNSTMNTLALEQTSCPYVDKRWLVDSQSSWRENQRHRNNRIREQSGTIDLLRRESTLEKELEDRIRKKLTLTEIIVLEEPPAGLPELDDEMRDIIQRAKARGNDNDVLAQVRLLKDTISITRGDIRTLGPSQWLNDNVINTYMGLIVLRSKTTDNLPKVYAFQTFFYPKLLKEGYSNSLKRWTRKDDIFAHDLIVLPIHLGLHWCLACVDFKSKSILYFDSLGGDNNKCLHSLMDYISKEMRERKQMELNKDEWTLTNVKGIPQQQNGSDCGMFACKFAEYLSREAKFTFTQENMPYYRDRMIYELLKQDLMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJW1</accession>
    <name>A0A1D2NJW1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trypsin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJW1"/>
    <dbReference type="STRING" id="48709.A0A1D2NJW1"/>
    <dbReference type="OMA" id="MEWILEQ"/>
    <dbReference type="OrthoDB" id="60866at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905669" evidence="2">
        <location>
            <begin position="23"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="24"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="28382" checksum="C5ED99D2662F6F90" modified="2016-11-30" version="1">MARLNYIAVVLLLISIPSVIIAKIAGGAPASAGEFPFQVSLRNSGFGHICGGAIISPSLVVTAAACTDPRSPSIDEVVAGSLKRTENVTWQQVRSIERFVVHPGYNGTTLDNDLSLLFLSEPYEFNENISSIQLPSAYIETAPKPVVLSGWGSTQYGEPMFEDLMKVTLDTYTDSVCEEWVEQYVRPEILCSGADDGGRGGCQGDAGSPLITQGNNSYVAAVLSHFPCPRPDCCGIVGPNDQSTELSFYMEWILEQSRMYGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKX1</accession>
    <name>A0A1D2NKX1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Exosome complex component CSL4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00769</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKX1"/>
    <dbReference type="STRING" id="48709.A0A1D2NKX1"/>
    <dbReference type="OMA" id="RCLITHV"/>
    <dbReference type="OrthoDB" id="440760at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039771">
        <property type="entry name" value="Csl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE CSL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exosome complex component N-terminal" evidence="4">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="28491" checksum="3CC4C2AF54D59E68" modified="2016-11-30" version="1">MPKDSQSTTEEEEYEYDPEEGVPVPKRLLYSDDKQKFKPKIATGTPCMPGQRICIANEYFEAGEGAYEFGDSIYASTLGFLQTEEFAEQELTVVSIKRGDGKPPFTAPYVGAVVTCIVLSRTQKLCRCLITHVGSIKLDDVVKGIIRREYIHEKHRDLSEVETSFGVGDTVLARIVGISDGDFIMATGEDSLGVATAISSAGYYMVPVGWTRMECPKTKETLPKKVAKIVQDKNVEYWHQRNLNSKKESDAKTEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL30</accession>
    <name>A0A1D2NL30_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Aldehyde oxidase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_00856</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="13">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000015">
        <property type="protein sequence ID" value="ODN05815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL30"/>
    <dbReference type="STRING" id="48709.A0A1D2NL30"/>
    <dbReference type="OMA" id="CRPKSIQ"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000012">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908:SF132">
        <property type="entry name" value="ALDEHYDE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 13" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="14">
        <location>
            <begin position="9"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="15">
        <location>
            <begin position="215"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="699"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="810"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="927"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN05815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1084" mass="117650" checksum="B23CE7CD17C5BD09" modified="2016-11-30" version="1">MVKGDSSGSTVVFHINGQKHSVDANSNIGPTTALVDYIRDVANLKGTKVMCREGGCGACTVTAKVIDPATGAEIQKSVNACLTPVLSCDGWDISTVESLGNKQEGYHVIQNRLVNFHGTQCGYCTPGMVMNMHALLGAKKDLQMEDIEKNLDGNICRCTGYRPILDAFKSLAKDASIELQQKCSDIEDCATCPMKKANGASCSGKAKVSTSNSLKLPSGEEWVVAKNLENALITAHQSKSNGADYRFVAGNTSTGIFKNQGPYKTFIDINGIPELKKTSVDKNGIVLGGGTTLTETINLLRESAKLPGFEYGKRASTHLERVANVSVRNITRRYQNAHAYVNAGFLFKVNKGTGVTVAEKPRIVYGGVSAAFIHATAAELSLQGKDLTDEKTLRDALQALEKEVRPDVGPLESSPFYRIQLAKTLLYKTILEIIGEKAAQKFRSGSSDLERIITKGKQTYDASQAETNLYKSVPKYEGTIQASGEAEYTADIPFQTNELFGAFVLSTVPNGNIKNMDASAALKIPGVERFVTAKDIPGINDVMKFHFFPNTTPEPVFADDKVSNHGQALGLILATSKDVAVKAAKLVNVTYENVTKPVVNIDDAVAKAKEDGSLQKQTMGTFSLPPPEDVKVANTLKGTLKFGSQYHFFMETISVVCHPREDGIDIYCLDGNGSNAVALVLNIPTNSINVQVRRLGGGFGGKATRPNFVGSRLRSRDLGYRSTMSNCFRFRDKYEHVRKTPSLSHPLRRFDENGKIGSLKSDLICDPGSSANESSAITALVHIQNCYKAAGWEVSPRFVYTNTPSNTPCRAPGSVQAVAAIEWIMDHIANHLKKDPLEVRKANFLANGDKLLFTFLEGQPTYDRENLIPDMIENMKATADYEARLAFIETFNKVIQTVAQVLQIPMDRIKIKASNNFVAANALVTGGSTGSELTCYSAIKACEELRENLRPILEKLEDPSWDKLIQAAAAAKVKLTASYTPTAKDDIKGYDVWVLNATEVEIDVLTGEYKIIRTDLYEDVGRSLSPATGEPSTDAAFSVVLAMRNAIAAARADAGNTDWFEMSGPVSPEDIAMLCLTKTTDLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL77</accession>
    <name>A0A1D2NL77_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-transporting two-sector ATPase</fullName>
            <ecNumber evidence="2">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_00694</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits VhaAC45 and ATP6AP2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL77"/>
    <dbReference type="STRING" id="48709.A0A1D2NL77"/>
    <dbReference type="OMA" id="RIVKTFW"/>
    <dbReference type="OrthoDB" id="1676488at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18111">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18119">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01134">
        <property type="entry name" value="V_A-ATPase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000008">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000052">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00309">
        <property type="entry name" value="ATP_synth_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005725">
        <property type="entry name" value="ATPase_V1-cplx_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003220">
        <property type="entry name" value="PRK04192.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01042">
        <property type="entry name" value="V-ATPase_V1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607:SF1">
        <property type="entry name" value="H(+)-TRANSPORTING TWO-SECTOR ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="13">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="ATPsynthase alpha/beta subunit barrel-sandwich" evidence="14">
        <location>
            <begin position="121"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="12">
        <location>
            <begin position="227"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="15">
        <location>
            <begin position="460"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN05969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="613" mass="68140" checksum="A97A0EE1E8B2DC49" modified="2016-11-30" version="1">MSQPKVRDEEKESVYGYVFAVSGPVVTASHMAGAAMYELVRVGYDELVGEIIRLEGDLATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMSSIFDGIQRPLQDICEMSKSIYIPKGVNVPALSRTKKWDFVPDRNIRPGSHVTGGDVYGMVHENRLVKHKLMVPPKARGTVTYIAESGNYDVKDIVLETEFDGEKSKFSMLQVWPVRQPRPVTEKMPANHPLLTGQRVLDTLFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELNVEIDGVTESIMSRTSLVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVRCLGNPDREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDYYDKNFPEFVPLRTKTKEILQEEEDLAEIVQLVGKASLAETDKITLEVARLLKEDFLQQNGYTPYDRFCPFYKSVGMLRNMIGFYEMARHAVESTAQSDNKVTWATIREAMGNTLYQLSSMKFKDPAEGEQKLKAEFDQLYDDMSVAFRNLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM04</accession>
    <name>A0A1D2NM04_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine protease 55</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM04"/>
    <dbReference type="STRING" id="48709.A0A1D2NM04"/>
    <dbReference type="OrthoDB" id="8189841at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF54">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905726" evidence="5">
        <location>
            <begin position="20"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="68"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN06125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="306" mass="33806" checksum="1FEDF0B75F697FAD" modified="2016-11-30" version="1">MIISSDYCLLLIFGWLCHAEGLAISTKGRKLFHTSAWNKVVKSAHQCGRAFIRSESQNAAASERAARIVGGFKVDSPIPWQVSLQREVSPGIYSHICGGVLISAYHFLTAAHCISPKDRYRVVLGKHKLHSSSSHEQAFDIRQSDIVVHRRFGEIAEYANDIAILKIERANGEGAKLNELIHPICLPESADWEMMVRDSPFSECIVSGFGSINGSDLNTPSNSLRAATVPIHNQNTCDKLYNHEYFDSRGDYGFIESNRLRSIKVTKNSRRSFGGGVYFVNDMLCAGPLSGSKDHCFGDSGGTFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM71</accession>
    <name>A0A1D2NM71_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosolic Fe-S cluster assembly factor NUBP1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00282</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="8">Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM71"/>
    <dbReference type="STRING" id="48709.A0A1D2NM71"/>
    <dbReference type="OMA" id="VSGCPMR"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001119">
        <property type="entry name" value="Iron-sulfur cluster carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF35">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN06378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="305" mass="32380" checksum="5A72BB4DAF073B99" modified="2016-11-30" version="1">MEDVPEHCPGTQSEKAGKESACQGCPNQKICSSGEASLPDPAISVIAAKLSGVKKKYLVLSGKGGVGKSTVSTLLSRAFATKNELNVGLLDVDICGPSVPRIMGCEGEIVHQSGSGWSPVYVDDNLCVMSVGFLLDSPKSAVIWRGPRKNALIKQFLTEVDWGTNLDILVIDTPPGTSDEHLSIATYLSKASVDGAILVTTPQDVSILDVRKEIDFCKKTKIPIIGIVENMSVFVCPKCKVASELFPKTSGGGEALAKEFEIPFLGRIPIDPNLASTCDEGTNFITGFPDSATTQFMTDLASKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M129</accession>
    <name>A0A1D2M129_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glutamyl aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_20015</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007748">
        <property type="protein sequence ID" value="ODM86667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M129"/>
    <dbReference type="STRING" id="48709.A0A1D2M129"/>
    <dbReference type="OMA" id="NIPYQWL"/>
    <dbReference type="OrthoDB" id="510539at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="13">
        <location>
            <begin position="8"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="11">
        <location>
            <begin position="174"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="12">
        <location>
            <begin position="439"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM86667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="603" mass="68603" checksum="AD0BEE9A39C4624E" modified="2016-11-30" version="1" fragment="single">KFPTSGENLYTISLEESFQLGDQMQIFIPYEVAISDDNQVGLFKRGYAVEASNQTEIRFLSATKLWPYHAKSVFPCFDDPSLKATFKIIIGRLDGQYRSLSNMEIAKTELDMDHEGWVWDHYEETVKMSPYLVCMIVSDFHNDTIQINNGTRSVSTWAPKHDIEQGRTSFGTRTVAKTLQYYEKKFKMNFPLRKLDAAVVPLFSSSASENFGLVTYRQDNFIWGPGTNTEGARRKVAQVIAHETVHQWFGNVVTCASWEDVWLNEGFARYLQFWAMNETIPEFEPTQAFVNDVTQLTMKLDQKSSGYTLKIPGRYAGSLVYGKGASMLKMMEGFLTIDVLEAGIVDVYLQKMKWKSVTPEDFFEAIQETVEMHNKTHLLPPETTIKDIMLGWTITSRSWWIPIKIVSGNDLSNTENIWLPKNVSTLNYTSSNIDTTKLLMVNPDATGYYRVLYDEKLLSLIAKQLLDNHTVISSSSRSQLLDDYFTLAFANYTSIETALELTSYLEKESSSNVWTAILHHLNPILNIFTQNKGALEAFKNYFLPRLEGALTIIGVRQLEGQRGINVTLRAQLLKMACQLGMPACVEYANELMSHLEADPQVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M141</accession>
    <name>A0A1D2M141_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CD63 antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19993</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007629">
        <property type="protein sequence ID" value="ODM86689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M141"/>
    <dbReference type="OrthoDB" id="432835at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM86689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="12940" checksum="992F2E9DC3F83611" modified="2016-11-30" version="1" fragment="single">KCCGLAGHSDWADASGAPTVGFIPDSCCLNRFQRAGTCARKITRGNMDDHYFVSKFIYTEGCLNEFDYYYSVDGLGHFAIAMAVFQLFGILLAAGFLWKGSEENGYQNLDENHDDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1P3</accession>
    <name>A0A1D2M1P3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-conjugating enzyme E2 Q2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006955">
        <property type="protein sequence ID" value="ODM86862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1P3"/>
    <dbReference type="STRING" id="48709.A0A1D2M1P3"/>
    <dbReference type="OMA" id="TGPITHE"/>
    <dbReference type="OrthoDB" id="109543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23802">
        <property type="entry name" value="UBCc_UBE2Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="204"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="42278" checksum="B20DAD03648086FF" modified="2016-11-30" version="1">MFNEIRAVEAVFPKTHERFQVVSTTLDELVCSFICKNGKKHEVTANITQSYPDDPPIWFADTEDSSITEAVLTLSSTSGMDNHVINQVGMLVRALYNTQDLPEPTPELEKLRKMSPAVAATPKSPGWRPSASGADAAEMEIDYGFFKEEDYWEEDDIDLDFDKSPDKDKEKEGLDAEHLKMLDRIQARRRDEFSERAGGSGSIQASERLMKELRDVFRSDTFKNEVYTVDLVDDNLYQWKIKLKGVDKDSQLYADLLTLKAKEGKDFIELDMHFKENFPFEPPFVRVVHPVINGGYVMSGGSICMELLTKNGWSSAYAVESVIMQIAATLVKGKARIYFGENRQYTLARAQQSHKAVTQIHEASGWHTPPKSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Y1</accession>
    <name>A0A1D2M1Y1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Speckle-type POZ protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006598">
        <property type="protein sequence ID" value="ODM86966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Y1"/>
    <dbReference type="STRING" id="48709.A0A1D2M1Y1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10400" checksum="D474FC1CF20B9C09" modified="2016-11-30" version="1">MDELAPELLKIAEKYELSGLKADCVYELGDKLNLENAGELLVLAQTHNAPDLKTRAMDFINLNKDKLLKSKSFQDAVKLADAETLAELYFSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M207</accession>
    <name>A0A1D2M207_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006503">
        <property type="protein sequence ID" value="ODM86999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M207"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="99" mass="11325" checksum="BA6A39072F027E5B" modified="2016-11-30" version="1">MSDSEVSSEAAVIEKSFQCKQCKDGRVFTAEQKDEHRAWHKAQREREARKRPSRTRMSPVPSEVTLFESTASPSPPARKKRRSVKTYDTGVKPQRFSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2H2</accession>
    <name>A0A1D2M2H2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_19521</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006020">
        <property type="protein sequence ID" value="ODM87160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2H2"/>
    <dbReference type="STRING" id="48709.A0A1D2M2H2"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08161">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="12">
        <location>
            <begin position="91"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM87160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="451" mass="51986" checksum="DBD0444D2B22F4B0" modified="2016-11-30" version="1">MKCVWNDSAKCNLLTLLRVAARKYNEGYFKRDGVIQTKHCCVNDSPGKCTSTECMNAGSRIICSPKTIDSGNAIKMNENCTVWPWEFNDWPWLLIYDTQIPDLGDGVKTLKDIPKGKRVMFYVGEITLMKDLQELPSKYGMKISNCGEGHLVINSKKYGGIARYCNHSGKKVANLKIERYEWETWPLYVLSASRKIKAGEQLTYFYNNCHIMKEKRFRKHKIEARIKLSRKCKSKAISNQNHFEDQTCQSVTERKQPHSNQIAEHAHDPILNACDETTNGNQELQLVPFVESRTGSSNPIVSSRNTIRAQLPKLMPAPSQTDLENIRQLEKIPPPPKLQAIPQGNCVTPPKLCTKQFKCPECDKSYSRKDAMLRHLKSIHEDPVVYLCKVCSVNYNLKSNLKQHMKRKHNSVTSDEKQRPFKCDECSKQFTMKKNLYQHCRKFHKEIHLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2V6</accession>
    <name>A0A1D2M2V6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta/gamma-crystallin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005629">
        <property type="protein sequence ID" value="ODM87300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2V6"/>
    <dbReference type="STRING" id="48709.A0A1D2M2V6"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001064">
        <property type="entry name" value="Beta/gamma_crystallin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00247">
        <property type="entry name" value="XTALbg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903411" evidence="3">
        <location>
            <begin position="22"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Beta/gamma crystallin 'Greek key'" evidence="5">
        <location>
            <begin position="23"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="4">
        <location>
            <begin position="116"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Beta/gamma crystallin 'Greek key'" evidence="5">
        <location>
            <begin position="264"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="352" mass="39806" checksum="28431622AE40F78D" modified="2016-11-30" version="1">MKQKDIIVLFLVALHLVENNAEQVILYEDSNFKGDYITLTLSGNECVTLPEYWYDRASSINTQNNCVIAWSYSSCVSGSSERIAPGTPLHSQLSGIELDDQIRSVQLCSGPAQETGGRWAGVRSHYYHRISHSASELDGGNEELHQAARRHAEYLAENNILVASSTSQNVGEAEGNREEEAVRKVIRSWYREERHYDYKQPGFREETRHYSALVWKSTTEVGIGVAWNPIKKVYVVVANYNPVGNRNGEFNQNVVPQQRFAEFPVVFYEHHNFEGESIKMELIGGCHNFPEGWHDRATSVNADYKCIVAWEHYGCVGKSVRIKNQKISNLGDLGFNDVMSSFNLCSTLSENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3Y9</accession>
    <name>A0A1D2M3Y9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Larval cuticle protein A2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004826">
        <property type="protein sequence ID" value="ODM87698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3Y9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="121" mass="12638" checksum="1580CA5E5F350ED2" modified="2016-11-30" version="1">MEEAIASYGVLGWLNMDPPMVPMAHQLLEPICSGQAPVAHAVAAPVIRAGLTVTYTSDPVNGFNAVVDRQRPQVAVQKVAAPVAFAQRPIAVAQPAVTAVHAGAPYGYAQQAIAGPGYYHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M411</accession>
    <name>A0A1D2M411_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004804">
        <property type="protein sequence ID" value="ODM87717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M411"/>
    <dbReference type="STRING" id="48709.A0A1D2M411"/>
    <dbReference type="OMA" id="VISPICQ"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="306"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="393"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM87717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="432" mass="49079" checksum="CBBD9F8C0F89037D" modified="2016-11-30" version="1">MMGTCDLPIPIFTKFLKVAQEYLKVSSVATKRLLRVIGDGKDGVFCGNCEVTVISPICQVYSQLLCARASLSVELEKLQVVLEDSTESSLDKVKLESTPSLVVHNAKLSYFKPFRSSLSEKCQQKRSEFLPRVIVQRLIVTPTAPGVTPKKEPDVFDDFQDELDDADTFEPFDDDDDLHHSPRDSFAEASREDGPTDLNGEEFLLKREVIQEPELAIKIENVEQRDDSTLEPVLKKPRRKGRKLLTKPNRLKCSSCSKLLLNEEQLKLHNRNYHEPTNCSSCGQTFSGESLFNRHWARVHSTKGKIPCPSCPKVFRKLDSLTRHRKYAHGGDSESFPCPTCSRVFPTALRLLCHRNAHSSRVYPCDHCAMSFKSRTPLLYHLSLFHKSVATVFPCPHCIIVFKHEQNLKSHVRKRHSLTSPKPVVKRESESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4B6</accession>
    <name>A0A1D2M4B6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_18864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004641">
        <property type="protein sequence ID" value="ODM87817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4B6"/>
    <dbReference type="STRING" id="48709.A0A1D2M4B6"/>
    <dbReference type="OMA" id="DAPCRVN"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF41">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811313" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="32"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="571" mass="65812" checksum="E8DDB579B5D1987A" modified="2016-11-30" version="1">MELRFIIVRNMGFRRLTLYFVLLISVGKLHCDEHTHTYKDNEEVVLWMNTVGPYHNRQETYSYYSLPYCQGPKEVIGHYHETLGEALQGFELEYSGLSIDFKSDTPPTVFCEIELNEEKLKAFVYAVKNRYWYQMFVDDLPIWGVVGEPDDTKGEYYVYSHKKFDLAFNGNQIVDVNMTTEGKVLLTVGAKIPFSYEVHWKSSKTKFENRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYAKDEEMDDMDRDLGDEYGWKQVHGDVFRPAAKPLLFSALLGTGCQLLVVTVAVILFTILGELYTERGSLLSTAIFVYAATSPINGYFGASIYAQMGGKRWIRQMLCSVALLPAVVCGTSFFINFIAIYYHASRAIPFGSMVAVACIVLFVVLPLTLVGTVLGRNLAGQADYPCRVNAVPRPIPEKKWYMEPAIIVSLGGVLPFGSIFIEMYFIFTSFWAYKIYYVYGFMLLVFLILLVVTICVTIVCTYFLLNAEDYRWQWTSFFAAASTSGYVYLYSIYYFIFKTNGWLWNTVSKLPFLFFGKLHGPLFALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4M1</accession>
    <name>A0A1D2M4M1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Selenide, water dikinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_18759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004401">
        <property type="protein sequence ID" value="ODM87923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4M1"/>
    <dbReference type="STRING" id="48709.A0A1D2M4M1"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256:SF0">
        <property type="entry name" value="INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="SELENIDE, WATER DIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PurM-like C-terminal" evidence="3">
        <location>
            <begin position="56"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM87923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="24338" checksum="08B12AB667A6E878" modified="2016-11-30" version="1">MSVIPLICRASRDTASEAGTEVTGGQTVINPWITIGGVATSVCQPSDIIMPENAVVGDMLVLTKPLGTQIAVNAHQWLEMPERWDRIKHVVTEEEVRKAYNRAMDSMARLNRTAAILMHKYNAHAATDVTGFGILGHAQNLLRINDQKSPFKHEWGCKSLWKYVPASCRFFCRDVRWSADLFSSGSSSSFYQRDLKDWKDIKHGVGDSREGKPNGKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Z1</accession>
    <name>A0A1D2M4Z1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004182">
        <property type="protein sequence ID" value="ODM88050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Z1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903473" description="C-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18574" checksum="95F66F629635D1D8" modified="2016-11-30" version="1">MGKLAPFLIVLAALVYSAAAISSKSLVGQVITIDRFDYFSDRSSTLFLNKKRTQEAARLYCESYYGKLAPVLSFKAYVRLLDKIVNGVYWIDGYESNDVNRFSFYNNCTSDTENINMGNANLVVGGKNCLVLVKPTPTQQHRIEPVPCSTTRARVLCARENSVCPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5S2</accession>
    <name>A0A1D2M5S2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Macrophage metalloelastase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18363</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="7">Can bind about 5 Ca(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M10A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003770">
        <property type="protein sequence ID" value="ODM88319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5S2"/>
    <dbReference type="STRING" id="48709.A0A1D2M5S2"/>
    <dbReference type="OrthoDB" id="406838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030574">
        <property type="term" value="P:collagen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04278">
        <property type="entry name" value="ZnMc_MMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033739">
        <property type="entry name" value="M10A_MMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201">
        <property type="entry name" value="MATRIX METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201:SF310">
        <property type="entry name" value="MMP-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="8">
        <location>
            <begin position="115"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM88319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="312" mass="35571" checksum="05EC4AA7E7F2DF14" modified="2016-11-30" version="1">MNIPVLSDDSSRKESCTSYFNMWHPRLPFFWVTLQLWIDYGTPVSITLENDSNFFERNGDTFVENETGAITGIVEPNVARQTDRGALKIQHSLRPVFLEKLESSEIGENVTYCWVRSRWGMQHLSYTISKYPRRTQLLGGKKRVDEVFERAFGIWENASALTFIRTTTRWPDIDIPFDSGWHNWFCKPFDGQNGVLAHASSPRHGAHIHFDDDEIWTVDSYDGINLLQVAVHEAGHAIGIDHSEVAASAMAPRYRSYNPNFELDADDVEAVRALYEKMLPSTDDSQEDALPIIITVVVGCLFNGFADYWANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M601</accession>
    <name>A0A1D2M601_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative treble-clef zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003642">
        <property type="protein sequence ID" value="ODM88396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M601"/>
    <dbReference type="OrthoDB" id="6506929at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026049">
        <property type="entry name" value="C2orf42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029269">
        <property type="entry name" value="Zf-tcix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13518:SF1">
        <property type="entry name" value="C2ORF42 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13518">
        <property type="entry name" value="PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14952">
        <property type="entry name" value="zf-tcix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative treble-clef zinc-finger" evidence="1">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="143" mass="16644" checksum="D6156AA42DFFCCBB" modified="2016-11-30" version="1" fragment="single">MERPFRWFRKTYETWIRKCPKCGTVNGTRGNSCKNKACDVVFRNNGASKKTSTEACKLTLNIPGLQIFSVRLRDRGPDYRNFVQLPLSPVSDEKQEANPYSQCYVDTCRRNKVVSLHPLSVMLIMLMLNEVLKETNDRCNWYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7C4</accession>
    <name>A0A1D2M7C4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal ATPase PEX6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peroxin-6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_17824</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003110">
        <property type="protein sequence ID" value="ODM88859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7C4"/>
    <dbReference type="STRING" id="48709.A0A1D2M7C4"/>
    <dbReference type="OrthoDB" id="2187at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19527">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000109">
        <property type="entry name" value="Peroxisomal biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047533">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF9">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="327"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="612"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="811"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="811"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="869" mass="95865" checksum="9E3ADD709DA3137A" modified="2016-11-30" version="1">MDRAAKSRLKSSASSKVHEAQRIQFLLNVCLRQAPIQMKYTVQRTFALVSYVLLRQRQLTNIKFSNECDSSLVSVESGTEATFTEEDAKNIDPARVIWVEGDTLNKYLIRAGQWVKVCKFSEASNEEAFFICQVLPLPQAEDSATMIKLNPVSEYNLRRALNISPFTPIPHLQVRPLVTDPVIKTHNKSLSFAPIQGKSVKLTRLKCASEISSMDWDLLIQDAFVLHCKYLCVGDLISIPLSDTTSLDLVVSEINSKKVEDDCKEVFKVTHASSSVFINSNEIHDQFHPRIDDFHVEGLVPPCLINIFNRMCDEMKQALAAKNSPDLWPNFLLYGNIGTGKLTVCKTVAKYLGLNFHYLNGINFIGDTSAYSEAKLRATFDKVKNSLCPALLFIKNLHLIGKDKEGHEDKRVVIAFKEFLRDLASVSTSSTSSGPTNVMKSAAIFVVGSTDSPDALVPAVSHNFLFKMEFSATISSVTDVESTLRWLFNGTLEKGINLGAWVKENCVGMQRSFGDFKALAACARRESFTRQSSTCNKDCDTGSVNGKLEVNLNDLNVGLLNVDGILKKAASTVEVPKVSWEDIGGMEEIKSELINSVRLPFEFPKLFSSGIRRSGILLYGPPGTGKTLIAKAVATEFKLSFLSVKGPELLNMYVGQSEQNVRDIFSKARNAAPCIIFFDELDALAPNRGRAGDSGGVMDRVVSQILAELDGSHSTPDVFVIGATNRPDLIDPALLRPGRFDKLLYVGINKDVHSKCSVLKALTRKFVMSENVDLMQIASFLPNGMSGADLYSLCSDAYMIAMERHILKLSNDPSGNSDAPTEQDNKSEQPKAVTVTVSSQDFQTALLRATTSLSEAEQAKYDALKTMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8E4</accession>
    <name>A0A1D2M8E4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002813">
        <property type="protein sequence ID" value="ODM89202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8E4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29379" checksum="E793D2AFB9961CCF" modified="2016-11-30" version="1">MGGGIAYKAFEPISENERCVWTIRAGIVKGFTLNVLNIGISNSTTDTQVIASCLRHQAGPTYFLLNQTGSVNGVGGCDVLVITLASGRDVGNSSGFVLEYSVLRNSTLSLESQDYIIKAEEAAIIRYPSPALEYTNFEFTTFTILPNLGSKTNVIYFRNSLEGTTCLDNLRIYRFNASSEVPTKWQYDGIICGQIPSNVIINDDLILITFNSDISRVGSGFELAVVTSAASECHMFRNLFKFIDNAVRKFSHFIFGRQIDSNSQKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9G9</accession>
    <name>A0A1D2M9G9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dolichyl-phosphate beta-glucosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002491">
        <property type="protein sequence ID" value="ODM89625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9G9"/>
    <dbReference type="STRING" id="48709.A0A1D2M9G9"/>
    <dbReference type="OrthoDB" id="3784at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903661" evidence="1">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="137" mass="15117" checksum="009DC61185C23A1B" modified="2016-11-30" version="1">MGLQSGVFLVLCVDLGSYGGGFNCVTILFSNCVDVCIPFFGVAVHRAWNSDTQCGFKMFTRSAARIVFHNLNIERWAFDVELLYIAQKLKMPIDEVAVYWTEIEGSKVTSNSELDSNGDGLVCNLASLHNRALETGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9K7</accession>
    <name>A0A1D2M9K7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002475">
        <property type="protein sequence ID" value="ODM89658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9K7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="49" mass="5556" checksum="B515C4D84D64CB58" modified="2016-11-30" version="1" fragment="single">MAGNEPPVAPRPRGTHPTVREIHKNAWLKRQIPGDKKGTRFLKRVRNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9S2</accession>
    <name>A0A1D2M9S2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002425">
        <property type="protein sequence ID" value="ODM89720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9S2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="134" mass="15260" checksum="97AB3D324FEAC26E" modified="2016-11-30" version="1" fragment="single">CWKKQKEDKGSATLFVANQEKFEVHRENFVPVDDISKLIDEALKCSKRRTCIELSLKYDCKNETFQPLLNFILDKTFVRKLNQGLPSSPTIGVEGEAEFCKNGMTLSSANTTVAFSISGELEIIQILYFLLQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA51</accession>
    <name>A0A1D2MA51_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16816</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002314">
        <property type="protein sequence ID" value="ODM89866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA51"/>
    <dbReference type="STRING" id="48709.A0A1D2MA51"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="92"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="244"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="410"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="518"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="652"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="7">
        <location>
            <begin position="990"/>
            <end position="1123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1134" mass="125638" checksum="28560F8203DB1034" modified="2016-11-30" version="1">MQNKIVHKMGVVDAVKVILRALPGRWPLPIPVSVFSATFLTLAINSWVAYDMSRDVKTNNELRTKDTKCQFTTFDYIIVGVIYNSGGAGMVVATRIANASSSNRILLLEAGGEPSVLNDIPKSYDHKGKMLGGSTATNFMMYVRGNKEDFNRWSTEDLGGDPQWNYENLLPYFKKSEDYNGAWANEPDAFKYHGKGGLRNVAKCDYHPGAEELFAAALEKGYSQGITMGQIRVKFQTCLESQKLGVVYKRQGLTRIATARKEVILSAGTFESAKILMLSGVGPAEHLRSLNISVVKDLPVGQNLQDHLITLVGPFLKAPAVNPNRDVTAQAAYHYLSTGNGILAASDALAGQDRIMQISSDTRCLCPLPHLPEDMNKMFGVRVDILKKWFDPYHKNDTDARFRLLVLGRPKSFGNLTLASRNPDDNPIMDPQFLTHPDDVEAMLYGFKKFVDLYENTTALNTPLFHKPVPGCEAKEFRMCHSHVLVHTLSSCWDLRFGKGGGWQLEMIEFIFSLLFGHVRVIGIDGLRVIDASVIPREPNANTQAATIMIAEKGSDLIIADITSQCVHELQLLATLHLVKTFETCRMGVVDAVNTILRALPARWPIPIPISIFTATFISLAINSWVSYDISQDATVNSEILTLDSKCQFTTFDYIIVGGGGAGMVVATRIANASSSNRILLLEAGGEPSVLNDIPGLDGFLSNQPANTWFYNSTVQANACQNCDGKVNNDNARKNVGCSTSTNFMMYVRGNKEDFNRWSTEDLGGDPQWNYENLLPILKNLRIIMEFMQATLPQRNTMEKEVFAMWQPMIFSQVLMNFWLLLWKRGIQSGLQWGKSRRDTGKPSNLCIKNMLMSPKSLSNCFRSAKSYFSNVQTPRSHSNSDCNQRNHPQRWGYILTFGSAKLLMLSGVGPAEHLGSLNAAVSYLSTGNGVLAASEALAVIQASFGLYPQLPQDLNRMVGIRADILDNWFDPYHKTNTDARFCLLIAGRPKSFGNMTLASTNPDDNPIQDPQYLANPDDVEAMLFGFKKIVDLYENTAALNTSLFLKPVPGCESLVFKSDDYYRCVIRMFSFTIYHHVGSCSLGKVVDSQLKVKGIDGLRVIDASVMPRLPNGNTQAATIMIAEKGSDLIIADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAT7</accession>
    <name>A0A1D2MAT7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose 1,6-bisphosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002230">
        <property type="protein sequence ID" value="ODM90022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAT7"/>
    <dbReference type="OMA" id="CAVYFNI"/>
    <dbReference type="OrthoDB" id="8268880at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="483" mass="56255" checksum="282560916542A825" modified="2016-11-30" version="1">MELQERSEMQTGGTLKKRKRRAIAKVTGLGTVPYDENDDNFDARTIFSDKSPNDQPNHFKINTGPDTRIRMSYLHELGDHQLTKSGKRATRDPAFHLEEGENEEDEDEQARPPNIPTYIPMKTREEYIKDRPYFLDKTTMTRLKQILILGMFSGTFPWKWNSKTHRIDKWSPTFEKLWNFQWFFVTIQTALLTGFQFYSFISRLETDIKTYREVFMNSVSVYWYVCAVYFNINMYTYKDQCLFTDKYLLHLDDYDDGGRIVINLSIPSNTSQVFASVALFLVIPYQPWYLFSYIYPKPWYCLIPGAIQEFVVVGQVIIAVLHNHNDSGYTREELRNPKTAVETYRTLQILCTCFNDCMSPLAIPLMKTHILTGLIPCGYVFIRSMNHKFIEEFPGILTYPICVIDCATAGFTTLSLAAEVFDLACGFVDSWSRTRQKDFRRILMSCPVLKVKVGRFYYVTVSTTITFFKVATDYIIDCIITFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAU6</accession>
    <name>A0A1D2MAU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002249">
        <property type="protein sequence ID" value="ODM89994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAU6"/>
    <dbReference type="OrthoDB" id="6366701at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903730" evidence="1">
        <location>
            <begin position="24"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="286" mass="32091" checksum="6625756771686972" modified="2016-11-30" version="1">MKSAIIFFVAVLYSLTFPMFVIGEPYTITDCGHDFYPYEEGVIKNNGVALPSNKRCVWTIRSRDTASYNLYYDIGSNSRDIGFTATCISSIGSSNVTVSNFRLSGIGVEKSLPDNCPVLVITLYSEANPLIVGNNGRYYLRWEARRGTALHYSYDSEHEVEVVSGSGIIKHPVVEGRTSYSNNELSTFIFLPEGNTYSNSAKSVVTYIQDVNGMEGSCCDYLTTYKFVPAEGYKSYFFWSDYDKMCASVTTAYRKSSDTLMFVFRSDGSVVRSGFRLLYFNVKCNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBY6</accession>
    <name>A0A1D2MBY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001942">
        <property type="protein sequence ID" value="ODM90483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBY6"/>
    <dbReference type="OMA" id="AVSIRWF"/>
    <dbReference type="OrthoDB" id="10070859at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="445" mass="47487" checksum="5E6D5591BF1BC296" modified="2016-11-30" version="1">MRAHRGVPYASEEEPKTCCGMSASQAVSIRWFIIVIAVIGICCTLAGTALGAARSAGKEHLTLSLLMIGVGVLLLTVSAVAWRLTANESGTSCRAMLGFARAGSSRGDGGSEPNRRFVPRLPPTYGRPHHPYAAMMYPEFQYRPPPPSYQASMQEYRLRLLLLERSNPTIAALGSSLGHGPVTMVPPPPYRPYSANMRMLPHARVDEYSRPPSYRSRSSGNHNGDYDAAGSRPSLDPSVGHNHSHHHIIESPMHSRDPSLLSYLSQQSVDNMSVVSGHVANLQSVGNPATTTATVVTVVQAVSVGMDIGLGSTLYDEDGKGLPSLEDDKGYDPERDNKDGNLVRIVQTTDSSQVIGRDSVIVTVSGGGSNTSLWDTYHHHHLSHQTATAAGYVAQVHTSSSGTPNNNNIVSCNNGGTGSNSNVITMSDRSSSVGDQGEVQILAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC13</accession>
    <name>A0A1D2MC13_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mycosubtilin synthase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_16146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001915">
        <property type="protein sequence ID" value="ODM90538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC13"/>
    <dbReference type="STRING" id="48709.A0A1D2MC13"/>
    <dbReference type="OMA" id="FMMGTAE"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF6">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="571"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM90538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="871" mass="98006" checksum="980D760F1C496FCE" modified="2016-11-30" version="1">MEHNIQGKSMLQGSTKEFPNNTTVTQYFRLGFTNGQIQPSNLALVDGEKQHTFQQLDDISTKIANAILETIRNVPNHNPDGDRVIGVCIQPSDRLITILFGILKAGAAYVPFDITFPEERIGKIVNDCRPLLVICDGKSNVKSKFESVKNLTKVLTTDELYKKISPFAKNGANKSNVGADDTAIVLYTSGSSGEPKGVRLSHKAIFNRLKWQWDQFPFIPTEKCVFKTALTFVDSVPEIFGPLLQGFRLIVFDKTVTSQPPLFMEKLHVNDISRVVVVPSLLKAIFQTLHIVGKGEGRKLLSSVRLWVCSGEALSYDLLKEFFEIFPENFTLCNFYGSTEVMGDVTFVSYSSLRDVEVKVIAKKVPIGYPLANTIIYVLDENLQQVEQGHTGEVFIAGNNLAKGYVGILDSDKFLINPYSKCPDFTKIYRTGDFGSIALLPNGESALMYEGRIDSQIKVRGQRVDLSEIELVISGLESVSKVKVLCHHPGQPDQAVVAYIVPTSQQTTADQLKLEVGKYLREYERPVIRLLDEIPLLVNGKTDRQRLLKMFAAEQANREEFDDWSSLAILEEKLPIAKNLFKIISSVTGSSVQTIVENLDDSFFNIGGTSLNTVVVIVKLREIGYYISIPDFTSAQTMREILMRISPVESEPSKQNKRKQEYSVTLLTEKDKEEVVHIISYSFSRKGDLEAYVNVSYNDFANLIKSIWDEILQKKYSFVVRQASDRKPVAVSLNFDVYDEPSEADCTDEIKYVMDFLESVESKQRARLPEGKGKLLHSFMMGTSEDVDDSERVSLIELMEEQNLLIARKHKFEGIFTTNSNPLTMQIGRDLHGYEILSEYQVNEYVAPDGVKPFGLAPDSFKIICCWKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCI2</accession>
    <name>A0A1D2MCI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001835">
        <property type="protein sequence ID" value="ODM90706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCI2"/>
    <dbReference type="STRING" id="48709.A0A1D2MCI2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="15470" checksum="051434C27FC46E35" modified="2016-11-30" version="1">MGPPNHLTEAYVSGALAVVVFRTKGNSGQGFSLSFQGLGSTANSRGVEMVLSNVTGGEMTLLTWNNFSGTTNAIVLTGGHKFVDGYIKVLKLTISEKDFYTCGSENTCLCDSLRIFSFVNNVATQEGLFCNDSSTDPFTKLKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDD4</accession>
    <name>A0A1D2MDD4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA/RNA non-specific endonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15809</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001764">
        <property type="protein sequence ID" value="ODM90874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDD4"/>
    <dbReference type="STRING" id="48709.A0A1D2MDD4"/>
    <dbReference type="OMA" id="ICNDVSD"/>
    <dbReference type="OrthoDB" id="5960141at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF17">
        <property type="entry name" value="ENDONUCLEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="8">
        <location>
            <begin position="139"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="7">
        <location>
            <begin position="140"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="405"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM90874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="53684" checksum="9EC30CA1F853E856" modified="2016-11-30" version="1" fragment="single">ASVFSNTLRAGKDNDGCVLTLPSNLNFAPIVTDLATRQELIPSLASSNDFYYLKIERDTKIKANCGRGNKLRNHESYFYYLLTCVRGSEFQDDDEEPVILAEAIECTNPLQPRPRVFRNGTCFQNATNIEVEFITESSPRKYYSMCMDESTSGALYSTSYIDGEGIANGLGESTGNRPDFRGQEFYPFAIKQSYKWDPNAFEHLSDLLGSEDLVNEYFPTQQYRFSRGHLFPNGDALRKFERHSTFYYMNTVPQWQNLNGGNWQIVEHDVRVLAEKLRRTLKVTTGAFGVTTLTDANNNEVEIWLARDHTGRLRLPVPRLVWKVVHDPVGNSAVAFVQVNNAWVQKHNDILCNDLCNNLAWIRSSDFNVVRKGFTYCCDVTELRKSIPYVPDIKYSGLLGAAVEADERPDNESDSGFSDNSNYDDDSDSQNDDESDNDSSKSSGDEGDEERIYSNSKNSRVNNGASVFAQNTAAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDR9</accession>
    <name>A0A1D2MDR9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15651</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001695">
        <property type="protein sequence ID" value="ODM91031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDR9"/>
    <dbReference type="STRING" id="48709.A0A1D2MDR9"/>
    <dbReference type="OMA" id="REFAFEI"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000264">
        <property type="entry name" value="Zinc finger protein 236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="479"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="508"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="536"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="560"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="589" mass="67883" checksum="D3CB8110F775C72A" modified="2016-11-30" version="1">MGRVLCLLCGGDNQDVGRTEEVDKGTVFECFYKLFLVKSTNQGFWRVEEDRGEFPFCYKCSTQLLLVWDLQKKLEELELTLRKKVEEGESKFETGGAYQEDKRYYKIRRGILGDKVKCQNAEVVNTLRANPSTSRATGRRSNGGSDGIKSCSNGVSTLYNKKRVKGNPKPHQKLPSTTTRAARGGSKRVSKIPSRFEETSVISNDVEDDGSTQNDEEVAHHLPLKCEQTEEEVESSLDNNYDESPDQEQEQLCSMGASFPSSPAGLDMDFEELEEPPPKKMREVRRKPRRKYTEDLDNEEDDEEKKPPKSLSRRKSKKSHQESDDDDDFNPSESDDDDKFQCTICYKQLSNQFNLRFHLQTHNGVPPEQLHPCPVCNRPFRRSDWMKSHLWSHYSEEEKQEAISHGEKPPCRSLQKNYQCELCPLAFSAKYLLKSHQKTHFEPISQRQQLCSICGGSFVNLKNHMFLKHELNREEDKKHACGQCGKRFALPSALRNHKMQVHAKEKAWKCEFCPREFAFEIQLKTHLNSHLGIRNFKCEKCDAAFTRNGSLKRHIGIYHEEGSKPGRPSYVRGPEKIKLEERKGRKNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEL2</accession>
    <name>A0A1D2MEL2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">General odorant-binding protein 19a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001543">
        <property type="protein sequence ID" value="ODM91457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEL2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006170">
        <property type="entry name" value="PBP/GOBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01395">
        <property type="entry name" value="PBP_GOBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903896" evidence="2">
        <location>
            <begin position="24"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="18979" checksum="F9DAA93326C51AE3" modified="2016-11-30" version="1">MENSKALVLLLAIGFCCVASTLGESCMGKLTQSANFVVAQTACVKNLKLNVSDIESLTPATLKENHFDDKCFTNCTLESMNAYHNGTFKKEAILEQLKAVVPETDHENLSKVVDTCVEKATQKPGGHKHKHNKNGNEKKTKDIKLHAGHMGKCSCKRAAKFVSCMMENDIMTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEN7</accession>
    <name>A0A1D2MEN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">VIP36-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15223</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001542">
        <property type="protein sequence ID" value="ODM91459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEN7"/>
    <dbReference type="STRING" id="48709.A0A1D2MEN7"/>
    <dbReference type="OMA" id="GCTADIR"/>
    <dbReference type="OrthoDB" id="270293at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000017">
        <property type="entry name" value="Vesicular integral-membrane protein VIP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF45">
        <property type="entry name" value="RE50040P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="13">
        <location>
            <begin position="62"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="361" mass="40619" checksum="A36CC6B228288471" modified="2016-11-30" version="1">MKFPDVGARIVDLSGGIGLYTPVQSSTSHLFVVLLVIFNILSSHTILAQYQQPVQADWNTADYLKREHSLSKPYQGAGWQIPNWDFQGSTIVTNQYIRLTPDSRSQQGSLWNAAPIRMHNWEVQLQIKVHGRGKDLFGDGMVFWYARDRMIPGPIFGSKDYFMGMAVFVDTYSNHNGPHNHQHPYVSAMINNGTMHYDHDRDGTHTQIAGCEAKLRNIDQDAWLAIRYENEVLTVSTDFLGKNAWAPCLKVEGVKLPTGYYFGLSAATGDLSDNHDVITVKTYELESGGVRPEDDRSRDSILPSALTYEAPREHVDDVKPGWSGVKIFLVTLFSILGVIAVGVVGIIVYQNHQQNTRKRFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFX0</accession>
    <name>A0A1D2MFX0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001394">
        <property type="protein sequence ID" value="ODM91863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFX0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="478" mass="51663" checksum="2FC629D0DC3810F6" modified="2016-11-30" version="1" fragment="single">RHPQPSSSRADTSHPKAGPSGLFRHYAGVPKKESVPQVVDPEADSDELECLGSFPIEKKPPLAVITLSSDDEESPRVKHERTPPLATTPDPETELARYLATELDYQVSDFNGLLDISFSPTTTPPPRVIGGEHYLSSSSTTPLMPDFPTLTTRSISDAEPSTSAAAASRLDFTLRSPRLNGFTPEKDSSNKQTTEENCSKKSKKQKHSKSHKRPRMVISSSSEASDDDDEASNSRSRSPVTSKRSHSTHSSSASSSPLKRKSVAGKSLGAMSSALLVFTSSDSDSPDSDDSDYGTTLTERKSSSSKKRSNSSKKKHKVKKSKKSKKCKDKDKERSRKSGSSSKGNGDSTSPACAVPGGSNTSNTSSGNNSTLAHKSKKKSSTRTVQAPSSSSTTNMNIYDFDDHPSGLLDLSFNHRADNTPMLPQVVDKDDDDFRIPPSAAPSSSSTVDPSALFGSPSRTIFHAWWEDYASERRSWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG29</accession>
    <name>A0A1D2MG29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetraspanin-13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001372">
        <property type="protein sequence ID" value="ODM91956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG29"/>
    <dbReference type="STRING" id="48709.A0A1D2MG29"/>
    <dbReference type="OrthoDB" id="5845060at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="13463" checksum="D6B06A473B9697C6" modified="2016-11-30" version="1">MRCTRIPRRGSLRSEPLGRHTRCLATRYSGSACAAACPTAAATSAPVPSVRTRFRAICGCTGLSLNETCHCPTCSVKIQEVIGEAFQLTGGVSLFFSFTEFIGVWLTVRYRNQKDPSGGNPSAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG79</accession>
    <name>A0A1D2MG79_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 2 subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Eukaryotic translation initiation factor 2 subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_14673</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001355">
        <property type="protein sequence ID" value="ODM92007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG79"/>
    <dbReference type="STRING" id="48709.A0A1D2MG79"/>
    <dbReference type="OMA" id="DVNEHQR"/>
    <dbReference type="OrthoDB" id="1685042at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.190:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000795">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1130:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="16"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="292"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM92007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37741" checksum="1A3CB5108151E3E0" modified="2016-11-30" version="1">MPLSCRFYKEKYPEVEDVVMVNVKRIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSVNKLIRIGKTEPVVVIRVDKEKGYIDLSKRRVAPEDVEKCNEQFSKAKAVNSILRHVADLLGYETDEQLEELYTKTAWHFEEKYKKKASAYDAFKNAVQDPSILDECGLDENTKDVLLKNIQQKLMSQSVKIRSDIEVSCYAYEGIEAVKKALRAGLECSKQDMPVKINLIAPPLYVVTTSTPERQDGITLLQEAIGRIEETIKKLGGSFNVQMAPKVVTALDEAELARMLDRLELENQEVAGDDDEEDDEEENENDDGEGEGEGDEPEGKENGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGC4</accession>
    <name>A0A1D2MGC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbonyl reductase [NADPH] 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14663</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001353">
        <property type="protein sequence ID" value="ODM92023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGC4"/>
    <dbReference type="STRING" id="48709.A0A1D2MGC4"/>
    <dbReference type="OMA" id="KGPYFLM"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="27104" checksum="962F911F35695A18" modified="2016-11-30" version="1">MAEINNFSGKKCLVTGAGRGIGRAVVAELCARGATVYAVSKNPENLKALKKEFPNVIPVCVDLSKPEEIGKALEPIETLDCLINNAGVIEPAEMLQVSAESFDRQFNVNVKAALIVSQIVAKKMIERGEGGSIVNISSINAQRPALGIGLYSCTKAALDMLTKSLAMELGHHKIRVNSVNPASVLTDMSSTESYDDEGKVKMQAHHDRLLSRTPTQTLWMPVGDVVNAVLFLASNATSQITGQCLGIDGGYLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGP2</accession>
    <name>A0A1D2MGP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Sodium/calcium exchanger 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_14506</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>Ca(2+)(in) + 3 Na(+)(out) = Ca(2+)(out) + 3 Na(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:69955"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001305">
        <property type="protein sequence ID" value="ODM92176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGP2"/>
    <dbReference type="STRING" id="48709.A0A1D2MGP2"/>
    <dbReference type="OMA" id="AICIMCI"/>
    <dbReference type="OrthoDB" id="418484at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098794">
        <property type="term" value="C:postsynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005432">
        <property type="term" value="F:calcium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051171">
        <property type="entry name" value="CaCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004836">
        <property type="entry name" value="Na_Ca_Ex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878:SF76">
        <property type="entry name" value="CALX-BETA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878">
        <property type="entry name" value="SODIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01259">
        <property type="entry name" value="NACAEXCHNGR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="16 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="18" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="7 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="722"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="753"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="796"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="21">
        <location>
            <begin position="335"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="21">
        <location>
            <begin position="451"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODM92176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="862" mass="94371" checksum="8BE63EC34681363C" modified="2016-11-30" version="1">MGTWFPIYATTNVGQDVAAAVGLFLLICYFFVGVAVASDIFMNAIEKICGSTKSIKTTREEEGVVITDTKDIPVWNETVANLTLMALGSSAPEILLSVIEISEGLGQQSPGELGPGTIVGSAAFNLMIISAVCILSLKEGATSRIKVYQVFTFTCVTSVFAYIWMVVVLQWISPDEVELWEAIITLLFFPLLVGISYWADQEFCLTGRPKTKRWSTSSEPAAVGGPEEDGRTFFFGDESDELYDAEGNVDKKALQKLYHKLTEVADLTPEEIASILATKLIQGKQHTRMWYRMQASRGLMGGAKLLPVLTEKLKEVVEVINDSGSHHVRGSVLNSHVSSMHAVNKALVEFQAATFAVTESIGSFEVVIVRTMKEDVGFEVKLESFDGSAKKGSEYEQVSEILKFDPYVLEVRHTVKIINNNQWNPDSNFFLKVSIPLESQEKALTGQTKVMEVIIEDDDKPGKLSFPKVGYVFNDSGPTVNLEVERTGGSDGVVSAVWKVLPGPNCKLIDPELIGKIEFKHGEMKKNISIPLKPHNGAVEGKNESFDVTLSEPAGGAKLGKVIRTTCAISTDTGFKLEITNVMNMALEMNEEANEDITYKEQILEALMPNGGQLDTATKKDWALHIFTFPFKFTFSLIPPPHMCGGWLCFFLALFAVGLLTKLVGDAASAFGRVCRLDPTITAITFVALGTSLPDTFASRIAAMNDKTADNAIGNVTGSNSVNVFLGLGVPWTIAALYYRFTHEGKEPFCVPAGSLTFNVIVFTVCALLAIFVLTLRRYSEKCGRAELGGPSTTKWITASFMIFLWFFYIFLSAVQVFLEKNGYDISIVFKTGDINVPTQCQTLVMDYAMGLPPSYPPSGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH67</accession>
    <name>A0A1D2MH67_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein tweety homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_14363</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Probable chloride channel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the tweety family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001272">
        <property type="protein sequence ID" value="ODM92315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH67"/>
    <dbReference type="OrthoDB" id="187568at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034707">
        <property type="term" value="C:chloride channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005229">
        <property type="term" value="F:intracellularly calcium-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072320">
        <property type="term" value="F:volume-sensitive chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006990">
        <property type="entry name" value="Tweety"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12424:SF8">
        <property type="entry name" value="PROTEIN TWEETY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12424">
        <property type="entry name" value="TWEETY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04906">
        <property type="entry name" value="Tweety"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 13" id="KW-0868">Chloride</keyword>
    <keyword evidence="9 13" id="KW-0869">Chloride channel</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="159"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM92315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="216" mass="24104" checksum="AC688A8FB6C60291" modified="2016-11-30" version="1">MELSQASISREVSEYYLNCQPFRTELYPFRELVLEGQHSLEGAQHTLRVINSIASNYYSPNDVDEIVDGLFKELYNVESYLGETSARAECQPIQTHWMKGVDAVCSTSLFGLALLLVSALVSALLFTLLVGFDSHTWIYIQRRKRYLQQEECVSFLPSQYDGGPSGTGTGTGTSSTGQRCRRSGERGAGSNSPYNLVAHWDTQPTPLSMLTRESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHH3</accession>
    <name>A0A1D2MHH3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001222">
        <property type="protein sequence ID" value="ODM92457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHH3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="12863" checksum="DF9DB14CF9D6C3DC" modified="2016-11-30" version="1" fragment="single">VSVIGVLYGSFIFNYDGNIPCMTPLHIYALLSCGFGFSCLIYNCIRRKSDPGERCSAEPNESKSRTESTSENCKLDELQGTVIAPLGTSKGGQNANENKWRKLLRCKRECGSNCRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJY2</accession>
    <name>A0A1D2MJY2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001073">
        <property type="protein sequence ID" value="ODM93124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJY2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="66" mass="7725" checksum="4E90F3CC5AFA96A4" modified="2016-11-30" version="1" fragment="single">MASSEAVTLCRCYDSHRNVHRDCQINGSGRIQRLKPKKDGLKEYEKLDNLMVLLRNKEHFKILPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLH1</accession>
    <name>A0A1D2MLH1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone H3.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000904">
        <property type="protein sequence ID" value="ODM93837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLH1"/>
    <dbReference type="STRING" id="48709.A0A1D2MLH1"/>
    <dbReference type="OrthoDB" id="420022at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="3">
        <location>
            <begin position="111"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="22714" checksum="F03713E898415103" modified="2016-11-30" version="1">MKIELSDLPNRRKLFLWDQRVENMKASTTRRRSAPYTRDRPEVATEAATLPVEDANSSSQINCVVRDCADGKREVVGNLASGDQPSEGSSGENPTESRGASQMRLLGVTNAEIARYERCTELVIPPLTFQRVVRDIMKPLCSPNDPVRIEAGALAILQDAAETHITSLFVDGSISCVRRKGKELYPRDLALARKIRGNNPHFLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLJ2</accession>
    <name>A0A1D2MLJ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Intraflagellar transport protein 46</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_12935</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000924">
        <property type="protein sequence ID" value="ODM93745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MLJ2"/>
    <dbReference type="OrthoDB" id="2119217at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022088">
        <property type="entry name" value="Intraflagellar_transp_cmplxB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12317">
        <property type="entry name" value="IFT46_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="676"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="676"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="779"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="817"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="848"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM93745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1301" mass="143775" checksum="1458C95FFFED46DD" modified="2016-11-30" version="1" fragment="single">SCANCLEPFDFIVVGGGTGGLVVARRLAESRKHSVLVLESGGHPKEGNEIPAYAPRSVSDPDIVFRYTSVPQQNAAVRFNGFARIISGRMLGGTSSLNYMHFNRGSPHDYNDWARSTGDASWNYSNMLPYFKRIETYVGDYPSGIENMLLKCLLVQIFSNLIELVLGIRYPNSQSDQHGYSGPVTISRPSYAPGLDYWIEAGEQLGYRIEDANGPQQISFSRTEFSKKFGRRASSYTAYIEPILASTPNLQVLTNVNATQIIFSRKRAVGVRFETRLQNSPPSENVVYAKKEIIICAGAYGSPILLMRSGVGPRDVLEAAKIPIIHELPVGKNLHNHAAIELDFIINKSSAVVDPARDFTPENLELWKRTGDGMQTLNKSQYAYCFCTCIKTLFMLAGPYSGAGGGTGQAFIASSVAKSAGETNWPDIQLTMAHSTESYLIVDNSPSNFTESAEVPMSVQVFVGRPKSRGSIKLNPEDPNGPPIIDPQHLIDPRDLQIALDGIKETLRIMEATESYRRLEASFSSVELPACMEFEERSNEFLICYIKHLSQTGCHPAGTMKMGRGPQDSTAVVDSQLRVIGMDGLRVADASIMPTVVNSNTQAAVYVIAERASELILQNWQSSLKRFRFGRKHVRAVMAFPRLLCGAPEVCEEDDDVEDEYELLAGRKRVGVSPVRRGPFRFQQQQRPSRSFVRGSTRETDSLGMSDEGSPAPASLPPQPQLQQHEQPTPKKKSLSSKEFIGSQSPQQSQDGGGGEGSVQHGNLISLASSYAKKLMSGSDKKDKPPADVVEATKRPPKGSGHEPKKQPQQQPPPPSSSSKMPQNPQAMPQAPLGQPPPHPLPQQSRSEEDEDDDDDEEDEYDDVNMAQIEGLLRRVEKPPSSFFTTRPFPPPAESPTPTSGPSILEQCYDYRAQVDRGGGGDPYSLRASPHPTALGYHPAFGPATANLMNFAGSLSDSDSEISISEGDLNRMDSLMAMYTNSPEALVGDPESMIMNLPTSQLSNMSMVDEEVLENMLAQRKMWEYQLDVKRESLRRRTLVMSDYPGVHAPGHTVYNPQDYEHLNVSPEVKELFHYITRYEPPGVGSQMDVKLKPFIPEYYPSVGDIDAFIKVTHPEIQDDTLGIKCLDEPSPFQSDPSVLDLRLRALAKQSSSKSVVVKKIDNVGKNSKIIENWIKDISDLHRSKPSPSVHYSKPMPDIDLLIQEWPPQVEELLKNISLPSAELDCDLATYVDIVCNLLDIPVYKSRIQSLHVLFTLYATYKHFNHYGPLGMASGNDLDNLLPSSTSARLDDTDVDRLQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM42</accession>
    <name>A0A1D2MM42_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Scavenger receptor class B member 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">SR-BI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12737</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Caveola</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CD36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000885">
        <property type="protein sequence ID" value="ODM93945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM42"/>
    <dbReference type="STRING" id="48709.A0A1D2MM42"/>
    <dbReference type="OMA" id="ECIANSM"/>
    <dbReference type="OrthoDB" id="195015at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005901">
        <property type="term" value="C:caveola"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002159">
        <property type="entry name" value="CD36_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923:SF110">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11923">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01130">
        <property type="entry name" value="CD36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01609">
        <property type="entry name" value="CD36FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM93945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="473" mass="54051" checksum="DFF180599DA7ECC6" modified="2016-11-30" version="1">MIIISPDVNPELYSAWIHPPVPIHLKVYLFNVTNSEEVQRGFRPKLLEVGPYVFRENRTKINIHHDEDTDTVTYKEHFTYHFEQQLSGDLKLQDEIIIINTPYVAAAIKINNELPWPMDSFANMILIQYKESLFIRRTVEEILFKGWTVPFLQQIETDIGLTLVLNNTFGLLIGQNDSAQGPYTVARGVSDKSQFGTILKYKNESELSYWPKSSQCNKIQGSDGTIFSPFVEKRTVLKLFNSDLCRSLYLSYNQSIDFEGIKGYRFTVPPSVLADPRENNENHCFCPNMEHEPDKCLKKGTLDLGPCRDSAPVAMSTPYFLDADPQYLEESGLMPVRSEHETFLDIEPMTGIIMQASKRIQINLILKRVKGIASISKVPEMLFPLIWMDEVGESMHMLLGIICTTIKLIVITSTKASRKMIIEVSTSLDVENRLKLQSILYNVRLLDFISKMIPIATLLVVLSIVVKRKFSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMM6</accession>
    <name>A0A1D2MMM6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome c oxidase subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000862">
        <property type="protein sequence ID" value="ODM94095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMM6"/>
    <dbReference type="OMA" id="GCATIHI"/>
    <dbReference type="OrthoDB" id="19300at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="18902" checksum="0176617CF7592135" modified="2016-11-30" version="1">MVSSCCGLMNLQKACIITASIEIVLSCAFLFYCVVTLAIETPLAVEERNNAVETPDPSRFHAMRVVLSGMNALFWIACLFLGFILVLGAKQRDLKRLRTWFVLTCILSVLFIVDIFIEAFSMTAPAPAIASPILGTILQCYMLWIVMEYMEFVAHNGCATIHIKAQQEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPY3</accession>
    <name>A0A1D2MPY3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ninjurin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ninjurin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000737">
        <property type="protein sequence ID" value="ODM94874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPY3"/>
    <dbReference type="OMA" id="CEAFIGI"/>
    <dbReference type="OrthoDB" id="10350579at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042246">
        <property type="term" value="P:tissue regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007007">
        <property type="entry name" value="Ninjurin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04923">
        <property type="entry name" value="Ninjurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14070" checksum="C327C34C05F5A444" modified="2016-11-30" version="1">MKSFHDYATLKTTGQLVMDLGSISTHICALVALLRNYDVHNNLSTKVLLWVLVGTIIFQVIVAVGLYIFRTLDLNSEVNHQAANRWNIVFFCALFLVAVLETFIGAFEKFGMDHVPYISGNGTSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQQ7</accession>
    <name>A0A1D2MQQ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative chitinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000684">
        <property type="protein sequence ID" value="ODM95336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQQ7"/>
    <dbReference type="STRING" id="48709.A0A1D2MQQ7"/>
    <dbReference type="OrthoDB" id="9991479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF110">
        <property type="entry name" value="LD43683P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904399" evidence="7">
        <location>
            <begin position="28"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="30"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="99"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="164"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="253"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM95336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="38342" checksum="7F0C60BFC092DC56" modified="2016-11-30" version="1">MKKFICGVGGIFLQAVLLSLLIAGTFGDPKEECQPRNKTYNIADSKQCDMYHECGKAGKPFERLCDDGFQFSEEINACDYPHNVNCSGRELLQEPKSVHPHCPRMNGFYAFPPADSCQKFYHCLEGNAYEKTCPEGVIFDPKLGACIHPDLSHRKDCRPDIVLNFTCPNYGKKFARLRFGDHDRVSHPTNCRKFFICLADGKPRVGGCPLGKVFNPKLGVCDQPKKVPQCKDYYGKRDPAKLAKLAELGEEASLNLNEDDEVSEPHIETDDSEEEQENEAVESKNANANKGKKFHTKRQAPAFAPDATQVGPENLLTGPQNQNSGKTSVVDSDDDSADEDVDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS99</accession>
    <name>A0A1D2MS99_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000619">
        <property type="protein sequence ID" value="ODM95802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS99"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="14456" checksum="2F68A86D7CC6F99D" modified="2016-11-30" version="1">MSLGISKVRVEVVLKKMWSKPMCCLRLRSGLKFIAFIDLILATALLLISGGAFFYYENHYQEAVTFLHNPPPIFDMFINFRKIEGTTIRVLLSFGLFYYLQKVALGFILFFAAVKVSLRFLTLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSU1</accession>
    <name>A0A1D2MSU1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000584">
        <property type="protein sequence ID" value="ODM96076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSU1"/>
    <dbReference type="STRING" id="48709.A0A1D2MSU1"/>
    <dbReference type="OrthoDB" id="6060579at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01671">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000077">
        <property type="entry name" value="Putative Serine/threonine-protein kinase/endoribonuclease IRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="107"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM96076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="649" mass="73098" checksum="263E55169497AE82" modified="2016-11-30" version="1">MEQWQKEIIQANLPDLIGNTICNCVMLAEFSASGILSQCDIEALKSHEDNSAKSYSFYTILMKKRDAFPKLLEVLQETKQTGSLYTLLTGAMERKNKGLGEIKLLTYDENAILGEGSHGTVVYKGQFSGRNVAVKRINNATFNAKENATLMQEVDVLQACDSHENIVRYFGSSLAINHIFIALELCDITLKDWVASKTINIQPLEVLRQVTVGLEWLHSKQFIHRDLKPENILLTHELSKVKLSDFGLSRRVANGKSYALTAGFGTEGWVAPEILSQAQDGYCNQIKFTYKSDIFALGCICYYVLTDGKHAFGDHFRRTANILDGKLMVKETDLIYAIPQNIKVIELMVSNEPTDMGPSDDKNKMAHTNGNFSTETCLNTLICRLAYDDITMGHLNAAGEVELIKNLAGEFSTRLQIGQTRQNELVCVAALRHNYFVKSWTLRDILANSNHEVLYEGKLVEMTLEFFLGQMLKILKPFAESKTCKIFNKIIIAVPVPFMWGDTANELQTALKNYAGFDDAKIVTEISCLARSYVKNNYPSEEQELLVLSQNFTYKKYLIGDINHGVDVGLYKCRPDSEIEKNPQRLTLENCLVGTFQNRKPRSVVIACDLKEQYEKIKGETARYDLIVHTFPNHKLEIIKGAVLSLSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT80</accession>
    <name>A0A1D2MT80_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-1,3-glucan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000577">
        <property type="protein sequence ID" value="ODM96111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT80"/>
    <dbReference type="STRING" id="48709.A0A1D2MT80"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF55">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="22021" checksum="C14B48FB6460B1F3" modified="2016-11-30" version="1">MAGGDWIEPVISLLPAEKFYGEDLRSGQIHLVDTRGNRNLFNENGIHVGSEQTCPDIRFGTGDNRKVEYYCLNTAENQGFDRDFHLYELEWTPDSITLKIDDEGVFSTPFPRPNMYKLWSGGREIPNPWEVEGTENPKLAPFDKEFYLAIGVKVGGISGFFSDDYSNRPYSKPWKNTDTINKSLQSFWVAGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTH7</accession>
    <name>A0A1D2MTH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000582">
        <property type="protein sequence ID" value="ODM96094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTH7"/>
    <dbReference type="OrthoDB" id="10502185at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="524" mass="59663" checksum="8FB4968D138456AF" modified="2016-11-30" version="1">MRNGKRYTDSDSDSGDPLSDPLSCEPLSLIVPNTPYHQKSDGGKSYMVLSTDTEGLKQSRAASNDEIVKQGDRAISFTSLLNSITSLETFLQTGSAYLLQTLNSSQRIIWFIVFILFAIFFYPLLSTLLVGGLCALFICGHQSDDKKRTSRTAKWTVTGFSQQLRDGFLASPAFLDKSGQWRMVVKQKRGMDGVQTSFGLLCTDIYPQIELVTANVTFFCTNKYGQELNTGGMRNLKFQQEYQCAGDAGFSRPTRFTRRQLGEDEAVTIHCSVEFHKKTVTFLKTLVRNLREDGSSGDGERKNKKGKNIVTEHGTILPGNLEFQDDDDSNFPSVFRPLTRFVHHSETKTFVWEIPDFTTLLESSELWGIYSPQFFLNSHDICSIWRMKLLEVQGVFRLHVQLRGLPRSVKQVKLWYLLQLVDNIGDSVIPEHAVCRVKYPDHMNLWDTTRHILYRRETILERFVTPRGALSLRISLQMEPNDLALMEVDSDDWIQSNQDLPLLEEPHGVLKELPYAPKRAMLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUN3</accession>
    <name>A0A1D2MUN3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10059</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUN3"/>
    <dbReference type="STRING" id="48709.A0A1D2MUN3"/>
    <dbReference type="OMA" id="ENFCVAT"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904579" description="Chitin-binding type-2 domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="227"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="312" mass="33372" checksum="60F6928900091017" modified="2016-11-30" version="1">MKLSIILLAAVAGCLAVADFARADGSVEQEALNAAVHEDLKQIYSVQEEALNGKGSKESDESKSKESNESGSKQSNESGSKESNESDSSESSESDSKESNESDSKESNESDSKESNESDDSDSDSNEDSEESGSGENRPTTGRPTTPTRPTRPTIPTRPTAPTRPTRPTTPTRPTRPSTTQRPTRPSTTVRPTTSATPEPSSTAQPTTPAPTTTSTTTLAPPDGECDVVCRPGDHYLVNPVDCGSFYQCSNGVPIFQPCPEGLIFDPTLNVCNRPEDSPPCKPSQCLAVMIHYRVGAIWIAKPAHDFKRPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUU2</accession>
    <name>A0A1D2MUU2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Treslin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000496">
        <property type="protein sequence ID" value="ODM96860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUU2"/>
    <dbReference type="OMA" id="ENTHHSA"/>
    <dbReference type="OrthoDB" id="6341942at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="799"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1189" mass="134475" checksum="E712F666C1086335" modified="2016-11-30" version="1">MVQSSVVFLIDINGIERAPGNINNGEESGQLDASHNDTMEMFPFRGEEVDEDPLKLQCDDLKWLKDFVLLTLFKEANNGTDYDFGKVQWAFKFYDSTRHVDYRDGRQFMPFDYESFTSFEKQLDQRMGPSSVDIKNRADSEVEFHCPNIKFLTDALKIITGSLAWTEQQDSSNLSRSFNGESKNARNLVFACLKVPRTENEILDFTDLQSISSSKDFMSVLLPSAFSAKFHHAFKIQLNFVDLRTSYDNNTLGIKSEKELERKWNVEYPRHLGKCLQYLGGGRVLPMPNFPKLRDESLKFGLVPYQIYLKSRLQQASQQNENLPSHIQRLAPKKISPDLDTSSVNRSMKSGGASLLEASYSNSHNHSKLLRPFRMSAGYDSEEMFEYHRELVAGIKPLDRAREVERKRKRMDYDVDDYYSSRYDRHHATLRDDEKYDSDEVDSQCERDQRMESWINEGVFTAKRKKPMDHSSTTVPMSRPLSLNKSSHVFHEPAPKLPGTRSTKMLRKVNRHSQKATAVETNNKRISNEGMDSIKQIAQRQEKELGAIKHRLRLHLDGELDMYENDGVKWLKTLKKQMQSFTEMILQEDRPSLVALAQALVNNASTKFTQRLNTLRPLYRNPITVKDLLENILLSELQKINTKIISARENPRDKFSPSAPVSKNMQRVFAFREAELQIILRLEIAWCFVEPDDDVTQDLLTEIVSVLQIISVYRSNPPIDHFINTVLLPTYSQCNKFLRALYKKMNIALPPQLTIDGSPVQNSNRRDDDSSIISSTSSAMLYPEDSASQLNVHKRHRPSTSFKRSTAPTSSRKPTSGSKRVKRQIMVAHASNPRLSSSQYLMDRTDAHKNTTGVNQKASPKRVRRNLFDVQIKDRKDSKTLLTLGSSSRLTKSPVFKSPKGKSPLSPSGFFRAARSRKQLILNNQPADNRFGSPTLNADVLCPESPATPGCDRRSVASRYAATNASGGSGERQRVIQESPEVMKNDFDNRPMNRVASLSFYSSGCSAPKSRAWGKSEANLIAEKIKNSVDLRSSEMIPDDLTQSPYEKPSRNPSDSTDDTPCTRLSFCDDSYTEKNHSPMPLGSNSQSLLDITGPAPDLDNPNIAALINGPFFPLATTALDIPLKAVQNEPGKGNSPSFSNNIVASPNNLQTPSKRVQFNLNENLVNTPSSARRTSTGTPKSILKETHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVE1</accession>
    <name>A0A1D2MVE1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Membrane metallo-endopeptidase-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_09767</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000490">
        <property type="protein sequence ID" value="ODM96912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVE1"/>
    <dbReference type="STRING" id="48709.A0A1D2MVE1"/>
    <dbReference type="OMA" id="STMATHI"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF224">
        <property type="entry name" value="NEPRILYSIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904615" evidence="10">
        <location>
            <begin position="18"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="12">
        <location>
            <begin position="101"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="11">
        <location>
            <begin position="551"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM96912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="758" mass="86565" checksum="810CD7E28CB1001B" modified="2016-11-30" version="1">MERRLLVVVCLFVVACAALVVALASSNSISLLRKVSPNSEYMPSPEALVGEGREDGGPNSYIQNGNSLPAAGSLPYETCETKGCVQAAATLLSNMDETVSPCDNFYQFACGGFVQNTIIPDDKTQMTTFGMLNDKLDEQVRRLVEEPIKEDEPKVFKLVKNLYQSCMNKSLIESNGLEPMHDVLKMLGGWPVIEGDNWKAEEFTWINSVYRFREHGYSVDYFIDFSVTTDVKNSTYRVIDVDQPALGLSREYLTKGLDEPEVKAYRKYQVELAVLLGAPRATAEKDMLAAIEFERKLANYSLPREERRNVTKLYNPMTIKELQEKWTTIPWLDYINRLLPESVKVEENEIVIVTVPEYLNKFEKLIQETDARTQANYVMWRAAAASVSYMSEAVRKLQLDYTTALTGKGEREPRWKECTAITSASLANAVGSLYVRRYFKEESRLNAMEMVKDIKVSFLDILDEIDWMDSTTKERAREKANTMQTHIGYPSELLNNTKLIELYDGLEMNNRDYLMNVLNLTKFGTEYAYKKLREQVNKTDWISHGRPAVVNAFYAPLENSIQFPAGILQGIFYDNDRPRYMNYGAIGWVIGHEISHGFDDQGRQFDSDGNLYDWWEPTTKEAYLRRTQCVIWQYGNYTATEVGINLNGINTQGENIADNGGIKEAYSAYQAWVKRNKPEPRLPGLKSYSSNQLFWLSAANVWCNKYRKESLKLRILTGVHSPGEFRVRGPFSNMDTFARDFNCPVKSAMNPEHKCAVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVF7</accession>
    <name>A0A1D2MVF7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ribosome biogenesis protein BOP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09747</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000486">
        <property type="protein sequence ID" value="ODM96932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVF7"/>
    <dbReference type="STRING" id="48709.A0A1D2MVF7"/>
    <dbReference type="OrthoDB" id="5571054at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="8">
        <location>
            <begin position="209"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="79"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM96932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="246" mass="27561" checksum="A07019C213519B3A" modified="2016-11-30" version="1" fragment="single">MVKRKLDPANLEVVASTSPKDAVNKAGPKSERLRLRSAAINLSPAKNGKEQKEKTKEVKSAPVKATKKLTVKKGKVDAMEEESEADDENEAPADDQSEEDDSVVGTEEDDEGDDDSNESSEEEEDASGEEEDDEAKSDNESDAESSEEEDDEGIENDNPFEFSEMNEAVSETVETAPHPNPVNGNEYEEDSSDEEDIRNTVGNVPLNWYDEYPHIGYDLDGRKLIRPKQEDKLDEFLRRMEDPNFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW91</accession>
    <name>A0A1D2MW91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Papilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09466</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000463">
        <property type="protein sequence ID" value="ODM97201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MW91"/>
    <dbReference type="OMA" id="IVMLVQD"/>
    <dbReference type="OrthoDB" id="5950222at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="CDD" id="cd22639">
        <property type="entry name" value="Kunitz_papilin_lacunin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00199">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.830:FF:000001">
        <property type="entry name" value="A disintegrin and metalloproteinase with thrombospondin motifs 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000020">
        <property type="entry name" value="Collagen, type VI, alpha 3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000004">
        <property type="entry name" value="Tissue factor pathway inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.830">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013273">
        <property type="entry name" value="ADAMTS/ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010294">
        <property type="entry name" value="ADAMTS_spacer1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010909">
        <property type="entry name" value="PLAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF281">
        <property type="entry name" value="PAPILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05986">
        <property type="entry name" value="ADAMTS_spacer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08686">
        <property type="entry name" value="PLAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19030">
        <property type="entry name" value="TSP1_ADAMTS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01857">
        <property type="entry name" value="ADAMTSFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00217">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50900">
        <property type="entry name" value="PLAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="1498"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="1557"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="1616"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="1676"/>
            <end position="1726"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="1737"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="1808"/>
            <end position="1863"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="1870"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="2000"/>
            <end position="2050"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="2059"/>
            <end position="2110"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="2129"/>
            <end position="2179"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="13">
        <location>
            <begin position="2291"/>
            <end position="2341"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="2347"/>
            <end position="2458"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="2618"/>
            <end position="2713"/>
        </location>
    </feature>
    <feature type="domain" description="PLAC" evidence="12">
        <location>
            <begin position="2719"/>
            <end position="2758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="756"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="795"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1926"/>
            <end position="1989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2190"/>
            <end position="2220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2417"/>
            <end position="2482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2566"/>
            <end position="2594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="760"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="820"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="854"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="874"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="893"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1030"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1080"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1939"/>
            <end position="1989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2192"/>
            <end position="2202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2418"/>
            <end position="2427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2456"/>
            <end position="2467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2566"/>
            <end position="2576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2584"/>
            <end position="2593"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="96"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="107"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR613273-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM97201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2792" mass="307886" checksum="FA7C0C4334AC9342" modified="2016-11-30" version="1">MLAFRVKKLFHQILDPFLTHSLDSPIRELLNLQDILQDSSPPKVRTKRIPHEYFDFNEIDDSAPIYVTEDGDETDKISSSGPWTDWSVPSECSRSCGGGVASQARECEGECTGPDTRYFSCNTHACSDGVIDFRADQCSAFNNVPFEGRFYTWLPYTRAPNKCELNCMPQGERFYYRHKKKVIDGTSCAQDSICVNGNCLSVGCDGILGSRKRQDKCRVCGGDGSNCNTVQGIFDSNELQVGYNDVLLIPAGATNILVRETQATNNYLAIRNTSGHYYLNGNWRIDFPREIHFASTTFHYERKPHTFFAPETIRSLGPISEAIYVVVLYQEQNPGITFEYSVPKGVVVETEDGTEYAWIYDDWGECSRDCGGGTQNRNVNCARRSSSTLNWDYVEPHLCDSNIKPETFRYCNYEVACPVRWHVSTWDDCTAPCGSNITGTQYRNVFCEQEIQGVSALVENDKCVFLLGPAPDKLRNCTSTNTEECTYWFVGGWKGCSSLCGPGYNTRVVRCISKDSLGRIVIHGDEKCVGDKPVEYEYCFLGPCEGVDWIAEGKWGECKVPSIPTCNSPTSANRGTQSREVYCSDAKGKVYEENYCHVYRKPNTTQSCELDFNPAEDPSCKYTWYATQWTDCEFQSCSERNKGKRTRRVICGTVLNDNMSMKVVEEDNCNATKTYHNEEDCEISSEEVEKNCGDEEARSRRGVWFAGPWGECSKKCGGGRRTRAVLCMVGNRATTDVKICGEDDVIFTSEDCNPGSCDDLPADEESVTEAEEETSTVTEEPCEVDDYYDEYYDEEEEPMGITSPVTGRSTRSVDASTESTTDDVTEDMTESSATEDSSGATDTPMDDITGDTQATSEEGTTATGATDEMDTEATETSVTSETTQAGTTESVATGGSTEGVSVTTPGGTETTSGGVETTTGMDTTTGGTSTAQPTTTEGSMTTTDAATTTTEEPSTTSTEPPTSTTTEEPTTTTEEQTTTTEAATTTTESITTTTAQMTTTDRDVSTTTMGATDDGMSTTTSGGSEATTTLSSITEMDGSTVSGGAVSTEPPTTLIPPPEGGYNYDYNLEGAPIQRLLGGSTDSSSTVETGATEESVSEDMDEPVTEVEYITEEDTTDSTQAIFTSPEPVTLPRCKPKKPKPKPPTNCHKSKFGCCPDNYTSAIGPFSFGCDIAKTCNETEFGCCDDGVTPAENKRKRNCKLDCKASLFGCCEDGKTVAQGNNQEGCIKDCKETEFGCCLDGKTIKKGPKGKHCPKIPCSETIYGCCPDNKTPALGANFLNCSEINLENCKANFFGCCIDGTTAALGPNEEGCPDTPPCVRTEHGCCDDGVTGAHGPNKEGCCLSSRYGCCPDNINEALGPEFEGCTCASSPYGCCPDNITPARGPGPDCGCKFTEHGCCPDGVSPASGANHEGCACSTFQFGCCPDGVTVAKGVNDQGCGCQYTEFGCCPDNRTPKNSSESCGCESSQFGCCPDGVTHARGDEFESCEDVPIKPGDVCGLDKERGSCRNFTVRWFFDMEYGGCSRFWWGGCEGNLNKFATQDECKAVCVEPEGRDACYLPTVSGPCEGYYPSWHYDPLRDRCEQFIYSGCLGNNNRFGSRQECEHSCLMPEHVDDCDQPKTEGPCRGNYTRWYYDKSSEKCELFTYGGCKGNSNNFLTEKECHQRCGKDVRMRDVCFQSRSEGPCNEKLPRWYYDGGEQRCVPFYYSGCQGNSNRFSALDECEKTCPAALLAETHGCLDPLMQGDCASYTERYYFDRYEGKCKTFIYTGCGGNSNNFVHIDDCRSKCETVVPRPVATSEDQQFSQAHCFIPPPDPQSCSNSNSPPTIRWFYNSDDGVCYQFRYYCSNSSLNNFDTRQDCEDKCGSSQDFCNLPVVQGPCSGAFQQYYYERSTDECQLFDYSGCSGNGNRFDTVTQCEQRCKKHHEPVAPEPRVDDDEEAARREDDERRRAEEERRRYDEEERRRYEDEERRRIEEERRRYDEEQAKREHDTTLVTQDDICVLPVDQGPCRAAVKSWHFDVRERKCTEFLYGGCGGNANRFESQEMCERQCGEFRGQDVCNATPDPGPCTDSQSQKWYFNTLDNACAVFVYSGCEGNGNRFSSREECESVCHSRTEIVSGNDTITGAAICRLAPDSGPCVDGFKRWYYNAEDKTCIPFVFGGCAGNLNRFKSFDTCVNFCEKALGYTYAERSNPPNREQSPPRNSAEDPSRSNSVGDPARNYYYSDDGNNNNHYNAPCDCSYVKCPYGLKPHDPTESCDCECYDPCMNHICPESWRCSVDIQAGSYVPICRSARKPGSCPNLQQPRSHHSSICDNECSSDADCSGEMKCCVHGCGSSCVVPVFHESLPVSIVAKERVLNISEGSIIEMECTARGSPRPDILWVRVDSKEEGIFRKKCHHLIQTCQITGESGRYRIVEQPTATTSNSKLQVIGPTRDDSGEYSCIADSPSSPPRLRNHLSDDPRVEQPKRSLSSGGPFNPNDVDRELSSERYEQMRDYSLVIRLVSLRDLGAYTCQAYNGLGRAASWTITLLAYGPVQVQNVDDREYLVYVVDNQGITIPTRNISRVPTTTTTHTTTTLPPPIVEEETRPQETHDSGPNYLGKMLCPPCRGSLCVVQFCPVRVIVYVPAAHDDIDGENALLAGVRDPNPVRGGGLPPPSVHWYLNGVPIDLSQSSRVRYEPPELVIGESSSSDSGVYRCDAVNDYGASHSSISVSVEGMQLHPNCTDNSFFANCKLIVKANYCTNKYYARFCCKSCTLAGSFPRTGPPQKRLRRTSESLALRSTMKSSNLLEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWC0</accession>
    <name>A0A1D2MWC0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chorion peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09582</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000473">
        <property type="protein sequence ID" value="ODM97104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWC0"/>
    <dbReference type="STRING" id="48709.A0A1D2MWC0"/>
    <dbReference type="OMA" id="VYEDGWN"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09823">
        <property type="entry name" value="peroxinectin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.640.10:FF:000003">
        <property type="entry name" value="chorion peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904653" evidence="8">
        <location>
            <begin position="19"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="742" mass="84204" checksum="9F4D31A6B980C17B" modified="2016-11-30" version="1">MFKLSLLIVVLAVARTNAQFFFSPSQFSSGNLLGTHNTIVSSPSIPQSSFVSSPSQGITDIQDNSLDSVFSTVIAEATQYVDSTEGHRNHSSSYSFDHFGGGHQGGHGMGGHNYCKFTPLSEKIGRISNIHIRAFETLTKRYQMPKNQVLRTLNARLPNECYPEQRKPIACDTNARYRTIDGTCNNLRNPYWGASYTVFDRLVPAVYEDGWNEPRGAGKSLAGARLPNARIVSLSVHPDHISPDNRMTNMIPQVGQFLDHDMTLTPETDKHCCTTDARNMDCWSINIPSDDYFFSKLRNPSTCMAFTRSTAYCFPNLQGVREQFNVITAFVDASHVYASENGRTNLLRSHQGGRLRVNSQNPNFLPTVEEIQRTSGEKFEFMGTFYGGEERVNEMPALTVMHTLLFREHNRLADEIAARRPYWDDETIFQEARRLLIAQWQNVVYGEYLPVILGENTMVRYGLKLDDAQLYSEYNPSTNPTVFHAFADAAYRFGHTLINGLIRMMKGFQDVSSYRLRDAFFNHEQISMNGGQGYDFILNGLMQQNAQTYDPFITEEVTNFLLRERHQDHGGDLIARNLQRGRDHGLPSYNVYRQVCGLQGISNSWANRPSNIPQDVWQVLGSLYETPADIDLFTGGLAEMPLTGAVTGHTFNCLKALQFARVRQGDRFFFTHRGNPAPFSPEQLREIRKRTLGDIICDNSNIEMTTRNVFKIPSQDNAMVYCNDPNRNRINIEVFLYDRVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWX2</accession>
    <name>A0A1D2MWX2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">28S ribosomal protein S11, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000456">
        <property type="protein sequence ID" value="ODM97304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWX2"/>
    <dbReference type="STRING" id="48709.A0A1D2MWX2"/>
    <dbReference type="OMA" id="TPVSWNP"/>
    <dbReference type="OrthoDB" id="1654884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="211" mass="23140" checksum="B6C229B592FE19F4" modified="2016-11-30" version="1">MNFPTLFRQFRVLTTALPMRQSALEAGRISQQSCCFPVVENRRWKSEDRRVLIQSMPIKDMGTQGEKQLDVDLVNISKENVYPDADTPNMLFDGVRFADLPICHIKASKNNTIMQVTNSLGVLIAYRSCGMDGFKNTRKGTNIAAQTTAVAISGVAKGKGVTTVRVKVQGLGPGRMSAVKGLQMAGIKVASVTDNTPISFTPPRPRKARRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXN8</accession>
    <name>A0A1D2MXN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Talin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000408">
        <property type="protein sequence ID" value="ODM97813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXN8"/>
    <dbReference type="STRING" id="48709.A0A1D2MXN8"/>
    <dbReference type="OrthoDB" id="10262320at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005925">
        <property type="term" value="C:focal adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1410.10:FF:000001">
        <property type="entry name" value="Talin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035964">
        <property type="entry name" value="I/LWEQ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002558">
        <property type="entry name" value="ILWEQ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054082">
        <property type="entry name" value="Talin_IBS2B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19981:SF1">
        <property type="entry name" value="RHEA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19981">
        <property type="entry name" value="TALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01608">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21896">
        <property type="entry name" value="Talin_IBS2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00307">
        <property type="entry name" value="ILWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109885">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50945">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="I/LWEQ" evidence="5">
        <location>
            <begin position="172"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="452"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="687"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="335"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="506"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="531"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="559"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="577"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="604"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="698"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="708" mass="76530" checksum="EBDC90E440E18256" modified="2016-11-30" version="1">MVTNVTSLLKTVKSVEDEHTRGTRALEATIEAIAQEIRAFDSHDVPKGRIVSPEELVRATKPVTTATAKAVAAGTSCRQDDVIVAANMGRKAISDLLTLCKSAAYSVEGEMRDRALVAARQVAIHYRELLQYVLHAVLHPGSDVKPQLTQCSRDIAQSVTELVAVGQLMKGHEFEDPDDPTVIAENELLGAANSIDAAAKKLEKLRPRRSVKEADEDLNFDEMILEAAKSIAAATSALVKASAFAQRELVDTGRVNKKSMSDSDDGQWSEGLVSAAQMVAAATHSLVEAANSLVQGQATEEKLISSAKQVASSTAQLLVACKVKASAESDATRRLQAAGQAVKRATDNLVKAAQQALAQEEERQLVLNKRMVGSMAQEINARSDVLKIERQLEEARSKLAAIRKAKYQEKTGGLAGYTDESDVDIDTHETSRLDSLLESSAERITSAANTFNIMRKQPQQTPTSYPTTSTPLKPAVSPKPTAASIAERDRKFNNSSPSYSTISNDSSVGYSYPSQYQQPTPPPPQRSFQPVTQHSTFKSQTSTNGTSSQFPPPPPPPHAHQEEDLYARPRHPDQYYSASSAASTPTPTTPKKTFMKPSEFYSEAQRSPSGLSVQGQQTPGFTPPKGGFQVLPSSFGKTFGKVQEGGSSVQEEYSHYDSGPVRSEQVFETRGADGSISLRRIFTQQQSSSSQSVVSSSRKVFQQKDGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ56</accession>
    <name>A0A1D2MZ56_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein white</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_08391</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000366">
        <property type="protein sequence ID" value="ODM98292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ56"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ56"/>
    <dbReference type="OMA" id="FMLQFPA"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005284">
        <property type="entry name" value="Pigment_permease/Abcg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00955">
        <property type="entry name" value="3a01204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF129">
        <property type="entry name" value="PROTEIN WHITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0608">Pigment</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="579"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="636"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="72"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM98292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="666" mass="74088" checksum="452168650362EAF4" modified="2016-11-30" version="1">MSVKRQTVQGQVADDNPGHDNQGFDYSQSDLPNAANSGRRFTSTKSGSIHLNQVYYTWNDINAVAKVEKESFKLPCFGKKSDIPPKEPKQILKNVSGIARAGEILAIMGASGAGKTSLLNILTFRNTSSLNISGTRMVNGVPIDAVQLTLISAYIQQDDIFIGTLTPREHLRFQALLRMDKEFSYKERMRKVDEVIKEMGLTGCADTIIGIPGRIKGLSGGQQKRLSVASEVLTDPQLLICDEPTTGLDSFMAANLVKTLKSLANKGKTIICTIHQPASDTFAMFDKLLLMSEGRVAYYGDAKKAPTYFSSIGYPCPETYNPADFYIHTLAIRVDNAEECLQRSKAICDKYDESDNAKALKATAFSKDDELSKALKEVAKKRQKSPYKASWFAQFRACFWRSSITVRKDPLVLKVQLIQTIFLSLVIGLIYFGQENDQESIQNISGCIFMIIANLTFSSIFPVTNVFWSELPVFMREHFNGMYRTDTYYLAKTFAELPVYLILPAIFISISYWMVGLNDDIDRFFIAVGTAVLVANVGSSFGYMASTVTPSFETTMALAPVMITPFMLFGGSFLNKDSIPVYFIWLKYLSWFLYGNEALSINQWKGIKNITCEEGLACIEDGNQVLDSLSFKEDNFGMSLACLGGLIVVTRLISYGGLVMKSRRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZZ4</accession>
    <name>A0A1D2MZZ4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphosphoinositol-polyphosphate diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08109</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.</text>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DIPP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000341">
        <property type="protein sequence ID" value="ODM98592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MZZ4"/>
    <dbReference type="OrthoDB" id="2011998at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034431">
        <property type="term" value="F:bis(5'-adenosyl)-hexaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034432">
        <property type="term" value="F:bis(5'-adenosyl)-pentaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008486">
        <property type="term" value="F:diphosphoinositol-polyphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901911">
        <property type="term" value="P:adenosine 5'-(hexahydrogen pentaphosphate) catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901909">
        <property type="term" value="P:diadenosine hexaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901907">
        <property type="term" value="P:diadenosine pentaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071543">
        <property type="term" value="P:diphosphoinositol polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04666">
        <property type="entry name" value="NUDIX_DIPP2_like_Nudt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000002">
        <property type="entry name" value="diphosphoinositol polyphosphate phosphohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047198">
        <property type="entry name" value="DDP-like_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629">
        <property type="entry name" value="DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629:SF0">
        <property type="entry name" value="DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="11">
        <location>
            <begin position="142"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="285" mass="32029" checksum="0F788C4680AD004E" modified="2016-11-30" version="1">MAICCGVCSLGGDYLSPITTCCSSYCCSGVENFNLNFKRRAPNEGSKPAGCFNEGSLEFNSLARVNTDETIMITRNCFTNYCVTDHHHCDEGRNEDVHESLNSTDSTAGRVTYSTFQLQSAKKIKMVKEKPNSTRIYDTEGYRQRAACICVKDETESEILLVTSSSHTDQWIVPGGGLEPDETSEVAALREVIEEAGVHGNIERSLGTFQNEERKHRTAVYVLIVTEELPEWEDSKAIGRKRKWFTFEEAMKQLAADKPVQMDYLEHLRPHKKRNHQTDNGTAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N041</accession>
    <name>A0A1D2N041_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transforming growth factor-beta receptor-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000341">
        <property type="protein sequence ID" value="ODM98571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N041"/>
    <dbReference type="STRING" id="48709.A0A1D2N041"/>
    <dbReference type="OMA" id="MFVTSEG"/>
    <dbReference type="OrthoDB" id="8169718at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="CHCR" evidence="1">
        <location>
            <begin position="368"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="638" mass="72961" checksum="95A5CC3CDBD9F255" modified="2016-11-30" version="1">MNAQKKNVAELCQFDPKDVNPKIVNAGKEEFLLIGPGGLGVFTSSSGISERPPIIWHDKVNEIAVDGLNVVAAGNDVIYVNSLHDPTTSNVIPFPGVKCLALTEGKLYVGTARSLYRFTPISVDEQVESLINAEKIDQALNLLELAHVKDEKREYLRRRILRKAVFLRMHALELTSCMEAIRESHIDLREIISLFPTILPSNTVFTRSLPSLHEFIDVNQMVAGDPHKARTLASFLLAVLTTHETMPDSKDLSTSAIKLAAKYDKSQYIIILDHVSCMEIDYDDCFEWMEDYKYFDCAALLYKAKGDVRKALDLWVDLLSNTKKCEDPDEFEGVDVVIETLLSSVNANLIWEYYDKLLKYDPIKAVEVFTKRELSPSFQPLNVAEKLSSNRPICMLYLRHCIFEKKLDDEDLHTYLATLYIDEIVQETNASDVERLRTEFRQLLISSDSLKVQFLIGRLQKTQLRLELAILHGKAGDHDPALKVIVEELHDYNFASEYCIKISDSSQREKAFMSLLKIYLNAKDKPEIIEACMHLLTNHAEEFDFSIVLPLLPDEWNIRSLSDLLHRVLRTHLHRQRRVELLKGLSERIDKDYRLEADANNQGYILDEDSVCGLCHRKLDNLEPVFYNKGFIVHSKCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N048</accession>
    <name>A0A1D2N048_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Syntaxin-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000366">
        <property type="protein sequence ID" value="ODM98285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N048"/>
    <dbReference type="STRING" id="48709.A0A1D2N048"/>
    <dbReference type="OMA" id="RYKHIAY"/>
    <dbReference type="OrthoDB" id="2228at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="587" mass="67521" checksum="189EB6BFC5CCBC93" modified="2016-11-30" version="1">MTSLKTVTKQLIINDVLRGTASNNDNKNSNDLNPDWRVLILDKQATTVLTSCCNMQGITTEGISMVEDLYKKRQPFPSLEAVYILQPIEKSLNCLLADLNSDQTMYKAFHIFFLEICPMESFDTLCEVKHKRRIKTLKEINFSFIPAESNVYLLDAEESMKFYYNPQQNDDGKTLMELQRLAERLATVCATLGEFPSIRYRAGYPKNVVFAKTLERKLQEYKTSDQAMGEGPEKLRSQLIILDRGFDCVSPVVHELTFQAMIHDLLPVKDNIYTIQSQNGRTKEILLDDNDESWKSLKNTHIAEVMQKVPEEYKKFLESKNIHSNKTNIKDLQLMIKKMPQYQKQLTMLDTQINMAADCNSAFKKIEKLCEVEQDLATTVDSDGEKLRDPMSQINPIILDFDVFTEYDKLRVIILYILFKNGVAQSSLQKLLQHANVSSDMHSIVTNLSLLGQNVISGEGNSGNQIPRKNRENEGVRYKLSRWIPVIKDVMEYALEDNLDKRLFPFQLNRLSETGYRVPTSTRYGWHNQGSLPRNRPKIIIFVMGGVTYSEIRSAYEVNSQQNDYEVIIGSTHIITPQRFLENLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0N0</accession>
    <name>A0A1D2N0N0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Apoptotic chromatin condensation inducer in the nucleus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000319">
        <property type="protein sequence ID" value="ODM98829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0N0"/>
    <dbReference type="STRING" id="48709.A0A1D2N0N0"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061574">
        <property type="term" value="C:ASAP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12432">
        <property type="entry name" value="RRM_ACINU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034257">
        <property type="entry name" value="Acinus_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052793">
        <property type="entry name" value="EJC-associated_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032552">
        <property type="entry name" value="RSB_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46589">
        <property type="entry name" value="APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46589:SF1">
        <property type="entry name" value="APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16294">
        <property type="entry name" value="RSB_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="442" mass="50685" checksum="61925A25AE060FDB" modified="2016-11-30" version="1" fragment="single">SPVREKSPAPEKLEVVKKDNDVNGESTEVTPEEKPVQVGDKKDESTKSPRYKSSQKETYTKYDLAGEEALDYGEEEDDEDRNEHDPQEFSWTRRSLRLKNKAATSASTCKWKFEEESKLLVVKSELLNKYYEDIKLVPLEQLKLEEKTLPGSDTKVETSRKPSISQEPEQEEPLPTRTVENIPTVKRTVSIVSTTKTQIEQLDDAEKQLTPPRNPPSSVLLITNLVRPFTLPQLKEMLQRTGNLVDIWVDKIKSKCIAKFDSQEEAFETRAALHGVCWPSSNPKSLHVDYTTLDNLDDHKAKEGADQNSVSEKPMSAQPVPVREWDVGKKAEPKSPRSRKRSRSRSNSRDRAKRSRRSSSPGRRRHSRSPGHADRRGRGVEGKEPEPMGKALDELFRKTVATPSIYWLPLTPEQIAEKEELRRKRMLERERRLAELSKMRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2R1</accession>
    <name>A0A1D2N2R1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07099</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000270">
        <property type="protein sequence ID" value="ODM99577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2R1"/>
    <dbReference type="STRING" id="48709.A0A1D2N2R1"/>
    <dbReference type="OrthoDB" id="6277246at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="41282" checksum="08F1499DF4506DE9" modified="2016-11-30" version="1">MNGDYYIMLQGTQNTIQGRYDNLGNLASPPIQAHRTTDSTIGQTQQQQQQVVYAATPAAQGTQQWNFTRTTGEVNVAQPQTTPSTPTPTKSKRTLTLTQTLPLCLEGSSQSHSTPKASKSTPADKQVHYCRWEGCKKSFRRLKLLENHERMAHSQQGDDGMGCSTVGCDKKFNDKKQLQHHESRCELKPHRCSWEGCDKTFRTSKLLHGHISAVHRRIGRNTYKCSIPGCQQAYPDSTKLKTHEVRCKFRYETLADIKMETDAANAALLVAANAVGDVTSVPTVTADVAAVSSANNMTASSVPGAEDAMNMSMSNSSIEGNKQPASTVDLSFMVKNDENTVVRFCPLGQWVSSGWLFGGYTWSTTVQYDKLLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2R6</accession>
    <name>A0A1D2N2R6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase II subunit GRINL1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000274">
        <property type="protein sequence ID" value="ODM99521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2R6"/>
    <dbReference type="STRING" id="48709.A0A1D2N2R6"/>
    <dbReference type="OrthoDB" id="1935146at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003711">
        <property type="term" value="F:transcription elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026213">
        <property type="entry name" value="GRINL1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15328">
        <property type="entry name" value="GCOM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="324" mass="36062" checksum="7D38045AD7DD1D97" modified="2016-11-30" version="1">MDNQPTSALEEQLARQKGILSNSKLIQKLPDKGAKLRDSVAKIEEELVKRRSEAERSQRLEIVDVGKLEWSLRTTTLTNSPSGNDPPSKTDVVLDSDDDEEPNSQSESQNPLQIIATSQITQREPKPTFLSTPGGTYGKEGEMDLYVFKLIENDVKTAAAHSSHPKFLPGKSLKSSKGEGSSSPMETSESPANSVSSNSTKPPKWDECLLPQAYNHRTATLLTMEETVKLSCDQYKKVQLQKLEATTKEKKVYAYDRLREQGLLNEYSVEMQTTRPVRTDANDDEFEEDLEDDEITEESESGESDDEASNDLSNLVNASLKLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2R9</accession>
    <name>A0A1D2N2R9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Synaptotagmin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07127</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000271">
        <property type="protein sequence ID" value="ODM99552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N2R9"/>
    <dbReference type="OMA" id="ESCRNER"/>
    <dbReference type="OrthoDB" id="195679at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042043">
        <property type="term" value="F:neurexin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08521">
        <property type="entry name" value="C2A_SLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000006">
        <property type="entry name" value="Synaptotagmin-like 5, isoform CRA_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45716">
        <property type="entry name" value="BITESIZE, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45716:SF2">
        <property type="entry name" value="BITESIZE, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="5">
        <location>
            <begin position="3372"/>
            <end position="3494"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="5">
        <location>
            <begin position="3507"/>
            <end position="3627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="284"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="394"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="500"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="586"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="657"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="771"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="914"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1047"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1215"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1295"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1338"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1434"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1474"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1548"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1665"/>
            <end position="1757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1772"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1909"/>
            <end position="1961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1985"/>
            <end position="2032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2050"/>
            <end position="2213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2265"/>
            <end position="2698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2732"/>
            <end position="2767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2786"/>
            <end position="2817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2847"/>
            <end position="2875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2920"/>
            <end position="2995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3210"/>
            <end position="3264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="555"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="618"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="667"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="777"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="938"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="959"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1056"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1105"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1135"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1215"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1228"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1299"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1338"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1357"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1445"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1495"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1509"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1586"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1603"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1665"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1723"/>
            <end position="1738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1827"/>
            <end position="1860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1909"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1932"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1942"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1987"/>
            <end position="1998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2000"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2017"/>
            <end position="2027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2066"/>
            <end position="2090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2091"/>
            <end position="2104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2290"/>
            <end position="2313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2322"/>
            <end position="2341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="2367"/>
            <end position="2380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2383"/>
            <end position="2393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2402"/>
            <end position="2417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2492"/>
            <end position="2504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2530"/>
            <end position="2543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2588"/>
            <end position="2627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2649"/>
            <end position="2659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2742"/>
            <end position="2767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2799"/>
            <end position="2808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2863"/>
            <end position="2874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2929"/>
            <end position="2951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2980"/>
            <end position="2992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3213"/>
            <end position="3223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3234"/>
            <end position="3243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="3634" mass="398239" checksum="6E7E05268058703B" modified="2016-11-30" version="1">MSRCVLNEQEMSSHLSSLVPCGVLIFCADNIVLCKVLNIKRHRSFQTTLHPYTPSQANPTSPAASINFIEETFWDYYDYEIENSSSDPSSTPRNPRKLPGTTNTVPTEIKSPRFKLRPSDTKRTIEGSTKPSTLVTFRTDSNRSSCERSLGETMDYDCSLRTNQFSSLSDTEINETGKDPRKSGASPYSVNSTGYRRHSNVETNPRSTYHYATISSTTNPYLPASEYVYRRRHDEMMTEAPPKPERKYRNSKRSVSLNAYDGRRLFSPLRTYCVLMKENIEPGDKLENDSHVNFTTLTPLNNPRHESGSATKSKSNFESGAAAAAASSSAIHKSSASPISLSFSTISSSPHKFNSLPRERYIRIEREDGNGSMNAEKYSSLKYPSKKSEVLLGKSRDIQHQQQQISSSSREKNVTRVPIVQDDDNDQQQRFSSIRNFSTASIPPKNKIERSQSYKEISSSSSRPYPYYHQYHPHPANNMEPQNIQFTTNNNNTAENIRHRHNHHHPDKSSSTADLNYMPTGTATLPNFRNRGRSSKGQFVSSSSASVWNDKKDQTSSGSRPNNFFQSDFGDDESDVVIENFIKTHSSTNNASNSNTLPKRKYPPSSTHISNNCNTPQRDNDSHRSYGERDSSMKSDLKATFQQDSLGDNYLRQCSTFPRGGIRTRASKSSENVDDNNTTTTKQTENLPNYNKSRNSSFDFPKGYSNVEKIDVFFHPSPSTGSAAPFDVPKQSHQLPERVVPIKLAAGPGSSATLPHPYIRRNKQMTVAPPLEKPSENNPTTIAAPNIITPTKSPDSGPSISEVEMEIERDIFYQKTRSLDRIRPSSKSKLKSVLSIGRSSSNANAADRVDAANAHQHYPMEIDYSDSQPYNKGRHHESLFSIDQVDRKYANSSKSIHATGTSTSSDQHLLEPQQIHHSHSVSAPIPSPRLKRKGKLQPTPSFESATTSALCSPKINGDEMSSTSKLVGPGTNNGFGSKKQPFTSSSSGVGRLTEPDIRNDLDILRKTNGAASSNPISLGNPSLNATSSTLPTSKLSLVKETSIHADNHHQHHHHQTASIGMSNGDGNNKSEKSSVTNYISQPSTPASVTPNYSNVDGPGVNFMISNSMSSSSPQFDSQPQQHQNPPFASAPKYFSETKTKAAPDSQKKSALATADASSKLNKAVRFEPHVIKMEMELEHRKLLQQQQQINQLSGVSAQSSSATSATAQLVNSNVNNPSGNANGPKSGTHIHRHGHGTSHNGNKARAHHVHAYLPVLYHQSYHQQQHKYRKGATVGGKNKKIKGFVARAIAKVKGKKAVDSSTTVGKQDKGNSSSSTSNEEFLQYYAPSSSVITYISPQPQAHHQQPPVQQSLEESKSTALQENSPHQYPKPVVPSITVSLTSATEEVAESAPVSGEVNTSSRGILVKTKSESVEHANNSRKPIAKYVITPGGRLKKNLHKGANNSKASLSSPKPSGGGGATRRMDAYLTENMDEGQLSFGPSESDERHPQGLPIPSSSFTLQTDQITPSSTSSSSSSFTSNLQESYELFHNQTLPDRIHQLVSEVEAAAEDNERCDSLDEDEDSDNNNIIGIDDIDDPSTFKSFDESDFDEDEDADFVFYPTPRSTKPPHNQSSSSAKHNIIDTDHPHHHHQLNKAITSSIVTSSTDLGSSYSYAPFGSNINETTTKGNVNNHQYSDSTSDSRAHNAMKKGKSNSEPKMVVGIPTYRSPNSRRPLINSHHGKSQASIPNANPTVSSAAKENVKHKFKEPHPTQQLGANETINVQNNAISAEEHGGAAASSMYKDSSRVGGGIKQQQQSEDVRLLSRHHHAQQAGKTLQQHHKNQNQVDEKSQPQPLNDKRSHERIREHKRNVDDHVHDEDTLQTTTTMNVPTVAAAESCRNERVENDTNPHDATGFLKISTTEKNSTEYGATGAHNNSNRTQQSIPSFGKRNSSDHDEGRLTDLTSTITRSTTTTANTTNNGQQLAVLDQKLEDLKDAPESYIVDGGEQKEYEGKEVGELNSSGESSLPSWAKTKNHNSVTTSNKNCQHQKDKERLARLELVVKKVQTSSADFEIPRNIDNEVDSGPSSSPPQLFEQQPNSLETHCGNDQSFLSESEVSSGKSPSPSPRFKSRNKRGNGSGAKLIPKFKTGAKVAGGGGARGCDTGSEEEVESNSKSKPSHLLNAHTTQSCFGRQRETTGENSEEYPLFSPDSGPFGMSMLPPQHPAAASSTNVSDANNFIGKFKSRVLLNSDDLEDDEEIAQHVADAIHNNKVNNRTTPAKRNITTVEISGDVGIVSSGGGGGDDTHQNVVNSSGGVGGSSSPPNSAPSISGRQAPLLSNDHLQSSGLSLISQPTSINLHDSSSDEDSLEVEKPIEPQIRTKLVNNDDEDNLIGIEELEVGSSVSANESSGDNDTEKTTTSDDNSSDWQSESTNTVIFRGNPSVKKNSDTDIDPCNQPPSLYGHNSYLDPEIQINNITIGGSDYDDYHPDDDDDHTGNDDVTPNPTPEPPSNSNSNNSSSSKSVNVGYKATKVNKVSTDLIIGIKKSSADNVESGSAQVPDSNQEHLEMVMQSDKQGTRLYVPNNSNKSPHQRRESPEGQEQEVPDQSEKDKSPTNKPPISEKPRPKSADATDMKMEEGDSGEGKPKKNVKSTSSTKGSISKERIVQSVLSQIPSRSSPDGADADRDATPEPEVESPTPPGVIDSFDVTSDEDSWVEEILFEDEDDTSFEEAVKKLPPPLDLTLHTIVEESCEESEAENSGNFYQPSTSGIGGSQKNHSLSQSDSNANELEKYFNFGIYTDHNSSAKNSLPNEESEFSDTFSESSFSLQEEDFDNGTEGLLDPAELASSRLEKYFYNLGVPQSMMNPMGGSMNQHHHHADSDSVGSESDSDNSVLEKRKKVLKHHRRSADFEEEFGDKVSDEEDSFVFGQDGFDTIKKTARKTKKSGSEGSISNDSTLQAGNLSSNSNGVDNLDGSGDLSSVFENKSPKTLKKSDSSDSSKTSTSPSNNDKPVIKVNRSNSFTWSSDEEVNIMMSKLRQLIKNLIKSKAEAGSAQSTESQASTSETGVSKDKQLVYLENELIRLMKTDNLKNIVEYLSSEESDVDDVYKFIKVVNSSGSTPVDLSDLGDLGDLDIDDPNLLENLQSTMQLQGEGGGATPGSPKSSPALLAKVMHHIGNRLNMWMKDEANLEDDNNDDNVTIKCAPSVSSDLNEDRFSWKGSFESALAAKRQSVGSTDSISSSDYGPDKSMLRSSSLHHLTTSQPIEENREEEEPSSSLPRMTTLCNSLPRLNQPANAAISRAHSLVMTAKSEQPGTETYPISISGPVKSARYRPPGFQPSMKAKRIDTEEKASPAILSQSTPVLTQDPAMLKNRSDSMGSIFHDVKPLISVKGQVEFGLQYNYKLACLEVKVVGCRDVAAADSKRNRSDPYVKAYLLPDKSKAGKRKTKTKKNTLSPVFDEILKFPLTLSDLQNRTLWLSVWHSDMFGKNEFLGEVLVNLKDRVFDDPNPGWWDLQEMSGQMEDMPKGDVVIALKWQPKTDSTGNLSVLVKEAKNLVPVKNGSPSTFVKCALLSDKTRKQKTSICRRNFNPIWNQTLLFEDVDDDGVEITIWNHDLLASHDLIGTVRLEYDNPLWDSMISRPSFWVEGGHKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N382</accession>
    <name>A0A1D2N382_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sarcoplasmic calcium-binding proteins I, III, and IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000261">
        <property type="protein sequence ID" value="ODM99700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N382"/>
    <dbReference type="STRING" id="48709.A0A1D2N382"/>
    <dbReference type="OMA" id="WGETHEK"/>
    <dbReference type="OrthoDB" id="9974725at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="6"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="24099" checksum="AD590A345B7D5E42" modified="2016-11-30" version="1">MAMSDFRLAKLLYVFERFFDTDKSGTIEKGDFVLAVQQLCKIRGWPESDPKYESTQKKFMTMWEVLRKRCYKEDDERISPEEFCQLWRNPDKIEEWERTYMDIMFDLQDTSGDNVIDEDEFVGVCESYGINSAEARAAFQTFSHRGRVNVDKKYYEKMWRGILRSATQPKWVTTSTISYIQLSASSTKNSTSATATIPDTTTQKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N468</accession>
    <name>A0A1D2N468_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000234">
        <property type="protein sequence ID" value="ODN00077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N468"/>
    <dbReference type="OrthoDB" id="8283431at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="635" mass="73633" checksum="EED182767AC47EA1" modified="2016-11-30" version="1">MYRFKMTDEEFSGMDLEDFSEEDELQEESMISLKRQLIASEEIIRNLRLSNASQEQTIHNLVSAIEKLRSLHLEERRVLEGIKIPNVLSSFRISDSSNSKVVQPAIDYSQHPLLNHIIVSNIMQRLPLNDVIKCRLVCQSWWGKANEELRKRKLIGINYRNIENLSKFAKLLETSGDIPFAKFRFGLFVVNTHRVAVEDFFSVCGPVITHIALCFANQFCEISLEELRDLFLLRVPNLEKLDVERLPLKLTKELSLFPPGTKVPQLRKLKHLKIWDNMASDNRMDSTYSVGLIHDLISMAPNLSKLSVYTECQHLVAAALKSLEEKRIELRELRLESISEENLLYLTRLRFPLKMLRIEYFDTLTAPESVKSLLTTLSFTLEELHFSDYRVMNHAENLVVAFPRMARLRVLKFRRPWNDRRLLFYPLSFKEQLPCLKKISFQHEQGSPPYCIHSYNDFVNPETTGPAETVEELEITHELDSVIMFRKLPESFPKLKILKSTDSSNEIIRAIWEFLPNLQELYLTLSISNRNIDSVITGIPVEVYRQICKENLYSRVDGNVLEIIRTDPSICNLKKLSKLVIEGHQINRVTDFACSFALIFLKALTSLTITDADITEDCRDLMKIHLNLVHLEILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6A9</accession>
    <name>A0A1D2N6A9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000185">
        <property type="protein sequence ID" value="ODN00809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6A9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="24" mass="2916" checksum="7D3CF451DFADBDC3" modified="2016-11-30" version="1" fragment="single">MLILIRGVHQIKRMILFLKCYVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6U4</accession>
    <name>A0A1D2N6U4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_05738</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.</text>
    </comment>
    <comment type="subunit">
        <text evidence="21">Interacts with TIMP1 and ITGB1 and recruits TIMP1 to ITGB1. Interacts with CD9. Identified in a complex with CD9 and ITGB3. Interacts with PMEL. Interacts with KDR/VEGFR2; identified in a complex with ITGB1 and KDR/VEGFR2 and is required to recruit KDR to ITGB1 complexes. Interacts with SYT7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell surface</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Lysosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Melanosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Membrane</location>
            <topology evidence="22">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 22">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000180">
        <property type="protein sequence ID" value="ODN00952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6U4"/>
    <dbReference type="STRING" id="48709.A0A1D2N6U4"/>
    <dbReference type="OMA" id="DSCCKTR"/>
    <dbReference type="OrthoDB" id="9993879at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03155">
        <property type="entry name" value="CD151_like_LEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1450.10:FF:000019">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000301">
        <property type="entry name" value="Tetraspanin_animals"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF544">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002419">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0967">Endosome</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="19" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="18" id="KW-0458">Lysosome</keyword>
    <keyword evidence="15 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0964">Secreted</keyword>
    <keyword evidence="11 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00043922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00046382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU361218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODN00952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="259" mass="29221" checksum="C1F3D1EF224A4C2F" modified="2016-11-30" version="1">MMSNRKYEKSEGWCSKSLLRNYLYIFNFFFLCGAITVLLIAVWSVLAEHGFISLLSDVSYPWTSYLLLAAGALGLIAAVFGCCGIAKSDRCYLFVYILLLLLIFLLEVMAGSLAYIYREQAYQELQTRLNVTFIENYGKEPVDDAPKTRAIDEMQREFQCCGANSFEDWTHSRWLLDGLAKENKVPDSCCKTEGPGCGVRDHPSNIYYTGCIHKLSDTVRNHLGYLTISGLGLCILQIIGVIFSTCLYIKLKEVDITDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N710</accession>
    <name>A0A1D2N710_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mucin-5AC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N710"/>
    <dbReference type="STRING" id="48709.A0A1D2N710"/>
    <dbReference type="OMA" id="GFHTAHR"/>
    <dbReference type="OrthoDB" id="10690625at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="733"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="760"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="863"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="873"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="980"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1050" mass="112492" checksum="9BEC83A1FB7715B7" modified="2016-11-30" version="1">MVVRYSQVMKVVKASIRTKTCSNNGLRNEITIQSINEQPDATTNPAFQEEDLYEATTLPEEVPVETTTPKEQSKMVVNIITSAPRQSDKSTTSTAPPPTTTQAATTEAATTTTTSASTTTSEIPTTTTVGSPVFSSPKSAPAVDDKENLVADATQRAASSLHGFADSQAKLQAAESSQPARVNVRPAQNGKEYEYEYIYYYYDDDDENSTEKHAEPSVKAVGQNPEVIKQGSRGSTTLTPSTNAASSASSTTTVKTSTTTLRPQVSSDADFEYEDDAALDEEQVPEVPEIQKSTPGATRTTEAPISKGLTSAEKLSNQNPINQLDRSRGPKILQSAEKFDDAAADYKLEAEASQEEEAHVRSKGQPLRQAATSSEEDEQTADAPEDEVSREPSTSAPASTSGLDISQMSTLAKTHKDSVNVPIVIKQSSLLKAVPVSQLQSQSELAPERPSTSPFTTPSTTTTTTTVEAASEVVPSVRPSPPRLRGQRPRGNNATPRPTPASTPAPEQPAEEKPQQSIRRPTLRDSPRRIQSRRPVKESPEEIPEQQPAASPIIETHARPLPIRPRFPPRTGNHVTTTTAAPAEIVSEIPAAAVTPSAAELNSLEDKRTKDTHVRAKSANDLYAFTRLQQAISSRAPSRVQPKLVAGFVNSAEVTTDAMTSSEVTTVSSFGGQSSETVVDDAPSTTSTTTTTTTTTEAAQLDKFGRQRGRFGAGRTRRPGASATGGDGPQRASTTTTESPSTTVRGRFNGRRRSSTTTVAPEEAGQQQSSSAPAESPKPKLPARNRFASRNRGSTTETPVTTVEEQKTSEVEKPSTPAVTQPARRRPEQPGRNRFAIGGRARPNPAAGNNPVRIRGGGRLRDTTTTTTTTEATPEETQPDEEQPADAEQSPTIQSEHIEPAQNVPAPEAPAPVRGVLGRLKNRPKLVVTTTITPEAVHLDRKPGRLNGILNRRKNLGQLTAAAHVKEEVRETTSEVAEESDNHAQEVEDDHKGVVVQISSSVTESEEVNEAAGEVVEPSSTTTPGSILNRLKSQRKPGSLFRKKPDPHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7R3</accession>
    <name>A0A1D2N7R3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nesprin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05368</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000160">
        <property type="protein sequence ID" value="ODN01313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N7R3"/>
    <dbReference type="OMA" id="DNHQTQI"/>
    <dbReference type="OrthoDB" id="6538186at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034993">
        <property type="term" value="C:meiotic nuclear membrane microtubule tethering complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21243">
        <property type="entry name" value="CH_SYNE1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000033">
        <property type="entry name" value="nesprin-1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="29"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047291">
        <property type="entry name" value="CH_SYNE1_rpt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052403">
        <property type="entry name" value="LINC-complex_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057057">
        <property type="entry name" value="Spectrin_SYNE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47535">
        <property type="entry name" value="MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47535:SF1">
        <property type="entry name" value="NESPRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25034">
        <property type="entry name" value="Spectrin_SYNE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="44"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="8">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="8">
        <location>
            <begin position="129"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="4830"/>
            <end position="4850"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1410"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1512"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1618"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1871"/>
            <end position="1953"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3404"/>
            <end position="3431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3474"/>
            <end position="3501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3757"/>
            <end position="3787"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3818"/>
            <end position="3883"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="4397"/>
            <end position="4475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="4684"/>
            <end position="4747"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="4993"/>
            <end position="5020"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="5215"/>
            <end position="5246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="5700"/>
            <end position="5782"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="6216"/>
            <end position="6243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="6393"/>
            <end position="6435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="6503"/>
            <end position="6530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="6747"/>
            <end position="6774"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="7021"/>
            <end position="7065"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="7386"/>
            <end position="7413"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="7494"/>
            <end position="7521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="7624"/>
            <end position="7651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="4830"/>
            <end position="4841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="7674" mass="878504" checksum="13BE1C425C359B70" modified="2016-11-30" version="1">[encoded data, 7674 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8B0</accession>
    <name>A0A1D2N8B0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Calcium-binding mitochondrial carrier protein Aralar1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_05197</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000149">
        <property type="protein sequence ID" value="ODN01499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8B0"/>
    <dbReference type="OMA" id="AEAQRQX"/>
    <dbReference type="OrthoDB" id="2161at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015183">
        <property type="term" value="F:L-aspartate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043490">
        <property type="term" value="P:malate-aspartate shuttle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000416">
        <property type="entry name" value="Aralar1, isoform F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000004">
        <property type="entry name" value="Calcium-binding mitochondrial carrier protein Aralar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="91"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="330"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="429"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="521"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN01499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="673" mass="75939" checksum="9A45313796597F13" modified="2016-11-30" version="1">MNAFFKGKSERRIKRATREDLYAVFLKYASVEVDGLHYITSEDFIRKFLGLHQNDDYDPNSVKLLAGIVDASKDGHISFPEFMAFEGLLTVPDALYFIAFRLFDVNGNRLVSFDEFAEIISYTTLQQQIPFNLESPFSQLYFGKDRSRFIKYSEFSQFLHDFHEEYAIEAFRKFDVDGSGTISSDDFYTIMTTIRTHLLTEDVASNLKEVAQRISGCDQVSLPIFAAFNSVLNSIELLKRVYLTASDEEESKEISREEFLCATQFMNIGTPIEVDILFHLNELINKSPTLILADFQAIAPEQYYTKVNKRILDIKAVQSPEQRDWVTELLESLYRFTLGSIAGAIEAVGAYPMDLIKSRMQIQRPGVLFEEPLYKSTWHCFKKTLKTEGVPGLYRGMLAQIIGTSMGKAMKLSMNDFIRDKLMNRKGQVPLWGEFFAGAVAGACNVFVIQPLEAIKIRVQTVGELFPKAKLRMVAVIKQLGFKGLYRGTAACMWRDVPFSALFFPTYAHAKVYLQDADGYNTPISVLAAGLVAAIPGAPISMPFDVIKTRLQVDPRPGQKAYAGIVDAASRIIKEEGIRKFWQGTRVIKPSQFGITLLLYEVLQRYFYIDFAGTRPTGSEATVRITSVDQIKSENPDHIGGFALAVPILSGIESKFGLVFPKFKTRITKPSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8M8</accession>
    <name>A0A1D2N8M8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G-protein coupled receptor Mth2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05093</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8M8"/>
    <dbReference type="STRING" id="48709.A0A1D2N8M8"/>
    <dbReference type="OMA" id="WVIFDIV"/>
    <dbReference type="OrthoDB" id="6082634at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15039">
        <property type="entry name" value="7tmB3_Methuselah-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052808">
        <property type="entry name" value="GPCR_Mth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905211" evidence="6">
        <location>
            <begin position="26"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="594"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="345"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="657" mass="75843" checksum="D41A64B078767873" modified="2016-11-30" version="1">MSLRIDKSLLLVAFYLCVHFQYCLPQSSSSISTSSNYDVYKCTGRLHDTRETTVTIPGQFVSDNATKTFPLKRKELNCKKGRFKVLFQLPHQNEDSSSLESPGSVKVLRTDLKTRKTVSYADPQIKIMSDLPYLRISNEFFHPNEYCFDQIDSNELSLFVCYPECYGQRPCVTKCCGQDEVWDVNNARCKRVLDSAILSSKSVPDNNTTVNSSSSVNNGTKPHYWSPWLFSRSVDKCVKRVTAYHRQQIDIHIQQRLPSCDPSTYVQIPLRKIHNHAVQRFRVLWTGQVIMRDKRGNWSEFSQGRYCVDGMTNFGHGDVYTGAFEDQILLVCPDQAPLTVQKKPIPLRYAVMLLGSAAILFLTALISTLMWDRQNVYEWTVSCEVISMFFMILLVGIAHTIARKPEKSDFGSIHCVFIGAASHFFWLSTFCWLFIINFEIWWNFRNLVQLRQSRKWFRFSVYMLVGWGCPLVMVVVGLFLDRVWGLQNEDLDCTNVIVPNYGQTNCYISKQAQGPYLFYPIGLVLVINLLFYLLTVCKMWGYQKKSQAIIQYRSKGQTQPILIFAKLFIVMGVSWIFEIISWGTTSSDVDRIPLYWVIFDIVTLFQAVCIFVIFIWKKETLSRLWYKYPCFQPLLAPLSKLPGCGLLPNERDRLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8T9</accession>
    <name>A0A1D2N8T9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein MON2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05012</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MON2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000144">
        <property type="protein sequence ID" value="ODN01672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N8T9"/>
    <dbReference type="OMA" id="AWRLCLN"/>
    <dbReference type="OrthoDB" id="294853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF333">
        <property type="entry name" value="PROTEIN MON2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="8">
        <location>
            <begin position="13"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="6">
        <location>
            <begin position="193"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HDS" evidence="5">
        <location>
            <begin position="834"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="7">
        <location>
            <begin position="914"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="7">
        <location>
            <begin position="1152"/>
            <end position="1568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1575" mass="174968" checksum="2EE72D318EEF061C" modified="2016-11-30" version="1">MATDNSGSSPTNEKLIFALQNDLKTLSLETKKKHGFVKDACEEAIAKIRGAQASPNCMAYITNQALYPVIQGCDTKDPKIVKLCLHSIQKLITGGYVDVKGARSIYETVVVLLENGIEEIKVLQIVTLLLTTNNIVKGDILAKCLVLCFRLHCSKDITTAHAAGATVRQLVSLVFERIDKDSPVTDVELSPEATDAYSLFQDLIFLVNGEKPVWLVGISEMFRSFGLELLETVLYRFPFVFVKYDKFGLLLKERVCAMVIKLFSPNAKFKATQAQQGQTAAGDLLLDKPFYPTSVRLLRIVDILINKYYTLLVTECEIFLSLLVRFLDPDKPTWQRCLALEVLHKLITSPQHLSKFCRSYDLKPHATNICKDMVNALGAYVQSVFANPIGAMAVSLSTPTTGNAPNSNVTTNPANGPTSCANDASTIGFYFRGSLVPLVQVYQPSTPKPQLMELTDKQEPPNFATSESYGVAISFACLSDFVLSLVHIDKEIQDGQQEEAEVLKQLLSSSWPGLLAALNLLLEASIDDSITESICERLVDLATLSGKCSLQQCREATVLSLCVATLPPHYGYAVLKGTIGHGESPHPISYSEMDNGKQQVVHVGTSVVPSLALPPSLQSTPVMLTKKNLLVTHSVLRLCLESGAILLTSWLTVLTTLQHLCWVCACRAVATIVKLPVLNSTTSGFSTGVSELSVTSSSEKLASRKSFKSTNGAVGSSGGVMGVVVDFVSCLSQGVMRLIETSVALDDVSLHHVINALTNLSQEAMEIAYSNREPSLFAVAKLLEIGLVNLDRVEIYWRPLTNHLLEVCRHPHIRMREWGSEAITYLVRSALLHEDTEDEKVHQLLLSPLCELSSIPHNDVRNKQLMALSQILHCKGDKLKSSWPLAINILGDIYDNHSEGLVRTAFQCLQLVVTDYLPVLPCGCIPHAIDTVAKFARQKQELNVALSAIGLTWNIADFLYQNRARILENLTPDISVFPDFPGVSEIPQFDRLWLGIYQRLGELCIDERPAVRKSSGQTLFSTISAHSAILNRFSWDSVMWQVLFPLLEAVETSWKNASCLVLSGIAKIFSVKRQSLLEIKDFPKAWFFFLQFMQNGAMSNNEEVSLAALKSFQESLVAPQDFVGKEPEEMWTRSWLVYCDIGRKVICDHGAHQHFLTAYVTIFQYLFPALKLKLTLEDISAVNKVFSKSLLVPLTAEGASSIIFSSSENGITPLQDQIYNAYDILINETDGSPQLKVLLPPVIVQLIDFGAHAVRHSANVKVIPLEGVVPNCMEFGVKCLKRSLSVLERICTEKFILESDMFCHCLKSFRPILSSRFQNAEGSWRECASQFFLAVPLMVERKPKSPEFWDELAKCAQDFLFFTGNGEWMTKKAWKDEKMDVRMVTLLKELVFTNDGFLPAPFLIEVVKIFHRGSCINEYDGINVSEREEFVRFCFSSLLEFVLKGPSNVSEIVEMQSGDDGKKIAVLALLQRFQNILLNYKDYVNHNSHIPIQRHRLAEMNFVLRAIASLIENLKAADPTRVAGGTWEHIIGIYPDLVAIVGLPGVDTSISVALRDALMAYRDLLQRPPEAKFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N907</accession>
    <name>A0A1D2N907_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Organic cation transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04955</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000141">
        <property type="protein sequence ID" value="ODN01717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N907"/>
    <dbReference type="STRING" id="48709.A0A1D2N907"/>
    <dbReference type="OMA" id="WICNTIP"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="149"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="620" mass="69326" checksum="00FC2C7A9838C0A5" modified="2016-11-30" version="1">MDDSSGTNRKRTGDEDVYYGYLNSSNSKLDGNVKLEEMEPLNKEDHQNENGNNNFHSFTSISKAKDGQKKCGDFEEILEVVGSQGRFQKILLYAVLCPIVTVSPFLVLNTVFMWDIPNHFCHVPGKDPDMSIEEWKNLTLPFEKGPDQLLRHSQCKMFENGTSGKEIKCQFGWEYDKTDYESTIPSEFDWVCDRDHYATDCFTWGSVGSAVGTILFGIMADKYGRKPTFFLACFVNVLFKTVSLFVAHRYMVYKTLQFLGGFAFPALFSMPALISAEISGTTYRSWIYAVTWMIWVVGNSLIPFVAMICRGWFVFGCVAVVPGFFLFLYIWMVDESPRWLISVGKTERAIQIILKIARTNGIAVEPDVIDRMVQELAAKQKKEAEGQSLGVWTLFSRFQLAKNTVMLITAWTMNALLYYGVTLNATHMAGNTFLNYFLLSIIELPGGWLAGKLVETTGRRWTQSAFFLLCTLSCLLCAVAVAYPNSSLVVIIGALGIKFGVTIASLVVYLQGTEIFPTMLRSTGSGLASTVSSCVGIFGPYIVYSGTVHVSFPYAILCICSFIGLVSATCLPETFRQPLPESIQDANKFGKGQKFWSYLPQQQESGSDVKKRGSSMCEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAX1</accession>
    <name>A0A1D2NAX1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase dhs-27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000113">
        <property type="protein sequence ID" value="ODN02404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAX1"/>
    <dbReference type="STRING" id="48709.A0A1D2NAX1"/>
    <dbReference type="OMA" id="MNAWIAN"/>
    <dbReference type="OrthoDB" id="8250698at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="131"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="49107" checksum="D150E420ACC4BC1C" modified="2016-11-30" version="1">MSPIPKNEELESSNEVTQKYKDILKSNGVTDEVSEVIVKDSGLQGEGFASVSKYVTIKFQNPSVKPLNLFVKAHTASAAHREFLTEAKLFEKESTFFMEYVPAAEEFCKSKGCEGLVDMYPKCYFGDSNMIVLENLVVDKGYELLDKNEKQDLEAVRFAITTLAKHHAISYALIQEMGGPENFFKRFKNLNFEMYATSKARSIMEPMIENAINTNIKILQKNKYIPGADELIEFLNAHVGKAYDGMLDILNYNPKNEKLLVLGHGDYWTNNMMFLKNKDTNQIIGHLAIDLQVTRYNSPMVDLAYYFFTSVDSKVRREHLHEILGRYFDTLKSTALKLGHPIDLTYEELHKTYRRKIKLGFWFGICLATGAGFDSIKDVDVNTLGDLKNFSDEMDKAIQKWNDANPEKVVENIHNLRKLVNEYKMLSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB41</accession>
    <name>A0A1D2NB41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E3 ubiquitin-protein ligase MYCBP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000110">
        <property type="protein sequence ID" value="ODN02468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NB41"/>
    <dbReference type="OMA" id="QHVVMVM"/>
    <dbReference type="OrthoDB" id="6050183at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008582">
        <property type="term" value="P:regulation of synaptic assembly at neuromuscular junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.820">
        <property type="entry name" value="PHR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012983">
        <property type="entry name" value="PHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038648">
        <property type="entry name" value="PHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45943">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MYCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45943:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MYCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08005">
        <property type="entry name" value="PHR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="876"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="PHR" evidence="4">
        <location>
            <begin position="1154"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="domain" description="PHR" evidence="4">
        <location>
            <begin position="1618"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="686"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="806"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="686"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="806"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2223" mass="244362" checksum="308BBC29950D9386" modified="2016-11-30" version="1">MKTANPIENPKNAYWLKNRMLLQTFGKNAAGMPVEEVDVVELTRNFHSLYRVYHLKKNERKQNQKRDRSQRAKGKQKPKILVTSSVTTSLPLSTPIIEILGNSSIFAAYASVRQVVLEFNFADASRKWLIPLEDTDTENDNAGERLPSPVPVPKFLVYHPHCWARTGNCFSVNTRKSHGTHRTLCESLNGESLKKEPISVIDSMFSVLLILSKHEEDDTPSCSSSSNAFNSLTSVATACLISLAIARGETKSMFQAIASLFMCPRKLASQKLKNPNILKSVQRSAQAVLVGRPILPQWLNQGIPLNSCVDSFTLSFPSDPPGSVFSAKSLATDGRYLFLHCSRGLYKIGSGCFGTEKGKIYAYNNSFHTSEKVWIGWASGKLFCRLMNSANYMLLILDQVTFDVVGTVKVVEDVNCAMFSDGVSIGAIVPAREDGFMARTVWIDSSAASLESFFEINLRLVRKSVEIAGPCPWDNDTHLRPVSTGVDEDVVTITTGKDFALLRTQHGRIMYCGKGASLGQKSGLAKCSKWLELGLSKCPRFIQCAVGHEGIHSLLLTEDGTAYFVGTPKRGEDGDQAKIRRVAKASKPKKVIRMDGHDITFVACNNGTSAFVTRSGDVYMYGKDTAHCDSASGYLLGLRGVFVTQIAMGKAHSVILTGEGKVYTMGINNRGQCGRSYLQLKEDGTDVLEEDDGEWEDGAVPSSSTGGPPPEQEGMCPAGSHRWKHEQCMVCTVCRECTGYGSACISALRPDRNPGQECGCGVGDAGCAECGSCRTCAREGIEDQDYLVMDPQRVADPAVADLINLEEDRVLPHEESQERRSGGGKSGSSSSKSSKPKNKENSMTSFPPCRLSLPTSHTITQIACGLHHSVFMDAKGSVFVCGSNSFGQLGLGDLAPRHTPVKVRFPETSIKIIQIAAGSYHSVALDSNGVVYTCGAHAKGQLARTPEGSDVDPLWFSKMNAVQNVGAKYGRRVTWVGATGDSTFIRLEASLISQKILKKSTVTANSSSIMVIPPLSTGKTATVIMINRRDGSCSYFEGENNIQLPTSAATLDPTYDFLWAFEWRKHTMKCYNVIASAVRNPHVEANMCLMKPPYAIPIAPNSTLERWQAGASMLACMDTLIAAHIQGLSVHHEEQGAVPVLAKMYSRDDYSAVCRFESHGGGWGYSGHSIEAIRFSCDADILLGGFGLFGGRGEYCAKIKAFDIGPEGGEVEGDGELLAETEEIPYDCGPRQKFRMMFEDPVPLQAGRWYVAWAHISGPSSDCGSSGQSTVSTDDQVTFSFKSSKKSNNGTDVNAGQIPQILYRLMTSDSCSSGTKSKQSHEPAYLLTNDFVSNFTPGSVQVLMSLIRWCWDEIQSMSGEVRDSFTANLMKTVTCSCLRLIEFSINQIYPYKGCGRLGQMENLSMAEAIADVRVMLHNMISAQNDDSNIKSAKEEIVNQCCNTFEHCFQVFYPTSVLKWECLANFMYLYLEHGRKYARMLGSVVGALCRCRGQLLGIFPVLSSIVKQSPDDTCLTFVTNTEGGKLKQPANNRVLVGQMASRNDVEGFVKPSWSFWEVMQNLLTIINMDESAKYESIRVLIHNSSLLLAKLMEELVSHASGVYAELESVIGQIIVATPCRFTRTNQSRTWNTGNGSPDAVCFTVDQPGVSIFGCCIYSGTGTYEYEVELFQEVDELTIANCDQPNPKWTAIEIARGAFDSDECVGDISEIRFPKPIPIKPGIKYAIRLKNHGGRTCNGDGGVSVLRCPDGTTFTFSSCPLSFNGTNQIRGQIPHLLYFRNPDDSDARQKAKAVAEMQARKCALRACTAVFENAKRTMENTNTPEKISELSSSSLVTTLLPSLLAHLPHLAMSDPRVRNGRLKIILLVCICRICAVFVFFMLLKSSVEMLQLISLLLPPVTDLNNKMMSTKKDAIDDKETITRKCFVPELSNPGTYYSWVESEHPYKPAVIAHYKVKFPPSVQLMTVEFDPRCSTAQAEDSVRMYVPYGAIVSTSVNPLASSPPSQIPRPPQQPEIINNLVRPTLASPVDGPTSDDPHCLFSYIPIMERFTGAENWPKRAVILPGNEVLFSLETASDYARADKQHYFGFRCLITGFEWKECFGLARLEMELAYLGGFCAHELIKNDLVLPPVSDMSLIFVMTSLPFSVEEVETSLETSVCDEKMIDICLKHHALFAKGIGLEYFPGVQEALDGIVPLRISSDFILFMVSTSPITYLTKGMNPYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB69</accession>
    <name>A0A1D2NB69_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000108">
        <property type="protein sequence ID" value="ODN02500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB69"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="16842" checksum="3D8688EA8EAA39C2" modified="2016-11-30" version="1">MSSAGDFGSVTLSGNANLQTRGERNQGAITQTSNLNIFSINCVLNLYLISNGKMNTENSNIQVSLCPNLSVDGNGNTAVLSDNSNSKFNGDNNQWDAKDNSNLDVWGTGNILKINRNSNSKFGGDRCNVIAEDNSNLSVLGDDIKATIRGTSNHVVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBL1</accession>
    <name>A0A1D2NBL1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000102">
        <property type="protein sequence ID" value="ODN02639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBL1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905330" description="Transmembrane protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11320" checksum="DA836C2E034B624D" modified="2016-11-30" version="1">MASKIMKKLQTFLIAVLLGILFINSFASGDKDVDNKTETVVDGKQKEAEPGEVDWFGTDFKVCLTIAGIFTVVAIVACVYIAHKAKSRQDGVNLPKPLVDLGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBN6</accession>
    <name>A0A1D2NBN6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear receptor corepressor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N-CoR nuclear receptor corepressors family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBN6"/>
    <dbReference type="STRING" id="48709.A0A1D2NBN6"/>
    <dbReference type="OrthoDB" id="10258692at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051571">
        <property type="entry name" value="N-CoR_corepressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992">
        <property type="entry name" value="NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992:SF39">
        <property type="entry name" value="SMRTER, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="143"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="143"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="5">
        <location>
            <begin position="146"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="458"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="574" mass="63590" checksum="7BCE8549025B4366" modified="2016-11-30" version="1">MCYFCSGLGEKGVPHSCVVCKSSVESYMHSRPLMRTQVAQYGLSESDVQAGDRVCNTCRRCKSVRHRYKPSKQCPIPTCPAKKARVKRLRPFPAIWKDLSDEKRDAIMAKYQIPPTATKCCTACFNRINRRLSPNASLDTPDDPGSDTTRWTDDEIETMKKTLVEYGTDWRKLSEKINTKSDLQCRNFYFNFRKKYGLDALVQEYKKSKGGDGPPTLTDEEESGSTTSSCDETVAPSHDQSPRSSSNKNKDDYDSSATVSAEEGGAEAPEKPPNNPVTEMRSMPINPSSPLSLTVRHQQPAPERNQGPPPPSRIQSVAQQHQHNQENGQQQVTGAISLVSSHHSIIPPPQPPHSTMSSHHPQHPLHSPQITASLALQQRSSPNIQVHPSQQQQHPTYPTAVISHGSQINHHNQGQPQGIHHLNLHQARGVRYPSPEGPDGQEPPISVRVDDLMSATIERHLRRNPTASTSLNSGSLPPRDDCGTLDLSMKKRPASPNLPHQRPPSNGPPPAHQPLDYASRGPQGPPGDMYYAQKFQNAQRHPIQQQQPPQRQQAQLVPPPPKQAKVPPLPGTHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBW4</accession>
    <name>A0A1D2NBW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Endoplasmic reticulum-Golgi intermediate compartment protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_04109</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000105">
        <property type="protein sequence ID" value="ODN02575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBW4"/>
    <dbReference type="STRING" id="48709.A0A1D2NBW4"/>
    <dbReference type="OMA" id="FSHRIYK"/>
    <dbReference type="OrthoDB" id="5541786at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF30">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="8">
        <location>
            <begin position="171"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN02575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="50561" checksum="4343D39631711362" modified="2016-11-30" version="1">MSSQPQLRQRKPKVIKAVEELDAFPKVPETCIDKTSYGGTASITAVIIIVWLTVLEFSYYFDPGYKFHFSPDTDLDTKLTINVDITVAMPCAIIGADIVDSTNQNVLKFGELEEEFTYFELSESQRSYFNAKANLNSYLREQYHSLQQILWKHDFINLYSEMPKLSSKERFARGAATACRLHGSLELNKVAGNFHITAGKTLPLPRGHAHIAAFMSDRDYNFSHRIYKFSFGDNTPAVISPLEGDEKVANSNHMLYQYFIQVVPTLVKTKFRTYLTYQYSVRELGREINHDKGSHGISGIFFKYDMSGLKVEVEEEAYPIWMLLIRLCAVVGGVYATVGMVYNHLSLLGCSVRTFGRDRTKKDLYPPPTIQKSGHKKSGSISSNILTANSLVPPPNAVTPTLSFETPVVQLFGEPSETQPLCDLTKTDESSASNGLIDGHLPDLLASSRSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC66</accession>
    <name>A0A1D2NC66_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC66"/>
    <dbReference type="OMA" id="KYHCTRR"/>
    <dbReference type="OrthoDB" id="9970237at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029245">
        <property type="entry name" value="DUF4528"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34651">
        <property type="entry name" value="SIMILAR TO ENSANGP00000021391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34651:SF1">
        <property type="entry name" value="SIMILAR TO ENSANGP00000021391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15031">
        <property type="entry name" value="DUF4528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="167" mass="19057" checksum="ACB22FFAA9F45D84" modified="2016-11-30" version="1" fragment="single">CSILPRGTLRPTTAHRRNPVISILEACACKRTLFTKKPNASEVLTCHLESSGCPPWTSYFVKYESIANDQRGRSHFNWAVGGGKHNYHILRTGCYPYIKYHCSKRPYQDLRIEDTFFRVIKVMNLGIPCLAYGIAATYLIRHTEQVNTSKGPVTIYFLYAEDRGSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND14</accession>
    <name>A0A1D2ND14_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03549</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FKBP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND14"/>
    <dbReference type="STRING" id="48709.A0A1D2ND14"/>
    <dbReference type="OrthoDB" id="8116123at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034587">
        <property type="term" value="P:piRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042282">
        <property type="entry name" value="FKBP6/shu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46674:SF1">
        <property type="entry name" value="INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3 5" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="130"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="334"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN03142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="503" mass="56835" checksum="40A762282FA04BEB" modified="2016-11-30" version="1">MDLSFTDMHDYTEDFAHLVNPHSAHPRFQNPVQLMKMKMGEGTVFEVDELELDDGLEDDVEEVYDEDVLALFSFGGLDVGEKKKINTNADLVDVERHAHTDFPETEKLMKPLNQEGTVIHQGSELQVPERSKLYFHYAAICEGELEVFDTTMSRKYPAVMDLRKETTIPGLALALKSMCLSEVARFIIYPEMGFGKAGCPPRILPDVKIMYVIQVLQFIPEDKLNTLPYMTTDERNQLPFETIVKEAGRVRADGNRHYKDHSYGFAIKKWKRALSMLEDYPVTTEEDDKVRREYIWKLYSNLAQSYLKLKRPAQACSACKIGLKSVVENGLPKAKLLYRFAQAKLMLKDLDAALHLVSQALEIEPENAESLKLKAKIVADLEEGMKMFKNIFKSKGKTTGGNGKETEAQSAVKIQHIPDPEVKLPSDPLRSGFDMDDLVDDLAYCTPSQRELVEIDVQKAKTGSEKSPNRIRPVSLSNHLSNFFRGVAENGENINSADSGFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDB2</accession>
    <name>A0A1D2NDB2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000082">
        <property type="protein sequence ID" value="ODN03232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDB2"/>
    <dbReference type="STRING" id="48709.A0A1D2NDB2"/>
    <dbReference type="OrthoDB" id="10617911at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905394" evidence="1">
        <location>
            <begin position="21"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="609" mass="69744" checksum="1BB5BCA53CE8C503" modified="2016-11-30" version="1">MPSLVMYALQLGTLVSLSNSQLATWSQIYESPVIKDPKPGWARFCKGDEVYDTFANQCPVGIFWDEGNDNKWDCVCTRGPWRRSAGWCSDENTQRFTQGDITCFEPDGAESGGLQGLYYLGDRFSAWDSSLPILLSDYSSGIPIRKGDFSSEWEITSRSKMAPGVIIYRPRDDWSVENLMNSSLKLCLRAPSTFNEETEGLFIYNVSLFFDPSGGSQHLQLSFSRGCYSWNDQDTMTWYEITGESLEDKNMIVPKFNGRSAPEACSKCMSAQIPPAPDSDVDDGPLDEREEFTVYDLKNVAVLKTEIDLQTERLGQYWNYIMLKNANDSGTISSFQELEILTRAGIMAMSACDQSLIPPVFYQYFLILFRMLLGESFKKFAPKAPISDEYYERLGQLLEKCKERTKPIKFELSSTCPSLMEGYDGKQINMSASPDYTSDKGRHDFLLEFIWRLKSFLHYNCFEEFQMDSMLHDLVQAQLESLFTEDLILRWYNPGNSFNMYALMFDVHLDLDAAMKNFQRCVIVTKEISKYPVWLKRPIDRPEVIPREGSGGVEQRFKRDLKNEEEDEYADEDESKRVPNNLFGGKAACVKSIRTFMTESGKVADEKCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDF1</accession>
    <name>A0A1D2NDF1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03399</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDF1"/>
    <dbReference type="STRING" id="48709.A0A1D2NDF1"/>
    <dbReference type="OMA" id="HHAENVQ"/>
    <dbReference type="OrthoDB" id="421374at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00148">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000001">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005455">
        <property type="entry name" value="PFN_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027310">
        <property type="entry name" value="Profilin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604:SF0">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00392">
        <property type="entry name" value="PROFILIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01640">
        <property type="entry name" value="PROFILINPLNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00392">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00414">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="13566" checksum="4204B0EC5AEE38B6" modified="2016-11-30" version="1">MSWQDYVDKQLLGTKCVTKACIAGLDGAVWAKSDGFEVSKEEVAKLVAGFDNQDILTGSGVTLAGQRYIYLSGTDRVIRAKLGKVGVHCMKTTQAVVVSLYEDPIQPQQAASVVEKLGDYLVSCGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDY2</accession>
    <name>A0A1D2NDY2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000072">
        <property type="protein sequence ID" value="ODN03459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDY2"/>
    <dbReference type="STRING" id="48709.A0A1D2NDY2"/>
    <dbReference type="OMA" id="TDINQRC"/>
    <dbReference type="OrthoDB" id="46189at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="798" mass="90552" checksum="A8911D59F5A7F3D6" modified="2016-11-30" version="1">MAAPVAIQLAGAMALAGATPPPKSPTSPTVSSPGSQGFPAKTPSPFIDLNVRQVFETRGLDQTKEISKRVNSEIEKKREELRTLVGERYRDLIDAADTIASMNASSATIYGKLSTLRLRMGTLPNQLNSVPKTETVSSSTVFKSSVQLNKEELEIAFELKLSLEAPRVVQKFLDEQKVISATHLYLLFEQSLCQSDKPYRWEFLTNAAKKPLETGATIKNLILKACDEMMDDFSTVPQKLAECIVVKQVLMKSTCKDVLTAFLLQRIQMSEHCLKQTVNRDFVDNVAKTLNDIYIMFIDGQLYSSAVKEIRRPNISVTSFGLKYAPKIVDTFNQESIIIEDSPRASQLAQLLLTSYVHPLKELLNQCFHQNQYLVQQQSFEELNEYQKGTVDVLKHNTDDLMRIVLGTAKTLWSETFYPVFQLKCEQISRLKIEAIFKYLSEEAFPNYRKLDEDFNLMTYIWKASLPATSRASGSSSKDVDLKLKCISPQIAGICEEIEERFLLFLKDFKKLGDFSLKKFISQKILEEWQLFLNREVKNSSSSSLFLGRFVSSMGDLCSTIWKLMDVKDGNELRTNFSNVSEECWTQWANETSEKLLKHLQSKMDIDSKAVSAFMPVAEDFIPEGEEAVKPSIRVPLQISHILHSSLFILCNDLSHVGPQSIPKRVREVFRQSVGSKIIQFYQELIQKSAETPVSPQTAIQLIFDVKFCQWFHLQLKELTDPVIKTLQTSIDPFDMDIVSPKLKVNLKRFLFETHLTLGLLFSEESHSFIAQNFKTKMNMSFPTCNMSLNSPLPLLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEA5</accession>
    <name>A0A1D2NEA5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEA5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905433" evidence="1">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="89" mass="10294" checksum="FD69B74523AC081A" modified="2016-11-30" version="1">MQFLATSVYFMLLAFLLASLNGVHTFSRLNLQENSEHRFNTWRNERSAVEDASEISAFGPNEASWNLAQTSFKWEEMTREMMKNGNAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEB8</accession>
    <name>A0A1D2NEB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SWI/SNF complex subunit SMARCC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_03235</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SMARCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000073">
        <property type="protein sequence ID" value="ODN03445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEB8"/>
    <dbReference type="STRING" id="48709.A0A1D2NEB8"/>
    <dbReference type="OMA" id="KGGTIMD"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048858">
        <property type="term" value="P:cell projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049898">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032450">
        <property type="entry name" value="SMARCC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032448">
        <property type="entry name" value="SWIRM-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381:SF1">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16496">
        <property type="entry name" value="SWIRM-assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16498">
        <property type="entry name" value="SWIRM-assoc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52032">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="11">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="9">
        <location>
            <begin position="454"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="10">
        <location>
            <begin position="631"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="636"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="283"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="781"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="996"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="784"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1004"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1058" mass="117194" checksum="4DF5E3A516416532" modified="2016-11-30" version="1">MPLEARISGGCNTKFYDTAEVVTLFDSVKTWLMKNFKKYVQADPPNNKNLAVLATQLWQFQEDHFGKSEAKPLMTRIPTKFFYDFKPGGGLCQILGTAYKFKSDQSLRRFDFQAGGKSDKYIDMFLAIEAAIVQAKLWSQPQIYFTPLLLEREKGEIAKYKDIAKKHKATVVDDEESATHLIYPPLDPEEEYARAVFRKDKHVMIHFYYFPDNRDQWIKTDLPSDKAPGEQISICPPTHQWRVSANWLIDMKEFNEWMNEEDYEVDDSGDRKIHKLRMTYEEMEDLDSGEQSSSSGSGSQEKATPKAGVKKPERGKRKRTPSPPPKNSKRNKKGANAANNSGTPSKSSNSKNSSGSSTVPKIEDSEDYSRDFDDPPAETNLTEVQLPKAVPTKKLDTDFQPVKGGAVADLDEDANGAVDKNDDLSKMPDLTKSGREGQPDDAADDNVTEQTHHIVVPSYSSWFDYNSIHTVEKRALPEFFNGRNKSKTPEIYLAYRNFMIDTYRLNPNEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDADSRPTAMGPPPTSHFHVLADTPSGLQPINPPKTSQPSAAKALLDLDPDKKQEDGKKGIEIGTDFGLKLDQYSKKGAILKNKNVASMTRDWTEQETLLLLEALEMYKDDWNKVCEHVGTRTQEECILHFLRLPIEDPYLDDPAAGGGALGPLAFQPIPFSKAGNPIMSTVAFLASVVDPRIASAAAKAAMEEFAKIKDQVPATLLDSHLKNVTKHAAETGNLDPSAGLAQSGIAGTAPVEKEKDSDEKEGGSNAEEKDKDSKDSKESNDKLADKAVKKEDGQDGTTDDKAKTEGKKDESDKMEVDEAKPKDGDKQKTDSKDAKSADTDSKKTKADGESKETSDKSGEPDDETVSKDTNLQTAASAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLIAERQQFHLEQLRAAEIRARHHAHQKLISEQQQQQQQNQQQNPDSSAAVVAAAAIAAAQSAAATAPNPPNFGGPPAAQVTAAPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEE9</accession>
    <name>A0A1D2NEE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEE9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905442" evidence="1">
        <location>
            <begin position="19"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="69" mass="6838" checksum="3CDE02895BD6381E" modified="2016-11-30" version="1">MKAVVVLALFALFAAASAIGIGLGGLGYGIHYGGLGFRGIGGISHSQRSLQGGFPIGIGYYGLGHGFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFQ8</accession>
    <name>A0A1D2NFQ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Epididymal secretory protein E1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02574</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFQ8"/>
    <dbReference type="STRING" id="48709.A0A1D2NFQ8"/>
    <dbReference type="OrthoDB" id="6489092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.770:FF:000001">
        <property type="entry name" value="NPC intracellular cholesterol transporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905493" evidence="4">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="5">
        <location>
            <begin position="29"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="162" mass="17813" checksum="E3452F61A3E6EFA1" modified="2016-11-30" version="1">MKSLQIAVACCLLAILTVVAGQRNTPITVRNCRGETPKASLTSVFIENCTQEPCIFRKGQNYSIEMDLEILGPVESMEAHLYAKLAGISFNWGGNPEACNDIISAGPRCPLKTGDNITYGGHLYVSEHIATFTADFKYIVLDENRETLVCWLVKASVQEARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH98</accession>
    <name>A0A1D2NH98_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WD repeat-containing protein 44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02107</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000040">
        <property type="protein sequence ID" value="ODN04609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH98"/>
    <dbReference type="STRING" id="48709.A0A1D2NH98"/>
    <dbReference type="OMA" id="IAWSKSF"/>
    <dbReference type="OrthoDB" id="1932312at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000060">
        <property type="entry name" value="WD repeat-containing protein 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040324">
        <property type="entry name" value="WDR44/Dgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221">
        <property type="entry name" value="WD REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14221:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="687"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="781"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="821"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="296"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="394"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="579"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="733"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="579"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="737"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1110" mass="122371" checksum="3C634FA0FBD4E1E7" modified="2016-11-30" version="1">MSTTSSSDSSDERSEDSSDEFYDAEEPNTGTLLRFSRKVLEKQEDRPDLSKLTPAEVDSCLSDAYFSPGTSLSYIQHSSHDLSKASLNSLSKSQIEELEEDDRRRKRMEEMRRRLNTEEVEETPADENSQSDSQTSSVEGVYGAISGRTSHPFKVVDHDTVSLQSGVSIGRHGRVPGASSSNYSSSSASNNIGCSVQPQSAQDNANTTVNNNNQQQQSPQQVAQPSQRGIGGTMTDTVPSSSTPVISSSDNNSTNARVLVRSGSFVTEPDIVRSCKDKSGSLEIVDKAVMRAPIAPPRRKRKGMGFGASGSRLEELGGSTDDDARSKESTPEPFVMLSRQTSRIRDSEEGASGSKFSPQTPPSPTVSIRSMCKEMDKQLESPNQKFWIVKAQDEEKTRAKSAGPKVLRRTESLPKDVIAAFDPSGTGSGGQRESSSRSNSNSSTLNNSTTVLNVPDSNPAKVPSPVGTVAIAVSSVPVVNLNPSSIPKIPINHQLSSIISAIAALEESKDAECQLNMNLRTRTDSGKLLSDLEILEQVEVLNLDTGERIPLSSAEERIPKCINPLSLHIMRLTSEYISERDNKDRDSDEESLDSKKSSAASQEDGEQSNMKKKTAQVKRFLGSTVKKTVDKAKSLAHKRHRKEDVDISTNEGVVLGSGQEPLVKMKASHSHKGPYEFDQLQLVQDLSGDHSGPVWCMKFSNCGRLLATSGQDRAIRIWVLKDHLSYFQDMRSKNTSDKVSPTPSQESIVSQHSHHSVEEMMQASENSDPRAPFVPRPLCVYSGHTADLLDIAWSKSFFLLSSSMDRTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVTGQNKLITAANFCQNGKFAVVGTYDGRCMFYHTEQLKYHTQIIVHKGKKRLSGRKITGIEPMPGEDKILVTSNDSRIRLYDLRDLALTCKYKGYVNTSSQIKGTFSHDGKYVVSGSENQFVYIWKTYHDYSKFSSARRDRNGYWEGIKAHNVVVTCAVFAPDPDVIVRQIEAKEKEAEAEKQQRVGMVKSPSLTKPSSHGLKTQHASACPAGYVLVSADFAGNIKVFFTKVKPKHSSLPASALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHM8</accession>
    <name>A0A1D2NHM8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copine-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHM8"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="186" mass="21337" checksum="769B1C8BAA220000" modified="2016-11-30" version="1">MVKNLSCTIICATFQLITAFLVQSHVLKFKLSAINLPNADLDSPSDPYVQLFRTTWTREDFHLNWEKFGETAVKPNTLNPSWDEVFEYEYFNGTTQKWGFLVKDLDDSWLNPFDDPLGRVEINVDDYMFQLKHSNSNEKKPVNYIQLFLSQPIGGSLLVTPVVEQVETQPEQESAEETPAPETGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHS4</accession>
    <name>A0A1D2NHS4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000041">
        <property type="protein sequence ID" value="ODN04526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHS4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14703" checksum="5511DC415084ECA8" modified="2016-11-30" version="1">MEISITVSQPPLNQLLKLIFCVLTHQNPQTNIMHFATLALLVLAVVAAVSAGVYGPAVGLGYGAVVPGYELVLHSAVPSTDPHSSTVICRIWIWCWTRRLNNWTTSNFNLFVKIFFTFDTQAIIIMIKKLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NID5</accession>
    <name>A0A1D2NID5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thymidine kinase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NID5"/>
    <dbReference type="STRING" id="48709.A0A1D2NID5"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050566">
        <property type="entry name" value="Deoxyribonucleoside_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513">
        <property type="entry name" value="DEOXYNUCLEOSIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513:SF38">
        <property type="entry name" value="DEOXYNUCLEOSIDE KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deoxynucleoside kinase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="39032" checksum="6C69D1AF82754DCE" modified="2016-11-30" version="1">MLALKRFCCHSSSRAIFSDRSLVSVEGLSRSPWVVLKYSLSNINLSRRFVGTDRKMQQNQNSGKRVITVSVDGNISSGKSTLVSSLKELFPNDFRFEVDLVPEPLEKWTDLKGHNLLGMFYEDSVKNNFMFQHYVQLTRLIETIKRPSKVADLDGSHQGTVRIMERSLQNNRYCFTELARREGRLQPEEFAVLSEWHSWMEEHFNLNLDLLIYLRTSPETVFNRMNQRGREEESSVPFDYLKNLHETYEDWLVKGKVGNFGPALNCDGSDNNFRLDPNQKVIVIDANQGKAEVALQCKKYLIQFMSNNGYDYQNGTESNKPSSQKRKHSEIDNNVVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIG1</accession>
    <name>A0A1D2NIG1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01568</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIG1"/>
    <dbReference type="STRING" id="48709.A0A1D2NIG1"/>
    <dbReference type="OMA" id="CDWAVES"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811378" description="Carboxylic ester hydrolase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="595"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="7">
        <location>
            <begin position="28"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="623" mass="69644" checksum="95B120FC52B41837" modified="2016-11-30" version="1">MEIFQWFLTFILTFELSWAQLPSSSRITLQTTDGLFIGTKEPVDRDRSRREYYSFTGIPYAKPPILERRWQEPELLEIDGGTHHATSFGPKCPQYDSTTKSVTGSENCLFLNIYTPYIPGGGRGIQSARPLLPVVVFFHGGGFQKGSADTVGPKRFMRHDVILVTVNYRLGVLGYLSTGDDAIAGNFGGLDQIASLKWVQKYIRGFGGNPGRVTIAGHSAGGAAVHMLMLSPRALGLFHGAIIQSGSAFCDWAINEKPFNYAEKIGEIVGCFGGSFELASCLQEKSIEELIEAQQSLISFSSFPVLSSPVIDVDWRGEDAFLHGKPKELMDAGAFAQVPVIAGVTHDEGLSIYARLHLEVGAEQFKDQDYFENQLLPDLITNLLDNAEPLDVTVDAVKAQYFEEMDVENETKRVITELSEMIGDSMIYSCHWDMLERFAVDSRSPVYSYVFSHKTPASPSLSSSEIRRIRQMGIHHPLFNFGVSHGDDLFYLFEPIKGSNERMGQEDERVADIMTRAWVSFATTGSPASGLHLIPNSVPWRPIRPGNINYYNLTSMPSPMGEDFRKGEALFWLRTIPYIQQLGTTITDLQAYPTYFWIAFGVALFLLLVAIILLILLWRRRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NII9</accession>
    <name>A0A1D2NII9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NII9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="66" mass="6983" checksum="BB4EE8BB1E516E18" modified="2016-11-30" version="1">MDFGLSAAQLSTQHASVVKVDSTISSVPERVSSYPHVLKIGSIKKLIKEPPKNPELVPNLSTGTPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIK7</accession>
    <name>A0A1D2NIK7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 4E-binding protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF4E-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIK7"/>
    <dbReference type="STRING" id="48709.A0A1D2NIK7"/>
    <dbReference type="OMA" id="ININHES"/>
    <dbReference type="OrthoDB" id="19729at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008190">
        <property type="term" value="F:eukaryotic initiation factor 4E binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008606">
        <property type="entry name" value="EIF4EBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12669">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12669:SF12">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05456">
        <property type="entry name" value="eIF_4EBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="131" mass="13971" checksum="9628FD16C4523ABD" modified="2016-11-30" version="1">MSASPVARQVTQSQAIPRRVTITSTSQLPNDYSTTPGGTIYSTTPGGTRIVYERAFLMNLRNSPIARTPPKNLQMIPGLTTSPSISPSKLVLDSSNATPVIKQSEEVKVSVQAAQGGTPGVPVDEQFQMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJM5</accession>
    <name>A0A1D2NJM5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ubiquitin-conjugating enzyme E2 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJM5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="106" mass="11884" checksum="C8B65DD11B29184A" modified="2016-11-30" version="1">MMGTEEALEGQVIENGMAIEDAATPASRKKLLREYVRGEEESCDSMRGIPQQLEMKKQTTTIFGPDAVLWDMWILCLVLVNINLWIADAFGRDELVNQGFGYCQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK67</accession>
    <name>A0A1D2NK67_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enhancer of rudimentary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the E(R) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000019">
        <property type="protein sequence ID" value="ODN05641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK67"/>
    <dbReference type="STRING" id="48709.A0A1D2NK67"/>
    <dbReference type="OrthoDB" id="7887808at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2260.10">
        <property type="entry name" value="Enhancer of rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035912">
        <property type="entry name" value="EHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000781">
        <property type="entry name" value="ERH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY ERH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373:SF0">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01133">
        <property type="entry name" value="ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143875">
        <property type="entry name" value="ERH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="130" mass="15074" checksum="E62687866BB95EC8" modified="2016-11-30" version="1">MACQAVYHEVILLIQPLADPCSRRYWTYNSVNACMEGLCRIFEQYLKWRSGNDSNVVTVRYEIADILNFIDSLPDLACVVGNFCHSALENLNSFVTSRKRRSNGQFIPCAKAWIKEKVYLHLYEQAHRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKI9</accession>
    <name>A0A1D2NKI9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKI9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="183" mass="19598" checksum="2710F2F551E2B7ED" modified="2016-11-30" version="1" fragment="single">SVSSELSTREQYSGDTSTPPLLRIISISGVLLNLCLCVPTFPNIQQKSIGNFLVSWSCSYSLACFESETTGAATAKLIREALHIQLFPVLSSPIGIGNAVRFVSWNLEPGDGGGAPFLEFSVSNIKCVEEAGGDALNILLMCFEPCTYFYIGITTFWKGELRCIENGNMIGGNGESLTKIGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLD2</accession>
    <name>A0A1D2NLD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pancreatic triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLD2"/>
    <dbReference type="STRING" id="48709.A0A1D2NLD2"/>
    <dbReference type="OMA" id="EIGICTH"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00707">
        <property type="entry name" value="Pancreat_lipase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033906">
        <property type="entry name" value="Lipase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF173">
        <property type="entry name" value="LIPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00821">
        <property type="entry name" value="TAGLIPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="6">
        <location>
            <begin position="86"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="43469" checksum="3BC0FD61DF327850" modified="2016-11-30" version="1">MATTKGYTRCKPVTVIIVRAPGFLVVFLVLSLIFTYNFSCIHCQRFLPDIPNIFGLDFVSRVSPAIEELELDSMLPALPFYDKDVNNVGFYLYTADSDSSEGVFSEDYLVVNDPASVKRSSFNTKNQVKILIHGWSQKIKSRDFPGPVKHAYLEVASSGNNSVEHNVICVDWSSMSREFLYVNSVMYAEKVGRRVGEFIVFLKLGGFIQSYKQVHIIGFSLGAQVAGIAGNFVSQANEGKEKVGRITGLDPAGPMFSSESVPLNVRLDSSDASFVDVIHTNMGLFLRGEFGTPLPTGHADFYPNGGHRQPSCDLAIIRQYSLPRKSGCHHMKSIDYFTDSILGVHYYGCKCSEWNTFRSGLCDCQVDDNLVLMGENIDHESRGRFFLYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMI6</accession>
    <name>A0A1D2NMI6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMI6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN06447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="18182" checksum="B16D1FB27291B594" modified="2016-11-30" version="1">MEARKSGERTYDEAPIAVDLEESSNSFDAFTCYEPLSHLGLPNAALNDDDKKPIMKPLQLSNYDTPKIRKAQDFMHQPVRRRLIFSSQDEDDKENTPTKNYEDFTKYRTIADPVNKVEKQEISKNQLLQCHSDQNFDKSLQGVCNTIYGMNRIVHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0F5</accession>
    <name>A0A1D2M0F5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kynurenine formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01009189">
        <property type="protein sequence ID" value="ODM59394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0F5"/>
    <dbReference type="STRING" id="48709.A0A1D2M0F5"/>
    <dbReference type="OrthoDB" id="7108654at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43564:SF2">
        <property type="entry name" value="BLR6059 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43564">
        <property type="entry name" value="KYNURENINE FORMAMIDASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM59394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="22303" checksum="15FE74B569F88B33" modified="2016-11-30" version="1">MGLFPETTVHVQTAFSVNFLLLLQVFLGSFSSAYPIDRPEYIDLSYVNDDSTIFYPGQRFDYDLMQDVSGFNHTMQEFPYWFHSNYYYRLAMFSFCMGEHGGTHVDAPYHFNPLGWKLSEIPVERLTDVPAAVIDVERHVFALSRPDKYALEVSHILEHEAKHGPIPMGGIVLVRTGWSRFLARQAEIFRNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-03-27" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M125</accession>
    <name>A0A1D2M125_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007745">
        <property type="protein sequence ID" value="ODM86670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M125"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565674" description="Protein quiver" evidence="1">
        <location>
            <begin position="16"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="31713" checksum="3B507B1CF389E7AF" modified="2016-11-30" version="1" fragment="single">MKFLLLFLAFAGAHSAESVLKCWECQSEHGFHPFECDHINEGRSVDCTSPRAGLEPVCVAWIRTKDKGNGYSDVWLKKFCSWVEDSKIGDATENCGVHPGREEEKTVCWCKSKDNCNQEGILDQGKKGKLEDCGNLRTGAKSASTPPTLLALLTFGIIIIQLGKLRFNLLLLLIGLVTTSGFPAGSEALQCKNGYESDSHSIICNGTNPFCYIRMIDAYQPEEPQIYKGCLEEKEFTPELRHQGLNNHCIVDHTKSNIDVWCYCNDKDDCNKEAINEVGNRGPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M159</accession>
    <name>A0A1D2M159_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ERC protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_19988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Presynapse</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007625">
        <property type="protein sequence ID" value="ODM86693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M159"/>
    <dbReference type="STRING" id="48709.A0A1D2M159"/>
    <dbReference type="OMA" id="RTHFGLH"/>
    <dbReference type="OrthoDB" id="2019763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048788">
        <property type="term" value="C:cytoskeleton of presynaptic active zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098882">
        <property type="term" value="F:structural constituent of presynaptic active zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007274">
        <property type="term" value="P:neuromuscular synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048167">
        <property type="term" value="P:regulation of synaptic plasticity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019323">
        <property type="entry name" value="ELKS/CAST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18861:SF0">
        <property type="entry name" value="BRUCHPILOT, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18861">
        <property type="entry name" value="ELKS/RAB6-INTERACTING/CAST PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10174">
        <property type="entry name" value="Cast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0770">Synapse</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="33"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM86693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="19604" checksum="131CE35543C0C2B2" modified="2016-11-30" version="1">MHSIKTFWSPELKKERALRKEESARYSLLSDQLKLLNSENQKQALLVRQLEEELRLRTLRGGASLEMQRQMEALITENEHLVREIRILRETIKEFELRLETQKQTLQARDESIKKLLEMLQAKGLGKEEDRAMIQQLQIIAQKQIDDLRLEIQKRDQEILSCTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1N4</accession>
    <name>A0A1D2M1N4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_19815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006935">
        <property type="protein sequence ID" value="ODM86867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1N4"/>
    <dbReference type="STRING" id="48709.A0A1D2M1N4"/>
    <dbReference type="OMA" id="ITIFCEV"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF2">
        <property type="entry name" value="FMRFAMIDE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM86867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="24657" checksum="993AFFE79395473E" modified="2016-11-30" version="1">MRLNPDYILYYVQLSYLLVTFLIPFSILLFFNITIFCEVRKQRRYRNSLSFTSTNAASTNNSEDLALAGMLFGIVITFLSCNILLLVIRVMNIFKVKYYGSLTSISNFLVILGCSTNFVFYCLFGKKFRSQLARTLGMRKISRKGSKSSSNDSNFQMNSNDQTAVGRNSITSIISNESSSDGNQRNFRNKMSDTKPNAIENNVGEVSCSQVTVTSFLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2N9</accession>
    <name>A0A1D2M2N9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 4c3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19457</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005851">
        <property type="protein sequence ID" value="ODM87226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2N9"/>
    <dbReference type="STRING" id="48709.A0A1D2M2N9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="303" mass="34652" checksum="7EAD208644026069" modified="2016-11-30" version="1">MGIARIGASIIQIPMLWNLHPASRKYNKFVQNFNLAIQRVIARYEEVSGFEEKISKDNENDDSNDSMLALMSNAGFSREVIADEIKTMLGAGYETTSTTVELLLVMLALYPKYQNECRQEVDAIFNNDIKCPSGKLTLETLSEMKHLERCLFETMRMYPAGPIVGRKLETALKINNELEIPVGTTVGIPIVLLHRCPKNFPEPDQFQPDRFLAENCIKRHPIRTCRFQRVLGVALVPEIRFLFLAMKLAIMEAKTLVAYILREFEVETSDKIEDVTHIPSITVQLERGYYFRFKKRMDVPAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2Q3</accession>
    <name>A0A1D2M2Q3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005789">
        <property type="protein sequence ID" value="ODM87248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2Q3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="28" mass="3321" checksum="379958480F1C1563" modified="2016-11-30" version="1">MCVVSHAHETRSPEHLLWRDFLQGIRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3E5</accession>
    <name>A0A1D2M3E5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005345">
        <property type="protein sequence ID" value="ODM87431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3E5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903431" evidence="1">
        <location>
            <begin position="30"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="12290" checksum="5D3E9101226D55F6" modified="2016-11-30" version="1">MANSKIVFTFLAVLFAVAVISSEMESTNAETLQFNHVTITVPIIPFIVWNAARPMATRVEGEHAEKQLLLQDLNLIKTSWKLLSNYATRALIREFKKVEKIIGLISEIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3Q3</accession>
    <name>A0A1D2M3Q3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004975">
        <property type="protein sequence ID" value="ODM87605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3Q3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="167" mass="18922" checksum="14DD2B7BD19B9D0C" modified="2016-11-30" version="1">MRKSDREDVLAKGAYSLVQLISVAARLKTMDIFVDIVSSIRRSVNSEVVKNPGVTTIGYRGIVKSCPRDAIVQVVEIMTRVAVRELTDSNVPSDVKNEAEKLITVLRNTVGNSEFNIIHAQVNDFFHKKRNLNRAKKKETVMLHPGLVRKRPKNVKTPFPMKKRKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3V1</accession>
    <name>A0A1D2M3V1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rRNA-processing protein FYV7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004898">
        <property type="protein sequence ID" value="ODM87657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3V1"/>
    <dbReference type="OrthoDB" id="5377144at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013730">
        <property type="entry name" value="Fyv7/TAP26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08524">
        <property type="entry name" value="rRNA_processing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="20834" checksum="AE71296D0639EA20" modified="2016-11-30" version="1">MDEKMRSINKSSDEEDTPVRRKANNQTNSLKRFKKGKNSVAPAYLSMLNNTIGPGLKSKTGTKKATNDSSSAADRKSDGSATPKPSRIASNPKPSRNFSTPKTKNGDSRFTPKSRRPGRFSEEGVTNLSAKTPDYMKVKEEDSARQKKERRRYRNKIMNLKTAKGQPVMRGRINLMLEKIKADLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M531</accession>
    <name>A0A1D2M531_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">Ocin01_18596</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004131">
        <property type="protein sequence ID" value="ODM88086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M531"/>
    <dbReference type="STRING" id="48709.A0A1D2M531"/>
    <dbReference type="OMA" id="TIPNRLG"/>
    <dbReference type="OrthoDB" id="6232833at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF41">
        <property type="entry name" value="INNEXIN INX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="279"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="45043" checksum="63CA1914D12BA5E4" modified="2016-11-30" version="1">MDIWKNLKDVVQVDNRHVSITNFVFILHSKVSVFLLLCFSILVTSRQYLGDPIDCSSSADIKSIADKYCWIHSTFTRGALISDGKWGYEVVEQEESEIAPGIRPSVEQDSPRVYHTYYQWVWLVLFLQAALFYIPYWSWKMCDRGRIKMLVSDLNMEVIMAIDDDKLLRQKEVILAYLTPNIGSHTRYATHFIICEILNCANVIAQIFVTDAFLNHSFSSYGLELFSLSQKHPYQRSDDLARVFPTVTACRIATGGVAFGTMEYDLLCVLPINILNEKIYIFLWFWFLGLAALSILNLCYRLVVVLFPALRRVMLQRRTRKSYTINTDDKFYLSYPDWFLLTTLAENLNPVVFSEILNGIQNNVDDDYDDDDSPSTLTAINKNENNDLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M552</accession>
    <name>A0A1D2M552_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_18641</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01004197">
        <property type="protein sequence ID" value="ODM88042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M552"/>
    <dbReference type="STRING" id="48709.A0A1D2M552"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM88042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="19131" checksum="686B162F5C8F5AC1" modified="2016-11-30" version="1" fragment="single">LAGEELAFVKTLLENDVRNNSAWNQRYFVFLDLFGNFSEEALAKEVAETWEFVNAALRNESSWSYLRGIINLADPDFRMSLQKEVLSMCKPLLKIAESVPMTALYVDLIDELLSAGEDAYIKDYGEAISALDNLTSIDPIRALYWEFVKRKFMAAHAEIAEQKGCCLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6F6</accession>
    <name>A0A1D2M6F6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003426">
        <property type="protein sequence ID" value="ODM88558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6F6"/>
    <dbReference type="STRING" id="48709.A0A1D2M6F6"/>
    <dbReference type="OrthoDB" id="9831996at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="188" mass="20664" checksum="7F431C667AF4A594" modified="2016-11-30" version="1">MLKMQKPQIISFSHNDDDHYAFRVQYNFCNTSYVNIDGVFGQLSGKKETHCSLDFPRGDGGPLVVVGKTGSLSSNTLENVVDKGVHDGHGFGGDSSVGVNLLQHLVDVDSVGFLPLVLALLSISFGNVLLGFSCLLGSLSTGLWWHVERVVGLLGERVISNFQVESERVNDAVQSERLLFIWRERVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6V2</accession>
    <name>A0A1D2M6V2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003285">
        <property type="protein sequence ID" value="ODM88710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6V2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="15525" checksum="2FC31BA9E03C2F62" modified="2016-11-30" version="1">MSAGQLVMEAESVQIIQQYQEFSTLSILVPVTQQVLSIAKWRNDTGNNRNRITAAFLKSKYNSMTFADCKFLDRSKGCSTPTTVYRSTGTVPNESIGLPWVIYHGTLESQTCVLYLSSPSPELVIFKCIDATNTSVLCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7P3</accession>
    <name>A0A1D2M7P3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003047">
        <property type="protein sequence ID" value="ODM88942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7P3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="105" mass="11919" checksum="489DE689DB476108" modified="2016-11-30" version="1">MLRLFESGENPLEGLEWKWITEGCKIEVSGFDLIAYIGMGNQKTCMDSIRQNPNASIISEIPHCENQESYKGCWSTVMDALNTCVQTVKDVAVLFISDWTTRYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8Z2</accession>
    <name>A0A1D2M8Z2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17239</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01002636">
        <property type="protein sequence ID" value="ODM89445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8Z2"/>
    <dbReference type="STRING" id="48709.A0A1D2M8Z2"/>
    <dbReference type="OrthoDB" id="1925699at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="4">
        <location>
            <begin position="44"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM89445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="403" mass="45806" checksum="944D82BBE3750209" modified="2016-11-30" version="1">MAFQKVSWVYWISFLVVFTNSFLSSFGYICDVPQEWFQDINGTKAHNSNNSLWINGIVKYRFHPSLSKEDRVEVWKAFEEYHSKTCIRFQPWRKGDPDYTEIMVDSEVCGRAEICRKGGYQFTKFGNDCRSMAVMIHELGHTLCLYHEQQRPDRDDFLDFGNCDEDEIFPIAQFSDELSSAIYDYGSQMHYQCKTCLGGWPSTSGVTKCGIDITPGLSVIDADNINRLYNCQGCYRHRWRPIENLTPDDVNNMYNFGYKSSYGYIYPCRGLVNGEISVGKYSVRSKVCTVSHQGLEYELERGAEVLTIPGGRNQHGATYRLINQRHVKFPENVIEAAVFAGRKSEDEGAGPTFIAFATLKTGLLGTEDSIGMVGLQKGQFQNAIVTINKKVVTVENYLILVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAP7</accession>
    <name>A0A1D2MAP7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CD63 antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002281">
        <property type="protein sequence ID" value="ODM89944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAP7"/>
    <dbReference type="STRING" id="48709.A0A1D2MAP7"/>
    <dbReference type="OrthoDB" id="10033535at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03127">
        <property type="entry name" value="tetraspanin_LEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF562">
        <property type="entry name" value="AT12771P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM89944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="28586" checksum="521E0AD0C71C5811" modified="2016-11-30" version="1">MMQNCLVFTAFIAPLFLGILLVWGAFAAKNGIVWYFSRILDNERIELTNFTIPLILLIVAGVFTFLLVFFLVVAINEKKTIFSNLYVIMIDCTMVLELSALYMLFITDADGMAKNTMYNSMGNYYNEGSSSQNVSVQFWDYMQENLKCCGIYGYTDWVAAEQAPEVGFIPKSCCIEDIQTSESCTEVITKDKINSVAFIKNTIYMDGCLSQYNSFYGIGLLEVIAIFSIFCQVCGIVTVCSVVNNRRSGYINMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB96</accession>
    <name>A0A1D2MB96_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SprT-like domain-containing protein Spartan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002075">
        <property type="protein sequence ID" value="ODM90267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB96"/>
    <dbReference type="STRING" id="48709.A0A1D2MB96"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044245">
        <property type="entry name" value="Spartan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055220">
        <property type="entry name" value="SPRTN_ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220:SF0">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22934">
        <property type="entry name" value="SPRTN_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="4">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="322" mass="35325" checksum="4B95BA9D5D6FB168" modified="2016-11-30" version="1" fragment="single">MAAGKYYSLVDASWELIDPCPDVHELFCEFNKEFFQGKLTSVYVDWSSEMKTSAGLTKCAYLGELRDCSISLSEPLLSLRPRRDLVETLLHEMIHAYLFVVEGSRDREGHGPDFLYHMNRINRLTGAKISVYHSFHDEVDYLKPHWWKCGGRCQHRPPYFGVVKRSTNRPPGINDLWYNDHQRTCGGTFVKVKEPKPYPTKTVKRPKSPPRASSSTAMKTSKMVPPPKAPNAQKPTTATSAAPSSSSATSSKSLRKPSSSPGIFSSLLGSHSTAIGVGNFIAAAFPGKGHTLGSSSNGTKKTTSASASSTKPKPRNGRGGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBB7</accession>
    <name>A0A1D2MBB7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_16386</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002050">
        <property type="protein sequence ID" value="ODM90296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBB7"/>
    <dbReference type="STRING" id="48709.A0A1D2MBB7"/>
    <dbReference type="OMA" id="CSYPLID"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="9">
        <location>
            <begin position="49"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="10">
        <location>
            <begin position="117"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM90296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="425" mass="48714" checksum="7E69D4514EA6B36B" modified="2016-11-30" version="1">MNMTLIQNDVEATLFPQVSTRLFEWSRRISDFFTTRSSRFFGLKEPLNTTQLIEAQGYPSETHQVTTEDGYILELHRIPHGLNSQRNVSRPPMIVFHGHWRTSADWVINQPKEDALGFVLSDRGYDVWLANERGNGYSMRHISLTPSDPKFWDFSIDEIGLYDVPAIIDYVLKQTGYKKLHYTAYSLGGAELLVALSKRPEYNEKVQNAVLLAPAVYLQNFVYGILKFLSPVAPLLHQIFNVQLDGFSFYPPLFTNLYHRILPVICHPRVDIFGVCMLGFRTFYGNDMGLIPRTKLPLITMVAPSSSSVKKGIWAIQQMGWGEFSQYDYGISRNREVYGCDKPPRYNLTNVHVPILIIIGLNDIISSPRDCRTLAKRLPNYVDVHYVNNLFFTHSSFTYAKGVGELVYSRIVKAHDAFRLTREPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC80</accession>
    <name>A0A1D2MC80_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription cofactor vestigial-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001883">
        <property type="protein sequence ID" value="ODM90607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC80"/>
    <dbReference type="OrthoDB" id="10040691at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001223">
        <property type="term" value="F:transcription coactivator binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006627">
        <property type="entry name" value="TDU_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028184">
        <property type="entry name" value="VGLL4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17604:SF7">
        <property type="entry name" value="TONDU-DOMAIN-CONTAINING GROWTH INHIBITOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17604">
        <property type="entry name" value="TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00711">
        <property type="entry name" value="TDU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="296" mass="32822" checksum="BAC198B39E9AFF50" modified="2016-11-30" version="1">MLKNGGVSKSPEYESHSVHSCDADDEETHERVAVYDDQPLDMTCKKDARKRALESDDQGSAEGNGLQDPKKLKCSGAKRKLLRKKRYHKRVSDVQVSRPSVISFAGSSGNYTSSSSNEEPEEDDSRARRRKKMNDRKKLFVHADVEEHFRRSLGGVLYDLVNKQEKNEESRNSIHSSAGDPQDNFVAEVIRPSDVDDHFAKALGTETWSKIVKNSRGVNSSSSTPPLQEHRTTPPAAATLNPTPPPTIVSKTSNSYKIESILGTSVSASERPTIKQPPVYDNTRRSPPPPYTTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCP5</accession>
    <name>A0A1D2MCP5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16002</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001851">
        <property type="protein sequence ID" value="ODM90681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCP5"/>
    <dbReference type="STRING" id="48709.A0A1D2MCP5"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="299" mass="33256" checksum="6571579CC568570C" modified="2016-11-30" version="1">MEGTGQDGNTSGFHLNFSLSDIKPDLDPKPITSGCKDVGSITFLGRSFRMRDAEELLQLRRDLASIKMEKTETASDMDTDTGMSTYAVLNDKVNKLAEMVEEIREQLLPSSGSINANGDHTQSSMESSNSTRCEENIVSMDMKETSNHSPLGSGPPSPFTGNSIINSAASADSQNGTGEDNGEEQSPINSNPGSTPLNNKAFPMIPNYIDITVLPGKPVLYRCNICQKRFNLKVLIMNHDNCQKEESIFKCQECGRGFINKSHYEYHIRMHERQLKGHERTERVGGYKGPRFFLPQIFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDC6</accession>
    <name>A0A1D2MDC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Acetyl-CoA carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_15664</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001701">
        <property type="protein sequence ID" value="ODM91016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDC6"/>
    <dbReference type="STRING" id="48709.A0A1D2MDC6"/>
    <dbReference type="OMA" id="HASENYK"/>
    <dbReference type="OrthoDB" id="14612at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000005">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000005">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="17">
        <location>
            <begin position="39"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="187"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="15">
        <location>
            <begin position="628"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM91016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="712" mass="79087" checksum="3DCE017CFDE58B19" modified="2016-11-30" version="1">MAPSMSYGTMLRDSRFVDSRDLIFATTEELMKKLGGTRNINKVLIANNGIAAVKCMRSIRRWAYELLRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGANNNNYANVELILDIAKRMQVQAVWAGWGHASENPKLPELLHKNNIAKSNVGSRRQDASSIVAQTAGVPTLPWSGSGLIASYGKDKRIKIASDLYKKGCVETAEEGLVAAQKIGFPVMIKASEGGGKGIRKAETMDDFNLFRQVQSGAGSPIFIMKRRHLEVQLLGDQYGNAISLFGRDCSIQRRHQKIIEEAPCVIAKKDIFEEMEKAAVRLAKMVGYVSAGTVEYLYDTDGNYFFLELNPRLQVEHPCTEMVADVNLPASQLQIAMGIPLNRIKCIRTLYGEAPWGDSLIDFDTPRYKPQPWGHSKNLISVFQNVWGYFSVAASGGLHEFADSQFGHCFSWGEDREQARENLVIALKELSIRGDFRTTVEYLITLLETPAFQDNTIDTSWLDALIAERVQADKPDIMIGVMCGALHVADQTIVNAFQNFQTSLEKGQILPANTLRNTVSVELINEGTKYKVEAVKSGPNQYFLVMNDSIKEVEVHRMSDGGLLVSTDMQSFNTYMKEEVDRYRVVIGNQTCVFEKENDPTLLRSPSAGKLLGYLVEDGGHVYAGQAYAEIEVMKMVMTLTCSESGCLQYCKRAGAVLDAGALIARLSLMTHPKSPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEY5</accession>
    <name>A0A1D2MEY5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001502">
        <property type="protein sequence ID" value="ODM91559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEY5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="85" mass="9157" checksum="F36AB593B72E1D26" modified="2016-11-30" version="1" fragment="single">RNYFLPVKTVQLFTKRRLSTPLPKALLILLVIIGVIYCAHSGSGFETDGGCETFCASCDQGGVVNSEVENLMSECDCCVPPITGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF14</accession>
    <name>A0A1D2MF14_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aryl hydrocarbon receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_15150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001519">
        <property type="protein sequence ID" value="ODM91533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF14"/>
    <dbReference type="STRING" id="48709.A0A1D2MF14"/>
    <dbReference type="OMA" id="TVLMWAH"/>
    <dbReference type="OrthoDB" id="6099906at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034751">
        <property type="term" value="C:aryl hydrocarbon receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004879">
        <property type="term" value="F:nuclear receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19730">
        <property type="entry name" value="bHLH-PAS_spineless_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000069">
        <property type="entry name" value="Aryl hydrocarbon receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000074">
        <property type="entry name" value="Aryl hydrocarbon receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000041">
        <property type="entry name" value="aryl hydrocarbon receptor repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039091">
        <property type="entry name" value="AHR/AHRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10649">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10649:SF12">
        <property type="entry name" value="SPINELESS, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14598">
        <property type="entry name" value="PAS_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="9">
        <location>
            <begin position="43"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="133"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="414"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="492"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="520"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="745" mass="83870" checksum="EBED66117A84A3C7" modified="2016-11-30" version="1">MHLRRKRVWLVHHNARDSEHSPMISVHFLNPFGRNDDIKPPPKDGVQKSNPSKRHRERLNAELDHLASLLPFEQNILSKLDRLSILRLAVAYLRTKSYFQGDYNGNQARRAILTSSSEMTALDHTPLDGELFLQALNGFLLILTCDGEVFFATHSIESYLGFHQSDIVHQSVYELVHSEDREELQRQLIWNAFCPSELSGISLTETIHTPDHYSFLERSFTVRFRCLLDNTSGFLRLDIRGRIKILHGQNRKTEDPPLALFALCTPFGPPSLLEVPQKEVMFKSKHKLDLSLVSMDQRGKMLFNYPDSELTTMGGYDLVHFDDLAYVASAHQELLKTGASGLIAYRLQTKDGTWQWLQTSSRLVYKNSKPDFIISTHRPLMEEEGRDLLGKRTMDFKVSYLDAGLTNSYFSDQDGSTINSSTPPNHTHNSTSNGSSGGTPTPSTKTRKYKTQLRDFLASCSIQGLESLSKLHINPITLTHYIQVTPIYNRSKRKVAAQQPPAQPPSQQQQASIPPILHHAPPPEYYGSLPPPTPQLEQQSSTLLHPPPHHHHAAAAAAAAAAAAAVSYSAAVAGSTQPYNSMLYNNYATEYPSNNYYYENRYLQDSLFNYRYYPEYTNWGTTYENQNGIEYKPYAPTTTSKDKPIEIKSEYIYTNGSDSSLPSSQIPRQTVLMWAHHNNNNRGSSSSSEKKYSILDPLKSLTGVVGAVETSYSEPPEVWNPAATHSNSISTTNTLLQQPTPSHCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF20</accession>
    <name>A0A1D2MF20_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sequestosome-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_15241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001544">
        <property type="protein sequence ID" value="ODM91451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF20"/>
    <dbReference type="STRING" id="48709.A0A1D2MF20"/>
    <dbReference type="OrthoDB" id="441278at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02340">
        <property type="entry name" value="ZZ_NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052260">
        <property type="entry name" value="Autophagy_Rcpt_SigReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15090">
        <property type="entry name" value="SEQUESTOSOME 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="5">
        <location>
            <begin position="310"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM91451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="389" mass="44374" checksum="CFD4DE67755EFAEA" modified="2016-11-30" version="1">MKKHTHTICTFCKTNLPVCSKCGKGGNVPTLPEDNTLFDCVYKEKGCLERLKREEVFQHVKTCRYKSDSIQLCKLLGFAHCKYVHKLDAERSQIIRHFVEEHGSEVGRGKNGLRISLMGITKLSDSSENSIWRPVLYSFDNEEGENNAGPLFLITGKVDADTDCATWTCIKLWGKQVKANEEEENYDAEFVLENECKGCYKASWEFGGPSDQLPSVKWTIPVADAREEKCHLEASPILIPLRFVRKLFVINRTHVNMVVTIRNKKQAGKKTIKSRKEEFNQVLTVGVPLETGDKEKVEIKMKEKEKVVLANHIICDGCEQYPIIGTQYKCLQCPDFDLCEECMEKGVHSFHVFVVLANKTQNQIIRQRRSRSGLRQLKTAVNEGNLRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF35</accession>
    <name>A0A1D2MF35_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001482">
        <property type="protein sequence ID" value="ODM91606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF35"/>
    <dbReference type="STRING" id="48709.A0A1D2MF35"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF176">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="295"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="445" mass="48538" checksum="5E7D40E21B7A0D8C" modified="2016-11-30" version="1">MVESSQQFTGEDENWRGELVIPQEGGVYPSKLGGGCHIIDVDYFVKVVAQVQSCCKADLEVFSSIIIGTCRTAAGIRKVPFSPITSLEFARAKIIMSVEAFEVIPDKLEYWPGETVRGKVVLKVKSGFQTQGIFLNLKGGATANIVEQIVRRSTRKSIGGRSHSTSRVYTNRFDNSESFLSMNSFVAGDGRTLLNLRDGETSYPFSFQLPSRLVSSYYRCNGEIPLGWNFIQGTGQVSYYLELGMIVAGKAEHVSQKVIGVHTNLDLNIVPDATQPGEAEVTKIFCNSCACCCCQSGPLVLKVRTDKRGYLPGESIAFDFEANNKSNKTIKQVSAQLVEAVTLNGQGRTERVSIPVGGLLVSDHQFVGEVDNWRGELIVPKEGEVYPTKLGGGCSIIEVDYFLEIKVQVQGCCNGDSEVLSSIIIGTCRGAARVPSTKSKSLFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFR9</accession>
    <name>A0A1D2MFR9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001406">
        <property type="protein sequence ID" value="ODM91830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFR9"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903958" evidence="1">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="168" mass="19292" checksum="29E9AF4EC0A8E408" modified="2016-11-30" version="1">MTFIFAYNSLLLFLLTFLFIRIDSFSFNGSGEQGDCPRNGRFFCRRRAVAHPRESDSMLPRWHSRSLSFHEVLLPRAVNSTRGKCKLPTANPLKLNNTTSGSGAFDFQQTNCSSDSEVYSERLQRCVSTMGGGGFAEIWKWFFSGSITRRCSNQYYRSYARRCQNGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFU0</accession>
    <name>A0A1D2MFU0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001430">
        <property type="protein sequence ID" value="ODM91752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFU0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="653" mass="74864" checksum="0A3BFE302DAB0B88" modified="2016-11-30" version="1">MTSPNHHGPQIAVQSASQENLAQDGPRLERGRNNSAILMKTQGSHHSQRQFKTSPSTHSRNREGSFQNTIFGISPTPVHHQRLSVQSRDESLPQQWPTKELENAPELAILNKKPTHYTSGRSQNSYCAKLLRCFGTVCKNKVADSCGLDNFNPVIARTDNNVEFVNMLLRAYVVNMRYGKGTASRTSLQSGSTSTNKHSELSKDEHREVGSKNAAMKELYEHAHKTLLILQQCIGHFKQMIFTLTFTKYGDEPLTEPEIKMTRGKSIIGSCIWIVVYALQQLQDDPDIEPAESQPKPHQGVHDLANEMQHLINQSFYTWHEMVIAVGALERMHKKTEELFHRQTTHFHTTSAPDSEAANVAGLHLKKYRRGDADIEELKNLRNFDPYATLLVWNNRIGLSRILYKTEYTRPDTLWWGFDTLSVDKKVAYLKDVLNFLKRIFDSVKEVAQKISNELQGRFISRRGSYMPSASARHSGGYDPLSGVANYEEGIDMMDKVLTRKLLHYDWTPEEVHEFFEVDKIFLDEMDVLTLGAGVTRAILHEARHMMHICYETSRLLDFKEFAMLPSYERVYNRLKDEFMEKTQQKKIRRMSTGTTSYDIEEGHLELRNVTGLFRTSIYNEILKNLPLYCSRVALTLQDSELVFTPSSEKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH55</accession>
    <name>A0A1D2MH55_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001262">
        <property type="protein sequence ID" value="ODM92338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH55"/>
    <dbReference type="STRING" id="48709.A0A1D2MH55"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="17611" checksum="A3D31AB035F1BDEE" modified="2016-11-30" version="1">MNRKLNNFFLVSVGIVDGERLDESSVKLTGGAVKGQHLTFQTMLIRIARDWKSQGSEHRLDSKGGQMELQMIFTIAGSADPIKYWHVLARVQNRLFQFREKLVIILSVLVDALETEEDVIRKIEEEGTLQDPYLFEPFTQAVYHFRKEREDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIC6</accession>
    <name>A0A1D2MIC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Collagen type IV alpha-3-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13931</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001156">
        <property type="protein sequence ID" value="ODM92757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIC6"/>
    <dbReference type="STRING" id="48709.A0A1D2MIC6"/>
    <dbReference type="OMA" id="LETCHRI"/>
    <dbReference type="OrthoDB" id="2344588at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001881">
        <property type="term" value="P:receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13283">
        <property type="entry name" value="PH_GPBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000104">
        <property type="entry name" value="collagen type IV alpha-3-binding protein-like isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045188">
        <property type="entry name" value="Boi1/Boi2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902:SF27">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902">
        <property type="entry name" value="SESQUIPEDALIAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0176">Collagen</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="24"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="294"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="462" mass="52341" checksum="D2505D74744BABDD" modified="2016-11-30" version="1">MSQDPSPSLTDEEDDIIFDNSSPRGVTNGVLSKWTNYIHGWQDRYIVLREGTLSYYKSEFDLSFGCRGSISILKANIKPHEFDECRFDVSLNDCVWYLRAANAEEKSKWVEVLEVSKRESGYGSQNSLKRHGSAVSISSTTQSTASTSSFHRGRSLNAKLSELENYRGILVQQIDTLQKYFDLLATATNGRICDFELPNNTCNSDSSLVNSSVEDLDTPTPTACEGTTESPFFRPPEKFDTTSLNHALTQSGLKIVDFRGEALTFKATTAAIINSVSSCTEFMTQREDLWKKKHEREVQKRKKLEENFNQALKEAQEKKAAMGGPDCEEGPHSTLNEDEFYDAVELGLDRLEEEAAFKERLKTIKLNTSLSKSQNHPLWAEIDRVTLEQLHYAKLGVGEGGWDIFAEEGEMRMYKREQEIDGRVVDPLKAVHTVKGVTGHEMCHYFFSPDVRMEWESKLIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIL6</accession>
    <name>A0A1D2MIL6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clavesin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001154">
        <property type="protein sequence ID" value="ODM92771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIL6"/>
    <dbReference type="STRING" id="48709.A0A1D2MIL6"/>
    <dbReference type="OMA" id="RIVIHRT"/>
    <dbReference type="OrthoDB" id="6682367at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="121"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="31237" checksum="B9C0967C38F08F2D" modified="2016-11-30" version="1">MGLKKKPTVPIEQLLTSLRVLVEDNEDIVKSGIDINDAFLLGFLIGRKYNLTTAYETIQKYVDVRKRKYVHIFSTFLPESFLYLYDQPKFMAVLKHREKNTGCIVGLLRPSRDQRAIRRPFEDVLGVCALASDQLLYMEDAIENGGIMVISGEGCEFSHIKEITPTRLKMALDIFYQAYPISVKQIHIVQCSLIFNTVVTLLKTLLPRKLRKRIVIHRTLETFHEIFDPSVLPSWLGGNRLEEQDWEVLDNYFERVFLDKADYYDKLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIW6</accession>
    <name>A0A1D2MIW6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock 70 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13737</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001114">
        <property type="protein sequence ID" value="ODM92946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIW6"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10790" checksum="F5979810FC491F1B" modified="2016-11-30" version="1">MQKQVNQSAITRSTARIPLKESKISLLKQALERSFRKYEDENTMKLNWELGAEPAIGIDLGTTYCCVAVFYEGRTIVIRNAEGRNQHQATWLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK92</accession>
    <name>A0A1D2MK92_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphodiesterase</fullName>
            <ecNumber evidence="8">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13243</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000987">
        <property type="protein sequence ID" value="ODM93439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK92"/>
    <dbReference type="STRING" id="48709.A0A1D2MK92"/>
    <dbReference type="OMA" id="FHIPYEV"/>
    <dbReference type="OrthoDB" id="74705at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1300.10:FF:000003">
        <property type="entry name" value="Phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0140">cGMP</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="10">
        <location>
            <begin position="577"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="53"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="958"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="962"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="990"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1009"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="653"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="653"/>
            <end position="657"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="657"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="694"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="694"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="694"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="804"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="804"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="850"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1035" mass="116838" checksum="95DCC17633E01472" modified="2016-11-30" version="1">MESTPPVKSELEAYLESHPEFIQTWLKERASPETKRKVLGCCSTPVISTTLTEQSSNNDTINTSSIVNNNNNSSAVNNNTVRAGSPPGAEQAGESSTRVKTSSSPIPERSPVNDSCKPSAAGENDEITTIQRPRSHSKRNSITSDRFQSWISSPKHKSDRTVPPGLVASQLEHLDENELFIELVKDISNELDIDILCHKILVNVGYLTQADRCSLFLARGPSEQRHLVAKLWDVTVDSDVEESLRRAKLEEIRIPFGVGIAGHVAQTKEIVNIKNAYEDARFNVQIDSKTGYKTHSILALPICNNEGDVIGVAQVINKKTGDFQFTEEDIELLLNLAKSIFEEQTNLERLVSKIMKEAQELLKCERCLVYLRDVPLYEASQIEKIFLMPSLPASSGDRKPLSRRESKTASSPEVVTEESINFQMVFELKNDDLEREVRRPSTNEIQNSPLTQIAKYVAANSEILNIGDAITWYGESMDVSTSNEVVRAQPPNVYNALPKSILCMPIYNGQRQVIGVAQLINKSNNQHFTHTDVNTFEAFAIFCGLGIHNTQLYEGACKLMAKQSVALDCLSYHATATPDDTERLRRDEIPSSIHYNLYSYEFNDFPMTDSETCKATIRMFLELDLVRKFHIPYAVLCRWVLSVKKNYRHVKYHNWRHAFNVAQTMFTVLKTGKMEQFLDDHDILGLLVACLCHDLDHRGTNNAFQRLTASPLAVLYSTSTMEHHHFDQCVMILSSEGNNIFQDLSAEDYRKVMKIVEKSILSTDLAMYFRKRARFIELVENGEISWQGDDKKELLCGMMMTGCDVAAISKPWEIQHKIAKLVADEFFDQGDLEKEQLNQKPQKDELPKMQLSFIDEICLPLYKVLSETFPWLQPLYDGASRNRQNWQDLAEKVDMGLTWIDYDVIEKPVEEFTKDAEPEDIDFVVQNLNCPHADAEHESGKRSKSKWKLRKLFRETSQLRKSTSSQSKASSDVNTFHSKKDDLPADVPNAFNSVSNSQGTEHISDETSRPTSKPSSPATNGAPHSSGRKGNCQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLY9</accession>
    <name>A0A1D2MLY9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000887">
        <property type="protein sequence ID" value="ODM93932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLY9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="235" mass="26559" checksum="EF9A5D868874B8FE" modified="2016-11-30" version="1">MYTKPRLKCADLGKAARDVQHVSEQGPHDRRRNKASERRGVPRGEVCAERGQRHAPGRQLGHHHNLPSSAEGEPVQLNRGHHRRRAGQGTQTGNNRRQGIQGHNKRSGDKRDARVGHGHERGPPDQDPRRREEDQVYRDGDQPVPTHHLQEHQEGAPRSQRTGVSEGPASVELVNDPLRRSGELGRLSPQLTGGCDGRRGQRGLRRERFRLHGRHNNPSLHPNNKNNYNDHDDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN46</accession>
    <name>A0A1D2MN46_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Neprilysin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_12412</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000834">
        <property type="protein sequence ID" value="ODM94264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN46"/>
    <dbReference type="STRING" id="48709.A0A1D2MN46"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="4">
        <location>
            <begin position="170"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="540" mass="61896" checksum="2DFD309CC167F8F4" modified="2016-11-30" version="1">MMLQSRDMDATCYMKQKKPHVHVTYIIGKPFNDGGKVGLSDSLANAQRSPPTAQRKPQDEFQKHQKELQELQTLARNGGYSNLSSITKYDPQVCYTYDCIEAAKEFMVATNFTVNPCQSGDWLKFTCVRRTMNIEGVDELDDMHQQGQVGYLGSVALGQTLAILESKNLTPILKKAATYYAQCEKWKHGITERDQVDGILKYLDTFGEWPLLTGRNSPGSNFDWKKMMANTMKIAVTYGVAPYLFDIFIEGDDVPLLFTGELGLHLSENEIVEVIKILSKGRRNITTNDKQIKEMTAFMSKLTHPSEDKIQAHPIKNITRHHNFGRNFKLEDFYKGMLAGTRVKITPDTKVSSDIEWLINHVKAVNEADPRVIANILFLQTAAALLTRLTTLTHAEDLPDLEKYRSHGTLDCVRDTYEKFDYAMSHEYIRRYYDHKGTPIMVKLVDNLKYGFVKAIEHVPFLTSQSKVFAIDKSKDIHTFIAAESWVLNEEKLKEYYTNMDVSRDKDFVSNHVAALRFQWAKFLELKDANMYIKSYNPMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNY5</accession>
    <name>A0A1D2MNY5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="17">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_11896</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="17"/>
    <dbReference type="EMBL" id="LJIJ01000750">
        <property type="protein sequence ID" value="ODM94789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MNY5"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058642">
        <property type="entry name" value="BRE1A/B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26052">
        <property type="entry name" value="BRE1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="13 17 18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="15" id="KW-0349">Heme</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="7 15 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="14 17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 17" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 17" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 16 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="20">
        <location>
            <begin position="1294"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="730"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="950"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="501"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="832"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="988"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="1076"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="1156"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="1244"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="970"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM94789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1347" mass="156559" checksum="2192ABDF6B0B474E" modified="2016-11-30" version="1">MRWGGIFRVWYFNKPWVMVASADDCQKLYSSARNLNEKSDEVDITKLSVGDGLYARAGSLYHERRKLLNPGYGISLIRKSIPNINQHSAMLVKTYLKFAESGENVNTYPIMTKAAIRLVWDSLFGKKIADDAPDVSNYINAMFTSSYYHTNRVFKPWLRPDFIFNMTAGSKLAWMGFISSMISPKGRIYWEKKKTFSRRSVEDVSKSSEESENVKGDDWECYLDYLLEQQEKGLLQEKDVLCEFSVFTIGGYETTSIALTNALYLLATYPEHQKKIVEELDSIFGEGFDPSTFQVTMNQVKEMKHLDLCLKEVLRLYPPLSMSPKRTTEDIQLDDGRVIPAGVQLFVFMYWIHRDPKYFPDPEAFIPERFSKESDFYREKATYSYIPFSVLPRSCIGQSYAMVSLKIFLAYLLKAYEWTAVTPRDQLKMSFQYSSHPKNSILKLKPRIMSEGSKRPHSDGDSGNTSNGGPCPSPPPWKKMLLEPISIGRISSLEEMNCKVLKVQHEQIRQRLQQRQKLEEELNKRIEQLENQLRNQTCLSNGINRHWSQLNEDLGILLRKFHTGMDQVDEVVEGGGFSLVSSVAQLTMDHPEELDTILEQQRVKASIFSVVKMLEAFENLRKRREEVTAMLNSGEVGTNALESAVWEANIELESENQRLHALNTHLHQQYQVASLKTKELEQKLIVEEGTKVELHNRIEDLNTEMFKLVCHNEKLVAEVQNLNENYKRLQQQSVSDESKISSQGSSQSRKDRVLSLSQEEEVELLRRENESFQELADKRLSELEDLHRERQEERKELDKLRQEIRYLPERVIVESVEYKCLQSKFSVVYNDNLQLRSVLEEMKQRMTAIKNDHMKRIEQLEIEEETLQNLYKSERLQMAETQSQLEREHEMLRIEFKQSIETSDQPAKVTREMRVLITSLQHLNEQLKAEVQKYRRKYREVYEEVSKLKRRRSETATALEQNGGDGEVPSTSCFGSTSSSSTVVAAPKTSESDVVKELQSKVKRCENEKREMKTLLDMYKGASKEHREKVELMSAERKLREELEELKRLVGTPEKSTKMEERSKEALYHGDSGKRIKCLEEQVHALQRQVTLQKQEEAALLNDMETTGQAFEEMQEQNARLIQELRNKDDANFKLMEEKIKASHIQAARIKEKQLLDELTQSLQKKNEALGEVIKQMEEKEKVLLQTLASREKESLLKSQAVDVFKAKAVEELQKSTDLKLLYEKAESHLNEMRQTVSEKTSLLEMETHKARRLEEEVALMRGKVERLNKLEKTCNADEVYKEEIRIYKDALTCPSCKVNRKDAVLTKCFHVFCHNCIKTRYDTRQRKCPKCNAPFGHNDYHHLYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPM5</accession>
    <name>A0A1D2MPM5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase/endoribonuclease IRE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPM5"/>
    <dbReference type="STRING" id="48709.A0A1D2MPM5"/>
    <dbReference type="OMA" id="FCADESE"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="92"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="340" mass="38499" checksum="E8991353FBE1355E" modified="2016-11-30" version="1" fragment="single">LTSILKPLIRTTMKMNSQNTNAAGILSDNDVTDLEEHSNHPTKKASQFYSLIVKRVKGYTMLMKALNDTNQSGAYSILSKPIPLKHNYFFQYYENKQLGKGKFATVVKGKYGHRDVAVKRLFCADESETLRIDTEIEILKRCGDDHENIVQYFADERSAYFVLIIIELCDMTLKTWVEVDGKKPIQITQWDILNQITCGLQWLHDNRVLHQGLKPENTLLKTHSKKIKISGFGSSGLMKEGEIACAVSTDNVAETIGWDAPEVTQAQNATDDTSKLVSFPSDVYSLGCMFYYVLTDGRHDFGDLKNLEIMENTLENSGVNEILLIKQMISDSTELRTFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPS2</accession>
    <name>A0A1D2MPS2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_11791</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with LYAR and RPL23A. Interacts with the nuclear importin-beta receptor and, at a lower extent, with importin-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000735">
        <property type="protein sequence ID" value="ODM94898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPS2"/>
    <dbReference type="STRING" id="48709.A0A1D2MPS2"/>
    <dbReference type="OMA" id="RTQGFNH"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="210"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="533"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="636"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="579"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="655"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="696"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00065814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM94898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="711" mass="80638" checksum="31376AA058AF14FE" modified="2016-11-30" version="1">MAKDRKPQQKSRSGGKSNHSMNPDRKVSSLKGVANPRDKATIKRLQMYKNFKPKRDRLGKIVKAAPFQTTLPSGSVARIEPSIKWFGNSKTISQGALEKFQEELGKVKKDPYQVVMRATKLPITLLEAKSKQARVHILDTESFDSVFSKKKMRKRPSLHVTELTDLVQMAEKKAETYDATKDKDLVREAPDMWTGPREWVMAAGQSKRIWNELYKVIDSSDVIIQVLDARDPMGTRSPPIEKFLNKDKSYKHLIFVLNKVDLVPTWVTQRWIQILSKEHPTLAFHASITHPFGKGSLISLLRQFGKLHDDKKQISVGFIGYPNTGKSSIINTLKSKKVCKVAPIAGETKVWQYITLMKRIFLIDCPGVVYPYEESDTEKVLKGVVRVELVENPEDYIPTVLSRVKKMYMAKTYKIPDWTDHEDFLTKLAKRTGKLLKGGEPDINAVARMVLNDWQRGKLPYFVVPEGYEKPLTALKPAVEKKRVETVVAENSNELKEDESSVKEGEEEKKETPNITQNLKKIVVGLDYEDEDVKPLTEESGLYDSDNDIKNDEESQDDEDDDDVVEVGSEKASAITIEDSSDDSSDADSETGRLEMYKSLKKRNKGNVAAVKTVSLSTPKTKKPPGGIEVVALPAVKGFKRQAPYSEDDTDDEQVDVKKSKKVPEKLTSKQKRKKERESKQKKVGSNFYEVTNVKNRNRDRKTPKAPNRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR10</accession>
    <name>A0A1D2MR10_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MFS-type transporter SLC18B1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_11153</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000657">
        <property type="protein sequence ID" value="ODM95539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR10"/>
    <dbReference type="STRING" id="48709.A0A1D2MR10"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF26">
        <property type="entry name" value="MFS-TYPE TRANSPORTER SLC18B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10258" checksum="BFDFADC1350129F9" modified="2016-11-30" version="1" fragment="single">FQLNKLAVGAVFILNGGVYAVTAPVWGWICDHTDHQKLITLAGAIFTILGFIFIGPVPYFPYDTTLPMSCVGLALFGLGLAAILVSAFLQVLKDAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR18</accession>
    <name>A0A1D2MR18_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000655">
        <property type="protein sequence ID" value="ODM95550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR18"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="64" mass="7269" checksum="129B883CE12FD6F5" modified="2016-11-30" version="1">MELLLTSDFDPLVFCHLYNNNLGLVFGRYLGSDLMNFSSITEDVEFWICNINGFETACQLGLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSH6</accession>
    <name>A0A1D2MSH6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_10698</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000596">
        <property type="protein sequence ID" value="ODM95983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSH6"/>
    <dbReference type="STRING" id="48709.A0A1D2MSH6"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000130">
        <property type="entry name" value="Spalt-like transcription factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000193">
        <property type="entry name" value="Zinc finger protein 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000690">
        <property type="entry name" value="Zinc finger protein 354C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000110">
        <property type="entry name" value="Zinc finger protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="474"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="644"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="673"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="701"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="729"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="757"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="785"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="814"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="571"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="603"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM95983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="971" mass="111575" checksum="F0DF038375F42181" modified="2016-11-30" version="1">MEMGSAEAALTQMASIPSASSSSYFLQLDPSGHIDILESSLVLSKPDMADETVYEIQLDPYMMDERNVEIINLQQFQHLQTIQQQNAAVPIQSELIEEHHFTSFDPQQIQYHIDDMNLSQILASSNVVVQDAAEEMVPDFTVETEIVTETAPPTSNVLNTCLPLPTGRGIHQNVLHHEPMQIETSIVSEHSGFVIKEENVSDQLPFTQPLSVDEQQMTPVKQEAINITAKSESVASDDSKKPIVDAATIKSEDECEENEFHGFSEPFVPPRVELFSNPSARRTPVPPTVTIYDDEDEDDSINVSQVTNNKTFKSCFLHDGIDPDDELYASYLSRPSTEKTAMCVLCYEWFEGMQELEVHLKDAHQDNMKLYGCKKCGKQFWSRFMRQRHEKQHRYDLKAPLQRYFPKNRPFDHYESDHFLKRLRPAPLTQNYREHLRLIHSQIKSTEYDCIQCGKEFQSEEEYREHYEEKHALQTCLHCRKVFQNSKLLKDHEQEVHGMYRVKKNYPGGAWKLWESWDCEEMKERDNRLVNVSLFHNYNKRKKLDFDEDSVAEKCDTLLAMDCEEVTVSEYEATKPPEKRKSVDKSSSKSIEKKQSSSSSHSDSPKPRKTDLKQSSSKLQDYDKIVFLGIPNNEPVMKREDLPFKCDACKTSFDNDIDLQRHMKTHSIRSMAYMCQYCGRGFATHSNRKEHERIHTGDKPYVCPICSRAFVQISNLKKHIQTHKDKNNLQCSTCGKQFVKESSLILHQRAHSQDRKFRCHICDRAYNYASLLKRHMRIHTGENPYSCEDCGMQFHELVSLHYHRKKVHTGERPHRCDTCGRAFILSSDLKKHLKIHLRDATSGKEKKEGGKSTTSTTIIVNKSNSQLENVPEDMDIGATTKVESFTVENSNEETLNHIDDLSENSEPLMNNETIHEIKPDYSISEGDRVVISETGLLNTTDAANERAETTPDSVIESDNTLIMEESTEAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSI3</accession>
    <name>A0A1D2MSI3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000583">
        <property type="protein sequence ID" value="ODM96079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSI3"/>
    <dbReference type="STRING" id="48709.A0A1D2MSI3"/>
    <dbReference type="OMA" id="ECHIEAQ"/>
    <dbReference type="OrthoDB" id="10255247at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035253">
        <property type="term" value="C:ciliary rootlet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097542">
        <property type="term" value="C:ciliary tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033192">
        <property type="entry name" value="ODAD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="561" mass="64893" checksum="91E0DCABBEA811FE" modified="2016-11-30" version="1">MSYLRSSREGCGRYAKKPNESDENPSFDDDTSIPLQDQIDNLRAKISLKEKYNKALLEEVSETNAGAATMITELTELNQKLREDLQHELRAEQFAVKKALRSYRLFQLAVSEKDAEYVINWLDDKIFDACKTLNEGLHRLRIMQNKLQEAETQVIFLESCPVPGTEPWERKAEDDRIALESAIENTKATRDACKLLNNKYREILVFLKGERGKWPHMMANMERSLNQLKKELAGLEVMLDDANRFRDEAFEKMKLVEEEASANRKQRRGQMNKMKKSVEKALDANTAKYQTKDNPKERTSITGRALDHGTSSTFGQADSTMMQQKVQEMKVKQAQVLDYEERANKIVDIMRVPDLRYCPKRLKTVRKVTEVLNEELALKEEMRQMQLILEHFRYTGIQEEEEFAGKCVEKEQEIAKKEDEVQHKEKERHLKGTTACDLRFSLLSVEEMFNQGKKKPLGRKQEDIRLMMKKISEKVQGLVDSVEGLRKEFPEGSQPQRSYAAYVKLNVHARLVRVGGAEEVEVDDDSDPDADLIDSKVPNREELKSRSDKFYAQALLRKGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSJ7</accession>
    <name>A0A1D2MSJ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc transporter ZIP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000623">
        <property type="protein sequence ID" value="ODM95764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSJ7"/>
    <dbReference type="STRING" id="48709.A0A1D2MSJ7"/>
    <dbReference type="OMA" id="EDPPILM"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF203">
        <property type="entry name" value="FI18611P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="408" mass="44702" checksum="6BB13419FEBF2E0C" modified="2016-11-30" version="1">MGISVEKWLVMAVLTVLSIFLGLLPYILVRHTKSMLHTDSTRYKVILTILSCFGAGVLFSTSFLHLLPEVRESFNEIPEVWTTFDDHFPVAEMVVICGFCLIYIVEEIAHFIMVDGHHGHHHHMNTVARHNSIAHGLPIPNVKGAVTTSRSAASIAQNGPSICITMSDSSNDLTMRVDGKSSIDCTSETEECPDDDKSFTSSLRTFLALIALSFHAIVEGVAVGLQDSTDVWVMFGAVASHKFVISFCMGMELVASQTKIATYISSIAFFAILSPVGIIIGSLLSSNSTNNLPVTVIEVNTTYIPLKKTSSDTLLFFKVMHKYPSSRAALTFGIACGTLLYVVFFEILNRERDRKSYSMSSSRAIGFIQFVALVVGLVSMGCLLTLTHGHNSEDSHDHGDDHDPGHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSZ7</accession>
    <name>A0A1D2MSZ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000574">
        <property type="protein sequence ID" value="ODM96136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSZ7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904505" evidence="1">
        <location>
            <begin position="21"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="310" mass="36259" checksum="1B42DCB8C63BCE1C" modified="2016-11-30" version="1">MRFTLPIIFVLLACATAGLGLKLKEENGIDKAKLKSLSPSQKLVFLAASHFPQFSALKDLTFRDLFSSDDMPWIDYMFVDIRNFFIQSIKVNENQGGLPELDWAYTVFNDYWFVFNITVTYKTRETQMVGQKTTTSVNEITPNSFKNSFYVPSYIWRSPGALFQVYENDEGYSLNAEDWYLGINGLTLNTSFNYEYVPDLGIQISNLTIDFDMNYWRTNCEYIYWMHPNGTREDYESIKWDYEDILLDEWKYSQEDYLDALQFRINCVLSNNLNNPDRCDLGGGYVNREYFRMNVLQLIETIGLASLDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTT4</accession>
    <name>A0A1D2MTT4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10374</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Component of the THO subcomplex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7. The THO subcomplex interacts with DDX39B to form the THO-DDX39B complex which multimerizes into a 28-subunit tetrameric assembly. Component of the transcription/export (TREX) complex at least composed of ALYREF/THOC4, DDX39B, SARNP/CIP29, CHTOP and the THO subcomplex; in the complex interacts with THOC1, THOC3, THOC5, THOC7 and DDX39B. TREX seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with POLDIP3 and ZC3H11A.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000554">
        <property type="protein sequence ID" value="ODM96311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MTT4"/>
    <dbReference type="OMA" id="QERWTCI"/>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="10">
        <location>
            <begin position="134"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="10">
        <location>
            <begin position="420"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="9">
        <location>
            <begin position="561"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="8">
        <location>
            <begin position="883"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1204"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="931"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1204"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1241"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1259"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1301"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1333"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1344"/>
            <end position="1372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1382" mass="157229" checksum="7F305060D15B8289" modified="2016-11-30" version="1">MSPPPRKRGRGEKAVASSSIILANITKHLKKDRTVGAQPRWITSNFWTDWDRGSKKTFVAELKKYVKLLDSHDTSSKSTDHKSSTNGVSEDTNAVAATLEEYKSAVYLLIRASKGKRYTTLARACNDFLGFVYMERLDLENLQDTGAVNNKKAFSTKVIRTKTRIYYKQQKFNLFREESEGYSKVVSELCNPSSDNSVSYMARVIPCLVGRFNLDPNRVIDLVLEAFECQPNCKFFIPLLQSLRPSPETVCEIIGFKLQGQDRPPESLFVMIALLLQNNVIELDGIYSWLTPDDRVIHKEWDRELLDAREYARKSMIVSINKDKETDENDEMNSAEDRYLDNQKFLLIEALLSTGGWPFVKKLMDRLPEFCLISKRRIALKLIHFVEFMIQPLYATVHETTDRLGKRPITQLKDMSMNRKQIRNWSDLEQEMDIVLSIGPYVHFEPVLMYKLLRIMRTYLKQMKHSPPTDLYYKFLTVLDEVILPGLCFLDANCCIAQEIWAVMDYYPYQHRYRLYGSWKSEAILLLHPSLLRKRVDVLKKVKHLMRRISKENVKPMGRQLGKLSHSMPAVIFDYVLSQIQLFDNLISPVIDALKFLTTLSYDVLSYCLLEALSPGQSSNSASLSVMLMPNRPRTKHDGSTISPWLQSLCSFTGAICKKYTIELVPLLQYVANQLKAKQSLDLLLLKEIVQKMSNIEAAEEITNEQLDALAGGDILRAEAGYFGQVHASKKSASRLRDASSVNDLAVTLCILMAQQRHGIVYDDSNAIHTKLVGKLYDQCQDTLVQFGTFLSSSSSTEEYAKKIPSIDKLFLEYHVSADASFFLWRPLLSNAIIAKYDELRRAEKSHKSMSASQRQEKYALAANHILSPLISLVSSILPQKTWEDITPQFYVTFWSLTLFDLHVPSDSYAVQISRIKQSAASFAENKDMASSKLKKEQDRCNSLIEKLQEEERRQRDHVDRVMTKLKQEKDLWFAPRTAKSAKNETVTAFLQLCLFPRCIFTAPDALYCAHFVNIIHSLATQNFSTLICYDRIFCDIIYTVTSCTENEASRYGRFLCALLGTVMRWHGNKAVFEKECARFPGFVTKFRASNSSSAESSDHVDYENFRHVCHKWHYKITKCVIVCLESKDYIQIRNSLIVLKEILPYFPKVTNLGAAVERWVERVRVDEKDKRQDLFALATSYIGQLKARWNTLVAEEDFHEKVISPEKPVKRPAKDDSSGSSSTTKDAKSKPIPRTEPMEVSTTDSAPSKSDAPATNPSGGSKTSKPTSTESAASSPVVTKKEPVEEAPVPKPPKASSSSESRRETSKVREPTESRSENVVEKSSKSEKRSSSSRPESHSSSSSKKESQEVKVKKETSSSSDRRTSDSDRSRGMTKASMQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU44</accession>
    <name>A0A1D2MU44_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinetochore-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000539">
        <property type="protein sequence ID" value="ODM96452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MU44"/>
    <dbReference type="OMA" id="EEWPVPW"/>
    <dbReference type="OrthoDB" id="343783at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005828">
        <property type="term" value="C:kinetochore microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903394">
        <property type="term" value="P:protein localization to kinetochore involved in kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055403">
        <property type="entry name" value="ARM_KNTC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052802">
        <property type="entry name" value="KNTC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019527">
        <property type="entry name" value="RZZ-complex_KNTC1/ROD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15688">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15688:SF1">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24520">
        <property type="entry name" value="ARM_KNTC1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10493">
        <property type="entry name" value="Rod_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KNTC1 first ARM-repeats" evidence="2">
        <location>
            <begin position="486"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="RZZ complex subunit KNTC1/ROD C-terminal" evidence="1">
        <location>
            <begin position="1339"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1425" mass="162449" checksum="045CC646BB82A5F3" modified="2016-11-30" version="1" fragment="single">HPSAIMVQETSICDSPDNKCQLDIKPLAGVAVNDAAARLQSRGDASDDNIFEILPRFCISPEEGNCKWVRKHSETGGGNAVLQVVAAAGSSDVTAIAMGCDLVVFERDKDKPVKKMNFNDHIDFVLWRRSILLIGLKLDNDAKAEEPFFVDAFIHSNPDPTKLDVIVVSRCGQVGRFPDISLSDGSLDNTHDQNISVDIDLGTVKALTRKLNPTSKIVCATSSSRHELTVVEENGRISVFDLGGSKQVVPSIFVVDNLFMNLCMPLNKLGRVVPKKVMSFEGVLFVLFTDGNLQLFLSGSMFPSNSLNLLSESQRVHDFTLVMNNEGIVKLWVLYGSQPSGCENYVGIFSGTAFCPEFLFKLPLLQNSENYSELAFPRNVSPFEEPFTIIEMTANNVQLYHMLETSTDATMQKLISRGQYSKAEELALAYDKDLDIVRKAEARDILNKITTGHLKTEGQVPGRDTDYKIWSSLGFFSFKKILVWLDSLYVNLLCVLRSIKDAEFICNFHSHSKLPKIEWIKEIIELGKSRVYECTDHTVSNLLLLAVNRLHTFDLVYPNGTTMEWYSMISDDNNMFLQSIKFLDQGNYDKCEKIWRRHSEEFVPSITLAEFLPFFNSLFEHQLQTRNSVQLLKTILPFAVGKVAKSTLNDQLKESANVGTKELNVLLSLILRQVSKMETHVSWPSNALSFVKVLSSVIKDQIKYCGGSEGSELESPETIKLIMQKISTNLDHLEVVLGELADLKSRHSIRIAFQEYSTNDIAAVVNHLLYNLLSRDEVESFVSKFLRPYAERKNCNIDFLFAAHIKSVLLDIPYFIQSINIPHEERIVCLVHLFESHKLKLQSVLHISEEWPVPWSIGIDKMVQEILESCPRNGGGDQECMRLYESIRIMRKQVPYRCVLNKYKLIGTKLLKTRCNITMALLKILKLKKPGYYEDCKELLNNIPGIASMDDFRLDYLDLILKMYDPEVSEEELIECHQIDSKFGKALLHRVFLELEHFETEDALNNLYTQEEQERFKTIYSLQAFNSKDQQMYITSKLKRFLPSIPLDVVYSSGYPYCLVTHVFSDSKTPSKILEDCKTISRITQSYFADILIALGFYYSQASVPGNQGATLWQIVEQIVKNPLSNDINNSFENHELLKNACSNICTVLMFQCPSYSLGQMDILQQFLCRISDSFDKLCEDIGQMLCYLKIFLVMKEQEIPLEQEFMEVFKWLSGSPIKWEVVKNRLAEIGETLLKFGETDINFSVFRAVRRHLIGFLARVESNGGLFNHYSKIVEEINGIYEDLSNRTRSIVEDEPDMKIRRLVDSLNKAGVRVNSYALKMRNKVKLLERLISMKNYALAAQLAMTFSFYENLKCWSSILRGFMSTGDLIELRKVLLGVRTIRTLWMLPEFAEAWKRVAETDSQFYDMCPIPLDSFCKQEKISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUK2</accession>
    <name>A0A1D2MUK2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000505">
        <property type="protein sequence ID" value="ODM96770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUK2"/>
    <dbReference type="OMA" id="MHAPAIP"/>
    <dbReference type="OrthoDB" id="8279873at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904584" evidence="1">
        <location>
            <begin position="23"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="189" mass="21124" checksum="51C8A0EA7646F15C" modified="2016-11-30" version="1">MGHSKIIILFLVLLSVFLSSFSKPTKKYRYDAEFLDSEIQRIRSGRAEVLEPVWTVTKSTKKPAVVDGDGGVTKTGVEKGEAKLNTSSSYEGSSEEYEDSGAYYGSSEEIDFTCAQGKGWHIRGQRCVPVNCPGGPAERDFNTGECLYSSQPKGRFNKPFTQWNDLNHVYRSSPMSTHFVRSMILMRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUV8</accession>
    <name>A0A1D2MUV8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000510">
        <property type="protein sequence ID" value="ODM96701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUV8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="35139" checksum="21D404D750845CAA" modified="2016-11-30" version="1" fragment="single">MYTCPTSDGACALLLIAIWVEVAVDYWAYVIFTAHSLFAVGIFHYTGKELWARLKHEPIKKGTVNWVLVLVTFVTACLFPIVYGYNAKVVGQPVRESNVVEDALLVYACTLVLLTMFYISSLHHEHSVLEFHLTILSIWLQLGCILVLTTWTSFFNDKQINMKAHIIFGVDVAFSLALFCYTGQEICMKCRRKPTNLKAVKRVCGLCTLGTMLLICGVYYYNTLGLGQHIMQLNKVFWSTTVVYIFSILLFCLVLRKNPMQEGAVPLSKTEDDDAEKGNETDRKLSQVTVNVQDTEAIMEDTVKPNNIDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVL6</accession>
    <name>A0A1D2MVL6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endothelin-converting enzyme 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000469">
        <property type="protein sequence ID" value="ODM97140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVL6"/>
    <dbReference type="STRING" id="48709.A0A1D2MVL6"/>
    <dbReference type="OMA" id="HCELENG"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="22686" checksum="960DB96F68A2B9A4" modified="2016-11-30" version="1">MIIPLGILRYPMFVEEYPMYLNFANLGVVISHEITHGFDHQGRHYDKDGNFTTTWWPDDVVSAFKTQAICFADQYGKFEMPMVETNVDGNETLADNVCDNAALRISWLGYQLWMEDFGSEQKLPGVDYTISQVFYTLYAQIWCEVLSKEGILQYIGDSHAPGQFRTWGVAQNNKHFGEVFQCPVGSPMNPKDKCVLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVW3</accession>
    <name>A0A1D2MVW3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Target of rapamycin complex subunit lst8</fullName>
            <shortName evidence="7">TORC subunit lst8</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_09460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of TORC1 complex. Part of the TORC2 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000461">
        <property type="protein sequence ID" value="ODM97220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVW3"/>
    <dbReference type="STRING" id="48709.A0A1D2MVW3"/>
    <dbReference type="OMA" id="VQRNYKH"/>
    <dbReference type="OrthoDB" id="400at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051897">
        <property type="term" value="P:positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032535">
        <property type="term" value="P:regulation of cellular component size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000505">
        <property type="entry name" value="Blast:Protein LST8 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="132"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="176"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="320"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="369" mass="40033" checksum="700E188B6EABD0EA" modified="2016-11-30" version="1">MKMVSPVVEEGGGSPEDDEVATVATTNATGTTTGTSSNPGSLTTSSTGGGSSINGVPNATALETVLATAGYDHTIKLWQIHTALCVKTFQHPDSQVNDLCITPDRRLIAAAGFQHVRLYDIQGTTQSPTLNFEGIQKNVTAIGFNTDAQWMYTGGEDFNARIWDLRVSNPTCQKLFQTHSSPITSIALHPNNVELIVGDHSGTIHVWDLRNDRTEQLIPDQTSSVPVQHVAIDANGKFLAAVNNKGDCYVWSLDADGDGDHLRLSPFHRMKAHKRYALKCCFSPDSNFLATTSADQTCKIWRTSDFSLVADLHCSGQRWVWGAAFTGDSQYVLTASSDNLARLWSVESGQAKREYNGHQKPVTCVCVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWV1</accession>
    <name>A0A1D2MWV1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000434">
        <property type="protein sequence ID" value="ODM97537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWV1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="539"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="635" mass="71399" checksum="8BD0FA03F651BEDC" modified="2016-11-30" version="1">MALQQHGITIPQLETWWAKTRLSRGPRVFPICITKISGKSYPPSLSVWGPILDDIALNDIRFYDKSIHSWEATNSTSAISDVDFTFVVQKSEKDEKNFLLYHWVNLHIRTRVKTQGLFIQAITGPLGLPGGEFDINVPCSLSSAHSEGQLVHPCTVAPKSSYTWPNIYAINIPSKSDHFSVRFRWDEAQCLYTGIIQFIMITTGSFRPDDYEIKLSRFYYTNYDVQKTVLTGMSTKPYLGFKGSYECDSDSRMKYSRDHPRIIPSMEFDKCLTKGVGLDSSSSTCPPGPFVCRTLWRTDRTWWNFRNDYGNILKKFKIYTDCCELGKIPFVPTTTTISTTTTSTTTPTTTSTTTPTTNATTARTTTKKIRLYHNLTSEEKVEVKLSDRAHEAEAASRVTHGDLCILVYLLFIPLANHIARFYKDFPDFKNIGLGFWIIAHTILHSVSLIMTWLSFGLVTGTGENKLGDVSASHFSLGSVVLFLQHMVICSSLKLLGVLTPSKAFPYVSMHSLGARFSYGFSILTIVFSNAVLIKKLLAIALVFLQLMASFCTAFVEYKQDKLLGITIHRAWCPVLQRVSSDFGERTPYMRVKTVLLVMVSGWLGSCSVSIYKTRVTKLVMCLILLKSQSECANVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWV2</accession>
    <name>A0A1D2MWV2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000469">
        <property type="protein sequence ID" value="ODM97145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWV2"/>
    <dbReference type="STRING" id="48709.A0A1D2MWV2"/>
    <dbReference type="OMA" id="CIRVEDG"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF6">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="1">
        <location>
            <begin position="44"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="24197" checksum="DB6C70DF4B3B700F" modified="2016-11-30" version="1">MYIDAGPSSGNIKINIVTSGESYARKWRIKISQVPCNAQYRAGDSCLQYFTGMSGRIKSFNYGDPTMMGPEYGMQLSAQEYTTCVRAEEGFCGIVYVPCKDSAEFKEAFQISSTSQNMSIPQRTMTGAEQCPSDWLGIACATDTGREQQTDGSSCVDRVCGGTFTSLSGSTSHAPVYSFSRPFNLRIHFNDFEMSDPRAPDELNRGFCLDFVQQPCPQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWZ0</accession>
    <name>A0A1D2MWZ0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fructose-2,6-bisphosphatase TIGAR</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">TP53-induced glycolysis and apoptosis regulator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09102</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <dbReference type="EC" id="3.1.3.46"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000430">
        <property type="protein sequence ID" value="ODM97577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWZ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MWZ0"/>
    <dbReference type="OMA" id="ISAHVAY"/>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="113"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="33235" checksum="EFD3C4E8EA75984D" modified="2016-11-30" version="1">MHNCRQTQTKLQRLTFGQLTMPSTENVTLTLYLVRHGECQGNVAQVALEPFADPLTDVGRAQAKLLGECLQDVEFTRAYASDYPRTFETAKIILEQSKATKVKTVNPEKRIRERDYTGLLGKRAADCIDMMMGMMRTGTKYLECQIPNSETTTQFEDRIINFLSELIQECKTSQNSEETVLAVAHGLTNQRLMILLNNRAQDFGIEKWTRNLFSEKLMRNTTFHKIVFEIPRIWSEISAHVAYPHSEKHVEGNTAKSVEKNVRDQDNYAFLDNADLIYAESETVHYCKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX10</accession>
    <name>A0A1D2MX10_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000429">
        <property type="protein sequence ID" value="ODM97583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX10"/>
    <dbReference type="OrthoDB" id="8196656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="74" mass="8045" checksum="87DEDE690291DDE9" modified="2016-11-30" version="1" fragment="single">MQISPPNQVDVESKGSTGGSRPPSRVRVTFFESEKPLAVSSPESDIIDFDLSKMTIHGSPTAVDHSSPTYNRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYE5</accession>
    <name>A0A1D2MYE5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-glucuronosyltransferase 2B20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_08659</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000389">
        <property type="protein sequence ID" value="ODM98012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYE5"/>
    <dbReference type="STRING" id="48709.A0A1D2MYE5"/>
    <dbReference type="OMA" id="INLAPAM"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000050">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904732" evidence="4">
        <location>
            <begin position="25"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM98012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="500" mass="56332" checksum="AE6CF9B36381A7A7" modified="2016-11-30" version="1">MKMFRMTIKIVAVFLLSSISISESANILFLTPIATKSHLNIFNSLINGLAERDHNITVVAPLKMKTPLPNVREISPIPFEIMKTAVSSGNPFERRKEGKSGLFLSWNSTFMEVGSDMMYRNEEIKELIKGGPGSFDLIIVNAFMNHFTLGIVHELQAPHMYVITMPAMNVQVSKFGLYFPPSFVPCSFAAFSDRMNFKERILNFLAEYFMLAITGTVWVPYLSKMYQDHLGSHVPNADEIDRNVSLLLMNTHFSLTYPRPLLPDVVEVGGLHTRESKPLPTDLDEFLSGAKDGFILFSLGSIVQPKDMPVETSTKFLNVFSKLKQRVIWKWDGELPGKIPSNVKLAKWLPQQDILGHKNIKIFITHGGLLSTQEAVFHGVPLIGFPFFADQDLNIIQAEKAGFALSLEINEFTEEMLEDAINKVLTNDSYSKRAKHLSTVFRDRPLSPLQTAIYWVEYIIKHKGAEHLKSAGRDLNFAAYHSIDLCASGSKKELSKKKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZL5</accession>
    <name>A0A1D2MZL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000382">
        <property type="protein sequence ID" value="ODM98095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZL5"/>
    <dbReference type="OMA" id="EWIDAYV"/>
    <dbReference type="OrthoDB" id="10598230at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="25600" checksum="2EFBE82FBD173EAB" modified="2016-11-30" version="1">MALPTAKRPKIVEDELQEELEAKRRARLIVKVDKIKIFMDSMKAWYKGLKSAAKLNMTHTILKRKAIYICYHNRIVYDRLPLTWVKQLQQEVGLKFHPKSSIRLLAKIRAANPEPESSIPAKKDEDVPINRRKFKKILDLSSELPPPEWIDAYVKGIVLPRQLKIYSAPDLNIIYYDYEPKLVDSSGNEYKIPNQPRHNLDALVPRPHKKAKKRVHFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Q5</accession>
    <name>A0A1D2N1Q5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000293">
        <property type="protein sequence ID" value="ODM99227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Q5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="17746" checksum="2D9D7842A150C167" modified="2016-11-30" version="1">MLPKNVIGMTRILFRKFYIVTILVVGVTFWAFVTHLAPQVTLSSKEQVQPSKQNHNYHKVLSDTLNEIEGDIASQKIYSSILLSKLREKYTNNEKREGDNSAPISDNKHLNQGSSVIKVQDPEKLRQLQHELQQEAHNGEVHSLELDKDGNLKACI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1R5</accession>
    <name>A0A1D2N1R5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="17 18">CDP-diacylglycerol--inositol 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="5 18">2.7.8.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_07453</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11580"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18 19">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.11" evidence="5 18"/>
    <dbReference type="EMBL" id="LJIJ01000293">
        <property type="protein sequence ID" value="ODM99237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1R5"/>
    <dbReference type="STRING" id="48709.A0A1D2N1R5"/>
    <dbReference type="OMA" id="AQTYSEN"/>
    <dbReference type="OrthoDB" id="10251079at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000003">
        <property type="entry name" value="CDP-diacylglycerol--inositol 3-phosphatidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014387">
        <property type="entry name" value="CDP_diag_ino_3_P_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000848">
        <property type="entry name" value="CDP_diag_ino_3_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 18" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 18" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 18 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 18" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="16 18" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00070582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR000848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM99237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="23718" checksum="8EB3B2A246E620F1" modified="2016-11-30" version="1">MVEENVFLFIPNIIGYARIALAVLACMFMRSCPGSAFFCYLTSALLDAVDGHAARHFNQSTKFGAMLDQLTDRCGTACLMMCLAAFYPSYAFFFQMSLVVDIGMHWIHLHTSLLQGQSSHKFIPENDPYLLRLYYTNKTVLFGMCSGNEIFYMTMYLLHFYDSYLLIFIAVLSFPIAVAKWLMAILQGTTAAKNLAGIDAAERLAAKGAKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1U2</accession>
    <name>A0A1D2N1U2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000292">
        <property type="protein sequence ID" value="ODM99239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1U2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="8225" checksum="9FEE0135DEC05A43" modified="2016-11-30" version="1">MIPVSSDTYTLPALNWELVSGVDEVLAWGHVNYKTVLQATVKVELAVALDVGLELGGPTYQANETIVHSIIICISSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Z5</accession>
    <name>A0A1D2N1Z5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lymphokine-activated killer T-cell-originated protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000289">
        <property type="protein sequence ID" value="ODM99289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Z5"/>
    <dbReference type="STRING" id="48709.A0A1D2N1Z5"/>
    <dbReference type="OMA" id="MIMDIAH"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43289:SF14">
        <property type="entry name" value="LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43289">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="71"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="388" mass="42835" checksum="C5D6EEC3695454C6" modified="2016-11-30" version="1">MSSTPTESKTPSSGDEMSPSPTCLLTPTSVSSGNGSSSMCTPKQNPIRLRALENLMKERVSKSPQLQIPASPVMERLGYGTGVGVFLLERSPRPNGDASSPWAIKKTMRMKEDDEVITARLEYEADILRQLCHPNIIGYRAFGKTTSPDAAFLALEKASKSLSDLIEDRVEEVMMIENCDEEAPFPAKKIEKVAIDVGKALTYLHDEMKMVHGDVKSANVLVFGDFETIKICDFGVARKLNAKGEVEGNYVGTEIWNALEVITVKRGGVKKFPITHKADMYPFGLTIFEMISLKPPHLSSAEDSYLETSQTDNATDDSVVVLEQSFDEEAYELALSRYIGTRPLLPDIDFDSSYNHILGVFYCCTEEDPSRRPDAKDVVAALEIDAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N262</accession>
    <name>A0A1D2N262_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E2/E3 hybrid ubiquitin-protein ligase UBE2O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07334</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000286">
        <property type="protein sequence ID" value="ODM99348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N262"/>
    <dbReference type="STRING" id="48709.A0A1D2N262"/>
    <dbReference type="OMA" id="APETHRY"/>
    <dbReference type="OrthoDB" id="47801at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057735">
        <property type="entry name" value="UBE2O-like_tSH3-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23046">
        <property type="entry name" value="tSH3-B_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="632"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="928"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="949"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="971"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="984" mass="109998" checksum="B4BD50F00B35455D" modified="2016-11-30" version="1">MFFVITKIIKIGVDGEEVKSVVKPEILKSEQYAIITEVNENESKSKLSESSVGSVEVESVTNTAVQPTLPSHIPKRFYPGDVVVQKVDAIVSSKEWQPFFGTVLKPAPGSEMSKNPDKGSSGEFHVHWDYSNRIATAKASEVALVDRILLRGQRVQNAKGQIGTVVDYSVSATVQINGTNYIVERVPLQRLRPISPFVRGQEVLHNGWVGVVTCIKRNVWFRMDGGSIFSVEATEKDGFTRADPFWGLGVACPGMRTRLPTTALKTAKWITSPHRFFSKWLPLHYFYGWAYSTIIRTDVLQLEVKWLQPSDMTNAASQAVPMPNPIVNQDQLKQILVIGTPSTETVGINSVRKLRVWSKDEISNYDVWIAEFRKKFLDGDDASTYTTIKPNADSQMKNLDGVTEKLPAVKIPLISPTIDDGEFPMGLVVSPTDKDGARGEKYGIVMESNDLAKSRSRKVNVRWIVNGNDDGIFEESVFNIRPHKAYSLYQRGAIVFPRDPSTSEFPSGVVIDVNINHGKMVIIRSSNGVQDEVFPHEVLALHKRCHWSFFTRSWIIDDLVPPPYQLEMEYDPIKKLVDVSEQKLNVLDIGNNNVEDPSNFATLWDEPSFELLGFAPETHRYYNSKSKSFGKGFAQKVEKELESLRDKFNVPEGIWIRCYENRLDLLSVLMVGPTKSPYEDGLFLFDVQLQADFPASRPAVHYVSYTLEVHPFLSFDGNVCVSAIPWDLPEGAEAPSSYIALFLHKLQAIIFTPTPFFSTIQKKPEESPERTLIKSRLYNQGVLIRVLDSSWNMLQKPHAPWERNIRNHFASIVPEKLFAIEKLLNLPNTAEATEGDEDIPDYPLLPVPEGFSIAAQSRIEMFKKLISGSHNLPTVQIVSLTDTTADTESHVVKEVGVEGSRCLTPIAEITEPSSTSTFGGKHSAISVHSDDAAEQPPSLDSLKNVKQGTNNNKNKKMVVVTTASSGELESEPDHEHLELKASVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3H2</accession>
    <name>A0A1D2N3H2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bloom syndrome protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000279">
        <property type="protein sequence ID" value="ODM99475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3H2"/>
    <dbReference type="STRING" id="48709.A0A1D2N3H2"/>
    <dbReference type="OMA" id="IMCKEIA"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="2">
        <location>
            <begin position="61"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="272" mass="29901" checksum="C8B4AF5CD64BC056" modified="2016-11-30" version="1" fragment="single">EEIIQSRDKMMTYAYIKLGPKAEKVLSGFTKVQFPVSKPKEKAPTNAAEKSLNLELEGTIGALQKACYRDLIIMCKEIAAGMGVTQWTTIMSAQALRAMSVAMPETPNEMLQLPGVTKANFDKYGAKLLEITVKSSADRFTLLAEEQDKIEDFDSQPRPSTSKGFNSANTSVAKKRAAKAPHDDGWINMDSQESQYFNNARAKGKAAPKKKAFTFGATKKYKRTSTSTKTARKSKFSPKKTTAGRKVTSTATTKYGASNSRDIGFMPMPIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3X4</accession>
    <name>A0A1D2N3X4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="14">1.14.11.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_06699</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:42032"/>
            <dbReference type="Rhea" id="RHEA-COMP:9785"/>
            <dbReference type="Rhea" id="RHEA-COMP:9787"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
            <dbReference type="EC" id="1.14.11.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="14">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ROX family. NO66 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.27" evidence="14"/>
    <dbReference type="EMBL" id="LJIJ01000242">
        <property type="protein sequence ID" value="ODM99969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3X4"/>
    <dbReference type="STRING" id="48709.A0A1D2N3X4"/>
    <dbReference type="OrthoDB" id="425950at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140680">
        <property type="term" value="F:histone H3K36me/H3K36me2 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032453">
        <property type="term" value="F:histone H3K4 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000013">
        <property type="entry name" value="Ribosomal oxygenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.40:FF:000001">
        <property type="entry name" value="ribosomal oxygenase 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1500">
        <property type="entry name" value="JmjC domain-containing ribosomal oxygenase (ROX), dimer domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049043">
        <property type="entry name" value="WHD_RIOX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21233">
        <property type="entry name" value="WHD_RIOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 14" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 14" id="KW-0408">Iron</keyword>
    <keyword evidence="4 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="JmjC" evidence="16">
        <location>
            <begin position="420"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="70"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="770"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="771"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="807"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="832"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="864"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="882"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM99969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="893" mass="100297" checksum="8E84D9ACAC6FDA1D" modified="2016-11-30" version="1">MKDPTKSPDPRLVSAYSVYKGLVPGLKTYQDTSQPTPTSQKKKAGKKNRKRESDDIKMALKAEEAKALLEEVGANGSSPQKKGIEKSNGAANGNAEGKKKDKTKRATEINEVASTTTITESTDEGSKRKKKRKKNKKRKDTTNEESQEQQKENSTSVLDSTVCMSDDDDAPPLKARKLTKDLVPNPLASSVGQKKKKRDSNQKADVNTSQSLGGAAADTSTSSPKKKSKKKKNKKGSQITDSRAGNRVADEFDGLEMEVPSTTTPAAGKSKVDKKQNKQKALALTSSKSTPKKSPYEVTSSAPPPEPRSVFNSKRIEDSVEHGKMALEWVIHPVSSEEFMKDYFEKKPLLIKRKHEDCANFYRGILTTQLFDDILRRNCVKYTVNVDITSYTDGVRETLSENMQGRVRPAVVWDYYNNGCSIRMLNPQSFIQPLWRLNSSLQEWFGSFVGANMYLTPPDSQGFAPHYDDIDAFILQVEGKKQWKLYAPRKENEKLPRFSSGNFSEAKDKLGEPILDVVLEEGDLLYFPRGVIHQAKTVDSEHSLHLTLSFNQVNTFGDLLKHHMNHALEKLMANDVSFRQGLPNDYMSFMGIAHENTTDKENAQKRKTFSKKIEQLVTKLAKEPADFAADAMGKKFIWDSLPPFLSSKERETCVVEDGEFMQEGRVFNRVEFGPEVEVKLLRKNCVRLVVEEGVLRLYYSTENSLVYHDEEAQFLELTVELAPAINHLISQYPNFTKIEDLPLSSDDISQKIQVISDLWERSLIFTKEPLEPCDVDEVDSDDMNDDEQDDDDDDIESVNLSDLPVENGEDGSDGSDESDDDFYDTSAYGLVDDSDDEDGEGSEEFSNDEVDDGQADQDGIVEFPESDDEEEEVDDVDKFFEMDEDDDSSVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N450</accession>
    <name>A0A1D2N450_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PR domain zinc finger protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000253">
        <property type="protein sequence ID" value="ODM99824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N450"/>
    <dbReference type="STRING" id="48709.A0A1D2N450"/>
    <dbReference type="OMA" id="MESHEFF"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="447"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="631" mass="68732" checksum="546C6BB4154B2177" modified="2016-11-30" version="1">MSCCGCASRVLNLQSEIRSWKSKLGDEKREKKMILRWIMAVFGYDIQVEIDRETHGVRVEATENKEGMAKALVKLGIGRGGGVGDGEVNQKMVMELKMESHEFFEPFEDPYEVPEFPILEINSMSTQQPIVNTGIHYGHLQHHSSNPQTLSTITTPIEATPTILSTGPSDQEVLYLAGNFEEGATIEGSNGQSYILVRASEGDEMSMQFDYSNVVKEEVIDDGNLYYRLATTTPMGIESAINYLPVTQTHSSLSSVVTHPHAVPLVREADSDQMETEIDVMTETTIESPIESPAPLRKKATSSAKVIGQGSTKALKKQKSSTSEMNVKIKNVHSKSVPTTKASTSSSSSGKHKNLYSPPPPEGHSESSKPKSKQPEPTNSASKKGVFEFGLTLREKAEIYVIQKAKDAVEKVSNGYRCTVCEENRYIYSNHDTAVAHTKTHFESKKYRCEFCNELFSIQRELLKHRKTMHPKPKGAVTSISSRLTSQARASRKSNESELSTTVKPACTTADGSTSPNSQTRTIIVQAPFGKSLSGGPISISSDVLAALLGSNSSTITVASTNATQPKSVAIPVVTKVPRIIMTTGSGSNNNSFCVYPPERRATDSVIAATKSQSVSLAAFSNAQKDKSTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N535</accession>
    <name>A0A1D2N535_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acyl-aliphatic-L-amino acid amidohydrolase</fullName>
            <ecNumber evidence="3">3.5.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-acyl-L-amino-acid amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_06302</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.14" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000211">
        <property type="protein sequence ID" value="ODN00378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N535"/>
    <dbReference type="STRING" id="48709.A0A1D2N535"/>
    <dbReference type="OMA" id="CFAVTDC"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004046">
        <property type="term" value="F:aminoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052083">
        <property type="entry name" value="Aminoacylase-1_M20A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010159">
        <property type="entry name" value="N-acyl_aa_amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01880">
        <property type="entry name" value="Ac-peptdase-euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45892">
        <property type="entry name" value="AMINOACYLASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45892:SF1">
        <property type="entry name" value="AMINOACYLASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036696">
        <property type="entry name" value="ACY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905048" description="N-acyl-aliphatic-L-amino acid amidohydrolase" evidence="11">
        <location>
            <begin position="23"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="12">
        <location>
            <begin position="212"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036696-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR036696-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="437" mass="49295" checksum="EEE66177D5B35B56" modified="2016-11-30" version="1">MAVTKYPLIIFTIAYLTRTAFTFPSSLQEDPAVTKLRTYLRFRSAHPDPDSGYEQAIPWLEQYAEELGLEFNFLDLDEPNRFAVWMTWRGSDPSLKSVLLNSHMDVVAAEPDKWEYHPFEAYKDAEGNIFGRGASDMKSATIAELEAIRKLKTSGFQPLRTIHLTVMPDEELGGVRGMIPFVKTDEFKNLNVGINIDEGFPIDSENMVHITYAEKSIWQFNITARGAAGHASTLPEYTAGQRLQVVIDKLLAYRESELQKLQNPDVTVDQLTSLNLVRLGGGIGDNTIPNEVWASFDMRIWLLPNWNFTDVENMILNITEEARLGSTPNEVTLNFILKSMEAGRTTPDDSNVWWTVVQDSCREMNITCPPNVLSAATDGRYVRSMDIPVFGICPFPNTPNTAHQDNEFINEANFLKGIERYATLIQKLAVLPGNLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N551</accession>
    <name>A0A1D2N551_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Xaa-Pro aminopeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_06319</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000212">
        <property type="protein sequence ID" value="ODN00352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N551"/>
    <dbReference type="STRING" id="48709.A0A1D2N551"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000003">
        <property type="entry name" value="Xaa-pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="8">
        <location>
            <begin position="12"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="7">
        <location>
            <begin position="315"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="9">
        <location>
            <begin position="541"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN00352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="606" mass="68457" checksum="BB0A74A0BC905550" modified="2016-11-30" version="1">MISPVNTTLQLLRLRTLITNLSIAAYIIPLHDTHQGERTPACNARLRYISGFTGSSGSALVTRTEALLWTDGRYFIQARQEMDNNWNLMKDGIPGAISMETYMEKALDSRVHVGVDPTLFSKSAWDNMQSNLRNGQRLHPVQDNLVDEVWGEERLQCPEGKLLQIPIQFTGKTTQEKLGEIRLKMNEQNAQLLVINQLDDIAWLLNLRGSDIYAAAVFLSFVIVKSDGFELFIDQSKLDSDIRSSITQDGGTINDYEEVNSRLTTLVSNTSGKIWLAKTCSYNLARIVPENRQIVDLSPLVLLKAVKNPIEIQGFKNALTRDSAILARFYSWLENAVESGENVTELSASDHLLKLRKEHEYFLTISFETIAGSDSSGASPHYSPTTRTNKQITQNSMFLIDAGAIYLDGTTDITRTFHFGTPSDLQREAYTRVLKGQIALATAIFPERTKGYMLDSFARMHLWNIGLDYGHGTGHGIGIDVHEGPTKITYSHSIAPDDRGFVENMMTSNEPGYYEEDSFGIRLENIVRIVKATGKNPTGKNFLAIEDMTFLPYQHKLIKKELLTVSEIEYLNQYQEKCRRIVGEYLKRHYPGDKAYDWIYKESPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5W1</accession>
    <name>A0A1D2N5W1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease P protein subunit p25-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000193">
        <property type="protein sequence ID" value="ODN00670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5W1"/>
    <dbReference type="STRING" id="48709.A0A1D2N5W1"/>
    <dbReference type="OrthoDB" id="424402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002775">
        <property type="entry name" value="DNA/RNA-bd_Alba-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01918">
        <property type="entry name" value="Alba"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Alba-like" evidence="2">
        <location>
            <begin position="44"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="21045" checksum="480210B6F7C7996E" modified="2016-11-30" version="1">MLIQGRNIAMDHYASEPLIEQCSDPFPFDIENDPSYFQIKIENKSASVRTLANRGLKNFGSGKKIVFIAQGRATTKAVSCVEIMKTYYKKPVHQITRISQIKARSYTDYEISSVINILISQEPLNADEEGYQVYNHRDPKKVLNMQQVEEHDEKQDAIDNSEQKENIPTTTPSDNINEDDEEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N677</accession>
    <name>A0A1D2N677_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vesicular acetylcholine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05924</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Vesicular transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N677"/>
    <dbReference type="STRING" id="48709.A0A1D2N677"/>
    <dbReference type="OMA" id="TRTPEVW"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030121">
        <property type="term" value="C:AP-1 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043195">
        <property type="term" value="C:terminal bouton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005277">
        <property type="term" value="F:acetylcholine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17383">
        <property type="entry name" value="MFS_SLC18A3_VAChT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000109">
        <property type="entry name" value="Putative vesicular acetylcholine transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00880">
        <property type="entry name" value="2_A_01_02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF13">
        <property type="entry name" value="VESICULAR ACETYLCHOLINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0532">Neurotransmitter transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="32"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="525"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="525"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN00757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="579" mass="63313" checksum="D1A5231EF6EE5E31" modified="2016-11-30" version="1">MPQVPILNLELAEVKDFILAKLEDEKAQRKMVLVIVSIALLLDNMLYMVIVPIIPDYLRRIGSWDTHIEGGTRVTEAPRTITFTNQTGNYTYREAPPPPKIINGVIVYEGEDSAIGMLFASKALIQLLINPFSGAIIDRIGYDKPMMIGLTIMFFSTAVFAVGSSYSLLFFARSLQGVGSAFADTAGLAMIADRYTEERERTKALGIALAFISFGCLVAPPFGGVLYELAGKEVPFLILSFVCLADGIMLWLVMKPIKKQQKEQNVQKPDGTPIWVLLMDPYIACCAGALVMANVSLAFLEPTISVWMMDTMHVSQWQQGMIWLPAFFPHVLGVVLTVKLSKDYPQYQYLLAAGGLALEGLCCLMIPFAKSYWLLMIPISGICFGIALIDTALLPTLGYLVDLRYVSVYGSIYAIADISYSFAYAFGPIIAGRVMENIGFTALNIGIAVSNLAYVPIIFFLRHVYDKQFQDEANVIMKDPPDKQYQTYAMQNRSAAPDYSKTYGRLEDDDDDIGGAGSHRVTFQETSLNSSANGPSNMPNPYSWGDEPGAGTEPAGGNQYSAGGAPGAGGSATNPFRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Y2</accession>
    <name>A0A1D2N6Y2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein lap4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05664</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000176">
        <property type="protein sequence ID" value="ODN01001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N6Y2"/>
    <dbReference type="OMA" id="SNIGRCE"/>
    <dbReference type="OrthoDB" id="2187496at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014069">
        <property type="term" value="C:postsynaptic density"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045197">
        <property type="term" value="P:establishment or maintenance of epithelial cell apical/basal polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098968">
        <property type="term" value="P:neurotransmitter receptor transport postsynaptic membrane to endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098887">
        <property type="term" value="P:neurotransmitter receptor transport, endosome to postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043113">
        <property type="term" value="P:receptor clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050614">
        <property type="entry name" value="Synaptic_Scaffolding_LAP-MAGUK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119">
        <property type="entry name" value="DISCS LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119:SF44">
        <property type="entry name" value="PROTEIN LAP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="724"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="973"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="1070"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="425"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="473"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="525"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="678"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="824"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1239"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1319"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1521"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1649"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1781"/>
            <end position="1862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1933"/>
            <end position="1979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="703"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="831"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1251"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1336"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1434"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1521"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1547"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1669"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1689"/>
            <end position="1711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1713"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1796"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1824"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1940"/>
            <end position="1958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1968"/>
            <end position="1979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN01001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1979" mass="216824" checksum="F8E62DC9E6C24286" modified="2016-11-30" version="1">MKKWTAKGMSCVPFRSCNQHVEYVDKRHQSLSSIPDETFRYARTLEELLLDANHIRELPKQLVNLTRLRKLCLSDNEIRELPPNLGNLGNLAELDVSRNEIQTIPTSIQSLTRMRILDLSSNPISVLPPSFCAMKSLTTLTLNDTALTELPEGFGNLTSLVSVELRENALRGLPPSFESLRNLERLDLGDNELTDLPPFIGKLTKLVELWLDHNLLFRLPKEIGNLEKLMCLDVSENQLDELPDEVGNLRSLTDFIASQNNLDRLPPTFGQLSNLTVLKFEQNKLSKIHPSFGMCTKIQELFLRENLLEEVGDWITSLANLKILNMDCNRISSVTEKIENLKSLGVLSLRMNLIERLPHEIGACGNLMVIDVSGNRLQNLPFTITSLSLLKAVWLSENQSQPMPHFSTDYVLSEPVLTCYLLPQLNSDSSQQNQPDDDRSAEARGERDKFGLPIMPPSDPSLVEIDMSARNTTVKFQDRSDDESSVNGTESESTGFVRHNTPHPRDLKAKFQKWFGGAKPKSKTVDKVFVAPDENENSKGPFRPERQKVDPDLYAGEEPHKSTSPPPQAGFREMEENRTDTSEAEETEEADTDENAHNMVMRTHDNISYNDNLSDDSKEEKHVGFDVDYRDESEEYQQEERVNLRLHRRDTPHHLKNKRINAEGGDADTLKAILQRVQQRSTHEPKENPNPVESQRPPENDVGDSTNSTTNKQPQVLPITKTLQLILNREVGHPFGLNIAGGLGSSPFMDNDQSIFISKVVPGGLAEAAGLEAADRVINVNGVDFTNIEHKAAVDAIRQAGSKIVFIVERKVSDEHPAPVVAAADNHQRESLQSPAASSSFHPNSGRISGTSSKENLTEVKALVTIPDPEQSSNVVPPHQPSPNLVFPCPKPYKGISSFDAMIPSEVKAPSAVVTVTIKQPDAVSERVSDIFLPAPTDLGTVTETITKSTLTETVFTRVTHNEPVMVPLETEIINIDKSSSESLGVKIVSGSDEDCYPFGNNQAGVFVVYLTKNSPAARCGLRIGHRIIEINGRLVDPTDKNKIAVALLEAGNNIELKIRKHPPPPGFLEVDLTRAEGEPLGMHIKGGTDNPGNPLRKNDSGIFISKILPNGAISRCGIMKVGMQILSVNGHPLLNVTHNDAVNVLRGAGSEIEMMVANGYDPNEVDRLRAEGKLPDKIVEVLSNSEEAAAAAAKVSAANHSPVPESKELVEAKGPVAKPSVDKVMEVVRAAEQLVVPSSPTGFKDKGTKSSSSTAVAPSSPGFDVRKTTVVMTGHSLTSPGLGGQRKFHDDDTVEYPETLEPKPRTHLSSHENATYANLNDLHHSSVGNSSEGGLGRERSESAHSDDMLRNGEREDVFIDSDGVNGGVEARNPVFNGNSNNLHNEIGLPPVPPGGYRQKMVPTQLPLGGSSIHSDSSNDGKEGPGHVPPVPTPRTSIGSIGGRSSPSPLEEGPKELRVKIKDLSPKTVNVQLTVPLAPSDEFEPEEQEPVFQFKPAFHRVPSPIFNTPFVTFIPPEAAESTFSNNRRTVTPQKSDDSSAEEVFNSVPPPPPEVPPPPKDTNGQTISDVRASTVSARAKFFEQEIQQLSTTSNKPATKQFSFLSQYEVDRMKQEEEQKIAAIGGSMDVLRTTELEQVVEEDEDFYLEELNNSGDMDGNDEKLRGGSHGDISTTSGLGDSSTRINASSRASGQTRSISASSISSISSTGSIRTAKAERRLNDKLSREGSLRGIDPTLGMDLSPSEQRALQAEKRAAWRKARLKSLEQDAVQAQMVLNRMNELIDGSPTGPNSNNQSAEEHGSTEKLDNDGNVAADEENNVSIKNTSKSSTFKSKSYSSSTFTSTNEPFFETKESSSSDSELPNVHFPSLYIRKKSAGPKKVVGERERVVGEKVSRKTQEWFNEATGNFEIRTVEIIEKIIEHEVETTEQKIISIELDSPLKSPSSVSGEEPTGSNQETPNSSGGNTNGGKRKKRKGSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N711</accession>
    <name>A0A1D2N711_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N711"/>
    <dbReference type="STRING" id="48709.A0A1D2N711"/>
    <dbReference type="OrthoDB" id="6337346at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF5">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905138" description="CUB domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="2">
        <location>
            <begin position="227"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="412" mass="46280" checksum="4F27387357852093" modified="2016-11-30" version="1">MVVSSYSVKLFAVILLIVCLFDCSNCHKNKEKETHPKKELHKTSREPRNGFFPFLWVTFPPSPCGSQNEGTCVQRGRCSRNYGGTVSGNCQDGFGECCIITEECNVNRTQIDVTPLVATLKSPTSTDTECSFRFRKETNICQIRLDFVDFKSEHADVEGNCATDRLRITGSITVEDFTTCGILDTQHMYLTYGSKDIIEVTPLFKASSSRYKIVATKIPCDSKNRVPDYCFQYYTKPTDMVRSFDFGEAGQQQNNQYYTVCVKPMSQSSSIQWKSCPATTNAFTIVSSFEPFDPPCTRDWVQIRGKDKICSTTGFPVTTSKWKPYELMVNFDERELPDLGSLVSQTLSINLTNNTCDATRCTIDVPIMGYDCSCQPPTDGQCTCISRENSPFPPPSSADFDNKGFCLEYSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N715</accession>
    <name>A0A1D2N715_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">28S ribosomal protein S28, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05638</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N715"/>
    <dbReference type="STRING" id="48709.A0A1D2N715"/>
    <dbReference type="OMA" id="RRVMDEN"/>
    <dbReference type="OrthoDB" id="6020229at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019375">
        <property type="entry name" value="Ribosomal_bS1m"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13447">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13447:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10246">
        <property type="entry name" value="MRP-S35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN01059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="179" mass="19388" checksum="AF13F5598ADBA489" modified="2016-11-30" version="1">MISSRVSGVGMPIMLRLSKEMVGLQRSLCSSVMFSRYAALSTEAESSSSPPVSTSPNEPSKGGFAKAMAKIEGHESFPKTLRYSPLIQMGDPQGKIVEGSIVHVVDDDLYIDFGAKFNCVCPRPQKNGSAYTLGKKVRLMVHDLELSTRFLGAKTDLTILEADCSLLGLARSEKDKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7H6</accession>
    <name>A0A1D2N7H6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_05456</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimers with GPN1 or GPN3. Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000166">
        <property type="protein sequence ID" value="ODN01220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7H6"/>
    <dbReference type="STRING" id="48709.A0A1D2N7H6"/>
    <dbReference type="OMA" id="ATHNYFL"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="283" mass="31555" checksum="83BDAB3F81895290" modified="2016-11-30" version="1">MSSYSATNTLSSEDQLVIYGQLVVGPPGSGKTTYCHKMGDYLKAKFGEANVKLVNLDPGNDVLPYTCDLDVCELITVEDVMDRLKLGPNGSLLYCMQFIDENFQEGVISKVSDLFKNCNKMEPCWLLFDMPGQLELYTHVPAIKSIISKLEKMDYRLCCLNFVDSHYCSDPGKYIACLLTCLTSMLHIALPYLNVLSKVDLAEKYGKLPFSLDYYTEVLDLEYLTDMLDADPLTARYKSLNSAVASIVENYGLVSFLALDVNNPNLLTKVAQAVDKCVGRFVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7S1</accession>
    <name>A0A1D2N7S1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Venom carboxylesterase-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05382</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000161">
        <property type="protein sequence ID" value="ODN01309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7S1"/>
    <dbReference type="STRING" id="48709.A0A1D2N7S1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="244"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1012"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1023"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN01309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1032" mass="115649" checksum="F7EBB76A0041E220" modified="2016-11-30" version="1">MRTFPLRVMWKQIAPYFLGYRDIGQSPENYPNLTRMVEEFYFPGKTPRQASLDDFGDMTSDRFLTFGIIRGLQAHANYYPSGTYFYYFSFTDGRHNLANFIGYKGSEWGAGHTEDIFFLFNNTYAYAGHDQKDPDTELAPLIAPKHASSRVPEYRTDEGKLIRIWEPVHNASDIQGMQFDKEVKMIPLPRRYPYPDTSVSEAVVFRDKINVDNDYDLEQNGVGWEDGKNDLYKDTDYNRSHPLVASTSTGKVQGYWMKVVGGRKIRAFEGIPYAEVPNAERRFKAPVPKTPWTGLLKATLKGPKCLQYNQISSLRVVGSENCLYLNIYTPRPQYNKTSTRKYPTVIYIHGGGFLTGSGNDFGPAYLLQRNQILVTINFRLGVLGFMSTMDAASPGNYGLKDQALSIKWVFDNIKAFGGDPGRITLLGHGSGGSSVHFQMVSFKARGKFQAGISISGTAFNQWAMHTRAQALNLTKAFAKSLHCPIHGRTEDTVSCLRRQRGFDLVKMQISFLDTWPLALSLFRPVMEDEYQKEDPFLTETAEEAYARGTVDKVPWICGQAEDEGYTFLLSHVALGTFSNLRQKWNTLAADFLNYNDLPVDQDEITRRVNWWYFRNVNPANAPLKVYSDALGARLIHTGIHKALQAHSQHAETYAFMFGFNGKYNLATAAGIKPKEWVAVGHGEILGYILNSTNMYSGFKNTDSELVLSKILVNIIYNFVDKQIPGFTTETGDDFHLWNPISDPRNMSFLLIDKDIKMIPEPYLKQILYWESLGLPDSLPLGNFSSEIHNASDPNQSGFVSTDITNTGISVPDDLRPPTELKAGNLGQYNYIPENVTTSTRSNIISEPTTIKPPASITTFPSTSITENSNSSESTTLIPITTTNSATTTATFTPLIIPSTPSTPKPPTTARWIAQTHGPIPQFDTPIFKDLETTTTNPVSTSTLRSMRPTMGNIFAGLFGPDRRRNNSSASQNLTRGISIPIISGNYDARFITKSNITQMYLNTLGIDLTARKDTDPHPDEMMITSSNSQLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8H2</accession>
    <name>A0A1D2N8H2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000155">
        <property type="protein sequence ID" value="ODN01385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8H2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905204" evidence="2">
        <location>
            <begin position="24"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="283" mass="30651" checksum="CD16C13A855142B3" modified="2016-11-30" version="1" fragment="single">MSRMRGLSLLALGICLVIPFGFARKWNTNKDSIVVDAAYSDDDEEGELHFDALDQPDRAECMTLDQEPGICVTLRRCHPILFSDNGELRNPSLAQDYSQSVDACVSQNAVDDEPVMFDEVDKPSTAAVGDRILCCAKDKIHYAHRSSLEASDEELAMYPTTTGFPVVPLGGEVNEDPTQPQVIEDLLVIDNGVSGPSAPAEPIIDVVESTEASATNAPQKLSEESVSEITTSLPIIGDVEPQPEQPQSPLPSPEEPQSEPLIPDEPEPQPEQPSITAEDLTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N905</accession>
    <name>A0A1D2N905_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000141">
        <property type="protein sequence ID" value="ODN01724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N905"/>
    <dbReference type="OMA" id="GPYISIN"/>
    <dbReference type="OrthoDB" id="10634994at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905237" evidence="2">
        <location>
            <begin position="28"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="615" mass="67205" checksum="642D3E11248B4CFC" modified="2016-11-30" version="1">MKCSVVYFGSLVICTFIACGLFQGGDAGKTLKLPGYRLKFGTWPLVEVSKTGSRFKHGRRAKNNGPPRNHQRPPNGYKLGPPPPGKLVLVNPGEHKGSLHQQLQASLKHYAKQPANQNLPIIVKSPGPNPPPPPPGYKLGPPQNSLNSNPLQFTDASSPSGSNYGPPPLKFTDGKPWTPGPPPTQGSSFNSQGGRPSKLYSALKHSSFSEIFNNGYTEYRSPEVLEGRPLPGPYISINPDGSQVTTYVNEGVMPGPGSGIEVQPSIPPLLKLGDNLPDNYRVIFAQRQILGVKAPDTLANSGNSKPGTQEYDVALNLGTKYEQGYGPKPAEHPPLLIQKFQKRGDHHQHHDYVPQELPDTGLMATTNIVFATPNISAPLGGRNSKLFKAALEEKQRVLKARRKEKPLDAQVKLLGRLFTKLQRLKPPKIAVPIDHYEHKPLDNDDEEEDAWKKVAKSKVDSPVMAVQIQTFSVPDVDSTDPDIVESMAEFGTHDVEFAETDEIINLMEGVMKHGSGRMKLRDLGSNPQEINENLSNWVRRHLTLTRDVNQEAHAKGEELANGQFKQYQTFVTPSGGGGNGWSSSGPVPVDPKRGSRSMPLAMTHMAASMTPVSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N938</accession>
    <name>A0A1D2N938_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LIM domain kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04933</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000140">
        <property type="protein sequence ID" value="ODN01747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N938"/>
    <dbReference type="STRING" id="48709.A0A1D2N938"/>
    <dbReference type="OMA" id="KCHIFIG"/>
    <dbReference type="OrthoDB" id="20134at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="111"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="32480" checksum="C4CA983C55E543E7" modified="2016-11-30" version="1">MANCRGTCHRCGETAVGLIMTAGAMKFHPECFLCCRCQSCIGDDEQYILVGLSTLYCGGCWKKEPFPLLEKQHIIKVVTIPPLNRDGTQYKLKTDWNDCVTYDECPTVPQVSEIGRHGPECQLSVGDRILEVNGAPVHDRPIPDIEKILNQRTSVVQVTVEQTPTPEMPARKLEESKSFGSLSSLELRSWDLWGSYSDVECYNKDRLTNKKRDEHRSRASRRSKGSRERAASLSRLSDSSPTPPNHSRPGLARTLSFREQARSQCTFRACDLVKGELLGKGFFGQVNIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9C3</accession>
    <name>A0A1D2N9C3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA dehydrogenase family member 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000137">
        <property type="protein sequence ID" value="ODN01844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9C3"/>
    <dbReference type="STRING" id="48709.A0A1D2N9C3"/>
    <dbReference type="OMA" id="YEREVKY"/>
    <dbReference type="OrthoDB" id="190089at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF56">
        <property type="entry name" value="CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="144"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="444" mass="50424" checksum="7505A9226AD401A8" modified="2016-11-30" version="1">MSVTQSSLAKLFSGVVSFLNEKYSENCYSIKSFSIDTPCSAEDNFLSEIFAIKLNVKRKEPLNCKDAGVETQELIGKAQIIDDTEDVRRYVFNLIFTKEMLIYTDIFQRMEKLYTQAGISSSSSLALAPKLHHYYTEGESYSCLFMDNLVSQGYYIPTTHGTGIQLDECSSVMRAIAKFHAMSLVIEGEDQIPLTEKYEICTAEFFLSEATASTMQPLVLGSYAGIIQLAEKYRPDLVPLLESYDQEESIFDRLCKLVKPGTSSFSCLCHGDARLNNIFIKRDDISNVRFIDFQLTRYASPLTDLQYILNVGATKEFRAQYTEQMLRTYFEEFTLVLNSFPSLNLLPTQEAAVRGWTMEKVKEEYEGMAPYGFLVSLVLLPIILLLPGDIDKSVGQMSKAERETFWNAGRKQMVFELGCKHPDVRERLFDICDEAFAVINKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9V6</accession>
    <name>A0A1D2N9V6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BTB/POZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000139">
        <property type="protein sequence ID" value="ODN01766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9V6"/>
    <dbReference type="STRING" id="48709.A0A1D2N9V6"/>
    <dbReference type="OMA" id="WARHECE"/>
    <dbReference type="OrthoDB" id="636773at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022008">
        <property type="term" value="P:neurogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774:SF3">
        <property type="entry name" value="BTB (POZ) DOMAIN-CONTAINING 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="eEF-1beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN01766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="407" mass="46319" checksum="56D6A6D53F908508" modified="2016-11-30" version="1">MSSNWRDQAPTGREQFHYVFQNNLFSDVRFLVGSEQTPVYSHSFVLKVRSAVFEKILEKLHGPIQEIVINGVTISGFNRFIQFLYTDQLEASAEEALEILPLAKKYRVSALSKQCVTLLAEGIRESNAASIYNVARDLKEIELEQKALQFIQNNASQVFAGKDFLHLNNDNLSQLLKMDELDITEINLFNALMEWANVECGRHTLRATPKHMRMVIKDALYLIRFPIMSLSEFNADVVSKEILNEKEIKEVTKYLETDLTDREFVKPTLFSSMARNLLHEDQIDLSKTDDDAHKRLAKLAILKSNPSPSSVPLIVTSLILEIEPKSDVIDLEELKTEIGKIKKYGLFWGASNAVELPNGKQKFRISFAADTRRSYGVGTVVEAVLDLENYVSQVFVHSFKDEIVVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA60</accession>
    <name>A0A1D2NA60_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Helicase domino</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_04525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000123">
        <property type="protein sequence ID" value="ODN02140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA60"/>
    <dbReference type="STRING" id="48709.A0A1D2NA60"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000529">
        <property type="entry name" value="helicase SRCAP isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="79"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN02140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="388" mass="44696" checksum="C5988BDDEA3FE237" modified="2016-11-30" version="1">MDVLTRYVMYIPAVSAPSLEGRFYRPPCSSMYLEHVQQLENYRKNFTKPTEIVHPVMSRMLTQFPDPRLIQYDCGKLQTLDTLLRKLKTGSHRVLIFTQMAKVLDILESFLNCHGHTYLRLDGATKIDQRQLLMERFNADTKIFCFILSTRSGGVGVNLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSEKTVEENILKKSNQKRLLGELAIEDGKFTTAYFKQNTIRDLFTINEKDDVAKRLSTWNTDEQSTPLSTVEEEDESTTFDSSDLMKSLAKKHEIQTIECALAVAEDDTDVHAAQTVHAEAEAEMAEFDENVSLDALDDQWKAGPNKFEIEFQQIFERMTDVERYAMRLMELTIGDWLIEAINSSQKDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAC5</accession>
    <name>A0A1D2NAC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAC5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="289" mass="31228" checksum="89005D8FFB2C6048" modified="2016-11-30" version="1">MVMTVLTHLEVERLNTKYYNSSSSSDIFPVTSRRDRKRGGGSSVISSSKSSVGYLRPTVHPQVVCDIPVKRLPYVVNFSRLSSSNMDLLTEQDRPRSGLGGNASVLSDNYRKDWAHHNSRGNGPARASSVISLHSAPPLSNSENFRHSSVDLTAGSVLQTPPHSPRQSTYSTSPSASPVSHSRPLSSPEERFQGNNSNNDTPTPKSRAPGVPQELWDGGDCVTGNKTVVMLNSPQAVISSSPTLYQPAPYNRQKNFRPVDFQPSSGGLSSPAHAFHHASAKLTTPTPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAI8</accession>
    <name>A0A1D2NAI8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-aminoethanethiol dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04424</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000118">
        <property type="protein sequence ID" value="ODN02274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAI8"/>
    <dbReference type="STRING" id="48709.A0A1D2NAI8"/>
    <dbReference type="OMA" id="VRDCEMS"/>
    <dbReference type="OrthoDB" id="271433at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20289">
        <property type="entry name" value="cupin_ADO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012864">
        <property type="entry name" value="PCO/ADO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22966">
        <property type="entry name" value="2-AMINOETHANETHIOL DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22966:SF61">
        <property type="entry name" value="2-AMINOETHANETHIOL DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07847">
        <property type="entry name" value="PCO_ADO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26504" checksum="524767A88DC250F1" modified="2016-11-30" version="1">MSNSVIKNLLTKAFQAFKLRPLEGETSEASQSAFISELTHLQEAVRAVTGEDLSLEETVKSIPKSNQQPVTFVDIFENSMMTMMVIIMKPGSRIPLHDHPNMYGMIKVLAGQIRVQSYTLLDEPGKIMDHHTPKNTVLSALRMPETVLSKVSSPVTLAPEIRNVHEIECICGESADKNYAAFLDILSPPYPDADSCHYFRAEDHSQRTDGSGELRKCRLVQIECPKDYFTACSSVGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAY0</accession>
    <name>A0A1D2NAY0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000120">
        <property type="protein sequence ID" value="ODN02225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAY0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="19065" checksum="B29F22D5F18BA060" modified="2016-11-30" version="1">MDSNDANLSDSVDFSAGKSALLQALALMNDNGEVASKISNVLDSVQEDRSRTVQLFCEVLALQKDEVERKKKCVDLLEEVGKWWKLLVDDREKLLVTISNLEMEKERILKRQSHPQEIYGKLVDAASKTQLLNRSMNSQLNFSRMNVVDANAEDDFVEATTTTINSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBE1</accession>
    <name>A0A1D2NBE1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">26S proteasome non-ATPase regulatory subunit 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBE1"/>
    <dbReference type="STRING" id="48709.A0A1D2NBE1"/>
    <dbReference type="OMA" id="ESKIYHA"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000007">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="210"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="408" mass="46116" checksum="68CB23235261786B" modified="2016-11-30" version="1">MASAQVAKATPFRSGAETTPQPMESDDNPFETEEGIMRIAQECKDKKDSKRFDELIQRVRTFVNNVSKAKAAKLVRSLVDMYLDIDATSEQQVKVCQDCIDWAREEKRTFLRQSLEARLVGVYYDSENYTAALNLCGLLLKELKKVDDKNLLVEVQLLESKTYHALGNLPRARAALTSARTTANSIYCPPLMQASLDLQSGILHAADEKDFKTAYSYFYEAFEGLDSIENPRALVALKYMLLSKIMLNLPEEVAQLLSGKLALKYVGEDVEAMRAVAQAAHKRSLKDFQQALEKYKAQLQEDEVVKAHFNTLYDKMMQQNLLRIIEPYSKVELKHISKTIDLSIPNVEQKLSQMILDKQLNGVLDQGEGMLVIFDTIQEDKAYDAALGLIQNMGKVVDALYHKAKRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBR2</accession>
    <name>A0A1D2NBR2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_03996</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ZNF277 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBR2"/>
    <dbReference type="STRING" id="48709.A0A1D2NBR2"/>
    <dbReference type="OMA" id="NEDENDW"/>
    <dbReference type="OrthoDB" id="278606at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040048">
        <property type="entry name" value="ZNF277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="515" mass="59786" checksum="3A0710BF8B507652" modified="2016-11-30" version="1">MSINDPILEVLSFSLENDLALVSPKPQQPSFSSPSQNTPLARLERAVTGPKDADSGFTESFTPSSVLLEEDQKTLCPISECEYFCDKNICRDANAQQEVLAHLLKEHQLVIENPKEIANLSKYLEYWRKKLRSAPLTEFCVGFTMNTVENPSETNSSKLEGSKVSGESAEAKTDRDRSAQGSDGALYYMLSPDLPEDLQLRKQLWKRRLDIVLDVNRQEREETTFCRRCLFCWEVVGENRSKYFLHMRESHNFHIGQPDNLVFVRELLKLIEDKLNRLECLFCEHIYKDKLVLKEHMRKKQHRKINPHNLEYDQFYVVNYLEPGKTWENIGLEDTEGENREEEWVELAEEKQRNVVCLFCSAADCNFDNILDHMKTEHHFDFLQITVSLDFYEKVKLVNYIRRTVYQMSCLSCDERFQERELLLKHVSEHNINGSAELMPTVEKWNQAEYFFPTYENDDFLTFLDDDKQNADGSSGSDVGSNVIPEDLPPMATTSRDFDLAGFAIRYHNESNASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBY3</accession>
    <name>A0A1D2NBY3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000108">
        <property type="protein sequence ID" value="ODN02506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBY3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="118" mass="12783" checksum="69C78CB6CFD394A8" modified="2016-11-30" version="1">MSSTRTGSVNKLEISPGFDASYNYNQGARSINSTISMGKPNSNGHKHTIHYVDEVEINQTNYKIGLFAFTVKGRSATNYEVKLDESGLDAGSLVVNSISPSEVELSGTKQGVKQKLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND72</accession>
    <name>A0A1D2ND72_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND72"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="470" mass="51400" checksum="49E6AE379810338C" modified="2016-11-30" version="1">MIRTGYSVDVSEKDLGNEDFFGDVFGAGATSSNAGATANTGSKRKLADAQTTAIMKLESLDLDSEDEDVLILDTEGDPLLALDGIDLIEPEVEQRKPKDVLVTRTLGRVVVNTRNNVPLSTSANNEGSKDKNKWLRSVVDNNGQLRCTVSNSVDNVSNSGDTESLMADTIKGLVNTYLTKRSLVVDEAGLVSTPLHVVKKLASEHGEQIHCEGTAFSNGYHRMELFSGNLRGIGEGMTMKIARQMAAIDLLEQAQLSGPGARVPPMALLPGWLTNPAVFRDLFTLCKKKDLPRIKIESKLNYDETSGVQPTLSKWRAVCTVGDLEAVGESEEDIFARREAAKEMYQKITNVEYKDQPIAIGRSCLRLGELGGTGFQPIMSNQKKVWLLKNRVVNNKLVVREDEDDLAVYDIDELNKDLSEADLLAWQPGIGKKLKVTVRNDDDDQLSVASSSISRCVSIDGMSNAGTDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDS5</accession>
    <name>A0A1D2NDS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Metaxin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03265</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000075">
        <property type="protein sequence ID" value="ODN03403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDS5"/>
    <dbReference type="STRING" id="48709.A0A1D2NDS5"/>
    <dbReference type="OMA" id="YFQTRCL"/>
    <dbReference type="OrthoDB" id="198787at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019564">
        <property type="entry name" value="Sam37/metaxin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF38">
        <property type="entry name" value="METAXIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10568">
        <property type="entry name" value="Tom37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal" evidence="8">
        <location>
            <begin position="45"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="9">
        <location>
            <begin position="189"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="29357" checksum="54F409B44509E3E4" modified="2016-11-30" version="1" fragment="single">MPTATALMPPDIDFDSKEPWAADSELIIPIESTQVLIYESAAILGAQAFLNIARLPYAVKERKNATEISPNHKLPVLRCGAYVVSELEGIVQLAQAKGVTLSEYLNASEKADLRAYMSLVHNVLGSALLFFTWNDNDVYNNYTKFRAGAAYNYPLKAIMPWHIKRKVLTQLKTLNWTERTSEEVYHEVETCLTALSERLGELDFFFGESPTELDALVFGYLFTMITTPLPNRQLGNLVKHSPNLVKFCQHVEKEYFSQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF88</accession>
    <name>A0A1D2NF88_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative Xaa-Pro aminopeptidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02754</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF88"/>
    <dbReference type="STRING" id="48709.A0A1D2NF88"/>
    <dbReference type="OMA" id="DSYFWYL"/>
    <dbReference type="OrthoDB" id="4215474at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF4">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="6">
        <location>
            <begin position="77"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN03923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="525" mass="59344" checksum="4C3AA9D39F93797F" modified="2016-11-30" version="1">MSSTSPRLLRYGRQLIKHRNIASVMPCGSFILPNNACSVTSWNTQQVRMRNMLSLGQPTLESHSEFFSDPEQVMPGIYKEELRSRRQSLCHIVSELVAKRGSEVNHLIVIPASSKKFMSENIPYPYRQNSNFLYLSGSYDHEAFLVLCVTGKEQLHTLFLSDPDPTSDLWDGPKTSPQAAVDHYGFDQAYLASEFESFMTSFAQKTKRKVKVWCEDRSIVERYLDPSFGFEFKNAESPKAIIDTLRLIKSPAEIDLMRHSSRIASEAFQQTIRFCAEWNAKGQTINEHQIWAKLDYECRMHGAERLAYPPVVASGGRANIIHYVFNSNKCQPNDMILVDAGCEFFGYCSDITRTWPVGGKFTNEHHKSLYEMMHKTQTELIKKVEPGISLDQLFGVMSEYLVKGLEELGIIKEGSSQSGNCQEIALRFCPHHVSHYLGMDVHDTATVGRNEPLAAGMVITVEPGIYLRTSSNQRDYLTKVGKEFNGIAIRIEDDVLVTENGHNVLTSSCPKSVKDIENWGTVPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHI0</accession>
    <name>A0A1D2NHI0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHI0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="74" mass="8410" checksum="8108045A6A596CE0" modified="2016-11-30" version="1" fragment="single">FVFLAYVCVIVYSSHQYRCNWQAGFTNSLPTPLIWLTCDAIKCVLCILVLVQLLYSCFFCAVNTGSFLDSDLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHT5</accession>
    <name>A0A1D2NHT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger CCHC domain-containing protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000041">
        <property type="protein sequence ID" value="ODN04536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHT5"/>
    <dbReference type="STRING" id="48709.A0A1D2NHT5"/>
    <dbReference type="OMA" id="TEYEPIM"/>
    <dbReference type="OrthoDB" id="10020961at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042246">
        <property type="entry name" value="ZCCHC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46242:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46242">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="257"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="42156" checksum="1FD260E0E490270A" modified="2016-11-30" version="1">MTRYARAGKGTHQRVAKDPTNWDELKPPPPQRLRGSEEPEKSSRPARKERFNKGNGKNKFTKHPKPFSNSSEGLSKGDDASAEPVKTFNRNAKARNPNMRGFGEGKSVKILGQFWVPLDDAKRLKGLLHKLKEQGLPRKEILEILKNDRRKAEKASKRQRDKTCFQCRQFGHVLSDCPNLKQAIAMPGSDGIEEAAMIADQGLLCFKCGSMEHTSRKCRRQGENFEFAKCFICSGSGHIARQCPQNSNGIYPSGGSCGECGSSTHLKKDCPDIVGLEGAPAKEDDSDAVTLRMSDPFSSTEYEPIMDDKVDDESVIPQSNTPIMDSQTTFQRKPQPNRPNKKGKRKAGDDNAVTDFGFGNNFEPTSAKPVAPKKKKVVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHX5</accession>
    <name>A0A1D2NHX5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine proteinase stubble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01852</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHX5"/>
    <dbReference type="STRING" id="48709.A0A1D2NHX5"/>
    <dbReference type="OMA" id="ETIAYHR"/>
    <dbReference type="OrthoDB" id="6261922at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000054">
        <property type="entry name" value="Complement C1r subcomponent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF129">
        <property type="entry name" value="LP15124P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="247"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="538" mass="59027" checksum="96BB9A913142F456" modified="2016-11-30" version="1" fragment="single">MLSAYWLLINLWISPDKVKTMKLHLGMLLVLCMATLPLVTSVTVSHDDDPNVPDETDMDIIGKYTESRTELDKSNETQNQPSSSSESPKDSEESTTTTTTTTAAPEKIQHLKDGVPCKCVKYYLCNVEVGSNTTSENGTLQGVADEGAGEGSVILGVVDIRKTELKNKAKESNATDSETTPSEDSPIECPHYFDVCCPIKNIKEEKPNTDAGETTTEKPHPPPPKDTSQYEHTTCGHRNENGAGFKITGATESEAQFGEFPWTAAIIELETTEDNVTINKYIGGGSLLHPQVVLTVAHGVLGKPRSALRVRLGEWDTQTNDEPFPSQDRGVSKVIIHEQFLKKTLFNDIALLILDEEEVRLAPNVETIAYHRQVCFSSGWAKIILVDFPLIIIIMVKYVSTYEIMLISLSLALSGVAGRYSEIMKRVSVPVVSKDQCQKDLEKSDRLPGFRLHKSFMCAGGGDSGDDTCKGDGGSPLVCSVGGKDHKHYVQVGAVSWGLGCKNSSFPGVYTDIMYLTPWIVKQMDREGMSSDYFSIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI89</accession>
    <name>A0A1D2NI89_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein Musashi Rbp6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000033">
        <property type="protein sequence ID" value="ODN04922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI89"/>
    <dbReference type="STRING" id="48709.A0A1D2NI89"/>
    <dbReference type="OMA" id="DFEFREY"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000025">
        <property type="entry name" value="RNA-binding protein Musashi homolog 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF4">
        <property type="entry name" value="FI20028P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="51"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="138"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="209" mass="22799" checksum="7A7D80CEB5AD23B3" modified="2016-11-30" version="1">MEGATINGLTQVTLENGLSAIHGPGDDNSARSSPSVGNTTASNGSVSGYENKLFVGGLSWQTTPEKLRDYFSQFGAVTDVLVMKDPITQRSRGFGFITFNDPGTVPRVLGVPVHMLDGKRIDPKHATPRSKSGSNKTKKVFVGGVSQETSVEEVKAYFSQFGKVEEAVMLMDQQTKRHRGFGFVTFESEDVVDRICEIHFHTIKGKKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIT0</accession>
    <name>A0A1D2NIT0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminopeptidase YwaD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01539</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIT0"/>
    <dbReference type="STRING" id="48709.A0A1D2NIT0"/>
    <dbReference type="OMA" id="YIMDMLL"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905636" evidence="4">
        <location>
            <begin position="22"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="5">
        <location>
            <begin position="216"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN05151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="544" mass="61185" checksum="F6D085A4F77AE937" modified="2016-11-30" version="1">MHKSLFTCALWSAVVAGAVLGILTEPEETEVFDSNPDILREQLVTWSNEFFSTGNYRGRLSKLEELTSDSSSNPSSSNPYYSYSHESSSGVRGGSDSSGRYNTFRGRLHSAASAPASTKLFEGADNSRINTRYHDVSRSDVDGKPVIKGENLEWMLQNIFMYPRNHATNESAKEIARKYIVDSLQVTSGLHTTAQHFQPLQFLSMYEGQSVPMGTNIIGIIKGSEWGTPNDLITVVGAHWDTVNFTPGTDDNGSGVAAMLEAARAIAHSNCRPKYSIIFVAFDLEEVGSQGSLVFIKDYLMEILKSNFPNELGVSRFQGAFIMDTIMNFNDTDGSQIFPTEWSLALPEVYDQIADNQHRGDFLSMIYRRDVDKKMAARFQYHWDKSTVEPRFRLTPFPLRLTAELPPMEVLADHLNFLRSDHSRFWYMNDSSVPTTLNAVLMTDTGPYRGNMKRCYHSVCDGPEVSLYSNPRSLKFLTKITQVLTDTLGDMSECQYTGNSNPNSQRSNFIKTNRVHARSSAFKHGSPLRNLFNFVRWMHNTGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK12</accession>
    <name>A0A1D2NK12_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_01067</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000020">
        <property type="protein sequence ID" value="ODN05618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK12"/>
    <dbReference type="STRING" id="48709.A0A1D2NK12"/>
    <dbReference type="OMA" id="YLAPPFG"/>
    <dbReference type="OrthoDB" id="1689333at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042283">
        <property type="term" value="F:dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF2">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="508"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN05618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="556" mass="63323" checksum="BADEE4AEB6446383" modified="2016-11-30" version="1">MTASSNFSVASYWTAVFAVSCLKLVLLHSYRSTDFEVHRNWLAITHSLPLDKWYYEETSEWTLDYPPFFAYFEWGLSQVAKYFDEGMLKVQNLNHATFETILFQKLSVIVVDFLLAYAVLKCFEASSVLFLTSDKQKSKSESGIPLETLFVLIFCNGGLFLVDQIHFQYNGFLFGIMLLSIAKMLEGKFYLSAFIFASLINFKHIFLYVAPAFGVYLLRRKCFPPNTPLRIGSVISSVFSFAVIGVTVLAASFGPFYQHIPQILKRLFPFQRGLSHAYWAPNVWAGYNTVDWFLNVALKKGKSSVTTGLVGEASLSVLPQVLPLHTFILTVVCMMPALIAIWKRPTPLNFVQGVIATGWTSFMFGYHVHEKAILNVLIPFALLSSHQPNLFFITLVSGTVSLFPLLFTPVEVVLKVLIAILHFSLVCRFIPLSKFRIYELFYLSGFAMVYLCENLGPILLPRFPFLPLILVSDYCLIGIFYSYVKFYWNFWRSIPNNLNVTKSKYDSVPPTPKTPMQFASDSPDSKTRNSPIKPIKRKRQSNVPEPSTRVLRARNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK39</accession>
    <name>A0A1D2NK39_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fork head domain-containing protein FD4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in development during embryogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK39"/>
    <dbReference type="OMA" id="HFPYYRK"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000082">
        <property type="entry name" value="forkhead box protein B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF377">
        <property type="entry name" value="FORK HEAD DOMAIN-CONTAINING PROTEIN FD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="13"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="7">
        <location>
            <begin position="13"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="129"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="256"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="343"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="655"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="416"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="524"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="584"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="758" mass="80548" checksum="C9E7EEAFCE60C8C6" modified="2016-11-30" version="1">MPRPSRESYGDQKPPYSYISLTAMAIWSSGEKMLPLCDIYKFIMDHFPYYRKNTQRWQNSLRHNLSFNDCFVKVPRRPDRPGKGAYWTLHPNALSMFENGSFLRRRKRFKLPKCDKELLERTLGSFSSHSSSAAGGMHHSQPSPSAASSPSSLGPNGMSGHGGLVPSMNMSPPIPGMMGMSGNHMMSPQFSHHLNSPAAAAAAAAAAAAVNGLHGVQFGGLPPYGSHGAPHPMFLGGGSAADARILAAAAAGYSPPRDLFHPHHHHHHHSHPNGLSPQQAGNLNHHLNSHHPSTNSHIHPGGAGGLHPAYHHHHPAGQLAMTPKDIEDLKEATLAIKSLREQSAKLKRAGGPGGISQPVPKRPYHLEHDESKHHNNNNIDDDKDRLVSPPESPPLTKVKRRGGSNNSNNFSIENLIAKDKQQNSCKETDNNKRNNNSGGKPNGKLDFQLDDEEMCDMMDGDDNNRGGRDSVLSDSVSISVSDVGSERLAPTDDLLDDDDHYEESIMNRKQKASANDTESIHSGVSSLRSARSRSNSPSSSSAAVNSSSALLRPESRDSVSSAGSRNNGKSGHVSHSPNSKPKHSLTTTSSSSSTSMIPPTSMVSCAPNIGSGMNTFAASVSAASLLPAAYPFYAAAFLSAQSLLQSHQAQYNLENSSNNSPLLNGRGHNSSPPVSSPSASGISSPNNHLPFTTNNLTHLNNLINNSTSGIGGGLVSSGNNNCGSAVASVIPTTAAAAAAAMLLTTERYSSAKDLSGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKG9</accession>
    <name>A0A1D2NKG9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Yae1 domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKG9"/>
    <dbReference type="OrthoDB" id="20086at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="150" mass="17245" checksum="70E42CB838A11558" modified="2016-11-30" version="1">MIQCNMESGDEDDAFTMGEREWQKMNRDLSKQGYRDGKTEGREKGMQESFGKAITLALNHSLQLGQLHGFLEWKFSHTEGKGQKDRIKLLMTRMGSHLEDLEDWSAESKSGDLKTEMEEKLKELANEYLQLYPKESAEVSSILGQNLERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLF2</accession>
    <name>A0A1D2NLF2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat flightless-interacting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00599</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LRRFIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLF2"/>
    <dbReference type="STRING" id="48709.A0A1D2NLF2"/>
    <dbReference type="OMA" id="RDKCREH"/>
    <dbReference type="OrthoDB" id="10028421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019139">
        <property type="entry name" value="LRRFIP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19212:SF0">
        <property type="entry name" value="LD07988P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19212">
        <property type="entry name" value="LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09738">
        <property type="entry name" value="LRRFIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="112"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="310"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="401" mass="45370" checksum="6229EEDA3C9DD3C0" modified="2016-11-30" version="1">MARLAARRQARAEAREIRMKELEKQQKEIDDNADRHYDMYSTGTGGGGGGGGGGGGSGGGDVVNRAAFRVALGSHRAPSHSVSSASYHSSRRSSEDSSEDGMVSIRDMRHELKELEDKFRKSMVHNAQLDNEKSALTYQVELLKDKIEDLEESLTLLQREYRDKCRDFENLKRLSTQIKDELEYCKAQLLEKEELIKEYGLVVVENEVEVDIGNGEKETRIKRSLVTQETAQVLSSLGSGSLDVRLKRFLEDKNDLLDQIRRLTIELEEERNKHSKGDRGGTQHSASNSSAYTNGPDESLDAHKDASKQLADYRFKTQKYEQEIATLQANVARLDGQVLRFKTAAEEAEAREDDLKIEKRKLQRELREAQSKLDELETTNSHLQKRLDKLKTAKSTLLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLW3</accession>
    <name>A0A1D2NLW3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLW3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905737" evidence="2">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="79" mass="8002" checksum="EAF93129C1F1DA62" modified="2016-11-30" version="1">MAKLFSTMLLAMIVIIGLTATTSAEEDKPSNKWFFFRPGPWIPLNIPLPQPAATTAGAAATTAAGGATTGAAATTPAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLW7</accession>
    <name>A0A1D2NLW7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLW7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905722" description="Protein quiver" evidence="2">
        <location>
            <begin position="25"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20515" checksum="46681F0BC6C52D51" modified="2016-11-30" version="1">MSNSIYILLIVCTLLILVTNGVDGIECYSCYHLEGGQFSESDLEKFPIGGFKGHKSCKSGKTPDDTYTTTCNADEDNTVATCVKLFYNGKLVNSSEVEYKLTFRTCFVAYENENFTQTCAESTIFDIGNYAAPSSPIKDLISEYGSLIGDRTGTFCSCDSDKCNTGASCMSSLFTIVMLGFTLLTFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMV1</accession>
    <name>A0A1D2NMV1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Enkurin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_00391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000008">
        <property type="protein sequence ID" value="ODN06266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMV1"/>
    <dbReference type="STRING" id="48709.A0A1D2NMV1"/>
    <dbReference type="OrthoDB" id="2123594at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027012">
        <property type="entry name" value="Enkurin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052102">
        <property type="entry name" value="Enkurin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490:SF0">
        <property type="entry name" value="ENKURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490">
        <property type="entry name" value="ENKURIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13864">
        <property type="entry name" value="Enkurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51665">
        <property type="entry name" value="ENKURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enkurin" evidence="7">
        <location>
            <begin position="221"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN06266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="37349" checksum="87E70FF36574A66D" modified="2016-11-30" version="1">MFTFLNRPQNTECVYNLIEQTVDERSRGPPIYRSKYSCMVRNQAYCNKTGCYKTMGVPKACLCPPQNYLKKNSRAPITIKPPAVPRIKLCNPPPCPDPCESQEGNNDCGQETQEESCEQQQPPCGPVCCVPKCRVPRICCNIMKPCVPNRCVGFEIIPRGCKNYIHSNVVKALRMPAKKPALRFVDHPKGHTQTWCDSGYPRKYVYKDEFGCVPAYVENIKEELRQDDLQAKYDMKFKERDIQQQIRPLDPTEHQALICGLKKNWEEKFAEYQSFSLLLDNVGKVKRKQAVEDELKRLEKDIQLLERHDHIFVSETCRSFYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMV2</accession>
    <name>A0A1D2NMV2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-centractin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the actin family. ARP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMV2"/>
    <dbReference type="STRING" id="48709.A0A1D2NMV2"/>
    <dbReference type="OMA" id="YTTWTGG"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000188">
        <property type="entry name" value="Actin like 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000502">
        <property type="entry name" value="Actin-Related Proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000008">
        <property type="entry name" value="alpha-centractin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN06594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="372" mass="42118" checksum="9C9A391FD9759A82" modified="2016-11-30" version="1">MELVNQPVVIDNGSGVIKAGFAGDQIPKCRFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLAIKYPMEHGIVTDWNDMERIWQYIYSKDQLQSFSEEHPVLLTEAPLNPRRNREKSAEIFFETLNVPALFVSMQAVLSLYATGRTTGVVLDAGDGVSHAVPIYEGFALPHSIMRIDVAGRDVTRYLRLLLRKEGHLFRTSSEFEIVKTIKEKECFLSSNPYKEESSDAEKRVYKLPDGNSLDIGPARFRAPEVLFRPDLLGEECEGMHEVLLFSIQKSDLDLRKILFQNIVLSGGSTLFKGFGDRLLGELRKLAPKDVKIKIAAPQERLYSTWIGGSILASLDTFKKMWVSKREYEEEGQRAVHRKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0C6</accession>
    <name>A0A1D2M0C6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zinc finger BED domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01009299">
        <property type="protein sequence ID" value="ODM59385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0C6"/>
    <dbReference type="STRING" id="48709.A0A1D2M0C6"/>
    <dbReference type="OMA" id="IEVLWIN"/>
    <dbReference type="OrthoDB" id="7239843at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140996">
        <property type="entry name" value="Hermes dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM59385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="25078" checksum="744B60786732ECB9" modified="2016-11-30" version="1" fragment="single">GKYFEVTKKDKDGHVEAKCVECFKTGRVQKYQGSLHVISNFTTHLKRKHPAALQSYTEYMKTAEAKAKRVKQTCLPFPVINTTSHLQSKTERLILNFVVQTMQPLSIVDDEAFKKLSTSNHLEIQLLNSLFPTFSTPGLNSEAKVMCRQTLTKMVSTEYQSRFSALKKTLAEVDWMCATADIWAPDIEVLWINYSLVDRRSQEKVGYFSLAKIPRCPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Z8</accession>
    <name>A0A1D2M1Z8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Larval cuticle protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006510">
        <property type="protein sequence ID" value="ODM86995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Z8"/>
    <dbReference type="OrthoDB" id="6379191at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF192">
        <property type="entry name" value="GEO02312P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17145" checksum="5DF7D7B76FE4836B" modified="2016-11-30" version="1">MGHLAVLGLESFCTFHVGIFLFFTCGCNTFAFPTPENATTITVLRDERKLDSSGSGKYSYSVELSDGTKLEQQGEKASDGGNSLVVSGRYAFVDPTTGVTHEVEYTADKTGYHPHVISPQDRENNMLSKNAASNRTDENEKPLETISASLFSSQSASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2Q5</accession>
    <name>A0A1D2M2Q5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative AC transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005773">
        <property type="protein sequence ID" value="ODM87253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2Q5"/>
    <dbReference type="STRING" id="48709.A0A1D2M2Q5"/>
    <dbReference type="OMA" id="ASGCFMK"/>
    <dbReference type="OrthoDB" id="8912104at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47501:SF5">
        <property type="entry name" value="HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47501">
        <property type="entry name" value="TRANSPOSASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="507" mass="58369" checksum="0AB29A9C36BBF446" modified="2016-11-30" version="1" fragment="single">NTRKSTRSTRRLNSSASPPTRKTLTGWAKNDFDRKKRNSKPFWNVLWVCATADIWSARRKSFLGVTCHWIDQNYKRHSVLLSMKRFPGKHTADRIAELFFRPTNWITKLRLSFTDNGSNFVKAFRDCQKELHLDLELDDLEEELFCENEELDENAIEAQDTFARLEEQSYASLPPHYRCVSHTLSLVATKDLDKELDLLKDKSASTCKKVMRSALAKCSAFWNKNGRSTQTAEAVTAILGRSVIRPVVTRWNSTFDAVQLLLEKLEHIDAAFDAAQIKKSLTAQEKEFLKEYNMALQPIAWSLDKLQGENCMFFGFTAPVLLKCDQKLNDLINTDSPFAKFMAMALKKGLSKRFEKILSLNIETARSEILSAICMPCFKLHWVPNDKKDELKRYFVAEANFWKKEVLGNSESEKSQDLKPADDFLEDLLDFDISDGQNTKIDLETQCLQYLQSNDRSLESLNIYPIVREMFFKFNTALPSSAPAERVFSYGGMLFTKTDTNESRKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2Y1</accession>
    <name>A0A1D2M2Y1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005559">
        <property type="protein sequence ID" value="ODM87325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2Y1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="124" mass="13669" checksum="8EEB83A7EA6C181D" modified="2016-11-30" version="1">MGFHFCLTMSYPTQPNYPAQPSPFQQPGVYSPAVPQTGGFGPTQYAAAPAEFAPGFTPNRAANPNRNYIIIAVVAGICCCLIIVILLVIFLLVPFFIFKSEKDKLDDLHQQHRSREQSAVLHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4J2</accession>
    <name>A0A1D2M4J2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Neuropeptide Y receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_18789</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004453">
        <property type="protein sequence ID" value="ODM87893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4J2"/>
    <dbReference type="STRING" id="48709.A0A1D2M4J2"/>
    <dbReference type="OMA" id="WMPLHIY"/>
    <dbReference type="OrthoDB" id="9445642at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF9">
        <property type="entry name" value="LEUCOKININ RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="69"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM87893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="360" mass="40703" checksum="4F179C42A830B4D0" modified="2016-11-30" version="1" fragment="single">MMTNESDYRVDVGFDRLNLSEDVFYEKDSNVTMEKNNTLSSDELYNVPTSIIVLLSILYGGISVVALIGNMLVLWVVTVSARMRTVTNMFIANLALADIIIGLFAIPFQFQAAILQRWNLPNFMCAFCPFVPVLSVNVSVSTLSSIAVDRYWAVMHPLKPRASKRNATYAILTIWFLGVFLALPTEIDYKVIYIPGKAGHNSKPFCTNLGLSPTFRMYYNLSLVVIQYFLPLIIISGAYAQMGRKLWGTTAPGNKEKARDTLVLKNKRKVIKMLALVVILFGVCWLPLQAYSILQTIFTSINQYQYINIIWFSFHWLAMSNSCYNPFIYAIYNSLAKKFMRRQVSDRVPSSTQIPSGCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4U1</accession>
    <name>A0A1D2M4U1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Venom metalloproteinase antarease-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18684</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004273">
        <property type="protein sequence ID" value="ODM87998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4U1"/>
    <dbReference type="STRING" id="48709.A0A1D2M4U1"/>
    <dbReference type="OrthoDB" id="6497651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903474" evidence="3">
        <location>
            <begin position="23"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="4">
        <location>
            <begin position="136"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="444" mass="48715" checksum="EBDB35A07A913705" modified="2016-11-30" version="1">MSKSVTLVGFLLALAWPNPEKSFPNMGSKVAHQSTSRLTLKQGQYKLKLSKPDKSVLHPNIKVITVGTDAETGHDTYDYWTPSKNELNAAEDVYVDEKNLAAVRVNYDNGDRSMIGVVNGKSPIKQSSPNAAANDAVAEILVVCDKEFGDVFQHDRVKILDYLTVYFWDVNLRYKTLPSINLTFRVTGVVVISTPSGQPFIEEARAPDGRAEFGRILNRFSYWVYQQMSVVPKFDMAVAITNTALEWGGGLASANAACWVDNTQKRHVGTLVFNDGGDWGSLTVGTHEMAHTLGAPHDDDPNFPGGCTERGYIMGGGNDDLRWFFPLAVTADIADCKVMKCRLPGDSRIFSFPPVDNSPCGGQSRCFRGRCRMPGSLIRNVGDGRCLKATDPFAFTAPLEPVNCPRPGTPLDRFVISDDGIGKTLATPWETRDAKETGDKCIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4X5</accession>
    <name>A0A1D2M4X5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004231">
        <property type="protein sequence ID" value="ODM88025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4X5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="146" mass="15962" checksum="C32F6222FDABEAD2" modified="2016-11-30" version="1">MLPNPCPCTTLQWGVKVVAIVGPVFDLLNIFKITAILGGVDASDNFLLRGLQETSHPILIVSLILNMILLGVDIVLYLGAQKRNATMCWVWLGCTLVNFLYSVINSILKLYGDYGTTYVEILVVGVIGLIHGIAITIYVMFVVYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6F2</accession>
    <name>A0A1D2M6F2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003433">
        <property type="protein sequence ID" value="ODM88555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6F2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="146" mass="16113" checksum="160E86D95DFA2FC0" modified="2016-11-30" version="1">MLEMLWFLFKRGRPPKPTTKRGCKQVVLSSQGPQVQHQDATIPQQKFKCAKCPRRLTCSPVAIPHGKGSPSHVFTGLWVAPHVETYSTQNASILNIGNSFTLDFKGSHCQLPAAPGPEGPVRIRTTDSKLLTTLLCFPSAYQIMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M710</accession>
    <name>A0A1D2M710_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphatidylcholine:ceramide cholinephosphotransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_17911</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingomyelin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003209">
        <property type="protein sequence ID" value="ODM88770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M710"/>
    <dbReference type="STRING" id="48709.A0A1D2M710"/>
    <dbReference type="OMA" id="TTRIFWW"/>
    <dbReference type="OrthoDB" id="422827at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047493">
        <property type="term" value="F:ceramide cholinephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033188">
        <property type="term" value="F:sphingomyelin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006686">
        <property type="term" value="P:sphingomyelin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045221">
        <property type="entry name" value="Sphingomyelin_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025749">
        <property type="entry name" value="Sphingomyelin_synth-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290:SF27">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290">
        <property type="entry name" value="SPHINGOMYELIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14360">
        <property type="entry name" value="PAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingomyelin synthase-like" evidence="10">
        <location>
            <begin position="261"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM88770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="382" mass="42729" checksum="075EB7DDC64FB877" modified="2016-11-30" version="1">MVVASGKRDHRSLEPSSSEFGVVVGAVGTHCHSANSNPHQRPMSLTSGDLHFQQEPLLENCETAGWHSSSDHEVDVPLKASSKTRVNGKRTRSSEARIDMPPMSSFMTASFPKEKLKTVVAGALLVTAFMLTSVSIALTHQRLPDRTIYKPLPDIVLDNVPVQEWALSFSEILIMISLFVTITVGLLHKHRWIVFRRAFLILAILYLMRSVTMFVTVLPVSSYTYYCSPPANSSSALQTAQRALRLLSGFGLSINGEQVYCGDYIYSGHTVILVTAYLFIKEYSSHKFYLLHWTSFCGSLTGVIMVLISRGHYTIDVIAAYYITTTTFCIYHTLANNPSLKVKTGQSRINYFARIWCYPIFMYMEGNVGGPLPQKYSLPWSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M726</accession>
    <name>A0A1D2M726_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Sodium/calcium exchanger 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_17914</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003212">
        <property type="protein sequence ID" value="ODM88768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M726"/>
    <dbReference type="STRING" id="48709.A0A1D2M726"/>
    <dbReference type="OMA" id="CMVGLKD"/>
    <dbReference type="OrthoDB" id="418484at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098794">
        <property type="term" value="C:postsynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005432">
        <property type="term" value="F:calcium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051171">
        <property type="entry name" value="CaCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878:SF76">
        <property type="entry name" value="CALX-BETA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878">
        <property type="entry name" value="SODIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="610"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="640"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="13">
        <location>
            <begin position="352"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="13">
        <location>
            <begin position="449"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM88768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="657" mass="72592" checksum="27683C3452823273" modified="2016-11-30" version="1">MASSGEPLIDDSDKWNYNGTYNDICPRGLLLPIFPFEGTWNTTFRAILYCFGLLYCFMGVAIVADVFMGSIEKITSKTKKIYLSAGGKDSEPDVFEIKIWNDTVANLTLMALGSSAPEILLSCIEIIGNNFESGELGPGTIVGSAAFNLLVICAVCIMAIPNGETRCIRLFSVFLVTSIFSLFAYLWMLVILNLISPNVVETWEAALTFLFFPLLVLIAWWADRGWKCGKRTPTVADQQIELGMENGSPGGECESMLDKQKKLFTAEGDVDKEALIEFYKELRKFPHLNDTDAAILAATKQTANLIPDCGIVLVLYVIFPEAEKYIQYYPTNFVYDTINQSPDVPDIGDVPQITDQASQKSIVEFHAASYAVPVRIRVESFDGTAKAGSDYVQINEQIVFGPYAKERELTVKIIDDNQWEPDEEFFLRLSIIDDGYDRRDVVLGRLPIMEIIILNDDEPGVLSFRKRGLLVKESCQFACIDVERTNGADGDISVNYRTIDGSAKSPNDYQGSEGTLVFKHGETLRTIEIPIVDDLKPERDECFEIELANPEGGAKLGRITKMAITISNDDAITFVALGTSLPDLFASKAAATSEKYADNAVGNVTGSNSVNVFLGLGLPWLMAAIFMISREILSKLMPEILDLVLGSILLLHLLVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7I2</accession>
    <name>A0A1D2M7I2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003038">
        <property type="protein sequence ID" value="ODM88950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7I2"/>
    <dbReference type="STRING" id="48709.A0A1D2M7I2"/>
    <dbReference type="OMA" id="QNCEDIG"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="87"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="261" mass="30623" checksum="899BBB79E4C9C42D" modified="2016-11-30" version="1">METTPQSERDVLVELRRLITEFLYGGEGTPEVREYIASVYEDDSKLLIYLKGRKYRVNHAWETLKRKAEIICNDYPEYFPETLPKSAFQLINNHVYGALKARDKLGRRIICFNAGKWDPKEISVDELAGVVTHHLDLMLTDEDVLSNGIVYIQNCEDIGMKHVKEYSLHRMLRMLDIFCYAYPIQIKGIYYLNVPFYARYVYKIIRPFLPKKIKERLIISSNDQKFAALHDQLSPRILPKFLGGHLENEEAFDMTMLQHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8H2</accession>
    <name>A0A1D2M8H2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="8">HIU hydrolase</shortName>
            <shortName evidence="8">HIUHase</shortName>
            <ecNumber evidence="8">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17443</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01002783">
        <property type="protein sequence ID" value="ODM89239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8H2"/>
    <dbReference type="STRING" id="48709.A0A1D2M8H2"/>
    <dbReference type="OMA" id="CSENQNY"/>
    <dbReference type="OrthoDB" id="10265230at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00095">
        <property type="entry name" value="TR_THY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="116" mass="13107" checksum="2AE1F0280DE9FB16" modified="2016-11-30" version="1">MASNTNPLTSHVLDTAVGRPAVGVSITLSKYEGNGWREISKKLTNTDGRVGNLISSEEFTPSRFKLTFDTLAYYESRGEKTFYPYIDVVFEIERPEEHYHVPILLSAYGYSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8L2</accession>
    <name>A0A1D2M8L2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002728">
        <property type="protein sequence ID" value="ODM89310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8L2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="275" mass="30182" checksum="786A2B5EC187DA9A" modified="2016-11-30" version="1" fragment="single">LPPPPTKYSPSSSKFRAPPLVPNESLDFEISCTAFTQPPTQQLCKKQVCPPPACTTSFGCKSTVPPPPARFLGNKSPPQNQTVSPFALLKKITRFSPPPPQEITRFVGNKLYPPPTTTSAQLDFLGTSLAPSIKQVRPSSSSTESDLIEINCTRNNAPHVKEIIRSVGNNSPPPPLAKEIIGNKSPLNEEITRFVGNKSPPSPSQENTQTLVWPWVLVPIVLISFIIWMRDAGDAGGSFFEAAFFVQVPFLTATGTETRQFFEKNRRPEPGRQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8U6</accession>
    <name>A0A1D2M8U6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">E3 SUMO-protein ligase PIAS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_17282</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002674">
        <property type="protein sequence ID" value="ODM89395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8U6"/>
    <dbReference type="STRING" id="48709.A0A1D2M8U6"/>
    <dbReference type="OrthoDB" id="6586443at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16650">
        <property type="entry name" value="SP-RING_PIAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF94">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PINIT" evidence="11">
        <location>
            <begin position="141"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="10">
        <location>
            <begin position="332"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="71"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM89395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="495" mass="55054" checksum="445BDA07E08BD89B" modified="2016-11-30" version="1">MLEQEQMIKRMQLCDLKNLLKAANISFKPNQRKALLQKKCLESPSLRLLPDLVKEHYENYIRRRQALIIKRQRTSRGSETSSSESSFTENPEPELQQEEAPTLSKENALPATSTESAATSATFVNTNISAEVDSRSPSLHESVTQQGKVADKVEKESLQIQFRKSPFYEVQAVLLPPKVLVSSAAVQASPTELQSFYNFTLTPEQTEEYSRGETEIQLRFCKNDPFTVQDDRLPQNLEVTVNTKVIYKTPKFDDSFPLNELSKSPSAPLVITNVNTAGALRNCVHVLWGCNNTARSFVLAIFLVKKVTTEALVQQLERLTRHDTLKLIKAVGDDLNAAGPKTISVKLSVSCPIGMQRITLPIRSKTCSHVQCFDAKTFLAMWEIKPYSQARCPVCKDDLNFDDLRIDGYFAHVLTELSPRVGNVIEVTLEDGSWSACETVCSSSSTHSRKARASSTSRSAGGKSPVLIDLVLTPFSAANQNQHGSENPETVDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8W9</accession>
    <name>A0A1D2M8W9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Collagen alpha-1(X) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002708">
        <property type="protein sequence ID" value="ODM89344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8W9"/>
    <dbReference type="STRING" id="48709.A0A1D2M8W9"/>
    <dbReference type="OMA" id="KFRTANP"/>
    <dbReference type="OrthoDB" id="5983381at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050938">
        <property type="entry name" value="Collagen_Structural_Proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456:SF5">
        <property type="entry name" value="COLLAGEN TYPE XIII ALPHA 1 CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456">
        <property type="entry name" value="SI:CH211-266K2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0176">Collagen</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903637" evidence="2">
        <location>
            <begin position="22"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="499" mass="51357" checksum="859083255FBFB746" modified="2016-11-30" version="1">MVLKSYVVILGIVIFTESTSGLNFHHEKKLEFPLEKLQLPQSSRSQFRNLEEADNKYEIFMKLGNGVTVGCEVEKKPEYDDIVELYLEDEFGRREPEIGELAPVAKFRTANPLFRDPQAAADLLETEVPYGWWPAECIQRIMGLQLESNLCNCPAGPPGLTGRPGSEGLPGPAGPPGKDGRNGTDGQVGPVGELGLQGPRGNKGPKGIPGGQGIPGPVGPAGPAGNPGRDGRPGSPGSPGASGQDGKPGRNGINGRNGRNGVTGPPGSPGLPGNNGVAGVAGLQGEQGIPAPSGANGENGANGLNGLPGTPGANGPCNLPLPPGDDDDTIIIDITDQPGEPEIPPPDDEIPVEEPPSPETGWLAASEPLENSWVSPAPPKPAKPLQTQQNAPSISDLSLTPSSNGAKPAPWSGGSNGQLGAVGNSYWKNSATRSSPNGAGSKPKCAGKKKRGKGKKKAQGNQPLSAESISTPVVVVAPPVADELENVPPRARVDLELEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9M0</accession>
    <name>A0A1D2M9M0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-60S ribosomal protein L40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002460">
        <property type="protein sequence ID" value="ODM89670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9M0"/>
    <dbReference type="STRING" id="48709.A0A1D2M9M0"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="176"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="498" mass="56056" checksum="550F78459E737649" modified="2016-11-30" version="1">MTMEKLQVSHITRNINELIFNTKCNTGFLALLLEKGVLCDNDVDTLDKVLRLRFKLLYPLANNKKPKGGLCTVTNQTGAAKILNDGVPEDARRSRKIARVFKRHVEIPKPSYNVIIRGLNGEPFSKAYLSDLGILPKDWTLRYLNEFLPIDTDLKTILCDSNFPLYINTNEGSKLLTIFVQVPGNLLRLTVPDNVSCAYLKFFVYQKTGKHWTTLRIIFAGKDLEGERTIRDYSIKDCSTLHVVLRLQGGVGLTDLEGNQKSGVGLPALKEWEGYGKGINPIGECLNQSCPTQINNGETINRMGYELIRLSGNNKQVSCVACKSPFTPENFLISCGRSLFRFKAQNSGEIKSVVLESLEGHEKYKIFDPAENSFEYDNIEIITVRDGWSLKFCIFCEGEIRNDDEFMYKCQHASHKLCAKNKECCLCKANFISAEEFKTVIQPQKLKVKRKNEPMDCTNSEKLVTDDRGGNFFGGKSLQVVVLVGLLGVLVSFCILKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB13</accession>
    <name>A0A1D2MB13_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lipopolysaccharide-induced tumor necrosis factor-alpha factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16522</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Lysosome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CDIP1/LITAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002136">
        <property type="protein sequence ID" value="ODM90160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB13"/>
    <dbReference type="STRING" id="48709.A0A1D2MB13"/>
    <dbReference type="OrthoDB" id="4713066at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098560">
        <property type="term" value="C:cytoplasmic side of late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098574">
        <property type="term" value="C:cytoplasmic side of lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037519">
        <property type="entry name" value="LITAF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292:SF6">
        <property type="entry name" value="FI16602P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292">
        <property type="entry name" value="LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="9">
        <location>
            <begin position="53"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM90160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15588" checksum="5FAA3B18C60EBF0E" modified="2016-11-30" version="1">MQNASHHQHHDEIISDFKSRFTVPPQPQPLTPFPHMNTAPQQLLLEEELPPLQPVLPTTPPSPPGLGSTNVRLTCRYCRNEIQTIIEKKPSMVAWISVGVIAICGGIFGCCLIPLCVDSCMDTYHTCPTCGAPVGKYKALDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB29</accession>
    <name>A0A1D2MB29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002117">
        <property type="protein sequence ID" value="ODM90197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB29"/>
    <dbReference type="STRING" id="48709.A0A1D2MB29"/>
    <dbReference type="OrthoDB" id="30931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016922">
        <property type="term" value="F:nuclear receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46232">
        <property type="entry name" value="SMARCE1 REGULATOR OF CHROMATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46232:SF1">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="42343" checksum="18B5845FD4C3AA53" modified="2016-11-30" version="1">MLRNLPALDKLEFVAEYEAEKVEYHRALKHFRSSPAYQAYIQAKAKAQKELSENSERSASAKQSAAERRIEIQPAEDEDEQDDMFSEKHKAHSRYLRNHRLINEIFSDTIVPDIRSVVTTARMQVLKRQVQSLTMHQKKLESELQQIEEKFEAKKRRFMESSESFTDELKKHCKRAVDEDTFQKLVDKQYEVLKKEFEERAKSLPPPPPPVQQQPPPPAAKGAAAVGIDDKKDSEEDVGGTKTKDGEQMSPNEGDKKVDISKTSAISINTQSALPPEPTEHISPTPTTTASATLVEADKPVETEATQLESLETSKKSLDVQKMEVDEPSQLQPPVSMVPAPPTVWEAEIQHHAPPPMESESLAPPSLPNQLCCDCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC29</accession>
    <name>A0A1D2MC29_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metalloendopeptidase</fullName>
            <ecNumber evidence="7">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16208</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6 7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01001946">
        <property type="protein sequence ID" value="ODM90472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC29"/>
    <dbReference type="STRING" id="48709.A0A1D2MC29"/>
    <dbReference type="OMA" id="RCALGNI"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811320" description="Metalloendopeptidase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="9">
        <location>
            <begin position="74"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="285"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM90472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="354" mass="39495" checksum="C81B42076C0EC8B4" modified="2016-11-30" version="1">MKTFPLLATLFSLLWGVHRILGVPIPNSWGTSDAKNETQDLYMLDQGSTFRDYNDSNEYIIVDDMIIQRGPSRSGLVNSAWPNGVVPYAFHSTINLQQRRQIIQAMSEISAITCITFRPVTRQDRYNLLFINDPNRGGCSSLVGWTNQRNQQVQISTQCSLGNAIHEIIHALGFFHEHTRNDRDNFVRVNFENIVTEPPGVSNNFRKDSELNPDAEFSYFGVPYNYDSIMHYGKTFFSKSADLNTIDVLYNPDAIGNGDKIGQRDYISDGDVQEMQRQILNLHKAARGQPTSANPATSAPATTTTSQSTASTPRTSVAETQTETTSAKPNHPICKVQPNLPVCKRKGSSAEAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCB1</accession>
    <name>A0A1D2MCB1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001912">
        <property type="protein sequence ID" value="ODM90552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCB1"/>
    <dbReference type="STRING" id="48709.A0A1D2MCB1"/>
    <dbReference type="OrthoDB" id="6274823at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="451" mass="51181" checksum="F7903C93CAADE2DB" modified="2016-11-30" version="1">MMDTIQQQDPPRHEYLFAQLMEPPRSHPQLDAKVVCTDVHDSGECLDSSMISTFELSGAGDFLAVGDRGGKITIYKEDNLTKRTKFTEHLVFQSHDPEFDYLKSLEIEEKINQIKWVPRSYQDRFLLSANDKTVKLWKVGEMMTRSVENLKDINANNPNHLVLPRVTRGKSQPVASFRRAYSNAHAYHINSISVNTDQETFLSSDDLRINMWNLEVNKESFVAVDMKPENMEDLTEVITSASFHPTQCNVFGYSSSKGLTRMCDMRVAVVCDNKNSKVFQDVPDNRGYFSEVITSIGSLQFSNSGRYVATRDFMNVKIWDLTMERTPVQVIPVHEHLSSKLGELYENDSIFDKFGLSWSKHDEYISTGSYDGLVCLAQRNSNRSSLFAISRDVSKNQVLKPKTVVSGPAEKRHTVSVEALDLDRKVGLVTWGNDNLLFAAVNSSMYVLNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDF0</accession>
    <name>A0A1D2MDF0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Mucolipin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_15740</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001736">
        <property type="protein sequence ID" value="ODM90942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDF0"/>
    <dbReference type="STRING" id="48709.A0A1D2MDF0"/>
    <dbReference type="OMA" id="WQARRKF"/>
    <dbReference type="OrthoDB" id="263481at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072345">
        <property type="term" value="F:NAADP-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21050">
        <property type="entry name" value="ELD_TRPML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000033">
        <property type="entry name" value="Mucolipin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049134">
        <property type="entry name" value="MCLN_ECD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039031">
        <property type="entry name" value="Mucolipin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127">
        <property type="entry name" value="MUCOLIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127:SF7">
        <property type="entry name" value="SD02261P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21381">
        <property type="entry name" value="MCLN_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Mucolipin extracytosolic" evidence="16">
        <location>
            <begin position="92"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="15">
        <location>
            <begin position="395"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="612"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="622"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF21381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM90942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="644" mass="73715" checksum="BD5A08029F223759" modified="2016-11-30" version="1">MVKMNNLTQPGRMSINIQDVSRRRQVSQRSAGSNEQPEVEKMRRRLQFYFMNPLEKWHAKRQFPYKLAIQLIKIVVVTFQLCLFATYRYANVNYIMDNKVAFSNLFLKDWNSDREITTYPPTDGPFAIYTKDDFYQYIDFTVNAYANIEDLAIGSYFYGNPDGTIAPVQFCQTNYATGVIFGFNESYIFDSTTEKKCVDIPSAILDAAYNFSSEKFFQDQNIPISFDSLLDAHVMFTLKTVRFRDLGPLKSPDCFQFDIDILFNNRDHDGEMLIDLDAQSTRLDCSGDLESSLDNQLERFWRSGMNYLVIAVGTLSLVLCCRAIYRAQLLKREAITFFRKYYNRDLNTDERLDFINFWFLLIILNDILIIVGSGLKEGIENKELTGDAWNICSLLLGVGNLFVWFGVLRYFGFFRTYNVLILTLKRATPHVLRFLICAILLYAGFTFCGWLILGPYHIKFRTLSTTSECLFAIINGDDIFGTFASLSSKSSIIWWFCRIYLYAFCSLFIYVVLSLFIALIMDAYETIKLFYTDGFPRSMLEEFVIGADIGNLQQSSSPSAFSSPSGSRAHIPMAFSRQPSIASEMTRRLSMTSLTAGGLLDTIVETICRCNTPSPDGIQETDSAREMRVSHDGDGENDALLESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDJ9</accession>
    <name>A0A1D2MDJ9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15720</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001723">
        <property type="protein sequence ID" value="ODM90961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDJ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MDJ9"/>
    <dbReference type="OMA" id="RWQNRNS"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000008">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000019">
        <property type="entry name" value="transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="13">
        <location>
            <begin position="115"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="13">
        <location>
            <begin position="209"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM90961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="312" mass="33409" checksum="43721964B74653E1" modified="2016-11-30" version="1">MSRVDFTQVHCSNPPEAPLVEDVRAGDQVGLECGLVVGDRVIDIGSEWRTFSNEATEVDPCRVGGAENPLLNGSDLTTLLRGGSGMAAFDKHGNAKYTSRKIVASGDRALMNASKEISQIADRLHLPKTVVDRANNLFKMIHDGKKLKSRSTDAISSACLCIACRQEGVPQTFKEVSAVSQTSKKEIGRAFKLVQATLDISVDAINTGDVMSRFCSHLGLPNSVVKAATAIAKTAEDLGIVTGRSPLSVAAAAIILASQASKCKRSQKEIGDVAGVVEVTVRHVYQLMYPRAVKLFPKDFVFTTPINKLPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDP8</accession>
    <name>A0A1D2MDP8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch-like protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001681">
        <property type="protein sequence ID" value="ODM91073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDP8"/>
    <dbReference type="STRING" id="48709.A0A1D2MDP8"/>
    <dbReference type="OrthoDB" id="6412905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044714">
        <property type="entry name" value="AtSIBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672:SF8">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672">
        <property type="entry name" value="OS08G0495500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="218"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="390" mass="43993" checksum="618304AF78D46B0E" modified="2016-11-30" version="1">MSHRFVAHQQGSAFFMQPLDFGDIAYDYFCRLGCSANFWPARDGETEETKSYFNELKQVIGSRWGGSNSQVEGFYMYLKILNVTSDDGSASSKLFGSVHGKLFKDIYEELELLEPVQLKLEIVFGVPLDTKVIKISTQEMNMSMAPKDTHMAATYYTFEQTFPAPWPVTICDSGVDCFLKSELIYSPYPQPGLQLSPSNGSLQIAVMTKTILETGLHSDFTLISENGDRFPCHKVFLAPSSQFFATMFKTDMMESHMSECRLDGSTQEGVSALLKFVYYQDVQEPLTSSGLCVELLHLALMYDIPTLAHCVRNTMLSKRNSWWDIGGAVSLYFRVRLENGYANLKDKAIQILKTKRARGEIMSNANSHFEDLCVSDPNALKELMQLMFCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME59</accession>
    <name>A0A1D2ME59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetylcholine receptor subunit alpha-L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001600">
        <property type="protein sequence ID" value="ODM91298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME59"/>
    <dbReference type="STRING" id="48709.A0A1D2ME59"/>
    <dbReference type="OMA" id="TIDEIWH"/>
    <dbReference type="OrthoDB" id="5975154at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19064">
        <property type="entry name" value="LGIC_TM_nAChR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.390:FF:000012">
        <property type="entry name" value="Acetylcholine receptor subunit alpha-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="7">
        <location>
            <begin position="71"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="28860" checksum="2A2E2E0984C73D5D" modified="2016-11-30" version="1" fragment="single">IDLKHINQEPGKDQVTIGIDLREYYPSVEWDILSVPAERHEKFYPCCLEPYPDIFFNITLRRRTLFYTVNLIIPTVGISYLSILVFYLPADSGEKVALCISILLSQTMFFLLISEIIPSTSMAVPLLGKYLLFTMFLVGLSVLVTTIVLNVHYRKPSTHKMAPWVRNVFTRILPKFLLMRVPDHVLTTPRVLPNKDTWEEIAFRSSVSFSRTDKTCMLFFILNVRYFSCFPLDLNGNESREGIKKHMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME63</accession>
    <name>A0A1D2ME63_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Very long-chain fatty acid transport protein</fullName>
            <ecNumber evidence="14">6.2.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Long-chain-fatty-acid--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Very-long-chain acyl-CoA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">Ocin01_15499</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:54537"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>tetracosanoate + ATP + CoA = tetracosanoyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33639"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:31014"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:65052"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:33640"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="17">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="14"/>
    <dbReference type="EMBL" id="LJIJ01001638">
        <property type="protein sequence ID" value="ODM91184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME63"/>
    <dbReference type="STRING" id="48709.A0A1D2ME63"/>
    <dbReference type="OMA" id="FHINALM"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000002">
        <property type="entry name" value="Long-chain fatty acid transport protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000019">
        <property type="entry name" value="Long-chain fatty acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006134">
        <property type="entry name" value="PRK08279.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="12 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="23">
        <location>
            <begin position="73"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="24">
        <location>
            <begin position="513"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00036527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00060276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00068795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00078285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ODM91184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="634" mass="71351" checksum="3329D28D6FC43EDB" modified="2016-11-30" version="1">MTTSGLHFFYFILAAIIILLLLGLSVWCIVNRRLLCATIVTLPRDVTALTRLIKILGHFLYLQRNNLTVGQVFDKNARKDPEKVIIRFENERWTNEQVQILANKIANYFQSQGFKKGDSVALFMENCPEYLCMWLGLSKIGVVGALINCNLRLQSLQHCLEAVNCQAVIYNEELSHALQDVIAIGGLNGTPLYSLCPTENSPSITPSIHLRTELEKVKCSQPEIKEKVGFQDVLFYTYTSGTTGLPKAAVIKHSRYLIAATAMFCLNNFQKDDVIYTTLPLYHGAANVLGGGAALCHGVEIVIRKKFSARNFWKDCIHYNVTVAQYIGEICRYLLSQPPSEHDRNHQVRTMVGNGLRKEIWSEFVGRFNISEIIEVYGATEGNCNMGNIDSKVGAVGFIPSYLNWAIPYWLIKVDEVTGDPIRGKNGKVIVCGPDEPGELIGKIERNHPIRDYLGYADKSSSEGKVLENAFRKGDAYFRSGDILVRDIYGYFYFNDRKGDTFRWKGENVSTAEVESVISSLIGLADVVVYGVEVPGTEGRVGMAAIADPEQSIDFDELANEIFTTLPSYARPVFVRIVSQIQKTGTYKLQKTTYQREGFDVTKTKDKMYILIGKRYAELTQNVYDDIIKRKIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEI8</accession>
    <name>A0A1D2MEI8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_15414</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001613">
        <property type="protein sequence ID" value="ODM91271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEI8"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="86"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="132"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="188" mass="20942" checksum="C5A25841CA82E10B" modified="2016-11-30" version="1">MECAICWIPLSEPMSSSSPPDAKRCKSSKKQKSATSSGLCTTPCGHIFHRECLMTWLNLNSTCPSCRNKVQSRKLYPVYLPAVEKKDDKKSANTKPVSKQTPNLAGGDNHSTSQEESKCDEKRTNMQHLDEANNDINEDDEDLDADSDNDDDDAMGESDSESGEDDDSEEEDEDVTTESEDEDDDEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEN8</accession>
    <name>A0A1D2MEN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_15337</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001588">
        <property type="protein sequence ID" value="ODM91342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEN8"/>
    <dbReference type="STRING" id="48709.A0A1D2MEN8"/>
    <dbReference type="OMA" id="HALNDHQ"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001817">
        <property type="term" value="P:regulation of cytokine production"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002682">
        <property type="term" value="P:regulation of immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001480">
        <property type="entry name" value="Si:cabz01071911.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001270">
        <property type="entry name" value="zinc finger protein 583 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF23">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="208"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM91342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="261" mass="30671" checksum="D176955C616FED7D" modified="2016-11-30" version="1">MGNLMEHIQMHTREKPYSCTICGALFGRNDVVQKHTLRQHSAKKQFPCSQCPLAYHNKLQLLRHALNDHQKNITYHKKSVNSPAPKKPKERNHKCAVCHKLFLQKGHLYQHMLIHTGERPFKCKTCGKSFISKVNLAIHEVVHTEQKRYRCLLCTRSYKGLRSLYNHISYVHEGGNKKTKECKICHKLFNWNNELVIHMRVHTGEMPFQCVVCEKRFSDNSNLYSHIRSHHTMNEKPYFCKKCPASFSNSFGLLQHIRKMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFM0</accession>
    <name>A0A1D2MFM0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cubilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001421">
        <property type="protein sequence ID" value="ODM91786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFM0"/>
    <dbReference type="OMA" id="ELIFITF"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903939" evidence="1">
        <location>
            <begin position="22"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="285" mass="31432" checksum="73288BB137B868F6" modified="2016-11-30" version="1">MMPPTSFFVVVFTGLLVPTLSQSVVRRIVLYADYPVVTTCGGILISNYSAIAYKTEINVNPNERCVWTISTPNATGYSLNVISLGLTLQTGQTGITATCVSQLSLTNVTNVAINGTGIVRLPTTCHKLLITFYSGARVFSRGFIIWYNATSGRNSISSSSKDYIFSSSQQHVRYPTNVTSNYTNYELSTFVFGTPGNLYNSSRKTLVIYVRDRLEGTGCWDMLQLYRFRPASGWTSSGQVCGGVESTQWTDDDLMLATFKSDASVVNRGFHISRTTVYNQFGMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG13</accession>
    <name>A0A1D2MG13_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001409">
        <property type="protein sequence ID" value="ODM91822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG13"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="631" mass="70454" checksum="B60AA4066E109711" modified="2016-11-30" version="1" fragment="single">MVINRMSKMTLHKNQGQKRVPLTEDGGAAAKARASRAALDRTSTSRSKTDLRREPSIHSSLAPGGDGGGSSAAGGGGGDSGKTRASKKMYFIIAFGVYAFIAALFFILHFALFIYLWSSKMSFFANPGVGFFTVVPDAFWLMWRFLCGTFVHIVLAGFLILILIGLKKTEGMVIKHQDKLLVWVMVVALIAEYLMFSAVMWYFVSFPVVINGGYADGVTHPYSPGEDLTCYNNHIMNRLPTSRLQFPASIYTHINLRWMIDVSCHNSHWKAYITDHSAVALTCVSFITKLERSASRDCSHATILYIGLLSQLFLDFLGMLFCAAVMYLYAKAVVRSGPGRISFDVSTYQQDMGQLGDFVRRYTGATPSQAKVREVTFPKEKAEQTPPPPPTTAAKEMGAAGSSGSGPEPAKLFRDFARDTMEGFHYNYEKYPLDVCWTGHRYSHKYPRSFELRPRRGTPAPVHSTLHTRDLIYSHLPSHPVLNNYFSTTNGLVHDRKFQDPCVMYPILSKAPAAGNMNYIFPDIEKKMQTTYAGLNYNPAPGVGRSVTKMDFGPKRPIADFDYLGSPYLVTINPPRAVRIPVKGQKPGYYSDEQFSILRKFNPYLSRTKIDFCAPKGSTDYPEMYGIKTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGF5</accession>
    <name>A0A1D2MGF5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spaetzle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001341">
        <property type="protein sequence ID" value="ODM92053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGF5"/>
    <dbReference type="STRING" id="48709.A0A1D2MGF5"/>
    <dbReference type="OrthoDB" id="8197497at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005121">
        <property type="term" value="F:Toll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0021556">
        <property type="term" value="P:central nervous system formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032104">
        <property type="entry name" value="Spaetzle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052444">
        <property type="entry name" value="Spz/Toll_ligand-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199:SF12">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16077">
        <property type="entry name" value="Spaetzle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903997" description="Spaetzle domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="Spaetzle" evidence="6">
        <location>
            <begin position="783"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="885"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="964"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1057"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="643"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="968"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1067"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1083"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1098"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1163" mass="128652" checksum="6D3A3C66A5883598" modified="2016-11-30" version="1">MSRLRTLWLVVVVMFSVVNAQLTPEEEHRLVVQADASVIDEKLKEMPYGVLMAPAPVGEHSLPVPTMDPPLPEVPKKSVQITTASLSGNKGALSERIRNAMKTMKERMRTLQSNRPRLPKKPIEPPKAPKFPRPSSLVTSNPSDLEVAMKRIEIMASRAGFNMSSIPRRSQLQIVSRLAPKLPTKMASAVQEEMETMSGKLYAFLPEPARDPLIEDDQTFLQHFMDQFDSPHTEQDEFYKEVNSHASVPSGSSNHPKMNSFDVSQVSLTDDFAHEPITSLSESVDLTAGYVDSSAPDVHMMPPKYDSGEGDKLPTYSVVDDEGVPLPSALISQYPTHHVEEADPLITLSSEVKQKSEAATAASAPVRSTKSFHVGKSYGVTQAPAKRLPPTIPTIETTTTVKTTTTENSIEEFTVSVPPKPIRVSVITKDSILVNDTQQDGSEGNVRTIKYVHVEPIPSAASEKEEQSAFDKYLASESIAKEVRINPKEISVQIDKESLPSARPSVLTLDTYEPELVSSAEPPTEDPYPLTDEEIAATVAELKKYEAEIHGVRQGENSLEVDYPYRLLTPHPLEYPDHPDHPQPSSLEDDSDLVSHLDELLAEFKENSRPTEGSKAQVGLASTQMQATIVPSPSTPPMMFAHGHRRPHPLLKHRPPLRPGMGRPMMMGSRLRPLLHRPPAGFQRPQPMQNPPKINEVTVSQLPQKFNKECDYFSDELCLLVQDYPIEAITEAMDQNPSVSSALLSKEPAHNQKSSSYMDGLEALDSNEGEGGKHPDFAGEGGFLCPSKVAYGKIKKAKSSTTGDWKFIVNYADKSQTLRLEKCLSPGDSCSYIMPHFRTACTQVYNYHRLLAWDSEKGLHNDVFKVPTCCTCHVLGYYVPGTKKSLPQSPAMPTMRRRDHLGPRPRSTNESHERLFSMMQASPSTTSPLLSQRISAALPTSEDDGLRSLLLQYASLREKITKLKDTKASPSPTVASATATSSSTAKRSSKMYSHWPKDIIKALRKRKRQSTISLKNNKMKKPSPEMLKKLKNLLANSTKLENNPKLKAKIQTYLRQLKNASGSSSKSKSRASRGGRNMKLRLTTGTSNSTKLSKTQSKKVDKGVSKSDAKKRLMVLLSAAKNKMKEDNKAAKALASSSAATLNRLTPQQNHHHQHSQEIVKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHM9</accession>
    <name>A0A1D2MHM9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001211">
        <property type="protein sequence ID" value="ODM92518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHM9"/>
    <dbReference type="STRING" id="48709.A0A1D2MHM9"/>
    <dbReference type="OMA" id="ECIRFAT"/>
    <dbReference type="OrthoDB" id="5912242at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006149">
        <property type="entry name" value="EB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069">
        <property type="entry name" value="ECDYSONE-INDUCIBLE GENE E1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39069:SF8">
        <property type="entry name" value="FI17111P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01683">
        <property type="entry name" value="EB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EB" evidence="1">
        <location>
            <begin position="138"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="268" mass="29694" checksum="F5102026D1952DDD" modified="2016-11-30" version="1">MMHATRLHHSLGTLVKTIPSNVSILKNQCACQKEKFVAVMNSMLLGQIGKPVCHVSINFIQECRETTQCTPLNSACVFDRNENTSFCLCSVGEYIESEKTPGKCLKIQNELRLPCEEEQQCVSGLGILSECRDGFCFCRYNYAYYDGYCYTPAKLTERCYVDGECHAGVNNYTFCNPSDMRCRCLPGAIVHDNTCYATKYVGDLCNSNVECALSILGNVICDSSTNRCTCFRGYSAEYGNSVCSSASLPQLISNTVAAALMFSVFIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI68</accession>
    <name>A0A1D2MI68_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001180">
        <property type="protein sequence ID" value="ODM92645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI68"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="29311" checksum="A19D1BD46C492E89" modified="2016-11-30" version="1" fragment="single">MTELHSEFNPCCCISVRAGTTLISLYDMRNNFKWLALLCYVWLLFRVMLEISFLIYLNALIGSGIPHFVRYGQELFLNFALQIYFIVVVSMFIRESRMEFNNMRAIKPINIVQGEHEEYLSTDRSNKFFNTATSFHFLTPHESGIDGKLDISTPTVTITHSPQKDVELNNEDSVGTFAPLKGEYKDQPRSSSDIIHQDASGIMLYSAVNDFQAIQDQSTVSLEELPSLVRAFNTKEQQDEYEKTIKTNVKSGKESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJT0</accession>
    <name>A0A1D2MJT0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleic-acid-binding protein from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001033">
        <property type="protein sequence ID" value="ODM93269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJT0"/>
    <dbReference type="STRING" id="48709.A0A1D2MJT0"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="516" mass="57506" checksum="E74AF8D67AF89C8A" modified="2016-11-30" version="1">MPTEVEEGSTPIKPKWNSSAVSMSSNTSLNFGEPETSFSKSYLDGSKMGDIEEDILTTELEAETSCMSVDENETSGASSSSVHVKSRLSGDSGISSLGVEHLHHEVVSTPKRESPAVLPDFKHKISIYSKVSGCRMTNLTDYWIVKQVRVAILQRLTDGDPVKTLSYKFGYEKMANGGLQIISDSQQLIEMLGNLSYFAGIPCKMTFPDTPRVVGFIKGLPTDLEPSDLKDEIRKTYPQVYSVRYVTEKSRGFAHGIQRPCAFISFNLKFLPKSVKIFEETFELQVPNPMQCTRCCRYGHQGKQCRAQARCSFCGGTHQRQLCTAKAPSCINCQGEHTATSHDCVIWQQGKLMNELRYRGGMSAESAIGIASSGKISQKKHNFIQADFFEEQENYFCGRVENLQGDDDVEDAENQPAPSPKGKVSSVHPRTFRTFPFLDLMTDFFLRAKNPGSNYNSSILMPGYDDLGFPVNRKSKKNTAVAQHFKQTVMAMIDDSPIRYGFTNNQGAEKRDISFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKD5</accession>
    <name>A0A1D2MKD5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000994">
        <property type="protein sequence ID" value="ODM93428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKD5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="9901" checksum="592B5B278A62FDCB" modified="2016-11-30" version="1">MAVFVRTQLIHHNGSNPNTISVATTPGSQIHVGSDSIPRLGLQHATKYAQMKATRVVDVKKPTASVLAVFQGALCGIDIHLHLNNLTFQTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLG7</accession>
    <name>A0A1D2MLG7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Epoxide hydrolase</fullName>
            <ecNumber evidence="6">3.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_12796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O = 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol</text>
            <dbReference type="Rhea" id="RHEA:55764"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:139161"/>
            <dbReference type="ChEBI" id="CHEBI:139164"/>
            <dbReference type="EC" id="3.3.2.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cis-stilbene oxide + H2O = (1R,2R)-hydrobenzoin</text>
            <dbReference type="Rhea" id="RHEA:23900"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:50004"/>
            <dbReference type="ChEBI" id="CHEBI:50014"/>
            <dbReference type="EC" id="3.3.2.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.9" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000897">
        <property type="protein sequence ID" value="ODM93886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLG7"/>
    <dbReference type="STRING" id="48709.A0A1D2MLG7"/>
    <dbReference type="OMA" id="WVKQKYH"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="8">
        <location>
            <begin position="51"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM93886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="50450" checksum="DDE417E025EABB7D" modified="2016-11-30" version="1">MGLLTKIILLLIPIGVGYIYLKVTKTDPIPHVEDAYWGPKSEQGKKEDTTIRPFKIDISAAVLDDLKTRLTRELDSDRLVTPLEGVGFGYGFNSIFLKTVGNHWLNKYDWRTREKLLNQYPHFKTKIGGLDIHFQHVKPKPKNGVAPRPLIVLHGYPGSIIEYQKIIPLLSEPKNSKYNYELIIPSLPGYGFSSGAARPGMGTVEMANIFKRLMDRLGHKKFYAIGGDWGAVITSDLATIYPDSVLGAHSANCVSLGVQGHLRNFLALTFRSIFASPEEEEHKWLSWGETFSFIVRESGYLHIQATKPDTVGTALTHSPLGLAAYIMEKFSTWTNRTWIDRDDGGLLEKFEMDELLDNVMVYWVTGSITTAQRLYSEGLIPWSGINVDDVPTNVPFDCHALSGDIIVVPKFAISHKFTNIKRYKVNAGGGHFGAFEIPSVIAADAVSFFDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLN0</accession>
    <name>A0A1D2MLN0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12880</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000910">
        <property type="protein sequence ID" value="ODM93801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLN0"/>
    <dbReference type="STRING" id="48709.A0A1D2MLN0"/>
    <dbReference type="OMA" id="WEIRITI"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF22">
        <property type="entry name" value="PROCTOLIN RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="105"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="402" mass="46823" checksum="A5B435340276808D" modified="2016-11-30" version="1">MVFNVTPDSTDMNSSLYFLNSSYLSPEEEPDTVQDYPANIYDLFKCSPPFNGHFWPRLLEELEERQGENADCENDISWEVSFRDSSRFWVQYVFFPIVVIIGVMGNAVTIYILTRKPMRSSTNVYLTALAVSDLLYLLFSFSMSWRHFPIVNTIWFYWWYSPIGLWITDASSSTSVWLTVSFTVERYIVVCHPMRREMYCTEQRALWVSIVVYMTCFALTASMPFEWNVAIAANQTGPLNETIYTLEITDFGNSVTYRVFYHWFTTIVFVVMPLVVLGIRNFFLIRAVRKSRLARMHMMNEAISSVLRLQAHRWEIRITIILIAVVIQFLICQLPAAVVLIYTSIHIPDRSSAEESILFGLGNIFNLLVAINAASNFVLYNFCNKYRKRFCALFGVRRRKFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMF1</accession>
    <name>A0A1D2MMF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000842">
        <property type="protein sequence ID" value="ODM94209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMF1"/>
    <dbReference type="STRING" id="48709.A0A1D2MMF1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904260" evidence="2">
        <location>
            <begin position="18"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="199" mass="21877" checksum="85B4981993405C72" modified="2016-11-30" version="1">MLRISTCLLLAVGCVLAAPGPSNKISPELQNQTKANIIVSFVGGTKSTLQSINLQRFESRTLRLNALHDALVANAEQSQRSVLKLLSTHSNKVKSFWLTNLVYVKDADSELIQAIAQDDQVESITEEQIAHLIEPVDMKKVEALADEHQWGVVKIQAPEAWQELGTLSGEGVIIATVDTGVRGTHEALKGQLCWRIWMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMN2</accession>
    <name>A0A1D2MMN2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Patatin-like phospholipase domain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000826">
        <property type="protein sequence ID" value="ODM94320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMN2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="592" mass="68125" checksum="D28C2544BB5F0244" modified="2016-11-30" version="1">MRNDTKVVLEQIEAKALKRGERHRFTQSEDVMAVERVVSMDEIMTFFKASELVNMEEGQLIFGEEDSEQYFYGVVSGEIHLFCEGFGNSGLELLKVAGSDECIVSLSAFLHYFAVGPQTFGELKLHAKCGQSGNYYRVPILELIRYVREDKRKMNEICKTILIRQQKFVLGLNDLTGIAPRLHTQSYLDPNYTPIDVEPGVLELDSPLAHQAFEGLQTLFQLPLEDRRLCWVGVLDSRTMLLRRFKQAKYVFYLHDGMVACTVSKLRRSYNAVQFYLKGGEMIGWREAVVGLDMDIQFQVADGAKAIVVAIPDFVVRSHFEQNPEICVPLIAKLFNRYGLPARQICYALRYTHKRANEVIYKLRFLLDAEETKSGPSVRYGIIEKGDWFGMVAMYTDSPQVHRTVVCDRYCDLGIMPRYVISVITSAFREAAGYQVDYMARCIHRDYENTPLDTDKMHDSRFQVDSFGLHTWRSYRMVCVYPSSSEIPAKIYCDELARHHTCKANVVTKQDAMNSLRLSEFTPENEYALAKWLVCEEEKCTVMFIIADNDFNDLWNETIARICDMVQVLVTLHQDNHKPDEVIVTFHNEISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMV6</accession>
    <name>A0A1D2MMV6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000848">
        <property type="protein sequence ID" value="ODM94175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMV6"/>
    <dbReference type="STRING" id="48709.A0A1D2MMV6"/>
    <dbReference type="OMA" id="YFEYETN"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904294" evidence="2">
        <location>
            <begin position="22"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="172" mass="19577" checksum="282E1D7C778CE0C8" modified="2016-11-30" version="1">MVKISILSVLALAFAVSSIEGRSVIAAQEIDRIGGFLLYRVYEGRIQYLLLKKVDENDWSPPKGNLDEALNESEIDTAVRETREETGLVIGDYGAYVQYKVYFEYETNDDELKKVNLWPAELHNLEKPIQLSPENGDYKWLEFDTAITTIKRQYADGLRQGDALVRAIETTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQJ8</accession>
    <name>A0A1D2MQJ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LYR motif-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000706">
        <property type="protein sequence ID" value="ODM95138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQJ8"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20262">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045293">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="16405" checksum="6BA44EAE3D6D1A16" modified="2016-11-30" version="1">MPSLTFVLQKFQKPPMSLKQFMLRSEVLKLYRGFLRLGRLMDTPSPSTASAVHETNSKNANTRNLHPLQLEWISWVRSEFRLRQNTTEEELVRMMLSHGKRQLQEMERTILLATNRNSPSSTTKPDAENTTKIQDKTNKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR58</accession>
    <name>A0A1D2MR58_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Actin-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11089</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat AIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000647">
        <property type="protein sequence ID" value="ODM95590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR58"/>
    <dbReference type="STRING" id="48709.A0A1D2MR58"/>
    <dbReference type="OMA" id="FMLSHRE"/>
    <dbReference type="OrthoDB" id="2306at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040011">
        <property type="term" value="P:locomotion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856">
        <property type="entry name" value="WD-REPEATCONTAINING PROTEIN WDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50960">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="443"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="524" mass="57771" checksum="BF7A52B9C7D3D0F3" modified="2016-11-30" version="1">MSTQRGAPIVLGGDPKGKNFLYCNGKCVIIRNIDDPSISDTHTDHYLFSPSGFYISSGGNWQMEFMSLCLIHWTVENLGHCHTVNKEHILKSEFTPFRGPIKDISWSADSQRMVVGEGREKFGHVFMSDTGTSVGEISGQSKPINSCDFKPTRPFRIITGSEDNTIGIFEGPPFKFKMTTTDHSGYVFVVKYSPNGELFASGGFDHKVFIYQAKDSQLIGQVGSPAHTGGVYGVAFSPDSKQLLTASGDKTCKLWDVETRQLIATFPMGNQIDDQQVSCLWQGPNLLTVSLGGFITYLDVNNPSKPLRIVKGHNKPITVMCLNEDRTQIFTGCRDGFITYLGVLLILENGRKVGSLPLDYEPSCLAINPDSGDVAVGGAMDNNTHVYGMINNCFFEKVILHHLRPVTDVKYSPDGKYLAASDGYRKVVLYSAEFYGPVNNKEWRCHSAKVNCVAWSPDSKLVVSGSLDTTLIVWSVEQPAKHLVIKNAHPKSQITRVAWLSNSSIVSTGQDSNTKIWEIAGFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR59</accession>
    <name>A0A1D2MR59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000652">
        <property type="protein sequence ID" value="ODM95567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR59"/>
    <dbReference type="OrthoDB" id="10250638at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904419" evidence="2">
        <location>
            <begin position="24"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="316" mass="34741" checksum="DAB6B865BB7BA58A" modified="2016-11-30" version="1">MLVKYWLPVAVLVAAQVVWTSWASAPDPTNVNSEESKEVGETADLEAQELFLRPVVIKYGHDHPAVYTWQGASGQGQGWGVYSQTQNQGLQQGGQQPGWGWPPKKGWGKEKKKKKKKKGKKKKKKAQKKKKKAQKKKNKAWKKSEKKSEKKKGGDEGGWGQVEEPGWGGESEKGGKKKGGEGGWGDDDDDDDGGGWGKEKKKKSKKSKKKGGDGGWGDDDDDDDGGGWGEDKKAKKKKSKKSKKKKGGGGWGDDDDDDGGGWSRSRQQNEQYRFNLAQGVQRFGGVADTVEYIPVVPADALPFQGFDGYFQDAYMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRP0</accession>
    <name>A0A1D2MRP0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000638">
        <property type="protein sequence ID" value="ODM95666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRP0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="347" mass="40528" checksum="10D8ABF93D0567F9" modified="2016-11-30" version="1">MKQKNKIRSYADCISMDRRFTYVVNGRVHLHDKESARKMDERQAYWMKNTLICSYKGCTRGFLSMKALWKHRLEHIAQESSYKDQEHGDEVEEKGVWAEIIEELSAKLSEHKEEDNCNEFEPLLEKLPETEEEDTRNEFETLSENLPKTEQEDIRNEIEVNLPEEKPPTLECMVMDNVKNELSSVPRLDESEYAMNPFKGIPELDFHGYDDKATYSTDLDVEDTETEDSALGDSVVERMDTSDDEDNPEASLEGDYAKYLEMVENQEGSVLVADVKKYFPNHRCMLCKHCDTYYFNISFLRLHYTHVHPKKNISYLCEETVTTYDLPIVMNAAGPCRRYTSNVVDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSZ1</accession>
    <name>A0A1D2MSZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000588">
        <property type="protein sequence ID" value="ODM96052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSZ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MSZ1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="127"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="310"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="477" mass="54180" checksum="AB3ABA565CE5547C" modified="2016-11-30" version="1">MLSVPAVQFFSLKFFVFAKKNVVIDLEYFFYTLCSDELIAFLVILWIGYRVCESRLNILEVISYRNMERVRLPFVVSRRELMRIPDCDNRDQVVEGRGAAAVANLEPVDSPYMNADILGTTTIECEPFTFLWTLNDYSKLSALGEIWSALFYGDSKNNHAWQLKVVPKQRASPEEGECLGVYLCLKEFGSGENTYYRKIRARYQIGLLDPDGKMSTSRGYRSMNAVEVMKNALWGWDKFISLGELHSPYRRLVVNDVLRIHCTVWIEGQITQSLTVKGRGVALTKEEKVLKNRTILAEEFGNMFKNSVGTDFEILVDTPGGDQAVDVIRVHKAVLAARSSKMANSFAIGMYKDNRMTITTFNRTTVSGMLEYLYTGSVDQAVMNEAAPDILQISEMFDLPELKEECAFQISNHIEIQNASEVLLLAHLYNTDWLKAQAVAFINKHKEAVMKTQSFREVLTRHRSSGIFADLFVADGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT52</accession>
    <name>A0A1D2MT52_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Spectrin beta chain, non-erythrocytic 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_10407</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spectrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000556">
        <property type="protein sequence ID" value="ODM96280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MT52"/>
    <dbReference type="OMA" id="DAIMEEC"/>
    <dbReference type="OrthoDB" id="9942256at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051693">
        <property type="term" value="P:actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21193">
        <property type="entry name" value="CH_beta_spectrin_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21194">
        <property type="entry name" value="CH_beta_spectrin_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10571">
        <property type="entry name" value="PH_beta_spectrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000001">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000007">
        <property type="entry name" value="Spectrin alpha chain non-erythrocytic 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000024">
        <property type="entry name" value="Spectrin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000043">
        <property type="entry name" value="Spectrin beta chain, non-erythrocytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000279">
        <property type="entry name" value="Spectrin beta chain, non-erythrocytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001605">
        <property type="entry name" value="PH_dom-spectrin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00683">
        <property type="entry name" value="SPECTRINPH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00019">
        <property type="entry name" value="ACTININ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0117">Actin capping</keyword>
    <keyword evidence="10" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="17">
        <location>
            <begin position="44"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="17">
        <location>
            <begin position="165"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="15">
        <location>
            <begin position="827"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="16">
        <location>
            <begin position="2948"/>
            <end position="3053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2845"/>
            <end position="2933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="3061"/>
            <end position="3178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="737"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1862"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1948"/>
            <end position="1982"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="2202"/>
            <end position="2229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="2327"/>
            <end position="2386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="2740"/>
            <end position="2809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="2884"/>
            <end position="2912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="2919"/>
            <end position="2933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="3061"/>
            <end position="3075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="3155"/>
            <end position="3168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM96280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="3271" mass="376054" checksum="7647DD5FEE50B057" modified="2016-11-30" version="1" fragment="single">VSFEVKNQVPNATTRLKENLKRVREDALKFETGRIKALQEERLHIQKKTFTKWMNSFLVKARMEVEDLFTDLADGKKLLKLLEIISGEKLGKPNNGRMRVHKIENVNKSLAFLHTKVRLESIGAEDIVDGNPRLILGLIWTIILRFQIQEIEIDVDEENESSEKKSAKDALLLWCQRKTKGYQNVNIQDFSGSWRSGLGFNALIHAHRPDLLEFDKLVPNRHIDNLNNAFDVAERGLGIPSLLDAEDIDTAKPDEKSVLTYVASYYHTFAQMYNKDKSGRRIANIISQIKEADDLKYKYELDGKNLLAWIRATIKELNSRDFPNNLEGVQKLLQKFTEHIADHKPPKYNEKSEIEANYFIINTRLKELNQHSYTPPEGLLVHDIERAWAELEKSEYLRELALREEVIRQTNLEQLAIRFDKKSMLREGYLKDMIQVLSDPRYGINLAQVEATLKKHEAISADILAREQRCEQLVTMAEYLVKENYHDCDRVRARAEEITRTWGELISLLDTHKINLEKFSMLMQMIRDIDTILTTIQDLQEIFNSHDVGVHLIGVEDLLQKHSLVESQISSMGDIKRIGKQAANYAGKELSTIEPKIKLMNTEYGNLVKSSKERRNKLEDSKAFFQFVQDCEEEDAWVNEKNRVVCQAISCKDLRGVMSVIGGHKLLLDELKARKGQHNKIVEKANELCRIWEAEQRGVKDLEIKDFYSDANEMDSWVTEKRPLVSSSDYGEDEPSAQALLQRHVNLEEEIIAYEVDIKGLNSQADKLVKAGINSIQEVSATETPAHSNGIEHSAEEYVTEQKLVPEEYYEDEEIERTDYKTVTEERAVPQVKALYAFDGQEIHIKKGEVMFLLNKTNADWWNVRKANGEDGFVPANYVKEIEPKVVMVQVRKPEVVKETKRTKKTRMVLQNVTKPKKPGVQVPISTGTLKKSASAQSNVSQVPTEPITTRTSRINNDYKDIISLSAIRKQNLQESIKLFAFLRECDDFEKWINEKKKYLQTNEPNVQVAKRAFEKFLTDLTASNNRIQQIDTLVEQFENSKSTNPKTMAIVRARADKIKQDYEDLISLKSKKEQSLEGALSVELFNRTCEDDWMSEKMMQIDTDEWSNDLKTVQALQRKHNNLERELAPIQEKVSRVNLLAESVKKSYPNETDNVDERRIQVINTWESLVNKASGRKHALENAVGMQIFISGVKNLVHWVSGVKDQLNAYVPSRDVSSAEEALKIHSELGDEIKSKSHEFEELSELGKTISSGNVNVQEKLELLANEHEAIHRGFGEKTDWLNQVLDLQMFLREADHIDSATKNHMQFVSNTDVGKNLDEVESLIKRHNDFENTLVAQDERLKIFDSMGAKLIDAGHFERDLINERRNNVIEKKNQVKELAKSRKLELGRSLKYHEFNTDVEETIAWVNEKISVARDESYKDLSNVDKKLKKHEAFAGELRANEVRIKSINRSGDKLVEVVPEKETEVRASVGKLNALWDELTRLSDEKYDKLRQAEAQAGFNKTLDSVVDRLEGIRSNVHTDCAVNDRRSCKDAVKRANLLANELGAVDGKIRELENVADDMEKDGHFDGERIKDKVREAKHNMQLLVAPVEDLKKNLDEKYAYYSFLHELEAEISWINEKRDLVEREVQIQDLYQAQTCVKKHKKLEQEVMNREPIVKKIIEKGDDISKMHPHVDEKLKEFQDSWDALKSACVGKNKKLDLSLKSQQFFFDAGEIEAWMQEKQNLLASEHYGKDMHSAVKLLTKHKTLELEMDSYNGLVTEMKHMANQMVSSGHPDSKVISAKIGNVEDHMGLLKKLANERREKLIESVHTLEYFAEADEFLKYVDEVFGREVSCNEYGSDYEHLCLLQARFRDVEHKVEGTNERFKTLEDMAARLRNLQVGRDAVEAKNRDVGEKWNNMLALMAAREQKLHAPGKYTGSTGTWLTRWRESRRNSTPFLTLVNSCEGMLRQHEAFENDLLALEAQLQVLVDDAARLQQLYPTNAENIRQEQSLVIESWNNLQTRASLRKEQLQNAVDFWRFSAEYASLTSFMNSLLTTLPSQPKVRDTASSQALMTEHERIRSEIEAREESYDHVLQLAHAMVSESHPETDEVSRMVSNLKNLKEKLLVTWEHKRVYLDQLIDLNIFLRDAKQLETNCSGQEITLNSEQLGDSVEETDKAVKKHEAFDKLIHTQDDKFKTLDSQGNKLIKQNHFDSKTVEERLKDVAAARNKIKRLCEQKRQALAARYKYVQFIRDVGETTAFVDEKIKKLIHDSSVNSSLTLQEKIKKLKKHQAFSAEVNSNRSRSFYDEANELTSWMSEKHAYVQNVECKENENVSSLLKRLEAFQRDLGNFYARIEKLQKNGDELVNRNHFDSENIEKKIQEVTHEYSELQKRSDKKRCRLLDAQKFYDFNRACNETVDWINEMMNIAGSEEYGRDVEHVESLIQKFELFMGNVQEGRALHVQNLADELVEEGYPEPERIRGRAAEVKSSWEEFKELAAARLEALQGAKQVHAFDRTADETIAWINEKHAVVCSEEYGHDLESIQALIRRHHVFENDLKPVESKVNEVRSEADRLRSLFVDASEHIDVKLQACLDSWKELVERTRTRGDKLNQAENMQAYFDKYTELMAFVNEMVAKVTSGELGNVQAAETSLAKNKSYSQQIDSFKGVHEFVHRGEGLIKQGHFMGEEIHEKIRVLSGRWEYLNKIVDERDVLFKQNLDLRVYLVQLEDFDKWLNGKEPELKYANLGESIREVEELIREHDEFASTLEAQEARVEGLKRKTLIEEAWENMKKREEAERELQVKRMEKERAELLKRKEVERITNEINKKREEDSVDTSSVATAPRGGFLGNTRFGSFVFGRDGRRGSEPVPASPKEDLSQSPFLKPNATPPPSLIFTDLSSQQQNEAAPQGLSRSESLRLLNTTPDLDSGTLKKPKRTPSFTTRRRTASFRNKKKLAENLPPVEIEGYLERKHELQAGGKRAAVRSWKHYYVLLCGQLLCFFKDQEDFELSKVGSSSPISVYLAKCEVASDYTKRKHKPTDGSEFLFAADNHEVMDAWVKKINFHAVLDPKNQLEKMDTEALEQSDRGRMMPPPPPPPKTRAYESSSTDEDEPCPRKPKPRSNLQQPRSREPIYANNEVERRDTPLSEPPVQLRSPSSTTAAKPPIPPRSSSIVEPNGTNRSPAKHNGSGDAIDNQQYFHTSQAARPVSVDRMLYQAHSVQQRYYNSGPPVSHLPPAPLPRSMNTTFKPQIHGATTTQPPYIHTRGSSFSREFIPISVNSSVIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTL0</accession>
    <name>A0A1D2MTL0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 2D9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10299</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000545">
        <property type="protein sequence ID" value="ODM96383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTL0"/>
    <dbReference type="STRING" id="48709.A0A1D2MTL0"/>
    <dbReference type="OMA" id="CETWIDP"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM96383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="28784" checksum="156240A8ADDCE4DE" modified="2016-11-30" version="1">MDVFLHEIDHHKTEKITPNYYTDEQFAMVLVDLFITGFVPTASCLEFLIMFMILHPEIQKKCHEEIDMVIGRSRFPSINDNEKLPYTQAVCLEVLRHVTFIPMTTRAATKDTQIDDYFIPKGTIAALNLYGMHHDKQTWENPLEFNPDRFLDKDGKLCNQDIMLPFGTGKRTCPAEVFARISTFTYFTYLLQKYSFECPSNSAPPDSTPSVGMGNYAKPYRCVVRDRQLVSSNFIANYKDSRDEDCGTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTV6</accession>
    <name>A0A1D2MTV6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-ureidopropionase</fullName>
            <ecNumber evidence="6">3.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-carbamoyl-beta-alanine amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_10167</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>3-(carbamoylamino)-2-methylpropanoate + H2O + 2 H(+) = (R)-3-amino-2-methylpropanoate + NH4(+) + CO2</text>
            <dbReference type="Rhea" id="RHEA:37339"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57731"/>
            <dbReference type="ChEBI" id="CHEBI:74414"/>
            <dbReference type="EC" id="3.5.1.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-(carbamoylamino)propanoate + H2O + 2 H(+) = beta-alanine + NH4(+) + CO2</text>
            <dbReference type="Rhea" id="RHEA:11184"/>
            <dbReference type="ChEBI" id="CHEBI:11892"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="EC" id="3.5.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; beta-alanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the carbon-nitrogen hydrolase superfamily. BUP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.6" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000532">
        <property type="protein sequence ID" value="ODM96517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTV6"/>
    <dbReference type="STRING" id="48709.A0A1D2MTV6"/>
    <dbReference type="OMA" id="HWPFLRD"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003837">
        <property type="term" value="F:beta-ureidopropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033396">
        <property type="term" value="P:beta-alanine biosynthetic process via 3-ureidopropionate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000008">
        <property type="entry name" value="Beta-alanine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF2">
        <property type="entry name" value="BETA-UREIDOPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="83"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00050540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00075038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM96517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="393" mass="43894" checksum="574CA88064F66C60" modified="2016-11-30" version="1">MANSKQEVESLESLLESNLPNEELKQAWRLLYGSEYPPSELTIPKTATELASVSKIQLKTYQFTAAQEQLRPPRKVRIGLFQNQLPLATDAPVAEQRAALHKLAEKAIEAAAQCGVNVFCFQETWTMPFAFATRERLPWTECAESAEEGPTTVLLRNLAKRHNMVIINPILERDAGDVLWNCAVVISNSGQIIGKSRKNHIPRVGDFNESTYYMESTLGHPVFETQFGKIGINICYGRHHPLNWAMFGLNGAEIVFNPSATVGALSEPLWSIEARNAAIANHYFACAINRVGTEIFPNEFTSGDGKPAHKDFGHFYGSSYVAAPDGSRSPGLSRVTDGLLVAELDLNLCRQVKDKWGFRMTMRLPMYAELYTKASKPDYKPQVVSENERPRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU91</accession>
    <name>A0A1D2MU91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enkurin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000558">
        <property type="protein sequence ID" value="ODM96265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU91"/>
    <dbReference type="STRING" id="48709.A0A1D2MU91"/>
    <dbReference type="OrthoDB" id="2123594at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="880"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="915"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="933" mass="107316" checksum="6806765C0D929AC4" modified="2016-11-30" version="1">MPTDNNPTQRTANVNDEIWKDQIRRAVEESQNVPTPQTPLYRTALIAPRVTKSYYDRLKFEEEQRRKQEMLQKRTKSESAIMKELIKKSRDESLKRKGNVVATGGKHSSWPKKKPSMMKGKHDGTRAKSYDDDAELSEGDTDGEQLGRDEAATTGDESVEEEVLSYFDPKFVRAEFKPLLGKSRNIVVGPPKEILRQYFGYTNDEQIPEELQNDDSPKAFILPLRYWKDYNDGEAPLRQRTSFHFFKDVSENKSAISEEKLSLFEPDAELLRRMQVEKDVEPHIPRQPKNYAVDYLSRQSFKKYGMTGSNLNDASPGVLEHWEMKPVNADPGGHIRRNITDRRFKISSVTDTPVKAAQKESKLKERPWYTDDFVEGVDPQDLDKNPTLDGMSGRKGKGGPGEDDDDGKGPRGKHGGRGGKGSRRHSHSPTSDSSGSTSSSSLCSCMDHSSSSSPTSDEEPKKVKSKDAKDPKASESKESKKPKEKLKKGLSKKSDAGISEVDEDEIPEWAKPVNQWKPPKGHKGWLYKSLRKVESAPENLFHGDDDIKSKEWIDAFGKVRRQRELEDEYGIQDKEDDEIDQPDGDDVGGSEEEEEEEEEEEEDPMERLPRDSDIQLSSRPSRRYPEYPVPEQFQYYKSYPLYPTISSERYYEWFSDVNRLKNPKLKKKWLRPGISKSAGSINWDDPKEAAKWHSYGYRRPITKPKPQRDDYDTKDYIYDNARAIMLMPPKKGIPRYVDDRKGTCRLLEPSGLVHKFVYKEEYGKIPQYLAVRNIELGRPEIPDMDKFYRPHRCKFLHGHIHCKLCMRAHPTIRHRRIDWHCDMTPDDYEDALEYRKSRRLIQNKSSMFGRGSTDYCQEDDEDQLEKRLHIVNRGSECGSYDSFDRGPSDQGSFSRASGESQNFFPFQSSNEVITSNNSNGSSGLNLTHPPYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW12</accession>
    <name>A0A1D2MW12_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="3">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_09567</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000471">
        <property type="protein sequence ID" value="ODM97111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MW12"/>
    <dbReference type="OMA" id="EMQQHPH"/>
    <dbReference type="OrthoDB" id="339325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004706">
        <property type="term" value="F:JUN kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF293">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SH3" evidence="11">
        <location>
            <begin position="234"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="312"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="152"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="702"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="961"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1001"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1230"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1359"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="634"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="711"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="820"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="968"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1039"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1051"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1244"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1271"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1388"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM97111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1479" mass="164673" checksum="E5B2B44C4987E461" modified="2016-11-30" version="1">MERIGAYLEELSPMEQPAASRPATNYLLGPYLANGGSRNNGYHYDDEEPLTDASNSRDHSATASLLSAELANEIATKNAKKFRSYSASSSPYISNYRLPNSKHVTNRHHQSRHDESAQKPAFMAMEPMTQYQIHVGNNNVAKASFHRSLGHLIETDDSGGPSDQRGSNNFHHGISYENGGFIRQHQSRYSDRSPRTFKKSSVELSQDCGASSSETIMEERDSDKRDMNNSVNDKVDNIWTAIYDYEPRELDEIPLKRGDFVRVLSQDVSLSGDAGWWVGSVGEYCGIFPSNFVTKVTKADLREPPKISYEELSLAEVVGAGGFGRVHRATWKGREVAVKAVNTDDDIETTIQSVQREATLFWLLRHKNIVALLGVCLAPPNICLVMEYARGGPLNRELAKHRGQIRPSVLLNWAMQIADGMHYLHHGAGATIIHRDLKSSNGKCNDVFSLNFLSSLTKWIHNLCIHFHTLKATVSSFILILEATEPGDDFMNKTLKITDFGLAREVYNTTNMSQGGTYAWMAPEAIKGCQFSTASDVWSYGVVLWELLTGETPYKGMDGLAIIYCVGVQKISLHIPRTCPGSWRKLMEACWAVDPHQRPSFGAIRQELELIAASPFLFQQEEFYSMQESWRSEISEMVMEIRNKERELLSLEEELKKMEMIQQIQQQQQQMKEENLRRREEAIRQRELEVMQREIVIALLSQTSQPTPKPTPKKRRGKFRAKALGKKEASQIISSPSDFRHTLTVQPADRSKGIRSFSSPETPPGSPLPRTFVLPSEGTKGKTWGPSSIHQKERGKIISKVAESPKRWSKSAPNLDKSQKSLSVSSGGPSRSDSCENERLVGSVPFIQLPNSATQEPRRAKKLSPIQQALYNTAAIIAMLTGFDIRKQKNQAQTTSATEEADTGPHQIVFLNKGFQNSGFGDSDSDLNDALTLSSAPAALMGSGKSSHTTYHNLQHQYRPSLWTPGKSDGVSDSSVSQSSMSSNIPHKSIPLIATNGIAHQHDRRNKSATSTPSRSALTTPTHRKYSPAHSHTNESENENVQIQSPSGNRSKPHHGLAKGQHRILPNFEPGLQKRKRGSAGTKHIYFVNENGEVVSVNPFIHETGGYHYTTEEMQQHPHPPVTYFTQTSSRSNPYSSPYRRAISNPSDRMIDTENSYFSSLVTHGLGPSNQRSTNPFISDQQQQQQQHHVYHNPLVYGNQVFEEFSPCDDAFDGRDEVLVGTMSNMRLGSGSGESGYHGAFQDTNPNSPLSSSTSASTNPRTPLRHVSPMYSHQRTPSNLSNASSGSFGMNPSFEGDSIVSGIPAHRSSYEYGYEFRTPLTPKLTPNPQRHQSGNNMLVTERPATLELPRPLRSSLRKYNYSRNQGPSYNWGGDSGGGMTNVETPPDSSLSEDSSYVSAKDSSLASMSSQHSNPVARVRFSPIAMVCRDPMDLPVMDRTMPLQPYRNVHSAGAASRAEYTPKLRKNMSDYGKFEFLRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX95</accession>
    <name>A0A1D2MX95_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS-type transporter SLC18B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09258</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000444">
        <property type="protein sequence ID" value="ODM97424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX95"/>
    <dbReference type="STRING" id="48709.A0A1D2MX95"/>
    <dbReference type="OMA" id="TIIMSEF"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF26">
        <property type="entry name" value="MFS-TYPE TRANSPORTER SLC18B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="27"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="45041" checksum="AA6BCB2F8323CF9F" modified="2016-11-30" version="1">MGAWKTFSKSCCRCACTTRFTRRQWMTLFVFSLAYLFSACVTSLQAPFYPAEAERKGASATEYGLVFGIFQLVCFLISPVYGKYLNKFGAKKIFNMGIFTSGISCFFFGFLDRVEGHFLFIFLSFLIRIFEAIGSTAFVTAAFTIIAGEFPDSVATTFASLETLYGVGLIIGPSLGGALYEVGGFTAPFAFVGLCLISVALSTPWLLPNGKSMDGGDCKDTEGFGIFSILKLPAVQLAAVNIWMATNSLGFLSATLEPHLRQFNFSVLEVGLIFMLTGASYAISAPIWGKLMDKWIHPKYVIVHGALLIMASHVLIGPAPFLPFETYFPMSCIGLILHGIGIGACQVAAFILALKESIANGFPDNLNLYSVVSGMWASFLALGLFMGPSLGGVLLDQAGYRLGSLYPFIAAVVVVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY36</accession>
    <name>A0A1D2MY36_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08714</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SRP72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000392">
        <property type="protein sequence ID" value="ODM97966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY36"/>
    <dbReference type="STRING" id="48709.A0A1D2MY36"/>
    <dbReference type="OMA" id="ELACNER"/>
    <dbReference type="OrthoDB" id="5421607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031545">
        <property type="entry name" value="SRP72_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17004">
        <property type="entry name" value="SRP_TPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038922">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="11">
        <location>
            <begin position="548"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="555"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="625"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="630"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM97966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="656" mass="74110" checksum="09E76E688EC78754" modified="2016-11-30" version="1">MKKPQQKDKASLFSDIDKYLLNGDYERAIKDCNRVLHLAPDNELAFRCKIICCIHLDRVSDAIMFMSKNPKMVGKLGFETAYCYYRLQDMKTAKEILDKCEDSVCKKELMTQILYRMEMYDEAYNSCKEVIRISKDEYDEERQTNLAAINASLIGSGFERRLENVDHHDTHELRYNMACALIGEKRYVEAIKLLKTAEVKAVETLKEEGLSEEEIGKDVAVMTIQSGYCRQKLGRQKEAIELYSKALKNKVRDPDLVAVASNNILCINRDHNVFDSQKRIKAIRADGAEAKLTRAQRRDMHINQCLFYLLTGQADLCKETCALTASKFPETEHEIFLINTALILKTDGIEAAKTFVAPTVGQTEDMQLRISLCFVQQLLRDRNRKDAISILESLAEKSYKPGIIGALVTLYQQEGRVNDAAATLKQAVDFHRKGGGNKKYLNVLWRHSASPMIQQGDLGEAVKSLEELQKSSPDDITTLAQLIVAYSRYDIKKAHKLISQLPPVTPPDDLDLATLESPNWLSSIKMMKKSTKSDSVPATPQISAIAVSVSEPMKKKKKPKCKSKLPKTFDPEYKPDPERWLPKHERTGNRWRKQRRGNLDVGKGTQGVDSATSVAYDMSARILLRKESELSSSTSKSSVGTPKKSNRKGQHGGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY93</accession>
    <name>A0A1D2MY93_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protogenin B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000389">
        <property type="protein sequence ID" value="ODM98023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY93"/>
    <dbReference type="STRING" id="48709.A0A1D2MY93"/>
    <dbReference type="OMA" id="SEWIRIQ"/>
    <dbReference type="OrthoDB" id="438268at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050991">
        <property type="entry name" value="ECM_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708:SF2">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708">
        <property type="entry name" value="TENASCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="48"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="143"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="263"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="376"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="471"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="572" mass="64052" checksum="79F7514AFE38952E" modified="2016-11-30" version="1" fragment="single">VKGNELVVSNTIRNDSGFYQCEVIADDRVYAVGTARLLVNNSREAPDAPTNVECVEKHPTALTVSWKQPSNFKDIHAFSVHYMPLLGAETQRVVARDVSSVDLSSLSPHTNYSIYVRSYSKKSASAQSTLVVCETTEDVPLNKPPIINMERFGPPSQARIFWRPLTNKEARGKIILYKLQWRSVDGEFSNVRYIDGESVEFLITDLDPDQDYELRLIPSTSMGWPTRKDSMPWTPVIVSNLANRNSTNYNQTHSITFDEYFAAPSMHLTVLNSTSALVNWSEPPRPKEISVKGFRITYSTKSERVNDVVFFGPITVYDDNAREHLFTNLVPGATYEFYLQTWGTGWESSLASKFISTLTDSEDGQSVNSGEGMLPLVAGLQVHPISATEVRLKWDQPIINSTDGYFYIVKYNKVDTIEIYILSSTRESVEINGLSPYTSYEFVVQLALKDGRVGPYSQKIESRTLPGIPGVPINLHWRVLNKTIVEVEWKPPSSPNGMITKYWVEFKLNTTAASSQNASSSSSSSGGVVIPHLQRLLLLPRPLLRMGVGQSSRPAILQSSSMSYNLMRFMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZE1</accession>
    <name>A0A1D2MZE1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RUN domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_08266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000357">
        <property type="protein sequence ID" value="ODM98413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZE1"/>
    <dbReference type="STRING" id="48709.A0A1D2MZE1"/>
    <dbReference type="OMA" id="ERCTCAV"/>
    <dbReference type="OrthoDB" id="10068328at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058732">
        <property type="entry name" value="RUNDC1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047343">
        <property type="entry name" value="RUSC1_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15591">
        <property type="entry name" value="RUN AND SH3 DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15591:SF19">
        <property type="entry name" value="RUN DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26030">
        <property type="entry name" value="RUNDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="3">
        <location>
            <begin position="154"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="376" mass="42762" checksum="FAC2E9D66868AC20" modified="2016-11-30" version="1">MDSSFEDRDEGVVNSDEQDPDGDPEEEWDAWEGLKGRPERWAPLGANDTDKEYSAYGSQEEEGPLDPDDLKKMKDDQEQLTSALLALTTHFAQVQFRVQQIVVAPEEEKEGLLKDLEEFTFRGIPSAVTDRLGSGEGPCKIDDIKEKMRIQREKQKDLITQLKGQLEELESYAYQTGDAGLPQSVLLERHKIVVDQLKNRLNLNVDELEKLSDQDLRYQVDQAISDIVSPLKMKEQLVDQLKTQISDLERFIQYLHGETTSDIKKCACTKSKETKEFTHTDMGHEEELRAKTIQMMKKALTLIQMFAVAQFGCSSNQFHMNALKKSAKGNHWGDLRACLEIAITRVYGLAVQADTPATAITLRIVKMHRLYCVTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZF1</accession>
    <name>A0A1D2MZF1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08288</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SRP72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000359">
        <property type="protein sequence ID" value="ODM98392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZF1"/>
    <dbReference type="STRING" id="48709.A0A1D2MZF1"/>
    <dbReference type="OMA" id="NDMKVLA"/>
    <dbReference type="OrthoDB" id="5421607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031545">
        <property type="entry name" value="SRP72_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17004">
        <property type="entry name" value="SRP_TPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038922">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="11">
        <location>
            <begin position="550"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="549"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="650" mass="73154" checksum="0410776E065A7AF0" modified="2016-11-30" version="1">MEKPQQGDKLKSLFADLDRSMSNADYERAIKVCNRLLHVSPDDELAFRCKIICCIHLDRVSDAITFMEKNPKISGKLGFEKAYCYYRLQDMKKSKEVLDSCEDSIGKRELMTQILYRMEMYDESYNSCKELIRVAEDEYDEERQTNLAAINACLIGAGSERRLEKVDHDTHELRYNMACAFIAEKRYVEAIKLLKEAETKAAETLKEDGLTEEEIAEDTAIMIIQSGYCRQKLGRDKEAMALYSKVLKNKPPEVDLVAVASNNILCINRDQNIFDSKKRVKAIRADGADAKLTRAQRRDMHINQCLFYLLTGQADLCKETCALTASKFPETEHEIFLINTALIVKTDGIEAAKSFVAPTVGKKEDMQLRISLCFVQQLLRDGNRKDAISILESLAKKSYKPGIIGALVTLYQQEGRVNDAAATLKQAVDFHRKGGGNKKRLNVLWRQAASLMIQQGDLGEAVKSLEELQKSSPDDITTLAQLIVAYSQYDIKKAHKLSSQLPPVPPPEDLDLATLESPNWLSSIKMMKKSTKPDSVPATPQISAIAVSVTEPKKKKKKPKCKSKLPKTFDPERKPDSERWLPKYERTGYRPKKQRRGKDKDVGKGTQGADSATSAIYDMSAKMSQKKPEPEPSPSTSKASSRPSKKSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZW5</accession>
    <name>A0A1D2MZW5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000341">
        <property type="protein sequence ID" value="ODM98587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZW5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="347" mass="40261" checksum="B65367B881A58B01" modified="2016-11-30" version="1">MSTVSESSETLKETEEPSLLMKVQTTGKDWDNAPNELTQLRALLLKTGYEVTWSPKKFAINLLTANKIRGMVLKRILMKAYPFDLFWATETLDETLHKCLIVCQQLGLEVDRPIIWGQCSMDASFRFWCRLLKMVPRISKARKEEDFVHEAKSKVISSLISFRGTDWDRAIARNFEQGLGRNRNHDFLKRCISSNSFLAQNQKPKQKRGVYNRHDYDEGDITDWRSSLKHILDPESDEGKASTTTSLANELKQESQAMIEALRDVEKYYVENSRLEIEDAFKLGYQVCDLAEEFETYMTTNNRGAFRDVDSLTNHTDKVIKSMSKLATVYGDFYAEFRKYFELKWGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N054</accession>
    <name>A0A1D2N054_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasminogen activator inhibitor 1 RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000353">
        <property type="protein sequence ID" value="ODM98444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N054"/>
    <dbReference type="STRING" id="48709.A0A1D2N054"/>
    <dbReference type="OMA" id="HNWGTIK"/>
    <dbReference type="OrthoDB" id="6022699at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="44900" checksum="CE0CF5650EF43346" modified="2016-11-30" version="1">MEVEYGVGITNRFSFLHEELEDQEVPVVPVKTIRPPEAAAKKGVKTDVKVKKEPKKEKEPPTTNRVARKESSQKVNIPKDEKRDFYQPREKVGDGSYGRSSGPRNNQYQQQPRRDNQRDGQPPRRNFKPRGGPPRDRENVEANENTENSEAVISGEEGRAGKGENELLEQDAKKDDAQNADISGDDQEKENKEDGEKTPEKTLTLKEWKALQAPREKPMFNIRRPGEGEDCTRLGKLVPKKKNDEDIVVPEEEYELDNTYYPQRAGKFKQVADVGFTTGYQKRRGGGRGRGRGFEGGDERGRRYDGEGFEGGEERGRGFEGGDERGRRHDGGEGRGRRYDGEGRGRGFGGGGDGRDASSEENLLSEKTRGRPRYNPRGGPRRGSPPVPRINDTMDFPSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0K0</accession>
    <name>A0A1D2N0K0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing CTD phosphatase 1</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nuclear proteasome inhibitor UBLCP1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_07921</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000326">
        <property type="protein sequence ID" value="ODM98760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0K0"/>
    <dbReference type="STRING" id="48709.A0A1D2N0K0"/>
    <dbReference type="OMA" id="TVHTPKY"/>
    <dbReference type="OrthoDB" id="1711508at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090364">
        <property type="term" value="P:regulation of proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01813">
        <property type="entry name" value="Ubl_UBLCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011943">
        <property type="entry name" value="HAD-SF_hydro_IIID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051658">
        <property type="entry name" value="UBLCP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02245">
        <property type="entry name" value="HAD_IIID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="14">
        <location>
            <begin position="36"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="15">
        <location>
            <begin position="167"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="342"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM98760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="369" mass="42015" checksum="2BFE70E1FBC91DB7" modified="2016-11-30" version="1">MEGSSTEPSPGSSRTATTEGSVNANDSVKDASASPHNLIVKWSGKEIEIEDINGLKTVRDLKQLLQSKTGVQVDRQKLLNLTYKGKLAQDDCILANMGLKVGQKLMMMGSLEKDIESVDIPPEERPDVNNDLDIPDDDEEPLDNREVYLNKIARRVKEYRIHVINPPRPDKKLLVLDIDYTLFDHRTTAETPVELMRPFLHEFLTAAYEEYDIAIWSATSMKWIEEKMRLLGVSSNSAYKIAFHLDYLAMISVHTPKYGVVEVKPLGVIWGQFEQYSAKNTIMIDDLRRNFLMNPQSGLRIRPFRSAHLNRQSDCELLRLGGYLRKIAKLDDFSNLNHRKWESYGGKSHSSKHRRSQNSSGTDSNNSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N206</accession>
    <name>A0A1D2N206_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PSI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000290">
        <property type="protein sequence ID" value="ODM99270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N206"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002165">
        <property type="entry name" value="Plexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016201">
        <property type="entry name" value="PSI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01437">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00423">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904910" description="PSI domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="domain" description="PSI" evidence="6">
        <location>
            <begin position="31"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PSI" evidence="6">
        <location>
            <begin position="107"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="PSI" evidence="6">
        <location>
            <begin position="184"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="PSI" evidence="6">
        <location>
            <begin position="269"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PSI" evidence="6">
        <location>
            <begin position="530"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="PSI" evidence="6">
        <location>
            <begin position="798"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="domain" description="PSI" evidence="6">
        <location>
            <begin position="885"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1038" mass="113789" checksum="13FD4D64B7305B63" modified="2016-11-30" version="1">MANWSVGFFVVLLLACQQVSSKEGSSTTTSFCSDQPSCETCVAQQIRNKNYGNLNPAANCVWEVTSSGQLCVETYTPSQEISNVAFNRPGCYTIPSTTTTQPPPVPTCNEQTTCQSCVSTALNLGTRSRNQATCVWEVTSYSQGCVEEYTPSQEITNVAFNQYGCEQIPTTTTTAPTTPPYRNQCQNEKTCESCVVTRGDTSQPEFDAYGNPNPAANCVWEVTSSGELCVETYTPSQEISNVAFNGNGCKAIPTTTTTPAPTTPPYRNQCQNEKTCESCVVTTFVSFQPDLYKNSASNCVWEVTSSGNECVEKYTPSQEITNVAFNREGCRTIPSVSTAAPPKSDPCLQENVCESCVQTIAASENDSTCLWIVANSEGQCAKTFNLSEEIEKVVYSTNGCQTESNSSSTTTPTPVIPDSGSRCECTENDAIRANSDDQLNEIDDDIVVAEIISVNDEQEKDEFDFFGANVADRLRKVQYSSPKLASSIRYEIQKALFDNEKLLLKAPRRLTGGSTIPSTTTPAPSNMKNQCLNKKTCESCTVTKNNDSFFICVWEGSKYGQQCVEFDNISNGTVFVVTGPNLCPIPSTKTPPPSSPQSVSICTKQKMCQSCVSTLIQTEVVFGNKISTTPSTIVDPCRGENTCESCVQTLVTSELERLSINRPYCLWIATRLEGRCARTLALPHDIENIAFTTSQTGWNSSTSVPSSPKLGFGDSESKCKCAENDSIQANAGDQVNEIEDDDDIIVAKIRAQNKGQQKDDDYFGENIIQRIRMVQAGSPKLASSILGGGIHGSSSPDPCLRGTTCESCVGIKTKANNCVWEVTSSGQLCVQKYVPSQEISDVAFTRDGPSIPTTTTPTPAKSYRGMVNPISHVSTTEKSIVQQLYCNEQTTCESCLSLRVQPRCVWNRDDGTCSTRTYFSTNMGGYNIKPEDCERIWNATTTTPIPTSPEPTHFETPTESNASTTTIYISEIFSMSHMDEKDELDYFGEHIVGRIRKIQESSPRLASAIRYEIQKVLFDKEEMLKQNARRFMLWRSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N240</accession>
    <name>A0A1D2N240_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000287">
        <property type="protein sequence ID" value="ODM99328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N240"/>
    <dbReference type="STRING" id="48709.A0A1D2N240"/>
    <dbReference type="OMA" id="GYPYEKY"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000021">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="9">
        <location>
            <begin position="56"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="422" mass="48091" checksum="E076E15D1F7E576E" modified="2016-11-30" version="1">MCYLVQVSCRLLALNHPDNNFILSSESDESVDVDNFQDVLATHEETHNPDEDLTTPELLTKYGYPAETHEVITQDGYVLTLHRIPHGRANPIAQKRRPPILLHHGLLCSSVDWIMNTVDKALGYRLADLGYDVWLANSRGTTYSRNHVSLTPDQHQFWDFSFHEVGYYDLPAYFDYILATTGEEKLHYVGHSQGTVVFWIAMSEHPEYNDKVHAMFGMGPVAFLNGTVSPIRYLADVSTQLQVREAEALFGDREFLPNNGVLKHLNRLVCENKYLESLICENIMFLLCGFDKPQMNETTLPVVLAHTPAGTSSHTVIHFAQLMKSGKFRQFDYGKRKNVQKYGSEQPPEYDLAKVTAKVALYYGENDWLAVPKDVLELSRALPNVMVTFKVKLEAFNHLDFLYAIDINKLLYDDLIKLLITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2L4</accession>
    <name>A0A1D2N2L4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin carboxyl-terminal hydrolase 48</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07156</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000273">
        <property type="protein sequence ID" value="ODM99523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2L4"/>
    <dbReference type="STRING" id="48709.A0A1D2N2L4"/>
    <dbReference type="OMA" id="STANEYP"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01795">
        <property type="entry name" value="Ubl_USP48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044743">
        <property type="entry name" value="Ubl_USP48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUSP" evidence="4">
        <location>
            <begin position="218"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="404"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="502" mass="57234" checksum="28421EED876D0C5D" modified="2016-11-30" version="1" fragment="single">ANVWYENYQGGPRLKSEDLCETCVQMQCKKLRALAQLDDDSKQLSELVKKCDSECAPYLKVGQDIPNSVLATKVWISKESLRNWKKIAKRAIDGPSQVALDKADQNKENEVQQVSSEEGNGDIGSFNADLFCEHGNMSPDPSTRRLIPKEAWAIIEKYFSNSVMLVATDSMSCDDCRNLEQQNTIEVQRSKEIAAKQRSALGDLYCNRNRPDIDKVGELYIVSTNFVQEWKRFIKDPSRHRPVVNINNRTLICEHEKFMYPMMFVSEFLKCNEEADEMVLLITPEEWLFMEENFECDQEIKVNVLNLDKKDNLEYRPDICNTCAESWLEGAFRRQFQYQDAPIYVIRREKGETFESEDEDAPKTTNIVSGKREVKPVNPDAWMQGFAGSNSVRRSQRPRNAKGEKTYKVSATTTIKELKSKICTDFKTLLSDQHLYYGSNELDNLSKKLQDYDIPAGAKLYLEIDTAENGSMDEPMSTVETGFQGTLLQGGSAFGDTRSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2W5</accession>
    <name>A0A1D2N2W5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000270">
        <property type="protein sequence ID" value="ODM99571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2W5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11599" checksum="95136053384907AB" modified="2016-11-30" version="1">MARENKRGCYARLTDVDDDIGVLCTSCLIRVPLNVWDDESSLVARYVHSICSILDRCGRQMIWAKVRLRRKATTVWKIERCDATKSGGAELLVTQGFSYIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4E8</accession>
    <name>A0A1D2N4E8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ankyrin repeat domain-containing protein 13C-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_06528</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000230">
        <property type="protein sequence ID" value="ODN00143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4E8"/>
    <dbReference type="STRING" id="48709.A0A1D2N4E8"/>
    <dbReference type="OMA" id="YPMHQSV"/>
    <dbReference type="OrthoDB" id="1585644at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021832">
        <property type="entry name" value="ANKRD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055285">
        <property type="entry name" value="ANKRD13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12447">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12447:SF25">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11904">
        <property type="entry name" value="ANKRD13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Ankyrin repeat" evidence="10">
        <location>
            <begin position="197"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN00143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="492" mass="56008" checksum="5FCFBA0DCC13768B" modified="2016-11-30" version="1">MDNEEEQEFFSGSEDEGDEINGDHPNSKSVASATEAGDVNNEDAVDNTKAFPLHKAAFEDNRNELETLLDQGLDIAQKDVHGNTALHIALMLGHSECANQLLNRNAPVKARNLNGWSSLAEGVSYGNRHMITALLSKSREQLKQQMSSRRPHLIKALERIQDFYMELKWDFQSWVPLVSRILPSDICKIHKKGSSIRLDTTLVDFNDMKWERGDISFLFRGNLTNRKIRNNNNGNSLVVMDNAAKAYQLMSHRTTMPDSDEEVNLLMSTDIIVAQLVTKDVEFTRSQSGWIFREDKRETVGQFHADVYGVQGINLETKKRREHLTEEDLAKNKEPVLETLTKTNPESRFCDEMEDLVIRPSLPKPPKPKATWEEYIRAVPGSPPHLGRPLNSKVSSKAFKATLAMSEDFPMTVEMLLNILEVVTPFKHLKKLREFVTMKLPPGFPVKIEIPILPTITAKITFQEFAFRDDLKEELFEIPPDYEECLNRFAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4M8</accession>
    <name>A0A1D2N4M8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitoferrin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_06500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000227">
        <property type="protein sequence ID" value="ODN00181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4M8"/>
    <dbReference type="STRING" id="48709.A0A1D2N4M8"/>
    <dbReference type="OMA" id="WRPMRGM"/>
    <dbReference type="OrthoDB" id="43906at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048250">
        <property type="term" value="P:iron import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000127">
        <property type="entry name" value="MC family mitochondrial carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000027">
        <property type="entry name" value="mitoferrin-2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF20">
        <property type="entry name" value="MITOFERRIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="19"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="116"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="207"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN00181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="329" mass="36877" checksum="60A92DBDE72509F3" modified="2016-11-30" version="1">MLRKPGDPDYDEYETLPSSSITTHMTAGAIAGIMEHCVMYPLDSVKTRMQSLIPTPGVEYRTVMNTLTHMVRSEGVFRPVRGMSAVIIGAGPAHALYFASYEHVKHVMVGKVPASYNHFVYGFAGCLATVFHDGVMTPADVVKQRMQMYASPYKSCWDCIRKTYRAEGAIAFYRSYTTQLSMNIPFQSLHFVVYESMQNITNKEKTYNPKAHMVSGAMAGALASAVTTPLDVCKTLLNTQETTTLKTLGKPQITGMMYAIRTVYQIGGFRGYFQGMSARVLYQMPSTAICWSVYEFFKFFITKRESEAESPNHLDDSNSVISRNQSKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4Z3</accession>
    <name>A0A1D2N4Z3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Epidermal retinol dehydrogenase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06338</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000213">
        <property type="protein sequence ID" value="ODN00338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4Z3"/>
    <dbReference type="STRING" id="48709.A0A1D2N4Z3"/>
    <dbReference type="OMA" id="ANEIMTX"/>
    <dbReference type="OrthoDB" id="10253736at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000202">
        <property type="entry name" value="Short-chain dehydrogenase/reductase family 16C member 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF748">
        <property type="entry name" value="FI23927P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="455" mass="49150" checksum="F7E1264402DAA2BF" modified="2016-11-30" version="1">MSNTTAQIPCIYDGLQPGNEVQAAAVSGGKNPEDVIQPADGILPLHQQPFKGAVVNHNNNTISVHSSNNAASPNQHRRSVSVTANCYLQMLTSPLKTYRERKAEAAAPTLVDESGTVAEPQEKSNFQKDMETALELMGAIAYAVYGITVALFVSIIPRRFRYKDITDQVVLVTGAGSGIGRLMAKKLALNHGAVIVAWDINKTGNEETVQQIRAAGGKCYGYQVDVSSRESIYATAEKVKAEVGKVEILINNAGIVSGKKLLDTPDAMIEKTFDVNILSNFWTLKAFLPAMMKDGRGHIVTIASTAGLIGVNKLVDYCSSKYAAIGLSEAVQSELRAEGYDKIYLTCVCPYYINTGMFDGVRSKVVSILKPEAVVNDIVAGILTNQEQIVMPRSLYPLLVLKMMVPGEVGRRIAAALGITGTMLSFKGRTHGPPPTLVNPIKSLDKARHRNNLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N506</accession>
    <name>A0A1D2N506_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoporin Nup37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000212">
        <property type="protein sequence ID" value="ODN00359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N506"/>
    <dbReference type="OMA" id="HISFHRS"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037626">
        <property type="entry name" value="NUP37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22806:SF0">
        <property type="entry name" value="NUCLEOPORIN NUP37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22806">
        <property type="entry name" value="NUCLEOPORIN NUP37 P37 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="48375" checksum="A406F88EAB280D1E" modified="2016-11-30" version="1">MPSKDIQMQSPSGPSSYYQHQDPNMSQMVRGRLGHAPSMMPGGGGFYSSADMSSPSPFQMSSMSMVDSSTPTTTGGMPRGLLKDLNNYLPVHKIKLDGDPRRLYTVENNVTRETIVVLTCTNKISLFIMKIKDDVDPSNRAERFEFMKFHELSLQPHDLEGFTISQNCSITLIPFNLTYALSTRGGKVVYVYDQGNSNEVPTALSLEEQSESLPFAVAGSYIVQIPHDYPVTHLAIDAEKGHLACIQELGTVIVWDISSQMKMAVFHIPHQGIHISFHRSEPYQLMIIDCKGWARFFNIFRQCCFRSINLVQTTVFSADWSLSNSNIFAAGFAESFTVIDSSKVLTSMNKCYEVPEMIINAIRINPLDDKVFATLSRLTGTIQLWRDHFKTHIWKHRNAYVNDIAWIHGYPYLLALGHQTLYIYEASIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N564</accession>
    <name>A0A1D2N564_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CMP-sialic acid transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000211">
        <property type="protein sequence ID" value="ODN00371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N564"/>
    <dbReference type="STRING" id="48709.A0A1D2N564"/>
    <dbReference type="OMA" id="CLYCREN"/>
    <dbReference type="OrthoDB" id="419167at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="400" mass="44867" checksum="45B2E5A0FA90D8D9" modified="2016-11-30" version="1">MGSSSMSLSQSQTKWSDLFPTRWSPVIFVLYMALFINQGILVTASQNKNHKGYTYNTVLAVLLTEFIKLIVSVGLFIERNSLSIFIAEIRQNSRVFFLYFIPAGLYCLYNNLAYVNLVTFDPTTYFLLLQFRVVVTGVVFQVLFEKRLSRHQWVSLMFLTVGCMIKEIKFDGLFGVEDSDEALAQGGSVNLNDIKKAQDAVSKPEKWVLFENPVGVVLILLQVLCSSGAGVYNEYLLKRPVASHQKQTPILIQNVCLYIDSIICNLSILAFQGKLKSVLEYDTLGIIIYTPIILAVVLNNAAIGIVTSFFLAQLNSILKTFASALELMFTAVLCWMIFGIPIHINTVLAIFIVTWAIFLYSKEPVVNSANTNALAPSVNTKRRSRDAEDLQKMLDDELDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5B0</accession>
    <name>A0A1D2N5B0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Venom carboxylesterase-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000206">
        <property type="protein sequence ID" value="ODN00458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5B0"/>
    <dbReference type="STRING" id="48709.A0A1D2N5B0"/>
    <dbReference type="OMA" id="FTHRIQF"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="118"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="271"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="646" mass="73344" checksum="73D9708AB8A9BF1D" modified="2016-11-30" version="1">MTVQPLEKPPSAKSDNERKALTGKLQQCTTPSKLHVERPASASAPENLFSSYVNVDIGALMDIKTLFNLVYSSYNRFSSSAVVKKLRRNMSWSQAIFFAFMAFILYYNDSLSQRIEGPLVKTKLGYVQGIASLSRKGRLFYEFLGIPYAKPPVGDLRFEPPQPPEPWKGIRDGSVYGTKCVQVDLLLGLIGGDEDCLTVNVFTPVKSKSKSKKDLLNVIVYIHGGFFHNGGSPFWRPNYWMDEDVVFVSLNYRLNSLGFLNTGMGSGPRRSAGGSAAHLLQYSKMSEGLFNGIISESGSSFHFWAVNREPRKQALRFLNQLGCPSDNKTAMIQCLKSANAYDIAEIHREVLDPLREAITIYKPSIEVPIDDGNTFISEHPKDLALRGDYIKVPWIFGVNSEEGLITSAVILANKTMADKAKTDWPFFLERALWFNATNEIAAEKIRLFYFGATSNETSVTENPFEALDNYTTMISDRGFNKDAHHGARIQSKHSPVFMYYYTYRGEWSAVNYFKEVRGAWPRLVEVAWAIAAAWVRKNILGQPLTNYGASHSDELALMFHMPWVSDVTQECNDYPMSEDLIKLWVDFGRRKKPLLFRNVEWEAVKPWENTVRYLNIDSEPSMIDEPFTERVKFWDDLEEGNYLVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5J3</accession>
    <name>A0A1D2N5J3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000201">
        <property type="protein sequence ID" value="ODN00524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5J3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="35371" checksum="7D2824CE86B56101" modified="2016-11-30" version="1">MDKGDGSKKRSPAGTSRRAYSLFGGIINLAHTPTTKSIATSSNVSTGTTEDPQGPSNVYTVIVNNDHTRDCTTNQKKSDQSPSTVSSLNSRMSGNGGGTGKSAGRIGPAPRTVSILTALNELAISDEIGPTPNSSSLSPPVSSTGSRNASSSASTSKSNPTCHHLSKRSGHAPSSAQENIDVSQYEIPTNTGGSSSASVHHSHSNIYHSTSSKGGIYSNPTSSASTSRFKGYNEQQQRSAVRASTNTLPSALRMAHKSLGNRKETLTLRAAAKQRDRSKSRTPDWIWKIFQLTKHGKLEELVNIYLFTHLFMFLSQLKLLFSHLSHQITVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5V3</accession>
    <name>A0A1D2N5V3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_06029</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000194">
        <property type="protein sequence ID" value="ODN00653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5V3"/>
    <dbReference type="OMA" id="FNTHSID"/>
    <dbReference type="OrthoDB" id="6481667at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51225">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="7">
        <location>
            <begin position="25"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="232" mass="25506" checksum="7BA3E6EA3D7192AB" modified="2016-11-30" version="1">MSHTVTVTRTTTTSTTQAVLLNVGYLKTLPGVLKLIHVILGIVTVSLLGHYIAYHKNHYIYRTGANYIHVADHAIFIPELFFLLIATTCLITSTLLLVSCLISIATATIIPKTVLEIIYHIVAAVLLVISSIIYLVNIEQELKNQRVVQSSYSGRLAAAELTLFSPVTFMLLVGSLHYLRCVIEKNAFWGSEGGAPSELSFGPKIFTAVVGLVNSIFYGIAVFFAYRHYRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5V8</accession>
    <name>A0A1D2N5V8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_06082</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000197">
        <property type="protein sequence ID" value="ODN00611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5V8"/>
    <dbReference type="STRING" id="48709.A0A1D2N5V8"/>
    <dbReference type="OMA" id="MRNPYKV"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000004">
        <property type="entry name" value="Glycoprotein 3-alpha-L-fucosyltransferase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031481">
        <property type="entry name" value="Glyco_tran_10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17039">
        <property type="entry name" value="Glyco_tran_10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="76"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="224"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN00611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="383" mass="44347" checksum="475DA098007A38DE" modified="2016-11-30" version="1">MAFTSPNRSLLRRFMITSALTVFIVFVWYNSSQDGRDQQGISWNIAQFSDSFPQELQAVAPLSTTVNNFINEFSSQTKKILIWNSYWKSKALWHKIFAELVNKQCPQNNCQLTIDHAELNSSDAVIFHLVDVSTEKYNFPETRDPNQIWIAMTYEPPFILQYTGVDFKKLNGVFNRTMSYRTDGDIVVRHGTFSKITPNTILPSYTSNWINSRESISERNYAAGKRRLVAWFASSRNCKSQSLREVYVKELQNYIQVDVYGSCGPYKCGVQKTMRNPYKVEEDDCYMLVSVGYKFVLAFENSLCEDYVTEKLYNHLKLNVVPVVFGASNYSLFAPPNSVIDASQYTPEELAKYLQLLDKNDTLYNEYFEWKKDYIVEAHDGCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5Z0</accession>
    <name>A0A1D2N5Z0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein max</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myc-associated factor X</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_06043</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000195">
        <property type="protein sequence ID" value="ODN00642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5Z0"/>
    <dbReference type="STRING" id="48709.A0A1D2N5Z0"/>
    <dbReference type="OMA" id="HHNMLER"/>
    <dbReference type="OrthoDB" id="8964853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11406">
        <property type="entry name" value="bHLHzip_Max"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000023">
        <property type="entry name" value="MAX isoform 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328:SF3">
        <property type="entry name" value="PROTEIN MAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328">
        <property type="entry name" value="PROTEIN MAX MYC-ASSOCIATED FACTOR X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="13">
        <location>
            <begin position="50"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="148"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="104"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN00642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="203" mass="22418" checksum="5514DF01F1341B23" modified="2016-11-30" version="1">MMSDDDRDIDMGSEDDDGVDTDDGFNEKTSQSSTSSTPTPPTTKPMTQAEKRAHHNMLERKRRDHIKDSFISLRDSVPSLHGEKVSKRPNSSRAQILKKAAEYIQFMRRKNSAHQHDIEDLKRQNQILENQIRALERAKLAGGLRAATSGAVGNPMDIKLKTRTSESDSDMDGTKSGTPTIVSVSSGGTVKRVKVVTVANTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6I0</accession>
    <name>A0A1D2N6I0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IgA FC receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000185">
        <property type="protein sequence ID" value="ODN00832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6I0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905115" evidence="2">
        <location>
            <begin position="17"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="189" mass="20054" checksum="5D7F5DB03EFF6FA9" modified="2016-11-30" version="1">MKAILLVVVFVAVASARPQFGLSNLVPLPSVLPSGPSFMTIFKTVSTVHSALSNSPLKPFLPSAMDMAMGAYRAYQTANDIQEGFKKANDYVNSMVKKALDASKIPVDQIMSHLPDSISEFLPQAPKPITDSLPSLPSMPSLPSMPSMPSMPSMPSVPSLPSMPSMPSMPSVPSLPSMPSMPSMPSFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N816</accession>
    <name>A0A1D2N816_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Dynein axonemal heavy chain 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Axonemal beta dynein heavy chain 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Ciliary dynein heavy chain 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="35" type="ORF">Ocin01_05251</name>
    </gene>
    <organism evidence="35 36">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="35 36" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="35">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">As part of the axonemal inner dynein arm complex plays a central role in ciliary beat. Expressed in sperm flagellum, it is required for sperm motility. Dyneins are microtubule-based molecular motors possessing ATPase activities that can convert the chemical energy of ATP into relative sliding between adjacent microtubule doublets to generate ciliary bending.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Part of the axonemal inner dynein arm complex that consists of at least two heavy chains and a number of intermediate and light chains. Interacts with DNAI4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="35">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000152">
        <property type="protein sequence ID" value="ODN01420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N816"/>
    <dbReference type="OMA" id="ILKNDMQ"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097729">
        <property type="term" value="C:9+2 motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000153">
        <property type="entry name" value="Dynein axonemal heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000008">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000007">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000006">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000008">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.130:FF:000003">
        <property type="entry name" value="Dynein, axonemal, heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000005">
        <property type="entry name" value="Dynein, axonemal, heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056759">
        <property type="entry name" value="DYH2-5-8_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF68">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25007">
        <property type="entry name" value="DYH2-5-8_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="11 21" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="36" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Dynein heavy chain tail" evidence="24">
        <location>
            <begin position="391"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein axonemal heavy chain 2/5/8 coiled-coil" evidence="34">
        <location>
            <begin position="1256"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain linker" evidence="25">
        <location>
            <begin position="1444"/>
            <end position="1849"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="26">
        <location>
            <begin position="1988"/>
            <end position="2309"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="30">
        <location>
            <begin position="2468"/>
            <end position="2580"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein 2 heavy chain 1 cytoplasmic ATPase lid" evidence="33">
        <location>
            <begin position="2781"/>
            <end position="2871"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="28">
        <location>
            <begin position="2942"/>
            <end position="3207"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="27">
        <location>
            <begin position="3240"/>
            <end position="3516"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="29">
        <location>
            <begin position="3543"/>
            <end position="3755"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="23">
        <location>
            <begin position="4002"/>
            <end position="4117"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="31">
        <location>
            <begin position="4149"/>
            <end position="4288"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="32">
        <location>
            <begin position="4295"/>
            <end position="4594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="201"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="21">
        <location>
            <begin position="3236"/>
            <end position="3270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="21">
        <location>
            <begin position="3398"/>
            <end position="3481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="22">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00053635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00064223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00071813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00082099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF08385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="31">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="32">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="33">
        <source>
            <dbReference type="Pfam" id="PF22597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="34">
        <source>
            <dbReference type="Pfam" id="PF25007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="35">
        <source>
            <dbReference type="EMBL" id="ODN01420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="36">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="4598" mass="528927" checksum="71A368483A739273" modified="2016-11-30" version="1">[encoded data, 4598 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N884</accession>
    <name>A0A1D2N884_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000150">
        <property type="protein sequence ID" value="ODN01468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N884"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="164" mass="19027" checksum="76123F27D2B454B0" modified="2016-11-30" version="1">MSSSINNVASQLEVYFGTSDLLEILGIKNKEAYMNAPSDPFTARQSYLRSVLRHHPDANCVSANKAEQYQEYVLRSKKMVILRDIYEFLSSENEEVKVQRNNYFEKGEHPQLLSLEILHDAAKCKKRFGVPDFERVADELKEIFAIQMRRIKELQEQEALLSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8I5</accession>
    <name>A0A1D2N8I5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TBC1 domain family member 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000147">
        <property type="protein sequence ID" value="ODN01562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8I5"/>
    <dbReference type="STRING" id="48709.A0A1D2N8I5"/>
    <dbReference type="OMA" id="NETAMYF"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="401" mass="44483" checksum="3D33AC8289F688FC" modified="2016-11-30" version="1">MSLKVKFTHLNAHAMPPIPSLTSSYSKVCAIRRSSTALNAMDIRQRRYSNKKIKGNSTNLSLDENSLSSLSTSSAASIRSHRKPFYSLDESTEIISSSEFLSTSPFEILSPEMSENMPKPKMIKNLKEFWMIGRPKSFSSAADISPSTSTSFRTSTASSTYESIKHAYDADLNGQVFLDDSGSRSDEGTTPTEQCSLADSTKTYQCSSSVPNMPFVTSVRNLIRSENTISNRDSELSTSTESASKISGERMTSNSVNPASSSSSAIDNSRETSELNFNYRNNLNRCDVEGVSQGGESEHDSGHCLSESFENSVEPEFQTGATRQPSKMPNPETLGGGNPFLMFLCLTLLLQHRDHIMKNRMDYNETAMYFDKMIRKHNVSKVLAHARQMYSNYLKQNVSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N973</accession>
    <name>A0A1D2N973_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylamidoglycolate lyase</fullName>
            <ecNumber evidence="1">4.3.2.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_04867</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds one Zn(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.5" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N973"/>
    <dbReference type="STRING" id="48709.A0A1D2N973"/>
    <dbReference type="OMA" id="NWPTDQH"/>
    <dbReference type="OrthoDB" id="10018185at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004598">
        <property type="term" value="F:peptidylamidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14958">
        <property type="entry name" value="NHL_PAL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000720">
        <property type="entry name" value="PHM/PAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680:SF36">
        <property type="entry name" value="PEPTIDYL-ALPHA-HYDROXYGLYCINE ALPHA-AMIDATING LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00790">
        <property type="entry name" value="PAMONOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905246" description="peptidylamidoglycolate lyase" evidence="13">
        <location>
            <begin position="32"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="11">
        <location>
            <begin position="145"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="11">
        <location>
            <begin position="194"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>C-terminal Xaa-(2S)-2-hydroxyglycine residue</name>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>C-terminal Xaa-(2S)-2-hydroxyglycine residue</name>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>C-terminal Xaa-(2S)-2-hydroxyglycine residue</name>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600720-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600720-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600720-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN01798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="418" mass="45424" checksum="61C5D940DF672C67" modified="2016-11-30" version="1">MGYVRGNECLAMVASVASCLIFFLAVATSQATTSPVTSHQPSHVPSTSSNNQAEENVRALLKRRFDEKIAETSSHPVEVEGWPIEEYDLGQISGVDVDKSGNPVVFHRGTVIWDFGSFNETNHYLREDEGPIDEDTIVVLDSKSGQLLASWGGGIFYMPHGITIDHENNIWLTDVAMHQVFKFLPGAEKPSLTLGQAFTPGTSTSHLCKPTDVAVSSTGTIFVADGYCNSRIMKFDKDGKFLAKFGDEGWIWMEGKGSALAIPHSLALIEEEDVLCIADREHRRILCINAGLTNPQQFGEIVSVTNGFYIGRIFGIAYSPDGRLYGVNGAGSSPAETQGLTIDWKTSQVFDTWTSKRSFISPHDIAVARDGQTIFISEIGPNRLTKFVLRPTQSTSSSGNGGGSSSSSSSFTNDLYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA42</accession>
    <name>A0A1D2NA42_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Caffeoyl-CoA O-methyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04554</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000124">
        <property type="protein sequence ID" value="ODN02123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA42"/>
    <dbReference type="STRING" id="48709.A0A1D2NA42"/>
    <dbReference type="OrthoDB" id="7774383at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050362">
        <property type="entry name" value="Cation-dep_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509:SF14">
        <property type="entry name" value="CAFFEOYL-COA O-METHYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509">
        <property type="entry name" value="O-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="22418" checksum="74D2F284BE191E3C" modified="2016-11-30" version="1" fragment="single">MAYGFGHSAEIVSNMLLEIRRLNKDEKLHGLISECCDIANGQMKYIDDCGFPETELQAKIAKDTESDEQTALRLVMLSGATEAGTNLESKIRIMMGPAMESLVQLKEEGKKFDFVFIDADKQGYLNYYKYIMDNNLLGANGAIACDNALWYAKTYNQSDTNGKALHEFIEFVKKDERVYQILLPIRDGILLIKRKVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA55</accession>
    <name>A0A1D2NA55_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pupal cuticle protein Edg-84A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04724</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000132">
        <property type="protein sequence ID" value="ODN01965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA55"/>
    <dbReference type="STRING" id="48709.A0A1D2NA55"/>
    <dbReference type="OrthoDB" id="416622at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF95">
        <property type="entry name" value="CUTICULAR PROTEIN 76BD, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="463" mass="50272" checksum="414CEDAB19A49EED" modified="2016-11-30" version="1">MKWRIRNIDKMTSLQTFLRIFSILGLFQLSTFIVTVNCLPNGVPGLAAVIPPPQVLLPPHREEGQPLDEIYLLGTGPKRTVPSLHRAANINVVQTFRPPPAPPSTAKTPSSAEEITIPQFPKHRNHRKQYTKADLIAAANSLRPAGFDFNKVLFVTPQRLASASAAASSGNPAGGINNGSKLVSVKETSDASLVPLYEHVMFPLPLFDTPVFNELKPLMEMLMKEAGAKFAKFGAPGDSNKKVLVILPKSMLTTASGSSLNRNQQPIKQTRTAPIKAQLRNHSQAQSFQKSSTPSQIKREQQVAPKFIIVPKGTKLATTSKPKPPPPSSVTTTKRVLKSVKSSHTPVKKTEKGSDLQVAATSNKFSHRSGTGGNLRLGGGSSSSVDSEKRSYSISKGGDKYSFSYAVKNDEFKDVKSHSESRDGNMVAGEYSMLEPDGYTRVVRYTVDSDQGFKASVKRIPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAU1</accession>
    <name>A0A1D2NAU1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bcl-2-related ovarian killer protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Bcl-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAU1"/>
    <dbReference type="STRING" id="48709.A0A1D2NAU1"/>
    <dbReference type="OMA" id="MGEWILT"/>
    <dbReference type="OrthoDB" id="6021377at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.437.10">
        <property type="entry name" value="Blc2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036834">
        <property type="entry name" value="Bcl-2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046371">
        <property type="entry name" value="Bcl-2_BH1-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002475">
        <property type="entry name" value="Bcl2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00452">
        <property type="entry name" value="Bcl-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56854">
        <property type="entry name" value="Bcl-2 inhibitors of programmed cell death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50062">
        <property type="entry name" value="BCL2_FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bcl-2 Bcl-2 homology region 1-3" evidence="4">
        <location>
            <begin position="138"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="31338" checksum="77246E4DD89A9D05" modified="2016-11-30" version="1">MTTLEPERPAGGQSANSLEVPQQAPRHRRPSWARPMTPQTRRIFREEDEEWSTPVAKILQLYYDHESWQQAQEILEGPGPHCRKIGDEARSIAARHIIDRLKEKNMLNKIHKVAPRLRSAVELLSKPDADYVYPHFQYVVNEMRDKYPDVYTSVTINVKIQIPDMKPSHMLVSLAKSTIEDQFGEIRMSWGKFVALLGLCGALAVDSVEAGYPDGVAEIVETFGVITEQAMGEWILTPRPYGGGGWEGFIMLNVYKAKIPPVPRTLFIIFIFIPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB11</accession>
    <name>A0A1D2NB11_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATPase family AAA domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_04245</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
            <location evidence="2">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB11"/>
    <dbReference type="STRING" id="48709.A0A1D2NB11"/>
    <dbReference type="OMA" id="HKSITGG"/>
    <dbReference type="OrthoDB" id="199596at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19512">
        <property type="entry name" value="RecA-like_ATAD3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000470">
        <property type="entry name" value="ATPase family, AAA domain containing 3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021911">
        <property type="entry name" value="ATAD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075:SF0">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075">
        <property type="entry name" value="PUTATIVE ATP-ASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12037">
        <property type="entry name" value="ATAD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="348"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="587" mass="65894" checksum="262F115899880203" modified="2016-11-30" version="1">MSWLFGIKSNPPAPDLSFGDLAPPPQGGAAGGGGGGGKEPPKDGKIGKESTYRFDSAALERAAEAAKNLERSPHAKEALDLAKLQEATKQKEMETEMAKFGAISEQAKLDAIRVAAEERQKILQEEAKLNKQKALYEDELARRRYADQLEQQRRAQEDTLKRQEESVQKQEQIRQQTIAKEMQMREHERKNRIKEEAEVKAKVERENRDIYLEQLRVKAQESRVTTLESIKTIGSVVGTGLTAFVSDWDKMVQAAGAMTLLALGVYTAKNTTHLAARRLEAILGRPSLVRETSRVSPLELVQHPIQTFKKLARKTEEPLKGVVLHPKLEERLRDVAIATKNTRTNKGCYRNVMFYGPPGTGKTLFAKRLAAHSGMDYALLSGGDVAPLGRDGVTAIHKVFDWANASRRGLVLFLDEADAFLRKRSAEKMSEEMRTALNAFLYRTGEQSRKIMIVLASNTPEQLDFAVNDRVDEMVHFALPGKEERERLVRLYFDEFILQLVDKRTSRLKLAEFDYSKTCSEISQVCEGMSGREIAKLASSWQASGFASEDGILTKEMMVERAQDAAKQHRQKTEWLTDSERAKVMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBP8</accession>
    <name>A0A1D2NBP8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">THO complex subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBP8"/>
    <dbReference type="STRING" id="48709.A0A1D2NBP8"/>
    <dbReference type="OrthoDB" id="205166at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008501">
        <property type="entry name" value="THOC7/Mft1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05615">
        <property type="entry name" value="THOC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="198"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="224"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="295" mass="32941" checksum="20456A50995961A4" modified="2016-11-30" version="1">MANSSDNALTVETKFFLITEEIIKRRLLIDGDGMGDERKLNTLIKSYISFLDGEDTEENDLANLRRIQTQVRQMELVVRRTDASITANLDAKEIYTELKDKVQTEITETQEKIVTSKASLEEATKHRKYSMEYDALAKLIESKPDRKATELKRMGLELELDTLQRRESKLDQQLEYRKRTASMMGSTIERLKDLMEYQESQQGGSAAKSPKASSSRNGGISMDVDSTSQSEPPSPMDQNQSSLDGINGTTSVEKVIIQPQPSSLPAPGNGNGAPTEKSKSEKYEDLSESEGDENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCE0</accession>
    <name>A0A1D2NCE0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Catalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03928</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCE0"/>
    <dbReference type="STRING" id="48709.A0A1D2NCE0"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905355" evidence="8">
        <location>
            <begin position="23"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase core" evidence="9">
        <location>
            <begin position="70"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN02755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="538" mass="60248" checksum="94DD1BD35D4297FB" modified="2016-11-30" version="1">MDSRKLHWSIFITIFCFGRGLGYNPVNTGHVNLPVPGVSTIPSMSPSDPATLQISNWASQNTISIAGTVRDEHGCPVPSLTASLGIGTRGNLLLQDVILIDEIGAFNRHGAFGYFRVTHDISTLTKADFLNEVGKTTRVLIRVSTAGSISGSSDMEREGRGFAIKFYTADGNFDLAGTTGVTFPIRDPMLFTDLSRSRGRNPQTFAKDITMRWDFSTHRPEGILYLLKVFSDFGANSRVIDMYGVHAFKFVNRNGIPVFVKFHVLSQQPFRWWNDTELATVSGSDPDHATRDLYDAIANQNFPKWTLKIQVMTAEQALKYPVNPFDATKVWRQEEFPLIPVGEIVLNENPVNVFNDIEQAAFSPARMVPGIEPSPDRLLIGRMFAYGDAQRYRLGVNYAQLAVNRPIMQQVKNYVRDGFMRENPNGGGSPNYFPNSFHGPTPNQTATENVFHVNGVVDRIDTGDDVEDNFRLARLYLYKDLTVVQRRRVAQNLGNSLAKAIKEIREKAARELFFRITPEFGKQVWDDMQAAVTANNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCX6</accession>
    <name>A0A1D2NCX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch-like protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCX6"/>
    <dbReference type="OrthoDB" id="684045at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="189"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="354" mass="40669" checksum="6647F9CD73F4FC48" modified="2016-11-30" version="1">MSLFLLNKKRIPRYHLTQFDARKYCSSLKVEILPFDIDVLNNVAEPGAKQPKLLNLIQSLLGKTGNDNIEINMVLTKVDNETAQMEAFVCGLILGQVERGFKNASLGMKLVIGIYDKGVQIHNFDYGAEQISAGGYWKFDQRLEATIARKLEECSYYEASVTLQLVPVTTNLSPEFANNKQMLENKFSCDTGITCQNGVIAPCHKYILATNSRFFRQLFHSNQRAGTVDDLNLRAECVDAMLKFLYYRDVDDFEENPNLAMELLTVANEKRFLTLKDYLTKFLMEQSSQRFNVEQGVQLFTETQGWVVTKVFRKRQWKNLEELKNSREFKTLLENNYEMGMQLVMCMATQRSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND10</accession>
    <name>A0A1D2ND10_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein 49</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND10"/>
    <dbReference type="STRING" id="48709.A0A1D2ND10"/>
    <dbReference type="OMA" id="DCEVWIL"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="91"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="246" mass="27779" checksum="7438F9EAD52F2675" modified="2016-11-30" version="1">MPGSLVFQGADQYVIDCIKDIDTVNTNTFEERCATLRFLLSQQPQLIEARNEYQFTPLHYACAIEFRNGRQLEFIRCLIAHNADLNARGVYGLTPLHIAVCSWKAHSNVFEVICTLIKHGADPDAVTEHGSTLLHIAAHQLPSMVFHELVEFLVSIGRTKSFNAKDSDGWTVLHHTVSERHFQPRVETLEIFKAHGFDFNAITNKGISIALTAFSSGCSKNFLKILRQFGTDCEVWILDPEQKNFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFB5</accession>
    <name>A0A1D2NFB5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
            <ecNumber evidence="3">3.1.3.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Inositol polyphosphate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_02693</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83420"/>
            <dbReference type="ChEBI" id="CHEBI:83423"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:43561"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43552"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83416"/>
            <dbReference type="ChEBI" id="CHEBI:83419"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:43553"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57627"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:77144"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77155"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57895"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77156"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:20630"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:10685"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:25017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="EC" id="3.1.3.67"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:25018"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PTEN phosphatase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EC" id="3.1.3.67" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFB5"/>
    <dbReference type="STRING" id="48709.A0A1D2NFB5"/>
    <dbReference type="OrthoDB" id="16692at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043491">
        <property type="term" value="P:phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051896">
        <property type="term" value="P:regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14509">
        <property type="entry name" value="PTP_PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000029">
        <property type="entry name" value="Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057023">
        <property type="entry name" value="PTP-SAK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045101">
        <property type="entry name" value="PTP_PTEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF81">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10409">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22784">
        <property type="entry name" value="PTP-SAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="22">
        <location>
            <begin position="18"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="21">
        <location>
            <begin position="104"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="C2 tensin-type" evidence="23">
        <location>
            <begin position="235"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="333"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="455"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00051341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODN03960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="591" mass="65753" checksum="AD0FE4530559D4F7" modified="2016-11-30" version="1">MPKSMTTHIKKIVSKKRRRFQQDGYDLDLTYILDNLIAMGYPGDKLEGMYRNNIEDVSKFLESKHNAHYKIYNLCEERTYNANKFKTGIVVKYPFVDHNPPQMGSIPALCQDVHEWLSRDPKNVAAVHCKAGKGRTGLMICCYLLHSRQCQTAKDALEYYATKRTHDRKGVTIPSQQRYVGYYEYLLRTSSEAGQSNNDKTGRTSDRAFKSNPSTYPHLSRNHIYVLSVRMEKLFRKKVFDRLNLLFFHGLSSNQPVCLENSNNSMISTTSSSVYCGYSPNHLNIELEDGLMLSGDVKLEIFSRPVKILKKYKLCHCWFNTFFVDLESPLQQQQHAPPAPHPHHHHHNIQTQHQQQQAYRNGCNNGGAVGVGSFSGGAEEMSACVGLGVVSSSNHSSSNNGSCNNQMRKSDQDIAATAIGSTQASCSGGGPSSKRDSLGYDNCCSVKVKFTKIEPEKLRTHRSSKPIDRTMSCPPPSDTVRPRLPAEWATYSKDPPLKPPDDDDPPLALTNSPKQHYTMIFSKDGLDKAHKDKGCKTFSGDFAVHLLLSDPSPTSGYSDYSSASSHVSRSSYGGGGSSSCSASSSGVVGWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHD6</accession>
    <name>A0A1D2NHD6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Microsomal glutathione S-transferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02187</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHD6"/>
    <dbReference type="STRING" id="48709.A0A1D2NHD6"/>
    <dbReference type="OrthoDB" id="410651at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="18796" checksum="3DBDF0DB69ABFD06" modified="2016-11-30" version="1">MATTTDVPLAGPPPVGSEVKSLASLVKKSFSSSGLGTPLIIPKGYGCVVLTGIGSVVLLKWKSMKVSEARRDFIVPNPITHSDSCMNFNCTYRAMQSTLEIYPQFLFLLMIGGLELPYLSTVGGFIWIVGRYAYAKGYYSGDPRKRANGGFYIIGQCLLLIGAIKFALKRMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHU7</accession>
    <name>A0A1D2NHU7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHU7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="160" mass="17473" checksum="8F43880D2B27FB99" modified="2016-11-30" version="1" fragment="single">ICGAEDSPSNPLPKEFINHAIGQDDKILPVDKNQIVDLLIHKLKADPKAPANATDELKAAASKFLNGTKLDRLVRAVESLNLTQDHVQTIASEMSSAATPEHADKVRRAVEDAFVFGKPPPFQRGPPFPGPPRFGGTGLPQNPFFTTPLCKRHYSIFLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIC5</accession>
    <name>A0A1D2NIC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipase member H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN05024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIC5"/>
    <dbReference type="STRING" id="48709.A0A1D2NIC5"/>
    <dbReference type="OMA" id="DNERIDP"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF173">
        <property type="entry name" value="LIPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00821">
        <property type="entry name" value="TAGLIPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905601" evidence="5">
        <location>
            <begin position="21"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="6">
        <location>
            <begin position="88"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="36333" checksum="CDC6B99515843108" modified="2016-11-30" version="1">MKSQFFIICCVAVAFGVVSSVPFRERELFWYPTDKGTVVPAFLKGGPASTQAVEDDVEFWHYLAGEKNGRLVEPDCQGCTAAFVRGAPLVVLAHGFGSDHVGGFGNNHRNGFETRGEPVNLVFVNWSKLAQAPWYETAANNVKPVGEYSAKLINFLVAQGVATLDNTFFVGHSLGSHVANYVTLNTVGGKIRGVFALDPALPLFGVKEDNERIDPEDGQFVNVIHTSMGTLLDGGLAFTEPRGHVDFYPNSGKDQPGCPGFDFGACSHSRSYGYLGESIGRPSAFPACKCDNWEDYDAGRCTCLDQAPMGWDTPRTTRGVYYLRTNANSPYGQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIN7</accession>
    <name>A0A1D2NIN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_01815</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIN7"/>
    <dbReference type="STRING" id="48709.A0A1D2NIN7"/>
    <dbReference type="OMA" id="FCATDAN"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001480">
        <property type="entry name" value="Si:cabz01071911.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="671"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="699"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="727"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="755"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="783"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="165"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="324"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="486"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="638"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="867"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="873"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN04826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="900" mass="95683" checksum="4EE389C6E000A08D" modified="2016-11-30" version="1">MDIEGSVYASAELLSSLRYPMSTSPNSPCSSALLLSSPWPISPTSSSLSSSPQSSLTTINDNTLLSLSSCSPTSLSSCSPPLSVPIDTSSELGLACTTPTAVIFSTSRSSSSSTAARVSSSPSTTALTLVDPVSSPGEHAAMEVAHAPGKSILCVHEQDHGDVIHFSTSDGQLNHVNGNGNGNTRRSAESGAAGTSSSNTNLSSVMEAALAADKDLQSSTTLELQNTLHTQHNNNNNTILSSPSSSSSHNTDGNLFPTLILTSAPSSSSGATGDVIPMRLYASLTSVPSSTATVINANGNASSSILTNGDNNANLSSTTCILMTPHHHHHQGGGGDDDDLHQLVTSSSHHHHHHHHLHHSGLLNDDENNNSGASTGFTFGGFGGGNDHDISTNEEEENKHSSSSLMNGATLGTILMEGCCYDGGKSHNDLTLTKLTSSVDCDFSSSHGKLKDILMNGNSHHQSLLSSSSTNGDNYLLRDLEASYNNNNNRNGGSGNNDLINVQGHPRGQSDEGSFVIPKEDELEELKLHSGEQSSFNEAINSIYHSSGSHHHHSGGAFCATDANGDLIMVTTTDAAHELDSVYSSGVITSSIGSSSVSIAPLSSSTVLSWSTQDDNNGGLQGHNLDDSLLMKSEDGNFGLDDEELLDPKEEREDDEEDGDMLDGSGGKGELKCKFCGFVCCSKSSLGIHERRHTGERPFACKYCGRLFNSAQCCKHHERLHTGDKPFQCSYCGKKYAVSTRLKRHERVHTREEPYKCTECNKTFRWFDAFRDHRNTHTGVPLYLCSVCGKTFTSYLKFYYHERGHLMKKERDRDRLIKQRQSNGGNIGIVKVAKPVPSNTIDIIKSLQQNSSACAISSSSLSSLSGGGVVGMNGNKKQQGGVSNKGKKSKANSKKGIPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIX4</accession>
    <name>A0A1D2NIX4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Tyramine beta-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_01551</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIX4"/>
    <dbReference type="STRING" id="48709.A0A1D2NIX4"/>
    <dbReference type="OMA" id="THYQEIR"/>
    <dbReference type="OrthoDB" id="129121at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042420">
        <property type="term" value="P:dopamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.310:FF:000004">
        <property type="entry name" value="DBH-like monooxygenase protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.230:FF:000001">
        <property type="entry name" value="Monooxygenase, DBH-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020611">
        <property type="entry name" value="Cu2_ascorb_mOase_CS-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028460">
        <property type="entry name" value="Tbh/DBH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF29">
        <property type="entry name" value="DOPAMINE BETA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00767">
        <property type="entry name" value="DBMONOXGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00084">
        <property type="entry name" value="CU2_MONOOXYGENASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905623" evidence="13">
        <location>
            <begin position="18"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="14">
        <location>
            <begin position="25"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN05179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="605" mass="68617" checksum="9C0A958328E50797" modified="2016-11-30" version="1">MLRLIFRFALLWAVADAIFNVRLGEDITLYWELDYAAGEFVAEIHAKNVDPTTGWVGVGFSSRGNISDGSGDFCITWRDQLGAAASASSAGEHEPPMQITDVNIRNGTNIIEVDQQQDCLDFQFVFQNGTLKWTFRRKFTTCDYFDYALEEGTTHLHWVKGTGPLYDIKGVSIKKALDQGFKRIRFLKNIESPEQKQTRINNLRDGSTWNFKILNTQVKVPPVETTYWCQIFKIPEGVAKKKHHVIQFGSFIQKGSEDLVHHMEVFHCSADAHVSIPMYAGPCDASPPELSVCSRVIGAWAMGAEPLSYPAEAGLAIGGPEFNPYVRLEMHYNNPGLKGGYVDSSGMEFWVTNKLRTHDAGVIELGLEYSDKMAIPPKQKRFQLTGVCNRECTSVSFPRDGITIFASQLHTHLTGARVLTRHFRPSLHPGNVDGFVELPFMNWDNHYSTHYQEIRRLKRPTRVLPGDVLLTTCEFNTLDRTNITLGGFAISEEMCVNYFHYYPRTKLEVCKSSVAWKSLREYFHFMAEMEGQHIEPEGAVSSNYNGIEWTPFRAKLLSDFYNKSPIDMQCNQSDGTRFPGSWDSMSVPKFPKLLQARNPNDECYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ50</accession>
    <name>A0A1D2NJ50_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="18">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_01407</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="18">Membrane</location>
            <topology evidence="18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="18"/>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ50"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ50"/>
    <dbReference type="OMA" id="YRMYVKG"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051480">
        <property type="term" value="P:regulation of cytosolic calcium ion concentration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000001">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000002">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000033">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000001">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000147">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000007">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022141">
        <property type="entry name" value="ATP_Ca_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12424">
        <property type="entry name" value="ATP_Ca_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 18" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 18" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16 18" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="17 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 18" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="390"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="843"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="915"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="949"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="988"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1020"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="31"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="273"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1121"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1121"/>
            <end position="1134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODN05290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1213" mass="134338" checksum="D071AEAA375ED1C1" modified="2016-11-30" version="1">MAEEYPSQFGISLFELRELMEVRGQEGLEKVQENGGIQEICRKLNSSPITGLGGSKSELDVRRQVFGANVIPPKPPKTFLMLMWEAIQDVTLIILQVAALVSLILWLVTKYSSSDDHGSEEEDEEHGWIDSVAILVSVVVVVLVTAFNDYTKERQFRGLQSRIEGEHNFSVIRGGEVLQIPVSEIVVGDICQIKYGDLLPADGILIQSNDLKIDESSLTGESDHVKKSEVSDPMVLSGTHVMEGSGKMVVTAVGINSQSGIIFALLGAAAEEEAKPKEKKKDKEARIAMKKADEERGMGGGRQVISNSHAAVRDGRPPPIPEEPEPVREKVDKNQDKSVLQAKLTKLAIQIGYAGTAIAVLTVVVMFVRFSITTYGIKKEVFHVKHARSFVNFIITGITVLVVAVPEGLPLAVTLSLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSHICGVQYKYSPKHTELPPQVAELICHSISVNSAYTSRTLPPENPGELPKQVGNKTECALLGFIQNIGKDYMEIRERITEESFTRVYTFNSERKSMSTVIPRPGGGFRLFTKGASEMIMKKCGYMFGKDGKLERFTKEMQDRLVSEVIEPMACDGLRTISVAYRDFVPHKTEENEVQVDGEPNWDDENNIVKELTCLCVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARSIAYKCGIVKPGDEFLILEGKEFNQRIRDANGVVQQYLIDKVWPRLRVLARSSPQDKYTLVKGIIDSKVSENREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVLWGRNVYDSIAKFLQFQLTVNVVAVIVAFTGACVVSMSPLKAVQMLWVNLIMDTLASLALATELPTPDLLLRKPYGRTKPLISRTMMKNILGQAIYQLTVIFCLLFIGAGIMDIDEGTMMVEPSAHMTMIFNTFVMMTLFNEINARKIHGQRNVFKGIFTNPIFYVIWVLTAGSQVVIVQYGGLAFSTAPLSVEQWMWCLVFGVGALIWGQVVTTVPTRKLPKLLSWGRGHPEQFTEGVTIGEDYDPDADKRRSAGQILWIRGLTRLQTQLRVIRAFKSTLEDMEEKRSVHSLHSLHSLRSSRSHPGLRPMSDISYIDEDPTKTPSPAEGQKSGGNQFRGTMGREDHRNVRWTNSEIRPATQSSLSPHRHISRTLIQELPKLVHETSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK03</accession>
    <name>A0A1D2NK03_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK03"/>
    <dbReference type="OrthoDB" id="8250507at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="449" mass="51212" checksum="1EFECD220C8478CD" modified="2016-11-30" version="1">MCDCFPQVGGGVPVPDRCKQTTGNSEYGENFKQWGNPVLSQNFIPQSPGSPDNVWKQRYSFSKGPRFGVPPYCDCTPPVERSNHLIITFSTIPDLASNRRTIVTLMIASSMIRRPEEIVWSMESDLNLALFFRSNSYVKTKRMPELLICPGSLGNVCGEVMQDPCGGPCVQPCSDEGCQNPCGIEIRYSNKKIRPPQPKLLKENLIKPGTDTSDCCGCPRPIPCCPCPEDDKVCDACCGCEYPCKLHQAATIPMRKYPISWNTPRYVPDPRVPPRRPRLLCAGGTLECPVQNQFPTQQAIKQAKYRLMDKLEKERCRYPPAWHHINFLRLLTFQNIAHETTRQVNEKARKAQAEYDDKGFPPKCMPYYCLEGGRPKDPRPPFDHFSTYEADYIWDYNTRFKLLGGEIPCQFEVKPLCCDVRNACEFIKERTEEKERWGEDWECCPPPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK35</accession>
    <name>A0A1D2NK35_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_01124</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK35"/>
    <dbReference type="STRING" id="48709.A0A1D2NK35"/>
    <dbReference type="OMA" id="GHERDTI"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN05582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="391" mass="45398" checksum="5769C4F00C2EB8A3" modified="2016-11-30" version="1">MKILRLIHIGLGLLEGKDWQEMRRFTLKCLRDMGFGKRSMEGMMHEQVCEVRKYLKKNVNKTLYLKPILELAVINSLWAVMTSEKYDIEDPAKRQVMMILTEGIAEQNILGIAAFLPWLAKLAPDYTGYSKGLKFLGAPEGLFREVIRKHVETYVPGRERDFIDVTLTRIYSTTDPKSVFYGDVGMRNLHYTLLDLFFAGSDTLSSTLGWSFLYLAVDPKIQDKVQEEIDEIIGKTRLPTLEDRPKMPYCEATMAEVLRKSSFVPLGLMHTALENTEFKGYFLPKRTVLLFNLYEIHHNKDYWKDPENFRPERFITEEGTFRKDDHVMPFFTGKRSCPGEQLAMNEYFLFFTGILQKYRFALNPVAPKPYLGPRSGFILCPPKHELLVTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKJ6</accession>
    <name>A0A1D2NKJ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative nuclease HARBI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_00869</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HARBI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000016">
        <property type="protein sequence ID" value="ODN05798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKJ6"/>
    <dbReference type="STRING" id="48709.A0A1D2NKJ6"/>
    <dbReference type="OMA" id="QVIHASC"/>
    <dbReference type="OrthoDB" id="7788538at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045249">
        <property type="entry name" value="HARBI1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930:SF85">
        <property type="entry name" value="GH03217P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="8">
        <location>
            <begin position="38"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN05798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="233" mass="27048" checksum="5C769F301E5D7880" modified="2016-11-30" version="1">MKAILAKEKEWIFWPNCDERKRIRYFMSDKLPGCIGYIDGSHITLDEAPVDDPESYFNRKQNYAIQLQAVCDNDKRIRNLTVGYPGSVHDARVFANSSIATSHNYFDEGEWIAGDSAYANTKFLVTPFKSNTAGVDDQRRKQFNRYFSGFRVNIECCFGSLKEIFQSLKGLRVRVDKKNGHRLACNWITACCVLYNMILPSLEFDLSRYEYDESVESTENHSELEHEQQRSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKX6</accession>
    <name>A0A1D2NKX6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Homeobox protein Hox-A7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00816</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Antp homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000014">
        <property type="protein sequence ID" value="ODN05869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKX6"/>
    <dbReference type="STRING" id="48709.A0A1D2NKX6"/>
    <dbReference type="OMA" id="TEFAVDK"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009952">
        <property type="term" value="P:anterior/posterior pattern specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050296">
        <property type="entry name" value="Antp_homeobox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000047">
        <property type="entry name" value="HTH_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45659:SF4">
        <property type="entry name" value="HOMEOBOX PROTEIN ABDOMINAL-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45659">
        <property type="entry name" value="HOMEOBOX PROTEIN HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00031">
        <property type="entry name" value="HTHREPRESSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="9">
        <location>
            <begin position="46"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="279" mass="31960" checksum="ACCC72FCDAA6844D" modified="2016-11-30" version="1">MVSPPPPSAYETFSEDPMGSLVVRRANACGITTFIRTGDPSNINPATGKRMRQTYTRSQTLELEKEFHFNKYLTRRRRIEIANALGLTERQIKIWFQNRRMKAKKDMKIGAETTGAEGLISYPGSIGLSSPNPTVIQQNHSLLLQQQHQHQQLHQNHLHHHDHKQLQQHHQFGGQLCHIQSQENEHETDKAHHLGQVPSSQHHPFFHHFTGYPSPSEQQGTSNINSADVAEAEVLLESEKHQFKTSNLAEDYLKEETEFAVDKITAKFLDHSDDETKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL36</accession>
    <name>A0A1D2NL36_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Proline-, glutamic acid-and leucine-rich protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL36"/>
    <dbReference type="STRING" id="48709.A0A1D2NL36"/>
    <dbReference type="OrthoDB" id="20900at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34105:SF1">
        <property type="entry name" value="PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="34201" checksum="866F287338D767F4" modified="2016-11-30" version="1">MGSSSDISVWDLWAETAKESESLGDPVFLECLEAVTNSRIFVDLPDDKLKNSLSIINTLLNDPKTRSKGLTLLSEFLAQSNPSRLIAFQDSVVSALHLVVKGLESPLASNVLVSFIPKCHSMTEVNQSMTSSIIPKILAHFCENSQDSNTQKSVEELALLRVCLEEYHGPCGQFRDKLEKVLVPLLDSENGNLVDFLGDVMPLLSYAGGGGGGGEKHTKDWSDMLTKILKTTYSTVYTLYGSSCPLLEPENPFDGEELSGLKRITEPQVLLRMSLIKRRLHRLLVVISSYLREINIILVISECLFQLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM55</accession>
    <name>A0A1D2NM55_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Roundabout 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM55"/>
    <dbReference type="STRING" id="48709.A0A1D2NM55"/>
    <dbReference type="OMA" id="TDNKSHR"/>
    <dbReference type="OrthoDB" id="428111at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000026">
        <property type="entry name" value="roundabout homolog 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF34">
        <property type="entry name" value="MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="111" mass="12548" checksum="4B4E2B361DF31602" modified="2016-11-30" version="1">MRQYRSPRITEHPKDVLVKKNEPTTLNCKAEGKPEPIIEWYKDGELLNNSPANDGRRIFLPGGDLFFLSVSDGKKESDSGTYWCIARNQVGNVRSRNASLVVGGKVYDFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM81</accession>
    <name>A0A1D2NM81_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_00284</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM81"/>
    <dbReference type="STRING" id="48709.A0A1D2NM81"/>
    <dbReference type="OMA" id="FVIESTM"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="19" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODN06380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="476" mass="54543" checksum="E1EC6A9363464956" modified="2016-11-30" version="1">MSEPEPDLNKRASLTDEEVESTLRRRKGEGDGQSNEGEDGEGGKSAESADSDDEKLPEEKYLEKLAKEIPQGTDKTPEVLSGALQGLSDRWRNWVIRGFFTWLMLGLFGIIIYLGPLALMVTTLVVQVKCFAEIINIGYSVYRVHNLPWFRSLSWYFLIASNYFFYGESMVDYFGVFVNRTEPLRWLITYHRFISFSMYILGFVWFVLSLVKKYYMRQFSLFAWTHVSLLIVVTQSYLMIQNIFEGMIWFIVPVSMIVCNDVMAYMFGFFFGRTPLIQLSPKKTWEGFIGGGFSTVVWGILVSHVLCQYPYFVCPVEYSETIDKMTLGLECEPSYLFQPQEYTLPAFMITVCQIFGLRSTITCYPFCLHSLAMSMFSSVIGPFGGFFASGFKRAFKIKDFGDVIPGHGGFLDRFDCQILMATFVNVYITSFIRTASPQKLLQQVLTLKPEQQLELYNSLRDSLMHRGILQVVHGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMH5</accession>
    <name>A0A1D2NMH5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Voltage-dependent calcium channel type A subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMH5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="26356" checksum="D23A19F3B5EA87F4" modified="2016-11-30" version="1">MIATVMTVVWKHFAYDAEISLNKMFRCGNILMKYVHIDICNLLFCGYYVQQYYIFLLSCSLIDGKIYFGVIELQDMVTDGKDGNASPLLDDKMNPDSQRRRYNEFDRESMQDMDMMREEDEYGRESDTMYLQPHHHAARGRRLRSRSPSPGRGGRYSEHEIGFSEVADDVVELVRDGTGGKRGRERGPRRKFRGEEFSLSPRFPAGYHDSALSPSTPEQGANNGFLPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMY2</accession>
    <name>A0A1D2NMY2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Myotilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMY2"/>
    <dbReference type="STRING" id="48709.A0A1D2NMY2"/>
    <dbReference type="OMA" id="TNDERFT"/>
    <dbReference type="OrthoDB" id="10031887at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF45">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 12, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="73"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="20276" checksum="1E28CB0257037043" modified="2016-11-30" version="1" fragment="single">VSWIRRRDFHILTSGRTVYTNDDRFQIQHSEGSDEWTLIIRYVQTRDGGTYDCNVASGRGIIAHFFNLNILVPQAFILGAKEYHVQQGTVISLVCIIENSPRQTAQYLYWYHNNQMVNYGSGISVHTEPGIHTHSRLTIPLAGPQHAENINNLLVSIGNYTCKAANTQPATVQVYVSDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0K4</accession>
    <name>A0A1D2M0K4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Long-chain fatty acid transport protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_20187</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008637">
        <property type="protein sequence ID" value="ODM75170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0K4"/>
    <dbReference type="STRING" id="48709.A0A1D2M0K4"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM75170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="442" mass="50535" checksum="43E5B455EEF34BFB" modified="2016-11-30" version="1" fragment="single">LLYVLYYKILFQWIKRKRRNETIARCLDNIVAECEGDRICFYFGDEKWTYKQIQALSFRVQIIFKKLVSKRGFSWTGHDKSARNGCHLDRIRKDRGNFSAHQHEPSGRFTRKVSFSSEMQGFHYRNRTERGGMFTQSWKEPTSVAKDQEPNYLDPILYLFTSGTTGIPKAVACSHGRLCFLASTASAINFSPMTLLTLLFQCIMLEACFHLCGPLFTDHLVFSTGSWSLSESVFSEGWATTRGWAAFQERFKVKTFVDIYGSTEGNCTMINLEEKLGHVATFPIWLQPSHPIQLIKIDQITGEIVRDEKTGFAIRCEDGEPGELIGKLLILCQCRDLMGTSMATTIFKIGLVTRSVGKQRMLHNHGQFDIQSLTEGMKLSLPKYAMPMFIRLISNSKGLDMTGTLKFQKFRLRDDGFNIESIEDPILIYSSSTDSYSKMDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M407</accession>
    <name>A0A1D2M407_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endocuticle structural glycoprotein SgAbd-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004806">
        <property type="protein sequence ID" value="ODM87713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M407"/>
    <dbReference type="STRING" id="48709.A0A1D2M407"/>
    <dbReference type="OrthoDB" id="6618885at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="23295" checksum="C9B88B3659CF7193" modified="2016-11-30" version="1">MKYLDRVCSLLSPSSSLVCPAAQSAQSLVRSTPLAVVRDDGYGATLLRREIPITRLSHDIRGSQSDSLEYETGNGISVVDNTQANFGRGGEYVDEYGQLVRSESLLSKSGSFRYTSPEGQLISTNWVADENGFRAEGAHLPRPVEMPAEHAEAHRLALQSLRCKQLRFPISHPYLQLRCPSSYPYFQLCCPCCPCYRTSSTSCPIWILIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4B0</accession>
    <name>A0A1D2M4B0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_18928</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01004742">
        <property type="protein sequence ID" value="ODM87752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4B0"/>
    <dbReference type="STRING" id="48709.A0A1D2M4B0"/>
    <dbReference type="OMA" id="PHATHIF"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="38"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="15983" checksum="6B823C87632A2B56" modified="2016-11-30" version="1">MESSSLNPYSLLSYTPRYFSLLSTRSQLPVWEYKPKFMELLSKHQCLVLVGETGSGKTTQIPQWCVEYASFSGGVSGVACTQPRRVAAMSVAQRVSEEMDVALGSQVGYSIRFEDCSSSATILKYMTDGMLLREGMTDLLSPPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Y1</accession>
    <name>A0A1D2M4Y1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposable element P transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004197">
        <property type="protein sequence ID" value="ODM88040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Y1"/>
    <dbReference type="STRING" id="48709.A0A1D2M4Y1"/>
    <dbReference type="OMA" id="QCEKIDA"/>
    <dbReference type="OrthoDB" id="8190203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048366">
        <property type="entry name" value="TNP-like_GBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21788">
        <property type="entry name" value="TNP-like_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposable element P transposase-like GTP-binding insertion" evidence="1">
        <location>
            <begin position="47"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="112" mass="12688" checksum="1BD63E6CA771C8B1" modified="2016-11-30" version="1" fragment="single">LACDGATTNKSAWKFLGISGENGNVINKIVNPVDESRNVYFFSDIPHIIKCVRNHLHKQGEAKFSGKRVSWGFYRALYDTDKTRDLRLAPKLTYLHINPGPFQKMVVSHAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Z2</accession>
    <name>A0A1D2M4Z2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004196">
        <property type="protein sequence ID" value="ODM88045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Z2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01670">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="221" mass="24652" checksum="492C06C789822431" modified="2016-11-30" version="1">MNTGTTHTGNNYENLVIGENPCTIEAVCETLSNCHSAATLWSKLIDVARNLGVPGDRLVMISISLTLGNKASSAVLHEILQEWQSRETTNAKLHILATILEETLLKDCADVLRLRFSNGHEDNLNKNVCQAQSDQNQNEIASGAHATTYYIDDTFGGSRTQLIPGEAYLYEDNATTRRIMKLKNIFLRIAPAIYFFLMCVSFLIWVLVVFVSENPNEIKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M639</accession>
    <name>A0A1D2M639_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Copper type II ascorbate-dependent monooxygenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_18300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003664">
        <property type="protein sequence ID" value="ODM88382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M639"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016715">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase C-terminal" evidence="3">
        <location>
            <begin position="30"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM88382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="353" mass="39749" checksum="EE27ED98D1FC3842" modified="2016-11-30" version="1">MFIGQLTHTSASFIVPPSSLGHAILGQCAAGWCVYETTNRNGSAIVGGYPTRSEMCLVAIYYYNRVPGYGDCRSETRTERYAKFIGIRNTTFDSIRREAVITEPEIYSSLSVETFANDVIDWDLGTRAELQRLHLYQPQISTCRNYIPRDITRTATNRARVARQAIYEPTPLTLAAVPFTPTPRAFVPTSNPFVPPPKNWKPMYTPKPWVRKPKLKQKVEKVINGLQGILDNFLEKTADKNLGGFKRQKNYSPIYTPSPPLYTPLHPIYTRSTPIFISSTTTTSTTTTSTTSTTTSTTTTSTTTTTTPPPPTTVAPPPLTEFEEDNIEHVSVLPRDIPRYQRPSDCKRKRWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M643</accession>
    <name>A0A1D2M643_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003605">
        <property type="protein sequence ID" value="ODM88438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M643"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37629" checksum="81B7C623CCB46FD6" modified="2016-11-30" version="1" fragment="single">MAKVFERFGLSWHDVFIVVALLETSWWIMYAFIDGADIILRMAILSSNVVYHTYLVVQKCVSVVKLGMAFWCIWYGTVCKGRSFPLRVYVMVGLFMDVAMILSWGVIAVDEEWPLSPSNAYGLHYILTFGVIRALVHEGDFVCPFGSSVISTVNGAVVGIPDRSVNSADNLVFFGKGISGVVQYYGFEVQRAAVVSLVWDFLWTLSIIVTQELPEFLFDVIFIGIFGSLPLFIPTENFLMRACRLVVSGLGVVAVLKKTGVRFWVVASSLLVLGNIGFLCYVMSNSVADDSALSLFVICCVFFASNGARVLVLYFVLRVCVEAPVRDQDQGFVNHVYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6J7</accession>
    <name>A0A1D2M6J7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">5-hydroxytryptamine receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_18140</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003445">
        <property type="protein sequence ID" value="ODM88542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6J7"/>
    <dbReference type="STRING" id="48709.A0A1D2M6J7"/>
    <dbReference type="OrthoDB" id="5951059at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004993">
        <property type="term" value="F:G protein-coupled serotonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071880">
        <property type="term" value="P:adenylate cyclase-activating adrenergic receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF199">
        <property type="entry name" value="IP13425P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="122"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM88542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="394" mass="43601" checksum="016E2E250E67469D" modified="2016-11-30" version="1" fragment="single">MASFYVPLCVMVVVYVKILRVVADKKKQMGWKPAHPHQSIHRSSSITTNHSSSFGGGGLVVSGSPRGGCGPPPLHALEEQLVHYVNNNGWKYLGCTNPPAPARGSPAAPTSLLASNVSVDASNVNNNKKDSTGSQNAAATTPLLKSGRRGSNTSVKNNYRQQKQKGSRKSSHNSLKEHHNHSHQNGANGSAVTYFFSSTTIHRIKKEKLFGGLKEHKASTVLGIIMSAFVICWLPFFVLALVRPFLNINGIEIPPWMGTLFNWLGYANSALNPVIYATLNRDFRKPFREILCLRCSTLDDMMRREFYHQQYGDDHDRENYLRRLSRPHTENEVSYATEGPTNQRGGVTSVVFVLSTVPSIGAQLFDLLSISGFDLALALQLHLWQMERALFSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7I1</accession>
    <name>A0A1D2M7I1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_17745</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01003050">
        <property type="protein sequence ID" value="ODM88937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7I1"/>
    <dbReference type="STRING" id="48709.A0A1D2M7I1"/>
    <dbReference type="OMA" id="RTHVELC"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000117">
        <property type="entry name" value="Probable E3 ubiquitin-protein ligase makorin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF10">
        <property type="entry name" value="IP09428P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="MAKORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="187"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="12">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="377" mass="43102" checksum="33ACE7AFD80AB1E0" modified="2016-11-30" version="1">MEMENSNRRSSRNVFGGDFKSKSRSRSKEKINSSIKSSPTVRPQSTFKPPENWADAPEFVPSWLAANSDADKTKNETTTTSSTKPRSYAAVVGTAHATEGNANNVTANNGAKLNYWEEWCPFHVLGECRYGEQCVMIHGVKCDYCGEFRLHPTDVLQRDKHIKECIEEHEKDMELSFAVARSLDKTCGICYENVMAKEPASEQRFGILPSCNHCFCLSCLRRWRQARQFENKIIRACPECRVTSDFVCPSRYWVENKEDKDKLIGCYKIALGQKPCRYYRNGEGQCPFGNKCFYLHALPTGQIVDVGPPRRIIGAEGRVPGSGQNTSLWDYMEDWELQWMDIEEIMEILELGDGTVSELLEDLDVVDDTFDYWRRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8S2</accession>
    <name>A0A1D2M8S2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17296</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002683">
        <property type="protein sequence ID" value="ODM89386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8S2"/>
    <dbReference type="STRING" id="48709.A0A1D2M8S2"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="117"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="213" mass="24717" checksum="47278F6E47589AB3" modified="2016-11-30" version="1">MKERRKLKAVKKRTVTSPSAVVEVAMESEPVIPEVSEAVDGVELEINCGECGMQFNHTDYRRATDNCGHVKCLKCLQKSNDCCATCEEKGKEDNKPKPSSLSPVGPLFKVPQRPPPHRCTHCDKRFELKWNLEVHLNDTHDIEVYHACNRCHRTFTYEVDFERHMRIHDAQLYKCSICPAAFRRKDNLQRHLINLHKMSKEDIRELAMRAPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9E4</accession>
    <name>A0A1D2M9E4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002512">
        <property type="protein sequence ID" value="ODM89595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9E4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="343" mass="39129" checksum="DCE4FC298C2162E4" modified="2016-11-30" version="1">MEQIKGDSRFGIDGICDIMVRFGGISWRTIFQASIHWRYLHYFEITQQEVDEPMSQEPVGKPNVDATPNESTSRGVPTNTLPEASACCVPKTGRKVVKAKGAKAVAGKRKSQRLASANRRRSKSKAQVDGKQWRLSKFFSEAGNPPQSLLLVKKRTRSKSLSTSANKRMKPSESQKRRKKPSGERRRKKKPSGERRRRKPVASEKRRKKSSGEREAKKKPSRTTSSQASRFRKREKKSSGELTSEKRTTKKSSVNRRRKPSVSQKRSKKKVSGQQRRTKPGVQPSAVRRSSRLAGRGIGRPRTKPKMTKREERAFHKANLQKNALEFAKKRRENAKQKKQDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9N8</accession>
    <name>A0A1D2M9N8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002511">
        <property type="protein sequence ID" value="ODM89604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9N8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903680" evidence="1">
        <location>
            <begin position="30"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="18596" checksum="B7E0D74C2DC60D65" modified="2016-11-30" version="1">MFNFSSKFAWANVLSLALVFSSLSPSVSGLSCWECDDNYEGKVDNYRRCWWDGGNGPSKPCDIPNGMCVSECVFELYTDIARDYSRQTCSNDTSIVGEPGKCGKGEKQINPELKLTLTVCSCTTDDCNRKLSCYEEHNTEIPTTAGTTPTGGGVFRFGLLGIAVLVISLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAN0</accession>
    <name>A0A1D2MAN0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002253">
        <property type="protein sequence ID" value="ODM89989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAN0"/>
    <dbReference type="STRING" id="48709.A0A1D2MAN0"/>
    <dbReference type="OrthoDB" id="8744624at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40240">
        <property type="entry name" value="PLEXUS, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40240:SF1">
        <property type="entry name" value="PLEXUS, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="258" mass="29150" checksum="56A461B93202E251" modified="2016-11-30" version="1">MGVPKLGSAIKCHTSELLSFKDMAQEVRSHPTGCTTKPHFPSLSRYSPFTRAIFRENKSTDACDSLHDQWNLSEKSKIAAPQNGMYNNIKNFICSVCGVKTYRKRIRALPFKKFPVLAKSMQPGSFTICKNRFAIVCLDCSETLWCQSEEYDRWGLPVHKRLYNWMTRTPPPDNSWEACVARLPSGKMQLPRSPPIVSSVIQNKGLGTAKELHSPASNTCLKVKQKTPTSETMCSLPTPDSDDIDKMSFTWSNIIFNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAT6</accession>
    <name>A0A1D2MAT6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002169">
        <property type="protein sequence ID" value="ODM90105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAT6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="28102" checksum="95A61DB703988D30" modified="2016-11-30" version="1">MDACVLDPEESDRLPIDYMNQKGNVLESFSTKLIRIDYLGRCIFLAPFFCNMESIHLCIENLSPSEGTIMLVTSNFRMTNVAMNKIRAAYGIKSRTVITSAFLTALRMTAERKGFKPPNYLKVGITHARGPYSERKLENRFSSLVQCLPLSELSSTSLTESEKLIEINADNEHEVDAFFYLLTLLGLLPKKLLQICRPHLVKTALTGTPSSEKMFKIQNGLLEAIIPIPPRVDGLDYICAYHNYGVMFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBU5</accession>
    <name>A0A1D2MBU5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_16207</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily. Sigma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01001946">
        <property type="protein sequence ID" value="ODM90476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBU5"/>
    <dbReference type="STRING" id="48709.A0A1D2MBU5"/>
    <dbReference type="OMA" id="PWFKEQD"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000030">
        <property type="entry name" value="Glutathione S-transferase S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000035">
        <property type="entry name" value="hematopoietic prostaglandin D synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="82"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM90476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="23950" checksum="5833A60DDBACBFFB" modified="2016-11-30" version="1">MAETYKLTYFNLRALAEPIRLIFAYAGVEYEDVRIEREQWPEQKENYPWGQLPVLQVGDKTLCQSNTIGRFLARKFNLAGEDEWESAKIDELVDALTDLRSEWRKFFMEQDETKKAELKKAFVETAVPKYFGKFEAQIASNNGGPYLVGKNLTWVDIQTAHFLEFFEVSKPGLLDSYTALKKLRETVFENDKIKAWLEKRPVTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC89</accession>
    <name>A0A1D2MC89_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NFX1-type zinc finger-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001880">
        <property type="protein sequence ID" value="ODM90617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC89"/>
    <dbReference type="STRING" id="48709.A0A1D2MC89"/>
    <dbReference type="OMA" id="PMENDIV"/>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057373">
        <property type="entry name" value="ZNFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25396">
        <property type="entry name" value="ZNFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZNFX1" evidence="4">
        <location>
            <begin position="291"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="3">
        <location>
            <begin position="488"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="3">
        <location>
            <begin position="800"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="779"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="607"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="969" mass="111472" checksum="F9B2D6976F576BED" modified="2016-11-30" version="1">MKFLEHICAPNASSSEIVTKLHDEHLTDWDNHIESLIKLKDDKLLVQTVIFLGTNLSCDNDNEKDEDENRRVCEKQVKILVCTCRKEFLELLTARVSAWSISKSKKFELGQDELGKVLVSIHSFCQAVIHKLPYLGKDLLPNLICTGIGVLAASQQLSSQHPTLLKELMGLQQRIAEINETFQSKKGVVKKDGFSEAYERLLHSKEPPQNFRNVQIIPTLEELLEDKIPFLRPNKIKGAYFSPEHYLDVQFRLLREDFVQPLRKTVEHFLENKLKYLKTKSKKKFKTQQQNGSSCIYTGVTFGRVEKSRENENVHFFKLPQETVKKVNWTKSKKLLPGCLVMFTSDCCETAIFATTLAPPFRETKTGIDPRRKELSQGVLRVSIETGVNHVVKNLNYIMFECEAYFEAYRYNLDILQKTRIFKNESRITKFIVEASSLVDIPNYAKRMKKGTRAELVLPFQVSGEPVTVPLSQTQEWPEYLIKSQLGLDDNQYQAYKRALTSELSIIQGPPGTGKTFIGLQILKTLLLNKTGRKNLPNQSLVIPNAPILILCYTNHALDQFLELLLSEIDELDLIRVGGQCKSEILKRHSLPEKRAQMKLPYIKDGKKNFYRQVQSLEKQLSDVLNEVRELENPRGILDFKSLALGLQVLEKLPCSWCKVLGSGDWLGIPEEIVEPVDPELEKMVIKEKAKLGNGNGVENVMERNETWISQKNYYFPGCSSVDCREHAKWLNGRLLNYTPMENDIVYKDMKYQIEACDSRAKLIETIFDMYKNKQLYLTNQDDEESESDNDDESESDDDEVGVELVIEIFNAKPQQDIEKWEMSVRWALYFKLVEIALKFGRKKMKQIEEDLVIPRIKLKEERQYQDGILLRQADVIGMTTTGAAKNHSMLEIAKPQIVVVEEAAEILEAHIVTSLTENCNQLILIGDHFQLRPTTNVYELEKKYHLNVSLFERMILNNINFCALKVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC94</accession>
    <name>A0A1D2MC94_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-1-antiproteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001916">
        <property type="protein sequence ID" value="ODM90531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC94"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="51" mass="5815" checksum="D58C2D7F10E79020" modified="2016-11-30" version="1">MVGLGAKGNTRDEIFRGLRFTENSEEAIAKSYHSVINGFQVFISHYSILFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCW9</accession>
    <name>A0A1D2MCW9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger and BTB domain-containing protein 41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15834</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001770">
        <property type="protein sequence ID" value="ODM90847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCW9"/>
    <dbReference type="STRING" id="48709.A0A1D2MCW9"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="228"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="368"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="502" mass="58352" checksum="1061F0C6C8282DB8" modified="2016-11-30" version="1">MPEVQVQQMKISKRTPGLSLPASSHPARQSDFQVEYIFVEREDESFPVDTHDDYDNDFPSSDPLPSPQPSNTEEALPKSFQKALDLLPTKNYHGRDLKPKKKYKKKLPDVEEPLQKRRKTVVNKSYAEVDEFKDLPPPRSWIAYIKKKKKSSEDEEDEYVPPEKTEPPSTKFKEKVKTRKITFFSCLLTKVEDSSSEETFKCSKCDAILPNRWDMLRAHVVKEHTDRLVCSECGEKFGRLAYLKAHLKKKHQNAAQPVLKTPCHVCGRPCDATYMKTHRWTHYSEEERDAALARGEKLPYRKNKKFQCDQCEKRFYSMDILKAHTKKVHEGIPLPPAKRRLCPDCGADVRNLAQHIRQKHSDYGKRKFACITCDKRFVSQNDLRQHKFQAHGNEKPYQCEVCGRGFKTRQNMEQHHTNVHVNAKVYQCPHCPMKFTNKRVWFERHIVAKHGGGDGTISQPNQRVEYEQEEQKLNVEQLQAVNLCQQDFGGGVVPMSNLHPFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCX2</accession>
    <name>A0A1D2MCX2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-erythrulose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15857</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001779">
        <property type="protein sequence ID" value="ODM90825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCX2"/>
    <dbReference type="STRING" id="48709.A0A1D2MCX2"/>
    <dbReference type="OMA" id="GHQYINH"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="9963" checksum="FD168FC5D72AFBEF" modified="2016-11-30" version="1">MWQFDVNFFACINVAQTAARKMIDGGSGGTFVNVCSLGCKGAVPFTSMYCASKAALEMLTKSMAVELGPYNIRANCIAPGLVGHQYINHLILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDX0</accession>
    <name>A0A1D2MDX0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleolar protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001654">
        <property type="protein sequence ID" value="ODM91143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDX0"/>
    <dbReference type="STRING" id="48709.A0A1D2MDX0"/>
    <dbReference type="OrthoDB" id="441771at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007276">
        <property type="entry name" value="Nop14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183">
        <property type="entry name" value="NOP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23183:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04147">
        <property type="entry name" value="Nop14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="564" mass="65480" checksum="4FDAF348917DED7F" modified="2016-11-30" version="1" fragment="single">DEIQDEELKKLQKLEKERLRRMQALDPTIPKHRSADELTDGYELTENVPILSYKEDGQLHKESDEDSSGDEEETAEAEEEEDSDEGSESDAFSDLLTDDEDQSPDKISKKSSKVRERLDDSKETKILENDDIPYVLNIPKSYEGFRKLMKKYQAIVKDGERFVVRFKIVTERLVKYSLLADKTRLPDLFVYLLRMIIENLEESPHLSENVQKILDISSAQLHTMLLSNPSKCVELYEGESYIQTFLSNKNNKLSIAKIAFYKVCSQIFCVTDFCHRVLSPIKVDMLEIIHSFSANSYMGLLKVLAIVDVIYELSKDSKRYCPEVMRLLLDVLEAVSLPIEQVKFKRRRLEFLRISPPQTKNLSWSDCKPDLSDVEEVVLDGSEVLSLLLRTFDLISQFIQIQHKTRPFFNLTYKCIKSEELVLKLDWANVDFHEVLFSKKLSSTIALPQEATVEDEVPSSMIDRPKMLRLYEPLVEENFDGSRKRKLKRKGQTQEEARLSHKVKKEMKSAVREIIKDNAFLAKQQMKEQATKDAERNRRVKELLGSLSNQEGDFRKLKKQKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEC9</accession>
    <name>A0A1D2MEC9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Programmed cell death protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001623">
        <property type="protein sequence ID" value="ODM91232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEC9"/>
    <dbReference type="STRING" id="48709.A0A1D2MEC9"/>
    <dbReference type="OrthoDB" id="10252486at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="130" mass="14282" checksum="A68EF04C2273381B" modified="2016-11-30" version="1">MDNVFGGGSGPANSPSGDAPNQPSKEEEMQQQRQRQEEFKNQVLNQILDQQARARRRGGDADQHGSNGEDRRGKINETQLIDILEKVGGGGPTMFGNSNASGSAAVNFSRRRTSLDDDDDEEYNKIMEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF21</accession>
    <name>A0A1D2MF21_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM154 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001509">
        <property type="protein sequence ID" value="ODM91543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF21"/>
    <dbReference type="STRING" id="48709.A0A1D2MF21"/>
    <dbReference type="OMA" id="FYQRPKE"/>
    <dbReference type="OrthoDB" id="311506at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036126">
        <property type="term" value="C:sperm flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033336">
        <property type="entry name" value="SAXO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516:SF16">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="20480" checksum="1C75C895C92521D3" modified="2016-11-30" version="1" fragment="single">GDFYQRPKEEAVHGERAKPIRQNDNLFPEGNFYERPEKSAPLKGDRADVIKPKDNLKSEGDFYQRPKEGIPQGEKRSPIRQGDNLFPEGDFYQRPKEEAVHGERAKPIRQHDNLRPEGDFYERPEKSAPLKGDRADVIKPKDNLKSEGDFYQRPKEGIPQGEKRSPIRQGDNLFPEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFF4</accession>
    <name>A0A1D2MFF4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001445">
        <property type="protein sequence ID" value="ODM91727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFF4"/>
    <dbReference type="OrthoDB" id="8298994at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="319" mass="35154" checksum="EFB973D42F9D1CFD" modified="2016-11-30" version="1" fragment="single">MEKLTGEIEQLSEQNIELQESMLEQKGLIEKMADGFAGLQQQLSANAERLNDFEKLTGQSATPFAFSNHTCGGELVAQSGAIMFSTRSYYAASLPSSCVWTVRANNRESIKVSTFSTLSSYAINTYVLEIVRPNGTTPSTNGSQPFQIKITKLQKNMPHIFSGPTIFIVTSLINTAVTDVYLDLHWDGLGALLSKDTFFTHETRPANLTQFNSNELTTWNSTFLEKMDANYTLDFTTIVISNFSTKSYLQAAIGYGGCSNGESFIVISQMMENGSLTTDCCKTNCEGLNSLMNFGSSYVILITKKFKAPMTFNLTWVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFN9</accession>
    <name>A0A1D2MFN9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA (Cmo5U34)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001419">
        <property type="protein sequence ID" value="ODM91789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFN9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10912" checksum="B92F01812731DBA9" modified="2016-11-30" version="1" fragment="single">MGKNCQSEVISYQLSKLYNAMSQLIFDRQFGPFPNILYRSVGLETSVVDRIGNLKERYYVGHEEQQVHHAEQEEFLKQALTNLNEFSRMKLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGD6</accession>
    <name>A0A1D2MGD6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14618</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001338">
        <property type="protein sequence ID" value="ODM92067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGD6"/>
    <dbReference type="STRING" id="48709.A0A1D2MGD6"/>
    <dbReference type="OMA" id="WITNDIC"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF67">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903974" evidence="6">
        <location>
            <begin position="19"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="174"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM92067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="471" mass="50968" checksum="0188510135C1DAAF" modified="2016-11-30" version="1">MFKKLLLITFLGVVLNEALTPSTTNQKIHVSLLETLINDGKANVVISFNEETRHILDSVNRIRFDSRGHKITFLKTQLEQLTKDSQRSVISILKSHSTTFQSFWINNRIIVKNASIELIQQIAQIADVSEIREELVIRHQPPIPTRTKQEEGGWGVVKIEADQAWNLVGGNNGYGVVVASMGTGVRYTHEAIRGNYRSSYGWFDPYTRTRNPIDVHGHGTNALGLVTGINGIGVAPGAQWISCRGCDDPGDGSITCTEAAVTSCGEWVLCPTLWNTQQPDCSQAPNIVSGSWNEGGRGNDFYADVVDAWKVANIIPIFPVGDFGTAGCFSVHSPGDYEGVIGVGATAQSDAIVPSSSRGPTLDGRIKPDVAAPALNIRTICKESDTAYCNAAGTGMAVPHVAGTVAMLLARDPELTFDQIKDLLQNNADRELGETESCGGTNSTQDWPNNVYGYGRINARRALTALINDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGR3</accession>
    <name>A0A1D2MGR3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arginine-hydroxylase NDUFAF5, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Putative methyltransferase NDUFAF5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14567</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001326">
        <property type="protein sequence ID" value="ODM92113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGR3"/>
    <dbReference type="STRING" id="48709.A0A1D2MGR3"/>
    <dbReference type="OrthoDB" id="16816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050602">
        <property type="entry name" value="Malonyl-ACP_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090:SF1">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="6">
        <location>
            <begin position="26"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00040937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM92113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="17274" checksum="5DB0DF64547C2A4E" modified="2016-11-30" version="1">MEKTAVCTTILRMKIIDIKRDINRVLDLGCGRGHILKHLNSGMVGSVVATDICQEWLDQIDAPEDVTCEKLLMDEEDIVFQPNSFDMVLSSLSLHWVINKAFSNIHRNGVFLVGCSETALIFVSKLRPVFVAVGRAGTGRPPKTKRNKKRAHSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHS7</accession>
    <name>A0A1D2MHS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001210">
        <property type="protein sequence ID" value="ODM92525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHS7"/>
    <dbReference type="OMA" id="GMQSGEM"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="266" mass="23755" checksum="B84704E08CA19C11" modified="2016-11-30" version="1">MQSGGGGFPGSVGGAGGGGPGNGGGGYPGSSGGVGGPGGGGGGFPGSSGGVGGPGNGGGGYPGSSGGVGGWRRRRWVPGSSGGVGGPGSGGGGYPGSSGGVGGPGSGGPGVTSGFGGGYQGGAGSGGNGGFAGGNSVGGGFGGGYSAGAGAGAGFSAGGGSFGGGSSGGGGGAGLNIESIQKANLVANFQQGGGPGNGRPKYGVPGVTPGQPQGRYYRSAIALASKLKSMRAIKRSDRVVSISKVVKEKPKTPIETAPTISKKKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIY8</accession>
    <name>A0A1D2MIY8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 13">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2 13">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_13725</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2 13"/>
    <dbReference type="EMBL" id="LJIJ01001108">
        <property type="protein sequence ID" value="ODM92959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIY8"/>
    <dbReference type="STRING" id="48709.A0A1D2MIY8"/>
    <dbReference type="OMA" id="YMARVFK"/>
    <dbReference type="OrthoDB" id="8249496at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032587">
        <property type="term" value="C:ruffle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046488">
        <property type="term" value="P:phosphatidylinositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010634">
        <property type="term" value="P:positive regulation of epithelial cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000011">
        <property type="entry name" value="1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056586">
        <property type="entry name" value="EF-hand_PLCG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057061">
        <property type="entry name" value="PLCG_EF-hand_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF159">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23329">
        <property type="entry name" value="EF_HAND_1_PLCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23583">
        <property type="entry name" value="EF_HAND_2_PLCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 13" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 11" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="3 12" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PH" evidence="16">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="14">
        <location>
            <begin position="486"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="14">
        <location>
            <begin position="595"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="15">
        <location>
            <begin position="722"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="PI-PLC Y-box" evidence="18">
        <location>
            <begin position="869"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="17">
        <location>
            <begin position="990"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM92959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1115" mass="129592" checksum="F85279FA26D2A0C8" modified="2016-11-30" version="1">MPMDNILYETYEVICKNSKLERLINVSLFQVKEVRPGKSSKDFERWKSDTKKIENSRCFVVYYGIDFRLNTLSVALPTKKEAEGWMKALEYLIEKRPTSYLAQLDIWFLKQYEIMVANTNQHTITLKQMKDFTNRISYKISTGKLKESFQTFQNENGDLNIFGFTKLVREFLHDEQVFTDCFGKYALGSKIDLNGFQEFLQHEQNELSFNEYISFFRDYVKAGSKGLAYMNAHEAVDFLFSKQNQVWNKKYGTVYQDMTRPMSHYWIASSHNTYLTGGQVSSESSAESYVRCIRQGCRCVELDVWDGADGSPVIYHRMLTTKVAFLDVIKAIRDHAFVTSEYPVILSIENHCSVKQQKIMAKKFDEVFGKMLVTSQLFKEETQLPSPSQLKRKIILKCKKLPKHAKEIIEYAEQNKDLDLSDTFKNGKMYVQEGSKWEPYFFALTHDQLIYTEIVDESDQTNNNDDDGSDSNSVKPIEELHYSKKWFHGKVHGGVRAAEDRVKKLGVDGGFLVRQSDTYAAEYALCFLSQDKAHHLRIKSNPEQTRYFLIPSKQFDSVYSLISYYRKNPLETKDFYIEKFTTPVPQPERHEQQPWFYPNHNFPEKMDRKKAEEVLRKIPLNGAFLVRYSSDGGANGRFVISFRVENHLKHCRVKEDGRLLVVSSNRFENIEKLVTYYATKSFYRGLKLKHPVNEELYKFAHSVEALDDKVYTSPDYLDTNTNSSTQCRAISPYHPLDPDSLTFDRGDVITNVVKHDGVWWKGDLGEQIQKTFPSNFVEEVEPADSPFGELQKGSIPVGKADVEKNTDEANPYILKVYSPSSPVPFKAAVPSYKEAKEWQELINSVYNRSTKKVSQSDLIQKKNKIAQEFSKQIIYCCTVSKLIPEDVRMKGRIFNHMTSFTELLAEKQMSIDPEFYLWYHEVFQVQFSRVYPRFNRIDSSNYNPIRSWNFGCQMVALNYQTPDRPMQLNHGKFRQNGSCGYVLKPEFMFRKNFNPGRVRDLELNEIQSLTFEITIIAARQLFRIGNKFISSPFVEVEIIGADFDCQKVRTTKYVADNGFNPFWNEKFTIKVLNPDLALIRFSVSDEDSFGDSQFVGQATYPVRLYENKTRTGEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJD9</accession>
    <name>A0A1D2MJD9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_13567</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001074">
        <property type="protein sequence ID" value="ODM93109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJD9"/>
    <dbReference type="STRING" id="48709.A0A1D2MJD9"/>
    <dbReference type="OMA" id="NYHEGER"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000508">
        <property type="entry name" value="Myeloid zinc finger 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000425">
        <property type="entry name" value="PLAG1 like zinc finger 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000690">
        <property type="entry name" value="Zinc finger protein 354C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM93109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="17729" checksum="65C4DDA6D6F37185" modified="2016-11-30" version="1">MVNQPPPPPVPVVVAIANNTGNPAAGGSGNASNNGAPPAAAAGSAAGAAAAPQKKFPCHLCRRSFMHKQSLDIHMRSHTGERPYSCADCGQSFSQRATLNRHRRRVHLPKSQQCNECGRKFGCRDYLVKHIRTHTGELPYQCPKCSKRFRDKSALNQHARSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK31</accession>
    <name>A0A1D2MK31_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Platelet-activating factor acetylhydrolase IB subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001052">
        <property type="protein sequence ID" value="ODM93174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK31"/>
    <dbReference type="STRING" id="48709.A0A1D2MK31"/>
    <dbReference type="OMA" id="IADAKCI"/>
    <dbReference type="OrthoDB" id="505607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904161" evidence="1">
        <location>
            <begin position="23"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="78"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="198" mass="22600" checksum="E135D465E99B8221" modified="2016-11-30" version="1">MKFLLAFQTLFVLGIWIVPTLAQNPWTPQIRNEQWLFFSRKLANEGRPVWEANYAPLGAINYGLGGIELSMFCGVLQTVVVVYIGSNNVPVNTVDDIVRGVNTVVDKIHEKLPNTNILLVGTFPRADQPDLSGTLRKIRDIDEKLEALVGGDTQRRGHFFDLFWFLAPSSLDRIYEHLYVGDKLHLNTDGYQVWQRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML94</accession>
    <name>A0A1D2ML94_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">Ocin01_12902</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="27">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000916">
        <property type="protein sequence ID" value="ODM93780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2ML94"/>
    <dbReference type="OMA" id="CYEVEKM"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031672">
        <property type="term" value="C:A band"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051239">
        <property type="term" value="P:regulation of multicellular organismal process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="38"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05748">
        <property type="entry name" value="Ig_Titin_like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000321">
        <property type="entry name" value="Bent, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000440">
        <property type="entry name" value="Bent, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000097">
        <property type="entry name" value="Bent, isoform F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000460">
        <property type="entry name" value="Bent, isoform J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000504">
        <property type="entry name" value="Bent, isoform J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000147">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000107">
        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000031">
        <property type="entry name" value="Myosin-binding protein C, slow type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000612">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:002083">
        <property type="entry name" value="Protein CBR-UNC-22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000160">
        <property type="entry name" value="Titin a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000034">
        <property type="entry name" value="Titin isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000003">
        <property type="entry name" value="Titin isoform E"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000127">
        <property type="entry name" value="titin isoform X1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001003">
        <property type="entry name" value="titin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000249">
        <property type="entry name" value="twitchin isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000056">
        <property type="entry name" value="twitchin isoform X4"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000006">
        <property type="entry name" value="Uncharacterized protein, isoform F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000831">
        <property type="entry name" value="Uncharacterized protein, isoform F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000567">
        <property type="entry name" value="Uncharacterized protein, isoform G"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000051">
        <property type="entry name" value="Uncharacterized protein, isoform J"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="69"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14340:SF9">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14340">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="37"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00014">
        <property type="entry name" value="FNTYPEIII"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="39"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="30"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="39"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0106">Calcium</keyword>
    <keyword evidence="17" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="19" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="275"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="388"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="666"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="765"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="867"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="965"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="1061"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="1160"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="1258"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="1361"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="1556"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="1657"/>
            <end position="1750"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="1755"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="1852"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="1953"/>
            <end position="2048"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="2052"/>
            <end position="2141"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="2149"/>
            <end position="2242"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="2248"/>
            <end position="2343"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="2342"/>
            <end position="2435"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="2443"/>
            <end position="2536"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="2542"/>
            <end position="2637"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="2738"/>
            <end position="2831"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="2837"/>
            <end position="2931"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="2935"/>
            <end position="3022"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="3031"/>
            <end position="3125"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="3131"/>
            <end position="3226"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="3230"/>
            <end position="3319"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="3327"/>
            <end position="3414"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="3420"/>
            <end position="3514"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="3518"/>
            <end position="3607"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="3615"/>
            <end position="3710"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="3716"/>
            <end position="3811"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="3815"/>
            <end position="3904"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="3911"/>
            <end position="4005"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4011"/>
            <end position="4105"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="4109"/>
            <end position="4198"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4205"/>
            <end position="4299"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4305"/>
            <end position="4400"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4499"/>
            <end position="4597"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4603"/>
            <end position="4698"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="4702"/>
            <end position="4793"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4800"/>
            <end position="4895"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4896"/>
            <end position="4990"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="4996"/>
            <end position="5091"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="5192"/>
            <end position="5286"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="5292"/>
            <end position="5387"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="5391"/>
            <end position="5480"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="5489"/>
            <end position="5583"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="5589"/>
            <end position="5684"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="5690"/>
            <end position="5785"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="5791"/>
            <end position="5867"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="5976"/>
            <end position="6064"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="6065"/>
            <end position="6161"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="6166"/>
            <end position="6254"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="6259"/>
            <end position="6352"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="26">
        <location>
            <begin position="6357"/>
            <end position="6450"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="24">
        <location>
            <begin position="6507"/>
            <end position="6762"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="6830"/>
            <end position="6918"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="6955"/>
            <end position="7038"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="7156"/>
            <end position="7241"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="7260"/>
            <end position="7349"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="25">
        <location>
            <begin position="7360"/>
            <end position="7443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1036"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1633"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="2230"/>
            <end position="2257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="2519"/>
            <end position="2550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="4300"/>
            <end position="4327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="4384"/>
            <end position="4407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="4740"/>
            <end position="4766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="5267"/>
            <end position="5294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="23">
        <location>
            <begin position="2243"/>
            <end position="2252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="4313"/>
            <end position="4327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="4744"/>
            <end position="4766"/>
        </location>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="6536"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="ODM93780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="7456" mass="825868" checksum="430D6621D80477A0" modified="2016-11-30" version="1">[encoded data, 7456 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLF1</accession>
    <name>A0A1D2MLF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000907">
        <property type="protein sequence ID" value="ODM93817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLF1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904215" evidence="1">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="143" mass="15795" checksum="AAF7A2BDDB3EBBEE" modified="2016-11-30" version="1">MQILISMFLVACSATLLVVGLPTGEYPVESDSYAIAPKLDQSDESAFLELTEMVPPSADAGPHIYYMNQDGIAEPAGRSMKVLVKREVAPASHNDESMLTDETVIIGPPSGNRPFGTPAIHLGYRPAHAYYARRYHKYPWNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLM7</accession>
    <name>A0A1D2MLM7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase TRIM33</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000918">
        <property type="protein sequence ID" value="ODM93775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLM7"/>
    <dbReference type="STRING" id="48709.A0A1D2MLM7"/>
    <dbReference type="OMA" id="ALACKFT"/>
    <dbReference type="OrthoDB" id="1870062at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043563">
        <property type="entry name" value="Sp110/Sp140/Sp140L-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46386">
        <property type="entry name" value="NUCLEAR BODY PROTEIN SP140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46386:SF1">
        <property type="entry name" value="NUCLEAR BODY PROTEIN SP140-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="213"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="418" mass="46978" checksum="E25444DA26E7736B" modified="2016-11-30" version="1" fragment="single">NPEQISTTAVDETALESGSDNDGPNGTTADFSSPSNEGKADDQELGLGKRTRRPKYFPDHVSPEDTLRVYKPAKNSGGGVKRGGTTGLTPTTSIKMPRLVPEGLIDPVSTDPVSIDPVLIDPVDIKKEKVNETEEETGEVEEPVIPGSSKELTEVSPVCPQKRGRGRPRKIKTLDLESFESATESSIEEPADNIEYPIQGNAQMKITDYDDSEDYCKICFDGGQEIIVCCDTCPNVFHVNCHVPLIKVIPGEDEPFYCFNCTSKQMIDERLAALPPVEGSEDQVLEESNEHHFALACKFTMECHLIPEIPTVRWIFPRLYHVVVGKDKVPFHLKYIRERLTLGQPAPFPNLRTFVLSFRQMFIQAFIYYQNYEHAKEHLPVIHTCFQKFLALLEEYYPSFRKDFDDVVISAGSFNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM11</accession>
    <name>A0A1D2MM11_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras-GEF domain-containing family member 1C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12592</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000863">
        <property type="protein sequence ID" value="ODM94090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM11"/>
    <dbReference type="STRING" id="48709.A0A1D2MM11"/>
    <dbReference type="OMA" id="PNGHIDF"/>
    <dbReference type="OrthoDB" id="20825at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF356">
        <property type="entry name" value="FI05912P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="21049" checksum="EC202431D4E01321" modified="2016-11-30" version="1">MGVISFLVNLKEESVSWSKPLYAELSEVEKAVDPQQNYAPYRKLYKAAVWQSNSSVAAAGGDSQTYRILVPYFSLLMKDIYNLDSVHPSRLPNGHIDFEKCRQLAKLVTEITSWQKVSCDFVQIQSIFNSVQASPIFNEQELIYASYLCEQPETPREKEQFKKLHRQNFQVPLIACNSSSENDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM35</accession>
    <name>A0A1D2MM35_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Gonadotropin-releasing hormone II receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12619</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000866">
        <property type="protein sequence ID" value="ODM94063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM35"/>
    <dbReference type="STRING" id="48709.A0A1D2MM35"/>
    <dbReference type="OMA" id="WFANENE"/>
    <dbReference type="OrthoDB" id="6435638at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032870">
        <property type="term" value="P:cellular response to hormone stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241:SF59">
        <property type="entry name" value="ADIPOKINETIC HORMONE RECEPTOR, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241">
        <property type="entry name" value="NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 8 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="65"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="296" mass="33499" checksum="D0F3E66541972C8B" modified="2016-11-30" version="1">MNIWFANENESNFELPFNFNTQSGSVLRGSDIDSNELPDVFTKVAPGAYPCIIAYAVVFLVAAVGNMIEFLSVWRRLRKRSTAMNRLLLHLCIADIMVVFMVAAVEIFWRISIGWYAGDFMCKLVQYFRAFGLYLSSLMLICLSLDRFYAVCFPLRAVDASRRVKIMLIIAWTAAALCAAPQCIVFRVQSHPDFPAFRQCNSILSGVAAEAINTAISMSFMYFLPILVIIFSYGNIIIRLARESDGALDADNNDRFLRRSGASVMDRAKIKTLKLSFVIVMVFIFCWTPYVVISIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPA3</accession>
    <name>A0A1D2MPA3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000733">
        <property type="protein sequence ID" value="ODM94920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPA3"/>
    <dbReference type="OMA" id="FICEERK"/>
    <dbReference type="OrthoDB" id="8298415at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904331" description="C-type lectin domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="59268" checksum="AB40C55D95FCD646" modified="2016-11-30" version="1">MTGIIFRIAILHSLLGISFAGMIAENNLESILETPSSKYFLSTEVTDPETATQICNSRHAHFISIENLEENLLVSEKLREIGIETVWLSGIKYSNSTIEDFLLWTGTGEPFSYTNFHESVGESVDMKRSVRDRRSPRSNDDDDDCSCSCTTTLPPPFTPPPCKVPTCNITIPSPICEQLEPQSCIVSRSPVCNSKRDNCTVDCGSKNCRVIKQPECTVTTDKPRCRLESNLGKCETKRPKCHIVKPGTCRAQQDDCVQDDTNTCKPVTAPCKNPCTERPCETIQPPCVTTEPPCVIIPCPTPPSCEKTCKDDKNCECTTQPPCEPIVVCPPPTVTCPPPITSCKRPFVDCSPEFCQSSVQICRPPKVNCPPPRIICEPPEVNCSVPEVVCPDPEVICDEPEIECSKPVVECPDPVVHCDPILTTCESAPVSCSDPLMSCREPSISCQDPVTCDMPPVEPPTRGPCLCVGKKSGKKCGKARGKRDTPLPEAEFVETKQCVAMRKDLGFKWDTQNCDVKHRFICEERKVKKRSVLGFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPB8</accession>
    <name>A0A1D2MPB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nuclease EXOG, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000765">
        <property type="protein sequence ID" value="ODM94704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPB8"/>
    <dbReference type="STRING" id="48709.A0A1D2MPB8"/>
    <dbReference type="OMA" id="MARGHMS"/>
    <dbReference type="OrthoDB" id="5960141at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.570.10:FF:000007">
        <property type="entry name" value="Alkaline nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF17">
        <property type="entry name" value="ENDONUCLEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="7">
        <location>
            <begin position="158"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="6">
        <location>
            <begin position="186"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="419" mass="47633" checksum="60B3C6153A7F38D6" modified="2016-11-30" version="1">MFSKNQLPGLTKLNIRLRNNVFYILIVCYAFVQNASSSSSCRIKWGSSLPVWYPLVFNNAGIIYPHRTGNNSDWSLLIEHNGDFNISCTTAGDFHGYNVSDLKVHCHGATHKTIVNKKPVDFSKLGCKKHLQEKLVAVGKCYNQSTSVDILFQAKYKRLPLINICHNENLDDTIFAHHFIEGSALNKFEVSNKRPTFKEGIFYTKITANNAYKQTSQLKQVESLVCSESLAKKYIDKKRSFYFARGHLAPDGDFVHVYEQNATYFYINVSPQWQSINNGNWKALEFAVRTYAKDRNAKLEVWTGGKNVLKLEDVNGNPVEIYLSKEHKGKLVLPVPEILWKVVHDLARNASVAVFMINNPHLTEVPSSLTHCSCVCPQISWVTWDIKNIIKGYTYCCEIDSVKKLLPFLPEIKSGQLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPC8</accession>
    <name>A0A1D2MPC8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L23a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11891</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000750">
        <property type="protein sequence ID" value="ODM94788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPC8"/>
    <dbReference type="STRING" id="48709.A0A1D2MPC8"/>
    <dbReference type="OMA" id="HTRANKF"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000035">
        <property type="entry name" value="60S ribosomal protein L23a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_uL23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019985">
        <property type="entry name" value="Ribosomal_uL23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005633">
        <property type="entry name" value="Ribosomal_uL23_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011118">
        <property type="entry name" value="PRK14548.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03636">
        <property type="entry name" value="uL23_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L23A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03939">
        <property type="entry name" value="Ribosomal_L23eN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL23 N-terminal" evidence="7">
        <location>
            <begin position="84"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25081" checksum="6E3A5E879BDCDA47" modified="2016-11-30" version="1">MPPKKSSKGKKPAAPPSAAAAPEKKLETTTPKKADTDAKKKKAPAKESAPAKTKVVRKVKVKSNLKPREIRKLVKERTRKLAISKALRTQKKVILSGDDKKRVRKIRNTIRFVRPRTFRPPRNPKFPRKAIPTRCRMDAYSIIQYPLATESAMKKIEDNNTLVFIVHTRANKFQVKAAIKKLYDVDVSKVNTLIRPDGKKKAYVVLDKQNDALDVANRIGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPE6</accession>
    <name>A0A1D2MPE6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease nudel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000754">
        <property type="protein sequence ID" value="ODM94772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPE6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPE6"/>
    <dbReference type="OMA" id="FKTTKAH"/>
    <dbReference type="OrthoDB" id="6417936at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043195">
        <property type="term" value="C:terminal bouton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030297">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21105">
        <property type="entry name" value="GH16255P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21105:SF0">
        <property type="entry name" value="GH16255P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="9487" checksum="E244EE6E7BA30ED6" modified="2016-11-30" version="1">MASSLILKFSECPPADDGMERFACPSTDRLGRYRCVDDHVLCDGFIDCPGKEDEDLQACMFYKTTKAHLDVLADALLRWARGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPU7</accession>
    <name>A0A1D2MPU7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11848</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000742">
        <property type="protein sequence ID" value="ODM94834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPU7"/>
    <dbReference type="STRING" id="48709.A0A1D2MPU7"/>
    <dbReference type="OMA" id="KMAISET"/>
    <dbReference type="OrthoDB" id="8188099at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08317">
        <property type="entry name" value="Death_ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040745">
        <property type="entry name" value="Ankyrin_UPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF141">
        <property type="entry name" value="ANKYRIN 2, ISOFORM U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00531">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17809">
        <property type="entry name" value="UPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00005">
        <property type="entry name" value="DEATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Death" evidence="5">
        <location>
            <begin position="251"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM94834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="392" mass="44384" checksum="1139278556D743A6" modified="2016-11-30" version="1">MDLFMNQVIDLCLYGVGYPLLDDIGGTTRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLVDCRHASHDVTKMATDLYREAIHVPFMAKFVLFAKRIETTEARLRVFCMTDDREEKTLEGQENFTESRDVEVLEGKPQWIEMAGNLAPVTKSGEQLRLKFFAFKENRLPFLCEFEIAMQTCRKNNLHERIQARRGIKYQSVTLTSSCLTKSYQMNLQLQRRYRPHKTAIAHKPTPKQSLLTTVGPGEIHRADLKISDVANLLGDDWIPLARHLGITEPDVSIIEAEYPQSPHQQATVMLRLWMQQAGDRATGNALEKALNSIGRDDIVAKCIGNIAPVTDASEKILAQTHVEGVKTIESQILEPIIKSEKRNLSLDVSYDEQDLMKVSVKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPV8</accession>
    <name>A0A1D2MPV8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Neurabin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_11629</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Synapse</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPV8"/>
    <dbReference type="STRING" id="48709.A0A1D2MPV8"/>
    <dbReference type="OrthoDB" id="62701at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014069">
        <property type="term" value="C:postsynaptic density"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031175">
        <property type="term" value="P:neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06790">
        <property type="entry name" value="PDZ_neurabin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000010">
        <property type="entry name" value="Neurabin-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043446">
        <property type="entry name" value="Neurabin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16154">
        <property type="entry name" value="NEURABIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16154:SF6">
        <property type="entry name" value="SPINOPHILIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0221">Differentiation</keyword>
    <keyword evidence="6" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0770">Synapse</keyword>
    <feature type="domain" description="PDZ" evidence="15">
        <location>
            <begin position="5"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="14">
        <location>
            <begin position="505"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="467"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="242"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM95046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="592" mass="66545" checksum="3BE1C5AB9C8FCF5C" modified="2016-11-30" version="1">MDVFDVELLKGPEGLGLSIIGMGVGADAGLEKLGIFVKTITAGGAAFKDGSIRVNDQIIEVDGKSLVGVTQAYAASVLRNTCGVVKFKIGREQDAENSEVAALIRQSLQADKERDEKRAAQQQQAAQQASVCRPLRRRDFPSPYTLELNRKLLEALSKAEEAETQVEALKTRLLELELAHVTEREDYETRIKDLSTRLRDFEQKQSDMSTESLLEKYNAIKGLVKKFQQREKYLTERQEYHLRKIQERDNEYSAMLNALKDRIRVLEMRLGSSEQEPQNLSFSISPLQLSPIERFNDVWVISGEEEEETSDDATELFDKFVPKHETLDSTCAKDKRDAKKKRKVPEVHRSETLEESLISHVSPVKNAHKIDTHSVGSPVMEVPPPLPLSPPRGFDSSPIRSVQQPTCYNDYLAIQETYGKHYEVDLLALNAMRNRSFQSRDPSLADKLRATLEYHDNNAPVQCAMPPDHVSSSNVSSSASSNVTGSPASTVSRSNSWVGLSPNEWGNEQVIDYLHHLHLDHLIPPFMDHSITGPKLLNLESKDLKSFGVSGDDKMKLKKKIKELNKSAAKSVNSSQQSNQRFYILKKFVNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQW7</accession>
    <name>A0A1D2MQW7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000678">
        <property type="protein sequence ID" value="ODM95396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQW7"/>
    <dbReference type="STRING" id="48709.A0A1D2MQW7"/>
    <dbReference type="OMA" id="PNVSIYC"/>
    <dbReference type="OrthoDB" id="10030506at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000025">
        <property type="entry name" value="Hexapeptide-repeat containing-acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF23">
        <property type="entry name" value="ACETYLTRANSFERASE C18B11.09C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Maltose/galactoside acetyltransferase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="227" mass="25597" checksum="A65902A77C5203FB" modified="2016-11-30" version="1">MERKVMKVPEITDFPPLPEKSLYQHLSHRERMVGGFPYTPFDTELTRMRRQARVLQRKFNDTVEDDVEGRREILRQLLSPDCRHNKIYIEPDFRCDYGVNITIGDNFQSNFNCVFLDCARITVGDNCLFGPNVQLYAGTHHIDSLTRQANDDYVETAYPIKIGDNCWLGGMAVVLPGVTIGNNVVVGTGAVVTKDVPDDCVVAGNPARVIRKMPPRTTVTPKKNATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR90</accession>
    <name>A0A1D2MR90_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thymus-specific serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000644">
        <property type="protein sequence ID" value="ODM95619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR90"/>
    <dbReference type="OMA" id="LVCNEIG"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF38">
        <property type="entry name" value="LYSOSOMAL PRO-X CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="378" mass="41821" checksum="F7395938686C35A7" modified="2016-11-30" version="1">MLVVLEHRFYGQSWPSRNSSMEVLQLLTSQNALADAAYFIDDFTASRGLNGSNWVAFGGSYAGNLAAWMKQKYPDVVKTAVASSGPLLAVYDFPGYLETVSEVVKALDSPCYDKVYDAFNCMESLVNGSSCGNYTSASEIIPALRQCNSVDFGDLLDRETFFNILAMGGWADNWPSSGVRRNCAIINRVAGSDPLSLYGNFLVEMGEGGNCKVRAKSSVEATEEVLKFIRSEEGKQSGAAGWFWQTCYEFGYYMSADPKNGLFGYSTFSGWPYGISCGYEFGPSFTKAYTEERIAMTNEYYKAKNIDSKCVILVNGEYDPWHTLGINSASETSPDNYVVYVPQAEHCDDMLNPKTEEMRKAQALIQTQIGIYLNDSNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRD2</accession>
    <name>A0A1D2MRD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000666">
        <property type="protein sequence ID" value="ODM95482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRD2"/>
    <dbReference type="OrthoDB" id="8255599at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.340">
        <property type="entry name" value="Metallocarboxypeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036990">
        <property type="entry name" value="M14A-like_propep"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904435" evidence="3">
        <location>
            <begin position="19"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="552" mass="63791" checksum="E532CC6E23DD3B67" modified="2016-11-30" version="1">MKHYLVILLFVAFTSIQSADIEINDRKLYRFVPESEDDLFFLKTIRNLEPSLIFWNGIGETGEPVDILACPYTLDQVFRDAPLSLRKSFQTKYSDVEIEFSEDEDEEKNEENILSTPALIPQQDIPETNLKTGTYYKIGLKRFPNGYVRTTPDQNSTRDPHTYVIIDKEAATNPQYQSGGAHYDDIQWYFVPSSVAGWYLLRNRYTDESKAYATWSRNWPTSEKKNHVYFVMQYKNQEASENLPNSNDNFLWKPVRTSEEGKYRIMMKDFTNDFVTWTEQKYGEIAHYLQIEYSTDVKYRQKYDQSHEWWDDTLFTFEPIETTTQAEVKQIEVDTKSFIDDGLMPLYMKTECDHDSSKNLSFSNRGSIVDIQSLQQTSKLQGRLTLRLRDEPFPNSLDFKNAVLTVPWSTNYNEIESQKQTGGNFSLKTKEKVDFFTDVVIPPFTKRILQICYQYIELSLSDQAGIPIQAVVEAFCATDRPSVDFKAVSSRGNTKCVEKELQDKMSTMVELGRRPTSVIFSLDGTIISGLFGYQGIFVPVLSRSGSVNTIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRH2</accession>
    <name>A0A1D2MRH2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat and KH domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000664">
        <property type="protein sequence ID" value="ODM95491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRH2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRH2"/>
    <dbReference type="OMA" id="TIMSSEN"/>
    <dbReference type="OrthoDB" id="10071877at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000080">
        <property type="entry name" value="ankyrin repeat domain-containing protein 17 isoform X3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051631">
        <property type="entry name" value="Ankyrin-KH/SAM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206:SF8">
        <property type="entry name" value="ANKYRIN REPEAT AND KH DOMAIN-CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23206">
        <property type="entry name" value="MASK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="343"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="427" mass="46472" checksum="F6A6E376D345D2B6" modified="2016-11-30" version="1">MTNGEVDESLERDESDEEEDDDEDGLEPSGFLIPPDPDSASIQGIPPDAQARLEAFFEAAGFTDGKLMSDPENLRKLTLTVSSALGEASAAINRMRDSQRKSMEEGRNDSMEEGDSLLALACSSGYFELARVLLAMGANVDDRGSKGDLTPLMESASQGHLELVKLLLTHGTDVNAQSACGNSPLMYACAAGHEDIVRELLKAGARVEDNNENGHTPLMEAASAGHVGVAKVRMKRKRNSFSVYSVVYNFHYNGFFVGTQILLEHGAGINTHSNEFKESALTVACYKGHLEMVRFLLEAGADQVQHKTDEMHTALMEASMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAELLIERGANIEESSLRWPQFLRFTLQRKSTMGIVFRFLGKKANKAYTIMSSENRQVGTIAYRIGCDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRR1</accession>
    <name>A0A1D2MRR1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">von Willebrand factor C and EGF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000648">
        <property type="protein sequence ID" value="ODM95588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OMA" id="CTCINTE"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036122">
        <property type="term" value="F:BMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030513">
        <property type="term" value="P:positive regulation of BMP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052424">
        <property type="entry name" value="Kielin_Chordin-BMP_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46698">
        <property type="entry name" value="CROSSVEINLESS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46698:SF4">
        <property type="entry name" value="CROSSVEINLESS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23334">
        <property type="entry name" value="VWC2L_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00214">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57603">
        <property type="entry name" value="FnI-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="VWFC" evidence="5">
        <location>
            <begin position="28"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="5">
        <location>
            <begin position="87"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="178"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="408"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="656"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="945"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1140"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="945"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1140"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1537" mass="166207" checksum="B10C1C1C86FDF19F" modified="2016-11-30" version="1" fragment="single">PINRQVGISDNVYMTTQNGTDGFEQRVCSIDAVTYLDGETIPTSSPCEHCVCRPPGFACTITSCEYRPGCKAFRRSDQCCPEYQCECEKDGKIYQNGEKITDTNNPCEACYCQGGEIICAVIDCYWRNDCPPRYIDNRCCPMYDHCPPPSAQGPIRHRLPQLTSTLSPISWLNLTLPQSTSQAPSVETVATSASTTTTSTTTEAPSSTDATVVNDSENDIVSTDIVHHDEDVAVVPPVESLSVEPVQSNDVVETSSSAPVETTVGVEQELNDEPTEPLVALNDDGAEESDPTVEPTSVTENLVSSTVIDSTTLFIAPALVLTIAPTQVQETIVNTAPTAQPDFAAVDENRLSDDATTVASSDAEVSDDEPVATTNTPLIPEVQQDFASDSATTERLLDDDVATEIAPAVDTEEDEIPAVSDDANSQGESVTTETVPLSDDAIVNENPTTERFNDDISTDSPARSENDSEITTESPAQDEEALPATTLPPRSNIIQNPDELTRTDLQPEGFASGESVTNAAPVVYSDTSDGTTPAVILENELRNEDAFTTVSPSNIRNVEEDESNQVLNDVPATTSNILQDEQVTATPSSISLDDEHPINNDDIEDNMQIHDATVAPVYDDVTQVPQLDIQDDEASTQAVVHFNDEATQVPLLDEVANDDTTQPPNDDVNDVTQPPVLNDDVPVTQEPQQQDEGTDAPQHDSVIFSEDDATGSPQSNVLNDDVTQGPEGELNDEATVRSHAEEAPAELALEEKADVLSQDETITEVPVKAVQVQDGIDIILDDEVIPSEPEILNQVREVTDVHLHEPTAVEIGQPEAYKEHELYHGVRNADNDTVEIVNLSAAPIEQEALVPTTQQPLELNNDLEGEEVSQNDDVSSQLNVEATTVQNLDALSDDVPEVSTIVNDDLIQNDESVQGTTEGVLHEEGGIFNDEVQVTTEREFRSEILSDPHHEEGHVHEESERTTASPSTLERERSDLVVKDEEAAATAIYADEQTTSLPIYRNKVQKVAEALTAEVIAPESGANKFRLDPEVFKGSLEVTDSLVEATTYVPSKDLLRSGLGSLEIVEDAPQTTLRSLDDAPAAFRDGLAELTTQSPSNLRADLDELTTQSSANLRADLDDLTTQSPSNLRADFDLEVEVSTQKDVENHPANDDVTEGSGLQDELPTTPSARSGIHFDEVVERSGVTSSSLVLNDDIAEVTEGSGSAPRLDDEYTPTTSAPVAFDNAENEIVPVNEASASEPVTTSYAFRMDLLNSLEATDSNADIIENDVPKPTSIPQVAAVDDIANNPTEAAVRDEQVTTEAVSRLRSDLDITTEYTAPVSRDDVPEQSTVVSEILRADSDFVEVSTVSPSGFAAAFRDVRLAGEEIEVANDEPATSASSAQTYNDDETTPVVFADEPEVSTENPSEKLRTEAVEVEQQTEAIANDDTSAATTISSINNVNESDSASQLLNKVRKEGVSLPEMGVPKIQPISPDLSRSNPHELRFDFQLPPEKDSSWYSRAVNQFRRLSGFGSDVDSRDKSTSSVTTKFPSRRFLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRS9</accession>
    <name>A0A1D2MRS9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sex peptide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11166</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000661">
        <property type="protein sequence ID" value="ODM95514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRS9"/>
    <dbReference type="STRING" id="48709.A0A1D2MRS9"/>
    <dbReference type="OMA" id="CHAASDM"/>
    <dbReference type="OrthoDB" id="5864054at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019427">
        <property type="entry name" value="7TM_GPCR_serpentine_rcpt_Srw"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053219">
        <property type="entry name" value="GPCR_Dmsr-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273:SF4">
        <property type="entry name" value="AT19640P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273">
        <property type="entry name" value="MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10324">
        <property type="entry name" value="7TM_GPCR_Srw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="69"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="426" mass="48174" checksum="9CBD39828DBB59A0" modified="2016-11-30" version="1">MVDDSVEYSLQTFSTISTMNDNFVGESSDEIINATQFSYCGAGLKAFGDAYSLFHGYTSLVVCLFGTVANILNVITLTRAQMRNPTNAIFTALAIADLLNMTEYIPYAIYRIYFSHQKTYGWAVYVLIHSHISQVCHTISIWLNVTLAVWRYIMVTCPLRSRALCTMARAKFAIALAYFISPVLCIPIYLNFSVKEIVKNGMDMGNSSGGTGVEYQYVVELSNFALENPALKAVNFWFYSVVIKLIPCAILSVVSIFLILSLIGRNKQKSQFLTNRLGGGQNDGENEICGFDRTTKMLLVVLLLFLFTEFPQGLLGLFSGSKGEGDRYFRACYMPFADLMDFFALLNNAINFILYCTMGHKFRETFSQTFKVQEIKKFWRQRALQNIHPVDETPKKPYVILVPLPNITQFRSVFEGKDPFVIETLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRX2</accession>
    <name>A0A1D2MRX2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serpin A3-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10851</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000614">
        <property type="protein sequence ID" value="ODM95830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRX2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRX2"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904450" evidence="5">
        <location>
            <begin position="23"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="6">
        <location>
            <begin position="33"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="389" mass="44251" checksum="60A81201F11AEDA5" modified="2016-11-30" version="1">MKFPYIAIAFILSLWSFDYGKAEVATTNNQLALKLYYHLAKNMDGDFLFSPFSLSSLISVLGSMAGEGTVERITGAMDYADDYESVTNDYKRILIEFQKLESLNETVLELQQKDDLKLSSDFKRLLVKYLFDIAPLKFSAGSGKTQSEEDNYLTTVLNLGNRTETEIDQLLQLKSTINFKGSWARPFNPISTKPSPFYNMSRRPYLVDMIEDPESRIELLVFLPNSLTGLNDLETKLVQQPFSLTLREFTGTKDLFVYMPKFKLRSELDLKAALRQVGLHSLFVSENSNFSKLFQGNVKPQSFGVLKTSHFGKFSVDEYGTNGWARGFLGSQPAITKHLSPDVFRVDRPFVGVLYDSTRHVVLLMFRKIDFESIDPNRIAIPDAFQAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRZ0</accession>
    <name>A0A1D2MRZ0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.135</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11208</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>3-O-(beta-D-galactosyl-(1-&gt;3)-beta-D-galactosyl-(1-&gt;4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1-&gt;3)-beta-D-Gal-(1-&gt;3)-beta-D-Gal-(1-&gt;4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24168"/>
            <dbReference type="Rhea" id="RHEA-COMP:12571"/>
            <dbReference type="Rhea" id="RHEA-COMP:12573"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132090"/>
            <dbReference type="ChEBI" id="CHEBI:132093"/>
            <dbReference type="EC" id="2.4.1.135"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.135" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000666">
        <property type="protein sequence ID" value="ODM95485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MRZ0"/>
    <dbReference type="OrthoDB" id="19493at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015018">
        <property type="term" value="F:galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050650">
        <property type="term" value="P:chondroitin sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005027">
        <property type="entry name" value="Glyco_trans_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10896">
        <property type="entry name" value="GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10896:SF50">
        <property type="entry name" value="GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03360">
        <property type="entry name" value="Glyco_transf_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="1426"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605027-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM95485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1543" mass="175837" checksum="ECE492290082C619" modified="2016-11-30" version="1">MCVSLSGMCDIWRCACLKIITAIRFPGVLLERKPAQDDDDEISPPLLVRIQTIDLQNLDFQTNVGSTAKFRHLTYIEATNLFLFVGSTSGSVYVFSRDALKFLFIIPFKGGKVCNIACSQDESDIAVASIRGQVSIYRISPNVHYMQSSTSCPLIDAFRHIYDIPHHSAEITEQQWSPNGKYLFIGDSNGLITQMDVACLDEFPRPVPSKIILKLQTRVLQIECSFPYLAICTLTAVFLCDLEKEDFTRIQHKKNTDIRSTGICLMILPERSSLRDLYKERMIPSAKLMLFIGEVGCGTVHCCGMEGNIQQSKKIMLSNKVNKYSTPMFDPTKSTVTTSQIEEEEDQVNISLGKMLCTDDGMIVSVSNNRLFVYDPYTLNVIVWNEEFNRINNFKIISNYAFIWAGNKLEVVAFTPFRTYGEQLFRAKLIGVLDNWIVHTVYSLGWRVTSSPPNGDCDSGISEASGPKPDDTLEKAEWNFRKMMFSEGEEENEFTQYVIKQLPFPLEIAKSDDVVEPVPEAEVSSIIMEECRKLDKNVRSFLARVTAAFESASIVPPGVLASSSSDNHSNSDNRISSALSLVGKKQFSGQNEHFHLFCQIYKGLLRFYEDNDVTLPQLDYKSSDLTLQHVLNSAQSFLIQPKLVNLIQEISEISEISRFEDIIIQLIVCLYAQQKSATDTLELSKTNSLPFVCFTKFTQCPVVIQWFRELGISPANLFYDGVLADTLLLLLPLCPKNDDDLMLLSSSLESIGAYEHLPKYFITWLFLCRFLHKPKQVPYSPLLRSLLIEQLFDKLAEEMFSSGIYRDFRLSTFGNAAQYLHHFVSVVVLLSKSPDCSQPRNVSILLTCFPLNKWAREDIVTKIIAACHLNPSLIGLYLKACLEDGHSMKLCACGIQSGYGSLEDRIPSWQRAIEEAIIKLLLEEYFKSSPYEEDAEEEEEQQDGNGNTTQKRRTEMLIHMFAMKRGVLEPFFRTIADEFLSEEMQAELIVRSGNCASLKYFPCNQQNMSLILRCFQNHFVQPPGGISKISEKSKNLTLNTKQTVWKTQDSDNNNAAPKHAKNGRKNKCFKCSSSLEHFSRNTLSRNCLGLWALKHVGSLERLLEIIQSCHLNVPAMFSARFYQAVVKFHDGAHKGGLTHEYDLDSMGESSLLSCSNFHENKKLKSQKVLFSFTRILHNTQESGMLIMLTPKVRRLLTNKYIGEIIGPFVIGFSTVLILSWIHQTLIALTSDTPRRNATLPETFTDKNGQVYLKRHGMQTEEDIYRLKTDKKYYGIRADAGNGFRRIIVDSSKDSLPSPPGEVWSWPRIEEEADPNKLVWVVTPTYRNPFQYAELTRVAQALYPARKFVRWLVCDDHTKSSGHPTHIKDLRRLLLQFNIKFTLITSTARPKKERIMFNPKGVEGRRVALEFIRRRKLQGTVYFADDDNTYDSDIFRQIQDTKTVSTWPTGLITDWAVSSPIVNAEGTVVDFFDSFRSRKFPVDFASFAINCSLLHANKKANIPWVQGYEETYYFFRKLGHPLDFNHWLQMQLEAKHYISYSIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTH3</accession>
    <name>A0A1D2MTH3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000565">
        <property type="protein sequence ID" value="ODM96198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTH3"/>
    <dbReference type="OrthoDB" id="8609993at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10201" checksum="493A344A992CF8AB" modified="2016-11-30" version="1">MVHTEKSDKYSRDNMLTLNSNSDPFASRKDMGQSRPCAKVMKSAEPSAKPVPTSSSASFKSQSSKAGSTPTSGQYGSWGPMFKNKDNFASLHFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUM4</accession>
    <name>A0A1D2MUM4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Esterase E4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_10068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000521">
        <property type="protein sequence ID" value="ODM96611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUM4"/>
    <dbReference type="STRING" id="48709.A0A1D2MUM4"/>
    <dbReference type="OrthoDB" id="9000293at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="145"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="385" mass="42916" checksum="B19D8E25D0576144" modified="2016-11-30" version="1">MISSDDSNSLSLDELQKSLLRNTAYKSGFPSSVKKFFIHIPILSNCKVTCEIMFFYMISLLCTAVPCAHVINTEGSVTSDVIPYTLATSTDVSTLIPTETENRSLSGRALLPTGKNKFFINQLNIPVHDEPALSKEASNLLENPNPIISIKDGYLRGFIMETISSRPFAAFQGIPFAQPPVNQLRFQPPQKNFPWTGIKDVIEPSPQCIQADYIKQYQVHGVPLGKFFTLLNIAIYSIEQIPKYSQKERLPVMVFIHGGGFFFGSSSIYGPAYLLDQDVVLVSVNYRLGALGVSKKCFNRVTMSSLTLTSTGQQHKNITFNLTMADCIPFPYFTRPAALKPTHTYNGFRMSNVVCHAYIKTSIHSTIDYTKILAHRGNAVRVDQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUM6</accession>
    <name>A0A1D2MUM6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000532">
        <property type="protein sequence ID" value="ODM96514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MUM6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000005">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF565">
        <property type="entry name" value="MOCA-CYP, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1964"/>
            <end position="2129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="598"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1416"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1678"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2136"/>
            <end position="2372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2447"/>
            <end position="2469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2481"/>
            <end position="2519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1424"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1446"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1484"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1694"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="2136"/>
            <end position="2147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2209"/>
            <end position="2226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="2227"/>
            <end position="2246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2247"/>
            <end position="2277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="2278"/>
            <end position="2302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2304"/>
            <end position="2352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2492"/>
            <end position="2501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2609" mass="294020" checksum="2EC2E05FF8E734E8" modified="2016-11-30" version="1">MKFMFPMLRSLAYEFVAECENLGEVSDLSVDVIKNLISLWNRLRQGYEAVDFKNVDKCLESLLICTAHLVLNPQYMKPKKVPPNYRPELKTAIHECGMKFSDSAKRKSICLGLASVVCEPWGTQEFLKIYGGLKADTSNFNVSPTDVDALWNSEGWIFLESRVNCLVKSKSKCKDRHTALGPVCTFLNILVKKGQEFYETNNFIAKPPVVTYDPFKFPFSKYLEYLEVYTILSSEGFIDAQNITSCSDKTMLGVINGLTKKAQDPNSSRIFQQLIFWNGAASAALFLAKAATWNALKSEESEMVHEYFSEWLHLHAESVEVDDFSPLREIIEKFDEVTSTANVYRVANAAVEFHGENRLLTPVYLEVFIRAMTKEYNIINDAKSQNNNKVRVRELERKFSRPYVQLARFFKDHVPTSKDCLLTAFSLNPCVKLFKCLFPKSELANSCKDEDDDDFLCTELADIRDVQYDMVASDNDDLQLSRPDIQDDLHSIIHNPQYKGLLWNSDEEKEALCLKLLKNESLDVIDNQTLEYVNVDYEKYKDLPSLYDPDDDGIEKGYREEDRQQKRINNANARLNRKELMNKAAKFKSLKIKKELNGESNYGPGKVSKKKLNSALGTARRGRPSKSKSELEVALKNGYKAKQLTKFKSVRLGNELGQCNEKEVREIPNYVLQTSPWFPRKSEDINRLTYGELFIKHVRTYPHDYKERLLGRHFEIENHLITSVQKTLGSRPISQQFGGSQCHPRLSTVAVYSSCNYSYDQPSSSSASTIQVAPMSQFLHQSPPQLALEATEDYQIRRLQELIVKMKQSNQKSQVRKHVPQKGLTKVPAESILHNPSSPNDNNNKLVLVPVPEVLPVPVADVIPVPVAEVLPVPVAEVLPDCAFQIMGRYKSHTPDSASGRSLLRTPPILSALKQEDMRAVVGSEAVSCKSTSERSRVIRPFQLQTEPPFRSHAIRPPEETRPQSMVVKLIKKTYPGSKAKKLVVIKPEPPVDAYKTVSKPKAPVVPVLSNGFQTGVNVSADPEGCGVPKPENTTIFPVFQHAEAATTLYSFAKIPKVAVEEINDEIEVKECMQQLLESVDQREKLSDNLNTEEDAATFNSKINNNLPQINTEKSKAPVLLSNGYQTGVSVSSDPEDCSVPKPEDTTILPVFQYAEAATTLDSYARIPQVAVEENNDEIKVVKECMQQLLESVDQREKLCDNLSNNEEDPITATAVVNDVVPQINTKKSMEYFDKEHFNGVNNSTVECATTPPFPSATNSLSYVCNDVEVMDVYDKNSMVDTLAAPKAVNMFGSEVNHSYLVAEREEPNYIINEHAIPRPVTPVEEVEALYRRIQQKLKRKNKRPYEDEEDEIKIAPSVVTHFEQHGKSLRSILSCVLRLEKLSDDQIPLNSRCQFPVKRSSRLKRKKMRTVEAIQTEFQTNIPKEDESSRSESRESSPEIQFIEEIVKRPPPDRSKTSKGCIGEIIKKPPADSKTSNTIIAETVKEPPLDSSEREGKRLETSNNKTNLFRGFHPNGMKKITKQNLEDADHQVKPEVQISDVPDVMQHDNIDLDNHPNSEFFDETSTIHDDDNDFQVALAIQEDDDDEEVAFAIQNDTNNEKAALSTGDGYDDEKVALSIGDGYDDGKAVLCIRDDEDDDDDEEVALAIRGSNEEFEENVPMQILDEDIQSSIAETQIQVSESIPQGDYMPIPTNETGSQVSDSFSQEDYMPISKEETESQVSDSFSQKDYMPISKEETESQVSDSFSQEDYMPISKEETESQVSDSGPQEDYMPISKEETESQVSDSGPQEDYMRISTEETEIQVSDGISQEDNMQISTEETEILDSDEISQECNMQISTEETEIQVNDDIPQDDNIMQISAEETEIQVTNDIPQEDTMQIYIETERPVTPSNMSINNDSSLNVSPAITIPVLQPMNSDYEMHSDSDDEPPVLEMTVGGTMEEAGDTTAAGAVSSGEVLPRCYFDVEIGGVSAGRVVFELFSNVAPRSAENFRGLCTGEYGIGKTTEKPLHFKGTVFHRVIKEFMIQGGDFSKQNGTGGESVYGGTFEDESFEMKHDAPYLLSMANRGKDTNGSQFFILTQAAPHLDGIHVVFGRVIFGQAIVKQIEGLPVDRKSRPLQDVRVADCGELVLVKKKKKDKKPKKEKKRVSESDKSSGELTDSDSEKEKKRKQSSSDSDSDNEKSPKVFCSVKEGTVPPVPENRFLLRSFPKDNDKEKEKGKEDDKKHSRRNRSRSRHRSRSRSRGRDRRDRDHRSGNKTEKETPRYGRVGRNNDGKKVKGRGRVCYRPVSKSRSRSRSKTPPHWRAEARRVISMREYEEKEKQRRQRDDEIRRRQEERQKRHEEMGKSKDDSNDNEEVADSEDKPKDIVLAPDVSEADKAVEELTAQIQLAAATNEGVVYYQHLYRNRGASEKADPEPAKIVDATNIQGFEPITSYSSTVVDDASVEKAAESGSGVDEGLPSKEDEEEELRLRRELLKKRMKDWEDSSSDDDQSHSKDKALVNKSSNDASSDVKAPIARRISREDVRERRDSHRSDLRVEVVAKVELDPVATILQNAVQGQDLVPEVVSAGSHVPDLGNILDITIVEEAGGLDQEAHLVDVTDVYKMDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW32</accession>
    <name>A0A1D2MW32_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000458">
        <property type="protein sequence ID" value="ODM97269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW32"/>
    <dbReference type="OrthoDB" id="10535740at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904634" evidence="1">
        <location>
            <begin position="24"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="274" mass="29281" checksum="1C529406125CEEFB" modified="2016-11-30" version="1">MHFKISLSCLVVLLSCIITWTAGQDAGDTASATSAATTTAPKTSPKNEPETVAHFIRAVMKKYGEAKAAEALQSLDQLPLGLTMKILLVEVDKPLATDIVAMQRYAQGSDKTLITMIGRIVAGDKTVPKEIFLMDQKLMKFPWWLRIRARMFSNLEKYVAAYSLVPVAAKAAVNGAKTKGSDIPAVVGDETKSELAAAVAASATEAPKQEQVAVASSTASQSVEPPQQLKLSLLTPIQQQQILETLALAKSVQATNANPAIQTQSQTNPFLLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWI4</accession>
    <name>A0A1D2MWI4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inhibitor of Bruton tyrosine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09294</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000448">
        <property type="protein sequence ID" value="ODM97386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWI4"/>
    <dbReference type="STRING" id="48709.A0A1D2MWI4"/>
    <dbReference type="OMA" id="IWYENTE"/>
    <dbReference type="OrthoDB" id="1893551at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18500">
        <property type="entry name" value="BACK_IBtk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18301">
        <property type="entry name" value="BTB1_POZ_IBtk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF2">
        <property type="entry name" value="INHIBITOR OF BRUTON TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="114"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="171"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="225"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="274"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="553"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="720"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="943"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1030"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1039"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1073"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1243" mass="138185" checksum="B0FE353AF11EA7B4" modified="2016-11-30" version="1">MASTSRSSPPSSPAPALQQKASSSQKHHVAEDDPCTDRCRSKEHGRRIWMIAQGSEDDSEVVALWSKTCLNYSQVRDDFGRTALHAAATNGLLKAAEWLVKIQQCNINAKDYISGYTPLHRSIYCGHLQVARSLIKLGADVNVRDNEGLTPFELCQMDRPIPFKQNAGDMTELTVWGSNANYNLGLGHQQPRLVPDVLEKFRKEDLSLVQVAMGTYQTMFLTKTGKVYACGYGMGGRLGTGNETTVLTPSLVHLKSACKIIAVGQDHTVFLTDNKVWTVGSNDFGQLGQPKECHKLLTPRTVNSLSKFQISGVLASSIHSVFYDQSVVIMCGANQGQFGKQTVSDRLQLESSQQMQQGLITTVSGNEQCTAICVENRYLYLLRRYQHARIDSRNTTSQKITKIEVSGEKDSITLFILTSSGRVLIWRENYNPSTKEHKGAFTRLVFSSNRLLDVKDFSVNQSSIVVITTLEKPTRQGGTTTIPQSSSAPWKSAIGPGWPLRLSVSSDVKGHNFSILQRHQIMDVTDIPYVGGSLMKDDILELYTTMVEGDGIHDLTFEVDSFHRFPAHAFILCSASPVFQKIIGDHLPTSAEEPVVIKVTNALFGIDPQKHLSLQDGKIFKAVLDMIYTSSCFVTSDEYILELRNCFLMDDERKGATFGEKLKDIMKMRQLCRALELEQAVEQLQEVLVQIDSNAFPQDVPKIRLPLSRHRFNRVEGDMCDVYLESSDKVLIQAHKCILVARVEYFRSMFSVNWSYGLPTASKSKPMSLPFSAKALLSVLDYVYTDKTVVNDGEFDLTWEAIACSDYMMLDRLLQIYECEMTKNINLKNVADILAFAWKHNSDQLRNTCFDFISLNLTAMLENKMLENLPNEIVVGLGSYYREVQARNLNYARTLHKRDEANIPNATDYSCALEMTPAEVLEQLQVIEETDAALLQKKSVSKPTKSRVRLRSRTLSESESLQDNDESNKELLLQIDCSIPENKLSTPLGSPAQAAFTPERKYIVPMPRNSMPVESPKPAKSPIKIDEFPSLGAAASSSPPTRGFTQPRRTSFEGSTQPTLAQSRDVNMQPLVAQGSSMASTSPSGSSNTPPQPIKQSPATASSSGAKKKTKWRAIKSDKDILSKSPVATVSGPSSPPALTSDGRDRNNPWKVKTTKQVTFKDIVDDEVEKRRNFEKAVSKPLKLMQIEDEAINVLTDMYTSEDTDDFIELLTVERVVASNVSAPTWVQHAGALATMMSPDTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWR7</accession>
    <name>A0A1D2MWR7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000438">
        <property type="protein sequence ID" value="ODM97489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWR7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM97489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="74" mass="8253" checksum="09CAC027A5CFD236" modified="2016-11-30" version="1">MNTNKDQRQKRKFTLPSLQNLLIFDAEDGPLSPKAPKSPKIIKGSPNRGRLPTCSICIDDLIIFDEEPVGESKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX86</accession>
    <name>A0A1D2MX86_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tyrosine-protein kinase</fullName>
            <ecNumber evidence="11">2.7.10.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_09026</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 11">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Tyr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000424">
        <property type="protein sequence ID" value="ODM97653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX86"/>
    <dbReference type="STRING" id="48709.A0A1D2MX86"/>
    <dbReference type="OMA" id="RDPDYQN"/>
    <dbReference type="OrthoDB" id="67310at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002009">
        <property type="term" value="P:morphogenesis of an epithelium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000027">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050198">
        <property type="entry name" value="Non-receptor_tyrosine_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24418">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="SH2" evidence="13">
        <location>
            <begin position="15"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="13">
        <location>
            <begin position="291"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="457"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="720"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM97653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="768" mass="87420" checksum="AF1D7455402B15FF" modified="2016-11-30" version="1">MSMSSLAGIPDDDAWFHDKITREDAEALLREVGEERAFLVRESTSCAGDYAISVYSDDAVHHIQVKRHEGDAFFSVEGREPCHGLDELIKSLQSPTSPDEDIVLQKPVIKSLPPPDVRRHGRTNLLHRATINNNVEIVSEMLRCKMRSIDAKNEDGQTATHIAAINNLPEILHHLIRAGTNVNAKDSSSCTPLHYACRKNFPNIVQILLEEGGANPQIRRNDNGWVPMHEAADQDHVECIRVLYMHNAPLRPRTDEKSTPLHLALRRNNQETVQFFDSVLPHEPMTSRGDWFHDKLGRQDALEFLRACRKASEIDIAASYYLIRRHSLKEDHYVLTLIDPEDKTYNFEIKREGNFLYIDNGPYLESLEHLVVHYSSWADGLPCRLQVPISPRQAKSAMALRRNLNSSRNCLDVPPPLPKRTPILSSPNSLSRICTDVENNNRSTTSFSNENIPNESLEIGELLGEGEYGEVYRGRLRTSLQEFLDVAIKTLKTEGEMSDWKKNEFLTEARTMLDLKHNHIVRIIGICWSPKTYMVQELCELGSLQDFLLDKADIIVPGKHFRKWANQIAQGMVYLQDRRFVHRDLAVRNILLSSVEVVKISDFGLSRALGLDSEYYTASQGGRWPIKWYAPESCTHGTFSHATDVWSYGITLWEIYSFGATPYGDMPGKEVIDEVEKGYRLEKPGHCSDPVYRVMRSCWSKNPVLRPTFRFLQNFFETTNDNDEVASPPRNQLNISPLPPPLPVTPEPTRDVNLNVDNTSEVSLMSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXN2</accession>
    <name>A0A1D2MXN2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08872</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000409">
        <property type="protein sequence ID" value="ODM97806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXN2"/>
    <dbReference type="STRING" id="48709.A0A1D2MXN2"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="161"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="49760" checksum="5FCA2F703CC43923" modified="2016-11-30" version="1">MATSERYVSLVTQWGTKLSEAIKKLRQQENLISSLKREKFVLFEQVAAAEATAREQFDEERGVLLVRHQEEEEKLRNDYNHQISSLQRLANQLTEEKAELEKKVLRFQNLASKNGEEMSLLRVQKLEDEEKLQKYYKKKISLLQMQLKLAEAKATSSNLELSTLQLKVGKLEKKVVSLESELGKTKKGKNDVEMELLQRMKAEMDKLEETFATLDSHKDEETVAEQPPVLESELEAVQEHSRHWSISNEHEDIIDVESNRTDISDDTNSDPSMDNDEHMDSDDDVAFICEMPEKTSTPKDSAVDPRPNTPGRRECQHAEDISNSGGLYFQCICKRKFSTKGRLATHLRYYQERKFMCRICKRKFHRFSVWRTHMSVKHDENNEGNFGCSNCGVAFSTKAQFHQHRRVFHTSKKEKGSRLDSQCFMNSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXR9</accession>
    <name>A0A1D2MXR9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PAN2-PAN3 deadenylation complex catalytic subunit PAN2</fullName>
            <ecNumber evidence="9">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Poly(A)-nuclease deadenylation complex subunit 2</fullName>
            <shortName evidence="9">PAN deadenylation complex subunit 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PAN2</name>
        <name evidence="11" type="ORF">Ocin01_08910</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 2 metal cations per subunit in the catalytic exonuclease domain.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Positively regulated by the regulatory subunit PAN3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
            <location evidence="9">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Shuttles between nucleus and cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase C19 family. PAN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000411">
        <property type="protein sequence ID" value="ODM97768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXR9"/>
    <dbReference type="STRING" id="48709.A0A1D2MXR9"/>
    <dbReference type="OMA" id="TQELLWT"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010606">
        <property type="term" value="P:positive regulation of cytoplasmic mRNA processing body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06143">
        <property type="entry name" value="PAN2_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000421">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000011">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03182">
        <property type="entry name" value="PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030843">
        <property type="entry name" value="PAN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050785">
        <property type="entry name" value="PAN2-PAN3_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048841">
        <property type="entry name" value="PAN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028881">
        <property type="entry name" value="PAN2_UCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728">
        <property type="entry name" value="DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728:SF0">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20770">
        <property type="entry name" value="PAN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13423">
        <property type="entry name" value="UCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="533"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1026"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1028"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1135"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1188"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM97768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1235" mass="138855" checksum="4DFAA081A7540D08" modified="2016-11-30" version="1">MLGVGRGLYYGPVESGNGPADSTQFVEQVGEFQKTQSVLVDGGDRYGVSALTIDTSEELIWIGNQGGHVTSYYGANLEKYTSFQVVNNQEIRQILTFDDLILILSQTQLRGQIRRGLPVFTHASENFMDMQCMVQTSPTTVLFGGHQEYLVEYDVTQSMESRTAHVGESGCAIMRNHGRYICVGQPSGHIQLLDPRTYGPEQAIEAHSGSLSDFDVHGNLLVTCGFSTRHGNLSVDRFLKVYDLRVLRALAPIQISVDPFMLRFLPSFSSRITTISPSGQMEISETQALTTSNIMLYQVTTSGSMCLAYDVSSSCHHLAFGDSAGSLHLFSSNPAAMFNSYSRETEFADPLPSLPPMNVTDEMACYASVALPLMHTPLLSEWPSEVLQPVYRKAPEVDRNIVQSMKMVGTIGYAPNPGTYRRNQMQYKQNMSGQPHSMSTGMTTSGSISPFGHAKSFSPVPPYLSPNHHANNQQGGYIYSGPGMKATVYTPKHHARPYFHGKFMIPKRYAKIDWKKSFFEESDMESFNRTQFSGLEAITANSYCNSMIQVLYHFEFLRGTLLNHLCKREACLSCELGFLFHMLDQSKSIPCSGSNFLRAFRVVPEASALGLILQESQSKKRSAFIRLIQSWNRFILHQIQTEIGKTESDKKGSNGNSCRTTPNPILPNTDSILKVFVMKQENTNRCTRCGREEKKESEVLLSNMSYSFAATGGGKHCEFIKILQKSISPEQTTPAWCDKCEKYQPTFQSRVPKALPPILSLNSCLDNSNDFLTWKNFMQSLLPDKSPVAEVPEFQPKGQTPVPVPPPNVRSCRYGKNCMRPDCKFWHEGRQGPSKEGETGKASEFDLNPEIQAKWLPKTIRIQIDELNQVLVSDTEESNDIEDLNSDLVVKQRCADYELCAVVIFVRDAENEEKCNLVSIVHVDEPYFERAKQEDSKTGWFLFNDFCVREVAESEAYSFNPKWKIPAVIFYRMKPLAEEFHRQEKQQVITADVFKESSIKNKKLTYKPLSPEEIPKKGEAFCVAMDAEFVTLGQEETELRSDGKLATVKPQQLSVARVTCVRGQGPLEGTPFLDDYISTQEVVVDYLTKFSGIQPGDLDANFSSKYVTGLKSVYMKLRFLVDIGAKFVGHGLNNDFKVINLLVPQDQVIDTVNLFYLPNQRRMVSLKFLAWHFLGMVIQAETHDSIEDARAALALYRKYEELEKTGKLEEALIDLYEAGKKAQWKVPNECDKKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ44</accession>
    <name>A0A1D2MZ44_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein alan shepard</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_08466</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Has a role in the perception of gravity.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000373">
        <property type="protein sequence ID" value="ODM98211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ44"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ44"/>
    <dbReference type="OMA" id="FLDETHY"/>
    <dbReference type="OrthoDB" id="266020at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="32"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="118"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM98211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="265" mass="30417" checksum="DD6298847E1E1413" modified="2016-11-30" version="1">MLPEMEFLDETHYDSHQNATNGMNEESKSEERHLIVNYLPQNFTDKQLYQLFSPFGPVESLKIMRDQRTGYSFGFAFVNFLYENDAKAARHALNRYQIEHKRIKISLARPCSDDIKDTNLFISGLPLTFDDDDLFGMFSAYGEILQCHLLRDKFTKLSRGLAFVRYDKRDEAFAAIRGLNQSVPPGETTPIRVRLAQDHGKQKAAYIAGFRAALIQRKTKHGVPNVEAHSSRSRTLHENGYGYSQDDEHVMYPTSHWHGPRLGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0L2</accession>
    <name>A0A1D2N0L2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Sodium/potassium-transporting ATPase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_07845</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Cell membrane</location>
            <topology evidence="1 18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000318">
        <property type="protein sequence ID" value="ODM98837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0L2"/>
    <dbReference type="STRING" id="48709.A0A1D2N0L2"/>
    <dbReference type="OMA" id="MYLAYFI"/>
    <dbReference type="OrthoDB" id="158672at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090533">
        <property type="term" value="C:cation-transporting ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098797">
        <property type="term" value="C:plasma membrane protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02608">
        <property type="entry name" value="P-type_ATPase_Na-K_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000038">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000003">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000001">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000004">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005775">
        <property type="entry name" value="P-type_ATPase_IIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01106">
        <property type="entry name" value="ATPase-IIC_X-K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14 18" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11 18" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 18" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="7" id="KW-0740">Sodium/potassium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 18" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="753"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="822"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="925"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="959"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="19">
        <location>
            <begin position="20"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00038795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODM98837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1000" mass="110188" checksum="05A0928F103A254F" modified="2016-11-30" version="1">MGTKRKSKKLDELKQELEMDEHKVPVEEICSRFHSDVDQGLNDETAKAGLAKYGPNALTPPRQTPEWVKFMKQLFGGFAGLLWFGGILCFIAYGVDRAGNEEAASLDNVYLGSVLVGVVIITGIFSYLQEAKSNRIMDSFKNLVPQYANVIRNSEAITIKAEELTIGDIVMVKFGDRIPADIRVLESHGFKVDNSSLTGESEPQTRSPECTHDNPLETKNIAFFSTNALEGTAKGMVIKVGDTTVMGRIAGLASGLETGQTPIAKEIERFIHLITAVAVALGISFMIVSIILEYSYVDAVVFLIGIIVANVPEGLLATVTVSLTLTAKRMAKKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWYDMTIIETDTTEDQSGAKIEKDNDGFKALSRVAALCNRAVFKGGQDNIPIMKKEISGDASEAALLKLMETELGSIQAYRALHPKIIEIPFNSTNKYQVSIHEVDGDSRYLLTMKGAPERIADRCTTILVNGKEQPFDSKMRTDFETAYMELGGMGERVLGFCDTFLPTDKYPKGFKFDSENPNFPLTGLRFCGLMSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIARSVGIISPDNETIEDVAVRKGIPVEDVDPREAHAAVVHGGELKDLTNAALDDILINHSEIVFARTSPQQKLIIVEGCQRNGAVVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIVYTLTSNIPEIAPFLCYMCFGIPLPLGTVTILLIDLGTDMVPAISLAYEKAESDIMKRKPRTKQDFLVNYRLISLAYGQIGMIQATSGFFCYFVIMTHCGFWISDLLQIRAVWDSENINDLTDSYGQEWTYSTRKSLEWTTHTAFFVSIVIVQWADLIISKTRRNSISVQKMGNWILNFGLVFETLLAIIFAYTPPIQTAFKTRPLAIEWWGLPLLFSEYIFIYDEVRRLILRKQPAGSWVELETYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0P1</accession>
    <name>A0A1D2N0P1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulatory protein zeste</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07882</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Self-associates forming complexes of several hundred monomers.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000321">
        <property type="protein sequence ID" value="ODM98800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0P1"/>
    <dbReference type="OrthoDB" id="5803015at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028002">
        <property type="entry name" value="Myb_DNA-bind_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13873">
        <property type="entry name" value="Myb_DNA-bind_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="5">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="333" mass="37699" checksum="937D6DA253B4F18A" modified="2016-11-30" version="1">MAMASGEQLKNAKIAVLDLINENKEVLFGKLSDTLTREAKESKWAEIAEHAHALGAFPWHRTWDYLRDTTWQNWRKRFVEKREKKDKHDSTGQGPRIVYDEADLLIMEILESLGKNGPSSSHNNHTNQSAINNSSTVSNPNGAHINDINEVLEIEFDIKNETGNLDGERADEHLLSMNGGDDLNGDNYDDEDMVDGPQQDAYEEDEHTGYQNSNYVNTTTDENSQQPKIISTSSLSRASILRKSAFAAVRSNRKRPASFIVTNTLESSEKELTALKCRKIRAELELLQKDSYKKDLEILQLERSLGLPASDVTRKFYRFPRGNSSIVNNLSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2L2</accession>
    <name>A0A1D2N2L2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000272">
        <property type="protein sequence ID" value="ODM99526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2L2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="7110" checksum="8E81207CF706CD25" modified="2016-11-30" version="1">MGSVQLHYVTCALIETLLEWAFDTLSILMTYGRTKCAFRTITVKYANVTLNSLKQILRPGTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2R7</accession>
    <name>A0A1D2N2R7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Zinc finger MYND domain-containing protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_07097</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000270">
        <property type="protein sequence ID" value="ODM99576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2R7"/>
    <dbReference type="STRING" id="48709.A0A1D2N2R7"/>
    <dbReference type="OMA" id="HQIWDAI"/>
    <dbReference type="OrthoDB" id="6272564at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140006">
        <property type="term" value="F:histone H3 reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034243">
        <property type="term" value="P:regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15537">
        <property type="entry name" value="PHD_BS69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20159">
        <property type="entry name" value="PWWP_BS69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.140.2220:FF:000002">
        <property type="entry name" value="Protein kinase C-binding protein 1 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057053">
        <property type="entry name" value="MYND_ZMYND11_ZMYD8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047268">
        <property type="entry name" value="PWWP_BS69"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047269">
        <property type="entry name" value="ZMY11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46379">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46379:SF1">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24324">
        <property type="entry name" value="MYND_ZMYND11_ZMYD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="140"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="PWWP" evidence="15">
        <location>
            <begin position="337"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="16">
        <location>
            <begin position="649"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="419"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="474"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM99576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="690" mass="77835" checksum="E015A690BB852FC8" modified="2016-11-30" version="1" fragment="single">SDEETVSCPRELKIFLGKYSRSDKCVGGRGENQHISYFDENKLYVDDARMQVTRRQATPSKVHQIWDAIGGQGSQVMDFERLISTATTMHKIPRDEINHQLNFALKDELVVSEVVETQRREETEIYKLPDPATLDKGDHDWYCFHCHLGGQIVKCEDCPRVYHLDCLPEDRKPEKDLFVCPACHIMTAKPSSEKVVVKPKILNQLLQYICDRFKSWQIEMLEKADGKTWALAANRTAKEAWRFGFLVYTPMDLEMMTTKATTGKYVSLEEFQVDCETLVHAIGVYFGLDMLKGGQIGQAFLRDALHDIQEIKLCHDCFRRSNEKNHDWWFCLPCSTPHEVVWAKQTGYPYWPAKVMKKDGNKWDVRYFGGNYERGIIDAKNIQPIETSINQLKVRRTALWNDAFEELSKFQEIAKDPDLAAKLPPKGRSGTSSAKAKAGKRVASQSPEEVAPKKTRKSESSTSTPKTSRKSAGSKASSILQANGTPSSTATTVVSPAKKKGGAANKSASTPARRDSASGPKATAAATPASGSSTKTVKVTVATKEKKSSFNDLHDGNLDPEILQFLQELDDNESLDGDAYFSDEESNELQEKVSEDAVSSSCNESKGTRSVYVQVAHQGLIKDKLVKKLVDMQARQVQEISQNKKKQWCYNCEREAIYHCCWNTAYCSIECQQVHWTREHKRLCRRKKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N393</accession>
    <name>A0A1D2N393_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Zinc finger protein-likerotund</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_07157</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000273">
        <property type="protein sequence ID" value="ODM99524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N393"/>
    <dbReference type="STRING" id="48709.A0A1D2N393"/>
    <dbReference type="OMA" id="SPPSMCL"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000158">
        <property type="entry name" value="Zinc finger protein 362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000648">
        <property type="entry name" value="Zinc finger protein rotund"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001172">
        <property type="entry name" value="Zinc finger protein rotund"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="200"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="335"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM99524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="479" mass="53756" checksum="AF2BFD0C6490F8EA" modified="2016-11-30" version="1">MVRDSSPRLQYSTMALVDSNNSVESYRSTVMNGLQEATSNDDKVFTSKADLQLHTQIHMREAKPYKCSQCTKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCNKAFSQLSNLQSHSRCHQTDKPYKCNSCYKCFVDEASLLDHIPKHKESKHLKTHICHFCGKSYTQETYLTKHMQKHAEKSEKRMARQNNNNNNNNSNNNNHHQTNGKSEPVDIMSCCNKISYQPSQIKKERRNEVFIDESDYSGCEILERLKTNHGTSNNTNGQNHQVNNHQSSNSGNVLPSPEMYWKSDIGESSPPSMCLPSNGQGNILGRQGSEGPDDLRVNNIGQHHPTQPPTPTNPYDALANALASTKSAGASAFTPIQTVVLNNSAMLQIPANMAGGGGPPGTRAVYIPYEPLSFPKSSHHHQMTAMDMKTPGNAFPNQLISLHQIRNYAHQPTMTPEHLLGLKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3B3</accession>
    <name>A0A1D2N3B3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein tramtrack, alpha isoform</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06928</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000257">
        <property type="protein sequence ID" value="ODM99759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3B3"/>
    <dbReference type="OrthoDB" id="2311693at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF99">
        <property type="entry name" value="BROAD-COMPLEX CORE PROTEIN ISOFORM 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02892">
        <property type="entry name" value="zf-BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BTB" evidence="6">
        <location>
            <begin position="48"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="174"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="426" mass="47394" checksum="CD9CBE2347719EF5" modified="2016-11-30" version="1">MEEQNEANFDAGSNGEDAEMYLLKWNSHQNHFANKFSELLDEDEISFTDVTLACEGQFLQAHRLVLSVCSTFFKNLFKVNSAERGPATVVLANVRYTDLENILHFIYRGQVNVRKEDLNKFLETGEQLQIDGLVGQGQSKNSFKRRFSDGGQVVSRNQGSASYMVNKSGAASRSSFHGQYKTVTTSGNSNASRLSSAVTHNNHSHDSVAKKPRISPTAPVARNSNHETGTNNSSRRASTSAHHNNASSPSSISADVACIDAETGSTENSGIKILSVATVNAGYDSQHNDVIEILDYEDDDRADNEVDELYSIVEGAEDGAFYGYQTSYQRTHTSNQQSRHTDSSFRNTLQARYPSIIDGIHFELISADEKRVAAQCKLCPGEKVIRGSGLTSSNFISHLRAFHKRELEEWREKRKTETTRRRQDCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3B8</accession>
    <name>A0A1D2N3B8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM122 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000283">
        <property type="protein sequence ID" value="ODM99415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3B8"/>
    <dbReference type="OMA" id="PMINQLG"/>
    <dbReference type="OrthoDB" id="10036177at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026716">
        <property type="entry name" value="PBIR1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22227">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22227:SF6">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="246"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="46896" checksum="06AC7D0DC1F8A06D" modified="2016-11-30" version="1">METDGDSSSKAFLSEAEQSTSSRSSANIGESMSGTESETAGAGSVNIRSLNSSATATSTAGSCPTNSFLLSGRASSPSPALHRPTRACPSPISSIVGTALNQLNLKRSSSAPMINQLGTGRDEPTSQGMASGTSTAVLPSAGSGLGGAANPTEIDATSLATSFLSSLSGSRPRRFSASFSPGSPGPAPSRVNQLRNEDHPDWETASEKDFNGTSNIAQSWEDLSLDSMSMEVSTRRPSLSDQLWLSMPPTSSASSSPAASPRVLSRFSPSLSSPSPTRKSFTTRRSLSPIAVRPSVLSGGGHGVKRKCDWDSNMMDCSPQPAKRPGGLLSFPMGSPQPIPAVAQTSVPSTCYQPTPSYNFTTSTVVPNSHTFFTTSQAAHPASPFNPNSSTSSGSLVSMVTNHVEDSQNSNETESSVSSNGGRESPFFRPVNSPLQNATSPEDSPHPPLPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3P0</accession>
    <name>A0A1D2N3P0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homeobox protein XHOX-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06797</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000249">
        <property type="protein sequence ID" value="ODM99888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3P0"/>
    <dbReference type="STRING" id="48709.A0A1D2N3P0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052002">
        <property type="entry name" value="Even-skipped_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46294">
        <property type="entry name" value="SEGMENTATION PROTEIN EVEN-SKIPPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46294:SF4">
        <property type="entry name" value="SEGMENTATION PROTEIN EVEN-SKIPPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="3">
        <location>
            <begin position="3"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="272" mass="28007" checksum="E642E21A5BE33167" modified="2016-11-30" version="1">MCPVWFQNRRMKDKRQRLALACPYADPGLAAYILHAAAASANYPYAPAAAASLYQAAYYPHPAVAAAAAAANLPSARALSQQQPGQQQGGQQSQPGQPQHQSPAPGLIRGFHSPSHFSPIAAAAAAAGGVPQRAQNLPFPYLGRSPNLNLAAAAGSPLGQLGLLDDGGNGNSNSSRMSVPIPMSSTSPTSSSSNTSDNCHNCISVDGHSPNGMHSPGFHHHFHHHHLNGSLNSSGSIKSASPSPVSSSSPVAGNTMSSPPTLFQPYKESSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N460</accession>
    <name>A0A1D2N460_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_06843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000252">
        <property type="protein sequence ID" value="ODM99834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N460"/>
    <dbReference type="STRING" id="48709.A0A1D2N460"/>
    <dbReference type="OMA" id="RVFYPVH"/>
    <dbReference type="OrthoDB" id="9975579at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.20">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054833">
        <property type="entry name" value="FormamaseFmdA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045496">
        <property type="entry name" value="FormamaseFmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="414" mass="45406" checksum="44BFA45AE9931A77" modified="2016-11-30" version="1">MVRTIIKADLSKKPQEMPGHNFHNRYHPDIPAVVEVKQDEVFKVECYDWSGGQCKNDDCVDDTYEWDLSIGHVLSGPIAVEGAEPGDILEVELLDIQAHPDMPWGFTAILPEHRGGGGFLGDLFKKPAKAIWDFEGIYAKSRHIPGVRFVGVIHPGIVATAPSRELLDEWNRRESELVNSAPDGKGSSMACLPLPHLAILGKVDKDPAKAEKMQKEAARTIPPRENGGNADIKNLSRGSRIWLPVYVKGANLSLGDIHFCEGDGEIALCGAIETAGIITVKTKVLKNGMSMYGLKRAPMFFPGPIDPYYSRYLTFEGLCVDEDGKQHFVDTTLAFRQAVLSAIEYLTKFGYTREQAYLFLSACPVESHIASIVDIPNACVTLGIPTEVFDFNILPNGDGPKVMVKGSHPPAVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4A0</accession>
    <name>A0A1D2N4A0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000233">
        <property type="protein sequence ID" value="ODN00107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4A0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="18610" checksum="32A9B6EE32C128A1" modified="2016-11-30" version="1">MSHTFYKIWRVCATFVLLTLTLHVDSLPLINLSDSQLPTEGEKRPPQSFVELRESDKSLLRSVALFIGVLVVFSMIICLCATYWCMCWVLQCPGLGVVQSLTRVARHCNVGSRRRIRNEGKSSKGGSADLPPPYEVILACKPDEYNEDEDLPSYSEALCKEVWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N554</accession>
    <name>A0A1D2N554_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000209">
        <property type="protein sequence ID" value="ODN00398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N554"/>
    <dbReference type="OrthoDB" id="10690472at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="848" mass="96022" checksum="B25A4191070F389F" modified="2016-11-30" version="1">MRPSAKKEDNNRSNETQCSSLVLTNPDNKTAVADQQPCCSKSLAYQAIELVQESSPASSTSSGISEEESDVSISPAVQAYSDTAILCNNLEFERYSQQEEEPDSYDPDYHAGSESGSNESTEIHSDAAVLENPVSRKTPQVCLPESVDKDGSNSRILNLSQSESSDRVSNSHEEKMIDRDDNNNPVQWISNSEKKYLEHASYLFHRERRQYLAQTINLLPRSRQFVVFNVFGDFARFMGWRSRKRKKVAFPEEVMEHYHQKGDVAGKDRFVPVAKQAFKGIASTKKRRLSAVYTSFSVKSTEFLPRMERIEDYSKCEHCCERHCVHCDCFKRHKAKPDLTNLMEGYLCDLNGASLFLHGHATRTFESAMSTLEFFRPQPNNRSSYPNMTSSYSKYQLGVLSASVWMFGYSLRQIIQISGVNSETYNKTTIPSEIGFRKLLEQFAAMSLAVEEGVKVVLQHSHNFYHFCKECVRILKVLQIHVSFRCDIKIRLPIRRGDGLEVDQSLKKRDIVKQKAVEVMVARENQAEGEAEQQAELEWKKFGELTGQEKFYAMKHLLNVTLDGMNLVQTQLRFLIDDIVDSVKDVAEADLLFILADMYDRVKFLENVGNRSSTKAEMNQISRLMTEFCKDFQTFVDFGQHIMKRYIEFRDMMHLTYIFLTRGLKQEMLTEMVPGDTFKKKRVLRGCCGCGGAKSRRKTVTNYQPKYDPNDFFRVSYRDAVTAHAVIFANKFHVKLMAGVEPIQSIIPRKLQCSWGEMEGPSPRTSLDEYVELLETDEEHPPEPPKPILVSGPETHSPTGSPVGSPRGSLGDEGTGGSASNLQSSPPPPTSSSPPTKSPKVSIESPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N675</accession>
    <name>A0A1D2N675_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA mismatch repair protein Mlh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05912</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N675"/>
    <dbReference type="STRING" id="48709.A0A1D2N675"/>
    <dbReference type="OMA" id="ANYHVKK"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03483">
        <property type="entry name" value="MutL_Trans_MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000109">
        <property type="entry name" value="Related to MLH1-DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="6">
        <location>
            <begin position="247"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="734" mass="83186" checksum="51C3C55AB41025F6" modified="2016-11-30" version="1">MILVLILDFPRTTRKLFRNFLWIGDKMAKIPGKIKKLEEVVINRIAAGEVIQRPANALKELLENSLDAGSSNIQVVVKSGGMKLLQIQDDGTGIRKDDLPIVCERFTTSKLEKFEDLQRIGTYGFRGEALASISHVAHLTIITKTEDSQCAFRAEYSDGKLKLNTGFQNPKPCAGKQGTLIMAEDLFYNMETRRRALKSVAEEHNKIVEVVTKYAVHNARVGFSLKKFGETMTEMRTQSQSSVLDNIKLLYGAAIARELVEIRCEDKTTGFTLNGYVSNANYSTKKLTFLLFINHRLVDSSGLRKSIESVYYNYLPKGSHPFVYLSIDIDPRNVDVNVHPTKHEVTFLHEDMIITSITNSVENVLLGSNHSRTFFVQDDNQMGRSSVAAAPKNLVRTDPKMQKLDKFLNSTPDPDISILRSFNDSPSRVGVLDTSDFMKNSTVRSPSEAVTPNPNEIAGKEPIHKRREIRLRSVRNMRQKVEADSDKQLTTAFKNHTFVGCVDRSLALIQYELNLYICNTFKLSAELFYQKIIYDFANFGRITIEEPITIKELVMIAIEAGEPCGENKTSEDVAEAIQKLLVGKAKMLEDYFCVCIDQEGRLLAIPYILEGYFPSMEGLPTYIMNVARKVEWTNERACFETFCHQTSLFYAVQPGGSKENDELTSVMKFIIICRHYFILAYRTSTNGQSWKWTIEHVVYPEIKKCLLPPKIFAEDSTVAVLTSLPDLYKVFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N761</accession>
    <name>A0A1D2N761_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">V-type proton ATPase subunit H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05593</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit H is essential for V-ATPase activity, but not for the assembly of the complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000172">
        <property type="protein sequence ID" value="ODN01087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N761"/>
    <dbReference type="STRING" id="48709.A0A1D2N761"/>
    <dbReference type="OMA" id="FRWMTFQ"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000067">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.150:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="203"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN01087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="337" mass="39179" checksum="E8E22512FF09D19D" modified="2016-11-30" version="1">MLNRQDGFITNMTSRILAKMACWSRELMDGSDLHFYLTWLKDQLRIPENEYIQSVARCLQMMLRIDEYRYAFVAVDGISTLVSVLSGRHNFQIQYQLVFCLWVLTFNPTLSEKMNKFNAIPILADILSDSVKEKVTRIVVAVFRNLIEKPEDNQICKEHCIAMVQSKVLKHLDILQQRKFEDEDIQADITFLSEKLQESIVDLSSFDEYGTEVKSGRLEWSPVHRSEKFWRENAVRLTEKNYEILKILIHILESSKDPLVLSVACYDIGEFVRHYPRGKTIIEQLGGKQVVMALLSHQDSNVRYEALLSVQKLMVHNWEYLGKKLEQETKLPAKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7I2</accession>
    <name>A0A1D2N7I2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Magnesium-dependent phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000166">
        <property type="protein sequence ID" value="ODN01219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7I2"/>
    <dbReference type="STRING" id="48709.A0A1D2N7I2"/>
    <dbReference type="OrthoDB" id="2865258at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07501">
        <property type="entry name" value="HAD_MDP-1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010033">
        <property type="entry name" value="HAD_SF_ppase_IIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035679">
        <property type="entry name" value="MDP-1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01681">
        <property type="entry name" value="HAD-SF-IIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01685">
        <property type="entry name" value="MDP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01131">
        <property type="entry name" value="C1.5.2:_MDP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN01219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="29245" checksum="74870C2E1346D9F2" modified="2016-11-30" version="1">MSMPWSCTHLSLQVFRTLLPKAGSNSCWSGHGISPQFHMTTVSQLFQRFSTLHSGRYKVDPIVIDTHWRNKSRNRGSVINCSNNRNKSSSVSKMSGKGPGLIVFDLDCTLWPFHVDTTVNPPFVQQENSKVVDQNGETMTWYPEVPQVLEYLKSEGYPIAAASRTTKPPDAFKLLEFFGWTKYFSYKEIYPGSKITHFAKFVEQTKVPHNEMLFFDDEQRNIADMKNQGVKCVFVTNGVNMQLVKDSIQQFKEGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7T1</accession>
    <name>A0A1D2N7T1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S phase cyclin A-associated protein in the endoplasmic reticulum</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000159">
        <property type="protein sequence ID" value="ODN01333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7T1"/>
    <dbReference type="STRING" id="48709.A0A1D2N7T1"/>
    <dbReference type="OrthoDB" id="71500at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31434">
        <property type="entry name" value="S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31434:SF2">
        <property type="entry name" value="S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="843" mass="95176" checksum="8C8784614D71306C" modified="2016-11-30" version="1" fragment="single">LLQAKYNRYVELSERFEALNETTKKLVSEREELITKAEARLQRAAKNRKLHLQNIVRKAHDEEAKAKEIAFINLLEAQNKRHDYLTTAHEIEGRLQTIQEERRLKLEERACKAFSVIERQSRIRNNWQTKLERMQEKRRKAEERITREKEEKAKERSELAQEKARDREQRISALNSAKQAEKEELQKKIQQKQEDTARRHEENMEQIRQKAIELSVPRNQEDSAVPAIVRVCTLCKVSLPSEVQELAHLRGRAHMDAVRKAENLSSNTAVIESFGLKYVCDLTMDKIDFKIQVDKNRFKLLKKHCNKLMQRLIDGGMEYENLEKESSFSSPVPCDPDLKAKIHKNIKELDRLVSLFEKKKGTPTIATNMDRLMTEIRRNSVQKKSIKDVVISLGVVNVALRVVKCSASDLPDKLKTSACNLLVGVLYDSQPNSMYCLRGTAVCTLVECCAERLNILIPEGSRWVAGSAASPSEQIPYDPVLEALLELLFSIMNLVPDPFNGIGREGLLDRSTLFGVKNRTLDIIGYLVTSSVIDRFAIYCSAVRGPIEDQPGVADLLKMILDLLVVIVYALQFCWPGNGSNGKRDTDTTQLLAALESSELAGAVSMSYTLLLHQGAPTRPRMTPGIAETDIHTIPPPPGERTASIVRSTLLLINAVARVDHQALQNVLGSEAVSLQFRHIASQLLWQVVPHRSDPIARKLLNELLIAIAYFTVGNRHNQVTIQSGQTPTVLQQLCTLPHEFFNEISGIKVLFPTLISATYGCPENIEILVQNHIDLKALDAFMQSNHAAESDILKKLKITSLSKITDRIYSVDNRENEEPPKLNGNVECPTHMTNGHATDIKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N921</accession>
    <name>A0A1D2N921_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SOSS complex subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000140">
        <property type="protein sequence ID" value="ODN01752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N921"/>
    <dbReference type="STRING" id="48709.A0A1D2N921"/>
    <dbReference type="OMA" id="VMETQHM"/>
    <dbReference type="OrthoDB" id="419617at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070876">
        <property type="term" value="C:SOSS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031821">
        <property type="entry name" value="SOSSC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15925">
        <property type="entry name" value="SOSSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="131" mass="13581" checksum="94AD5B11C95ECD24" modified="2016-11-30" version="1">MSSEQRKVLEDIQRAKRLLKEGAAVSLGIHSPTTSTPPMLTTASPAFPSQAAAGIGDMMMSPGMRSAMQVLSQANLTSFGCFIPQDSHFGNSILPVLPRIEPVVPTTQNPPTGSSTSTITTTAIIGGGNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N934</accession>
    <name>A0A1D2N934_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Golgi SNAP receptor complex member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04924</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOSR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000140">
        <property type="protein sequence ID" value="ODN01754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N934"/>
    <dbReference type="STRING" id="48709.A0A1D2N934"/>
    <dbReference type="OMA" id="EILRDYC"/>
    <dbReference type="OrthoDB" id="422156at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048219">
        <property type="term" value="P:inter-Golgi cisterna vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="4"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="18512" checksum="A9C8A8577F3654ED" modified="2016-11-30" version="1">MIMYESLSEEIDVLLKRLTEVNEKMGEFPPQNSSFIHTLTRHRDILQDYTQEFRKTQNNLKSRKEREELLQGVKKEIDSSKTALNRRLDLYMKERDHLVSAAFKKIQSRMMDITSRFPTLNNLIHKINMKKRKDSIIIGCVIGICTFLLLYYGFHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N969</accession>
    <name>A0A1D2N969_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nuclear hormone receptor FTZ-F1 beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000145">
        <property type="protein sequence ID" value="ODN01635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N969"/>
    <dbReference type="STRING" id="48709.A0A1D2N969"/>
    <dbReference type="OrthoDB" id="5984981at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004879">
        <property type="term" value="F:nuclear receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06930">
        <property type="entry name" value="NR_LBD_F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.565.10">
        <property type="entry name" value="Retinoid X Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035500">
        <property type="entry name" value="NHR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016355">
        <property type="entry name" value="NR5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000536">
        <property type="entry name" value="Nucl_hrmn_rcpt_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001723">
        <property type="entry name" value="Nuclear_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24086:SF25">
        <property type="entry name" value="NUCLEAR HORMONE RECEPTOR FTZ-F1 BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24086">
        <property type="entry name" value="NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00104">
        <property type="entry name" value="Hormone_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00398">
        <property type="entry name" value="STRDHORMONER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00430">
        <property type="entry name" value="HOLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48508">
        <property type="entry name" value="Nuclear receptor ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51843">
        <property type="entry name" value="NR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NR LBD" evidence="5">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN01635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="209" mass="24279" checksum="32C5D2A03ACC0E1C" modified="2016-11-30" version="1">MLGWLEIVECESCWHLSADGDQDNDLGRSSSSNSNNQDYLQDLCAAADRRLYRLVKWCKSLPLFKNIQVRYFLNDDQTKLLLNSWCELLLFSCCYRSIPMPIGSIRINERLTLKESDAHGNQCITRMIHFTDNLRRLRLDTVEYAALKVIILMSSEVDELQEADKVRESQERLLQCLQAYTLARCPESPSKFGELLLKIPELQRICQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9Y4</accession>
    <name>A0A1D2N9Y4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000126">
        <property type="protein sequence ID" value="ODN02062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9Y4"/>
    <dbReference type="STRING" id="48709.A0A1D2N9Y4"/>
    <dbReference type="OrthoDB" id="5969272at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="76"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="242"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="343"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="560" mass="60878" checksum="E979C86CF5C4045C" modified="2016-11-30" version="1">MNIILDLVCLDGIKLPMTDRQSVSTNGTLIVEPVDRSDAGSYTCIAGNKQGSMSQRTVNVRVMGKSSFPLSCFVPPKITPFSFAADPHVGERASIQCVVVKGDLPLTITWLKDNYPIITNINSGSIILPTSSSSSPSSANGFFKLHQQPQHHQQPHDVNTHHRHYLMSTSLVGHNNHNSNGHEQTHAHNHNLRLSIRQLDHFSSVLSIPSLEPHHSGNYSCKVSNSAATSTYTTSLLVNVPPRISSFSFGDGLMEGMRTQVICTTTAGDEPLKLTWSKGGHVLESSTPDGNVGGGVHVSYFPPFSTILTIPNITASNTGNYSCQVSNLAGTAVHTAELIVTVPAKWVVEPADQSVYVGTHVAIHCQAEGFPKPAIRWKQAVGNLDKKEFREVGYRTPGVLSAENGTLIISRVTEDHEGHYMQIYKVDKTISIKTAPTATTTIDSPSSPQLYMQPPQPKHDPITHTSSFNPPSYINQHRTDRTHNTRHNPQGSPQTHRTQPHPTPHPHHHSHIDKGLSQAEPMHDTAAPPPPHPPQAPPAPNPATHRTATTPTPPPAPLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA09</accession>
    <name>A0A1D2NA09_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding cassette sub-family A member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA09"/>
    <dbReference type="STRING" id="48709.A0A1D2NA09"/>
    <dbReference type="OMA" id="WGIRRNP"/>
    <dbReference type="OrthoDB" id="8061355at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="293"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="625" mass="71777" checksum="833875B0781267B1" modified="2016-11-30" version="1" fragment="single">FKMIQRMAGMPSWVYWLCHGIGDIILYACVVQICFAIVYFFDYVSSSQFNFQEKAALWRIFMSWLCWAGIPYSYLVSQVINAPEAGYGYYILIHFCLGKCNQCKLFFVVFTSRHYSEDNHLPVFPPIYNQLWILLACDLYENITKSLWENDTTGTASTDELKYVEEKVDFSDSFRTCCKKYCELAGTCLNKTTANLVNILFETDEDATLPGLHHDMWALLLNGLVCWVLVILVEKQLIQNVYSFFSYKLCGNLEKAVASRDTKTSDEPEDVKDEHQKVDYMVEVEGDVDSEVYLVQDVTKFYKYTKGLDHVYFSVPRNAITGLLGLPKSGKTTIIEVLTSQCSPSAGSYLLQYLTGAQMMTIMGRIRGLTSSNCEEHVAWWLEEFGLKDVANFKCENYRKGQKRRLCCAMSLIGDCDMTIFDEPTVFMDSLEQYLFWNIVKRLPANKRTVLFSSIDAEEVQRQSSKVLVLDSGVLVAVGQLTDIFKNNKQGMFLLIRYGFQAYRKYTNFQKKAKLDKLRDHIIQYLSPCALTDEQENLLIYHLKDVNMKLSRVYAVMEGAKVRFSSLLEHFQVSEPSLDDIVLQFHKSRNKRRDKSIVPVAADDKVNTSDSQKIPTLASTVGQWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA33</accession>
    <name>A0A1D2NA33_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serpin B9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_04599</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000125">
        <property type="protein sequence ID" value="ODN02111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA33"/>
    <dbReference type="STRING" id="48709.A0A1D2NA33"/>
    <dbReference type="OMA" id="MTKGHIR"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19594">
        <property type="entry name" value="serpin_crustaceans_chelicerates_insects"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF278">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR 88EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905278" evidence="4">
        <location>
            <begin position="25"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="5">
        <location>
            <begin position="58"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="428" mass="48661" checksum="3383AAEDD847663C" modified="2016-11-30" version="1">MAAIKLTSVTAYLTLVLSISLVKGQCFKSDLVSEQPASEKATAEYQAVFYEQQLEFSLDMFHKLYNKENRTNLFFSPYSIHQALIMTYFGAGGETRKQLQTALHIKETDTKDELIRAFKMENFYQETRSENTTQYDLKVANRIFFSDEEPVRPCVQEIFSKEIELLNIVNETEKSREHINSWVEENTRGKIKDLIGSGHMDKETRIAIANAAYFKGSWEQQFKKSHTKLALFYVSQKEVTPTMMMYQKGSFRHGVSEELKAYIIELPYEGEAISMFILLPPFTPNALQDTISRLNASTLREAMDGMYPDSIEIFLPRFKIEQTFDLSQALRAVGVVDLFDEVAANLTDFSEKPGLAIGSARHKSYLEVSEQGSTAAAATALIGTRSGRPLDQTRFVCNHPFVFFIYDNALKNILFMGAFHTPKSAEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA37</accession>
    <name>A0A1D2NA37_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit Tim21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04830</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TIM21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000137">
        <property type="protein sequence ID" value="ODN01836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA37"/>
    <dbReference type="STRING" id="48709.A0A1D2NA37"/>
    <dbReference type="OMA" id="QISHIEF"/>
    <dbReference type="OrthoDB" id="436405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.320">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit Tim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013261">
        <property type="entry name" value="Tim21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038552">
        <property type="entry name" value="Tim21_IMS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032:SF6">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08294">
        <property type="entry name" value="TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN01836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="240" mass="26319" checksum="52FF0717B216D1A8" modified="2016-11-30" version="1">MVVPLQASALRTCFRCWGVSSPLGSSLLSQLVLKNGTFGSAQGIRYLSSSGRCVKESCGCCNKVGAVRFYSSAKPKPSSGRSLQQSSESSGGAVTLSTAEKVKENVKTVSYGGVILVGVVIGGAMLYFVLNELFSSESPNNIYTHTFKLCKLSTDVQDALGTPIKCYGEETRRGWRRHVAFQEFSGGETKFLRMKFYIEGPFKKGTVNLEKKTNDRGKYEYTYIIVDVDGYPSRRIEVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAH4</accession>
    <name>A0A1D2NAH4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fork head domain-containing protein crocodile</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04418</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000118">
        <property type="protein sequence ID" value="ODN02247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAH4"/>
    <dbReference type="STRING" id="48709.A0A1D2NAH4"/>
    <dbReference type="OMA" id="HTLFGDQ"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000016">
        <property type="entry name" value="Forkhead box protein I1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF388">
        <property type="entry name" value="FORK HEAD DOMAIN-CONTAINING PROTEIN L1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="8">
        <location>
            <begin position="67"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="67"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="248" mass="28936" checksum="2FA935985EA52E6F" modified="2016-11-30" version="1">MHTLFGDQNAYYRHPGSYSTALQPMAAGMSSAAYPYEQYSAMTRYSPYAAAHYPPQQTSQQSKDMVKPPYSYIALIAMSIQNAQDKKITLNGIYNFIMERFPYYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFDNGSYLRRRRRFKKKDAMREKEETIKRIQTISTTTQQQQQQLSAAQTAALTHSSHSIGSDHHHHHHQHHQHQSQHHQQHSHHRDASMTSKNVTGKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAR1</accession>
    <name>A0A1D2NAR1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dual specificity protein phosphatase 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000115">
        <property type="protein sequence ID" value="ODN02342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAR1"/>
    <dbReference type="STRING" id="48709.A0A1D2NAR1"/>
    <dbReference type="OMA" id="PAHYQYL"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000157">
        <property type="entry name" value="Protein-tyrosine phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057023">
        <property type="entry name" value="PTP-SAK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22784">
        <property type="entry name" value="PTP-SAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="128"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="203" mass="23793" checksum="6D81FACFA6AF6F98" modified="2016-11-30" version="1">MDVPDTYIEFLEANPAQRLPEWAIKKRSFLSPYLEKAGPIRAPWSFQWVIKRKLALMAWPQYPEHLRFLLKIGIRRLVCLTPESRPPIHMFTEFYYLEIPVEELTAPTMEQIHLFMCFCDQAKQFDEPVGVHDRVGRGRSGVFAACYLVRYCGLTAEMAIMQLRKTRPGAIDTKAQEKAVHDYYEELCRCPPDNACWQPEKYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCV4</accession>
    <name>A0A1D2NCV4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetyltransferase 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03603</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNAT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000087">
        <property type="protein sequence ID" value="ODN03080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCV4"/>
    <dbReference type="STRING" id="48709.A0A1D2NCV4"/>
    <dbReference type="OMA" id="VPYMSGH"/>
    <dbReference type="OrthoDB" id="5043642at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039135">
        <property type="entry name" value="NAT9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256:SF16">
        <property type="entry name" value="ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256">
        <property type="entry name" value="N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="19066" checksum="B425B3ABD207F92C" modified="2016-11-30" version="1">MRHDDNFKIVGNKVVLVPYRESHVPKYHEWMGDEETLRLTGSDRLTLDEEFEMQQKWAEDNDKCTFIILDEALWKASEGNEVEQSPYSIAEIEIMIAEKSARRKGLASEALTLIMTFGKEELGVQKFIAKIKEDNESSIALFQKLGFREVARSTVFHEVTLEKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE68</accession>
    <name>A0A1D2NE68_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="3">4.2.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Hydroxymethylbilane hydrolyase [cyclizing]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Uroporphyrinogen-III cosynthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_03422</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>hydroxymethylbilane = uroporphyrinogen III + H2O</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000080">
        <property type="protein sequence ID" value="ODN03266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE68"/>
    <dbReference type="STRING" id="48709.A0A1D2NE68"/>
    <dbReference type="OMA" id="DPYCQQL"/>
    <dbReference type="OrthoDB" id="5595751at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006785">
        <property type="term" value="P:heme B biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10090:FF:000003">
        <property type="entry name" value="uroporphyrinogen-III synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390">
        <property type="entry name" value="UROPORPHYRINOGEN III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390:SF0">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrapyrrole biosynthesis uroporphyrinogen III synthase" evidence="13">
        <location>
            <begin position="62"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN03266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="316" mass="34852" checksum="A360D3F7BC2F9276" modified="2016-11-30" version="1">MWRDKRLKVYLLKAAPETDQFPLLQQVVGNDKEQQPEETKAEGHASGAKSAGDVSEDRFITGLSLLEIEATLVPVLTFEYCNLSVLWQHLRNPAQHAGIILSSPRCVSSISEAVTACDSHNQWNANLLHEWSSKHIYCVGPSTIAKAKQLFSPSNVDSMIVTGQESHAESLGDTIIQDNSQCILTLPLLYPCGTLRRDVLQKKLANANIQCNQCIVYDSVVNPCLKLELEKVSHALKAISDCTAVLCFFSPSGVKYVFQQLDVNVLVNDLVHVVAIGPTTKSALEDYFSSKDISKVVLQCKDPTPESLIDILQFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEL7</accession>
    <name>A0A1D2NEL7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat-containing G-protein coupled receptor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEL7"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="139" mass="15905" checksum="70903D0E3BA177D0" modified="2016-11-30" version="1" fragment="single">WPTVQRIDSSNEGTVTIDCDDDAEEESIKRNPWSFIKGLDLSEENLNSKIIKLEIRYCPSVKDGWSNLFKKVNLTGENILRFSFVTDDRSNSTKPADIPPNFFENMPNIEILNLGKNKLITIPKLSTLKNLQSINLRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFB1</accession>
    <name>A0A1D2NFB1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3'-5' exoribonuclease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFB1"/>
    <dbReference type="STRING" id="48709.A0A1D2NFB1"/>
    <dbReference type="OrthoDB" id="448399at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051274">
        <property type="entry name" value="3-5_Exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044">
        <property type="entry name" value="3'-5' EXONUCLEASE ERI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044:SF61">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="282" mass="30905" checksum="93536F908FBC712D" modified="2016-11-30" version="1">MGMSCISQIPYPSYATRWVNIRTIFDRAYRYRIRWVSLKAVLDLFGIPFVGRAHNGLDDSANICTILQLLLKCGCNVYQTERILLQTEEQETNEQRILNDKSAGKYDLATVVPVRKECIYVYPSVYGYSLESHTSKSAMTMNAADYSQQSVASISSSSCESIASDCSNKENSIPTMYIPSKVSSESKNRASNGSKDTTITGSCGTPIVGGSSRRYNKKKKNSQLKNAGSASPSSCLKNGSKVGTELEADNSQLQSNKLDSHGSSLSHLQPLMVSELSTSRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGI8</accession>
    <name>A0A1D2NGI8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02326</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGI8"/>
    <dbReference type="STRING" id="48709.A0A1D2NGI8"/>
    <dbReference type="OMA" id="LTMEHEC"/>
    <dbReference type="OrthoDB" id="5577072at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="272" mass="32661" checksum="4352FD8EA0C9830F" modified="2016-11-30" version="1">MLRKLCSSLELKLYCRSATTVYSHAPTSTQFYRNPNCFQHNQAVIRGFQTSPQRHDLMEFFDVKKNWGETTIRSGRSWKLDELRIKSNSDLHKLWFILLKEKNMLLTMEEECKRETELFPSPERLDKVEESMENLETVVRERNRAFNLLETGETGEQPGTEEENFLGLQEYRQYNEHTVPKQENKPFLIAKRDEPKSSLKEKLWFITRFRRKQLFKRRQELRCHQYEVVQLLQKFPDLDVGALKEKYPDVNVDKYIERFWKEQAQGNLKSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH11</accession>
    <name>A0A1D2NH11_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02142</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000041">
        <property type="protein sequence ID" value="ODN04553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH11"/>
    <dbReference type="STRING" id="48709.A0A1D2NH11"/>
    <dbReference type="OMA" id="FXDTIFI"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="29111" checksum="D323434E78EEB14E" modified="2016-11-30" version="1">MDQRVTELVYNSKYPMNYTPNYLTLFEFEKFENHEEWRQWMFTNWHYSVYASVIYVALVFYGQWLMKDKSPMKLRKVLTLWNITLALFSAMGFFRSAPELFVSAIQPDGLHRSVCYLYHHMTVCIYCWFAHGAYDPSSRWFCTMNYMVHALMYSYYALRSLQIKLPRSFAMVLTFLQLSQMVVGLVVNFHSYFVLTNGEECARPMSNIYLALAMYFSYFLLFMDFFYKTYLTPSRSKAKAAKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHU8</accession>
    <name>A0A1D2NHU8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHU8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="443" mass="51111" checksum="93B735084878EA6B" modified="2016-11-30" version="1">METEDYILWVSVGLAALAIAALLFWFCLQKLNELWKTRKASEVPVYRQETVTTPPDLSRRRDVNINSSQIFPGGQFRESSTSTSRRANVYSSDNRRRDLESLTPQILPHQSTTNIPPRNEIIINVRSHYIYPTQDHLNVGGKDITIQIPPQPKAKKKPRKKPQAQREREDNITSQITAFQDNLRSDENPHETVEKVQKLLLSLENCSEDNGAQCNLIIGVDATPCTQAGYCVNLVDKTLKYYVLKKQHLPWNLHDEKDTAEFEMKNLIFALTVWKEIILKFKRIRVYTDNFAIVKPKDKYGGRAKRYLDHFVKCEKVTIINRGSLAVNRFKNLKYFAKYIQPADDLSRWQIDEAVDFLTRLYKIDKENVLGTHQKHPQRKRKHSSSLMTAELSPVSKTWYNPTENYKQLLDLADTVIECHLCGNSDCSSILTSSLRIKRSSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHW4</accession>
    <name>A0A1D2NHW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UNC93-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-93 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHW4"/>
    <dbReference type="STRING" id="48709.A0A1D2NHW4"/>
    <dbReference type="OMA" id="NGSHIAH"/>
    <dbReference type="OrthoDB" id="78663at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055120">
        <property type="term" value="C:striated muscle dense body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015459">
        <property type="term" value="F:potassium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006937">
        <property type="term" value="P:regulation of muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043266">
        <property type="term" value="P:regulation of potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051951">
        <property type="entry name" value="UNC-93_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444:SF13">
        <property type="entry name" value="PROTEIN UNC-93 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444">
        <property type="entry name" value="UNC-93 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="37194" checksum="CFA2C998733B6D13" modified="2016-11-30" version="1">MTVSNNAVSGNDLNLSSSTVASNRKLTIQSVSLAQLEKYSPNEPRRMQKNVYVASIGFLLLFTAFNSISNLQSSIHPENGLGTIGSSSIYAALILSSLLVPTYAIRKLTTKWTLVLSMVGYMFYMGAQFHPTFGTIIPTAILVGLCGAPLWASKSFYLTHVGNKYAEFVQDDAEVIIVRFFGIFFCLFQNSQIWGNLLSSLILSSGSSNWKPNETQIEKCGASFCPGDLYEIEDEEKSADLQRKINIFCGVCLALAFIAIGFTSIFLDSLDRYGEKERLEDDAVKMSTKRSLISTLRHMKKPYQLLLIPLTIFSGLEQSFFSADFTQKNTNFIIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIC0</accession>
    <name>A0A1D2NIC0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PDF receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01644</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN05013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIC0"/>
    <dbReference type="STRING" id="48709.A0A1D2NIC0"/>
    <dbReference type="OMA" id="EMFQKCT"/>
    <dbReference type="OrthoDB" id="5967113at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050332">
        <property type="entry name" value="GPCR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620:SF17">
        <property type="entry name" value="PDF RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620">
        <property type="entry name" value="PDF RECEPTOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="64"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="468"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="499"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="57855" checksum="66BC013963AEF609" modified="2016-11-30" version="1" fragment="single">FAFRICQANGMWGQHPDSNSTSESGWTNYLPCFNNYTIELTRRLMGSTNSTEESLRKVNIASYTRMVEMVGLVVSGLSLILALIIFGRFRNLWNNRTRIHKNLFIAMTIQVLVRIILYSDQHISNNLPYECYTLDRMEYTCESGYTILEYAKTAMFLWMFIEGLYLHNMITVAVFQEHLSLSVYYLIGWGVPIILTSIWTVMTENEFHGVCCWSGYNFSSTYFVLEGPRLVVIFLNLLFLLNIMRVLVTKLRESNSTEAQQVRKAVRAAIVLLPLLGITNFIQMVHSPIEKSPIQFAIWSYGTAFLSTFQGFFCSLIYCFLNGEVNDMLLKVQLQVRRYFRAHRHRKSAGPRRKSFAPGASMINHINTTLKKGDGGGCKQSASRLEMELQGKVNAKETEDGGRSIGKNDTNSHSKGGIDPFFEQWDEAELSSHNNVIIELVEVPHSAMQGNGRSHIGIAHSSSIDVQGKTVSSSGTSTGVLNASVADVPNKSKSNDNVSHAKDHMVNSENDSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIQ8</accession>
    <name>A0A1D2NIQ8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_01840</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIQ8"/>
    <dbReference type="STRING" id="48709.A0A1D2NIQ8"/>
    <dbReference type="OMA" id="LQNFCDD"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10324">
        <property type="entry name" value="SLC6sbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00754">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN04846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="550" mass="60667" checksum="5164063342D78EF7" modified="2016-11-30" version="1">MSSGYENKGFEASSELPPPAYDQQSIPMSEIGLPAPVEQTKEEKSGDAESQGGGAFLIPYLTVLVLIGRPIYFLELTLGQFSGYSQVKCWKCAPFFKGVGYGSMIATMAVLTYYVSIMALTVYYFIASFQKNLPWANCDEKWAGEGNCNGTGSATTQSVPEMFFLREVIKESANIDNGVGTPDWKLSLCLLFSWILIFGTLIRGVHSSGKVAYFTAIFPYFVMIILLVRGLTLDGSWKGIEYFVKPQWDKLAEPGVWYAAVSQCFFSLNTGFGSIIMFSSYNPFNHNIYRDAWIVSFMDTFTSLLAGFTIFAVLGSLAEELGVDVKDVVQGGAGLAFVSYPDAVAKFTWAPQLFAVLFFLMMFTLGLGSAVSDAGAIITIFCDSFPKLVRWHVTIVVCFVGAAVGIVYTTPGGQFMVDLVDFFGGSFVIYTTSVLEVIGIAWIYGVYNYLDDIEFMLGFRLGWYWKICWGILIPIFLTIILVYSLVEDISPSHNELPYPVIALVFGWGLAAVALLAFPLSDSRLCLKNSWDLSSLIRAGDPEILRSVWNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ02</accession>
    <name>A0A1D2NJ02_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000027">
        <property type="protein sequence ID" value="ODN05258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ02"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ02"/>
    <dbReference type="OrthoDB" id="8251779at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="819" mass="87628" checksum="DF1101757A9B3FA2" modified="2016-11-30" version="1">MSIPANFAHLQQSPVMLPGGHKMVPIKLVTLPKQTGGQLQTIPIGNATSNRSSPNLLEAVNIVANAGSRSSSPKTTLIGNSVQSTPLNLSSMSLPVGSNLHFVPISVSSASGTTGNVKVLMTQPIKMQQAGIPQSMVVKSVLMGNQPTTIRVIRPANRQDPISIQTLIKQPEQQPKKDILRPKSDIPATIAASAASMVVKNEFTVQTEPLFKKLDGVEIVDTGSPLNNDELPFEADIIHDEKDLADVLAAEAKNEIIPVENCTNFHVGIKTSSNVNPSTTKVSSGSAGVSSMNAGTSSTVVHNHVSTTKKVPNSNKEELPTPDSPVAVMRVTSPLFTYSAKVSNSRSSVSRSPIPLEPDGPDLHGEDPEIINSFLRSSTNSRLHVKSTTTNNSTDTKITSSDVLPDHTYNMSAGMNCNANNIEQELSIEIPPMELEGTGLSPSQNPPEEKRCTRSTRSNTRLSPDITAFMSDTPKPTKLSAKPDSLSLKNSPKPSPTGSLKVLSPTPSSLTITPSTSTRSSPILHNQHQVNASNAAATINAVALGIIDKIQGNSTGSNAKNSRLLKQSGANKRKRQESDSSSASRDENIEEKAEIDLNSRPGKRKCSENAAEMIKVCIGVEDSPKRNVSTVKKTDETKVKETKGKRTMATVAEDDDDVDSEKSFPRGRSERSSRESSEDRSSSRGSSAQRIVSSEKSKPGKEEEVQKELKTSRLNSRTGKDSVAKSKNQSGRVSPHQSSTPAKKAKLSGKVTAKRPNRPNSKDKSPLTPAKTRTNVRKDIVTSQAAVEKNATTTPSANPENENARRKTRSSAAGKRHAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJB0</accession>
    <name>A0A1D2NJB0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000024">
        <property type="protein sequence ID" value="ODN05344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJB0"/>
    <dbReference type="STRING" id="48709.A0A1D2NJB0"/>
    <dbReference type="OMA" id="GWPEDYD"/>
    <dbReference type="OrthoDB" id="206708at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916:SF3">
        <property type="entry name" value="UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="365" mass="41966" checksum="1CC91D1CB987E09B" modified="2016-11-30" version="1">MLVSIALPVYNAQEFLDECFESILKQNRSTDDQGQASKINDTEEKTETVFSVEVSVYDDGSTDSSPSLIDKWAKTFGSTQGFSFRLSKNDTGSPKGVGFARNETIRQSTGDYICFCDADDIMDPNRISAQLKLNMLHPEAIIGSKFRRLPADSTRSFTCWANSLTERQLQTQIYMTFGPTIVMPTWFCHRRVYDRVEGGFNESGKGTPEDLIFFYKHLDQNGKVARVDQELVIYRYHSSATTFSVTDEIIRNIRLERMESKVLNSWNKFSIWNAGKLGRRFYRSLSPQTRQKVTCLCDVDKKKITQKWYHPHPIKEKVSIVHVKDASPPFVICVKTEITWDPTGDFRMLLDSLNLEEGVDYYYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKB4</accession>
    <name>A0A1D2NKB4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_00981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKB4"/>
    <dbReference type="STRING" id="48709.A0A1D2NKB4"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963:SF39">
        <property type="entry name" value="DUMPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963">
        <property type="entry name" value="ENDOGLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905679" description="EGF-like domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="42"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="548"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="619"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="688" mass="73967" checksum="A92AED2D151F9255" modified="2016-11-30" version="1">MRLPLITVITTILLLLLSSKNGFALPQGSTSSSSSATSSTDPCENSPCGKGAECKSMGSIAICVCPEDGKGDPFIACMKEEAPVTVDQNDTDQQSLASSTSSIVAAASSLPASSRSSDSTSSLTSLSSSSSSTPLNMNHFVTSFDIGSAPSSAHQARTAATSSVTVTTEHPPTTTSSTTVTTERGPISSASTTTTHSPYIFYQSSIRPATISSSNHNNHNNHNNHNYQYQPESHRIPIISSAETNHYPNHDTNSYQHRYPPMPITSSPYGSSSPNIFNEKTFAPLADFGMTNSYSYSHRGQTGHLSGSGSHNAYEYDSRPIAGTPSYNILGVSSSSPERYGQHSFHPASSGFPGPITESPTSRYPVSDSPSYNNGGSSSSSSSSGYHHHHHSPVRNDLSSHNDNFNRISDPLGKYESCRMVNGVVVCADNSNRGGESGFIHGETTSSYGFHSSRDRDQFSSYYPIPSSSTRYPSSSSMRPTFDYNYVNRRNGYPQHYEERQPLDNERTSYYPFPKEQRISTQSIHTISSSSSSSHLPVSSRNDNDHHLCKSMCGINSICRLVLERPVCGCPEGHTGDPSVRCDPNIQESNRGSQGQGYCQRHVDCRENEVCANSKCIDPCKEQDQMSTTSSVLTGEFSSSGSSSSSSARGQYTGSLCGSNAQCLVVGHTPLCKCNNGYFGNPYVSCVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKK2</accession>
    <name>A0A1D2NKK2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">Acylphosphatase</fullName>
            <ecNumber evidence="2 5 6">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_00935</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5 6">
            <text>an acyl phosphate + H2O = a carboxylate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="2 5 6"/>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKK2"/>
    <dbReference type="STRING" id="48709.A0A1D2NKK2"/>
    <dbReference type="OMA" id="NSRDSIC"/>
    <dbReference type="OrthoDB" id="7961613at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000011">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10029">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10029:SF3">
        <property type="entry name" value="ACYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="Acylphosphatase/BLUF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905680" description="Acylphosphatase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Acylphosphatase-like" evidence="9">
        <location>
            <begin position="54"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="147" mass="16496" checksum="DAFA180D73413270" modified="2016-11-30" version="1">MNQQKRLVCVIIVVSVVAFTYLRATADDSEESEESEENLPVPTTRMSGSQELVYVDFEVFGSVQGVFFRKYTQAQGNKLGLRGFCRNTSAGTVSGSMEGPRPEIEQMKHWLQNTGSPMSRISRAVFKNEKVIEAYSFPKVFDIARTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKS0</accession>
    <name>A0A1D2NKS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKS0"/>
    <dbReference type="STRING" id="48709.A0A1D2NKS0"/>
    <dbReference type="OMA" id="HTFGLKY"/>
    <dbReference type="OrthoDB" id="110174at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026620">
        <property type="entry name" value="TMEM177"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21824">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21824:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="37454" checksum="67B1736223F68931" modified="2016-11-30" version="1">MSTSEKPTPYMAKKAKATPPPSYWTTNHGRNVIGVVAAVGGAVYFGGHTVLHTFFLDKYRDAMQLYKHGFPTPLSPATLTRCRSVVADLNVKLKTPDSVGFFCVLGMDMFHAGSLKLRGGSIVGVPRHFSYEAQEQIERNDIMVENKPVEWGSDGAQLLKDSLILSERAQKFAIAREIVMTNNHAPYIHGGLGASAIFAYFCTTRTLNEKLYGLARPKSFRVFMYSLVGSFAFGLWATATDILTKRYERKADERVGGMGIEYAKGGVEFYAKTLERNMALRSLMGPKGEKMFTFYGNDVEFIRQQHIPYTERKRNLEVIAENLSKVNVAEENPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLN3</accession>
    <name>A0A1D2NLN3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hemicentin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_00535</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLN3"/>
    <dbReference type="OMA" id="QWNINGI"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905725" evidence="4">
        <location>
            <begin position="24"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="557"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN06119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="664" mass="74290" checksum="2D93D5049A51CB82" modified="2016-11-30" version="1">MKKSVSLRIVSLLLTFVLHDALSVITARASETNPKIVFTHVGNIWNNVSNGSSNAVYYSTSGSDLFVSCTAPYPIQWNINGIIAPAEIVKMLPPKRNLHENMFEIRTNYFFLSGNGYAGLAASAQIACEKVGDDTIRDYFSVFVRGNNPFVEPATKIVTDSKLIPCPTTDPTSPTMLYLQASDGTEGLVNDVTYNPIEGFRSDNVFDGIYICKKESSHITIVANASQALPDHQFSPTVELIKSFSDEPIEFTCSSKTKSIKLKLEDDTTVALTYSVDTDQTKTAKLSLPEGLKEKNVKGKVTCMSNDKNELIKEWSYEFIEAPELYLDNFEGEVDCLSPLTPKMAQTVRCRNSMDCQFMDHCFQNETLCNFKKQKQFFATDDTFCWIEKLATGRACASVPYSHLNGRVQCTVLGLTKKYDFFISLDSIDVNSTWKDAPEKELLRMDATPEILYTESSSRFFCTGSAYLFADSLSFEIEYKNGTKRLLQDDGKVVNISNPYSENLRKIDEFNVLGVLNINLPIDAIAIHCLAPWWNSTDIMTTSSKFETRQLLAPTIPEVNENEVKVTLYINAPNQRLTCFAKGEPQPKYQWLFRNDTKSAYANVEDVFPSLTTILGSNGKSYLEFPSVSEMNSGEFKCAANNSLGNVSQIYQVQVSDKKNPCLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN41</accession>
    <name>A0A1D2NN41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YLP motif-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NN41"/>
    <dbReference type="STRING" id="48709.A0A1D2NN41"/>
    <dbReference type="OMA" id="PPRIVIF"/>
    <dbReference type="OrthoDB" id="513595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032204">
        <property type="term" value="P:regulation of telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026314">
        <property type="entry name" value="YLP_motif_con_p1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13413">
        <property type="entry name" value="YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13413:SF0">
        <property type="entry name" value="YLP MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="606" mass="70170" checksum="518628143EBB0F5A" modified="2016-11-30" version="1" fragment="single">PHGYDEPGYHDEFSHGYPPYPDTIGSRGRGRGYPSGPWGRGHPRGYPPGHHMYGRGPPIHDPHYAEYGSAPPRGRPYARGMPIGRGGPEPQWYHHDDRSPIPPNHPTVTPPVVELSPSPEPVPAIKIAPPNPEFDRERRRSRSRERVPRGREERSRSRSRERSRRGGDSSAEKRDRRRESSPYSSRRDRERDKRSSPDRRSKNDDKRDSRDRDRARHYRDRRGRSKTSNPPPPRYQTVLIEDILNMPGRSKRPPRIVIFMRGLPGAGKSYCVGLIKERESQMGGKAPRILSLDNYFMTELEKKEKDPGTGVEVKTTVMQYDYDEEREPLYRAQLIRQFRKTLDEGFFSFVIVDCVNEYARHLEEMSSFATQKRFQRTKEEILKISKSWERTPSHLIKLDTRTLLQDEAVQDVEMEDVSDVETDNNTEKALTPAERGKIGPQVDELEDIEDEDSGDHLLVSSVASKWDTIEQSQEKLNKLDGLVKKRRTNDEDTQAESGRSIEDWLTSNTSEEYVQTRETRPGQKRVRWADIEERREQERMREMGFVVGHTDWKRMMDPTFGSSALTKTKYFVKVYNDSYYVGPKRGLEGTDGVAPDLELVELNHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1A5</accession>
    <name>A0A1D2M1A5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Homeobox protein Nkx-6.2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007385">
        <property type="protein sequence ID" value="ODM86748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1A5"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF35">
        <property type="entry name" value="HGTX, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="15212" checksum="88EED05BFCA35843" modified="2016-11-30" version="1" fragment="single">VFKGVGGGGSNSDTDGKKKHTCPTFSDNKIFALENTFEQPKYLAGPERAKWAIEMTESQVKANSNVTPAFPFSSADKIPLILWDNNPEWPFDITVDPDSEDWSSDVYVNEYWEDDNDKLSTSSFYLCIKFIKGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1C4</accession>
    <name>A0A1D2M1C4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19913</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Putative variant histone H3 which may replace conventional H3 in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007314">
        <property type="protein sequence ID" value="ODM86769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1C4"/>
    <dbReference type="STRING" id="48709.A0A1D2M1C4"/>
    <dbReference type="OMA" id="THRFKPG"/>
    <dbReference type="OrthoDB" id="7942823at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000001">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="7">
        <location>
            <begin position="44"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00059206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM86769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="16259" checksum="9D40187BCE450F63" modified="2016-11-30" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLGQTYPWRTCLISSNKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2E4</accession>
    <name>A0A1D2M2E4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone H2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006072">
        <property type="protein sequence ID" value="ODM87138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2E4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="80" mass="8843" checksum="5876AA2716B1018B" modified="2016-11-30" version="1">MSGRGKGGKVKGKAKSRSSRAGLQFPWVVSIVSSEREITLSELELELQSTSLPLWSTWPLSSRVGRLSSSPRKRKEICLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M340</accession>
    <name>A0A1D2M340_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Histone-lysine N-methyltransferase eggless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_19328</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005505">
        <property type="protein sequence ID" value="ODM87354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M340"/>
    <dbReference type="STRING" id="48709.A0A1D2M340"/>
    <dbReference type="OrthoDB" id="616263at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046974">
        <property type="term" value="F:histone H3K9 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070828">
        <property type="term" value="P:heterochromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051516">
        <property type="entry name" value="SETDB_methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041291">
        <property type="entry name" value="TUDOR_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46024:SF1">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18359">
        <property type="entry name" value="Tudor_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00391">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MBD" evidence="12">
        <location>
            <begin position="320"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="508"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="11">
        <location>
            <begin position="662"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM87354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="678" mass="76773" checksum="446B56E62E374C27" modified="2016-11-30" version="1">MRNPPTPSNGKRKFDLTNVELDLREGSSADTRKQVSKVKNDKKIIARTSFSLQRMQNTGPSGGEKIYAMGRTLLSCWHEAVVITPAENEHEWVVKYNPDPKYRKPCQLPGRKQKGRNFFIRTLNWTQMAYKKPSPSTLPVGTRVIAKLTGFAENDGQIYAGVVGDVPKPNNKNRYLIFVDNKMVQYVESCDVYRVFYQSNPVWLDVHEISTGFTENYLSKYPDRSLVHLQLGSLVPVKKNGKWQIALVLEIDGVIARVRFENEMEITNVLRSSEMIATVMNPVTKLNLIGPDILPEYQGSIRPHECNSGFVESYVSKTKLKRLSPLAIPLFFSWSRSVTEPKVIYGAPCGKAISSFKELIAYLQTTKSNFPQELFSFDVDISVSDQFVPGRSLYKNDVSKSSNTLEDIISYLNFFKLFIFQDASHGLEPTPIQVVNSIDRERLLEFEYIVESVLSQKFKCLKKNESDIQMCCKCVDSCKVKNFLVVRRHFCSCKRNCPTRVVQNGVIWPLQIFKSSKKGWGIRTIFNMPKGSYICSYAGEILCDDAFKRASRAHSSIYMASSSQVSTGKEELVASIKKKRLVTSALPQAPPKDCFTVNATFKGNVARFFNHSCDPNLFMQRVFHKTHDPRFPNLAFFTSSRVTAGSELTFNYGYVVGSDPANRIDCHCGTSHCIGRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M347</accession>
    <name>A0A1D2M347_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-acyltransferase WSD1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005417">
        <property type="protein sequence ID" value="ODM87393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M347"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="29088" checksum="5D35989DFB97EE50" modified="2016-11-30" version="1">MTLKGIISADEMRTLFVKTVLEKRQPQNPKLLQFPELKQYQTKHLGFLFYRNDPNFKIENYIHEDISQKDDPDFRSLETILENVSYRPYPRKGVHGKCSWCQIFKDPKFQPNSEPTTLLVLRIHHTQIDGYSLLNVLVKGLAQKATRAIEGRNPKAVGKVFQRLTQPIPINLVKKVAHRYNVRVPAVLMALVGQNLTKIFEKSEKSSKNCICFIWSTNAESSWKAYKPRKSRDDDDFPFKTKYCGPDEGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-03-27" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M472</accession>
    <name>A0A1D2M472_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Epidermal growth factor receptor substrate 15-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004718">
        <property type="protein sequence ID" value="ODM87770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M472"/>
    <dbReference type="STRING" id="48709.A0A1D2M472"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="116" mass="13018" checksum="B1D7AC516343362C" modified="2016-11-30" version="1">MIETLQNNVKEVGAKASNTEAKLNDAMKRLNEAERTRDEARKQYNALKQEFDQVVQQLQAAGAAAAAGGGASDEEVRKTREEMARVQGEMERLLQLVKMGQDEVNNKERTIKQLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4E3</accession>
    <name>A0A1D2M4E3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CUB and sushi domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004554">
        <property type="protein sequence ID" value="ODM87847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4E3"/>
    <dbReference type="OrthoDB" id="8248739at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251:SF30">
        <property type="entry name" value="MEMBRANE FRIZZLED-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="98"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="41"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="28511" checksum="7E9B6DB1806552FA" modified="2016-11-30" version="1">MSLYLMPTINQQSMQVANMMSLSNETSRTVKLLQYAHGQDKVALIQQISNLTMLIEKLQRERSEDRARTRTELSLLQAKIVDLEKSSGPQWAEQTVGCGGVLIANSGLISYKFRQLYMNDERCVWTVRVNTRSKINLQLLEDGFQNQSNSDFLTVTEFGEADDQHPVTLLTSTRLEHGSKALHTFQGPVIFITFYSDSSIPGTGFTLRFDGVGNITDSFNINAIRHINLHQTFPTGKFTYPSEENGPHISQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4F4</accession>
    <name>A0A1D2M4F4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004682">
        <property type="protein sequence ID" value="ODM87791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4F4"/>
    <dbReference type="OrthoDB" id="8251650at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="107" mass="12014" checksum="AB09BBCF53B5AD6A" modified="2016-11-30" version="1">MYSVTYTLQFNVKIFLEIDQPVIIKGEAPIYIATTRDDIETLRLTEEMSNLDIPHVEAGRRGSEASLISRASGRSAKSLPPAYSQLSLRTPSWETLPPSYDELEPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M607</accession>
    <name>A0A1D2M607_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_18274</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003628">
        <property type="protein sequence ID" value="ODM88409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M607"/>
    <dbReference type="STRING" id="48709.A0A1D2M607"/>
    <dbReference type="OrthoDB" id="1707433at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-T/Histone H4 histone fold" evidence="12">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF15511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="70" mass="7724" checksum="415B5A757EB18648" modified="2016-11-30" version="1">MTGRGKGGKGLGKGGAKRHRKVRLVESKYLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M712</accession>
    <name>A0A1D2M712_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003232">
        <property type="protein sequence ID" value="ODM88758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M712"/>
    <dbReference type="STRING" id="48709.A0A1D2M712"/>
    <dbReference type="OMA" id="KTHECFK"/>
    <dbReference type="OrthoDB" id="6629909at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33053">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33053:SF24">
        <property type="entry name" value="TRANSPOSASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="713"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="738" mass="84604" checksum="13BA4C3968474836" modified="2016-11-30" version="1" fragment="single">MRKIVIGRRRIQQLAKQDATSFLQRNIQPKDPIPKKQEASNNGNISDAIEINEVNWSFEETRYPQVESSIELKNVEDCKSEDLSLISQLRQWAVSSAVNHKQFSSLLKLLKTHECFKDFPSDSRTVLAIQKVPEIVNLHPGEYVHFGLTELIQPCINSNIKSLPLQINVDGLPLFKSSGKDLWPVLGQFVGINTEPFVIGAFCGRKKPTSVNDFLAPFVNEFNELKASLSKNNINLFIHSIVCDAPAKAYIKCIKGHTGYFGCDKCNVEGTHISNRMAFTNLDATRRDNESFRHRRDIEHHLADTVLENILDLDMVECFPMDYMHLICLGVMRKLLNIWMKGKPGEHKISGQQINALSEKLISLSGETASEFARKPRSQFVFCAVNSYIVNFIRMHSLLKYFVEGFQTLYGSELVSYNVHGLIHLATDSQKLGVLETFSAFKFENKLQQIKKYVRTPNKPLQQIVHRILESGSNVCKLKSDIKRNWNLSQPHECGPVIDLFNGKQYILLDLNDFQSNEVFLLGSVYSKKYPVFLEPCNSTILDIYYFDKVHSEQIVRLTVSDLKYYKMYFIMEIKDEGGETCEIIPESWFFPEEEECAWPPVKNVSKYVEKKRSPEANWKRYPARKIHVYDTYKAARENLHRAEMTSDLNSEVDETPKRKRRIASRNICYTQKTDDSDIDSRQKVTKLKTVPSLPVSIPVSSVEIARLKNRRTVQNPPQHGSQLGSSPMNFSTLENIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7X5</accession>
    <name>A0A1D2M7X5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002942">
        <property type="protein sequence ID" value="ODM89059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7X5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="262" mass="30011" checksum="419C15E659FD8283" modified="2016-11-30" version="1" fragment="single">TEPVWGCFNKEKEKRPATHTLLLVKAWRPGESRKACKKFPLPFTPHFFSGLIPTARLKTSPFIKMLPNPCPLYNSPVGREGGSYSSALLHYFEKIPLKSLLLRGLPRNFTSHSYCQPHSQHDFSWVDIVLYWVPKSVINSILKLYGDYGTTYVEILVVGVIGLIHGIAITIYVMFVVYAFIIQLRNRPDPQLNPHIKFQPWLNPRAPFMRWKRVLTILLNNQLPDGISAFEPTPTSAPLYSYMHGIHGLTYKHIDYTCCLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M984</accession>
    <name>A0A1D2M984_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein AMN1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002553">
        <property type="protein sequence ID" value="ODM89546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M984"/>
    <dbReference type="OrthoDB" id="10257471at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="31777" checksum="BCECF005EDA95232" modified="2016-11-30" version="1">MRSVSHDNYDLMRRRHQFQLESSVELGTLQQLAVSVIVTAYKDHREEWIKSMPCIPKKIRQEICKRLMYKGDLDNELFSLCVDVDRNVWDLRTIRGNFTSESCAVLSQCKSLELLRLSYPSCSSAALTNMLKNFTQLRLLEVTNTEEMNDSVIEAVASSCPHLEVLNVKGTAVTNQGMLTIANLQLKLSELDISRTNISREGVDFLKSGPMKETLKLLRFNRCEMLGSAKTIRDIVLSFSNLKDYSFDFIEGEDEAEINDALNQLPGPTPGQNVFFNIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9B0</accession>
    <name>A0A1D2M9B0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-type lectin domain family 17, member A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002563">
        <property type="protein sequence ID" value="ODM89529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9B0"/>
    <dbReference type="STRING" id="48709.A0A1D2M9B0"/>
    <dbReference type="OMA" id="GYTIIPF"/>
    <dbReference type="OrthoDB" id="7760957at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051004">
        <property type="entry name" value="DC-SIGN_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22802:SF465">
        <property type="entry name" value="AT17652P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22802">
        <property type="entry name" value="C-TYPE LECTIN SUPERFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="11"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="146"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="323"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="586" mass="66804" checksum="FCDD69CA16368BEF" modified="2016-11-30" version="1" fragment="single">ESRHFRKLGTVEGKTYFEDVTLRSWNASRAFCEKRGLEFGTITSRAEANFLQSSHIYSGWYWVAGKDLQDDGRFSWVTTGEAANAFRFGNWWHSEDNEHCLVYDPPSRFFKRACYHGHYTLCETFDQIQTKSNQSGKAGLINLGAIDGWSYYGDTIPRDWDDAKEYCEDNEMKLATIRGKSQVDFLKEACREIEYDGWYWISGMKLEDGTKYETWHTEDRCPSFGLLDEHYYQHHCYHKHFVLCESVVEITSSTHEQISSTTQPANTDEISVVLATSSKADRETEGLSELTAAVIGTEQSVFAVRKQMQINSLAESGAVLGAIDEKVYFGDAVLRNWTQALKYCEKHGMRLGTITNQAQVNLLKSAFNSISFNGLYWIAGKDVGGDGIFTWIHNGESVETFDNLGWEILNNEDELDLHCLAYSADDNESWNYFRGECSEKIFTLCETIPSIPNKSIVTTILVVIVTTILFTLAIILLLPKAIEWIRARWLVNRQVPIDLSIEIGLHNVLLTAYKTYCKMARSLYLVQIVLQVFIVLGLTNGQNNEASYFTNGLSDSQFTNEDNDVFIFLKLLVLLENNDSDNKKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9W9</accession>
    <name>A0A1D2M9W9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Charged multivesicular body protein 2a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002446">
        <property type="protein sequence ID" value="ODM89684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9W9"/>
    <dbReference type="STRING" id="48709.A0A1D2M9W9"/>
    <dbReference type="OMA" id="KENQMSA"/>
    <dbReference type="OrthoDB" id="10252926at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="221" mass="24987" checksum="D8B17640112E67BE" modified="2016-11-30" version="1">MEWLFGRRLTPEESLRKNKRALDKAVRDLDRERSRMELQEKKIIADIKKTAKAGQMETVKIMAKDLLRTRAHIKKFLLMRANIQAVAMKVQTLSSQNAMTEAIRGVTKAMQSMNKQLNLPQITKILQEFEKQSEIMDTKEEMMSEVVDDALGGDNDEEESEAVVAQVLDELGLQIGDQLAALPTAQGRLETPGRNQRELVAAAVSDVDADLQARLDNLRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA78</accession>
    <name>A0A1D2MA78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Trypsin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16888</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002357">
        <property type="protein sequence ID" value="ODM89794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA78"/>
    <dbReference type="STRING" id="48709.A0A1D2MA78"/>
    <dbReference type="OrthoDB" id="10059102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000047">
        <property type="entry name" value="Trypsin eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF83">
        <property type="entry name" value="COMPLEMENT FACTOR I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903692" evidence="7">
        <location>
            <begin position="18"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="32"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM89794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="273" mass="30099" checksum="CC728E1E7B44F004" modified="2016-11-30" version="1">MKHFVFVFILCAGSSHQFQELPQIKENEDKFIIGGSPSTEGELPYQILLQNQGRYVCGGSFVNVTGVHFVLTAAHCVNSRYPTRYTVIAGEHDRTHVSGHEQKRAVTKIFVHEKYSSRTIQNDIALLVLDEPFEVNEFVSPIPLPTQGQKTKGEVMVSGWGYTSPMRRFGSTSKVLKKVTISVIDNLACKAFYGVHFIYVSNSMLCVGKLRGFSSSCFGDSGGPLRSVEGGYVAGIVSWGTICAFPLQPGVYTEVSRYVNWIELKASSVGLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAF6</accession>
    <name>A0A1D2MAF6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002302">
        <property type="protein sequence ID" value="ODM89902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAF6"/>
    <dbReference type="OrthoDB" id="10023921at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="62" mass="7415" checksum="A4A0D9B98CDE6E0C" modified="2016-11-30" version="1">MLRESDSDLGFATRCNFPGVAFFRTVFRVRSLLDDIWELEAKISRKRGWVTPYNIRHNYSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEE3</accession>
    <name>A0A1D2MEE3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trace amine-associated receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001571">
        <property type="protein sequence ID" value="ODM91386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEE3"/>
    <dbReference type="STRING" id="48709.A0A1D2MEE3"/>
    <dbReference type="OrthoDB" id="6022667at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="190" mass="21133" checksum="4C0E9616D43F5CBE" modified="2016-11-30" version="1">MMITVLFFIPNRHQILSDDMQSGIFFFGMSNSLFNPLIYGIFHLWKPRRKELQRGISSRRTLLTNLSFERRRSSNGTILNGSIGNNNRLGNGATVHGKHGSLLTTTHSTAGTISMAGGGTLKKHCLDENHHDSHNHRNLQQQPHHHLNVMPSAGGVGFISFFQEARGLTANRIPQPVAFASVVIRMVMVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEG7</accession>
    <name>A0A1D2MEG7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative phosphatidate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15278</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001558">
        <property type="protein sequence ID" value="ODM91408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEG7"/>
    <dbReference type="STRING" id="48709.A0A1D2MEG7"/>
    <dbReference type="OMA" id="KIMSICK"/>
    <dbReference type="OrthoDB" id="8907274at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF103">
        <property type="entry name" value="PHOSPHOLIPID PHOSPHATASE HOMOLOG 1.2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903891" evidence="7">
        <location>
            <begin position="20"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="95"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="330" mass="37048" checksum="B6A4CBCA3DEA3D2B" modified="2016-11-30" version="1">MAAALLSLFLLNVINPTIPALRCDGTRLLDPSISHKFRGDTVTVSKLLSVTLLFPLVQIFITEWFYNRDKRNLYIYGPPESSRWRRTLIHTSRWYRDYFFGIVFMLFLNDIAKTSVNSPRPHWIDSCKPNFTAEACNLGWVDEYNCTNNDISNWKLADARKSFPSGHSALGFFTAIFMTMYQHRRIRKQSLGPVVLVWLHTMWIGWAIFCALSRVADNRHHPIDIAFGGFIGAIGGIFTATVLCGGFGKPMKAAGYQNKVVSGMNGSATIVDGFPSNGNTTTVALPPGTNGGVRHNHHDNKRPSLRRLLSTQSTMTQMSEIAEDRELDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEN2</accession>
    <name>A0A1D2MEN2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Longitudinals lacking protein, isoform G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15373</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001596">
        <property type="protein sequence ID" value="ODM91311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEN2"/>
    <dbReference type="OrthoDB" id="6418787at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016199">
        <property type="term" value="P:axon midline choice point recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008406">
        <property type="term" value="P:gonad development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035167">
        <property type="term" value="P:larval lymph gland hemopoiesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007526">
        <property type="term" value="P:larval somatic muscle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045476">
        <property type="term" value="P:nurse cell apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007464">
        <property type="term" value="P:R3/R4 cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045467">
        <property type="term" value="P:R7 cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF111">
        <property type="entry name" value="LONGITUDINALS LACKING PROTEIN, ISOFORMS F_I_K_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0221">Differentiation</keyword>
    <keyword evidence="4" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="8">
        <location>
            <begin position="30"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="439" mass="47406" checksum="9B47C7C99C9C8078" modified="2016-11-30" version="1">MEDQFNVRWNDHTAVVIQSIVEKLERDVLTDVGLTCEGRTLKCHRLILAACSTYFDKVLSEFSAPNLVIFINNMKFWELEALVNFMYRGEVTVSQEKLGDLCKAADQLKIKGLAKNVDATTSGIGPAVKDHLDNSTNGFDMVDLLHYGNGSDANPRAVSGGQHHKSLLRPKSNLPTTRKLQKVIMKEQQESPRFVKVAKLERSSQGSGTLQLPLMPVKMSSPTACHLRSEAAGGSNDGSLVGVVSQLPQNGVANSIFILNNEGAFSYFGGTSTAEKNSQNQEVKKEETEPPGTTSLRTAAIPAELKTAKTSVGTSIPAGQSSPSTTSSASAMESVDKKQRLEQAAMHVASSNKSVKQVALEYDIPRTTLCAYMKRNGISAYQLVSTNDTCTEAGSGDQNFLTDHGGQEKNDGAILLGTNGSVEKNERESKFDGITIDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFJ7</accession>
    <name>A0A1D2MFJ7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001427">
        <property type="protein sequence ID" value="ODM91768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFJ7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903950" description="CCHC-type domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="37441" checksum="78224C6CAC1B28FE" modified="2016-11-30" version="1">MKSLTVTLLSTLLDLFGGQIQTDTTTMANRSIHKFGGNAAFPYPAFGTKRQRDLNPPSLASPQFDPMNIFRKSIAFLRDRDADSPAPKMRKKELPKIKIEPGLIRIKSEKELLGTSSISSDSDLDDEGEIKSEPYASSPPSSGSSNCRSTINSYRKTTSRSPKWRSFGADVKFTSTPSSSSRRQNQVAPNGSVSPPPFCFHCKRFGHEKQVCNSSWHYWWPQEMLDRHPWIRRKVRELRKVHLNKHPQYLRFAMNLDRAVEVAEKRKMNQERKSYGKPWHSGSPAPMSPRGRTLFKPNDCHIFSHLYIKSSTFMENEDIVLFMNSYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGV8</accession>
    <name>A0A1D2MGV8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001286">
        <property type="protein sequence ID" value="ODM92246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGV8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17929" checksum="A4F1DD7B104A569A" modified="2016-11-30" version="1">MGARPSKHVEPPPTQDIVKEAITEDDNALRQQPQLTSELWQIILKDVEPEEFKILMDNCPQYKKELSSLAPSFLFPLLIRVLVKNGFLVENPLPILTYRLINSKVKAVIDSSLNGSPPPWLTDAFTFSDSTKIDEFIQISSRRTTYRSVLPFPTSKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGY4</accession>
    <name>A0A1D2MGY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001307">
        <property type="protein sequence ID" value="ODM92171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGY4"/>
    <dbReference type="STRING" id="48709.A0A1D2MGY4"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00696">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904015" evidence="1">
        <location>
            <begin position="23"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="194"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="37472" checksum="800AC1CCE2BD67FD" modified="2016-11-30" version="1">MILKSVVLLSAVIAAFIFLVEAKTLTTKEGQKIQWIPSGDARKNMSQLIPAGEDTNGKINYVARGTLSRHDSRWVPGKAHMNGNVFYMYYAFNGSEFLTQTFELLVVPLESTTWVQGEGQTIPRLAIVGGLEPSNVETSYICRGKVDNLTMTGKLLKSSGKCGIPFHKEQRLDDYEVLVINEFGESIGLSNSELYQRNAVDIHNEFRETHHVGPLTLNDDLNNRAVLCAEYYATKGTIDHRCPYKNGAGENLWASCCSPPTPENAASGASRGWYSEVSRYNYTCNCMSNAGHFTQMVWKNSREFGMGVVTVGRYTAGCALYYPPGNYVGDYLNNVLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH05</accession>
    <name>A0A1D2MH05_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">limulus clotting factor C</fullName>
            <ecNumber evidence="9">3.4.21.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_14476</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Selective cleavage of 103-Arg-|-Ser-104 and 124-Ile-|-Ile-125 bonds in Limulus clotting factor B to form activated factor B. Cleavage of -Pro-Arg-|-Xaa- bonds in synthetic substrates.</text>
            <dbReference type="EC" id="3.4.21.84"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.84" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01001296">
        <property type="protein sequence ID" value="ODM92213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH05"/>
    <dbReference type="STRING" id="48709.A0A1D2MH05"/>
    <dbReference type="OrthoDB" id="10002959at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042381">
        <property type="term" value="P:hemolymph coagulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000120">
        <property type="entry name" value="Putative serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0353">Hemolymph clotting</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="CUB" evidence="13">
        <location>
            <begin position="58"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="14">
        <location>
            <begin position="202"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="13">
        <location>
            <begin position="502"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00052079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM92213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="686" mass="74963" checksum="7E4B43AA25217770" modified="2016-11-30" version="1" fragment="single">KPALPIIQSQSFNPKCRLKLSENYHKRLTSCHGFLGKQALALSFILLFAGVATASLDCGETVQLKADSDDSEFETLPHNIPSEGSCKWEILGGENCEVELSCTINLPESDDCSDASLLVSDGAGGQQRFCGQSEIPNLRASEGLRDLFLLLQGSDDFTGEGDISCSAKCAAPATDGVERLHQNFERKTVGCVCGLRNDDDRIVGGEDAKFNEFPWQAAIVKPGTRIPFCGGTLINSRYILTATHCFWFAKKKASDMEVLLHAHLLDMHRLKGAKDVELGEKGSTRGPGWDEAKKSDDDENTLRFEVEEVIMHPLFTKLYDYDFALLRLKGKVDIADSDSPTPICLPPVNTLDSFNLDGKQLTVSGWGLADENAKGSTRLLQKLDVPYISSSQCSSFYKNLITERMMCSGFEDGEQDACTGDSGGPLIHQVESKQWWQMGVVSFGEGCARAGKPGVYAKVTEMNQWISFNTAQDDIMGIFQDKVVVVVLIGVFSTLTTVNGQCGKAFLIEDSKSASFKHGVNADLSCKWELLGTRTCEIEVTCKVDLPKDQDCGDNYLLITDGFAGAKKSCGSETFSLKASTGLRDLFLVLMTSDDVDTSFKGIECTAKCSKAGSTTTHLAKDWSRKVDNRCVCGLRNEDDRIVGGVDARFNEFPWLAAIVNKGTRQPFCGGALINDRFILTAVRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHC6</accession>
    <name>A0A1D2MHC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger protein-likewith KRAB and SCAN domains 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001247">
        <property type="protein sequence ID" value="ODM92386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHC6"/>
    <dbReference type="OrthoDB" id="3168046at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="520" mass="58593" checksum="EECB70703815AD3A" modified="2016-11-30" version="1">MSPRQDDISEETPPHREVGVSTQDAEPTITISPKEEVHDHDDDDSPVPNEKQNAMSQTLMRASRADDGHSSATTLTAEAPGPSLTPAVTPPTLKKAKSTKNSPLKKNLPSTSRNGALPAVGGDSLKRTRSSATSRCNMMPSIVLHPLDAELLMKMKKESLATAFQAEQDSYEWESDDEDLFTVTTKKKRQLFEGVEILRCVNPAKKEYLQCSVCSFTLQITKKYVKGNTPYQKMKAHINYCHKNNGVANMTEQPPAIFECDFCAETFATRESFREHQQLNPEHQIPAQECDICHRPLKFSSTCNTNLLRHKFSHKNDEERRAALEAGERGAYYAFLQKIDEKITLPNKKRRISHFSQKNKTARHVVTKKTVADNIKSRFGHFECHLCNRSFPLKNGLALHIKAHMKKINMEKSKLPSPPSSCTDVEVLKVKRIKKKNGKYESPPVLFPVSPQKKRKTIKTATQSSPKDTEPSKVVVRAEEDAENPEPTSTEMPQQQEADNDVVLPILKREVVEERIETDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHD0</accession>
    <name>A0A1D2MHD0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2-22 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001235">
        <property type="protein sequence ID" value="ODM92418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHD0"/>
    <dbReference type="STRING" id="48709.A0A1D2MHD0"/>
    <dbReference type="OMA" id="THSFTID"/>
    <dbReference type="OrthoDB" id="9993688at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000021">
        <property type="entry name" value="Putative ubiquitin-conjugating enzyme e2 k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="90"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="285" mass="31963" checksum="629E2021438264D2" modified="2016-11-30" version="1">MQSMHSNLLSSEEVQAKGHFQVVPYGALRLLEAPVPWFHNDDVTNVCQGKPSIQLLLVTTVSSFSHHLFAPCTHSFTIDVLSMAMAVANIAAQRIKREIREIMKDDEVERCGVKVQVNEQNWLDLKGEINGPPDTPYAGGHFNLEILIPETYPFSPPKIKFLTKIWHPNISSVTGAVCVDILKDQWAAAMTLRTVLLSLQSLMAAPEPDDPQDAIVATQFKDYHDDFLVTAQHWTGIYAGGPNINEEFETMVKTIERMGIDEKIARARLSQANWDYNRAVSLCFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHM2</accession>
    <name>A0A1D2MHM2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14262</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001235">
        <property type="protein sequence ID" value="ODM92421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHM2"/>
    <dbReference type="STRING" id="48709.A0A1D2MHM2"/>
    <dbReference type="OMA" id="MCENLIL"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050260">
        <property type="entry name" value="FAD-bd_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429:SF2">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="21"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="314"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-rubredoxin oxidoreductase C-terminal" evidence="9">
        <location>
            <begin position="480"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM92421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="546" mass="60693" checksum="59E0F6C4AAB0EC77" modified="2016-11-30" version="1" fragment="single">APVSCRAKMETEENAPEHYTFAVIGGGIAGVSCVEQILEFDPDASILLISSSPVVKVATQVTRLSKTLEDFIVLEKSLKSFKDVHQSVRVVHGVVAELLPEQHLVVTKDGEKFHYKKICICTGASPKVLFPGWEHVVGIRDTESVAELAKRISKAKKVLLLGNGGIATEFVHEVSGVDIVWAIKDKSISAHFVDPGAAEFFIQSKLSNTNQTKDSSLPTTTKQTSCDQGSSFPENEAVHSTDSGSEVSVTSAQAQDIDIENETKKISPSKRRKYTISSISAEPQTRSQDDNSFGSALGPDWHQNVNLRGQNLMKNVEILYEKECVGIRKTGSETEEWPILADLNDRTIIGCDLVISATGVLPNCTLFEYCEQEPEKGIFIDSAMKTSVPDVYAAGDVCFSKWSWSKHWFQMKLWTQARQMGLYAGKSMFLTVRNELDPEDATEIDLDFCFECFSHVTRFFGFKVVLLGLFNGQGLDKSKQHLLIRCTKNLEYIKLVFEDWRLQGAILIGDTGLEETFENLILNQVDLSSYGEDLLNPDVDIEDYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ55</accession>
    <name>A0A1D2MJ55_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GTP-binding protein Di-Ras2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13614</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the small GTPase superfamily. RasD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001082">
        <property type="protein sequence ID" value="ODM93068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ55"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ55"/>
    <dbReference type="OMA" id="TEAPGEC"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000475">
        <property type="entry name" value="GTP-binding protein Rhes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052236">
        <property type="entry name" value="Small_GTPase_RasD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46149:SF7">
        <property type="entry name" value="GTP-BINDING PROTEIN DI-RAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46149">
        <property type="entry name" value="MIP08469P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="196"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="32309" checksum="9575BA8613875205" modified="2016-11-30" version="1">MGDVERIRLVVLGGPKVGKSAIVKRFLFGSFMEKYKPTVEDLYSKEYDFGRITLKVDFLDSAGDLQFPAMRRLSIATAHAFLLVYAIDDVSSFETVKGCFQEIQEQRADFQEVPIVVAGNKMDVELTSVEVEFDDVSDWLSSHLPTLKTKIMECSAKRDANVREVFRSFIHLSKIPLQQQLEAEASCGLKRRLSAHAGSKSAQSRSNCASPMNSKPTTPTTPQCRTSGFSTPTKTPASPSSLSPNYLTTEDANSPFGRNKPRSRSLIRRCSKKVKKQVQDATEAPGECHMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJD5</accession>
    <name>A0A1D2MJD5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">[histone H3]-lysine(27) N-trimethyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.356</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13772</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60292"/>
            <dbReference type="Rhea" id="RHEA-COMP:15535"/>
            <dbReference type="Rhea" id="RHEA-COMP:15548"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.356"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.356" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01001119">
        <property type="protein sequence ID" value="ODM92914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJD5"/>
    <dbReference type="STRING" id="48709.A0A1D2MJD5"/>
    <dbReference type="OMA" id="NCEVKRM"/>
    <dbReference type="OrthoDB" id="6141102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035098">
        <property type="term" value="C:ESC/E(Z) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140951">
        <property type="term" value="F:histone H3K27 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10519">
        <property type="entry name" value="SET_EZH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000001">
        <property type="entry name" value="Putative histone-lysine N-methyltransferase EZH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026489">
        <property type="entry name" value="CXC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045318">
        <property type="entry name" value="EZH1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048358">
        <property type="entry name" value="EZH1/2_MCSS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041355">
        <property type="entry name" value="Pre-SET_CXC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033467">
        <property type="entry name" value="Tesmin/TSO1-like_CXC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21358">
        <property type="entry name" value="Ezh2_MCSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18264">
        <property type="entry name" value="preSET_CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01114">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51633">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CXC" evidence="10">
        <location>
            <begin position="680"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="794"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM92914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="916" mass="103097" checksum="851B78814528CF73" modified="2016-11-30" version="1">MSMRPRRTSEIGRLVVVKSPIGSSISLASKLLRQNRAKMAATSSASSSSSLPSSPQPQRLARLRRLTTTKNEPVGASVGGTGGGTNTPIKSASSPEKQSKSSKGQLLQLTPTQMMIRKLYERINRAHKASQRESVKQMWRENRENLDSIMKQHHRLQTQRASSISCSVVGADDIEEATMKIYSNRSTTSEKIKVLVVPEIADELCSLGVAQDGREYQCIPVTTLSHVSQIPPVLDWTAIPHNLHEDDGKFLTNIPFLGDEFIDKDAKFIDEMVTLYEGKVHEAKDSSSFKKMDDEVLYTLIQALMKIETDEGPNVFDDVAGIECQGEGDEKQEQERFEKVESGVTKDIDAKECEEDLQKTTFSAIAAKLLQSENESVEPGKPSETDDEPITVKAEIVEEENKEAEKVIRTSGTPEAMEVDSENSDQSTGLLVVPTKPVCKVARPSNTILSLISQTFKGLGTENEIRERYDNAEKVRGTPQLPILPNGMELHTSESYSIPNVEGPCAKYLPKEATMHAFRILFCRRCFIYDCKRHTGDDQVDVKYYKNNQTPSVPTSISASSFTTGFNFLCKNPDCWQMNDTVERTADEILREWTPGDRSLFLCFIESFPFNYCFVAYLMRNKTCLQVKEYANLENVPKMESCPSVSSRKPKHRKPRMGFNKKSCNPNNKRNVTRRWINNVKKTEKAKEEGGIKSGGKLPPRYMPCLHEKGGECDSSCTCRINKTSCEKFCTCALTCPYRFPGCRCTSTCDSKRCICFAAARECDPDLCLGCGANEDELEKISCHNVNIQRKLHKHLLMGRSDISGWGIYIKNDAQKGEFIAEYRGELISHDESERRGHVYDKIQHTFLFELNDHFVVDATRKGNKSRFVNSSKNPNCEVKRMLVNGDHRIGIYAKRYIEAGEELFYDYEDGNCNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJS2</accession>
    <name>A0A1D2MJS2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001042">
        <property type="protein sequence ID" value="ODM93233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJS2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="43379" checksum="7FC7D599A9B29F9F" modified="2016-11-30" version="1">MAALAEEFFKNLSTKKRDQLLSGLATIGVNNKEPEENVSRKRKRSGQSLLSNTSTSASSSTTCQSSFDDDVIVLSSDSEEEAKDAAAAEDDEGEVDQDVDTSLTDSHLGDSPTSVNDYDKKDPVISFAKRYVEEKKAKRALRAAAKEQNGVSGPPVNNNLEMYEIQLNHARPRFLRSNPIAKIAIQAHKLNVENNYDINRLGRFSKTKKKVTVPVPVPTAKKVGKPKQSRAPPTASLKRQLSDGSDVECTNNNPKKKRIRYKYITSSSSSSEDKSDSEDKDYQPTKNKSRVIGVENESTTSDSNDDQLPQSSRSRQKKDKRQIREITRQLVPALIVRVCQQCNYVWETEVDLRTHRDAMHPNVPLSALFAVIEIKEKRRCRIKRSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK63</accession>
    <name>A0A1D2MK63_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Solute carrier family 25 member 47-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_13224</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000980">
        <property type="protein sequence ID" value="ODM93456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK63"/>
    <dbReference type="STRING" id="48709.A0A1D2MK63"/>
    <dbReference type="OMA" id="CTEGIFN"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF10">
        <property type="entry name" value="SLC (SOLUTE CARRIER) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904162" evidence="11">
        <location>
            <begin position="21"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="93"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM93456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="18647" checksum="747C44B83FEB5606" modified="2016-11-30" version="1">MLLGFLLCGCVGGAAQLVVACPVDLVKVQLQSLIHKAEMKGPVDCIVKIVNAKGIFGLYKGLIPQAWRDIPSSGLYFAIYEFLKRQLSFGQEPTKFAQFMAGGIAGTLSWWSIIPLDVIKSRIQGESGEKSKYKGILHCGSVIVKTHGVKGLFHGFWPLSIRAFPLMVPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLQ4</accession>
    <name>A0A1D2MLQ4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000878">
        <property type="protein sequence ID" value="ODM93976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLQ4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="32"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="52633" checksum="CD50EBDAE08D1D63" modified="2016-11-30" version="1">MRRSQRLKDMAARRTVPEPGVTSAVPGEWNYLPPEVMQEKVLKKLNARNDLLKCRQVCSAWKVVVDKTLEKEALSLWTEWFSFDGRLQTQPPHIPKMDLLPTTRSFTWNHSSLPSTRNLRLGSPFPTNSMKITMHRNATAFEKREAMVKQLSVNYGQYLTSFVLSKFRVDFKFLSGILGPLINLKALTLQKVAPMHELVPLKNRCMSLRKGSLGHRKLPPLPNLAYLKIFDCVKRVSDLFIYSYSEQLVHLEAGLWSKPCCRPVKFTNLKRLKLSADFHTQMRIFPEVEPSLFPSLEYYSEIHLNQPYGWDELLRAIENLPKTLLHLNLHLLNSDIDKFSSKEFKPESLTSIFPLLKTLAIPFPRNTGQAERIRRWLLAKFPNLETVHLLNYTYEKWFSSVDHSHRFCVDVNREVIHQLITSAGFWTECKKLKKIILHMECQPMSFLELVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMI3</accession>
    <name>A0A1D2MMI3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000864">
        <property type="protein sequence ID" value="ODM94081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMI3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="76" mass="8512" checksum="EFBB5A3DF3D1290B" modified="2016-11-30" version="1">MDNIDFEVTDTFAKKMSKGIPSLSKLKLKRSQGKKKPPVPPAKLARPVPTRLTHSARLPPEVPFGMQRFKPTTTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMZ3</accession>
    <name>A0A1D2MMZ3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-pyruvoyltetrahydropterin synthase</fullName>
            <ecNumber evidence="4">4.2.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_12480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.12" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000843">
        <property type="protein sequence ID" value="ODM94204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMZ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MMZ3"/>
    <dbReference type="OMA" id="YETERNF"/>
    <dbReference type="OrthoDB" id="14045at2759"/>
    <dbReference type="UniPathway" id="UPA00849">
        <property type="reaction ID" value="UER00819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003874">
        <property type="term" value="F:6-pyruvoyltetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00470">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.10:FF:000003">
        <property type="entry name" value="6-pyruvoyl tetrahydrobiopterin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="entry name" value="6-pyruvoyl tetrahydropterin synthase/QueD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589:SF7">
        <property type="entry name" value="6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="16753" checksum="ACD1D3CB8D1285FA" modified="2016-11-30" version="1">MSSRPVAYLTRRECFSACHRLYSEQLSDKENYEIYSKCANPNGHGHNYVVEVTVRGRVDPITGMVMNIQDLKVIMDKAIMQTMDHKSIDKDVPFFANSKIVTTTENVAVFAWDQLKLHMADPSLLHEIKIWETEKNIVVYRGEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPC4</accession>
    <name>A0A1D2MPC4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000737">
        <property type="protein sequence ID" value="ODM94863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MPC4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34660">
        <property type="entry name" value="MYB-LIKE PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34660:SF3">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="652"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="922"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1086"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1337"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1444"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1670"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1844"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1920"/>
            <end position="1952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2064"/>
            <end position="2163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2182"/>
            <end position="2206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2398"/>
            <end position="2444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2773"/>
            <end position="2811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="941"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1338"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1368"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1381"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1461"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1474"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1852"/>
            <end position="1863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1872"/>
            <end position="1882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1884"/>
            <end position="1893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2064"/>
            <end position="2075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2079"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2114"/>
            <end position="2128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2421"/>
            <end position="2435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2780"/>
            <end position="2800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2821" mass="320539" checksum="B067DA5F59F7A6A7" modified="2016-11-30" version="1">MILQWAMTLSVLQIDVLCITIETVPLFVNKQNAKRNVYDGFSTMKFAFFSLLVVIFILGITCNVEDQTQPPLAVQEEAKLHDARIKRQDLNEADEDGNQDEADDCDPEKQALSQCHNEDDEEEEEFENEEEKEKHERKFHHHYVSKWHVGKRRVVERKSGKRPMGRTVDNGALQPEKGALGKVAGSAGASKGGPPDPASAATGNSTASTKTSTRKPMTILGGRNKTNSNSIFGNIGRSNGNNSPKTTTTLPTTTTKAPPKTASSNKNVAKGLPSHNNRAKPTSHVEEEPIDFKDVDEDELFTYVEPKILGKDASCSDITKDSNWEDQILIRSCHYITHDHPRQQYRPRWGPSKADRLNKAKFKHLALFNIRHDLDFQEAGDRCSVRLQNEFMHLGGEAGQPPSPISLEVMSFNRVWYKRLCSFFSYLECIPSNQVRQIVKQTAVANQSYDVPLHFNDSGKDTTGLLRLKIGGRGPGKARHKSGPGGGRLDPRAFQGLAAMQEEVDYPLDGVCVCSTRDPKYPNRMVSGYGMDFVEDEARPRWCVAAPGNLCGRVYFRRALWPGQQHYEFSDHIGCPRRYNGEEYECVRWARDPTIKTNRSDFPDALTSTCEKKPEDLELIRETLLAEEKAKRDNKRRRRKMSDAPGFRVDTYSLILLIVVAIYMLLCLSFFFEIATLKSTRLFAMKLKIVFFFVVALLSMITYPANGQSSTKASTKKSPKKSHKHGIFDGSHPGNSSKGRLKFPSKHHHLQPSSNKRTNSDSGALKVAGPPNPRILLKFLRENQKLQPQPPPLQRRHLHSAYKEAAPLPEDAPCSAATKDSAWVDQVKIRPCHYETDTQPRQQARKKWEPQKNSADEENYNLFHHLAIFNIKYDLDFQEAGQPCKYFAPVDLEVMSYNRVWYKKVCSFFSYLECVPRIERRRKHKQRSKKEKHKRRKRDDYLEDDDDDNYEDLDEDDDIFGYGNEDDDDANVNEDDDDANDDDDDSTADDDESFPDPDSGFPDPDDDNGFPDLDDDNNIVADAKNDNNVATDLKTENNVGTVAKIDNNVGHKKVKKPGRKHKSHRLPPMNFQDSGLDTTGLLRLKIGGRGPGKARHKSGPGGGRLDPRAFKGISKIQKDGYKYDGVCVCSYRDPDFPKRLRTDYGMDFVEDEARPRWCVAAPGNLCGRVYFRRNLWPGQMNYEFSDHIGCPKKYKGEEYECVRWAKDTTITTTKTNRTHFPTSQTSTCEKKPKNVELERQTKIHRKKLKAKKRSSLAPTFRKDIILLPLLITVIVKTVAKAKSSQILSMKLISILLVASLVIVIISQCSAKNGHASTTASTKKLRKKSRKKQILDVMSSNANSNSTSPANTTSNTEHNNHDAQSLQHHTVHHSKWAKKNVHHSEKPVHNEIETVIQGRGIFDTIKGKSKSGADPKGRGIFDLMEKKKNDKGADASGRGMLSRAGLSSLIGKKQGPVIKTQTKPKPRGKKGSNNKNEKLSESEEKDPSAPAVLSEDAACELLTSESEWEDQIPIRPCHFKNYTHPRQMLRPKWDLTNENDTEDKEMFHHLALFNIKHDLDFQEAGDECSVELQTQFMFEGVDVTDDDRDNETAFAKLKEPVDIEVLSYNRVWYKRLCSFFSYLECIPKEEVRVRQKQFYATTRKPQGAQDDDFTPLHFNDSGRDTTGLLRLKIGGRGPGKARHKSGPGGGRLDHRAFKGMSEMQKDEIYTLNGICVCSQTDPKYPNRKRPDYGMDFVEDEARPRWCVAAPGNLCGRVFFKRNLWPGQVNFEFSDHIGCPRKYNGEEYECVRWDQDITIQTNRTEFPDSFTSTCEKKPKDPELELHASAIVFLLLVVLLIMVKPPTNGQSSTKASRKLNRQSHKKGILDKSHSIYKTPTVSSKAPSKKEDKEQHAMHQNNSFHPLRLPIRMMKKHRQRISPTLPAKNVGPQGRRLLTSSSQEKANKPGIQGRVPIRPCHYVSHTHPRQQPRKKIVDQHPDPVIGKDFREEFRYLALFNIKHDVDFQEAGDPCSVELQQQFMFGGYLMEDREPINIESMSYNRIWYRRLCSFFSYLECVPKDEVRRKEKKRGKKRRRSKRDDDEEEDDDDEEGEEEDDDESGDVEKQDETNEFLMDNTDDGVEEDDVESNDNGESNRGEGGENVEDGDNPPSAAQQQAKNSGKKKYDGLITYKDSGMDTTGLLRLKIGGRGPGKGRHKKGPGSGRLDARAFKSKSDLPDEGYEYNGVCVCSSYDPKYPKRKRVEYDMDFVEDEARPRWCVAAPGNLCGRVYFKENIWPGQFEYTFSDHIGCPKKYDGEEYECIRWTQDTTIKINRTKFPTSRTSTCERKRKDPELEREIKLQQERARKEKKRGKSSGPIIMINIAIIAPSNAIDSQSTSYPGKSRRTTISDAVRSYLTNDTLSANTKHKNAQGGTQHQSKFAKRKGEPQSTREDDLPAKAKGKKSKSLFDFSNKDVTETSHSNLGILNSNKDKGNKLNQAGRFISKKKSTTPKAARTTVTTTPRQLLRLRHPKQIVLDASCDEVTKDSAWIDQTKIRPCHLVSHQHPRQQLRKKLIEDPTWGDQDRYMFNHLALFNIKHDLDFQEAGDECSVLLQQEFMFEGVTFDEDDPDNCNLPPMIFDGGFTPLHFNDSGLDTTGLIRLKIGGRGPGKARHKSGPGGRLDHRAFQGMSEMQIDERLPRDGICVCSSYDPKYPERLRTDYGMDFVEDEARPRWCVAAPGNLCGRVYFKRGIWPGQRHYEFSDHIGCPKRYNGEAYECVRWAQDTAIKTNRTKFPNSQTSTCEKKLKDPVPEGQSQKEAELTKKHKKKKSDAAVSAYVPYRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPU6</accession>
    <name>A0A1D2MPU6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000733">
        <property type="protein sequence ID" value="ODM94922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPU6"/>
    <dbReference type="OMA" id="FGIVRIC"/>
    <dbReference type="OrthoDB" id="10538793at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="241" mass="27304" checksum="69DE92AA74BA50BE" modified="2016-11-30" version="1">MTSSCETLNTKQLSRIGSSNSSGGGGRGSSIRTSPTCHHHHPSTRTMTERWFLCSQTARTEARLLAILDLISSIVYLIMFGLLTFAIIHHPELVRKYLDEVPENQDIARLLTYGTAKQAFFLSILILRPATSLIIAFMLFVGAQKRSFGIVRICFFVSIIYITVDMILFIPKTIYTQNGKIYVITYIFNVIYMLYELWVMYELKKEVQEYRDKEKEDAEPETEDTTVVGEGESAGTGEDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQG2</accession>
    <name>A0A1D2MQG2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000706">
        <property type="protein sequence ID" value="ODM95142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQG2"/>
    <dbReference type="OMA" id="NHISTHR"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="4"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="541" mass="60784" checksum="C501DFBA02A731B3" modified="2016-11-30" version="1">MEIVASNLPVQDLLRCRLVCKLWASEMAQYLTKRKALVVAYEDCSEAKELVKKKQDGKFVNISTLCVLEIPITSQIIVDVVKNFGETLSGLKLDDCNPDAKDLYSILIGLPCLEVLSFKQTGTRRVEETEETPSTLDGLTSQNQALRMTCLKKLIWEEMQPVKYFERIIQMFPCLEDLELLCWSKPDPVRVEGLRLDSLKHLSITCDNNFSEQHFQALAKLKLKLKKLSLHDVKPGGRKKMRGLKLFLESVSKTLVEMNLNGNGRIIANLRPNTFVTQATPFPIDFPGLKTLNIDCSLMADLKMLNHIPKLKKLECKFQDWKGWWHLLNAKGVPQVHAKVEEMSLGAIDSGCLGKIADCFTSVTKLYVSEDRIDDVAFRVIAKQMQQLTHLRITTSTNRDAKKLKLTDSGFTGISLEDCQKLSSAAPETIDRDYIDRIRINPSIGSLKGLYSLELACSEIFITDIAVLYGIAELKRVSTITLPKCKLTNASLEVLGDLPSLLVLELHKSCGVTPEGVASLRTKKKDLIFNLYSDLNSRIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQH1</accession>
    <name>A0A1D2MQH1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MOB kinase activator-like 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000683">
        <property type="protein sequence ID" value="ODM95350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQH1"/>
    <dbReference type="STRING" id="48709.A0A1D2MQH1"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="38" mass="4439" checksum="02756F5A6C6A2CAA" modified="2016-11-30" version="1">MALHGFLEFFQKEKTFRPKKKFEPGTLRYGLHKAAQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRD8</accession>
    <name>A0A1D2MRD8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000638">
        <property type="protein sequence ID" value="ODM95669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRD8"/>
    <dbReference type="OrthoDB" id="8272841at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904434" evidence="1">
        <location>
            <begin position="25"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="13849" checksum="74FE11B74961BDB6" modified="2016-11-30" version="1">MFKTVIFVASSCLIASLLVTETTAEFGKGLFICRNGTMAPSEGLTDKLKNAMTRNALLSVLLRLLEGQRSLINLVKTEFPEAQQANALERAEKCFEDRTFDKEDKTCSSIAEFSVCGTKLVVETTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS26</accession>
    <name>A0A1D2MS26_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000658">
        <property type="protein sequence ID" value="ODM95525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS26"/>
    <dbReference type="STRING" id="48709.A0A1D2MS26"/>
    <dbReference type="OrthoDB" id="5950777at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="489" mass="55919" checksum="6F9B9CA0537FB4A9" modified="2016-11-30" version="1">MTTKVVRCKTLNLKPFSLMICWFEIEAYPSHITSSPSVIASRQHANNERLIERIAESYPVRRAAQLTVYLFQRSKSIMEDTGAKDKAVKFKHRFSDELKKEWEKARGGNTVSYPGMSYLSFHWPMCLPELGDGLIVVSPKNETLPKIMYIEEKLCTNLCMDEEDDDDTSAVSFQGSLKKSTPESKRFVNHLECNNCKNSMKDKYAHQRSYMHEARKTSDKKKLKQKVWNRMSDYIVVKAKKNNFEKSSNYTTDASSDEYELCRKNLSGKKMSATSSTSLLKVALAMIFISLVLTNVYLQREIYGLRKAVKCLEGKFQGYDSNKGMLPLLSVFNPKASEIDPDIPLSHDNFNLLMFMTSWSESMIESFVQMKEGVSTWIDEMWIGIVASESNSSHPSSIHRPCSLSWSDEIIEWLASITTTVDDDMWTGVQISVNSQHPNQLSDSGCADPIKESTSSWSDEIIQWINQTTKEVTTWVEDVWTQMFESVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUB0</accession>
    <name>A0A1D2MUB0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000521">
        <property type="protein sequence ID" value="ODM96596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUB0"/>
    <dbReference type="OrthoDB" id="8267216at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694:SF11">
        <property type="entry name" value="LP21121P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36694">
        <property type="entry name" value="PASIFLORA 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30983" checksum="4DD2CB45079F9FBB" modified="2016-11-30" version="1">MGKRTVNPTCGLMSLKRASQIMAIIDMVFGLVGIGWFIYMFKKHGIISLEAFEPTLGIDASSVTDTNGTSSKLFHDLASGNVNSTNPTVNVYGTQKELLSLTLSGYFIGYFYTGVNLTIFVFLLLGVYRRSPALCMFWFNVRCAIVVYKVAILLMYIIAGLNFQMFQIPWILTMVIHVYGLWLVNCYVNELRVEQFCRTCCKNQADAKVGKGNPPSIITQDSTMVEESESRKNNSISSFDNPDELWNGIEIIQRRRLSSPTPGIENPLHDSDGHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUW4</accession>
    <name>A0A1D2MUW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000521">
        <property type="protein sequence ID" value="ODM96604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUW4"/>
    <dbReference type="OMA" id="AMERNHY"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="167" mass="18318" checksum="119A2968A4DC78BC" modified="2016-11-30" version="1">MHPCCGKDLRSATKLAAVIDIVWTSIFVALGIVIIITSATSLRVEKNEQSESPEDTTFAMGGLIVGTILLVVKILQLILAIFLLQGAMERNHYKCKIWIYITCVFVTITVMNFLFDVISVEGSKTGSVGSVIGIILHIYFLWIVWAYKKELEQGLAQPEADAGGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVM1</accession>
    <name>A0A1D2MVM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ subfamily C member 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09959</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000509">
        <property type="protein sequence ID" value="ODM96725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVM1"/>
    <dbReference type="STRING" id="48709.A0A1D2MVM1"/>
    <dbReference type="OMA" id="HWAVRDK"/>
    <dbReference type="OrthoDB" id="436519at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029827">
        <property type="entry name" value="JDP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44500">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44500:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="21931" checksum="488C4CBA23DD92D6" modified="2016-11-30" version="1">MARGGGGDFGVGAILQGRKGDEDDYFKILGCSDTSTDEQITTEYKIRALKFHPDKHPGDEKALEQFQKLQEARDVLLDPEKRQKYEKWRQAEMCIPYKQWLSMSSRCATTMHWAKPKEQTMIESGAQQKQAEMERDVEAAGAAASSSSSSEAEIKWMSSSLPSTTGSKTDHQQYVWRPEKTTSVYSKFRNYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVT2</accession>
    <name>A0A1D2MVT2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clustered mitochondria protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000465">
        <property type="protein sequence ID" value="ODM97179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MVT2"/>
    <dbReference type="OMA" id="HPVWDKD"/>
    <dbReference type="OrthoDB" id="1414216at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd15466">
        <property type="entry name" value="CLU-central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000099">
        <property type="entry name" value="Clustered mitochondria protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2280.10:FF:000002">
        <property type="entry name" value="Clustered mitochondria protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2280.10">
        <property type="entry name" value="Hypothetical protein (hspc210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03013">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033646">
        <property type="entry name" value="CLU-central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025697">
        <property type="entry name" value="CLU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028275">
        <property type="entry name" value="CLU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027523">
        <property type="entry name" value="CLU_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023231">
        <property type="entry name" value="GSKIP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601:SF6">
        <property type="entry name" value="CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13236">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15044">
        <property type="entry name" value="CLU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12807">
        <property type="entry name" value="eIF3_p135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103107">
        <property type="entry name" value="Hypothetical protein c14orf129, hspc210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51823">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Clu" evidence="5">
        <location>
            <begin position="513"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1430"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="824"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="925"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1068"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1168"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1582"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="27"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="830"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="857"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="932"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1082"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1092"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1181"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1608"/>
            <end position="1617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1617" mass="178433" checksum="030291B9E8D27EC0" modified="2016-11-30" version="1">MKVTDGGDVSTTTIPTEKKENGPTSPINNHISDKSSSSINNNNSSRNSSSSNNNGTRSCSDVSTSSSCSSAGEEQETDLGGEHSSDTLKNGSVLVLNGKSECATNLSSEHGGGSVENGTSDNRSSKAPRNKSSSKKGKSKSATAERNTTSNNNGMSSPSSSASPSEDKSQEKQGESSSNLNTATTSANKSAEQDQDPQRQDSMEKEEGSGGEGSKGEDASTEDVYYVHDSGLTIKIVAPGAEPFEIQVSSTEIVQELHQLLMEREDTCHRTCFSLQLDGNTLDNFAELKSVPGLKDGSVIKVVEEPYTCREGRIHVKHVRDLLKPSDWADAYAGTDCASLSFLNAVSGGELSGKKRVVDCTPPDYIMPGTANSLMLSPLHPLIKDQKPISCLKVLAASGWNPPPGYRKLHGDLMYLLVVTLEDKTCHITASPRGFFLNRSSVDSFDPLPATPNNFLSHSLIELLNQISPAFRKNFTQLQRRRMSRHPFERVATPYQVYSWVSPTMQHNLDAIRAEEAFSSKLGYEEHIPGQTRDWNEELQSTRELPRSTLPERLLRERAIFKVHSDFVSAAARGAVAVIDGNIMAINPGESHKMQMFIWSNIFFSLGFDVRDHYKELGGDAAAHVAPRNDLQGVAAYNAIDLEGLYTLGTVVIDYRGYRVTAQSIIPGILEREQDQSVVYGSIDFGKTVVTNDKYLELLKKAAPRLKVLPHYVFNEKDEMVELCSSVECKGIIGNDGRHYILDLLRTFPPDINYLPGENVELCTDVRDMGFPMEHPHKLCCLRQELVDAFVESRYMSFIKLAAYHLQTMGLKKSLKEATINKAANNEEGTTFPSASTTTTSSAKTSEADNETDDNQPEVKAKTEEISEDKESSDQKMVESITNSADKSEESTTMKAIRQAAVSVCSLSEKEFDIRFNPDIFSPNVRHVNESPIPQDNAPENATSQKDSEPKPESSSDDPTEVSSAKKDATPLKKNPSLELQIRLNKEACEFLALFQIPQFVRDITSNSACALDSGTTFFGPNALIMDGITLSAAMHSRGINIRYLGRVVYLLLDREEQMKESVSKINIVQTNTNNHKDKDTPSNGNGATTNGQSGSQQGSLQSLPHFMTTIAVMELISRSAKHVFNPYIQSVDVMNQCVAISHFLNCFLMSGQNAVSPPVVIDELMPSKQSRGTHGRSKGNKQQSQRAGKTNSNNNGSIGIEWTALTQQSLWEQIRQDIRSYYGFVFPEPVQDSLEEVLSLYGVQKLSLLRSFCLKTGVQIHLREYHFHKNGGAGKTAGNSFSQEDILNVFPVVKHIDPKASDAYTYLGTAQSKMSAGFFREGYELLSESLNLLNNVYGAMHPDIALCLRSLARLNYVMSEHADAMAYQQKALFMAERILGVDHPTTILEYTHLALYCFANNQVTTALKLLYRARYLSLLICGENHPHVALLDSNIGLILHAVGEYELSLKFLEKALELSKKYFGARSLKTAVGHHLVARTQSCIGDFRSALMNERETYSIYKEQLGEKHEKTKEASDCLQHLTQQAVVLQRKINDLAHGKGLPPIQIQPPSMGSVLDMLNLINGILFMQISQQDIENFKAELEHRAREMSPPQKDPKSQPLAIESSPTKDEIPEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVX0</accession>
    <name>A0A1D2MVX0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000473">
        <property type="protein sequence ID" value="ODM97102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVX0"/>
    <dbReference type="STRING" id="48709.A0A1D2MVX0"/>
    <dbReference type="OMA" id="TRCRPYQ"/>
    <dbReference type="OrthoDB" id="10254665at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="498" mass="55357" checksum="FA19DC9F057458BF" modified="2016-11-30" version="1">MASETNSNEDLVTSSSATAAVGGLGADEDGICDGKYVVVERGDQQRIILFKSNQTITFGKGATQQDILLKGASGTGFLNAFKASPAPPEVIASHKPSSNNSKPWKKSKVRPQNLFVLERSTDPIVKSINEFYQLPDTISSGVDNRNIHDDNTSQAMKKHDIESLRGQGVSSKEILETIITSSKSFNQKTEFAQEKYLKKKEKIYGDVLVFRKPSISILSDYYFKRDPVKVLGLRPDTLSQLLSYANIHAHGKYLIFENCCGLIVAAVLNRLGGHGAALHCHIGSNPQRQALVCMNFTDEDLKPMMNLDMLYLLRGNVEKMEVGPDDIAAVAVVEAESSEEPKTKKQKLECDAGSDSDDEKNGKDSYNEQSEVEEETTFVTSRRLMASNNKEDNETSVAYFNETEFDGLIICGKEHPLTLLQRLLPRLALSTPFVIYCQYPEPLMDCYVWVKEKGIGINVHLVDNWFRNIQVETERTHPEINMSPSGGYLLYGTYIVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXW4</accession>
    <name>A0A1D2MXW4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IST1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Charged multivesicular body protein 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08819</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation. Is required for efficient abscission during cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing. Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2. Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with CHMP1A, CHMP1B, VPS4A and VTA1. Interacts with SPAST, STAMBP, and USP8. May interact with VPS37B. May associate with the ESCRT-I complex. Interacts with MITD1, in competition with VSP4. Interacts with SPART (via MIT domain); leading to the recruitment of SPART to midbodies. Interacts with SPAST.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000400">
        <property type="protein sequence ID" value="ODM97867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXW4"/>
    <dbReference type="STRING" id="48709.A0A1D2MXW4"/>
    <dbReference type="OMA" id="FSEIWPY"/>
    <dbReference type="OrthoDB" id="29853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.60">
        <property type="entry name" value="Vacuolar protein sorting-associated protein Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005061">
        <property type="entry name" value="Ist1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042277">
        <property type="entry name" value="IST1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161">
        <property type="entry name" value="IST1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161:SF5">
        <property type="entry name" value="IST1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03398">
        <property type="entry name" value="Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="86" mass="10278" checksum="CD32D73DEA7FFBD2" modified="2016-11-30" version="1">MFSSGPNYQKLKTNLRLSLNRLKLLEKKKTELALKARKEIADYIQDGKVERAKIRVEHIIREDYIVEAMEIVEMYCDLLFSEIWPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ36</accession>
    <name>A0A1D2MZ36_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="9">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08387</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine</text>
            <dbReference type="Rhea" id="RHEA:20517"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:67138"/>
            <dbReference type="EC" id="5.1.3.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 9">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 9">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000366">
        <property type="protein sequence ID" value="ODM98299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ36"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ36"/>
    <dbReference type="OMA" id="GEHLICN"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003974">
        <property type="term" value="F:UDP-N-acetylglucosamine 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007956">
        <property type="entry name" value="PRK10675.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01713">
        <property type="entry name" value="NUCEPIMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="10">
        <location>
            <begin position="5"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="352" mass="38120" checksum="CA94CBA8C68CED01" modified="2016-11-30" version="1">MPKVFITGGAGYVGSHCIVEFLNSGYDVVVVDNMVNAIMGDKGKPTSLVRVEKLTGKTIAFHEVDLLNEAKLKEVFAANGPFDCVVHFAALKSVGESCKIPLRYYSNNISGSINLLNVMAECGCKSIVFSSSATVYGDPQKLPVTEEHPTGSCTNTYGKTKFMMEEMMRDVCVADPEWKAIMLRYFNPVGAHPSGEIGEDPRGIPNNLMPYVSQVAVGARPKLSVFGNDYNTPDGTGVRDYIHVMDLATGHVAAVKKIVDPALKGWKPYNLGTGNGNSVLEVVQAFEAASGKKVPYEIAPRRAGDIAVTYADCSLATKELGWKAEKSLADMCADCWRWQSKNPQGFQVSSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ42</accession>
    <name>A0A1D2MZ42_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_08366</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000365">
        <property type="protein sequence ID" value="ODM98313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ42"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ42"/>
    <dbReference type="OMA" id="FTHAQFL"/>
    <dbReference type="OrthoDB" id="10011262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008365">
        <property type="entry name" value="Prostanoid_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF2">
        <property type="entry name" value="FMRFAMIDE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01788">
        <property type="entry name" value="PROSTANOIDR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="78"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM98313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="437" mass="48880" checksum="5B083846AF2BC514" modified="2016-11-30" version="1">MWNETDDSIVEGSNIATVDPFAGELDESSKYNIFFTTYNPHSPAYSNNITDLGISINLLKFCLEGVGITTVSVLGVIGNILSIIVLSSSRMRSSSSVFLLCLSFCDITVLVGATLLIGIPSLLAYNPEDGRALVFNIMRILQFGYCIPGFYAFTVTAITGSILFTLALTLDRYLAVCKPFFARNLCTWSRAVVVSSVIMVVNILYNLPKWWEYTYVVEETNNFTIYRPVPAAIRTNVIYDTYYTHFSYLVLMFVTPICSLIVLNVLIYLKIREANKLRKNLSPTQKNENSLTKMLFGVVAVFLMCQLFPAILNMTRYLSGDREMTPEVEFVVVFLFVVNSSVNFLIYCAIGGKFREIFCDMFCCWNSNSRIRRLAASTKTTLRSLSLSSSTTTGRSRAFSIQSQGAIQHANAMLAISPPANQQHPQISMISHHILQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZP9</accession>
    <name>A0A1D2MZP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Facilitated trehalose transporter Tret1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08382</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000366">
        <property type="protein sequence ID" value="ODM98294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZP9"/>
    <dbReference type="STRING" id="48709.A0A1D2MZP9"/>
    <dbReference type="OMA" id="CWIRQLE"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17358">
        <property type="entry name" value="MFS_GLUT6_8_Class3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000055">
        <property type="entry name" value="Facilitated trehalose transporter Tret1-2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044775">
        <property type="entry name" value="MFS_ERD6/Tret1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="1"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="445" mass="48981" checksum="EE3FA361616D8EC6" modified="2016-11-30" version="1">MITPAMPDMKKQINASDVDFDLFSDETESWIGSIINLGALASAIVVGILVDIIGRKMTMLLLSAPFVLGWLLLAFAKNSAMIIIGRAITGFCGGGFSLAAPLFVAEMAEDNIRGALGSGFQVMVTFGILFVYVFGSFLTFQWLAIICGFVPLVFLVAMIFIPESPRYLVAKGKPTDASKSLCWFRKKTSSQDVEDEMRIIEMSVNEMKAQASSFSELFESHHLRPSLLMIALMCFQQLSGINAVIFYTSDIFTSAGSTMDENLSTIIVGIVQFVATVSSIFFVDRAGRKILLLISSAVMCGSLVVLGIFFQLKDNGKDEGLGWLPLICLMLFITAFSIGYGPIPWLMLGELIPQKVKARVASLSTVINWGLSFIVTKFFKSIQEALTIQWCYWIFAIICAIGFVFVFLLLPETKGKSIEEIQQYFGGPTSSAQPQEQKKTKEQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0A0</accession>
    <name>A0A1D2N0A0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase inhibitor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein phosphatase inhibitor 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000334">
        <property type="protein sequence ID" value="ODM98702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0A0"/>
    <dbReference type="OMA" id="HAHFDEM"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15606" checksum="7DD883D4227DA1B4" modified="2016-11-30" version="1">MSKNSNTVPAKGILRGKSSSAKKENIKDKCALPSSGTPDKQHAHFDEMNILETYHPEEPVQEEPEQPGARIRRSSVDYNKGSVVDPRTLSTQLVGKKLTPLKSSVPVADTSDDDETAKKKAFKAQRAAHYGKEFVKDTQPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0C2</accession>
    <name>A0A1D2N0C2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">2-oxoisovalerate dehydrogenase subunit beta, mitochondrial</fullName>
            <ecNumber evidence="3">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Branched-chain alpha-keto acid dehydrogenase E1 component beta chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_07955</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Together with BCKDHA forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:13458"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterotetramer of 2 alpha/BCKDHA and 2 beta chains/BCKDHB that forms the branched-chain alpha-keto acid decarboxylase (E1) component of the BCKD complex. The branched-chain alpha-ketoacid dehydrogenase is a large complex composed of three major building blocks E1, E2 and E3. It is organized around E2, a 24-meric cubic core composed of DBT, to which are associated 6 to 12 copies of E1, and approximately 6 copies of the dehydrogenase E3, a DLD dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000330">
        <property type="protein sequence ID" value="ODM98722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0C2"/>
    <dbReference type="STRING" id="48709.A0A1D2N0C2"/>
    <dbReference type="OMA" id="SEAYYMA"/>
    <dbReference type="OrthoDB" id="878at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007584">
        <property type="term" value="P:response to nutrient"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000004">
        <property type="entry name" value="2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="12">
        <location>
            <begin position="84"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00057409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00071568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM98722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="405" mass="44704" checksum="21F5DF645D83FF44" modified="2016-11-30" version="1">MWSNVTPRCVQCIKNKSVVRQLHKTSLKGLCFNPLPVSNRTPTAVGSLQKRISSVLQQWTRSYSAHFTYVPDTVPSSEGETVRMNLFQAVNNAMDIALASDPTAIIFGEDVAFGGVFRCTLNLQDKHGKDRVFNTPLCEQGIAGFGIGAAVAGATVIAEMQFADYIFPAFDQIVNEAAKFRYRCGNQFDCGKLTFRAPCGAVGHGALYHSQSPEAYFAHTPGLKIVMPRGAVKAKGLLLSCIRSNDPCIFFEPKILYRSAVEQVPTRDYELPIGKADILLEGENVTLLGWGTQVHVLREVAQLAQDRLNVTCEVIDLVTIQPWDRETIFNSVTKTGRLVIAHEAPLNCGLGAEIAASVQKECFLNLEAPIQRVTGHDTPFPHVFEPFYIPDKWRCLEAVRVAVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N127</accession>
    <name>A0A1D2N127_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000311">
        <property type="protein sequence ID" value="ODM98930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N127"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="275" mass="30160" checksum="EBE9A4F85F27BEDB" modified="2016-11-30" version="1">MEVESLASFDSDIEVIEDGSLLVLSTISGPEPENKDSDADSIDGLFSMLKETSTDSDDEEANSRSIMELDELISMERENLELIKKANESIRDCVTASVAVVGKTLTSIPVTSETDISNETSSSVPISNGDSPTENETPSSTGEPTEIDNPTNNGSDIKEKDKTEIDTATIITPQKATQKPVSRSAHCSSSQTRSEDRHGCERVYKRLLPISGFREPVHHHRLHPQFHHGAFTLLYFTATKRISRTGAVSTEEKQTQGQLERYELTKTQSTTSGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N134</accession>
    <name>A0A1D2N134_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="9">3.5.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07729</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>AMP + H2O + H(+) = IMP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.5.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000308">
        <property type="protein sequence ID" value="ODM98948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N134"/>
    <dbReference type="STRING" id="48709.A0A1D2N134"/>
    <dbReference type="OMA" id="YYMFANL"/>
    <dbReference type="OrthoDB" id="1723809at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000035">
        <property type="entry name" value="Probable amp deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001251">
        <property type="entry name" value="AMP_deaminase_met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="378"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="977" mass="111766" checksum="3D7E4A598D2049C0" modified="2016-11-30" version="1">MALLNQPTMEAPNEAEAEKGSVAPLNGSVAASSNLNGVNGQGAVNKFNISIALGNENGEKKKKKKKVDENGQEVEGEENDEGSESPSYGSPTSFQIPRIRHSQLDDTYEEMAGTILMQETVQQQIANEISAPYEVPQFPIEQIETKLALQRQLSIRQRDNEARSQTYEPSLGPQIDEVEGASGSKMDPFDLVPPFQRVSVSGEDTSGVPYEDLVHASKYLVNALRLRESYMAKSRQSFPNITSRFLSAVDGDGGTPPKEVHHDDRRTIEVLEVNVTEDELILLNPDPVKMLQESMSDMFDDEPESFTIRPTDAVSEFSFKMSKRLEALSEDELEAFNRSSYIGSMAEELKVTQAKSLDLDDDSLEKVDSDVEFKSKVSLNDVSQPGHSKKENPRRSARLSAKDHPIHPPPSAVNPWEIEFQPSLNYKFKFKEGIAHVYESDKHLKDDKPIEYPVPTMLEYVRDMKIMCVMIADGPLKSFCYKRLSYLFSKYQLHVLLNEVQELTAQKTVPHRDFYNIRKVDTHIHAASCMNQKHLLRFIKKTLKNHSEEYVCNDESGKPMTLNQVFESLNLTAYDLSVDMLDVHADRNTFHRFDKFNAKYNPIGESRLREVFLKTDNFNGGKYFASIIKEVMFDLKESKYQNAELRLSIYGRSRDEWDKLAQWAITNNVYCDNVRWLIQVPRLYDIYKAKNLISNFQEILENIYMPLLEVTNDPKSHPELHQFLQYVIGFDSVDDESKPEHPLFDKNVLTPDLWKIKENPPYSYYLFFMFANLSVINHFRRERGLNTFVLRPHCGEAGPVQHLVAAYLLSENISHGLLLRKVPVLQYLYYLAQIGIAMSPLSNNSLFLNYNRHPLPEYLARGLVISLSTDDPLQFHFTKEPLMEEYSIATQFWKLSACDMCELSRNSVLMSGFPHKLKQYWLGPNYTKDGVAGNDISRTNVPDIRVCYRYETLVEELANIFKVVELVSKVKATEAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N176</accession>
    <name>A0A1D2N176_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N176"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904872" evidence="1">
        <location>
            <begin position="23"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="470" mass="53704" checksum="222E26D8A437F43E" modified="2016-11-30" version="1">MRLTITIFIYSTLAFVAKIADSQATCGLINVTSSPENRFRIPAASDHLIDKTLIWEHPLFGEINTTLAESHPHFIYVDATRTVSLYRFYSNEKTRLFTRDMETREVIRNVNIYCSDGTIEKYYFEIPLQDITPPEFREPFYSMNITTNWGSERPISEGQVIIVADNDYELGIEDLDKNLRFESSPGVLNVVPRKLSGENEPNPEMFYYQLDLYFKEGVNLPPGTLQLGLSASDDSNNSHGQTTPSSCGLVGITSSENSRYRIPVISDYLQKDEILWRHRFFGVVNATAGSGHAHFKYIDATRTTSEYRLKANTLTRHFARDFSSRLAIRDFTLTCYNGDLSRNYIEIPMQDMTPPEFSQPNYTMHVPQNWDITKPISEGQFIIISDNAYELGLESPETNLNFTTPSIPEFLEIKPIKMWVQPKPEKFYYRLDVFIKKNVSIPPSGIHHVPLSASDEFNSGTTTLIINITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1E2</accession>
    <name>A0A1D2N1E2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sodium/nucleoside cotransporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07639</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1E2"/>
    <dbReference type="STRING" id="48709.A0A1D2N1E2"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005415">
        <property type="term" value="F:nucleoside:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="618"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="8">
        <location>
            <begin position="229"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="10">
        <location>
            <begin position="332"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="9">
        <location>
            <begin position="432"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM99031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="641" mass="69677" checksum="0039D5747D5F403B" modified="2016-11-30" version="1">MEHSRISGGNGEEFQHRGIELESQDVDLELSPLNNGGGDQVSPPDQLLDEVELNAVEDPRVHKPQFEDLECDENSLNPINRFLTRAHSNIQRLLERLKKKQVVKWAGFLLIFTVHIVYLTFAILHKQDKGLEWKWCDGHGLLIILTVFSYAFPVYITVVKPFLSNWISNAVSRSWPNWSSGTVGSASMMCKRWYVKPIVFLLIISVVITIIVVDALNDNQPLRIVSMGGVLGILLIGLFCSNNPGRVTWGPVIGSLVAQSCLGLVALKWDAGRHFLECFSDKVNTFLRFSFTGANAVFGHLSSGSLTIVNSSYLPLVDQTLVLNPVFVFGPLSVIYFLAFMVGILYHVGAMSSVISKLGSVIQKLIGTSAAESMNAVASIFLGLTEAPLLIKPFLNDLTNSELHSVMAVGYSTVAAGTMALYISLGVNASSVIAASVMAAPGGLAMSKLLYPETQKSKTCSSNIKSYQPETEGTALGAGMRAAGDAVMLIAQIAANLIAVIAFVAFLNSILSWLGDLVGQPDIWSFEYFLSKLLFWIALCIGVEPKDAEDVALLLGLKTVVNELVAYQKLVKMTSLSFRSRTIAEYALCSFANFCSVGIQLGGLHMLVPERRADLSQLVWRALFTGVLSSLLNACVAGVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1N6</accession>
    <name>A0A1D2N1N6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lipase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07556</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000298">
        <property type="protein sequence ID" value="ODM99121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1N6"/>
    <dbReference type="STRING" id="48709.A0A1D2N1N6"/>
    <dbReference type="OMA" id="IQEWING"/>
    <dbReference type="OrthoDB" id="6480624at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000057">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904901" evidence="8">
        <location>
            <begin position="27"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="9">
        <location>
            <begin position="78"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="451" mass="49782" checksum="C1103A734C00F526" modified="2016-11-30" version="1">MANPICFWSICIIILCTLSNKHSPLALTLTPVIRTPNLPVCAPSTVPATALPDDFLTCSQKVAENRNKTHPDIGKRTDEIITYYGYSSEIYNVTTFDGYILTIFRIPGSPKSPPAQGKPAVYLNHGITQNSDNWLLAYRDRNLAFKLADAGYDVWLSNCRGNSYSLGHETLNSETDSEYWDFSWHEMGVGDVPAAVDKIISVSGNEKILYVGYSMGCTQYFVGLSEIPSLNDKLKAAVLLAPPAYMGHATNPIRLVGAATVVGGQNIVGPLIGQRVDEPTKFQEYFNVSLGNFCTPTAARCGVCDNFGYLVFGFDAPQTNYTNVPNILSKIDNASLKTAAHYAQSINNCWFRQYDYGPTKNVARYGTVVPPSYNLTAITVPTHFIHGEADNFVVPNDVQITRDHMRPGVVKEVIKVDWSLFNHVDFVNAKDADTLVYNKVLQILNNNINTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1P0</accession>
    <name>A0A1D2N1P0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">xanthine dehydrogenase</fullName>
            <ecNumber evidence="4">1.17.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_07709</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24670"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>xanthine + NAD(+) + H2O = urate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="19">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="19">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000306">
        <property type="protein sequence ID" value="ODM98964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1P0"/>
    <dbReference type="STRING" id="48709.A0A1D2N1P0"/>
    <dbReference type="OMA" id="PHPTQER"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000015">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000003">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000002">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.50:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014307">
        <property type="entry name" value="Xanthine_DH_ssu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02963">
        <property type="entry name" value="xanthine_xdhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 19" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9 18" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 19" id="KW-0408">Iron</keyword>
    <keyword evidence="12 19" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 19" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="20">
        <location>
            <begin position="8"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="21">
        <location>
            <begin position="226"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="254"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="767"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="798"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="802"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="892"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="924"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="926"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1022"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="1091"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODM98964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1256" mass="138429" checksum="2EE0C5202561E95E" modified="2016-11-30" version="1">MLFPTKSSPLVFYLNGDKIVDEHVNPEWTLLTYLRNKRRLPGTKLGCSEGGCGACTVMVQRFDREKKKIVNFAVNACLTPVCAVHGMSIVTVEGIGSVAKGLHPVQERIAKSHGSQCGFCTPGIVMSMYTLIRNKNVPTMDEVEVAFQGNLCRCTGYRPILEGFKTLTVEGGAGGCCGAGMQSGGCCGGQAMKNGGSGCCMQNASEPIFPPELQLTEKYDTQYLVFNGERLTWYRPTKIEQLLELKATYPYAKLVVGNTEIGVEVKFKNCHYPVIIQPNHVPELVEIRVEDKGIRFGAAVTLSQIDDVLQEQIAKKPAYKTRVFKAIVEMLRWFAGKQIRNAAAVGGNIITGSPISDLNPLFMAAHCELVLRSKNETRVVQMDDSFFTGYRKNILKSEEILTSILIPYTKEDEYFWGFKQAKRRDDDIAIVNAGMYVRFSVGTNVIANINLAFGGMAPTTVMARTTASSLIGHQWNEGVVDVASKTLIEDLPLAPSAPGGMIEFRRSLTLSFFFKFYMIVQDELSTKLPYVKPLPQIYKSATSLYHRDPPQSIQLSQIVPNEQPDYDLVGRPVAHVSASKQATGEAVYIDDMPKFENELYLALVMSSRARAKILSIDPSEALEMEGVVDFVSAKDIPNHRNSVGGVIHDETVFAIDEVTCVGHIIGAVVANDQATAQRAAKTVKIEYEDIQPAIITMQDAIKHNSFYNDWIKILKNGDVEKGFSEADHILEGEMYLGGQEHFYLETNAAIALPKLEDGEMEIFSSTQNPSEIQLLAAEVLGVPENRIVVRTKRMGGGFGGKETRGMLVALPVAVAAQKQESNFLEKLISRLKRPIRCMLDRDEDMACTGTRHPFFCKFKVGFKSNGKLTALKLTMYNNAGNSLDLSASVMERAVFSADNAYNIPNVDFTGILCKTNVPSNTAFRGFGGPQGMMFCENVMDQVADKLGMDSVKLRTLNMYKEGDRTHYNQSLTYCTLSRCWNECLENAGYEQRLAEVQAFNKENRWRKRGIAAIPTKFGIAFTALFLNQAGALVIVYRDGSVLMSHGGTEMGQGLHTKMIQVASRTLKISSDKIHISETSTDKVPNTSPTAASAGSDLNGMAVLNACKTIMERLEPYMKSNPNGKWEDWVNSAYFDRCSLSATGFYKTPDIGFNFATKTGTPFNYFCFGAACAEVEIDCLTGDHEAVGEPPLFLAAAAFYAIKDAVKAARAENGKTGPFRLDSPATAERIRLACEDQFTQKFPPAPPNSYKPWSVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Z3</accession>
    <name>A0A1D2N1Z3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF243 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000287">
        <property type="protein sequence ID" value="ODM99317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Z3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004145">
        <property type="entry name" value="DUF243"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03103">
        <property type="entry name" value="DUF243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF243" evidence="2">
        <location>
            <begin position="70"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="194" mass="21837" checksum="C2B51579B3224D3F" modified="2016-11-30" version="1">MVIFLSYTIRNHEDRAGICRFDRVDVRWSWRGNSRGGTEAESLWKQVLRGSFRGVTTGQYEEIAPAPNRSDPTAQAPQQVVFVRPPTYTYKHDVVVTGGGASGQKTVIYVLPSKNKNQVNLVDNTSNTVVTQKPTVYFLKKDHDHSKSQEEVGSQPASPHPGVTCRHQRTRQRYNYQPLGVGTTNANFVKAFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2B3</accession>
    <name>A0A1D2N2B3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2B3"/>
    <dbReference type="OMA" id="NGIRSCK"/>
    <dbReference type="OrthoDB" id="3233795at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904919" description="EB domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="14756" checksum="5C3D8DBFD8DAE709" modified="2016-11-30" version="1">MTSTFSIIVVISLIALVNADTIKKRIVNVDIGGHCSLGAAPVGPGGSWQVVEKDVEKVCAKGTSCRKGACNCDDLPDGTVTGLSSDAQGNRVCRNVAGQKCSSNNDCFEDVQCLQGVCTCDKTKKDFYCVDAKNDVYILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2J4</accession>
    <name>A0A1D2N2J4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein krueppel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000275">
        <property type="protein sequence ID" value="ODM99503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2J4"/>
    <dbReference type="STRING" id="48709.A0A1D2N2J4"/>
    <dbReference type="OMA" id="GARAHIF"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048598">
        <property type="term" value="P:embryonic morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045596">
        <property type="term" value="P:negative regulation of cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001498">
        <property type="entry name" value="Zinc finger protein 404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000912">
        <property type="entry name" value="Zinc finger protein 660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF66">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="414"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="442"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="178"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="322"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="494"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="575"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="185"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="584"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="660" mass="72058" checksum="84DEFA1896A7BCA1" modified="2016-11-30" version="1">MGYRHVALLDKLVKKKITRLRISIGARAHIFKIHGLIPVNPSTSQELGAKQIDSYFGEENGGVMKEHGDKCSTTTRGLPPSAHIASDKLMRDQELRHLVTSSIPSPPYAGLSLINASAALTVFGDPIYSSHLFASLAANNANVRFQLPIAGFAGIPGATVPSQAQLDILSSWVNEQARKDDQKITSTTPTTNGSVTNNNKISSSNKSKRNNNVDSKNNKNVSKTALTKQKRSANGNGNLAVTKANRKNKTGRNNGAIISSENELLARKEKFEKEAPEPMNIHESIIQPFILPLDKSPVASIQMDVSQSPPIKSEKLISALNGRADSPPAMNNNNLNGVSKNGSQQTSPGSNGPRDKVFTCPTCNRCFGYKHVLQNHERTHTGEKPFECTICMKKFTRDHHLKTHMRLHTGEKPYQCTHCDRQFVQVANLRRHLRVHTGERPYACELCSSRFSDSNQLKAHMLIHKGEKPYSCTECGGKFRRRHHLAHHKCVEDGNNKRLGFHPPSSSSPDTSPPQLTPGNGADSLSNGNGSVGKRGRKCRETRRIIRLETLPASTVTTINPLTYLADSVVPEQTVPEDLSMGGSTIRSRNYSGSSSSVTASSPSPRSGVSHGSFISRPYCYSNTSSETPDLYSDEDRAADSSTNGKNESSSDDILSPSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2J7</accession>
    <name>A0A1D2N2J7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000277">
        <property type="protein sequence ID" value="ODM99492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2J7"/>
    <dbReference type="STRING" id="48709.A0A1D2N2J7"/>
    <dbReference type="OMA" id="THCLAPH"/>
    <dbReference type="OrthoDB" id="8123669at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="47"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="278" mass="31442" checksum="2C59A62FDDC502A8" modified="2016-11-30" version="1">MSHLYWEGATIAARYAKYRPIPPTGLLNRIVDFLKEKYEGPLNVAYDVGCGSGQSTQFLAPHFSRVVGTDLSPSQVEKATEKNKYPNISYKVSPAEVIPEKDKSVQLISASQAAHWFDLPKFYAEGRRALCDGGVLCMYGYELPKFVWPKDPSKEALLNAALMDFYNGDLAQYVLTPSKELYLGRYTLEKFNISFAPETVRDESFCHDVESSVEDMVGYTATWSGFNNFCQQQGDEAGVKLLEKYQSKLMEILNVPTSPEETYFTKRTSYFILMGRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4M6</accession>
    <name>A0A1D2N4M6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="6">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_06467</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000223">
        <property type="protein sequence ID" value="ODN00213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4M6"/>
    <dbReference type="STRING" id="48709.A0A1D2N4M6"/>
    <dbReference type="OMA" id="WEVRHTG"/>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030514">
        <property type="term" value="P:negative regulation of BMP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045879">
        <property type="term" value="P:negative regulation of smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048260">
        <property type="term" value="P:positive regulation of receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd08382">
        <property type="entry name" value="C2_Smurf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000017">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000024">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000079">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024928">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF395">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SMURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001569">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="C2" evidence="10">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="11">
        <location>
            <begin position="269"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="11">
        <location>
            <begin position="313"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="12">
        <location>
            <begin position="560"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="180"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="358"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="358"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="446"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7 8">
        <location>
            <position position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001569-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN00213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="897" mass="99336" checksum="6E6C6E3DAD765674" modified="2016-11-30" version="1">MKLHSSTNRKPIKPKYFCIRVSVFGAKSLVKKDFFRLPDPYAKISVDGTNQTFSTEPCKATLHPTWNQYFDLYLTRTDSITISIWNHKKLHKEQHSGFLGCVHIVGKAVQRLRDAGPQLISLCKASPNDQDVVRGQIAVSLMSRDAHAAGGSDRLPPTAVVDRMGNVSCFGAIEPSPLPSTSLLPIQSATSHSQQPSPRESHSQGQQPPPPIDTVSPLPQTQQQRSSSGTPQQSNSVSSGQPPSSGNSSNNGRRKVKKNTQQTLVNACVGLPEGYETRITEQGQVYFYHVSSGTSSWYHPGVPKELSPGHNFGPLPPGWEQRSTPSGKPYFVDHNSRTTHFTDPRLIRGLSVHSGVLSTIPRGGIGSPPISSSSSSSSSTPQTPSGQTSRHSHNNNSSSSNSNNNHSNSNGHHQSSSSSSASPTGPAPVSGSRSSRSNRRDSQPLSSRDPNTASSSSSSSHQSNNSGGVVVVSSPNSEACPPPPVPRNRERERVPVPVAVNSGNNDGVEMLPKYKRDLNAKIKALRMELQLLQPRNGHCRIEVTRKEIFEQSYRQVLKLRVKDLRKRLMVKFKGEEGLDYGGIAREWLHLLSHEMLNPSYGLFQYSHENQCCVQINPDSGVNPDHLTYFQFVGRVLGLAVFHGHHIDGSFTLPFYKMLLNKSITLSDIQAVDPELHQSLTWMLHNDITGVIESNFCVERDSYGVIQSKELKPGGRDIAVTEKNKEEYVRLFVNYRFMRGIEQQFLALQKGFYEVVPANLLKMFDEKELELIIGGIGKIDIEDWKANTKLKACGPMDRIPIWFWEIVESYDEEMRARLLQFVTGSSRVPIQGFKNLQGSTGAGTPRLFTIHLVEAPTTNLPKSHTCFNRIDIPNYESKEKFYEKLTKAVEETCGFSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4N3</accession>
    <name>A0A1D2N4N3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytokine-like nuclear factor N-PAC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glyoxylate reductase 1 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nuclear protein NP60 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Putative oxidoreductase GLYR1 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_06451</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000222">
        <property type="protein sequence ID" value="ODN00228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4N3"/>
    <dbReference type="STRING" id="48709.A0A1D2N4N3"/>
    <dbReference type="OMA" id="QMISGIT"/>
    <dbReference type="OrthoDB" id="21615at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05836">
        <property type="entry name" value="PWWP_GLYR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000058">
        <property type="entry name" value="Putative oxidoreductase GLYR1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035501">
        <property type="entry name" value="GLYR1_PWWP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF2">
        <property type="entry name" value="CYTOKINE-LIKE NUCLEAR FACTOR N-PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="9">
        <location>
            <begin position="87"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="214"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00078412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00082969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN00228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="629" mass="69559" checksum="407849952A0AC62F" modified="2016-11-30" version="1">MDIALLRLFQRLPKTLLQIVTNFPAFGKASDKRYFLCAESSARTREDGSEKCERAPKLKPRSECAASRIVEEEETSYGAREFCLVYLLHNIAAKMKGWSPWPGKVCSPTPELMKSKSKTTNKNQYCIWFFGTNNYAWIEEHSIKDYEQYKDRLSKTCKNAAFKEACTAIEDYIARKAAGIDVDAELFPEPTPGSEMQEPITQDSSAELDDTFDETKEDNDLDESTVNEEETSTASTPQSKKRKSADDPISESPEKLSAPSQKKKKTSVRNGESFTKKRKAVSTTPVDGTTSFVKYPNHAPRRSAADMFLDRPSSFKPAREEGPLNVSAVSQYLKDKKVIPSKLKFGFLGLGIMGRGIVKNLLNSGHKVVVWNRSPDKCKDFIEAGAEQGMTPSDVVSSADITFSCVADPQASKDMVFGNCGVLQEIDTRKSYVEMTGIDAETSKDIEEAIAIKGGRYLEAQLQGSKQESEDGQLVILCSGDRSLYDDCLTAFSAMGKTSFFLNSNAGSSTKMNLVLQLIAGVMVSGLAEGMALADRVGLEMKDVMDVLALTSMSCPFINEKGSFMVDSQFPTRMPLQHMQKDLNLALGMGNSFEQPLPMAATANEVFKHARRLGYSEHDCAALYIRARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5G3</accession>
    <name>A0A1D2N5G3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Histone-lysine N-methyltransferase trr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_06169</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000202">
        <property type="protein sequence ID" value="ODN00513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5G3"/>
    <dbReference type="STRING" id="48709.A0A1D2N5G3"/>
    <dbReference type="OMA" id="SCKNHAP"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098687">
        <property type="term" value="C:chromosomal region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044666">
        <property type="term" value="C:MLL3/4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005700">
        <property type="term" value="C:polytene chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042800">
        <property type="term" value="F:histone H3K4 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15666">
        <property type="entry name" value="ePHD2_KMT2C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19171">
        <property type="entry name" value="SET_KMT2C_2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000003">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.360:FF:000001">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000002">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45888">
        <property type="entry name" value="HL01030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45888:SF6">
        <property type="entry name" value="HL01030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05964">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00542">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00541">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 19" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="18">
        <location>
            <begin position="508"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="16">
        <location>
            <begin position="886"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="17">
        <location>
            <begin position="1010"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODN00513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1026" mass="116489" checksum="7759CE184F285ACE" modified="2016-11-30" version="1">MDGKKNDDDAKKLKRRQYQAKRKQSMPKDSPVSKKRPRKVGRPEDDYDGFLDSFMTQLRQLSPIGIVEPELGHSHTVCPVYGTGDFSKLNNKTYNTFHGDLSGAFGRGNLPSKLDFYNSRPYTNEPSKPAPKPQPTHRGFYCQEFATPKLGTFVEKVRSDNRTPTPVRETDTPDTIVSASSPECGTWDNITMYPGLKYIDDDFDRDLERCISPEVPLLVPIPIRPVPLDRSKDLTKEIKDMDKENKNGIKDGVNGTKLRSFTPLKEAGNITVTLTLSSAAAEDIRGLLRNLANVLSIAAPTYQVIDKAGASIPEQKSHLYTIKGKDGKEKIDIQSILNGAAKFCRHCDVVVLSNVIKRKVLDFPGVQPTPLNGGDPSEDFYFCSTTCLMQFSITHGVTITEEKAATVVNHPGDTKNIKSEQRLKESKKNKLLDQKALDELKLKNKMKEDVDDKNVPKTDKRWKGSRYRNWGSTFIPQTKYRKPTDKEVTEMLFRLGITAMPSKVPLDTRECIFCHQPGDGVSNGPGRLLNFDVDKWVHLNCALWSDEVYETENGALVNVEVALKQSLTLACVVCKLKGATVKCFKTRCSQVYHLGCATKEGCIFYKNKVTIHHSYIQTIYCPAHIPKGEKENELTTLSVYRRVYIQRDENKQVAAVMHHADQHHLLRVGSLIFLNVGQLLPHQLAAFHTPNFIYPIGYKIARFYWSMRKVNKRCQYICSIHDVDAKPEFRITAQEEGFKEHVVKGNTAQAAWLQILETISKLRNSAEIIKVFPKYITGEDLFGLTEPSIVKVLESLPGIETLTDYHFKYGRNPLLELPLAINPTGCARSEPKLRTHFKRPHTQRTGPSRSTMNMQPISSEAACPYSKQFVHSKSSQYKKMKQEWRNNVYLARSKIQGLGLYAARDIEKHTMVIEYIGEIIRPELAELREKKYEASNRGIYMFRVDENRVIDATLCGGLARYINHSCNPNCVAETVEVDRDLRIIIFANRRISRGEELAYDYKFEFEDDQHKIPCLCGAPNCQQWMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5Y6</accession>
    <name>A0A1D2N5Y6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Macrophage mannose receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_05991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000192">
        <property type="protein sequence ID" value="ODN00689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5Y6"/>
    <dbReference type="STRING" id="48709.A0A1D2N5Y6"/>
    <dbReference type="OMA" id="NWKWINE"/>
    <dbReference type="OrthoDB" id="6703846at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006585">
        <property type="entry name" value="FTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00607">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="C-type lectin" evidence="6">
        <location>
            <begin position="132"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="257"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN00689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="34836" checksum="C6D8C3849F724FD6" modified="2016-11-30" version="1">MLLNVAAGKAPMQSSVAGNGVPQKAVDGSASDFYNPATCTLTQPERLHGGNNRPDLGVNPICNNYTGIIEEGKPLFLPCNPPIKGAFVSVQLQSPPGHALSICEAFVYTDQALPIERCPALRDQPPGSTATYHGKCYTFYSQQALRFEEARQFCAARGGSLVDETNAALHGFLSWEMWLRHRTDPLAQYWLGLVRDLRDPRNTDNWKWINSNNVSLSFWSSPPGRGNCARFDGSKGWLWSDANCNEPLNFICQHRPTGCGRPEQPPNSTLIATSLDVGARIEHKCDEGHLHVGPTTRTCMPDGFYSEFPPVCRSACV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N641</accession>
    <name>A0A1D2N641_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein sidekick-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000191">
        <property type="protein sequence ID" value="ODN00701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N641"/>
    <dbReference type="STRING" id="48709.A0A1D2N641"/>
    <dbReference type="OrthoDB" id="6138780at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="6936" checksum="C744232141678293" modified="2016-11-30" version="1">MVIQKWVDVFQVLGLQPFTVYSFRVAGVNALGRSPPSKESYYFVTLREGKIDFDLSGPSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N643</accession>
    <name>A0A1D2N643_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">26S proteasome non-ATPase regulatory subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05978</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000190">
        <property type="protein sequence ID" value="ODN00724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N643"/>
    <dbReference type="STRING" id="48709.A0A1D2N643"/>
    <dbReference type="OMA" id="RLHCKVD"/>
    <dbReference type="OrthoDB" id="1452at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005838">
        <property type="term" value="C:proteasome regulatory particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000005">
        <property type="entry name" value="26S proteasome regulatory subunit N7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049549">
        <property type="entry name" value="RPN7_PSMD6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21154">
        <property type="entry name" value="RPN7_PSMD6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="206"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="402" mass="47226" checksum="E81996BE265A2367" modified="2016-11-30" version="1">MPLEVQEEGLEKNPDLQLAQWKHLLLQPELSERHDRVKILDQLHTVIKKENMAPFYEELVRDLKKDVNNSVATSLPGLADDVVATMKERNAEKIQEFDAFIEDAEKNLTEMEVRENNLKKAEYLCRIGNRDDTIVAFRKTYEKTVSLGQRLDIVFNQIRIGLFYMDHDVITRNVDKAKILIEEGGDWDRRNRLKVYQGMYAMAIRDFKTAADLFLETISTFTSYELMDYIDFVKYTVIVSMVALPRNELKEKVIEGAEIQEVLHSQPKLKTYMMSLYECKYGDFFKRLADVETELKEDRLLNPHYRYYVREMRIKAYSQLLESYSSLTLDYMANSFGVTKEFIDRELHRFIAAGRLHCKIDKVSGIVETTRPDNKNWQYQSTIKQGDILLNRIQKLSRVINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N668</accession>
    <name>A0A1D2N668_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000187">
        <property type="protein sequence ID" value="ODN00769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N668"/>
    <dbReference type="STRING" id="48709.A0A1D2N668"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="6">
        <location>
            <begin position="201"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="367" mass="41273" checksum="28C88C390597D9A3" modified="2016-11-30" version="1">MATHISQPIGMNGSDSQKKSLPPPPNNVPFMMVVTDVDEEPSVETEKMNSTEALQKTESHHHGLKFRLTKSKPKVNGKREEPETQLSTWDASEDKNDSTPVQVDSTGKPATRWRRICKCLIGMKIKNKNMPMPNEVSPEISPSNYNFDARKASTYSFDFEALSPNPMSTLRLSPDLRQRKSVSPARSEIDFYLYDMGGMSDILNVHEVRQLSKSFPASAVGSPCILIFSTSEDGYSLHNLYRKMSKLNQDTPIIIVIQDSKGRTFGALLSCTLKTSEHFYGSSDSFLFRCGPPMEVFKWRVGENLFFIHSEENFLRIGAGGGKCGLWLDDNLFHGRTEECATFDSPPLVDEKDFEIKSLECWTFGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6C0</accession>
    <name>A0A1D2N6C0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative pyridoxal phosphate-dependent acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000186">
        <property type="protein sequence ID" value="ODN00781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6C0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="9254" checksum="3FC41D9B2D953F2C" modified="2016-11-30" version="1" fragment="single">MQNTDQQHQQDQYNAATGYKKVPIVGGFAAGTKNLIHWKKKVKAKFEYETSVTVHEPSNAKEEGLSFAGFVFDAMSNADGSSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Z1</accession>
    <name>A0A1D2N6Z1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05658</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000175">
        <property type="protein sequence ID" value="ODN01039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Z1"/>
    <dbReference type="OMA" id="IHYCHEH"/>
    <dbReference type="OrthoDB" id="548217at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000049">
        <property type="entry name" value="cyclin-dependent kinase-like 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF400">
        <property type="entry name" value="KINASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="4"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="196" mass="22654" checksum="486D941076ACCC1D" modified="2016-11-30" version="1" fragment="single">MEKYEPLGVVGEGSYGVVLKCKCRDNGKTVAIKKFIDSEDDQNVRKIALREIRVLRKLRHENLVNLIEVFRRRKHIYLVFEFIDHTLLDQLEQKSHGLDEDTCRKYIYQILRGLNFCHENNIIHRDVKPENVLVSKNGIVKLCDFGFARNMCGPGEVFTDYVATRWYRAPELLVGDIAYGKEVDVWALGCLFAGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N741</accession>
    <name>A0A1D2N741_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine protease snake</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N741"/>
    <dbReference type="STRING" id="48709.A0A1D2N741"/>
    <dbReference type="OMA" id="DWIESST"/>
    <dbReference type="OrthoDB" id="6380398at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="17"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="24121" checksum="64F679858502B214" modified="2016-11-30" version="1">MQTFRQIVGKKFGPPTKLLLGDITLSKRTSNTREMSGVARVFVHPNYKPPQTYHDIAIIQMSRKIRLSKSIMPACLPQAEDDLLKKVSSKNFTASGYGITGVGEAQSDTLQVVNLSGYAWDTCNAFYREIPTWNIKFPDGITRTQICAGDAIGRKDTCQGDSGGPLLLPDKTKRCIFNVVGITSFGPNQCGEKAPAIYTNVLSYLDWIESIVWPAKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8F2</accession>
    <name>A0A1D2N8F2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adenylyl cyclase-associated protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000148">
        <property type="protein sequence ID" value="ODN01532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8F2"/>
    <dbReference type="STRING" id="48709.A0A1D2N8F2"/>
    <dbReference type="OMA" id="KSQQTHK"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008179">
        <property type="term" value="F:adenylate cyclase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019933">
        <property type="term" value="P:cAMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.330:FF:000001">
        <property type="entry name" value="Adenylyl cyclase-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.70:FF:000001">
        <property type="entry name" value="Adenylyl cyclase-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.330">
        <property type="entry name" value="Adenylate cyclase-associated CAP, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028417">
        <property type="entry name" value="CAP_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053950">
        <property type="entry name" value="CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036222">
        <property type="entry name" value="CAP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21938">
        <property type="entry name" value="CAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101278">
        <property type="entry name" value="N-terminal domain of adenylylcyclase associated protein, CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01089">
        <property type="entry name" value="CAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="6">
        <location>
            <begin position="329"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN01532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="488" mass="52958" checksum="7B214445CB4E0386" modified="2016-11-30" version="1">MSNESKSTPEYGRLRNFWQSKSESTTDGAPKSAVKPTGNGIESRTNGHSSSSSSSKTDGFNSRKSSMGDDITPAVSEFDQDILTSSLAEFLQAAEKLGGEVAEHGRLVQKAFNAQRNFLLTATKFAKPSDAEFQNLLTATANSITEIQQFRESRRSSPFFNHLSGVSESIPALAWVTVAPTPAPYIKEMNDAGQFYTNRVLKDFKDKPGHAEWAKSWVGTLTALQTHVRKHHTTGLVWGKLPMAGAPAGGPPPPPPPPAFEMPNLEDLQVSDDRAQLFAELRKGEDITKGLKKVTSEMQTHKNPTLRTAGVVPATGKAPVTNGQGPKAPVAKPPKLVLEGKKWVVEYQIGQKDLKIEQVELNQVIYIFGCKDSTLQIKGKLNSIVVDSCVKCAIVFDSLLASVEFVNCRDCQMQVMGTVPTITIDKVDGLQMYLNKDSLNVEIVSAKSSALNVMVPKADGDFAEHPVPEQFKTTIGQKGLITTATESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8J4</accession>
    <name>A0A1D2N8J4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Otopetrin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05067</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the otopetrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8J4"/>
    <dbReference type="STRING" id="48709.A0A1D2N8J4"/>
    <dbReference type="OMA" id="DGFLITC"/>
    <dbReference type="OrthoDB" id="6429739at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015252">
        <property type="term" value="F:proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004878">
        <property type="entry name" value="Otopetrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21522">
        <property type="entry name" value="PROTON CHANNEL OTOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21522:SF61">
        <property type="entry name" value="PROTON CHANNEL OTOPLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03189">
        <property type="entry name" value="Otopetrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="540"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="612"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="641"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="19"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="691" mass="77450" checksum="3DE84BA6A41CB796" modified="2016-11-30" version="1">MGWLFSHVIKKRAKKKITRGVNSIKSRLQSPNKAVTEGGEASSEDELADPAVLYPETDNEAGIGSDLENSKPSKEVTSCSHSEDSDDQLTPLPTDEGGNKTPLMPRQMANNHPTILIQPMNSHLHPHPHNLHVTINSVPGHDGMPTTPPLLHMSNMKKSNIILEALEPPKTKGKLSRTQSVESSKYDSSSGQRSHFGSFYLRMGAVAFGVGSMIYSCLEFGQSLEQGPDTKCHSYMQAITPVVRIVFTFMQMYFIFLNSSMSVSKVSWVKQFGLMHLIGTNLCVWLNVLVQETKHEILHFYDPENGTITVGYGLNYYGKPKKLEEHNKVMAAATSSPPSYPPSALVQDDHDVFLSMVNSTANILSGNGHGVIHRLKRGLKGPHSIYECARENIMGSLVNSASPFLFPCTIEYSLICAAICYVMWKSMAKRRVRQITLKRTMTADSTLNQTEARNVHHYTVDCAGSNKGLFIGIFFLVGTIMSLILNFVLMKHHEHMEFAFWEVNMTEITLYAVSTLAVLIGMCQMRQLRYESGKNLELDNILLIVAQSGSFMFNVFCIVGGQLTPLESNPWILVTPLLCLIQLLLQTLFILDASKRVIANSELARRKPGREIVTFLLVTNLAMWLINALEKSRGDSHPHLLRFFGVWAWTIITDISMPLAIFYRFHSTVCLCEIWKKAYKARKFDSDRLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8Z8</accession>
    <name>A0A1D2N8Z8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">RING finger protein unkempt</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04939</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unkempt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000141">
        <property type="protein sequence ID" value="ODN01729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8Z8"/>
    <dbReference type="STRING" id="48709.A0A1D2N8Z8"/>
    <dbReference type="OMA" id="DKERNMM"/>
    <dbReference type="OrthoDB" id="20534at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040594">
        <property type="entry name" value="UNK_Znf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057295">
        <property type="entry name" value="UNK_Znf_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057296">
        <property type="entry name" value="UNK_Znf_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045234">
        <property type="entry name" value="Unkempt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493:SF50">
        <property type="entry name" value="RING FINGER PROTEIN UNKEMPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493">
        <property type="entry name" value="UNKEMPT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23261">
        <property type="entry name" value="zf-CCCH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25427">
        <property type="entry name" value="zf-CCCH_UNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23035">
        <property type="entry name" value="zf-CCCH_UNK-like_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18384">
        <property type="entry name" value="zf_CCCH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="419"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="885"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="419"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="546"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="684"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="548"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="596"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="695"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="938" mass="102030" checksum="A385137E38FEA8E1" modified="2016-11-30" version="1">MKSQMTDHFKQLTPSSNDNFLGIAFVNKGIEEREATTIVRHVLQKQRYICLAVLNCASFSGEILNSNSVRMPSTSASTAGSSTTSTSTPTPSSSGSLAAGLNNSAGESLSASKLVAMLATQTEKPSHYKLVCDIEKYLKEFRVEQCPLFPQHKCTQHRPFTCFYWHFPNQRRRRPILKKRDGMFNYSPDTYCTKYDETNGTCPDGDDCPFLHRTAGDTERRYHLRYFKTCMCVYETDTRGFCVKNGAHCAFAHGEHDKRPPVFDIKELQQQIQESADDGISGPNQLDKERNMMIDDPKWQDANYVLMNYKTEACKKPPRLCRQGYACPQFHNLRDRRRSPKKFKYRSTPCPNVKHGDEWGEPTQCDDGDECAYCHTRTEQQFHPEIYKSTKVKRPMLDTVIKGMTDGDNNVVVTKLYKMLYSIVCHDVFTNNYCPRGPFCAFAHADHEMSINRILPTDTNLGDILSNVLPTTSSAASVALCGMNSVGPIGSKPGESMNGSSNNGNGNNSSAAVSISAANLISSNNSGLDGMAGFLGGLPDFSDVLRNSCRSPPEQQLHSNYVFGNNGSSSGSNNHAPGAPFGTQSFASAAAGGSSVDNRPSNNNNGSHPVSSIVNHHSGKFFDDRRDGSLVGPGPMANLMNGPVGSSWKAAGNGSALGNQQSLYDNIDNAFSIGFPMEPDRDYSLFPSAGLKQSDQSRDDSPSVVEKELEMDHFTSGGSKPVTIPVSSSVSSNSTNYFSRERFPSGSSSMGNSLNNSFQLGSMFSKPDSVDQADMITNQLGLFDFSSPRTSTLSPRTTTVGSNGLSSSGLSSSIGGVVAPGPVGSTASSTTNSMNGLMGIISRPDLCYQNITTLQHYLKQTKNVMDALSKAISTLSDKDSANYCCLICKQKDKPRTIVLLPCDHQVLCNNCYAVARSCPLCGAAILSRKVASQFPSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9N4</accession>
    <name>A0A1D2N9N4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000132">
        <property type="protein sequence ID" value="ODN01961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9N4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25328" checksum="A0C4A968DA840471" modified="2016-11-30" version="1">MGWAWFTKSVEKTGRWLNFRYIGSPVGMLKIVTLFTLVCSGFALLNGHCNAEYISPAWDDKISPEQRCNAGPKRPIDPVSGKQVWCPQIGLAHASIVFIGVPFVASLILLIVQLFVRFDLSMFTFLHIVGHVIAGLLVMIGAVLCLAFAVEGFNYYQCNDAQCGLPTKNTKLCKGYQEISTCLELRTSYLQPFSFVVAGTFALVGGGAYIVTGVAIKQYGKPKTQQYLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB33</accession>
    <name>A0A1D2NB33_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000111">
        <property type="protein sequence ID" value="ODN02462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB33"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="236" mass="26432" checksum="5694D26EAF8C9B95" modified="2016-11-30" version="1">MLFNLLYRNSSNDILKGIITLKRKVIALPSNITKTEKLKKPKGITGFNLANDAISREAKKNCDAVSCKSKLECIVTSRNRNAFPLLRARHPCGVYGCGRSLSFRARKRVFQFEEKTSKPLVQTVNKGQAGASRDESFNVDNDSDFQVMTTTHIDLINLVSGNPHSQPTPTRKSELFVQQHFRVGLLRLPVGKEAFNRKPKTNSTEPGNSLLSSIFALSTNQPQPHEEQPIQEKQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC22</accession>
    <name>A0A1D2NC22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC22"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="149" mass="16224" checksum="B0BD8D36DB9F1FD5" modified="2016-11-30" version="1">MDNRMSADKSGPTFTVRGGGKINAAGPSAPVPADGKPQETPRNAAAPRQSACVQAQLKVLRQNLERLMGERTMLKDIKISLNKLLSEMEDEILAVKKMRNLSTEATLFMTTKCAEDAVRKRAEDATKAGNSIKTEEPQPHCSKTTFPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDE5</accession>
    <name>A0A1D2NDE5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anosmin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000081">
        <property type="protein sequence ID" value="ODN03251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDE5"/>
    <dbReference type="OMA" id="SCDLRTK"/>
    <dbReference type="OrthoDB" id="10476396at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00217">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="86"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="17117" checksum="80CC67650AEE95DF" modified="2016-11-30" version="1" fragment="single">MNKLRVISNGIVVTILLIVLGEYGVAQMGNRQMRPFQQMGPGNRRPKVAPIMCSHDTLMIYQDCRMCVCPRPNRVAKCFPKSCDLRTKDSGQCPAALLRMDDSKVCALNQFAGCKIDSDCPGPQLCCFDFCGSARCQNPVPLDIISGFPHKGRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDI5</accession>
    <name>A0A1D2NDI5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger homeobox protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03362</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000078">
        <property type="protein sequence ID" value="ODN03313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDI5"/>
    <dbReference type="STRING" id="48709.A0A1D2NDI5"/>
    <dbReference type="OMA" id="RIGTIPM"/>
    <dbReference type="OrthoDB" id="6417226at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051968">
        <property type="entry name" value="ZnFinger_Homeobox_TR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45891">
        <property type="entry name" value="ZINC FINGER HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45891:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN03313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="29970" checksum="7ADAF2CA0D6BE34E" modified="2016-11-30" version="1">MWSGVCEGKIVYNPDGSAYIIEDSELSDDETSLDVPEGCIVDGRGANLQFQSSAIPQIANAIYVSRNPALYTALYGQAYSNLLQDKKMVPDIPIIHSYRVFTIRDSKSDDTSAVEDEDQDGDDEEMETTAKSSSKSNNKSRTKSGSNNNTSGSSVSSKSDKKAPPTPFPECASVPIKPILMCFICKLSFGYTKSFVGHAMGDHKLILNDQENDILNQRNISAIIQCVGKNKDPLISFLEPLGNRIGTIPMSNNAAALSSCSGCSSACRQQQLLFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE60</accession>
    <name>A0A1D2NE60_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_03137</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000070">
        <property type="protein sequence ID" value="ODN03550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NE60"/>
    <dbReference type="OMA" id="CYDRNDS"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 18" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="14">
        <location>
            <begin position="80"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="13">
        <location>
            <begin position="297"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="504"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="672"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="727"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="11">
        <location>
            <begin position="787"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="1172"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN03550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1315" mass="148172" checksum="C2F7107CF4F66D23" modified="2016-11-30" version="1">MRKRKGRAAKGSKTKKLSTPKPKPTPVETNQNVSIPASVPSYANLTGTEDVGGDDDPVPLHELREKVWNVIDSYFAENRGLQSQAIASFNRFVKETLPHIVVKCGRVSVDDRNDAMNKVVHSVEFTCVYLERKVIQHSADGRVFPLYPHEARTRNLTYSSQLSVDIRHTIKKADCAGYETLIKETVHSKVPVADVPIMVKSELCRLHGLTDRELASYLEDPNDPGGYFIINGKEKVIVTQEQPAKNKLFLFKPMCDSKYQYECEVRSTVDSNTDKVSALWIHIPGNPKSYYTFKDSYKLNRFAGGVGGNAKRTNIHSEAVKKSVIKKYFSARPGFVVTIATVRNTVPLLILFKALGFEDDQDVWATFLVDAIDDDFNEALRSTMENPEAKTVKNEEEALYYIGSKSIKEAGSREEVIAHGESVICDEVLPALGSEKMCDRIKGFHLGYMLDRPFLRRLDGGYNYDVEKNIIRQKLVSRGVIYAMTSGNWGDRRRGSPCRVGVSQLLNRLNGTATVSYLRRINSPVNRLVRMTAPRQLHTTAFGYLCPADTPEGETVGLLKALSVMAEVSTDYQKGPIVDCLEAIGYDSIEDFPEKLKTVNIIVVTGYFSLLQYRETKILIDSEIMGTCRLDRVPDVLDGLKRYRREFDVLKEVERRDKRYEDPLYVGTYRGFSHEVSITYDSECKEIRIRTDSGRGFRPLFVVKNNELVLRRKHLRRLLDEGDPYGWKHLIQDGVIELLDAAESEAAMIAMFPENLNGDRKDFLTKTTYRITYSHCEIHPSMILGVCASLIPYPDHNQSPRNTYQSGMAKQAVGVYLTNFQCRCDAESHILHYPQRPLVTTKTAKLINSDDSPNGINTITAICCYTGYNQEDSVILNKSAVERGFFRSSFYRVKTEEEKIYRGRGDMDETFERTRQGQVGVFRHYCYDDVDEDGLPSAGILINDGDPLIGKTQCINLETKNQMLGSGGSRRHIPTKTDVSLLHRSSLASLPSFIDSVILTNNADGYRMVKVKIRCPRIPQIGDKFASRHGQKGVMGMDFSETELPFTKDGIVPDLILNPHAIPSRMTIGHLLETVESKRAALKGIVSDGTCFTPRMSPEEIGGQLEKLGYHKHGIEVLYDGPTGRKMMRQVFIGPVFYQRLKHMTEDKLHIRCRGPITELCKQPCAGLQREGGLRFGEMERDSTISHGASAFLRERLFVVSDYHTIPVCKDCGQFLTRKSTRNQDSVSHLKCRFCNRTSPGAATIEIPYACKLFFQELMSMNIRVMIEPESDIKDFVVLNKEDVENCASLCLYIGDNPVLKIMDKMNGSAAAGYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEA1</accession>
    <name>A0A1D2NEA1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome biogenesis protein BRX1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_03066</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEA1"/>
    <dbReference type="STRING" id="48709.A0A1D2NEA1"/>
    <dbReference type="OMA" id="YRHRHLM"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="8">
        <location>
            <begin position="96"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="22"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="350" mass="40097" checksum="737B01F117F5E9D8" modified="2016-11-30" version="1">MVKVRGKKVALTPSEYVTKDLVGPKGKRGSIAKKKAALKKKQANGTAQNVGKAPKKNKLASEESDIGEVKGNEIILPEIRFSDAPPPKKKMWRNKQRVLVFGSRGISFRGRHTMDNFRRLLPHTKKESKMDKRDSIAAVNEICEMKNCNKCMFFEGRKQGDIYLWLSEIPEGPSMKFLVENLGTMEELKFTGNCLKGSRALLSFDPTFEAEPHYQLMKEMLMQIFGTPYHHPKSQPFIDHVFTFTVLDNRIWFRNFQIMEEDGSLVEIGPRFCLNPIRIFEGSFGGKTIWSNPHYVPPNKYRAALKKASAGKYINKVQQKVEYERTKPKSSYNLDPSDQIFQVEPEELET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEA9</accession>
    <name>A0A1D2NEA9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_03077</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000068">
        <property type="protein sequence ID" value="ODN03608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEA9"/>
    <dbReference type="STRING" id="48709.A0A1D2NEA9"/>
    <dbReference type="OMA" id="NLGMAMQ"/>
    <dbReference type="OrthoDB" id="37597at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03761">
        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000051">
        <property type="entry name" value="Proteasome subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 12 13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN03608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="34672" checksum="3A3504B15464A202" modified="2016-11-30" version="1">MALDSLCGFATGQPSFKAFSSMCTLQNDLDVFSGNFKNNLQLMNPPAAHIPELEAMKVDYKDPLHRERKTPYGFYKSPLGYGPMEVPDVGAATAPSPGGGVKIQMAHGTTTLGFKFKGGVIIAVDSRATGGMFIGSQNVKKIIEINDSLLGTMAGGAADCIYWERFLSKQCRLYELRNREKISVAAASKLLANICFHYKGYGLSMGTMIAGWDKRGPGLYYVDDDGRRAPGNLFSVGSGSTYALGVLDGSYKWDMTDEEAQELGRRAIFHATHRDAASGGVVRVYHVKAGGWEKISEVDNDKYWEKYSDQKMPIVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEX9</accession>
    <name>A0A1D2NEX9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane emp24 domain-containing protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_02878</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000063">
        <property type="protein sequence ID" value="ODN03820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEX9"/>
    <dbReference type="STRING" id="48709.A0A1D2NEX9"/>
    <dbReference type="OMA" id="GMVENDR"/>
    <dbReference type="OrthoDB" id="10037706at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905465" evidence="10">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="38"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="17037" checksum="6A66AADC7AD9E84F" modified="2016-11-30" version="1">MIFPIVLVLLLLQISQALYEDAPGVAMDYKVHVDAGKEDCYYQYVYPGSTLYVAFQVLRGGDGQAGFAVRHPNGNIVHPYVWKAQSDYQETSAAGGYYSVCVDNQFSRFASKLVNIYITTFRYDEWEKYTKELESLDISVQNFTGIISGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEZ0</accession>
    <name>A0A1D2NEZ0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Coiled-coil domain-containing protein 93</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03133</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000070">
        <property type="protein sequence ID" value="ODN03546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEZ0"/>
    <dbReference type="STRING" id="48709.A0A1D2NEZ0"/>
    <dbReference type="OMA" id="EVSHAEN"/>
    <dbReference type="OrthoDB" id="16092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039116">
        <property type="entry name" value="CCDC93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019159">
        <property type="entry name" value="CCDC93_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16441:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16441">
        <property type="entry name" value="FIDIPIDINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09762">
        <property type="entry name" value="CCDC93_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCDC93 coiled-coil" evidence="4">
        <location>
            <begin position="47"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="54"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="38384" checksum="E96681673CC778E0" modified="2016-11-30" version="1">MADCSVEKPASVDDKNVEKQDEFSNGAVGSDQSRPTVSSSGSGLELIDAVIAKNKQLDESLSKYDAEILEKEQTLQELQSQLEDLQTKSVTLDDEMKSLSESSSENNELAREIEKYLAIYERLKSDEKLFKASCNEELIRLQKELESLNTDSSDGTKTDLGTQLERSTARLEAGRIELAGINRKVAAIKRQIEQVPNRMELREYRLRFSELYNQVSATHRSTKQFFSLYNSLEDTKRYLEKELSLLNSIVDSYQLASTSASGREEFLRQLQSINEGMRESCSKVEKRYQIDKSAVETLQAEIQRLLDVKVAYEKCLLELEAECKRNEKLLAECKAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF65</accession>
    <name>A0A1D2NF65_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fructose-2,6-bisphosphatase TIGAR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02772</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000060">
        <property type="protein sequence ID" value="ODN03889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF65"/>
    <dbReference type="STRING" id="48709.A0A1D2NF65"/>
    <dbReference type="OrthoDB" id="430207at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="416" mass="46853" checksum="17BF5B440D933CBF" modified="2016-11-30" version="1">MAAPVALRLRGFIKDYPVVKGMVTYAVLWPVSNICQQTIQGREQYNFGEAARFCIFGTLVVSPSLYAWVRIAGRLIPGNSVKSAIKKALVEQVLYSPFAITLFYSGMSVLENKSLDELKSEVQAKFWPTYRTGICIWPVVQTLNFAFIKERNRVAVTGVVSFFWTVFLSYMKQKEFKRKTKFYTNVLLKIIANNSGETFMNSKRLLQGHTDAALSEIGIEQAKLLGQAITSTTFTRAYSSDLQRAYNTAKLVLSELKTPCPEIVKHANLRERSYGEAEGRPAQEFIEEAAKANISIHEYTPNGGESIQHLSKRVAEFFEELCTLSETTTSNENVLVVSHGGWIQGLMRYLHSDRNKYELKNFTPGNAIRIHFNTGLTVMSITPSPNENGTPKYEVNILKMNDASHLPKSLDTFHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF87</accession>
    <name>A0A1D2NF87_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Dynein heavy chain 7, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_02785</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000060">
        <property type="protein sequence ID" value="ODN03914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NF87"/>
    <dbReference type="OMA" id="FHDSPYA"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000002">
        <property type="entry name" value="Dynein axonemal heavy chain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000223">
        <property type="entry name" value="Dynein heavy chain 3, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001328">
        <property type="entry name" value="Dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000005">
        <property type="entry name" value="Dynein, axonemal, heavy chain 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF66">
        <property type="entry name" value="DYNEIN AXONEMAL HEAVY CHAIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="17">
        <location>
            <begin position="2240"/>
            <end position="2275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="2823"/>
            <end position="2878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN03914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="4024" mass="459403" checksum="6327D4AA83289513" modified="2016-11-30" version="1">MANRYADRAIRPFKLEDLFEDTRARDEGIKSDGAVRVATQCGGTGLGRGYSQQQCGAGDIARITNPAALIVRASDRGPEVVAEDLYTIPEGLFRQQRKRKGARIDSIHVMPSERKKKAPTTKAKEWAEAARKQEEFRRALVKLIHSMVPPAENVFPAEKIFHMMGDTFESDDGKIPKLDIVFDPNEKDLGELRYSFYIHNGLDAINIRPIESAWLNNIWRNVPLKLRHSYATLAASLSDEVYDEYRVAVKKAMIDFVLHEPDKHTQAQLDSGPRSDPMLRKVPKPWHPDVMKSKKRLLKHLHVVNPVLAYLHMVWRAVFSNLRYVDCYTLGEQKEAFTLRYYRDTTKHMIEDVRGLLLRKWIKGIQHTLIGAAKRNMVPKANDETRMKNFFNCVATVMQTNLLELFNESLEEYTNFMCCRLQLIHRPKFVVRFISHHNQLVPVPSFDDWEASVLQVVDNLVDVSNSFPRMEAKIFGNWDEGGEEGGALRPTIDPLKVIEIKKEISEYFRDQTKGPLEFVSAYNEHQFLFNGENEDMMDNFIGEERSWEQLVEEVKKFHALSQDVPVSYDPKTLIGIFDVHCDELIKGLANRAMEVRDKFLEKMIHELHALLKEIVDEYEAISEKALSTPTSTEQLFALKEEIEKIKEKTLPHMTQEVKMYLSRYMFIADYMQLSPILSKLQMQSIQWCNRMPYVLEEHYQIVAKKALEFQESLKLKRLRFLEELESYAKQVEEFQYFGDLEELPKYLKRAQALDAKLQAASDKADKFNREEEMFEYEVTNYPLRKQVSDKLAPFLRLYESASEFLEKKDLWLNSQVGTHDPDTIEGDTSNIYRIIFKLEKTFSDVPAARELVVQVKGLIELFKEKMPIITTLGNPGLRERHWEKISEIIGFPLRPSPELTLQRIIDMGLDEYIPKFELISEAASKEQSLEKNLTKMKSEWADMSFQIVPYRETGTYVISSVDEIQVLLDDHIIKTQTMLNSPFVKPFLEEMSLWEKDLVLLQEILDEWLKVQTTWLYLEPIFTSPDIMTQMPEEGRRFMNVDKTYRDIMRHAVNDPKVFSILKIDKIVEKLKKANDLLELIQKGLNGYLERKRLTFPRFFFLSNDELLEILAETKDPKRVQPHLKKCFEGIARITFTEDLEVTHMQSSEGEVIKLQGIINTEQARGAVEKWLVELEDLMKKSIQKEIEMSLEDYVNRPRTEWVIQWPGQPAICVACTYWTTLIHEAFNKGGTALADYLEVNNQQINEIVALVRGKLSKQNRVTLGALVVLDVHARDVLQNMVNLGVKNDKDFQWLAQLRYYWEGGRAITRMINSMLPYGYEYLGNTPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVGLASCGAWSCFDEFNRIDLEVLSVVAQQILTIQRGINSGARQLVFEGTELTLDPTCAVFITMNPGYAGRSELPDNLKALFRSVAMMVPDYALISEISLYSCGYVNARPLAIKIVATYRLCSEQLSSQSHYDYGMRAVKSVLLASGNLKLKYPEESEDILVLRSIKDVNLAKFLSHDLPLFHGITSDLFPGIKLPEPDYEQLNAAVFDNCNRMNLQCVPFFLEKIQQIYEMMLVRHGFMIVGYPFGGKTSAYKALAGALGDLCERGEMEENKVQICVINPKAITMGQLYGRFDPASHEWSDGVLAINYRAFAQSPTPDRKWLIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQLSPPCSLIFEVMDLEAASPATVSRCGMIYMEPETMGWECLLNSWLNTLPPFTPDQVKDCLKELYMRFCPTLLHLVRKGGLKELCPTTNSSLIRSATNIMESLMDEYKEEKYIKTFTMNTQLSRIEGIFVFGITWSLGASTDEDGRAKFDSLFKLLIKKKSEEDEKEEKDRKDKINHPTEGSIYNYTLIKEGPGTWEPWESEMKSAPNIPREMQMNQIIIPTIDTIRYTQLMKILVTHEKPLLIVGPTGTGKSVYTIDFLLKKLDKNVYRPLLMAFSAQTSANTTQDIIMNKLDKRKKGTFGPPVGKKLVIMVDDLNMPIRETYGAQPPIELLRTWLDHWLWYDKVDASPIHLVDLLAIACMGPPGGGRNPVTPRFIAHFNTITINDFSDASMIHIFTRIMMWHLDAKGFSKDFDPCVDQIIAATMHVYKSAMSNLLPTPAKSHYLFNLRDFARVIQGVLLSMPETIHDVPALKRLWIHEVLRVYYDRLIDDTDRGWLYEALQEIVGARLEEDFHELLIRLDTDGDGVVSEQELRSFVYCDFGDPKADQRFYNEVPSIEELRHIVESLLDEHNSMSKKQMNLVLFRFAIEHLTRLCRILKQPRGHALLVGVGGSGRQSLTRLSAHIMENELFQVEIHKSYGSNEFHEDLKVYLKKSTFTESHGVFLFTDMQIKEESFLEDVNNLLNAGEVPNLYPNDEKAEICEKMRAIDRQKDRSLQTDGSPVALFNLFVERAKMQLHIVLAMSPIGDNFRNRLRKFPSLVNCCTIDWFENWPEDALVAVATRFLADIDLTHDEREGCSFMCRWFHQSTERLSLRFRSELERYNYVTPTSYLEMISTFKALLDEKRSYNRGLKQRYEVGLEKLDHAASQVSVMQEELTKLQPALIEASRQVEDIVHKVEKESMEVAEVEKVVRADEAQAGEQAAAAMAIKQECDAELAEALPLLNGALEALNTLTTADIAVVKTMKNPPMPVRLVMEAVCIIKGVKPDNVTEPGTGKKIEDYWGPSKRVLGDMKFLEGLLNFDKDNIPLANITKIRQKFIGNPDFDPDKIRSASTACEGLCRWVTAIEKYDIVARVVAPKKQALAAAEASYSKAMTALEKKRAQLAEVQARLAILEETMAQTKARKMKLESDVQLCAKKLERAEQIIGGLGGEKGRWQQIAIDLGKAYPYLTGDVLISSGIIAYLGAFTSKYRDEQMAQWYDKVVGLNIPTSKSYNFNSTLGDPIAIRAWAIAGLPSDSFSIDNGIICSNAKRWPLLIDPQGQASKWIKNMEKKRNLIVVKLADNDFVRRLETAIQFGYPFLIENVMEDLDPVLEPILLKQTFKQSGSLCIKLGDSILEYNPEFRLYITTKLRNPHYLPEVAVKVTLVNFMITKVGLQDQLLGIVVARENPDLEEERIQLTVQSAENKRQLKEIEDKILEVLSSSKGNILEDEVAVNTLSSAKTLANEIQIKQAGAEETQKKIDEKRLEYTSIADYSSILFFCLADLAGIDPMYVYSLSWYVNLYCNSIDLAERSEVLEDRLENLKTHFTYSLYVNVCRSLFEKDKLLFSFKMCIQIMQALGKIDNGEWIFLLTGGVGLDNPHPNPASWMPNKAWDELCRLNDLPTYAGIKSSVESNPSAWQVMYDSNTPHLVPLPEPFQSKLTHFQRLLVLRSLRPDKVVPGVQDFVAQNMGQKFIEPPPFDLSKSFMDSQCAVPLIFVLTPGADPTAVLLKFAEDMGFGGYKLQSLSLGQGQGPIAVRLINDAVKNGSWVVLQNCHLAKSFMPTLEKMCEELTPETTHPDFRLWLTSYPSPDFPVAVLETGIKMTNEPPKGLRANVFRSFVSDPINDPDYFEGCKNAPAFKKLLFGLCFFHALIQERRKFGPIGWNIPYEFNETDLRISALQLRMFMDEYDDIQFDAIRYLTGECNYGGRVTDDWDRRTLTTILRKFYCEDVVNIEGFQLDPYGVYKVPPPMEHEEYLNYALAFPLVANPQVFGVNENADITKDQNETNLLFSSILLTQSKITGASGGKTPDQLVTEVAADILAKLPNDFDTDGALKKYPTSYSQSMNTVLVQEMGRFNILLVLIRNSLINVQKAIRGLVVMSADLEEVVKSMLVSRIPALWMKKSYPSLKPLGSYVNDFLARLQFLQDWFQNGPPSTFWLSGFFFTQAFLTGAQQNFARKFQIPIDLLDFDFHVLDDKDYPTPPEDGVYVYGVYLEGARWDREIKEINESFPKILYDSMPPIWIVPLLKKDLVPRPCYISPVYKTSERRGVLSTTGHSTNYVVKMMIPSQKPQEHWIMRGVALLCQLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF91</accession>
    <name>A0A1D2NF91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_02734</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF91"/>
    <dbReference type="OrthoDB" id="6489792at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.160">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN03938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="16758" checksum="0E765FAD16BE128C" modified="2016-11-30" version="1">MQSHGSFPGSVIFLQGLQAPICAPDSICGYLQANVRGINYQRLCACPSGFPSCPMSWDSDDGHSVTQGSDQYKFCGRHPSLTTCEQNQAAYSTRMEYSKSTDELFAKVDRLHCVCPEDHNYVLAHQNWGEADPDIEAVEFSYTCALVSDISC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFG5</accession>
    <name>A0A1D2NFG5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Katanin p80 WD40 repeat-containing subunit B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFG5"/>
    <dbReference type="STRING" id="48709.A0A1D2NFG5"/>
    <dbReference type="OMA" id="FNGHERN"/>
    <dbReference type="OrthoDB" id="10251605at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008352">
        <property type="term" value="C:katanin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000462">
        <property type="entry name" value="Katanin p80 WD40 repeat-containing subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19845">
        <property type="entry name" value="KATANIN P80 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19845:SF0">
        <property type="entry name" value="KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="4"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="47"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="123" mass="13073" checksum="921E4309779C3574" modified="2016-11-30" version="1">MEEFPAHAANVNSVSLGHKSGRVLVTGGGDKKVNLWAVGKPNCIMSLSGHSTPVDCVRFSITEEQVCAGSQAGALKIWDLETAKILRTLTGHRASIRCVDFHPYGDFLASGSSDSGIKVCMKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFL6</accession>
    <name>A0A1D2NFL6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Insulin-like growth factor-binding protein complex acid labile subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02623</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFL6"/>
    <dbReference type="STRING" id="48709.A0A1D2NFL6"/>
    <dbReference type="OMA" id="NTFEIMN"/>
    <dbReference type="OrthoDB" id="2020019at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF96">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905492" evidence="4">
        <location>
            <begin position="20"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="694"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="779"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="709"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="789"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="813"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="840" mass="95565" checksum="501801367C5D5264" modified="2016-11-30" version="1">MEKFLNILLLALYFSEGQAFPSGFSTDDCPPDCICYSDYLHNLESWKWVEPDVHYDSDDPEHESFNPYTEHNEVFDNPALYKKRQRESMLSTVTCMIRNNGTDTLENIFAYIPRTTQVLSLIQAPGSGSVILGRELFKKFHSLVGLEIQGYNEKEDLTDITGDSFEDLVSLTYLNLETVHLRQESVENRLHDPTSKILRINYTFNDVMTNEVTSQLLIISPDKDDDKESESIMPYSEYKKSTQKEKIAPLEPKVRAAFTGLPKLQHLRISSCSLYDISWDIFYKLDNLKYLLLDENDLLFLPDFVFYATSNLSTLSLSRNRILNLQTVGLAGLLYLQKLDVTYNNITHLSELSLPPFPHLEVADFRYNPITSIFPNTFEIMNSTKTLYLGSPTTSLDLSPNSFYGLFSLTKLDIVNVKIRLLEKTMLKGMPSLKTLIMTGDIPRISYDAFGEVASLEKLVMRNCGVRKISMDAFFGLTSLIELDLSHNSLSFLPPGIFEEQTTLREVFLQHNQLTTLPVNLIENLPVKLIRLEGNPWHCSCDMKSWNPQQINRVKRYHIPPPNNPLCQKAYDKGSMCFETYEPKFEVTYSYEKRVSPVCETPSRFSKRSVFQVLRKELKNCAKTNDKPKMVTDFLSFPENFSSDTLKAVETQLLIKPSKIKKPKPGKTSLSNSDGILDPINDISNTITAFQFNQDPDKTTKARKPTKPTKPTTPIPKLTSNQINNVNVTEENEIPKLNTLANIVLTNEPSNSIPETLNPTPIPNPIQVPVVPTIDPVEVPPPAIVTSRPKSKSNRSNEKKKKNRHSKNREDVTNTNNQNTGPAISNKAMKLLRQMRQRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIC8</accession>
    <name>A0A1D2NIC8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000035">
        <property type="protein sequence ID" value="ODN04835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIC8"/>
    <dbReference type="STRING" id="48709.A0A1D2NIC8"/>
    <dbReference type="OMA" id="WERERMC"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="72"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="242" mass="28727" checksum="6D9617564CA0EA7D" modified="2016-11-30" version="1">MAEPTPEEIKVIQKFREQVSDVLDNEERREDSFLIRWLRARDMNLHKAGELIRHSLNWRAENDIDNVLERKFDEFYFQHFPYSAEGYDKTGRPVTSISYANGKWDFRKVDEPDRAEGFKAYTAYIFEDIVNKIRMQNAKRKTTGEPPVRQYILLIDYTGFTYSQLINFAAHYPELLYKCIFINCPGFIGTLMSLLKPLLANKTFQKIEYYGYNREEWENVLYEMIDEDQLPPEFGGTEITHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ44</accession>
    <name>A0A1D2NJ44_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Vascular endothelial growth factor receptor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_01743</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ44"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ44"/>
    <dbReference type="OMA" id="IYPNDYD"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000554">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000586">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF600">
        <property type="entry name" value="PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000615">
        <property type="entry name" value="TyrPK_CSF1-R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="608"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="686"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="839"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="693"/>
            <end position="700"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="715"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="843"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="844"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="857"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000615-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN04986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1028" mass="116053" checksum="B8E9742D6DDF5D6C" modified="2016-11-30" version="1">MKSHHRNPTLCSAIVAFTLFFNVANFILTAHCDELLPKGENENEFAACLKSPEAVLIECHVVNVVKASCVEGVPHQPNVISIPQVPENGQGEINCTSPTPLELSFVGFQLEDFVTTKYVRNAANVFNEATYVFSVSFPLSQITSSRQVVVSRYNSEGQKMSFFLFRPGNKVFSSNVVNTNNSSEAIPLEFSDKRGVIPCVSNDPTVNPRLESVPQFGGPEDYQVTSGFIINSTGANAGERYRCRANVSTTTNPNTYEETAFFEVQPRRDAIFQPQTDKVYLFSNSELRISCKYNKRVVLEGNFKSKPITSKSFFSTTSLLEAESEYVENIVKVGDSGTIKCKSDDGRDLKTWNIETLDINNNPVVQLKKTSETEITCESKEFPIDKLKLQVVFCQGISECKLNEFCFDKEKGKYCGNYVEGTPCNHSSSTKFGGGLPSNNNQSSLCVSLPQNASYLSQGMIRCSAGEHTYQTNYFRGFDKKLYLDWTTAPVSALIDIFVPNVTMYPHNSYPFGCRATKFISDGTLQWVIRGKDGSEILLHKNRVQDLRDVYASDLDYKLYTVRESNIRLIYPNDYDVICMVPRWNATAWVRHHKRINVAAKEAPVTEIVSVSVSVILVLICIVVYVMWRLKKAKDAIRCLTEKEVQEFLEGNPEALKNATNKDAHEVVDSLPYDKKFEIPREKLLIDTENCLGKGAFGTVLKGRVEGISDVVAVKTVNNDCEVNRFKGFLSELKIMIYIGRHPHIVSLIGASTEKIKEKTLYIIVEFCANGSLEGYLRKYKNRVLDQRQEGNAYENLNTPSVSTESNTDKLTTAELIRWSYQTACGMEYLANKKVVHADLAARNVLIDARGNAKITDFGLSRQLFDYAQYVKKQQEPLPWRWMAIESLQQLRFSTHSDVWAYGILLWEIFSIGDIPYPGLSWDIQFVHQLCDGLRLSKPYHATDGIYNLMLDCWQDIPDSRPSFSFIAQYFKSLLESMNVNLEATKEPQPMSEISYINTLTPGYMRVAELLEVDTTDSRRSTNIYINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJI3</accession>
    <name>A0A1D2NJI3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UNC93-like protein MFSD11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01249</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-93 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJI3"/>
    <dbReference type="STRING" id="48709.A0A1D2NJI3"/>
    <dbReference type="OMA" id="QFQDKTH"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17407">
        <property type="entry name" value="MFS_MFSD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF0">
        <property type="entry name" value="UNC93-LIKE PROTEIN MFSD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="508" mass="55716" checksum="CF865126E9AF89E8" modified="2016-11-30" version="1">MRFNFKRLVLRVPKFVLSIASKAREFQFRYTRLPTTEHISVPLKTNPDCVDMAFGCCSMDIQFQNVLLLSFSFMLVFTSFQTMGNIEQTVLRSINMDEPSFTGNGYISLSIIYGVFSISNWVAPSIVAVLKEKKSMLAGAVLYTAFIASFLYPKTWLLYLMSAVLGIGAAVIWTAQGSYLAICSDETTMSRNSGVFWAILQSSMFFGNTFVFFAFDTKDESAKIEESTRILVFSVLTGVAIIGVICMLFLRTPGRVDRTVPMLDIQLPEHGAVAAFKKSLKLFTKKEMVLLSFTFFYTGIELSFFSGVYSTSVGSTEALGTIAKRLVGLSGILVGAGEVIGGALFGLLGARTVKNGRDPIVLLGFLCHTVAFYMIFINLPDASPLGSTGGLSYIKPPSAVIAMICSFLLGFGDACYNTQIYSILGGLFPDDSAPVFALFKFTQSAAAAASFYYSSLLTLRIQLGILQIFCFIGSFTFFLVEWASVQKKIAATSCAEEDPDDEYRIDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJR5</accession>
    <name>A0A1D2NJR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJR5"/>
    <dbReference type="STRING" id="48709.A0A1D2NJR5"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="27694" checksum="D17111287DC03F4F" modified="2016-11-30" version="1">MFSSTAVEEGQDDKDDKNIKGSKSVIGTNQNGDRDTNDTETQFKMSTEFKHTERDSPSPLTSPRKDCESRASTLTDVTNSHSASDCQSCSCSVSGSGSESSGSENEDGEKRQDDFDCRGTYKPYYSYYDDYPRRVRSQSLDFASARRELRRRRFSENHEWIRGENKQKIKEEPKKEDEPKAYTIYESILQEMGRRGSLHGHRPADVALDPAHAAILFRDSRGLPVADPFLERILLLSVCSHNQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKF0</accession>
    <name>A0A1D2NKF0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Glutamate receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_00942</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Postsynaptic cell membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKF0"/>
    <dbReference type="STRING" id="48709.A0A1D2NKF0"/>
    <dbReference type="OMA" id="VMPPSTH"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022824">
        <property type="term" value="F:transmitter-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13715">
        <property type="entry name" value="PBP2_iGluR_AMPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000105">
        <property type="entry name" value="Eye-enriched kainate receptor, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000087">
        <property type="entry name" value="glutamate receptor 4 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000001">
        <property type="entry name" value="Glutamate receptor ionotropic, kainate 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001508">
        <property type="entry name" value="Iono_Glu_rcpt_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00177">
        <property type="entry name" value="NMDARECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="9 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0628">Postsynaptic cell membrane</keyword>
    <keyword evidence="10 22" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0770">Synapse</keyword>
    <keyword evidence="4 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="693"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="20">
        <location>
            <begin position="300"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="21">
        <location>
            <begin position="310"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="553"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="603"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="site" description="Crucial to convey clamshell closure to channel opening" evidence="17">
        <location>
            <position position="532"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with the cone snail toxin Con-ikot-ikot" evidence="17">
        <location>
            <position position="559"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="616"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODN05740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="745" mass="84415" checksum="BF9AD6F55A929A58" modified="2016-11-30" version="1">MATIMMAITVRGTVGSRNITRVQSYVWIHQVFCHLLEMAYEPEQGVRTAIICLIKRFHFKRLWGSQERFTPKYVILDCPAALAQEVIIQHVQGVQMGRRTYHYLLSGLAMDEPWESSIVEYGAVNVTGFRIVDPTRRYVRDFLKKWTQLDSTNFPGAGRNSISANAALMYDAISVLGEAFSKMFKKKLDFLQTGTNGFRPNGTRDVHCATGGDFTGSPPPFENGEKIAKFIRKVEMEGLTGDIRFTEDGRRHNYTIDVMEMTIHSSKVKIAEWSDTRGFMAIPAKYIRPPTFSRIQKNRTYIVTTILEEPYITYKVPENGEILSGNDRFHGFCKDLADRIAETLGIQYEIRLVKDDKYGNEDKNGEWDGMVGELVRREADIAISALTISSERERVIEFSKPFMSLGISIMVYKPKKHSPGVLSFMSPLSNEIWLCVFFAYIGVSIVLFLVSRFNPNEWKVETNGLVNHVSVSNDPMWFSLAALVQQGSDISPRSTAGRIVASVWWFFILILISSYTANFAAVRTVNRMVTPINSAEDLAAQTEVEYGTLDRGSTWNFFKRSQMQAFSKMWDFMNARPHVFVQTYAEGINRVREKKGKYALLIESPKNDYTNGRKPCNTMKVGRNLDAKGFGIATPLGSPLKHQINLAVLSMKESGTLMQLQNKWWVDRSECPAEEKGAAETDDELSFSSLAGIFYILILGLVVALFVAAVEFCYNSRKEAKKSQQTPYRATFLLSRVVKVENELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL14</accession>
    <name>A0A1D2NL14_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nuclear RNA export factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00894</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NXF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000016">
        <property type="protein sequence ID" value="ODN05805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL14"/>
    <dbReference type="STRING" id="48709.A0A1D2NL14"/>
    <dbReference type="OMA" id="YGGHEAW"/>
    <dbReference type="OrthoDB" id="25872at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14342">
        <property type="entry name" value="UBA_TAP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000018">
        <property type="entry name" value="Nuclear RNA export factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000004">
        <property type="entry name" value="Nuclear RNA export factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005637">
        <property type="entry name" value="TAP_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015245">
        <property type="entry name" value="Tap_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22602">
        <property type="entry name" value="NXF_NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09162">
        <property type="entry name" value="Tap-RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03943">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00804">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51281">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="9">
        <location>
            <begin position="459"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="TAP-C" evidence="10">
        <location>
            <begin position="661"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="715" mass="80454" checksum="8F4F4DB56D498614" modified="2016-11-30" version="1">MPRYNNDGRTAKFLHTGGGGGGGGRGGRGGGFQDNKKFNDFKFTVQQNRGGIQKKHKKVFQRLDDAGDVIMGGEPQPGSSGQGGHRRNNRKNRDWKNKLGKSTKHNDFIFGPGWHKVTLIDGTSYSKDAVLSMLLATCRTPFTPIAYSVIGTNTVFFVEERAVAQSLAECNDKITVAENQTLKLRIQPCGFPPTANFDTACENKVQAELELRFQQHTMTLDLSNFLMSQGLIREYFLPLTRASVVMKIFGLLESMLNTLVGLDLSNNKLVNLEGYGILLKKTPSLRALNLGKNKFRDINVLDKLHGMQITEFILEENPVCNNYTEKDKYISTLGWALTPDYPPIFVLPDRGVRHRYPYQSRAVAPCLIAYRIMNGGPLMKLSTFKINSNQEVIGSYLHYVSLKRDLSLIVRSDVRKRFPKVTKLDGVDIPPPITFEVSEPVKMPEVRASSFCNEEAKKVVLAFWEQYVMLYDSNERQPLIQAYHETAAMSMMASYSQQGHVSQMDPSKKLSVYIGDSRNLHRQPDKHRKYKLLHQGKQDIIEFLQRLPKTTHDVASFVIDMPVAVENFILFNVIGLIKEREERNQPIRYFSRTFALVPLNGGFVIVNELLYITNPTTEQIKGAFKAAPITANAVVNVNPVPAAVQGPSTAVAALSRAPTEDEKRVMLASFSQQSGMNEDWSRKCLEQNEWDFNRSAVVYSQLKEQGKIPPEAFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL48</accession>
    <name>A0A1D2NL48_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL48"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="184" mass="20942" checksum="776C076CA940B280" modified="2016-11-30" version="1">MVQFLPLFGRNSTSCLEYYTIIYMLLIVSQMMLDAAYFQTIINAPIDSETPINIYKCIIIPVHCLQATLQFFFGFDLFKATIKRSYRRAKNWQMVFLCLLAIEVSIFLAYIALATILSVFTYVTACALVFKLYLVWPLRIFMEECQDVCVPLAHAASTTYLVDQEAQARPGPSTSSANKPITSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLR9</accession>
    <name>A0A1D2NLR9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ciliogenesis-associated TTC17-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLR9"/>
    <dbReference type="STRING" id="48709.A0A1D2NLR9"/>
    <dbReference type="OMA" id="LIPLWFE"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22973">
        <property type="entry name" value="DD_CATIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048777">
        <property type="entry name" value="CATIP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047501">
        <property type="entry name" value="DD_CATIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15505">
        <property type="entry name" value="RIIA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15505:SF4">
        <property type="entry name" value="RIIA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21772">
        <property type="entry name" value="CATIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ciliogenesis-associated TTC17-interacting protein N-terminal" evidence="2">
        <location>
            <begin position="160"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="571" mass="64378" checksum="06EB7A3EF44DFFA8" modified="2016-11-30" version="1">MSDDDYVDSLSSGIADITLDTDAKRDDEEEEEETKQAESTGFPAPEENEEPSNPPQPSNNEPPGKKGANRAITSPSKASGRTSGDKSGLTPTKSRTKSKVFKVLKAPRARSVDSVELLDPEEEKLKMLPDCCEFVKKNEGYEADDTRKEMTSAWFSRIKLDAAQEKQICFSESLLMVEENGAVVGKMYCSVAPSKWCDKPCICVHAGSFAKFPTGLESGTTITSFVNSKLKPHQELVHEWATLGANTLERKTFMISEGEHMPCKITMIKNGRTVDTKAVSLGFIEMESLVTEATNIILQRLLIQEKRTNGNMNLLSLSYTGKVVKAKYSELGSGWENVKGKQMKTWGIRRTVFVSEDEERQWDSLFNKHSRLILRCQPDSPQALIPLWFESIIDFDKHGNFTGLYSPYAWACDVELYSKYAVKKEEITHDHRRYIMDHPEVRALLSDYLQAVLFRKPQDIISFTKHYFQAFLTLRGRSTKPTAHKDLSKLSNDSYYDSSLTLSGEFGEWLGEGEDDDRNFYPINPTVDYDGLEKVDDEGIVNLSEGEPGVYTENETEDDLVVNEEGKYVHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLT2</accession>
    <name>A0A1D2NLT2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000008">
        <property type="protein sequence ID" value="ODN06248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLT2"/>
    <dbReference type="OMA" id="YAKRTHI"/>
    <dbReference type="OrthoDB" id="10636737at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="189" mass="20846" checksum="DC247F6EABF37653" modified="2016-11-30" version="1">MSVTELQVIHRHVKPTPTSNNRFLLPNGGDQEDTGLVMKLDSKLKEKIMLGQPTTTTSSPVVSMQNPSAVRPSAVSSQLCGQSHEVTGWVLRGALILQTAHIPFIKLTHKMNDTIQKKTKLLLPIVLYMSLLVLVAQAGAVVMLFYQSFMPIGMWFLLCCIAILAAMFCYTAVLSNNQSQSKASRFILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NML4</accession>
    <name>A0A1D2NML4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein still life, isoform SIF type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NML4"/>
    <dbReference type="STRING" id="48709.A0A1D2NML4"/>
    <dbReference type="OrthoDB" id="8059989at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043537">
        <property type="entry name" value="Tiam1/Tiam2/Sif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46001:SF3">
        <property type="entry name" value="PROTEIN STILL LIFE, ISOFORM SIF TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46001">
        <property type="entry name" value="TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN06335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="68" mass="7694" checksum="586632B843DCB9AD" modified="2016-11-30" version="1">MINQSKSRSVEAAPKHLIIVDGAIMQPIPEHPKRDYIFCLSTAFGDAYLFQVKLFNVELENTSEKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMT0</accession>
    <name>A0A1D2NMT0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NMT0"/>
    <dbReference type="OMA" id="SSTYKGW"/>
    <dbReference type="OrthoDB" id="10693050at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1460"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1537"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1566"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1664"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="970"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="983"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1244"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1267"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1346"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1373"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1388"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1479"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1591"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1664"/>
            <end position="1677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1678"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1701"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1757"/>
            <end position="1769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1792" mass="199826" checksum="83CA6D81344D0E37" modified="2016-11-30" version="1">MVELLVRKTHSLKNPKVAYFDKVEKTEGEFLSPSLEKREMERVLDLGTGVCNLHSFHYRPEKEFIVRRSEKQFEKKEWDHLHFKRLHYTRPSPTLKNGDDDDNDDDIPEDGFPTTSPQTPRHHHHHHHAHPNMLAQHSRQPHRSYKPHHRLHLPLLGGLHRHPPNRHHPHHHPPQHGHNSHHGHHHGHHHPQHLVQQQQQQQPSRQQQQQQLQQQQQQQIAQQQQQQQIAQQQQQQQIAQQQQLQQQQQQSQQSRLPPNQGAVNSYANPVKPQTPVFGFPGENAQAQAPTAAAPPAVKQPVRQFPTQHPNPNFFHQDEIPFNEQVSELPSGFSQPSTAPVQQTTSAYGPSAHGDNSPHGYLSSTYKGWKPIAKPYQNSYPRNPEALGPLPDFPPRGPQDFPPRGPQDFPTRGPQDFPQISDNHLSPFPDRHPMQDFPSGPSGPPPPQDYPTGPSAQQNGPPQDYPRGPPENLMEGFPNIPDPPQIPNFSQGPPENQLMDFPQQNHDSHLQGNHLPHHHHGPHGPHHHHHHPPRHQQHRHPHHHPHNHNHQHHAPGQQLLFHQPPPNQDLFLQPSSTPRDQFEFLPTGGPAPMDDFNNLNTNTLFRENIMHMKPHSRPAHHPQQQQQQSQQSQHPDHSQDVLVPLPPEVGDSVRLPNSLFTDNSWDQHKQPFETSQSEENVVVKKPKFPKLKFQGGGGGPPQNSNPNSEEGVEPPPSVFPKFKRPRLNKNKIHNQHQNNNDGNSDKHNGNNLNDHEPENDGPPKISQSSDENISLPPINLKNKLNGGRGRVRIRTRLRRPNPFQNSEEDDGPRGGGGNGGDEEQPRQRPGSEGGRPFPPFPGRERLRPGFRKHNQHNNPNPENNESKETPGPGPGIGGGFGGHDDPLKSNSEEEGPPPPPDFQSSHLFPGRQPDIFRDFPQAGPSQPPQENSKEKERHERIREPSRQPGRPFGIRGNIGSGERQQDQPENHSPPEPPPPPPPSHRPHPGLRRRRPKNQQKQNQQNQDHDHQDQNQDHREPPNHSEKPEPPPQVALNQNPLFSDEFFFPPGFNSDPSKNQHQGDNPVSFISMPNAKTQVIHHNAFSSQEQTPHHQPPTVSSTPQHHNQHVYPGNNNNFHRPQHQHQPQQLHYDGIDNGGRSPNFGINNSPFTRHHQPPHGVQLSAYSDHLPFTRGPPRGRKPPPLGHPPSKAPPPQQQAILNPYSFPATGPYGHPGGIAYDMDNAPQTLNSYEVPDGRPVVFLQQPGPPPHQQLPPPPGPTTPNGQMPVPSPLPPPRHVEPSPSPSPPPPPVQNIPARGRLPGGRHRKPAVIAAPVDPLGQSAEFEQIPAQYIDPAALNPEKQGAAPDKADGPGKDHDEEISQSNLRMNVVPSPKSRTANSSTITTTMSTEDRDRRADPRKHWSKLKNKDGKSSAVVVAGESPSSSEKIPEKKPLGRFTNKNHLKAKIADIARKNFQNHLMAVTGDGNGEESPAVTTYKPSLVSSGVNSSSHGNPEKSSAKASSLSKETILRVIPTWNSEDDLVDANIPKTVRFSSKTDGGPILVRGGGNKNDQQDHDGTTILFKSKRQFRRKRPGAGQKKAASFSPLTASTGDHDEGVGHEHNHQDHDNAVLSSNRPNHDDTNLLHTNKVSEADDGIGDGSEPTRVGVLRRRKLFPRRKNFSLSNKIKAGISSQSPKDSTTTPEASETEPVTYGESQWFRVKKFESQEKVEGKDLDDHNGGVPVLSTPVPTPESKTVPDADSEGTASSLSPVVLAAEPSSSRNKKTPTSEPTKDERPFGKKSSKFLMNRLSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NN78</accession>
    <name>A0A1D2NN78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sex determination protein fruitless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_00293</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000006">
        <property type="protein sequence ID" value="ODN06396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NN78"/>
    <dbReference type="STRING" id="48709.A0A1D2NN78"/>
    <dbReference type="OMA" id="HHNISEH"/>
    <dbReference type="OrthoDB" id="5560627at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN06396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="17057" checksum="0A781D3EBE782912" modified="2016-11-30" version="1">MNLTGQGSFPPRPCFIFEAVSPTSSERGPSSAERKRCRLCGKVVSNDYQHYRVHFPGNYPCQICQSLFKRKDYWKTHMRKQHQVAFPSAAESKEKKESSSSATVKVEKESSSHHNISEHLQSHSKDKVRERGSSSSSHHQHHPHGGGVDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0R4</accession>
    <name>A0A1D2M0R4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zonadhesin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008290">
        <property type="protein sequence ID" value="ODM86555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0R4"/>
    <dbReference type="OrthoDB" id="8288770at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012452830" description="Zonadhesin" evidence="1">
        <location>
            <begin position="16"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="50820" checksum="7ED05B32CFAC64E6" modified="2016-11-30" version="1" fragment="single">MKAFIFVALVASVAARSLDLDTLRLAKERTLLQREIGPTPPVEKTVVGDVIDRVLPVEQKQLLVDGQEQLLRGIYDVDRVLTFEEIYNTELFREYLTIPLFREYIKYPVFQSTSTHLSNSSPASTPFHTNTNNKLMDKMCMVNKTSFGRQSYDDLIVRNKNVLPYVYGQQQQDVISRRYEVPTFAGQYYPTTQGVNYKFLLEKLIKNLYVNQPTVGDVTQVKTDVKVFPTTQKVVIEPITGERKIVEEPKVVDVKVNEQIIPVEQVVAQQLPIERQLTREQLIREQLIREQLPVERQLTLCERQQFPVVDTVERQLIREQLLKDLVKEKYLTPEVYQTIARDIPTIVRDIPTVTRDIPTYTRDITREGRQTLFDIDTPVVGRREVYTPYTNRVVQGDRYNLINKLYNQLYNQEIPSIRENTVFDRLPLQQVLGNIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M144</accession>
    <name>A0A1D2M144_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone H3.3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007649">
        <property type="protein sequence ID" value="ODM86685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M144"/>
    <dbReference type="STRING" id="48709.A0A1D2M144"/>
    <dbReference type="OrthoDB" id="10256681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="137" mass="15577" checksum="D05B52681CC34734" modified="2016-11-30" version="1">MARTKQTAVNLLEVKLHVNNWLPRLLVRCPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPIPTSCSGFEAYLVGLFEDTNLCAIHAKVTAKGHSAWQTYPWRTCLNVLQPSNMKYGTTLIKSLISAFLRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1J2</accession>
    <name>A0A1D2M1J2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007062">
        <property type="protein sequence ID" value="ODM86828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1J2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903374" evidence="1">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="96" mass="10767" checksum="9C961848CE8BF2CD" modified="2016-11-30" version="1" fragment="single">MAKSLYLLALAFIASSEVVYGIEEWTIGNFTKQDAVNPVMGPRDNTTFLCSVRQEIVNWEKKDVFNPTALVRDAGTSDDLINWTPVVDPNEESEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M230</accession>
    <name>A0A1D2M230_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polypeptide N-acetylgalactosaminyltransferase 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19666</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006447">
        <property type="protein sequence ID" value="ODM87016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M230"/>
    <dbReference type="STRING" id="48709.A0A1D2M230"/>
    <dbReference type="OrthoDB" id="9982049at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005112">
        <property type="term" value="F:Notch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008593">
        <property type="term" value="P:regulation of Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000195">
        <property type="entry name" value="Polypeptide N-acetylgalactosaminyltransferase like 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF63">
        <property type="entry name" value="POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="4">
        <location>
            <begin position="393"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="527" mass="59956" checksum="88E68C70BF53F971" modified="2016-11-30" version="1">MRTGKRLGGGDDEKISALDSVGLIRTLQDKKVREKGYKKHAFNALISERLGFHRTRVTSNVPLRLILGLGASISFRYHLLLFNEEYNALLRTVHSVLDRSNPDTLHEIVLVDDSSDLDDLHEKVLERIFQPKSLFSRLQAELGLSERGFLELDMQQGRASFSGFPRRAKCIRCLTRIHENNHTVVTPVIDIINADTFAYSASPPGERGFQLGTPLSVGPCAKIRTEKGGRLCEADIKSNDGGGLFAMDKQYFTELGEYDEGMDIWGGENTEISFRIWMCGGRLEIIPCSRVGHVFRKRRPYGSLSGVDTTMRNSIRVAEVWMDEYKEKYYKTHYEAKGMKFGDISARVQLRERLHCKSFKWYLENIYPEMLKDEKGGGALYERNPRLPRNYIEKFLLRLSHTNYCVESAKEVNQQHTGLILGKCANFNKKKQRWSETERHELVLAELLCLDAMTDVPKLKKCHEMKGTQEWKKAGEKETPIYNLASGLCLGVQGMPELGSVVKMVICDETAGNNLLKFDMLSPDDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2L1</accession>
    <name>A0A1D2M2L1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">39S ribosomal protein L41, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005903">
        <property type="protein sequence ID" value="ODM87207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2L1"/>
    <dbReference type="STRING" id="48709.A0A1D2M2L1"/>
    <dbReference type="OMA" id="CQQRTIS"/>
    <dbReference type="OrthoDB" id="408933at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="123" mass="14398" checksum="E9C189D849212B33" modified="2016-11-30" version="1">MEGKTASWDPIYTEVKASGFHYDGVYHKVPEMIPDIILKPYVSYKTADIYQTEFTPENLFESVYKNKIVRDFKNNKLDDQGNPLEPNEMEKLTPEEAWIIARKSGSDIFSERTPKFWNAWTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3L4</accession>
    <name>A0A1D2M3L4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alkyl transferase</fullName>
            <ecNumber evidence="4">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19119</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate</text>
            <dbReference type="Rhea" id="RHEA:53008"/>
            <dbReference type="Rhea" id="RHEA-COMP:19494"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:136960"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.87"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01005053">
        <property type="protein sequence ID" value="ODM87563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3L4"/>
    <dbReference type="STRING" id="48709.A0A1D2M3L4"/>
    <dbReference type="OMA" id="YWPAFRE"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="291" mass="33761" checksum="CB13F409BA5B768F" modified="2016-11-30" version="1">MMAASETLLEKLFRKILQQGSIPNHVALILDGNRRYARENNMQTIEGHRKGKNTFKKLVNWNAICGVKEVTVFAFSIQNFNRSTQEVNDLMALFRSTIHEILGNKEIMTNGRVQFIGNWPLFPKDLKPLISKLMVDTRNNTKITVNIAFAYAGRDEITSGVKNLLHGVANKALTLSNVNEDLLDKSLQLYSMSPVDLLIRTGECRLSDFLAWGSSDHAVICFRDEYWPSFTYWGLLECVFYYQANKFRIQQDFQEEEKNYQQSWKFLSMLKKGLWKTVENHDERQRNFGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4G5</accession>
    <name>A0A1D2M4G5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Platelet-activating factor acetylhydrolase IB subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004618">
        <property type="protein sequence ID" value="ODM87824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4G5"/>
    <dbReference type="STRING" id="48709.A0A1D2M4G5"/>
    <dbReference type="OrthoDB" id="505607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852:SF0">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="28589" checksum="9A3AB9FF7DE70CFE" modified="2016-11-30" version="1" fragment="single">TTGKQIWDAKYAPLGAINYGIGGDRTEHVIWRIDNGELDGLRPQLVVVYIGSNNLPTHSNNSEIVRGVDTVITKIHEKVPSANILLVGFFPRGDMNPVSDLLRRVISISDTLEPMPCSPSLDRINEELYMGDKLHLNLDGSNLAQNPWTPQIRNEQWWLDRHQQILNSTASLGSQIKIVFIGSSLVENWANEGRPVWEANYAPLGAINYGPWRDRTEHVLWRIANGELDGLTPKVVVVYIGSNNVPVNTVDDIVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Q4</accession>
    <name>A0A1D2M4Q4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004314">
        <property type="protein sequence ID" value="ODM87967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Q4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903462" evidence="1">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="12741" checksum="691960726EA053C0" modified="2016-11-30" version="1">MCLCADLIGTIIIIIMGAVGKLDDVETASILSTSPTDIPHEGLKLKRETSQGSILHGCPLGRLTRLRPVCQSKVFEEASSPPHHPVFQQRPMMMMMIVPIRSNTFRISWLSTNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4V6</accession>
    <name>A0A1D2M4V6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-tocopherol transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004282">
        <property type="protein sequence ID" value="ODM87993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4V6"/>
    <dbReference type="STRING" id="48709.A0A1D2M4V6"/>
    <dbReference type="OMA" id="IREETIH"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF130">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="78"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="272" mass="31392" checksum="8929DCEE154A6FF7" modified="2016-11-30" version="1">MENVSEIIYEQEQFIPRLTEDVRNSLRENYQLSIPNECTGFIVRCLRIKDYDVDKASKLVKNFARSTHQLRDILEKFQPKFYKELYLNGLFTVLRSRDALGRQVLIFRLGKVDPKAFDFDETSCAAMLLFSYVVGQSLETQRKGIIFVHDLTGFGIQHVKSVKPGRLTQLIGLMQDGSPGRIKGVHLIFHPKVFGLIYHIVKPFLKEKLAKRIHFHGDDLTSLHKYLNPETLPKSLGGIHEDSQCYDLPLLHKLIREETIHKELQAYSVPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5N1</accession>
    <name>A0A1D2M5N1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003951">
        <property type="protein sequence ID" value="ODM88221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5N1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="184"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="33271" checksum="4BF6CCE21E825DEC" modified="2016-11-30" version="1">MNLFLLENYSTRLQLRRACTNTANGTASVFLFDQEMSPNGKGKLKEGRFPWKVYQVPESPGVFGFKLHISFVVTKSITDTEGKSTPAILETEVGEMRAFLQEDGAIKFLASGNIDASAAEIMYFSATGGYRNPTDILTLTMELVNQTSMTPSLSATPNALQELMRASSRKKSNLILFSSLKTEAHCPAFENMFKTNTNLVQQSRHQLSLSEEGLKALLDFVYCLKLDIPKEKPGVALALLEIGIKMQMPMLTKAMNNLLVEQPDDWLKFDAALQLLLHSTKMRGYEELKNKAIRAMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5R3</accession>
    <name>A0A1D2M5R3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003771">
        <property type="protein sequence ID" value="ODM88315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5R3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="176" mass="20020" checksum="7D53F8D2ECB4C1DB" modified="2016-11-30" version="1" fragment="single">MANLNGAKRVKVFKSSLDPIKIIGEQFHKITGEAANQDVLMSANALQCFLRCSILMEYIPFSSFATSRCKSTAKSLITEALETFQFARWILDVDLQSSGGGRHPLHANESRIKFTSLPYCLKTRIFNTPQLLSRFLNRTSWSEVGDSYHISNAFLTLQITFTIDTPFQYKRTLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M610</accession>
    <name>A0A1D2M610_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mannosyltransferase</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18335</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01003736">
        <property type="protein sequence ID" value="ODM88344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M610"/>
    <dbReference type="STRING" id="48709.A0A1D2M610"/>
    <dbReference type="OMA" id="HHMVFNN"/>
    <dbReference type="OrthoDB" id="416834at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF4">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 8 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM88344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="512" mass="58071" checksum="F4D8B21ED311C721" modified="2016-11-30" version="1">MEVKNLNIIIVRFNHIYMRWEAVLAVLAFKLLVSLGISLTTEFVPDEHWQSTEVAYTLHFGHGHLTWEWYANIRSYIPPVVILSLYKIGSLLNCDGNSIILLWLPKILQSLLTLVGWHYFHKFATEVMSKAGNVAGGLLLISWFTSFCGARLISNQTEMSLNCIALYWLVTDKLVPFSFIMGLNFAMRPTAAIFWLPFLPSFFPVKTKTVKYFLKCLIFAALPLGAALALDSQMSGSLSPTWLEFFKFNFLQGGSAEFGIHSPAWYFYSGLPSILGPFVVLLPLGYFARETRPLTNALTFYLILYSFIPHKEIRFLLPAAPLVFTICGSVINSVLYEKKNNTSRMAWFLDKCLKTGIVLFIALNLGATIFLGFYHQRGVKPATTFISQQISEMDKPRVWLLAPCYSVPVHSHIHHPNVELQYYICAPQQFRQLYKDGAFIQPNGFSTVDLEADITNKLTTAEPPHFILAFGEYVPKILKAFEKNDLSYHICQSYAHTDVGDFARTVEVLCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6M8</accession>
    <name>A0A1D2M6M8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003367">
        <property type="protein sequence ID" value="ODM88629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6M8"/>
    <dbReference type="STRING" id="48709.A0A1D2M6M8"/>
    <dbReference type="OrthoDB" id="10057873at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16520" checksum="DF1EC14E36678CD4" modified="2016-11-30" version="1">MDSKGHEAKRNEIKTLMIREALKFYKPLDCAKRSEVNAWSDLICEDAEQPEENTDAESAVELECLKYLQDSADSIAGLTAYPTVKSMSVKLNTPLPSSAPAERLFSYAGMVLRPKRSSLSDELFEQLVLLKLNFKPPINYSNFVSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6U6</accession>
    <name>A0A1D2M6U6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003351">
        <property type="protein sequence ID" value="ODM88642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6U6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903539" evidence="1">
        <location>
            <begin position="28"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="373" mass="42349" checksum="4D6A9D546CDF4000" modified="2016-11-30" version="1">MVMEILNFVPISTILLISHLLFWNCEGANVMIYTHENFTGSVYALESTPICKNLPTDFKGSIKTTGCIAVYQRTNCSGRSFVVRSDKNELRELTDGVEPQDYPVQLSFRECTDLEYGLGARLDLEWILYRDSEKMELETHGGITCECIWLTWRNYHGFFANTHGNCFKVYNNADCKGNPVSEVNGHSEDIPDGGEDGGSMQLCAICLHILYRNRVKYETDRKQPQTVSGDNTQTEDKKLCDNLKNSMATVLPASKELVKGLANTFKDETGIENVRKSYEISRKKEFQVHKKVVVPKCTNYSVSSFIESLVYPQTRFNVQLKITGTNRQSNAPLTSSDTRKGLEIKDEMEMRILDTHVQADNFTVVVESTFKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8G9</accession>
    <name>A0A1D2M8G9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002753">
        <property type="protein sequence ID" value="ODM89283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8G9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="15296" checksum="2FA05C005D746FF7" modified="2016-11-30" version="1" fragment="single">QVGAGQLGDGVGREAGGAQGSHSRKGSRLVCKGNSPSGRQRRLYNGVQIPANAHQRELNNMGHHCTTTGFRWRGQPGPNNDQGGCSSQHGYWQSKTNNQGARCTKWKLPVGHGGCPKPEAANDLCHSSQQQGGALQRGEKTTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB41</accession>
    <name>A0A1D2MB41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002125">
        <property type="protein sequence ID" value="ODM90183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB41"/>
    <dbReference type="OMA" id="YHPMAPA"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="35592" checksum="AD6E37746F28BB97" modified="2016-11-30" version="1">MNSFKYLTQLFVAGGRDRKTVTKWVFLLYLLVQSGSAQFFPSSLFPSSSGNQPGSGGGGFPFQNLFPSFLGSPFQQQQQGQGQQGQPQQSNNLQQPQWPFNSLPFGQSPFYNQQQPNQQQQPGQVNPGWQQQQQPGWQQQQTSPNNPYGYQPGWNGNPQQQQPQVSPQYQNGWNGNQQQPQPSSPAISQPQPSPLSPQQPQPSPVLPQQQPQPSPVSPQQQIQPVPSPTQQQSWDDGQYKPDQYGTANPAQQPQQYVNNPQPQQPYQQQQQPYQQQPQPSQFDQGYNPQGQNLVGDLRSTLPSSDGSAPNNWVYPDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBC5</accession>
    <name>A0A1D2MBC5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fatty acid amide hydrolase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_16470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002112">
        <property type="protein sequence ID" value="ODM90211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBC5"/>
    <dbReference type="STRING" id="48709.A0A1D2MBC5"/>
    <dbReference type="OMA" id="GMQPWKY"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017064">
        <property type="term" value="F:fatty acid amide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052096">
        <property type="entry name" value="Endocannabinoid_amidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45847">
        <property type="entry name" value="FATTY ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45847:SF6">
        <property type="entry name" value="FATTY ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="4">
        <location>
            <begin position="60"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="541" mass="60076" checksum="E59EB0C4BBB36A65" modified="2016-11-30" version="1">MSVNSEFLVKIQRRQEERKVSFENLASANVLDNAAKQIVELDTVDLIQQLQSRKLTATQVLRAYIAKALELTGRVNCVTEFIPQAFEWASKLDGLNTVAGPLHGLPIAVKEDHDVEGMDTTMGFAKLLYKPAKENSTLVKILLKLGAVPFCKVNLPQSIFSYASENPIYGQTLNSINEKMGPGGSSSGSGSIVAGNGAPIAIGSDLGGSVRIPAFFHGLCSLRPTIRRLTEKGALQCTPEIDAQRGVPGFIAKNAKALSLVWRAILGNNIQNEFDPMTVPIPWNETLFSSKTQLKIGYYTSLAYFPAFLDVQKTVLNAKLALESAGHQVIPFEMPETYNYMKINFDLFTADRYSYLTKMFEGEPVSPCLTGLVESFRNPEKVWKTDEKHTKREIVSSVARRLAEEKPKSADDLWNIIMDKRAFTLDMLERMDKAGIDLILGPCFPFPAIKLEEAAAFLDAIVYTMIWNFVDFPAGVVRFGTETGANVDSYDDEGEPLLIRAKQVIRESVGMPINIQFSARPFKEELVLRALLEMENLRDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBG7</accession>
    <name>A0A1D2MBG7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ovochymase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002024">
        <property type="protein sequence ID" value="ODM90347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBG7"/>
    <dbReference type="STRING" id="48709.A0A1D2MBG7"/>
    <dbReference type="OMA" id="EGTEKMI"/>
    <dbReference type="OrthoDB" id="7863416at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000130">
        <property type="entry name" value="Chymotrypsinogen A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="145"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="71"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="353" mass="39863" checksum="63BCE6E8C6DBDA56" modified="2016-11-30" version="1">MVQFHKRETAEGSGDLVGRTLTKGLANSLIQLVTMLLVVLVLKDSFVVGYYMFPENSEDCGISVFYTHRESRGRGGNEENITFRNSSSSSRTGRYIRSSSRNSKVSKSKNSKSSYSQPRSSRANSRVMKWKSKNPADIEGPLARIVGGTVAQPYAWPWQISLQLKHPTMGFIGHWCGGVLIGAQWVITAGHCVNNRLFGLNQRGVSWFVMAGEYDRSKTEGTEKMIGVSRVFVHERFRDFDNDIALVKLSRPIQWSPTVSPVCLPNDDVQTLSFNMTGLKCVATGWGMESSKGRLSSKMQQVWVHITSQEKCDQIYQRHYHMELGIFTSVQAPKMKKLIRDMCRRFWGCVIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC41</accession>
    <name>A0A1D2MC41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mucolipin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001956">
        <property type="protein sequence ID" value="ODM90454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC41"/>
    <dbReference type="STRING" id="48709.A0A1D2MC41"/>
    <dbReference type="OMA" id="QECKDWN"/>
    <dbReference type="OrthoDB" id="263481at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072345">
        <property type="term" value="F:NAADP-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21050">
        <property type="entry name" value="ELD_TRPML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049134">
        <property type="entry name" value="MCLN_ECD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039031">
        <property type="entry name" value="Mucolipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127">
        <property type="entry name" value="MUCOLIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127:SF7">
        <property type="entry name" value="SD02261P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21381">
        <property type="entry name" value="MCLN_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Mucolipin extracytosolic" evidence="2">
        <location>
            <begin position="72"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="463" mass="53625" checksum="7CD9C121BA6FC9A0" modified="2016-11-30" version="1">MDFSENQAETATRLHFMKLKEIQLKLLLYFMNPLEKWIIRRKFPLKLAIQLLKTVFVTFQLCVFATYRSADVNYTYDNKITFSHLFLKDWDSSLEVLSFPPSTGPLAVYKQDTFFEFLDFAINAHTNVQEAAIGSYSYDTLDGVNASIKFCLDRYSNRKTLEFNKALEFNKGTNTSCINISGASPNFSSKEFFLNNNFTISFVNLLEAHLLFTLKTVRFRDLGPFKSPDCFRFDVDITFNNRGHDGQLLVKLEAPITRLQCKASKEFKEDSRLEKFGRSGVNYIVIVLCTSSFFLCCRAIYRARQLKRESIIFFKTMRNCEMTTNDQLKFVNFWYVLIIMNDILIVFGSALKESIENKQLTGDAWNFCSLLLGIGNLFMWMGILRYLGLFRSYNILILTLKHATPDVLRFLLYTILLYAGFTFSGWLILGPYNIKHSRRHRMLCDINGDAVKLLDVIRSSCGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDG1</accession>
    <name>A0A1D2MDG1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15758</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001741">
        <property type="protein sequence ID" value="ODM90921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDG1"/>
    <dbReference type="STRING" id="48709.A0A1D2MDG1"/>
    <dbReference type="OMA" id="VCWMRLE"/>
    <dbReference type="OrthoDB" id="10063861at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM90921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="293" mass="33108" checksum="E7F04AC8F38D022B" modified="2016-11-30" version="1">MKFRAKSVDLGFIRTFAQLLSALSRCSRNFVLRITPDKLIFVLSDKEAANAASSVSAWGEIPKDPYFSEYAMEGVSAEDNEIYLEISPEKIAGCLSTLRSSHSVAGLKIKLTKKFVPCLTFETEFQSINSTPTCVHDVPVVLVLRRMWSHYQDPDVPPFDISIGMPELKMVRLALDRMKNLGPRLTITANRRGRLSLSVDAYNVKCTVKFNDLRVYDINDGDVQESEEDTTQDPDLQFSVEVDMKTMIQMISSDLHKPTNFICSLCETRRLHLYFLYGDISLQYSIPSVGDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEF8</accession>
    <name>A0A1D2MEF8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras-responsive element-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15408</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001610">
        <property type="protein sequence ID" value="ODM91274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEF8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="362" mass="39099" checksum="9550744E90FC2940" modified="2016-11-30" version="1">MPVSAEVSKHGASGQDGSQYTESNNTLENGVKANVTPAPAPRAFTNVAGQPPGPSSGAALNGLNNVTRSSFDSITRILTNGLRVGSYDDRNSNISSASSSMSELFNSANNFSDSSGASRHGLNLPVGGNIGPCPSNSNSSSDSEYEPGSNDFIRAKNRKNIFKTLEGQAGIITNWSLKENDPRKVWILMGGNPYDKVIRMHGGNTGSSQPGRMLDKAFRDVTTEDRELQSESSDSASLSVIDELEPMTTSRGTSASISVVDESVDYSNCDANDSQQQSASGHGEKRNRVYSCSRCLPTTYYMNKYYWCKHVMSEHGREFRTLEKDNLYQCSTCQKVFGQKRSRADHAKIHALSQCDGGNAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEQ4</accession>
    <name>A0A1D2MEQ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitogen-activated protein kinase 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_15190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001531">
        <property type="protein sequence ID" value="ODM91497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEQ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MEQ4"/>
    <dbReference type="OrthoDB" id="8187887at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="10716" checksum="DA1E82CF9B18945C" modified="2016-11-30" version="1">MLKSEDPVGAKRELQNLPKFIHDVAKGLKWIHDSQILHRDIKPENILIVMKANGSEIAKIGDFGVSRKLSTMSTGLIHWEKERQTGWLQKPFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF22</accession>
    <name>A0A1D2MF22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-xylulose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_15092</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001495">
        <property type="protein sequence ID" value="ODM91588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF22"/>
    <dbReference type="STRING" id="48709.A0A1D2MF22"/>
    <dbReference type="OMA" id="WQSHLAV"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050038">
        <property type="term" value="F:L-xylulose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051737">
        <property type="entry name" value="L-xylulose/Carbonyl_redctase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44252:SF3">
        <property type="entry name" value="D-ERYTHRULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM91588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="225" mass="24501" checksum="5A66570731D6AF4F" modified="2016-11-30" version="1">MSLHYSFSGKRVLITGAGQGVGKRLVQRFNEGGAIILALDKNAETIELLTKEFPNVVARVVDITDWDATKKAIESFGDVDHVVNNAAVVMPQKLMEVTRETALMHFEVNTLASINIVQSATRGMIRRGTGGSIVNISSVTTKSAADSSSLYSASKAAVEMLTKSMALELGPRNIRANSISPGLIDSPMAKLNNPTVQQMVERFMQETVIKRPIEKRNCRLGFCSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFH3</accession>
    <name>A0A1D2MFH3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001439">
        <property type="protein sequence ID" value="ODM91738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFH3"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="15"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15594" checksum="1B1EB346A356BC22" modified="2016-11-30" version="1">MSVQTFDVIPDKLEYRPGEMVTGSAILKVKDGAIRSKAGSGTAAFTTPDPSPAEREYHTHVYTSSETLFNIENFLLGDGKQDLLLEEGEASYPFNFNLPSSLLSTFHRGRGRVAYKLELGLKQEAKNDLVIKRTSPLPATST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGD3</accession>
    <name>A0A1D2MGD3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001343">
        <property type="protein sequence ID" value="ODM92050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGD3"/>
    <dbReference type="STRING" id="48709.A0A1D2MGD3"/>
    <dbReference type="OrthoDB" id="7786196at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="69"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="190" mass="21764" checksum="5576F968A572A888" modified="2016-11-30" version="1">MTFTPSITKEGEYVFESISSRVSETKRVKEGIEYSGHFVINIIAPRLKGGLTCGLLWPNSSILDQETQRDFELIAKNGKRFRCHKAVLAAKSPELARMLESNCEETRGNAYRLDLCEDGVEDLIAFIYNVETTKPMRTSQTFWEMFEVAHKFQIKWLGEAIASVFLKQTYEWMDIGVAVKLFVHTLKKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGG2</accession>
    <name>A0A1D2MGG2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001334">
        <property type="protein sequence ID" value="ODM92080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGG2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="113" mass="12976" checksum="A5B5C7B77459CB65" modified="2016-11-30" version="1" fragment="single">GLITSFAKDMFEPRSQASSSSSAEPSPSKPTRPEQSVNYGLVAKRSSLEDQLRQLREELQDISKRRENQEIQLSTNENSALRQRLETVLRKTIDDQNEKERKIQEVEMELATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGM3</accession>
    <name>A0A1D2MGM3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sperm flagellar protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001339">
        <property type="protein sequence ID" value="ODM92061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGM3"/>
    <dbReference type="OrthoDB" id="62528at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052634">
        <property type="entry name" value="Sperm_flagellar-bone_growth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14919">
        <property type="entry name" value="KPL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14919:SF0">
        <property type="entry name" value="SPERM FLAGELLAR PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="795"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="866"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="964"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1064"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1208" mass="136548" checksum="F017CBBACCBD2E5F" modified="2016-11-30" version="1">MSLQYEDTAEAEDEVDFEELLEDYELPGEGDSSNPQEYNEYEGERSYEASDIPSITQIPLNNRLQSRVSSQFSILLSEPDQFQDIVDSLPDDIVDELSDFWSNMERSYAYTTFVALEGISKCHDQLLSYPDTFGHELATVLEASDDRIQYADNFKYNFNRLRYSRRIEEHIKQILRERVNELIIKMDGVIEEKYSKSKRDAYKLLSKGFLRTESERMATLFGNLLQAQTDRFVDTVRFINGHYFKLIMEDLQAPIDLAWRSLVDICLLTCGGGPWANLPLLKLHENMGEGWGQDDGGAKSISYESTCSVDTCDICGPDGQLCVETPPAAEIKLTQLVSSHERALDENEGEAEGMESEESRGELGIDFDDEEEMEGEEGGFIKRITGSEVGLRAENSSGGEQGSFGRLGRRTLVDEEDEAEDHANLVSPTKAASGKSKGTGGSKDNKKKKGRKTDPEAAPPPPPPSTRKDGRKSKKLSEKPTQKGDKSKEESGRGSKSSRRKSHTPEFIDEEDDDDEEALNEMEGEDEEEEEEGGGKISDDILRYYEEYMGEGYWEVPMMNDGRGSYGDSRRGSRLSDSSKRKGASVDFNETEEYIKDSAYWDSDSSKATTTDRSEMGKTTVSCAEKEPYDDEEYYDFDDICYLRQEFYEKPVDFKTGKMAEICTPEPENLHFSIFGKDDDFNLQDSLLNKLLKRWGQSEPDEEEEVEGEQEPMELQLSNENGSSSKGKFSDEQEKTSNNKSQVTVNDGASSDKQVPNKMHCTFTSSVPPMSETTNEKKYSYVSSYSDGKWNEKVDESAFEPNPDETLDENVANYPPAKIPVGEKRPLIESLSTLQDEIWHEFEYAFRDVQLNVEKMVGIVQEIITQGYPADVPSEESLQTEETSNEEEEEKEEETEPQDPCKKKKPKKKRCKCSHKNKPPQEATEGGGAAEGKPHLKKCGEDSGGSKPGSKPESKSPPDGTSGDNEEGGGTGEEENSPEEEEADEAEVDAEEIVTTVTTHLEFPEEQESEGRGSGNFDMTKDPLYYKGEYLGEGFWEVEHSDHEETKEEDENDEEKEENDENDEQLERVNFNAVIRTKLQNWETTLQLEVERLRRHLMVIGIKAHEELNLFRELPYKVWERSKKQAANIYIEDLSRDVEVGDIFRCAIDSTSQLSGNFYIDTRDVKLLLNGTEPPIPLDYPESLRILPASVMEDGESSFEEIISAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHD2</accession>
    <name>A0A1D2MHD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-chimaerin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001242">
        <property type="protein sequence ID" value="ODM92399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHD2"/>
    <dbReference type="STRING" id="48709.A0A1D2MHD2"/>
    <dbReference type="OMA" id="SATHLIC"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051854">
        <property type="entry name" value="Rho-type_GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075">
        <property type="entry name" value="CHIMERIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075:SF2">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="37"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="226" mass="25393" checksum="23DE3957FCAEFD39" modified="2016-11-30" version="1">MRFFLHADCGLSIHESCVDDVKSECKPDLTTTPPFSTDLTTLVKASYAVANGSCGLPYVLEKCINEVETRGLSTEGIYRVSGAVDEIESLKTLFEKDRINTDLSICSDIHSITGLIKLFLRQLPEPLITEEVFEEFFREEAGEMNLETVQNLILCLPPAHRLTLKHLLEHLQNVTMEKASNKMNAFNLSSVLMPSIVGPTNMSFNHLESCTKLLYVMITKFKNLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MID4</accession>
    <name>A0A1D2MID4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001176">
        <property type="protein sequence ID" value="ODM92681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MID4"/>
    <dbReference type="STRING" id="48709.A0A1D2MID4"/>
    <dbReference type="OMA" id="QGLNCLI"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="251" mass="27216" checksum="5E949099BA274CC1" modified="2016-11-30" version="1">MARPKNIVVTGANRGIGLELVKQLITKFNPDNIFATYRDPENSKDLLQLASQNGNLHAVILDVRDTDKYADFVTNVESTTQGAGINLLINNSGFFNKENNTSLSQLDKADLMYHFEINTLAPMMLTKAFLPLLEKGSKANGSQPLGIGRAAVLQVSTNMGSIGDNTSGGAYGYRISKTALNQASKNMSLDLLPKGILVIPLHPGWVKTDMGGSNALITTEECVTGILSVLENLNEDTNGHFMRFDGKEALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIF1</accession>
    <name>A0A1D2MIF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001150">
        <property type="protein sequence ID" value="ODM92787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIF1"/>
    <dbReference type="STRING" id="48709.A0A1D2MIF1"/>
    <dbReference type="OrthoDB" id="70250at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007720">
        <property type="entry name" value="PigQ/GPI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329:SF3">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05024">
        <property type="entry name" value="Gpi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="481" mass="54422" checksum="92F7B005A715E935" modified="2016-11-30" version="1">MYFNTDLGFSERLPVFHIFFPTTFAQRVSNFLEERGIDSCFVVGQTELRVLKPVRRPRSPPPVGKSPLSFINEVGIRTRSKSRSKNKRRKSGGDGDDSSSRTTTTSSPPPSPFKTEESYQQPQPSSSSKEEEECSTFAVNILGITDNLHNFQGGDSVNSLQIIGRCSKPTSKSSSTSRANSTLFLDLNLEKNGDNLSSFSVEIDYPKIFWKESPPPDPLTIITILHTRLPQIPQDHQDLNLCNTAPSFITSSPLHSFISKKSSGLEQITHKVSILVLGLLGNYPLFPLLNFIFLLLLDSLFGYLITSYLLQFPNLLGFLHEAVDQMLFYLNHLLKWLHGAPAGLKLNHNLNSLYWRFFSYHIHLWASYIGILEPVFAVILNTIQYLGGLGITIQISLLKDLINLATFHVYCLYIYATRLYSIQTTAIVFFGRKYSHLRNRFDSVQLNTSELFISSFGFVILIFLFPTTMVYYAGFVCVIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MII2</accession>
    <name>A0A1D2MII2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001166">
        <property type="protein sequence ID" value="ODM92722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MII2"/>
    <dbReference type="OMA" id="EASTEYE"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1314"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1512"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1605"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1720"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="747"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="875"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="968"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1127"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1179"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1254"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1278"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1314"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1389"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1465"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1527"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1641"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1663"/>
            <end position="1675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1796" mass="195867" checksum="498E6E8AEC74941D" modified="2016-11-30" version="1">MKVVAQSIPKPVVSSANIIKNNDFLQSGLKANSSGSSPPKKEPQPSTSAAALKAETKKSATSVQPSNPSSSPSTRRKRVIITAPLSPPSTRSSSVLHKKTEHVVGKASPSTPSKKIVSSPTKKKEISATTPVVATLSESQSSASSSPSKKKGKKSKKKRRSPSPNIRVESVVSMAPAKKSAAKKPVEVVAKPEEKKKEKVRKEPTLVLNENRRPTLALVTIPSPESVEKEEEEEETVGDLLQNEVEEEEKVECILPHDIDEETQKEEEQLSQFPAASNDDNGGVDVDPLGEEGVQELPIVLWTYSIPGDVKPEEKLQEFQLEPDNDVKLVSSPPPAAEVVSAVPEAVATTAAAEEERRLLESLSPCPISDDEFPEFDDDEEEPMQTEETTEKEVETPSSQVEPTISSPPISPSTTVILTEPETVEKADEDVPSPVVSDDNQLEESSKNETELEVEGAEKEALVVVTEEQSSIPAASPSPTPSELGISFDEPPPADAVESSKVEIELDESASSPTIPTILEEEKEAPTSSPEAIQKLVEPEEGELVEDEPEAPIIIVAAAPPPPPSPPKEEEKPVVTERVVDHSTSLSPCPISDDEFCFEEDEDEREPEELGQTQTEPKSVEDLKLSEEKQIIVVDEKDQEQPELTPESSPKTVVEDCSASSPAAVDEMRGEKSVPCSPSHEEKDDDALIETDSQLEGAVRETVDELEKQVEEECDKEIESICTTEPDQFEAEKELQVVATGSPSETLELEEESEVEEEETKAEPDDTIASLAVDELPKSPVEPETMTTEQAELEQEEGELVDEEEDKELDFEDKMELAKQVDALVETLVEEEDEEEETVQETAIPEEKSISEKSSPAQSQPEPYNSDSLSPCPISDDELPDDDDDEDYLEQQKEQLEPEKSPETKVALVFTEKEEEPESIPAEPQTSAAELPSPTTQDRAQQCSPPPLVFVNDVKKEEVEEEEETVDNSDSSLTTTSVDSIDEKEVAAETILSIPKEEEPEVETKLEVDVGEGCSSAECAIPAFIDGEIEAAELPTEKEALELPIEREAPELLAEKEALELPIEKEAEIVPEDEEEIEKEEVAVAPLDIQVDSIEKEQEEEVEQEKEEEDQEETGVNRASPLPIAPDVEELEEQPEEKLVEDDSEHEEGELIDDEEEEEETTSEMELVKHLPVEEPTPSAQPVPPTPPSILEEKEEEQVEKLTESPPVADSQVDFEEKPESPEETAVAVASPHLPEEKEEEEVAHKAPTPPGQLEKESSSPEHLEEEEEDERLSVVMESDEEDKENDDGGISSGKGTCDLYDDILWPKPKLVSVDSLHHSSPSSTTLPKSPEETVTSDGEKIEEDEDDLEEEEIEEDDDDDRLCIDEEYEPPSTSDSLKASEPEPPTPTKEEEKPKEEVAIEQLALPQEEEEEKEVSSPSPIIEKPETLPPDISDFVLSVMDKTNEEDLSSISSESLASPETEPLGNSIQNAISTLDDDLDREDKALQEKEDEEEEEYHIKKVAGPFLSELNCDGTSPPVATNTNGSLSSSSCSSESPLKAVSNLISKIPMTTIPPSPSPPIKASAVVAPLPKEPPLTKGALKCLSPPLQQESPVELHVAPVKTPPLVPSIQSSEKLDESPPPVAPASKCVSPPVILHDTQVPERKSPPMVPKEELPVAVAPSPTPPPPPPPPMPTLKVNGMLTAMVAPTPAISQPPRVEKRAREEYQEYPTRVQFILPNQSVSTALPSSGGGEQLPPPATNSNSTSNLSYEPSLLYFVRPDGSPAAEGDYQLVYAAAAATAFTRKELGTSRPRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJD7</accession>
    <name>A0A1D2MJD7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GATA-binding factor C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001062">
        <property type="protein sequence ID" value="ODM93147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJD7"/>
    <dbReference type="STRING" id="48709.A0A1D2MJD7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="299" mass="30693" checksum="A9D6744862F65020" modified="2016-11-30" version="1">MRYMETHFLGSPSSTSSAGSLQQQYHNQHNHNNQISSSPPSSVANNSGLNNNNTTDTSSPSSNCLGVEDMASADVFFSEVTNTSRVARYYSGSMHSYSQMQRMAQGGGSMSGSPTGSHPGTNPHQVCRPHFHHPPPLHHPWLPTIITCLNKRQISQLAAPPQCGTSGNSGSNSSSSTGHHSHHPHNSIFPFPPTPPKDTTPETITPTSAHQDMYGGGGGGGGVDLDVKPSSLLSIPGGGGGAGGGSGGASGGLKPSREGSTTSSSSSSGGGGGGAGGAMSHFGIWWRISSSQQFHQPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKV9</accession>
    <name>A0A1D2MKV9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 15">Receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2 15">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_13089</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2 15"/>
    <dbReference type="EMBL" id="LJIJ01000949">
        <property type="protein sequence ID" value="ODM93593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MKV9"/>
    <dbReference type="OMA" id="GYYYEWV"/>
    <dbReference type="OrthoDB" id="6219513at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009925">
        <property type="term" value="C:basal plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038127">
        <property type="term" value="P:ERBB signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022008">
        <property type="term" value="P:neurogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008284">
        <property type="term" value="P:positive regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00064">
        <property type="entry name" value="FU"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd05057">
        <property type="entry name" value="PTKc_EGFR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000027">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.220.10:FF:000001">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.220.10:FF:000002">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.220.10:FF:000024">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000422">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.220.10">
        <property type="entry name" value="Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006211">
        <property type="entry name" value="Furin-like_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032778">
        <property type="entry name" value="GF_recep_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000494">
        <property type="entry name" value="Rcpt_L-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016245">
        <property type="entry name" value="Tyr_kinase_EGF/ERB/XmrK_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF566">
        <property type="entry name" value="EPIDERMAL GROWTH FACTOR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00757">
        <property type="entry name" value="Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14843">
        <property type="entry name" value="GF_recep_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01030">
        <property type="entry name" value="Recep_L_domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000619">
        <property type="entry name" value="TyrPK_EGF-R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 15 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 15 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12 15 22" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 15" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="806"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="937"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="875"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1186"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1356"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1188"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1379"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1414"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="1000"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="881"/>
            <end position="889"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17 18">
        <location>
            <position position="908"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000619-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODM93593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1449" mass="162444" checksum="0E707BDC7F34C9DF" modified="2016-11-30" version="1">MASIRSIQGDGTAEQRYIKGKEDGDVVLISSSVCIGTNGRMSVPSNRSHHYRNLKDRYTNCTYVEGNLELTWIQDRDMDLSFLQHIREVTGYVLISHVDVKRIVLPSLQVIRGRTLFRLNVHDDEFALMVTLSRMDNLELPALRDVLNGNVGIFNNYNLCHVKTINWDEIISGINSRYVYVYNYTQPERECPPCDPSCEAGCWGEGPHNCQKFSKINCSPQCHEGRCYGPEPRQCCHLSCAGGCTGPKKSDCLACKKFYDDGECKDECPSLVIYNPNTYLSERNPAGKYAYGATCVKTCPDHLLRDAGAGACVRQCPRDKEARDGECVPCNGPCRKKCQGPSNAIIHSGNIESFRNCTIIDGNIAILETSFNGFQEVHQNFTFGERYAPMEPSKLEVFSTLKEVTGYINIQATHPDFHNLSYFRNLDTIGGRDKTDYFASLYIVKSSIQALHLRSLKKIRSGAVVILENEHLCYAHEINWSKIKSEKADVQIYNNRGKEECEKTGDVCSSQCSKDGCWGVEPRDCLSCAKYKLDDQCVPSCNSTIGTYEDTPGLCKHCHEQCERTCHGAGPGNCTRCKNVKDGPFCVQSCPEHKYNVGGDCFKCHDNCVEGCTGPANTIGYSGCNSCHQAIVHETDHVFTIERCLGKEDVCPTGYYYESVSPKEQGPLKPLAGKSVCKKCHSRCNKCTAFGFHVHVCQECTHYRKGEQCEDECPAEFYADEERRECLPCAEECRSCVGPTANNCDNCRNFRIYPDGDAGNEVNSSFICTMHCPPEYPHRIVENENEPFCARNPPISETIDQNPKSAVILTSVLCVFLFAVFAVIVGLYCFKAKTKANEIKMTIAMTGGYDDNEPLRPTNVKPNLNKFRTVKEEELRRGGMLGYGAFGTVYKGVWIPEGQNVKIPVAIKVLKEGTGANASKEFLDEAYIMASVEHPHLLKLLAVCLSSQLMLVTQLMPLGCLRDYVHNNKEKIGSKAMLNWCTQIARGMEYLESRRLVHRDLAARNVLIHTPNTVKITDFGLAKLLDLDEDEYKAEGGKLPIKWLAIECIKDRVFTHKSDVWAFGVTVWELLTYGGKPYENVPLRDVPDLLMKGERLEQPSICTLELYMIVIKTWMVDPEARPSFKELVDEFTKMSRDPGRYLYIKGDPLKKLPSYTPQDEQELIRNLSSAMDGPETIMDAEEYLQPRSNGTTTTTSSSASTNGTLKRNAGVAGMGSLGGICSQENNWPESPQNFHNRYRERHRYGSNDSSKSREANVGNLKLDLPVDEDDYLMPSPQTNQNASTYLDLVSDSGNHETGDNNELRRYAMRNNHHHYPTLVDNPEYQLMAREYTNVPLAYAPIGLPLAPNSGSSIVSTNSAPPHLHNGQILGNFAHPVAPSSSNSSSSNKQQQQQPYYLQAPNSFNRPSSIVRHSSRSEEESDHEYYNELDKLKREKQPLQQSVRKNETTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLD1</accession>
    <name>A0A1D2MLD1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12813</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000899">
        <property type="protein sequence ID" value="ODM93869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLD1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="252" mass="27870" checksum="7D49CB0349AA6C3D" modified="2016-11-30" version="1">MKTNCKCVIALLSQSKGCNFKVTTKNPSEEDALENEVESQQSRVMIEQALQAMHLYETKGFYVKYSGLPCCPSLKISPSIMGSGLFSVSPTSWAIKASSNNYGCFCCFMPASWSWQTITLNLGEQEVLNFIYRPQIWSCFGTKDRIVDIYVPQRNERIGLLKYKGNLDDGTIITDAISRSLFLAAKIADHPTPGFKITDNIGIPVAVAQASRGLRYRGITTWTDFELQYAPLAANMPASSKAILAVGFLMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLY7</accession>
    <name>A0A1D2MLY7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000883">
        <property type="protein sequence ID" value="ODM93958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLY7"/>
    <dbReference type="OrthoDB" id="10566189at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="242" mass="28599" checksum="B3DC82DF8B050D3B" modified="2016-11-30" version="1">MNEELKIINEENHIMRKEIEKMENKLNSLQASTQNLTEENTVLKREITGMIDRKDALTQSLERERVKSDIFEKENKTMKETVMTIDAQLKESSEQRTHWQERARCSESQVWELQLHLESREDSIKELTKECDALRDEKMQLIDLKSKLKSNLDKTAVTLKVLGEKNEELKETFEAVKAERDAKAETLHALEEILEKTKNEFTEVEKELLSFKLQNVRRRREWGNALYFIVSPMDAMKKRLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM43</accession>
    <name>A0A1D2MM43_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhythmically expressed gene 2 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000865">
        <property type="protein sequence ID" value="ODM94073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM43"/>
    <dbReference type="STRING" id="48709.A0A1D2MM43"/>
    <dbReference type="OMA" id="GARSANW"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051828">
        <property type="entry name" value="HAD-like_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011949">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02252">
        <property type="entry name" value="DREG-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191:SF2">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="33566" checksum="1B487937F12ED0D2" modified="2016-11-30" version="1" fragment="single">MISLRVHRVVQRVAAHSRNNFMCTSSSHLCSQSNSQSSSYSSRLDLENVKLITFDVTGTLLAFRKPPFDIYMDFGKKYGVTCERDLIKASFKAQWKQLNAEQPHYGKCWEAWWTEIVMRTFKEANAQGANDATLRKVASSLIEHFKTDECWMLTEGAKELMNALSNVKNNGVAIGIISNFDPRLHQLLKTFKMDSQFNPVILSHEHQVSKPSKGIFNLALASYPKTMSGMSIKPSEALHVGDNYELDYVGAVKAGWKSCLITPNLNINEIPETRRISQLPKIFEDLRAFHNFLADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM48</accession>
    <name>A0A1D2MM48_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Neurexin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_12741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000887">
        <property type="protein sequence ID" value="ODM93931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM48"/>
    <dbReference type="STRING" id="48709.A0A1D2MM48"/>
    <dbReference type="OMA" id="CVENPCE"/>
    <dbReference type="OrthoDB" id="6275838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050372">
        <property type="entry name" value="Neurexin-related_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036:SF49">
        <property type="entry name" value="AXOTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036">
        <property type="entry name" value="PIKACHURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012972439" evidence="3">
        <location>
            <begin position="16"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="4">
        <location>
            <begin position="15"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="204"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM93931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="318" mass="35416" checksum="9FD6452E93DF192B" modified="2016-11-30" version="1">MRIPILLSLLPLAWSFVLEGSDTSYARFSRWNVNTTLSFEFNTNQPDGLIVYTDDGGKSDFFELKLVEGILRLRFNLLNQGTQLINIGQHLNDGLWHRVELSVSVWNVLVTVDGFVSQGRNMLSEKLQIRFDNTGVFIGGLPGYFNSRLGELTLPSVVFEPRFRGAVRNLVFGAQSHDHVQNTKIVVKPQEIVESKGLISGSATSEACERHDPCLHGGFCISTDSGPVCDCKHIDFEGVNCELEKSPTTATFHGSEYIGYDFRESGGQQPIISQLDEISLYFKTSTRTSCCSTRCCSTLGRGGLHRAKYKERPADAQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM71</accession>
    <name>A0A1D2MM71_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannan endo-1,6-alpha-mannosidase DFG5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000867">
        <property type="protein sequence ID" value="ODM94048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM71"/>
    <dbReference type="STRING" id="48709.A0A1D2MM71"/>
    <dbReference type="OrthoDB" id="8249190at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904246" evidence="1">
        <location>
            <begin position="19"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="465" mass="51883" checksum="CC0C40A072415A12" modified="2016-11-30" version="1">MRHLYLLALLLLASVASAQVCNIFCDGRGSGESPNSREAVSAEIFGRRIRLYISDSDNMGFAEMSNGDPGDEVWIDRSFNAGVGWDGKLGTSFIPSGSREVRTLMYNVDNPSGQQIGALRACGKPGNMEDIACTSWARSTVNAERQVDAAATALMQFWNGALWSTTGWWNGANCLNALLDYFTLTGAQNYRYMIDTTFERNKNEHFGDFTNDYIDDTLWWGLAWLRAYELTGNQKYLETAKHTSDYSYDGYRDDVCGGGVWWRIQKDYKNAITNELFIKLAASLHNKIPGDTKYLSQAVEVWNWLKNSGMINNENLINDGLTDDCRNNGDVTWSYNQGVILGGLTELFKATRDQNYLTEARKIADAVMNSGALNPNGILREYGCGDGDCGVDGASFKGAFVRNLGELNRELDGRPYSEWLRNQAASNWNNNRNSLNQFGLRWEGPVDKIDASRQHSALEAFIAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMF9</accession>
    <name>A0A1D2MMF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannan endo-1,6-alpha-mannosidase DCW1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000867">
        <property type="protein sequence ID" value="ODM94051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMF9"/>
    <dbReference type="STRING" id="48709.A0A1D2MMF9"/>
    <dbReference type="OrthoDB" id="8249190at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF3">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904261" evidence="1">
        <location>
            <begin position="22"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="467" mass="52411" checksum="A336D32BE5E3E74E" modified="2016-11-30" version="1">MDSRHFLVLFLVGVSFETGSAQICNIHCDALDPAQAINTREAASVQIFGRTIRLYISDSDNMGWADISNGSPTDEVWIDRSFNAGFEWEGPLGHTTIPTGMQNWRTLMYNVDNPSGQQIGALRACGKAGDRDDIACTSWARSTVNAETRVDAAATAMMQFYNGKLFSTAGWWNGANCLTALLDYFKITGSQTYRNVIDEIFERNKDEAFGNFLNDYIDDVLWWGLAWVNAYDLTGNTKYLDMAKINSDYGWSFKDNHCGGGLWWSTDKDYKNAIPNELFIKLAAALHNRIPGDTMYLSQSVEVWNWFKNSGMINQENLINDGLTDDCQNNERIAWSYNQGVILGGLLELHKATNDQSYIDEAKKIVEAVFRSDQLTPNGILTDYGCEPGDCGGDVPTFKGVFVRNLAELNRFLPDKPYTSWLQTQANSIWENNRNTLNQFGLRWAGTFDKVDAARHQSAFEAFVAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMN8</accession>
    <name>A0A1D2MMN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000838">
        <property type="protein sequence ID" value="ODM94233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMN8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904285" evidence="1">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="75" mass="7764" checksum="C0125E8E8FCA8237" modified="2016-11-30" version="1">MNSSSKIILFGLLIAVAFLVENSSAQSGPSVPASRNRSNAQCTTCSGACAGYFCCDGVHKICGVSGNQCLCFRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNF0</accession>
    <name>A0A1D2MNF0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000787">
        <property type="protein sequence ID" value="ODM94557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNF0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="425" mass="48756" checksum="2C268CC7B09D66C2" modified="2016-11-30" version="1">MKNKPGPKLSGRSSTVSLRSTPSAKKRRKERRKAKQQKSEDVLEQVNKPPPYKFVDTTLDLGEESETLEIYPTKSAPTVADIEDDLAREHEKEKLKFFNVPIKIYDPDKDAERDEGMKRQETTELNRYGSRVIMNTEGHVIGMEVRTDLIKDTKRKNITTEICQCIEREYGVSEGLKSNRKVRRRFMARVLFIEAAFRTPSILFYIVQSNFEGLHDFLYQQNLLTFFIICIIQGTRIASVMFSDIGRYEPCLTIITVLTVLGHSLLLTLLTAIMQSVQMYFTQYEEFEDPTSLLTVNIKKKTTEFSYPYCFCMGTAFQLILNCLLGSILMLSKKRMAEFGNSFLAVLAVATILWAGTCLSVVIFANHLVGIRVVTSWDFVQVVAASVCVCKWCMWRFFMLQELLRGKVTEVKETYHHVVALNFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP49</accession>
    <name>A0A1D2MP49_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_11892</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000750">
        <property type="protein sequence ID" value="ODM94793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP49"/>
    <dbReference type="STRING" id="48709.A0A1D2MP49"/>
    <dbReference type="OMA" id="YGAYWQD"/>
    <dbReference type="OrthoDB" id="7775173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM94793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="506" mass="58902" checksum="881CD7E5EEF0D825" modified="2016-11-30" version="1">MDIIVCYILLGLLSLLLLIYLNENLRTKRNLPPGPFRLPVIGNLIQVALADSKEPYKAFKKLGQQYGDIMSIQLGSLYSVVLNSYEDMEEYLPTADYSDRLFTAWFAERTFDKRLGIIFAKYQEPWQVLRRFCLRSLRDFGFGKRSKMHTVIESELHDIVKELQMSVKENDGIHTFDCYFTLSVLNVLWAMLAGTRYEHSDPKLLRLIKLTRDMMSSCNFGNNILLAYPEWKDWFPDWTGLTVQRKCYRETNAFFQEFIDQRRKLGAYKTNPENMVDEFIREIETNGEDTVYSDQQLVIIMNDLFVAGSETTSHTISWCILYLLLNQDIQNKLQEEIDLIVPKGTFPTVEQESQLHYLKAVLAETHRIASVVPLMVPRAAEKDTTCRKYFIPKGTYVIANIHGMHHNKDYWKDPDTFCPERFLDADGKYKPDARLKPFGFGKRLCLGARHHIDPFTISPSSKLHFTQSQPTSTFRGSRSWSHKRTSNISSFDKVSMNRNLKHQHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ52</accession>
    <name>A0A1D2MQ52_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000720">
        <property type="protein sequence ID" value="ODM95018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ52"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904375" evidence="2">
        <location>
            <begin position="21"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="121" mass="13227" checksum="F42F7105077A1D9A" modified="2016-11-30" version="1">MRNLGAFLLATLALVLMAEARPDPEPRADPEPLPQGSIGAQGKKKAEFQIGAGNMFGNPNAGVEPPAYDDGDDDYSSSSSEEVKKKKKKGKKDKKKKSKKDKKKKKDSDEDDDDDDDDDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ60</accession>
    <name>A0A1D2MQ60_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_11510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000702">
        <property type="protein sequence ID" value="ODM95173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ60"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ60"/>
    <dbReference type="OrthoDB" id="8113227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="191"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="356" mass="40035" checksum="0F88BF9B17C974EC" modified="2016-11-30" version="1">MESLEQQVKELQIGLGAVVQALTFIQTFLESDYGLKFQFHAYRSSPVYSQHSSLLESLKTKYGQENESFHSNKASSVTFSGNEGIQYHAQEESSLESNMTCTISSVSSSSNPSMTVQTFVPLRESGESRSVQSQSHHHTTPPLITGDLQTICDKSTVIVQHEGIPMFNVTELEMKQELATEMYHDEDDELDAFASDGDDENEGEGDEDGESVEDHTTISNEDTHVDEDEASTLTVEQPCGSAETSGESRKSVATSQVKSKSKRRKVSDKHSEFKCPHCRRRCADQAALELHMTHHKQQFQCSQCGIWLADKSVLNRHMRMHTGSRPFSCEFCSDSFARQDIAKKHIQRKHKDMLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQY2</accession>
    <name>A0A1D2MQY2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11397</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="LJIJ01000689">
        <property type="protein sequence ID" value="ODM95281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQY2"/>
    <dbReference type="STRING" id="48709.A0A1D2MQY2"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032587">
        <property type="term" value="C:ruffle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046488">
        <property type="term" value="P:phosphatidylinositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000039">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF159">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="8">
        <location>
            <begin position="468"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="587"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM95281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="760" mass="86672" checksum="D7036C711F580E76" modified="2016-11-30" version="1">MGLEKKEAKQRKLSVCGQDVMKVAKAVINDSKVFNTVFNGHIRDAKLFQPDFHEFLMETQKEDETNILHFKHLFTRNEENGIAYMTPSEAENFLFSDENELCKPECSAVYQDMTRPLSHYWIASSHNTYLTGDQFKSDSSPDAYARCLQQGCRCLEIDCWNNPEPDGSPLIYHGYTMTSKIYLKDVLQTIKKYAFVKSAYPIILSIENHCSIQQQKVMAQMLQETFQDSLVSHPCKDNETELPSPEDLKYKILIKCKAINNEDLNGTISNGFSGPDSDLQFSCIQTRKRGILHCRNPRNGCWEPYKCILTDEKLIFIKLEGDKIRSLSSHNISLNTYPSTPSNDWRRGARKPVKVHRRSSFTEEWAPVNFADFNLISSGFSGNLPTPDRYCLELEYSACCAEIERNNGHEDLPHLIRITNRQTLIDTATAKIEEANEWKQGINEVARSRPRSCETASNRRRDKISDDLARLAVYARTTKFRLISSDKAKARTFNEMHSLPEKVALKTMTSNPSQFIMYHQVQFGRVYPTGTRLYSSNYDPTPLWNLGCQMVALNYQTPDKPLQLNHGKFQDNGGCGYVLKPSYLLLKDFNPNAMMDYIKFGNPKMNFTITVIAARHLESTRKAAAANPFVDIELFGAKCDNDSFALVKHRTSCANNLFNEVVLFINNTLGVLLLISGKNRLNPFWNKSFSFRVAAPELALIRFSVQNERLVGDPIFMGQATYPILSLRPGVRSINLRNGFGEDLMAVLLVKCERRTCDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-03-27" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRD0</accession>
    <name>A0A1D2MRD0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000689">
        <property type="protein sequence ID" value="ODM95285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRD0"/>
    <dbReference type="OMA" id="CTLSCPR"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904423" evidence="1">
        <location>
            <begin position="18"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="172" mass="18078" checksum="C27C8BE4705FACAE" modified="2016-11-30" version="1">MQSIVVAVLCTLAVANAGFTPVIQTVHAAPVVHTVQASQLSMPCTLSCPRATPVVHAVHTAPLYKTAVIPTAYATSYKYRAAPAKIVVSHPVVVAAPRPLYKAIVPTAYASSYSYRAPAAKIITPVVQKTLITTPVLHKTVVAAPIVHHAPVLHSVVHASPIVHHAPTVLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS02</accession>
    <name>A0A1D2MS02_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Glycogen [starch] synthase</fullName>
            <ecNumber evidence="3 10">2.4.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11096</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18549"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:18550"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.11" evidence="3 10"/>
    <dbReference type="EMBL" id="LJIJ01000649">
        <property type="protein sequence ID" value="ODM95584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS02"/>
    <dbReference type="STRING" id="48709.A0A1D2MS02"/>
    <dbReference type="OMA" id="RDVRNHI"/>
    <dbReference type="OrthoDB" id="6335297at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000014">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000028">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008631">
        <property type="entry name" value="Glycogen_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176:SF3">
        <property type="entry name" value="GLYCOGEN [STARCH] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176">
        <property type="entry name" value="GLYCOGEN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05693">
        <property type="entry name" value="Glycogen_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="643"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM95584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="692" mass="78920" checksum="6F0124D35E17D86A" modified="2016-11-30" version="1">MASRELKMSRRFYRVESQQDLMAYMDRGDSALRENRWTLEIAWEAANKVGGIYTVIRSKAYVSTEEMGDQYCLFGPYKEHCARQEVELGDLSQDNPLQIAANRLREAGFDVKVGRWLVDGNPLIVLFELGSGSTKLNEWKQELWEKTGVGIPQQDIECNDSVIFGFMTAMFIAEFRKAAEETAGGVQPKIVAHFHEWLAGIGLIMLRLWNTDVATVFTTHATLLGRFLCAGALDFYNNLDKFNIDEEAGRRQIYHRYCMERAASQMSHVFTTVSEITGLEAEHLIKRKPDFITPNGLNVKKFAAIHEFQNLHAIAKEKINEFVRGHFYGHFDFNLDKTLYFFIAGRYEFGNKGADIFIEALARLNHFLKSSGSDKTVVAFLIFPCKTNNFNVESLRGQALTKSLRNTINDVQQDIGKRMYEICLSGRLPTNEEILLKDDMVKIKRCLFSLQRSTLPPITTHNVVEDWKDPVLNGLRRCNLFNSVNDRVKVIFHPEFLSSTNPLFGLDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSITTNLSGFGCFMAEHIADPQSYGIYIVDRRNIGLEESVTQLARNMFDFCMLNRRQRIIQRNRTERLSDLLDWRNLGVYYRQSRMKAMKVVYSGIEDYDGQGAGRMSYPRPISEPPSPQSSRAASPDPSDNDSVDSENELQELTGAKGHNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSH1</accession>
    <name>A0A1D2MSH1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isocitrate dehydrogenase [NAD] subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_10651</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000591">
        <property type="protein sequence ID" value="ODM96040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSH1"/>
    <dbReference type="STRING" id="48709.A0A1D2MSH1"/>
    <dbReference type="OMA" id="VRPCRYY"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000003">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="12">
        <location>
            <begin position="26"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00065927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM96040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="357" mass="38852" checksum="9AD21FAD51220943" modified="2016-11-30" version="1">MASGVFRRLLPINRNYCNVRFASTRTVTLIPGDGIGPEISAAVQKIFSAAQVPINWEPVDVTSVKGPDGKFGIPQAAIDSVNKNEIGLKGPLMTPIGKGHRSLNLALRKEFNLYANVRPCKSLDGYETLYKDVDVVTIRENTEGEYSGIEHEIVPGVVQSIKLITEDASRRVADFAFSYAKANGRSKVTVVHKANIMRMSDGLFLRCCREASKKFPEIKMEERYLDTVCLTMVQDPSQYDVLVMPNLYGDILSDLCAGLVGGLGLTPSGNIGLNGAIFESVHGTAPDIAGQDKANPTALLLSAVMMLRYMELGTYANKIEKACFEVIREGNKLTGDLGGKGKCSEFTDEICKKVESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSI4</accession>
    <name>A0A1D2MSI4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP synthase subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000596">
        <property type="protein sequence ID" value="ODM95993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSI4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="311" mass="35557" checksum="4B5321BDFDC3F53F" modified="2016-11-30" version="1">METQTLLTLAQLLKQPLLTTEDSIEKTSDGDKDSDNVKSSTIFGLRSEDRYRVLKLIEELVDAQETADKLRQKLDDEKTDFREKRSALMKKLDILSEKHEKSLSNIQRLKEKHSHSLQMLEDKISTVSQKFEASLVDIKELRKVNAELKEENTVLRKLNSKYLERLSAMQDETSRLTYLVDENRNIEKAVKRQLKNLTSGRSINWENKRDRLLLGSNISCHSNSVNDSYCEESLKGAGDFINHLRQSSSYGFNTIKAPISIDVNKLPESSVVIPTNSIPVSTPNTEKTLDSTLANSELTDMTILENLFFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MST0</accession>
    <name>A0A1D2MST0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Aminopeptidase</fullName>
            <ecNumber evidence="18">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_10501</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="16 18">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16 18">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="18"/>
    <dbReference type="EMBL" id="LJIJ01000568">
        <property type="protein sequence ID" value="ODM96179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MST0"/>
    <dbReference type="STRING" id="48709.A0A1D2MST0"/>
    <dbReference type="OMA" id="VEANIRW"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000013">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000012">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF18">
        <property type="entry name" value="FI02158P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 18 23" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 18" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 18" id="KW-0645">Protease</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="19" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9 16 18" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904487" description="Aminopeptidase" evidence="19">
        <location>
            <begin position="23"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="22">
        <location>
            <begin position="61"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="20">
        <location>
            <begin position="299"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="21">
        <location>
            <begin position="608"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="17">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODM96179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="948" mass="106670" checksum="E32940850358D4C4" modified="2016-11-30" version="1">MHIKIFCSLVLLCTTSIKVSTAVTPLQLTRDGAAPTSPQEDFLKVIRVPSPKFRLPNDVLPFHYDLRLRPRLTATDPNDGPQWTAPGQVTILVTCVQTTRNISLHSTVREINESSVTITNIQTGLTIAVETHSYVPEKDFYVITLTSAMQIGQRYSIFIDYVADVFTNRLDGLYRSHYDDPASGETKWAATTQFQAFGARAAYPCFDEPGLKATFNITLGREHNFSAVANTPIIDTLPIDGLDNWFWDIFKQTVPMPTYLVALVISDYAFAEASSDLYNKPTRTYAPKHLIDQGHGDFAAMVAAKDLAFFEEFFDYEYALDKMDSAAMWDFAAGAMENWGINIYREVLILYAPNQNNERERRQVSQTLAHELAHQWFGNLVTCAWWTGAWLNEGFASWIQYLGLNHTDPEFESLKTILNDAMQNAMRSDVLANSHPTLLPDKGNPYDTMSYSGNLVYSKGAALIRMMENFLTIGTLQAGLRTYLKRNAFGAVEQDDLFEALTEHALADNRLPEGVTMKTIMDTWTLQKAYPLLKVRHSTSDNIVTITQEEDQGTFGKRPIQSGTNQENPLWFVPMAVSTQSNPQPDNTIPQYWLSTSEMTIPHNSSEWLIVNSGATGYYRVEYDAVLTQRLHDQILRDFTVLNYGTRSQLLDDYFTRAFTGNQQISAALGFTRHLEQELEYVVWAPFFYHMAKPYRLFSGTEVFDSMKEYILPKISDVMDSLQTTRNISFGIDNILYAQLFDWSCGMGNPSCVNQSLAFFETWKSNPDVNPIDPMLRPIVYCTAIANRIDNFQFALERFAASTGTQQTQLLTALGCTTNNASVALLLGAADGSTSQISRQFALAALQSVAANHLHRGTLESFIRNSIEDVVEYVGNAAIIANTLRSLSSYYSSARELLFVNDLAAQYSDLLGAPGVTEIVEAAITAIEDNILWTARFREQFHIWFQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSV1</accession>
    <name>A0A1D2MSV1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000583">
        <property type="protein sequence ID" value="ODM96086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSV1"/>
    <dbReference type="OMA" id="HKQEGMF"/>
    <dbReference type="OrthoDB" id="330671at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009218">
        <property type="entry name" value="HD_phosphohydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21174">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21174:SF0">
        <property type="entry name" value="HD PHOSPHOHYDROLASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035170">
        <property type="entry name" value="HD_phosphohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="16818" checksum="C7F5A9F9B4D04D11" modified="2016-11-30" version="1">MKNSEPASGDNVEAGVDKFKEFAQQASLDQDSIVQEVVELLQLAATTNSTEEHKTEGAYGEEDKHYFIDINFSIFASDWEKYEEFMERTRHEYGFLNDDQYKNLRRKILQSFLQIPNIFATKEFRSEYEQVARENIAKEIDTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTB1</accession>
    <name>A0A1D2MTB1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 4E type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000559">
        <property type="protein sequence ID" value="ODM96246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTB1"/>
    <dbReference type="STRING" id="48709.A0A1D2MTB1"/>
    <dbReference type="OMA" id="HIGRAYK"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF18">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="239" mass="26415" checksum="D355073D13C9A2B6" modified="2016-11-30" version="1">MSMVDDLRKPGATPDDDVDDDEDLTPLEVSPTDHRLQYTYGLWYIGKTNYQQYDLTLKKIGRFASVEQFWALYSHLENKLGGQWLVRLNKGLAARCWENLILAILGEQFDVGDEICGAGVSMRQKKDCISLWNRNAADKEATEKIRDTLRKVLNLPSHITLEYRYHKDVLQWVNTRDAKDLGEGGQSSSSQSGGAGGGPPLTPGGRPRPPSPTTDSISRSLDRGAPGLSSTAANIGSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUP6</accession>
    <name>A0A1D2MUP6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">adenylate cyclase</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_10146</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000529">
        <property type="protein sequence ID" value="ODM96534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUP6"/>
    <dbReference type="STRING" id="48709.A0A1D2MUP6"/>
    <dbReference type="OMA" id="SRDEFKC"/>
    <dbReference type="OrthoDB" id="2107370at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000008">
        <property type="entry name" value="Adenylate cyclase type 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="13">
        <location>
            <begin position="13"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM96534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="28887" checksum="FD1C31BA417A40D5" modified="2016-11-30" version="1">MSDLYSQAFDKCAVMFASIPKFIDFYSEIRNSGIECIRLLNEIVVDFDELLDERRFSSIEKIKTVASTYMACSGLHPSDQADSGDKDNCQHLCTLVDFALEMKDKLEELNRHAFNNFKLRIGARKPCFDVWGNTVNEASRMDTTGIPDSIQVTKDAAQILEKNGFQLEYRGLVPVKGKGEMETFFVRGRAPSRFRRYEQGSSQNRKSLAAVVFGMVQARRRQTIRGAKGPADILTSPSPKATRAGSYRRSDNNKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV60</accession>
    <name>A0A1D2MV60_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selection and upkeep of intraepithelial T-cells protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000481">
        <property type="protein sequence ID" value="ODM96977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV60"/>
    <dbReference type="STRING" id="48709.A0A1D2MV60"/>
    <dbReference type="OMA" id="LWFKEND"/>
    <dbReference type="OrthoDB" id="6431884at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="35"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="17855" checksum="A51BCC5AE531F8FE" modified="2016-11-30" version="1" fragment="single">MAKYFKQFIEESVPMNMIIWKPTTLKDMIRYIAVPEIEVESLVGGRAEFPCDVNPLPDRRDDSVHMVLWFRDDFGKPIYSLDVRGKPLEYARHWSSDKLFGTRAHFRVVSDPTKPARLVIENVKLTDEGVYRCRVDFRNSPTRNFRFNLTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVV3</accession>
    <name>A0A1D2MVV3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000463">
        <property type="protein sequence ID" value="ODM97210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVV3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="440" mass="47676" checksum="AD23EB8DAAE54AD4" modified="2016-11-30" version="1">MSVNAVPGIPIPPPQPHSTNTSSSNSFSTCCEVDDGGGIGALSSDDDEFTNNGTVVADDVTFISNPHEYKSNTCKSDKSSKSTMNHKRVSNGLKSYSLKTWYRAIGKSKWSSPLTSLYLTINHGKRKSREDSLDQDGDNGLDLESPHSRHSSTSRYSDDENKISISVEYPETHCTKSIVVVGDDVQVSPSPDCNNNEFKGQGTLTYGKNTLPLNTRTLTLNKSALPVPISNSFAGSNHSLSGSSKNTLSGGSGGKNTLSGGKNTLSGGKNTLSDSKNTLSSGEKNSRTLTLKKGSYTPEKQHDRLRRRSPSKSVLFHRHLPPPPLNSSGNNVHSSNSPSPTNSYEHGGAISPTTHHGAPHGYQRSTSLSSPTQTHDPYKHSSTRHASIDSSDTTGTYHDDGKHSLLQFAMKYFRQDKFNLANALHSNNEQKPSAWTWRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVW6</accession>
    <name>A0A1D2MVW6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000474">
        <property type="protein sequence ID" value="ODM97092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVW6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="19304" checksum="59D535DC7C0AA29B" modified="2016-11-30" version="1">MRNAYSSTKSRLVLLTRNFGNSWSKMAQNLWKWDSDSESEGNDAKPNDKSSEIKTSAQPKLATSVPMNTGRFQVVAVPRSTCRGCYFATTTKYVNAHVKSIEKIQAQVEKLGVGDAENETSTTNVSDSVEGRASTGKRVSRLPPPPSNLMDDSEEELIFEFDNNSFFGSKPLNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWE5</accession>
    <name>A0A1D2MWE5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endocuticle structural glycoprotein SgAbd-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000452">
        <property type="protein sequence ID" value="ODM97346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWE5"/>
    <dbReference type="STRING" id="48709.A0A1D2MWE5"/>
    <dbReference type="OMA" id="CAYAQHQ"/>
    <dbReference type="OrthoDB" id="6371055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF205">
        <property type="entry name" value="CUTICULAR PROTEIN 97EB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904648" evidence="3">
        <location>
            <begin position="18"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="261" mass="29422" checksum="59F5D9FCBE0D6A62" modified="2016-11-30" version="1">MFKLAVIVFGVLAVAQAQRAVPRGRSIDNERVATTPVPILRQINKVNEDGSYTYGYESADGSYKVETKTKEGEVQGKYGYYDDTGALREIEYGASRQGFNPSGTGIRSPSSAPAMSYDPIDDSGFYDPERYDRPFAYNRNTEIVPEQQQQTQVRRPASGRRPGSRRPKQQQNFAQFEQNYAPAPQPQQQQQQVQHQHVVNYQSAPQPAPQPQQQQYYQPPPQNYYQAQPTAPPFSHAQQFHGHPARNIDINTGSYSVNYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWL2</accession>
    <name>A0A1D2MWL2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000477">
        <property type="protein sequence ID" value="ODM97045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWL2"/>
    <dbReference type="STRING" id="48709.A0A1D2MWL2"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="163" mass="18811" checksum="FAD5A8B07A7E5B2B" modified="2016-11-30" version="1">MDYSTYMTVPTALQFREEAGGEAAIMKYNHDLAYNGGKRMAEMFGTDIMQDENQIGSMVDVRLPVNTPDDPNLNDEWWIDEQLYNHTETYSSVYKHDGRWYTRVSAQIYNDMSDFEFSARHFLDICNELNGSPKQDSSANVITTGINMQFFTLVLLLLMSAWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ04</accession>
    <name>A0A1D2MZ04_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Synaptosomal-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Synapse</location>
            <location evidence="6">Synaptosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SNAP-25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000373">
        <property type="protein sequence ID" value="ODM98218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ04"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ04"/>
    <dbReference type="OMA" id="PESQEMQ"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031629">
        <property type="term" value="P:synaptic vesicle fusion to presynaptic active zone membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016082">
        <property type="term" value="P:synaptic vesicle priming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000018">
        <property type="entry name" value="Synaptosomal-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000928">
        <property type="entry name" value="SNAP-25_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF14">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00835">
        <property type="entry name" value="SNAP-25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0770">Synapse</keyword>
    <keyword evidence="2" id="KW-0771">Synaptosome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="104"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="168" mass="18549" checksum="D89B343DE194A380" modified="2016-11-30" version="1">MYAKEAGIRTLVALDDQGEQLDHIEQGMVQINEDMREAEKNLQGMEKCCGLCSLPCGNKSEFKEDAGTWKGNDDGKVGNGQPQRMGDQNGVPAYGGYIAKITNDAREDEMENNMEEVSIMVGNLRNMAIDMGSEISNQNTQIDRINLMAGSNEVRISMANERANKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZD6</accession>
    <name>A0A1D2MZD6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">IF140/IFT172/WDR19 TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08270</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IFT172 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000357">
        <property type="protein sequence ID" value="ODM98407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MZD6"/>
    <dbReference type="OMA" id="LKRTIWQ"/>
    <dbReference type="OrthoDB" id="2186662at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722">
        <property type="entry name" value="IFT140/172-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722:SF2">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="9">
        <location>
            <begin position="1059"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1700" mass="194710" checksum="B81064AEC4405F86" modified="2016-11-30" version="1" fragment="single">DGAQSYTVTCMAFSPDSTRLAVGQSDLIVYVYKIGEEFKMKKSIIHKYQQPAPVTSIVWPKEYEIFCGLLDGKIRQCHTVSRKGPKTRTIMSNESCNIALISNVWGTEMIASFTDGRIAVFEIGDEDVVSLITVIRHSCPPTAVAITNDAILAGGYDKKLSIYDKRSGEVKQLFDYSTDNDEHEFACAAANPEGKSIVVGSYNKLFVYHYVARRKEWQEGNAQDFDSLYMVSSIQWRKDGSVLAVANNIGALYLMEATYKRTRHERFEMIYSSPSSIILNIFDPQKSISVKSRFACEILEAKLSKDGNFAIVKTGDTLLLCEVATGLTSEIPWLYSDKDKERFYFEYENVCVIYYESELTIVEYGRDETLGSFRVDTMNTHVVSIRVCKRYFGNEELISKKLAYLIDPRSITIVDLQYNLTVGNVGHDTKIDWLELNESGTKLLFRDKRSRLYLYGVDSSNKLPLVMACDFVQWVPACDVVVVQTNGLLRVWYNLETPDVTVDHDVSGHAVAVYKKSEREPTVVQLEDGSSTIEVPLDEGRIQFATALESGNLFQAAWHLEDYDMSPEVLAMWQRLARVALENYELRIAQKAYAVLGDVPRAKFLYNTIEMIRGPGNTPEQWYAPGWWKEHQMCIARRNILLGRIKEAEIVFIRHMDVDNALFMYKIMQRWNEAITLAKVKNHPQLSELLTEFTQMVYRDREWYEAGRFFENVAMFNHAIFHYLESGFPTHASRCVGKSKMKLEDDLLERLGNTLVDMKFYETAGDFFKTTGQRGRALDVYRKGRCFDKALRLAKRYYPNEVTNVEEEWGDWKFSLRDVDSAGHHYIEAGNLYKAVECALETRQWKKAAQIIAVMKDDGNINKYWIRLGDSYASEEEFSEAENSYLKAESPKKAIDMYAAHEKWDDAVRVANNNNYSRDEMKKDYIQYAVQFMEQERYPQAEKLLIAMDEIDQCIGMYAKAKMYDQVLRIVKEHHPSHLDKTAAHVAEMFLKENDMKSAVSTFLACGLWQNVVGLYQDRGLFSDAHQVAAQYGGNKAATYVVFSWAATLQPDAAVKLLNKYNCFEEAISHYNNHGNVELSAELCRSGSHEKLQEILYQMAMQAESKGDLENAAKHYLEGGMNFEAIEMYLRRELFDVAMDIAKRTSKEAVHKVMIAQAEHMFYARNFIAMENLLLRAERPEHAVNLYKRANMWNEAFRVCKDSCPHLMEQLQREFDTSDAKMTMHNDAESIIEQAKRYEKLGEYKRAVECYLQLTPDMMEGNPSALAKCWVRGGELAVKFLKRSQAEYVVQTVAPLLMGIHMHLEAANLYSLLGFKELAVETLIAGKMWDEAKDLASEVSPEMEHYVTDQQTKMLKSVGHVDELENLNLAAALDLLCEQGQWKKCMEKARRQNASVFSMYLAKYITHLLKHNQPEEAMSVYAEYGPPADKQHYALYKAIAMMIFSNVQHDRVEIWIRLRDILFDVINGMKVTPDSTSKYKTQLEKILWCAHYYVNRNAFSKSQGMEILATKISISLLRYIGTVPAEKAFYEAGLACKEREWKNMAFVFLNHFMDVYDAIEDGVGNTVDLDNTDFVNTDIPLEVELPPQHMVPKQCYDDSREWILAASMDPDIQQALRIDERGVFEASLVPGPSGLACDQCLLSGYPVLGPRVSFRAPNRAANRDDWNKMVMAVKSTHNPELQNIIEFINDWCGANPNYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZD7</accession>
    <name>A0A1D2MZD7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000361">
        <property type="protein sequence ID" value="ODM98360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZD7"/>
    <dbReference type="OMA" id="WMKSSIT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="22577" checksum="7AB79B7953A53773" modified="2016-11-30" version="1">MFQLRDKNCHWVLGLINVSNGICLIVLSSLFLNQTWHLLKQQRNQAKEFAHVHEKPFKNSNWMKSAIPLVISSILGILIGVIQTIALVISLLMDNSKSYHQQRKMGWLVWLAAGMFIFILSTLSFGLAVILKAHEYRNPKDSVSFWTNYRFNSSELIHNVEGHAFCSALAWNCAVLLASMAIVAAKTFRQRAPHILLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N003</accession>
    <name>A0A1D2N003_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MFS-type transporter SLC18B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08073</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Vesicular transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000340">
        <property type="protein sequence ID" value="ODM98602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N003"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF26">
        <property type="entry name" value="MFS-TYPE TRANSPORTER SLC18B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0532">Neurotransmitter transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="626"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="780"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="818"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="847"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="872"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="913"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="940"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="982"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1028"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1059"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1084"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1122"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1158"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1279"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1316"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1347"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1371"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1408"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1441"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1489"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1522"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1554"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1581"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1625"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1654"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="299"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="782"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="1281"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="748"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1204"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1708"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="225"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1208"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1225"/>
            <end position="1239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1776" mass="190841" checksum="982489375D4FBB94" modified="2016-11-30" version="1">MSNSPSSRAQQTSSFSPAAQQSPTVTSSAASSLSTPPDRGNRDEETKVSTKQQTPQPPSPKTSTVATLTNPTESVPATTTPSQEKTEVKKSAAKMESTDAPPPKADKPAEKVQLEKSQQDQPDKKDEGKAVPDTLEASKPIEKSEDAQPQSKKVPEEPKKSTEKEPELPERPQPKADKPSETIESKVEEALGKAQPRPTAKTLVVSPPKDAERLTDAPLSVDIEPSTSTSGSERRPSSATSPGFAYALSTPLGKPGYIGGVGLSTEEGETLTRGLERRESAIAAVGTAVKGFTKRQWALLMMFGLIDLLSSITIALQAPFYPAEAEKKGATATEYGIVFGIFEFTVFLTPIWNIDEQTRTKNSFHCWNFCIFICSNMFWVSSTSKYYAILKEIKLHNCYNDLCHEISRFLDRIDDHTWFITLCFICRIFEAVGCAGFFTATFTIIACEFPESVATTFASLETFFGLGMIIGPTVGGLLFGIGGFPLPFFVVGGCLLVTGFLSSFLMPKIDKVRDEDGNEQVGYGVWTVLKIPSVALAAIGVATTSLTLGYVSAILEPHIRSFGLTPLQTGLVFIVNGGVYALMAPIFGYLCDWISRPVYLMIIGNVLIFISFLLIGPASFIPFDTILWVTIIGLAIQGVGFGCGLVAGFIVGLKDSMAYGLPDNMATYGVASGLWTSAISFGAFVGPSVAGVLYDTVGFRDGSYLILGITFAMGTILSIHTFATRSRASASDSEAQPLLRPISPLTSKKEVAAADPKPSSYGSTSAGSSSGTGGDVPKQWFLLLIFSIADLFAGIVYSLQAPFYPQEAEKKGATPTEYGLVFGVFELTMFLAPIYGKFVMSRIGPRVVFNAGIFITGTCCVLFGLLDQIQDRFWFIGLSFLIRILEATGNAGFSTASFTIIACEFPDSVATTFASLETFFGLGLIVGPTMGGGLYQVGGFILPFAVTGALLFLNATMILIFMPKSTSAAEITDEKSSSGFTVLSILRVPGVMLAACAIIVSALSIGFLSSSLEPHIRQFGLSPVETGLVFVINGGVYAISAPAWGWFCDTTSEPKLVTLAGAILITIGFLFIGPVPFIPIETKLWLTCVGLMIQGFGIGAAFVSSFILALRHSIAAGFPDNVATYSVVSGMWASVLALGLFIGPSIAGYLLESVGFQWGSVFVCGSSFILTIAVIAFLLFTDKTKAYTRPGYQDTSERARLIEEVGDTNENSSEPRADTPTGTRPSHSSPNSSKLSDSPFAHTCSISPLNPNPSQPVTAGRRPQKKNRKWLPDFTSRQWLIFTVFIGTNFLAGMVYNMKGPFYPQEAESKGVTPSQYGFVFGIFEFVKVFASPLYGKFMNQLGARKIFIGSLYIVGICSILFGLLDEISDPTAFFVCSLLLRVVEAIGSSGYSCALFSIIAKEFPGSVATAFAVLEACFGVGLIIAPPLGGVLYQLAGYPLPFITVGLLIFTVVNLICVVMPRSFTVRDSEGRATEGFGVWKILKVKGMLFAVIGVLTGACSTGFINATLEPHLRQFGLTPFQTGIVFAIYGLVYAMTAPAWGWICDRVREPKYITLFGAASNFIAFLLVGPAPLFQFDTILWVTCIALVLHGLALGAIFVSLFILAFSYAVASGLPNDMKTHSVVSGMWTSVLSLGMFLGPSVGGILLDRIGFRWGSLFALSIMACLIVLVLTYLLLQKCAIRLPTNPDETDVDSANTKETEPLILPTPLPNVSETPDDDDLQSQMRQSASSNYGATVAITQLFQSLENTNIIITKLTTNIYDSMSQEHELRVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1G3</accession>
    <name>A0A1D2N1G3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synaptotagmin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000297">
        <property type="protein sequence ID" value="ODM99136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1G3"/>
    <dbReference type="STRING" id="48709.A0A1D2N1G3"/>
    <dbReference type="OMA" id="GHITCPL"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048791">
        <property type="term" value="P:calcium ion-regulated exocytosis of neurotransmitter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000140">
        <property type="entry name" value="synaptotagmin-7 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001565">
        <property type="entry name" value="Synaptotagmin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF344">
        <property type="entry name" value="SYNAPTOTAGMIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00399">
        <property type="entry name" value="SYNAPTOTAGMN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="143" mass="16891" checksum="9E742EA459577422" modified="2016-11-30" version="1">MAFWQNRSISLVDMYIDNTDSTDNVGQINFSLEYDFENMTLILRIIQGKDLPAKDISGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETLYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVKNRTFTDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N281</accession>
    <name>A0A1D2N281_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Aminopeptidase</fullName>
            <ecNumber evidence="15">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_07304</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13 15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="15"/>
    <dbReference type="EMBL" id="LJIJ01000285">
        <property type="protein sequence ID" value="ODM99382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N281"/>
    <dbReference type="STRING" id="48709.A0A1D2N281"/>
    <dbReference type="OMA" id="MMEYVAI"/>
    <dbReference type="OrthoDB" id="275509at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016285">
        <property type="term" value="F:alanyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15 19" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 13 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="18">
        <location>
            <begin position="16"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="16">
        <location>
            <begin position="238"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="17">
        <location>
            <begin position="537"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="14">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00052895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM99382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="872" mass="99152" checksum="DA4FBA0BE8200814" modified="2016-11-30" version="1">MAEEKPFQRLPTNVTPVNYDIEITPNFGDFTFKGSQKIDLLITAETKEITMNAADLTVRNGVFLDNASGAKINARHVEFDTPLETVKFVFDPPLKSGSAGVLSMEFDGSINDKMKGFYRSKFQGPNGEDRYNGVTQFEATDARRCFPCWDEPSVKATFDIGLVVEKEKVTLSNMPVKATSPVSGSDNLHLVQFERTPIMSTYLVALVIGDFEYIETKSTDGVLCRVYTPPGKLEQGRFALDVVARVLPYYKEYFGIAYPLPKIDLVAIADFSAGAMENWGLVTYRETCLLIDEKQSSSSNRQWVALVVGHEAAHMWFGNLVTMEWWTHLWLNEGYATFVEFLCVDHLFPEYDIWTQFVTETFIRALELDCLENSHPIEVPVGHPSEIDEIFDDISYNKGACIIRMLHDYIGDTDFRKGMNLYLTRHQYKNAFTEDLWAALEEASGKPVGAVMGTWTKQMGFPLIRVLASRQEGTNRVIELSQEKFCTDPCKKTDGNYHWMIPLTFCSSSNPAKPIYSTLMDSQSMTVTIPNVSENEWVKLNPGTIGFYRVQYPPEILEQFLPAIQQKVLPPVDRLGLLDDVFALVQSGQTGTTNVLKLLDAFKDETNYTVWSSISNVMSKLNLLLQYTDYHDQFKAYGRKLFSSIEEKVGWEAKPDESHLDTMLRTLVLLRMTTFGHEKTIEEANKRLKQHVSGEKTIIADLRTVVYRGVLSVGDESTYNALLKLYHESNMQEEKDRIGRSLGAIKDPELLRKVLEFSISNDVRSQDSVFVIISVGMSKTGREIAWNFFKENKELFRERYPGGGLISRLVKYVTEDFVTEEMATEVEKFFIENSFPGTERTVQQSIESIRLNGSWLKRDENAVRQYLQTVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3C2</accession>
    <name>A0A1D2N3C2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHK kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000271">
        <property type="protein sequence ID" value="ODM99554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3C2"/>
    <dbReference type="STRING" id="48709.A0A1D2N3C2"/>
    <dbReference type="OMA" id="WISENFI"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="134"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="405" mass="46757" checksum="A219EDB1D0507549" modified="2016-11-30" version="1">MSSDSFINEEFLQRLLGCKIKSYTCNVGTKPGDNYLSTIYSVKVVLCDDSLKSILVKCYPENVAKREFLDNTSIFSTEYLIYDQFLPALNQLVDTCGDDKSTFAVNVASFYGGNIIGIKSTRFDAEPWISENFIVLEDLRTKGYKMLDRRKGLDLDHVLLTIKQLANLHALSWVYKRRNGLHLLVNKYPYLKDVMYKKENEAGWKPVLEGLNRNALEIIQQEFGPESDIFLKLKALLSKDVMDMIRIYLNGTGIDELVAESLLRIKPDGPIPFADDQWLVATHGDSWINNLLFAYNEEKTPKSVVIVDHQTFRETCLTVDLAYLIYSSTPVSLRKQSVPVLLRTYFDHFVEICQKLNEKPPVSFTFSNFERRWRRARIYGLLMSINFITFIHKPDEPEHTQKQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N471</accession>
    <name>A0A1D2N471_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">O-phosphoseryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5 18">2.9.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 18">Selenocysteine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15 18">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16 18">Sep-tRNA:Sec-tRNA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">Ocin01_06831</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 18">Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H2O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:25041"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="Rhea" id="RHEA-COMP:9947"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78551"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18 20">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 18">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="18">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the SepSecS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.2" evidence="5 18"/>
    <dbReference type="EMBL" id="LJIJ01000252">
        <property type="protein sequence ID" value="ODM99844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N471"/>
    <dbReference type="STRING" id="48709.A0A1D2N471"/>
    <dbReference type="OMA" id="MSHANDY"/>
    <dbReference type="OrthoDB" id="10263545at2759"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00898"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098621">
        <property type="term" value="F:O-phosphoseryl-tRNA(Sec) selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001717">
        <property type="term" value="P:conversion of seryl-tRNAsec to selenocys-tRNAsec"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019872">
        <property type="entry name" value="Sec-tRNA_Se_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008829">
        <property type="entry name" value="SepSecS/SepCysS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03531">
        <property type="entry name" value="selenium_SpcS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12944:SF2">
        <property type="entry name" value="O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12944">
        <property type="entry name" value="SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05889">
        <property type="entry name" value="SepSecS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017689">
        <property type="entry name" value="SepSecS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10 18 20" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 18 20" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="12 18" id="KW-0711">Selenium</keyword>
    <keyword evidence="8 18 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 18 20" id="KW-0820">tRNA-binding</keyword>
    <feature type="binding site" evidence="19">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
        <ligandPart>
            <name>tRNA discriminator base</name>
        </ligandPart>
    </feature>
    <feature type="site" description="May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate" evidence="20">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="20">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR017689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR017689-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ODM99844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="515" mass="56579" checksum="BC51A301E03D8B1E" modified="2016-11-30" version="1">MSYPAFQKVGKKLLPTPLLQHATESANSRNKQFQILLEQRKWPEEGWDEQTIEIFLNELSAMDTNNFMTRPSGVGEREGRTYSSLVRRRAYGLSHGIGRSGDLAESQPKAAGSSLMSSLTNDLLLDFLQTNIGKDVKEACLFPMATGMTMTLILLTLAKLKPGAKHVVWLRHDQKSVFKSILTAGLTPIIVDPVLSHDKIQLETNVEGVESAISRIGRDNILCIITTTSCFAPRSCDNLKSLRKFCFGSRVHHDNCESTKCSRHFGGDQDSCGTNVIYHVVNNAYGMQSRLILGELRKAMSHVDLFIQSTDKNLLVPVGGCIVGSPIISSPKNSVSLLTKVRKNYPGRASSYPASDVLITILSMGKKGFKSLVEQREENYKYMKTKLTEVSKKHNEQALSLSGNDISIGFSLGSVGPSQDVLTSVGGMLFKRNVTGARVVTTEDVKTIDGYTFKGWGAHHPEYPVPYLTAAAAIGMDKEEIDDFIGKLDECIGQVKSQDKLVKIGVTETNNNALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N482</accession>
    <name>A0A1D2N482_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Solute carrier family 22 member 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000237">
        <property type="protein sequence ID" value="ODN00042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N482"/>
    <dbReference type="STRING" id="48709.A0A1D2N482"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="542"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="576"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="604"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="686" mass="77872" checksum="77032A25A0156D25" modified="2016-11-30" version="1" fragment="single">MAHHDIFSDELLSTDAAEIESPKPGPSKPSCLVAAAAGNESDEKEEESRWPYKIKNVKVTFDPNPEIIQYKECRERRLHAIAEREREDHFVRPHRSRSAYSAFLRGNAPSLSTFDDFLSIVGSMGRYQHRAIFKITCPVTVFQALLTMQLMFLYATPDHWCAPLEGRPFRVQVNNITAWKLDHLPYTIDDNGDFNFSKCSIYTNATIHDEVNTCVNGWEYDQSTYIRSLVTENNLVCGKELVIEHASVVLAVGSFSGPFFYGGVADKYGRKMTYILIALMNFIAHIILSVFYKEVGFYFVALFMKASTYYSLVILPVLWAMEVTKEEVRTHICALTGVANFIGTATVTIFTYQFSDSLVITAMGIGFSAAVFALCLCMWESPRWLFVMNELDEAAEGLREMAVQNKLTNKNSILTKSYMFDTVRLLSTAKAQQVTPTYSDFHFLEMFCKRNTLLIVLRLLFLWFAIGVIDKTLELNLPPVVSNIYLNFLFMRMSQLPGFIAAVLLSHLMGHRDTQVILHAILAFVLLATGLVHVYIPMAHTHMALGVVLRLVFSAIVLNCFIHTLELTSTNVRSSFLGLCVSVSFFFETPIPFIYFMVRHSYGIPYYVCAVLSLISAVLTVFLPETMGHPLPDFLDDVEEKWCEKFGTYYRNLWVIPLVATEDGNDNQAFEMEETITYENINNSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4S8</accession>
    <name>A0A1D2N4S8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Microtubule-associated proteins 1A/1B light chain 3B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_06409</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000219">
        <property type="protein sequence ID" value="ODN00278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4S8"/>
    <dbReference type="STRING" id="48709.A0A1D2N4S8"/>
    <dbReference type="OMA" id="MNMYQLY"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000149">
        <property type="entry name" value="microtubule-associated proteins 1A/1B light chain 3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN00278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="132" mass="15304" checksum="965F92CD1FDAD88C" modified="2016-11-30" version="1">MIPLYQPGQRVREVEQVRKEYPDKVPVIIERYAHENQLPPLDRSKFLIPEHVHVGELIKILRRRLQLNSSQSIFLIVNGRNLPANASTFAEIYRNEADPDGFLYIVYASHETFGSSSPQECAMTDYNNRFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5L4</accession>
    <name>A0A1D2N5L4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster assembly 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000198">
        <property type="protein sequence ID" value="ODN00569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5L4"/>
    <dbReference type="STRING" id="48709.A0A1D2N5L4"/>
    <dbReference type="OrthoDB" id="1938621at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011:SF1">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="89" mass="9994" checksum="31C1F3FC271A41D0" modified="2016-11-30" version="1">MRYVKPSFEVIHKDQKESSGAALVVIDEMSLDIIQGSTLDYERELIRSAFRIVNNPHAEQGCSCGASFNMKIPITFGMSEWVNVVLCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6B8</accession>
    <name>A0A1D2N6B8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000185">
        <property type="protein sequence ID" value="ODN00813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6B8"/>
    <dbReference type="STRING" id="48709.A0A1D2N6B8"/>
    <dbReference type="OMA" id="QFHRLEL"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="306" mass="34637" checksum="FC1F5439C2D1A9D2" modified="2016-11-30" version="1">MTIEGVPSLKLSGYIDDTPGSSSGTAVDSKRVSGSKVVTSSVTISSGAEVVTSSVTISSGAEVVTSSLVEVVQFPEWGLQFLVEVVQFPEWGLQFLVEVLLFPVEVLLFPVEGLQFHRLELQFHRLELQFHRLELQFLAEVVQFQELMLQFQELVLQFQELVLQFQELVLQFQELVLQFQELVLQFLVEGLQFLVEVVQFQELVLQFLVEWLQFQVEVVPSQELELLFPVEGLLSQGLVLLFPVEGLLSQGLVLLFQGIQCQELVLQFPVEGLHFQELVLQFPVEGLLFQELVLQFLVEGLLFQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N705</accession>
    <name>A0A1D2N705_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_05676</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMTC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000176">
        <property type="protein sequence ID" value="ODN01012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N705"/>
    <dbReference type="STRING" id="48709.A0A1D2N705"/>
    <dbReference type="OMA" id="RVICEIQ"/>
    <dbReference type="OrthoDB" id="19588at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052346">
        <property type="entry name" value="O-mannosyl-transferase_TMTC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013618">
        <property type="entry name" value="TMTC_DUF1736"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44227">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44227:SF3">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08409">
        <property type="entry name" value="TMTC_DUF1736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 16" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 17 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1736" evidence="18">
        <location>
            <begin position="214"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="388"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="489"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="596"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODN01012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="642" mass="73950" checksum="8F5CD954B97AEC33" modified="2016-11-30" version="1">MDITHRLSHKSFRPLTTLTYRYRFMNNKMINLMKWNVHNIIAKFNFRLDYYIWGHNPFPFHLLDLLIHGINCVLVFIFLSKCVKPKSELISSKGESLAFWGTLLFSVHPVHVEPLGAIVGRADLFGAMIFLGAFCFVNDHRSYKGVIFISMFSIVGSLFKETAITLSVFILLLELWNTWIVSPDEPKRSSTLRCFLTVTLAGSFVVWRLWLQDGPPIFQPFDNPPAFAPSLFSRVASIIYIWVLNVFILLNPVWLCYDWSMGCVDIIESFWDLRVVVVILFLIVCLRLALLAFKHRLIMLSILIFASTFLPSSNLLFTVGFVLAERNLYLPSIGYCIFVAYVFLRLEQKKCLIFLIIIFYIRSCQRSMDWMNQGTLFRSGLQVCPNNAKVHYNLGTMYGDLSDRKSAEKSYKTAISLKGDYYQAMNNLGNLLRVNNELKEAEIWLRKAVEIKSDFAAAWMNLGIILSTSNKSEALSCYHNALKFRKSYPDCEYNLGNLYLDMGDKENALKAWERATSLKHTHSQAWINTVILLEQEGKLQEARETAVRALQVLKSEHTLHFILGNILGKLSEFESAKTSFEQAIKICSQLNKRIPPKYFSNLGVLYHRWGKKSQAIELYQKALIIDPHMTSAKKNLEMLMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7A8</accession>
    <name>A0A1D2N7A8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000170">
        <property type="protein sequence ID" value="ODN01122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7A8"/>
    <dbReference type="OMA" id="RICECDY"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905154" description="Chitin-binding type-4 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="2">
        <location>
            <begin position="21"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="24378" checksum="0517A75DCDD9C027" modified="2016-11-30" version="1">MKAITLIFGALALATVEGHMRMLEPASRTSMWRFPEFAYLNPTETAIDDQFWCDNVRQFEQDTRCGVCGDPVQDAVPRPAEYRGQFWRDVTVRNYTAGATIQVHLESYAPHGGGIEIHLCDTVPETESCFRKLTLGNGDTFWPMRLGDGDFDIQTTATLPAGVTCDRCVLRMHYRGAQHWGNCDSSRTCECDPNSGNPPGGMGCSEQQTFRACSDISIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8G9</accession>
    <name>A0A1D2N8G9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor A, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000147">
        <property type="protein sequence ID" value="ODN01559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8G9"/>
    <dbReference type="STRING" id="48709.A0A1D2N8G9"/>
    <dbReference type="OMA" id="KLTAMEP"/>
    <dbReference type="OrthoDB" id="5550281at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="42"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="42"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="235" mass="27245" checksum="BEB47012CD0A84DB" modified="2016-11-30" version="1">MSSWITNGLKTLRIRVGGAVGSVSQPRYFGAQVTEVKIPPRPKKPLTPYFRFMGQVRAEVKNKNPNLKVTDLIKLMGQQWDRLDESAKQSYISAYRNEMQSYASVIEKYKQSLSPEQKEAQQQMKLDSQLLREKREKKRRLKELGKPKRPASPFFLFLSSKVTPGSKIADYQDAAKKLGEVWKTMSDAEKEPFAAKYKEDLRLYEKSMTKWEDKMIKQGNDDVVRESKSRKVKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8J6</accession>
    <name>A0A1D2N8J6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger protein-likeSTOP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000161">
        <property type="protein sequence ID" value="ODN01296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8J6"/>
    <dbReference type="OrthoDB" id="6513424at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34153:SF2">
        <property type="entry name" value="SI:CH211-262H13.3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34153">
        <property type="entry name" value="SI:CH211-262H13.3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="28666" checksum="2DEB44089DB9BA79" modified="2016-11-30" version="1">MFAIVELTAERACEVVPKTWIRHNKCAWPSSNDPAKIRNLVNKSKPPKKSWKHHDYKVLSEYETYELALENIDTFMRDSDLSDFETAKKKKKTSMLCFGLVSNPIVPAAVGSTYEPDDNDVFLEPMTPHLHLVNPNGADSIEQSNTSPNTPVVVNCIDPTPVVTGIAEIKLTLKQILDILQNLSERIEKLENSEGGKTTALVEDALDGTVFNLPITSQELLKDLEDDLSANQMRKQQLIQFFYYKGGSSILEALKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8M6</accession>
    <name>A0A1D2N8M6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_05099</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000146">
        <property type="protein sequence ID" value="ODN01602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8M6"/>
    <dbReference type="STRING" id="48709.A0A1D2N8M6"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000322">
        <property type="entry name" value="GDNF-inducible zinc finger protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="205"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="244"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="272"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="292"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="423" mass="47867" checksum="7F4E9346177B86AA" modified="2016-11-30" version="1">MESTASENGSVDTPVKVRRKPGPKPKCKTTNPTSFDCPNCDAKFPSKDLADSHAAVHNNDAYECGQCDKLFSNFEDLKTHFIALHTVQGTCTTILGLEILQESHNNATTSTSASQDNSYVCEYCSKVCANKSAYDSHVRTHSNEREFKCDSCPKSYKNPHELTIHKRTHTNERPFACPEPGCGKSFTIRRSMLDHQRRHTKAFRYYCEVSGCGKGFITKQDRDRHEVRGHIPVEERPELPGEKTQCQVCKKWISQKGQMKEHLRTHSKEAPFVCHICGKGFKIKSNLNVHLKSKKHTGEPVIQRGRGKKAVAKAKAKKKQETDSDYELDEEEDEQEDLKPTPPVEPPQPSVSLPQAHFPMYVHSSPSKIVHTIQNQANSNQHVYQNMPALMPQFNQVPAFVHQVQPNLQLPVLTLHDPFQTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8P4</accession>
    <name>A0A1D2N8P4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lysosomal alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05034</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000145">
        <property type="protein sequence ID" value="ODN01640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8P4"/>
    <dbReference type="STRING" id="48709.A0A1D2N8P4"/>
    <dbReference type="OMA" id="GEKWYDW"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00111">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.110.10">
        <property type="entry name" value="Spasmolytic Protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000519">
        <property type="entry name" value="P_trefoil_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044913">
        <property type="entry name" value="P_trefoil_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF131">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 31 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00088">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00018">
        <property type="entry name" value="PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51448">
        <property type="entry name" value="P_TREFOIL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905220" evidence="9">
        <location>
            <begin position="18"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="P-type" evidence="10">
        <location>
            <begin position="47"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="805" mass="91358" checksum="675F36457D3934A2" modified="2016-11-30" version="1">MVSVLAIFLILSREHFSSRITEGSEVHTAWKKTQIPAFASKTNKSPDLCQISDLKFDCHPEADAVENVCIKRGCCWNPVGPKNGIPWCYYPYGFSYFAFNNFTSTKLGLQGTAVSVRLSVRPKDVKNLNIQVIYETEDIVRIKITDAQSPRFEVPLDYATAEKKSEIKIISFDNHGMVFKFDSSVAPLIYSDQFLQVSTSLVSSYLYGIGETVDSLHKGGEWKRYVLFTRDQIPGYNRNLYGSHPFYMVVDNKGNSYGVFLANSNAMGCQWNDLDYMRNQDDFTVDPKKFAGLKDFVDDLHLRVGKYRPYDEGLKMDIFIKNEEGRPFVGKVWNPKATVWPDFSLPNITSYWLNQLQDFRGKVSFDGAWIDMNEPSNFDDGEHNKGCAKNSLNNPPYLPQVTGGSLYSKTLCPLRSRLVADTTICIIYMEHKKQSLHTSKCGTCISYFKIVLGDLTNERPFIISRSTFPGQGRFGGHWTGDVVSSWEDLRQTIPQILTFGLFGIPLVGADICGFNGNTTVDLCKRWMQLGAFYPFARNHNTDDGIPQDPASLGPEVISASKETLTVRYSLLPYIYTSFFQAHLTGQPVARALFYEFADDASTFLIDSYFMLGSSVMIVPILEENYNKPTITAYLPKGWWYQHYFSEIIESLGEERQLTIPDNSIPILYRGGTIIMKQDPALNTQLSRHNKFHIHVFLSQDSNATGEFYWDDGVSNLPDTLVQYDHFTFNTEKNVFTMRKEFSGYDSSNMTLGSIEIRGVMFPVSSAVLNNIPYNYNYSEHDKTLKLDDLSLTGASWTDGLTLKWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9X5</accession>
    <name>A0A1D2N9X5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutaminyl-peptide cyclotransferase</fullName>
            <ecNumber evidence="4">2.3.2.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_04609</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as a glutaminyl-peptide cyclotransferase. Responsible for the biosynthesis of pyroglutamyl peptides. Might be more efficient in the conversion of tri and tetrapeptides in vitro. Might have a relative preference for substrates containing hydrophobic amino acids in vitro.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23652"/>
            <dbReference type="Rhea" id="RHEA-COMP:11736"/>
            <dbReference type="Rhea" id="RHEA-COMP:11846"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:64722"/>
            <dbReference type="ChEBI" id="CHEBI:87215"/>
            <dbReference type="EC" id="2.3.2.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutaminyl-peptide cyclotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.5" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000126">
        <property type="protein sequence ID" value="ODN02054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9X5"/>
    <dbReference type="STRING" id="48709.A0A1D2N9X5"/>
    <dbReference type="OMA" id="HYETNYP"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03880">
        <property type="entry name" value="M28_QC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000029">
        <property type="entry name" value="Glutaminyl-peptide cyclotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037457">
        <property type="entry name" value="M28_QC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040234">
        <property type="entry name" value="QC/QCL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283:SF6">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="14">
        <location>
            <begin position="122"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00057903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN02054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="382" mass="43601" checksum="09FE622BE7349D5D" modified="2016-11-30" version="1">MRVPFRKHVFLGVVVILPSIIYLVISQRQPAETVPGRKWFEDKYNHQMKELDAETYQKLVQDGDRVPFEPLLDPMLIPRVPGTANHARVKQFIKDHMRGLGWTIETDAFQDNTPHGAKPFENIITTLNPDTPRRLVLACHYDSKYSNDDSFIGATDSAVPCAMLLHMASTMQSMLTEHKNSAHNVTLQFIFFDGEEAFQYWTSTDSIYGSRHWGRNDNDMLVLLDLLGTPNPKLYSFFQETSHWHNSLVQTEQQLKRSQFWSGSTRQTIFQAKNHYGGIEDDHIPFLQRGVDILHVIPSPFPTVWHKTSDNREALDFPTISNLNKVFRLFVARYLEGFNGGNALPIITSTSNAVGQAAKPGIMQHFLNFFLNALDGARLPIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAF9</accession>
    <name>A0A1D2NAF9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_04443</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000119">
        <property type="protein sequence ID" value="ODN02241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAF9"/>
    <dbReference type="STRING" id="48709.A0A1D2NAF9"/>
    <dbReference type="OMA" id="CIYLCEY"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005705">
        <property type="term" value="C:polytene chromosome interband"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046972">
        <property type="term" value="F:histone H4K16 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140861">
        <property type="term" value="P:DNA repair-dependent chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000022">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000002">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="15">
        <location>
            <begin position="111"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN02241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="47461" checksum="0CC44C48869BB7C6" modified="2016-11-30" version="1">MFLVNKRLDGWVGEDRINFANVLRPIPTVDSGRITSPSTGRSSRAVSEASEVSLSTPSNSPRKKKKYNTSRVEVMPQLESPTTSQASGEDPTSPGSKGMSTSGSHKFDEKLLTKNVAMVELGRYRMIPWYFSPYPEKLVNGLECLVICEFCLKYMESVDRLRRHLQKCPLRYPPGKEIYRNGIISFFEVDGRKQPEYTRNLCLLSKLFLDHKSVENDTDVFLFYVMTVADNTGFHLVGYFSKSKISIENFNVACILTLPSYQKRGYGKLMIELSYELSKREGKLGTPEKPLSDFGLLSYRSYWSKTILDILCSYKKELTKSDAMKEEGDDDNDGDMIGMSIEQICDATAMQKDDVVSTLQNLDLLKYYKRSYVIVLTSEMMKTHKKKLKKEAAASKKGFPALKLDRKCLHWAPKCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBJ6</accession>
    <name>A0A1D2NBJ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Rab GTPase-binding effector protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_04057</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Early endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the rabaptin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000103">
        <property type="protein sequence ID" value="ODN02630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBJ6"/>
    <dbReference type="STRING" id="48709.A0A1D2NBJ6"/>
    <dbReference type="OMA" id="XDLKRQN"/>
    <dbReference type="OrthoDB" id="79940at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.730">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003914">
        <property type="entry name" value="Rabaptin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018514">
        <property type="entry name" value="Rabaptin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015390">
        <property type="entry name" value="Rabaptin_Rab5-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31179:SF7">
        <property type="entry name" value="FYVE-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31179">
        <property type="entry name" value="RAB GTPASE-BINDING EFFECTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09311">
        <property type="entry name" value="Rab5-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03528">
        <property type="entry name" value="Rabaptin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01432">
        <property type="entry name" value="RABAPTIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="17">
        <location>
            <begin position="731"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="650"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="87"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="247"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="333"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="448"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="661"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN02630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="803" mass="91450" checksum="3BBB49FCCCD64394" modified="2016-11-30" version="1">MSTEETSQGIDSETKDSSADEFTDATEEIVGGNGDTVGLSSPSPSVDNLMSKNSELALQDQIMTLQRKLVELDADFGAKRARFKELFMQKEDELAQERDSKSKLEADIKRLEDELNESKSQVTIAELQKNDIEIERQRYQSDSIMQRRKYEESIKELTTKYDNEIQRLKHVNSKLEANITEVRETLSPSSGFDGPGAVFSTVGQHFKKSLARKINSTMTASNDSLHEIDDGAKLKPTSTSKYAQEDAEMLRSLVVQLEEELVALKEKVRNSDEQLAALQSAQASLVKGNDALTIFLQGKDVQDVLTQLDDKLRTAQNGLEAEKSSRADLEMYVAFANAQKTLLQDELDKSKLELRDLKEQLDLERKRHDENCKRYEKISKMPLETVQAKLARLQELISQIRDPSSEETAKKLAELQVVSSSDESTFDGAGNPVPPAPCKECDSRQSQIDRLKDELHKSSQFRKDIEEESNTKAQGLQAQLNALEAQMGTYELLLHEVNTTSQQAMDNMENRLKRLQYERDSIQSKIESLELENDNLKGKHVKHSVAMQNEPISLPNDVMELQELVLKLREDLISVQIGKETVEGELQFLKDQMKMIEEEKTTIEEGLNSEISSLRDMLTESKHRCDGYEEDRRRLEKTINDVKTKLMASEAHSSKIYQSKKQSEDHAREKEVRYESLSRENHELQGKIGTLRKELNNSEDLQKDLISLNKSLQMELEALRCPETEVRWQHPDDISQCKTCKKGLHDPREKHHCKHCGRICCPDCISRTIRRGNRDYNVCGFCHTLLAHDSAPYFSTEPPHSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBM1</accession>
    <name>A0A1D2NBM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein timeless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000101">
        <property type="protein sequence ID" value="ODN02653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBM1"/>
    <dbReference type="STRING" id="48709.A0A1D2NBM1"/>
    <dbReference type="OMA" id="MEHYYEM"/>
    <dbReference type="OrthoDB" id="310853at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044998">
        <property type="entry name" value="Timeless"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006906">
        <property type="entry name" value="Timeless_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940:SF4">
        <property type="entry name" value="PROTEIN TIMELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940">
        <property type="entry name" value="TIMEOUT/TIMELESS-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04821">
        <property type="entry name" value="TIMELESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Timeless N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="537" mass="63673" checksum="51F59DB41CBA1CB7" modified="2016-11-30" version="1">MYLCMKDLILYLRRDDDDHSARRLLGQAQVLGRDLLPLFKYNHKEPKLWDLGLRLLVNLTHPALLLYDEEVPKNKKYLNYYNQLLGYLRTYKEDFVDKVVWKILAEKLRQLLNLEWDKRMEHDRITIERILIVIRNILHVPADPSEERRADDDTSLHDRILMVMHISGFEDLLLYAAVSETTQEFSVLILEIMSWMLREQTGEQLAKTQLARNEDDKIKDERELVRMREKEAVLKTIQLQKLPTRHSRFGGTFVVRDMKAPSGRDLLCHKPITSVTDLSLDSTKKRKRVASNRKPINDEDSTRRSTIPIRIILKDFCTSFLVDGTYNQMMSFVKDGIVRGRTEDNDETYYLWGMKFFMEFNRHHQFSVSYVSETMSTSTFHYVQTLLDRYQGMMVTDKEKIPFWSRRAHMALKAYQELLFSLLWMDRDEDESVKESSRVIKSNVFYLPEYRELCHGLLNTYDPVKLSKLYLKDLIETNHLFLKMLEDYSSQNRRIMIKGKGKRKKSTKVSNDRILIDEVLYYCTTVVVEDRDNSIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBT6</accession>
    <name>A0A1D2NBT6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Neuroligin-4, Y-linked</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_04128</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBT6"/>
    <dbReference type="STRING" id="48709.A0A1D2NBT6"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000156">
        <property type="entry name" value="Neuroligin-4, Y-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1065"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="498"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="62"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1130"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1164"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="324"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1171"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1208" mass="136516" checksum="07B4BCD36692FAD1" modified="2016-11-30" version="1">MQIQEGKPFRRGDKNDDNNLTRNEKAQETLRQLCRSAIPLVYILVHDVGYVEAQVVDTGYSRTVSTNNPNSKYNQNSNNNQQVRDMRDFPDPDINWLSPNPYANKESGYNRSTQTQYTVQQQSEYNRNRDQQFYQNPNVRLPGYIVEDLKPEHRGDTGDPSDPNYKPPPTGFGGDERFDGFGRNIPIGGGPPNSISNNNNERSIGVSNDWNQRQYPHNYTGSRSGSMNIGQGPNNAIIGPQNSNNYPAYGPNLPPNSDNTQGRYPPGSDVNTRSNWNNIPGYPSVGPGSNFPGISNDNYYPNGTRRDLYASSNYYPNGTRRDPNYPGGNYNNYNPSYPGSAGGSSGSNPYYPGGTVNQQQPYNPRPYDTQHTTWRSNSYPGVPAGVGGGGSYDSRYNTNNRYPVGPGNYPGRVTFNPGDPYVNIWNEQWSTTTYRPTAPGVLGKWRPDLQGQQRPEDINQVPQPVYVTTNYGRIQGFKVKIYDGPWVPLPSRPGIVNVDKAKSVVSSFMGIPYARAPINEGRFRPPRSHPGWQLHQAVEFGPACPQPARFFGFSQGIVQVDEDCLYLNVYSPDVGSGVEGSPFPVIFYIHDGDFIHGASNQFTPHQLVAWYKLVVVTVNFRLGALGFLSTADEYSPGNYGMLDLSMSLKWVHENIRSFNGDPERITLVGLGSGAAAAGLLMVAPRTRAYVKNVVALEGAPTADWAAIIDRYRAQNTTQLYSFKMGCWQEYETTSWKLVQCLRSRSWQELANLELDPDVGTFPWAPVVDRTFKTPKDDFLHDWKEEDWRFLPDSPHSLLRHGDYPFVKYMTGFSRQSAADLLYNNKTLAPNYIVTRDWFDEQIHLWVKKYNYTLNPEGVFSAIRYAYTYYPDPFNVTHLREEYINFLSDALYRSPVDQTVKLLLARGIPVHSYFLNYTLEALRLPFWREVPRGLEYYLLSGAPFMDPEFYPERLRVERSAWTEGDRNMSNFFMTAVANMAHYGQPTPREVLGIYWESCLPSDLRYLALNGTNNSTMQRNYRQRELTFWTEYMPFVVGRDVPTYPPTTEYWYYYYNQPWEPNEPLQIAFWTVSGICLILIVILVACCLLWRMAKKQRDRIYDDLGLGSEPLGLGTIVGDEISEYAETVKTGDSMDSGVKLTTQHPDGGGSMGGRRGMQAFYTSQPTIHNNGHHGTGTSGPGPGSIRGDRFPTPIKRAIRDGGRDTPQTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDB7</accession>
    <name>A0A1D2NDB7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03696</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000091">
        <property type="protein sequence ID" value="ODN02986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDB7"/>
    <dbReference type="STRING" id="48709.A0A1D2NDB7"/>
    <dbReference type="OMA" id="RIVHHSG"/>
    <dbReference type="OrthoDB" id="10263513at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000166">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN02986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="14897" checksum="162637A260010572" modified="2016-11-30" version="1">MPPKKDTKGGSKAPAKAPKKKEGGSGGGKAKKKKWSKGKVRDKLNNLILFDKATHDKLIKEVPSYKLITPSVVSERLKVRGSLARKALEDLLAKGLIRCVVKHHAQLIYTRTTKADDAAAEDEAAAAATEKEKGGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDJ9</accession>
    <name>A0A1D2NDJ9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleolar protein 58</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Nucleolar protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03361</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) complexes that function in methylation of multiple sites on ribosomal RNAs (rRNAs) and messenger RNAs (mRNAs).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles; the core proteins SNU13, NOP56, NOP58 and FBL or FBLL1 assemble stepwise onto the snoRNA. Interacts with NOLC1/Nopp140. Interacts with NOPCHAP1, NUFIP1, RUVBL1 and RUVBL2; NOPCHAP1 bridges the association of NOP58 with RUVBL1:RUVBL2 and NUFIP1. Interacts with PIH1D1. Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000077">
        <property type="protein sequence ID" value="ODN03329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDJ9"/>
    <dbReference type="STRING" id="48709.A0A1D2NDJ9"/>
    <dbReference type="OMA" id="MGMRSNW"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000004">
        <property type="entry name" value="Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000001">
        <property type="entry name" value="Probable Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="283"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="428"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00063404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00082313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN03329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="533" mass="59773" checksum="8FF829F8CFB4CF26" modified="2016-11-30" version="1">MLVLFETAAGYAVFKLLDDSKLEASENLYKDFQSADKASKVVKLKHFEKFTDTTDALGAATAAVEGKVAKPLKKLLKKLVAKDVQEQLLVADAKLGNSIKEKLNISCVSNTNVLELMRCIRSQADSLIGSLPQREMAAMALGLAHSLGRYKLKFSPDKVDTMIVQAVSLLDDLDKELNNYMMRCREWYGWHFPELSKIIQDNITYIKVVKHMGMRGNCGVTDFSDILPEDLEEKVKEAAEISMGTEISDEDIENIHFLAEQVIEISDYRQQLYEYLKNRMMAIAPNLTVLVGELVGARLIAHAGTLINLAKHPASTVQILGAEKALFRALKTKKDTPKYGLIYHAHLVSQASTKIKGKASRMLAAKTALAARVDALGDEANSSMGIEHRAYLEARLKQLEQGDLKRISGGKKSFQPQKYDNKSEVRQYLASGDSTIKERKRKGDDNGDAEDVKPEIKTEPEEEDEPPKKKKKKNKKNKDEEEEVPEPEVEPEESPKKKKKKKQAQEEVEEPAAEEEEAEEESPKKKKKKKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE05</accession>
    <name>A0A1D2NE05_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">snRNA-activating protein complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03207</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000072">
        <property type="protein sequence ID" value="ODN03483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE05"/>
    <dbReference type="STRING" id="48709.A0A1D2NE05"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="399"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="570"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="570"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="962" mass="111581" checksum="C064FDB14C67A400" modified="2016-11-30" version="1">MEGTPYQPPLLTLDDMLNLSNDDDNWDSNAFNISNFFEPIVSSTRENVQQRKEASSTSHASQYVNPFVSPIKAETVLPGTNEDFQQFHTSCPPDTVRIKQEPFDQSFDESFLNVSDEADPGLYEPSNIQEPTQKTPTHEDFKKIFICDKRRKAAISQLQSLINTLKRYSKTLQSFLDNEGDMILEQHAAQELLGQNAKESSIKLHPFDLAHSVTQAVVSHVGRRSVLSRLPRQRPVIWRSSDLLLLQKSILQSAIARREFFLDCRYSQLLLEMGFDLEDVERLQKAPTRHCELTVLRAVMEEHECLSKIKGSLKKPIQTVIIKDNPQTRIPRVFSLPNPETLVNQKWEKLVEIRRETLISNISEKDIDWLFVIKQMSRATPMSNVEEEICKLTYSHLIDPKFNNAVWRAEEVMKLRSIRERFTGSSWTSIAKRLGTQRTPFSCFVKYKIHCVQSTPQLLVQKQSTLEYYIQRYKGNVAKIDQEMFKVTGHYMKPMTLLVGINRTLSPRTRHGHFSIVEDVLLLLTMECYREHLSETENFDPVAYALPWRYITQWRLRFGRLMTGFYHKMWSLEEDQCLWNLVQEHGPKYKVIQRSFPHKDRKQCRARYVHLERILQSMSLQNYHVMYNSRRKNFDFQKLNPIAEYLEMTIKAKAMGCTRYVREADLEFLRRRRAPSDRELECYLLTFQRGVMCVALDRLLGCLLKIQEKYREFSSEMSIAQYLCRTNRRKFDPKCPASTASALHLSCAKLVPMEQLDIPISKFEEDIYTYYQFFSMGSVKKKTKRNLPSLDLLRKLPSIARLIQPADYRPGEPVFVITGQTPKPDIDAEERKEAEVLEEIQKQTKGGARKGAKKRATKIREDKVRAARMRWQKSKLGNVDEQVTMKENIPSDDHNVLLSVVKNEAESADTTDSFNGSAVRNAAVAMINDHAYILPVENPTDLRNLTLGQLFAKMGQSQVKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE30</accession>
    <name>A0A1D2NE30_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytohesin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE30"/>
    <dbReference type="STRING" id="48709.A0A1D2NE30"/>
    <dbReference type="OMA" id="WFILSNN"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF402">
        <property type="entry name" value="MIP16918P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="3">
        <location>
            <begin position="251"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="456"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="885" mass="98941" checksum="4CBF4EB9E730CB85" modified="2016-11-30" version="1">MSVFATLRRKRDRSKGAPSHGTVLVSEAKAEPKFNSTPNLHKINPSVKLPPTAFRKIKESSAVFYPDESEDTIVEDDDGERYGGFGSRRSSSATETESRGGSGSGKYGKNKGSGSGSLRHFASMISMFGSLKRTKSSRKITYGSTQTFDTEKREGTDFMRDRVHGKSPDPELLSTISTSQPSSESTTCLCEVDNGNGKTNLTSNTEPGVRSSSSSSDDDDSRRNSLMDNINKSSSIVRQDDEHNFDYTNTKTEEELKRTKFIIQGVKKFNMDHKKGIEFLIDHDIVQNTPDDVAKFLKYGEGLSKKAIGNYLGERIDFNEDVLQAFLDLHNFKDLILVQALREFLWSFRLPGEAQKIDRMMEAFAKRYCQSNPGIFTCSDTCYLLSYSVIMLNTLLHNPSVKDKPTLERFVLMNRDVDSGKSLNKAFLVHLYNSILAEPFKIPPEDANDLVLTFFNPDIEGWLWKQGGYKTWKRRWFILSNNCLYYFKFTTDKSPRGIIPLENVNAKEVSSSKSNELFPFILYKKSSSSMPSDVIKTCKTLSNGNTVLSQYHTITVASINQEDRRKWVQSINQNNSNSDFYDVLTLKKRSLEAARQQHTREMRSGTPPVVRTPRVRKSLISQPSTAPNFEYKDKLPPELLVPAGPHKDPNNYFKNNCAVFSSSASISSGSAFEPDSSYGSFSDISRSRSESRILDCSRDGSISSVEHDTGSLGSRGNVGAEERSPRGVFASDRKASSSDSEFISHDVRYDLPKKLSVIEESHNHSDRSSSSSGANVVEEDSNSHPVCIGYRKLSEEIYEGDNASHSTGAYFSDSAKCDNNFQTPYKRNTKCPNPNVDINRPLYLSVTEELSSSKNINKIGNEISDDVLTSTTIRYSRSGSIESDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEJ6</accession>
    <name>A0A1D2NEJ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein toll</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02994</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEJ6"/>
    <dbReference type="STRING" id="48709.A0A1D2NEJ6"/>
    <dbReference type="OrthoDB" id="1421090at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF210">
        <property type="entry name" value="CHAOPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="LRRCT" evidence="4">
        <location>
            <begin position="78"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="288" mass="33255" checksum="0A440ADBFD141D92" modified="2016-11-30" version="1" fragment="single">GNLITKIFTDWTYLPRLSILDLQHNKIKSIHPRDLYFTASNIRVDVRYNEITEVDMDFADVLLETAENKHVAVMLDGNPIHCDCHALAFKKFSMPAYLLQHNDLRCHTPPYLHGQKFRDVTENDLTCTIKDNCPKGCNCIELPSENLIKISCYTTAHIREFGVSLRKLNEEHDPYEFEVNLSGKRLQVLNESLIRDISQQVRYVNLTGNKLTSLEFLDSVAEINNVTKFALANNPFRCDGCKFQQIWWRHYQRINDIRSVTCVPGNGGKPLSFYELVKDTYIVEVPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFK3</accession>
    <name>A0A1D2NFK3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02683</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFK3"/>
    <dbReference type="OMA" id="YESRWCG"/>
    <dbReference type="OrthoDB" id="6381944at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905489" description="CUB domain-containing protein" evidence="4">
        <location>
            <begin position="32"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="85"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="228" mass="25343" checksum="DDE63F5F446741AF" modified="2016-11-30" version="1">MSKLVHAHLNSLRNMRSIVWLIFFVSSMTESIPISNHYCPVPTTSSELGTQKVLDLHDIKGHKVRLQFFYPSEEASRKLLESASQGNSTNKTFHSVETDSEEEAMDIPSPNSDAVTQDVYCQWTFRAGNASQFLSLTFEKLSAPYSDNCVQAFVALQKENGYESRWCGNRRQAHARPMSLLARSSAVVTVYRSGNAPLLPVTGFKVSVRELDVGSLQGAESSLRVLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG28</accession>
    <name>A0A1D2NG28_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TOX high mobility group box family member 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000060">
        <property type="protein sequence ID" value="ODN03916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG28"/>
    <dbReference type="STRING" id="48709.A0A1D2NG28"/>
    <dbReference type="OrthoDB" id="10027956at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051365">
        <property type="entry name" value="TOX_HMG-box_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45781">
        <property type="entry name" value="AGAP000281-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45781:SF1">
        <property type="entry name" value="HMG BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN03916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="214" mass="23310" checksum="F4ECA1ADEA6D491B" modified="2016-11-30" version="1" fragment="single">SHQQPQGQSYYAGGQTGQGAGKKSQQQTQQSPQQNQAPPPQQATGPPQSAQGMPPPQTQAQPQHSPVQQPPQQQSPHQQSHQQMMQQMPGSHHIESNQYGGMRPNPGYMNTMGDGSHSHGMGMPGGMHHMGGHGQMVPSGPVMSHMNSDGHDHSQRQMCVRNGCNNMAITSPEWENEYCSSDCVVTHCRQGFSSSSSYSSQHPQTKYVAAAYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG87</accession>
    <name>A0A1D2NG87_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Titin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_02443</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000050">
        <property type="protein sequence ID" value="ODN04242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NG87"/>
    <dbReference type="OMA" id="NEKECSA"/>
    <dbReference type="OrthoDB" id="2152335at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031430">
        <property type="term" value="C:M band"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000050">
        <property type="entry name" value="Titin isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000056">
        <property type="entry name" value="twitchin isoform X4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050964">
        <property type="entry name" value="Striated_Muscle_Regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817:SF151">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00014">
        <property type="entry name" value="FNTYPEIII"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="547"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="696"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="886"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="1162"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="1266"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="1366"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="1466"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="81"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="109"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN04242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1638" mass="184026" checksum="2BD1745B403AC6D6" modified="2016-11-30" version="1">MLAVEIQEVIEEVEERPLKTASLHEGQVEFEEQSLEIREVQPEESVKEIKPTERRVSVGRQTITESKSVEISEVQEVEVGGELKQPRRASKSKASVAVSPQKSVEISEVQPNVSTGEMSDFTTQPQSADSKLVTSESRTTQVVQVHESTGEFSGKFKPTASGRGQSPNARSRRASEKFEQNVFKTAEESVVKVDQAPEEEITVKPKRKVQTPKPEDEDDVNEVVTLKPKKKVEKPKDDVEAGFTIPKPQEPEDVEGSSRSSEEEGEDVEETVTLKPKKKVEAPKDEEFSEELTIKQERKKSVEVVEETEEFTLRPKSTRIETLEDAEFTLKQEAVSMGEDTVSSDITIKKRIPFKTQDLPTESVTLKQLDQTFEDIEGDYKIKLPGRKQSVQASFEDESVELTLTDAVLPLRRPRAAAPTRLRRPSSQIKSNSYQSEEIDQDLSVKLKSQRQAYQTGLEPVTQVEIGESLELVVVIKKTNIKYEHHWFKDGKEVTQNTLVEDTSTHVRYIRRVSKTTLDESGVHTLVIGSGTSIVSQETKVVVKRKCSFSEKLTDMEVVENETALFTVILSEESSEVTWHKDGEPLKQSERIKFIKDEKLRQLVIKSVSVHDEGEYTVVILDNEKECSAEMNVVELPPELKKKLQDTEVPRGDRAYFDIELTKGDALCTEDQGVYACRIGVEEQYSGQGTLTVTEPTVYFKRKLPEFTSAEEERDIELTVEVSDETCAVTWIRNNSITVKSADRYKLVKKGTKRILRISKINKSEDHEFKCVIQSTTSETRTQIQFTTVQVSPKVLNRGELSSLIQVKQHENLDIRVEFSPGNPTAETKWIVQDSQLDFKINERDDGVSEISVYSVQNDSNLEFRAWNSCGEDKVNVAINVSPPSRPGRPQCLDKSDNSISLSWSAPESDGRDAIRNYILESRRSDSSSWSVVNSDFNIEETVFNVYGVEKSSQYVYRVTAENGVGRSPPSEESEVFTIQKSASSKLEFVEELQDVVIGGGLALRQVRGSCTFENRVAKCTLTIDEDSEASYTCVVSNKQSKISSKCRVSCRERVTLTVEEHESVEEISESSYKTRVSLGGEMNLRIRYSGYPAPDIRITRNQQEYEHAVVERKSVVIRKTVEKSDAGNYVIIARNEFSEQSVKISVTVIDESVKKPERPGPPEGPFAVLPNDREELNETLKLEWNPPLQDGGAEISKYSIEQKVQGSWSKVADVNSSMTSYCVQSVQKGFEYMFRVTAENAVGRSDPLLSVPVEIDSLKKLRLPPPLPPFDISGMTSTSFTLRWTESKKPYDVVGYLVEKREAGKKAWQKCATTETNMLDITGLKTNVSYHFRICSLSAANDCSEFVLIQDEAITIGKRITPPSPPQNLMVVAVTSRSVTIQWSPPKSTGGGELTGYIIEKKLEESSTWEKVVTLETSVTQYQISNLREKSVYVFRVFAENGVGVSQPCVSNKVVLKTHATPPSPPTAPLESRQIGVSTMIIEWGIPESDGGAPIEGYVIAIRDSKKTMWMEVGQVGADIQKLTVRELQDGHEYMLRIFARNEIGLSEALESDELIKICNAKLDPSALAEARGGLAQDDEVTTEKETPSLSLTTETHSSWMREAGMDADIRFYSRSALLRRNEYFFRIWHYAKELFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH05</accession>
    <name>A0A1D2NH05_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inactive pancreatic lipase-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02143</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000041">
        <property type="protein sequence ID" value="ODN04554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH05"/>
    <dbReference type="STRING" id="48709.A0A1D2NH05"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF173">
        <property type="entry name" value="LIPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905558" evidence="6">
        <location>
            <begin position="25"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase" evidence="7">
        <location>
            <begin position="271"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="512" mass="56977" checksum="4154973238E0721E" modified="2016-11-30" version="1">MTYKGILFLCVVGLLGISASLVKGVNGDGAKEDPNDDLLMSGAGESQELPPLEPIPSLSSLLPTLVKGKPRKLKDILFRKAPIFEEMLRRKEKRVLEVADKTFTLQFASLPVKKLTSDVDETSSEEVLETRAFEMLSGIVARLVKDVLICSATESEDSVTFNKSSICSNLDLVGHTRMRANEDDSPTECDGSDEDCEVQGRSGVKRPRLTGIPGKSLDYKIYIHSTHRPSHTQPLPTNGKLEGIKIWDKEAPTKLILNLFPYEFCKKENNARNVTHQMIYAFDQRYGHGSENHNIIEVRWPEIWKKKLSIVSVVARLLPTADRLAKLFTKWHKKDQIVLDTLHIIGFSVGAHLAGIFAQNVKKRTSGEAVCRITGLDPIGWGFDMQDEGHQIDHNLSLTPDDAKLVDVIHTSTPDTAYPFIHYGTNQNRGSVDFYPNNGRAKYCTPTDGLCHHFYSTTLFAASIYEATFPACLCPSWEEFITRKCEPCTDVAKMGEQIGAGVAHGMYYLSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI99</accession>
    <name>A0A1D2NI99_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Xanthine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_01699</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="17">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="17">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI99"/>
    <dbReference type="STRING" id="48709.A0A1D2NI99"/>
    <dbReference type="OMA" id="IPGPNYV"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000002">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000012">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908:SF132">
        <property type="entry name" value="ALDEHYDE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8 16" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 17" id="KW-0408">Iron</keyword>
    <keyword evidence="11 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 17" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="18">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="19">
        <location>
            <begin position="203"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="1208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="726"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="757"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="869"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1036"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODN04993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1262" mass="139586" checksum="ADA7C946BAF2D771" modified="2016-11-30" version="1">MGADQSHLPQLENLRTGQSYISFFVNGKEYNVQLDGDPEYSPKYVLVDFLRNKIGLTGTKYMCREGGCGACTVMIKSHHPKTGQEVVRSANSCLLPLYACDGLNITTIEGLGNAKTGYHPIQDRLVKFGGTQCGFCAPGFVINMFAYAQVNPSFTGGNVEYSLDGNICRCTGYRAIIDAFKSLSSTASEELLRKCQDIEDCYKCPLPPLTLTTDSETKDKSFEILTTPRNLYLQNDTSSEEWIKVARRDGPYSTYIDITDVPELHEIAMDKTGMVLGGATTLTTAIDQFMAASKMDGYVYASEFAKHFRRVASLTVRNSATLAGNLMLKHDHREFTSDVFLLFESVGATVRIGSSPTLYQNYTLMEFLDLDMTGKIIMSIHLPTYEQSYIFRCFKIAKRYQNSYADVNAAFLFNIDKGNDFTVSTKPSICYGGINPNFVHAKATEEHLVGKQLKNALQSSLQTLTREAVPNLSPPSTSPEHRLGLAQSILYKFFLGVLRQTVQPRLRTGADDVERGLNIGTQTYDTDKSKWPLYQPIPKLESFPQVSGEAEFINDIQAKFNELFGVFVISNVAKATISRIDTSQAMIFASHKVLYAGQPIGLIVAKNRYAAFQARDKVIVKYENIQKPLLDIKDSVNLQLETNTKVEVDMGFPCRGISSESAKSIMKNMKQNAQQNPNEHHNKVEGSLKTVKGEFITRGQYHFYMETQTCLCAPREDGMDVFSSTQHMDHVQTAIANCLNLPNNSINMNVRRIGGGFGGKLSKASLIASACAVAAFVTHESVRVVLDLETNMKMIGKRLPYLTKYEATVDDTGKIHKLISDMYCDPGAIPNEPSSLFATVVLQSCYRAEQWDLTPHVAVTDTPPNTYCRSPGGAQGVAAIENIMEHVAFEVKKDPLEVRRVNFIQKGDSLVGVPGGKLTTGNPLPGMLAELKKSSDYESRKELVESFNQANRWRKRGLSIVPQRFPVPYADFRLPTFISVYVDGTVSVSHGGIEVGQGINTKVVQVVAYTLNIPIDSVKVKPTNNFVSPNATLTAASVTSELVCHSAQQACFKLLEKMEPIREQLGNPSWQRLVATCNAKGILLTSQCQDLQGDVIAYDVWGLTLAEVEVDVLTGDYRIIRVDIIEDAGNSLSPLIDVGQIEGAFVMGLGWLLTENLAYDEETGELLTNNTWEYKPMLPADIPEDFRITMLKNAPNPFGVLSSKATAEPPLNMAVSVMFAIRSAIDSARKDAGNSDWYRMDAPVSREDIRRLALTSVEQFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIB0</accession>
    <name>A0A1D2NIB0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein FAM177A1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN05018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIB0"/>
    <dbReference type="STRING" id="48709.A0A1D2NIB0"/>
    <dbReference type="OMA" id="HVERYHT"/>
    <dbReference type="OrthoDB" id="45963at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028260">
        <property type="entry name" value="FAM177"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31206">
        <property type="entry name" value="LP10445P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31206:SF1">
        <property type="entry name" value="LP10445P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14774">
        <property type="entry name" value="FAM177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="19767" checksum="DC1D9BA2928746F6" modified="2016-11-30" version="1">MSQVNISESDQGMQLQNMSSSKSAESKESVVKMPTKKVIHFADGSTLEDDDEEDGGFQSSEDKGKSSENPITKSVAHSTDTAAPVDTASMSWREWMRHQGSRAGTKTITVLEGMGGTAAYYLGITTPKYQSEIDEFNRMMTKKKAHDEELISWSSNPQNQAQPVVEDLKKNENGEILKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NID9</accession>
    <name>A0A1D2NID9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NID9"/>
    <dbReference type="OMA" id="VCCAAPC"/>
    <dbReference type="OrthoDB" id="6372047at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41156">
        <property type="entry name" value="AGAP006184-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41156:SF1">
        <property type="entry name" value="ZASP-LIKE MOTIF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="582" mass="62917" checksum="AF25EB0B258AFF93" modified="2016-11-30" version="1">MATVSRTGQLTQAGVTGTGEWDSRLNRLLEDLQETVIPTDTRSRNAAEYREYRLTTSSRVNDEPPQRVDEKWVEVGNLVGGGPVISGSVTDSAYGSSSRFTESKSVAFADETSSLSNRLHTSHRTPQIEYLAPANLTTELKSGPTSPTDYNVVPSGSSRSPKIERKEYFSKASYTTMIKGGSGDTDFPGISTTDSSGPSSSHRLLDDLIPSDFPARGTTTTINPAYESSSSTETRKTYMSSAESQRIGGGLSNGAPSGIGAPLYASTPMKPTSSSTSSYSREVITDRSVTPPPKVVDSLKTPPMIRKILQSSSNDSTSSHRHHHHTTTSSTTATSSSKPPPIGGVPLPILHAGSSASPSVLKPTQIPSYDDPPERLGARYYTSTITTEHRERDVSPIRRFPSPQPPKQTGDPPKRLDDLLASFEDSSYSRSTTLYGGNEGPHKSVPYGPGTHPIQPVRQVRIDDNVTSHGIDESSELIQRKNVTQYQNPAYSKGGKAEPLEPTRNTQGPPVFYPPGQMFTRTEEESMKQEMEKGKGKGKMKAERSYKEKEKMKSKHSEKGGEGAVPVPVCLPVCCAAPCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIU9</accession>
    <name>A0A1D2NIU9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000028">
        <property type="protein sequence ID" value="ODN05190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIU9"/>
    <dbReference type="STRING" id="48709.A0A1D2NIU9"/>
    <dbReference type="OMA" id="ERVMECI"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="72"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="246" mass="28753" checksum="7E7590C0D0CD8D0E" modified="2016-11-30" version="1">MGSITDEENKKIVELRSKVEDLLLDEYTNGDLYLIRWLRARDLNLEAAETMLRNHYKWRAERKIDALLASSPDDYFPKNFPSWLNGIDTKGRPVLCVPMADWDVRLVVEDDRVAEFEDYINRLYERVMECIRKYNEKRKPDEEPITQFTCIVNWDKFSVRQTSNLKAVQTLLGCAAVYEAHYPEILAQAFFLNTNPVFQILFALMKPILAPRTLSKIQCYGSNRSEWEPVVRAAVEEHQIPRQFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJA4</accession>
    <name>A0A1D2NJA4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial ribosome-associated GTPase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01367</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJA4"/>
    <dbReference type="STRING" id="48709.A0A1D2NJA4"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.210.12:FF:000001">
        <property type="entry name" value="GTPase Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008956">
        <property type="entry name" value="PRK12299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF31">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Obg" evidence="7">
        <location>
            <begin position="115"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="273"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="479" mass="52389" checksum="98BA7BADFE6D50F8" modified="2016-11-30" version="1">MFDKISHVDDVDGLLKKKNFGVDDFSPVVSKRRQYFVLSRKRWIIGLSGSDAPKTSKMDAGMGLLLYFHKFSVSSGSSGLILRQLTSCLSKSLCSAQIPQPVLKKKDVGTVNMVGEFVDRRRVTVQGGKGGDGCVAFTKLWANEFAGPDGGDGGNGGHVMFKASFDVKSLALLTPTIKGHPGENGGGSNCHGKNGEHLVVDVPLGTMFKDDETGEVIADLMSPEASVFIAARGGSGGRGNKFFATPGNQSPEIAEFGAEGETIKYIVEMATIAQFGLVGYPNAGKSTLLRAITRARPKVASYPFTTLRPHVGMVFYDDLEQIAVADIPGVIEDAHRNRGLGIQFLRHIQRCVCLLYVIDLSTSNPTPFEILETLKEEIRHYDATMLNRPSMIVANKLDLPEAKANFQDFKSSVGDSMPIIPVSAKFGFNLKDLLIELRKIYDTKQAKEKTVAVEKYEPVRTQQQRKQWRRPPPSTQTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKB7</accession>
    <name>A0A1D2NKB7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">AT-rich interactive domain-containing protein 4B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00969</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKB7"/>
    <dbReference type="STRING" id="48709.A0A1D2NKB7"/>
    <dbReference type="OMA" id="NITLRME"/>
    <dbReference type="OrthoDB" id="10068428at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20104">
        <property type="entry name" value="MBT_PHF20L1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20389">
        <property type="entry name" value="Tudor_ARID4_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20390">
        <property type="entry name" value="Tudor_ARID4_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000009">
        <property type="entry name" value="AT-rich interactive domain-containing protein 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051232">
        <property type="entry name" value="ARID/SWI1_ChromRemod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012603">
        <property type="entry name" value="ARID4A/B_PWWP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964:SF27">
        <property type="entry name" value="HAT-TRICK, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964">
        <property type="entry name" value="RBP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08169">
        <property type="entry name" value="RBB1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="ARID" evidence="10">
        <location>
            <begin position="305"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="117"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="407"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="695"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="407"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="453"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="565"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="594"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="722"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="767"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="777"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="788" mass="87385" checksum="9C9F981DC72EA283" modified="2016-11-30" version="1" fragment="single">ADDPPYLTVGTEVSAKYKGAFCEAKIRKVVRVVKCKVTFKAGNGSSIVPDDQIRGTLRVGANVEAKHPDKNQFLEATINKIQDSSQYTVVFDDGDITTLRRSALCLKSGRHFNESETLDQLPLTHPEHFSNPVVGGRRGVRRRAPNADADKDESSEEEDEYTPTKRDGRRKYERELDMGKVVCVESTDKKKAKDTWFPALVVSPSAQDTVKIRTKDEYLVRSFRDGRYYTVPKKEITEFTKESSSKYDSNSNVLRTAVDKALLYLEKNELPPHWDRDVLFGNARQSESGGEDQQSESEFSEDDPREEKDRFIAQLYKFMDERSTPLNKVPQVCNKDLDLHKLFKTVTSKGGYTKVTNQSQWKTVTIKLGVGTMPSTSTINLVKQAYKKFLFSFEEFYRKLGCTWTPRTTTTSTSKSRSSRSLFRERVTPSSSRESVREPKKDEGSDDSNLPSTKKEVKEKSPPEDKEKTSPTIVAPSPVADSPAAVDTGTGSESEVKKEEESVPRRSRGRKPKKKETEETAAASSSSASPSTAKNKRQTTASKERDSSVASSKDDGGGSAPPTPSSSTTTTTSTTTPTSKNKGVGRGKYKRNSTKAEPEEKEVKEKEKEEKPPAPPPVEPPPPPKSMMDIRLGDKLEVYYPKSEGKTYEAKVIDINEKNESFLVHYNGWNQRYDEWIDRARVSVNITLRMEATGEVDTGKHTNPANPGIHAKGMGKRKGRNSSSATSNSSSTTSSAAVTPTLVASSTASGTRSKVAIAAGKRKRSTSSEIPIISNTPKRRRTRQKSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKJ8</accession>
    <name>A0A1D2NKJ8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="6">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_00950</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKJ8"/>
    <dbReference type="STRING" id="48709.A0A1D2NKJ8"/>
    <dbReference type="OMA" id="WRDEANT"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="10">
        <location>
            <begin position="59"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="11">
        <location>
            <begin position="198"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN05762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="255" mass="28757" checksum="AA1387D46053567F" modified="2016-11-30" version="1">MGSIAAELPTSTKLPSSVSESDADALKYGILEIDLVSKNPMELFKAWYADAHQVPENTYPQAMTLATVRKDGGPSARTVLLRGLDEHGFKMYWDHRSRKTDEIKNDSRGALVFCWTYKDETGTAGGRQVRIEGILEKLTEDDNTDYFNNEPLPAKIRATACHQSRVITDNRDSMLSQIHSLYQKATSGQLELTKPDYWGGFRLVPQMIEFYQGQRDTINDRIRFRKVSETDTPSAADEPGVSVGDDGWVYERLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL46</accession>
    <name>A0A1D2NL46_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00659</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL46"/>
    <dbReference type="STRING" id="48709.A0A1D2NL46"/>
    <dbReference type="OMA" id="ANFAYFW"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042811">
        <property type="term" value="P:pheromone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF44">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="372" mass="42344" checksum="376655E78158F22E" modified="2016-11-30" version="1">MKRVCKSKGSAIQHQDTRYYFTRAGYRTKKASRACSFKSSGGLIMNQKLPTCPGKHHTSPRLQICNFPGNGTDGQGCSGVGMTKCESNSGNPDDDRILLHPFDYIRSLPGKGVRSKLAVAFNYWLNVNPEILSKVCDIMEMLHNASLLIDDIEDGSELRRGQPVAHAIFGVPQTINAANYVYFIALERVLGLNHPKAVEVFTEQLLELHRGQGMEIYWRDNFICPSETQYKETIVKKTGGLFMLGIRLLQLFSDYQSDLQNIVSMLGLYFQIRDDYANLMLAEYCENKSFCEDLTEGKFSFPVIHAIHSHPEDNQIQCILKQRTKNIDLKKYFVSLLDKFGSLKYTETALRQLEQELRDETAVLEETLTSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM82</accession>
    <name>A0A1D2NM82_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM82"/>
    <dbReference type="STRING" id="48709.A0A1D2NM82"/>
    <dbReference type="OMA" id="VRADMEM"/>
    <dbReference type="OrthoDB" id="10255963at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YJBQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615:SF8">
        <property type="entry name" value="UPF0047 PROTEIN C4A8.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="209" mass="23230" checksum="9F4D2A32824AC878" modified="2016-11-30" version="1">MGSSSRGIQMGSAWFQRKINLRPQHRGVHLVTEEILRQIPELGNFTVGLFHIQILHTSASLALNESWDPDVRDDMEMMLNKLVPEVSPFDYSQRTFYAQAQRFNTNLQQGLPYKHSCEGPDDMPAHVKACLLGSSLSIPISEGKLNLGTWQGIWLCEHRNHAGSRKLVVTLNGVLAPGTPISTASSSHSHSHNPHSSSHHSSSHTHHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NNK8</accession>
    <name>A0A1D2NNK8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000001">
        <property type="protein sequence ID" value="ODN06675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NNK8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN06675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="408" mass="47970" checksum="9B37CDF7C9DB003F" modified="2016-11-30" version="1">MESVSDPCAENGKTLHRLGKTRFYVLHDPKNRKYKFTFKEGSKRCRTYGMRLARIEKLTTDAMVSRLLEGLLQKHKWADTWYWIDAQYNTKLNIYTHQDESVPLNGFGTSWDERYCGNSDKRRVLCESENPKCDYKSDNVETFTDSEVNEKYLTEGNFVFSDRRFIVNWKPRTYDEAEAHCRSIGLELHVSQKEDKCLIAYLKLWAQSITMYQFWTPLNYVAGYGFYTKDVDTVELNENEGRSTKLDKNFCVASVYSYEYSNQTACEGKCTWNSFSLAPANCLNPIGTICRHEDYYDRECIWKQAYTDDKMKAVEETAQTFGNRVCGSDKREMINSQWKLPSSFYVTFEYDMQETYWVVDENEFANAGDPNKLCTVATFEKVRSSYRMTTKKVSCTEWHFYLCREKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M176</accession>
    <name>A0A1D2M176_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007578">
        <property type="protein sequence ID" value="ODM86704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M176"/>
    <dbReference type="STRING" id="48709.A0A1D2M176"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="77"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="19518" checksum="C4D916BAC0AA56E9" modified="2016-11-30" version="1" fragment="single">IFSVNTQENCIIASENGVFNGRSERIAPGTPCHPHLSSFQFNDVISSFRLYGGESSLSSAFPNPPPTPNSGSNNNNLGNDFWRLAIHRTAQRYAEYLANSDKFEQSNNDKYGENLAYTSTKSNKEAVVDAVRRWYNEIQLYNYNHHGFNTATGHFTARLESYHTCRNRSGLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2A1</accession>
    <name>A0A1D2M2A1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006202">
        <property type="protein sequence ID" value="ODM87086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2A1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="57" mass="6768" checksum="1BDA51958ECAF940" modified="2016-11-30" version="1">MSEAFDNPWKMEVKDVRLAHYGIWKHLETEDNSKKAYERKVPQLTLTIHTTKTNCSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M357</accession>
    <name>A0A1D2M357_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-phase kinase-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_19310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005466">
        <property type="protein sequence ID" value="ODM87372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M357"/>
    <dbReference type="STRING" id="48709.A0A1D2M357"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="4">
        <location>
            <begin position="3"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="158" mass="17848" checksum="4ED9F5322320AFFC" modified="2016-11-30" version="1" fragment="single">MSTIKLLAQDGEMTEVELEVARISPTIRAMLDNLDEEGVLPLPNISTPILKKVMEWVAHHKDDYPLVENDNEEVAADVLEDAWDTQFLQMDGSRPLLGYRGASKHGYEEDGKYDIRMPRSKGDEGPPQRPKMTSVLRKKQTRAENVVYGTVVIRVTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3F5</accession>
    <name>A0A1D2M3F5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone H3.3 type c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005218">
        <property type="protein sequence ID" value="ODM87474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3F5"/>
    <dbReference type="STRING" id="48709.A0A1D2M3F5"/>
    <dbReference type="OrthoDB" id="4025405at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="2">
        <location>
            <begin position="39"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="107" mass="12035" checksum="6CD517E882A5FFE8" modified="2016-11-30" version="1">MIIINISYYRPGTCGFASNQALSKINGDAPSQSLSRILLVREVVAAFKRQEFRFQVLALEALQEASEAYITGLFEDTNLCAFIQEELQSCRKTFNSPNAFVEMPSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3R7</accession>
    <name>A0A1D2M3R7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004974">
        <property type="protein sequence ID" value="ODM87609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3R7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="216" mass="25310" checksum="13FEBA2428AC96DA" modified="2016-11-30" version="1">MRRFKKPHQTMSRRLSRSRTSLHRLHPRSYTVSNDKVVYIHEPRRDYIEYHDSRILRKRQSERRSCINRLCVGVCNFFNRVKAKERNHKDNSYPPPAICYVPSRSRTLRPRGRTPRTAAHAIDRPLTRMSYDALKGILSYTSQDSLVEMPTWEAMYNANVRAGYEPIIIRTCHSERCAECSSRMITATKEKCGSPNTYRSHEKNILHTVLNGMSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4C5</accession>
    <name>A0A1D2M4C5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor 3B subunit 5</fullName>
            <shortName evidence="2">SF3b5</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004612">
        <property type="protein sequence ID" value="ODM87827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4C5"/>
    <dbReference type="STRING" id="48709.A0A1D2M4C5"/>
    <dbReference type="OMA" id="YDRFNIH"/>
    <dbReference type="OrthoDB" id="10249250at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0747">Spliceosome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="87" mass="9985" checksum="C7AECCEB038F6241" modified="2016-11-30" version="1">MSGAERYNIHSQLEHLQSKYIGTGHADTTKHEWLTNQHRDTFASILGHPDLINFMAICENETKARIRFNLVEKMLQPCGPPPEKPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4X4</accession>
    <name>A0A1D2M4X4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Long-chain-fatty-acid--CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18707</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:54537"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>tetracosanoate + ATP + CoA = tetracosanoyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33639"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:31014"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:65052"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:33640"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004306">
        <property type="protein sequence ID" value="ODM87974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4X4"/>
    <dbReference type="STRING" id="48709.A0A1D2M4X4"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="34"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM87974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="23186" checksum="3BE63D4635D24648" modified="2016-11-30" version="1">MKLLYVLYYKILFQWIKRRRRNETIARCLDNIVAECEGDRICFYFGDEKWTYKQIQALSFRVANHFQEIGLKKGDSVGLAMTNRPEMAAIWIGLGRIGPCLKSEMGNEVTIFAPIFYELERFMEDPKWIPENQDFTHLFPTIDLAACLFKVGPQPTSVAKDQEPNYLDPILYLFTSGTTGIPKLLLVAMDDSVSLRQPHPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M570</accession>
    <name>A0A1D2M570_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein BONZAI 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004059">
        <property type="protein sequence ID" value="ODM88129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M570"/>
    <dbReference type="STRING" id="48709.A0A1D2M570"/>
    <dbReference type="OrthoDB" id="8194173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800:SF5">
        <property type="entry name" value="FER-1-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903489" evidence="1">
        <location>
            <begin position="23"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="147"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="286" mass="32520" checksum="AE893F41C3B252AF" modified="2016-11-30" version="1">MANLQRLYLLVAVCCFLGLTDGTVETSHLRIKVSGRNLKKGILHSDDPYYIVSLSEDGGNTKTEIGRSETISNDLNPDWKFEFELTFDRNNNQYLYFHVYDHDIMKIDDTLGRVWLNVADYVDKGEMAYPNLDKQGYLIITTTKEGQAGSGKLPIPPDAAVAENGTLQFKLSASGLPTKDDILFIKRTGDPYVLVDSVDGPRNTILKKVGRTKTVPDSQHPVWNDVITFNWNRNLDQRIRFTIFDEDLIKHDRFDHVWMEVNDYVAKGQNYTLLLPKKGSITITKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5A5</accession>
    <name>A0A1D2M5A5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004026">
        <property type="protein sequence ID" value="ODM88155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5A5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="292" mass="31282" checksum="1A9BBA4ABB504581" modified="2016-11-30" version="1">MDEEMSNSTMDMTTNSSLNNSNSHLHNHINSSIKDDGPNSNSSSNSHTLHTTHHLGAAANNNNSNNNHQAPWQKFGLTTPSNMMGIDLSNHSGSGALSLSSLHGSGLPLPLSLSAGSPQSVSGSQGSGCGQASKRRKKETPRRIDLPRTAGMPLPAFNSTMGSEMEEDDDAASEDSMAAHERNHVDGLKMDLQHDQTYGDDEECDGQENYEENDPGAQGEDDISSEHGDEMDDDQDGALSLRVSNLSDSERMDRERSRKGNPMKKMLGIGNNNNNNEGGPQNLIHNVSSGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5E7</accession>
    <name>A0A1D2M5E7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty-acid amide hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003984">
        <property type="protein sequence ID" value="ODM88193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5E7"/>
    <dbReference type="STRING" id="48709.A0A1D2M5E7"/>
    <dbReference type="OMA" id="LNMHEGA"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052739">
        <property type="entry name" value="FAAH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372:SF4">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="39"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="465" mass="51345" checksum="5D014F9EF85AF09E" modified="2016-11-30" version="1">MSSAQRSLPSASETQGGRCHSTGWRQETAASQRIRYRRNGLRHTAGSYYRKDIIAAEDAEVVKSLKSVGAIPIGVTNVPELCMWWESHNTVYGRSRNPYDTRHITGGSSGGEAAVQGAAGSAFESGLTLPAPSVCPRYFAEFLVTSLPQALFRWGQQPDVKGRLIELLTTGPMARHAKDLRLIFGVLIGERVHKMNKIPKKAQLRILFMEDDGGSPLASPVDPEMKDALRKAVQHLEQTYGVKAQVSACNGLRTANLYWFFINCQVVLAVLKPTFQNCTQAWKFGVQAVSGAGGVPFCEELSLQKGKINPFWELVKFCFRISAHTLPAIMLGIIEKIAYVGNHLLRHKKLIEMGYSLAKEIQDVLKDDAVLLYPSFPSPAPRHYVPLFRPADFSYCAVFNVFGVPVTQVHSSRFQGFASGSTNCGGMHSDHITISVAEELERDGQPSIASEAWRPLGLWQRNPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5F0</accession>
    <name>A0A1D2M5F0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003966">
        <property type="protein sequence ID" value="ODM88209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5F0"/>
    <dbReference type="OrthoDB" id="8284057at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="19210" checksum="EF0979E59E6DD6EA" modified="2016-11-30" version="1" fragment="single">MPAVHKAAEANKLDESASAEYLQPAGITQEHLFRKELMNAQIDDISTEKREESYEEMASRLKCDNPWFWNTPKCTWIDIKSKNVIERTKRNAKKAAWICGSLFAFAVCHIVYWYKMRNRKNLDKLREKYSPGRIELANGKVGSYQPTAEEYEAYEELIKAIIVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5J9</accession>
    <name>A0A1D2M5J9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Neutrophil collagenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_18433</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="9">Can bind about 5 Ca(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M10A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003893">
        <property type="protein sequence ID" value="ODM88248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5J9"/>
    <dbReference type="STRING" id="48709.A0A1D2M5J9"/>
    <dbReference type="OrthoDB" id="406838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030574">
        <property type="term" value="P:collagen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04278">
        <property type="entry name" value="ZnMc_MMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000068">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033739">
        <property type="entry name" value="M10A_MMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201">
        <property type="entry name" value="MATRIX METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201:SF291">
        <property type="entry name" value="MATRIX METALLOPROTEINASE 1, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="12">
        <location>
            <begin position="86"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="12">
        <location>
            <begin position="478"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="636"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="673"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="691"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="714"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="595"/>
        </location>
    </feature>
    <feature type="binding site" description="in inhibited form" evidence="9">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="535"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="553"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="561"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="573"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="598"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="604"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM88248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="748" mass="84455" checksum="23F0FB4C4A435B20" modified="2016-11-30" version="1" fragment="single">MLLEGKTARNWNTNIVSKNFLQFTSVLHIILLILLIDNGSSFNKIYFTGALNGTVKADDGGQPTLSFCGLIDNLNNTHRMKRFAVYGSKWEHKRLSYRISKYPSSVEDLFVRERINENIAKAFSLWETVTDLSLSRKESGNVDIDISFEKGDHGDGYPFDGPGSILSHAFYPRVNGSSVHFDDDDEWNFGLNEENNFLKVAGHEFGHVLGLSHSAVEGSIMYPWYNSNFTLHEDDIQGIQQRALKELPASKMFITIQFHKWWTEFKIPQNCCKFTGTKKKVPLFIPILLVLVLWVDVGNAATISRTTDTEELVSNESKELFSAIISSLRKFLAAPGLLLFEFTVKLIMFFEKCTFLFLAFVTCLQSNYWNGAANAIPVPNSVGRSNLQNQVLNALSSRNFTSNDALTYLRKFGWLTPDQWRNGTQPVGNFKRLFREFQTFQGIPATGELDKNTIEVMEAPRCGVADRNVNGSINFELLGTKWEFRNLTYTISKYPKNPRLLGGRQNIDAEIRRAFEVWEQVVDFTFTKRDSGRTDINIRFESREHGQREEPFDGPGRVLAHAFRPPVGMVHFDEEERWTMGSAQGTNFFQVAAHEFGHALGLGHSDVRSALMFPSYRGYEANFQLDNDDIQGIQTLYGSSRRPTSPPRGGSTGRVPTRINPRDNQPQPPRITPTGNRPSRPTTMRPRVLTPRQNRTSGSAPTGGMRPPSMTPMGRNSPQLTPNRNPLPTIPTETRSRQRPANRGSSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5M8</accession>
    <name>A0A1D2M5M8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003824">
        <property type="protein sequence ID" value="ODM88287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5M8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="204" mass="22735" checksum="3E99526E2B45AE70" modified="2016-11-30" version="1">MGSVYALESTPNCTNLPTDYRGSIRTTGCIAVYQRTDCSGRSFVVRSDKIELRELTNLTIMPTGPGARLDLEWDLYRDSEKMELETHGGITCECIWLTWRNYAGFFANTHGSCFKVYNNADCKGNPVSEVNGHSEDIPDGGEDGGSMQLCNMPPHCLSSFTATVLNMKLIESHPKLFQATTPKPKMFVNNGNNETEEFITQRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6A9</accession>
    <name>A0A1D2M6A9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RE1-silencing transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003587">
        <property type="protein sequence ID" value="ODM88454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6A9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="214" mass="24103" checksum="88251F8A403C7B82" modified="2016-11-30" version="1">MGGDVQGQSFIRDEIKLEEEEGFVKFECAAFVETPVETILKSDVDVRNEEQSLMGRDVFPGVDADLKLSMKQEDGADEFITGDLDQSDDDDEKEDDVNSPPPKRSRLAVNQKKKGDSSFERKISFNCENCPFSTKNSTHFEHHLALHKMGSNSIVCSECGWYVKPSTMVTHQITRHAASMRPTVNGTEMMTMDNSNLNFVSYYCAISSKRIHKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6B1</accession>
    <name>A0A1D2M6B1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosine-protein kinase Fer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003472">
        <property type="protein sequence ID" value="ODM88517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6B1"/>
    <dbReference type="STRING" id="48709.A0A1D2M6B1"/>
    <dbReference type="OrthoDB" id="3256376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF600">
        <property type="entry name" value="PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="157"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="456" mass="52830" checksum="1820068FE0FDDF67" modified="2016-11-30" version="1">MILYAIRAFGPTHSVILTILDIVVILRSNTMQTTYLRAHIYYTLVTHPILVLIIFTWFYCKLENLTKQILVQSYLFYHYIQDIAFDKNLKNGYRDLLDDEIKKFEDGDLLSDFGITEEFCLEQIHHYRYKKEEYEISFENLDFGLFMGVKTPICFTLADAVLIGSGQYGSVFKLNLNQTDKDGKVTKTVVAVKTIDPKLSDVHCFLALLKEAKLMTYMESTNILWIQLGFVPTKFVKGSSITWKEKHKIGLNTNHLIRWCYEIASGMEFLESKKIVHSDLAARNVLLAADRTVKITDFGLSRRLYNYSIYVKKQKSLNVNTLIWFQTLKINAGSVPWKWLAVEALVDLNFSSKSDVWSYGVTSWEIFELGKPPWPDYKVFSAEFVDDVKNGARMGKPTFCNEEILPVLRLFDELCLAWEETFIFKRSALLFRVVKFRLLLLMDSLQLQTALDGRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6Y6</accession>
    <name>A0A1D2M6Y6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003322">
        <property type="protein sequence ID" value="ODM88682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6Y6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="12257" checksum="81E852D8D138DE57" modified="2016-11-30" version="1">MEATTYCHSAGLQLATIQTENEALFLKLSYDHDYFISLYWTAARDSQKPRALSWDNTGTEPETLTSIRWRNTVREYQICAAFSSWPTPGQYRVMLPCSAPIGTLCQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M837</accession>
    <name>A0A1D2M837_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Somatostatin receptor type 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_17596</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002923">
        <property type="protein sequence ID" value="ODM89091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M837"/>
    <dbReference type="STRING" id="48709.A0A1D2M837"/>
    <dbReference type="OrthoDB" id="6076970at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24229:SF40">
        <property type="entry name" value="ALLATOSTATIN C RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24229">
        <property type="entry name" value="NEUROPEPTIDES RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM89091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="243" mass="27394" checksum="45C7AA8F9D3B28BF" modified="2016-11-30" version="1">MNLSVANVCMLISIIIFIATEHLGNWPFGNLLLIAGKWSKPLIAKYLAGVLWIVSFPLMVPVIMYADTLDIGENIQYCTVDWPDSSTMKGNTQYILYLVMNGFGVPFPFILALCILIVRRCVRDGGQSMNSLQKEKLETTTLVLAIQIMHFACVIPMSAVEFAFIFIRELEFTHSQTYFVILRLSYYLGYSSAVFFPILCALLSTNFKKSFKEACSCAKTQVEMCPEQNMAELQLIPVTETCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8N1</accession>
    <name>A0A1D2M8N1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002715">
        <property type="protein sequence ID" value="ODM89330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8N1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13173" checksum="D97CBBBB84D185A0" modified="2016-11-30" version="1">MGISHMDVQHAGVGVDIDELLKEAVKMNVKDKSSLKILNAEGKRVRGGGNGIKSRSKRATAVKRKRRRVKQQSSEDEELCGEEDESVQKDSAFEKQLQIRVIRLTDEQISEYKMNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8Y8</accession>
    <name>A0A1D2M8Y8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002675">
        <property type="protein sequence ID" value="ODM89392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8Y8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="19541" checksum="3DD6B32BC0D79023" modified="2016-11-30" version="1">MKSSFVYDLKSSSFSCWLNLSCEFNQTELTMDRGQASTFYNPGAGTGPRDGGGVYQNFTAPSTTFINIFSQPGTYNVSLSFAGAAGRENPATGLHGGLINRQVPMTAGAQANGAGGIPMMNRPINPGEQELQNNLSPYLGSPIKGRGGPTMIPEFFGTPEGQKLPKPVPPPKPVKRLAVGTQTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9J2</accession>
    <name>A0A1D2M9J2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Selenoprotein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_17082</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the selenoprotein M/F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002512">
        <property type="protein sequence ID" value="ODM89601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9J2"/>
    <dbReference type="STRING" id="48709.A0A1D2M9J2"/>
    <dbReference type="OMA" id="IKPHCKQ"/>
    <dbReference type="OrthoDB" id="1910009at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.50">
        <property type="entry name" value="Sep15/SelM thioredoxin-like domain, active-site redox motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038219">
        <property type="entry name" value="Sep15/SelM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039992">
        <property type="entry name" value="Sep15_SelM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014912">
        <property type="entry name" value="Sep15_SelM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13077">
        <property type="entry name" value="SELENOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13077:SF6">
        <property type="entry name" value="SELENOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08806">
        <property type="entry name" value="Sep15_SelM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903669" description="Selenoprotein F" evidence="8">
        <location>
            <begin position="25"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Selenoprotein F/M" evidence="9">
        <location>
            <begin position="86"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="162" mass="18227" checksum="D4B8AD780CE0E534" modified="2016-11-30" version="1">MEGLATSAFLSLSVLYLMISYVRSELSVEDCLALGYNRATLVCSSCDLLEKFELTSLKTDCLQCCKAEDPGPVENPVKKYPKARLEVQAFVKSDRPGKFPNLQVKYMGGQMPQIRLIDADGNEETLSITKWDTDTIVEFLQTHLESPPEPERDDENRSDNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9K8</accession>
    <name>A0A1D2M9K8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_17022</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002472">
        <property type="protein sequence ID" value="ODM89660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9K8"/>
    <dbReference type="STRING" id="48709.A0A1D2M9K8"/>
    <dbReference type="OMA" id="KELWVHQ"/>
    <dbReference type="OrthoDB" id="1095242at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001289">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM89660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="340" mass="40187" checksum="2EA72AB5988A4E13" modified="2016-11-30" version="1">MEHKLPQNSKVPMDATTRKNLTSKGKHSCNVCSKTFKTKTLLKQHMLAHQTNRPFQCENCEKAFKSKRCLQSHFGKVHAGESIYKCSKCPASFSSKHQFSQHTWTVHKADMGGVNNECPICHSKFTKTEYLKKHIGTHSTEKSFSCSICLKVFREKRVLKQHMVLHDTKRKYVFCSQCPDKFVAQHVLNRHINTVHLKLKPFNCEMCEEKFTTQGNLATHTTSHLLEKPFKCGICGKRFKINDSLKNHTKAHKNNNYQCQHCFKFYKEKLRLKKHLFKYHIQPREKAFRCLFCENSYMWPYELENHVSSHTNERPWFCKVCGKEYAYKQKLKQHLKKHQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAF3</accession>
    <name>A0A1D2MAF3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-mannosidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16773</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002301">
        <property type="protein sequence ID" value="ODM89909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAF3"/>
    <dbReference type="STRING" id="48709.A0A1D2MAF3"/>
    <dbReference type="OMA" id="CLKYDFR"/>
    <dbReference type="OrthoDB" id="10261055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="entry name" value="Glycoside hydrolase family 38, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050843">
        <property type="entry name" value="Glycosyl_Hydrlase_38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607:SF70">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="Families 57/38 glycoside transferase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Glycoside hydrolase family 38 central" evidence="7">
        <location>
            <begin position="442"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM89909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1028" mass="119002" checksum="0852F7E87B43A667" modified="2016-11-30" version="1">MKWIHRYIAVVLLLSCSIVIYGFSVRRSRDGGTLSMATYWRQQLLPQKNGTENVKNPVCPAPDVDTTSTFSQMNFQATWINKHYFWHSEDFDFETRYKTHLREVARNKNIIKVFILPHSHNDPGWRRSYDEYFLAQTRHTLHNMVDKLASLPKMTFIWSEITYLAKWWKTITPKTKQQFIRLLEEGRLEIGTGGWVMPDEGVATLFSLVHELTEGQQWVQNHLNTHPKYSWAIDPFGHSSTYSHLLQNANMDGMVIQRLHYMWKHWLAEHKTEEFQWRPRWDTTGKFDITCLTLPYDLYSFKHACGPEPAVCLKFDFRKIAFEYGENHGKMTPITKTNVKKLAQEIVTQYHKTASLTNHNVVLVPLGDDFRYDRSIEWDQQYSNYMELFSYINSNKDKFRMEIGFGTLRDYFEAANAMSSKRASLSGDFFPYADVYVWGKPSYWTGFYGTRPYWKRFYREVENELRTAEMLFTFANALARQSNRTNYIELLANQYHNLVTARHEFAVFAHHDGVTGTSKYLTMEDYGNRLYSAYIKTISLQFKSMDVIYDVTLKKTLPSISKGFLRERFDLLPSKIPLEVFANDEYVTRVILFNSLGWKRTELVKVLVKDANVKVTDSEGKHIPSQINPVFQFDSLQVQVHISNRTYELVFLASLEPLAFSTFNVRHRSKDDDNVSILATVYCTNCAQPHESRFTIDTLPQFFQTVKPSSILRIQGPVMSQVTSLHSSKYETIQVNTTLFNLSTTSSSSSILVETYVDFTQDYSNKAEVFMRLDSELNSTTTQKTKNGEEEEVSVMFTDQNSFIMEKRVQVPSIGYEGNTYPITNMVYIQDELKKLRLSVLCDRSHGFFTKRGRLETLIERRNTFDDGRGMSEGVLDSKPTVSSYLLLLENLDKNYAGDKSDTFSQYQPSIYGHTASLKLNYPQSTNDSVVNDENPNDMALMNLQYLVDYKSVIGSCKNTSAKEKDQKHHCTTTSVLESISYFSQLDISKIIPTSLTGLADHAEIDSTKSDKNAKCSNSLLHNFKLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-05-03" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB85</accession>
    <name>A0A1D2MB85_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_16414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002075">
        <property type="protein sequence ID" value="ODM90266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB85"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="414" mass="48537" checksum="7860C8E899D2BE32" modified="2016-11-30" version="1">MESVSSTFEGGDHHRTTEKLACVENPMLNSVGLHSLFRWSISRWLIASSDPYYLTEPPFQKYILNNWELRLRRRTNQTKFWKAYGHLVKQLEIRYSTVFSYKAFRRILFDLTPNLEYLFLNENYYGCRRPKQLLQNSDQRSSTFNVQNKLKDLKIALTFEYMDQYQLPFLWTEILEQFPNIKNLTLKSLCFAKPYEKLDDLLMSIKCLRAASSIGNELWKLQKLHILDLQEKPLSVFPLTTLSYLEELCFPLTSLSIDIGSGTTWHDFKRILTMSSNTLQQLVLYSGGESAQDPCLSFPFGVVLNALRELRFAGPFICHNLDFLQFTPHLRKLEICYFQNNDLVSSWKLRESGSQRQLFLKMWERTHFNSLNSVVLTSMEVFLVGDDWVCDHVEAEAITRMMPNLKVFGKRKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBG1</accession>
    <name>A0A1D2MBG1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002048">
        <property type="protein sequence ID" value="ODM90303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBG1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="300" mass="31773" checksum="CEDCE77DC976B93A" modified="2016-11-30" version="1">MVFIAVRNKFTALTMLSSQMSAQETSSMQKLEDFNGAGDAAVKQTKSTKKRTKKKRKAQSVSEIFGSDMGPDTEIVPNGNIDVGGGSASGQLSQQNVSESISTVTLFGRTEVQSPSPPPTTSSRSGSLQRGESYEATTLNSYAAAVSGRKGSGDSLGVGPPSVLCVESTTAFPSIMTNPPLKKSNSTNSLLAIISDQRKEFKDVGVQVSSDIPLSVAESTGKVNDAKLVCRATMTTPKMGSKTKANLAKLCGCDDLLFAPSVVPPVEFHGECFTFENTIATQFAQMGISFFEEEEMSCKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCT5</accession>
    <name>A0A1D2MCT5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001804">
        <property type="protein sequence ID" value="ODM90759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCT5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM90759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="90" mass="10380" checksum="DE3C7F07D9EEEAB4" modified="2016-11-30" version="1">MNDVVSEMKLKEERHTEPVEYDYFSPALMDCWPKIISFITGPQDLQALMNSCGLFYDLVEPRIFAELITPVLLHKKPLSRKGRPTKIPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDI8</accession>
    <name>A0A1D2MDI8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glutaryl-CoA dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_15701</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001713">
        <property type="protein sequence ID" value="ODM90982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDI8"/>
    <dbReference type="STRING" id="48709.A0A1D2MDI8"/>
    <dbReference type="OMA" id="HMMNLES"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046949">
        <property type="term" value="P:fatty-acyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01151">
        <property type="entry name" value="GCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000006">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000008">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052033">
        <property type="entry name" value="Glutaryl-CoA_DH_mitochondrial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807:SF1">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="12">
        <location>
            <begin position="5"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="11">
        <location>
            <begin position="93"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="10">
        <location>
            <begin position="202"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM90982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="350" mass="38916" checksum="C6BF59D115E0419D" modified="2016-11-30" version="1">MQVDKEMFHREIFNEMGELGLLGCTLGYNKDQPPVSSISYGLITREVERVDSSYRSALSVQSSLVMYPIYTFGTEEQKKKYLPKLGTGEFVGAFGLTEPNHGSDPGGMQTKIRKDGDDYILNGSKTWITNSPIADVFVIWAKDDQNVVRGFILERDFKGLSTPKIEGKWSLRASTTGMIVMEDVRVPKSNLLQVQSLKGPFSCLNQARFGIAWGALGAAESCYKTALEYTMDRKQFNRPLAQNQLIQKKLADMLTEITLGLISCWRAGKLKDEGQLTPEMISLLKRNSCGKSLEIARTARDMLGANGVSDEYHVIRHALNLEAVNTYEGTHDIHALILGRAITGGLQAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEB7</accession>
    <name>A0A1D2MEB7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_15335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001586">
        <property type="protein sequence ID" value="ODM91350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEB7"/>
    <dbReference type="STRING" id="48709.A0A1D2MEB7"/>
    <dbReference type="OrthoDB" id="1405595at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF127">
        <property type="entry name" value="BLOODY FINGERS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="257" mass="29420" checksum="3406DBDDABA68848" modified="2016-11-30" version="1">MNKRSFLYHFMPQHLGISPVPESSEARISCPICQKALHTAATKKDLTKHMKAEHEVEGLDPSRVLKCTECSAYFRTQYSLTCHMKAIHKTERSYPCSECDKVFHNCKQLRLHVRKRHQGAKTGLKGNHECPICQEMFELLPQFERHVKSHEYDGQDRAKGTFICEICSVVCTRRDTFRRHMKVKHGPPTHCCETCGKMFGNRDRLNQHIPSHNDGSNPLICHLCGASFRLAATLKVHLRKKHKAKPTPDIKTVPGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEN3</accession>
    <name>A0A1D2MEN3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cortactin-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001550">
        <property type="protein sequence ID" value="ODM91425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEN3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="153" mass="18510" checksum="B988635E8573EEBE" modified="2016-11-30" version="1" fragment="single">EESEENRSFSHCPLIDLGIDKIEERITLFTIDGNNCILAMNHHQERNKIAAERRKLEEDKLQLKREREEFENMKKKAHLEREDHRNKMINFNRAIRRGTEFVAETERRIHEEEQREQALLMREEVLKVELKAKLDRNMLAGQILKRLHEQEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEY7</accession>
    <name>A0A1D2MEY7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prolyl endopeptidase</fullName>
            <ecNumber evidence="4">3.4.21.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Post-proline cleaving enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_15227</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Pro-|-Xaa &gt;&gt; Ala-|-Xaa in oligopeptides.</text>
            <dbReference type="EC" id="3.4.21.26"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.26" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01001543">
        <property type="protein sequence ID" value="ODM91454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="248387at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070012">
        <property type="term" value="F:oligopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.120:FF:000001">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000005">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000275">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051167">
        <property type="entry name" value="Prolyl_oligopep/macrocyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881:SF2">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="14">
        <location>
            <begin position="46"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="13">
        <location>
            <begin position="557"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="14">
        <location>
            <begin position="784"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="13">
        <location>
            <begin position="1246"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="14">
        <location>
            <begin position="1483"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="13">
        <location>
            <begin position="1963"/>
            <end position="2180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM91454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2185" mass="249269" checksum="8F8AFA103465516E" modified="2016-11-30" version="1">MTKGVKLKKLVFLLQLIQTHLTMGYFGVFAITVLSIVVSSVAIDYPFARRDEKIEEEFFGTKVKDPYRWLERPNSNEVAEFVDSQNDLTFNYLTDCPDRQKVRERLTELWRYPKYGKPEKRGSRYFYYAQQSGKEILNVQDDRSSTPRPLLDSEETGAMIFPHLGASGDGEVLVYRELIKRKSGSPRLTGNLRLKNVTSDLLYPDVLENVRYPQIAWTRNNDGFFYFSHRQITDAKDEGDEEPPAPIIYIYYHRLGTQQSQDTLVFNLLDFHKNPINVQLDMEASEDGNYLLLRSRVFNDQPQARRPNSIYLADLAKFESNGYVGKLQLRPIVTSNSNYMKYVTNINNLYYFRSRIDAKNFRLIEIDINNKGDDRERVVVPENPNYILQSVSAVAPNKVVLGYTSDATGSYAELRELGNGTLIRMFPLKFGELLSFSSTVTDPEVVFRSQTLEGLPQLFTLDTSQEKAAMQPLVELPALTDYDGSLYTSTKVSFPSEDEEPREMVIIHRKDITLDGSSYAFLVEREFDIDFYFRLFFSYMKDYNAVIAIPNLQETDGTYTDSALEDFTSSAKYLINNGYTSPSKLISRGTGVFGLFVAAATNRNPELFGAVIPYMVGFDMVRFPTFSNWSVSATPTDKDDFQRLLGVSPIHNIRLPANETVQYPAILVPTPDNEFPVIFAFKYIAELQYRLGRSAKQTNPFLLRVVAEPQESLRNYARYHIDRETDIRCFLGRTSTTKRNVKMDASTSSYEDEETHTTKSIQAAVGNFGAVRDAWGSHAPFHYPDTRRDEDVSDDYLGTKISDPYRWLENPHSEETQTFIEEQNALTDAYLEKSNWRDAIRAKLTELWDYKKTQCPKKFGSRYFYMENSGLQNQAILYVKESLDGEPRVLMEPNELSMDGAAAISDYEVSPNGEYIAYALSDFGSDWSSIYIKNVSSGHNYLEVLNFTKLLTISWTSDSRGFFYQRFPKTKTSKVSGTDSNVNQKQKLYYHRIGTRQDDDVMIVEFPDNPTWIMFCDVSLDGRYLVVYAGDVVAESHTFYMDIGKSGAITRDNPIVNLFPEPGRHVFLGNDDNLFYFRTNFEAPNFKIISFDVEKNEWSNMIEENPSAVIVWAKIVAGDKLVLCYNEHLDTRLEIHKLDDSGELIKTIAFEDNISPYDHYGRRDLPDLFLRVESYLNPGILYRLYFEDDSVESEVYDKIEIPYYDPTSFTSELTTELDGSAPCILYGYGGFGKTSLPYFDVPYILFAQNFDGVVAVANIRGGGEYGQTWWEEGRGLTKPNTVEDFVAAANFLVNNKYTRASKLTAMGASNGGMVVAAAINKRPDLFGGVIADVGVMDLLRFRNFTIGFLWIREYGDVEKEDELHNILRYSPLHNITPPSSNSSPYPAVFVTTADHDDRVVPFHSYKYTAELQHSVGQTMTQTNPLMMRVYQNIGHGFRMPTMKAIEKATDMFCFLENALGYEGIILPLIASFVVVEVVTFKYPEARRNESVIDEYHGKKIADPYRWLEDPDSDETKAFVTAQNNLTVAYLENAPYRKEMRDKLTELWNYPRRGIPKKRGDKYYFFTNSGLQNQWVFMVQDSLEAEPRVFFDPNTLSSDGTVSIKTSSFTKDGSLYAYGLSQSGSDWVTVHIKNVSTGENFPEVLRHTKWPAISWTHDNLGFFYSRYPSEDDSKNETGKETGTIEHEKTYYHKVGTSQDEDVLVLEFPDQPKLSLSTEISDDGEYILVSTYEVINEELVYFAPLKDSLKSGFKEKLQLKPLNTEPASFSYVTNDESLFYIITDLDAPNNKLVRVDLNKPEKKYWSTVIPEADEVLEWADPINKNLLFTSYTKDVKSTLELRHLQNGSLILEFPLDIGSISSTSGKREDKEFFFKLSTYTNAGIIYRIDLTKDDYKPTIFHETKSKIDSSSLTVEQVFYKSKDGTKIPMYILQRKDLVRDGTAPAYLYSYGGFSSSIEPTYSTSYLVFVNNLRGVVAIPSIRGGGEYGKDWWDDGRLLKKQNGFDDFAAAGEYLIENKYTSPSKLIINGASNGGLLVAATVNQRPELFGAAVPEVGVMDMLRFQKFTVGHYWCGEYGCSENKTHFDNLITYSPLQNIRLPKNESVQYPAMLVKTADHDDRVVPLHSFKYIAELQHTIGNSDRQTNPLLIRIEEKAGHGSGTPTTKLIEEIVDEYGFYIRALNITFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFB5</accession>
    <name>A0A1D2MFB5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium channel protein para</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14998</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001451">
        <property type="protein sequence ID" value="ODM91690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFB5"/>
    <dbReference type="STRING" id="48709.A0A1D2MFB5"/>
    <dbReference type="OrthoDB" id="2984333at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0086010">
        <property type="term" value="P:membrane depolarization during action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019228">
        <property type="term" value="P:neuronal action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF288">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN PARA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="96"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="172" mass="19619" checksum="4F96F3E7AD834ED0" modified="2016-11-30" version="1">MGKIKTPGMEPEGRYSSHQLHPGSTGVDRKDVMVLNDIMKDLEPPEDLKVERVAGQVLWKKSFVPISLSDIFCLWDCGFPWSFIKKIIAFVVFDAFTELFITLAIVVNTVFMALDHYGLEENYIMDMTLKSGNKVFTTIFGVECAAKLMAMSPKFYFQVGWNVFDFIIVVFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFP0</accession>
    <name>A0A1D2MFP0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nanos 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14884</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the nanos family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001416">
        <property type="protein sequence ID" value="ODM91795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFP0"/>
    <dbReference type="STRING" id="48709.A0A1D2MFP0"/>
    <dbReference type="OrthoDB" id="10010129at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.30">
        <property type="entry name" value="Nanos, RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008705">
        <property type="entry name" value="Nanos/Xcar2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038129">
        <property type="entry name" value="Nanos_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024161">
        <property type="entry name" value="Znf_nanos-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12887">
        <property type="entry name" value="NANOS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05741">
        <property type="entry name" value="zf-nanos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51522">
        <property type="entry name" value="ZF_NANOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nanos-type" evidence="9">
        <location>
            <begin position="239"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM91795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="35774" checksum="EF88723482A76007" modified="2016-11-30" version="1">MEMASSPTIPIPGSAFASLSHNLQYLCVPPFGFSPPGYPWSWIPVQPQSPPAYYSPPAGQFYGMNSSSPSYQSRSYSIYPPLPETTMSMTVMSGSSMETRGYSYASPIPATTVSMTFMSGTSIETREYSYPQRPGASNRNSNGSYNLNASFENLRMNDTRNGYNASYYAERCCQSAVIGGGGITVAGRREYEFIAGQRNMPASAATFFQRTGSEVAVSGAFGPIGNPRRRTVSNQPRRFCRFCKSNKETKDFYESHVLRDRNGIQCPVLRNYVCPVCNATGDNAHTLAYCPENRDELGRIRIGSGWLPKAKRAIARRVRYYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH01</accession>
    <name>A0A1D2MH01_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger and BTB domain-containing protein 16-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001287">
        <property type="protein sequence ID" value="ODM92245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH01"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="349" mass="39686" checksum="33CD576C80C9C662" modified="2016-11-30" version="1">MTMTSCLFCTSSSPPPAQPSPLVFQGDSVINEQLKAILVLKHILKIPQETLRRFLQQNNGQFNPEIWLNLCSSCADSVHQFLETLKQISRLEKKLNGIETELKLKMQNSKEVASGSPVAEQIRTCVLYGYSIPETSFEVTENPELQLDDDDDNDDQIHSKFLLEPTSPMDIKQEFEVHQESVATFAVDILSSSPPHDHYSSLFLDPDDMDYETPPATSPPQQLNPQRKRRTIKLQDGNYSYSCEQCPYGSTNIHRYRLHLKNHEPGSKAVVCPKCGWYVMRIGAHNGKAHSRTSDKVGGKKVRRFTYYKCAECQALLGRLDDYKEHEILHENGNLHAVWMALSKDMESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI41</accession>
    <name>A0A1D2MI41_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001194">
        <property type="protein sequence ID" value="ODM92591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI41"/>
    <dbReference type="OrthoDB" id="10690206at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904068" evidence="2">
        <location>
            <begin position="23"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="571"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="783" mass="84310" checksum="984BFEFAC995A560" modified="2016-11-30" version="1">MDLRKKIPVVAIAFCFLAGSRAHLLPQALEDVHAFVQAELNQGRSQGGSQLDIDTPPQGGSAFQTTQTYIGTPVVIQKEVFLDGKNGFQKFVDDLNIGASQIILDRTGPTSGGDPELARGLVPPSPIITQQSTLQLQDAAASTQIAQVIPANLVGPSTFVSNAEQATASSQIIQRNQVKNSQRDVPLPQSRPKKMDGWVPLDQEGTRIAKAVGAQLQGDSEPATLLDESVSYKNVGYSPKTSANEVDAATTTVQVDNLVIGTNSHSASKKLTAKYPVYPGSNSAEKPHPKVVIHAQNVIIRDNLPENSPEAANSPAENSTSGNIQQFQAYSKVPQLNNFLRDQLRIAAMNQLLQSQIALQAQEPLPLPPLHPLSDKAFPPSLSPTRNCSGARNGHFPPSLIEPQPSASSMMSFNIPHFVRMSPDARPLASIQSHSKIPFPGGLGAIYRNLLQNSGGGGSSLFDPREPLDHSLLAALSGQRQKSPRFIPPPHFKSARPDYGDGVAYKFTENPETPEDSQDQDKQKPHIPPITIVSAEPSRPPPPPPPPLGGGSLSQISDDLLKQLIIEELDNSNSNPLLPSSNPFYGGRPQPPRGRRPSRPFPYGTNAHPFSFLNGGGPDSDIQESYNSYGSAGPSDTTSTYIFEGDDDISYGGSPGGPPPPSGGDYDSSDSEPGIMPLTKETMMSLGKSLFHQALDFSKNHNPLTFIQRVRKLPPVKFELYKMPVGIPEGMVNTLSGKQRGPPSHAPPSNYGPPPPRSYRPSSYGPPPRNGGKKKHYTRKYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIS9</accession>
    <name>A0A1D2MIS9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fanconi anemia group I protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001169">
        <property type="protein sequence ID" value="ODM92714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIS9"/>
    <dbReference type="STRING" id="48709.A0A1D2MIS9"/>
    <dbReference type="OMA" id="MAFHELT"/>
    <dbReference type="OrthoDB" id="195089at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026171">
        <property type="entry name" value="FANCI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029314">
        <property type="entry name" value="FANCI_S4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21818">
        <property type="entry name" value="BC025462 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21818:SF0">
        <property type="entry name" value="FANCONI ANEMIA GROUP I PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14678">
        <property type="entry name" value="FANCI_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FANCI solenoid 4" evidence="2">
        <location>
            <begin position="5"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="224" mass="25415" checksum="B85A1CD7F9583694" modified="2016-11-30" version="1">MLQIFNQVLTVASELAISAFPAQLCSTTVLKVVPMIFMVMSGFVEYFMELSKTKADFSIKGFSVPVSRIGKEFKVIVEGMIQHIEQVQRTYAEEETKKNKSKKVPNAVKAQLMKDKKLIPNMVYSIEKYDQQIISLSNKKKDQRGTRLLVGMKLSTARDFKIDAGKLTEALSDRRVVQEMTTVPDEETRMKPDDVPVPAPGSRLRKGRKRKPASKDESHEEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKY8</accession>
    <name>A0A1D2MKY8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="21">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_12991</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 21">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="21"/>
    <dbReference type="EMBL" id="LJIJ01000933">
        <property type="protein sequence ID" value="ODM93687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKY8"/>
    <dbReference type="STRING" id="48709.A0A1D2MKY8"/>
    <dbReference type="OMA" id="WRMFKNI"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000017">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF6">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 20" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15 21" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="117"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="540"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="653"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="20">
        <location>
            <begin position="486"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODM93687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="672" mass="76157" checksum="D7A9B63BA02DFEA4" modified="2016-11-30" version="1">MIRNITGRMTMRNRRVKEKYCLLFILTSFFIVCVGMVFFLPDLRARTSTGVQDVYEKLPDLFLAPPPPPPLENSIDNGSENNVAPRPLNPPPRRVQDRERLYAKIQEDLEKEQRRVIEKPRIIGRPEVSSSANPNRLAQMGSPNKNAESSDVSQRVVGLPSPDGNSPLVNPADSVLAQPRTNSSIGGGKIIYGGKDSDPEVDKKRDFIKHMMKDAWDNYVKYAWGHNELRPISQRGHSASIFGPAKIGATIVDALDTLYIMGLHDEYKQARDWVEHNLDFETIKAELSVFETNIRFVGGFLTAYALTGDTMFKDKAYSLGKKLLPAFDTPTGIPYALISLQSGSSKNYGWAASGSSILSEFGSLHLEFVYLSDVTGDPIFREKVYKIRDVIKQIDKPKGLYFNYVHPRMAKFTQSHVSMGALGDSFYEYLLKSYIQTGDNDARQMYDDAIDAFEKNGLIRYSKSGLLYFAEMRYDRLESKMDHLACFAGGMLALGAHTDPLVINHGSDATRANRHMKIAEGVTNTCHESYIRTATRLGPESFRFSDALEARALRQNEKYYILRPEVIESYFVMWRLTGDPKYRDWAWDAAQAIEKHCKAGEGGGYSGLRNVYSKDPQQDDVQQSFYLAETLKYLYLMFSSKELIDLDYWVFNTEAHPLPIRGKNPFYRAPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLA2</accession>
    <name>A0A1D2MLA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Myosin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000944">
        <property type="protein sequence ID" value="ODM93624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLA2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="36909" checksum="076B2BDB62617A66" modified="2016-11-30" version="1">MENNSSMSSSSSVWDTSLSEIKRKTGGIRESLAEKQKRISELEAQLAVSQHQIQEQAQFIRKQEHLEKELRNQVRERDEEINKLKNKKFWLKIEEEKCEREVENWKEVATRGKAELKAALKAKEGAEERMKKMEEEIVELTQSLMENDEKAIAPAQASSDDDEEEEVNETGRGTDVAVDDSEDGEDEVTTAGRGMNVAIKSSMSSSRNDWWSQPPSSSSSSLVLNKSSVRHAPSKSNSVGSSLSGKGLAQPGRWQMDAGVRKIPPKPKGDVENQYSVRSRGSPKPEQARRIISSSSSDGSESEEEKSQAVTGDVPPVLFPTKRKTKRNSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLN5</accession>
    <name>A0A1D2MLN5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000891">
        <property type="protein sequence ID" value="ODM93903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLN5"/>
    <dbReference type="STRING" id="48709.A0A1D2MLN5"/>
    <dbReference type="OrthoDB" id="5912242at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904228" description="EGF-like domain-containing protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="64707" checksum="5E77C12C8C61560C" modified="2016-11-30" version="1">MKATVLKFKMPYWLLLVILLDFSHKTSSIPVGHDEHSHHHHEEHQDVDHPHVHHEESNHDKEDSFHGDDFDLGFNSEDSEASEEGHTHDNHEESHNHDNQEESHNHDHHEENHNHDSLEEESHFHDNPDHDHQEESHNHDSPDTDHEESHDHHEHHDQDSVDGHSVSNNEFTIKSYKEDCLSANVKCSDGEHLVCDEDLGKCDCPRGMVYHSGKCETAPHPVEENSLENDEEINIELTIDEDDESPTPTPKPNDRDSNKLQGDTHDHDGEEEQDNKQARSGIEILENLCQNVDCEETLGKYSACDENTGECICKDVEQGTRPLRIIDGKCWINRGINDPCKSHEECNATITGNAWCHLDLATRNRFCQCEMYNYFDESLGECLELARDGLFSPCKTDLQCTGSKEVGTGYGPNAECSQESNVCQCKLGPDNQNGFLHMHLCVYEMKMGDACTLDRECEITLPDKDVFCSPATKTCSCREGNQEEDCKKKQNLEGRFLQNDEAESEVNNEGLMNSLKSAIGLDVPNFVFITIIIAVVVLILVILSVFIAKKRHKYSVVKTREQEMEDPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM59</accession>
    <name>A0A1D2MM59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000853">
        <property type="protein sequence ID" value="ODM94140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM59"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="108" mass="12125" checksum="3594A491525344EA" modified="2016-11-30" version="1" fragment="single">NSVNPSQLEPAGEDKNGILYVARTEVNGEWVPGKGYYRGRTFYASVAFMGKEIESADCSVLLRGGTKWIAQQKNREIPTMQFLLVMIQELTKKLTFAEDLPLRKDGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNN4</accession>
    <name>A0A1D2MNN4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O-acyltransferase WSD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000782">
        <property type="protein sequence ID" value="ODM94613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNN4"/>
    <dbReference type="STRING" id="48709.A0A1D2MNN4"/>
    <dbReference type="OMA" id="FGFYCWE"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009721">
        <property type="entry name" value="O-acyltransferase_WSD1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650:SF1">
        <property type="entry name" value="WAX ESTER SYNTHASE_DIACYLGLYCEROL ACYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06974">
        <property type="entry name" value="WS_DGAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-acyltransferase WSD1 C-terminal" evidence="1">
        <location>
            <begin position="281"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="438" mass="49648" checksum="8B8E3B450FF0C188" modified="2016-11-30" version="1">MKSDPQYPGKYTYQKLRSRITEKFGFYCWETLHPMDFCIDDHVRYITNDPSACLTQDQVLREIQKFMDEPLPLDQPQWQILVVPKFLYNRDNDYFAHHDILEDDGFGNFDTITVKKPQKGANYFYGNNYYALVWRINHSLMDGISAANCLQHCISDMPAKLSIDPLQKIPVPFALNFVIYLNMFIFGSRSLLRSMLQRDLNCFHGPGLSGPKTLAWSRRINLDSVKTIRRRNETTMTAVLASSVGSALRGLAIRKNNPVPSEIRSGVTCALLKYPNIRPQRFTVAHLKLRLDPESSKDRLQFATKSAKRLVRSGDILKNYGLIRLIGLLPKTAIPFFMDNCEATVIISNIPGPTEEYTIFQGQKLVDVIGWNTIKGTTAIGVCIFSYAGRIRAGVIGDGAVLPSSSDVPSLVEELEKEIVQMAKDADIKEKDVFMQVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPG8</accession>
    <name>A0A1D2MPG8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CUB and sushi domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_11734</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000731">
        <property type="protein sequence ID" value="ODM94947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPG8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251:SF50">
        <property type="entry name" value="ATTRACTIN-LIKE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904353" evidence="3">
        <location>
            <begin position="21"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="39"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM94947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="290" mass="32821" checksum="D83E255F729B7580" modified="2016-11-30" version="1">MEARVAICLIAVAIFGQTQAATVKHNKAASARFVNTTSCGGLITAEEGLIEYKLDANYGKDERCIWTIRTPLRTGINFTMNRMGFEAPLDGVKLWSISKYGISRAHYFSDWTDTPEDAYVDSTVAIVTFHSIFSIQGQGFSLSFKATPDTDYNLKYYQDYNKKISGDEVVSFRYPENAPYRNLELSTFIVSRHTEDQGQIEFNLTSLELDYEPFVGECHDVIHAYYYRSGISYNDLSRITPLEGVCHTSQVEPPIYHPGYLQKADAIIILLTSDEQNTSEGYEVSYKYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ76</accession>
    <name>A0A1D2MQ76_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">E2 NEDD8-conjugating enzyme</fullName>
            <ecNumber evidence="7">2.3.2.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.34" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ76"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ76"/>
    <dbReference type="OMA" id="NIEVAEH"/>
    <dbReference type="OrthoDB" id="10249039at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061654">
        <property type="term" value="F:NEDD8 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000033">
        <property type="entry name" value="NEDD8-conjugating enzyme UBE2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="11">
        <location>
            <begin position="42"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="8">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM95052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="23823" checksum="47D4DB02AAEC984B" modified="2016-11-30" version="1">MLTLTKKLRREQESRDDQSGGGGRPVISKERLISSSRTTTTLTHGGLLNESLFVQELNSALPSSCELKFDDPDKLHDFHLTITPDEGYWRNGQFVFHVLVTEEYNFAPPIVKCKTRLWHPNINEEGSVCLSLLRQSSIDEMGWAPTRRLKDVVWGLNSLFTDLLNFDDPLNLEASEMYQKDAHAFQQRVNEYIQKYSNKKGSSSSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ91</accession>
    <name>A0A1D2MQ91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ subfamily C member 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000726">
        <property type="protein sequence ID" value="ODM94984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ91"/>
    <dbReference type="OMA" id="IVKITHA"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="333"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="381" mass="43184" checksum="9D17B7DD0AC52ADD" modified="2016-11-30" version="1">MLAKRNSIGKLFPIILTLLAIFIEGNHSEIVILHRLKKTTVFNTSDDIEIRASFSDGKQHGQIVQEKAYLCLSEPLDACAILKSPPSLPSTNYYSSDESSPTDTSIPQVKWVALITSGGGCDLKTKAVFAAQAGYVRVIVKITHAEDVYGFNSLYDDEEIQVDISLLNPSDWDLIQKYVHPKPYVILLPLPNENARPRTASRRLLFLSSTFESIYDFVYILLNFPYTVVDGIDYIIFRCLKELVISPLKLDTLRFREAAYAFICFLIPACMILGPFFAVLIYFSEPTQRPRAPQFFDFEDDPSRNRSVSTPNSNVISQYRGALGLRLFEPLVKRNIESAYKRKALKCHPDKNLENQVEATNQFIIITAAREELLKLVEPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ92</accession>
    <name>A0A1D2MQ92_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Flap endonuclease 1</fullName>
            <shortName evidence="15">FEN-1</shortName>
            <ecNumber evidence="15">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Flap structure-specific endonuclease 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Fen1</name>
        <name evidence="19" type="ORF">Ocin01_11633</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
            <location evidence="15">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
            <location evidence="15">Nucleoplasm</location>
        </subcellularLocation>
        <text evidence="15">Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14 15">Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="15"/>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQ92"/>
    <dbReference type="STRING" id="48709.A0A1D2MQ92"/>
    <dbReference type="OMA" id="MGIPWVQ"/>
    <dbReference type="OrthoDB" id="1937206at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09907">
        <property type="entry name" value="H3TH_FEN1-Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09867">
        <property type="entry name" value="PIN_FEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000009">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000003">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00614">
        <property type="entry name" value="Fen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023426">
        <property type="entry name" value="Flap_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 15" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 15 19" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 15" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 15" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 15" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="18">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="17">
        <location>
            <begin position="147"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM95058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="406" mass="45900" checksum="3CFA39404E311B51" modified="2016-11-30" version="1">MGIHGLAKLIGDVAPNATKENEFKNYFGRRIAIDASMSLYQFLIAVRQQDGMQLTTSDGDTTSHLMGFFYRTIRMIDNGIKPVYVFDGKPPEMKSGELEKRTERRNEAQKALEKAQEDGNAEEMDKMQRRLVKVDKTHVAEAKQLLTFMGVPFVEAPCEAEAQCAFLQKTGQVYAVGTEDMDALTFGTKVLLRHLTFSEARKMPIKEFYLETVLEALQFNMDEFIDLCILMGCDYSDSIKGIGPKRALDLMRSHRSIEKILDNIDQSKYVVPDYFPYKQARELFKNPEVDKEVQISWNMPIDEEGLINYMCNEKGFSEDRMRSGVKKLRAARGKSTQGRLDSFFTVTKRANDSPAAGSSKKPKDDKKKPARVVGAVGASSGESEFVGVCDSHDLIRNYLMYCKILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQA5</accession>
    <name>A0A1D2MQA5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc metalloproteinase nas-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000694">
        <property type="protein sequence ID" value="ODM95247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQA5"/>
    <dbReference type="STRING" id="48709.A0A1D2MQA5"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="38"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="15807" checksum="3FE2C7227581C6CB" modified="2016-11-30" version="1">MKFANYITQEEFAAIRGQKIPIGNITLPKYGEGTVPHPARPGFGARLWTNAEVPYTLDPTFSDEQRIQVALAIQAYHDATCIRFIPKEDHHQSWVDILHDPTVCGVAHVCMNTGAQFAKWWELCLGRKPCNELGAHTLYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRZ9</accession>
    <name>A0A1D2MRZ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">La-related protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_11188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000664">
        <property type="protein sequence ID" value="ODM95495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRZ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MRZ9"/>
    <dbReference type="OMA" id="DICKQME"/>
    <dbReference type="OrthoDB" id="439993at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002344">
        <property type="entry name" value="Lupus_La"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF62">
        <property type="entry name" value="LA-RELATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00302">
        <property type="entry name" value="LUPUSLA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="9">
        <location>
            <begin position="72"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="176"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="546"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="549"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="586"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="599" mass="68360" checksum="0F9C2F1ED8C50B0D" modified="2016-11-30" version="1">MPSPADMEAGGSRVPQNGNGHHKPPHHFKSRGASSIPITADDLHPMVVEEGLVHSHDVHEQEEQPKNNGRHRPRKRKLYGDICKQMEFYFSDANIMKNRMMKEVIEQANENSEGFVELSVFLDFTKIQRLNATITHIQKALVTSDKLELSSDREKARRKVAFDPSKTKSEEQVEDCTIYVENIPRDSDHEWVEKIFQAFGPVAYVSLPKFKSGQHKGFGFVEFDDNDSARKCVEAYGEEGACLPNDIDPAELRSIQSFQEEQEQAQSKIKKSPIGQSPSNSESKAMKNASKQKRKAGETLQEDENEPKKKKGKKVVTSTVASSSSSDSEPEAVEGEESKSKKRKRKKNKGKKSEEAKLESESIMLKVLPKKSWRQLRNRYLNLQRSNMSKLKKQLQQQYLRAQHTKNFYHPPGSEEQHCENNGGHQHHHRNIKKFEEDIPVEEPKVYDPILEVKMTEAAESADNFRSKITIELAEQTEDEAMISGFIKFVDYKDNELQAYVRINGEDSFSSRANNLLSRAQEAFKSARFLTAKEAMDYKKTVQAALKQKQKEQPRRSVRGKDRLMKAATKSTHVRFDEGSDEDVDKNETGVDKTMDTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS46</accession>
    <name>A0A1D2MS46_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000655">
        <property type="protein sequence ID" value="ODM95545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS46"/>
    <dbReference type="STRING" id="48709.A0A1D2MS46"/>
    <dbReference type="OMA" id="KIQPTTY"/>
    <dbReference type="OrthoDB" id="6434376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904457" description="Chitin-binding type-2 domain-containing protein" evidence="2">
        <location>
            <begin position="35"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="53"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="795"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="824" mass="93078" checksum="5AED91CE647ED097" modified="2016-11-30" version="1">MLLPRRTHRTCPFLLPCLLGLVTVIFLCGEFVNAQNYSDSPPRFNYNTLPRTSFSCKGKLPGRYYPDPETDCQLFHVCVKMNSRDVQDFKFLCPNGTVFDAEHQVCIDFYQVVCHQQVGTNPLGHIFEIYKLSADKPNRDLDADKLSFVNRDSVQKNTLGDDFQVEEYNNNRLATSQNALNFRPSPEAPPRRTNKQKEDIFFSNKGFVPSTYQSPSTTRRTTTTSTTTTTTTTEAPSSSTPRRPSLETFESYETESFSGFIPTRNSFGRGHDPTPDFDASTEDFTTKDERPFRTQSSTTSRPLVFQNTFRTTLSHVPPTSKPSAQTFQQQPTRFNDQYFTRIPSTTRRPVSKAAQFFRHTTSADDYFTPEFRQPTVNPFVHQSKSTTIRPSVVFQGNSGTLRPSTNTDFQYETTTTTAPTTTTTTTTDFPTTTEYFSRQRQTEDFEARQTTTYNTDFTQSARNSNFFNLNNGNKPRKQEFGGKSQTAPQRQFPPQLSSQYVEEETLRPRNIHGGSNPRNSVGQSPQPVVISSTRPRDNFGFSTVPPPTTAEPFSTPPPTAAAATQEETAQTLAARLTGRQLFQKVTSKATKNPEKYSIFFGRSTQSVNDDRLPSPGPTTVLYYGSPSSTTSRPIRTRSTTSSPQEYENSPSPSQSLFDRRSRSRSRVDLISSTVAPEQPASSPPTRPRGRGVRRRVRPGRRQHGKEFDPQAKYTRRRFESDRVQDKEQSQKNDEIFNAEASVFRGDPTINNFFQGQRKEANSGLKSTEKDEQPQKQRQPVNPYATEQFYGRRVRPNGNNGRVPQIQNDSQSNNSSSPANNIGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS58</accession>
    <name>A0A1D2MS58_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_10941</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000628">
        <property type="protein sequence ID" value="ODM95738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS58"/>
    <dbReference type="STRING" id="48709.A0A1D2MS58"/>
    <dbReference type="OMA" id="IMATTIY"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10324">
        <property type="entry name" value="SLC6sbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="510"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="539"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="24"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="609"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="627"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM95738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="652" mass="72730" checksum="FAFD865E0DFBE958" modified="2016-11-30" version="1">MNLIRIRIETDRDDTHSYRYRRRLHKRHHRDHRDDVSETWSLPSWPELDGERRTAQEKRRRNRRRSRKTAKSIAAGSLGATSGASGVGAASMGSTSQDTEADEDSERQSWSNPCEFLLSMISMSVGLGNFCRFPYICAENGGGTFLIIYLVLMSIVGRPMYFLELAMGQFASQTQVKVWKMCPAWVGVGYGSAVAAFYVMTYYSSIMATTIYYLVHSCQATLPWSECDPSWATQKVCDQVKEAVANGTNQRNVVNLPRIYYELPQWKLTLCLAASWLIILGVLFKGVESSGKVAYFTTFYPFIVIFTLLGYTLTREGALHGMLFFVQPKWESILDPNVWFAAAGQSFFSLNMAFGPIVNYASMNSFHHSIHKDVLVVSIMDTFASLIAGLTVFAVLGTISHDLGKPIEQVVTSGPGLIFVTFSDAISYFPVPQLFSVLFFLMMMTLAIGSCTSWVMALSSIVRENFPKLKLIWLNTGMCILSFLTALIYVTPGGQFLVTLVDNHGGCVNVYILATMEAIGVAWIYGLKVQSLNEISSAHFDSCGWVITAVSILPLPIGAAYVIYKAPGSPKEKLLYAIKPAVDFGPKHPHDRYEWELFKEGKLVLDEFQLDDDSNPMKNDVEAPNENDGNNELGSTDLPQNASEDENQNKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSH7</accession>
    <name>A0A1D2MSH7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000637">
        <property type="protein sequence ID" value="ODM95675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSH7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="226" mass="26837" checksum="C3289FD84E8E304F" modified="2016-11-30" version="1">MVHVTYVCNKFYSIPRKLQRRTNPDKDDDVGVETFYLMGKFYIYQKPASINYKQENIITILWWFHLTTGEGQKDSMELLKLEGKCKVSILLDEKQSRFFCTIRTCRESKMVINDKDALCNRVKYVMPLKKHPKFEVFEADYASKSMARLDQLRKDSPPRELFRIRKHISCYDTYRFRCPIPKTKEHLRINFNLVVPDMEVTNVILNGIDNNAEEDEKEKDNHLVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTQ3</accession>
    <name>A0A1D2MTQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HEAT repeat-containing protein 5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEATR5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000584">
        <property type="protein sequence ID" value="ODM96075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MTQ3"/>
    <dbReference type="OrthoDB" id="192608at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040108">
        <property type="entry name" value="Laa1/Sip1/HEATR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046837">
        <property type="entry name" value="Laa1/Sip1/HEATR5-like_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663">
        <property type="entry name" value="HYPOTHETICAL HEAT DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20210">
        <property type="entry name" value="Laa1_Sip1_HTR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="843"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1334"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1434"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1771"/>
            <end position="1794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="843"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1434"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1773"/>
            <end position="1794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1806" mass="199592" checksum="0644C408E5725379" modified="2016-11-30" version="1">MHAKFLLLNEAALSELPDVQKPIFILEWLRHVETVLSCISRIELKASQKQLVDQLLLQIQAGPGPPIRNLVAQCMATVFSIGDTITLFDTVNKCNDLLKPLKDDSPSIKLAALACLGCMYSRLGRMMGRSYEETVQVCSKTFRNMESQSRIETLTTFEKICGGMDTACSSSHKDMYKIAKVCLTDRVMAVRTSAAKCILQMMQSAPFLYTTELESLTSLCFRALDGADYDGRIAIAKLLESQFRTRNALQLRGKGIMITSSSSSSKNSSAKPVSLEECLSILMTGFLRGATSFSKGKLSRIFWKSVWESSSRWALPGLRRTWNSSQTTFWNSSPTQSRYQPRRRCLLPKMREFHPPPGFRSSPLRKGAVLSIAGIILKQMNSIDFNPENAKECNQETIFNQHLLVCALQELAALFLSLGTSMYHLVYDPSVSLLNGIFSVLIHPWQSTRLSAAWALRCLCVAIPSETHKTFDTLKTSPEAVSGYSAALSSILGGVRSMPLGIPHATGKIVFNTAEELLRTASQSSRLSIQRSAAGWLMIGAIMTLGNSVVKALLPRMLLLWRNSFPKSAKELESEKARGDAFTWQVTLEGRAGALSSIHSFLLHCPQLLTEEIVQRLMVPIESALAMMTNITSTLKTYGPQLKAAAANLRFRLYQTLTLIKPNYFERSYTHMLRFVIWELTLNDNVANTTTSLFTRVCQSNAIFNSLVSDHVSIEDQLQPTGAAGSGAIEHDPCSLYQELAEFFVFFAGLFSSPPFPPRRGRHRLRYRALRPHISTKHRTQLIDHFVECLKVTKYARKEAVLVNIFCGILMAMRCIRRLGNSSTTVSSSGSSTSTTLNTSFTLSGGEISGQSTSLKSGNGSSSSPPPSSLPSPVIRCAAAEVMGRIAQSVADPRFTSETASFCADKLKISRDVSNRTGHSLALGCLHKYLGGMDSSRHQHGSVSILLNVAQDSSSPETQVWALHSLALVADTGGPLFRSYVEPSLRLVMKLVSTAPLLRVGPELQMAGSSKEIDTMKKSFEIGCALLSRPEEHPLVQNEAITCFQRMHLFGGTINYDVVIPVLFRSMSSTNLLLRRSTVDCFRQLSQREAALVSKYFTKQVQSAPEEKQEEYAYYLESGISGALRDAGFGIRSGIRDTVTSIFSAAATQDKGQLQVCISLCKNILTCDSSARLWGWRWWRGGGSLDASTPPDDSQDFGDDDADALKLNDELSSAGSNRAQNSRWRSRTFAAECLLNLETIIEKFASIRDPDFPSVSILEQFQAQVSAALRPAFAVETDPMVTATACRVSSAWICGNSKGKNIRTKPTLPDFNESANTRKTCNFKSLGASFRHRGGKRVERERLPRPKRRTEPLSSCHLSSPLNYRGREVLSSETRRRTCPTLLQGCLATHPPRFCPPMRQPLPSNWRDSTLCWAGNGGVLRLVIEGMRENFNKIAEKDDDKDPAGTEKELNSEEEATGEELQVSLGNKSVVISRFLSPHAKTPDIKLFQVKSTGTAQEKDKLLGETVASLELLLDICSDAVAIGIQPTVLYLTSCIRREPVAQSDACGAVLRCYKKFVGHRLISNPMIRGEMRGKSICWVLSRSLSRMRRPLGEDWGVLYPSINTFQQAYQSGNEQVRLKAVGLIAQVFEKADRSVSTCFIHALAPRILQFLYGEEAKNVGSKGMLEFILESLRAIQIQVQLVGSSAKRVQMLTLIVPVLINFLVEPQLLGMPMTAHRKLLHDVSLRKLMKIGLQYRETSANLIIDEFRALMGQCTEMRVKLETVIKNSKSLSGNNDKNKTSSGNSTSNSSGGSIKLKTDCSNFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU99</accession>
    <name>A0A1D2MU99_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Meiosis arrest female protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000523">
        <property type="protein sequence ID" value="ODM96586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MU99"/>
    <dbReference type="OMA" id="ANSTRME"/>
    <dbReference type="OrthoDB" id="549353at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905762">
        <property type="term" value="F:CCR4-NOT complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08824">
        <property type="entry name" value="LOTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10910">
        <property type="entry name" value="PIN_limkain_b1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024768">
        <property type="entry name" value="Marf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045602">
        <property type="entry name" value="MARF1_LOTUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034189">
        <property type="entry name" value="MARF1_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379">
        <property type="entry name" value="LIMKAIN B LKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379:SF3">
        <property type="entry name" value="MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19687">
        <property type="entry name" value="MARF1_LOTUS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11608">
        <property type="entry name" value="RRM_MARF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH OST-type" evidence="4">
        <location>
            <begin position="963"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="4">
        <location>
            <begin position="1039"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="4">
        <location>
            <begin position="1129"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="4">
        <location>
            <begin position="1354"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="440"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1451"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="440"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="458"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1626" mass="181548" checksum="D6E22F5CA9D0E70B" modified="2016-11-30" version="1">MHSSKKKRRMKIVGKTPEHREDEIPWSIPMPFDPTFLPTSLYKTAFASTLLTSSNVQTLCEPYHSLATKSSSFQPTANSTRMEPIGDSGCASTPVHQPCIGSSREASNSCPNIAVDVVRCSGSSEIPLSIGKPLPPIGVFWDIENCSVPKGRSALVAVQRIRERFFIGHLEAEFLCVCDIRKEAPTVIQELNDAQVSVVHVSGNSKNAADDKLRQAMRRFADISCSNPLNSSWRHPATIVLISGDINFATDLSDLRYRKRLYVILLHNRHAPDALLLCAHEQYEFHSILTDLPFRSGYRDFTENDNLSIPLKGGLNRVDALATDLPLCNNYKTLNLVRNRLRKLSENCGGKVLSIRGQWALIRFPNYEAALRASKRMNGEDVLGNKIRVVCCPPMEFQSAPNYQPQNVHEEFSTENFMMPSSQHQGNFLASTWNPTWKRAADSSHHTSRHGREANKYNASTTAQSNSSSTNETSRDGSPSVSKSHNIPTVPVQPQLANFAQYVPAQGNNITSTDAATNPSSFAFHQYPVECGPNSFRQDCQTPPQVGADMLGTPRLYSTTIGAGDTNTHNQSFTNQHIMPMYSDGYGKPSPVGNGIYISQSVLAPLSVNNASENQSMVSGQGGNYSKYRNSDADSFDLNVTNIDPALGDWKTIRSTLMSAFSEHVNVRGVWVYVANDGTTSAIVRLVNKEEAHYAVAQLHRKKIGNKRIFISFDNGNAVDHETLKKEVASLLQDVPSHTLPLFKFREMFEKRYKRSVSSSDLYRMKDVVHIAESTLNGSGISTPTSGRIISLTSGWQHKDGKGLDLYCKLHPPRKGKTEKPRMGWAEKEAEVLLPNVIIEIKTLSARVHSLLQSHEEGLPLISFLDCYESEFGVFERATGGRGVPLEHLISCVQGAEIVFGDNGMKRVKYLDKKDEQGKNGKAKIFKNCTRFLILQNVILMIYDCTHSILGINGMINQPLMTQLSQFGRELIDLLKTFPKCTLPFAKLIPCYHAHFGRQCRVADYGHFSLTALLQTLPHIVQIMGAAQNRFLTLSHKAQMKRFATDTLRVLKSQGGPKKQIGIEDFPTAFTNVFPQRQFQPEDYGICFFSDLVAELVERSTLVALIKDEDGNAMLAVPKREQTPQEIHKTRIFASEVVELLRHSTRCELEFSKFVPYYHHHFQKQCRVSDYGFGKLAELFDAINDTVMVINSTSEDCAPDDKTIRLTPKEQIKVVGEQICNIIEQRKSNGQKIRIEELVDRFLEVHGFLLRPDLCGAENLEDLVYNKLESFLMVEDGELIAKDRVQIEDLAQKAETILQQAADYTMDMDEFISKMIEKWDVVVNETTIEKDFSHIMLVTPMNELDETRTVSLTPLRIFAHDMSQLLESHGGYLPLSNIENAHLHKYGQPLRPAQLGYPSLLSMLQAIPDVLSLKGRHRTKKTVMLNSAKFNLESGSDESSGNIGKLTPVSGDYWKNRESRPHSTGASSLKHGKRSEWNGTPKRRSAPPPPLFSPLASPVFHQQASEGSLFAYDQPTPLSPPVCLTISTTYGCQKRFLLAPPPMSPPVVWTCHPIFYPSSPPPGGHGNILVPSTYVAPAWSPPPPNCFENMPQTQQTTMLGNEFLFGRQNRLTASFERLTVDTSNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUH2</accession>
    <name>A0A1D2MUH2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-60S ribosomal protein L40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000515">
        <property type="protein sequence ID" value="ODM96656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUH2"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01671">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="172"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="48785" checksum="0267BC1A369C08CB" modified="2016-11-30" version="1">MSKLVSNTQCNTLLVARLLEKGVLSANDTDVLKTLKNNEGEFRQSYELYTILKTRKDAYDILLESLNLTNQTGAAKILSDGISKERRITRVFWRDSGMSIPDQTEAKFNAILRGLNGELFSKVYLQDFSFLPKHWTLRYMNVLLADGTDLTTLLCDAKFPIYVNTNNGSTFIQIFVNTLLDKTFNFKVLDSVSVAYIKSLIFQEQDIPANQMRLIHNGQHLYDHKTLRECNILNNSVIFLVLRLRGGWLSTDFKAGQKDGVGLLARNEWEGYKVGLNLIGESSNKSCPTQEHNKGETIDRVGCGKSLFRFQIRNKIESIVLESFEGHDKYKYFDPAGNPVEYDKMEIHTVAEDWSLNFCIFCEAEEFKTLLKQEKPSQIITGQDEVIVRNPPDIVNTVDYDGISFRGKFLQFCLLIGFLAVVLAAGKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUU6</accession>
    <name>A0A1D2MUU6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000511">
        <property type="protein sequence ID" value="ODM96692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUU6"/>
    <dbReference type="OrthoDB" id="10561859at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25769" checksum="62D382D5C587E76C" modified="2016-11-30" version="1">MACETCCCCCCTSPKGASFFCASLNVFLGMYLSVKWIVVTYLNGLNDEYFEDDRMRILYPLLLVYISIFLVLGCVNFIAVERESVGVLKWSMRAFILLQISMLLTNTLLGFVIPEHDYDPGVHRVWHIKFMVANIVGTSIYFWVVRKFIYSLENGIYVVHKKRKKVLSATRSTTDESGRHLQSRPSAPWSDSVDRLSPGNNNPRREEGPQTIPLKSSPEPQPGTSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVI2</accession>
    <name>A0A1D2MVI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Vitamin D3 receptor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09992</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the nuclear hormone receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000511">
        <property type="protein sequence ID" value="ODM96695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVI2"/>
    <dbReference type="STRING" id="48709.A0A1D2MVI2"/>
    <dbReference type="OrthoDB" id="6352325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004879">
        <property type="term" value="F:nuclear receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07156">
        <property type="entry name" value="NR_DBD_VDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.565.10">
        <property type="entry name" value="Retinoid X Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035500">
        <property type="entry name" value="NHR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000536">
        <property type="entry name" value="Nucl_hrmn_rcpt_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050234">
        <property type="entry name" value="Nuclear_hormone_rcpt_NR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001723">
        <property type="entry name" value="Nuclear_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001628">
        <property type="entry name" value="Znf_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24082">
        <property type="entry name" value="NUCLEAR HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24082:SF482">
        <property type="entry name" value="NUCLEAR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00104">
        <property type="entry name" value="Hormone_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00105">
        <property type="entry name" value="zf-C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00398">
        <property type="entry name" value="STRDHORMONER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00047">
        <property type="entry name" value="STROIDFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00430">
        <property type="entry name" value="HOLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00399">
        <property type="entry name" value="ZnF_C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48508">
        <property type="entry name" value="Nuclear receptor ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51843">
        <property type="entry name" value="NR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00031">
        <property type="entry name" value="NUCLEAR_REC_DBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51030">
        <property type="entry name" value="NUCLEAR_REC_DBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8 10 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nuclear receptor" evidence="12">
        <location>
            <begin position="97"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="NR LBD" evidence="13">
        <location>
            <begin position="250"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="485"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="591"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="686"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="751"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="487"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="598"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="686"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="708"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="762"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM96695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="795" mass="88270" checksum="5297304D3C45E582" modified="2016-11-30" version="1">MDHPAGKSIIRPEPRLAQPQNHYQSALQQQPSGSGSAGGVGVVDRSFLLESSIFRGPGTIGAPSHATSGEFIAPSSSPPSSYGEGKGFSRKRSRKRPKTCGVCGDRAKSFHFGGLSCDSCKAFFRRSVQNDAHVAFRCAYDSCCDINISTRKSCQFCRFKKCLAIGMEKSWVMTEEERNALNQQRLEKKQTKPVATVQQPPVSEPTYTFQGTTKSTSVSREPAALAFLDSEYVADVDKMLDYMTYEEQLEIKSVVETYLHAYKEMPFRVSLAEGRRDTLEIIEMFTTILRRFAYFSKLVPEFADLSRADQGNLLRAAVLEMCLLRGAACFDTEKNRWPSSTMESLKDCPQLRVEDMQRLVSRELFEMHISFIFHMKKLRIDEPIAMLLIMTVLFSPERVSVESRVRINQSQEKYLMLLKKYVSWKFGTTAGSRIYPQLLTKLSDLRQLNDFHTEFHLNLDRNEVNAIKKSLMELHLNPYPNWKIVPESRQSSPEQSRPSSPILPAPSPFVESGPSSLPRATQTLIQSFADRRIPTLLDNPYAVFETDLGLIRQVQQTFALSAYNQSLHQRHPSEDSDGSRMISIQDQLANSETFAPNGGSSSVSPRGHSSSTESTEISALDILHNSRSHEYQPPSLTNTTTSSSCHSEALSALSGEYHVDRLQQFLQHRGQTTGLEPETVLRGHNSSISTTGCPHGSQTQTVLRKHSSGSSLPSTPSSVIRSAHSRPVDPPINADGRLDARSFRSISCSTVSGGGWHGGEVHTTTNGHRTTGSTSTVTVTTATRTQPSSYEGDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVJ6</accession>
    <name>A0A1D2MVJ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000477">
        <property type="protein sequence ID" value="ODM97036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVJ6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="241" mass="28066" checksum="BB47A7F63E0618FC" modified="2016-11-30" version="1">MEEEGKSLESSSRRSSSEYESWSSDESDEEDGKIWLSLFDVMDQLREIGRVCAIEDLPLKIQKKYYGTNESQLKLAKAVPVPPDYLKVETIFDCVITDGYASTANNRANSIFYAIATTMFNEKSPTAIMINQVKLLYLKQLEVDYLTTKSNKNRREFRKCLWQINKTLREPNDPWTENDWLLASKAYFCPIHVLHLCPRIPHNPHVQRYAFSPVVDNEPPLRFVVNNGEYIFKDNKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVP5</accession>
    <name>A0A1D2MVP5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial fission regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000470">
        <property type="protein sequence ID" value="ODM97129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVP5"/>
    <dbReference type="OMA" id="PCRIFIP"/>
    <dbReference type="OrthoDB" id="2133332at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007972">
        <property type="entry name" value="Mtfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14215">
        <property type="entry name" value="PROTEIN OF UNKNOWN FUNCTION DUF729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14215:SF0">
        <property type="entry name" value="WH2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="441" mass="49130" checksum="9B8759C61F82B64B" modified="2016-11-30" version="1">MAFQRNAKNKRVEVFEQPVYDVIHRVEEVRLSPLVEVAIVGGLGVLIISGPAIASFVKRKFQVLTTRLVILKDRLCQAKLAKKLEALNRRRKMGSIVRVVGSLLPNSLFTPPCRIFIPNWAQLKSNQQWQSQPQNNLIGLEFATKLDPPSENLVGDGLIEAFEVASEVISSISGDEDDEETASSSPEGWAQEQREFPTNFNPTLNITDSSFARCSTPKGTRPALHFNATQASQCGSEENLEVSRLRKMVELTTHLLQLGRRHPLLHRRHTTPPMSLEGSRPLLIVKKGNQNQLVDKKPQASLSDVLKELPNAKLRRVERSPGGTPIKPQLKLAPDNLDIRSQLESALRKRFESMHSPMGEAEDKENIDDSEDSFEDNPVSAKRTLFPTARSPAPRRRSSGNQSSSENGTPPFGQHLLKRRNIQASDGEPLPLAVAVLRQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVS7</accession>
    <name>A0A1D2MVS7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">GPI ethanolamine phosphate transferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_09661</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000478">
        <property type="protein sequence ID" value="ODM97018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVS7"/>
    <dbReference type="STRING" id="48709.A0A1D2MVS7"/>
    <dbReference type="OMA" id="HPSFNAW"/>
    <dbReference type="OrthoDB" id="272139at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16023">
        <property type="entry name" value="GPI_EPT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037675">
        <property type="entry name" value="PIG-O_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039524">
        <property type="entry name" value="PIGO/GPI13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071:SF1">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="519"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="554"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="587"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="635"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="662"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="727"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="777"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="810"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="850"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1005"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1029"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM97018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1215" mass="134250" checksum="4388E7FC7789F695" modified="2016-11-30" version="1">MDSHEHHHRRNMSKIQTISVISFLSFSVIVGTLVFSRGFLLNRQIIPDKAGPCLDTAYRQRDQFYHEQGEHLGQQLDGVELLSNLSESASWCNPSPVFKKAVLILVDALRYDFVSRMTFLSSIVTDKDKLKDNNEQHKNHKSVTSSTKNVNGNRDAAAGGSYHEGPGWESSSCLFRFVADPPTTTMQRLKALMTGTMPTFIDASANFNSYEVEEDSLIYQLNAMGKKLAFLGDDTWLSLFPPSYFKSPVVEAHPSFNAWDLDTVDRAVNHSLRNKVFGREAEKEWDVLIAHLLGVDHCGHRYGPSHPEMVRKLREADEIIEFVFNSMSQDTLLVVFGDHGMTPTGDHGGDSKDETDAAVVFLSKAIKQRRNIRGEINSGSLHSASFQCPSYSSSISQIDLVPTLATLLGTPIPYSSIGQLIPNFIGKKGVYSDAVSANVAQVERYLRKFGIVGSISKSSSSGGGHGLEEEYLHLQEAFHSYQLSRTNQSSRAKLNALAHKYLNRVKFIAVSTWTQFNVPMIYCGVAISSLACFSLFVYLNHVRSLLSSRRKHKYSVLSWLWPSLPLWSVCVTFFQDKPSPATNLWNVIVSTLSGLIMFLLALGMKLIQKMGEEEEEASSSADTASSSKRKSGWNFCDLGALSIYMLTCLAMFSNSFVINEGYMLGSALLLVVFLYVLTSPSNLPRRSNNTMAGDQARGSEQHHPLGVVGGKDEWLLVEILCRKSTKCSLVCFVTLAALVRICSIFFRCREELTECTEEYLLHKQLSSLPEDWQVHKYVRYSVALVSLAIFVVAFRLWMLYQKCLFSKRPAAIVAKFIPSLLVVLLGVLWALQGLPLISSSAAKLRPILNYFPWVFQASTFISLVIVWVKPIVSGGGAGQSLLLPSHFQVGCSRCSQASAGKKRAESIGTSSPAAVGNNNAVIWSKPNVNASSNYSSTVHKPTLHKNNSGANGVNKKVNGLQKLCDQISMKNQPKRDQKRVEQLSKSVFLEMEQQKYSLEDSGANGSYSCSILVFATLVIVLMAQITSAGLTPAVAIVIPYSIICLVGIYRSKNLSVSSPTSHLNSDGDSWGGVVAWALCSQYLFYGTGHQPIFSAIPWDSAFLTTTDGTSFTDASGSWLTWVRPALAIIGNLHVSQITFSLALPLLAYWSNETPLNCHHQCHAKRRKAYILCGKYILLHGIKLLACMACAGWHRATSWCGKYLPPSLSLKRSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWJ7</accession>
    <name>A0A1D2MWJ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Piwi-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000464">
        <property type="protein sequence ID" value="ODM97194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWJ7"/>
    <dbReference type="STRING" id="48709.A0A1D2MWJ7"/>
    <dbReference type="OMA" id="HETICNT"/>
    <dbReference type="OrthoDB" id="445936at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034587">
        <property type="term" value="P:piRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02845">
        <property type="entry name" value="PAZ_piwi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04658">
        <property type="entry name" value="Piwi_piwi-like_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="274"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="580" mass="66008" checksum="FFDEEFA29BBA1D8E" modified="2016-11-30" version="1">MALLIKGDPKGKQKFNEFVVNKIVITKYNHVSYRIDDVAWDMTPMTEFERKGQTCTFVDYLKHHHNYVVKDTTQPMLISKLKPRKNDRLTQSDTTQRVAALVPECCHMTGLTEDQRANFKVMTDLAGSTRLTPQQRVEGLHRFIDRLMKCEAAQELLSQWSLEIVPGIIHVEGRKMDGPGLSFGDRVNLPKAGPDFSREAGLSVYDPIAIKRYAVISTQRDSDKAKRFIEMYQQVSKPLGIKMMQLGTLVTLRCFLPHDFNNALRGLDKNSTQFVVIIMPMQRDDVYAAIKKFCVSDCPIPSQCILSKTLGNEKRLRSIVLKIALQINCKLGGSLWALQMPLKEQVMFVGIDAAHDPLKKDPSTVCLVASLNNECTKYYSKAASGRVHQEMAESLRGMLEDAIKYFQSVRHRVPDRIIVFRDGGSVGAMEHIEKTEMEQLMQAQQQLAPDASFTFAVVAKRIPQRFFLDQGRKGFDNLQPGSVVDNTVTRRHYFDFYMVSQQVRQGTVNPTHFIVLNPNDAIKTDLIQKLAYVTSFMYFNWSGTVRVPAMVQYAHKLADLLSRHVKAKPHETICNTLYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXE8</accession>
    <name>A0A1D2MXE8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000422">
        <property type="protein sequence ID" value="ODM97662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXE8"/>
    <dbReference type="STRING" id="48709.A0A1D2MXE8"/>
    <dbReference type="OMA" id="KPLRHNN"/>
    <dbReference type="OrthoDB" id="245697at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="33"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="496" mass="56345" checksum="B484D93114711555" modified="2016-11-30" version="1" fragment="single">ADHGTKGPLDKGSRNFGSPLSSKATAETRLNRLRNKVIQEIVKTEEIYVNQLKIIQNEFMEDSDIKLTFTKREYNAIFSNIPILLEVNERLLKELKTSEFCTSSRSRNDENDIDSLPSIQSVADAFLNYAPYLKLYSTYASGFQQSHEILLKILGQNPQLRSLVKTKEENLNNTLQSYLITPIQRIPRYKLLLQQLISYVSSADREDPTSKAIIDSIKRLDQVAQHMNEMIRQHENSCKLIEISTWIGKNYHGTLVEPGRYFIKSGSVLKVPSSTIQQSLTGNNQFYLILLSDQLLSCKIKSEIGSKGCLQPTLVLPLKKCIASLIDIYAEVACEGEILKFTLMEPDDLQDWVTTINESSRALKTRSATLKKESSNTKPLRKEQIKDIVKRKKRGIKRGRSEESPAPTPGKLRRFMNISERLDQLVDYFSPTKSGLTQRVADINVSSPVCHTPGRMETIPEHSGGWYGENEENEHDLQNLKLMSVSRYPQTTCNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0M2</accession>
    <name>A0A1D2N0M2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial</fullName>
            <shortName evidence="2">Glu-AdT subunit C</shortName>
            <ecNumber evidence="2">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000320">
        <property type="protein sequence ID" value="ODM98819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0M2"/>
    <dbReference type="STRING" id="48709.A0A1D2N0M2"/>
    <dbReference type="OrthoDB" id="5394539at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="GatC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15004">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15004:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="Glu-tRNAGln amidotransferase C subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="176" mass="20053" checksum="6D48CB7CEEC1AD4F" modified="2016-11-30" version="1">MQKRYFSSVIKNFNVRTHVGKQKHYLSTSWTLDTRLESLSSCRWIPRLTNLDSFRNFHSSLLNNSSQDNGGKLSSGEKLSSDLVHHLERTSLVDFDSAEAVTRLTEAVRFADQLFEVNTEGVEPLVTVLENESLYLREDIAEQTNRKDILKNASVTEEDYFVAPPGNIPLEPTSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0U0</accession>
    <name>A0A1D2N0U0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane emp24 domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_07757</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000311">
        <property type="protein sequence ID" value="ODM98917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0U0"/>
    <dbReference type="STRING" id="48709.A0A1D2N0U0"/>
    <dbReference type="OrthoDB" id="3427at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904856" evidence="10">
        <location>
            <begin position="23"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="32"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="28295" checksum="EF388BB752E12164" modified="2016-11-30" version="1">MEMNLLVVVGVLTLFCPAPINSFYFHTNHTVIKCFSEEIPDDTLVIGMFRVEPWHVGLGKFSNDTYGQGLKVNIEDPQWRPVLSKVFGADGRFAFTSHTPGAHRICLSSNTTASDLIFFTTPISVTEDPTRYRNTLQNDEGKEGDLRIHLRLNVGRHAVDYDVVKQKEKLTSVQLRIRKLLDLAEQIVKEQEYQRLREDRFRQTSDSTNSRVFWWSLIQFMILVGMGYWQVSNLRMFFIMKKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0W0</accession>
    <name>A0A1D2N0W0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000343">
        <property type="protein sequence ID" value="ODM98545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0W0"/>
    <dbReference type="STRING" id="48709.A0A1D2N0W0"/>
    <dbReference type="OMA" id="YRTRTEY"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="8">
        <location>
            <begin position="69"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="9">
        <location>
            <begin position="476"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="10">
        <location>
            <begin position="759"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="820" mass="90540" checksum="5115A382214A18B4" modified="2016-11-30" version="1">MAMNLQQMLRRGRAPAESSGPFRGITVTVIATMLASVSVYLRSWAAYDRLSDSVGNTAYSIFSTEKDHFDFIIVGGGTAGAVAAYRLSEYYDVLLLEAGGEMNDFQLIPAMSLLMLNYPEVDWRHKTVPQRHSCWGSPKNRSHWSQGRGLGGTSNLNFLIHARGCPKDYDLWAQLTGDPSWSFDAVLPYFKKSENYIGRWQDNGFHGTRGPMTLIEPDFTGVGETWVQATVEMGWPRSDINGNFTEGFDTTTYTMKDGRRAAAYGAWLDPLRNRLTLTIRKYAHVRKVLIDGQKRAYGIEYERHGQIKHAFAKKEIVLTAGTMNTAQILMLSGVGPRRHLRNMGVPLVKDLPVGLNLQDHLSVYLGPFFVNEPIKFSIGDDVINPSTIGRFIIQGKGALTSAGTQATGFFSTKLAKAAGEGDWPDVQIIVCGVSAGENFPSEIARGFGMKKQLWQDYYEHAIGYHSFFLIVSGARPRARGYVRLKNTDPMSPTRIQPNYFDNQHDVETMVEGIKTAVAIVEETQTFHDIGGRFTDKVLPGCEQYKFRSDKYWECYARTVSVSLHHIVGTATMGAEGSPGAVVDTQLRVVGVTGLRVMDASIMPRVPIGNTNAPTIMIAERGTEMIINLWKGTRLGDPLGVLKRDIPSPLIQDGSGGQGHMEGKLFHPLMDEYPKCFIVGADNVGSKQMQQIRIGLRGTAVVLMGKNTMMRKAIKGHLDNNPALERILPYIRGNVGFVFTSGDLVEVRDKLLENKVRAPAKPGAVAPLDVIIPAQNTGLGPEKTSFFQALAIATKISKGTIEIINDVHILKPMKKLHDSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1P4</accession>
    <name>A0A1D2N1P4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Histone acetyltransferase</fullName>
            <ecNumber evidence="3 14">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_07500</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 14"/>
    <dbReference type="EMBL" id="LJIJ01000295">
        <property type="protein sequence ID" value="ODM99178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1P4"/>
    <dbReference type="STRING" id="48709.A0A1D2N1P4"/>
    <dbReference type="OMA" id="TLEACPM"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036409">
        <property type="term" value="C:histone H3-K14 acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010485">
        <property type="term" value="F:histone H4 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000022">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002515">
        <property type="entry name" value="Znf_C2H2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036060">
        <property type="entry name" value="Znf_C2H2C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF161">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103637">
        <property type="entry name" value="CCHHC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51802">
        <property type="entry name" value="ZF_CCHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="16">
        <location>
            <begin position="704"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="584"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="976"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="122"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="225"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="355"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="987"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="880"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM99178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1013" mass="110797" checksum="D18979976673E96F" modified="2016-11-30" version="1" fragment="single">KKKPKMTKSKAEKKSMVEGTKKKTQSLTKKTVAPASSTDEEEEEASSTTRKSHHPIIASKPTSSSNGISTPKGALQPKKKKKVVSSPVVTPNSTSNNHNKVPKKEKTPSTGTLKPLKGTPVPGKGAPNSSSSGPKKKSQNGNVASTPPSAKKVVSSSSNDGKQGKSAASKNAKANLSTVLKSAPKINGGKVPPKPPKKHPPPAGDVAKKGEKKLEVSSSSTVGVATRRASRSTSCSSSASASASSSSSSSDSSSDSSNESTASKSNNESKKPAESRLSSTSTSTSTSGSGSSSSSSSDEDEESIAAEKTPVVRAPPAPIARKPTTAANRISKRDEKKGVKSRAKKPAESKVIKIRSSSSCSSSAERSSARSTTSSSSARSRSSATIRRTATKPTKTELSISSTENQPADIIQKHWQQIPRVKAKPPASTTFIIPSASDQEMKSAKEDEGEIEAEAEQSTRPVTRRQISKVKKSNKTIPTTTKFSLDKLHEKLESSSSPRVVYNEASDSDYSCGSGGDNQVFIRCVPAKSSTSNMKKILVEDNRICMFPGCDSNGHLSGLYEKHCLISCCPKYHIDSGFFLGRGEEESRTEDADPRSEEELAPRDPSEECQQLCRMRSNRMTARSHYTPASSNPLTLIPTSNHQKLFKNPNKYHPQPQEVKQWVTKMKELKDTKLDSNTSEYDMSLWRDALALAAAQIESEQNSSVQFNKWSLAMGKFEMGCWCCNPYPEPLAQLRRIFICEFCLKPVQSGTVLRRHCAKCVWRHPPGDEIYRKDRLSVWEVDGKTQKTYCQYLCLLAKCFLDHKTLYLDVDPFLFYVMTMADSQGCHIVGYFSKEKNSFLNYNVSCILTLPPYQRQGFGRLLIDFSYLLTRVEGKIGSPEKPLSDLGLISYRSYWKDAVLRRMCACASRDVSIKELSQELGISSADLVSTLQFLGMLKYWKGKHLILKKQDVLEEYLERVRRRGVEQRQIDSSCLRWRPYQPPPDNSQSQEESNSISSILNSVVSGGGGATTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N231</accession>
    <name>A0A1D2N231_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein KRTCAP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KRTCAP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000288">
        <property type="protein sequence ID" value="ODM99300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N231"/>
    <dbReference type="STRING" id="48709.A0A1D2N231"/>
    <dbReference type="OMA" id="ITIYYMN"/>
    <dbReference type="OrthoDB" id="1111004at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018614">
        <property type="entry name" value="KRTCAP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32001">
        <property type="entry name" value="KERATINOCYTE-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32001:SF1">
        <property type="entry name" value="KERATINOCYTE-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09775">
        <property type="entry name" value="Keratin_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="14648" checksum="A4CB7F23D595752D" modified="2016-11-30" version="1">MALSHEMSGIVSLIMSVGVFSGMQFYRHQLASSGPLTILGGGLGSVLFLFILTAVGNIEISLFGKGYQTSLFPEIVPCLVLALIASGRVHGVCITTCFLFSLVTLYYVNRISHKTYGHGAAAATVNPAAQSSHKKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2K7</accession>
    <name>A0A1D2N2K7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">WD repeat-containing protein 35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_07527</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000296">
        <property type="protein sequence ID" value="ODM99145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N2K7"/>
    <dbReference type="OMA" id="CVSETHM"/>
    <dbReference type="OrthoDB" id="10260567at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056158">
        <property type="entry name" value="Beta-prop_IFT121_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056159">
        <property type="entry name" value="Beta-prop_IFT121_TULP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057979">
        <property type="entry name" value="TPR_IFT121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056170">
        <property type="entry name" value="Znf_IFT121-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF5">
        <property type="entry name" value="LD29485P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23390">
        <property type="entry name" value="Beta-prop_WDR35_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24797">
        <property type="entry name" value="Beta-prop_WDR35_TULP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25768">
        <property type="entry name" value="TPR_IFT121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23145">
        <property type="entry name" value="Zf_2nd_IFT121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT121/TULP4 N-terminal" evidence="12">
        <location>
            <begin position="312"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="IFT121 second beta-propeller" evidence="11">
        <location>
            <begin position="679"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="domain" description="IFT121-like TPR repeats" evidence="13">
        <location>
            <begin position="1341"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="domain" description="IFT121-like zinc finger" evidence="10">
        <location>
            <begin position="1463"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="125"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM99145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1511" mass="169882" checksum="1E93611AA514C934" modified="2016-11-30" version="1">MNKDNGKLSLRNGLDNDMLEAKRKFANLKGKHLPLLPSPRQLRSPPKEEVSTCKQRRLISISQLHPFFEEIDHSSSVSSSGEADGPAGVTNGRVPRKTNADNDAGEGFIKWSALGSSSLPGLPTAVKSRDSLSSSGAESVKTKSDGSKSVTQSSSSGTGLNKESRSSLKSKLKKVPHNVKKQLSATGGFLWQHRCGKALLEEHNPPPNMPIVSPRDCPRCRHHSPVTDNIEEPLDTPVPVNKIDEFGDDGLIFGLPNWVDNSSLPDGNGNNLLTEIIEDAKQLLAQRSPMEWAMAAEYLYDPLGRDFRRFLCYLEKGIEMHLTNLQAVRCLKFSPFRSLLAIGCEEGTPELLELDYEKPLFHLKSDENLQLQPSQLYYVPLGSECRVLMNATLVGHSFDLRCLTWNNENGKLVTSDEIGVIIGWQYNKQQHCWVEELIDDKSTSMIRDMVVSPDGGKIAIGYEDYDENGSITGGILVGLLDGTQIFDRKFPGSQVSFVEWYTDSTLWVVVNQTIYAFDEHGDVGKVHRSIAMNSQPCEITTLLLKPKSSWITSDSAPEFAVIYRESCMSFYSSLHDKAPLRIHTQIVATCADWSPNGLYIAVGGMRVTATEDGFSNPQISMFNYEGKLLQILKIPEHTITSVSWHHDSLHLALATERQVYFASLRPMYKVTSNGTVHCYAYTRDFITQKISFWNEKTFITENIPGKVIDIKCFKAKFAVLCMDTQGVYHVFVFRETGVHQHHLCIITMEPFSITLTKNAVVCLAPNAVLNWNYNLNSSEKSNKLASTLRPTRQVHIDDFPGIIPKPGEKNDHLLRPAIDCTRCMHALGDRLCVARESGKLQFYALPTLGYLQTHKMELDGDICQKVLFNSDGSQLALLSMNGNLLICVFPEVSGQQLQVIICENVSNVSGMMWASDIPRQICVVEGHNLHILQDGIIMETICNIPSGSFLTHFENQLISLLNMDKIVEDPEHPSSSLVLKLYTATYSRIRELLENDEPIEDIANLLNVPFCHTTLRRTVADEALRQGRYELGESIYYEDKNFAAVQFLAKLKEIEEPDLQRAQVHCFLNEYDQAQHHLLRVERKDLAIKMWKDLGEWEKVNFLSGYTSEDVTDKALENQYDAFVESQDYEAAVEIANRLGYVDGLIICFIMLEDYEKLIALSEKLPLADPALSQIGDVLASVGLIEAAAQCYVAYGNPPAAMQLTVDTQQWDLAMKLSYDHKLPLIGPSLVKHVRSLIASEQFSPAIQILERCGKILTAGKLLVWKALCMLESEFANTLEVKKVFALAAKMLSKQKSRVNRESITCLNASFKDCDELDLEFLIPEDQLRIMTGHNEWCWSDPWRGAEASHFLNLTQRFLHRGMLGRAFKAAMHLRNFEDIVGSQRINTLVALTAINNYYYNVASNALLKLEAEDETFSSISFKLFKDQCPKDHGVNRIPCQGCEKYIPDIYSVCPCCNLQFTMCLFSACPIQNLKEMWTCETCSRHVELTKTDRFEYCILCHSKKSECKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3I0</accession>
    <name>A0A1D2N3I0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose 1-dehydrogenase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000255">
        <property type="protein sequence ID" value="ODM99781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3I0"/>
    <dbReference type="STRING" id="48709.A0A1D2N3I0"/>
    <dbReference type="OMA" id="NMGSINW"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43975:SF2">
        <property type="entry name" value="EG:BACR7A4.14 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43975">
        <property type="entry name" value="ZGC:101858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="305" mass="32747" checksum="0670C74D32FA04A1" modified="2016-11-30" version="1">MENRVIPEVAFTQTPRRKSVCERAALNFLEDLLLRFQTSEMATENISFKNKVVLVTGSSSGMGLAMNLRFAKLGAKVVVQGRDEKKMAEAVQQCTAASPFGYKPLQVKADVGVDADLINLVNKVIATYGQLDVLVNNAGVIALSPIDDPELMKKFDNQMKINVRAPVLLCSLCAPHLEKTKGNIVNISSGIGMRAFPGAIGYSVSKWAVMMITEGLALELGPKGVRVNTINPGFIENQAWHDKAGYGPEVGIAFKKGSPLGRNGTVQDIVNCVVFLTSDEASYINAVAVPVDGGITKTIQGTSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3T3</accession>
    <name>A0A1D2N3T3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stereocilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000259">
        <property type="protein sequence ID" value="ODM99724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3T3"/>
    <dbReference type="STRING" id="48709.A0A1D2N3T3"/>
    <dbReference type="OMA" id="ANCKHEL"/>
    <dbReference type="OrthoDB" id="8195838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026664">
        <property type="entry name" value="Stereocilin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23412:SF17">
        <property type="entry name" value="OTOANCORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23412">
        <property type="entry name" value="STEREOCILIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="669" mass="73018" checksum="50959079E33189A4" modified="2016-11-30" version="1">MLKKPFSLKRYTNLSAPARVLRDAGMLDSIDLPPEIRNLQPRKKGGDADYDNILDGLPSDAELRLAHGQGKKITAFELEKDKNLVGTLTPSQVAKIDLEEIPAVLAVVRKSKDGPQAQTLEALSKRFAEYVRSKSEDYDSPDKKLLKYMTAAEVSKLPATVLAYFIDHRQTSKLPPDDKLTGGTSKIDVPELAAIGQGVADLPPNEVEKLTPVALESAIQVIQGTSDDDDDGLKQRACLTPDQRKAWRKKIIENYGDPASWDPSTVSTLCCALGLLEEGDLRTIAPDALVTCQCVSDSKPPSHLAELKKALEANCKHELGEDVVEHPKKVVERVKSELTFDLDDLESQIITRRRRRSVDNLNCFKVRLTGSGSAFSKEQLETLDENELDNCLYELGVDPLTVDNARVIWKKLLASRNNQVKAEDVQNAGHILSGITINDVNELDLADPDIVLAFGKPLGLSKNVLEKLAMRLEQVKEKSVTQFDSEELVVTNNILCGFSSEQLTEIDADLLREALPVLKSIDPSCEQTRLAALAAVTVKADAFGDPKNWTSADVRGVGTILNGLPLSLVNTIPAESFLGVTPTVAAAMPETLLKELSAEQIANIPRFSAQAMSAEQVDAFGEEARDTLLSVIKGPTSSNGFSIQPQSQAFFLTATTLLIFRTAISYNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3V4</accession>
    <name>A0A1D2N3V4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_06739</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000245">
        <property type="protein sequence ID" value="ODM99943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3V4"/>
    <dbReference type="STRING" id="48709.A0A1D2N3V4"/>
    <dbReference type="OMA" id="MIAVFYM"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005332">
        <property type="term" value="F:gamma-aminobutyric acid:sodium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11496">
        <property type="entry name" value="SLC6sbd-TauT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037979">
        <property type="entry name" value="Na_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF265">
        <property type="entry name" value="TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00610">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00754">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5 10" id="KW-0769">Symport</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="461"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM99943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="633" mass="71456" checksum="895A4161AB8DD57B" modified="2016-11-30" version="1">MSEKPLTGDTSSEGRGLGFSMEINQLTNGSESGATSPKMTNAVVAQLHEDKDDDLPQRGSWGSKLDFIMSTVGLAIGLGNVWRFPYLCYKNGGGAFLVPYILTVILGGIPMFFMELAVGQFLTIGGLGVWKMTPIFKGVGYAAAVMSCWMNIYYIVVLAWAIFYFIMSFSAKLPWSDCSNKWNTDLCVNQTVRREDLCSTQLVNNVNVTLCSIGSRTNIPMRNLSDPVKEFWERRVLNISTGVEDMGEVRWELAGTLLLVWIMCYFCIWKGVRWTGKVVYFTALFPYFLLTILLIRGITLPGAFMGIKYYLNPDLSKLGDSQVWVDAVTQIFFSYGLGLGTLIALGSYNKYNNNVYKDALTVCCINSCTSFFAGFVIFSVIGFMAHTQNKPVSEVAVSGPGLAFLVYPSAVLELPWPTLWSCLFFVMLLFIGLDSQFCTLEGFITAMVDEWPHFLRRRKEAFIAVVCFISYLIGLACVTRGGMYVFQLLDSYAVSGLVLLWVIFFECIAFSWAFGVNRFYEAIRDMIGYYPVSWWKFCWVISTPTICCGVFFFSLISWSEIKYMDYRYPFVAHLFGWFTALTSMLCIPGYAIWLWRKTPGDFETKYKLLIRPQINLEEIRGPGNALSSEMTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4J6</accession>
    <name>A0A1D2N4J6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">E3 ubiquitin-protein ligase TRIM9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000226">
        <property type="protein sequence ID" value="ODN00190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4J6"/>
    <dbReference type="STRING" id="48709.A0A1D2N4J6"/>
    <dbReference type="OMA" id="ICIEMFA"/>
    <dbReference type="OrthoDB" id="295536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12889">
        <property type="entry name" value="SPRY_PRY_TRIM67_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.920:FF:000009">
        <property type="entry name" value="E3 ubiquitin-protein ligase TRIM9 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000178">
        <property type="entry name" value="E3 ubiquitin-protein ligase TRIM9 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF15">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="164"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="2">
        <location>
            <begin position="239"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="434" mass="47540" checksum="9E48E5A881783B27" modified="2016-11-30" version="1">MMDNCTSMEGLVTTQVDAIIAALQQRKEELITYIRREKDYKLRSLKAEVSSLTHRLQQTTALIHFCIEALKETDPSAYLQIGSLLLARVAHLEVAWACDDDSASSTDGSAIQISPGRTRSSVSSASSITGGYNSALFNPDFDLTLDDRSVLAAIRQLNFIQMKPPGPVQMIPEECTAENNSITVAWQPPPTSFVEGYVLEIDDGAGGTYREVYCGKETICTVDGLHFNSIYLARVKAFNSTGEGDYSETINLRTAEVAWFSFDPSGAAHGARLSNENCTVTSDSYEPRVVLGSVGFARGVHYWEYTVDKYDASADPSFGVARLDVNKEEMLGKDDKGWGMYIDHQRSWFIHCGVHSCRTEGGITAGSTIGVLLDLDKRQITFYVNDEQQGPIAFTNLFGVFYPAVSLNCNVTVSVHTGLDLPSDSETSDSGTRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5K2</accession>
    <name>A0A1D2N5K2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TM2 domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000200">
        <property type="protein sequence ID" value="ODN00553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5K2"/>
    <dbReference type="STRING" id="48709.A0A1D2N5K2"/>
    <dbReference type="OrthoDB" id="408511at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905068" evidence="2">
        <location>
            <begin position="20"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="143" mass="15858" checksum="EA5F9145560C733B" modified="2016-11-30" version="1" fragment="single">ILLLNLLIIPSSLEQSVQSKPSREKSTSATANGSSSAAPFSGGIANARSGGGSNVEEFNPTHPKVRCDYLPLDFLECDRLVDHFGNVTARDKHGFGCVKWGGEWYEEWNTQQRSCNAWMESNVSIIIISFLNKICHWNKNSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5W7</accession>
    <name>A0A1D2N5W7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOB-like protein phocein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000193">
        <property type="protein sequence ID" value="ODN00669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5W7"/>
    <dbReference type="STRING" id="48709.A0A1D2N5W7"/>
    <dbReference type="OMA" id="KECPAIA"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="234" mass="26661" checksum="EB8F537B47AB147F" modified="2016-11-30" version="1">MTMSEVKVIVRRNRPGTKGAEFCKWPEEPFEEMDSTLAVQQDPSNITAILTPPETQDEEVWKYEHLRQFCMELNGLAVKLQSECFPETCNQMTATEQWIFLCAAHKSPKECPAIDYTRHTLDARRLFTQQVSIRESSLGKLGSVCRRVYRIFSHAYFHHKTLFDDFEASSHLCRRFTSFVMKYNLMSRDNLIVPNMEDGAITTTTTTTTDAAPVATETTTKVTPPTGNTTESEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6E3</accession>
    <name>A0A1D2N6E3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tctex1 domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein light chain Tctex-type family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000184">
        <property type="protein sequence ID" value="ODN00838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6E3"/>
    <dbReference type="STRING" id="48709.A0A1D2N6E3"/>
    <dbReference type="OrthoDB" id="10260741at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21459">
        <property type="entry name" value="DLC-like_TCTEX1D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF7">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="31144" checksum="CF984A36D1448D8C" modified="2016-11-30" version="1">MADLRKSSVATSGGGASEEHERGTGSNRPSIDKDAAPEVHKDSVAVDREQRSGSGGSGDRPQSIAESSGQKRVSGERKRKDGTRNKMSFDVDELEEGLYIEVEDEEDVEEVVEYEEVPDDEVQPESVPEGGAKEGALKGEKLPGDVVAPDENIGYKIRPDLSQKFRPGTVQIIIERAIKELLEGKQFIPEECEEWIRLLVEDIHEKVKIQNYRRYKIITHVTMGERRGEGASSATRCLWDAEADCMATYTFLNVGTPCFATVQYMEYTFTEGNLPRKALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N754</accession>
    <name>A0A1D2N754_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Metabotropic glutamate receptor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_05776</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000182">
        <property type="protein sequence ID" value="ODN00905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N754"/>
    <dbReference type="STRING" id="48709.A0A1D2N754"/>
    <dbReference type="OMA" id="DDEEYAC"/>
    <dbReference type="OrthoDB" id="425344at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15045">
        <property type="entry name" value="7tmC_mGluRs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06362">
        <property type="entry name" value="PBP1_mGluR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000145">
        <property type="entry name" value="Glutamate receptor, metabotropic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.30:FF:000001">
        <property type="entry name" value="metabotropic glutamate receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.30">
        <property type="entry name" value="GPCR, family 3, nine cysteines domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011500">
        <property type="entry name" value="GPCR_3_9-Cys_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038550">
        <property type="entry name" value="GPCR_3_9-Cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017979">
        <property type="entry name" value="GPCR_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000162">
        <property type="entry name" value="GPCR_3_mtglu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07562">
        <property type="entry name" value="NCD3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00593">
        <property type="entry name" value="MTABOTROPICR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00981">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="536"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="648"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="729"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="761"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="14">
        <location>
            <begin position="536"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="855"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="944"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="895"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="950"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1005"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00054813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN00905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1035" mass="114787" checksum="50C49647975836A5" modified="2016-11-30" version="1">MSIKVRNGLLRSPGGVQSLEAMLYTIDYINNHGIIPGVKIGAYILDDCDKDTYGLEQAVDFIKGSISNIDDVDITGACADGEVHGGIKHRVIAGVVGAASSVTSIQVANLLRLFKIPQVSYFSTSPELSNKQRFEYFSRTIPSDKHQVKAMVEIVKQFGWRYVSIVYEESNYGIKAFEELERLLPENEICIAAKEKLVKDSGVAGEDSYERIVDKLVAGKAKGVIIYGSDQEVKELMRAVRKRNETGSFAWIGSDGWSARTLVSDGNEKEVEGTLSVQPKANAVKGFDEYFLNLNVRSNIRNPWFIEFWENHWQCKYPNSSKTPYNRDFNKSCTGYEKLTAENTNIEAQLQYVSDAVMAFAYALKDMHKSLCGGNSGLCEKMNPVDGTELLEYLRKAKFQGLSEDYFHFDEFGDGPARYNIIHFRRREDSGTFHWTKVGDYNEGVLALNMSGVRFSHGSATPPTSICSKPCGLGEATRYVGGDKCCWSCLKCVNDQIRNPLDEQECFACPMGTFPNAENTVCVPIKEEYLRYSDGWAIGAMTFAAVGCILTAAVFGVFVAHNDTPVVRASGRELSYVILTALFFCYALTFLFIVRPNDWICGVQQFMTGFVFTVVYAALLTKTNRIARIFQAGKKSARRPSFISPRSQLVICSMMVSIQVLINVVWMLLQPPRAKYYYPSRHDNFLVCEAYINHSYAVAFWYPLLIICVCTVYAVLTRKIPEAFNESKYIGFTMYTTCIIWLAFVPIYFSTGTQVALRVTSMTVAISLSAYVMIACLFGPKLYIILFHPERNVRQSMMAPATRYSTIASTAAAAGGGPASLNASALGGSGAITPIQMTALKHNHFENSTKSNLAMAHGAQQQPPPVKVDSSTQCEDGGKGQQKNAKSMDTRRPSVLQTTISTQTEDLCSSRSNSGRAGPDLGVDENQDLNLPSTERKTHKLCNHGHDQENFSTSEVATTTDSTLRSPTSSVDVALMHPHRHHHEPQPQRPQRISFRKEGQPPTPNQQNRSNRNTVLGDSKSVTIIVAKDSGDVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N783</accession>
    <name>A0A1D2N783_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF243 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000170">
        <property type="protein sequence ID" value="ODN01129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N783"/>
    <dbReference type="OMA" id="PYSHEHI"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040003">
        <property type="term" value="P:chitin-based cuticle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004145">
        <property type="entry name" value="DUF243"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31927">
        <property type="entry name" value="FI07246P-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03103">
        <property type="entry name" value="DUF243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00690">
        <property type="entry name" value="DM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905147" description="DUF243 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="DUF243" evidence="3">
        <location>
            <begin position="301"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="539" mass="58721" checksum="A11C38E7B86621E6" modified="2016-11-30" version="1">MGKLLVLTSCCFLLAASQSSYPEHLETNLLSFREEPKAGHIEAFQDHYVKQIFAKLLRRRLPNMPETVEPIKVENPESDDIEEPTSSGSVPEVMLLHSQLQNKLGWGSDDSGGNRNRIVVLNNPPNGFNQNQPSQSYGGPPPPPPQNGQSYGPPPPLRNNQNNQYGPPPNQNNQYGPPPNQKNQYGPPPNQNNQYGPPPNQKNQYGPPPNQNNQYGPPPNQNNQYGPPPNQNNQEFGPPTPVRQINQEYGGPPPPPPPQDSFQNNNGQQGYQPNQEYGAPQGNGGGNQNDLRVNQGNFGGYIQNSDNKGSLNQQSAALGQFSDNAPAPPQLPPTEIELPSPPERKTLVYVLVKKPQKQPEIRIRKPAPTQVSKPEVYFVKYKTPNQGGNNSPIENEAQELLSQVGGGDIGVGRFNGGYSDAVSMEPQSLQEAGRIAEPAGKTRESVGYPNTEYRAPPSMLNPNQEPMSISVYDRVRNGVPASSGGTASASTRAQQPQQGSHYRAPGSQPFDFPSGKMVSGRYIGMTSLTSNSLSNQYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7B4</accession>
    <name>A0A1D2N7B4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent RNA helicase SUV3 homolog, mitochondrial</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_05547</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000169">
        <property type="protein sequence ID" value="ODN01153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7B4"/>
    <dbReference type="STRING" id="48709.A0A1D2N7B4"/>
    <dbReference type="OMA" id="FCEMIIF"/>
    <dbReference type="OrthoDB" id="6692397at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17913">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1080:FF:000001">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000269">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000446">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041082">
        <property type="entry name" value="Suv3_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044774">
        <property type="entry name" value="Suv3_DEXQc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041453">
        <property type="entry name" value="Suv3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18147">
        <property type="entry name" value="Suv3_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18114">
        <property type="entry name" value="Suv3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="331"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="656"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="674"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00069703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN01153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="691" mass="77861" checksum="B9D5541DDD771356" modified="2016-11-30" version="1" fragment="single">ARIVTSTSWSVLRSTTCSSNFNLQKVQVRFKKSSAKQPPEVKGSATNTQNGVSHLFVPVPVKATEKMGPWVLNKFFRRSEVKLLSAEHGLDNYLFHQAFISFRKLCLDADTLPVDLHILFSDISHGAAHVDDLFAYFVKHAKQIFPHLECMDDLKKISDLRSPANWYPEARVSPRKIVFHAGPTNSGKTYHALNRFFEAKSGVYCGPLKLLASEVFQKANEKGTTCDLVTGEERRFGNPDQSAASHVACTVEMTSVVNQYEVAIIDEIQMLRDQQRGWAWTRALLGVCADEVHLCGEAAAIELIKSIMITTGEDVEVHKYERLTQLEMERAALGSLSNVKPGDCIVCFSKNDIYRVSREIEGLGHEVAVIYGSLPPTTKLAQAQKFNDPENSCKILVATDAIGMGLNLSIRRVIFYSLVKPTLNERGEREMDVISTSQALQISGRAGRYGTQFAHGYVTTFKNEDLATLEKLLAASPETLEQAGLHPTADQIEMYAYHLPSATLSNLMDIFVSLCTVDDSLYFMCNIDDFKFLADMIQHVPLPLRARYVFCCAPINRKMPFVCTMFLKFSRQYSRNEPITYDWLCQHIGWPFNAPQTIMDLVHLESVFDVMDLYLWLSYRFQDLFPDSSMVRATQSELDSIIQMGVFNITKLLKSGESNTTSPSFDEGEMALPKKQKYIRGRRYGSKKETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N925</accession>
    <name>A0A1D2N925_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Synaptotagmin-17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000141">
        <property type="protein sequence ID" value="ODN01737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N925"/>
    <dbReference type="STRING" id="48709.A0A1D2N925"/>
    <dbReference type="OMA" id="VVINERH"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017156">
        <property type="term" value="P:calcium-ion regulated exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF348">
        <property type="entry name" value="SYNAPTOTAGMIN-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="138" mass="15736" checksum="B4F2D4697BCB80A0" modified="2016-11-30" version="1">MVVKDFDKYSRHRVIGQVLMPLVDVNVLKGVYFWSPLEAVQAVSQEDLGELLFSLCYLPAAGRLNVDILRAKQLTPTDLVGGAAPYVKVTVVINERHIKTKKTSYKKYTLDPVFNESLRYEAFAILALYIHKFLFSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N985</accession>
    <name>A0A1D2N985_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">G-protein coupled receptor moody</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04888</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N985"/>
    <dbReference type="STRING" id="48709.A0A1D2N985"/>
    <dbReference type="OMA" id="CITSCIC"/>
    <dbReference type="OrthoDB" id="10044919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24228">
        <property type="entry name" value="B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24228:SF74">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN01812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="216" mass="24518" checksum="289A9A1E7514AF87" modified="2016-11-30" version="1">MRLYRTRYLGVMILLIWLGSFGALVPTLLGVWGKFALDEEIGSCSILKGENGTSPKKFLFIIAFVLPCCAIIVCYARIFFIVRKATANLRPVEIPSSAGNVNHTTILRRSSARPSIAVIHQRGKMTNKDRKLLWMILVIFGAFVVCYLPITIFKAVVKHTNSTWNIFGYLLIYMTTCINPLVYVLMSSDYRQAYTNLFLCRKDWNLSSRTSNSNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9Z4</accession>
    <name>A0A1D2N9Z4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_04642</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000126">
        <property type="protein sequence ID" value="ODN02074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9Z4"/>
    <dbReference type="STRING" id="48709.A0A1D2N9Z4"/>
    <dbReference type="OrthoDB" id="152385at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF6">
        <property type="entry name" value="CONTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="353"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="250"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="438" mass="49207" checksum="B45E0EA5F6ED7911" modified="2016-11-30" version="1">MLVKQSYETQVQVPRTVNGFPAILECVVNPSYMRDYVLVTSWVRDKSYNILPTASIESSDNKYHMMSDGRLLIWQVGPQDARFTYQCRTLHRLTGQTSVSPPGKLVTFDLDRPSRPMIQYRMSSIVAKENEQVVLPCFAHGLPQPSYRYGIFYPLMKPEKERLRNLYIFTPPFQETCEHSSVLVGRKKRETTSSHNLIMPFHKQSQCSKWFKKEGIRLTSVIDDSTDESGHNFMFLSSSSDSSRNIQQQHQSSVSSSSSYRHDSSSNSHSILSPNSNSGLDSSSNIGGASSSSGSNSESSSTAILATSSGMRLRHGALIINSVKVANKGLYLCNVSNSEGSELLEVELIVRSPLTVNLHPKKLSVDLGKSAEFTCSIVSGDSQSSSSSTVHWLKDGVPFTLRCRNKWGKQSEVYWSQQNYHSICDQRRPRHVSMYWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAL5</accession>
    <name>A0A1D2NAL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAL5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="88" mass="9841" checksum="6BD1D41A33AF9694" modified="2016-11-30" version="1">MVLSSPTPLHTIQMPKNYDVPVRQPKTLNMTMGMDFIKDMIQNGIPFRPTPPQFPSLKNLFNRSNGTQLSWVPLGSLIFNNNGKIIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAQ2</accession>
    <name>A0A1D2NAQ2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">cardiolipin synthase (CMP-forming)</fullName>
            <ecNumber evidence="13">2.7.8.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_04318</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="EC" id="2.7.8.41"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.41" evidence="13"/>
    <dbReference type="EMBL" id="LJIJ01000115">
        <property type="protein sequence ID" value="ODN02334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAQ2"/>
    <dbReference type="STRING" id="48709.A0A1D2NAQ2"/>
    <dbReference type="OMA" id="HNAQRIL"/>
    <dbReference type="OrthoDB" id="10020554at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043337">
        <property type="term" value="F:cardiolipin synthase (CMP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000005">
        <property type="entry name" value="Cardiolipin synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00039001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN02334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="307" mass="34205" checksum="807C4DEE17AE79E5" modified="2016-11-30" version="1">MLNLLNLHNVATRSKFQLTSLLIRNSQTNFLKPFRSFQQSCYLCGRLWPSTRKDVRNRKLEQNQIQGLVSARAPRNGRVRNAGYCVMKASKPSSKENIWTIPNALCFVRIGMTPFIAYMIVQSQYGPAIGLLAVAGVTDLLDGWIARVVPGQSTVMGSFLDPMADKILVGTLFLSLTYMDLIPVPLTVLIVGRDAILIAAGFYIRYQSLDPPKTLSRYFNVTLPTAQLAPTFISKVNTGLQLTVVGATLASTVLSGYDLHPYLQILWYTTAATTICSAVYYCFAKDTVKLLRETSSKMKFRARKKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB77</accession>
    <name>A0A1D2NB77_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">39S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_04160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000108">
        <property type="protein sequence ID" value="ODN02503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB77"/>
    <dbReference type="STRING" id="48709.A0A1D2NB77"/>
    <dbReference type="OMA" id="WIENTDA"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000005">
        <property type="entry name" value="39S ribosomal protein L4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00082711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN02503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="36558" checksum="E7EB296C70C42D64" modified="2016-11-30" version="1">MLRQICTTGGVLSSTSCNSFRILSGNVIPRSASRFNSLVDSFTLKKEPKIEVPVPVVPEEEVDNALITKSPLPLITSRELKYLPYGRTARQAWVESLDTLEERKLGLVDLHPDVFGTFPRIELINTNVKWQQDYKKVNWAWLPRRSELAGSQRKPWPQKGTGRARHGHRKSPLWYGGGKAHGPRGPKSLYYMLPFDKRLHGLCSTLSVKLAQDDLKIVDTLDIPTDDPKYLEDLVDQRKWGVSVLYVDDSDIAPKNLALATDTIGHMNIMPVYGLNVFSMLKHETLVLTLAALNKIEDKLIFHLNRHNPFPPTAQKIPYGKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBA0</accession>
    <name>A0A1D2NBA0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DBH-like monooxygenase protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000108">
        <property type="protein sequence ID" value="ODN02527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBA0"/>
    <dbReference type="STRING" id="48709.A0A1D2NBA0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042420">
        <property type="term" value="P:dopamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOMON" evidence="1">
        <location>
            <begin position="53"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="199" mass="22596" checksum="B20FBACC972E632B" modified="2016-11-30" version="1" fragment="single">MANPQKYKIETWNHLIIFTTFLITSFTCKVFAQSVPNIPVSQFQRREVLDPNVGLALEWSVNRESNTINLQVEIESGNGNFALGLTRKGHIEGSDVIYFEVENGIATPSVSDMFGEDNTTIVQDTNQDWRQISSSTSQNLIRIQIQRNLDTCDEQDLKIDESLIKVVWDYGVNSSLPSQFDVKGVEFVYFTDTRVYSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCF9</accession>
    <name>A0A1D2NCF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein IWS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_03756</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IWS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000092">
        <property type="protein sequence ID" value="ODN02947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCF9"/>
    <dbReference type="STRING" id="48709.A0A1D2NCF9"/>
    <dbReference type="OMA" id="KIRATEW"/>
    <dbReference type="OrthoDB" id="21124at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.930.10:FF:000001">
        <property type="entry name" value="IWS1, SUPT6H interacting protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051037">
        <property type="entry name" value="RNAPII_TF_IWS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010:SF1">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="11">
        <location>
            <begin position="566"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="648"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="650"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="768" mass="84972" checksum="A568224ED2CBC053" modified="2016-11-30" version="1">MDVNEDGPTQVVPGRSWNAENEDDADEVGSTQPASSNRVDEEDFGPTQVIPRRLSVHEEEEDLGPTQAIPRRTSVHDNEQDEEDLGPTQHVPRGTIVDDSDDEAVDETGPTQRIPGKMAESEGEGDDTGPTQRVPGRSIENDDEIDEIGPTQRVPGRPVVDNESENEVDETGPTQRVPGRTVNSSEDENAVSSQIQQSLETPSSNLDESEVLSQTQVIPKGVSNDDEDIDSGPTQVIPRRSSKADADEAEIGSSVNIQEKRKSRSRSRSGSGERKARKSKLRSKSRSRSRSGSRASSASGDEVGVLKKKRRRIGSESRSRSRSRSRSRSGSRASSKASSRVGRSKKKRARIGSGSESGSSRRSSVASKRSGSRGSRRSRSKSKSRSRSRSRSRSSSRSSVGSRASQRRARSRSGSRSSRASSSGKSPKPATTQNEEGEGASTSKPEETTEGATAVLPDVSDSDDSGPDDDNRKHSGDFVSDFELMLARKKEEKGTRRKRKDIEIINDNDDLIAQLLGEMRIASEEDRELNKVSKPATKKIALLPTVMHHLRKHDLQMAFIECNVLSILTDWLAPMPDRSLPALRIRESIMKLLTEFPPIDQGLLKQSGIGKAVMYLYKHPKETKPNKEKAGRMISQWARPIFNLSTDFKAMSKEEREQRDLEQMPKRRRMSDDATTSRSTDMSQTFTGEGGALRPGDPGWVPRARVPLPSTKDYVVRPKWNSETDISRSNRKQSTRLDKHIRNFAEKKKMAKAQRAVSISVEGRRMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND33</accession>
    <name>A0A1D2ND33_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000084">
        <property type="protein sequence ID" value="ODN03173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND33"/>
    <dbReference type="OrthoDB" id="7447462at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="157" mass="16043" checksum="76B649C3BFA00C86" modified="2016-11-30" version="1">MMIMEMTGSCKVYSKSDIIATTASETATSNNNSSSNATVVSASATTEDLITDVTSSTGSSKITNSTTVSSKENGRAGNSVDCRATLAEKEVTSLKEQLANHGGTGGGTGGSSSTGAPVAATAMAPPPPEREDQLISPSQHKNDYEMVAAKDKEVSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDR5</accession>
    <name>A0A1D2NDR5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03270</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:36684"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000075">
        <property type="protein sequence ID" value="ODN03408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDR5"/>
    <dbReference type="STRING" id="48709.A0A1D2NDR5"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12349">
        <property type="entry name" value="ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12349:SF2">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="2"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="461" mass="50267" checksum="AB4BE866476E1481" modified="2016-11-30" version="1">MIQTFDHHCPWVNNCIGRRNYRFFFMFLMSLSVHMIAIFSLCLIYLLQHMDNMSEPSTIIAVSVMVIISLLFIPIFGLTGFHIILVSRGRTTNEQVTGKYRGGFNPFSRGCCKNCCLTLCGPNFPGIKRPQYLNTSDQDLGLQASQSLDCEPTPPIQRHGSKTNFFLPPTGNQEDPSAPQMRHTRGPCTHGSPHPNRQRNGEGPRSRSQTPESLSSPSDTAMGTETITSPTLHQKIRAIGGVPTPFAVSASPGIRRSNPPTPTQAGARPDYVVGAHECMVPGPSIGRPVYPGYYVDDGYVAAPPGDQRRVSSSTEMMYERHYHAPVAGINRESSGPIRELASSPQNGVYLWKDNSPTRVANQNFNSTNSNYFHSNPTSPMQPTIMNCTQNNAMFARGYAHPSSEGSLIGFPGSPSFSPAPVPTSPNGRRKMYGGVQPQGVVGVAGVGVTVGGWRCETKSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE95</accession>
    <name>A0A1D2NE95_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5077 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000079">
        <property type="protein sequence ID" value="ODN03296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE95"/>
    <dbReference type="OMA" id="SAMWILE"/>
    <dbReference type="OrthoDB" id="7769523at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021862">
        <property type="entry name" value="DUF3472"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031712">
        <property type="entry name" value="DUF5077"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11958">
        <property type="entry name" value="DUF3472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16871">
        <property type="entry name" value="DUF5077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5077" evidence="2">
        <location>
            <begin position="11"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="428" mass="47546" checksum="30A7F00BE6ED7B5B" modified="2016-11-30" version="1">MCSNKKSVCIIPFGGNAFITKSESSAKELITPCGIASWTSSSTVISLYFHSQYPGRVLAALRLRVPEGSSNVNVILAHNDSSAVTPTAAREVSLQGADFQLVNCGMFSIPKAGYTRLDIQGVEKTGPFYAEVSHVVLVSEFDSLLEPMHLRFVDDPADFYFGRRGPSVHLSYPLPEASDTEYFYNEIYVPKGQDLVGAYFCAMGFSGGYFGIQVNSSEERRVLFSVWSEYSTDIPGEIPEEYKVNLIRKGEDVYVGEFGNEGSGAQSYLQYMWEPEKSYKFIVHARPINEEHTMYTAWFNDGSSPNAWNLIASFDKPKVSTFFKGPYSFSENFIPEMGYQERHCLFANQWACDSTGNWTELTKANFTADATAAKETRMDVSGGVGIDGDRTKFFLRNCGFFSDRVPPGSPFERESSGDLPPVDVSLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF49</accession>
    <name>A0A1D2NF49_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="12">ARD'</shortName>
            <shortName evidence="12">Fe-ARD</shortName>
            <ecNumber evidence="12">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="12">ARD</shortName>
            <shortName evidence="12">Ni-ARD</shortName>
            <ecNumber evidence="12">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_02799</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="12">Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="12"/>
    <dbReference type="EC" id="1.13.11.53" evidence="12"/>
    <dbReference type="EMBL" id="LJIJ01000060">
        <property type="protein sequence ID" value="ODN03881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF49"/>
    <dbReference type="STRING" id="48709.A0A1D2NF49"/>
    <dbReference type="OMA" id="NNYIKLM"/>
    <dbReference type="OrthoDB" id="1867259at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010308">
        <property type="term" value="F:acireductone dioxygenase (Ni2+-requiring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010309">
        <property type="term" value="F:acireductone dioxygenase [iron(II)-requiring] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000031">
        <property type="entry name" value="1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03154">
        <property type="entry name" value="Salvage_MtnD_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027496">
        <property type="entry name" value="ARD_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418:SF0">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12 13" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4 12" id="KW-0533">Nickel</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN03881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="21815" checksum="B04368E021EE1FEF" modified="2016-11-30" version="1">MVRAWKIKESELDENKWEASSENISYLDLETVKQTTGVLYWKLDADTYKEDGSLEKIRKDRGYSYEDEIEVSSEKLPNFEMMIKKFANEHLHTDEEIRFILDGKGYFDVREALTDDWVRIEVVKGDLIILPAGIYHRLVLDPVRYIKAKRLFVGEPIWTAYDRPADEMEARQKYLAEIKEVNRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGB9</accession>
    <name>A0A1D2NGB9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein numb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_02423</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000049">
        <property type="protein sequence ID" value="ODN04272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGB9"/>
    <dbReference type="STRING" id="48709.A0A1D2NGB9"/>
    <dbReference type="OMA" id="KFTNPWD"/>
    <dbReference type="OrthoDB" id="10070446at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01268">
        <property type="entry name" value="PTB_Numb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000031">
        <property type="entry name" value="protein numb isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016698">
        <property type="entry name" value="Numb/numb-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010449">
        <property type="entry name" value="Numb_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47368">
        <property type="entry name" value="NUMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47368:SF2">
        <property type="entry name" value="PID DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06311">
        <property type="entry name" value="NumbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00640">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017607">
        <property type="entry name" value="Numb/numb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01179">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PID" evidence="4">
        <location>
            <begin position="42"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="529"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN04272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="615" mass="66170" checksum="9D1578F990E131E0" modified="2016-11-30" version="1">MQRMDRLRRSLRESFRRKRDGPESSKPHQWQADEEAVRTGNCNFHVKYMGCVEVFESRGMQVCEEAMKVLRQSRRRPVKSTLHISGDGLRVVEDDTKGLIVDQTIEKVSFCAPDRNHERGFSYICRDGTTRRWMCHGFVASKDSGERLSHAVGCAFAVCLERKQKREKECGVSMTFDSKSSTFTRSGSFRVGTATDTLSTKSLSPPPSAGPIANKSSTSTTTSTTTTSSSASGNPHAIERPHAPTKMLERQGSFRGFSQLANRSPFKRQLSLRLNELPSNLQRTQQSSVDILTSNNIIPISAPFVPVGGVIPEVPSHGGSTENTVVPPPPKVENKDLVSQLCQQVTQGLSMLAANHDDIKNVTLTTTATNSFPTKFTNPWDDEVRGTPRSSALPVFNTAPLAKANSVISTGSPSKIQPVSQSKTTSVADTWFNNLTQSHEPKAPLQSKISPIRENSGLIIEKSAVTSSTFSSNFTQQNISSVSNNITNSSILPSANSASITGSNNPASVMSSAASTAATATQLNSLSGVKNSASFSHNNPAAAPGVPPSTTTPGQPTQPGLGTTGVARPTYRGAPTRSQSLGADPFDATWAEPLARTGQAPTNPFVRQQTFQVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGD4</accession>
    <name>A0A1D2NGD4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease P protein subunit p30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02387</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGD4"/>
    <dbReference type="STRING" id="48709.A0A1D2NGD4"/>
    <dbReference type="OMA" id="TTRICIR"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002738">
        <property type="entry name" value="RNase_P_p30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01876">
        <property type="entry name" value="RNase_P_p30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="33156" checksum="977E18283DAF3953" modified="2016-11-30" version="1">MEKCIPPRSVFGKQCFGDLNIPTGPKCRHVCEAAIAVGYKLLALNTPVVATSCLPQKPGGGKKAKKRKLEEKTGGILSATAAQTGQDGVPPPKRQDWIADLMEKHKDVRILQRLTVIFYDINHLQTVLSQENVALYEIIAVVPTNHEALVSCVISSLVFDVISFDIEGPHWINKVKLNRQKGKVAAEKDVHFEITYSPSFHGDEPLENMVYIADRLKEDICTRKIKNIIISSGASAPDEIRSPQNVLGIGYLLGFDETTTRICIREHVERIVKKGDSRKFGKSWVAFTPTEQKEKVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGM6</accession>
    <name>A0A1D2NGM6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">[histone H3]-dimethyl-L-lysine(9) demethylase</fullName>
            <ecNumber evidence="7">1.14.11.65</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02274</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:60188"/>
            <dbReference type="Rhea" id="RHEA-COMP:15541"/>
            <dbReference type="Rhea" id="RHEA-COMP:15546"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
            <dbReference type="EC" id="1.14.11.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.65" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000044">
        <property type="protein sequence ID" value="ODN04414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NGM6"/>
    <dbReference type="OrthoDB" id="1667110at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140683">
        <property type="term" value="F:histone H3K9me/H3K9me2 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000004">
        <property type="entry name" value="Putative lysine-specific demethylase 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045109">
        <property type="entry name" value="LSDs-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12549:SF38">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING HISTONE DEMETHYLASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12549">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="JmjC" evidence="10">
        <location>
            <begin position="1353"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="209"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="306"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="718"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1130"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1595"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="422"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="718"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="743"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="769"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1595"/>
            <end position="1611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1636" mass="181969" checksum="92676AC7D7E22EF9" modified="2016-11-30" version="1">MEPGDLRINSRLRDDSGVPRSSPSSSYGAVNEGNSVLQFRSHIRPAVITDGRLHHMPSSMAGPPLVIDRMVSSRNEPVKVWRDPTLMNSSEIRHVVSMQHSGVVHLTHPMVAHSNVNTGGAVYLHHDNKSIENAASRGPPNAPHEMRGRAPVVYAPPANAAKQHMDAWRHQAVLQQNSKDFRVNLSSKSTVEQAVHDHFVESLRLAQLKGSTSQPAVKQEERPSSHASGAHQQQRFYPPPPDKRHHEHPSSQVIYQIHQHQAMHKPELPAPPPLRSEAQYCPPGGGMESGRKHQIYGAPEVIVRPHAATQQQSSSIRYESEPDILPSDNCVRYRNHPPVPRRPTSQNDLHLERNRSPFGKPGPPASSPNSYHGYPQAHVSKHKVNSPAPPHIYGKPGPSTRPYDMSNDPSGPLPLTSKGGLTRPSQSSPTSYSHTSPSLPQHDVRKSDVAYYMYNNVPPGFQQPSLSPHAHMHSIQTQPLDLGGKRKVEDEVYKAKIQEPSDYSGVNPYFGSRKPEDPNMRPRIPQSHPHHIQNSSIPHSYTFADSMPSKRKIEEVSMSMHLDPKKVRCEAPKVSVGNVMMGRKEHEMKAVGASEREFLLDNSRLQMDNQGPLPLNMSESASKVKLEATSPAPLPFDMKKSTVKVGAVDIKPGVATITQGPLCNGKHKESTTEQKAASPPVDIKFDSQIITKVKIEAASLSAVVPKKAWVLQWHEADGSNDKTVNDDNTKVPKNDADVEVSNGCATPQSTSATENGTKDDRNGKLLNGHTLSNTESDSNKNTSVTNTQTFNGFGKERLNDSDIGSENESDNSNKEKVSTDSNPSPMKKNGRKGKDCSQASPKPDLRKDGLCKRPPVSQLKKTGESFIQAETCNRVTPKIAKCRECRWHPSARGSKKQSGAYCRFYGFRKLRYTKGGSLTVAGFSDPFTDPSKITEHDQFRLWLPSNVTPEGLSIEISKFLLSQLCDQFCDLVQQEEEARSLARTQELSEIAWKPLLKGVREMCDVCDTTLFNFHWACGKCGFVVCLSCFKARKDDSEGERAPENAGKDRDEFQWLLCSNRCAHELDKLMLVQTIAGDALTELNKKMHSICESRDIPQKCGCGNPSRKSQQEEQLVAAVKVTNEKLKSETIENSAEDKCKKSENDSDAKSKNDIDNSRLVVEEDAKTANGCSTNTDAEEGIELKYFKRLKPIETIRKKLPISQKTFATTESTVLYPNVKHSWLCDGKLLRLMDPRNPENKSIFHEQWKRGSPILVSNVTEKLDKELWTPESFSKDFGEYKNDLVDCLSGKVLANQQMKKFWEGFTCVDNRMLDDEGEPMLLKLKDWPSIDDFAQVLPSRFQDLMDALPLPEYTLRDGKLNLAARLPAEFMKPDLGPKLCIAYGSGEELDKATTNLQLDVSDAVNVLVHCEPSQDEDATDYEKAVLDAIKESDCDVVTINRVLQKKEVPGALWHVYDAKDADKIRDLLNKVAVEKGASVEPHHDAIHDQSWYLDKTLRKRLMTEYNVCGYPILQCAGDAIFIPAGAPHQVRNLQNCIKVAEDFVSPENISHSFYLTEELRNLSKDQPTFEDKLQIKNIVYHAVKDAAAVLLLQTTEKSETAPQNSQEDASTALSKDCQFHPSTSPQNPAALVVNSATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH71</accession>
    <name>A0A1D2NH71_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Fragile X mental retardation syndrome-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_02109</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Neuron projection</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Stress granule</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Perikaryon</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Synapse</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FMR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000040">
        <property type="protein sequence ID" value="ODN04611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH71"/>
    <dbReference type="STRING" id="48709.A0A1D2NH71"/>
    <dbReference type="OMA" id="DQQQRGY"/>
    <dbReference type="OrthoDB" id="424249at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043204">
        <property type="term" value="C:perikaryon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045182">
        <property type="term" value="F:translation regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048170">
        <property type="term" value="P:positive regulation of long-term neuronal synaptic plasticity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099577">
        <property type="term" value="P:regulation of translation at presynapse, modulating synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22425">
        <property type="entry name" value="KH_I_FMR1_FXR_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22426">
        <property type="entry name" value="KH_I_FMR1_FXR_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22427">
        <property type="entry name" value="KH_I_FMR1_FXR_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20402">
        <property type="entry name" value="Tudor_Agenet_FMRP-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000004">
        <property type="entry name" value="Fragile X mental retardation 1, isoform CRA_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000054">
        <property type="entry name" value="Fragile X mental retardation protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008395">
        <property type="entry name" value="Agenet-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040148">
        <property type="entry name" value="FMR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040472">
        <property type="entry name" value="FMRP_KH0"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041560">
        <property type="entry name" value="Tudor_FRM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10603">
        <property type="entry name" value="FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10603:SF7">
        <property type="entry name" value="FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05641">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17904">
        <property type="entry name" value="KH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18336">
        <property type="entry name" value="Tudor_FRX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51641">
        <property type="entry name" value="AGENET_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <keyword evidence="13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="11" id="KW-0770">Synapse</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Agenet-like" evidence="17">
        <location>
            <begin position="73"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="398"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="441"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="455"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="649"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN04611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="673" mass="74565" checksum="9D440A10BDD2376B" modified="2016-11-30" version="1">MEDVAVEVRGENGAYYQAFVREIFEDGHVLVSFENNTSEYDDNSVLPEQRLPFARVRLPPKPNGTQGPFVEGQEVEVFSSPGDSEVGGWWRATVKIVRQDLYVIQYSSDAKSTEIVESHRVRAPNPNPPIGKSTFHKIELPVPDEICEYLNTLSTSAKIESSHREFQRLTGAGSCRFIPDRRVLCLISQSEDTVKKVNLLKEMHFRSLNQKALLLKKTEEAAKQLESMRMHSGANFSEEFRVRDELMGLAIGSGGSNIQQARRVEGVTNIELEEQTCTFRIYGETEEAVKKARSLLEYNEESIQVPISLVGKVIGRNGCIIQEIVDKSGVVRVKIEGENEPNPSIPREEGSIPFVFVGTVESIANAKTILEYHLNHLKEVEQLRQEKLQIDQELRSYHGPGAVGTMHFPSRRTDRPYADLDGLGPRGRGGRGGLGRGGPPRGSSTRGRGSYGRFRSSDGERFQSDHDLQRYSNYTSTKYRDGPSASNSRRLTNGYGSRQSTPGDVEERLNGRGDGRRFRGGRERSERGGPPPPRGRSGRGRSNTNSDQDFRRRGRDDEEPFTEENVVVVENNINDRDDGETRRRSAPARGGKKSSSGAAGDHSSPAEDKEEDRNDASSTNTGSAPGPRPQREQRSRGRKSGKESSSGSIPANSHNHTSAPDSQISAIVNGDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHG3</accession>
    <name>A0A1D2NHG3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHG3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="273" mass="30329" checksum="4DC60F697C9421D0" modified="2016-11-30" version="1">MKWKVILMERIRRELRDAASRGVKHEWEKSEMFKKFANCDLDSFFDTLRSSASESSEENDGESCGDTDNGKGGSGVCINYPKYIPSYAVAGPSTKSEDSEKVDAANQPVQSNFTVTDVTSGASTPIEQILKIPVLLASRRVQSESSGTNNSDTDESELGQHDEKVASNSVATEPIFGASEAYPIRIDNLIQSSATYWEQVKRNIDDILNELESSKEDVPLEEKGSHIDKIRNHLKSQLSDIKGIEKRLRATGKHILSASKKKNQARESEKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI38</accession>
    <name>A0A1D2NI38_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI38"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905591" evidence="1">
        <location>
            <begin position="21"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="129" mass="14846" checksum="1AD9688DEACE619F" modified="2016-11-30" version="1">MKYLKIYVVCLLALAACVWGKEKENVDLDDYIEKPAKNDKNEELATAETGYYGHQPHYGVSYHHHHQPHYGHHGYGHAQTYYRAYHGHGYGHHHQPYGGHVGSAHVSYGTHIQHGHPHHHHHGYYGYHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NII5</accession>
    <name>A0A1D2NII5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ataxin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ataxin-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000033">
        <property type="protein sequence ID" value="ODN04915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NII5"/>
    <dbReference type="STRING" id="48709.A0A1D2NII5"/>
    <dbReference type="OrthoDB" id="2275718at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00600">
        <property type="entry name" value="Sm_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045117">
        <property type="entry name" value="ATXN2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009604">
        <property type="entry name" value="LsmAD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025852">
        <property type="entry name" value="SM_dom_ATX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854">
        <property type="entry name" value="ATAXIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854:SF7">
        <property type="entry name" value="ATAXIN-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06741">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14438">
        <property type="entry name" value="SM-ATX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01272">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LsmAD" evidence="3">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="404" mass="45115" checksum="912DB36A8B134020" modified="2016-11-30" version="1">MTILVGSSAEVRTRDGEVYEGIYVAFSSAMEILLEAAHLVTDNKDDDSIEKHFDVLVIPSEKVISMKCVNADLTYPTREFATDTAISSGRGGGMGSKELTPWECSEDTPEELTLDAGSTPGNTVGNGWEAKDMFKKNEEKYGVVSTFNHDLSGYTTKVDKNDTEFKRLEEQANQIAREIEGGTASWDRTQVENGDEEEAFSAVVRPRNNASSTSVNNNNNNNTSSKWQIYTSFAKSKQLGAKCTSAFAVPSSIKQNGPAHTNNNSSMNRKTIYNQNQNPRNNYGAPPNAVYHQDRRNFDSRRAPPPNQQYGNAPNHEVRRPEDSGPRPRMPNKVPSERKDPAKLKEFGNAFRFQSSDTSQMRRPPGNPPPPQVGMRHMLWLQTLLRQLEIQVLQLQLCRSLPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJJ8</accession>
    <name>A0A1D2NJJ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJJ8"/>
    <dbReference type="STRING" id="48709.A0A1D2NJJ8"/>
    <dbReference type="OMA" id="FITYFEM"/>
    <dbReference type="OrthoDB" id="6234762at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009801">
        <property type="entry name" value="TMEM126"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16296:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 126A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16296">
        <property type="entry name" value="UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07114">
        <property type="entry name" value="TMEM126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="243" mass="26875" checksum="7FF4CF37F593D0F4" modified="2016-11-30" version="1">MSNEAVNVEGTPSKMKYYIERYPQDASSSNTGTLAKGGRDNHFNSIVEILMTWPNRDIWPFKVAVPLLVVSGGLPGYILNKGFRTGLLLSNVGRISSKFATVGIPGIVSGLVHATFISSDIAEQRTPCPVCVQVRSAAIQLAIAVVYPVFLTPIVNFHLASGVRGIYLPKINKNPREVFLYAYDLFRTVKNRYFAAAALQVVIAMGVTHMEQTCFNDVVLPIITGEKKFSKETRKIEFEYIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKT4</accession>
    <name>A0A1D2NKT4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G2/mitotic-specific cyclin-B2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_00862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000015">
        <property type="protein sequence ID" value="ODN05851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKT4"/>
    <dbReference type="STRING" id="48709.A0A1D2NKT4"/>
    <dbReference type="OMA" id="INWISEV"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20507">
        <property type="entry name" value="CYCLIN_CCNB1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="261"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="355"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="359"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="492" mass="54684" checksum="CE1CFF5F5D4D2C95" modified="2016-11-30" version="1">MATFLRTNSSSSVSSLSSVGSDNVEVVGKGLKTTQAGGRNLVQRTRDALGDIGNRLKKNPVAIGGKAPALKKATTGAKKEFAVPTNRPPRAVPKIKAQSGTKTQSKSVSKPKKETSSGGDSSENQIAKPECVLKLDANVKAGNYTEQTISAKIEDDKENVPISAPKLEVAKSPSSKHGEEVVEIENEYNPKLSTEVSVESFSTERLDIVNIDVDEWNPLLVQAYITEIFDYVFELEKKYPVRIRYLEGRLINSRMRAVLLDWLIEVHTQFGFMPETLYMAAKIMDRYLQADRNVTRKQLQLVGVTAMYIAAKYEEVCTPAVQDFAAVSDNAFTIGDVRKMEQDMLKTLSFDLAFPPAVLFLRRFSKAANANMSIHSMAKYIMELSLVDYAACHLFPSEQAAGSLALALLILEDKKSLVELWNPTIQHYSRYSLETIKPIISLLAGIVSRAQEESQKLKAVHTKYTKKRLSYASLAPELKVELWRTRVLKEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKT8</accession>
    <name>A0A1D2NKT8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat-containing protein 59</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKT8"/>
    <dbReference type="STRING" id="48709.A0A1D2NKT8"/>
    <dbReference type="OrthoDB" id="1394818at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF42">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 18-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="549"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="553"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="600" mass="68704" checksum="F52F0C53BD5DD95E" modified="2016-11-30" version="1">MKFTPTEAPSEALFERIRSQQGSGKLDLSLCEITKIPLKAIQEHYDDKLNELDLSFNLIRYMKPLFVLDMEQLTKLNLAKNDLQKLPDNFGEMKQLTYLDVHANQLKTLPLSMGGMYNLSYLNISENPFRAPISTLLEKQMKDNHEKDAFPVLITEFLRGLQKELPHDRSKENLWTRRRRKTISFQGDSEKNIETNQKTGTKASQRKLELTLRDFDNKVSRCPATGSDIHKRSSHVWESVGITTTVVIMIPLLLAVAIDSAFLDNLTQDTVTPATIWSKYKPYHCFLQRLVNWCNPQRALITRGPTPAPMLHDFGLLSVIRNYFKAMFNYIMVVPQQQRNTFFIFYPAFVQLPIFFTMVIIEEMYANPPVPESLLERIKQQTNSVLDLSLCNLIQVPLGAIQETRQQYKKLEGFDLSYNSIRYLSPDFAIDMVNLLETLPISMGKMTHLKYLSISDNPFRAPLCNIFCPGAFGQEISGFAQADLVIKFLAEMSTEITAAGDNSQESFLRRRNSQVHYNERSMTGLEYETDEVLSNASHSSNELAVELDEENNLKISHSQPTTNSRKNERKSAMSKRSKYKSENLTCSSNYSCRSKAIDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL20</accession>
    <name>A0A1D2NL20_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL20"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="526" mass="58440" checksum="EA8D2C4814DF0EFC" modified="2016-11-30" version="1">MENKPQFPLPVMPRMGRRNAIAFPDIHNTLSSDAAFSPVNLMQRASTEDYNSLDPDGVLAKQLKQERLRRLTSNGETLTDSPIPLSSMNDTLNNGWTKLLEASNNYNKFVDGLGIFDNKDSTKVQEKLDVLATKQLQIKQAANVIEGDRFGATRISPIIPWRKPDVIRHITPAEERQKMFESFNNTSFEPTETPPISESKLKKSSKRRSKSKGSQESMASTRSKQAPDPYSYIQPKVDTGMRYRVVEESSQDLRPHRHSSIPETGGNSARRNETKLSVKSAPGSSSSKKKPSVVPAKGATVPKTNKFISHRTIKNQLTAEPPKDNRLPLTIGPRYNHKKAWGLNKDTKNRAELVTDVRTRLYQSTVAAQQKWKFEPKPTSTNTLRSTFLNLQKINSGLTNRRLNPSHLNGPVPKETGTGSGEKRISPILQTIQAPPSPFLMSTLSIPGQVMPIPMNGEPPNSKTQKVDPKAKKGKGNATTKENKPLKVIPALGRAPNKYNNIYIGPYSGSDSEGDLGREVQRPKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMB7</accession>
    <name>A0A1D2NMB7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein axonemal assembly factor 1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Dynein regulatory complex subunit 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_00357</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cilium-specific protein required for cilia structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DRC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMB7"/>
    <dbReference type="STRING" id="48709.A0A1D2NMB7"/>
    <dbReference type="OMA" id="SFMEMMT"/>
    <dbReference type="OrthoDB" id="27917at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF12">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN06359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="634" mass="74436" checksum="B4923ED7DB815FE4" modified="2016-11-30" version="1">MGYDDIGREELKCSDYNQEYIRQRMDGAPVDRNLIIITEPMIINCLNELMPSGDEGKYARMVKLDIKMVTYLKMEYRSISEIANLNQLTNLTKLQLCNNVIKRIQNLDVLVNLVWLDLSFNSIKKIEGLDKLTKLEVLNLHRNFVKTLENLDNNLRLQMFHISTNKLDNLENLRYLRRLIRLRSVALQGNPVAMDPDFIHYFVAYNPHIDLIDHIIVPKTEKDIANVKHKHVDKYAATEDKLVRRASIVEAELEVKQLHKEAFVDGLQEDEFWNLLYETDTEGKVLLQLGDTDDIQVMYKELFRRATNDIFEKGMRAHEQRQNEIRAYHIAISEEIEKVQKPGNDLTEEFVEYGRQTLKDIRLLVSLIEDNERRVQNGLAHELPPEFPEFESHLDSLMRDYVKRLHDIWFMLIHHEMDFNEKMEDVNDILDRSIREIITNWLEQLRGQCGSLREVEQQLNGRLQEALVTYGEFRLSDTNIPEELHHLVSDKDALTNCIQMSHDHHVSVVDGKEDQICQRVKKWQDDFSIGLSVNEYERNKARLNEISHFIDSHYSYLEETRGLLHATSYIPPVRADQECTEQATCQPLTWYEKLKKRLRVREKKFKQSIQPKQSVAPVKKGKMGAVPTRTSFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMD5</accession>
    <name>A0A1D2NMD5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Voltage-dependent calcium channel type A subunit alpha-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">Ocin01_00257</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Membrane</location>
            <topology evidence="1 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NMD5"/>
    <dbReference type="OMA" id="ADHNPHQ"/>
    <dbReference type="OrthoDB" id="431720at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009582">
        <property type="term" value="P:detection of abiotic stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009581">
        <property type="term" value="P:detection of external stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042045">
        <property type="term" value="P:epithelial fluid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016322">
        <property type="term" value="P:neuron remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000007">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000001">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000043">
        <property type="entry name" value="Voltage-dependent L-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000063">
        <property type="entry name" value="Voltage-dependent N-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000059">
        <property type="entry name" value="Voltage-dependent N-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000011">
        <property type="entry name" value="Voltage-dependent N-type calcium channel subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031649">
        <property type="entry name" value="GPHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014873">
        <property type="entry name" value="VDCC_a1su_IQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002077">
        <property type="entry name" value="VDCCAlpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08763">
        <property type="entry name" value="Ca_chan_IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16905">
        <property type="entry name" value="GPHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00167">
        <property type="entry name" value="CACHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM01062">
        <property type="entry name" value="Ca_chan_IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17 19" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 19" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4 19" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14 18" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15" id="KW-0407">Ion channel</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="10 19" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="586"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="662"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="782"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="821"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="854"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="928"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1041"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1120"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1149"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1186"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1281"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="1395"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="22">
        <location>
            <begin position="1436"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="640"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1012"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="18">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="23">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00069462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR602077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR602077-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ODN06424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1605" mass="183431" checksum="433F14970DBF06AA" modified="2016-11-30" version="1" fragment="single">GARGANPGGDDLPGPSSLFVFTDDTKIRRCTRFIIEWPPFEYAVLLTIIANCIVLALEEHLPEGDKTILAQKLESTEPYFLAIFCVEASLKILALGFALHSGAYLRNIWNLMDFIVVVTGFITLFAQGNIGVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYCGVLHRTCYSLENLEEIVKEGELPTPCNSDDPGKAPGGAYVCNANSSMCQDKWIGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAYNWIYFVPLIVLGSFFMLNLVLGVLSGEFAKERERVENRQAFLKLRRQQQLERELNGYVEWICKAEEVILAEERTSEEEKMRIMEARRRAAAKRKKLKALGKSRSTDTEEEDEAEDVDDAKKRTGSRSRETFGFRLIGVLGFPRAAYLKSKVKNQGACRRFWRAEKRFRFWIRHTVKQQWFYWSVIVLVFLNTACVAAEHYNQPQWLTDFNYYAEYGFLGLFIFEMLIKVYALGPRIYFESSFNRFDSVVISGSIFEPESSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLSSMRSIISLLFLLFLFILIFALLGMQLFGGAFNLPEGTPPTNFDSFPIALLTVFQILTGEDWNEVMYQGIQSQGGYRSGMIYSLYFIILVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQQEENEVISSAHSLSLNLTGLFKNFIDTLAVEKKGDSKPDDGAKEEEEEPTGPKPMLPYSSMFILSPTNPIRRAAHWVVNLRYFDLFIMLVISMSSIALAAEDPVVEDSDKNKFLNYLDYAFTGVFTVEMILKVVDLGVVFHPGSYCRDLWNILDAIVVICALIAFFFTQGGAEGEGGTQAVSDLSSKLNTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVFNILIVYILFHFIFAVIAVQLFNGRFQYCTDESRDKKNSCKGEFFVIEGNGPPTLQPREWKVQDFNYDDVIIAMLTLFAVQTGEGWPQILQNSMAATWENIGPQPHYRIEMSLFYVVYFVVFPFFFVNIFVALIIITFQEQGEAELQDGDIDKNQKSCIDFAISARPLERYMPKDRDSMKYKIWRMVASTPFEYFIMMLIVLNTLLLMMKYHRQSETYQYILHYMNSAFTALFFVECLMKIVAFGFKYHRSPEQYEDILTYVNLALTMLFSIECVLKILAYGIKNFFKDPWNVFDFITVIGSIIDALAMEFAQNFINLAFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNLKFDPDLSINRHNNFQSFFAALLLLFRYSWTLKLQSLGITTFAISNKASCYFSGHCATGESWPSIMLSCIKDRPCDPLSKKDEDSCGSNLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFIRIWAEYDPSATGFIHFTEMYDMLRNMDPPLGFGNKCPYRLAYKKLIRMNMPLDEKGQVQFTTTLFALIRENLSIKMRPAEEMDAADRELRETIKHIWPLQAKKTLDFVVPPPNEKGKMRMTVGKVYSGLLILENWKTTKFGKIQPPGVPVSFLLRLSPSIILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMS5</accession>
    <name>A0A1D2NMS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-activated chloride channel regulator 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMS5"/>
    <dbReference type="STRING" id="48709.A0A1D2NMS5"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="569" mass="63763" checksum="04C1A5F2094A4100" modified="2016-11-30" version="1" fragment="single">GVTLSAAVSLDEDGYYDIVIAVNEKTEQHGNELEYLERLKSSVQNLSNILFEATQGKFSIRSADILLPDHWQVDADAFATSQHYHNADIRISHEFLMPETINPTLCGYPGRFIELPLNFFNKSESNRIDVKALLTLWARYRWGVHEEHGYPGDSEFPYFWKPYRLPDQPETEPEDWRVTNCANAEVTGNYQNLDGENCGVSDDSLYPPSSDCRFIPDEANQTATSSLMGFHFIESIHDFCDSETHNKRAPTRQNLYCRFLSVWEIIRESLDFKKVKVNATNSIAPINYRILKQTSKPLLYILSDGVFTPPESVIAGVATGLYSIINNTENVNLLATTTVFPSLNRTDSFDALYPLNFPSTEPEKFIDFFKNGFGTRSGFRTFAAAIQDIGNELKERRHKAGAVILVLKYGGDYDYFLPAYESEVLGTILEQNIKVFALEGRDDYVIEPALQRLTQLSGGSHFTIGTGEDDETNVASIMSAIDLTLKAGAVPPSAIELYVAHKGTILYNPENTGTPIPISVLYSNVKKVSFFLSLLNTALSSNFTITKGPDSLDQLPSFVETYIWGKSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M154</accession>
    <name>A0A1D2M154_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Krueppel-like factor 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_19995</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007632">
        <property type="protein sequence ID" value="ODM86687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M154"/>
    <dbReference type="STRING" id="48709.A0A1D2M154"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000032">
        <property type="entry name" value="Krueppel-like factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="237"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM86687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="315" mass="36368" checksum="F0B203D1473B00EA" modified="2016-11-30" version="1">MSRADCDYYTQSTVAFRVHMRRVHNSVTGIPGHFKCLTCQENFPSARTLRRHANVHRETAQTRFKCGKCPQSFDNKSKLKSHTYHLHRQSQRRKLCRKTQHSTSSPFDSYLRERNQQLLGRNNASCKVAKKPTGHFSLQTKTIGAGSNSLVPPKEAIKANQLIENPTSNDKNPQVRNNTSVSNQRKESFRCDFEGCSRSFTRRYNLQSHYRTHTGEKPYLCWWPGCTSKFAKSENRRGHYEHTRNNPQVKLIKHPQFKSKKVSQEKTSGGSDDVNRRERRKDASDAVLRNSSLAGSVPLTYYTQQRTMHHKGDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M178</accession>
    <name>A0A1D2M178_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19965</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007502">
        <property type="protein sequence ID" value="ODM86717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M178"/>
    <dbReference type="STRING" id="48709.A0A1D2M178"/>
    <dbReference type="OrthoDB" id="10044938at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF119">
        <property type="entry name" value="NUCLEAR RNA-BINDING PROTEIN SART-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="86"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM86717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="20672" checksum="ED17D7AF664BF137" modified="2016-11-30" version="1">MIDDTEACSDLTNCEQLDKTEEAEVTKKDMTTPAEVTEPDSVACDTTAEPDPTTCEISYPLATGSVSEGNLGRTSINGSKNKFGNRKLYVGNVSNEVTEDGLREFFSENGLDEDVIVKVILRNGYAFVECRDSEIATVAVEKCNAKTFMNTVLRVEPAERPEFRPRMASRQRSTSQLLVKNCKNVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1G3</accession>
    <name>A0A1D2M1G3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007257">
        <property type="protein sequence ID" value="ODM86792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1G3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="270" mass="29920" checksum="010F065DECBB37C9" modified="2016-11-30" version="1">MFREFPTFGLTKSLPISTRAFSKPRSNTTLSSENVLQRDPPNLNSIIPDPAVISQQIQSSFQSLLQALNNIGNSSDIFSSLRNLTSSIGIGGLRIDDADYILGNVSEALRIANRSALDASNSSGLQGAFRDFKEVVTRLRSSPLLPTQINAERRAYDAHNNNLEGHALTVNNRNANITSGAKQDGLRRMWDQLSTFQAQVDSSIQQTLSNARSNVEGSLSMARQQGTQFMRNQTMGFMTEVRRALKVFTEPFRKFFDDMRGKLPTTVVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Z7</accession>
    <name>A0A1D2M1Z7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_19692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006526">
        <property type="protein sequence ID" value="ODM86990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Z7"/>
    <dbReference type="STRING" id="48709.A0A1D2M1Z7"/>
    <dbReference type="OMA" id="FAYINQF"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="85"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="166"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM86990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="34481" checksum="0E8B98B8A6A77FA5" modified="2016-11-30" version="1" fragment="single">LNIELEENVPQERTEVEECSPQENQKTETNRFLGQGLALASAFSTPECSCHKVTGLPSFQLGCLAIWRDDCCHDPNFALRGLQAVVGANSILLVFFSLKYLNIGDSTVIGTSATVFVTFVACLFLGESCGFVSVLTSLLAVVGVGILSKPSILTGAKELSNDTIIGIAASVSSMLLLTVHFVTLRHLRTMHHALVNFCFVFWGLVESVLVAISMDVFHPSQDFKEIGLIIATAFLALSCITLALKYEQAGTVALVRTIEVVFAFVWQAVILGSQPDIFSVVGAFLVISGVVIMSLRNILMSLPQDHKYRSTFRFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3N6</accession>
    <name>A0A1D2M3N6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 4C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_19160</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005115">
        <property type="protein sequence ID" value="ODM87521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3N6"/>
    <dbReference type="STRING" id="48709.A0A1D2M3N6"/>
    <dbReference type="OMA" id="FANMSTF"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM87521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="346" mass="40113" checksum="4544C21C5E60D3D7" modified="2016-11-30" version="1">MEGNKAFDIHQVITHCALDIICETAMGRKVFVQQKSDSEYCKAIYKLSEFVVYRQLRPWFHPGWIWRLSSAGRENQKCLKIVHEFTDLVIRERKQERIEMLKESKHNESKEEDGVYMNSKKKLAFLDLLLDAQQTDATLTDKNIREETDTFMFEGHDTTSAAASWTTFLLSLHPEYQAKVHQELDDIFGSDRTREVTLADLAKMKYLECCIKEGLRLFPSVPFIGRKLTQEQVLDDGVVLPQGITVLCLIYFLHRDFKVFPNPEQFDPARFTHEKEGRSPFAYVPFSAGPRNCIGQKFAMMEEKVLISTIFRNFRVHAAERLEDVGVLCELVTRPEAGLHVKLEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3V9</accession>
    <name>A0A1D2M3V9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004927">
        <property type="protein sequence ID" value="ODM87636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3V9"/>
    <dbReference type="STRING" id="48709.A0A1D2M3V9"/>
    <dbReference type="OMA" id="VWIEHEL"/>
    <dbReference type="OrthoDB" id="361029at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18086">
        <property type="entry name" value="HsC9orf114-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003750">
        <property type="entry name" value="Put_MeTrfase-C9orf114-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150">
        <property type="entry name" value="CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150:SF13">
        <property type="entry name" value="METHYLTRANSFERASE C9ORF114-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02598">
        <property type="entry name" value="Methyltrn_RNA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="24803" checksum="AADFC88CBBC83F48" modified="2016-11-30" version="1">MSSVPPKLLFPIHPDLQFAGLIAPFDAPHHLRRTEALPYREGVVSSKPIKEGSLVNVGLDRDCRVSKKLPQGVRVTVKFDDPDTNYVLKPKGKLRGTVVSPHLPRREAGLYWGYSVRIANSLSKVFSECPFRNGYDVKVGTSEKGSDSRLLKPQSFDHLLIVFGGVEGLEYALENDESLAEDDVRKLFEHYVNTCPSQGSRTIRTEEAILISMNALSQFIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M538</accession>
    <name>A0A1D2M538_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Piwi-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004117">
        <property type="protein sequence ID" value="ODM88100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M538"/>
    <dbReference type="STRING" id="48709.A0A1D2M538"/>
    <dbReference type="OrthoDB" id="445936at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034587">
        <property type="term" value="P:piRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="1">
        <location>
            <begin position="259"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="454" mass="51235" checksum="2CDDE1EC7AADFF52" modified="2016-11-30" version="1">MNYQRLGRHCFDPLQNVAFPVWRLWLGFNNSIRQQELAIMMNVESCWKVLQTESVFLMAIRQQPPNNFQQACDAAIVGLVVITNNDKQPMLVSKPKLLGQVGDIYLVPELCFPFGLIDDLVQRLARWGRAIVVTGSAKPGFPCGLHDNLRSNFRLMKDLAGCLYMSPNGGVARWRDFLLERGRMLKSAHFEFIQASIKSWNIQLSPKPVELTGRKLLPEEIVCGNSQVTRLDDKADWTNAFRSKSEDDGGSKIGMVGDIVPFDIHHAGPGGGGMSIGAMTATFNESLGRCYSTVPRLSSREEVATAVGAIFEKCLNAYFNKNNRLPERIMMYRDGVGEGQLNAVFNQELEGFQNRIKATYQHQGVKPPKLTYIVVNKRISTRFFEVAGRNINNPRPGFIVDDVVTRPERFSDMRQTLSYYDWTGTVAVPGPCRTRTKLDCFRLAHKLALLWELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5Z4</accession>
    <name>A0A1D2M5Z4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxygen-dependent choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_18348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003749">
        <property type="protein sequence ID" value="ODM88334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5Z4"/>
    <dbReference type="STRING" id="48709.A0A1D2M5Z4"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM88334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="428" mass="47351" checksum="D0617C0F9061A0B7" modified="2016-11-30" version="1" fragment="single">FYDFQPIFVVGGGTAGCVMARKLSDSGEHSVLVLEAGILPDPGLDVPALASSFLSNSNYTRTYYSVPQQNADLENDNDIQGRENAGRTETYNGVFPATDQHGYDGPINVSLPKYVPLLNEWLSAGQFLGYPISDPNGPQQISFCPSEYSKRRGRRVSSYAGYLKPVLGQRKNLKVILKAEARRIIFNGNQAIGVQFRSTTDGFPTDNVVFARNEIIKSAGAVETPALLMKSGIGPTQVLNAASVLDPIRPVKCLPVGQNLQESAAFIEERDLNLQTFRYLNEVGDGPYAAYSGFGGQAFISTTAQGNQTKVRDIQLFHFVAPCVPYCIQIDQIFKQLLGKWQPLHLFSSLMFSGMEITMKIFENTPQFKKLGARFPPNQFPDCERLQFRSRRYWECHAKQSATSFMHASGTCHMRSGEQDPSAVVITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6D3</accession>
    <name>A0A1D2M6D3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003556">
        <property type="protein sequence ID" value="ODM88472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6D3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903535" evidence="1">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="16987" checksum="6E79F58B29099334" modified="2016-11-30" version="1">MKAFYFVLSVAVLAGFANAGEEHPIRLVMTVWERTGTTFIAYDIVTRDSSVVRGISISEGLVPTGDRTCEMIKRQTCVRSSRRSCEVGPTLHYVLSFPTVITEPLKLNLASLCISERPSSTTKRHLHQRVMIPDRLLLRIQTKVICAIPKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6G7</accession>
    <name>A0A1D2M6G7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18119</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003424">
        <property type="protein sequence ID" value="ODM88563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6G7"/>
    <dbReference type="STRING" id="48709.A0A1D2M6G7"/>
    <dbReference type="OMA" id="YANYARH"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="65"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="8">
        <location>
            <begin position="412"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM88563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="576" mass="63631" checksum="5F8BB46BE68A0311" modified="2016-11-30" version="1">MNLSVEQLRMILRTSFPIPIAFLIGIPSLIGYFGIFLQWSDYSSDKLNRTPASAYDFVVVITIFLPVGGGSAGCVVAARLSENPEVSVLLLEAGGNPNPISFVPLAVPFLQNHPATDWQYKIVPLKTSENPPVYQPLSWPRGKGLGGSSTTNFMIYMRGNPKDFDQWANITDDSTWSYANVEKYFNKMEDYHGRYEGLGDNHGKNGPLRIEPLKYSPGLENILAAVKEVGFSVRDLNVNQQEGFSPIDFTQKQGRRHSAYSAYIQPILGRPNLKILRYSHVTKIKPLVNLPVGKNLADHVLTYVGPFIVKKKGNVPVSLMQEDVTFKSLADFVFNGNGPLTSTLGLLAAGVTCSSTSPGWPNLLYLFLSLSIYDGFGATIDRVSGSGNYTKDFLQPFIGNDAHFVALSPGKPKSRGFIELLDNNPFSKPIINPQYYSDSGNQDIQDMIEGYETIVNLYENTNALGNKLGARLVKIPSCSRFEFKTRSYYECAIRTAIRTLFHPVGTNSMGKIGDPHAVVDSQLREISRHYRVLGTRGLRVIDASIMPEITNANTNAPTIMIGEVGADLIKRAFHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6M3</accession>
    <name>A0A1D2M6M3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidylglycine alpha-hydroxylating monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18057</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003371">
        <property type="protein sequence ID" value="ODM88625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6M3"/>
    <dbReference type="OrthoDB" id="10044505at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016715">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680:SF14">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903552" evidence="4">
        <location>
            <begin position="26"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase N-terminal" evidence="5">
        <location>
            <begin position="74"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase C-terminal" evidence="6">
        <location>
            <begin position="217"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="380" mass="42366" checksum="F37D7F91573BC129" modified="2016-11-30" version="1">MVSTLYQCIALTLLNIIIFPNEIVAASVPTDMSILIPYAKPDKPDSYMCTLLSVVSSSRLYIGEQCQLKSFHKLKIPSTKSHQMSLTVKFKPIADMGSVHHMLLYGCKSPGITNKQMWNCGSMGSDGKDIHYRGQRLLLGGICSEGQQRILYAWAKNAPNLSLPEGVAFEISGDTGINSLVLQLHFGDPHHMPTNWNLANGQIGLTLEVTRQKHEKLAGVYVLVTGGSIKPKSTTFLETACVMEEHKTIYPFAFRTHSHSLGKVISGYRVRVNEAGNCNWSLIGKKDPQLPQMFYPVELSVPVTNGDILAARCTMESDRDTVTYIGSTRNDEMCNFYIMYYVTDGKILEKNVCFFGWPYENYWKNASPSLNNIPKDASTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8G2</accession>
    <name>A0A1D2M8G2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c oxidase assembly protein COX15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_17410</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2</text>
            <dbReference type="Rhea" id="RHEA:63388"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:61715"/>
            <dbReference type="EC" id="1.17.99.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:63389"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002759">
        <property type="protein sequence ID" value="ODM89273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8G2"/>
    <dbReference type="STRING" id="48709.A0A1D2M8G2"/>
    <dbReference type="OMA" id="AFVCYSW"/>
    <dbReference type="OrthoDB" id="1726137at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120547">
        <property type="term" value="F:heme A synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023754">
        <property type="entry name" value="HemeA_Synthase_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM89273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="33942" checksum="1FF431A3BCFB372B" modified="2016-11-30" version="1">MVSWKLFGEKPPLSETDWEVEFKRYQEYPEFKIKNKDISLDDFKTIWRMEYLHRMWGRGIGAVFYIPAGIMWYKGFFSKVMKRRVVILGALLAFQGLLGWYMVKSGLEDRFHGESDTPRVSQYRLAAHLGSAFVLYSLFLSTALGKLAPPQTFERTEAILRFRKVAHCAKGLVFLTAISGAFVAGLDAGLVYNSFPKMADKWIPDDILALDPAWKNFTENPTTVQFDHRILGITTFSTIMGLWALSRKTRLPRRATLAANLLAVVAIAQVTLGITTLLNYVPTHLQPHTRVDRWCSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8J2</accession>
    <name>A0A1D2M8J2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002774">
        <property type="protein sequence ID" value="ODM89252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8J2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="353" mass="38846" checksum="B3185C3BF871AF50" modified="2016-11-30" version="1">MVVAVREVIGRAATAWREALLHLLSFISIHQRQQQQNPSRPPFSIESDVYGLYGNLINVRGLEDEGRFVDPLYDALRRSDPELNALDAKIIDSKISASSDESVGLGSRSSQQTTDSNAPTAIVGNNISPLPPNGEVGDGGSNADAGKKHSITTAGIMPTLPPQRKQCQGKSTKVSYGVFFPSICIRTSITHLTFGGSGEILFQLWPSRSILNPLFVDYFSSQVLRFIGGRRDFRVYDQFDKSRRRVDSSAFSVFYIYAYLILHLGRISSGHCVLECIIQGDPQSAHFPILQPSFEGNIIFGALLRRTTRVLLLYAVDGDEAEGDGSNALSMLLQLDLSLPALPYYIYMTTYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M913</accession>
    <name>A0A1D2M913_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002675">
        <property type="protein sequence ID" value="ODM89394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M913"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="128" mass="13599" checksum="23D24FDCA83BBF84" modified="2016-11-30" version="1">MTATSNGIMNDWRNGNGIPVYQHFSAPSTTFVNIFRQPGVYNITIALPGSVGRMNPTITAPPSGIPSRQPGMTLGSHNQPNFGGAPSMTRPKLSPRRSNSADHMPGTPVQGTDLPSQLEFGLPKCHGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M962</accession>
    <name>A0A1D2M962_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methyl farnesoate epoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_17184</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002590">
        <property type="protein sequence ID" value="ODM89500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M962"/>
    <dbReference type="STRING" id="48709.A0A1D2M962"/>
    <dbReference type="OMA" id="ENGNDHM"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000036">
        <property type="entry name" value="CYtochrome P450 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF376">
        <property type="entry name" value="CYTOCHROME P450 15A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903665" evidence="10">
        <location>
            <begin position="26"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM89500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="493" mass="56483" checksum="16915614E4B76533" modified="2016-11-30" version="1">MILELVLVVAVISLLLYLFNENCRPSKFPPGVWRLPVIGSLPFLKMPLHEHFTTLSKKYGKIFSLYIGNFPTVVISDANMIREAFKLDALNGRPDSRVFTERSWGKKRGIIFNEGKDWTEQRRFALKNLRDFGFGKGTMEQLILDEVCSFREYLKKFTGSPVSLNREFNLPVLNALWHLIAGERFSFDDQRLRAIIKKLVDNFKAADAGGAIFFFPWFTKLAPKLSGWEAFFSVLKPTMTFLSEPVDEHRKTFNPDNLRDLIDVYLNEISKTTDKTSGFYKDDGDKTIKTVMLDLFVAGAETVSTTLNYSLLYLINFPEVQEKLQKEIATNIGSKLPSLSDRPKMQYLEAFIAETLRYSSFVPNGVFHCALETVEFNGYVIPKGTNIFPNLWQVHFDEAVWGDPKNFRPDRFIDENGHYKKNDNLMPFSVGKRVCLGESLARDEIFLFLTSLLQKFSFEPEVKGSPPSMEASKQGGLILQPQEYKVVLKERTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M985</accession>
    <name>A0A1D2M985_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002553">
        <property type="protein sequence ID" value="ODM89543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M985"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="345" mass="38524" checksum="870521882F88675C" modified="2016-11-30" version="1">MGPRSKIKKTRNTIMKSTKGKSSYYLYAVLGICIACLPFLVVSAQVDEEQVAEASDSMMESDLDVAESQHLGVAPQVVSVPTIPIPAVVPAPANVVPAASFAIPKTDLASAPSYAPRYSVPPVNPYRERLPYEVQNFRRRATEDEDAQPAEDDYQPSESKGKKSSPSVFKRVRNGIRNTGKAIVGAPSYIYKRYRGTWKKYFGGGGKKKKGGWKAWSPSEKTDGGWGGWEESEPSGGGWEGSSYPTEKGWKSSKGYGPPKGFDSNERRSDREPPRERDSDYYDRPARERTERPRDRQRWASNYKEETHYDDYDGRRTVATNGPSRKSPKRPSSGGSGNYRYDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA82</accession>
    <name>A0A1D2MA82_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_16805</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002310">
        <property type="protein sequence ID" value="ODM89880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA82"/>
    <dbReference type="STRING" id="48709.A0A1D2MA82"/>
    <dbReference type="OrthoDB" id="9831996at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000012">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM89880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="143" mass="16010" checksum="9746AB3E65E07D08" modified="2016-11-30" version="1">MTGRGKGGKGLGKGVAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKPSLPWTLSMLSSVKEELSTVLEVKQSIAASTLRIFECADNPKALLRATKTYKEQTLQITMKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAL7</accession>
    <name>A0A1D2MAL7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DBH-like monooxygenase protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16646</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002223">
        <property type="protein sequence ID" value="ODM90036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAL7"/>
    <dbReference type="STRING" id="48709.A0A1D2MAL7"/>
    <dbReference type="OMA" id="RLVHHIV"/>
    <dbReference type="OrthoDB" id="10003276at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042420">
        <property type="term" value="P:dopamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.230:FF:000001">
        <property type="entry name" value="Monooxygenase, DBH-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903728" evidence="4">
        <location>
            <begin position="20"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="5">
        <location>
            <begin position="43"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="466" mass="52217" checksum="20490053E15B2C9E" modified="2016-11-30" version="1">MIFTVIITLLVAALTHTECKVTNPNVQQDSTIRSGEEYLDSEQSYLLKWNVSLTEKRIYFEVTANTTGYIGFGISPTGGMAGADIFIAGVHPNGTEYSSDATVRVIYAMGETDDLVFHGPNKGTKSINFFLEDASFDSEGYDSFDLIAKSEMPAQDTTYWCTLHKVPAFSEKQHVVAFEPVLKGSLALAHTHHFTLFKCVVPDNINADELFGPFVESGEGHHCFENPNNFPTSYCREQAVYGWSKGGKWTIFPSNVGYPVPDKLNRNEYYSIETHFDNPRNLSGLVIESGIRAHYTKELREHDAGLLIVNHDTSPVLTIPPNSKNFIVSGHCSSACTENELPEDGVTNFNNLFHSHLAGRKMKLRHFRGNNELSWVDVDDQYDFNYQQNKPLSTYVKVERGDQLTVECTYDISKNLDDKIVVGGLSTREEMCEAVLWYWPKTELIVCGSSKNSPAISSNWSNKSCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAR0</accession>
    <name>A0A1D2MAR0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent RNA helicase SUV3 homolog, mitochondrial</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_16663</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01002234">
        <property type="protein sequence ID" value="ODM90019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAR0"/>
    <dbReference type="STRING" id="48709.A0A1D2MAR0"/>
    <dbReference type="OMA" id="QPANWYT"/>
    <dbReference type="OrthoDB" id="6692397at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17913">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1080:FF:000001">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000269">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000446">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041082">
        <property type="entry name" value="Suv3_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044774">
        <property type="entry name" value="Suv3_DEXQc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041453">
        <property type="entry name" value="Suv3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18147">
        <property type="entry name" value="Suv3_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18114">
        <property type="entry name" value="Suv3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="345"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00069703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM90019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="724" mass="81697" checksum="A85D0FF0D5EB1F7F" modified="2016-11-30" version="1">MHRSTSLAARMVTFTSWNVLRNTACSSNFSLQHIQVRFKKRSAKPLPEITGSPTKTNTQNNGVSHLFVPVPVKATGEDGTVGIELAGKLRKQDILQVLNKFFRRSEVKLLSAEHGLDNYLFHQAFISFRKLCLDADTLPVDLHIIFSDISHGAAHVDDLFAYFVKHAKQIFPHLECMDDLKKISDLRSPANWYPEARVSPRKIVFHAGPTNSGKTYHALNRFFEAKSGVYCGPLKLLASEVFQKANEKGTTCDLVTGEERRFGNPDQSAASHVACTVEMTSVVNQYEVAIIDEIQMLRDQQRGWAWTRALLGVCADEVHLCGEAAAIELIKNIMITTGEDVEVHKYERLTQLEMERAALGSLSNVRPGDCIVCFSKNDIYRVSREIEGLGHEVAVIYGSLPPTTKLAQAKKFNDPDNPCKILVATDAIGMGLNLSIRRVIFYSLVKPTLNEKGERERDVISTSQALQISGRAGRYGTQFAHGYVTTFKNEDLPTLEKLLAAAPEPLEQAGLHPTADQIEMYAYHLPSSTLSNLMDIFVNLCTVDDSLYFMCNIDDFKFLADMIQHVPLPLRARYVFCCAPLNRKMPFVCTMFLKFSRQYSRNKPITYDWLCEHIGWPFNAPQTILDLVHLESVFDVMDLYLWLSYRFQDLFPDPSMVRETQSELDSIIQMGVFNITKLVKKSVESNTTSTSFDDGEITLHKKQKHIRGRRMGYKKDTPNPTSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB22</accession>
    <name>A0A1D2MB22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/arginine-rich splicing factor 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16479</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002116">
        <property type="protein sequence ID" value="ODM90198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB22"/>
    <dbReference type="STRING" id="48709.A0A1D2MB22"/>
    <dbReference type="OMA" id="DYERPCL"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM90198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="153" mass="17014" checksum="12F09C6E70A282DF" modified="2016-11-30" version="1">MPPKERRLYVGNLPYDIREKDIEDLFHKYGKIVDLKLKIPRGGNPFCFLEFESPKDAEDALRRRNNYVVGGSKIRVEYPTGNGPRGRGGRPVGGSGGGGGGGRRGGAAFSRSEFRVRVTESMDNSMDYERPCLNQKGCRVVGLAAHHLYGWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBI5</accession>
    <name>A0A1D2MBI5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kaptin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002009">
        <property type="protein sequence ID" value="ODM90367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBI5"/>
    <dbReference type="STRING" id="48709.A0A1D2MBI5"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030027">
        <property type="term" value="C:lamellipodium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029982">
        <property type="entry name" value="Kptn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15435">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN KAPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15435:SF2">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN KAPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="30194" checksum="1212F833A4449937" modified="2016-11-30" version="1" fragment="single">LESGRWIKKLHATKVERPIGGAEGTARGGAGVNGKLLIWIVTCKPQSKMQGSMTESTASTATSKSRMSPQPDVETSISPQDSPTEEFIDKLSDDSKGLGADGDTSSMSDSYDTTLSSSDENFERIEHTYDGLITAIQSYVDGFELNVIVSSALSPTYVYTNSYEDSFKSGTPLKFSSRWDTVQACCVADIDMDGRAEIILGTFGQALLVYKYMDEILPQWVIVSKKQFSRGILGIEFINNYLHVVTALGIHILEYNTAAYFTNKPSVTSDSFELGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBI9</accession>
    <name>A0A1D2MBI9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_16399</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SINA (Seven in absentia) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01002057">
        <property type="protein sequence ID" value="ODM90282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBI9"/>
    <dbReference type="STRING" id="48709.A0A1D2MBI9"/>
    <dbReference type="OrthoDB" id="4788989at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052088">
        <property type="entry name" value="E3_ubiquitin-ligase_SINA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049548">
        <property type="entry name" value="Sina-like_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013010">
        <property type="entry name" value="Znf_SIAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10315">
        <property type="entry name" value="E3 UBIQUITIN PROTEIN LIGASE SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10315:SF71">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21362">
        <property type="entry name" value="Sina_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51081">
        <property type="entry name" value="ZF_SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="7"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="SIAH-type" evidence="12">
        <location>
            <begin position="63"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM90282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="253" mass="27954" checksum="281F7004F0C81F19" modified="2016-11-30" version="1">MEKFRSCPICLEVPEGDIFQCTAGHMICSICITKVERDLCPQCRIPFGTPKIRSRILEEILDSQEFLCGFSDNGCTQLCKRAEVTKHAKSCCHNPDTVSICKQLGFSSCEFQLGSVSRAEVISHFENTHKCPFQKTSGNWGVRLPGDHMMRTLGKKRKEGASKIPNDTVNLLTPPGASETSPLFLFISKINWTALSVSFAVVKVWETPSLPPVKYDAKFVFHKKNSTTGSQPGSSSSTIKPIDGVSIISNMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC19</accession>
    <name>A0A1D2MC19_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Valacyclovir hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001974">
        <property type="protein sequence ID" value="ODM90434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC19"/>
    <dbReference type="STRING" id="48709.A0A1D2MC19"/>
    <dbReference type="OMA" id="YGENDII"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331:SF2">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="28111" checksum="052F169D945BBE09" modified="2016-11-30" version="1">MLGSIQMDIKPIIPVLDKKKYRWIGWDAPGHGRSRPPNRPFLPPGYGCGYEYDVKYATELLKILEIDCYTIVSWSGGAITGIRMAHSFPDQVSSLVTWGGWGFVGTAIKNLLKSFQRQGINGIPESRRVELTEMYGEKLLQDMWDGATDEVIAMSETDVYQDGGSFEEVIKNVKCPALVIHGTKDAFFPVSYAHHLNSTFRNSRLHIVKNGTHNLHLRQTDEFVKCIEGFIDSCLHTDQLKLQPNTSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCX3</accession>
    <name>A0A1D2MCX3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001816">
        <property type="protein sequence ID" value="ODM90734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCX3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="57854" checksum="8FAB3D131847C06B" modified="2016-11-30" version="1">MSLTNKKSRSDSPENENSPVPHFTTDDDALVFGQLNDDAQKVEESHHFLIATVPEVWLNVFEKLNPEDKPAFSRACPQFHAWLEPRRNCFLLYEVAPILLEKVSKQILLESRKICRFWSQATDHQYRERRSDPLRLVEDPRPPVYTNRFHSTESMQKFMVEMENHPGNPFPWGNLQFQWNPPDDWRQQPEFDKISHCRTYWTLVLSILRKFGSEVEYCRLIIGDSSILVEEMAEFLRNILPNLPKLKRLAICGGSGQIQNPYRGIKLPLLPKLEVVNARYADWDLISAILNACVPSNVKRLSFENTQLGGRVELPEPVYGFSNLEFLKAPISVRDLQRLGTSTPVPPLKEVDCQFENSRVSFEEVFTALGSFSTSLIHVAASMLAANGEVGTRISLPNLRKLHIRFYQGTFEPILQLKGLTHLKITSCRRLRREDMAREPPINVGEDSVQFYGFERKMYESNIWRLMSSLQTLRIGNDQYERHILNLRNHSCQSQINLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD29</accession>
    <name>A0A1D2MD29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_15821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001765">
        <property type="protein sequence ID" value="ODM90863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD29"/>
    <dbReference type="STRING" id="48709.A0A1D2MD29"/>
    <dbReference type="OMA" id="KCSSWPA"/>
    <dbReference type="OrthoDB" id="5960141at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.570.10:FF:000007">
        <property type="entry name" value="Alkaline nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF19">
        <property type="entry name" value="NUCLEASE EXOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="6">
        <location>
            <begin position="47"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM90863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="308" mass="34822" checksum="56C22BD61973F940" modified="2016-11-30" version="1">MLYVNKNAVNFTQLGCSKQVKEKLVVVGNCYNESTAVDILFQANNTQLPLINICHNTNRDETIYAHHYIIGAGLNPYEVSNNRPSFKEGQFYTTISANDAYSQSSQKNQVAYLVGSQSLAEKYINTSRSFYFARGHLAPDGDFVHIYEQNATYYYINVAPQWQAINNGNWKALESALRTYAKSKNTNLEVWTGGKDVLKLDDVNGNQVEIYLARDSKGKLSLPAPELSWKVLRDPSRNASVAVFMINNPHLTKIPSRLIVCPDVCSQISWVTWDVKNVEKGYTYCCKMDSLKNSLPYLPEMSKEQLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDD3</accession>
    <name>A0A1D2MDD3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/glucose cotransporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15761</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001741">
        <property type="protein sequence ID" value="ODM90922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDD3"/>
    <dbReference type="STRING" id="48709.A0A1D2MDD3"/>
    <dbReference type="OMA" id="TTIGWDT"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005412">
        <property type="term" value="F:D-glucose:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819:SF195">
        <property type="entry name" value="SODIUM_GLUCOSE COTRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00457">
        <property type="entry name" value="NA_SOLUT_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="597"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM90922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="697" mass="76604" checksum="D10EECA079F8F3E7" modified="2016-11-30" version="1">MPLFPIGASDKRPLATFSHPEHAWVPVGASLFASNIGSGHFIGLAGSGAASGIGIAAFELSAIFIILLLGWIFVPVYMAAGVYTMPEYLKLRFGGQRIRVYLATLALILYVFTKISADLYAGALFIQLALGFDGDEGLYVSIVILLAIAALFTIAGGLTAVMWTDFVQTILMLIGASILMILSFNAVGGYDELIRKFMSEANPSENATLYDENNQSCGAVPDDAMHLFRSATPGKSDLPWTGILFGMTISSIWYWCSDQVIVQRVLASKNMVNAKGGCILAGYLKLLPLYLLVFPGMAARVLYTDRVACAKPEVCKAVCGSATGCTNIAYAELVIKLMPPGLSGMMLAVMMAALMSSLTSIFNSSSTIFTIDIWTRFRKNPSDAELLIVGRLSVLVMLAISILWIPILRGMESPQLFVYIQQVSNFLAPPVAGVFCMALFHTRTNEPSICSDVSIIWVPIILAYRESQLFRYIQSITSYLAPPVCAVFFTAVFVNRVNEQGAFWGLMIGLVLGLIRFILEFSFLKPSCGSGELDVRPEWIKWFIDEVHYLHFGCIIFLITLLVTYCVSLVTPPIEPEKLYRLTFWSRHSTLVRKPMEDESDKSNHVAPATTNANGTVKDDEDKAEGALMKVLRCICGSESKAAEQARIEEGPSKLSPEEEAATAAKFLDEKRFWKRFVNSNAMLLMTIAVFVWAYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDF2</accession>
    <name>A0A1D2MDF2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transportin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001713">
        <property type="protein sequence ID" value="ODM90983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDF2"/>
    <dbReference type="STRING" id="48709.A0A1D2MDF2"/>
    <dbReference type="OMA" id="LECITSW"/>
    <dbReference type="OrthoDB" id="435593at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057941">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058537">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF42">
        <property type="entry name" value="TRANSPORTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24138">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24139">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="1">
        <location>
            <begin position="36"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="2">
        <location>
            <begin position="108"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="954" mass="108086" checksum="4BE0E9B7093EC1FD" modified="2016-11-30" version="1">MAAEVQVTELEQVYRAVHTLYNDSNSIPMSDKQAASSWLNDFQRSVKAWEIADQLLHKKMDLYSCYFGAHTLRTKIQGFFHELPLEAHLSLRDSLLQHIAAISSDTDHIIVTQLCLAVAHLILQASTWADPISHLLGTFGSDPSHWWPVVEILTLLPEEVHSRKLHLGENRRHQVNAQLESASPNVLNFLRQCLTVSLGNSAPPGVPTDLLKVSILKCFASWVTSNPDCFCNDRQGEVLRYAVENLRSGKAGQKIHTASTDCICAVIEVVPDIDASSNNNALELQSFQLNLYTSIISFEEAYHYSVAEEDQDKVMNYCRIFTEYGESMIPYMLRSWRDPHYSINIINYILICEGHHDYDVAELTFGFWYRLSEDLYHAHDESLNAVFRSFAQRLVVALYKHCQMEPDHEGPLTSSDEFYEFRRKASELVEDIMFIVNSQQAFQELGQLFIMENSWECKESALFLLYHVARSIDTRDSTVIGPIVEAVLNFTDWRHISLKISAIRFLGGMSAWLAKHPDDVLEKTMNFLVNSLPATECSSTAAAALQNVCQQCADHIAGRYINNLLTIVGQLDTYNVCNDAVVGLLKGVGHVVGTLPRDQLSQIIRQICWAQLHPLNQLCDTDASSPYQKGTKSDPTFWIDRLAALFRNTSVQNSRDGTMVEHPCKPAICEDVWPVISKVLNKYQADSRVMERVCRCVRYAVRCVGRHSHPFLEPLVMQLVALYGAHHHSCFLYLGSILVDEYGEDAQCVEGLLQMLAAFIPPTFAILNEPSGLRNHPDTVDDFFRLCTRFLQRCPIALLKSDILSTLVTYATQATQLDHREANMSVVKFLFDLVHAGRRHNDLACFAERKTLVRNTMMQHGPNLITMLIHGVIFQLPTYTIGDICELLYEIKEMMPKEYASWIENALKQLPENTPAGTQAATLTQLESFHKQATGARSPKELSRSLKDFCRLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDR5</accession>
    <name>A0A1D2MDR5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isoaspartyl peptidase/L-asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Ntn-hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001674">
        <property type="protein sequence ID" value="ODM91089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDR5"/>
    <dbReference type="STRING" id="48709.A0A1D2MDR5"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033345">
        <property type="term" value="P:L-asparagine catabolic process via L-aspartate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF43">
        <property type="entry name" value="ASPARAGINASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="10177" checksum="1B6B2F8FB016A048" modified="2016-11-30" version="1">MTRVQEALRAGYDVLKATNNSVDAVEAAIKVMELDEAFNAGYGSVLTSTGEVEMDAILIRGSDLKAGAVGAMRKNPIRLSFTFGPFSNLNCIEPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDY2</accession>
    <name>A0A1D2MDY2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 4C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001638">
        <property type="protein sequence ID" value="ODM91185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDY2"/>
    <dbReference type="STRING" id="48709.A0A1D2MDY2"/>
    <dbReference type="OMA" id="LFNMFAA"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF201">
        <property type="entry name" value="CYTOCHROME P450, FAMILY 4, SUBFAMILY B, POLYPEPTIDE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="883"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="936" mass="107471" checksum="1337BB7CD9F4BA64" modified="2016-11-30" version="1">MILTTEYGEMVQPFENLQWVLAALCIFLICILKLYEKSTPKNVADRKTSRFENLPGPGHYLWGSYSNIFALRDMKECLKVIRNWCADYGPIFKVRLGPLQYVVLNSPEYIQKLMGSRDMSYFGKGFAYEPFKPFWKDGLIISKGEKWKFRRKVLTKHLFSFKTLLSYMKVFNEEADTLVQTLGEMYADGKEKGIEELLMHSSLNTITKAVLGKNVAEIETMDEGDLSVTETVIKVKDVVSMRVLSPWLLSDFIWRLHPMSKVADFVEKMSWKHITNAMKSTNNNSLGIKKDLMAAGISFEGVLEEGSTLISAGHETTATSLHFLLFCLALHPHHQKLCREEVDSIYEDVDLCSGENIQFRALIKLRHLELCVYEALRLLPTVFLMMRKIEAPLEIEEDLILPSGTEICIFTQGLHMNPEYFPEPNSFIPERFSREESKNRHPHAFIAFSAGPRRCIGQKFAMMEMLTLTAKILRHYDISTSDKLQDVVLLPIITLTPEKPMNFLFTKPCLNVIEGWCRKYGPVFTVNFGPSLPITFLNSPEYIQKLLASTDMGHIGKGFIYEPLKPVWNDGLIISNGEKWKTRRRLLTKHIFSFKSFVAYMKIFQEEADTLIETLGEMFQNGEENEIDDVLLRASFNAVAKAALGKCATEIEVPDETNNFSLFETVKKIKEVVATRVINPWLLFNPIWRLHPLSKVETGLVQNVWKYGHRCISDDENKNALKEDLLAAGVSIEGILEESVTLISAGYETTGISLQFLFFFLALYPEHQEKCRTEVDALFETSEDLQYKSLGKMKHLEMCVNETFRLLPTVFVMMRKIETPLQLETDLEIPGGSQISIFVPGLHKNPQYFPEPDKFIPERFLEKESKARHNYSFVPFSGGTRMCIGYKFAMMEIMSLTSKILRHFVISTNDKYEDLVCLPHVTLTPQKPIKFIFKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-10-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEA2</accession>
    <name>A0A1D2MEA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001588">
        <property type="protein sequence ID" value="ODM91346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEA2"/>
    <dbReference type="STRING" id="48709.A0A1D2MEA2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="1">
        <location>
            <begin position="60"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="188" mass="20844" checksum="8C0D8A2C2EFE959C" modified="2016-11-30" version="1">MTSEALADEHNGELSRFKHLKHGKNWYFERGRSHNCHYGHWRVRGTHEALKDNFVGEYGWFDPSHQHSYTHDNNGHGTHTTGTIAGGKHLELNGPPVVDVLPQLAINPIFSPVETSSLAPLVLMDPAQTAARLPMSFPTPGEVVEEITWYNGVIEGWHAAKIIPLFSNGNSDQAATLPILPLTRTSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF34</accession>
    <name>A0A1D2MF34_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ADP-ribosylation factor-like protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_15065</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001475">
        <property type="protein sequence ID" value="ODM91617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF34"/>
    <dbReference type="STRING" id="48709.A0A1D2MF34"/>
    <dbReference type="OMA" id="EGMEWVC"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051649">
        <property type="term" value="P:establishment of localization in cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000281">
        <property type="entry name" value="ADP-ribosylation factor-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="28"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM91617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="20574" checksum="5A76A2618454276F" modified="2016-11-30" version="1" fragment="single">GLLSLLRKLAVHTSANSGVAQFRILLLGLDNAGKTTLLKMLANETDDHLKTSPTRGFNVKTVQTDGGFRLNVWDVGGQRNIRPYWTNYLENADALIYVIDSADRKRLAEAGEILFDLLEDEKMAGVPLIVFANKQDLADAASTADIARSLNLHTVRDRAWQIQGCSAATGEGVREGVEWVLKAIRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFB1</accession>
    <name>A0A1D2MFB1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine aminopeptidase</fullName>
            <ecNumber evidence="6">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15089</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01001491">
        <property type="protein sequence ID" value="ODM91592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFB1"/>
    <dbReference type="STRING" id="48709.A0A1D2MFB1"/>
    <dbReference type="OMA" id="SSKMYVM"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF8">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="7">
        <location>
            <begin position="126"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="362" mass="40325" checksum="0FA3FB0FA047098A" modified="2016-11-30" version="1">MFKVTTLSCILQRSIKRMTFPAVGVSEGPNRYYFLQRIGCYNSRHFVTTPLMSSKGSDIEGSVDNDEDGYRSLYGAYELVVPQKVSALLKVPSHIQLPNYVPTPDGRPLGPAKKGPFIRTKEELDIMRDTCILTKQILRKTIREVKVGVTTDELDKYAHHLIIENNAYPSSLLYKKFPKSICTSVNNVACHGIPDSRKLLDGDIITIDLMVYKNGFHGDCAETALVGNVDEKGKCLVKTAKQCLDLGINQCGPNVPFEYIGKCIEDYANDLNYSVVGAFAGHGIGRNVHELPEIYHYERPDVKKQLMIPGMTFTVEPVISQGMDLVTLLSDGWTYVTVDGSRAAQFEDMILITNQGFEVLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFE0</accession>
    <name>A0A1D2MFE0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">U2 small nuclear ribonucleoprotein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001447">
        <property type="protein sequence ID" value="ODM91710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFE0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="472" mass="54978" checksum="C141C566EEC5146F" modified="2016-11-30" version="1">MDKFQVKRATVESEDNLNQSNLMESTDYDYFSPALMDCWPQIIDHVKRPQDIQAVMNTSDLFYAMVEPRVFTELIFPVLLHNESYLGKGGILTCRQLSHQIKAQVDYTLNQVPHPWIEDHLDTSEDIEWLMEKAKDLPDFNPFMHRSIETFYDNLDDLKSAVEMFKAFGQYLTSVKFYLPNEYRAGPMMELMIDALKYLPHLQSLRLITTQAEHGEDDRTLLEPIPPSRMPKLNKLFKLQLLSFIDEDGGVGQRPAAFLQSFLNAYGKQVTNFSSNEFLFHFGFDVEFFNVNLSNVEHYKVYNFDDIVAAEHGVLSQVSWPKLTSIDIFSGAISFTPEGLQTILNFRASLTEIRFPHLICEDIDQILETQPDDFPNVKQIILCPSNVGLPVVLRGFPRFFPNLEHIKFLPDYIHLNEPIPELSVRQSFFKSYPKLETFVWSRCVSYSKWMDNEFRRKDVIPFSRVYYTKKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-05-29" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFN2</accession>
    <name>A0A1D2MFN2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001416">
        <property type="protein sequence ID" value="ODM91798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFN2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="63" mass="7213" checksum="F9C2D7492AE725BE" modified="2016-11-30" version="1" fragment="single">FNFELKVYLVPILSTKSQRLLKKHAPCPLGSNDLLSSKRPSLVFVRIDLEFEVVNSIDKDQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG78</accession>
    <name>A0A1D2MG78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Synaptosomal-associated protein 29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14709</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP-25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001364">
        <property type="protein sequence ID" value="ODM91973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG78"/>
    <dbReference type="STRING" id="48709.A0A1D2MG78"/>
    <dbReference type="OrthoDB" id="18679at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031629">
        <property type="term" value="P:synaptic vesicle fusion to presynaptic active zone membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016082">
        <property type="term" value="P:synaptic vesicle priming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15887">
        <property type="entry name" value="SNARE_SNAP29N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000041">
        <property type="entry name" value="Synaptosomal-associated protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM91973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="171" mass="19290" checksum="E95AC7E2136BF947" modified="2016-11-30" version="1">MAGSSYSYDKSTPFFSTEDAATSGGKEEIETRTLESSFRSLSLLHESEQIGNATAEELTRQREQLQNTEHKLDQINSSLRTSQKHIQGIKSVFGSIRNYFSSSTKPETTAIKTSASTSELDKQATPRSKLADILETSAEHPEIQSIQRNDFAQKSSRKARMWMTYWIAIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI50</accession>
    <name>A0A1D2MI50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001192">
        <property type="protein sequence ID" value="ODM92601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI50"/>
    <dbReference type="STRING" id="48709.A0A1D2MI50"/>
    <dbReference type="OrthoDB" id="6067523at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000538">
        <property type="entry name" value="zinc finger protein 853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050752">
        <property type="entry name" value="C2H2-ZF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24384">
        <property type="entry name" value="FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24384:SF196">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM92601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="535" mass="61594" checksum="6B728CDE148A6C67" modified="2016-11-30" version="1">MEAMSRGKDLTSKGRQEGQQRRIFRCTECPYQSVYKCSVQVHMRYMHGAEKRPKAIKKFKCPECPKRFPNLSRMKQHFSLRHKGEMPYSCVFCEKKFGFRSSFYRHLQAHIREFYYSCTICDYSSTSNESLKSHIRHIHEGLTEEERRKTLKVCPVCKKLVSGLNHHLRKHTGERPHHCGKCGKSYKDSSNLKDHQLIVHEGQKPHCCEVCKAKFGRVGDLKEHLRYVHGPEKKPFVKRMHNCVFCDKNITSGSRYSHYRRHIKEYSYSCPNCDKSYASAGELKRHVDIHHYFKVPVKKLVECNICNKSLFSKQSLAKHMCGHTAGKPIFLCNLLLSLLFLERCGLDVHMRRVHGTEKHPKSVLKIKCSECEKWFSCRGRLRVHFRRHTGERPYSCLFCESRFLDTRSFNRHLRSHIREFYNHCKICGNSFNGRSDLKAHVKRKHFILAALATAKDCDRKRRQSVNTDSGNVGGVHETTNNNVNPLGGLGDALKGLPPSANGKAPVIEIASVNTIVGEGAPTGGKSECKDKDDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MII8</accession>
    <name>A0A1D2MII8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA topoisomerase 2-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001147">
        <property type="protein sequence ID" value="ODM92799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MII8"/>
    <dbReference type="STRING" id="48709.A0A1D2MII8"/>
    <dbReference type="OrthoDB" id="6426401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="54"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25221" checksum="8A80C29F6185FC28" modified="2016-11-30" version="1">MIKKKPCARKSTGGYYPIRFPLVSVVNTSEFPAGGTSSSGPLLFPLELPENPKFMLSREKMSNLHQDIAEDIINDLGGSIIDKEDEFDPDAVALIADRLGSSEKVVCSIAAGIPILKMRYLEKSAKARRFIRVKQRHVWQEADVKPTEREERKLVRASYNWLIAQRQDGKKGVMFGKKFFLLPAPQSRMETSRRMIEAAGVSWWMIEKTQPLSSRIRRLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ71</accession>
    <name>A0A1D2MJ71_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTP-binding protein RAD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001101">
        <property type="protein sequence ID" value="ODM93003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ71"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ71"/>
    <dbReference type="OMA" id="MACTHKI"/>
    <dbReference type="OrthoDB" id="5239715at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005246">
        <property type="term" value="F:calcium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051641">
        <property type="entry name" value="RGK_GTP-binding_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45775">
        <property type="entry name" value="RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45775:SF6">
        <property type="entry name" value="RAD, GEM_KIR FAMILY MEMBER 2, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11409" checksum="C6CAABB44380E75A" modified="2016-11-30" version="1">MPRLFPEGKQLATNHDSKFIETSSGIQHNVDELLVGVLKQIRLREAASIPQALPKAHNRSHSHVQGTTPRGSIMSLLFTRELINKLCFLTNKAKSCENLHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJD2</accession>
    <name>A0A1D2MJD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fasciculation and elongation protein zeta-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zygin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001056">
        <property type="protein sequence ID" value="ODM93166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJD2"/>
    <dbReference type="STRING" id="48709.A0A1D2MJD2"/>
    <dbReference type="OMA" id="CFRDYGT"/>
    <dbReference type="OrthoDB" id="7959977at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011680">
        <property type="entry name" value="FEZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12394:SF12">
        <property type="entry name" value="LD08195P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12394">
        <property type="entry name" value="ZYGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07763">
        <property type="entry name" value="FEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="29931" checksum="ABB991CEC7F8E0F4" modified="2016-11-30" version="1">MRDCRMWWTITGNYGNILPIDWSKTYARKLQIPALNLNEQVKAEEEEYTSLSDEDEAVASDLDMHSLILGRSHETEPEPPTADEVIKEIDFIMQDSPASECCCDESGACNCQERCEKGKHCSAPFYQEKLNELSLSELNEVLLELEAQIKDLSEVLIAELALRDELEFEKELKNSFIQQLLLVQTKRRQHNLDRKRNKNGDKAAPNGVQQSKYLTTVIPYHAANGPPENATLQVLIKILKAIEQDSPAVPTLLTDYILKVLCPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJN1</accession>
    <name>A0A1D2MJN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Radial spoke head protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13439</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagellar radial spoke RSP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001041">
        <property type="protein sequence ID" value="ODM93237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJN1"/>
    <dbReference type="STRING" id="48709.A0A1D2MJN1"/>
    <dbReference type="OMA" id="RRVICER"/>
    <dbReference type="OrthoDB" id="313308at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009290">
        <property type="entry name" value="Radial_spoke_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21648">
        <property type="entry name" value="FLAGELLAR RADIAL SPOKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21648:SF0">
        <property type="entry name" value="RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06098">
        <property type="entry name" value="Radial_spoke_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="381"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="219"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="430" mass="50083" checksum="A3BD3CB2E02E9C4C" modified="2016-11-30" version="1">MPRNPIDQIVRLREYPSEQKDAIPHSPNLFVYCSTPRPVLDPEVSGGPYGRPLYRDNVPKPTGIHSYYNISWDPRVRRGDPLEVRKRKEQLECEKIRRKLTEPRKRTERSISRNQHRNERLSDPQAMIRAANMRYARLAISNLRPKEKDAFLVELTDELDQDEICYKGQRIGAAKELPKVPSRKRNLLDKASQVLPGEFFDFDREVVPVVERLVGAVCYQARMEVLEETELEALKLERELFREEKLREERELLKFKTRVERHITEEERQAALARQQTKDEAAGKISVSLFAGVHVKYGTDEGLRALGDDWELTEKIRQGVERQFTGWLNEEVDAKLTLYKNSTKLLDDIIRRVICEREAQCAASMWKEVYTEEPMRVFSGEMDSNIVPPPTPGTSEYTTDEEHEDKADPRENSVLTTPNFYFANEYDVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM98</accession>
    <name>A0A1D2MM98_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000877">
        <property type="protein sequence ID" value="ODM93981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM98"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="262" mass="29088" checksum="9230DB3917D869AF" modified="2016-11-30" version="1" fragment="single">MWLRSSFKGNHFILPIIFVVTFAQLSSGFFFPEMMNFFAKFQNQNNGGSGSGNVTSFRIPMLSPLSAPSRRVDVVTTIVSKAVEHPKVETNGTSSDNDTDTSSVLKLAVPTTTSITTSISASNHHDTIVAAPSTLTLPFTPNLFGMMSYVQALKDIKRNYKVNELERKIIFHNQESGDLMTRVLRTLIHKVVNKYQKQTELLKLKILKRQQKLQKFLQLPMVAQVIASDQQQLLAASANLGKDGTVQGTATHQQFSEEGNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMF6</accession>
    <name>A0A1D2MMF6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000837">
        <property type="protein sequence ID" value="ODM94240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMF6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="23230" checksum="4DEEE388039A6A35" modified="2016-11-30" version="1">MSSSSSSMLPNPCPCMTLQCGVKVVAAIDAACHAYATAATILVLAILDHIINEAGAGDNIVKSWTLVKVVYCLFIVGRIIGLVMAIVLYFGAQNNKACMGWTWIGSKALLMIPSSISLGSKKTHFKLDVSVSYLSLCWLGVGIYFIYVVFAFIQELRRQGQQQECDEMRDSATATVAPAPFPPQFQLQPSPLTSTDNNDNYGTVPSKPQPSFSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMM2</accession>
    <name>A0A1D2MMM2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000827">
        <property type="protein sequence ID" value="ODM94310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMM2"/>
    <dbReference type="OrthoDB" id="2016582at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904264" evidence="1">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="111" mass="12546" checksum="77872014687F1305" modified="2016-11-30" version="1">MLIWKLGVETVPLLYFNFVVLAFINQVGEEIREPHQLGGEETVQVETLGPLSDEAKDLTNSIGSQLIQQTRDTRAKHYLFQRISLAIQRGNVISIMGTLPPSISMEEIFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMW4</accession>
    <name>A0A1D2MMW4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carbonic anhydrase</fullName>
            <ecNumber evidence="2">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_12516</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000849">
        <property type="protein sequence ID" value="ODM94164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMW4"/>
    <dbReference type="STRING" id="48709.A0A1D2MMW4"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF265">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904300" description="carbonic anhydrase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="18278" checksum="B791D047E14826E8" modified="2016-11-30" version="1">MEFQFWFANLVFFVSSASAQFCYSDADGCGPDTSAWPSRCHTGTRQSPIDLPFAPPLSPPIKLSLDNYRGSSFRIQNLGQTISIDFGGVGPSSEPHSLPDPTTGQIRQIYFCFCPFSLGQTDLGGSEHCINGKCAAMELHLVHFLASYGSQASAVIVGIHSLAVIGVLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNP2</accession>
    <name>A0A1D2MNP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000797">
        <property type="protein sequence ID" value="ODM94512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNP2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="118" mass="13606" checksum="6392A067B30FE0B7" modified="2016-11-30" version="1">MNMEKFLLKDHPINLKFSVMNHNNGGNYRRGNAASAGAPEFFKPRHGQEYAKTKLPLLNFKRFQNLLPTATPSAGQKCEKIFIYFLCPMVDNHRIFEDDSYLNKIRIYGSPLDQLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP91</accession>
    <name>A0A1D2MP91_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Opsin, ultraviolet-sensitive</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_12001</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000769">
        <property type="protein sequence ID" value="ODM94681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP91"/>
    <dbReference type="STRING" id="48709.A0A1D2MP91"/>
    <dbReference type="OMA" id="WKMAKIV"/>
    <dbReference type="OrthoDB" id="9996086at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00577">
        <property type="entry name" value="OPSINRH3RH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="11 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="3 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="16">
        <location>
            <begin position="76"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM94681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="42757" checksum="B74C177B22FA8686" modified="2016-11-30" version="1">MSYVGSGGSSQALVGVGYYDVGGYFYLPGATQADGAPQELRDIIHPHWATFPPQNQMLNGLLAFLYFLFWIVNGFGNTAVIAVFIKSKSLQTPANVFVANLAVADFLMMLSQGPFYIWSVIRSKWWSFGVLGCEIYGFTGGLFGIVAILSMAAIGLDRFIVITRGMSGPRIKIVHSIFLVGFIWAYALGVCLPPLLKVWNRFTPEGLLTTCSFDYMNDNPWDKSFVIFIFTFAYVVPLVILIICYSQIVTTVWAHERALKDQAKKMNVESLRASNNDAKEASVEMKIAMAALSSVFLWVIIWTPYAVTVMIAAFGDRQLITPVVSMIPAILCKCASCVNPVVFAISHPKFKQAFRKEYAWLYCASRNAKDGNANNGETHSAATTVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPS6</accession>
    <name>A0A1D2MPS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000737">
        <property type="protein sequence ID" value="ODM94871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPS6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPS6"/>
    <dbReference type="OMA" id="VWQWDGR"/>
    <dbReference type="OrthoDB" id="8250257at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007541">
        <property type="entry name" value="Uncharacterised_BSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321:SF12">
        <property type="entry name" value="PLANT BASIC SECRETORY PROTEIN (BSP) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04450">
        <property type="entry name" value="BSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904341" evidence="1">
        <location>
            <begin position="20"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="23486" checksum="E1C1A71900EF1028" modified="2016-11-30" version="1">MRQLLPFLTLLVSAHLAQGVTIDVDTSAAPDLADFGRRVKATLEDWYPRVVDILNSPTFQPIDRIPIYFDPNYDGVAYAGGGRIVGAVNYYRSHQDDVGSMVHEMAHIIQGYRKCDGWVTEGLADWVRYWHYEPNRKPGKPGAGSHYTNGYGVSAYFLDWINSRWDPMNYWINKDCREGTYDVSIFPRLTGKTVDQHWDDMMNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR11</accession>
    <name>A0A1D2MR11_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000666">
        <property type="protein sequence ID" value="ODM95483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR11"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="229" mass="26621" checksum="AA26E9872FD0B2AD" modified="2016-11-30" version="1">MGKKLRKSRDPYPIYVQVPSPPKKQKWSITGDFLVDVVLLAGIIDMFIGFSLFYFAYLMLDGFDTMEDMLSTTTSLVATVAETTALKNQLEDMKRAELYGAATTCETPTMDTIDIVSGVYYVGLMIRLFVALVAFVSITFISSVLFLFIGIYQKRYMYCEIWIFFNRIFLATCVTLLIAGMYTNLFEMEVYCMVFFSYMFYRLSVEFGIRYFQRKTTEWNDLLGYCRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRZ5</accession>
    <name>A0A1D2MRZ5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Histone deacetylase</fullName>
            <ecNumber evidence="3 13">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_10820</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3 13"/>
    <dbReference type="EMBL" id="LJIJ01000613">
        <property type="protein sequence ID" value="ODM95857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRZ5"/>
    <dbReference type="STRING" id="48709.A0A1D2MRZ5"/>
    <dbReference type="OMA" id="HAHAPIT"/>
    <dbReference type="OrthoDB" id="5232919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11681">
        <property type="entry name" value="HDAC_classIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000002">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046949">
        <property type="entry name" value="HDAC4/5/7/9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45364:SF13">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45364">
        <property type="entry name" value="HISTONE DEACETYLASE 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037911">
        <property type="entry name" value="HDAC_II_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0678">Repressor</keyword>
    <keyword evidence="10 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 13" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="17">
        <location>
            <begin position="564"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="151"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="427"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="969"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="438"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="986"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1021"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="694"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="556"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="564"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="642"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR037911-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR037911-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM95857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1030" mass="110863" checksum="C5AF2F6AC419139F" modified="2016-11-30" version="1">MRVEMSTFLVSLSFPFLRTRSTSFHLEYWEQRKRQEEERERLEAIKKKEKHEQSAVASSEVKQRLQGFLLSKKQREQAAAKAGGVSIPNSVTSGGVPINSANPPTAGSGPFQSHPYRRPLHIAKYEEDFPLRKTASEPNLLKMRLKQRVLERRSSPLTRRRERSSYLKRRSYLAMDGGGGSAGSTPDSGPNSPPISCGIAGGTPHSGSGGGTPQHDEGGGGGGSPYGNSSYGPTNSASVCDLTLYSSPSLPNISLGRPIPPNSESKLAAVSENEVRCPVPPTSIMSSSGVPLLRMPFYGAPHIPMDPNELEALYRSGGIMALASYQAQATQAMNAAHAQGQENGDVARIGPGRTIHRPLGRTQSAPLPLGHPMLMMNSAVAAALSQAQPPNGTIPGSALMSQPQTAGQLLRQHIRQTVLTRVGSRGQMIGPMSRGLSVEEDSGEGEIDSDEASLPNQREFVNKMVQQHIHLKQQQQMPENLAVNSIIPNPVMTAGSVSAIPQRLHHSARPLSRALSSPLVAIGPSSPQDPSMQQGMSGKPGGTGLAFDSLMLKHQCLCGDNSQHPEHPGRLQSIWARLQETGLISMCEKIRTRKATLEEIQSCHSEAHTLLFGTNPLSRQRLELSRFPESSLPIKSLVRLPCNGIGVDSDTTWNELHTPSAARMSVGCVIELALKVATNELHNGFAIVRPPGHHAEPVQAMGFCFFNSVAIAARQLRSRLQMEKILIVDWDIHHGNGTQQIFYDDPHVLYLSIHRHDEGNFFPGTGGPTECGIEDGMGFTVNIPWSGGLNPPMSDAEYLAAFRTVVLPIAQDFQPDIVLVSCGFDAAAGHPAPLGGYLISPACFGWMTQQLMTLANGRIVLALEGGYDLPAICDSAQECVKALLGEPLTPIVEEELVRSPSSPAIETLLRTVAIQAPHWPCIKRYVSLITCSAIEAASTTIGDGGKLLMRDRVESETVTAMASLSMHHAAGGAGRCEGETSRDIPSSSPSANHSSSTSSRRRSSDMNEDSCTEGIHGTNEEPMDQDEPMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSP5</accession>
    <name>A0A1D2MSP5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000586">
        <property type="protein sequence ID" value="ODM96063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSP5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904480" evidence="2">
        <location>
            <begin position="26"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="114" mass="11618" checksum="A93B44F6805CD67D" modified="2016-11-30" version="1">MKSFLIATSVALFAIVAFEISVSDSLCWGTKPAISSNNSTCSNQTSLGLGLCQLRCLFCHAGNVSQRAGCITQNGTCLCLGKPGNGTVTTTLSPTNGTSTTSTTPSSNNTTSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTL7</accession>
    <name>A0A1D2MTL7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tissue factor pathway inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_10220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000538">
        <property type="protein sequence ID" value="ODM96459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTL7"/>
    <dbReference type="STRING" id="48709.A0A1D2MTL7"/>
    <dbReference type="OMA" id="PECEAYI"/>
    <dbReference type="OrthoDB" id="365605at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000020">
        <property type="entry name" value="Collagen, type VI, alpha 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF374">
        <property type="entry name" value="BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00214">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904535" evidence="5">
        <location>
            <begin position="22"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="6">
        <location>
            <begin position="79"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="6">
        <location>
            <begin position="151"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="6">
        <location>
            <begin position="244"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM96459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="603" mass="67346" checksum="68F669926C5BA52F" modified="2016-11-30" version="1">MGWKDFLSILLCIALIHSTIAYPRASASDEDDDTQQQQQQNIDSDSLEELTQKIHAKGRRPQKLQVTELEPEPEPYDPCLDARKIGPCKGRIPRFFLNQATGSCERFSWGGCSKTGNNFKELTECETSCSKHLTKAKLDVEQDQTSVVATCEKPPTVQGAPECEAYIPRWTFNSTEQQCIRFIWGGCAKTENNFATESSCKATCGEYSNLKSGATTPTPSGRDLDQQQNSNIEEPQVPLSREVCELPSESGRCLAFFERYYFNKINNRCELFTYGGCGGNENRFDTAEDCVRACGGDSPVSGECKAKQHFKEKTSRLNSAIIESSTNTYVQCADVECPWALYDHYYSLGCSPIYDGDSCCPTRYECPDTQQEIQNNTVPESRSLTLENETTTVGPDPTLPQQCRYRGKYYNVGDMVDAASDTGSCRAGCICVSSEPEAPRIVCAQIECAEHFRGRPPGKENCVPLYKKDSCCAHDYHCPEGGLTIVDPKDKDKVLPLAKCMVDGEGYYEGQRVYPNKSPCSKCLCQRNPNNVTSPEGQLYCEKIDCGIEIYYSHYLARGCAPVYYEKDDGTTSCCPISWECRKCEMKIKLATPFWKSCWNGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU02</accession>
    <name>A0A1D2MU02_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000556">
        <property type="protein sequence ID" value="ODM96284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MU02"/>
    <dbReference type="OMA" id="EHIDDEC"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19991">
        <property type="entry name" value="L 2 01289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19991:SF3">
        <property type="entry name" value="LETHAL (2) 01289, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1603"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="117"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1648" mass="189323" checksum="B4C0B4DB8BA91C42" modified="2016-11-30" version="1" fragment="single">PIMTGRTYPSSDAGGGSPTNAFSRVNSFFSYRMLVPFCVLYTQHCALEPVHAASKDKDVIEDVNGKEMQKLIEEKDYVAVIQDKRAAKLHGITNFPHLVYYRNKEPATFEGDLENEEQVLEFLTSLDAMDSPDRIEEVNAKILDKIVKEEDYVAVLFYAPDCRKCEKALRELENIDDEADELGIAFVKINDDELADEYNLDVLPSLVYYRNQIPIVFDGDLTKEEEVLEWIIGNKSTGDEDDDNEIESVSAKALWTLVESVDHLAVLFVDQSALSEVVLHRRRVRPPKHPVREDGRQEGQPRTGIDDIPAVVYYENNIPNVFDGDLRDEQEVLRWLLHQKESDEIEDVTSEMLDRLIRETKHLAVLFYDEDGDESEAVLAELENIDDECDAKGIAFVKIDDIKEAAEYGIEETPTLVYFENSIPSIFDGDLKKEDQVLKWLTEQMESDEIEEVTDEMLNMLINQNQQLGVVFYDRDQRKSQKIIEELENIDDECDKHGIIFVKISDQTKVNELGIGTPSLIYFENRIPHLYEGDLSDEEATLNWLLHQLRSDEIEEVTDEMLDILIERHQFVAALFYDKDDKDSLKALQELENIDDECDAHGIVFVKIDDDAEAKEYGFDELPVLVYFEDKVPSLYEGDLDNEEEVLKWLVHQKTHDTIEEVTDEMLQKLVGTHQYVAVYFSGPCVEEEGADDPSNCDEILDELESIDDDVDEAGIIMVTTEETTFAIKTLGIKIFPALVLFRNEDPLIFDGELTDEDEVLSWLTDDDSLELPDRIEEVNLKMLQRLLDTTENVVVYFYRDTDKKSVRILQELENIDDEADAANIAFVKISDDSMLREYDLDPLPTLVYFREKFPMIFPGDLSREETVLDWVMKLKEAPRDTIEEVDHRTLRMLLDELDHVAVLFHEENCPECDDILKELEKIDDEADDVGIHFVRTEDTSVAEEELRIKDFPTLVYYQGGAPSIYRGSLDDEDEVLGWMRRIYIISEGLRLEVSRRRSATEDKTDCSDCENYCRKKYGESTEDEDEEEEDDDDEEEVSDEDEDSEEYIAPEEKARRERKLDIDNLKTLPKKKKSNSVIGKVVSKILKLFAFYRHRDLVEEGEVLHWLVYQRKFEALPELTRADLDDLIGDSDYLAVVFFSNYTDEDSARTLRRASLIAEDAAAFGIPIAKMPDVLMAKKYGIRDHLVLYYSVEYDDDLEDEEEMLDWLTSPENMILKDQIEVVNRKMLDRMRENTAHLAVLFFSETDCKQCERVVSALEEIDDDADQNGIAFVRIDDWELAKGWGVHALPALVYFSIGAEEPVIFAGDLRSPQKIMEWLLNRKDPGGVTIEEVTSDEVAKLPCRACDTILMELEKIDDECDTYGIHMVKIADPQLAKRYGIHTFPALVYFRNGNPLLYEGELKNEDADDEEECGEECENILLGLEEIDDEADGYGIDMVKVVDGDDASEFNIMTTPAMVYFRRGTALIYEGDLMDTAAILGWLTSNEAFELKDEIEEVNRRMLEKLLDDNDFVTVFFFDSEDCSKCGEILEDLERVDAEADNLDIIFVRIDDVKYAKKWGVTKIPALVYFRRKFPSIYRGDMTDETAVLDWLQKNRYKQPELSLFVFAIATMGLCFVLYTIFILVFLKHPSGGGESEGGAGTSQRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MU28</accession>
    <name>A0A1D2MU28_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000522">
        <property type="protein sequence ID" value="ODM96590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MU28"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904555" evidence="2">
        <location>
            <begin position="27"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="339" mass="38107" checksum="082861C8879B152A" modified="2016-11-30" version="1">MIRYLKTTYNLLIFTLFSIMLPAIFAAKISPCRVQNIIAQPQFGISLSTKKMVDIIQIPPLLSQTLQIGICLDNNRNFTDYTQPNLSTYICRQRYSAVEVYSKSEDASPKTYQSPIAPEQGRERLLQKLVKTFVIVEAGCDFSFNFLPVIGHQLKMDSNKEQFYSPEAVGISSLYDEKATKDLKPETPPSVTNVVEAAEAQMGSKSSILSPRSMDRERKNFFRNWHFKSARKSLEPNNTSKVNLSQHNGTAELSEPAATNVTNDDGGTALQSTSNDDLNENREEEGEEKVEQEEDKKVGNSEGEFYLNPKELGLPILILDSSIDPVMKLISRFINESND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUK4</accession>
    <name>A0A1D2MUK4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Mediator complex subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED8</name>
        <name evidence="10" type="ORF">Ocin01_10189</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000535">
        <property type="protein sequence ID" value="ODM96494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUK4"/>
    <dbReference type="STRING" id="48709.A0A1D2MUK4"/>
    <dbReference type="OMA" id="NRIHCWN"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019364">
        <property type="entry name" value="Mediatior_Med8_fun/met"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074:SF9">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10232">
        <property type="entry name" value="Med8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0010">Activator</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="227"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM96494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="258" mass="28323" checksum="E80CCBCD70CF0A97" modified="2016-11-30" version="1">MEFALDLMLQRVNEMKTTLSSLIMKLEHDHQNVNFPVFLDSFSVISGQMNTLMRLLRSDKVPLLKALTVLPLSLNPEADQALLAMTEGRLNCFNHEVVPDYLRTKPVPEVESKHVTVEMRASQANQDIINKQSAQLTKMANHVNDLITSARDEWEASERGGIPATFSNNDTQELVAALYSGKAFKSLPGPPPVRQPATSTSAPSAQVAAKAPGPIKTNIKMVAHKTPLKSDEKMIPSQPSTTNKDFNELHVAAADIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUQ5</accession>
    <name>A0A1D2MUQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000528">
        <property type="protein sequence ID" value="ODM96544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUQ5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="29" mass="3096" checksum="EDC55140AAD05545" modified="2016-11-30" version="1" fragment="single">MSVIQFVKLSVKAKTPSKGSKYAAGIDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUS5</accession>
    <name>A0A1D2MUS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Folate transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09838</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000498">
        <property type="protein sequence ID" value="ODM96849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUS5"/>
    <dbReference type="OrthoDB" id="18814at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090482">
        <property type="term" value="F:vitamin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002666">
        <property type="entry name" value="Folate_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10686">
        <property type="entry name" value="FOLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10686:SF18">
        <property type="entry name" value="IP11787P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01770">
        <property type="entry name" value="Folate_carrier"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="47577" checksum="EAF0137E782C9126" modified="2016-11-30" version="1">MSSDISNDRHESAHVNRLARTGSKHKRKPSSLSKAVKVTKKFYLQQNGSRLETNCICHVWDGLFKEFLPSAPFFIEYAMDKSHGNFSQDEITREILPITIYGHFISLLIFLLITDLLRYRPIIILGGLSAMACWTITIYSYHTKRMQLFVKFSNSIEHSSEVAYITFMYEIVNRTFYREVTSPNSWCNACWQIIGGALGQILLSYKLLSLDNMNYTFALGSTFSFIVFAMFMPGNQMFVIHEAEDPSQDLEKATSKTGKLNSKPDEAKPIQMNVRRWSMWWSMSRAIYWQIELYTESLWKEIENESHQHPLNGAVDATHALISSIDCCVVAIHKSSMGKVGWKAIWQSEIASSLPDHKASFIFGINALMGIMIQAVMTNVVTNKLTALLWILEASSLFMDYSIVKSVVYNICVEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVA6</accession>
    <name>A0A1D2MVA6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heterogeneous nuclear ribonucleoprotein L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09754</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000487">
        <property type="protein sequence ID" value="ODM96926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVA6"/>
    <dbReference type="STRING" id="48709.A0A1D2MVA6"/>
    <dbReference type="OrthoDB" id="302770at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12424">
        <property type="entry name" value="RRM3_hnRNPL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15592">
        <property type="entry name" value="MATRIN 3/NUCLEAR PROTEIN 220-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13893">
        <property type="entry name" value="RRM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="105"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="230" mass="25689" checksum="28A6C2FE4F677B79" modified="2016-11-30" version="1">MRTTVPFANGPYDRYENGYSRGMNGPTAPGGGPPSYHDQPAYDRYSCDSQELWKPCQERSYMGGVPKEDYPYRNGPMRSTPPNNGELVPSSGSVSGPARPMQQGAVMMVYGLCKDRINAERLFNLFCLYGNVVRVKFLKSKEGCAMVQMGDAISVERAMSNFNNTFMFGSKVQLGYSKQAFLSDVQQPHTLPDGSPSFKDFMGNKNNRFLNPEMASKNRIQPPTKVKLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVB6</accession>
    <name>A0A1D2MVB6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000498">
        <property type="protein sequence ID" value="ODM96848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVB6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="50" mass="5415" checksum="7EC5F63A7AF1871E" modified="2016-11-30" version="1">MSETGSKANGERRIRQFATVLHPSSSYILGPTVNGWEGRGYTAPLHGTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVK3</accession>
    <name>A0A1D2MVK3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SNW domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000474">
        <property type="protein sequence ID" value="ODM97089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVK3"/>
    <dbReference type="STRING" id="48709.A0A1D2MVK3"/>
    <dbReference type="OMA" id="FYDHTND"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="3">
        <location>
            <begin position="147"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM97089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="58172" checksum="C7D9DCFE751A08D7" modified="2016-11-30" version="1">MSSLASLLPNPSHVVRDRDDERALMRPPSTALVSLRESRAPPYGKRKGWIPRSAEDFGDGGAFPEVHVAQYPLARQGHSKDKIVYSKYTDLLPKEITSEDDPELQKPDEDNIKEITEKTREALEKLTQSKIVAAMPVRCADKKGETQFIRYTPSQQGQAFNSGAQQRVIRMVEVQRDPMSPPRFKINTKIPRGPPSPPAPVLHSPTRKVTAKEQKEWKIPPCISNWKNAKGYTIHLDKRLAADGRGLQQVHINENFAKLAEALYIADRKAREAVEMRAQLEKKLAQKEKEKKEEHLRALAQKAREERAGIRHSAATEKEDDVKERDQLRHERHKDRQRERNIARAAPDKRNRLERERERDISEQIALGMPAKTISGGETQFDTRLFNQSRGMDSGFADDEAYTVYDKPWRQGGDVAQGIYRPKKGSDNDIYGDDLDNIIKTNKFVPDKEFSGTDRAAGGSSRSGPVQFEKDEEDPFGLDQFLTQAKKASKRGADETSKDKGSSSSSDKRRRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW18</accession>
    <name>A0A1D2MW18_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000479">
        <property type="protein sequence ID" value="ODM96994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW18"/>
    <dbReference type="OrthoDB" id="10023262at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="1">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="110" mass="12317" checksum="F0E514D901A2104A" modified="2016-11-30" version="1">MTPLNETALAAYIWIHGTEVSTEDTDIILSKIDPKTFWNVVKTHCSSDSEACNIACRLQKLPASGSSIERCFSTLSSIMTKTRNRLGIEKAGKLCTIYQSLHFLPDEEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW22</accession>
    <name>A0A1D2MW22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Facilitated trehalose transporter Tret1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000468">
        <property type="protein sequence ID" value="ODM97152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW22"/>
    <dbReference type="STRING" id="48709.A0A1D2MW22"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="27"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="524"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="565" mass="63048" checksum="5161DF56780A38FC" modified="2016-11-30" version="1">MCPDPLIIPKLDENLPPIVPTLWKCRRQVYGSIVCTLGVFSTGCVFGWASPGIEDMINDGVEFDEATMASLFIVGSLVSGPISGYSMLKIGRKYAMLLFGIIFSLGWVLMGCAKLVLSSSNMGAVTMMYIGRFVTGFAGAACLAISPIYIKEMCCEELRSKMGGMVPLQLIVGFLYTFVMGSFLSWYALSFVCLIFPILLTILMIWMPESPRQEINTLSDFNSNLIGEYIYINASRLHCLVRYLIKKGRYQEGEQSIHWYYRGFKFEEGERVFRHLKMAIDYIKDPTKVKHAAKRQAEDNVEFKSRAVLRPLVVSALLIFFQQASGISFISTYTTDIFKASGDLVSPKVGTILVGLSLTIFIIITVFFLDDYGRKPILQIGTLIEGLCLFALGTFFILKEKGSSAVEYMRWVPVVSAVTFVAAYALGMEISNTITNTTYWLTAFIVTASLPALRNSVGYHFCCFFYGTFCFISYFFVTFCIYETKGKSTEEIMNHYRGSVYKEEDETGNDKHSYSLGARHAKSFGSLGPAKKQSHHAAGEGRNSILSTDTGSSDVNVLFETRESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWI0</accession>
    <name>A0A1D2MWI0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Double-strand break repair protein MRE11A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_09265</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000445">
        <property type="protein sequence ID" value="ODM97417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWI0"/>
    <dbReference type="STRING" id="48709.A0A1D2MWI0"/>
    <dbReference type="OMA" id="ESCMFNA"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097552">
        <property type="term" value="P:mitochondrial double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000011">
        <property type="entry name" value="Double-strand break repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000882">
        <property type="entry name" value="DSB_repair_MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 17" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 17" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 17" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 17" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="19">
        <location>
            <begin position="295"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="510"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="546"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="588"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000882-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODM97417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="665" mass="74547" checksum="5137E6E15665CA21" modified="2016-11-30" version="1" fragment="single">VPSTGDVVDEHTFKILVATDNHLGYCDNNPARENDSFDTFEEILKLAVDNDVDFVLLGGDLFHENKPRPNVLRKTTELLRKYCLGSKPVSFQYVGNPERDFPNEDDPEVNYYNANINIALPVFTIHGNHDDPVGSTKTSAVDHLAAAKLVNHFGQWENLNNITVSPVLLTKGHTKLALYGLGHLKDDRLNRLMHDKKLTFHGPEEDPKAWFNLFVLHQNRVKHGPKNYIPENYIPGYMDLVVWGHEHECRIHQELAEGLVKTYICQPGSSVATSLCAGEAVEKHVALLKINKRMFRIEKLKLQTVRPLVIKDITAKEILEKCPRNASSKERSKHMEKYVENVVNGLIQDAEDLLTGHEKQPTAPLVRVRVFHDDVEDTFNPIRFSQRFVDKVINDDIVMFKKTAVKREDGIEIDADEIGEMMTHYDEDDLEGHVENIVENYFTQARNNDETNSLLEVLSERGLSEAVKSAVEKEDYQAISIVIESQIEKAIKHLINKNVTEETVNDELIEFRQRRSNMPDQEKKEVDEMLSQRKPKKTKASNGGSDGEEGVENANNEDGDSPIEIDDDADDVPSRSRGGRGAATRARGAARGRGGRGRGKNAAAVSPDTSPPPTSSRGRASARGSRGKGAKETSSRGKTLVQTTLTNRRSPRKASQAMHFDDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY22</accession>
    <name>A0A1D2MY22_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000418">
        <property type="protein sequence ID" value="ODM97704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY22"/>
    <dbReference type="OMA" id="HYMNYFN"/>
    <dbReference type="OrthoDB" id="10580357at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="58543" checksum="2FC27EB96DB1AD00" modified="2016-11-30" version="1">MVADDDKKGAEDDKKGAEHEHTAHSRQTQHSKELINAFKPIKYFLTVIGQMPFVIKAKKDGTYSFKFYKLSGQVLVYFFMFFISSFLYLVVTIGIITFILDSVFTYIKPERTVIVKDKDDGTTDTLLWERYLIRHEMVSMIVVWSWLTVAFAGSLYIVVSSKYYVHYMNYFNRVVQIMDMDMTPGVSAYLFFNNILSLGVAVALTVGFIVGLIFEGFSAVTNTASVISNFIFRVFDIEILDYGSNAMIWSQVMGYLIMIYALFASRANVIQFLFFSQLLKNGSKIWNERLRKVLTHESIDSKDEHDQFNQRLEPRLIYKDHLLIVQLYQMTENVFGIILFAYYSLTIISVVMELYQLAALQGFGSARSTTLLGNENDAKVQKAQLYEVRLGISSGVDKSQENEILGTAGVALLLLLQNVYFCYRTTVDAAKAYEYAMKGFDILRRHGLMYCKNKTDRNFVLSLYFSFAKNNPLQLTAGGYFAVNKVLLVTMSATVVNWAISIYQTRIDQWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYC2</accession>
    <name>A0A1D2MYC2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-BAR and double SH3 domains protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000394">
        <property type="protein sequence ID" value="ODM97941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYC2"/>
    <dbReference type="STRING" id="48709.A0A1D2MYC2"/>
    <dbReference type="OrthoDB" id="6250593at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="25697" checksum="56C946AE427EB693" modified="2016-11-30" version="1" fragment="single">QHICRNYNACFFYILVSDFTQQLSQLHEQHAVQLQMLIENYRKRNAELRKERPPCNSSMFQIWETLLQEVEIDSQAHSDISASLARQVARPLLEKTFCLKIQSRKVFAHRESFETVLSKTEALLSKAYRDYSDACMQHIQMCSNQSLAQYYEAHNAYIQQLRGTNSMLKEYHSETLPALLQVRFFFCDGAICYWSLVCCFLAEGYVISSMYLKSNLKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYU4</accession>
    <name>A0A1D2MYU4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000375">
        <property type="protein sequence ID" value="ODM98170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYU4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="10913" checksum="B78CA62952310AD3" modified="2016-11-30" version="1">MESLNTEGITFKKPSQNNKISRSGTSGKRKLDDPNSSKFVSDDINLDILRTFEEPSKTIPRRIELYNKNLELLKKNFKVKSWWYHFYARKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ60</accession>
    <name>A0A1D2MZ60_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Beta-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08340</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000362">
        <property type="protein sequence ID" value="ODM98337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ60"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ60"/>
    <dbReference type="OMA" id="KDYMPYV"/>
    <dbReference type="OrthoDB" id="1657402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026283">
        <property type="entry name" value="B-gal_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048913">
        <property type="entry name" value="BetaGal_gal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21467">
        <property type="entry name" value="BetaGal_gal-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006336">
        <property type="entry name" value="B-gal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase 35 catalytic" evidence="8">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 35 catalytic" evidence="8">
        <location>
            <begin position="113"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase galactose-binding" evidence="9">
        <location>
            <begin position="563"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006336-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="653" mass="73165" checksum="2BBC06C978B465AD" modified="2016-11-30" version="1">MKGAAGRVTAEDNEKNMHTNAGGDNQEKGLACSSLTTSQDLPSVYEYFANGTELTGLVAGNRIFTLNGKEIRIISGAIHYFRVHPAQWRDRLRKLRAMEQIQWKPMLHGTFMKDLLVLIRPGPYVCTEWDYGGLPGWLQRDPDMKVRENNKPYLDRVKIYLDNLLPQVTDLQFTRGGPIIAIQIENEYGAFSPRHPEYLQYIRDLYNEHGFDESLHFTSDNSFGGSGIEGSLPGVLQTANFQNSPTGLFNRLREVQPDMPTMAMEFWAGWYSHWGAAKQGGTTPEFMASVLEEILGTWNASVNFYMFFGGTNYAFMAGGNTRGDPPYIVQMLQATVQKYYDAPLSEAGDYTRKYDLAADLIARYAIPQLRKPQRPAESAKAAYPTLGLQRYLTYSDIIDKIPSSSKFQLEKPVSMENLPMNGDSGQGFGYIIYRKNVFIAPNDDSSFRGSWPRDIGFLLVDGELVQDGSDLWINSIKEFPLSVTQAGNHTVDLMVEPMARVNYGTAADFIQQKGIAPIHQSKIEINGEEVTDIEVIAAEFSNAWVKQLSGFSEVGNATLRAPVLLQSSFNIEGEPADTWLDMSRWNKGVVFVNGFNIGRYWKGTSTEFVCCCSSTQDGRKYCKFVITIFEQVQPHTEIIFSDTPNLGEPPSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1A4</accession>
    <name>A0A1D2N1A4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000301">
        <property type="protein sequence ID" value="ODM99073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1A4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="24682" checksum="4CD15D5EEEA1E021" modified="2016-11-30" version="1">MAEKARRLAFNPCAVNFSKMSLAKQLWNLVKKDKAMNMELESAKANLITSQLIWQKSAIDVANIQFAIIIEDIQMEYRLRQVGNQQLTDESSEDGELVSPTKPISHYKTMVDTDKWTNFRSRLNQANAKFNQVKLTWLSAKEEVTIWMTMKEIITKVQRWKESEAIANYWASKYDDFLEEWENIKLELEKCIQYCANLAAISEEKPDTELSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1C7</accession>
    <name>A0A1D2N1C7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000300">
        <property type="protein sequence ID" value="ODM99093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1C7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904871" evidence="1">
        <location>
            <begin position="24"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="76" mass="8173" checksum="E59C5F75D5F462BC" modified="2016-11-30" version="1">MASSRFVFIVLLVSAVFLPLCASSLEKGSIYNLRNVADESYLRVESGGALCKYMGPVVTHPLSILLQLLSVGVTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1T6</accession>
    <name>A0A1D2N1T6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase-5C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_07669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000304">
        <property type="protein sequence ID" value="ODM99014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1T6"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="35"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM99014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="80" mass="9222" checksum="B3777826B896A3F3" modified="2016-11-30" version="1">MLRGLVQYILVAVVALIAYFYLNEFFVYFGEPVYLDTKYGTLKGKIQPIRGGRQVYSFTSIPYGKPPIGDLRFEVVKVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N208</accession>
    <name>A0A1D2N208_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_07379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000288">
        <property type="protein sequence ID" value="ODM99302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N208"/>
    <dbReference type="STRING" id="48709.A0A1D2N208"/>
    <dbReference type="OMA" id="CHMLTFV"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008686">
        <property type="entry name" value="PRK11705.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF1">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM99302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="410" mass="47861" checksum="31E2A96D371833A1" modified="2016-11-30" version="1">MSSKVTTMMTNAVHMLLVSIVGAIKWFEIATYKWTNTYLRGMVDAAFRKGKLYVDGPKPYDPQVKNKEEFYNRIIENPSLGIGECYMEGHWECEDVEEFTYQIFMNKIIKSYMNPINKFLNFLLFKVVNLQTKQRAWEVGEKHYDLGNDLFESFLDPSMNYSCGYWKTAKNLHQAQLDKMDLIGRKLKLKPGMKVLDIGCGWGGLCKYLAENYGVSVVGCTISVEQAKIARERCANLPIDIRLVDYRDLDEKFDRIVSVGMFEHVGTSNYRTFFEVANKCMNDEGLFLLHTIGVSHNWVPLIESWFHKYIFPNGILPYHTEILQSVDGLFVLEDWHNFSTYYSNTLRAWKDNFVKNWPKLKAAKKLDEKFFRMWTYYLSISSAAFRSRKYQVWQVVLSKDGMLGGYESVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N232</accession>
    <name>A0A1D2N232_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_07364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ubiquitin-like protein involved in autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATG12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000287">
        <property type="protein sequence ID" value="ODM99343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N232"/>
    <dbReference type="STRING" id="48709.A0A1D2N232"/>
    <dbReference type="OrthoDB" id="10003551at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="1 4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="209" mass="23465" checksum="E4B1B5C6EAF44A67" modified="2016-11-30" version="1" fragment="single">MENEAADSTADSLTSEVTNSAEKSSGDTEGNNVTITSEPISQLSRERTDSGTGSESGRGAGAGGKDRDKINILLKPVGDAPILKNKLWSVPSERQVSQITEFVKKYLKLEKNQNLFFFVNQLFAPAPDQCLRDLYECFGSDGKLVLHYSTTSVDWKSKDPEEDDLQISRALRNHFWFSRKYSFTQHMSYDSGSVTFSSHLRRESNHNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N246</accession>
    <name>A0A1D2N246_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_07348</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000287">
        <property type="protein sequence ID" value="ODM99342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N246"/>
    <dbReference type="STRING" id="48709.A0A1D2N246"/>
    <dbReference type="OMA" id="CMERCCV"/>
    <dbReference type="OrthoDB" id="5989317at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF2">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="8">
        <location>
            <begin position="72"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM99342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="360" mass="40167" checksum="CB6072F7FB06C3C2" modified="2016-11-30" version="1">MADPNNQQSNPNPYQDTTFLNHPGYRPYQDPNNPDIDLNKYPEPKDSTNKIRGKSELLETLVGGLEPELVVAKGFYFFFYAAFGSLFPLMGVYFKQLGLNGAQAGILSGAGRWSSTWPRRSGHNRLKTVLLASLGCWILFTFPLGSIQPEPVGCIKKWNMSHAILNPPEPVQVTFTKREALPEEYYDDSDSEYVQPPLALPLEESESENLSRSKRYIPRPIPGISPLKVSYAINYNKKENSNWVSPSYSSQVFKKDDVSKVFFLLLLLVILGEAVSSPSIVLADTAVLGFLGDQAATRYGHQRMFGSVGWAISMFFIGIALDHSTFPARKCQALPQEKNYTVCFSIFVVLMGWPRCSLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2M6</accession>
    <name>A0A1D2N2M6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">EF-hand domain-containing family member B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_07375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000288">
        <property type="protein sequence ID" value="ODM99304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2M6"/>
    <dbReference type="STRING" id="48709.A0A1D2N2M6"/>
    <dbReference type="OMA" id="DCIRPIY"/>
    <dbReference type="OrthoDB" id="2096280at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057428">
        <property type="entry name" value="EFHB_EF-hand_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040193">
        <property type="entry name" value="EFHC1/EFHC2/EFHB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086">
        <property type="entry name" value="EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12086:SF12">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING FAMILY MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25325">
        <property type="entry name" value="EF-hand_EFHB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EFHB C-terminal EF-hand" evidence="8">
        <location>
            <begin position="590"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM99304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="706" mass="80120" checksum="AE647B3880D4497F" modified="2016-11-30" version="1">MVATGENCRCPDPKVLPLLPVAYPNENRSHIQVQPVEGTPGIDPCCKPSPTPCFDESFSRCKPIACTAGAHDPTAAGSCYDSTSIHQRQCECPKCTVELHKFQEDGRVCYQHTDGNQFHDIRRIHPDPEIQAIRDRMNSSESVKNTLRWCNTDESLSCVDRRFRQAQTGITGQAAIHYGAAQDVDYPRELIHGVLSDEVTPATHLVNPPPKKWVDQLLNDVKESIYESNRVRPIGKSHDQKERLPPTIHPDETAFGKPSDKSISASILVNPPKDRFQVENEAKEFQPMYKFTHGDYDAGEQLCRNYVANNFSKHNTFGMKTPHDVAGRWARKIISTWRTCDPDPAYVSKIYADHLDFRYPKLGKQRDATCVGRDRGDEFVYGAKTTKDEEQRPVQELIFNRCPNPGGDKAQKMMSNLKTWIDKVRKACRDSLGPDLEKFYEEIIAADPNCNGTIEWDPFIKAMHMQHIPRTLGEKDFMECLAYVGVFHPSPCDKLEYYKLMDLIKGYEDPMFGCKTTTLKPYYIPHTNGCVHFRTTYSDLTSNMCVPPNCLTTMKEQRVNGMPSVRYDRLPRKIKSTKDTTNYGDDGDAYSLIFPSVYTSQGITIRDAFKEMTKEQMCRLLCLANVPLTHEQINRTWEAAKCLDPEGCGRVSYQTFREALCQVCDEMATEQGCPAIYSLQPSDCPPFYPRYPKRHGKPNPCAGVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3F1</accession>
    <name>A0A1D2N3F1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="4 10">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_07114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4 10"/>
    <dbReference type="EMBL" id="LJIJ01000270">
        <property type="protein sequence ID" value="ODM99584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3F1"/>
    <dbReference type="STRING" id="48709.A0A1D2N3F1"/>
    <dbReference type="OMA" id="SWIKINA"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016325">
        <property type="entry name" value="Phstyr_phstse_ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM99584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="350" mass="38698" checksum="DE190D5BE6C96B24" modified="2016-11-30" version="1">MAALGDGHIFAQPKREIISPMDLDKWLKSEAYQELIGFLESLNEAVKGKPLSVSVTPSPVVAAIVEVLNRIDEIIDQTPAIDQPQRFGNKAFATFYSQLQNSISSLLKSALPDNFHGSVDEISVYLTESVGNSTRIDYGTGHEFSFVMFLYCLFRIGALDTQKADDRIAAVTCIFSKYMVLVRKLQITYRMEPAGSHGVWSLDDFQFIPFIWGSSQFVGNPIIDPSSFTDSETVHKLASEYLFMGCIEYILKVKSGPFHEHSNQLWNISGTQSWSKINQGLIKMYKAEVLAKFPVVQHVLFGSLLSIKPMDPTKMGKAGRPGTGIGILTSGLKGISLPPQLNPADEPNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3X8</accession>
    <name>A0A1D2N3X8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Homeobox protein araucan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000241">
        <property type="protein sequence ID" value="ODM99986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3X8"/>
    <dbReference type="STRING" id="48709.A0A1D2N3X8"/>
    <dbReference type="OMA" id="GRTIMTD"/>
    <dbReference type="OrthoDB" id="5399138at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="10309" checksum="1EB06DBCB33D7392" modified="2016-11-30" version="1">MLILLGSPNSSSGVMSGSTSPTGVTTSPGTSCCEGGRPLVTDPVTGQSVCSCQYDPARLTLSSYPRLTGYPPNPYAPATEQNPYPSLESSAFYSPLAVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3Y7</accession>
    <name>A0A1D2N3Y7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein turtle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000265">
        <property type="protein sequence ID" value="ODM99645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3Y7"/>
    <dbReference type="STRING" id="48709.A0A1D2N3Y7"/>
    <dbReference type="OrthoDB" id="6234674at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="42892" checksum="26B7738A1B2E1854" modified="2016-11-30" version="1">MLYNVVDESSSDDGGFLAPRPLRYFPRGRRRFNLVLPGSFVPSSSLIRPETLVVPRPFASSPIPARSRSVISGIQRQFSPSSADLSSVPRFPVLVQVHQPPYLWKTATTGRHFHPRIPSDPTPPPWEAERIRDNLARDLEYLERQVPPFLRHPPSNSQQQLGSGSVPFDKSNLGSSISTRIQQERSSSSGFQSGSKSTTSAFPSGAGSSGVGTGLGSGGTTSSEVLLRPVTLSGREVERLRMMEGLFPGDSFPPAPTIPSRSFIPPRTYENWPRREPTPPIYAMARSPSFDIEDTQITVPLSEASPGTRTLLDMSVDDPYEFDAVIPDTSPEIAYPSQPPPGSTATSMSRFKRTRDKYENMEARVAAMKEEFFEYRRRQKKRMESAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4U4</accession>
    <name>A0A1D2N4U4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell cycle checkpoint control protein RAD9A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000218">
        <property type="protein sequence ID" value="ODN00284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4U4"/>
    <dbReference type="STRING" id="48709.A0A1D2N4U4"/>
    <dbReference type="OrthoDB" id="60092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="458" mass="50698" checksum="DA6E69DECAB6D88C" modified="2016-11-30" version="1">MKVTIGNANLGTWCRIVHGLTQVGDDEIHFDASDGILTLSTYNASMSNYATVLFFRNFFTSCQMNTDSDEPEKIAVPAKTILKPYRTLKVAKSYLSSEIKYIPSEDFITVTSEGKTHVSTTYKLGATESSSEIQFECDPYAMKNILKTDAKVLASGLSNFNHMKGLSELTLKIQGERVMLKNTVTDVARKDGTVVTEYNLTSHDFIEFEVEEETVELAFGFREFKIFTAFAEQLKVPVSIHFQSQDDPVIVTVKTQSFEARLCMATRIRDPFEMTGADGSQSTGGSNGRISNVTSQSCSESRNVSLEVNRRVDSGTLEAERVAVEASVPEEPAAKRPRRTDLHVEPSVDLVELPVGQFEASVNQVEVSVGQVEPSMDHVELSVDQEDADGNGMVIDTDPVALNIHSMVQQMEKRAKSIGYRTLQNLVNTPRITEEEYLESLPGHDQILCPESDDDESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4V6</accession>
    <name>A0A1D2N4V6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Inosine-uridine-preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06372</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000215">
        <property type="protein sequence ID" value="ODN00309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4V6"/>
    <dbReference type="STRING" id="48709.A0A1D2N4V6"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02651">
        <property type="entry name" value="nuc_hydro_IU_UC_XIUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="9"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="389" mass="43447" checksum="E07A283750FD8E07" modified="2016-11-30" version="1">MSAQESIPVWLDCDPGHDDALAILLASHSQRIQLLGISIVHGNDTVEHCAKNALRILWACGVKGIPVYKGIQRPLVREPKFCPEIHGIPGEQGVAGMCGYHFPDDIIFSDPNYKVEDTHGVLAMATAIKANPKKVTVVLTGAQTNFAFAIRMYPELKDNIEKVIFMGGAIGLGNTGIAAEFNIQIDPEAASIVFHSGLPLVMIPLEVTHKVLVRNNILEKLANIDYEQATAPECTNEKKDLEKLPHRHLEYREASDAVERRKRMQLDSQKAVISKLTRFSSKFAECFYQLLTFFQTTYCKEFGFESPPLHDPCTIFYLTHPDSFQTLSLYVDVETGSEKCLGRTLCDINSLSKQQPNVLVCTDIDVDIFWKNMLHCLQLASKLSPMNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5G5</accession>
    <name>A0A1D2N5G5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Ribonuclease</fullName>
            <ecNumber evidence="15">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_06187</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14 15">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase HII family. Eukaryotic subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the mitochondrion-specific ribosomal protein mL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="15"/>
    <dbReference type="EMBL" id="LJIJ01000204">
        <property type="protein sequence ID" value="ODN00494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5G5"/>
    <dbReference type="STRING" id="48709.A0A1D2N5G5"/>
    <dbReference type="OrthoDB" id="5870821at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07181">
        <property type="entry name" value="RNase_HII_eukaryota_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000006">
        <property type="entry name" value="39S ribosomal protein L39, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.460:FF:000001">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000016">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.460">
        <property type="entry name" value="Ribonuclease hii. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004649">
        <property type="entry name" value="RNase_H2_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023160">
        <property type="entry name" value="RNase_HII_hlx-loop-hlx_cap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00729">
        <property type="entry name" value="ribonuclease HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF7">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51975">
        <property type="entry name" value="RNASE_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14 15" id="KW-0540">Nuclease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9 18" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="RNase H type-2" evidence="17">
        <location>
            <begin position="111"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="855"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00061231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN00494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="883" mass="99984" checksum="7EF62EE40954476B" modified="2016-11-30" version="1" fragment="single">ENSSSEALITKLTMSSSDTEMEVKSEPIPETTISVKDEELDLDPPEDSIIKKETKVETSKGSGEIDLTGNDDVDDLTCGVGVYKDALKKFAANPDDDVTVYHVTEKCKKVSCYVGIDEAGRGPVLGPMVYSIFACVADEESINEKKKKGQSLSKIEDCPPVLLDKLAKLNDSKQLTEKVREEIFQKFSDMDHIAFGLKIISPSQIANKSYRRQKYSLNEISHNAAIELIQGFADRGIKIERVYVDTVGPMDKYQKKLEVTFPDLRFKVDKKADAKYKPVSAASVCAKVTRDVALKKWKFPESENLGSSSGWGSGYPGDPVTKRFLRKNIDPVFGFPNIVRNSWSTASELLEKCAVKIKWESDEQDEVVAPKISKYFGKKSAGDENVDENVSEMSRRKSQFFSYRDLYQTTFVLDEVSKFLLLYSFFMTSNKLIISFLRNLEYSENVEVVVHKSVSPKHRAAAESRLKSKSTIVWFLGRFMSLPLTNLKDSIMGRLSGLIGKCRYSGLIHIQKRYFQMHSIQGPTPEEIEGVRKDLFGKLSRENIRSILQHPIPSVNNPVVRAKRSKMFSEEKDNQYKELGRIEKIDVEYVGVPENVTLMMNKGISTPYDCAKHMSEMHLQRSVVAEVNGQLWDMHRPMGESCKLRLLHMKMKEEDPFNINKIFWRSCSFMLGAVAESTFHDHIYVELHSFPSANVRSGSFVYDVDLKIKDWKPNSDEMRVFSLEMRKLAQKNLPFERLEVNVDLALEMFEDNQYKKKQIPEIAANSATGKTVCLYRIGDFVDISRGPLMSTTGLLGRCTITALHPLRELTNVSDTLYRMQGVALPAGFLLNYFAYGLIEQRGRLLNSARIPGSLQPHKHISAKHSPNQKTPLIEDEQKQAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5H5</accession>
    <name>A0A1D2N5H5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat domain-containing protein 54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_06236</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000206">
        <property type="protein sequence ID" value="ODN00472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5H5"/>
    <dbReference type="STRING" id="48709.A0A1D2N5H5"/>
    <dbReference type="OMA" id="IAACKGF"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070531">
        <property type="term" value="C:BRCA1-A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031436">
        <property type="term" value="C:BRCA1-BARD1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="401"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="650" mass="70509" checksum="B6375DC2347B3273" modified="2016-11-30" version="1">MAMITGGGDSGVETEGSNDLDIVNVNVINEQGDPILDLPDSGPSSSESDLNQQLGAAGSSFLGPDGGPSILLGIKDKGDDPPPPPPPTSPNICAGGNGLPEFLDTPVVQNFSSDSLDGMIDETEEELRPNIEQSGVVNMEPVLSSHVQPMPVIEDEVMERDELSDEEDHSRNIRNIINHERPHNGGFASPSKRFLSDIPEPDFAECASEDGFAHRYPYSFSSTVDLSFSGSGESSAFSYARPRAMSDSFHPTSSSVFHHPHPPPAPPVTPTNMNNCRALVKFEFPELPKLVCQFEPPAGLRSFMSIQPFQNDNQGGYTVLNSAPSASDCRALIPYEQKDLNQKVRSQSFSRKTRNKLYDNWANIRKEYNEKRLRTAAGAGSFTMVQKLLTVDIDPNAADELGRTALHIAACKGFSDIVSLLLSSGANPNARDCVGNTPLHLAACTNHFDVVTCLLRAGTDVSTLDNNGRNPLQLAQSKLKLLANWKSDSDDALKIKNEVRQIVEMILEYLQKKGQDMEAELLNDFANRLTLSQTAEEVDADVKNLLANLSSLTINVGSAHATSNPIRIPPKNPYLNATFNPNLARPRSLNSSPTSSTVLASSSGSTSIIAPARFAMKSPLAPCDATREQKQLICNLNRRRAESEKSREPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6Q8</accession>
    <name>A0A1D2N6Q8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000181">
        <property type="protein sequence ID" value="ODN00912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6Q8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="272" mass="30175" checksum="C635DDF25382D2F7" modified="2016-11-30" version="1">MSEKENKTLPVALLVTGIVCIMILSCCFVWLVVRCERWRRRRKYRPKHTNRYKINASHIANGQELKDLEPRHLNPSVNLIHYASKNSVTSQSIPSLLSADSMDDSIASEPLYARNYGEDEPDSDYLPARDLSIARILGSFPELKFYPPSASSSAENVLDAKNDKPPIPIPRPRASATETVPKSKDFSINSSLYTDCNSKASIDSFKGSAKSGSSAESLGVQMPGGKLKIHDISGNFEFTKVKSRKDKSSSLLNDSETNPQMKVPRIVLETEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N730</accession>
    <name>A0A1D2N730_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposable element P transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000174">
        <property type="protein sequence ID" value="ODN01064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N730"/>
    <dbReference type="OrthoDB" id="7440550at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048366">
        <property type="entry name" value="TNP-like_GBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048367">
        <property type="entry name" value="TNP-like_RNaseH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47577:SF2">
        <property type="entry name" value="THAP DOMAIN CONTAINING 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47577">
        <property type="entry name" value="THAP DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21788">
        <property type="entry name" value="TNP-like_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21789">
        <property type="entry name" value="TNP-like_RNaseH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposable element P transposase-like GTP-binding insertion" evidence="1">
        <location>
            <begin position="145"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Transposable element P transposase-like RNase H C-terminal" evidence="2">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="375" mass="42278" checksum="13D5221811E530A6" modified="2016-11-30" version="1">MAISFEKMTKKFKGYIDYAEFSEYAKERKSPKCEADHCLVFLIPFFLNSKITQPIACFATRGAAPGNILAKMLLVSCLMEAATNKSMWRELGITTKRGSGIVNSITNPVDEGRQVFFSAIFLTFLNVLEITSTIRKTSRFKDSTQTYTKRHCSRPIQKMSVASAAHVFSKSTANGLKAYREISQNSFFQKSEPTENFTRLLNDLFDACNGRIPMDGLRPENAKYKIIEDFLAAMSPSDTYASDQTFVSLQVTLTSLLELTHYLCNVIGYHYVLAGKCNQDPLEKFFGLVRSFGGNDCHPTATSFSHIFRLLSVYFPTSRSIKGNVSKDEEYAVVSVSCIDTLKCLRNVAKTEQERNNKLLEDTILSKIFYSQDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7E9</accession>
    <name>A0A1D2N7E9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">[histone H3]-lysine(27) N-trimethyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.356</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_05524</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60292"/>
            <dbReference type="Rhea" id="RHEA-COMP:15535"/>
            <dbReference type="Rhea" id="RHEA-COMP:15548"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.356"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.356" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000168">
        <property type="protein sequence ID" value="ODN01184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7E9"/>
    <dbReference type="STRING" id="48709.A0A1D2N7E9"/>
    <dbReference type="OMA" id="CNILCED"/>
    <dbReference type="OrthoDB" id="6141102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035098">
        <property type="term" value="C:ESC/E(Z) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140951">
        <property type="term" value="F:histone H3K27 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19218">
        <property type="entry name" value="SET_EZH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000001">
        <property type="entry name" value="Putative histone-lysine N-methyltransferase EZH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026489">
        <property type="entry name" value="CXC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045318">
        <property type="entry name" value="EZH1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048358">
        <property type="entry name" value="EZH1/2_MCSS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044439">
        <property type="entry name" value="EZH2_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041343">
        <property type="entry name" value="PRC2_HTH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21358">
        <property type="entry name" value="Ezh2_MCSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18118">
        <property type="entry name" value="PRC2_HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51633">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CXC" evidence="10">
        <location>
            <begin position="797"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="894"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="397"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="579"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="625"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN01184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1028" mass="113577" checksum="E6797D19F9F9D121" modified="2016-11-30" version="1">MVSSRRSWVVEELSRKKKDYTRGHHTQTPKWMSSGAGNRGRNGRVPHWASNAAKNQLHSLSLTKHKTGANGTVAGANNGKSSSKSGANSSTSSSTSNSQGGKKKGDDNGTESKRQTPGKSGAAKSQNGSTTSSPVTRKSLHDNEPPKRNKRKLSVECPMEQPRSKKISISNAAANGSSSNSHNASSSNSISNANNGNGSVGGSPPPPPSAMEAIKKRVKPEYIRLVQQKRQRRSYDAKLAWNQNIKHINGMLETEEQAWKGSKGSTWACKTVKEMVADGESSHLASSVVKRALVTSHDMSPQECPIITIHSIRALPNMYTWAPLSENIMVEDETVLHNIPYMGEEVLDHDGKFIEELLRNYDGKVHGDDDKNFIDDEVYVELVRTLNSLYEKQVGSKAGQITSSPAGKGKRGENKDASFESGSKSPTKKEPEQGMIITVGNTVTSTKVKVPPMVVFKAIAEIYPEKGTPTSLKEKFVEVIEKLEPGAGTSADCTPNIDGPNAESVSREQTMHSYHTLFCRRCFKYDCFLHRLKTDHPGPGRTNKRKYNEFRAVKSCGPTCFLNLPEVKAKLQAVALRNAELEQSESGDRSNDSRPKKIRKHTSVDSSNDCSDAEDSNDSFKVISNRRSGSTSTTNGHDQRKSGNQSSNSNSMNGHHSAGTSEKPQTFALSDLIKAFSQDNTKSSSSTKPSSAASTIVNGQINQISESSLGPSFLQDFHMDVHDGWSGADQSLFRVIHKVHLTNYCAIARMLLTKTCQEVYYFAQKEAADELTDETSGEQTPPRKKAKKKNRLWSLHCRKIQLKKDDSSSHVYNYTPCDHPGQPCDKNCSCVSAQNFCEKFCLCDPSVRTDFQDVGVKHSVIRNSVRAIWRFGADSYDTTSINCKNVCAQRALHKHLLMAPSDVAGWGIFLKEGAQKNEFISEYCGEVITQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRTIQPGEELFFDYRYGPTEQLKFVGIEREVDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9D5</accession>
    <name>A0A1D2N9D5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Locomotion-related protein Hikaru genki</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04821</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000136">
        <property type="protein sequence ID" value="ODN01862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9D5"/>
    <dbReference type="STRING" id="48709.A0A1D2N9D5"/>
    <dbReference type="OMA" id="NDAPECI"/>
    <dbReference type="OrthoDB" id="5804959at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050350">
        <property type="entry name" value="Compl-Cell_Adhes-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19325">
        <property type="entry name" value="COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19325:SF575">
        <property type="entry name" value="LOCOMOTION-RELATED PROTEIN HIKARU GENKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="13"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="151"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="218"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="283"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="645"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="731"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="783"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="856"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="673"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="753"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="886"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN01862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="921" mass="101856" checksum="DA3B92EA7F88AD06" modified="2016-11-30" version="1">MQTIVNNVFLVSVYCDAPGSVENGKALLVGDLGLYDYRNQLQRFMHNQKVIFECDEGFTLIDGPQEKICRNGLWFPAVSEPKCVFSDTPGFRWMQANRVKRRAIKSGGTGSLARSKVSGGGGGGSGGNKRRGKKGGNMGEEEEGGETDELEMCPSLAEEPYIEIEVIRPGSDPNNTDVSEGAALKVSCTHGFGVNLQNDTIVCDKGRWRPKFPLCAALPCKVPYISHGTFYLGGKALFFLEMKVHTSNIELRCSRGYVLKGPNRFHCWYGEWDVNDAPECIPASCELPQLDRGSYGSRYRAAMVVGHGTEVDYHCDGEFQKMAPGGPAKCHLGDWRPNKPACFHPSYIHGMINFTHDKDNRLITSIKRACGIPQKEKGAIFYVEGKPIDYDSDYIFPDGTEVMYRCAAAKPKPRNRWKMVCEDGQWIGGTQNLTCEMNATIAANITSAKDVIRMINSTCTYRKKETHVVTFYNDLQLTMDSQEFPPGSVLINRCIDIGKFVLRGAVRRKCISGQWLGITPKCEGLSQYYDYVVDKPPTILFRYLNGSIVQTNDGKLMVYPGTTLHMECLYIRKFGRPHWNVSNSQPQPNNPRVYPEGWTDGIENRDPTLEYRLTIEEAVEDDSGSFNCITPSRHGHEIDIIVKKVDCSPLPDRPDLLYSTDSTMLGTKVSFQCKDPNSLIGAKEIVCQSTGSWSAPLPKCENVECPDISMVPAMAPLDYTSVTRNGTLKRNETAPPKITILSREVGGKVTFSCAQGYMVEGVSDAVCQSSGDWSSAIPLCKEVECSPPPSPQNGYVTGNAPYKAGDLAQFECRQGYMMEGQPIIACQDNGMWSRASSTTKCNNSLLFNAHFTKRVKACTYPGTTIGGTISAVKFYYPIGETVEFDCTEGYDLQGSRMLHCLDTAKWSTSIPNCVSRDGNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9V5</accession>
    <name>A0A1D2N9V5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000127">
        <property type="protein sequence ID" value="ODN02034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9V5"/>
    <dbReference type="OMA" id="AGIGHGH"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="14190" checksum="8ACAC00E23281641" modified="2016-11-30" version="1" fragment="single">DRKSIPFSTFLESLYKLNSFLDFSITTYSKLQQQTIQLIFSDILSTTTTMYKLAFVALLALAAVVVAKEAEKKDLETSATGFYGGYGGLYGGGLGGIGYGGYGGYGGLGLGMAAWPGWGGYGLGVYYGGYGGIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBM4</accession>
    <name>A0A1D2NBM4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Apoptotic protease-activating factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_04050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000102">
        <property type="protein sequence ID" value="ODN02648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NBM4"/>
    <dbReference type="OMA" id="CHIFFGH"/>
    <dbReference type="OrthoDB" id="1357022at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01671">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041452">
        <property type="entry name" value="APAF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001315">
        <property type="entry name" value="CARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048975">
        <property type="entry name" value="WHD_APAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22845">
        <property type="entry name" value="APOPTOTIC PROTEASE-ACTIVATING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22845:SF5">
        <property type="entry name" value="APOPTOTIC PROTEASE-ACTIVATING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17908">
        <property type="entry name" value="APAF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00619">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21296">
        <property type="entry name" value="WHD_APAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50209">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CARD" evidence="6">
        <location>
            <begin position="16"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1032"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1308"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1396"/>
            <end position="1425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN02648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1476" mass="167185" checksum="6DAD9BD28AB98E2A" modified="2016-11-30" version="1">MSLLDEQEIARQITSLLKCRKAIVADLDVHDVMPELLSKFVISHADKQRIDHEKSAEDKADKLLTVLEEKAQKTLNVDIIPAFTQCLQQKYDWLYSRLTEDVTDATPATCFHLESRFQKLLSGGVVSEVFKDDHGRFTTPSGKRIKALLESGGVPCLPAVAVEREEILNDVRQELETLKRNQYLVICGMAGSGKTVLGIQAVSDETLVSSKFQDGVFWLAIGKECSESKDALLSKMRILCDKLGESKAPNSIEHGVDILRTAFMKRSDSLLVLDDVWRAEVIRYFDIGCRTLVTTRDLAVMDVVNGRVKYFQVKEGFNKEESLRLFAQALRIKDPETLPKEAYEIHCQCKGSPMVISLISSLMQDHQIADSGRWAYYLESLSKRKYSKMRKARSYEHESIVDAISLSIESLSDTYRNYYYDFALFQDDVGIPCAVLMTLWNLKRYEVEDIMKDFVRKSMAVEEYDSNKKTYYYSIHDLQLDYLKYQLIADSKCEKDLHERLMNRYIEVCSSEFHKLPDDGYAFFYLGYHIYKSGFHHLFPTIYLDLQFIGEKIRVTGPADLLVDIKKYFDFIVCEREERLKLIEEIQTFAQLEGHKIYGQLDVDIIQIALQAPYLQRVHEQAKKLARASPNRLYIEWTDHVVCAKFVGSGGNHFIAGLHNGTIQLCDLESSAVCHIFFGHTDTVNSIQAMKLNACFRKNGVVQTATEDRLVFLSASADKTCKMWDLQSVLEEVELLSAELKSGRLLGTSPSPKLRPDHWNFEHKRDDSYFTFEFHSASVTNAEFAMDGNRVVSTSLNEIIVWDSSNGSVVFKISPCFDAFPQLTYQLCRVPPEKYPSYLICSAENQLVLLSPQRSTVYSSVEGHTMRIVDLIFLSADRFCSISENDIGIWKVIKNYPKGKTFRSRSLSPSRCVPPSIINGKLELPHKTSNLLQPLDMNLLMTTSITSTDSGGKSPGSKSDCAPSSTNTLVQIDDGNITITAIRDDILPKKGNGNYLCAAIVKNNEKFLLACGTSDHKIAIWELTARKFLGSFTSHNGWVTCLDFSAVDICTLLSGSEDHCVMVWDIEEEERGTKEPQKHSKFTSSFHESGAHKSHFISAFISERNTIQVYRDYKRLFETAQFDFEITATALSPSTSSSCYVVVGTTIGKIYRILFPAFSTSVGGTPEKKIDLDIKQIGTHNLRITLLQIDPSGQFLISGAADGSFMVFMNFMLIRHVSFSHRPICGIHFPFADSIFIVCSQDGNMRMFDAVDSDSPEFQYVRAPGEKHITCTEVSSDGTQVAFGTTEDGIVLFSLDKYVGILCYKILNCHHKSPVRSLAFDAFGTKLAVGHDNGLITIWKGEGEMFYEETDLVLHKSWIRKMRFSPSHVSNSKWLITCGDKLVFWSLEKPEEKHRRTSFMSERRRRRSGESPSKSNNRLSLEIPTGSKIGRQGKRELLQQFSFRGNFAQNFESDLNFTKVITVDDTGVFYVLESMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC07</accession>
    <name>A0A1D2NC07_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase [NADP(+)]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC07"/>
    <dbReference type="STRING" id="48709.A0A1D2NC07"/>
    <dbReference type="OMA" id="AGHEREN"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="176" mass="20121" checksum="AAB16F27282CB86A" modified="2016-11-30" version="1">MTNPQQDQLALEQTLNVGYRHLDTAYKYENEELLPWIGMQADKVDHFINLSLSKLQTEYIDLYLVCWPFGMNYRGDDNVTPKKDYGDLDLDLTTDLLAVWKAMERQVDVGKAKAIGVSNFNSQQIERVMKISRDGYPNLWYQVQSIINCQFLTGLQSLQKKIIITASPAPPTLCIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC82</accession>
    <name>A0A1D2NC82_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Troponin I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_03808</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the troponin I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000093">
        <property type="protein sequence ID" value="ODN02862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC82"/>
    <dbReference type="STRING" id="48709.A0A1D2NC82"/>
    <dbReference type="OMA" id="MLQVAKH"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005861">
        <property type="term" value="C:troponin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006936">
        <property type="term" value="P:muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.350:FF:000004">
        <property type="entry name" value="WupA, isoform I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001978">
        <property type="entry name" value="Troponin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050875">
        <property type="entry name" value="Troponin_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038077">
        <property type="entry name" value="Troponin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13738">
        <property type="entry name" value="TROPONIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13738:SF1">
        <property type="entry name" value="TROPONIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00992">
        <property type="entry name" value="Troponin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90250">
        <property type="entry name" value="Troponin coil-coiled subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="32"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00074692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN02862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="22450" checksum="F898F5803CEA5418" modified="2016-11-30" version="1">MQRRPRSELGSSSSAAAKKGKKGFMTPERKKKLRLLLRRKAAEELKKEQERKAAERRRIIEERCGKAKNLDDASEDELRAACTEYKAKVDELESLKWDLEYETLRKEAQINELNIQVNDLRGKFVKPTLKKVSKYENKFAKLQKKAAEFNFRNQLKQVKKKEFTMDEEGKDKDGKEKPDWSKGKKEGEVEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCD9</accession>
    <name>A0A1D2NCD9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000101">
        <property type="protein sequence ID" value="ODN02666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCD9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="399" mass="42946" checksum="9D091DAA296D2BF2" modified="2016-11-30" version="1">MSHLWTGGYPRNTSNGDYGRFLFASNQNSSNNNQGNFTVYPSADGNRMVHHAHYPNCPNRQNGNGQPKVTGGGGSTGMPEYTIEYGEDAVRAALGGNMPDFQAQFMQQMNNGANQSSNGVAVDPQQIQMMNNGKSRVAMIPVVFDNGGGDDDDQQQSNEGSAESMKASVGGSGNNSNSSGQESNANVPQTSDGGIARAQAQSVKPPKKESIIDAYNSVRKVRSTGQVKYGRHIRPSYFNPQVPNPCRKKMGGGDFLPELPKCSDEPQGMPAMPPASDMNIADGNGMKVMMMENSNNNNCYTTPPKNLPQPYGMQQGVQPPPQRARSMPLKKHSRPTNSLCGKCTKCKNLSSNQNLGEPQVMTFPAYSPGTRRSVGSRNLTSSNLGQSAKNFRAIRFSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDS6</accession>
    <name>A0A1D2NDS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000075">
        <property type="protein sequence ID" value="ODN03418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDS6"/>
    <dbReference type="STRING" id="48709.A0A1D2NDS6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="13331" checksum="010724CDF419CBF7" modified="2016-11-30" version="1" fragment="single">GRVNSMPSQPVSAMSSKLCRQVSIESPGPLLKDCVFSFDVPVPDVPPTGARIRVSGFSHGPAFGCLLVGTGGLALWALRLAQYYLKDVKDRVLLVVACLRDEGILLAKEAANVDVSNGTKTVTNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEN7</accession>
    <name>A0A1D2NEN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000065">
        <property type="protein sequence ID" value="ODN03721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEN7"/>
    <dbReference type="STRING" id="48709.A0A1D2NEN7"/>
    <dbReference type="OMA" id="EYDDSEW"/>
    <dbReference type="OrthoDB" id="7701370at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040010">
        <property type="entry name" value="ZN608/ZN609"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21564">
        <property type="entry name" value="BRAKELESS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21564:SF5">
        <property type="entry name" value="SCRIBBLER, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="490" mass="49538" checksum="A12D69E1496FB525" modified="2016-11-30" version="1">MNEVGGSESGTGLRAIKSSRSSDANFEYDDSEWDVGIGNLIIDLDADIEKNNEANRNNNNSSSSNLSTSGTGALPGPGSTTSTTPPSNTNSNLSGTTSNTGSSNPQMHITLSSSGNSSNNSNSGSGNSKGSKVGSGGSSSLSKGNTSSSSSSSSADLSSVMEHSSIVDKGLKMKIKRTKTGAKSDAKHEIVKNDVVGSSNGTSGGGSSGGGSGGSGYNKSLPENLSSKNSHSSHKDKDKLLIKDGLLHDNSLDSGSINNATSGKQVDNSGDHGGKVKTPRKGSTKEKKVKNSGSAVGNSGNGKKDDKNADSKSLSNSNSGNNTSSSGSSGTHAKDNKEFFSTTVNLNVPNVIPNSSSSAFVKATATIKVPTAPSSSAASVLSSSGSGLHNVHASGDSSSSSSSSSSNSRAQNLSTTNNSANNSNNTPWGTVSPTKGADKGRLSPSVANLSNASDKTQGNSYNKKARTFTAADKVCLFTLYKLPHFIILPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF15</accession>
    <name>A0A1D2NF15_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aquaporin AQPAn.G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02831</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000061">
        <property type="protein sequence ID" value="ODN03843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF15"/>
    <dbReference type="STRING" id="48709.A0A1D2NF15"/>
    <dbReference type="OMA" id="ICVVFIC"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="289" mass="30746" checksum="FB21F0A699881CD3" modified="2016-11-30" version="1">MNPGKLDGFKPGLDLLNMGRMQDLKERMGADRMKINEKALWKCLGSEFLGTAILMFLGIGCVLKLEHEATKQLSFVGVALCWGFTVATCAQALGGVSCDINPAVTLACAVAGKIPIVKALMYVLIQCLGALAGTSLLKAITPDDVVGDWGITALAPGITPIQGFTIEVISTFILVLTVFSVNDENRTDVKGSVPLAIGLCVASLVMCSGPFTGASLNPARSLAPSIIAGHFDNHWLYWLGPITGACSASLLYTYVFRALRPDEIEKLEAEMQLKQREQEAKEAGGNPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFP3</accession>
    <name>A0A1D2NFP3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02894</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000064">
        <property type="protein sequence ID" value="ODN03786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFP3"/>
    <dbReference type="STRING" id="48709.A0A1D2NFP3"/>
    <dbReference type="OMA" id="STCQARH"/>
    <dbReference type="OrthoDB" id="245173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="604" mass="69350" checksum="AA6D22E8672EA201" modified="2016-11-30" version="1">MSLHALQEADKWTSLAKEIEQLLDAGDVTKSYECIVGMEKSLLVLDQATMDERRLILEEMKNRLEALATNHLIHAFDTNDTERAQSFYHMFVNLERTEQFVKYFQNSEKIKLAQEWRNSVELLPFKEAILKLYDGLMDHLQLKLNWCRTIFSEDQVGRSVDVLVDLYSELLMSLEPTVQYCFEVETRKEPFIELLLHFNQNTMRFIENFLHYTEMNGEKPNSMKFKTLSNTLLSPFFQQYSRYSKYHETQVINKIQAVIAVVLGITTSTVDLTTALQEKIESSKRLLPELILSIKEGEEKVQLFNRGAGYYHFSRGINAGLERFAEWNQEIYRSLDKSVKNSDRHRNLLEINLSFTETCGEILLQISKLDQTLTANCHKALSLVLSKDSDTSSYEIWDCLLNAQIKTEVVQFFEKKNTLLGNACNNFKKLCRDATQLVLKVTSEPVESQFIKSFVLQDSNLKDVIPSEYITQVGEYLMLLPQNLDPFLTENSSLSFAFDQNSDEGGRSPLDFLLSNLAIHICEVYGNRILKISDMSNGQARQLAQDIDYLSSVMDDLGVKMTSDLVDLGKLTKMFPEITDGTTVDRVSPRLLAVVKKMKTKSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGA8</accession>
    <name>A0A1D2NGA8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Melanoma-associated antigen 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGA8"/>
    <dbReference type="OMA" id="HFANRTQ"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="377" mass="42727" checksum="9C6186556737940C" modified="2016-11-30" version="1" fragment="single">NKFTAVFLCFLFAVFPLLYTLSGFQVIPSSVLWNPSLMFRCLVVEGRFAFFLNVTSREPCNDNNPPALDELCLIDLIVGVLAFLMETARQVLGFYSDFFPLICCLSLWTSVGALQEYLEIEDNDYIHQHQHKHFHSPKVEEQRTSCNGNGRIMLPYIFPSSSVITSSTPTTSTPLPLPSTDEASSCQKEKIESSHSGFQSSLDSSEVGNILLERYEVCKAFSRTVNRALGQLLFAYVLSSIMYLSTCMDAVLVLQDWFGKLRVAFFFFVFILMFFIGSEIVNKVYGLRVWLSTPTNNAFLSERNLLVLIQELTCKSIGVSGNGMFTITYSTFMTVMTTTVTFFIIILQFQKPDREELSATLRTFMIHFANRTQLLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHN1</accession>
    <name>A0A1D2NHN1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHN1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="35550" checksum="E39BBDDC660E78D1" modified="2016-11-30" version="1" fragment="single">MLFAATRLCASQSTDCCNSSLVGVIISGHEVPRTWFDNSIKYAHFRDKLASHITYMGNTGSSNETLWNATLAGLNVLSNWGVKYWDSHFIRNNVFTQECATKIAQAAACGLCVTGTDNTQLNEIMNDLNLWREPISWWTEENNACELLPETNCWNGEAVGSYEFPVVRWRQSFNPEFTDKRGSAVNPNVMLQLDKFHNELIQVRKSLEKYWPTSGSDTRSVLSPMSLSSEEFIDGSGGYDDEDLEYVASGDGSYTTGVHSKPIDSDDEDLPGYDGSGSGEAEDPPAHPLDELPDEPRQPTESRPPVRLDNSAGGIRLNGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ30</accession>
    <name>A0A1D2NJ30_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Early growth response protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_01394</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EGR C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000026">
        <property type="protein sequence ID" value="ODN05270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ30"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ30"/>
    <dbReference type="OMA" id="NWILPSP"/>
    <dbReference type="OrthoDB" id="8197458at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000324">
        <property type="entry name" value="Early growth response protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000419">
        <property type="entry name" value="Early growth response protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050752">
        <property type="entry name" value="C2H2-ZF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24384:SF189">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24384">
        <property type="entry name" value="FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="301"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="370"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="392"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN05270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="482" mass="53266" checksum="9B4A0830CEA9D931" modified="2016-11-30" version="1">MGSLDSDLTLSSHNSTPASSPPSSPKMFPSHPSHHQPMDEAQQQQQQQSQQQHPHHQPQHQHPQQRLRVTMPTVTQQSSLNTPLPQSAGSPTSGINWILPSPDRSFYGPLFGILTPTSQPQQLSFSSDPQSAGASQFSSHSEFNFDPCILTDDPFRQQPPQSQQPPDQTPQQPQPPQQQQPPQQQQQQPQSSQPKYHPWATPEFEQTSQDQLPVIPKQEPFSEFCTGGPPSVETSSTQDASGGPASVGLAEYNPSTSKGHEILSQVLPEFSQQAGPLRLVPVKPRRYPNRPSKTPVHERPYACPVEGCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHVRTHTGEKPFSCDTCGRKFARSDEKKRHAKVHTKLRTRREKSSTSNASASSTVTSASAATGAPAPSPSSSVTPVHMLASPQQPATPQQHQLHHLGASTQQQQQQQQQQQQRLAQSSLPHTITSEDLPIVTSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJY2</accession>
    <name>A0A1D2NJY2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01256</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJY2"/>
    <dbReference type="STRING" id="48709.A0A1D2NJY2"/>
    <dbReference type="OMA" id="MERTVIA"/>
    <dbReference type="OrthoDB" id="6351660at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034451">
        <property type="term" value="C:centriolar satellite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097711">
        <property type="term" value="P:ciliary basal body-plasma membrane docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905349">
        <property type="term" value="P:ciliary transition zone assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026201">
        <property type="entry name" value="Cep290"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18879">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 290 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18879:SF20">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 290 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="17"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="155"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="297"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN05415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="472" mass="54373" checksum="808D7EAACC98CDCA" modified="2016-11-30" version="1" fragment="single">ISSLQLRLSKTKAVNYKSGVSTELEELRIKYRDLQDEKLKLEKDIHELNSKRDEEEVKKIKTSESVARWEESKKWKKNKEKMESRVHELELENEKLEKLVTALKTSIHRLEKEKMILDTRLRSRHSLHGSSLSKSSLDNISEGSAPSGATYHQSYILAQGEIAKLQLELQDTKELVEKTEFEGREEIEKLKMEIKCLKERIVTQERLLTAYEVAQKGDPQVVQEIQKMAAHESEFQKEIIRLEEENLHLRLQMEQLQLETPRLRDRVQHLQKIVDALKTEKLPGRPGSVKSVAQRPLGELERTISALKQVIDKLQVENQKLKGSRGDMMGGSVPRAISSERLKSSVSALMDEKRTLLDRVQSLEQETEKFQRMYMEKCTVVDSYENRLQDAEKRAKSTEMKLKAFLDDRKTTSPHREAAGSSSSTCHNFDALTFKVQKMEEELLHKSKILTTAKQALHDAERFAATKSGTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKG5</accession>
    <name>A0A1D2NKG5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Exostosin-2</fullName>
            <ecNumber evidence="6">2.4.1.224</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_00977</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.224" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKG5"/>
    <dbReference type="STRING" id="48709.A0A1D2NKG5"/>
    <dbReference type="OMA" id="AKILVIW"/>
    <dbReference type="OrthoDB" id="5954868at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050508">
        <property type="term" value="F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015012">
        <property type="term" value="P:heparan sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000035">
        <property type="entry name" value="Putative Exostosin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015338">
        <property type="entry name" value="GT64_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261">
        <property type="entry name" value="ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48261:SF5">
        <property type="entry name" value="EXOSTOSIN GLYCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09258">
        <property type="entry name" value="Glyco_transf_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="18" id="KW-0464">Manganese</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Exostosin GT47" evidence="20">
        <location>
            <begin position="127"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 64" evidence="21">
        <location>
            <begin position="479"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00069568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF09258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODN05712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="742" mass="84994" checksum="F34CC08791DDF910" modified="2016-11-30" version="1">MLLLIVGAVLAYLLYFLPSYPPVNLISYHKYQQQQKASRQSAILSSSSSVEDATVANHFQDLQLVPLESAPVRHVSKGDLQNRQELLDNELEWALRAPRGGERGGTRSKCSMFTCFDIHRCGAHNGTLSVYIYPIYQWMVDGQLVQQSLSQEFYQFLMSIKKSPYYVPNPNDACIFVPTIDLLNLNKLTVSSEDVLAVLSSLEFWGNAGRNHVLLTMFPGNSPLLSLKTNAIIASAGLFVENYRLGFHVPVISPSPLVLNRASNTSKNAIGENQVRNSHWIAVAPQGAFTFDLLSSNSNDYSILFLDYCHNKDGTKMRNYSVRCSKYHQMYQYPDVLKEFDFCLVIRDLASPVLWEVMSVGCIPVIVADHQRLPFDEVIDWRRSSVQLYEHQMHQLSSIINSISESRRRRLKKQVKFIFDKYFSSMNQITMTLLTTLKDKVFSHYAMSIHEWNGIEGHGSSYVQPPLFNPIIAPRDSGFTAVILAYERVPSLFTVIQRVSQVPSLVKILVIWNNQLKDPPSLDSWPKVGIPVKIIRTKENKMSNRFIPYDEIETEAVFAVDDDIVMLTVDEMEFGFETWREYPDRIVGFPSRSHVWDNSTRRWKYESEWTSEISMVLTGAAFYHKFWHYAYTNELPRDIRDWVDAKMNCEDIAMNFLVSARTGKSPIKVTPRKKFKCPTCSNNEMLSADSGHMVERTECINRFTEIMGFMPLIPTEFRADPVLFKVDGVPGKLKRYHDMGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL34</accession>
    <name>A0A1D2NL34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL34"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="99" mass="10934" checksum="FF184E2F8CE4FA5C" modified="2016-11-30" version="1">MDKSAFGRNGAMNNTMILPVFLIGSALFFAAVNYAFERFIEDGKENSFDNPLQCLPLPTEEYAEGEAALDDMLILEINHNSIKLNMSDVEPEGIGGFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL63</accession>
    <name>A0A1D2NL63_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="10">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_00687</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The RING-type zinc finger domain is essential for ubiquitin ligase activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the SINA (Seven in absentia) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN06010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL63"/>
    <dbReference type="STRING" id="48709.A0A1D2NL63"/>
    <dbReference type="OrthoDB" id="8182903at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018121">
        <property type="entry name" value="7-in-absentia-prot_TRAF-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004162">
        <property type="entry name" value="SINA-like_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049548">
        <property type="entry name" value="Sina-like_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013010">
        <property type="entry name" value="Znf_SIAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45877">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SIAH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45877:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21362">
        <property type="entry name" value="Sina_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03145">
        <property type="entry name" value="Sina_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21361">
        <property type="entry name" value="Sina_ZnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51081">
        <property type="entry name" value="ZF_SIAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SIAH-type" evidence="12">
        <location>
            <begin position="39"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="SIAH-type" evidence="12">
        <location>
            <begin position="414"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="630"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="667"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="700"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="740"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="787"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU201113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN06010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="964" mass="107342" checksum="5EBCCD8C40F2C082" modified="2016-11-30" version="1">MSTGHNICYLCVDEVSECPLCKSDYGDTRNYFAEELVNSMTFPCKYEEYGCHQTFLGSELKEHQENCECQPYRCPELACQEVVGIHQMGKHLDKHGFKIMTGDVHQASVEILDDHFDRKTEYNPWRITAFGAEFYTVSTRSRDGLWYFWAYGLGLQKDMKKFSYEVVLYSDEKQVMYRGAVQSLRNAPEDIMKNGSCLITTDNMIKSIRKNGRIKCQVYFIHGKNWDQVRSNLVAGKGKSKQALKNLKKHPITKGKNKVLIPTSVTYTCPSTSSSSPMPSLLSTPKTSRSRVLHNNIKASAMDLLKKEQSSISAVLGSGSGSSRNKLTKSKRTASNVSTTNRNTISEDENTFVQKVRDTLRCPGCNEVITPPVYQCLIGHNVCHKCKTTRQDCALCRAPIGECRNFFAEELLYKTFQRCPYSKHGCKVCLPSAHMRSHEAICEFAPFECPFNVCRAMLCAEELFDHLQTHQIAVISKELKTEIVVPRNAPTMPICTIPNIITIDKIPFYPIVVRDTDGSWLFYIISHNHSKYRYELLIKKQSKTIAFQGPVQSIRTNFTQVKQKGTALIATERTVKCFKSHDKLSYHIKISKVDAVPSDTTSSFCLPISWILVSRKGELVSKTELFANKKTSVSPDEDSDGDDTTVSLPRNDPAIYISEAEDFETESGATSEMETSTRASTIRDEESEYESDNLNNNRTDGNETQKEETNASEAGSLTSESSPTKEKPVDESNYEDLPELSAGSSGLSRSAASVHNLSLAKEESASAPSVPISEHNSDLITDANKDKTKRSRSVTKNRVRLSQDVICCINDGTDPLFSRCKGPSKSQANLHSSPSRLTAMAMKASKHMLSSATWAEDEDKTPPAPASSVVNEFDQLKQALEKLSKEGKQNAVDDDMPVMEEVGDLLTVKSLNGMSEAISAVNDAVISGSFDVVKSVISLFTSDKKEIDKTAENSSENLGSDERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1N1</accession>
    <name>A0A1D2M1N1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ZP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006920">
        <property type="protein sequence ID" value="ODM86875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1N1"/>
    <dbReference type="STRING" id="48709.A0A1D2M1N1"/>
    <dbReference type="OrthoDB" id="6139674at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13543" checksum="CFFD7DB4BEEE1FD6" modified="2016-11-30" version="1">MTTSSQDLEEEEYFNTIVLEPHPKLVTGQGRGFQVRCRYRKHEPANMPPVSMKIFKNNLQINGGAEDEPELTNGTNAVDRSINIGDPLQIRIQVHANTTHNFIVTNCLVRDGLGWQKKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1Y3</accession>
    <name>A0A1D2M1Y3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19718</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006605">
        <property type="protein sequence ID" value="ODM86964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1Y3"/>
    <dbReference type="STRING" id="48709.A0A1D2M1Y3"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408:SF58">
        <property type="entry name" value="TRANSCRIPTION FACTOR (TFIIIA), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="258"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM86964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="36944" checksum="E639F37DA5132715" modified="2016-11-30" version="1">MTLTVDSTTISGNVKRKKKSNASRPIQPTTKKFSSWSDCNNHFNQAHDSLWPCEICKRVFKAKDKLAKHEQIHSELKQFVCVICEHRYRTLPNLMSHISSLHTQEKPFPCTECPAEFALSSSLRSHIIRAHRKGEWVNKCFVCDKKFSTQQVLYRHLQTHTGERPYICSHSGCNKNFPTQGELRRHLSFHIGDKKYTGSVCGKKFVTNGTRNQHVKTHNKNSPQHSTSKNTRKAIQIYFEMGQLNKHVRQFHKNIRQFPCSMCDKSFYRAYLRDNHLSATHLNEKCEICDKRNRSSHQVTQPANRLKMCIMPQNVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M205</accession>
    <name>A0A1D2M205_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein sleepless</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006572">
        <property type="protein sequence ID" value="ODM86972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M205"/>
    <dbReference type="STRING" id="48709.A0A1D2M205"/>
    <dbReference type="OrthoDB" id="6249205at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="12073" checksum="ED1B3B4E608B6FCC" modified="2016-11-30" version="1" fragment="single">FKCIADEIITRNCLSQLEYSRHDVPADKYEGCRSAAKDIQLAHYVNNSIKQLDIRRDYYDEVTWCFCEFDHFCNGAIDINSFHSWTTTTLAVTAIHLVLYFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M346</accession>
    <name>A0A1D2M346_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hexosaminidase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005408">
        <property type="protein sequence ID" value="ODM87398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M346"/>
    <dbReference type="STRING" id="48709.A0A1D2M346"/>
    <dbReference type="OMA" id="GWANRYN"/>
    <dbReference type="OrthoDB" id="10023921at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015929">
        <property type="term" value="F:hexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038901">
        <property type="entry name" value="HEXDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040:SF8">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="538" mass="61501" checksum="EF2BE40A3E481E00" modified="2016-11-30" version="1" fragment="single">VLRLAKRSGINGLLLEWEDTFLGKVTSQIYPYREEAEEIVAYAERTLGLEVIPLVQTFGHVEFVLKMEQFRHLENWKEIPKHFVLQKVERLFWICHKNSKLIHIGCDEVYTCASDYRDELFLKHVIDVASYVRSKARIPIIWDDMLRSIPIRKLNDSGIGQLVEPMVWVYAEDVDRFVGWESWEKYAEVFPTIWAAAAFKGAFGETLSIPPAMLIMFKGGLMYSHGNHPSGLMVLTGWMRYDHFSVLCELLPGAVPSLVYTSLTLSTHRARSLEATTISPSSSSSSIAPIPSGSNNNEILSSSSVTSSSLSSSSNNGLDPISITTDDPLSQPSPRIFRRSARNFRSIPHPRILMANRDGFSNQRLHAREIVTQPVIFDKGEIVSRLFEEILVCPNHPQQIFRVRSLLDDIWELEAKISRKRGWVTPYNIRHNYSLPLRVDEVVFSQVPRLQRHLVILANSVVNSLKPIFPTETILEWIEQNMWEAWKALDKLEKAGDTLRNIQVWPRRPVPSPQKMVDDLRLTALDDSENTVDTELKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3J5</accession>
    <name>A0A1D2M3J5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOB kinase activator-like 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005106">
        <property type="protein sequence ID" value="ODM87526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3J5"/>
    <dbReference type="STRING" id="48709.A0A1D2M3J5"/>
    <dbReference type="OMA" id="QRFTKFV"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="222" mass="25175" checksum="491BC893F6035F12" modified="2016-11-30" version="1" fragment="single">MTMSEVKVIVRRNRPGTKGAEFCKWPEEPFEEMDSTLARPFQHHCHSNPPETQDEEVWKYEHLRQFCMELNGLALLNNGSFLCAAHKSPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIRESSLGKLGSVCRRVYRIFSHAYFHHKTLFDDFEASSHLCRRFTSFVMKYNLMSRDNLIVPNMEDGAITTTTTTTTDAAPVATETTTKVTPPTGNTTESEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3R0</accession>
    <name>A0A1D2M3R0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004967">
        <property type="protein sequence ID" value="ODM87613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3R0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="79" mass="9023" checksum="10515FB4FFD7BC74" modified="2016-11-30" version="1">MRTRARANANRWPVPAVPKRRGNPWFLTSNADGEVNAGLTTKRRMQEEITAEEGVIGGMLEEVKTLEKKLQPIKPLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3U4</accession>
    <name>A0A1D2M3U4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005023">
        <property type="protein sequence ID" value="ODM87581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3U4"/>
    <dbReference type="STRING" id="48709.A0A1D2M3U4"/>
    <dbReference type="OMA" id="CTENIFA"/>
    <dbReference type="OrthoDB" id="6728421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="1">
        <location>
            <begin position="144"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="22610" checksum="9BAF37E170CBD354" modified="2016-11-30" version="1" fragment="single">MSIPVSLALDKLQGEFGVFMGSLVPTLIRVKAMITEVKEDSECCSKGYATAYLNGIEKRFGQIMKIDDKNPSDYFRWVDQDLHSKLKKQFVLRATAFVKKCSTTDTPVSQEDELDPFYDFGNSAITTMSNGKNDTAASIYKASMLSQYPTVEKMFRRYNTSLPSSAPVERVFSYAGMILSPKRTNLTDSNFEKLVLLKCNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M468</accession>
    <name>A0A1D2M468_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ERC protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_18912</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Presynapse</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004718">
        <property type="protein sequence ID" value="ODM87769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2M468"/>
    <dbReference type="OMA" id="ITNAMEQ"/>
    <dbReference type="OrthoDB" id="7554219at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048788">
        <property type="term" value="C:cytoskeleton of presynaptic active zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098882">
        <property type="term" value="F:structural constituent of presynaptic active zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007274">
        <property type="term" value="P:neuromuscular synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048167">
        <property type="term" value="P:regulation of synaptic plasticity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019323">
        <property type="entry name" value="ELKS/CAST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18861:SF0">
        <property type="entry name" value="BRUCHPILOT, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18861">
        <property type="entry name" value="ELKS/RAB6-INTERACTING/CAST PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10174">
        <property type="entry name" value="Cast"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0770">Synapse</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="161"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1147"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1444"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="358"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="460"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="946"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1030"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1152"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1444"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM87769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1500" mass="174616" checksum="12BD9A3C385B6907" modified="2016-11-30" version="1" fragment="single">IHQELQERAALSSRGWWELLCPAATAEPTRSPRSSDALDKLLITPLRGGTRSSLSISQRDRAPRTLLQQPAGAGGSRRVLLRLRLQEQVLHSAPSSQRASPTYYTQQRAVYGYGAQANAPAQGRYGTMMDEYGNTTGAAAGSAMMGNPAAATGAAGPVVVDDYHSSGGSNRQQTHHRSRSASRLNRYSNTAMPTAGLRSLRQFVLRRGPVDELLWGSAGWWTAPHGREPAPPAASVNIEPLAARFRTKRNVSQPVSDASDGNNYLTELQLQNSDLQRELANLKKELELTNQKLGSSMHSIKTFWSPELKKERPLRKEESARYSLLSDQLKLLNSENQVEKIVRLEEELRLRTLRGGASLEMQRQMEALITENEHLVREIRILRETIKEFELRLETQKQTLQARDESIKKLLEMLQAKGLGKEEDRAMIQQLQIIAQKQIDDLRLEIQKRDQEILSCTAKMKTLEEQQQDYQRHIAVLKESLCAKEEHYNMLQADVEELRTRIEEKNRIIEKKTNAALQAAQERNRMANEFNEMRDQTEIKDRKINVLQRKIENLEDLLKEKDNQVDMARARESIHDKEKQILQLREQRDRAEHEKHEERELHERDVGEYKLKVHSLESEIDKVNVRLDRALSEKERLESRLDQSQLELGKCKAELEKTQSEFGKNTIEWENHRKIVTKFELENDRLRTENERLIGDLERSQTTFGRNTLNTSQELERLQEKYDKNLSELRRSQAELRMTQSDYERVNAELTAVQDKIEKSQGEIYRLKAKLENSIVENDNLKEELDRNQMVLNRVQNEREKINFEYEKLKEEYDRNMSSMSKYQNQVDKHQKEFDKVQAEYDRLQEKHDKLVQENRRVNAERDKLAFELDNCSSQMDKLNSMHLRVQKEKENHQIEVDRVNDKLEHAQMLLSRLQKEKEACFLENNRLVEKIDLLSSQVSKNTRDKESYCAELEVLKDRLEKEKGAYGKILNDRDNLMSEVELLRDRVDKLSGQVKSYQDEKESNSTELDLVTQKYERCQSELFRVTSKLDACNTELDKITQSCSKLQMENAKLQDVFDRNSIQMSRWKEHEDKLREEVDRWRIEAEVAREKLDKGCASEARIEEETSRLKYELDQRINSEMQMTAELKKLRIEIEDLNREKAFLEKELSKSRTTPQTPQTGLPDPEMLSSLRQEVSSYKMKYDRVCSELTQLETSKHALEVQLRRLEEKGLATPAPQDLKNLNSALEQKSVEVEKYANLVESKNEQIKTLQNELRNLKSELECDKGDVGKLRGEIETNRTVIEKQSVDYKRLKEEYSKVIEEIKKSQELIAKAQGENQKLRTTYEEKANELARLKSLVDEKSNEISYKGKEQNKLQERLDRYKAQQDKYEKQMSKMEHEMMQLTSERDELVTQLEKSQELLVQFQKELNSRVQNNEENQHEVVGLRGKVQELDAEVQRLRKALDGEEAGRRDGRQDQGAEKTLEGVKSSSDNEVGRLKSIIMKLEQELENMRVRGSLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5Y9</accession>
    <name>A0A1D2M5Y9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MACPF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003654">
        <property type="protein sequence ID" value="ODM88389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5Y9"/>
    <dbReference type="OMA" id="RWFANFT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MACPF" evidence="1">
        <location>
            <begin position="182"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="MACPF" evidence="1">
        <location>
            <begin position="270"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="492" mass="56442" checksum="B6D48D9195B5B5EF" modified="2016-11-30" version="1">MPLCTAVIGCSHTVPDDEVPRWTEEDPHGYYTFYGEMTRKCVNTRHETFPNSIITTPQESSCVNLRPGLSIMQHGYAREAFPPVQDERRLRDIVFFFSCDANETKTIDGYQRPSEVKHLTPTPRTLGFKRLVSKPEMLKTFAEDVELTEKGNAYVVFLPILRLNLSQTITSAGYLAEQVEGHEVALQNLKPSTQLSREYRELQTPFESHIINYYKFVRNYGTDVIRRSTFGGRFQVLVTNERLVNEINVADEENLTTVDHLVNECIRMEKNSFTEVTLLVEGGPASSRNNIKEWQREVMTDPVPISPQLLPIHSFLKSFGTPEQKRGLEEMVKFENRNHDIRKLLFELKLLEQPHRLSSFLISLLHGEVNMVCPSKNVYSVVKDGIINPKNINFHMFHVTCTHTRYYSLTEEKDLIVSRKYKLIPGVCFSLAIKLTPCVKASMKLPDGVNCVYFFKQKECKGMSTTVKTEAEIVKAFNSYQLSFMLCPSLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M706</accession>
    <name>A0A1D2M706_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynamin-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_17936</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003251">
        <property type="protein sequence ID" value="ODM88746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M706"/>
    <dbReference type="STRING" id="48709.A0A1D2M706"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="3">
        <location>
            <begin position="66"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM88746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="626" mass="70707" checksum="4724F0275A09825E" modified="2016-11-30" version="1">MHPSSSPWLTMPKMSFPLTIRSLGIFPNASKPKSGLSSIMPDSRGLIELVNKLQKLFQVKWTWNTKNRVAQIVVVGSQSSGKSSVLDGLVGFSILPRGSGTVTKCPIIVQLITTDAGKEEEGIELQDFLEDGRSQDYDEVRAKIAALMERNGGAIVDAIIVRVYSPNVVTLTVVDLPGIKRIVSYGEPSDLDERIVSLSRKYINEKNAIILAVSPANYEICNSEGLLLAKEADPEGNRTIGVLTKLDLMDEGTDARGLLTGMSKDVQVKLGMIGVVNRSQKDIENNFTEKSFLSNNYGDLIGQNGVPFLRKRLNELLVQHIYKCLPELMEKLEDMLKQCNKQLAEIPNVMTETDKFLIQVLHRFENEIKKEIQGSPRTPEYHHLYGGIVIKDIFEKHFAKDMEAAEKTSDGSMTPCVCNNFYISTYGILLLDGTEANYFAVFRKLAQNQIHHIEGPALKCAERVYDEIMKIADRNLAEENDHAFKYFPELRQLFKRVINRILDGNLDEVKKQIIEYIRVQSSVVFSMDYKFLQEIADLRRKLEKELYVGDGENSSDNENEPGMVKLYFRWIKSHVQDYIPKLVADKLIIPFTNDAGFGVALKVSVMKDYKTLIQLPKTLWNVVKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8K2</accession>
    <name>A0A1D2M8K2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002765">
        <property type="protein sequence ID" value="ODM89262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8K2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="37" mass="4411" checksum="8F9A387863612FC0" modified="2016-11-30" version="1">MIHLMNVYQNDIFRTSSSGKQKQLINRFHSKIGLQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA42</accession>
    <name>A0A1D2MA42_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_16869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002346">
        <property type="protein sequence ID" value="ODM89811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA42"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM89811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="20404" checksum="683C2698626B8AE2" modified="2016-11-30" version="1">MGNVPSHPVVVGNSEGLSDSDPLPPGVSEGIAVEREVELGDNPTDDEEDEIEKEEVVVYLRNENPADPGEQSRLQERNEELTELLRFAGIRIVQLEFQRRQGENDLRQVELQWRQAELERDQTELRLLETRHQLNQVKIARIKDQINEIKANNRILWGFLAGLILGGAYMTLIMQIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAH5</accession>
    <name>A0A1D2MAH5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002249">
        <property type="protein sequence ID" value="ODM89995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAH5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="283" mass="31447" checksum="E01C3D263391CA69" modified="2016-11-30" version="1">MIASCLSSNPTAKMLSTLRIFYSFFISILLPIATTASYFESSGCVGQKLFNLQGSILYNSTFRNPQFGNTGKERCVWVLAAGQATYNLEYHVESVYGQDSALTGTCISSTGGNNITLSNFQMNGSQNLSVSCPVLIITYHTEMSSVVSSKSGFSLSWSTEGGAAENYSPQSSHYTRIVTSDLIHVRKSYENNELSTFIFVRDPRDLYSQMIVTYSPKDGHIEEADGLEGDCYDHLLVYRFEPLEGYVAFTDDQDLNQICVGMSDFYPSDEITLFVFRSDDSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBJ4</accession>
    <name>A0A1D2MBJ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002025">
        <property type="protein sequence ID" value="ODM90343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBJ4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="109" mass="11298" checksum="EEE292585C24FDEE" modified="2016-11-30" version="1">MRDSRKESKSGKSPSRKGRSKSPSKKDGSHSPTRSPTRSKSRNEKRSKKKEEPAEEPPPGKSETDHDAGTEGSGPDPDADEKQQEAAGGGGGGGGGEPSASKEEAPQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC14</accession>
    <name>A0A1D2MC14_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001961">
        <property type="protein sequence ID" value="ODM90451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC14"/>
    <dbReference type="OrthoDB" id="8293295at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="309" mass="35218" checksum="C65262004B1101C6" modified="2016-11-30" version="1">MDLIGLTLVTTGVLFVAALLFRFFFSTQKFRNGSVTQHQVTLEDASVPFSANEISNQILSFHENLREDEDQLATIQKVQTLLISARNEIQDDFDTRNSLIIGVDATPHTQAGYCVNPFDKSIRFYVLKRADFPWKFDNEKDPAEFEMKNLMFALTIWKNQIIWLKQLSIYTDNFAGVFGSQYGVRAMNYLQHFVDCEGVTVVNRKRMALNKYQSLPSFAKYIQPADDLSRWKIDAALEFLTKMYDIDMESVQGTHQKVALSSTSKPRYKLTPFSKRICDSANRVIAKGLRCGNPVCSTAAMSLVLKNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCT0</accession>
    <name>A0A1D2MCT0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001794">
        <property type="protein sequence ID" value="ODM90785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCT0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903807" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="9829" checksum="2C4A8D7652BA395C" modified="2016-11-30" version="1">MLTKYFISVALLCMLLCASIDAEIFEDTIAIEEGAKAEDVTPFKSIFFPVGTNDCRVPDLFAVTVNGPVVALSMAVAGAVVKSHTRFQPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MD17</accession>
    <name>A0A1D2MD17_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001793">
        <property type="protein sequence ID" value="ODM90791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MD17"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903835" evidence="2">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="11166" checksum="8D18E5D2C778F029" modified="2016-11-30" version="1">MKRLIVTFVFTTTLILIWTSSAKAQFVSTAERQQFATTQTANARTAQGVSPRSSTTLPPPNQTIQCWRCSSPCSRSYCCADTNPQCGILDERRCQCFPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDB7</accession>
    <name>A0A1D2MDB7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15674</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001704">
        <property type="protein sequence ID" value="ODM91008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDB7"/>
    <dbReference type="STRING" id="48709.A0A1D2MDB7"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048598">
        <property type="term" value="P:embryonic morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="370" mass="42593" checksum="099317B2428EFD58" modified="2016-11-30" version="1" fragment="single">NGKPLTINEEKKKRRPAELPDHITVHSVAGSETYQCNICGNRYRTKANFKNHLSCKTGIKLFNCDKCESSFNSLSHLKYHLRGHLGLRPFPLSFDRHVNQVHGNIRRYKCEHCPQEFYSKYSVKVHLVSHTGERPFVCQECNQRFKYASALRKHSFSHDTHRFMCYKCDMAFPTLIDFEEHLRHHNITLRPYRFTRPDNLRRHEKMCEQAVNVDGDVINIGRQQIEHDVDVGTEQLYQPVERVKVPAENEVAGAYKVPEIAEDLNPTRLESSTISANAGEYFYQCRMCSQCFNRLELLQSHLVSTHELSPDVSKILQNEGVNDLEPPSPQQSQLMKNTSTQTTGVFVLLVPIPVFIPVPTTFVSTTYATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDP5</accession>
    <name>A0A1D2MDP5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IgLON family member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001703">
        <property type="protein sequence ID" value="ODM91011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDP5"/>
    <dbReference type="STRING" id="48709.A0A1D2MDP5"/>
    <dbReference type="OMA" id="EEYHIER"/>
    <dbReference type="OrthoDB" id="10031887at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF45">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 12, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="112" mass="12746" checksum="991E8610083D2C91" modified="2016-11-30" version="1">MGLIVSAVYSQISWIRRRDWHILTTGKTTYTNDERFNVLHVDGTEDWTLQIKFVQKRDAGIFECQVSTGTGIISYFVNMFVAVPEAFILGNGEYHVEEGSNINLVCVIEKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDP7</accession>
    <name>A0A1D2MDP7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15640</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001692">
        <property type="protein sequence ID" value="ODM91042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDP7"/>
    <dbReference type="STRING" id="48709.A0A1D2MDP7"/>
    <dbReference type="OMA" id="CRIENHI"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="341" mass="39187" checksum="8EE718A38A4C2FAF" modified="2016-11-30" version="1">MEGQLSTLTLRHPALPKVIKGNPNGNELQVSTICSAGFASSSGLKKHTLSHSNERKHKCQRCDKLFKTKVYLNNHIKGVHIKSQRYPCTFCGKTFGYQKTLSAHKKIHLTEPPHKCNICGKAYRERRQLEGHVNKHNNKKDFKCSQCHMKFFYNKALLYHNGTVNSPPKYNCPFCDRGFASICRIENHIRGHIQERPFACPICQSSYGSNDSLQKHLQLHRGSTRKIYKCQVCFKTFRSSKGLSTHIRLHTGELPYSCKYCGESFKQKDYLKQHVIRRHGTQPSDHSNLECCLFCKKVYLLTTVYSRETIFCSVCGSEFGLNGDLKKHLIKHTNEIQMISM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDT2</accession>
    <name>A0A1D2MDT2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein nubbin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15546</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001657">
        <property type="protein sequence ID" value="ODM91135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDT2"/>
    <dbReference type="STRING" id="48709.A0A1D2MDT2"/>
    <dbReference type="OrthoDB" id="6358449at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013847">
        <property type="entry name" value="POU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050255">
        <property type="entry name" value="POU_domain_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636">
        <property type="entry name" value="POU DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636:SF89">
        <property type="entry name" value="POU DOMAIN PROTEIN 2, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00028">
        <property type="entry name" value="POUDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="28"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="87" mass="9737" checksum="B7ABABF15F446B2F" modified="2016-11-30" version="1">MLWLDAANNALNNPSAKHNATDVPIRKQRKKRTIIGKTAVAALDEAFRLDSKPTNQEMGALADKLSLEKDVVRVWFGNREHELEPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF64</accession>
    <name>A0A1D2MF64_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001474">
        <property type="protein sequence ID" value="ODM91619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF64"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="45" mass="4995" checksum="715EEB60B480B033" modified="2016-11-30" version="1">MALIWCIPKKSLIGGYYDRSGLLIGDGNYRYIDESDGTTIFSTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFG6</accession>
    <name>A0A1D2MFG6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein LLP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the learning-associated protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001449">
        <property type="protein sequence ID" value="ODM91703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFG6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFG6"/>
    <dbReference type="OMA" id="FSIRMAK"/>
    <dbReference type="OrthoDB" id="6257894at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001099">
        <property type="term" value="F:basal RNA polymerase II transcription machinery binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097484">
        <property type="term" value="P:dendrite extension"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018784">
        <property type="entry name" value="LLPH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34253">
        <property type="entry name" value="PROTEIN LLP HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34253:SF1">
        <property type="entry name" value="PROTEIN LLP HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10169">
        <property type="entry name" value="LLPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="18574" checksum="C0820E54BDDA0125" modified="2016-11-30" version="1">MAKSLRSKWKRRMRAEKRVRYGEKELDRLKTMLTNAGDYQMVGEDSTQNTIPPPSTSAREPLAVSIVKRNKREVSRKSRKDEYQDDQFEMTPEDEALEEDEAMSVDKAERVYSKRTMKDQFGNYPVWMNKRKIMAQRKVNKRIGKRAKSAAAGKRVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFH8</accession>
    <name>A0A1D2MFH8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DDB1-and CUL4-associated factor 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_14936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001433">
        <property type="protein sequence ID" value="ODM91748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFH8"/>
    <dbReference type="OMA" id="AHFFHNS"/>
    <dbReference type="OrthoDB" id="6354267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20913">
        <property type="entry name" value="DCAF15-CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20917">
        <property type="entry name" value="DCAF15-NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038914">
        <property type="entry name" value="DCAF15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047319">
        <property type="entry name" value="DCAF15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032734">
        <property type="entry name" value="DCAF15_WD40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28541">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28541:SF1">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14939">
        <property type="entry name" value="DCAF15_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDB1- and CUL4-associated factor 15 WD40 repeat-containing" evidence="2">
        <location>
            <begin position="66"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="942" mass="105613" checksum="E08D511FA963FEBE" modified="2016-11-30" version="1">MFQSLGSPSDAGSGGLSVKGGVNCKPWDLRKGSFGNKGSILTNLFRREVYGSSLHKLANPFGEYGTPTRLRMPIEEVIPPSALEAGNIFMGFTNCGRYILSYTCRPSENFGSVFDSDGTYMYTLHIWLFKPYSKVRKVSQVCLFDNNGVYDNNLLIDICQWEMDDSHLLITGHSANPDTECHHTFYTTITTIPDARNCPNCVYIQDDELDDESRTRTNCILHGLTIHMKYDHVPPFPKMNADVQLRFKDAVLLNTGNVIHVVSFRLLRPCPPKMETAVVPAAASAIVSTTRFPLRCDIWLKIPNANLLALASVKVNAQGYEGGKTVEENIISLNALDSLSRFFPASTSTKPQNQNLQDALSRPHRRLSQSSTDSEFSLFSPKSFTGCDFGPMSPPFLNKPRSPRRNESSSSGQNQNMNISPSKLMLPPQERKFFKRRLSSQNLTSGINEVSTETLQSPTKSIEEVAQSDSTQSQQNQSAFDVFEMRLEDTAVERHLSSFKTFRKRRLADKKYEFNDADHSAENIIPLKMTRRKSKYSLQGNAMNFSNPRSPRNENVAAGGNESPRGSYSELSHPKSPRAHYIMSPVMSPNYMNDSSVSDVLRPLNNNSKVKVSALSPNSNLNSFDASEVSKVKEEDLDKDVSSHALLQGPKKVDIVDIPSHPHAKPTISVHVNCVAKVLRSYIQKEDDNMSVITDIEDEQYQGYPFPVALPLEVHGAGYQQLQMISNSKADKFQVPVVQVLQRTLDIEMLCNEVANLICLASDKHYCSCIDFDLAFAEANPDRGTVTSIVVMLVQATSIKQRNRGEKVNHLAYYNGRMKYEAFFCCEWVPNREHCRILYKSNLQELETVPDPWHPTENMESIIKCHLSTLLPTKKTLSNALAVHDWQSLDELVDASGIVTLFKDEGSTLKTERRLNDFNSVMFETNVDLASTTTDSDDEWGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MG74</accession>
    <name>A0A1D2MG74_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001357">
        <property type="protein sequence ID" value="ODM92006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MG74"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="135" mass="16264" checksum="30C8D9C60E2EB3E5" modified="2016-11-30" version="1">MECVYEYREMHMEKFFEERRQFEIEHQTDMIKYFKRAYQRDVAMILLILDKLEWKQTVSGGNLTTMEQQAMVEGQLMLMQVMHAYQSEIAYREEELKELGVRMSRPAGMQPNLSKAILYFLRSNRFPINSSMFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGA2</accession>
    <name>A0A1D2MGA2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Casein kinase I HRR25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001358">
        <property type="protein sequence ID" value="ODM92003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGA2"/>
    <dbReference type="STRING" id="48709.A0A1D2MGA2"/>
    <dbReference type="OMA" id="NVECTRT"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903976" evidence="1">
        <location>
            <begin position="22"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="20271" checksum="FA6B0C46D8F81E83" modified="2016-11-30" version="1">MFFLLQNLMLLFTGLPDRFRARYFVPRSFSERHLPREKSKRFIGTAKYSSLNTHLRFRQSRRDDLESLGYIFLRLLGKILPWSLESTDGEIFMSKKNTSSGQLCKDLPKPFEEYLEYCKNLEFAEDPDYPRLRKMFKDLYDELGYVEDSVFDWMAHVEVENKESVFYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGQ1</accession>
    <name>A0A1D2MGQ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001301">
        <property type="protein sequence ID" value="ODM92186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGQ1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="40" mass="4399" checksum="5E9324CB4339C38B" modified="2016-11-30" version="1">MLCSLSTSGKENREKSDVYTVSSAHQPVSVLIPNQINYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH47</accession>
    <name>A0A1D2MH47_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 26B-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001300">
        <property type="protein sequence ID" value="ODM92194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH47"/>
    <dbReference type="STRING" id="48709.A0A1D2MH47"/>
    <dbReference type="OMA" id="GQNTFNE"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000015">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="316"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="45211" checksum="705CC1AE400D9C9E" modified="2016-11-30" version="1">MNFFGFGPSADLDIVLDDQLSRKTALLKTEDGKKLSHLLYLDGEDLSGKLHLHLKKPGSRLEHLGIKIEVFGQIEMYYDRGNFHTFLQLSRELARPGELLQHTTYNFSFPKVEKPYESYTGANVKLRYFLRATVVRRLSTDIVKEKEFVVHTLSSYPPHETINSSIKMEVGIEDSLHIEFEYNKSKYHLRDVIVGKIYFLLVRVKIRHMELGIIKRETTGAGQNTFNENETIVKYEIMDGSPVKGESIPIRLFLGAYDELTTTMKDVNKRFSVRYYLNLVLVDEEERRYFKQQEIILWRKGEREKRQPFQAQLQQQYKQMQNPNVRLETPVGERVSPTNQEGFDTIPGIEPEDENEENLNPLLEENDEKEKDEVEASPPHLQKLRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHI2</accession>
    <name>A0A1D2MHI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001248">
        <property type="protein sequence ID" value="ODM92381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHI2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="118" mass="13921" checksum="75933529A019930B" modified="2016-11-30" version="1">MGSKRLEVYTVLLATAWFEKGTRCGGGIFLVLKPNETFLYDYMETYWVVDEDKFQKQMVPNVPLAVPSESNRILKNIMYSTIKKVPCTDWHFYLCKKMFKPQFQSVRLQRTTKSHNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHM0</accession>
    <name>A0A1D2MHM0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_14174</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01001212">
        <property type="protein sequence ID" value="ODM92508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHM0"/>
    <dbReference type="STRING" id="48709.A0A1D2MHM0"/>
    <dbReference type="OMA" id="DITRECG"/>
    <dbReference type="OrthoDB" id="302728at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="187"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="676"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="680"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="708"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM92508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="732" mass="83176" checksum="F2DAF6EA2FB800F3" modified="2016-11-30" version="1">MSRFRGQRRLTPAERSNLDSTRVANLNYVLRRYGGLDVYIPRIIGTDPTDRPGPAAVVPAMGGTETSTSQSNFSLAQQARPPPGPYGNYTPLFKGRFVLGPEKGLFFLSLFLMLGIMLLIITEKESIETLCGGPMVFVTGLVLCACSTFTFFHLGITDPGVVPKNYSLQELLVETTEFRSRHPLERFHRYCRKCRAYRPPRTFHCSRCQVCIRQQDLHLFSGGICVGERNRRVYFFTVIFQTLLGVYLVATNLVIYVTVRQQAAKHFSFETIKTVESLVGCLSGFMILFMPQSGILMFIYRIYLMSVGRTAREEYRKFRYFDAHDCVVDRRTPCMNIFHFFFQTPLPSVFRRRANRIDPESFNPIAPTEWQLDQIRRTAERDPNRRHVDRFALNRRQFENIDLSLISLSHVADDARGRRSTSSVPLFEQEMYHPTQRIKIPRKSKPSSIIKQQISAYEDSRYRPRATISRHKRRKLALTLSDGNFPRTNDDSFQEMIQLARATQLRRIIQMILMRDRPGLIEMSRRVNIAALVGMNRFDPDNLQLLELNNGLPMIAPRRREADQGVNQPRLGAGVLGIPQMVAAGLLPTARDLADSVESMVGRGRIRRLPPVGRQRYIPITVVDPPLARRAVNEVDFRGFIPQRTPLSQVRTGVGGIANTTTTPLPEVVATNNVTENLHSSPSQPPVTSSVPQIDSFPARGHEEDRNNNSATLPPQFRNFVNGQSSTADTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHP1</accession>
    <name>A0A1D2MHP1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001208">
        <property type="protein sequence ID" value="ODM92528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHP1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="334" mass="37619" checksum="BF3C6B49F6D65711" modified="2016-11-30" version="1">MIVTVIFHQLWYINSILLFTMKHHFNSLLTLVYAILLLKSTTDGLMCYGCLLLTPFFDIKNNPAKISKGDSSCTYHTNTTCVPPETKCFIHVVKSGRDIKITKGCTEDTSDGCLQSNTDTEQKCFCKTRLCNTDIEAIGGKSIVGFLLTFIVFNLLYRDIQMLSCCLGSRHLQTEDEDNLTNDCTNTARTCSSVDCADNKCQPSTSTNNSHPETECGKVKCDVTGSNGFCRIYYYEVRKCDPDCVNITSPDANKKNANTGEWWVRQECYEDTDRELKESCNFKHIIVHLDVMTRVTVEKDCYCKEDDCNADIGKACRTVLVQSLKLIDLAICTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI83</accession>
    <name>A0A1D2MI83_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lysozyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001176">
        <property type="protein sequence ID" value="ODM92683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI83"/>
    <dbReference type="STRING" id="48709.A0A1D2MI83"/>
    <dbReference type="OrthoDB" id="6338733at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031640">
        <property type="term" value="P:killing of cells of another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00737">
        <property type="entry name" value="lyz_endolysin_autolysin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04110">
        <property type="entry name" value="ENDOLYSIN_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051018">
        <property type="entry name" value="Bacteriophage_GH24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033907">
        <property type="entry name" value="Endolysin_autolysin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034690">
        <property type="entry name" value="Endolysin_T4_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023347">
        <property type="entry name" value="Lysozyme_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38107">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38107:SF3">
        <property type="entry name" value="LYSOZYME RRRD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="3" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM92683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="406" mass="45078" checksum="8DD38702A7093E26" modified="2016-11-30" version="1" fragment="single">VKPQDKMHFKLNNFCETQSVLVRRNRVYKSKTLEVACWLFSLLPLKTIMNLYFCIILVASTAVSAVKYTGPTNQAGRNLIKEFEGFYANFYNDPVGIRTIGYGHACHVWSCSNPLNGKYRVPLTRSTAEQLLIEDLGAPGRYEGCVNNAVTYNNLNANQFSALTSFVFNMGCGNFRSSTLRRKLNRGDISGAANEFRKWVNAGGRRLSGLVRRRAAERALFSAASLLVTGCTARYTGSTNKAAVNLIKEFANFTADFNLDKTASKPTWTIGYGHTCPCRGSHNPNCIGNACTVPLKGTITLPLTNSSADELLQDDLKEHEVCVRDNVLYKSLTSNQFSALVSFVHSFGCGQFQKSDLRAKINKGNISGAAKEFMKWAYSGTPPQLFEHLKDWRIAERKLFCLGSQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIP9</accession>
    <name>A0A1D2MIP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001129">
        <property type="protein sequence ID" value="ODM92876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIP9"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13717" checksum="C5FC0FD2F9BFB526" modified="2016-11-30" version="1" fragment="single">NTQKGSDRVRDFLAKAFQDEAVLVMYLIGRKYRPLHAFTTLQSYAEMRFDKYPELFPTTLPPKEYLIYDNQPIFGILKGRDSKGRRIAFFQIGGWDTSKCSMMTWPYLHCQFLSESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIQ3</accession>
    <name>A0A1D2MIQ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome b5 reductase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_13826</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001133">
        <property type="protein sequence ID" value="ODM92859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIQ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MIQ3"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008028">
        <property type="term" value="F:monocarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF306">
        <property type="entry name" value="RE01051P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="628"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="658"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="691"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="4">
        <location>
            <begin position="759"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="974"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1219" mass="134156" checksum="30246C296BFA7C9D" modified="2016-11-30" version="1" fragment="single">MSEAPLPISSCRSVGDKPTREAATASKQSSRRIVYKCKTIEAYDGSQGWCMVCLVFLTNFLVLGFFKSLGMLTKILNKEFDVTMHVYILMCITYSLNCAAGPLACYLTRRFSARSIALVGTSMVSFGLILSWFAESLTFLYFSVGVLTGVGSGLTYPSGVILVGNYFVGTKRAGLANALIVSGSPVGGMIMPGVISALSQIYSSRGAFIIVGGLMLHSIICVRAYTPPPKGIPRDNMDSQDDETLDNADKPEECVKEVSDGSLPLIEEIKLEETSLDKGKRDDGPNSELPEISHSTGILKIYERDNDDVECNKPLSGLSIDVRYRPNASHGASPLLPDLVGSGTKSVFLCGTGQKINAQGSPIVPSELKAKESNVSLRPFGNICNKCRDKSRLVASDGGLECYRKGEGESTPYNMLQSAFQGKEVVARMLEIDRNLNVRRFPVPACTASAGSRPYILSLDHSCIILCSETDLLKKGDHKMEDSFNNNRRTVSHFRIGSGDDASASNIPETSENGSCIQRIKRWILKSPLRNSTYVFLLLSNNATAISTNNIHLMVSQLVEETDDSYTKSSLLYLLISVADLTGRLLGAFLADRNVISPSIIYAIGLIFAGISSSFLAALSTYNQLCGVALAFGLFSGCHIGIYGFLLTDIVGLENIHLGYGISMFLNGTLQCIAILVSGRAVSLNKGGFTWLAPLLGAILTCGGLIWTCSLLICQRKDAPTRRRKDSEYCMNTNNAKEIPPKNEDYRVSLIKNSSASKFNAISLEELAKHNDVPNKNAWICIKGIVYDVSAYASKHPGGIDKIIKYAGKDATDVFNMVHAYVNADAILKSAQVGILKGHHHEAQKKPLNTKLKEKEWCCFGGSYKKPTTNFKQDSIVGTYTVEFLHSSHENDWTVGVKDQRFLQVFKKIDISQAWYSSYELPEPLCNDHVSVQFKNNYEHVEITIRKPVPTTMWARQSHGLKDCGTFVPMDRSQAQYPGFILSKRCLTHNIILFAIQICPSARIGVPIGHHVSLHIGGTSRPFTPVLPTIVDITSEERPKIDPHVLYFIIKIYPNGACSKVLDQVEIDDGREIPSLQIGTPQGSFDAEFLNDFNLLLLIAGGTGITPMIKIICHFWNMSERMTGRQVVFMYFCETEHDLIWKSQFYDMHEAAPWFHYFPVLTKPAPGWEGLKGRINDELVKNCIAELRSESKSLKKACVCGPPGFNSNTTDRLTSHNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJ89</accession>
    <name>A0A1D2MJ89_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PDZ domain-containing protein GIPC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_13633</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GIPC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001091">
        <property type="protein sequence ID" value="ODM93049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJ89"/>
    <dbReference type="STRING" id="48709.A0A1D2MJ89"/>
    <dbReference type="OMA" id="ETATNCE"/>
    <dbReference type="OrthoDB" id="6509831at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21180">
        <property type="entry name" value="GH2_GIPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06707">
        <property type="entry name" value="PDZ_GIPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000097">
        <property type="entry name" value="PDZ domain-containing protein GIPC1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055349">
        <property type="entry name" value="GH2_GIPC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056814">
        <property type="entry name" value="GIPC1-3_GH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017379">
        <property type="entry name" value="GIPC1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12259:SF1">
        <property type="entry name" value="GH21964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12259">
        <property type="entry name" value="RGS-GAIP INTERACTING PROTEIN GIPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25083">
        <property type="entry name" value="GIPC1_GH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25082">
        <property type="entry name" value="GIPC1_GH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="138"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM93049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="351" mass="38591" checksum="7649F5AB0150AB9B" modified="2016-11-30" version="1">MPLFDKKRLTNGGGSAPVPPPRNGNAAPYNNNQYKNGNQGSGYQFETVENGLVQRSTVSKPKLVFHCQQAQGSPTGLISGFSNVKELYQKIADCYDFPIDDILFCTLNTHRIDMENLLSAQLCLDDFIFVHRKGTKKEVELTKSEDALGLTITDNGNGYAFIKRIRDGSVIDKCEAIQIGDHIERIDNENLVGWRHVEVAKYLKSIPVGKTFVIRLVEPLKAGFMNIGPKSDPKGKGNKGKSYGSGKETLRFRSNGPAQIEQAPDDLAKTAIESINRLLENFMGINDNDLATQIFEMAVSKSNTMELAEAVDNSELESFGFTDDFLIDVWGIVTDAKSGRLGGRGGSDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKN7</accession>
    <name>A0A1D2MKN7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000946">
        <property type="protein sequence ID" value="ODM93599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKN7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904193" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="568" mass="66524" checksum="283B2E35DBA0D434" modified="2016-11-30" version="1">MCTHLCISMFMFCCLQRNSLFALSKSSLFICSFWVITTEKVKMGDGGNAFLKRHPLEIFPTEVWGIIFEKLKDPKDLASCSRASLTWNDILVEGKTTFLFPEVMSVIAAKKNISPFNFVANHPKCDIRNLRLVCLTWRAAIDNYVQCHPCHFQLEEPSPINDVNEDHHRFKVKSAVIFSTPESLDSFQRGLISYRGGNPFLSRHVILSDTNPDNIHNTNRMWAGFKNLLFLWGPQILYFEVIIHSEHYFFQIYQNIQESLCMMPNLRVLKLKPIEAMVRRELEVDWMRQLTETSPIPRLEHLEVFCARLIPTPMMNEALKNFPNIRCLLMEKEFGIRHEYYDYDAENLSLPKLRELVIPLVTANDLRTFERVTWPLETLKFVIYCKEAQTFPPNDVDEWLDITNILLCVSYTNPFGSTLKNLTLKLDGQNPWKAPMVRCSNVELNILHLQKLYIQMKSVQLENIEFVRNFNELKHLSIVMDSYQVGSCSTPESFFQSQREGEGNAELKFFSFMEHMNMYDSNVWELLPTLESLVFKLRPNVRLNTEFIKFRFKREEYNAKQSCSLFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLR3</accession>
    <name>A0A1D2MLR3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative cytochrome c oxidase subunit 7A, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12749</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase VIIa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000887">
        <property type="protein sequence ID" value="ODM93933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLR3"/>
    <dbReference type="STRING" id="48709.A0A1D2MLR3"/>
    <dbReference type="OrthoDB" id="5966508at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097250">
        <property type="term" value="P:mitochondrial respirasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002082">
        <property type="term" value="P:regulation of oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.91.10:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit 7A1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.91.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039297">
        <property type="entry name" value="COX7a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036539">
        <property type="entry name" value="Cyt_c_oxidase_su7a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003177">
        <property type="entry name" value="Cytc_oxidase_su7a_met"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10510">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10510:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02238">
        <property type="entry name" value="COX7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81419">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="97" mass="10846" checksum="63C9DC06258D90F5" modified="2016-11-30" version="1">MNVTRMAAPCMKLSKSLVVPHSGVMARFASVTKGQVHPGYEKIKEKYKHFQIEDGVPIHLKGGAFDRFLYYTTLAGCGVGLVMCFEYYYSAAFPKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLX1</accession>
    <name>A0A1D2MLX1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Neurexin-1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_12743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000887">
        <property type="protein sequence ID" value="ODM93938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLX1"/>
    <dbReference type="STRING" id="48709.A0A1D2MLX1"/>
    <dbReference type="OrthoDB" id="6275838at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050372">
        <property type="entry name" value="Neurexin-related_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036:SF89">
        <property type="entry name" value="NEUREXIN 1, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036">
        <property type="entry name" value="PIKACHURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Laminin G" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="126" mass="13501" checksum="557420B0EAAE2491" modified="2016-11-30" version="1">MQTNSIHTRVQATSSRINDGEWHTIKLIRNGRSGTISVDDFNTDFNLKSESRILVLGTIYLGNVPSSVADENVWNVGLGNGFVGCLKNVVIEHTLVDLVRLANSQDIVGSAFCQVVALGSASATLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MM29</accession>
    <name>A0A1D2MM29_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000891">
        <property type="protein sequence ID" value="ODM93911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MM29"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904238" evidence="1">
        <location>
            <begin position="23"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="10094" checksum="D7F84C6894BF513C" modified="2016-11-30" version="1">MGSSIFFCCICLLFSQVVLIQGIPVASFPQEDNKVDSAVDPLFLLSISGESGEGAFNLRFPRAAIVNPNNAPQFFRLDGGHHDDHHHDHHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMB4</accession>
    <name>A0A1D2MMB4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein-like, C3H1 type-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_12512</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000849">
        <property type="protein sequence ID" value="ODM94169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMB4"/>
    <dbReference type="STRING" id="48709.A0A1D2MMB4"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000001">
        <property type="entry name" value="zinc finger CCCH domain-containing protein 15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000002">
        <property type="entry name" value="Zinc finger protein 36, C3H1 type-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF174">
        <property type="entry name" value="MRNA DECAY ACTIVATOR PROTEIN ZFP36L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM94169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="35773" checksum="913C867E5D46DE04" modified="2016-11-30" version="1">MPCNNTAMMLPLAMENSNHHGGGGGGGMPLIQPNNKLGITKAQQQQLAQLQQQQPQPGSNQSSRYKTELCRPFEEFNVCKYGDKCQFAHGQGELRKMPRHPKYKTELCRTFHTLGLCPYGHRCHFIHNSDEINMAPNGGNNRENNNAANNNNSNSSGNGSSSGSAPSTPTSIIGQGLPTTKDLVTHRSSSMSSSSSTASSSSGVGSGGSSPVYHNNHHHIPHNLPQLPPFFPPNHQHHNSTTDLLAAANGLAFGAMNPFGAAAHAAAVQAANSVLPPLSPSQSPSFCSGGSSVPSLSSSPPLSATSNSSLSASSHFYAPVNFYMESNHRLPVFWNLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMD9</accession>
    <name>A0A1D2MMD9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000839">
        <property type="protein sequence ID" value="ODM94220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMD9"/>
    <dbReference type="OrthoDB" id="8178576at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39945">
        <property type="entry name" value="FI14129P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39945:SF1">
        <property type="entry name" value="FI14129P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="159" mass="17797" checksum="1580020D80BC5C39" modified="2016-11-30" version="1">MSCPHCDNNFSLSESNNQELLVSEESEYAIGAVLISSDFYPLCLQMEVRVVTVAVMAIVTMTTFLALVQEAEARPSRSTVAEGWPEYMSLFHRGGDPHRRAVNECDNSSAVREICQRCAKATKSKWAYPLCCEAEEDTRRFCVNFLNFGISPNDVINQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMM3</accession>
    <name>A0A1D2MMM3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12559</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000857">
        <property type="protein sequence ID" value="ODM94121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMM3"/>
    <dbReference type="STRING" id="48709.A0A1D2MMM3"/>
    <dbReference type="OrthoDB" id="907479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08554">
        <property type="entry name" value="Cyt_b561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043205">
        <property type="entry name" value="CYB561/CYBRD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10106">
        <property type="entry name" value="CYTOCHROME B561-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10106:SF0">
        <property type="entry name" value="LD36721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="320"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM94121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="642" mass="74152" checksum="EE85D2E87C78220E" modified="2016-11-30" version="1">MKHAWLFEEKKLSREVFWTSFSTRLSNGKRENADKEFENHFSWQIVPCVYYHTHQKGPIFVTPLIMAGGSRKLDYQKLLNESLKATRASVSAQKKEYGENYKSKYSHTVEAVRKRSAPVTSVRKSRQSRKSIGTDRMSPYSRYSLLKRQPNRKKSVVAASTMKSNEFGGFFMEADKERTARQKLRVERNKIRFSLGTNLEPKSEPNPRRPSIPATDDDSFTSMQLHTRDWHYKPNVPRRSITFRDGSIDIKIDMGDMLTQDQKKSSDDWDDDEDSSSLNKGNELATEDSIISIRHGKLYRNETLEEYTKSWQHFIQFLSFELVVALTLIVLTTVFIFVFNYGFTTSGSMDRKIMTHDRSRVLLNAHMLIMIVPNSVILGISVLTYRTFRTISRTHMKWLHGSLALIATISFSTGLYYCIIYHRVSGSPDLNSLHNILGLFCCFLQILQMATGFVYILPCCSWDIRVSLTSFHKTLGSTLLMAHGAAILTGCVNMTNKFYDTKNFPQYYPYPLWVPQKKSSVMSLIGIMTIFFITNTLYIQGNFHFRRRIKPGPETAQPCDPDDDAICKVNIRRKSMALSQESKRPGTGEDVQIGSRQSFNAKRLMLPDYGYNNQERTIPMMLNGLQQHRSNFNDDYFFWTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN86</accession>
    <name>A0A1D2MN86_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription elongation factor SPT5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">DRB sensitivity-inducing factor large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Transcription elongation factor spt5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_12199</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000801">
        <property type="protein sequence ID" value="ODM94486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MN86"/>
    <dbReference type="OMA" id="SMKSINA"/>
    <dbReference type="OrthoDB" id="28901at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06081">
        <property type="entry name" value="KOW_Spt5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06082">
        <property type="entry name" value="KOW_Spt5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06083">
        <property type="entry name" value="KOW_Spt5_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06084">
        <property type="entry name" value="KOW_Spt5_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06085">
        <property type="entry name" value="KOW_Spt5_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09888">
        <property type="entry name" value="NGN_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000013">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000016">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.940:FF:000005">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="entry name" value="NusG, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041973">
        <property type="entry name" value="KOW_Spt5_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041975">
        <property type="entry name" value="KOW_Spt5_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041976">
        <property type="entry name" value="KOW_Spt5_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041977">
        <property type="entry name" value="KOW_Spt5_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041978">
        <property type="entry name" value="KOW_Spt5_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041980">
        <property type="entry name" value="KOW_Spt5_6_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057934">
        <property type="entry name" value="KOW_Spt5_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057936">
        <property type="entry name" value="KOWx_Spt5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039385">
        <property type="entry name" value="NGN_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055272">
        <property type="entry name" value="POPDC1-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039659">
        <property type="entry name" value="SPT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024945">
        <property type="entry name" value="Spt5_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022581">
        <property type="entry name" value="Spt5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125">
        <property type="entry name" value="SUPPRESSOR OF TY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125:SF7">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12815">
        <property type="entry name" value="CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23042">
        <property type="entry name" value="KOW1_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23284">
        <property type="entry name" value="KOW2_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23291">
        <property type="entry name" value="KOW4_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23290">
        <property type="entry name" value="KOW5_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23288">
        <property type="entry name" value="KOW6_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23287">
        <property type="entry name" value="KOW7_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23037">
        <property type="entry name" value="KOWx_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04831">
        <property type="entry name" value="POPDC1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11942">
        <property type="entry name" value="Spt5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01104">
        <property type="entry name" value="CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="18" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1187"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1210"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="domain" description="NusG-like N-terminal" evidence="15">
        <location>
            <begin position="182"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="491"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="613"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="741"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Spt5 C-terminal" evidence="17">
        <location>
            <begin position="804"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="1082"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="37"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="325"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="670"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="807"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1420"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="690"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="706"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="727"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="807"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="843"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="901"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="916"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1420"/>
            <end position="1446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM01104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM94486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1599" mass="177369" checksum="286FD554D64F1081" modified="2016-11-30" version="1">MALVCASSTDPRKFISNLLISDRVRSRVIFSSFSAVSNTSGTPRFVSRSYDEEEEEEEEEEEEDDEEDDEEYARKRAKKRKSGVGGFILEEAEVDDEVEEEDEWEEGAEQYIHGNERDEHGPTAREIEGSLRRHSIWERRRSWRSTCVRSTQTRRRRSVTFGDGEDMSDEITQQTFLPGIKDPSLWMVKCRLGEEKYTVLQLMRKAIAYANNNEPLQIKSVIAPEGIKGYVYIEAFKQTHVKNAIEGISNLKMGLYKQQMVPITEMTDVLRVTKEQTGLKPKQWVRLKRGVYKDDLAQVDYVDLAQNQVHLKLLPRIDYTRMRGAMRSDSDSPNKKGFQKNQQANQRKRRPAAKPFNADEIRKIGGEITSDGDFLLFESNRYSHKGFLYKTFQLNAILAEGVTPSLAELEKFGEVPVEGVLESGASVSAQGSKSEVTHNFATGDNVEVCDGELQHLQGKITAIDGNKITVLPKHEDLKDPLDFQAAELKKFFAIGDHVRVIGGKYEGDTGLIVRVDTHCVFLFSDLTMHELKVLPKDLQLCADMASGVDSMGNFQWGDLVQIDPQNVGVIVRLEKELFHVLTQMGKVVEKKPQAIHKKRESKFVVGIDSRGNSIQKRDIVNVVDGVHVPDRQGEIRHIYKNYAFLYSRMCLENGGIFNWLGRLQPEDRRRAKPGAGYMSPRLSSPMHPSSGGGGGGGQPGGPPNAAGTSTPQNILSGGRSPLGPGRTNVTPGMPTSQRRNRDLIGQTIKITQGHYKGSIGIVKDATDTTARVELHSSCQTISVDCNRIQVIGGAGGKTGNVTTYSRTPGYSAGGSSATPMYRVGDGGRTPMHDGSRTPHYGAGNQTPMQDGSRTPAWDPTVTNTPARDDSEYYDTSYNPATPGYSHTPYTPQTPGGYAASEHSSNYSPYNASPANEARERGSERGSERDRGSHRDDPSSPGGYGMLHSVPSPGGYAPSPLNYNSPMTPSGAGRGNASADVYGHPQTPGAGLDPYSSLGGPSSVASATSSVLHGSMASHSSHAYASEWQTTGIEVMIKETHPEPGLRRQNGVIRNVLVGTCAVFLVQEERTVNVQSDQLIPLIPKTGDRVKVIAGELREAFGYLKSVDGSDGVVDIHGDIKFFPLSFLARLETATQASAHSSDILTNYRCVLLNYPVNSTSLLSYYSLWFINSNPLYPPNHFTPIHHLIYQLSQLGLLIFLTVAHVSKWSVLFITAYVVLSLVWGVLILKSIDMMVWNAVHLLILVVQFIRCCCGHSEHSRKHMHSNVKVSSSGNLAKHSEIDNVYSRLFAPVRVTYKQFMKVVACKRGFKNLGCGENYAVEKRTRVDSLGLLVAGWKPLHVILPFQFVDSPEYFGVATDELFQVTITALEDSKLLVWHRDKLRLTIMNDEFLRVIFDHIIGRDVVRKLIQVSDTIMTTTTTFSSSTSPASTTISPSSPSNGNSALPPSIPQQPIMVIRKDKYAYQPTYLTSLSESGVVRSTRTVSRTRWRSTRRRSPTTVYNKFLNSRLLVEEHDFDVIPVISLGAHVYFSHVAAVRAHVLPGRAAARAPARAVLLSLHRQPHHRHYALLLGWRAVWGRVLGHLRLCYLLARYRDARDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNP1</accession>
    <name>A0A1D2MNP1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Signal transducer and activator of transcription 5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_12029</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transcription factor STAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000774">
        <property type="protein sequence ID" value="ODM94657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNP1"/>
    <dbReference type="STRING" id="48709.A0A1D2MNP1"/>
    <dbReference type="OrthoDB" id="7993183at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.630">
        <property type="entry name" value="STAT transcription factor, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001217">
        <property type="entry name" value="STAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048988">
        <property type="entry name" value="STAT_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012345">
        <property type="entry name" value="STAT_TF_DNA-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11801">
        <property type="entry name" value="SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21354">
        <property type="entry name" value="STAT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SH2" evidence="13">
        <location>
            <begin position="211"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM94657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="406" mass="46404" checksum="6AC8FA963F52CF41" modified="2016-11-30" version="1" fragment="single">KYSMVTPFGLEVTPEMSSVNTGLKLVCMSISKHRQHFNAQLRLKIMDVVRKNKGKEKLSIVANEKYCFLFVAELPIRDKIVKTWTTSFPLIVITHGCDSMNGWAAATWDNAFPAPNREGFEVRPTAYWCQLSEMLGSVFRMWVGAESSLKPSHLECIANKLKLCTGDAFPQISWKEMVKGENTNSDGSENSFWCWFYRAALIVKSYFKEVWENNYIEGFIGGEEACSFLLSRNAQPGTFIIRFSDSVPGSISLIVVLNDGTTCRWEPLEFYLQNKYGPYSESFLNLLGAEYSVIGGEIFRYVYPNICKKQAFANFYEKVPDRKVKLKEHYKKIVSVMKTDDEDKDMEDGSSRNQENVLKVLLNNATLNEDMPEPEESSDIRLDSWQNISTPEMVEWMEALAEAHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNQ2</accession>
    <name>A0A1D2MNQ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000778">
        <property type="protein sequence ID" value="ODM94633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNQ2"/>
    <dbReference type="STRING" id="48709.A0A1D2MNQ2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="322" mass="36035" checksum="B11C22BBF3A8311F" modified="2016-11-30" version="1">MKMFRLREVDISEIPKHITAGVKRIKPSGPTDEGLTSEEWEAATEDGVWILQCSKDVNVSEVLTGKKLRLNGRSKIATDDQADEADLTQYVPGSGSLGAIITDRRFETISVPNESGNEGVILLLPDENRFKIVTAPVQGHIIVRESIKNLEVPTIELERPKTRALPAGIKERHPVYGADFTSILKKMEAAPIKSPKKKKKNSGDQEHQLYTSTPSQNGIYSYNGVSSVNDSKQSDSGVKKKKKNQKNHDRSIDDVEDEECAFSNGTLNRSISPIVNISPEASQKKSKKRKREESESFNDFERTDIVEPPVKKNKKTKLRYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNY8</accession>
    <name>A0A1D2MNY8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Striatin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_11951</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000762">
        <property type="protein sequence ID" value="ODM94723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNY8"/>
    <dbReference type="STRING" id="48709.A0A1D2MNY8"/>
    <dbReference type="OMA" id="SPHINKV"/>
    <dbReference type="OrthoDB" id="727118at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051488">
        <property type="entry name" value="WD_repeat_striatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653:SF0">
        <property type="entry name" value="CONNECTOR OF KINASE TO AP-1, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653">
        <property type="entry name" value="STRIATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="249"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="434" mass="48230" checksum="CB8E065D55FB2B78" modified="2016-11-30" version="1">MTLAKYHKLKFGTDPSNELGKPPDLEPEPPELQAAAGSDEPISSQTGRQLLRQYLQEIGYTDTIIDVRSNRVRSLLGLEAPEQQQAQQENGGSLLRIKDLLQNSRDVSPKGFYSFDDDALSNHINNMSLAEAMMMEAESAVMANFDFLQAGMDVDDDDDMADDLDDVDDDINNPSGIADEVDAETEEVLNEFSFLGAEEASLQIRRRMELLGARADDVSLGELAQLTVNNDADMNMDNASLDVEPLYTFRQHSGPVMCLVMSTSGEHVYSASLDGTINAWKVPDINIDPYDSYVRNHTCCHVLLMDCKTVGPTSKTPLLDTFTSTSAIHMAVAYNSQVVIFDLESKKQIVRFECDSIGGSDRSPYPFWDNSTGKMLHAMVAHLDAVTSLAWILMDFIYYLGKMTAHRKKFDEAIHDVAFHLPNLSLHLPGRWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP06</accession>
    <name>A0A1D2MP06_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11939</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000759">
        <property type="protein sequence ID" value="ODM94743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP06"/>
    <dbReference type="STRING" id="48709.A0A1D2MP06"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF803">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="11">
        <location>
            <begin position="145"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="481"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM94743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="544" mass="60340" checksum="DF9A342F440E6F64" modified="2016-11-30" version="1">MFLKTHKISLLQYSLRSFTYRLPQCVRLKRDYHPPHHSVRLFCSALTQDNSLHPSRSFSLFLLLISQKDRSPKDSPSQFSTAFTLLRSAYFSAVNFYLSARTSGVSRFNIIRSVYNSIVEMQVADRLPSPVTEKLSESFENSLVKVGSSSMQGWRTKMEDAHSIILKPRQDRPAHFFGVYDGHGTELFAQDAAQKLFYDWIIKREDYWKGQVKAAIETVSLKSLCIEAFCLYEKSLKANRQFQDLHGGTTANVVLLRNGQVYCGNLGDSRAVACIKGKPFPLSQDHKPSLPSERERIRKAGGIVTPAGRVQFKGHVGSLGLSRAFGDWKYKRAAKSDDQQMVIANPDVTQYTLTSDWEFVVLACDGIWTSKENKDVISFVRERLQQQVEPQLICEELIMSCLATDSTAPHGCDNMTVIIVCCLHGKCWKDYCDKIAGVTVPVPEAGGPVGSLLGADPDPVDDSGDADLVIETPGWIALTRENDTSDQSEGAAGGSSTQSDAGSTQVEPTPDSHENSGTEAHQTAGWSWYIPWHSKPAGDKGNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP74</accession>
    <name>A0A1D2MP74_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_11943</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000760">
        <property type="protein sequence ID" value="ODM94738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP74"/>
    <dbReference type="STRING" id="48709.A0A1D2MP74"/>
    <dbReference type="OrthoDB" id="2129233at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043458">
        <property type="entry name" value="GPR158/179"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32546">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 158-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32546:SF29">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="84"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM94738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="325" mass="36927" checksum="342186746569DEBC" modified="2016-11-30" version="1">MSHHRLGIKKREEQSGSSLSGDSRTGSGNWRKEHNGQGERKSPGERKSKSRNSGSKNRQSSDEVNDDDNQAVIEYFPRVESFAGSHSEEVSNDNSFNEYRPLGPESYSGTNLISTDNSDELLLDDGDSASPLSDTEVPSSSQRNKPDIDIVTRFLNIVESQHLLGENCSAGTDFNLGEGVVDRYAQERFRLIAEFAVNRANMLTRMWKYVNSTVLGNEYLLHAMVMSMVEFDDDIFAAGNCYDQLQYKNYTLFCPFAFRYDGGTVLVKDLSLEYHYLGNSSEWFFIARKNAEKIIQAYNQFNRGKLSEKKTYYFLFHLLSSSFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPL6</accession>
    <name>A0A1D2MPL6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division cycle protein 27 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_11623</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the APC3/CDC27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPL6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPL6"/>
    <dbReference type="OMA" id="GHEFSAN"/>
    <dbReference type="OrthoDB" id="329563at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF13">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="605"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="674"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="708"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="742"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="844"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="360"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="904"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="395"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="904"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="916"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM95050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="982" mass="109009" checksum="B3C8D3232C392962" modified="2016-11-30" version="1" fragment="single">GGLVVLNGNIQNCNGYNVVPGNGVVGVEPIQATIWHCLNNYAYSDACFLAERVHAEAPSDETLHILSSAYYRSGHKTKTYVLLSTNLLKSPHYMTPKNRYLLALVCFELEKYAEAETTLLKSIKHEPGNLASLLDQLERTYGDICAFAIKLYALVCVQTERNSNAFEGFSRCLKLNPFLWNCYEHCCNTMSGTDKIVKNKNIQRVFQLPDSTLQSQSSTMSVTPTPAGAGVPPSSYLPVLIGSTAASLVLQEPQKPESACAPNEPNFNQNNQNYYAKDVSLNSSSNNNFTSSTTTQSTGVLHPSNRNNIKPSKRNLFTSTPMGSGNQGTNTTSFGIIPLLMDSSNASTVNSNTSGGINAAMSPYSPVPSDFEHEGGPPAASGSEPKPKKPCLRTPWQQHQAQPHGSGTPSQMQGTVTISTSSNATVRRSSRLFTHHHSHSHFLKENNKQVQILSTPPSASGNAIGTPESGSGGRRSKKPSAPNSSVLKPKLRLNKSNVGGGSSSTTSSSTVTGETNVEHKCESTLDSSSEFFRIVMEKSEVEAKEIVKSPEVCSVSNIEAFRNGVDPLLHILSNLSAPYTSQTTYNCVIAIAQYQRLKPSQQETGWVVGNVARCYFELGNYEDSIKYYRRMMELEPWRTDGLEWLSTAYWHLQKETELSALAQDLMKSNRTNEVATWVAAGNCFSLHKEHETAIKFFKRAMQVNSSCAYAYTLLGHEYVLTEELEKAMRCYRAATRIDKNHYNAWYGMGMIFYKQERYERAEVYYRKALAIHPNNSVLLCHLGVVQHALGKPEKSLTTFTRALEANTHDPLCKFHRASVLFGIGKLDEALEELEELKEIVPKESLVYFLIAKIFSKKGDTHKALLHFSWATDLDPKGANNQIKESIEPVLNRTGSTVNVLLHNTANATIAQPTNNAEEEEEDDDDDDDDDDDDEEEDDDEDEDDEEEEETQTQEEPNRIIDNLRVTRSNRRSDETNSNNRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPZ1</accession>
    <name>A0A1D2MPZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DPY30 domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dpy-30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000715">
        <property type="protein sequence ID" value="ODM95086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPZ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MPZ1"/>
    <dbReference type="OMA" id="KYKENMD"/>
    <dbReference type="OrthoDB" id="432281at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22966">
        <property type="entry name" value="DD_DYDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049630">
        <property type="entry name" value="DYDC-like_DD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037856">
        <property type="entry name" value="Sdc1/DPY30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23356:SF16">
        <property type="entry name" value="DPY30 DOMAIN CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23356">
        <property type="entry name" value="DPY30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="294" mass="31926" checksum="C61BBE5D8F041816" modified="2016-11-30" version="1">MAEQQQQPQSAKAQMLNDRTYQEVEYLKRNLGPILVAALAEICIRRPADPIEYLGHWLLRWRYNEELKRRDVENALEVVKQKAWTKDDEKLTPNPAAPDQPPAPQQFTQGFLPGAPYAPPGYGGPLDPNAVEQLAPTEDITAQPTATDTAPSTTVPEEPQVEGEAALEPTGDAVEERRGSQSGEKRPSGEKRSSVGERGSNAEKRPSQPGATGSGEVQRSSGADVPTGEARRASIDKRTSGDRRASLQEEKRPSGELQQKRTSGDIQVDANNPEEPTPSAEPEPTADAEPAVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQC3</accession>
    <name>A0A1D2MQC3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_11419</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000693">
        <property type="protein sequence ID" value="ODM95267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQC3"/>
    <dbReference type="STRING" id="48709.A0A1D2MQC3"/>
    <dbReference type="OMA" id="RSMIDHA"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000019">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="10">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM95267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="256" mass="28066" checksum="ABA14F02C06E8F9B" modified="2016-11-30" version="1">MNGGLKSAKMFLTRSEYDRGVNTFSPEGRLFQASKLQVEYAIEAIKLGSTVIGICTSEGVVLVVEKRITSPLMEPSTIEKIAEVDRHIGVACSGLTADSKTLIDRARLECQNHWFTYNEKMTVESVAQAVSNLAIKFGDSDDDEGAMSRPFGVALLFAGADEKGPQLYHMDPSGTYVQYDAKAIGSGSEGAQQTLVEMYNKSMTLKEAVKTSLTILKQVMEEKLNSTNVEVSIVTPKDNFHMYSKEEVEEAIKDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQD4</accession>
    <name>A0A1D2MQD4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cullin-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11722</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 12">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000728">
        <property type="protein sequence ID" value="ODM94965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQD4"/>
    <dbReference type="STRING" id="48709.A0A1D2MQD4"/>
    <dbReference type="OMA" id="PRPVWND"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031462">
        <property type="term" value="C:Cul2-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000012">
        <property type="entry name" value="Cullin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000016">
        <property type="entry name" value="Cullin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000022">
        <property type="entry name" value="Cullin-2 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1030.10">
        <property type="entry name" value="Ring Box Chain A, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="13">
        <location>
            <begin position="395"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM94965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="749" mass="86801" checksum="B587B839BF2BBBD4" modified="2016-11-30" version="1">MSLRPKQVNFDETWGTLRRTIEGVVTLSKVPRVEWNDRFTDVYTLCVAHPEPYTNQLYNETQVFLRKHVQALRTEIEKYESNSSLLKVYYDMWIKYSQGVEYLNKLYSYLNQQHVKKSKLSEADITYGGVTDMPGHMIEIGELGLEIWRQDMLEKIQDTLIELVLEAIRSDRRGDTAVSTTIVNGVVHSFVAVEDPKHRIPGDPHTHLTFYEKAFEAPFLQDTGRYYQQEASKLITTCSVSEYMEKVIQKLNEEDMRARRYLHASSYGKLSSECHRRLVSDHLSALHSECRIMVENDRRQDLTNTYGLLKPLASGLNVLADTLEAHIKKEGLEAVSSLKQETAHMDFVESIILLYKKYKDIVNTVFKSDQMFISSLDKACTAVINFRQCTKNPCRSPELLAKYCDALLKKSTKGYSETEVDEKLSQSIIIFRYIDDKDVFQKFYSRNLARRLINHLSHSMDAEEGMINRLKQACGYEFTNKLHRMFTDVSVSSDLNNKFNDYLTKEGIKLPISFSIMVLQAGAWPLQQNPSPFAIPQILESSVQKFETFYGRQFNGRKLTWLHHLSSCDVKLSYTKKPYFIIMQTFQIAVLTSFETQDEMVYRDIREATRLTDDQFSRHLQSLIECKLLECDDKEFTQDSIIKLNKGYSNKRAKFRISGAVQKETPQEVEQTHVSVEEDRKIFIQAAIVRIMKSRKVIKHNVLIQEVLQLSNGRFSPTISVIKKCIETLIERAYLERTPNSADEYSYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRG2</accession>
    <name>A0A1D2MRG2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_11209</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000666">
        <property type="protein sequence ID" value="ODM95481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRG2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRG2"/>
    <dbReference type="OMA" id="CSHEPIR"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000021">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="10">
        <location>
            <begin position="66"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM95481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="432" mass="49484" checksum="55B229581E412C98" modified="2016-11-30" version="1">MSCGLKMDSHKHSFVCIVISIVLPFLVTFSSCDDSFPVFFEFTSGYGITGDSLSPYFYGSDADLSVPQLIHKYGFPCEIHHVTTKDGYILELHRIPFGTKSGSGPKPGKDVVFLQHGFLASSADWIMNTVDKALAYELANHGYDVWLGNARGNTYSKNHTDLSPKDSKFWKFSFHEMGAYDIPAVLDYVLNTTQQPNLFYIGHSMGTCMFWITMQMYPEYNSKIRNMFALAPIAYVEHIKSPIRILSPLSTEAELVTEIFGDREFLPHDGWITLFRKIVCSHEPIREALCANIIFLLSGFDKKELNETMLPIILAHTPAGASTHTIIHFAQYINSGKFRQFDYGKRENMKIYKSEEPPKYDLSKVTAPVSLYWSDNDWLAVKEDVDRLKSQLPNVNDYFRVNYTQFTHLDFLFAIDAHKMVYERILESMKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS05</accession>
    <name>A0A1D2MS05_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Endocuticle structural glycoprotein SgAbd-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10789</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000610">
        <property type="protein sequence ID" value="ODM95889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS05"/>
    <dbReference type="STRING" id="48709.A0A1D2MS05"/>
    <dbReference type="OMA" id="DQQSAYT"/>
    <dbReference type="OrthoDB" id="6372059at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF241">
        <property type="entry name" value="CUTICULAR PROTEIN 47EG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904445" evidence="4">
        <location>
            <begin position="17"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM95889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="16959" checksum="50B2747E17C9A536" modified="2016-11-30" version="1">MKSFIVFSALVCLAAAQFGRPRQQASAPRGGEEVLIIRSESENNGDGTYRYLWETSDGTQAEESGYLKPNGNDDPIQVAQGSYQYYSPEGQLISLQYIADENGFQPTGDHLPTPPPVPAEIQKALDLIYANNAAQGSRPSRPQSGVRPPNRRPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSD0</accession>
    <name>A0A1D2MSD0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000615">
        <property type="protein sequence ID" value="ODM95822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSD0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="379" mass="42444" checksum="D86A2D6F5FD2D9EC" modified="2016-11-30" version="1">MPISNPEDAIISGFKRVCKRKKNHDNKLTSPEEPICECPITKPDGDVSETIEISDDSTVIAKAQVIELNEPKPKELEAKNKSEFDEALLPSPSASFLSVDSRQKDLDEQSKSSTDSAGSYLSEEPQDSHKNIPKLGNEDQIVLADQNDKINAIVNQVIKAVSVDNEQVKVKTNTISSERRNGQVGDRRRNTWLPCTCPQYKVSCELATKCNAQALFFAKMMVVKWSIPCPVNVHTYNDVISRSVAKICGFDCDTSIDCNYCIYLHLCHSNLQLCPPPVGNCYCAVNLFDADLYTKFVMHRITNFAGFGLTIVSSVVLLFLKELESKELTYIQFVSHVWLPALLLSQLVVMVSILEIQRMLFGLSFNVSTKRWHIAALYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT59</accession>
    <name>A0A1D2MT59_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000583">
        <property type="protein sequence ID" value="ODM96078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT59"/>
    <dbReference type="STRING" id="48709.A0A1D2MT59"/>
    <dbReference type="OrthoDB" id="6428908at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF18">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="328"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="493" mass="56887" checksum="979C31BF919AD3DD" modified="2016-11-30" version="1">MERKQLEYRYFLDQHNEYDSRVSILDDETLRLSLVIDDDDDSHPGELSAPSLHLVEPKVYLRFSGESGMIRPIDSYKDQNNVVVSSQNVETRDRTRINPHHHETEIEEDQDTECDNYIDPLLQQQLQLLSQNKFEEGLENVVDLNDEHSKYFVKTKPRSETVSRNNIYSNFYYEPPSFSTKSVLIPVKTNRKLFVFASAKPPTQNSHHENSHNHDDTELSHQDRTTTFPNDDSERSYEIQAQQNNAKNKTLDVFTSQSILSKVTLNGSKANSDSKMLEREETSVSSTAASISSGTSTTEATTTTTDATSIPGTPGVDYPIFYEIPQTGFDCKNQRYKGFFADIDTKCQAWHYCDFTDGHSTFLCPNGTLFSQVLLTCDWWFNVDCDQARQLYVLNERLYRYIKPPKPSFPEDFTGEHVDKWLIQQWQMGLLPKVRKRSKAKLATLPPPRIPSCSRSRKLKKKYYLRFPNVITVLCNFMSASNHFTDTFITSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT86</accession>
    <name>A0A1D2MT86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathionyl-hydroquinone reductase YqjG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000578">
        <property type="protein sequence ID" value="ODM96108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT86"/>
    <dbReference type="STRING" id="48709.A0A1D2MT86"/>
    <dbReference type="OMA" id="PWANRAI"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01148">
        <property type="entry name" value="Xi_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="182"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="139"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="157"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="341" mass="39379" checksum="480D350663C4C78D" modified="2016-11-30" version="1">MKRKSAPIAYCKLLNCSYFKMSYMSLNSIKDIIGEKGDFQRKSSVFRNTISKGGPFPPEADRYHLYISLACPWAHRTLIVRNLKGLDHAIGLSVVHYLMLENGWEFANSDVPGCIPDTVNSFKMVRELYFQSDANYAGRFTVPILYDKKTKCIVNNESSEIIRMFNSEFNEFAKNPELDMYPEALRSSIDEINARVYDGYNNGVYKAGFATSQQAYEENAKLVHDTMVWVNEILSDRKYLCGDALTEADIRLFTTVIRHDPVYLVHFKCNLVAVKDLQNLSRWVKLIYQNERVQETVNMEHIKKHYYMSHKHINPSAVCMLQRNPIDVTVLAMLINYLSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTB4</accession>
    <name>A0A1D2MTB4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein sel-1 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000556">
        <property type="protein sequence ID" value="ODM96283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTB4"/>
    <dbReference type="STRING" id="48709.A0A1D2MTB4"/>
    <dbReference type="OMA" id="SLAYWRL"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="649" mass="71401" checksum="018491448AA83E06" modified="2016-11-30" version="1" fragment="single">LTLCTVNGIELNENARSRKSSKESQEKSDVPPPSDEHDTIQIVISNTNQPDEEGSTEEEDSPKIEDERNKIKFVLDKQFVFNSFQQSPVDPIGATSSFRGSVGKRNTEIPGDWAYDVAGEDDAQMKQDALTRFNEGLSTLFPIPQKSEETVPKATPSLLSTSVYIRTSVGKSVQIAKAYENFKIASPYHHNSRELIAYANLLGQHGVPFSIPKAYDLFANLSKLGYPNSQFAMGLFSGYGLVGKMDPAVTLLHYTFGAVSGSAFSSMALGYRYWGGIGVQASCERALEQYRTVASIVASEVSEAGVGPAIQRVRLLDELEGDRGTSTSSGSNVLNSDILDYYTMLAERGDVQAQLHFQGGRGISPDHHLALRYFQRAADAGSPVAMAFLGKMFLEGNDAVEPDYNQALRWFQRAAEQGSPVGQILHHGRRAGILTQSNNNNLIHPRFVGWVDGQLHLGNMYVSGIGVRRDYNLAAKYYNLAAQSGHILAIYNLAQMHATGTGMMRSCTAAVELYKSVAEREAYTHYQEKRFSNALILYLLLSELGYEAAQSNAAFMLERGEIGEQVYSLLNSSNITPNVLLSKALQQWARLASQGYSPARVRLGDYYYYGWAPTEITRMPPLSTESLLRATGTPRPCSTWRTCTRTGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUK1</accession>
    <name>A0A1D2MUK1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter G family member 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_09988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000511">
        <property type="protein sequence ID" value="ODM96686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUK1"/>
    <dbReference type="STRING" id="48709.A0A1D2MUK1"/>
    <dbReference type="OMA" id="WARTSAI"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038:SF3">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 20 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="589"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="633"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="668"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="758"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="78"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM96686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="785" mass="87174" checksum="8E34D187D9A7E3D4" modified="2016-11-30" version="1">MEDTEQKYENPGFEAGPEEIGMANLNGNAAAVLATTTTTVAPSNGAAAAATSISMPKEATTRIVNNTRSAEWNANNAVVIRNAMKTYRGAKSPVLNDFNMTVKEGTIYSLLGSSGCGKTTTLSCVVGLRKLDDGSITVFGARPGTKQSGIPGRRVGYMPQDICLYEDFTICETLQYFGTICGMTKDEIEDQVDFLIDFLDLPPAYRTVRTLSGGQKRRVSFAAALIHSPELLILDEPIGLMRSGRLLAEKSPDALLQEYNTNLLEDIVLKLCKNDTMGITEEEAAKQNEEDDPVAQAIEEISFQSQARLSITAMSPNNASAPRFRNSTSKDGPGSPVLAPKVSTNPQPPQNPHKLEKSLSSRSVISYKRKQSFKQDIHDEIYLGFSRLKALVRKNLILLMRNRKFLFFVLILPCIQMMNVCVTVGNDPTDLEVGVVNFDSDCKNYSMDDCIPRHLSCRFLDLLPGQNSQNRTLKLIPFDTEEEALEQTKAGKTWGFMVFPENYSTYMYERAISGAEPTEEVLNGSIISFEMDMTSKQVAETIRTTFFFTFQKYIIQLFESCGFDRRVGEIPLKLEEPIYGSTDTNFRQFLAPSAILGIIFFCPLITGGVNHISDKKRGTLDRGLVSGVRTVEILVSYFITEGIVLVVQTLLIFLIITQLFTIEFNGPIYWGIILSLLIGFCGLSLGFLASTFCTEEVQTILVSIGSYYPNMVLSGMVWPLEGIPKFLQYIAYLVPCNMACESMRSLATRGWGIDHPHVWPGFVSTIGWILLYWILTILVHKTVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVC6</accession>
    <name>A0A1D2MVC6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium-dependent phosphate transport protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_09819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Apical cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC34A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000496">
        <property type="protein sequence ID" value="ODM96861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVC6"/>
    <dbReference type="STRING" id="48709.A0A1D2MVC6"/>
    <dbReference type="OrthoDB" id="76259at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM96861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="111" mass="12238" checksum="6254FBEE3F6EFA4A" modified="2016-11-30" version="1">MDYGCKIGNSANHGIGDREQFRRAFAGATVLYMFNWISVIVLLPVEVITGYLYHASKATVDLIIPDSQSGGEIQNSLSHNKSIRRSHSSNLTILYWNAGLLQTALTLMTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWS9</accession>
    <name>A0A1D2MWS9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear pore complex protein Nup50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000459">
        <property type="protein sequence ID" value="ODM97254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWS9"/>
    <dbReference type="STRING" id="48709.A0A1D2MWS9"/>
    <dbReference type="OMA" id="SPCVRDY"/>
    <dbReference type="OrthoDB" id="10062131at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13170">
        <property type="entry name" value="RanBD_NUP50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="436"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="559" mass="59799" checksum="2462E48DCBA0BBB9" modified="2016-11-30" version="1">MQPFKYLGTGNIVKIGKIKVKRSAPESSSEYSDSGVNQRTLGEYQRGSAMPKRKALGPVDSSDGEDDAFYSFPSTPMQSPFPKQIPNNFHSSSTPKRLPPTSNLTTFSLSSNSSGTQLQTLAATSGLQNKSSMFALSTNQISSSVPPAPLVAKKPRSSEFTKSMRDLNNAFVSSCRASVSKNPTHSLVPLVKDYLHHSRVLMEKSRGKTVGENGPTTKLVNGITPSPPPSFKTLGEFFDDFERNFTESTAKDDKSESRKETNLNTSGAITNSNSLSAFLSSGKINNNFGLTMSSPKPASENFKAFGSSETVTASSSSTPSETTSVKTSMFMSSPSPAKVSTLTDINKSNTSNVLSPALDLGSSGPLKSLTSPALSTTTKAEPVKVSEPAAVTKPAPFSGFSFFSAPPQSTLGGLGSSAVTSSVQKNNEEEDGEEDDEPPKVEITQVTEDDAVYSARCKVFGMVDGKYKDKGVGMLYIKKLSGGKHQVVVRADNNLGTVILNILLQKSLPLDKKSAKDVMTIDVHGNNNKGMPILLRVKSEADATELLNKLKEYREMNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ65</accession>
    <name>A0A1D2MZ65_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Putative ATP-dependent RNA helicase YTHDC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_08388</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000366">
        <property type="protein sequence ID" value="ODM98290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MZ65"/>
    <dbReference type="OrthoDB" id="6103986at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17358">
        <property type="entry name" value="MFS_GLUT6_8_Class3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000055">
        <property type="entry name" value="Facilitated trehalose transporter Tret1-2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044775">
        <property type="entry name" value="MFS_ERD6/Tret1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF213">
        <property type="entry name" value="3'-5' RNA HELICASE YTHDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="16" id="KW-0347">Helicase</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1374"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1416"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1447"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1473"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1508"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1533"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1624"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1659"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1688"/>
            <end position="1709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1729"/>
            <end position="1748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1791"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="13">
        <location>
            <begin position="34"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="194"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="478"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="559"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="1376"/>
            <end position="1814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM98290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1884" mass="211538" checksum="86E6CA6DEAC10990" modified="2016-11-30" version="1">MPRDRGDRGEERAPGEKTSGDIKRLKNIVGKVSEDVKIRLDYLIQDFLARSELPDITFPKLLSNIERAYVHYQATKHGLKSFSTGTGPERRLTLTRAVETTGKRLKRFSFTEECIWGISNLMAKYPDFFARPVAGQSTSQNQNFRSNGNVSLKGVHASRISAGPSPKVPKQRMAQDFLNSRKQLPIWNHQEQILETLEKHRVCFIKGATGCGKTTQVPQFILDDATRKAKNVRIICTVPRRIAAVSVSERVAVERGERLGQTVGYQIRLESRYSPCETLLTYCTSGILLRSLSSPNYSVVEKTTHIIIDEVHERDRQTDFLLACLRDIIVLFPNLRVILMGADLNNVLFSTFFGGEFNCPTIQVDGRLYPVQAYHLEDVLEMMNYENYEMRSTRQTDDRAKIYNQMVENLQNVQLASVKPRCYNGVSISVDTGEVLVRPDVDELIQQVWTEGDEYSLAEYFHMVEGNDVSVNYQHSTAGVTMLMAAAVRGEIEWAEKLLKYGADINIKSKYEDTELCATDWASDHRQHKMLQFLLEHKYNNALMPAVTAQSMNSKKLQRLTSYLRSVDEERVDLMLILRLLHQIHINSDYSDAVLVFLPGYDEIVNLKHYIISDRELGFHPGTFNIFMLHSNIQTGDQRAAFEKPKRGVRKIVLSTNIAESSLTIEDIVYVIDSGKAKEKSYDSMTGVTQLKSGWISKASVNQRRGRAGRCRPGICYHLFSTIRYESMSEFPIPEIIRSSLQELCLHARSFIRPDLKIEQFFMRIPEPPAPIAVRKSVEILTVMGALDENERLTKLGMHLVDFPLEPFLGKALIYAIVFKCLDPILTLVSIISYRDPFQLPSDPLDKEKAQKCKVRLAEDSFSDHMAYLKAFHDWEGSKSSFQEGTVRRFCRDNYLSAVTFEMVCAIRSQLLGQLRASGFVRNKGRGDLTELNTYSNNWPLVKGVLVATLYPNICGVDLDHAKKVLYNGFNNKIAFHPSSVLTKKGNTVPEVKSEWIIFDEMTQQGSVNLVKGCTCVSAAAVALFAGSFSTATTKTNEFEISNQGYPFFIFKINQWMSLDATKDTLELLMPLRRKINDLVVKRLNSPSAYLTEEEEATIAILSSVLYHEDVALGFKNVEKVGQWPKFVSGNFMSAPRTGFVKPKGGNFAPGSLIPYLIRPRFFSVEISNATQVVDLARSSVWLVPESVSKKFWCITKFEKENVGDVIIFFWFPGTSEFVGAMKVDSEFRMVRLPEVPAQVFSDKRISLTNVDLVTKVGFKSLNQPMDGLEMDYEVGVMIMKMFEEMQRFRNRNVWQCYRLKSAFISGDSGTCSLSSTSSAFLQGQRNSCSPTNKMQTVHATIPKHMAAVVKPKAVLGDHVPSSPPSFKKCRNQILATVIVTIGSFGTGTVFGWSAVATDDLKKSGDFGVISQENEISWVTSLAILGAFLAGPLAGFLMDRCGRRRSIIIFSLPFALGWIVMCSAWFSKPHGFYLLYIGRILTGICAGSYLVIIPTYIKEVSIDSMRGVLGSAMPLMLVGGILYTFTLGTFCNWALLTALCGIVPILLAIGLCIIPETPRYLIVKNRRDEAVRSFKWLNRIESYADAEAELDYICSTQSITSVNRNRSPKSNWKELMTPPVAKPIYIILFVVFFQQFGGVNAVTLYTVEIFRGAGDFIQPHVATIIMAIVQVVFVILSMILVDILGRKTLLVICNLIMGVSLFGLGFYFYMKEKGDGSETNISWMPITTILTYIAAYSTGVGPIPWVLGSEIYNPEFRAESSTIMTSAYWIFGFVVSKTYENIKIGFRESGSFWFYGAFCIAGALFSLLFVPETKGKSSEEILKHFGGQMYKGAGDANHNCGIISDSAKLSPSLLLNPKPDMHTETSETDILSNNGEIHKTVSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZS1</accession>
    <name>A0A1D2MZS1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000353">
        <property type="protein sequence ID" value="ODM98451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZS1"/>
    <dbReference type="OMA" id="FITEATC"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904803" description="Ricin B lectin domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="21886" checksum="37915115F16DB873" modified="2016-11-30" version="1">MNSFSFALIFGLVAISQAQVPTLIESTLDGKVLTITNKTVPPTGPYQRLGVAALDVDNSQGFPQYWAFDVFGGDINRGQIGPVNGVVWNSLTAYLPCDDCFAYFYTYDFGQIVSNGSRLLKRIDTDSCVQNPGNGGFITEATCNETDVSQLWIINNDSITTNVNHDSIEDNSVSSEELNIGEHKSSSTSDEQSSASTSDEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZS6</accession>
    <name>A0A1D2MZS6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selenocysteine-specific elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000364">
        <property type="protein sequence ID" value="ODM98324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZS6"/>
    <dbReference type="STRING" id="48709.A0A1D2MZS6"/>
    <dbReference type="OMA" id="CFAIKGQ"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04094">
        <property type="entry name" value="eSelB_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03696">
        <property type="entry name" value="SelB_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000052">
        <property type="entry name" value="Selenocysteine-specific elongation factor EF-Sec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049394">
        <property type="entry name" value="eEFSec_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049393">
        <property type="entry name" value="eEFSec_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF11">
        <property type="entry name" value="SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21131">
        <property type="entry name" value="eEFSec_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21208">
        <property type="entry name" value="euk_SelB_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="18"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="536" mass="59418" checksum="52B024E26C6F5AAB" modified="2016-11-30" version="1">MSSENAGAPSQEGVPLKKTNVSVGVLGHVDSGKTSLCKELSITASTAAFDQNPQSQERGITLDLGFSAFTLEDKWNVTLVDCPGHASLIRTVLGGIQIMDIMLLILDVTKGMQTQSSECLILADVLASHLIVALNKVDMLPVESRQTKIDKAKKMLKATLARTKFGENAPIVLCSALDKSIGVDTVKEAILDKIKAMTLVRYEDRPFVIAVDHCFQKKGQGTICTGTVIQGTVKIGDMVELPEQQIQRKVKTIQSFKVPLTSAVAGDRVGMCIGAFDSSLMERGIISAPGHISVGTRYVLMKLHRIKYYKHSITSKSRFHISIGYETTTAVITLFEHPKENFDFQPTIDYNYVDELSPEEKGEKTFFAVLEFDHPVTTLQHVKIIGSNLQIPPNSNECRLAFYGEVERSCQIKDKSNFLAQIKIYKIKKRQGILDRVTNSRTVIVRGLHQKSSNIDHLLGCKIDLSFGPESESTVVQGTIESRFGQTDKLRVNLNEDLSDIQMDKCKQKQVEVSLVHKKYVFKEEGVNSAKKLIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZT8</accession>
    <name>A0A1D2MZT8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 4C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_08351</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000363">
        <property type="protein sequence ID" value="ODM98334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZT8"/>
    <dbReference type="STRING" id="48709.A0A1D2MZT8"/>
    <dbReference type="OMA" id="LRINPIV"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="524" mass="60959" checksum="173750380C9B0DE9" modified="2016-11-30" version="1">MKSFDYPHFHKYLGNVLLRDFRLGFVLASLFKTIQKWIVSWNGNSKHNERDLNRYDTYKSLPGPRPFPLKLIGNGLSFLFERDILKAVINMAVKYGPYYKLIFFNEEIVMLNSPEAAQALLMSSDNGHLGKGRIEEKIFPTELDSMLKWRGGEKWRARRKMLTRPFMYKSLQMHFNCFHKHCERLVSRLENKFSDNAATGVALESLKQCIFGISSETLMGVDIENSEDGIHFCNNLDQIMNLMTLRAYRPWLLIPALWTLSAEKRRMKKIIDDMKKVIHKVMEKYREKVSAGEGDADELSNTMIEVMLRNGESEKSIFDELAIMLTVANESTPYVLELALFLLACHPEHQELCRQEIDEVFQDPFMLKNGVLKFDALKELKQVERCIQESLRINPIVTIMRRLESPLKINEELVIPKDVSVVLSAYVLHHLPQYFPNPEKFDPDRFLPERVRERHPYSYIPFSGGTRSCIGLKLAMMELKTIVAIVLRNFEVGTPDTMEELQFVANPTTKPSRPFRFTFKKRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZU2</accession>
    <name>A0A1D2MZU2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Proclotting enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08173</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000347">
        <property type="protein sequence ID" value="ODM98508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZU2"/>
    <dbReference type="STRING" id="48709.A0A1D2MZU2"/>
    <dbReference type="OrthoDB" id="546450at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="10">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="10">
        <location>
            <begin position="420"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="611" mass="65552" checksum="F1A770757A66F0A5" modified="2016-11-30" version="1" fragment="single">MLNGRQFCGGSLIDAQHVLTAAHCVYFMNRGDVSRLRVQIGDHNIYSTSDGQHQVRGASNVYFHRGFSMRTLYDDVAVIRLGSPVSYNRFVQPICLSTNSWGLENFVANVAGWGQLSNSGSQSSVLRTVGVRIWKQPDCMRTYQGRAPAGITNGMVCAGGSGYDSCKGDSGGPLSVTRNSRAEQIGIVSWGVGCGSFPGVYTGYVGGEAVKTKVDVLKNYTNMRFLIIFAIFSIAVAFGSELDIIDFSSDDTVVVEALDDETEASATTTLPVEERVEDSLDGSKSRQELPNNYCVTNTGLSGTCEPVQECFPRLFPVKSSDDSESDDDTPGQTGVYNQVLAKLLIEASGFCGSSRDAPTVPLAVRNTGRVCCATSKVNETFPLEDPSSSNDTSAIEADYLKKPCGYIKVDPKTLPNPEKVVGGRPAGLGEFPWQVAMLRRGQQFCGASLLDSKNVLTAAHCVEFMTQNDVKALRLHMGDLVLYTNSDGQHVERKAKRVLYHKGFTMKNLDHDPVCLHPGNPAYDTGSTEADVSGWGTTSSGGSQSSKLLAVKLRVITQSECNQKYSKVGKSVGPGMVCAGSPGKDSCQGDSGGPLVMDSRGQAKQIGIVSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0S8</accession>
    <name>A0A1D2N0S8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000313">
        <property type="protein sequence ID" value="ODM98893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0S8"/>
    <dbReference type="OMA" id="TANRCHI"/>
    <dbReference type="OrthoDB" id="10574120at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904843" evidence="1">
        <location>
            <begin position="27"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="234" mass="26708" checksum="FE7EBF2C00FA9F9F" modified="2016-11-30" version="1">MNTRNSSIVSILIFCVLLNTCPFGDACLKKIRTLIRNKGKEETPAELARDESLYTKYSHSSSDNVYIEILQSENKTFVLREYDHPPVAMSQVRQSEEPDAEYVNLNETTNGTIPTTSEAIPPERAAPEISEDEVTEEPLSPEDANIRKEWGGNCMVSDWNRCNKVREIIVQNVINNQFQTKHLELDCLLEPILCLTNGWTANRCHIICMAKCNKALFFDWDGVVDFEGPCRYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Z2</accession>
    <name>A0A1D2N0Z2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="26">Dynein heavy chain 6, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">Ocin01_07699</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000306">
        <property type="protein sequence ID" value="ODM98966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N0Z2"/>
    <dbReference type="OMA" id="VESFDWQ"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000002">
        <property type="entry name" value="Dynein axonemal heavy chain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000005">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001145">
        <property type="entry name" value="Putative dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF68">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain linker" evidence="17">
        <location>
            <begin position="1095"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="18">
        <location>
            <begin position="1626"/>
            <end position="1952"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="22">
        <location>
            <begin position="2118"/>
            <end position="2240"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="23">
        <location>
            <begin position="2459"/>
            <end position="2542"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="20">
        <location>
            <begin position="2604"/>
            <end position="2862"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="19">
        <location>
            <begin position="2878"/>
            <end position="3207"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="21">
        <location>
            <begin position="3236"/>
            <end position="3456"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="16">
        <location>
            <begin position="3708"/>
            <end position="3823"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="24">
        <location>
            <begin position="3851"/>
            <end position="3925"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="25">
        <location>
            <begin position="3932"/>
            <end position="4247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="171"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="3099"/>
            <end position="3147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="ODM98966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="4252" mass="486600" checksum="4871EF7EFDF5CDC4" modified="2016-11-30" version="1">[encoded data, 4252 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N175</accession>
    <name>A0A1D2N175_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000303">
        <property type="protein sequence ID" value="ODM99029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N175"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM99029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="298" mass="33483" checksum="6EE15E931A44A3C6" modified="2016-11-30" version="1">MQNNDGLLDEETVTGGATRNDSTIIQASRPPRSRVRRRVSRSPRSRVRRRVRTPSTITSVFRRTPSSIARAPVSTLNLTDLHQFRENLTTGYLGEALIQSFLDREVQANNDGLLDENTVTGGATRNDSTIIQASRPPGSRVRRTVPTPSTITSLFRRTPSSLARTLFSTHNLTDLYPLSRNLAAGHLGEALIQSFQEREVEVLLPSCLNILVRSSGFDEPLLPKKIRKKKKRIQLEDPPETERDMEWLCYTGSETDTEALVIMIVTLAIWIEISQVDFAGWEKPQPKDKQQAPLAEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1M2</accession>
    <name>A0A1D2N1M2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Enoyl-CoA delta isomerase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07487</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000294">
        <property type="protein sequence ID" value="ODM99186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1M2"/>
    <dbReference type="STRING" id="48709.A0A1D2N1M2"/>
    <dbReference type="OMA" id="WFPGVAD"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="319" mass="35790" checksum="24191D9681464EEC" modified="2016-11-30" version="1">MAFTSLRLTQRFLKNQKVLAFTGICKTVPFAVTALGLPSKCYFHHTKEYSSSSPSTSTDLLVSVQNGVRTITFNRPSQKNALTLDMFRGIIKALHESNTDENTTIVAITGTGDYFTSGIDMKSSYKKGIDNNPTEKAENRTVETQQEPKKRSRLFPFLNAILSCKKPIIALVNGRALGVGVTILGLMDGVYASESATFQTVFTKIGLIPEMSSTYTYPRIMGYCRANKILLWNEKISAKEAYECGLVSRLFTEEEFGNVKDILVEYASNPVNSLVYTKQLVRGREKELLHQICEDEQQLFDPEMAKKAKEQFLTRKTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N456</accession>
    <name>A0A1D2N456_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tropomodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N456"/>
    <dbReference type="STRING" id="48709.A0A1D2N456"/>
    <dbReference type="OMA" id="PYQRDKL"/>
    <dbReference type="OrthoDB" id="2163268at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005523">
        <property type="term" value="F:tropomyosin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030239">
        <property type="term" value="P:myofibril assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051694">
        <property type="term" value="P:pointed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000099">
        <property type="entry name" value="Tropomodulin, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004934">
        <property type="entry name" value="TMOD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10901">
        <property type="entry name" value="TROPOMODULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10901:SF6">
        <property type="entry name" value="TROPOMODULIN, ISOFORM N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03250">
        <property type="entry name" value="Tropomodulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="42291" checksum="A14195A234D54A14" modified="2016-11-30" version="1">MSDATVTTTKTTTMTTRKLYGRDLSEYDNMDVDELLSQLTPEELDILSREVDPDDSLLPPDQRTSYFCEKNATGPLDRKQLIEHINKIAMETPDRPELKPYVAGTVRGKKWIAPEKPLTKQEEEIRVDMGDEYESALSSATEEEIVDLAAILGFHSMMNQEQYHASLTGKAQVKGGWNGVAKGYVPKALPFEPPNMTDVEKSIKQLEEDDYNLTNLNLNNIHLSDQQFAAMFEALKTNTNLDTLLLCNTGLTDRSALLFAQALETNCALRTISLETNNVSAAILAVLFKAMLATKYIEEFRASNQRQQVLGNKTEMDITQLIEQNPTILRVGLHFEYNDARNRVATHLQRNLDRTRLRRMGRAPRNNMTITGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N464</accession>
    <name>A0A1D2N464_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein CDV3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDV3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N464"/>
    <dbReference type="STRING" id="48709.A0A1D2N464"/>
    <dbReference type="OMA" id="VMICERN"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026806">
        <property type="entry name" value="CDV3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16284">
        <property type="entry name" value="PROTEIN CDV3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16284:SF13">
        <property type="entry name" value="PROTEIN CDV3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15359">
        <property type="entry name" value="CDV3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="196"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="28295" checksum="5D64931545B61BE4" modified="2016-11-30" version="1">MADLDDFFAKRDKKKTKGKKFDTTEDLAKVLDQRVKEKKKLETGKSNYAQEGGRNSPGPGLPAGDDDEWLEAEDKAPDYTGLKIQELVLSDEDEEKEGEEGKGSGDENDKEGPWKKKERKAKEEEAAQKEAAILKEAALKEAAQKEAETEETKEKEKTEEKSEGVTEEGGEVGSKEGENVESEKKAYVPPSKRQQESGAPASSSSSEPPKPVGSGSAYVPPSRRGAGGASSSSAPLGAASSVPKKKQPGHVPTLGDEESFPSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4V8</accession>
    <name>A0A1D2N4V8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000214">
        <property type="protein sequence ID" value="ODN00317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4V8"/>
    <dbReference type="STRING" id="48709.A0A1D2N4V8"/>
    <dbReference type="OMA" id="QRPHYRK"/>
    <dbReference type="OrthoDB" id="1703270at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11380">
        <property type="entry name" value="Ribosomal_S8e_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.70:FF:000004">
        <property type="entry name" value="40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.70:FF:000005">
        <property type="entry name" value="40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_eS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018283">
        <property type="entry name" value="Ribosomal_eS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01193">
        <property type="entry name" value="RIBOSOMAL_S8E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="23591" checksum="A80A108FE96DF65C" modified="2016-11-30" version="1">MGISRDHYHKRRATGGKRVAIRKKRKFELGRPAANTKLGARRVHAVRTRGGNSKYRALRLDTGNMSWGSEGITRKTRLIDVVYNASNNELVRTKTLVKNAIVVIDAAPFRQWYESHYGLPLGRRKGTKMSEAEEAIVNKKRSKKVVKKLKLRQKTAKVDPALEEQFQTGRVLACVSSRPGQVGRADGYILEGKELEFYMRKIKAKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N695</accession>
    <name>A0A1D2N695_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7064 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000186">
        <property type="protein sequence ID" value="ODN00790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N695"/>
    <dbReference type="STRING" id="48709.A0A1D2N695"/>
    <dbReference type="OMA" id="HSFGTER"/>
    <dbReference type="OrthoDB" id="5798273at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055492">
        <property type="entry name" value="DUF7064"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34717">
        <property type="entry name" value="EG:BACR7A4.20 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34717:SF1">
        <property type="entry name" value="EG:BACR7A4.20 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23212">
        <property type="entry name" value="DUF7064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905101" description="DUF7064 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7064" evidence="2">
        <location>
            <begin position="282"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="430" mass="49715" checksum="17E791E36DC830F5" modified="2016-11-30" version="1">MLCCCLSWLFYVGIFLLLGVLLSNKDPPKLAGVYSQPGKYYWPKVVLFYLLMKLRKWKDNRNTEAQKDHTKVETYNSGYGTKSKCSPAEMDKVQPLSDHFQAIDAIYFNGADSNGFCIITGTARRPHDVVNGFLILRIPELGYLVSPKFPDCQLFGGSDEYYGAEGFRYEPVVPMKHWKLQYNGQMKSSDDASKTFEVRLNADWKSDLEYFDYDTDVPPWTMARAIAKEPWSREYFQQLKEAHQTHYEQHGTISGEALIDGKVYKFSAPSMRDHSYGVKRNWKLLYRYMFHMFSLEDGRRFDVGNVCQPVTASHLELGYMYDFDGSLHALSWVDMPLYIYGEQGDPPKDYGFRVKATNGKTYYVQVKVLETLELNIGFEWEARIVERRCKFTIDGVEGYGISECMYRHPGGRPLEHSKSDPESIKTKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6C5</accession>
    <name>A0A1D2N6C5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_05863</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Binds to RNA. Required for female germline development, cell viability during eye development and for survival of dividing cells and epithelial cells during early wing disk development.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer. Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000185">
        <property type="protein sequence ID" value="ODN00818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6C5"/>
    <dbReference type="STRING" id="48709.A0A1D2N6C5"/>
    <dbReference type="OMA" id="TPDIDKW"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000011">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000014">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 11" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="124"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="293"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="315"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN00818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="352" mass="40599" checksum="18241A97FF3530F0" modified="2016-11-30" version="1">MSSGDESGDEKKAKGPVDNAWAMKIPEFKKQDNPHGVVEESSFATLFPRYREKYLREAWPLVQKTLSEYNLKAELDVVEGSMTVKTTRQTWDPYIIVKARDMIKLMARSVPYEQAIKVLLDDVGADIIKVGNMVRNRDRFVRRRQRIIGPNGATLKAIELLTNCYVLVQGNTVAAVGPYKGLQQVHRIVEDTMKNIHPIYHVKTLMIKRELAKDPKLKDENWERFLPKFTHKNLSKRKEPKKKKIKKPYTPFPPPMPESKVDKELASGEYFMKEADRKAKKYLEKKEKQIVAAKAREEKRNASFIPPAESPDSSSKAKQDESTNKEVDVEKLKKKVKRLQNKMKKRQTTTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6H3</accession>
    <name>A0A1D2N6H3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-1,3-glucan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6H3"/>
    <dbReference type="STRING" id="48709.A0A1D2N6H3"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="147"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="489" mass="55297" checksum="8135547216246310" modified="2016-11-30" version="1">MSSMIEDRRPFAAAMQNYHLMDVDATESQASLNIPEDNGKKYRAERPQFLGINWRMLCSVISIIFFILTLLLFIGTIVAYYNRPTNDALQANTGDASSNSAPGYTGKDGHSTTTESPPNRNGEGFIDPSKSAEPPETKFETEKWSVTTFNGKRVKPGELILSEEFTTFNESWFHFTGSMDSNFYFHVNNNSTSFVKDGILHLKPVYSEDRFGKAYMENGTLLLGIHPSERCMNGSSVCWKNPGSIVHPIMAPMLMSKNYFKFKYGKLLIKARMPKGDWIEPIISLQPDDPFYGDDLKSGQIHFVDVRGNRKLFNLDGVNVGSEQTCPDIRYGTNANKKVLYYCLNTDEDEGFDRDFHIYELEWTPESITIKIDGEGIVGGPFPRPSMYKLWSKGKSISNPWGLAENPKLAPFDKEFSLVMGVSVGGTNGFFNDEFNNTAYPKPWNNTDEDAAKKFWDARNLWEPSWANDGSSLQIDFIRLYALNETMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9D3</accession>
    <name>A0A1D2N9D3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposable element P transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000136">
        <property type="protein sequence ID" value="ODN01854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9D3"/>
    <dbReference type="OMA" id="FNMINDT"/>
    <dbReference type="OrthoDB" id="8948150at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048366">
        <property type="entry name" value="TNP-like_GBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048365">
        <property type="entry name" value="TNP-like_RNaseH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21788">
        <property type="entry name" value="TNP-like_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21787">
        <property type="entry name" value="TNP-like_RNaseH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposable element P transposase-like RNase H" evidence="1">
        <location>
            <begin position="47"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Transposable element P transposase-like GTP-binding insertion" evidence="2">
        <location>
            <begin position="212"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="496" mass="55757" checksum="5CC7E7B9467B5F37" modified="2016-11-30" version="1">MRYQADWLLQALLLKITSPKCYRKLRASKFGFSPLFLESWNPSSRTNPCDCQVMLMCDEMGVQEGISFEKMTKKFKGYIDYADFTEYAKERKLQNASDHCLTQPIACFATRGAAPGNILAKMLISAIKVGLQVVGFVSDGAATNKSMWRELGIPTNVGSGIVNSITNPVDEGRQVFFLCDIPHILKCIRKTSTIRKTSRFAFAQIQIIFDTIRKMGEQIISWTYYKALYDVDNKSDLRIVPKLTPRDIAPGPFQKMSVASAAHVFSNSTANGLKAYREIGQNNFFQKSEPTENFTRLLNDLFDACNGRIPMDGLRPENAKYKELKIIKEFLAAMSPSDTYASDQTFVSLQVTLTSLLELTHYLCNVIGYHYVLAGKCNQDPLEQINEDHGYSIPHISRCIVYQFSGFLAYKGKAFTKCVDCIESLIDRNPNTHDMRLTAMKDFGGLKYPSQALFNMINDTLEPALHNKLSSPDAVAEFVPSFIENLPNMNAFGCTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB78</accession>
    <name>A0A1D2NB78_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein phosphatase 1 regulatory subunit 35 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04165</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP1R35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000108">
        <property type="protein sequence ID" value="ODN02501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB78"/>
    <dbReference type="OrthoDB" id="10632128at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029135">
        <property type="entry name" value="PPP1R35_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15503">
        <property type="entry name" value="PPP1R35_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein phosphatase 1 regulatory subunit 35 C-terminal" evidence="7">
        <location>
            <begin position="225"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="302"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN02501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="369" mass="41097" checksum="7EE0E9423631272E" modified="2016-11-30" version="1">MSLSSGSSSSGHSYKGGGGMNGIPKVGYFAHHDYPQDDVGGGNENDFRNRYGAIREGGSRVGAISTENGAINLHIPCAFSYAYDVPVPPQNSKKSSESAKGKKSNKDVQHMFQKYPIRKPNSSTVPKQKEQGPFYTSVKSGQLYKAKDVHINSKTHNKTSVVWDFKTGGVPYQAVDYGRELYEQAAQNLAKSLHQQKLEESKSKLDEVEDNCRDYSKPAINSSKKTALALEKAMESLKKLPVEVEELLRKDKRFEPVVMSKATRALNVPRNTKVYKDLIPVDAHPDVQTEAENMIQAEIKRSIEATRQPSRTKDPEPNLQEIQTNSYTRIRPSPVPTPSKPSSGISLDVSHEFDAIENEKQWKDDSNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBD1</accession>
    <name>A0A1D2NBD1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBD1"/>
    <dbReference type="OMA" id="DINCGEY"/>
    <dbReference type="OrthoDB" id="8279338at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="51663" checksum="139C938360B1A86A" modified="2016-11-30" version="1">MMEPFENSVRRGTKWNWWQLDLVLIVILLCSCFPQIGSLSLKPPAEEILNTQLCPNPVIARGFSTPDAGDSTKIMAIGLDQVAKPKDKSYSYFARFTPCTFTEDSDNTLLGAIFGGESNPNATQIRIKSINLSTEPWKFSGSAKCTKFIMFKSRADYGNGYSSVMCGRDNFDEYLGPYGYPMILYYHLKERGIAFPLLHPNYGPNNRDLKETFELKYMLIYYSIKKNGLHTCQLQQYAINPRQQYCSPTDINCGEYDCTELDTLYQKKMGMVRNGDHHQQRFIIVKSKNQEKYRVRNFLRQKFVPIVFLLVLIFAYKSYMKAGLRLNDPLPLQVSEMRLRRYQQRQSHNLHHHHAHNPPPYMSSSGGDQFRDIYFEYGNEHIPGLHIPFEPNPPGITPVDPLQDPDAAQQCPPNNRAKFGHGIGGPPPSYESLFPPTYNEATSSADPKNPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBE7</accession>
    <name>A0A1D2NBE7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_04103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000105">
        <property type="protein sequence ID" value="ODN02573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBE7"/>
    <dbReference type="OrthoDB" id="9922675at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030141">
        <property type="term" value="C:secretory granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007945">
        <property type="entry name" value="Secretogranin_V"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05281">
        <property type="entry name" value="Secretogranin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="95" mass="10440" checksum="FBCF064C44F1427C" modified="2016-11-30" version="1">MFDCPMLSDAEDTELDFSGQQLLSDLQVEGQHKSLVAKKFYNKKSHEDRLSRLNTMAKEAAAAVHESGAKPEDNPFLQGDKLPIAAKKGNHALVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCS3</accession>
    <name>A0A1D2NCS3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Melanoma-associated antigen D2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCS3"/>
    <dbReference type="STRING" id="48709.A0A1D2NCS3"/>
    <dbReference type="OMA" id="CETISKN"/>
    <dbReference type="OrthoDB" id="205198at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="136"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="405" mass="45982" checksum="C813EC929C176BF3" modified="2016-11-30" version="1">MAPARKNTRSAGKSTAVGRKRVMAVESDSDNNSGDGHESPEGDFEIMDTEFQDPGTPPSTARQRKKNTRSADLPEYARSQRSRNLKTNSRKKKDADKDEEGGLFYDFETARELSEKEMRDNIMYYVWMQHASTMRPVRKCDLVKLAINKQTKDYPEAIASAEEELENTFGLKLVGFKNGENDSVVGCTVLEASNFIIVSKFRQLATSNVVPVAQIPSGLVKAGLLTILACAYMMDRSLDEDTIWTIFEHLEFTEHICKKKDDLKRFLKTEYVDTMYLTKCEMKDTDEGVIRYGWGFRAEQEFYKYAVLKYVCETISKNPEDFPTHFSKLSRREVALISGQDEFRNASVDDIDVGDSSDEIDVLDDVYDGSRSQATKKSQTSRKQNRNTIEDEDSSETNGEVEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDC9</accession>
    <name>A0A1D2NDC9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tyrosine-protein phosphatase Lar</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_03685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000090">
        <property type="protein sequence ID" value="ODN02996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDC9"/>
    <dbReference type="STRING" id="48709.A0A1D2NDC9"/>
    <dbReference type="OrthoDB" id="10253954at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000023">
        <property type="entry name" value="receptor-type tyrosine-protein phosphatase delta isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF14">
        <property type="entry name" value="CELL ADHESION MOLECULE DSCAM2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN02996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="183" mass="20323" checksum="A2343C983EE27766" modified="2016-11-30" version="1">MYPPQIVEKLKDQRVKAGSPATFYCRVTGDPPPTIHWRKNGKKQPGGHTRIFIENFPGVSMLRINPARHVRDDASYECMAENGVGDPVTASANLTVFSDQRGGMPAMQCQAADGYTKDITPMNEQPRLAGGASCVVLQHKKSDEDQDSSHLFHCSLSHSNLTQIFFLFFNSHRAEISQSLFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDN9</accession>
    <name>A0A1D2NDN9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein disulfide-isomerase</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_03359</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000077">
        <property type="protein sequence ID" value="ODN03361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDN9"/>
    <dbReference type="STRING" id="48709.A0A1D2NDN9"/>
    <dbReference type="OMA" id="KQKLWGW"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02983">
        <property type="entry name" value="P5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03001">
        <property type="entry name" value="PDI_a_P5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000107">
        <property type="entry name" value="Protein disulfide-isomerase 5-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000032">
        <property type="entry name" value="Protein disulfide-isomerase A6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905409" description="protein disulfide-isomerase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="12"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="125"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="398"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN03361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="435" mass="47389" checksum="DBAB01C4C8F5BEAA" modified="2016-11-30" version="1">MDKWRGLQLIPLLLALCATAQALYSSNSDVISLTSGNFDRLVKESDSVWIVEFFAPWCGHCKSLAPEYEKAAKALKGVVKVGAVDADQDKSLGNQYNIRGFPTIKIISGGKTEDYNGQRTAKGIVEAALKAARDKVDAQMNGRSSGGGSSGGSGSKKDVVELTDSNFQKLVLDSDEPWLVEFFAPWCGHCQRLEPEWAKAATELKGKVKVGALDATAHPGKASEYGVQGYPTIKFFPAGRKRSSDAEDYDGGRTADAIINWANDKATASMPPPELEQILNDDVLQEGCVKHSLCVVSVVPHILDCDAACRNRYLNILRANGEKYKRNQWGWLWAQAGDHLNLEEAIDIGGFGYPAMAVVSAKKGKYSLFRGSFSEEGIREFLRDLSYGKGSTAPIRGATLPKIDSVDPWDGKDGQLPQEESLLDLDDAFDDKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEL9</accession>
    <name>A0A1D2NEL9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEL9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="161"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="311" mass="34687" checksum="E9F65B8EC9DCE6F4" modified="2016-11-30" version="1">MHSSTRHLVDSSQTTDNKSIRGGMSSISVSSSLPTDEIDNHLSQIRYKKTVQDETAENGNSASAVLSSPQVSKVMASLFGSEKMELSTDTRQTLKTMEEFFKELIKATSVNNGSKVKEALNEVFHNPEEIVFQQILCNPPEDWAVSALQLVQDVAKKEALCEEIDGDIKDIKQKRRELAKDAGILKKELEEMKQSHKKKLEKLNPDNIRRLKIALESYKSEADKLEEIRSQNPGASDEDVEKILTDFEALKVRHEKAKNDLHQVSGGGVLPPNIEQARAILAQRKAYLASLQDQIANPDLSSTLDDSVFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEN0</accession>
    <name>A0A1D2NEN0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Swi5-dependent recombination DNA repair protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000065">
        <property type="protein sequence ID" value="ODN03728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEN0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032798">
        <property type="term" value="C:Swi5-Sfr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042429">
        <property type="entry name" value="SFR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28643">
        <property type="entry name" value="SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28643:SF1">
        <property type="entry name" value="SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="20649" checksum="113E41B341C6E8E2" modified="2016-11-30" version="1" fragment="single">IIDGMEEICNTTAEAPGPRKEHLDMHTDSAGGCQTTTDLPSIEISTQNQDTARSTGTNINEDKVDTPSSKRIKLDSNLSEDLKSNEACLVSSDETPTTLDELNKKKKCIKQKKELLEQLELVKLYQNKWSIQELTDLTTSWKDVATSAFEDLHQLCSVGETLTKKGLIKHLGIDGSLIDIDSDPDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFC5</accession>
    <name>A0A1D2NFC5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translocon-associated protein subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Signal sequence receptor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_02707</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAP-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFC5"/>
    <dbReference type="STRING" id="48709.A0A1D2NFC5"/>
    <dbReference type="OMA" id="QCSNNPK"/>
    <dbReference type="OrthoDB" id="10055808at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008855">
        <property type="entry name" value="TRAP-delta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12731:SF1">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12731">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05404">
        <property type="entry name" value="TRAP-delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0832">Ubl conjugation</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905479" description="Translocon-associated protein subunit delta" evidence="15">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN03951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="166" mass="17574" checksum="ECE18B7EE3BBB765" modified="2016-11-30" version="1">MKGFLVVFAVLTASSVALASNCQVSNQRTYTTQDASVLTSIAYITEFELTCDGKKVVGTQLYAESQGSILQVGENNGNYQVSWVEDLALATKGDHPLRIVDDEGVSVVRKAQKTGASIDGVKPLASLILNHPGAYTGPWLSSEHLAAIMGVVVVYVAVTSKSKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFW1</accession>
    <name>A0A1D2NFW1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heparan-alpha-glucosaminide N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFW1"/>
    <dbReference type="STRING" id="48709.A0A1D2NFW1"/>
    <dbReference type="OMA" id="CHQCLYQ"/>
    <dbReference type="OrthoDB" id="2149840at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31061">
        <property type="entry name" value="LD22376P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31061:SF24">
        <property type="entry name" value="LD22376P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Heparan-alpha-glucosaminide N-acetyltransferase catalytic" evidence="2">
        <location>
            <begin position="202"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="596" mass="66601" checksum="86E42F27049153AB" modified="2016-11-30" version="1">MSWTESHGFSTFGQYNLTLLGVDQAWLNITNNLENQTLWLYELSKDCLGCPHVINHDVAAVKAGASKEIIVSTKFPLNYRLERDGATEIIRENENGGFIRNLHCQVDTSMGEFGIYELNAQEDGCEFVTVLKPVSIFLPFLIPFFFYLGLAAVIFILKKYKTQIFRAVGLGKKSNETDAVLAVSSVRTIDKPTAPAPPASKRLSALDTFRGISIVVMMFVHDGRAGYYFLDHATWDGLFVADLVFPWFLWIMGVCIPVSIKSQVKRDTPKLTILKRIIIRSIKLIAIGIMLNSKGGPIEFATLRLPGVLQRFGICYFVTATCVLICADKGCSNNNKPQNKYLAMVQDILIIWKGWVIVLACVVLHTCLTFFLKVPGCPTGYLGPGGLHDGAKYPGECVGGASGYIDRQILTMNHIYQWPTAKGTYRSIAYDPEGLLGTLTSILTVWLGVQVGLILQVYPKHKSRLIRWAIWAVVLGAIGAALCGAKQTGGAIPLNKNLWSLSFVLVLSSFALILLMVLYVTIDMLKIWSGTPFREPGMNSILLYVAHLVMNDMLPFHFRLKTMNTHFKLLAESLWSISLWVIYAIYLFHKKFFWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGJ2</accession>
    <name>A0A1D2NGJ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000046">
        <property type="protein sequence ID" value="ODN04380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGJ2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905523" evidence="1">
        <location>
            <begin position="20"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="57" mass="6383" checksum="B385C64616565B4B" modified="2016-11-30" version="1">MSQLFALLVLMAVMAVASAHTIMAVMALPSLRWPWIQLSGYGSYGGYYGRSWIWCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHH2</accession>
    <name>A0A1D2NHH2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Spondin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02278</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000044">
        <property type="protein sequence ID" value="ODN04416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHH2"/>
    <dbReference type="STRING" id="48709.A0A1D2NHH2"/>
    <dbReference type="OMA" id="PKSFPKY"/>
    <dbReference type="OrthoDB" id="6090599at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.100.10:FF:000134">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2130">
        <property type="entry name" value="F-spondin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051418">
        <property type="entry name" value="Spondin/Thrombospondin_T1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009465">
        <property type="entry name" value="Spondin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038678">
        <property type="entry name" value="Spondin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044004">
        <property type="entry name" value="TSP1_spondin_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038123">
        <property type="entry name" value="NF038123_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11311">
        <property type="entry name" value="SPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11311:SF15">
        <property type="entry name" value="SPONDIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06468">
        <property type="entry name" value="Spond_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19028">
        <property type="entry name" value="TSP1_spondin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51020">
        <property type="entry name" value="SPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Spondin" evidence="10">
        <location>
            <begin position="31"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="387" mass="43450" checksum="0B980CC983DE9B47" modified="2016-11-30" version="1">MVSSVTKLLRPLWITGFVTIVAINSLLITQVESQCSPERLVVYNVIMKTHWSRELFPKQYPEFRPPAQWSKLVGRTHNTSFSLYRIGGMASQGLKRFAETSSSDVLDETAQGSTGVLDAFNGSPIGTGVGLTETQFFVDGNHTMVSLLSRIVPSPDWFVGIDSLNLCMDQQWIDNIAVDVEPIDAGTDSGFTFTAPNWVTVPQEAIYQIHLTTLHPAHSFQYPDNRLRDKPIATFIIYKMKEYSLSQWGASRISDEGSSSSSYGSSTSNSSDPPYHHLFSDDIDSNDIGNELNEINDPKDVEDMSLRLSKKKRARKIKGPLSRTARDCKVSDWSEWSECSALCGFGEQYRHRYVISHSRNGGSLCPSLTDKRLCNSARDCRQNYFDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIC3</accession>
    <name>A0A1D2NIC3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Survival motor neuron protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000031">
        <property type="protein sequence ID" value="ODN05007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIC3"/>
    <dbReference type="OrthoDB" id="197400at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22852">
        <property type="entry name" value="SMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047313">
        <property type="entry name" value="SMN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049481">
        <property type="entry name" value="SMN_G2-BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20636">
        <property type="entry name" value="SMN_G2-BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival Motor Neuron Gemin2-binding" evidence="2">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="24440" checksum="46872E33A2024837" modified="2016-11-30" version="1">MATSHNSASLMESEDAWDDRELIRAYDKAVKNWRRNRDTDAATKSETETPGPGPWVEVPGRAANSGSRNLSNDRVVERNLKIAEFQTHLSHPITQPVSVEGGFPYSAEATVDSSSEISSVEEEPEEVEDVQDYTSVEGESSYPQYRFPVPPMPLSFSKKDGSFDFGRGELPALLMSWYMAGYQAGFYDAKQEFKSGKRSDTKKAPEMSSAAHVKSQKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIH9</accession>
    <name>A0A1D2NIH9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000034">
        <property type="protein sequence ID" value="ODN04895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIH9"/>
    <dbReference type="OMA" id="RREWANA"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="393"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="619" mass="71729" checksum="2E27CF5E9A68D48C" modified="2016-11-30" version="1">MNSLNSINGIGVVSTPITKKRTVTNLEEKALVRLGEPRPRPRKPLTKFTTTSPNPNLSDSHLIPAYRTTARESLPIVTKEEKKKLNISPTTGVLENSSSLRARHRLLKRKTIHSSLEDLRYTKNLSCESRKSIPLPSRDTHQYQVRYHDGSRSVTRVPASGNSQRVNENLLWRHSTVQTDAIIDADKDGGSGDKRNSFIDDDDNISNQNTFQSSRNIAQNNVEEEDNLANLSAENDLLKRKIEKERRKSIFYQIISTFVFTALRARSQRLDEIDELVQQKRVECAARMILHHLLLNSWKMTKGQVAAISTENAQLHKTIDNQSLQLTIVRKMQSMEKEKTSTVFKEYEKIKRNYGGTIKENETLKEEYSNVLEEKSSLEWSLKSLSDENTRLNTDLRIRLEKKEMQVRSMELDRMRAEKFSRENEDLAKEANISKSQIKELASQKKHWQEKAMEWESKCYEQQLEMENREKAYEKLLDEKKEVSKENEILALSKSKLEKAVDEAKVKLEESTTERKALQLSCNECKDQLEDLEDQVQYLQSTLRRYKRENAEIRQKLYDCTLKNVHKRRVWGAALYFIVSPFEAFKRFYFGTPEQSRERSSCGRSCSGMLDSDSKSSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIZ1</accession>
    <name>A0A1D2NIZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIZ1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="83" mass="9556" checksum="9E8ABCFC00BDF261" modified="2016-11-30" version="1">MMNKTEKKKKISRKVYMQLHTKKIFWLSSFASLNVSSPPVKSGLLRQEARTERNAASAKALARRLPTRNKVSLQLWRSAVKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ70</accession>
    <name>A0A1D2NJ70_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Y-box factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_01346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NJ70"/>
    <dbReference type="OrthoDB" id="203339at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050181">
        <property type="entry name" value="Cold_shock_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11544">
        <property type="entry name" value="COLD SHOCK DOMAIN CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="72"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1476"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1141"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1476"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1539"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1571"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1592"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1608"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1626"/>
            <end position="1652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN05310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1830" mass="202694" checksum="4220503EE3608D0F" modified="2016-11-30" version="1">MRVAGQWGTVLPKTDARRPADQVENFPSPSPTNMADTETKQTSEQQPTAQQQSQPSQQQKPVPKDKEIIATKVTGIVKWFNVKSGYGFINRSDTKEDVFVHQSAIVKNNPRKLVRSVGDGEEVEFDVVVGEKGNEAANVTGLAGEPVKGSPYAADRRRGGYYRRSRADVVATAVMVAQEGHAETNREVKATREKSRKVKKRKKISSNHRSVVKEDEVVAVDSVAMKAEDAIVTIVVGEDEGARALTPKVKTQEREVKVSQRTNNKKVVTTSAVVDPEVVVGGVADEDGGDSLVDSIAGELHVDVHQTAEKRGVKAGKKARRSPMRVLRQRIPPPPQNFLNNLNNPPQQPLPPQQQQNISSGLNIQLIQQQQQNDELANIKDENIKRVLLELSTLQTPSQMSETMARVAQLVGPLFISNFDDRKDQIVAQGRDASSFPQRLLSAVTDIQGEEVKALVLQKRLELLHAGDFAFLPLAIQYGLQDEILRNLSGTKLASVVKANPGDTVIAFKVSTALKDRSDQQLEFLQSLGTKLLPEVQRIIMRQLLQWWGDPHNWKDRELTLLTSAGNPLLAFMPQSDLESLDDELADRFVTILGQTQDIGRGWWRKPMSLKKAWFELAKGARYFGAVHEWSFRRMQKLSFLLEGASPEDLELIPPVPEIKSLVIGNHYTELQARIVFDAFYHTAPLSQEDLQEFQFHLLDLTPSQVQRFDFADSFGTLDEMMSILERQTQPAYPTILQISYFMWPIVNSTNSAMSIAPPAIWQKRELSQIGKMFFLLPKSILMQMKPDIINWDSNILASIRSNHLSTFQVWRLTAQILQTVDERFRPDYIFMIPSPFQKGIPTQNISQALLGTTSVRPEILRALIEETSGMLTSQKAVILQRIINRISEAIVIRTMISTQDPSEMFNLISPKVLNKNMATIIKTIMEMPETGRFGITSVQTKLLPHITLSLWLKWVRENAQVTRWTAEDLLGRSPMGATHELDLAILGLSCRDIDIVDSWDVLSVIMHYRHELYGLRRFKPTLTFNVNLRLCVLLKFVEYLKQKRFLNGDQADGHVLSEVTMGEIEAVGGEILSLVPTQALDQLQIETRQNIIKEIGQLQMLELFSLIPLQDLHWYGTTLFRDIAIMSGAPNTPRNRRQTDSTPIAATTTTDATNSTSPDPGIDGGGNSTDTQTPVSTATTTTTSSIPATPSSTPKGVDLEALNKMGNLICYADNLFDSNWPRNLLKDVLEAKTSVGEKTCCLTKILREKWFEALKNAYGSDTSSWNEFDLSAIGDLLIALPEQDLQKISLDSLGKAVTPMMRQSAFDIKIAIPGHVKRIQFATACTDALGTEGLEFNSAFKKLMKRIFQASQWNVNTVKTTQELIRDGVGRTGRIPRWAEHTLVKRQVPISVGGELAYTGSGYTPATVSSPIISATPSSSYYPAVTGGDAYSNNQNARQSMYTASPASYSSQQQVTNIQPIASYSPQQSNVGYGNQGVINQLSPQTTSSMPAQSGTGYAQSTPAFSSPQQNFNPMQSSTSYSPQYTAQPAAQSVNAFSPQSLSNSPQQQLPATASQYSPQYSPVYSSPQTQAIGNNLGQGYAPQSNTGYGSPASSLTSPQSSQPNSGSVREQQSNILDCHKEQQNHAGGSQSPTIGPNQVPASSRPTKQQVKLNTSSIQISYIISEHRAYLTTQQAKRDYLSGFCCPLDRQCRIHTVVTENRKKLRGRSAASVGRKKLDDVLVNSIYLWTLTSDLFDCVEALGNIEWDDETKGQILSLLKQKLEFNKDSINALTLIEMGDLVTAFNTKSQGSSVSDGFSSTNITESSLKTYTKIHPINVIGESKMKILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ81</accession>
    <name>A0A1D2NJ81_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Homeobox protein AKR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_01356</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TALE/TGIF homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000025">
        <property type="protein sequence ID" value="ODN05297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ81"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ81"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001654">
        <property type="term" value="P:eye development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000059">
        <property type="entry name" value="TGFB-induced factor homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 8 11" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="39"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="8">
        <location>
            <begin position="41"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN05297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="320" mass="35546" checksum="F7D9D2F8F22A71C3" modified="2016-11-30" version="1">MCYSSDADIPMTSDLGTGVQGMSASDDNDHKSLSPSKEPLERKKRGTLPKESVTLLTQWLYDHRYNAYPSESEKIELSKQAKLSLLQVCNWFINARRRILPEMILSEGQDPQQFTISRRTTNRRRHHFQIQGSNSSKTSSSSSSSSNNAAPPKQHSSNDGLSSDSSSSSSDDHHYQYRHKKRRILQAYAASKGDSSSGESLPTHPFILDSKPSITSSKVKVTSLSPLTDLKKESQPTSATTTTTVNMAVNIVKHENNNSIGNNTKTKTPTTPLLRTPMESTTHSHFLSKLLFKCESSSFKCSRPLQTPPLLLPLKPPQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKD8</accession>
    <name>A0A1D2NKD8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purple acid phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000017">
        <property type="protein sequence ID" value="ODN05730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKD8"/>
    <dbReference type="STRING" id="48709.A0A1D2NKD8"/>
    <dbReference type="OMA" id="CKDVFEP"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811381" description="Purple acid phosphatase" evidence="3">
        <location>
            <begin position="23"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="6">
        <location>
            <begin position="60"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="163"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="5">
        <location>
            <begin position="392"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="479" mass="55376" checksum="348F07C0F3D862A9" modified="2016-11-30" version="1">MTLASTLAKFLVILLSVYNVRASLVLDNLSDPLYAQAEPDAETGYETNVIFEAGLHYYQPRHVHISYGNSPTEMFVTWSTLSDPGSSIVEFGRGKLSDYRVNGSTTTFTDSGPYKLTQFIHRVTLENLEPGQPYMYHVGSDLGWSEIFFFRVMPNDTNWLPQVAVFGDLGSENAQSLTRLQEEVQMGMYDAIIHVGDFAYDMNTDNGLVGDSFMDQIQPIAGYVPYMTCPGNHENADNFAQYKNRFTMPGDTESMYFSFNMGPIHFISFSTEFYYFLNYGMSPLINQYYWLENDLKEATKPENRAIRPWIVTFGHRPMYCSNNNTDDCTYHETRVRVGVPFLHWFGLEDMFMQYGVDLTIWAHEHSYERMFPLYNRTVYNGSLEEPYRNPKALVHVTTGSAGCKERHDDFLDYMPRWTAFRSTDYGYSRLKVINNTHLYVEQVSDDKDGKVIDSFTLIRDHHEPYDIPIPPEPELDLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLK0</accession>
    <name>A0A1D2NLK0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLK0"/>
    <dbReference type="STRING" id="48709.A0A1D2NLK0"/>
    <dbReference type="OMA" id="VANHYLH"/>
    <dbReference type="OrthoDB" id="154356at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990841">
        <property type="term" value="F:promoter-specific chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07982">
        <property type="entry name" value="HFD_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003923">
        <property type="entry name" value="TAF10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03540">
        <property type="entry name" value="TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01443">
        <property type="entry name" value="TFIID30KDSUB"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN06117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="218" mass="22987" checksum="24DD9ECCF3EE3FBB" modified="2016-11-30" version="1">MDSFNASPAKAGDAMDISAPSTPSFSAPGSVASMPGTPLVFTPNISTNVSSPIAARIGMGNDGEVKVDMPPAPTPTFQFQRTPSPLGAGASGASSSSFNSYSNSSQDSSDSTGFALSDLLMQLEDYSPTIPDAVANHYLHMAGFESSDPRMSRLLSLAAQKFISDIVNEAFQQCKLKGQVVTAGKAKVKDKKYVLTMEDLIPVLNEHGIAIRKPPYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLZ6</accession>
    <name>A0A1D2NLZ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Basement membrane-specific heparan sulfate proteoglycan core protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000008">
        <property type="protein sequence ID" value="ODN06257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLZ6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="279" mass="31368" checksum="3AE4D274FC1B7DF2" modified="2016-11-30" version="1">MTKSENDLVFEEDHETSRNLIITGKSSSPHKRGKTNSSDKVIDKNKRFKWEPNDDPGDGVGRLSQPSHRRPSSSSKIPKELSVGLASPYRLTNEGRKRATRVSETDDEDLINSGDELGSGERPATEYSPSVGGTGGPGPGRGDESTSFEKRYYRIALTIGKSWSPSLETRSSSAFAVYQHELEREIRQVMSLEAEHIQIVNFQNINDPAFVRCVFDLGVVGTPTEQVEEEFLTYLDVGSIGQLRIRRDGFSVRDIGGKKREFSWQRKWMDVSYYVELTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM76</accession>
    <name>A0A1D2NM76_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="8">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00351</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the endoplasmic reticulum-associated degradation (ERAD) pathway that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. May initiate ERAD by promoting the first mannose trimming step of ERAD substrates, from Man9GlcNAc2 to Man8GlcNAc2. Seems to recognize and bind to exposed hydrophobic regions in target proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM76"/>
    <dbReference type="STRING" id="48709.A0A1D2NM76"/>
    <dbReference type="OMA" id="GKCTVYA"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904154">
        <property type="term" value="P:positive regulation of retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000015">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF6">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905756" description="alpha-1,2-Mannosidase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="627"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="681"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="687"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="828" mass="93826" checksum="42D3700D1967205C" modified="2016-11-30" version="1">MPSWTLILGFLWLLTTVTLNSISAVRTYDAKRMTELREEVRSMFYHAYDSYIRHAYPYDELRPLTCDGVDTWGSYSLTLIDTLDTLAVMGNYSEFRRVAKLIIDNAHFDLNINVSVFETNIRIIGGLLSAHLLSHKAGMEVEKGWPCNGPLLRLAEKVARKLLPAFDTKTGMPYGTVNLRYGVPPSETPITCTAGVGTFIVEFGALSRLTGDPLYEKVKKSCLDWLKVVALRAIHSLYAKRSSIDLFGNHIDTSSGKWTAVDSGIGAGVDSFFEYLVKGGILFQRPELMHMFRVSYRAIEKHLGKGGWYIWATMNQGHVSTPAFSSLETYWPGLLSLIGEFKTALKSITNYHRILKQYGGIPELYNILQGKASHQREGYPLRPELIESAMYLYRATEDPQMLEIGEDFLHSIEHTARTECGYATIRDVTTMTLEDRMESFFLAETIKYLYLLFDPDNFIHSDGTDYTVVDSPVGKCTVYAGGYIFNTEAHPIDPSALHCCTGVREQELHDEIQHIDEVPFSRKFTGLSNKKKEQGRRKRKKGAKKQNLEMELTNLESDDEDIIQLNHGIEIELQSMSNRGSCHAKDFATEMRTLPRKQPPSVLKEPESPDEESMLDRLLRRLFEEHSSEAQKEDKAATVEDKNRISSPDTQKKGLKFVTLDEAERLQKMVQSFESNVKALKDKRTAEQSLKQQSTSPKNTENRIRTASTSTLTGGGGGGGTSPKVEKYSGPDLDLIFGTGTSSRSLSFYFSLKWLKAFPDLIKQLIPAEKFDIQAFYSRMSDNEQFSDETYAKDFNFTVGWSRDYQALRCPRIGIPERFMFLRPSIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMK6</accession>
    <name>A0A1D2NMK6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDZ and LIM domain protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMK6"/>
    <dbReference type="OrthoDB" id="44841at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="227" mass="24071" checksum="F260F0B69B795255" modified="2016-11-30" version="1">MKIERLEKDKTADLAGLKIGDLIIGVNGEDVTTVPNTAIYNKMKSTGMELHLEIWRKHPHVASPLPPHMTSANIPHPVHPAALIQPPPTHPPGTISSLPPSNNKPVVANPSSTDYRDQRPTAHNSTTTALPQNSSYNCNGIKNTTPGLPNTTAAAPGGLVAVHNPLLNRITPQPPPPTSILKPPPPAPPVSSSNLGNSCPSQSQQPTTASSSWRIRFNIEVGQGTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMR3</accession>
    <name>A0A1D2NMR3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GTP:AMP phosphotransferase, mitochondrial</fullName>
            <ecNumber evidence="7">2.7.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Adenylate kinase 3</fullName>
            <shortName evidence="7">AK 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_00135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:13749"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylate kinase family. AK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.10" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMR3"/>
    <dbReference type="STRING" id="48709.A0A1D2NMR3"/>
    <dbReference type="OMA" id="IVKDEYC"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046899">
        <property type="term" value="F:nucleoside triphosphate adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006172">
        <property type="term" value="P:ADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046039">
        <property type="term" value="P:GTP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046041">
        <property type="term" value="P:ITP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000106">
        <property type="entry name" value="Adenylate kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03169">
        <property type="entry name" value="Adenylate_kinase_AK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036193">
        <property type="entry name" value="ADK_active_lid_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028586">
        <property type="entry name" value="AK3/Ak4_mitochondrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57774">
        <property type="entry name" value="Microbial and mitochondrial ADK, insert 'zinc finger' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="10">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="7">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="7">
        <location>
            <begin position="163"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="51"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN06554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="259" mass="28690" checksum="602E9609C2F10CAF" modified="2016-11-30" version="1">MLSKPVRQVIGLSGGAKMIVMSSLQGFKRAFSVTARNDRKKIHGIIFGAPGSGKGTISERIVKIFELKHLSSGDLLRAHINQKTEFGAKIAPIVNSGGLVGTELLAPLIDHELKLADSNKCGWLLDGYPRTVDQAALLDKSVAPNAVIYLNVPFATIIDRIKARWVHAPSGRVYNLDYNPPKTPGKDDQTGEPLTQREDDKPESVRKRLELYQKVADPVLDFYRSKNILREFKGTESNVIFPVVQAYLENYFIFVSANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0P5</accession>
    <name>A0A1D2M0P5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_20146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008376">
        <property type="protein sequence ID" value="ODM86536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0P5"/>
    <dbReference type="OMA" id="IFGTHFT"/>
    <dbReference type="OrthoDB" id="6755924at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="10340" checksum="828545949159DE7B" modified="2016-11-30" version="1" fragment="single">YLQRTSAIRKSQHLFIQSVAPFEKASSQTISKWASEMLKLAGINTNMFTAHSYRHAATSKAAGLGVSLDSIYKAAGWTNRSNVFRKFLQPSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M213</accession>
    <name>A0A1D2M213_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006511">
        <property type="protein sequence ID" value="ODM86994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M213"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="448" mass="50100" checksum="8CC4877A0C145837" modified="2016-11-30" version="1">MSANKRLKTDLPTSELRMESQTSPKTTVSSRLYTLVPGTQKDSICSIYPILPNVGCSLVKETLKFDSSKEVCYHFALTKEKPGVGGSSLGFKSNVSSDTTSLKVLAADTKSKQMVSALCFSPERLAEDIMGLNHVATFLASIRTGDGIRIQMRLNPGVTSNFAAEASLESPNIARYIVYHGAIDKTDPQWCSELAEFLWYASGGNLPTVQIKGNRVFTSGPKGFELYPQSVLTPFSLLDKEGNKHACHKECWKVNFFINLRLLVILGSCTTVDLLLQHLYHPLEPIPPITTFEVAFETMKLAQQLELTKLLATAVKSLVGKLDLVVKSTVLRELYVFIRQLKFKIQIFAKLWKVLLPKIKSQILEEDGGGNGSFDREASFLNFKSFTKDGYFLFEVMEELCQDLMKGYDFANLEEVAQQLKIQMVINRFKGDVIRRMGFKLAMGKIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2A9</accession>
    <name>A0A1D2M2A9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450 2J5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_19582</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006157">
        <property type="protein sequence ID" value="ODM87100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2A9"/>
    <dbReference type="STRING" id="48709.A0A1D2M2A9"/>
    <dbReference type="OMA" id="AFCVGDM"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM87100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="441" mass="50955" checksum="5D547364058715D0" modified="2016-11-30" version="1">MACPKGLPLIGNVLQLGKFPNDTFTKWSKEYGPIYKVQLGSHIAVIVSDPKLSKEIFTNDPAFAGRPHFDVTNLYEENPRLGMFVSEGDLWEIHRNFLIRQLRTFGFGKSSMEALIMEDVNEVLDKLKKEEGKPIGNIRGMLRLAIVNALWTILSSQRFKHDDPKLGQLTRFSRGSGYNAARRVLEGWKTFLEGTVKEHKEQFHEGNLKDFIDVYLAEVRKTTDEKSYFYGQLGERQLVSTMLNLFIAGSDTSATTLSWTLVYLCKFPHVQKKLQEEIESVTGNERQVSVDDRPMMPYAQALVDEILRYSSIVPDGAQHRATEEREFQGYRIPKDAWIQPNLYYIHHDPRFGRSTEFSAERFLSENGEKYMKNENLQPFQIGRRICVGENLARDNIFLFMTNIFQKFEVRFDPKSKEPGLGTLMGFFRNPEDYSVIMKDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2I6</accession>
    <name>A0A1D2M2I6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingosine-1-phosphate phosphatase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006035">
        <property type="protein sequence ID" value="ODM87152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2I6"/>
    <dbReference type="STRING" id="48709.A0A1D2M2I6"/>
    <dbReference type="OrthoDB" id="301434at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="233" mass="26268" checksum="0D909BF17814CAA6" modified="2016-11-30" version="1" fragment="single">MSHAETHAIVRAAVTLPIVIFTSSRYQKKRVDLVCLSRLYLGMHSMLNIPLGLGLVASLLPKVIPLADKLDSFFPTYEMGGVYLIGLGFFLCLSYPSSDRWTPARHLCHRQKRCRDEPRGLDKVPNGDPPWTSPFQPALRRDVAHLRDDLVGCNPTVFGSWSGAPFQNDGEKTRPFGSNEGLQKELDDDEGRSLAWHTLVGLSATYASPNWRGWEFRDLRSIQKPNRNRNQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2J0</accession>
    <name>A0A1D2M2J0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">beta-ketoacyl-[acyl-carrier-protein] synthase I</fullName>
            <ecNumber evidence="1">2.3.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_19517</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01006018">
        <property type="protein sequence ID" value="ODM87164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2J0"/>
    <dbReference type="STRING" id="48709.A0A1D2M2J0"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Beta-ketoacyl synthase C-terminal" evidence="3">
        <location>
            <begin position="113"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM87164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="176" mass="19361" checksum="A4A032D55E8DD24B" modified="2016-11-30" version="1">MGMLDLQDIQDTGSILDEKGYSRVSPLFHPKSSAKPCCWSDKHQYGLQELSHPLTIINSCFCVSERCPPNLTTSQNSLLDRLTRMGWVVMGEGAGILVLEELNSALKRGAPIYGEILGYGMSGDGHHLTAAREDGRGALRAMEIALKDAGLTTEESLLCKLSRNFNPNRDKQKLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3P2</accession>
    <name>A0A1D2M3P2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Syntaxin-8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_19084</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004996">
        <property type="protein sequence ID" value="ODM87597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3P2"/>
    <dbReference type="STRING" id="48709.A0A1D2M3P2"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd15852">
        <property type="entry name" value="SNARE_Syntaxin8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000036">
        <property type="entry name" value="Putative Syntaxin-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041875">
        <property type="entry name" value="Syntaxin-8_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="14">
        <location>
            <begin position="53"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00072662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM87597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="15948" checksum="66E2A1899A4B6C22" modified="2016-11-30" version="1">MRSLTSGGYAPLGNQPKVVSWDDDDDEDEEVQFSGRGSSDQHASVQQIRQQQAEMLQEQDRGLEALSEVISRQKNLAQVIGNEVEYQNELIDDITDHVDRTNDRLIAQTSRVRTIDRKDATGRYWAVIILLLVVIIIIVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4J0</accession>
    <name>A0A1D2M4J0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Osteopetrosis-associated transmembrane protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004637">
        <property type="protein sequence ID" value="ODM87821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4J0"/>
    <dbReference type="STRING" id="48709.A0A1D2M4J0"/>
    <dbReference type="OrthoDB" id="8021850at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019172">
        <property type="entry name" value="Osteopetrosis-assoc_TM_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15644">
        <property type="entry name" value="OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15644:SF2">
        <property type="entry name" value="OSTEOPETROSIS-ASSOCIATED TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09777">
        <property type="entry name" value="OSTMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM87821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="100" mass="11643" checksum="46BC08577FEDAE2F" modified="2016-11-30" version="1">MQPYYDQMNNKYMEIGELYGENVCVDVLDTMNITRELWSELFQCVPERKAEFWLHIGFGIVATIPLIFYFLAYALSTKQEARVLQQHRLAEVFANTSAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4L4</accession>
    <name>A0A1D2M4L4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oxygen-dependent choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18765</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004416">
        <property type="protein sequence ID" value="ODM87920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4L4"/>
    <dbReference type="STRING" id="48709.A0A1D2M4L4"/>
    <dbReference type="OMA" id="YLRCHIR"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.450.10">
        <property type="entry name" value="Glucose Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027424">
        <property type="entry name" value="Glucose_Oxidase_domain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="44"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="8">
        <location>
            <begin position="410"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="103"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM87920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="503" mass="56356" checksum="F1C8C63FD0890805" modified="2016-11-30" version="1" fragment="single">CGVCPSGQFPFLFNSNASKYLDEDRINTLNELEKDLSLPRIKEYDFIVVGAGTAGCIIARRLSEKFNVLLLEAGGEPVPASQDTDGVIISHLGKNAGGSGSHNDMVHNRGSPKDYDNYAEVANDSSWRYENVLEHFKKYENFIGELFTGEHEENYGHDGPITIDTDTPPSFQFFDVANELGYKVADPNGFQTESFAPMAKAINKGQRSSSYNQYIKPIKNSRENLTIHGYSIATQASVRRFLLMKNKKAYGIVYERHGIPQIAHASKEEAGISVIHELPEVGNNLVDHLIFDLNKIQYNASIIPYIPRMTEEQEFEEMLQNYHETGEGILGHLNQGPQAFIISSRAKQDGQEGWPDILIIYVPMCPFPKGMSLQLPEKVVRMLMWFWKPLTWRFDIINATVMQKYGTFYGDEPHSACLSFEFLSKDYWRCVITQTIHSGYHGVGTCSLGSVVDSKFRVQGISYLRVADASVFPAVPNANINGPVLMLAEKAASDILQILEVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Y9</accession>
    <name>A0A1D2M4Y9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock 70 kDa protein cognate 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18644</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004207">
        <property type="protein sequence ID" value="ODM88036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Y9"/>
    <dbReference type="STRING" id="48709.A0A1D2M4Y9"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24028">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000046">
        <property type="entry name" value="Chaperone protein HscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000005">
        <property type="entry name" value="Heat shock protein ssb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM88036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1087" mass="124043" checksum="78BBAEDE60C06165" modified="2016-11-30" version="1" fragment="single">SSEETISEDFIVETTCATFHTNIVNKAVEKYHDIFKKQSKGLNIQLHDDLQTIHETCVKHANLYFKQAKKLPGYAQKYEEKLKEELEQILKKKLEETFKCRKDFVDNCFKKASENFQTSLENLTDFGSKEIKKLKEEITLEFLGNFLSEDEDNFEMADSLQTAFADTFETFLKQKSIREKELIEQPMREMKQKLIQQYKTRMAEMLENTPTCDSATFHKFHTHILNTIMETFTQAAVGNNFDTAVQPGIEDSSQRLYDEMIENISAILEEFEEAQKYIEVETNAYSNVIMQPCGDQDSLTFHQNEVSSILGKFEENCKFPVDSKEREYFKLKLETSLEEVYYSNKAKNWIHEGLKEYQQQMKRSANSCRSSTDFQKAHEKVKKTIFDSFRKTLQDNCSEHFCREQEKQLGIELESAFEEMEDIFKMKMNADQVSAEELKEETRKFYHNAMRKHVKPRTYMNPVDLQDLHKTTVEAAIEQSKAKPALKKMLENWLQSSFQKYKDENDMVLNYEDGVEPAIGIDLGTTYCCVAVLINGKVEIVRNLQGQNTTPSYVRIDKQSNEQVVGFVAKESSHRYAENTIFDAKRMIGRRFEDEKLQNDMNYWPFSVVQGEEGPAIEVAGNQYPPEQIASFLLRQLVTDAEKFLGKTVTKVVITVPAYFTDGQRQATIDAGEMAGLQVLTILNEPTAASIAYKMERFHEDARNVLIFDLGGGTFDVAILKTDAGSIEILAVDGDTHLGGEDFDKAMMQYCAEKFQNEHKLNPFNGKDSTLKVERDKAKQRLRRLQTYCEKRKIDLSFARSTTISVDTFQGATDLEVTISRETFEELVAPYFTKALQIVERVLKAAKLSKESIEDVVLVGGSTRIPRIQEMLTQFFNGKALNHTINPDEAVAYGAAVKAALMNGNQAKKMFNFKSIQDATPMSLGVEAFVHGVAGHFSAIIPKSSKIPTVVKQKYSTLLDNQDSVLIKIYQGEAHLAKDNEFLGEFILKGIPPAPAGKEMVEVSMHINDMGILHVRAICKSSRGSELLTVFENKGRLSQGTKVRLLKEAQANDPGVLRRSYRRFLSEKGTENHGGFYKPKTVRKSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M590</accession>
    <name>A0A1D2M590_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="5">dUTPase</shortName>
            <ecNumber evidence="5">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18532</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 5">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01004034">
        <property type="protein sequence ID" value="ODM88149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M590"/>
    <dbReference type="STRING" id="48709.A0A1D2M590"/>
    <dbReference type="OMA" id="ETYVTHE"/>
    <dbReference type="OrthoDB" id="419889at2759"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241:SF0">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase-like" evidence="6">
        <location>
            <begin position="27"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="17098" checksum="5DE940286C143EF6" modified="2016-11-30" version="1">MSGFFPLTLIVYFSTDTTIFFITTEENATVPRKCSPQAAGFDLFCVEPEKISAGSITTVDTKIKVLLPRGTYGRIASRSSLCLNGLFVQGGVIDRDFQGTIKVIFYNSSKDDYYFSPGERIAQLILEKIAEAEVQIMHGIWTDTARGEGGFGSTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5H1</accession>
    <name>A0A1D2M5H1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone H3 type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_18464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003952">
        <property type="protein sequence ID" value="ODM88218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5H1"/>
    <dbReference type="STRING" id="48709.A0A1D2M5H1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000085">
        <property type="entry name" value="Histone H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="8">
        <location>
            <begin position="64"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM88218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="183" mass="20690" checksum="6C8DC4123C92DCE1" modified="2016-11-30" version="1">MVRVKQTAQKSTCGKTRVLDTTILAKKQGSKTPRPAKIVCRSGVMKPHRYRPGVVALRESGDTKTTSAHSKTPFQRLVREIAAAFWGHEFRFQAVTFEAFQVATEAYITEVFQDTNLCARHASRVTIMPKDMQHACRIRGGCILNKAFINKTEKSMCLSDKVIGCYCRKLLIANVTFFNLHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5W6</accession>
    <name>A0A1D2M5W6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ectonucleotide pyrophosphatase/phosphodiesterase family member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003786">
        <property type="protein sequence ID" value="ODM88311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5W6"/>
    <dbReference type="STRING" id="48709.A0A1D2M5W6"/>
    <dbReference type="OMA" id="GDHMLYP"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="325" mass="37339" checksum="2A44EBF199E40386" modified="2016-11-30" version="1" fragment="single">MTILNKVHTPTLNELKKRGVSVPYMEPVFPTKTFPNHQSIATGLYAESHGIVGNTFFDPKYNKTLNVNDYEFWNYSPDVLPIWVSLSFEMKWPVEARQADALCWPGSNQPYGSKNDLLPTYYYPTYNASVSWEDRVDIVVSWITNQTKPANLVFLYFEEPDTHGHAFGPNHQETLNEISNTDNRTAYLIRKLKEAEIFDKINLILLSDHGMEAIMVQRTVVQIIANEGKGDKLFTALSNHSKIYGFTILTKEEARFRFHYGQSRRILDYVLIADAGYAFDDFNVLLAKYNKKLNSTENHAREYGVHGYSPEAPSMRGFFICHGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6N0</accession>
    <name>A0A1D2M6N0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative leucine aminopeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_18043</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003351">
        <property type="protein sequence ID" value="ODM88640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6N0"/>
    <dbReference type="STRING" id="48709.A0A1D2M6N0"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903526" evidence="10">
        <location>
            <begin position="19"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="11">
        <location>
            <begin position="108"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="74"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM88640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="356" mass="40136" checksum="11A7A69C7D923D6F" modified="2016-11-30" version="1" fragment="single">MAFKLLLIISVLIALASLEETPEVEHADESTSPPTSRQSGVLFTFPKKPLHTRVVSSFVHPPEERADGAIRQRLERIPKSQRLQPQTGSNSQRRARHSRSPLRHQRSDGTPRRPGADDNASGCAVLMEVLSIIVEFGLKFNHTIEFHFYTANEGQKGSADVVFKYKQEGKKIRGMVNFDSLGFKSGDEIKLSRVEDQAGGGGLFSDQERCSSDYISWHRENHPWAAVTEINENPHRNTEMDSMDQVNFEQVNEFAKLALAVTIELGELALTPHIPDASWSSAFNSAPRNQVNIPHSFATTMFSEFDCFLKILEASWTTMWIFSNMTFDVIVEALRKIETLSTKHTLEGLWVSMIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7E2</accession>
    <name>A0A1D2M7E2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450 1A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_17770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003067">
        <property type="protein sequence ID" value="ODM88910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7E2"/>
    <dbReference type="STRING" id="48709.A0A1D2M7E2"/>
    <dbReference type="OMA" id="CKYSLIC"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM88910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10408" checksum="AE63AB4A4A56F826" modified="2016-11-30" version="1">MDCKYSLICYFVSHSKPRCTTLPYTEAIVLETLRLSSIAPLGAPHRMTADTLFHGYFLPKDTTVISNLWAIHHDPKVWGEDVNEFRPEKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7J3</accession>
    <name>A0A1D2M7J3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003050">
        <property type="protein sequence ID" value="ODM88938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7J3"/>
    <dbReference type="STRING" id="48709.A0A1D2M7J3"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF34">
        <property type="entry name" value="OS04G0183300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="68"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="315"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="575" mass="63815" checksum="B6232DD43030B8A5" modified="2016-11-30" version="1">MTLESVGNNKNGSFHSAGQFSFPKAKTDSETLTSLDADYSQCNGIDIREITITRLQELFSTNQLTSRELTSCYLQRIRALNPYLNAVIETNPDALSIALKLDKERKLWNHLRSPLHGIPVLIKDNYATRDRMETTAGSFALLGVQPVRDSDAVAMLRKAGAVILGKANLAEFSFFRGTNVPNGWSGRGGQVKNPYNLNFSPQGSSSGSSVSTATNLATATLGTETDGSLISPSSVASCVSMKSTLGLVSTRGIIPVSHTQDVVPFRIGIPREPFWVPEIVDSPILNDELPVLNKLLEKIKEHRLVTLIDPVNTPWERLRNISEVEVTVVLHDFKHDINRYLREETVQFPFKKIRTLKDIITFNNENPSPEGYNQDLLELSQTTDGLQNETYIQARSENLAVTKEYLNELLFKQGLDAIAVPSEPRYDTNSNPSLRHSPFVGWTVAAISGYPSITLPVGYDGYGVPFGICLVGKPYSEVTLLRIAKLIEETFPARKRPQFLNDKRLTSIKIKALLALLDQHPKNSSTISAKSTEIRNKAGGLRSHEELISLQSRLEECPSSCEASPSRWFMRRQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8C3</accession>
    <name>A0A1D2M8C3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucan 1,3-beta-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002784">
        <property type="protein sequence ID" value="ODM89237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8C3"/>
    <dbReference type="OMA" id="GTHEPHY"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903615" description="Glucan 1,3-beta-glucosidase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="43260" checksum="70B53E88F9D408F7" modified="2016-11-30" version="1">MIGNPVLILVLGLFALIKESECQLGVVYSPFVTANDNPESTKSYTLHDVKVMLNLIENDNFHHVSTYSVGAPDEPFKAGSTRNDCTSVVHTSIAAAEINKDKKQRVLSVYQGLDIASSSTVVKLNSEIEVGFEIAQAANRIYKGTVPALVLNAGNGFSRLFPMLGSIRNISERAQATQLQLGVRLRDCEAVAYILKTNKQNKFVLAQVEIFDFVICVKMPTLANYSAGPGAFSEYLKKGFLELENAVKETEIKTKVMLETGWPSGMNSSNPYETVSPKILWEMMGQWANKEKRLVFINEAFDSPSASSSNFTENPFPTHYGLWKHKDTDMDYSQTSYVRKGAKLQTHNTLANEDTGSNKPRNGAIAGRQVCGWFNSAVMVLAIVIADYTLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8G1</accession>
    <name>A0A1D2M8G1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Helicase SKI2W</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_17422</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002767">
        <property type="protein sequence ID" value="ODM89260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8G1"/>
    <dbReference type="STRING" id="48709.A0A1D2M8G1"/>
    <dbReference type="OMA" id="WERSQTH"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000447">
        <property type="entry name" value="helicase SKI2W isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="118"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="355"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM89260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1089" mass="125372" checksum="EB4B8470DADA023C" modified="2016-11-30" version="1">MLNKELAQNPVNFWEVKKTDTIDYEPSASKLAKQERQVKLLLKELDDDSFNPEEKKQEVSNVTSVLKISKTQSRNNPVIMPWAEDIDVTKPMFDFEQRVPNMAFKYPFELDTFQKQAIAKLEDHENVFVAAHTSAGKTVVAEYAIALSCRHMTRTVYTSPIKALSNQKFRDFKNQFESVGLVTGDVQINPGASCLIMTTEILRSMLYNGSDVIRDLEWVIFDEIHYLNNEERGHVWEEVLIMLPQHISIIMLSATVPNALQFANWVGEIKKKKIYVISTPKRPVPLEHYLYTGSGGKTRNEIFRILSGEGKFEKRGHDEAIEAKRSRQKSHEKQFGPKGGRNFMSEAAEKTTYIGLVSYLKDNDKLPVVIFTFSRKRCDQYAQMLRSTDLCTATQKSEIHSFFMKSIARLKGSDRELPQVLTVQEMLKCGIGVHHSGILPILKEVVEMLFQRGLVKLLFATETFAMGVNMPARTVVFDSTRKHDGMSFRNLNPAEYIQMAGRAGRRGLDTTGTVILLCKQNVPDSRDLQDMMLGKAAKLESQFRLTYSMILNLLRVESLSVEDVMKRSFLEAGSRNQNVDETKKKLQNVRNKVGELEWDTEAEERDPGLLRFYRQAKECIALQDSLVPFLKKHTRQNTLCIGRCIIFQRLPKYTTRFGIILDVHPPRSVYPDKLIVLTLTSNVDRIPLNERGLQVSDCEYVNLLVEGLGSNDVLDRIFLRFLYFCHNALCEFEPMLNEFDYFSHDVVEVEFAEVLDVTSLVMRVDSSSIMNDVRRRQVERFRREKPFPNVDTVLSTLVQMHSRPMEVMLLPPNQTLLPTKDLNLIQEVMRYQDCRANLKSHNYWTQWGDMSNFLTKFREVFCYMRLRDTEEYLDFLLSPRSLRLHEEYESRINVLKKLKYIDDENLVQLKGRVACEMGNQNELMVTEMVLNNVLADAPPEEVAALLSCMVFEVKSAEEPTFQQAGGLKERVETVKQIARSIGESQRECGMKEPVEQFVEQFKFGLAEVVYEWARGKASTRSTIEFSEIMKLTDVQEGLIVRTIQRLDEMIRDVKDAARIIGDPSLKRKMEEASECIKRDIVFAASLYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8J7</accession>
    <name>A0A1D2M8J7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002795">
        <property type="protein sequence ID" value="ODM89224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2M8J7"/>
    <dbReference type="OMA" id="MGENGIS"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1281"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1396"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="741"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="894"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="939"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1287"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1303"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1397"/>
            <end position="1407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1418" mass="142683" checksum="F17072BCE7D01584" modified="2016-11-30" version="1">MWEKLNFFGWNKKKEVQPVQREVSITLSNGDRQEVIQRSPSGTKLGSSSVKHGLDDDDSSEGSTSLNFGVKANASPRRNSSYSFSREPLDLPTWSNVTSPGFTSRLVQQASGHSPLKEFNDSLSFSPFRNSPHAHLQLGELPHVSFTRKPKLSPPVFPSPQKSLRSGVSSSVYSRDRRRNARQGTVFVRIAPIDPSTKANISLSGKTPSPNIASPSNGSPYPPRGSPRAGEPYRPEGLGGIPSQELAMRFNRMWSPPPGSAMSQMSGRPSSPTSPSNIVEALTAGRKRVREQDTYYGLPTSGPPSASSPPSKISVGIGDTPARPQMSKRVKFLGAPESQDRPMMVPYSGMVVVIASHFPNIEEQSSTLQSALRKRRNQSNIISANDEDTRGEKLGRFCRCNECYAEAAGVSSFMQPQTSQRSGSISASGSPNKSDDGSTSPGKSNKRETCDRGVSTEPDKIAFFREIFRKPNKKPVEKVDEIMKRPPVVLTKEMYDKDKQKRIERYYRILSMKPPDGSIFDVTLDPVAKPASDVNGEAGKTATTGSTSTTNNGAFSFGSQTPSTSSEGFTFNKQASPTAITNTTSVCSTISSPSSTGNTFGSNSASVTAPLMTLGTSSGLAGAFGTNTTNAPTSLAAVPTGSISFGTAAPSANPGGSFSFGKQAPSNAPATTNSASVGSTNSTTPLSSGTVSASTTETGASSTAPPSYGQSILATGASGGLTFGTTIPKSTTGVSTGGISFGTPASTTTPSTGFSFGKQTTSITPVQNTNTVGSSVSSLPTSTTGNALLGSTTAPAAAPSPFGQALASATSSTGFGSPISTNNDNKTGGAGSSAGFSFSSGSNPSPLLTANNGTTSAATTSTFGTLGPAITSTVSSTTVPTFGLTSSSQPPTFGSGNSSNTGTTLGSNSNLNTLPAPQPSTGGFSFSGAAAQNQGTPVTSSSFGGFNFGQSNNTSTSSPAPAAPSQAGAFQFGQSNPPSGSQTGSAIKSSDASDGTSLFSQATTTSSSTGSTFGSGGLASVTAPSATISSPFGQPLASGTSSSGLSGAFGSTTATTTAPVTGGFSFGSAPSTASGGFSFGKPMAPAAIANTTSADASITSPSSTGNAFGLNNSSNTAASANAASPFGQSFATGAPSGLSTGFGSTAPTNNMNNNKTATTGGFNFASVPNPLAKVTSPAPTFGSFGSSAATTAASTLSTTPGFGSFGSPATTAASTLSSTPGFGSFGGQATTAASTSSTTPSFGSFGGQATTTTTNSFGSVAPTTASQVPVFGSGNNNNAGFSFGSNTMSPPQSQPSTGGFSFGGTAQQQQSAPAPASSSSFGGGFAFGQSSTPAPLPPAPTTAPNPAGVFQFGQPAGNAATAGAAASSPFQFGQQAQQGVPGGFNFAAAAPAGMPNQMFSVGATNTAPRRRDPRRRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9Q3</accession>
    <name>A0A1D2M9Q3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock cognate 71 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_16972</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002431">
        <property type="protein sequence ID" value="ODM89708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2M9Q3"/>
    <dbReference type="OMA" id="WHEESHQ"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd24028">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Guanylate-binding protein N-terminal" evidence="6">
        <location>
            <begin position="52"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="424"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="528"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="885"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1248"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM89708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1534" mass="172429" checksum="4465B15C4E4534BD" modified="2016-11-30" version="1">MNLVISYNSQHRAIQIGSATSLSFVVAINMAKPCSSGKELLLLVSSESSKNSSLKVNDENLKQILAKVGKRQISIISVVGQTRQHERRLLLGSIIRSLEACEAAKSNSPEKPFLSDQLPELDRAVTWIFHRPFILKDEDGHQFALLLLDTQGSQQDLLKGREMASLIGLNLHLSSTTIISSSKQLPENLISRVGTFINHGLLPNREEMGDDEKTPFQTLTFHIRDWNFPVDFPFGGTGGNKFLDMKLQIKPAQNKESKQSRQLIRNCFQSVDCYLTPFPGQPAIMPGFTGAVEKLDGQFVSSMNEFLSSLLNNAKTPNGKGLTGQCLKIRLESYIQLFNSGVVPTSLTFLSRSHTALSQSQSDVGLPDESNLDQTSPTNSAIPGDSQLVKTALDAYNGIWKKHQKKDTFSATETNLLKTHKLAEKKAFDTLRNSEDNAEDYEKQLKLELAERFVAIQKECTEKRQLMISKAASECLDEYKDGVMAAFPLDNGIFDERQFVKVSSQLIARLNDDFEEKLGDGDDNAAAAESFQKRLKAEEAKYLAINNEQKHCSKDFSKAELEVVLAEYEKKMRGLTNLDPFMDNKTLKIWHEESHQSALKQLKLKWEKTPNYQDLVNQLEHSLNELFDKIQTDHSKLQEKYSAETEELISSLELSYSNELRQELNGMCTNAELEALHSQRVTGFLHRFQQQCHYPRGNFLLICNLEILKEKLESVLANVLDEKTKSKKAQDEGIKMAMEEAWTFYNEEMGDHIHTHVFLEEDALDKANEDVVDQAFDMYFNLLKQKSIPQHLAPGRNVLEQKFAAAYVSLKKQNVQNRTITISQTKNLVSDCLKDYQDSMNEGMNTVRNIETLTSLHEEMMSQAISGLQDKCAKKDDPQFLQPYINELEREILETFEEVEEIFELKLSKESGATNAALNEARKFYNEEMKKHFENHDFIRPDRLETLHKDVSKEAIRKCCEAVTLLSEAQKLELKEALKQTFEKYKQENDMNLEVDPAIGIDLGTTYCCVAVYMKGKVRIIPNAIGKYTTPSYVAFSQDRAETVGEPAKNRAYENPENTVFDAKRIIGRKFNDPVLQGDIKLWPFSVVDDNGVPKVLVNGKKLHPEEIAAKILRELKADAEKFMQCEVKKAVITVPAYFTDGQRQATIDAGQMAGLQVLTILSEPTAGALAYKKQHTDDEKPRNVLIFDLGGGTFDVAVLKSSRGEIEILAVDGDTHLGGEDFDRNLMKYCAEQFKTQHDIDLLFGKESDIKQMRDQVRRRLKRLQGECERKKIELTSARRVTVTVDNMHGTTDLVVPVTRDTFEQLNATLFEKTIAVVESALVEAKMEKSEVDDIVLVGGSTRIPKIQRMLEDYFGGKALDCSINPDEAVAFGAALKAAYLNGKIAKESIDFTKIQDVTPMSLGVEIYGGGFSVIIPKSTKIPVKLKERYKTAHNNQTSVQITIYQGEDHIAVNNKHLGDFYLNGIPPNDAEVENIDVEMLINSQGILHVSAVCSSTGDKSAISVTENKQRIGRAAIKRYLEEAANDVRGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA62</accession>
    <name>A0A1D2MA62_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002341">
        <property type="protein sequence ID" value="ODM89821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA62"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="8270" checksum="D9532A82FA0A2DE1" modified="2016-11-30" version="1">MDSIDFEVTDELAKTMSKGVTPSSLTKIKRKRNRENSTSSTESFELYNGSRRRSSVRSVLSKIVPNYDDFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA77</accession>
    <name>A0A1D2MA77_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynamin-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_16784</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002303">
        <property type="protein sequence ID" value="ODM89898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MA77"/>
    <dbReference type="OMA" id="TTYLQHT"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="3">
        <location>
            <begin position="29"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin-type G" evidence="3">
        <location>
            <begin position="678"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM89898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1337" mass="151294" checksum="97B140B1E711C4CC" modified="2016-11-30" version="1">MVMDDSREVIELVNKLQTYFKSTGCRNQKIELPQIVVVGAQSSGKSSVLDGLVGFSILPRGSGTVTKCPIIVQLITISGESEEEGIELEDYPEDGRINDNDDVRAKITELMEKNNGAITDTPIIVRVYSPHVVTLTVVDLPGIKRLTSAGEPSDLEKLIFDLSRKYINEKNAIILAVSPANYDICNSDGLLLAKEADPEGNRTIGVLTKLDLMDEGTDARDLLTGVSKDVQVKLGMIGLVNRSQKDIDNNFTVEQQMIKEKSFLSDTYPDLVDENGVPFLRKRLHELLVQHIHKCLPEILDKLEDLLEACTKRLDEIPNVLTQKDQFAFVSKIIYRFENHMKKELEGSPRSPEYDHLYGGIKIKEIFETLFARDMDAAAKKSDASITDAMILTAFRNSGSYDSMFVYPEAVFKRLALYQLQHIERPALKCAEMVNDQIMKIAERNLTGKNSNAFKHFPELRKLLKSVVTTMLISKLDDVKRLICDYVRVQSSVVFSMDERFKEKIADLKRKLERELHLGEEVVGTNNGTLPHVPIHSNSSSPTRSLNFYRPEGSNRNDPLCVKLKNPLIIKYIKEMVKYYFRLIKSQTQDYIPKLVDDRLIRQFSSDGSLGEELRTKVIESYEALTQLPLNVRESRKKDEQSKEHLKEVIAEVKAMLNSYLVNKLQAYFKSTGCRNQKIELPQIVVVGAQSSGKSSVLDGLVGFSILPRGSGTVTKCPIIVQLMTINSDIEDEGIELEDFPKEGRMQDYDEVRAKITELMEKNDGAITDNPIILTSTGEPSDLEQLIFALSRKYIQQKNAIILAVSPANYDICNSDGLLLAKEADPKGNRTIGVLTKLDLMDEGTDARDLLTGVSNDVQVKLGMIGLVNRSQKDIDNNFTVEDQLIKEETFLSKNYPDLVNQNGVPFLRKRLHELLVQHILKCLPEMLEKFEDLLEGCNKRLADIPDVMTQKDQFAFVSKIIQRFENHMRTEIEGSPRSPEYDHLYGGIKIKDIFEKHFAKEMQNAVRKSDASITDEMILTAFRNSGSYDSMFVNPEAVFRKLAQNQLQHIEKPAIKCAVKVNDEIMKIADRNLGDKNGNSFKYFPELRKLLKNIVTNMLDDKLDAVKAHIADYIRVQSSVVFSLDDRFLLSITGLRRKLEKQLHGGDEDSDGEKAKQELTNGEIVSQVGFPQSDPIYPFVHSKPPPLNGNGFRSELATAMNQLTGADRLCIKLKNPAIIKLIKEMVKQYFQLIRSQTQDYIPKLVADRLITQFSSDGNLVEELRTRVMENYESLTQLPTNIKESRSKDMKFKEHLKEAIAEVKGVLNSYNYEEDDLEIELENGSEDEFDYGCADEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAF9</accession>
    <name>A0A1D2MAF9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative cytochrome P450 4p3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_16763</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002293">
        <property type="protein sequence ID" value="ODM89919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAF9"/>
    <dbReference type="STRING" id="48709.A0A1D2MAF9"/>
    <dbReference type="OMA" id="NVARENM"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM89919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="516" mass="59033" checksum="F1CF3320F1027DE3" modified="2016-11-30" version="1">MSTFGVTEMGVGKGKELGVQWFLLTLVSFLLIVHLSQKKKQKDGGDGMARKRIPGPGQYVLGGYANIFALRNTKTSVNVLQQWGAKYGPIFEVQFGPFPVTFLNSPQHLQKLLGSNDTNYLSKGFAYEPLRPFWQDGLIVSSGEKWRSRRKLLTKHMFKYNSVLSFMKIFNRESDLLLSTLEIFYQDGKVKPLEHKIMTFSLNVITEAAVGLSADEVDRMARKEFQVSLIELVEKAKELMCKRILNPLLLFEPIWRLHPLSKLADVVTSAGRMVLSETFRKVENGKPEEKRGMQHVLHQAGVDFDGIFEEEITMISAGYETTASSIHFLLFFLALHPRHQELCREEIDAVFEDGDFCNAQTHLYYHALGQLKHLEMCVLEALRLFPSAFLLMRKIDAELQLEEDLILPANTNVAIFIPGIHKNPNIYPNPEEFIPERFSLKESKDTHNYAYIPFSAGLRKCIGYKFAMMEIMTATAKIIRHFYISTTSKMEDVILLPHITLTLEKPMQFLLTKRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAS2</accession>
    <name>A0A1D2MAS2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002179">
        <property type="protein sequence ID" value="ODM90080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAS2"/>
    <dbReference type="STRING" id="48709.A0A1D2MAS2"/>
    <dbReference type="OMA" id="MSCVENI"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903713" evidence="1">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="107"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="276" mass="32140" checksum="5A9F107495B354E8" modified="2016-11-30" version="1">MTKLYVSTLLLVILMWSCELSSISVEKYLTLTASQKTALDRFRQKVEPVLHASYMKQDTYLIQWLRDRNFDINSAEQKLLENLKWRKENGIDNMRNEDWSDMSLDIPVTIDTYDKTGRPIGVFDISDWDTRGIVLQGRGQRALRYLMSCVENITGQVYERQEKFGMNVTQVVVLANADGFNVIQHACPVCLPLWIQFVQLIESYYPEALDEFIIINATPAIQVVMEAIKPFLRKTNRDAIKVFDANKAKWMPYMDAKISKEERRKRYGGTKPPFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MB33</accession>
    <name>A0A1D2MB33_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002114">
        <property type="protein sequence ID" value="ODM90206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MB33"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903740" evidence="2">
        <location>
            <begin position="21"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="367" mass="39896" checksum="6B9A1D0641D03A95" modified="2016-11-30" version="1">MRTVMVLVVILTALIIHARGELVEVDPVPEPNGFNLNNVVAVSNTEDTPTIKVIPRESEANVELNLDPLTSIPEKRSPSELDVSLHPVNLLSIQETPSISVLQLPVDSADLTSTQEKRNAPKDGKAGEHKGVVIDNTAHHPQTTLKPTKHKPTTTPGGTHATTTPNGMSGRSLHPPPTKIPEQIAPMGRHFEEESAEEELTKAVTKKGANKTEEEINGQRRSHWAQVKVTHNGTGHNESLNGTDLEGVNVPDVDLASIPLQGSMWEQVKSTANALNISHCPDVDDFHSGSASIKGDLKKADTVKEDVEAVLNAASKSIVSMNHCLQRLFTDIKIAVDITKKRRKQKQLKVKAVQVSKKKVKIDLILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBN9</accession>
    <name>A0A1D2MBN9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UDP-glucuronosyltransferase 1-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001981">
        <property type="protein sequence ID" value="ODM90416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBN9"/>
    <dbReference type="STRING" id="48709.A0A1D2MBN9"/>
    <dbReference type="OMA" id="INIGIHE"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000021">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903778" evidence="5">
        <location>
            <begin position="26"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM90416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="527" mass="60749" checksum="50D17D5722723861" modified="2016-11-30" version="1">MKTTSPKLLLIISAQLFACAPILEGSNILFYHGIATSSHRTAIWPLASKLADMGHNLTYIFPVIKKIGSHPQIEEIIPSKLVPLLAEYVSDFDINIRINNKTSEWTMSVFSRALEFCEAFYDSPEIQEWLHRPDLHYDLVFIDASLGDCGYGLVHKFKAKHILFYSSVLPYMFDAFGVVPETSSIPEFYFHKKPSDMSFLNRVVTTLSPFIFRYNVIEFGKTLHKVLLKKMNLTELPTLMEFQRNTSLVFLNHHFIEEYPISLPPMFISYSGLWCHKEMTVNPLPEKFENFIRDSEGFVYVSFGTAVVASGMPESLRAKFFKAFEAFPDIKFLWRWTGSIPENTPSNVMLYPWFPQKDVLAHPKIKGFITQAGRPSIQEALCRGVKMISIPIMADQNYNADRLEYIGASINLNIDIITETNLRSAIDEVLHNPKFTDKLRELSEMYKDRSVDPLENAVYWTNYVLKYDTSLLKPLGMTQTWYERRLLDVYGFLLLVSLLLVVLLTFLAVLVYRCTLRIVFQPKIKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC08</accession>
    <name>A0A1D2MC08_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">O-acyltransferase WSD1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001915">
        <property type="protein sequence ID" value="ODM90536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC08"/>
    <dbReference type="OMA" id="TIVICAF"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009721">
        <property type="entry name" value="O-acyltransferase_WSD1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650:SF1">
        <property type="entry name" value="WAX ESTER SYNTHASE_DIACYLGLYCEROL ACYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06974">
        <property type="entry name" value="WS_DGAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="O-acyltransferase WSD1 C-terminal" evidence="1">
        <location>
            <begin position="330"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="479" mass="54761" checksum="E18CF84127DB0E5B" modified="2016-11-30" version="1">MRKFVSFLAHQLESDLEKLVTTKGVLIGRDFADWYTKPSHSIVVIMKLKGKLDLELLKQHVLRTNVRKWNVKKERLEYPELQQYCTLRFGYLFFKWDRKFGISNHVKLYKSREIHEGTVVTDEKIHEIWEKVARRAFKPKVSPWECLLIQNYDPEGKIHSVEELERLPEEERHSVVVMRVHHSIFDGFSIYRLLLSLSDQGLPLWEKETARKVPKYFNLLLNLKALFCGPTSLTKTFLGGIDVLHGLHYGHGRLTGKYTIVTTPLTIKVVKNASKLHKVSFHAVLIGAISGGIRKYLLKNGLSIPLQPMRVGIPIPQPNHTSKLRNEWLSAMVNLPVEKKTAKQRVVAADERLNKLKTGSLTPFLTQAMSLIGGLPVQVVRHLSRKSGVSVMYSEMRGPKDVKMTLFNKRVALREVMYSFGLGTDDLGVGFSSVSYDGKIHLILTLDKGIFNTKEKSDQFMQCILSEIEELQFGDSTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCD4</accession>
    <name>A0A1D2MCD4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterogeneous nuclear ribonucleoprotein K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_16047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001872">
        <property type="protein sequence ID" value="ODM90633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCD4"/>
    <dbReference type="STRING" id="48709.A0A1D2MCD4"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="2">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM90633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="9981" checksum="21B46106A06331BE" modified="2016-11-30" version="1">MFSHSVIVLPLLIKGGGVMKRGADRDMASPHKRARNLGQEIRILIPSRVAGSVIGKGGSNISRLRSEVSKKTVPLWMFAGEPSHMQQIMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-05-29" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCI6</accession>
    <name>A0A1D2MCI6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">G protein-activated inward rectifier potassium channel 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001826">
        <property type="protein sequence ID" value="ODM90717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCI6"/>
    <dbReference type="STRING" id="48709.A0A1D2MCI6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005242">
        <property type="term" value="F:inward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034765">
        <property type="term" value="P:regulation of monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016449">
        <property type="entry name" value="K_chnl_inward-rec_Kir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040445">
        <property type="entry name" value="Kir_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767">
        <property type="entry name" value="INWARD RECTIFIER POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767:SF102">
        <property type="entry name" value="INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01007">
        <property type="entry name" value="IRK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0407">Ion channel</keyword>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0630">Potassium</keyword>
    <keyword evidence="1" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="1" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel inwardly rectifying transmembrane" evidence="3">
        <location>
            <begin position="118"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel inwardly rectifying transmembrane" evidence="3">
        <location>
            <begin position="217"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM90717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="284" mass="32067" checksum="382355AFA4B8F399" modified="2016-11-30" version="1">MHHVPRFRSYKGFFTHLSLCDSTAYEREPRLVLKSGVLNAQEVNVEEKGQRYFADIFTTLVSMDIFIWIGLQLICVGDGPCSTFVSSMFSHGLATYFPFLLTSKEAQQFGLGKILICTGFAVIWWTILISHGDMDHFEEENWEPCVVGVKSFSSVFLFSLESQHTIGYAKKEVRRQRKTKALQTSAEMQMVKSKSQKLLKCKVWDNLAICFLPFVNLGHHRMTDICPEAIALLSLQSIAGVLIEALSVGVFIVKLSSKLDAHRIQNTTFFHTTVMPLAAVQSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEB8</accession>
    <name>A0A1D2MEB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras-related protein Rab-10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_15452</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001623">
        <property type="protein sequence ID" value="ODM91234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEB8"/>
    <dbReference type="STRING" id="48709.A0A1D2MEB8"/>
    <dbReference type="OMA" id="ENIRTWF"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000202">
        <property type="entry name" value="ras-related protein Rab-8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="174"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM91234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="213" mass="24124" checksum="92632132CEBA7C09" modified="2016-11-30" version="1">MAKKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFNTTFISTIGIDFKIKTIELKGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNLKSFENIAKWLRNIDEHANEDVEKMILGNKCDMDDNRQVPKERGDAIAQEHGIKFMETSAKNNINIDRAFHELAEAILNKTSRETSSSSGLPGSNMNAELQDRVNLNTNNKSNNRISQCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFZ6</accession>
    <name>A0A1D2MFZ6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14763</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001378">
        <property type="protein sequence ID" value="ODM91920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFZ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MFZ6"/>
    <dbReference type="OrthoDB" id="7544260at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006616">
        <property type="entry name" value="DM9_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11901">
        <property type="entry name" value="DM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008811330" description="Metalloendopeptidase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="23"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="353" mass="39151" checksum="E4250EA44760E36D" modified="2016-11-30" version="1">MGSKLPIWMGLVLLIPSCFSTSVKVGGRTWPNGVVKFHIHHGVPTVDRIEIQKAFDEFHSKTCVRFQHWQFGDYNWVSIERDNSVCGIAHTCQTGGYQYARFGGHCGTKAQIIHVLGHSLCLGHEDLRADRDANLRFGGCSRRPGRYMTNWYTARGIYDYASQMHPTCNSCHHGSPTKLNVTKCGSDATPGLSVLDVDSINSLYNCQGCHRHRWRPVELLTQQDRTNMITGFQTTSGTPLYPCRAFLEGRIIAGRFDNAANTCSFSHEGTHVHVETIGFEVLTIPGGISQQCGNYRLVNHTTVDLSKAIPVGTVVDDYKMRSYIAFGDNSVGNAWVHDGAGFGHFAEMPVNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGZ1</accession>
    <name>A0A1D2MGZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glutamate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14417</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001282">
        <property type="protein sequence ID" value="ODM92267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGZ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MGZ1"/>
    <dbReference type="OMA" id="MCEIIGW"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009449">
        <property type="term" value="P:gamma-aminobutyric acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677:SF10">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM92267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="347" mass="40147" checksum="607768FF267BAC55" modified="2016-11-30" version="1">MRGSVSNLYAIIVARHSMFPDYKKNGLRELPKPLVMFTSEHCHYSIKSAAMVTGLGTQNCVEVPADEKGRMIPAELERLVQKAISEGKHPYFVNCTSGTTVFGAFDPINELADICDKYNMWLHIDGAWGASILMSNKYRNPRFDGVTRARSISWNPHKLMTTHLQCSTIHFRERGLLRSCNSMHAEYLFQQDKHYDVKYDTGDKVIQCGRHNDIFKFWLQWRAHGTIGLERDIDHMMGIMEYQVDRFRSQPEKFYLIVPEPECTNVCFWYVPTRLRGMQHTKEREHLLGEVCSKLKQRMMEAGTLMIGYQPQGDIPNFFRSIISNPAVKRGDIDFMISELDRLGHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIB0</accession>
    <name>A0A1D2MIB0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coiled-coil domain-containing protein 102A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001158">
        <property type="protein sequence ID" value="ODM92738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIB0"/>
    <dbReference type="STRING" id="48709.A0A1D2MIB0"/>
    <dbReference type="OrthoDB" id="5984396at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46292">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 102A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46292:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 102A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM92738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="27283" checksum="05B68039FC71840A" modified="2016-11-30" version="1">MGDSHHFHHHHHHPRPKSQVFCDDEDDDMTMDRPSSSAGLIRHSETHHSVQSQNQKSELEQLRSRVCQMEKTLRWWSDCTSNWKHKWSQVRQERNTLRAQLKEITGGSVVPKPEVKSEAVQTDSCDQPSNATSMSTAADVHLLTKLLDEAQRTIGIERDEKLHLHRSIERLQQDLVDFNAMYDELVKEVQLLKLDDSGGGGWWWNRKQSSQYQNERCGSPHKFIIQRKTVDTPCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJH5</accession>
    <name>A0A1D2MJH5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LMBR1 domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_13472</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001044">
        <property type="protein sequence ID" value="ODM93216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJH5"/>
    <dbReference type="STRING" id="48709.A0A1D2MJH5"/>
    <dbReference type="OMA" id="QLERICY"/>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="626"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="634"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM93216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="666" mass="76280" checksum="00068D8E4FD7D6EF" modified="2016-11-30" version="1">MSSWQLGIDLVTTFLLASYLLFRYGNWYKHHVFVTLSVLVAWYFSLLFVFVLPIDISGTAYRQCVDWANSTLQNSTTNSTEPPCTVPPSYVSASVMTNLWRVVYWTSQLLTWLILPMMQSYVQAGEFTIKGKLRSALLDNAIYYGSYLFICGILLAYIAVKPDLELDWYKLKAIASSASNTWGLFLLVFMLGYGLISVPLTLYTSSSERRSLNVAYFKVAKLSTERSSAEEAIDDVIETLQLCVKSTNSLPPQLANNLQTIVSTLPVELREKMARRRVNETINEVNDKLLVKLHRNVKRALQAFNRTETQYERAITHAIYLEDVERSLNSGTRIFKHTFETSRAFWNHLPNSFEWFTRCVVHSYGLKVLSLMCWGLSFMIIWSEVTFFNKSPVLSFFALLLNSTRSVYPYMEFICTLTIAYMATCAFYTIFKIRVFNFYYISSSHQTDEYSLIFAGMLLCRLTPPLCLNMLSLFHLDSHVINKRILETSYTQVMGHMDVITLISDGFNVYFPIGILLVSIMTWFRVGSRILNKIGFQQFLPDDEIATELVNEGSQLVIREKRRRQRTLDNADRATRKYHSRADARASAAESANVAVENLRNLSTGDDMNDPDDNFYSRVLIEDSSSSRVRVYGTSPPHSATSSTTQHHHYYQNPDNAPPRGLFDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKS5</accession>
    <name>A0A1D2MKS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor Adf-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_13210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000976">
        <property type="protein sequence ID" value="ODM93472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKS5"/>
    <dbReference type="OMA" id="CELDITL"/>
    <dbReference type="OrthoDB" id="10051975at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006578">
        <property type="entry name" value="MADF-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039353">
        <property type="entry name" value="TF_Adf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12243:SF67">
        <property type="entry name" value="COREPRESSOR OF PANGOLIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12243">
        <property type="entry name" value="MADF DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10545">
        <property type="entry name" value="MADF_DNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00595">
        <property type="entry name" value="MADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51029">
        <property type="entry name" value="MADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MADF" evidence="2">
        <location>
            <begin position="9"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM93472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="207" mass="23870" checksum="9D5D9B12A9D3BF4B" modified="2016-11-30" version="1" fragment="single">MESLEKESQIIEIVKEYRVLYDKSTEGFKNKNKRLNAWASIGEQLECEPQDCKKLWETLRSQYMGHKRRLLKPSGSAAGSRPYFRHEASMQFLNDSNGEENSKTPEKVTLPVSDDDDVEEKEGEKITTSSVSSTVPRSSPQDFRAHKKFSGKRKLDAFDEEMLKLLKSSDDDEFKLFGDLVAVNLRHLNKQNPKKCRDLQLQIYSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMV3</accession>
    <name>A0A1D2MMV3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000843">
        <property type="protein sequence ID" value="ODM94201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMV3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="313" mass="34523" checksum="B749D17EB32B215D" modified="2016-11-30" version="1">MSVHSDSLVQVALQKSTHLSGTSKTSGCTRISVKSRRSHQTKTRSGGTAFPDSTTSVTSGGTHRKPTKWSNASSPVITPTPLMSTSVRLQQLRLCTLRDVSKVLQLWSHAVAPLHQWSEVESVAITNSFRHSIASGLSYIVEDVDPNGVPFISGCILANRLSYRDFEISTLMSPNYTFNAQVFTSQWQTMMWLFTHHVAFIAHILFVYKEALFITLPLVHPSVINGDLYDTCLIYTKMFFDVVSNARKKGLKLGLFIANGNLQKNVAKNVGFIPLCELPLPLGVTPVLGAPTLETLTLMVQYPHIHQPGMPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN12</accession>
    <name>A0A1D2MN12_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL52</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L52, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_12464</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000841">
        <property type="protein sequence ID" value="ODM94215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN12"/>
    <dbReference type="STRING" id="48709.A0A1D2MN12"/>
    <dbReference type="OMA" id="CEFCLIV"/>
    <dbReference type="OrthoDB" id="10249237at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034596">
        <property type="entry name" value="Ribosomal_mL52"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34090">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34090:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18699">
        <property type="entry name" value="MRPL52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM94215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="155" mass="17400" checksum="29118F6FF8DD6503" modified="2016-11-30" version="1">MMSNRVTKLVLGSYLPPLRVISKSRMLIGPESCNLFNCRENAFIHTSSHSHPCYVGSNWRKSRGLSANPNAYGPLTDGPDYSFIDGRPTPPGSRKIIRAMEQKAVAEKIMKLQGEVDFAVAHHETRVKNQEAQRKQILDSKLKPKGKLPPEIFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNJ2</accession>
    <name>A0A1D2MNJ2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Reticulocyte-binding protein 2 a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12067</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000782">
        <property type="protein sequence ID" value="ODM94607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNJ2"/>
    <dbReference type="STRING" id="48709.A0A1D2MNJ2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904325" evidence="3">
        <location>
            <begin position="20"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="368" mass="41533" checksum="DBDEAAD5A0254E48" modified="2016-11-30" version="1">MHCLKVMVVVAAVAVGTFGKPEPLSNQQQLRRRGVSRGRTGENVEPTPTAVDPLPAETTEPIFDPRAAQLGKSLDEREKQLTELDKNLKVHGRDEDLDARGRSIDKQVLETDKRLKEREGRIAAREKALGERESEIMKLAEAREQEIDRLTKERENAAELREKALEDREKALQEREKRVADREERVHKRMEANRKRFQRRRELRQLDERIGVVGGAKGETLTSSASTSKADITSQATTNHPRRVVEMVTFRKVTSAPREEISVGGPVTTSLSTDENTQVTEAVAYESAKEYVTPRPSKGDSATGIVPTEYSQPPENSLTPEVSSLKKRKGGKRRGQRQRRQGHEHHRKHKVRKVVKKMTNDGPVTVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP04</accession>
    <name>A0A1D2MP04_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000784">
        <property type="protein sequence ID" value="ODM94585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP04"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="572" mass="64500" checksum="50E4350E933FBA94" modified="2016-11-30" version="1">MAVPGTSFHLKNEKISASLSLLEHEESSDGGSGGHELPKEIIVPGHEVPVKPPPRARVHVFPSVGKFILSLIVTGLFLLCLPLIVVIYLCIGLVPRVFVRLLLSCSNGGRYSLMPISRGFGSTNDNHHTVMLIVRGRCDIEKIRKHMTKVLNSLDPCTGNKKFIHLQQRVAKKFGYLCHEERYPKFDIKNHVKHFDIRRKNIFLSFEDIIPLLETSYDEPFENVHTAPQWELLVIPKFAYVKDEAKLLGTSDRKQFYALIFRFHHGIMNWNMLQELLVEFLGKTSGRIRSIFSPATKKSRWTLLKTYLAVLFAGPLGFMNQLCHKWKRFGDLNITTPRISLSTTKPFDTEAFDDVKSRTFTTIDSVLANCVRIAARNLVLGQNLEVPRDMRVARVFNTMTCELQGVDSFSINFNKYSIALERLQGTFHAIERQQGACSLAAQRLFNKTVMLLAGVFPYNLSAWLYKVLLKGDVILEVWPGADEPCTIFGDDLIADIVGWAGISGVDADMKVTVTTYCGRVRANFTGRQGFFGSLTDSQILSYEFEEEFKKLAAIAGIYQSRVFLPPAVDNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQQ8</accession>
    <name>A0A1D2MQQ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000706">
        <property type="protein sequence ID" value="ODM95134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQQ8"/>
    <dbReference type="OrthoDB" id="6365503at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="23233" checksum="87D51F2179710B28" modified="2016-11-30" version="1">MAGYSNGIPNGVKNGNGKRERMDQDDDQEFMPLSKRINNIHLSPERLHNGLHMHGNSSMMHPNHHPHNIGNGYPEKSSDQISNYQNCNGVHGHPHLHQQDGARSSLEFMDRNLPSTSSSNSHHQIHHNLQVPNMIVSHPDLVGATGRSEIEYRPSMNQSANPHYYESNRALFNLYIERQLRNNQNPHPNVFNDSISDITCSNNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR97</accession>
    <name>A0A1D2MR97_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11269</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ECSIT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000677">
        <property type="protein sequence ID" value="ODM95421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR97"/>
    <dbReference type="STRING" id="48709.A0A1D2MR97"/>
    <dbReference type="OrthoDB" id="10064298at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007178">
        <property type="term" value="P:cell surface receptor protein serine/threonine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029342">
        <property type="entry name" value="ECIST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010418">
        <property type="entry name" value="ECSIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046448">
        <property type="entry name" value="ECSIT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13113">
        <property type="entry name" value="ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13113:SF1">
        <property type="entry name" value="EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14784">
        <property type="entry name" value="ECSIT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06239">
        <property type="entry name" value="ECSIT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01284">
        <property type="entry name" value="ECSIT_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0391">Immunity</keyword>
    <keyword evidence="7" id="KW-0399">Innate immunity</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="ECSIT C-terminal" evidence="13">
        <location>
            <begin position="373"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="71"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="555"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="569"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="606" mass="70263" checksum="04A5F58DBEC143E6" modified="2016-11-30" version="1">MLPRVPRCVFQRSLGRLAKYVMVSSTSNDLPLNTLLYRRHSTISSRLLHCNCGIVTTHLFNKNTSDLQQCRYKSTKPQTKKDTSGSAVRERDNEVDENASKTNNKLDDEDEPSNQVVVSSESSKIQLHRKAAASSDELIIQRTAEEEEKSRRRYEKADPPEEERHEYHKQRAERSVNKALMKTDMFDNMKEKNKENFLFAVELFEERDVHLRGHVEFIYAALKEMKKFGVHRDLETYKKIIDIFPKGKMIQTNMFQVEFMHYPKQQQCAIDVLEQMEDNSVIPDTEVQQMLTNIFGSWSFPMRKASRMLYWMPKFKHLSPWRLPENLPDNTIELAKIAVERMTSVDLNTKITIYDCAELEDAYDITWIVSGQSPEQQKLIESHPAERPIFVEGAFRLWLKDVCMNYFILRAEPKPRVDSKKDLDEVGDIHTVYEEEFIDALETVPTVHEQEDGVILGVCCTGSSSRDSVVSWIRFLEQTNPRLGKDISVLFTLKSPIGPTDDLEILAYRDIEELQKLGKQRDPFIASSKLGVDPGMPDLRQVGIWTDSDTKFPNWPHNFHNPDSTSLKNKMENEQLLQELERRAEKKPQKIGDKDETKPDENKQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRE7</accession>
    <name>A0A1D2MRE7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynein assembly factor 3, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_11023</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Dynein axonemal particle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNAAF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000639">
        <property type="protein sequence ID" value="ODM95647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRE7"/>
    <dbReference type="STRING" id="48709.A0A1D2MRE7"/>
    <dbReference type="OMA" id="WWGYSPA"/>
    <dbReference type="OrthoDB" id="538817at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120293">
        <property type="term" value="C:dynein axonemal particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044458">
        <property type="term" value="P:motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039304">
        <property type="entry name" value="DNAAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028235">
        <property type="entry name" value="DNAAF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 3, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118:SF14">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14740">
        <property type="entry name" value="DUF4471"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4470" evidence="5">
        <location>
            <begin position="18"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein assembly factor 3 C-terminal" evidence="6">
        <location>
            <begin position="152"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein assembly factor 3 C-terminal" evidence="6">
        <location>
            <begin position="322"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM95647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="442" mass="51124" checksum="EDD862E28D2AAF3F" modified="2016-11-30" version="1">MNRYVTDYVNGRGVLNYWGFTPALDLSSLIDVTPNNGDSKRHIKIYFDGLSDSRHILQTLAKGLSKQDGLEMQFYISESNMCIYARQLVLLQIAFAPLTRVGLHEKVCAFMELHGNLCIRPQTKRILKEICEELIMAVTDDDHARKLMPYITFKELRFKERDLVHQYLRRWRDAAASTIPLSTAWDKQLRASLGTRYDSRAGSFDWDYNMKVLEKDPKLRIIHANEYKKWRETGMAYVENESDYSQPNVTLSEGASDNAPTYSGDMEVGPYIPYGVNCEEASLLEKANDQYKKKSYDIAFHNIQEMLSILSPPDETGRPAFFQNFMVWLLPIGSSQNLWVKSKFANIFDVAFLSTHSFLGLRCELVRMLKPHAIVFFEKPRYIWWFDKENVPAFDKEVEQKAKTANLVSYPLDVKDVSETLYRFKISEDTNQTNNSNNSNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRW9</accession>
    <name>A0A1D2MRW9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000667">
        <property type="protein sequence ID" value="ODM95465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRW9"/>
    <dbReference type="OrthoDB" id="7457895at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="87" mass="9870" checksum="1FF83E4839C4C12E" modified="2016-11-30" version="1">MRNLSEEIQKEHPELSGGNVETTMSFLTHVYSAWSCLVCHQIIMGSMLIHGIRMERLSLLKVWMIYEGCALALSFILNISVALCEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSU4</accession>
    <name>A0A1D2MSU4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000613">
        <property type="protein sequence ID" value="ODM95854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSU4"/>
    <dbReference type="STRING" id="48709.A0A1D2MSU4"/>
    <dbReference type="OrthoDB" id="10261302at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="10"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM95854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="92" mass="9891" checksum="99D3304C8203D7C4" modified="2016-11-30" version="1">MGVDASCGPEGLRPIHIAAREGHIQTLRFLKTAGACLQKSDVNGATALHHAAITGQLRAVRWLLRHGAKISLDKQGRSPIQVAADHDHMEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTS2</accession>
    <name>A0A1D2MTS2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000582">
        <property type="protein sequence ID" value="ODM96095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTS2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904521" evidence="1">
        <location>
            <begin position="20"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="162" mass="17892" checksum="2CE6BE852E734171" modified="2016-11-30" version="1">MRSFLQLLVAVLTIGCFFGTIVNVEGQAKRNNALCYTCLNKDCDDLLTSEIKKCEYSVDSTIACMTYLNPSKEVIARGCGDDPVKSCFDIDDAFLKSKKCQENTAPCQNGTTTPMPWDIVKPMPDDMLLCPCVGDLCNIGSGASRHSIRLVMGFVAIFWYFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUZ3</accession>
    <name>A0A1D2MUZ3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000508">
        <property type="protein sequence ID" value="ODM96742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUZ3"/>
    <dbReference type="STRING" id="48709.A0A1D2MUZ3"/>
    <dbReference type="OMA" id="PREIRWE"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="83"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="30807" checksum="7DFF85BDC7E5800B" modified="2016-11-30" version="1" fragment="single">MGATDNNDEITTRERELIIQLRERVQNELPLVELSKSEEDQDLFLVRWIRARDNNLDKATDMLRNSLNWRKEHSADELSKIEIHPFFVKNYPYKWAKTDKFGHPVMIVPLSEWDYRKIGDESNLQKEYENFLIQFYEDIMNHIKMAHGSREIGNPPITQLLIIMDATSYPFGQLFSISAFKKIVQSAVVYEAHYPEILFKAIFIKCPSYFGTVLNVMKPFLPAKTFGKFFCYSSMEEWKKDMIDLVDPAILPQRYGGTSSEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVS0</accession>
    <name>A0A1D2MVS0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Eukaryotic translation initiation factor 2-alpha kinase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_09672</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000479">
        <property type="protein sequence ID" value="ODM97011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVS0"/>
    <dbReference type="STRING" id="48709.A0A1D2MVS0"/>
    <dbReference type="OMA" id="LDSKMMR"/>
    <dbReference type="OrthoDB" id="6778822at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990625">
        <property type="term" value="P:negative regulation of cytoplasmic translational initiation in response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000722">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="54"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="230"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM97011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="416" mass="47203" checksum="23DAEF0EA726444F" modified="2016-11-30" version="1">MSINKGPNIHGLNDRAQHNKDEEGSNEEDADPALPPRIASTIPFSAHSRLHNEFQVMEWLGKGGFGDVLKVKNKLDSRIYALKRIKLNPRNKQLNKKITREVKLLSQLNHENVVRYFNSWIETVEEDETEESTNTDSMSTAEITPPKNKFRKEPSVRFQLEKIPELNQNSLGFTDNIEDLAPPIKDSEWSMSFANDAENDGDDSEDSSDEVDLFGTSFLRLTTDDSNDVIFESDSRTGASETDDTAEESSRSKRFPIESSHVPTTNDNVSPANLPLHREAQYMYIQMEFCEKSTLRTAIDDNLYEDLDRTWRLFREIVEGLVHIHQQGMIHRDLKPVNIFLDSHDHVKIGDFGLATSSILPKYVLHKNEGPHSVDFHEDSQTGQVGTALYVAPELITKGVKITYNQVSINISIVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVW7</accession>
    <name>A0A1D2MVW7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000475">
        <property type="protein sequence ID" value="ODM97068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVW7"/>
    <dbReference type="OrthoDB" id="8296303at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22512" checksum="B7FDFB21F9C5D5BA" modified="2016-11-30" version="1">MVVNLLPCMALQKGTMLLAVIDAMISIVNVGTLVIGFLIFDKDDPDFSNGEKIITLVVLIVVTIMCILQIALAFKLYMAAINKNYKSCRLWMIISAVVLIINVLNTTVDTATTDFEGTSLAGNVIAIIYKIYEMLVVYAFLQELKSNEAMALKTSPQLGIRSGSPVFTTEESLQPQHSSYPMQTFNYQASGQTAATTQLGPMVVTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW16</accession>
    <name>A0A1D2MW16_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-hexosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000471">
        <property type="protein sequence ID" value="ODM97121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW16"/>
    <dbReference type="STRING" id="48709.A0A1D2MW16"/>
    <dbReference type="OMA" id="RQGENAY"/>
    <dbReference type="OrthoDB" id="5806726at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006689">
        <property type="term" value="P:ganglioside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF21">
        <property type="entry name" value="BETA-HEXOSAMINIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="483" mass="53719" checksum="FEC0D14C2E5F9E23" modified="2016-11-30" version="1">MNAEGGISLKEKILQELVVPEGTFLHLASKLGLQDVVRALLTAGANPVVENRQGENAYEMATSETIQQVYVEELLRAAAKSDIARIDQLIKAGVDPNSWDCDEKKNTVLHWAVSFGNAQTVKYLIGPESPLFPKENSLRTPSVNGHHPNVTPESVEYIPLHPGFNACLEGVIRGLEWKAPIHPIVTDTNLSLLWPQPKSLHQLEGLHFRPEKILHLSVIKSAESVHRILDIFSTHKDVFETLGFDVTAQQVENSISHDSNQSSCILSSQIQCCVNPDILSLPNSYRLHITSQKVRITAADLCGLNYAISTFLQLLTIYSKEEPAGIPPLIINDSPSLKHRAVFIDVTQERIPTIESLFEIIKTLGLLKINYLHLHMRLDKNGPPLSYTKGEIVAIDRNCQDACITLVPAIDIPFGISATEYFQFIKPCYMEFLPVSEVDSIVMMCFNALKTHITNPSILNTVPTNVVLVEYGFQADYHFGALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW49</accession>
    <name>A0A1D2MW49_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Echinoderm microtubule-associated protein-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09646</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000477">
        <property type="protein sequence ID" value="ODM97034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW49"/>
    <dbReference type="STRING" id="48709.A0A1D2MW49"/>
    <dbReference type="OMA" id="GWGAHGD"/>
    <dbReference type="OrthoDB" id="2105077at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000320">
        <property type="entry name" value="echinoderm microtubule-associated protein-like 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF50">
        <property type="entry name" value="ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EML-like second beta-propeller" evidence="5">
        <location>
            <begin position="20"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="215"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="27484" checksum="7661DCEEBF26C752" modified="2016-11-30" version="1">MLCWSCDCLTSTLPPSLVCEAIQSACFSPDGSVIVVGTVLGHWFAISAETREILSHHNDGSEPIQVVRFSPDGKMLAIGSRDNIIYIYQASDNYHKYNRIGRCSGHSSFITHFDWSSDSTFILSNSGDYEVLFWNASVCRQIPQSSQLRDTEWATTTSTLSGATIGIWPENADGTDVNTCDRSHDKKLVATGDDFGKVKLFSYPVTQPKSLCHTYGGHSSHVTSVQFLPDDTRLVTTGGKDSSVIQWVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW67</accession>
    <name>A0A1D2MW67_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000456">
        <property type="protein sequence ID" value="ODM97297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW67"/>
    <dbReference type="OMA" id="DYRIIWL"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="277" mass="31089" checksum="DCCE71340B502B2C" modified="2016-11-30" version="1" fragment="single">MDSFDQKDDQEPPNLEDFEEEEYEDDWIEDEEDEDYDEEEEGEEEEEEEEEEPLPPFDESGRDYRIIWLKRQLCLYLNLLDPDVAEELLANEAVASGFLEFLESDLGAMNQDDADKLRTAYFFKVKVESDEVVVEAAPEEEEEEAEEVVELFDETTDTEKGKKRGKKGKGKGKSGGGGKKGGKSKGGKKKDKGVGSKAEKSKGGSKAEKSKAEKSKASSSEKSAKSKTSEKSKKGKGKKSKKGKKKKKKDEVTEEEPPSVPIVYPWDEDTDLDVESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWS5</accession>
    <name>A0A1D2MWS5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pollen-specific leucine-rich repeat extensin-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000437">
        <property type="protein sequence ID" value="ODM97507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWS5"/>
    <dbReference type="OMA" id="FANINIC"/>
    <dbReference type="OrthoDB" id="8292392at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="558" mass="61870" checksum="D95C2C48ACA03263" modified="2016-11-30" version="1" fragment="single">LSTQTLSQVEVEVSDEANSTASSFNEVLPPNLSLQHELELCNEHDNISKTYCKCGGGVVDCDFSKFSTHQLNHTMELSISGYAIPSTTRKVCICNAPNDLSLTFIKTFLPNRNKIHRFDLYNLKGDTRLDGAFSMFFTGDLYISNVTRIPEIHGYEFGRGYDDDKLENLQDMGCCSPIKVNQNFKKPLLFIENTAIGTINSGGVGDTHLWKTVIFKSVSIDLVQHYGISSFNTQTDVAIIKSIFTNVADSGIHLEGATNLFLAKSYFKLDSNHFAWSSKSKLKDSNVVLLGNTFWYPIIHEIDASRIVAWNNIYLTWGDNVTFNDMRFSSFTERFISIKYNIVTDNLVPYSIPFSKGSQVVLKENVLGSCNCSQYLVEVPFIKRDVNRCFAGNISDPSSGKCSLSLEAVVKACSKSSAPNFNEMCRDKSIATNSTFPGVGTDVMTGVEKARVNSTFITTIINEYPKLIGVNHIATTDGFLVNSENPWQDDESPANNDDGSSAHRTDSTQSGSGTAVTVTIILTVLVIVSVAVIIGYRNRHRFFGRSHQRLDASREVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXB6</accession>
    <name>A0A1D2MXB6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-coenzyme A thioesterase 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000442">
        <property type="protein sequence ID" value="ODM97444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXB6"/>
    <dbReference type="STRING" id="48709.A0A1D2MXB6"/>
    <dbReference type="OrthoDB" id="46529at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="93" mass="9723" checksum="D8C3D43B4BD4A63F" modified="2016-11-30" version="1">MASRAGLELVQKMMAQRISSGCIDQLLLNKVKVTSVGEGTLTAVMTVEKEHANIGGTLHGAMSTYLVDAMSTLTLATCPGVKNVGVSLNINMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXB8</accession>
    <name>A0A1D2MXB8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein MEMO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000428">
        <property type="protein sequence ID" value="ODM97608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXB8"/>
    <dbReference type="STRING" id="48709.A0A1D2MXB8"/>
    <dbReference type="OMA" id="NTICGKS"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="178" mass="20085" checksum="ABDCA40EF882DF1F" modified="2016-11-30" version="1">MNLSVDEDEHSLEMTIPYVAKIMEDCKNNFKIVPVMVGSLTPEKEAQYGAIFSPYLADPSNLFVISSDFCHWGGRFRYTYYDQSKGAIFESIQHLDRQGMDIIEQLNPSAFTDYLRKFGNTICGRHPIGVLLNAVNSLPPSEKAKLSLRFLKYAQSNQCYNQTDSSVSYAAASLIFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXL6</accession>
    <name>A0A1D2MXL6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000442">
        <property type="protein sequence ID" value="ODM97435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXL6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="64" mass="6141" checksum="5A50D036AB4023ED" modified="2016-11-30" version="1">MARPGAPPGMPGLPPGLPPGVPPGMPPGMMGAGVPAGPPGMPPMRGPPPGLMRGVPPPPGRPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXL9</accession>
    <name>A0A1D2MXL9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000409">
        <property type="protein sequence ID" value="ODM97796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXL9"/>
    <dbReference type="OMA" id="WIKDHEH"/>
    <dbReference type="OrthoDB" id="8250415at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="16"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="155"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM97796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="23506" checksum="7AEC319A5D8082B0" modified="2016-11-30" version="1">MILSATSSSEEMVPEAIDHVGIIVYGHLYEYGDLGVLRSVVPLESDPKSKYPVFQLRSRETLGETTKTQEEFEAWVAEQNEGPFQGSNYDVVTTSCVVWAMHACNFLEIPYPENWDKLCDWAEENKTVAGLFGGSGVASRRVQIRVPQKIKTFAKKHFKRDSKTNDGSKEEAEDDETEDNESKEDDNEVKEANEDDDEINNTTQSTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXT4</accession>
    <name>A0A1D2MXT4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein msta, isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08822</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000401">
        <property type="protein sequence ID" value="ODM97856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXT4"/>
    <dbReference type="STRING" id="48709.A0A1D2MXT4"/>
    <dbReference type="OMA" id="TRNIKPY"/>
    <dbReference type="OrthoDB" id="5952526at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF4">
        <property type="entry name" value="GH11294P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="14"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="53"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="586"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="614" mass="69344" checksum="5BE7369BBAA910B1" modified="2016-11-30" version="1">MVGQEKDKKSEDQCALCNATANSRCGGCSKVSYCTKEHQKKHWKIHKGECCAWKVCESTSLGRYLTAVRDIKAGEVILRERPILLTPPKVTPAICLGCYREFNTDPEEQVQREYVEPRPCPKCGWPMCQNDECINSPEHAAECAIAEARGGAVIRDFNVDHPVYRSIGILRVLGLKDRHPDKYQKLLNLQSHSEKQRLEDAKAADSSSLHSNAAALGRFGGEYPEQRSEIERDKVVTVKVVRGFFQRKDVDEDTILNLISIIETNGHEIPIPNARGHINRRLIGVYNNTSFLEHNCKPNCVKTFDMADKAIVIRSAVPIKKGTNLSISYVDPLWGTNDRCNFLQMTKYFTCKCTRCRDPTELGAHVSSLRCQSLKCCEKTGLESLVIPEDPFAPEKDWVCIACKETYPVGYVSSIVNKIGKDMDELHEKFGDIPAIEEFVKKSSKFLSPFHFYLLEMKVELAQLYGRTPDEPILALAPRKLLRKIQLCEELLIVLNKIYPGYNRLRGIITYELQAAVCTLSKMKFAAGEIPLDKHLDELMQCGKWMTEVIKVLGWEPENSIEKQRADGAAQDLQLLKSMVLSIQGDQNEGAQPSTSMDDMDNSPDRESFIEEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXZ5</accession>
    <name>A0A1D2MXZ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">DDB1-and CUL4-associated factor 12-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_09135</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the WD repeat DCAF12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000433">
        <property type="protein sequence ID" value="ODM97545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXZ5"/>
    <dbReference type="STRING" id="48709.A0A1D2MXZ5"/>
    <dbReference type="OMA" id="WQVDPDM"/>
    <dbReference type="OrthoDB" id="9610195at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056151">
        <property type="entry name" value="Beta-prop_DCAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051191">
        <property type="entry name" value="DCAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19860:SF16">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19860">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23760">
        <property type="entry name" value="Beta-prop_DCAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DDB1- and CUL4-associated factor 12 beta-propeller" evidence="12">
        <location>
            <begin position="152"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="255"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="293"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM97545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="464" mass="52168" checksum="357F3E7FF7EAB996" modified="2016-11-30" version="1">MDMNRRPNNAGNNGSCRAGSDFFMSGVPKRPICGSKTAASSYRHSKKLLKRLKSTLSYGDQRLYTSRSFQEGSNKYEEFFCYNEHEDDPEDDEDTRGGASLFQNISLNMVDFLNERQLGNIRQPFNLQPRVMLSESFQHHPDLPIKHLLTNQILQEKAIKIENLNKVFCSQWLSDKQVIFGTKCNKLMVLDVQTKHLTQIPCLAPSPRSLPPDSQCGIHAIQINPSRSLLATGGRNPNDLAVYRLPTLDPLCVGELAHQDWVFALAWLDDEFLVSGSRDTSLALWKIPDTVEQPTYNSSSITERERPLDLSNSQPNSQSQSSSNFSNAVPSYSYINAVAVKQCKSAQKVRDIVFNRKLQEIACVSLNGYIHIWSADRFVQKYSRKLPFSMENVCLAVHEDYNLYAVGSKSHTSLMDARTVQCVRKVASKYSGFGIRSTSFYSSILSIGTGQDQSCSMISALENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYE9</accession>
    <name>A0A1D2MYE9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08592</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000382">
        <property type="protein sequence ID" value="ODM98087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYE9"/>
    <dbReference type="STRING" id="48709.A0A1D2MYE9"/>
    <dbReference type="OMA" id="HLECNMH"/>
    <dbReference type="OrthoDB" id="10017443at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018795">
        <property type="entry name" value="K2013-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31386:SF2">
        <property type="entry name" value="SIMILAR TO RIKEN CDNA 2510039O18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31386">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN KIAA2013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10222">
        <property type="entry name" value="DUF2152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM98087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="600" mass="67626" checksum="60164E477F028562" modified="2016-11-30" version="1">MLIRKLFTFTILIFFLLWIFGFRFYSQVHVESPGELNTCLERNLYKLKGEVEQLDSNILHMPPLEDENQYLPYVGNGYIGASVMDDSTVKIKARHGRTLQAVIPFRPMVSVTLADESSRKEATVSQFRRGTVQKFSCIERSQEEVVEAASIYYAHRTYPSVFEQDVTVRNTGSENVIVQFDQLAYSGDPPFKMEVKKFELPGGKGDYQAVIASGIIEVDRVSIAVAIASKKVPNAVEVKANKFVSFRFVSVINYSYLNSKKDFESVKTVLTNKSEMELQKVMSQDVRAFFELHEKAWNELWTTGFHISTSRAINALNGDKINATMYNVLSQVKAPLFEVNVPLSHIAEANSVLSYAEGCYGGHHTLQAPNLWSSLESETDILTVSNLWLITLEKLGCHRLLRAGASGVMQAMVLSFGALKFSNHHLEFNTEPKDLHRDYLFRRIGYGNATHVNISVSVGEDNKAVLSAALDRSDRDYYACDAGCLDAPVELAPTKKQFPVKLTDPVTSILYITSDRKHVEELRLSIHVKEVLEAPAHETHVISMHKHGSGYGAMSTMFWVGLSLLIILFHLFLFHLVYTEYFAPSPDKYRTSPAVFLRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYN8</accession>
    <name>A0A1D2MYN8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-taxilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_08524</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000377">
        <property type="protein sequence ID" value="ODM98159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYN8"/>
    <dbReference type="STRING" id="48709.A0A1D2MYN8"/>
    <dbReference type="OMA" id="ETSCATH"/>
    <dbReference type="OrthoDB" id="425555at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="174"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="323" mass="37235" checksum="7E4FD2AF2C2334A0" modified="2016-11-30" version="1">MDSRDIEGNKGSDREKSLREENTSLKTQLKELETTYSSLQAEFSKSIKMRDRLDSLCKELQKQTLSIKEESAAKIQEAETQGNQLASEVTSNMGIMESVHSNLATTTNESIAAKKANADLIGQIGTLKEHYDNRQKDLTVTLEETNDGLIRTKLELSELRMKYAQDREKTYGDMQKLATSLVESRQQMKNAKELELELRILIQDYDQKFSQLQKALEETNVAYGVFKDDMDKVALRAKELETETMLWQKRWDESNEELSGMTKNHHELQTNLCNVHEKLIKITGLYRVLEKERYDMMTKLGRQEQALAKSAVELLPPERFLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYR7</accession>
    <name>A0A1D2MYR7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dephospho-CoA kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08504</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000375">
        <property type="protein sequence ID" value="ODM98179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYR7"/>
    <dbReference type="STRING" id="48709.A0A1D2MYR7"/>
    <dbReference type="OMA" id="CQMDIEQ"/>
    <dbReference type="OrthoDB" id="247245at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02022">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000485">
        <property type="entry name" value="Dephospho-CoA kinase CAB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00152">
        <property type="entry name" value="dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="230" mass="26183" checksum="0A7E83463D54B886" modified="2016-11-30" version="1">MFLVGLTGGISTGKSTVSKLFTALSVPIIDADIIARRVVQPGRRANKRIRKNFGDEVFQADGNLNRELLGKIIFNDANKRRQLNSITHPEIFREMCWEILYYFGKGYKFVIMDSPLLFESGTWVNYLKCTIVVSCEENLQLQRLMQRNQLSETDAVARIKAQMPLSEKISKADYVIENSGTLEDTKRQVTEIYNKLDNSKAYLTVRISAFILFALFTGGVSVMISWFFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZK0</accession>
    <name>A0A1D2MZK0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000352">
        <property type="protein sequence ID" value="ODM98467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZK0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="41" mass="4691" checksum="B98C936A2C148F05" modified="2016-11-30" version="1">MYQYAPHLVLHHTVSHVCLVVEVIALLLEHCLRSAAMNQIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZM1</accession>
    <name>A0A1D2MZM1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6">6.2.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Long-chain-fatty-acid--CoA ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_08194</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:54537"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tetracosanoate + ATP + CoA = tetracosanoyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33639"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:31014"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:65052"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:33640"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6"/>
    <dbReference type="EMBL" id="LJIJ01000349">
        <property type="protein sequence ID" value="ODM98486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZM1"/>
    <dbReference type="STRING" id="48709.A0A1D2MZM1"/>
    <dbReference type="OMA" id="KIALIME"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000002">
        <property type="entry name" value="Long-chain fatty acid transport protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="11">
        <location>
            <begin position="72"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM98486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="657" mass="75142" checksum="30E92C8C0864FD72" modified="2016-11-30" version="1" fragment="single">MAVLGFGLGTLFYLFYCLVLGAVTVIAVRNLKLVYALILTLPRDVVATWRYLRTHMFTKWTSFTNQTMFSMFDKQVKKHPRKVCWYFEDQVWTFKQVQDMSYRVGNYFREQGFKKGDKIALIMENRPEYPIMWLGLSRIGVTTALINWNLRYQSLEHCIKIVNCKAVIYDADLSNGIGKHTILMMNMFIKNMPSLFLLAIQEIYDCGGLKELKLYSMESNRPESTRAIPQSVNLSAELKEASSDPAKCKVNIDKYDPLVYIYTSGTTGLPKAAILKHHRAIMFSALYIFQDIRPDDVMMTPIPLYHAQGGMIGVGLAFCHGVTQVIVRKFSASAFWKQCVKYDVTVCQYMGEIIRYLYNQPECPEEKRHCVRFFYGNGVNLEIWKKFVERFKGIKIQEMYGSTEGNVTLINFEGKWGAVGCIPIWYWPFVPCGMVKINEVNGEILRDPKTGLGIQCQPNEVGEMIGVIVRGDPLREFDGYTDEDASHSKIAHNVLSKGDTVFRTGDLIVRDIYNYFYFKDRLGDTYRWKGENVSTTEVEGIVQKSSGLKAAVVYGVKIPGTEGKCGMAAIEDPEDCLNLEEFTKEITKALPFYARPIFLRVMKGIKITGTYKLQKIELQREAFDIDKIKDKLFFLETGTYVPLSRELHGKIVSGQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZN7</accession>
    <name>A0A1D2MZN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000381">
        <property type="protein sequence ID" value="ODM98115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZN7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="244" mass="27294" checksum="A6946E9577B967CE" modified="2016-11-30" version="1">MQPQAPNKLDVDGNCVAISTTLTLNLYGAPSTHFAIGLNNGLIPTDESLEKIYVFGVVPSLTPEGKCIFKGVWIPINFQAGILEHLAPKHALVVAQNPEPNHKWLKMVLSKRNEGQLIPRSETSPYFKEWRERVSQMDLSSGAAAALIEFVDYGTLEEPNKSPTFAMELFITGSKFQFPELELEVKNLLLRKPTSWFDAASLQVYCQGVNLDQHQDLQWRLAQVIITSTNENSCNVCDIDFTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N091</accession>
    <name>A0A1D2N091_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD repeat-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07993</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000335">
        <property type="protein sequence ID" value="ODM98689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N091"/>
    <dbReference type="OMA" id="KQMPPRI"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049916">
        <property type="entry name" value="WDR72-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099:SF4">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="534"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="641"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1188"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM98689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1581" mass="174287" checksum="20BD797D2FBA6829" modified="2016-11-30" version="1">MSQTSSLVIPIVLWGKDAPSHPISSLAISPDLQSIVTGCNDGQIIIWDIQHQESKLPAGGGDLGDSGEVSPQVLLETSPWEMTPRCFLIGHSGPILSLAFVHLTTDNFDLIISSSDNGELCNWDAIDGRCLESSKCLNPHTKMQPYTLAFNPLEPKLFCTGYYPDIHIIDPVTLETLICLSSHVNPDWVSALHVLRPNKKLDDVILATTISGTVKVWTVNEQEFREKTPLYENESKTIRTKNVSTLVCCLFNNRTVLIVADKVWQIYDAGDFSVLTQCTPKNKSETWIGGDFIAPEKVVIFGSSGKAYLFKLPNNCIVDHKDFHRIGFKDEPFNYCVFNVPNSKNLVAPPCFNVLSLGMEPPSTRKPSKFILIRGDHESKVVVWSIPDVTNSQISQLKQMAFGEHSAESEDTKKTLNPNFTPPEVPPKSISSLQQAWDNLKPSPPGILDQFVSTIDDKIIIESFFNLKDAINADTDECHGPLLTCSIFIPQQSRLVCGREDGSIVVVPATHAIMLHLLHGRHQQYEEWPLHQILLGHKGKVNCLVYPHGVHPRYDPAYLVSGGRDFSVILWDIVKCDLLYRFCCHAGEITQILVPPNDCSFNLIHYMRYPQARVLQTVCSISTDHSAALLSLREKKCVLLASRHLFPITSIKWRPLDDFLIIGCADGTVHVWQMETGHLDRVLYGMAAEDVLLACDENGNLTAMQETGLANPAVHFFRGLKSRNLAAIRHAAQRGLNQLHQPGQHGPANDPLDHSRTRLPPLVVQGLRTNDTDPEAHVLFFDVEALIVQLLSDEYGALSPCTLEAQGLIGQTEYCKIVTLTHSSSPDAQKKIADFFGKVKDRAGDMEKILKDKDKHGLFAKVKEGAEKIQAKAESALLIKQEKESASHSTASLAGLGSEGSGSGSRRNRNLLFESSIPMEIAQLLISLLLGWGLDQELDSICEARLGLLKPLVPICFGQISRGGYMSLMSPTWKPSTRSKLEEALKFQSSLSQRVKWFTSRTHWEVSCSLTTNHLLAIVALANTLMSMQNATFVAEQERIRKANRPSTKGTGNLLPQSDDGYITQQAASKHGWSLVATLHCVMLHEKLKHSICYKEPLVETLALRWQDRCVEVRDAAQALLLAELSRIGVEGRKRLVDLWGPYLPNLNVDPFSTNVNVTPVGQQVTPVTTPSSQGELVADDQASVVGGTTANSEQDFDEDVDEPSLKPSPSEHKRKQTTAIILLGVLGAEFGQEITARSMDSGRNKGVEGFGVGNSNLARLTSKALSHLLLNPQQNQALGGKVMVAPTGPFSPLRRAAIDLIGRGFTVWEPFLDVSKVLLALLELCCEADNLVPSMSFGLPLTPQADACRTARHALTLIATARPAAFITTMAKEVARYNTLQQNAQAIQINLSNIILNRSKPEILRVIELLIEKMQSEISDLIVEVMDIVLHCVDHGHLKTRGLGEVFPVLCRFSQVTHCPTTRRIAVGSRQGHLAIYELRSSKCQTIPAHASPITACAFSPDGKFLASYSCTENKMSFWQQSSSGMFGLGHTQTRCVKTISTVPLPDNLKNTIRSPRLVWTGSRNVSLLLADGSENRYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N361</accession>
    <name>A0A1D2N361_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc metalloproteinase-disintegrin-like BjussuMP-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_06959</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000259">
        <property type="protein sequence ID" value="ODM99716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N361"/>
    <dbReference type="STRING" id="48709.A0A1D2N361"/>
    <dbReference type="OrthoDB" id="5951731at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0401">Integrin</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="5">
        <location>
            <begin position="68"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM99716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="161" mass="18095" checksum="7E663685842C8719" modified="2016-11-30" version="1">MQSHGDHHDHQSSFNNILGITNDLLTSHPFKTKDSKLSDAGSAPHLHRVKRGSNDDTRVPYNSNAKSRYVEVVIVVDNKKYKELGADIKAVRRRSKDIAGIVNALYAPLNIFIALVGMVVWTESDEIVIKPNGDDTLASFLHYRKERLLKEHPNDNAQLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4I6</accession>
    <name>A0A1D2N4I6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000228">
        <property type="protein sequence ID" value="ODN00180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4I6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="88" mass="9238" checksum="5DA146B8E013FF5D" modified="2016-11-30" version="1">MASSLNGDTCSSTMSSSSSGSVSDLFQTPTEALSSVSLGSDKDQPSELGNGTPGPLGMPPKSDKRRTFRATTVEMDTTCEDKLKDCQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N556</accession>
    <name>A0A1D2N556_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="11">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_06485</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
            <location evidence="2 11">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The WWE domain mediates non-covalent poly(ADP-ribose)-binding.</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Ubiquitinated; autoubiquitinated.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01000225">
        <property type="protein sequence ID" value="ODN00195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N556"/>
    <dbReference type="STRING" id="48709.A0A1D2N556"/>
    <dbReference type="OrthoDB" id="8251605at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072572">
        <property type="term" value="F:poly-ADP-D-ribose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16546">
        <property type="entry name" value="RING-HC_RNF146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044110">
        <property type="entry name" value="RING-HC_RNF146"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033509">
        <property type="entry name" value="RNF146"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018123">
        <property type="entry name" value="WWE-dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004170">
        <property type="entry name" value="WWE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037197">
        <property type="entry name" value="WWE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13417">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13417:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02825">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00678">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117839">
        <property type="entry name" value="WWE domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50918">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0879">Wnt signaling pathway</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="128"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="WWE" evidence="14">
        <location>
            <begin position="185"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="274"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="613"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="862"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="361"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="613"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN00195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1178" mass="131176" checksum="CCADDD523DB733E5" modified="2016-11-30" version="1">MYILKKNAADLAAEPEQLTITPTYAYAEVMQYLQLKTKDNGRTDILCLIETSVIYVRIRCKDLTGGVLRWKLPHTVRFGFNYTVLVEEAEMAGVPDENTTTGGKDADESSADAGAAGCSQDSNGGLECPICLQPCMHPVELPCHHVFCFLCIKGVAMQGPQSRCAICRAQIPYSVLTNPHLKDVSQLTKEPKVANGYQWYYESRSGGWWQYDERTMQDLEKAFSNKLLTCQLLLAGHIYVVDFTQMIQYRSNNRNVSRRIKRGINLEKRGVAGIRISGNNSGDGSNGGANNDSSPPPPPSSTGPSSGRRRRGNFSAPGNAQAANTPGNVQTSGVTSVQSNPAHPNLGNPSDPSSQDVLVSDSDDESVDEDEDYDSDYSEGVDADDDMELGEEEEALIGDDSEDTEDDDEYDTRDGARAPTSRSDRSNSSNNQTPPPPAGAGPANVRIPTVVEAVVQKVVEVVVVEEDPIMETVAQPAAQPPWITSQLLHPPSHLQVPMCNLEDVAKVSNNNNIYIDSQIIGQYSHSVTLRPQYEIWKFTGFRWQYSTYFLKYFEVSYSVKVMITYDVRFCFEAGGSLDGHIHSSAPVSTPNYAFFINFFSILLKMAQVQEQDPKKVRSTKRVQEQENSEEKEKEKKQDGCDVNAEIPPGIDNPLPEYGELSKQRHIKKANESVSGGEDPQQKKREACREKPIKKGCIPKDIILPFSEDKPDTLGRFLETDSQTAIGAGNLMKGVRVRKDKVEFPGWCIELTDPQLQSVQDAKEILSSGKPLCDMLDELIEAIGGLGSGITDTDVIETLRRIPHTSKGWSFSHFMFIAGDPKFAKKKGVLQDPLPVQFTECLEQSGDSDKKSKKKNVVDRLYQLPQTAPPDPWPPADAKKEEKDESGFSQRAKLFYSGLLYCDMYDTMQALEKVYLKGESVPEPRESALKRQQESGFGASDMGTRKLGFAEWDRPLPPLPKVSPYLADLPLVGKRRKILKPNGDVGMYRRSQTSLHPIFLAVKAPREAKATIKILEDGQRVKSILSLMASQGGNCLALLPDIGKILHMSDTLLHNQEVVTVQKGPKAPKIYKGNDMIWILKEGKNLFRPHGLPPQIAKIPPLIAFSDGLKLREICKQVRDQHWSYICLRKNQFRESVWQLMHVERIPCGNLRESFAYSFQTYLPPKSVFPIIREDALPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5G8</accession>
    <name>A0A1D2N5G8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Aminopeptidase</fullName>
            <ecNumber evidence="18">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_06171</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="16 18">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16 18">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="18"/>
    <dbReference type="EMBL" id="LJIJ01000202">
        <property type="protein sequence ID" value="ODN00507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5G8"/>
    <dbReference type="STRING" id="48709.A0A1D2N5G8"/>
    <dbReference type="OMA" id="NGVCIRN"/>
    <dbReference type="OrthoDB" id="6750768at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000003">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000005">
        <property type="entry name" value="Aminopeptidase N-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000001">
        <property type="entry name" value="Leucyl-cystinyl aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000006">
        <property type="entry name" value="Puromycin-sensitive aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF299">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 18 22" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 18" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 18" id="KW-0645">Protease</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9 16 18" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="21">
        <location>
            <begin position="107"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="19">
        <location>
            <begin position="337"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="20">
        <location>
            <begin position="636"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="17">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODN00507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="990" mass="113768" checksum="8C32FAAC5BAC8C1C" modified="2016-11-30" version="1">MKHLSPMTCGTGEASNVNKRTLYEQDRIAVCSQKRAVGIALLVFVGLFFVAVIIAFATPLSGCSFLNGSIDTEPLTDEELLEHNRFILPSGEEFPWNKSRLPDFVRPLHYTIQIHPNLTTLDVTGWVVIQFIVLNETDFIVFHSRNLRVIDKWVKEEVEDPHRVEPHNISRLLEYPPFQQMYLELAEGSKLVPGKNYSLGIRFYTNISTELEGFYLSSYVNSQGERRYLATTHFEPTYARSAFPCFDEPQFKATFKMIIIRNQQHKSLFNMPIKKIETVYYGYHMELWRDEFEESVEMSTYLVAFVICDYESISNKTTKGVEVAIHTPPGLLPQASFALQSAIQVMEYYDEFFGVPYPLPKQDLIAIPDFGAGAMENFGLITYRETSILYDSNESSSAAHQWVAVVLAHELAHQWFGNLVTMKWWNDLWLNEGFASFIEYVGVDHIRPEWKMMEQFVIEKTQPALALDALGSSHPISVEVQDPREIEAIFDTISYNKGAAILRMLESVLGLNVLRHGLTDYLNEHKFDNADTKDLWDALSTSTNETMKVKTVMDTWTLQMGYPLIEVRCENNTVKATQERFLLNPADNETGVELIQSPFKYKWYVPLTYVTDAKPRTMQLVWMNMNEFTMPYRAEWIKFNVNQTGFYRVHYQGKLWDSLVKTLLSNPFVLSPTDRASLIDDAFTLCKAGVVDASVPLEIAKYLMKETDYVPWATALEHFRSWSKILYERQAHRLLMQFVLKLIEPIYKRVGWADEGSHLMKVHLLLSYSSSSLHTIRLLRSEILSTAILCDNKEAVKEATTKFNNWMQKGARVPPNLREVVYSAGIKYGGVVGWDHCWAQYNASRIPSEKKLLLKAMGSAADPWLLQQYLDACLSRDVVRPQDVRTVLAVVASNPSGRLLAWRHLRAYWMNFQNLFGEGSFTMGSLITAVVSHFSSEFDYVEVTNFFSDVDVGSGARALNQSLEMIRLNIRWLQNNENQIEDWLRKYLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N640</accession>
    <name>A0A1D2N640_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_06263</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000207">
        <property type="protein sequence ID" value="ODN00426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N640"/>
    <dbReference type="STRING" id="48709.A0A1D2N640"/>
    <dbReference type="OMA" id="QPPHDVI"/>
    <dbReference type="OrthoDB" id="1478556at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="7">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN00426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="165" mass="17569" checksum="B11A8BC71404675E" modified="2016-11-30" version="1">MGPKFDPSEVKIVHLRCVGGEVGATSSLAPKIGPLGLSPKKVGDDIAKATGDWKGLKITVRLTIQNRQATISVVPSAASLIIKALKEPPRDRKKVKNVKHSGNITYNDVLNIARTMKERSMAKKLVGTVKEILGTAQSVGCTIDGRAPHDVIDAINEGTQQVPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N642</accession>
    <name>A0A1D2N642_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000192">
        <property type="protein sequence ID" value="ODN00692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N642"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="757" mass="83443" checksum="415A031B26E03A84" modified="2016-11-30" version="1">MSHLLEEDSDSNTRSSEIDENDCESVDTDSLHLEEMEEDEASGLALEMNPSERVIGGSIILQIDQTNGRNGVHESGNNSFRFLQTPFENLTQSNTNEGVPTSSILSSLPEDERGLQLHHTASASTSLSEAASDNMSTRAVMGDTPSVVNTVPGEDDIDNSSQASMADSDADRVRRIHNSIFRGLEHDLAELVRIREETIQFLENGTQNSNDANENSGFDDELTPSNPNEDEFSSNFDEINNNSDGSNTVLPSTEERPAPVIIRERLTFPTRERLRVGFDSKGRGNAETDKNPNTLTFDGYSYTPIAKFDNAPPAKPGKPYVEVGLMNCDEKAAAARKIFDKLQYGDPDDESACFVRRFWRETSTVMENTSQEDQLPVTVDAATLAQRSASLQATLEEAFGGLRLRLQQAQAEASANLQSIQRENNGEDGSNVGESANLETGENGNENSSENTPQNDPAATAAAQSLSYYQSWDEETSIMNNPLNYDIWNELEDSNDVGSTITARINLAERRANNNSGSAPSRSCLNRPPSSLVRTTTVAVGTDENSAHDGDLEDEVDDEISSYFHNQLANSMSLSSSRGRCEEHLNRSSSRDRDFSPGTREFFQDIGVSEQLGRDIFDMFNISEEDEEVPQLIRDNAGPEVNSQMPQPLYRRRRGANTEHGDELDDDDDDDEDNLQVDFPGMDSGSDGDEEDEDDGQPPVIPRVPLADMTSGSASSLFAPNMEDDCSTRVYFDESYLSFAHASRDTQEDEQEDDDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6A7</accession>
    <name>A0A1D2N6A7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_05892</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000186">
        <property type="protein sequence ID" value="ODN00803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6A7"/>
    <dbReference type="STRING" id="48709.A0A1D2N6A7"/>
    <dbReference type="OMA" id="DERSADN"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16667">
        <property type="entry name" value="RING-H2_RNF126-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000069">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF243">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="234"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="83"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="283"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN00803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="329" mass="35185" checksum="DA81D8298242B08D" modified="2016-11-30" version="1">MAEAGVDVQTNTGRFFCHKCNEELAHVLEDFTCPKCKGGFVEKLSDIPPSAAHGGGNTSPGHGMNHFQEGIPFLELIRGITSSMEVPPPSGQSSRSGGTGSGARSPDMNFSFVMDMRPRNNSQPGGGAAGGSQATAGQNAQQPYNPMENMLFSFLNDLITGLSGGGGGVTVGGGFPMLANLGDYVWGRDGLDAIVTQLMNQMEGTGPPPMPTDKLDRIPSVRISQEQVDRKLQCSVCWDDFQLNDEVKQLECDHVFHPDCIVPWLKLHGTCPICRKDLTNTDDASAAPSARFEPPGQDNSRSDDSLGGSSRGGQGRSNNDLDRMDFEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6U1</accession>
    <name>A0A1D2N6U1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Krueppel-like factor 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_05702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000178">
        <property type="protein sequence ID" value="ODN00978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6U1"/>
    <dbReference type="STRING" id="48709.A0A1D2N6U1"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000007">
        <property type="entry name" value="Basic krueppel-like factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="355" mass="39842" checksum="BA4CC6E5A69E4A00" modified="2016-11-30" version="1">MTFLSRGVARHNPCWFEIILCDYCSNCGSYITDSFQNSESPFSNTSDSMEFPGGTSAGSFSDFTSDPFSPYTTALPSVEAADLLTDNFSTQTSTTLNPTLSEQASITSDVSSIFEGAPLLDELGSTGYEDLDMCTTTSWESMLSFSADPITASIPPQDMTNWFSNVEPKMIECSKMPTAILPIINPEPTSILPHLPPPPSFGLEMKPDIEKVNIPTLPKRTRGRKPGSCNKNKGPVKKPPQEKGRRRGKTLSEVLELKCPWNDCNKVYFKSSHLKAHLRRHTGEKPFICPWEECPWKFSRSDELGRHFRCHTGDKPYQCTVCSKRFARSDHLSKHKKVHDRSREQCEFLFNTLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N769</accession>
    <name>A0A1D2N769_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1</fullName>
            <ecNumber evidence="1">2.1.1.57</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cap1 2'O-ribose methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67020"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="Rhea" id="RHEA-COMP:17168"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167609"/>
            <dbReference type="EC" id="2.1.1.57"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.57" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000170">
        <property type="protein sequence ID" value="ODN01113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N769"/>
    <dbReference type="OMA" id="DAKICEN"/>
    <dbReference type="OrthoDB" id="429597at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004483">
        <property type="term" value="F:methyltransferase cap1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050851">
        <property type="entry name" value="mRNA_Cap_2O-Ribose_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16121:SF0">
        <property type="entry name" value="CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16121">
        <property type="entry name" value="CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="3">
        <location>
            <begin position="362"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="868" mass="98648" checksum="35B2DEA427B33F4C" modified="2016-11-30" version="1">MADVEVMDVNVESIPGTKNPLAANSDDNELIEELEEVSEKHSNNGHTGESHDEDKNCHATNSEAATCKLVPEIGNKKDCEALGELNVVENVVTPRTSMVPKKSNLKRPKCNVNGVSPSATPSKRIRIVENLDASNCNNYIKLDGDLETDTIECADETASVTEEESCGEKMVWLNSPSSHVNQSAINVDFVRDNLSPVKRNFSVEIDMRFILTETVTAILSTKTKIANVGPSDFHLWISRNSSHSSKPKCFLYQENFLRMANLDALLHYDLTSPKELVNSTDFEKIYYVGDLWHNSKGFREYILWATNQHQARFSTKILAMKTIGPRSTEKIIRDKAGILFHERTPLKTDTDDLKHLCSEMVESCGRFAEPEDILMVDTINHYVDFVLTRSYGKGLHTFMVDNPEVSYAYESCREVRYQKYFYVECLIALRCLREGGTFICKIFDSFTLFTTGLLFLLYKSFRSISIHKPSSSPTCTSERFIICTGKIDNADTVYIVDFLSDCLDMVVNNQEQRKIVRRRVRRRLAVLRMEVQTLIPLRIILSHAEFFQFIRQSNIRLTTQLVESIDKLCELMGSEGMISNDKVATLLGAPNFSLSSLQNIPSVLKYQEDLNVVPVEACKKFLARYNIREGMFDLKEKRIEGIDLLLPMVGTCHGNKNLLAFPIQSRYAAGINKPVQGFFFGCGGADLLHFEGNSWRQLDCPEFCLPYGTIVLGEIAEEVSVSGKSYNFVRRFHLFDAVFIGGVYIGSFTFEIRQRILARFIHCLENSSSNLNQNICMVKSSALNDVPDFYNNECICKEHNYVGYNSKLRRYMRNKQPACDNENWAFVGGFLVVENFEDMSPEIFFNNHQCSWSIWVMDETKTISELTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7D5</accession>
    <name>A0A1D2N7D5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cholinesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_05521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000168">
        <property type="protein sequence ID" value="ODN01180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7D5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="38"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN01180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="187" mass="22147" checksum="882815894D348804" modified="2016-11-30" version="1">MMMGPKRPKRSLHMTLNTPWDDAYYLFHPIQEQDNFTSYSQRHELSEEDKKVTDALVKIWVSFAKYNQPKQAMTELPDYGRWTRMEPGHKSLNYFLLSDHPLQRGMRSDFRKAECQFWMGTVPQVRNLSKTIQELEPFPILFWCSVAIVILFALIICTLIVLILWSKHRQGSYGRGDNIYLHHARQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N864</accession>
    <name>A0A1D2N864_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-L-arabinobiosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000152">
        <property type="protein sequence ID" value="ODN01442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N864"/>
    <dbReference type="STRING" id="48709.A0A1D2N864"/>
    <dbReference type="OrthoDB" id="8248091at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005194">
        <property type="entry name" value="Glyco_hydro_65_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054491">
        <property type="entry name" value="MGH1-like_GH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22633">
        <property type="entry name" value="F5_F8_type_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03633">
        <property type="entry name" value="Glyco_hydro_65C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22422">
        <property type="entry name" value="MGH1-like_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannosylglycerate hydrolase MGH1-like glycoside hydrolase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 C-terminal" evidence="1">
        <location>
            <begin position="250"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="620" mass="70198" checksum="24311071B7EDED76" modified="2016-11-30" version="1">MDAMEYSASSLPTDDPFGGGVGYRPSFNSEMYANAIAISKIARMNNDVRTAEEFERRAALIRQGILDHLWNDQRTFFFHMFREDNPNNELLDSREEIGFFPWRFGVPPQEDSKYDQAWEHLFDPQGFNSTYGPTTCEQRSPWFDGNQTAQCCWWNGNSWPYSTGHVINSLAALIKNYGAKNVVNVNTFLEVLHKYAETQYKNDKPYVAECHSPYRKLWVCDSFNHSEHYAHSTYIDNVLGDLLGIEPQSDNTFVISPLIPSSWSYFIVENLAYHGHNITVLYDSDGTRYNTGAGMKIYLNGELAASQPELGRMSLNIPPPNVDESYARKKVENYAANANSFGYPMPNASYSSDYSSTWQAVDGRIFYDSVPSNRWTNWNSPNQVDWFSVDFGPGRSKTLDQIKVYVYSDVVTGQGEVDCPTNMVVEFLNSSGDWEQAQNQVSTPSTCIPNDVMTIEFDPVKTQKVRIVFSRSTFYFVGITEVEIWAPWPQVLEEGTYEAEDGYITRANMLAADTASGGSYVGQIDAPDASVEFTGIWVEEEKEYDVRVYYSNGIQEQATMTVSANNVHSQVATFPPTVNGWGQFDDTFVTVRLPLLRGNNALICKHGENFVELDKILVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N932</accession>
    <name>A0A1D2N932_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000139">
        <property type="protein sequence ID" value="ODN01761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N932"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="164" mass="18236" checksum="7235CED904D0A68F" modified="2016-11-30" version="1" fragment="single">ITGYPQTVGVGVIQNNHWLDKIPSVEVKFKPDGITVRTGPSREDIYWIIGYIVLGIILFLLVSLAVGFCIYCICWRDQQRGSRVIVREMPVTGSSVPFSFRGSNPNMGIPQASTNMPRTHNEILIRDCLRSQAKNSSGSRSKSVNPIGTNTSHHTPPPPYRSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N981</accession>
    <name>A0A1D2N981_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EF-hand calcium-binding domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000138">
        <property type="protein sequence ID" value="ODN01811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N981"/>
    <dbReference type="STRING" id="48709.A0A1D2N981"/>
    <dbReference type="OrthoDB" id="10260307at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043226">
        <property type="term" value="C:organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46763">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46763:SF1">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="25129" checksum="C5E0D8BE81C364BC" modified="2016-11-30" version="1">MERAMDRERGMEPQEDLGDEDEGDFEGGDDVDEEENYHTVKAANAADLLEYVGNAYTFSPDPFQADIERRVALMFQIFDTSHQRLVDVREVGTMVRSLDLCPTEAEVQEIIGHVEESTTKGVVKLETFVKHISFVIMEGTKYRQRTKEEMMRFFYKLDKEKKGVVDPDRVKAQICKDGEPFTFEEADEMISFAMDKDDGLIHYEQYVDTIVAALSISIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAL4</accession>
    <name>A0A1D2NAL4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase subunit 7C, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytochrome c oxidase polypeptide VIIc</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_04375</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase VIIc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAL4"/>
    <dbReference type="STRING" id="48709.A0A1D2NAL4"/>
    <dbReference type="OMA" id="FLVLRYH"/>
    <dbReference type="OrthoDB" id="2392202at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.49.10:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit 7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.49.10">
        <property type="entry name" value="Cytochrome c oxidase subunit VIIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004202">
        <property type="entry name" value="COX7C/Cox8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036636">
        <property type="entry name" value="COX7C/Cox8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT VIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02935">
        <property type="entry name" value="COX7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81427">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN02293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="80" mass="9132" checksum="8E77FD517E747D40" modified="2016-11-30" version="1">MFRNQLVGRLMFWRQQRRNITTTRPKRGGDHHDEGGVPGATLPFDTSNRYLLALTVGTFFGSAFATPFLLLRHQLKKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAM2</accession>
    <name>A0A1D2NAM2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">Ocin01_04389</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="21">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NAM2"/>
    <dbReference type="OMA" id="YCFLAFN"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030832">
        <property type="term" value="P:regulation of actin filament length"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000421">
        <property type="entry name" value="Serine/threonine-protein kinase PAK 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052409">
        <property type="entry name" value="Myosin-III_kinase_activity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46256">
        <property type="entry name" value="AGAP011099-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46256:SF3">
        <property type="entry name" value="MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 21" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="12 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0966">Cell projection</keyword>
    <keyword evidence="22" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="14 21" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13 21" id="KW-0518">Myosin</keyword>
    <keyword evidence="10 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="18" id="KW-0844">Vision</keyword>
    <feature type="domain" description="Protein kinase" evidence="24">
        <location>
            <begin position="20"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="25">
        <location>
            <begin position="352"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="21">
        <location>
            <begin position="926"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1095"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1291"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1381"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="22">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="1321"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="445"/>
            <end position="452"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="ODN02300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1405" mass="160705" checksum="B6AA23C1ED948826" modified="2016-11-30" version="1">MELNSEKIRFEDLPSPGDKFQLLDIIGEGTYGEVYAAIDVELEATHDSSDKTKDAKVAIKILENLPENMEEAEEELLVLRDYSIHPNLPSFYGLYFKRAARPEDCQLWYVMELCSGGSVTDLAQGLRKFEGRRLTEFQIAYILREVVDALIHLHTHHCIHRDVKGHNILLTGEGRVKLVDFGVAARLKDTYARRNTSIGTPYWMSPEVIACERQIDSSYDVRCDVWSLGITAIELAEAEPPLADLHPMRALFQIPRNPPPTLSKPHDWSSEFNDFVAECLIKDMDQRPFMVELRQHPFLQQLTRIPEDIITNDMVRDIQMVKAHGDLVKREPEVTTKHGKLKTDRKSKLQTMFVDDLVALASLDEETILDQLFHRFQQKQPYTYIGDILIAVNPYEDLGIYNEFYQFKYRAANTADIAPHIYSVADQAYHAMLHQKRSQNIVISGESGAGKTESAKFLLQHFVYLGKAPNRNLESKILHVNPIMEAFGNAATGMNQNSSRFAKYLDVTFTRTGKITGAKIAVYLLEESRVDRQAQDERNFHIFYYLLHGLQSKGRRQEFKLDKRRYSYLQGIDDSADTQQENVEHFEAVNDGFYLLGFRMEEIESIYKILAAILHLGEIRFDAGTEEDGCSIKNMDELETVANLLGVSAGDLGLCLTTRSVVTAGETFIRRNSSAEARTSRDSLARGLYNRIFRWIVYQINALLGISRLAYGDPVSIGLLDIFGFEAFQVNSLEQLCINITNEQLQFLFNQHVFTWEQQEYMAEGINIEVVQYADNRPILELCLGKPLGILSLTDEESRFPQANDWTLLEKLNANLQTNEFYFPPKSNADLTFQVRHYAGKVTYSAKGFVEKNRSNHSSEIIQTLRKSTNNLVKAIYKCLLTRTGDLYVISRRDSIAEQMQKEEELGLASQTRSHMTIATSFRFSLMDLMSKLLGGELHFVRCIKPNDFGVPEQFDHIKVLRQLRYSGVLETIRIRQLGFSHRFTFAEFLKSYCFLAFNFDERVVADKDSCRLLLLRLKLDNWALGKTKVFLKYYHVEYLAKLCEQQIRSVIFVQACVRRWLAKIRFRKGMWQVAKTIISTQRAAKLWLNRKRSADATANEPGGPSKSKRGSALRSRLMGEEILVDDDDMSTEEKAAILIQSHFRGFLVRKQWGPILEERVKQIVLSNAKREDAEKALRDEGLNEEDAALVLQRFYRKWKVTREKSQDEDEPPPEPRVKLDNWDAPFRLMECHMKDLRAGRVRTDSVNILPEQRKLSKFGQQLLGNALEKKVHELRRPSREKSERALDIRAALEATPKPPVFSKDSPGDPIAATTKPDPPVISRRSSPPSKVEAATSPEPPPIVARKPPPKEGMKATPKPQGVVKKYLAECEQSSMGDFRKNLKKAAHRPTDSLKKGWNSQDVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAT2</accession>
    <name>A0A1D2NAT2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">C-X-C chemokine receptor type 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_04316</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000114">
        <property type="protein sequence ID" value="ODN02364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAT2"/>
    <dbReference type="STRING" id="48709.A0A1D2NAT2"/>
    <dbReference type="OMA" id="CESASKF"/>
    <dbReference type="OrthoDB" id="10690317at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22752">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="32"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="491"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="500"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="606" mass="68049" checksum="5471AEDA5E481ED5" modified="2016-11-30" version="1">METYTIFENVVDIPILGLLVTLGVIFSIGLIINIPAIVIYCRSRQIRSFTDKFILFVVISDIVSLCVLIPTSFLFLLESYDNSNVAIVKKPEAEPLTLEEHPFFLESDIFNSKVGDEVEAEAINSSSVCIQQWIYIVHKFMLIMTANLSVLAALKIAVERYLAVVTPLHYHKVLKSTVVIVVSLISFLLATASAVIMTWGANPDGLYESLRVCESASKFLGGSWSSRDTLAAQSMAKFSNVELKESDSVLSSLPQHDLSNESLNGNTSSTWYLWPVLKLAHATVFFIVPVFVMMFMYIRIWTEASKQNARLAHHSKNPYIFPVDMKKPERLNVDGLQVIFSRFKLMQRLRRRARMDRAARVAFLTIGLIIMCFGPLYYVQIASAIYSLTMTEAVQSAPKSFSKLLLFLPTILACCHPLLSPVVYVYRYKKVRSELTLLLNKLISSMNCCNNGSTDCQDIVHQFNNLAQKLPASPSVDVVINMLESQAMSNTNSDTTLSVNSRNTNTDNLSSDSSGLTEKAYPISSIFCDDKQQLSTEGSETDLESQEYHEQRVISEETRSGLFHLISCWVGSYSRRWNRHRESVTSTASFVTLLSNRNRSIPSVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB07</accession>
    <name>A0A1D2NB07_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_04266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000112">
        <property type="protein sequence ID" value="ODN02433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB07"/>
    <dbReference type="OMA" id="ENVPKMT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="425"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="474" mass="51762" checksum="DC93D910A7956D61" modified="2016-11-30" version="1" fragment="single">MEDKGTSNSGNEPKKIVALKVPSLFIKSVPSGGGESESAKDESAPKKVNRPMPMSIRKKLEESKKNEEKAAERTDDSKSESSNGSESSLPKKTSTPRSVPRAMPASRKILEQNKSSESTESANPVVNKEVKKPMPASIKRKLEEKANSDNKESSGSDISSVSKNSSTTEKTTSSIRRKLDETKADEKLVVDDDDDKVSTTSGKGDRVSSIGSTTSSTTAKVSRPMPASRKLQMEKESLEKNEKLPQPDENVPKMTATPKLIINKPGPASVKRKAEESITMGGSESKQKDGGKAETPKKPQPMPASARRKLEEQSKTNSDANETEKNVDSDVSTKPANKITISLDGIKFPKFSKPGPASAKRKAEEQKQTTTKDKDDLNTSEQFQTSINDDQNSDGADESKEGSRTRTRRSGSSLKMLTSLFTEKFPCQFCGQEFYRLGDKTRHEKSSHTDKKEKGPNDLKDSKKKSSKPPKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCI7</accession>
    <name>A0A1D2NCI7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_03885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCI7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN02795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="115" mass="12602" checksum="37B20CE4C9344366" modified="2016-11-30" version="1" fragment="single">MDGKREIYFGSTNTSTFGTVSVSFECETNEACTAFLVITGDQDIISEEELVSVEISTSSLKNVIDWSEPNSQIQPFHIYAKISKSDDSEVVNIIGIVCPVKGDINDCQTIPMVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND77</accession>
    <name>A0A1D2ND77_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kunitz-type serine protease inhibitor bitisilin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_03450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000082">
        <property type="protein sequence ID" value="ODN03213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND77"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF376">
        <property type="entry name" value="SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1203">Blood coagulation cascade inhibiting toxin</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1199">Hemostasis impairing toxin</keyword>
    <keyword evidence="3" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905386" evidence="8">
        <location>
            <begin position="28"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="9">
        <location>
            <begin position="34"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="89" mass="9781" checksum="725CFF4DB2F1CE73" modified="2016-11-30" version="1">MSKSSKISIAIAMLAISTLFSINTASAESDIDPCTLPKDQGDETSWVRGGHYYYNSESKQCEFLDWKGGSSNANNFKTKEDCEQACVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDQ4</accession>
    <name>A0A1D2NDQ4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heat shock protein 83</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_03290</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000076">
        <property type="protein sequence ID" value="ODN03383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDQ4"/>
    <dbReference type="STRING" id="48709.A0A1D2NDQ4"/>
    <dbReference type="OMA" id="CYMWESS"/>
    <dbReference type="OrthoDB" id="5426351at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000001">
        <property type="entry name" value="Heat shock protein HSP 90-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="11">
        <location>
            <begin position="112"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="298"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="768"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="205"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="800" mass="92295" checksum="96A468AF7683CB83" modified="2016-11-30" version="1">MQEGQMAKDLCPEFKNYVLFTLEKVKISLDLTSDSDLLRVKCERNGFDERNRRRHELLSYGSRETVKILSISLRTIAFKMPETMETENVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDASKLESGKDLNIRIIPNKDERTLTLIDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVTVTSKHNDDEQYVWESSAGGSFTIRTDTTGETLGRGTKIVLHLKEDQAEYSEEKKIKEVVKKHSQFIGYPIKLLVEKEREKEVEEEEEEEKKEGDEEKKEEEDKPKVEDVGEDDDEDKDKDTKKKTKKIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLACKHFSVEGQLEFRALLFIPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEDLIPEYLNFVRGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMDLMEEIAEDKDNFKKYYEQFSKNLKLGIHEDTANRKKLSELLRYHTSASGDEMCSFKEYVSRMKESQKHIYYITGESRDTVANSAFVERVKKRGFEVIYMTEPIDEYVVQQLKEFDGKTLVSVTKEGLELPEDEDEKKKFEESKAKFEGLCKVMKDILDKKVEKVVVSNRLVDSPCCIVTSQYGWTANMERIMKAQALRDSSTMGYMAAKKHLEINPDHPIVENLRQKSDADKNDKSVKDLVMLLFETSLLSSGFSLEDPMVHAGRIHRMIKLGLGIDDDEPTHVEEPTAETVPPLEGEAEDASRMEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE39</accession>
    <name>A0A1D2NE39_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NF-kappa-B-activating protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NKAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE39"/>
    <dbReference type="STRING" id="48709.A0A1D2NE39"/>
    <dbReference type="OMA" id="HGKQWGD"/>
    <dbReference type="OrthoDB" id="273141at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040466">
        <property type="entry name" value="NKAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009269">
        <property type="entry name" value="NKAP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087">
        <property type="entry name" value="NF-KAPPA B ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087:SF0">
        <property type="entry name" value="NFKB ACTIVATING PROTEIN LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06047">
        <property type="entry name" value="Nkap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NF-kappa-B-activating protein C-terminal" evidence="3">
        <location>
            <begin position="252"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="362" mass="40969" checksum="FC5CD4B404A4C8F6" modified="2016-11-30" version="1">MYMNHWKNTAALRPTFVEHRRQLREQICETGVPDVWNGSPSRIPADSDADSDYAEPSYNFSWKLKSGKQDSEKRSKKKKRKKSRSPSTDSSSDGELSDSDSDSDSDRGRSKKKKRKKSKKASKKVKSHKKSKKHKKEKKSKSKSKKEPEISSKDRKEADKLVRNIVADVKSKSKHDGSSSDSDSSSGEDEMWIEKCKPKSSPLNYGDSMITNFVSNILATIIDADESSKNADNEEEECIGPQPKQIVQLSVKEYGKALLPGEGAAMAAYVAEGKRIPRRGEIGLTSNEIETFEDVGYVMSGSRHRRMEAVRIRKENQIYSADEKRALAMFSKEERQKRENKILSQFRDVVQRKITAKRDPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEM9</accession>
    <name>A0A1D2NEM9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000065">
        <property type="protein sequence ID" value="ODN03720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEM9"/>
    <dbReference type="STRING" id="48709.A0A1D2NEM9"/>
    <dbReference type="OMA" id="VDRNCPS"/>
    <dbReference type="OrthoDB" id="5863628at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040010">
        <property type="entry name" value="ZN608/ZN609"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21564">
        <property type="entry name" value="BRAKELESS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21564:SF5">
        <property type="entry name" value="SCRIBBLER, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1110"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1240" mass="131861" checksum="852475D679648003" modified="2016-11-30" version="1">MKSGAVQDDNSTGGLGGGSTGSSSTSYRNHGALSINSATDLSTSSSSLLQGVAPSQPGSSGSSFGAPKETGKGGRNTTSSSSSMASTTQDVCVGTSVGTITEPDCLGPCEPGTSVTLEGIVWHETESGVLVVNVTWRGKTYVGTLIDCTKNDWAPPRFCDSPTSDLEMRTPKNRGKRGRAQTATPVNEPVVADTRSANAKLRNGAKGRRGSNTATAFVAPASPVKPDTWPKRKTRGSENESQEDCNPKNAKRPKVSKDGDRKERRSNSPAADNEKSGPSSPQLIECPEPNCSKKYKHINGLRYHQSHAHSNNFVAAEDSDSNMSTASNTNASAPADPVVTGNAGDATSEPMEVDGSPDVKDIIPAITANSSSAPNSNTDENSLSAPPTPGKKSSTTPPAPSKVDDKVYDLSMDSDLNPSKDLNSQTQDNPESYKSIKSNVAKSIAQAKESSNATSDQDSKLVPENLSKDSVSTPSTPSTTTTPTPITPRNTILTVPVVPYMSLQSARNMAHGHVVNVPQKLGGSSKDKDKNNADQAPSKKNKHKKKSKDKDKDRDGKSKGGDKDKHESNSKSHNVSLSGASDYSRSSGLFHNSNMGSDSAGSRSKDMNSDDNEGSRKNSTENRDDPQSPAYSDISDANDSGPDAELNVGSAIKDTCKGLVIPPDIKKDPIVPGVAGGPPLSFFNHGFYSPYLDTPSNAPNAASRQPKDVPPVVVEEPEKTRPVAPKHPNLPPNSQPPPPSSVGNEEARRSPKMDFHSKYPFPNYFSYPYSGYHNPYEHPSFGNTSLVSDNSFNAGGPVRGPYPGMEERERDKESSGPTGGDLRLGNQSKNSKPVEKDEGPGIVQIKQEPVEREERSGKERPQSSSHPLNMVEDKNIEIKSEFGSDHVEPKLMPPYMSNSNSKHMSKEHKRDREREERDRDRHERRHNSKDDSKSDNIKSGRNSSSNNEKNKGGSEESEPKERKDEGSKPTMETTGPPPPPTASAYYLPQSYLPGNPFGLPFDPSHPLYRNVIVPGQYPVNPYMHPGSMPRFQGGGPLSGGPSPLPEDLSRPNPAGPGNPSKALDLLQHHAAQYYSAHKIHELQERALKSPSPQVAANQRDRDGGPGGPGSNLTPTPSSPGGHPLSGGPGVNHPIGGRSSVGSTSVNNSAMPKPADLSKDAKPTIGPGGTILPGGPNSDNVRTPPPTQHHVHSHTHHHTHVGIGYPIIPTVPPQYSPHYGVLATSPAAPSVIPPFPSQKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFK8</accession>
    <name>A0A1D2NFK8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Paternally-expressed protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000064">
        <property type="protein sequence ID" value="ODN03756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NFK8"/>
    <dbReference type="OMA" id="DASCCED"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041940">
        <property type="entry name" value="choice_anch_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905490" evidence="2">
        <location>
            <begin position="30"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="315"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="921"/>
            <end position="1897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="934"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1482"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1510"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1537"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1565"/>
            <end position="1597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1606"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1689"/>
            <end position="1774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1781"/>
            <end position="1897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1923" mass="203591" checksum="C7C2F96EF8427786" modified="2016-11-30" version="1">MLKPSYQQHASVLLIVLSALLAGLNLCDAIRLNPDGGYDIVIGIEENTPEPLNSAAFLEEIKVGVEAFSLELWKTTKKRFFINSVDVLVPPNWWTVSRFERATWQTLLGSEIRITHNIPVPNVVNPNPCGTPGLYMELPDSFFKAVRGGQFGPAGKALVNMWARYRFGVWEEHGIPGDMKFPYFYTHPSLEPKWEATGCANEEITGSFLTVDGDISDRCDPHTASGPDDDCRFIPSSSNTANSSLLHFQWMESVTEFCDEKSHNYAAPNRHNLFCGHRSVWEVIKQSADYISTTTCTETVTLPKFTILKENSSPEFYILLDRGRTITPEKVLQEVMGAMVKFIGTPSLERVNIAVGTYPHANQGKNHYYVKEEIGWAPISSVIYELQSVLEDSSNTEGPVIRDFGLAIQEVAEKIKQRNHLAGTVILVIKRGATANFFDKLTFEQEVTASIKEDNRIKIFAIETQQGVQTPYTNLQSLVQDTAGQYHSINDTMNTARKLEKFLADMQEILEQSSIMNSASSWVTQKQYTEPHETIEIPIYDTVNLVRVHLTTSRQMLESEIYLEQISGEHTSVALINRAEWNENSDMSRRLVFSYLIRDPKPGSVWSLKHGCPGEQAIDCRFFLLVTAENARPPIWLQPIPGINSMSLFSSGAINIDVSTSAEYNYLDMSYHGVKIAPFAIFAKIEMNQQRVLGLENVNALIRLGGDHSISWSVPLFDDGLVQPDVAPHDGIYSGIFTPMEDGLYSISVAASGLSGDGSFQDIRIVNHPGSLMPQDQINFGCKNSTKPRCISAVPRGSFSRVQDMMGTVAVENSATFKPGLPMKIMDFTATTLPDYGIDFEFTSPRLLGSDASPDEFRIYMAPHADNFIGSTDVTKLLIIQVGERPGTRVTSFLNAAAKAVPYYAVEAIYGEQKGGPSNVIGVVPTKEGSLPFPTTTSTQPPTTTAPSTTTEEPTTTTEEVSTTTTEMPTTTTEYPWPSTSTTTGFPTTSTTEESEDPEIPSTTDYPSTSTTSEAPSSSSSTTTEESEVPSTTSDLPSSTSTTTEVPSTSTTEDSEIPSSDLPPSSTTTEVPTSSSTTEDSEIPSTTSDLPSSSSTTTEVPSSSSSTTEESEVPSTTSDLPSSSSTTEAPTSSSTTEDSEIPSSDLPPSSTTTEASTSSSTTEDSEVPSSDLPSSSTTTEVTPSTSSTTEDSEPPSTTSDLPSSSSTTTEVPSSSTTEESEIPSSDLPPSSTTTEVPTSSSTTEDSEIPSTTSGLPSSSSTATEVPSSSSSTTEESEIPSTTSDLPSSSSTTTEASSTSTTEESEIPSSDLPPSSTTETPTSSSTTEDSEVPSTTSDLPSSSSTTTEASSTSTTEESEIPSSDLPSSSTTTEGPSTSSSTTEESEIPSSDLPPSSTTTEETPSTSSTTEDSEIPSTTSDLPSSSSSTTESSSTSSSTTTEEGEITSTTTEDSEITLTSSLSTSTSTTEPPEITSTTEDDEASSTTTERGSSTSTTSSPPITSTTEDDESTSTTEEGSSTSTTSSPPITSTTEDDEASSTTTERGSSTSTTSSPPITSTTEDDESSSTTEGGSTSTTSSPPITSDLTDPITSSTTETTTPEEDETTTDASSTTVEPTSSSTTVDPSEPTSTSTTDPSTTESESSTTTPNPTEITSSTTEFSSTTTEEFTEISSTSTTVEPPISSDLTEISSTSTTQQPSTTEDFSSSTTEVPSSSSTSEATSEIISSSTTDASSTSTTEDSSTTTETDPSSSTTVSDNPTESTTSTTQEPSSSSTTEEDGESSSTSTTSESSTTPEFTTETGSTSSTTSESPSTISDAPSSSSTTEGSSSTSSESSTSTDSSSTSTTSDAPSSSSTTTDESSSSESPSTSPEPPSSLSTSEQASSSSSTGSTDPVDSSSFRVISSHALLVILSCLSIYFNRIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG86</accession>
    <name>A0A1D2NG86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG86"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="19626" checksum="E38D4D54E3FE9AEF" modified="2016-11-30" version="1" fragment="single">QQLKVISLIMANQQFGNGQSQSPMSTNVPDGRHPPPTPVNIKQTTALNLFLMGQGRANVQLGFPTPQGLMDYFGNVNEETMASQQPQQQQMPVEFATAAGNTVPLPANNTGRRPYKSGVKSGSPASDSKVGEAPGMRMTRMNRIHQTGSRHWAMEIQMVARAPQLLTKNCSQIPLNFILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGG1</accession>
    <name>A0A1D2NGG1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000047">
        <property type="protein sequence ID" value="ODN04327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGG1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="436" mass="46635" checksum="9ED9758C571E5EDA" modified="2016-11-30" version="1" fragment="single">MERPKEKKGLGRMKDARFHFKNENTDDFVSVPNKNDPKYQTLPYNAKLFAPFANKHEQDQFEKSMQQMQIIQADHHLNSQLSSHQHNQHHHHQHQPSSQQQQPFQQQNQINNSTTTNYHNNYNSNCSSNTSGTTEENGGNNMHSTDPTNNGTNNKGNTNLINNSSAATISSLQQLHHLLSISSGLHQQNARAGNQQQHSSSYSGGAPNGSSVSNVPPSVSTTMTTSSVPNGLQTVHSTQANNNVSRGKALPILGNGGESNNSTNNGGIPLAFPVIRPSNFYPTGAPPSSSTTNGSSSSATTTTSSNIITANNGGIINSGLSSIPSGPMMPLVASARHNGLLNSQNTTCNSNGNSLEISLTGTNTASLSSTGSNDTGFVSSGSSCSNSGMTISSQSRQQQQQQQQLQQQQLKPALPPKPAKPTPPPRQAHDMFTFNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGL9</accession>
    <name>A0A1D2NGL9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02566</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGL9"/>
    <dbReference type="OMA" id="IVWIAFR"/>
    <dbReference type="OrthoDB" id="8297374at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905529" evidence="3">
        <location>
            <begin position="32"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN04106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="490" mass="54632" checksum="5A873102B6810B51" modified="2016-11-30" version="1">MTKALRMACSSGSWMIWLILLMGILIEKTIGEDETTTTAAPTAPPGKKTGDEQVARAAPEPTESLLKTFQNLYANISSLRDSTDCKLESSEAHNDHRHWGTVETLEFLSGMRPENKMSKAEKWMALNKTRLYLARIGYLKDPGSLVFVQKQIITLKLEGCPDGSIWRKQGGGTEEDTKYQGYGGSLKQHTDQPWSYINKYTCVDYNKPCSHTFYVITNISPDLPADFIVREGGKTAPHEFTCAVPYCNIQDCQQSATKVYNRRSYPPYFIYWDVPVSLKPLLGIESNELMPPLNATPSDLVAHPINKAGVQITWSLQRKKTKDETKLITISGDHKEWNNSFREEVVKKDRIGASFASTFAVSQADPAKHTGIVECVIIDGNGVVSTPNVEPGERLYDYRGDVNVHVLPRWQLWGPVAVSVVCILLVILIICICPRKMEHDDGTRYTKDEMVVPTGGDTGPQPMASEPQPSTSMEKQAEPEVKGDETNLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGM8</accession>
    <name>A0A1D2NGM8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGM8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="21884" checksum="44B1A23525CF0D3C" modified="2016-11-30" version="1">MANQQFGNGQSQSPMSTMVPDGHCPPPTTVNMQQTSAFNLFMMGHGRANVQLGFPAPQGLMDYYGNVNGGMVASQQPQQQQIPVEFATAAGNTPSAYKSGVKPGSSASGSEVGEAPGIRMTRSKSKAVTFAYPPLSDAAPNGKSPLGNGNSDGGKSSTTSDQELFQNCNLLTSSLFDIYLPIFSFNSMFAIISTTSYMKKITSDVIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH50</accession>
    <name>A0A1D2NH50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-related protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000041">
        <property type="protein sequence ID" value="ODN04542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH50"/>
    <dbReference type="STRING" id="48709.A0A1D2NH50"/>
    <dbReference type="OMA" id="WERDNDN"/>
    <dbReference type="OrthoDB" id="18339at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10207">
        <property type="entry name" value="ASKHA_NBD_Arp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="420" mass="46817" checksum="3E7BFE96744398CD" modified="2016-11-30" version="1">MPLYEGIGLINEKHPVVLEIGQAFTKAGFAGENAPRCFIPSTVPSKDNPSKVRKLIDYQDESDLYQMLVDFLNTIYFKHLLVTPKDRKVVIVESLFCKSQWRHTLAKVLYLHYEILTVLWIPSHLAAVCSTGADTALVVDVGYSEALVLPVVNGVTLLNHVQAQDLGSKTFDENLKTLLLDNCTNKPKEELEPLLTPEVIEDIRLRACFVTKIRRAQFLSDPSFSSNLNPQLKPFKYEIDGDNFVEFEGILREQAAEVWFHNKDPEGSSLPYMILDCLASCPIDTRRKLASSILITGGTPMLPGFKARLVRELKKIESELGETKPDFKDEKFTEKFRNGTYEFRIFSCPIKENCVNWLGGAVYGASEAVNLRGVTKEFFMKNEIVPDWCNPGCNSVTGIVGVSNAASSPFGSGVGLPKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHE7</accession>
    <name>A0A1D2NHE7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nicotinamide riboside kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000037">
        <property type="protein sequence ID" value="ODN04694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHE7"/>
    <dbReference type="STRING" id="48709.A0A1D2NHE7"/>
    <dbReference type="OMA" id="XTRATED"/>
    <dbReference type="OrthoDB" id="339325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="29263" checksum="CFEBF7636AB1A79F" modified="2016-11-30" version="1">MNKMSNYSRLVVGISGASCTGKTTLTKLLRASFPWSSVIHQDAYYHPNDPKYHVYLPDVKHFNWDLKSAIDFSKMEKDLQTVLSRSGESKQQNELHIDEQLLHFPNDKFVKKHQPNENEVKYLSSRFSRIPLTILEGHIVFSHPDFFRLCNLKYFLTLNQDELFSRRRRRVYDPPNPPGYLEKYVWPAYVSRLEEIKELPGINYYDAKTVSLLDMYHQIKQSITLEMASMISPTPTIEDSDAQEKLSRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIY1</accession>
    <name>A0A1D2NIY1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor glial cells missing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_01450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000027">
        <property type="protein sequence ID" value="ODN05238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIY1"/>
    <dbReference type="STRING" id="48709.A0A1D2NIY1"/>
    <dbReference type="OrthoDB" id="6241117at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042063">
        <property type="term" value="P:gliogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.670">
        <property type="entry name" value="GCM domain, large subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3530">
        <property type="entry name" value="GCM motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039791">
        <property type="entry name" value="GCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036115">
        <property type="entry name" value="GCM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043020">
        <property type="entry name" value="GCM_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043021">
        <property type="entry name" value="GCM_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003902">
        <property type="entry name" value="Tscrpt_reg_GCM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12414">
        <property type="entry name" value="GLIAL CELLS MISSING RELATED/GLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12414:SF8">
        <property type="entry name" value="TRANSCRIPTION FACTOR GLIAL CELLS MISSING-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03615">
        <property type="entry name" value="GCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90073">
        <property type="entry name" value="GCM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50807">
        <property type="entry name" value="GCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GCM" evidence="7">
        <location>
            <begin position="39"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="317"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN05238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="579" mass="62465" checksum="8C9FCABA1DBD3546" modified="2016-11-30" version="1">MMKAIQAPTSLPATMTVSASSNAPSSHSHHQSRLSSSQTDWDINDATVPSVNQFDSFHEWADGHCRYVYSPDCEQAKRHTSGWAMRNTNNHNVHILKKSCLGVLICSLSCTLPCGTELRLRPAICDKARKKQLGKACPNPRCSGFLQILACKGHCGYPVTHFWRHTQSGIFFQACQNMCPYYAKGVHDHPQPETKKSVEVRKKIITTHTGLPKKVRIPKKAIIQVPPKSGFKVRRKRKILVDKRVSVCQMNPSDAHITKGCYRCNQPSCICPLETTMSKLGTGGSSAPWSLSQGPAVAAALSQAAVAAAANSWAATSSSLTNTPPPLTHHHHHLSTSHHHHHHHLQSSSYQQPLSTGRVLEFPQFPESASSSFSKLPTSGSCSTYPTTTCEGFFKPSDIFHLDYYDQASQSSNSNNTSATTNNANNSAVNHAAYYGIGAGGSCANSGNHAYGDYTGSDSLIADAALQSISAGPPWSIQSMPYANNFMGGGNTSTTGSNTATSISANNGVGISCAIPSTAAGLWSSKVGSSGYFGPIAAEYSADLYTNECFNYYTDNNNYCWTQQQSNSNHNHGPSHLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJ06</accession>
    <name>A0A1D2NJ06_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_01737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily. Sigma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJ06"/>
    <dbReference type="STRING" id="48709.A0A1D2NJ06"/>
    <dbReference type="OMA" id="RIPWDYP"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="90"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="27271" checksum="1314165EA6665805" modified="2016-11-30" version="1">MSDTPKYRLVYFDVRALGEPIRWIFAYSGTPFVDDRIPWDYPTWFSTRKPDFSSTVGQIPILYEEGKRELCQSHVISRYLAKKFGLVADNDWDEAKVDEVISLVHDLFITWRTTLFERDPERKKQMKLIVDQKFKLYYAKLSSILEEEKGDFILGNKVTHADFWLANFISIWDEPMAGDRPIMPEGWPEPCEDDIFIARTKEYPLLNKHKEAVTSLEKIQEWISKRHQTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJA6</accession>
    <name>A0A1D2NJA6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000028">
        <property type="protein sequence ID" value="ODN05195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJA6"/>
    <dbReference type="OrthoDB" id="7692390at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="68" mass="8149" checksum="81B527D928BCD47C" modified="2016-11-30" version="1">MSNRREEERRQREQQTKTVQRRGHKPNRFQWAHLKSCNHLTLAPGRLFEKAPPTPTDSLDEVEMQIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK64</accession>
    <name>A0A1D2NK64_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Charged multivesicular body protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK64"/>
    <dbReference type="STRING" id="48709.A0A1D2NK64"/>
    <dbReference type="OrthoDB" id="3973241at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF12">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="196"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="35"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00041078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN05505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="259" mass="28479" checksum="C695B1334A4B3603" modified="2016-11-30" version="1">MKRLVGLPKKGTGGSAAAYKPQALNDIVKSTDSKVVELDRKIEQCDAELRKINNQMKNGIPGISKRSLQEKARGVLVRKKRFEQQVEQLRDKSFNLDSLAMNITAAEDTTTIATVMQNGTKQLKKQLRKIDLDEIEQTQDDLADLMEMTDDIQAAVSKNYDVPQDIDDDELNSQLELLGDEIVADNDPSYIDAVLEPSNAPLTRKTSSKNRRGGGGGPAGPTAIEVDDYGLPILPIAPSEEKIPSTSEEKDIDTNTNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKX3</accession>
    <name>A0A1D2NKX3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polycomb complex protein BMI-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00746</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKX3"/>
    <dbReference type="STRING" id="48709.A0A1D2NKX3"/>
    <dbReference type="OMA" id="IECQHTF"/>
    <dbReference type="OrthoDB" id="1305878at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035102">
        <property type="term" value="C:PRC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990841">
        <property type="term" value="F:promoter-specific chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000033">
        <property type="entry name" value="Polycomb group RING finger protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10825:SF29">
        <property type="entry name" value="POLYCOMB GROUP RING FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10825">
        <property type="entry name" value="RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="81"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="247" mass="27571" checksum="2A529C0FE2F04A3B" modified="2016-11-30" version="1">MELAIRLANDVFKKLVTLQIVLQNFSPAPLKSTMAADDYHPISKHGKTTAASAVSPSSIKKPKERVPAKPDMPEINCYLMCQLCSGYLIDATAIIECQHTFCKSCILKYLETNSYCPICDVQLNKAKPHLSLRSDVIIQRLVYKLVPGLLVSEIRRRRDFSIKNGMDPVEAAELASNSIAAEIEASSDLSTVLSLDDVVSLSVEYFRSRLKAPSSHIYYAKQFSIFRLLHFSTACQQCGRKLLAIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM14</accession>
    <name>A0A1D2NM14_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ubiquitin-conjugating enzyme E2 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN05976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM14"/>
    <dbReference type="STRING" id="48709.A0A1D2NM14"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="626"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="878" mass="99550" checksum="B9A32A5570C5C926" modified="2016-11-30" version="1">MTSKRSDSATRKRSYLSMASGVNEKEDVELDHESAIGSMEPGSNNADGNGNVNEECDIKNVAISQPLLKGDKVLAVGNIGGWQWRRKRKDSKMVTGTVVLGKEQTLSILWEHGKIEKLNSKSDLLSYGDRVFVLDREFITTGSRVVVTGHPDRLVGTVLNKRYIAAASCTVNSDVIFDNVDTKTLSRHPFGGSYNGSKILFDSWIGIIVGSRSRLYLKAIEDGAEFSVIQDGRYPQSFVVGEEIKLGLGMIWNAQNFSTGDSLWLANAIKYYNTSAIVTNVVIEELEVVWIGKATSPKADYYPYEFPDAPDKIIPYESLGDVGYLSGENCYHIFRKNVWKYSSSSNDIPVSRDKWMGKWLKIVDWDRWEYADCEIIADKEKYLNKELALQIECVRSIIDVLWDNGNRSTVGTCDVIPAHVGSAWSEITQLHSGAIVRDRLDFENKDKYGVLLDVDKEMNATVKWITPSGKEGGFTEMLSSNVPLYNLVEKEEYEFISRISQCPLVHSKGRFQIGVVIGIKSSTGEVEVRLPDGKLEYRMPHQLTHYKCDVLYCPRAKEWVSWYEHILPPSGIISVTPSSESDAQELSSWDECLSVPIMKRLDFTDNVPTDNIFACEDTVPRVRETQFRRAVEKEVAEMGEDGQCGLPEGIWVEYYLNRGDIMSAVVAGPVDTVFEDFLFIFDIFLLEDFPRSEPHINFRSMGVTLFPRHFCKSGAVFLPDTTRLTDEDFTLSYIQNLLLEIKDFMARPLDQIRKLDNKELGPIKHENVEELHKFLSLSVLDYTIAILRTPPQHWNSLIGHHFSEALPRIIERYTKAPMQLKRPTASVNNEKGDVPEPVEFQLVTVHGVIPTVKVFRQGWIHYRIFMHLGRAAERLQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM48</accession>
    <name>A0A1D2NM48_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metallophosphoesterase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM48"/>
    <dbReference type="STRING" id="48709.A0A1D2NM48"/>
    <dbReference type="OMA" id="MDVGDIH"/>
    <dbReference type="OrthoDB" id="5977743at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF4">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="48"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN06165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="399" mass="46203" checksum="414BAD3FB16C66C6" modified="2016-11-30" version="1">MRFLKRRTRLALIALGGILFTVLCIEHLSYLHNTTYWPEIDKSKEDVLRILFVADPQIQGEEMEHFLYGWVTRWDADKYLQKNYRLAKNHVLPHVVVFLGDLFDEGSIASDPAYRRYFSRFRKIFSLPKRQDSSPSSIKYVFVPGDNDVGGERSEPVNDIKVNWFAKLFGDFKSVDNVDRSGIDVQFIKMNLFMPEQYKNPLKGFENVINGTKKPDIRIIVSHVSLLSYMTNSVEKVVEGFRPNLIISAHSHSSAYMRYTPGTSNQSPRIIHDFLLPSRKGTNKLDHDHEDLYTKSPFTLDLKSVSSELHEILVPTCSYRMGVSNMGYGAMELYRDGTMKYTVLWLPSRFKQLFLYAAVYILMKIILTPFLCWKLGTFVCRKIKEMRVLDSAKQYIAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M179</accession>
    <name>A0A1D2M179_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007466">
        <property type="protein sequence ID" value="ODM86726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M179"/>
    <dbReference type="STRING" id="48709.A0A1D2M179"/>
    <dbReference type="OMA" id="CMINELP"/>
    <dbReference type="OrthoDB" id="6509516at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF1">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="281" mass="31996" checksum="C6324295A7EAAC92" modified="2016-11-30" version="1" fragment="single">MNDLSVNGFRWKLECGMSVVSKVYFTNCTADSPARCLLQGNKQFNLKYGCNWCENPGERVEKGKSHCRVYCTDFEHVLRSGEEYRIKASESVFENGIKAASPFLKLNTFNIVDGFTVDIMHCVYLGIVRTLTNLWLEASHSDYYIGKAVSEIDNVLLNCKTPSEICRNFRSIKTNKYWKATEWRSWLFVAPIVLKGILPKQFVKHFQKLASLIYDVTCSAISDSSLVEAESMVLKFSGSLERLYGKSNLTFNVHQLNHLVQSVKNWGPAWGTSAFPFESFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1I3</accession>
    <name>A0A1D2M1I3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007078">
        <property type="protein sequence ID" value="ODM86825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1I3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM86825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="152" mass="17108" checksum="BC3BA0C56365E867" modified="2016-11-30" version="1">MLDTSSISSPGSPPCNRIHIVTSTIKTPPESSRFNCRLTIDKKFKESIKQSGDQGMITSLTPPLAKVPESHHLQTHLRVLLCMRKTPFHPLLGISFTFICRKSQEPIALAVAYAQLWRLSCNAANYHYSHTKYVSSDELHVTYENGNDDTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1M3</accession>
    <name>A0A1D2M1M3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibroblast growth factor receptor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007014">
        <property type="protein sequence ID" value="ODM86842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1M3"/>
    <dbReference type="STRING" id="48709.A0A1D2M1M3"/>
    <dbReference type="OrthoDB" id="5984265at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF611">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="6995" checksum="120B8F9699D29445" modified="2016-11-30" version="1" fragment="single">MDFLESRRVVHGDLAARNVLLTAHKVAKITDFGLSRQLYNYSVYVKTQNVILKRDKPNYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2X4</accession>
    <name>A0A1D2M2X4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">U1 small nuclear ribonucleoprotein 70 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005569">
        <property type="protein sequence ID" value="ODM87319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2X4"/>
    <dbReference type="STRING" id="48709.A0A1D2M2X4"/>
    <dbReference type="OrthoDB" id="4207594at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="U1 small nuclear ribonucleoprotein of 70kDa N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="84" mass="9280" checksum="5096429073C50FA7" modified="2016-11-30" version="1">MLGGVLGHSFLPPNLLALFAARDPIPYIPPVAKLSHEKPVRYCTGVANISTFLRIPPTHLQNRRWKQGMSGWKESAKRKGTGCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M5E1</accession>
    <name>A0A1D2M5E1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NUAK family SNF1-like kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_18494</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003987">
        <property type="protein sequence ID" value="ODM88188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M5E1"/>
    <dbReference type="STRING" id="48709.A0A1D2M5E1"/>
    <dbReference type="OMA" id="VFCRSEY"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050321">
        <property type="term" value="F:tau-protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF93">
        <property type="entry name" value="NUAK FAMILY SNF1-LIKE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="37"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM88188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="30158" checksum="2FDD877BCAF20AF8" modified="2016-11-30" version="1">MVLREHNDPLNQSRGIMGPLENATGVQNNRGRLRQRFDFIRKLGQGTYGKVQLGIDKETGQEVAIKTIKKSKIETEADLIRIRREIQIMSSVRHPNIIHIYEVFENREKMVLVMEYAAGGELYDYLNERKILEEDEARRIFRQIASAVYYCHKHKICHRDLKLENILLDEKFNAKIADFGLSNVFSDATLLKTFCGSPLYASPEIVRGTPYKGPEVDCWSLGVLLYTLVYGAMPFDGSNFKRLVKQISNGDYSSQRNPLKPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M613</accession>
    <name>A0A1D2M613_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative leucine aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_18276</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003633">
        <property type="protein sequence ID" value="ODM88406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M613"/>
    <dbReference type="STRING" id="48709.A0A1D2M613"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903505" evidence="9">
        <location>
            <begin position="20"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="175"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM88406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="433" mass="48150" checksum="7202D4BB17354B52" modified="2016-11-30" version="1">MACNLFLLINLIIITVSSTEEPAPVEPGQRLIKLSVNEPAKWMSEQELGQLLKEHGPLGFLDLTLKGDDSAPTQNKALYTYPSGPLQSTVVRKLFPYLKKDRMESFVRKMSSFPSRFSRHFTGPGYADDWLIQEIASVLGNRQTKEGHSPMRRVYSPDLHAGVGIPRRKYTAPTIIVTLDGEDPLKKELIILGAHYDSINGPYHPILDDEGAAVTETKVAPGADDNATGCAVLLEVLRLLVQFGIKLKYTLEFHWYAAEEMGNLGSGQIAYDYFREKKLEVYAMLNLDVIGYRSDKHAKTIAYSNDGTNQELTTFLKMLSKEYVEYGMTERPCKAGCFSDHDAWNQSGYPAAFFTEAELTPFIHTEKDTIETVNFEQVNEFAKLAVAFVIELGELSEIPSIPDPEASLASSLSKSAWLWTAMWLLGGASAAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M684</accession>
    <name>A0A1D2M684_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High mobility group protein DSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMGB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003536">
        <property type="protein sequence ID" value="ODM88485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M684"/>
    <dbReference type="STRING" id="48709.A0A1D2M684"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21978">
        <property type="entry name" value="HMG-box_HMGB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF32">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="102"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="102"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="179" mass="20552" checksum="26954EBFC00CF1F1" modified="2016-11-30" version="1">METVPEKALKRPRGPMASYAYFVKHCREQYKGQSCRFADLTKECSEKWKGLSEEERKVFKDMAAQDNKRYKVEKKKFLEQGGVGYRSKRGTCRKRSALPTTPVKPLSGYSWFSRDEGVKLKGDPNVVGTRGLVGKTLARMWAVADPATKQKYQALAERDKVRYAKEMEMEAQKKQSPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M689</accession>
    <name>A0A1D2M689_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003521">
        <property type="protein sequence ID" value="ODM88500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M689"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="29466" checksum="831C2FC115A311C5" modified="2016-11-30" version="1" fragment="single">MIQTAYDIFYYLYEELDPMIHDPPGMQRKAMEFLENCLAAEPVLNFTTYGCPREIKQLVVDEYVMKKLETYYEGQPEELNNVLKSLEHVEIRKDRRYVVELYDIYVEINWKVADFVHSFCFEHFGNEFNAHHYFESELETLFLFPEVQRRWFSKAKDLRYARGILGTSNLKIRMQQLDKVAAVGHSLSRYNGTYWLHRPNVDPMLMYAEDSKISSGGSDGTREESRLAFAKHLYENPHFPKSNIFALKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6C1</accession>
    <name>A0A1D2M6C1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mesocentin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003491">
        <property type="protein sequence ID" value="ODM88513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6C1"/>
    <dbReference type="OrthoDB" id="10045365at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="555" mass="58317" checksum="AA887B0C15C8608B" modified="2016-11-30" version="1">MVNQSMVLHLEKMDYSNLVMTSYGVLIANGQPLQPTSFSPMVCLFMKHHWDLMVSHSSQPRYGANGEPIYGAPLGEDGQPLQPIGYDADGQPLYAVPIGPDGKPLQPTSFSPDGLPIFEAPLGVDGQPLKPTSYGANGEPIYGAPLGKDGQPLQPIGYDQDENLFMEYRLVPMVNLEPISYGDDGLPIYEAPLGSDGQPLKPTSYGANGEPIYGSEGKSHEPVGYSPDEGAVYGVPIGPDGKPLIPVGFAADGVPVYGVPSGSDGQPLKPTSHGANGPDGQPLQPTSFSSDGLPIYEAPLGFDGQPLKPTSYGANGEPIYGAPTVPNGISMQATSAGGGPPMYEDQFAEDSGPTGRSLMNGSEDSGPTGRSLMDGAEDSGPTGRSFFNEAEDSGPAGRSLAGYGGAVGQDGQPISGSSQKALGKMVHVLVSMEDLWMLQGVLARELMLLEAEVQALLMEQEKLVKHAELHNKTYSGKALNFLPLKPTSPVPLELLLEQQIAECRVKHQDKLQGLLGPNAGFGGLGSLFGGPADGQRGGGQASYQVKWNMMKLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6R1</accession>
    <name>A0A1D2M6R1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Gamma-aminobutyric acid type B receptor subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_18009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003330">
        <property type="protein sequence ID" value="ODM88670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6R1"/>
    <dbReference type="STRING" id="48709.A0A1D2M6R1"/>
    <dbReference type="OrthoDB" id="2150267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="360"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="552"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="615"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="720"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="638"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="720"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM88670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="764" mass="84915" checksum="18995F851418438A" modified="2016-11-30" version="1">MFTRSRTSARHVPGSSWRGSRWRSVNVLENVEGSLHIHERQAEQEVIKDMQLFIVVGILLAIDFAIMTTCTSLTPWSGTPRNRGLREWETQLAIFFGQTNPNNDDIMIIGRTSTASRRLAHGDLADNLIYIILKFKIVLLSNTHRLFGCFFGVGDAQRVDTGLKDSKYIGMRVYNSVLGAPLSHVLTDKHDASFLIISVFHHLLHHCHALSRVPTQGLKRNPKGTVEKRLRPTIKPPSTTRRASGLRCTKPSSNCEAQHAYPDQKILNFFGSIPIPKALAKILGDDAQDILHDAMHNLALPKSEVLKKEGEPVLAPFKPTCREKVPGLATALAAAQPDNNGTWEPATSVVAKTILINSHGSGLPDKVKSENEQTLSNSPSEEPVTIEEKSLPKIPEEPPTSCAARQQQSLSVVIMQPIQLLPKYLRLNKSDLDLSEDPENARWDRELDAKPGGSKHHQSTSENTLVVKEEGKPVVSTTTQQEIWTMLQKDRRYMDRNIYVEEEEEIEHQICDAPVTPLLLPQSGRNLNDSSRPPLPKPISLLLPGSSSAVKLQLPKQSKTDEQQDNELINGKPTTGKTPGGGIVLVAPPPTKHAAAEAEPELGANVKHPHYNTLASHHQQSQQHAYYNVGSRSTHDPSTYSQTLTTTSSSRPIPTAYQHASTEEIHVRGHVSSQPIMSKNRSYCVPKRLDNSNLNLSEINLDVSLLPIFHNILSERSRSLRERSRSTEQNKRGASTLRSKRNKPNNLLLSCPNIMIKCDIVEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7F9</accession>
    <name>A0A1D2M7F9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein eva-1 C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003074">
        <property type="protein sequence ID" value="ODM88903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7F9"/>
    <dbReference type="STRING" id="48709.A0A1D2M7F9"/>
    <dbReference type="OMA" id="WCLLIVE"/>
    <dbReference type="OrthoDB" id="5970528at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22828">
        <property type="entry name" value="Gal_Rha_Lectin_EVA1_EVA1C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22829">
        <property type="entry name" value="Gal_Rha_Lectin_EVA1_EVA1C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.740">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000922">
        <property type="entry name" value="Lectin_gal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043159">
        <property type="entry name" value="Lectin_gal-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46780">
        <property type="entry name" value="PROTEIN EVA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02140">
        <property type="entry name" value="SUEL_Lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50228">
        <property type="entry name" value="SUEL_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903573" evidence="1">
        <location>
            <begin position="21"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="SUEL-type lectin" evidence="2">
        <location>
            <begin position="30"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="SUEL-type lectin" evidence="2">
        <location>
            <begin position="126"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM88903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="220" mass="24276" checksum="6BDF7F060D7229D4" modified="2016-11-30" version="1">MFSSFADMLFFRYFFTALLSGTLRTYQKAACDEEWVSIRCPAGTTISIQLAQYGKTAPAASLCRSSNPNIFPDLMDPTVVGLCQKKPSCKFQTSPQTFGGDPCPGSRKFVEVAYKCRPSEFRSVIGCQDDVIQLSCNKSSRLAIYSANYGRTEYESVSCPQPAGVQEETCLASYATETVMQMCHGKRRCALGVDSTFGNPCKPESRMYLKVIHTCGKKCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M9G6</accession>
    <name>A0A1D2M9G6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Neuroendocrine convertase 2</fullName>
            <ecNumber evidence="8">3.4.21.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Prohormone convertase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_17110</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Release of protein hormones and neuropeptides from their precursors, generally by hydrolysis of -Lys-Arg-|- bonds.</text>
            <dbReference type="EC" id="3.4.21.94"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family. Furin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.94" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01002531">
        <property type="protein sequence ID" value="ODM89572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M9G6"/>
    <dbReference type="STRING" id="48709.A0A1D2M9G6"/>
    <dbReference type="OMA" id="HERFIAR"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016486">
        <property type="term" value="P:peptide hormone processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000020">
        <property type="entry name" value="neuroendocrine convertase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884:SF13">
        <property type="entry name" value="NEUROENDOCRINE CONVERTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="P/Homo B" evidence="12">
        <location>
            <begin position="240"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM89572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="403" mass="44222" checksum="E2F37B87911BD60B" modified="2016-11-30" version="1">MLRIRMLDQPYMTDLIEANSMGHEPNLIDIYSASWGPTDDGKTVDGPRNATMRAIVRGVNEGRNGLGNIYVWASGDGGEDDDCNCDGYAASMWTVSINSAINDGQNAHYDESCSSTLASTFSNGAKDPNTGVVSGTSSFHNNSYAISSSSLEGNESHSGTSAAAPEAAGVFALALEANPSLTWRDIQHLSVLTSKRNSLFDAKGRFHWTMNGVGLEFNHLFGYGVLDAGAMVALSKEWKTVPARYHCDGGSIKEQRRIPSRGTLVLKLDTKACQGTDTEVNYLEHVQAVVTLNSTRRGDTNIYLTSPMGTRSMILSRRPNDDDRHDGFVKWPFMTTHTWGEYPKGTWTLEVRFVGDKPQAGWLKEWTLMLHGTRDAPYVNLPVTDPHSKLAVVKKAHEDRKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MA81</accession>
    <name>A0A1D2MA81_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_16786</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:12706"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01002305">
        <property type="protein sequence ID" value="ODM89896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MA81"/>
    <dbReference type="STRING" id="48709.A0A1D2MA81"/>
    <dbReference type="OMA" id="FWPCNSS"/>
    <dbReference type="OrthoDB" id="73890at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000027">
        <property type="entry name" value="Protein-L-isoaspartate O-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM89896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="230" mass="24793" checksum="E4F6BCFA6936BD4E" modified="2016-11-30" version="1">MANRSHGVDNENLISNLKTNGKFKSSRVEAALRATDRGDFSRIYPYKDSPQSIGFGVNISAPHMHAHMLELLADNLTRGTKALDIGSGSGYLTVCMALMVGETGKVVGIDHIPELVDMSIRNVKKKHATLLETGRVKLVGLGDGRKGYEADGPYDAIHVGAATPQIPPALVSQLKPGGRMILPVGPPSGNQELMQVDKLSNGEIRKTSLFGVVFASLTDPDTQWPRRTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAT8</accession>
    <name>A0A1D2MAT8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CDGSH iron-sulfur domain-containing protein 2 homologue</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_16576</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the CISD protein family. CISD2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002169">
        <property type="protein sequence ID" value="ODM90106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAT8"/>
    <dbReference type="STRING" id="48709.A0A1D2MAT8"/>
    <dbReference type="OrthoDB" id="449252at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045131">
        <property type="entry name" value="CISD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680:SF5">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="7">
        <location>
            <begin position="136"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="17927" checksum="369FCE632337528D" modified="2016-11-30" version="1" fragment="single">SVIKGVVLVDSDIGKLLGTLLNGSRAIYGSFGPLPVDLCCLGGALKAFQLAPLGRCGFVTLVFFEDSVIKGVVLVDSDIGKLLGTLLNGSRAIYGSFGPLPVDLWALRGPKGGDSSTGGSSRRGKVNLNIKKDNTKVVDTCDIEEIGRKEVFCRCWRSKSFPYCDGSHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBY0</accession>
    <name>A0A1D2MBY0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative GPI-anchor transamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001991">
        <property type="protein sequence ID" value="ODM90394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBY0"/>
    <dbReference type="STRING" id="48709.A0A1D2MBY0"/>
    <dbReference type="OMA" id="IHYRIMW"/>
    <dbReference type="OrthoDB" id="192611at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003923">
        <property type="term" value="F:GPI-anchor transamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028361">
        <property type="entry name" value="GPI_transamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067:SF1">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="148" mass="16970" checksum="8820B0366AA6C413" modified="2016-11-30" version="1">MTGHGGDGFLKFQDSEEITNVEYNEIFFMVDTCQAASMYEKFYSPNILAVRVVLLGRIHYRIMWTQASECTSLTDIPTTPSSSWKLFGPTVAKTMGQFLKVCPKWACISTVGVRRDLFRRDPDKVRITDFFGSVRKIQIQRKSLISRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCM3</accession>
    <name>A0A1D2MCM3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001872">
        <property type="protein sequence ID" value="ODM90634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCM3"/>
    <dbReference type="OrthoDB" id="10660008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="225" mass="25202" checksum="70A41CF3A8A9C196" modified="2016-11-30" version="1">MLPYQVATSGVPYGYTLVPQQVLGPGQRLVPVPGGRNVYSLVDMDDEGRLRSPTSPSSFPSRLSSTRPARATNFWRTYDYDTRSLTPRYLAPPPDRSTIRPITPTLDEEPDQFLQSLRPSGRRGGSRLVTASYSGGAERVYTPTSLTAHRVQSLYKELDEPLYAPELKNFDYTACLRRDRAADQEKVRGVYFGALFCRSLHPDFLTRGKSDHPSSLRDLAMTPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCW5</accession>
    <name>A0A1D2MCW5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15845</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001773">
        <property type="protein sequence ID" value="ODM90838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCW5"/>
    <dbReference type="STRING" id="48709.A0A1D2MCW5"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="621"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="652"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="684"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="713"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM90838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="741" mass="85317" checksum="9960756F4408BC43" modified="2016-11-30" version="1">MESCSNCIFCTSPCQSKFTIFDGKPVKLKKDECENDNLSANCEFGDDSNIETNLKVILITRKILNIERRSCSKFLRSLQGQLHPEFWLEVCSSCDQLVSEFWAKSMEIGRLERRLKEIKRELTEFIQKSGDVRGEIAAGIGPVWNKIRERILTGVEPKDETIVPFDEDKVHADDDNDDDFDPTPFLLQEAEDSDFEVPKEEEVDDRSLDEDDADRDSDDYKPIPFSLEEADGSDFEVPNEEEDGSSSDEDLKSEDISKSANPGESSPTQPESSSPPPEKPRKRSPYLKCAECGDLSVSIMRFKHHSQLHKLNKGTVCPECGWLCGNLSTHTSYWHPTTGLKLTMEERLAKREVRVMQVISDESPEDQDAFEIIRSSTKKKLFRCKLCPATNRRETRIRSHLAGHKNPASIPCKQCGWIVEPNKMGFHIAKTHHLNRPSDLSKKRRRKSAPIIFRHSCSECKAHYRNPGDIRKHKQLHESGKGEVCDECGFLVSKLRSHKLRMHKPGSKKKKVDEKEVSVVVSEEIPYYCDHDHMIFPYLSRFLVHRKCYHANEPLLECNECESKLESKQLLRIHLSREHGQKEEIPMEELQPQLCQYCKEEFGSKMKKDLHVAQEHQDKLLSCETCNVRFTKFADYQTHMDTTRAHANKKLFSCEVCGKTFNSNGILRDHRVQEHYEVLGLEPHRCSYCGQILANKSVLDRHIRSQHTKQWKLTCEYCGKGFNAQGRLQAHIKVKHKEVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDC0</accession>
    <name>A0A1D2MDC0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001706">
        <property type="protein sequence ID" value="ODM91007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDC0"/>
    <dbReference type="STRING" id="48709.A0A1D2MDC0"/>
    <dbReference type="OMA" id="EGPARIW"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="53"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="493" mass="55852" checksum="40164CAC7756D1F4" modified="2016-11-30" version="1">MRKTTPVHKVCCNLFTLSILVWIFNLLICSEAQKTAGVKQDSPSKAKVTTSSEWIEGSLNAHNYFRSLHDTPPLVLNDTLSEISQYYANYLLKLAIQNQGSGRVYFDHNPEAGRARIGENLYYSTMPSIGIPLPPSYAVLLWYEEIKDYNFTSAKRKQTSDQQAKIGHLTQLLWSSTLQMGTAYASATLKNNQTIAFVVANYYKQGNLILRDDESKLYLENVLSPTVSDADINAAIVKTDVKSWLKALQKSTANTNETPEKWRKTALMKHNKYRSRFGVEHLRLNSDLCKVSQMWADYLLEKGLQTFNAYGVLNQIESNFIGTQFLRLGESSLFYVTGTNEVSPEGPARIWYSGRRFYQSSQQSKKSVDLQADRFIQLIWKSTTEFCVSYASGVAVNGQNLIYVVANYYPGVNGNKADRMHNIHWNDDNTKFSELIIEEDIDDDDDGCCSFGTILLIILGIAAVLILMVVGSIFLLSVFKKSWYESIVRTFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDM1</accession>
    <name>A0A1D2MDM1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dysbindin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001669">
        <property type="protein sequence ID" value="ODM91107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDM1"/>
    <dbReference type="STRING" id="48709.A0A1D2MDM1"/>
    <dbReference type="OMA" id="HRVFEYE"/>
    <dbReference type="OrthoDB" id="2445127at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012791580" evidence="2">
        <location>
            <begin position="16"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="191" mass="21780" checksum="ABB2CE9CE4A3928A" modified="2016-11-30" version="1">MFSFLLFVTSVNVQCAFEETEGALLMLEDMVETQELREKQLDHRFQLALYQEKRASELQDLKERLTEEHLRKIAEYDKQRESHLKERQAVFQEAFEEDLQRFKSQGALPRSKTSGTDKSTPSLEEIVLDEDSVDLESFLADQNQEDGGDIHKKTEVKDAKEVGDDNASTNSETTGKSNSIKVLSTNDDDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDZ9</accession>
    <name>A0A1D2MDZ9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001624">
        <property type="protein sequence ID" value="ODM91220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDZ9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="336" mass="36271" checksum="CAF4E81730431119" modified="2016-11-30" version="1" fragment="single">AGTGPSLLPVWQNLWLDPYSRTPGTNREYPLGQLLISLVSEIEKEARKYGKDWRLEEPGRQCLIDISTDLCNFLTEAGNAVIAHVPTVTFMYGDQPVQLKSTGQLLLNYAIAIADKAQTLCTPQHPVHYNFRIKTRQILFSAADVFETAARALLNPRNPFDLPALDLEQENAEVAEVATPSPPVPTSVDIANERVVIPSDQAGNKSGNEGDENIGGDANAPNPPSQNLSFAENIQGGKGKRKNSTAGKVDPPSISSSTDSNNENVTGKRAKHPNQFVQNGGTTTLKANAPRPPPPKSAKHGAGTATPGKTVRLQERVSQTSTTDRRRSLRNRGGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME67</accession>
    <name>A0A1D2ME67_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Frizzled-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15454</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001623">
        <property type="protein sequence ID" value="ODM91233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME67"/>
    <dbReference type="STRING" id="48709.A0A1D2ME67"/>
    <dbReference type="OMA" id="MPIVYLA"/>
    <dbReference type="OrthoDB" id="10053709at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042813">
        <property type="term" value="F:Wnt receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017147">
        <property type="term" value="F:Wnt-protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035567">
        <property type="term" value="P:non-canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015526">
        <property type="entry name" value="Frizzled/SFRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000539">
        <property type="entry name" value="Frizzled/Smoothened_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020067">
        <property type="entry name" value="Frizzled_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309">
        <property type="entry name" value="FRIZZLED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309:SF126">
        <property type="entry name" value="FRIZZLED-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01534">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01392">
        <property type="entry name" value="Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00489">
        <property type="entry name" value="FRIZZLED"/>
    </dbReference>
    <dbReference type="SMART" id="SM00063">
        <property type="entry name" value="FRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01330">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63501">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50038">
        <property type="entry name" value="FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903888" evidence="6">
        <location>
            <begin position="19"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="7">
        <location>
            <begin position="32"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="37"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="45"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="565" mass="63893" checksum="8A55F661CBD6489E" modified="2016-11-30" version="1">MDLLLWCISGCLGNHGVAVTPNQSPVDNSLLQSSARCQEITIPMCKSIRYNFTEMPNPFNHETQDEAGLEVHQYWPLVEIKCSDDLKFFICSLYVPICMEDYVGTVPACRSVCERARQVRLSWPDRMGCEQFPKYGKHSICMDEKNGELPGTNAIIPKLDRAGVFTSGILKKKCDSNACACRNPLVTLNPNSYVHQQTGFFQNTSSTISTGSCALRFPAGATVREPEEIRFANYWLTFWSAVTCGLSTITILTFMIDTTRFNYPERPIICISFCYVFVSLGYLTRIYVGHAETACGGGPVPPRSDPAVPKLQPGLHGGVPAHLLLHDKLFHLVRDPHDHVVPRLRPQVEHGGHLREIRSLPTPRRRCRRAIITYDYTCFPGDSISGICFVGNQEYWNLVFYVLVPMGGMLLLGTFFLVSGFIALMRIRSVIVREVRNVHKLEKLMIRIGVFSVLYTVNVVAVLSAYVYEAYVREEWVNKLNCNDCNDVVVENGNFKPAYSVLMIKWVLHVVGDRHNVEHLGVFNENDRDLEEIRVLKVPLHVFPQRLLQLLVLGHLSTHLHPHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEC2</accession>
    <name>A0A1D2MEC2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G-protein coupled receptor Mth</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_15317</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001581">
        <property type="protein sequence ID" value="ODM91368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEC2"/>
    <dbReference type="STRING" id="48709.A0A1D2MEC2"/>
    <dbReference type="OrthoDB" id="6134459at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15039">
        <property type="entry name" value="7tmB3_Methuselah-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051384">
        <property type="entry name" value="Mth_GPCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47154">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47154:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903890" evidence="6">
        <location>
            <begin position="21"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="528"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="287"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="595" mass="67585" checksum="9D4D205D4199D684" modified="2016-11-30" version="1">MKLLILLVIATGFLQPVALAERDVQLTIRKCGNSNLQNVDVVRLPTSFINTTGQLEFSMETHSLLPGNDIESCRPQIMELPSITILRNSSKKSWRQTKLLLENGYLSVANLSDESVDYYGIDEYCIADVHGSGENRIADIKICIQSSSTKRPVLNKCCPLGTILGIRGCVKENDHWEPTFMDFKTLPQSSAQNMNPVYHCPLLSCPPAEREQWLEDGCDTKFYPVNTGKTAFIGRYRTWEILEHPPGSTYCYDRHKNEKGIMRNILVMCNGNVTNLENGNKNPKQVTYLYMICMYIGAVFHLLTTLVYLITWRKQNVYGKTLCSCTLALFFMQTFLGTAHLLGIFGGGETRGSTFCFLNGVFAQYFFIASFTWLLLLNINLWWSFRSIEGNNVWERNRFLLYTIAGWGFPLIVTGISVILDLTNKCRASGVPTPEYGTHTCFIAAWALGYYIYYIIAVLMTITFIFAVITLGTMVNYQKATSNLGANKRAENMRTFILFLKLSVVMGLSWIFELISWVVSKEDSGGHWIWTIFDVYNMLSAILIFILFVCQRKTLSLLQEVHPAFNVLTAEKIDFSPTFRRKDYSSTDATTRVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEP7</accession>
    <name>A0A1D2MEP7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein disulfide-isomerase A5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_15329</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001583">
        <property type="protein sequence ID" value="ODM91354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEP7"/>
    <dbReference type="STRING" id="48709.A0A1D2MEP7"/>
    <dbReference type="OMA" id="FCKKMKP"/>
    <dbReference type="OrthoDB" id="74910at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02997">
        <property type="entry name" value="PDI_a_PDIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046374">
        <property type="entry name" value="PDI_a_PDIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF2">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903900" evidence="2">
        <location>
            <begin position="23"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="129"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="261"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="397"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="525"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="642" mass="72116" checksum="D161E09250DFE1DF" modified="2016-11-30" version="1">MNNIILWTVILLCSLLCVGGNGKGKVTLESLTDVKDHKKLIKIKTNVLVCFGNGRASFTKDNILNLLTEAANEVKGLGTIAVADCSGDVKKKLCKKVKVLPDEGQYIIKHYNNGEYNKDYDRAIKISSLVNFMRDPTGDLPWDEDETAKDVVHLVDNVALQKLLKKENTSGKGILVMFYAPWCGYCKRMKPDYSSAATELISTDAGILAAIDVNKAENNVVRQKYNITGFPTLLYFRNGQLKQHYEGENNKDALVNFMMLLMKNPDAPPVEKPKEPEWSDEPSEVVHLTGDTFDTTLQENPSVLVMFYAPWCGHCKRMKPTYVTAAAKLKEEKITGILAAVDATKDNALAKRFDVQGYPTVKYFKDGELAFDAGNIRDEEAIINFMKDPKEPPPPPPPEKSWAEEESAVAHLTEESFKPTLRKKKRALVMFYAPWCGHCKAAKPEFTAAAEELKDDPKILLGAVDCTIHRTVCEAYDVKGYPTFKLFHYYNKADVESFDGARTKTGFLEEMRPNMAANGDDWVGLQGGGNVHILTDSNIGNFIKSQEATLIMYYAPWCGHCKSAKPEYAKAAEMLTKEAPGSVLAAVDCMRYPSVYEEYEIVGYPTFKYYRSGRLIGEYHHRRRAADFVHFMMRKPKSRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MET6</accession>
    <name>A0A1D2MET6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001521">
        <property type="protein sequence ID" value="ODM91526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MET6"/>
    <dbReference type="OMA" id="SPYDINK"/>
    <dbReference type="OrthoDB" id="10539720at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="239" mass="27481" checksum="E516092C33CB7942" modified="2016-11-30" version="1">MMQRFLERRDMEDLDIALERLGMLNSVTNARREFINEMRLRGVRSQTSFPWRKDSSSEDSQDDWYSLPIKENLGVEKVMVYGGSKLLSRRCRSKLCRSFPYDINRKKPNPNTLISPMMSRMVDPSSTPTLPLVLQQQHSLPIYDALNKNRKTDKFPVPLLSRSKSLEDLRESPNKSKANRFQLLHCDDSSDGSCNGSNSIESPLSLSPRNSFFNVLKGEVSIKQEIDSMSMRIEKLDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MF92</accession>
    <name>A0A1D2MF92_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_15031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001464">
        <property type="protein sequence ID" value="ODM91648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MF92"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="82" mass="9378" checksum="89BEC03B691F4F99" modified="2016-11-30" version="1">MYRQHADQAVLLKFDCTDLPHPPDGVIRPLLETIYFVPVLNTKNGKAKTFSWLYLKLSLEIPEKGFTSCTLIQLANHHQQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFL1</accession>
    <name>A0A1D2MFL1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_14929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01001430">
        <property type="protein sequence ID" value="ODM91753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFL1"/>
    <dbReference type="STRING" id="48709.A0A1D2MFL1"/>
    <dbReference type="OMA" id="SERTVHK"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM AAA-lid" evidence="5">
        <location>
            <begin position="30"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="MCM5 C-terminal" evidence="6">
        <location>
            <begin position="146"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM91753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="206" mass="23790" checksum="710FFE7E3018E9DE" modified="2016-11-30" version="1">MMAKHVMRVHMNAQRVNDQPEQEGELSLLFLKKYIAYCKAACGPRLTQDACDKLKNKYVLMRSGNKEAEESAAHRNPIPITVRQLEAVIRMAESLAKMQLKPFATDVHIDEALRLFQVSTLDAASSGNLAGVEGYTTQEDHELLNRIESQMKRRMAIGTQVSMHTVVQDFQRQKYDEKAIQKVIYTMIRRGELQHRLQRKMLYRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFP8</accession>
    <name>A0A1D2MFP8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutathione transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_14863</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily. Mu family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01001412">
        <property type="protein sequence ID" value="ODM91816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFP8"/>
    <dbReference type="STRING" id="48709.A0A1D2MFP8"/>
    <dbReference type="OMA" id="KEHMASY"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF222">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="6">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="7">
        <location>
            <begin position="89"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM91816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="243" mass="28551" checksum="D9EA5AC50D5FFD98" modified="2016-11-30" version="1">MGSKPQLVYWDVRGLCEPIRYILRYLNVDFEDKRLPLEAEGSVAWAELKQSEGLDFPNLPYFIDGDLKLSQSLAILRHISRKHNLYGDTEKESATLDMIEQYLIDLQKAVWVVYNDKNFHAIKEDYKKTIPSRLGELEKFMEGKNFILGSKVSGVDFLLYETIEWFRVFAPEVFKEDASLQSLEEFQQRIEAIPQIKEYINSDKYKSWPLFGPVQYFGFSKDPEFKPLPFSYKNWVAKYPLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGS3</accession>
    <name>A0A1D2MGS3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001298">
        <property type="protein sequence ID" value="ODM92200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGS3"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="86" mass="9865" checksum="4EF9A65B7BFE2799" modified="2016-11-30" version="1">MKQKQPTKEKDLSKPKKEKDLIKQLEKKKNRRLARREKKKLDKKLKPGNAVVIKSADILNEYLKEGNNDSSSKESGALQGFKGIMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHN4</accession>
    <name>A0A1D2MHN4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Fibrillin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_14198</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fibrillin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001217">
        <property type="protein sequence ID" value="ODM92485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MHN4"/>
    <dbReference type="OMA" id="DPKCHAG"/>
    <dbReference type="OrthoDB" id="10045365at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001527">
        <property type="term" value="C:microfibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="24"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000005">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000023">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000071">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000804">
        <property type="entry name" value="Fibrillin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000003">
        <property type="entry name" value="fibrillin-1 isoform X1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000068">
        <property type="entry name" value="Latent transforming growth factor beta binding protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000002">
        <property type="entry name" value="Latent-transforming growth factor beta-binding protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000014">
        <property type="entry name" value="Latent-transforming growth factor beta-binding protein 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000017">
        <property type="entry name" value="latent-transforming growth factor beta-binding protein 4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000010">
        <property type="entry name" value="Pro-epidermal growth factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000096">
        <property type="entry name" value="Putative fibrillin 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000653">
        <property type="entry name" value="Putative Fibrillin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000008">
        <property type="entry name" value="Signal peptide, CUB domain, EGF-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="43"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.290.10">
        <property type="entry name" value="TGF-beta binding (TB) domain"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017878">
        <property type="entry name" value="TB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036773">
        <property type="entry name" value="TB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052080">
        <property type="entry name" value="vWF_C/EGF_Fibrillin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47333:SF5">
        <property type="entry name" value="FIBRILLIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47333">
        <property type="entry name" value="VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12661">
        <property type="entry name" value="hEGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00683">
        <property type="entry name" value="TB"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036312">
        <property type="entry name" value="Fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="43"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="44"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57581">
        <property type="entry name" value="TB module/8-cys domain"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="41"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="26"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="37"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51364">
        <property type="entry name" value="TB"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="47"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="90"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="135"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="198"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="240"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="282"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="323"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="365"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="406"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="450"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="518"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="602"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="649"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="709"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="756"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="818"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="860"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="932"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="975"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1058"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1101"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1142"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1183"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1268"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="1320"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1398"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1440"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="1486"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1556"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1598"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1683"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1724"/>
            <end position="1765"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1793"/>
            <end position="1834"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="1839"/>
            <end position="1897"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1909"/>
            <end position="1946"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1951"/>
            <end position="1990"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="1991"/>
            <end position="2031"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="2073"/>
            <end position="2114"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="13">
        <location>
            <begin position="2119"/>
            <end position="2174"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="2185"/>
            <end position="2226"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="2227"/>
            <end position="2267"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="2268"/>
            <end position="2306"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="2307"/>
            <end position="2349"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="2350"/>
            <end position="2389"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="2390"/>
            <end position="2425"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="2354"/>
            <end position="2364"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="2394"/>
            <end position="2404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM92485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2650" mass="286751" checksum="1B727835BDCC9A3C" modified="2016-11-30" version="1">MKKSCMHSSVVLCNRGEGMGHPCEACPDYLDCETGHLKNIHSGQCIDVDECEAIPGVCEGGKCINTPGSFKCECPPGQAPRDGSTGPCEDENECLKPGVCAHGRCINTEQGYYCICDRGFIPSQDRKVCIDARQGNCFTSVLRGICRGKLNVRLTKRDCCCGVNMGKGWGDENDCEMCPSVNTTSHRELCVEPGLLIGVDECGLRPDICGSGRCIDTTDGYKCECNPGYSQRSPMAPCDDIDECRQQTALCQGGRCVNNAGSFTCLCPPGFDVSSDGRFCIDHDECSETGMCANGVCINMDGSFKCQCKDGYILSPTGHACIDLDECYENPRICLSGRCENTPGSYKCSCLNGFTPSVDLAFCVDKDECGETGMCENGRCLNMEGSFKCVCNPGFRLDPTGKHCVDVNECDQHPCQGGRCVNTKGSYKCECLPGFTLGPDGRTCLDTQRDICYAQFRDGLCTGPSNTPVPRSTCCCCTVVLGQPMGWGTPCRSCPVPGSPEFEILCPHGAGMTHNGDDINECAQNPNICVHGTCENLLGTYRCICDHGYQVDPTGRQCLDVNECEIDGVICGGGQCKNTMGSFQCICPTGTQYDPRTQVCQDIDECQDPSQETCSNGQCFNTIGSFECRCDEGYVLDISGRICIDNRKGSCWTKAIAGKCEGNLKKPMLRAECCCSVGKAWGSPCEVCDPRLCECPPGYTKLDGKTCTDINECDLHPGICQGGGTCVNTEGSFTCTCPPGLELEAGGTKCVDNREELCYMQLKHGVCSRPLDGLYLRADCCCTVGRAWGRECLSCPRPGSEAMQQLCPRGMGSSGRRDMNECSMIPGLCENGRCRNTVGSYTCRCNQGFALDEDGIKCIDIDECSIMAGVCGNGTCQNIPGSFTCNCESGYETTMMMQTCMDVDECLRTPGLCRGVVASTHREASDVNVRPDIDECSRTSGICSNGVCENMMGTYQCVCNDGYQQIGSNRAHCEDIDECSVNNGGCDAICINTPGSYSCACSPGFMLLMDGKTCTDADECKDNSRVCNGGKCNNAPGSYDCECTTGLMPSPDGSTCLDVDECRADPGVCGPGHCENTLGGFMCRCDDGFSVRPEIGPNCVDEDECLMGNYVCALNAECVNTEGAYECRCLEGFTGDGSTCRDINECTVNNGGCHADAQCINAEGSFRCACDAGFEGDGNTCQDIDECSNNPNLCENGQCLNHPGSFRCECDMGFMNPDDDDHSCVDIDECGMFHHLCVFGKCENIHGMFRCICNKGYQLDSTGGNCTDINECENPHSCLYGTCINTQGGYTCQCPPSYELTEAGNACVDKRKSQCYLDNGEDFLGVSRGGRRPFTGGRRECARPIGELMTRATCCCSVGTAWGPLCEVCPPPGSDEHNILCAGGNGFRPNEGTVVLEDIDECDEMMHICDHGKCTNTFGSFMCSCNPGYRLDVSKAMCIDINECIEEPGICGVGQCVNDDGSFHCLCPEGFSPLPDQKECVDMRKELCYMEFNTTTLQCNRSMHQPQTRMVCCCSMGAAWGDACLPCPKQFTPDYTTLCGGTPGSVINPMTGQPEEINECAMMPGLCRNGACVDTKQGFHCDCYRGFIYDEASHSCIDDNECSRSPSPCHGNAQCLNIPGSFECRCPEGYRLDHSQRGCLDINECVERQGICSYGECNNFQGSFQCICRNGFQLTPSRDSCIDVDECQRNPTICNNGTCINTLGSYKCICHGGFKLSPNNDCEDMDECQMMLGACRNGRCRNTVGSFTCQCADGYTLSPDGHNCRDVNECEEVPNTCSKPGTCHNIMGSYICNIDECQLNVNLCTDGVCINTDGGFICQCPENYVLSPDGKKCVDVRQDLCYDGLLGGLSVGRPGVCTKARRGYVTRMSCCCTGGKAWGSSCESCPPIGSREFQKLCPQGFGRGDEGEDLDECAIRLDVCDGGECVNTDGSFRCECPQGFVLDSSGNRCIDDNECVSGNACGNGTCFNVEGGFECACAEGFAPGPNQVCEDVDECRERSHQCAFRCHNTLGSYKCACPYGYVLAPDGRHCTDLDECSSQANNCKFMCKNLIGSFMCICPEGYQQIGGGDDCRDINECSTEGGLCHNGRCINTPGSYRCECYDGFESSEDFSKCIDKRQGFCFRQLVGGQCITRDSSNGLSRTTKVDCCCTMGAAWGQRCERCPQPGTTAHKDLCLEAGYSIDGTDIDECSILPDLCKHGSCINTLGSYRCICNKGFKVDASGTHCIDVNECEFTPKVCQHNCENTVGSFICTCPNGYTLSNDGITCKDVDECASGRHGCQHECVNTQGSYKCACSKGFSQVGDQCLDINECSEQHGICPPPGTCINTMGSYKCICPRGFHTDPTGTMCLDADECTDDSRCQHGCQNVVGGYRCACPEGYTQHYYYNQCVDEDECTGGACGSASCQNTIGSYKCQCPDGYQFDNMLLICVQMSSNCIGSPCAFGCISYGQDGFICGCPAGYHRIGQGHCLSTITPPAYGGYDIEDPSLTSEGTDRFISTEGCFSCKVGAASRSGRGRRSISSASSHFYNATVEMGSSRSLSSFQDTHHKELDDQLILMVPMDHTKPRYRILRLQPSLKNMAHMRYLIVSGNEDGALEINHEEEPASLHFRRKIRQPRTYDVEVMGYSRDPKIYQFSRNDPFTLRLRLIITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MI53</accession>
    <name>A0A1D2MI53_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001194">
        <property type="protein sequence ID" value="ODM92592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MI53"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904070" evidence="1">
        <location>
            <begin position="21"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="70" mass="7499" checksum="0DF327F70D91E60E" modified="2016-11-30" version="1">MAKFTIVLLALVVLFAVASAAPMGFGMGIGHGMVSSHHVSHVGHGFMHHPFMWGYPGIIGRGFYPGMMWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIL8</accession>
    <name>A0A1D2MIL8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Angiotensin-converting enzyme-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_14029</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase M2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001178">
        <property type="protein sequence ID" value="ODM92654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIL8"/>
    <dbReference type="STRING" id="48709.A0A1D2MIL8"/>
    <dbReference type="OrthoDB" id="10029630at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008241">
        <property type="term" value="F:peptidyl-dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001548">
        <property type="entry name" value="Peptidase_M2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10514">
        <property type="entry name" value="ANGIOTENSIN-CONVERTING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10514:SF27">
        <property type="entry name" value="ANGIOTENSIN-CONVERTING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01401">
        <property type="entry name" value="Peptidase_M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52011">
        <property type="entry name" value="PEPTIDASE_M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM92654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="13560" checksum="48F08A63629EBC2B" modified="2016-11-30" version="1">MKWISMLVPNTMFQPHTPIPVVQGFVYNCKGVSCSTSAKCDFYQNQEAGAHSNNFRSWLFKNWHVLLEETISESKMDASAILEYFAPLHDYLREYRAKINYPIGWSKDAFEAMVRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MIN4</accession>
    <name>A0A1D2MIN4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_13841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001136">
        <property type="protein sequence ID" value="ODM92839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MIN4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="469" mass="54348" checksum="08977065C14C702A" modified="2016-11-30" version="1">MTDRSEDSNSGRWCILTSPNTNPYLPPEVWAKIFRYLPMSDKLSVANTCPEWDELLTSEKHIALLEKVLPLLNLNQQTILTLREVSKEAKQSVDNILATFANQQESFYFNHEVSTRRRNFNIIIDQLNSAYNFSSFFLDDELRRSALRFLTEVGENRGREDNPFLTRSAEISFTDSERDFATTERMLTLFGHHLWSLTVNIHANLEEQNIENQRHLNVPTGKLPRLLRLVPNLKHLNLAATSARNAVLEQLGPEELPNLEHLGSLSFGDWYNLPTLPLVDMLSVEILNAVLPNLKILNIWYSPRYITLQKLANVNWQLEELRLESLHHVNNWRYLFNAIGNFSQTLILLKLGSGLQSLRLPTSGWEEFLNIFIPLVPVMPHLQVLGLDSTFMQNSKCYWFFESVSKRWGNVRELHVDTALAHEVVILNWRLVYWAFRTLPNLGTILNWSNNPQNFQLTLDYVLTRPDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJX1</accession>
    <name>A0A1D2MJX1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">REST corepressor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_13314</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CoREST family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001009">
        <property type="protein sequence ID" value="ODM93366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJX1"/>
    <dbReference type="STRING" id="48709.A0A1D2MJX1"/>
    <dbReference type="OMA" id="MEFCEDA"/>
    <dbReference type="OrthoDB" id="10064338at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000033">
        <property type="entry name" value="REST corepressor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1240.50:FF:000002">
        <property type="entry name" value="REST corepressor isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000949">
        <property type="entry name" value="ELM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049048">
        <property type="entry name" value="REST_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051066">
        <property type="entry name" value="Trans_reg/Corepressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16089:SF28">
        <property type="entry name" value="REST COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16089">
        <property type="entry name" value="REST COREPRESSOR COREST PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01448">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20878">
        <property type="entry name" value="REST_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01189">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51156">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ELM2" evidence="11">
        <location>
            <begin position="106"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="12">
        <location>
            <begin position="192"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="306"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="12">
        <location>
            <begin position="441"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM93366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="522" mass="59849" checksum="415BB485BF258DA9" modified="2016-11-30" version="1">MADSEEEFERKRKDKMLRVDRTELINISRRLQTNDEVKARRDEWSGNGNGNDRNGGGKSPSPAKPNSWQIWNQGANKHSDGGAENDPSSAHPPVHIDVFQEREGGGGMRVGRDYQAKVPNVIPEAERNVQGENDRALLVWKPTEKLTDDEIESYISMAKEKFQYTGEQALGLLYWHRYDIQRATQDLGNFTPHPEEWTIEDKVLFEQAFQFHGKSFDKIRQMLPDKSMSSLIRYYYNWKKHKNKSSVMDRQVKKLSQEDEDSVPGTNGSGVMSIQNNNISNLHHPHSIGMLQDSFHSESDDEKQISETARCCGNCGVPCTEVYTKENLCNTCFIYWKNTGDSRPLTGPLRRGDKNTLGGLLRQRRSPPKGMNINHDDLSMLARSQPQAENVILQGLEKEVLDMKCRIQTVKQRVELCRRGLPDEGVSHLRPREGLGPSSCRVNSRWTQDELMLAAQGIRRYGKNFQKIAEVIGTKTEVHIKSFYANYRRRYGLENLIQEHQLENADDELDDNMQLIDNNQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MJZ9</accession>
    <name>A0A1D2MJZ9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc finger protein 830</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Coiled-coil domain-containing protein 16</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_13460</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001044">
        <property type="protein sequence ID" value="ODM93222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MJZ9"/>
    <dbReference type="STRING" id="48709.A0A1D2MJZ9"/>
    <dbReference type="OMA" id="YIDFMRE"/>
    <dbReference type="OrthoDB" id="77607at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059039">
        <property type="entry name" value="ZNF380_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040050">
        <property type="entry name" value="ZNF830-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23406">
        <property type="entry name" value="ZNF380_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="16">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="57"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="222"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM93222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="264" mass="30071" checksum="B81DF39B0B0CBAE4" modified="2016-11-30" version="1">MSTKIKLKPKKIESPLAKYNSTGQLFCVLCNAQVKNEIYWTGHINGKQHRDNVLALKQKPPAAGFKRPADPPARSGDKPPPEKIQKQEPKPTPVVIAEQDLAALRNEEEKKKLLNTQVPQVQNVQEDDDADDTPPQAPVPESKSLPAGFFDDPKEDAKARGVKFKNPQDEEWDKFVKEIATEDIKSNEIVGIEQEASAVDRELEQIEEQMVHWQRVIDLEKRAKNRIKQTTSKPMDVDQNEASDDDGDEDLDYTEELDWRNKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKQ1</accession>
    <name>A0A1D2MKQ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_13260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000996">
        <property type="protein sequence ID" value="ODM93424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKQ1"/>
    <dbReference type="STRING" id="48709.A0A1D2MKQ1"/>
    <dbReference type="OMA" id="RHEHVTT"/>
    <dbReference type="OrthoDB" id="9411774at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001397">
        <property type="entry name" value="Datilografo, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF434">
        <property type="entry name" value="FI01124P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="251" mass="29229" checksum="97880AA405423249" modified="2016-11-30" version="1">MGSQVKQVSAKRFPCLFCQKSFVARNLLEVHLNGHTREEPYNCHLCDKTYKSGTGLKQHCPASFQLTHEKNRHLAISHGIGVSVTCPICNKPMSGQYALEAHMRKHTQERPFKCSFCFKTYLNIGSLKRHEGFHTDVKPYICKICGISFTHWHLLETHKGEHNGKLHQCSECSSSFRERCNLLAHIRNVHKNERRFACIVCGKRFQTSSKLRRHTFTHSNEQPFKCDHCGERFKYQESFKSHLKRHSMEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLU1</accession>
    <name>A0A1D2MLU1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000907">
        <property type="protein sequence ID" value="ODM93814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLU1"/>
    <dbReference type="OrthoDB" id="10023921at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="29145" checksum="DAC20BB609EE0358" modified="2016-11-30" version="1">MTTFPFLCELLPGAVPSLVYTSLTLSTPSSSSNSIKNRIFVPKHPIQSLEATTISPSSSSSSIAPIPSGSNNNEMLSSTSVTSSSSSSSSSNGLDPISITTDDPLSQPSPRIFRRSARNFRSIPHPREIVSRLFEEILVCPNHHTRVDKMLRESDSDLGFATRCNFPGVAFFEQYSEHNYSLPLRVDEVVFSQVPRLQRHLVILANSVVNSLKPIFPTETILEWIEQNMWEAWKALDKLEKAGDTLRNIQVCEKTCSESTKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLU5</accession>
    <name>A0A1D2MLU5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Complex I-39kD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">NADH-ubiquinone oxidoreductase 39 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction. Interacts with BLOC1S1. Interacts with SLC2A4. Interacts with CLOCK. Interacts with RAB5IF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I NDUFA9 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000904">
        <property type="protein sequence ID" value="ODM93835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLU5"/>
    <dbReference type="STRING" id="48709.A0A1D2MLU5"/>
    <dbReference type="OMA" id="DMKYDPI"/>
    <dbReference type="OrthoDB" id="275457at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="6">
        <location>
            <begin position="73"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00042000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="416" mass="47758" checksum="AA94A1915E9B4946" modified="2016-11-30" version="1">MAAALSEILRKSPRCQGLVMVTRPCVASAKLSTDATKHQNNSEINKPSIFEPKMYSLKRGTGGRSSFNGVVATVFGATGFLGKYVSNKLGKIGTQIIIPYRGDHYDVLRLRLVGDLGQVLFFPYHLQDEESIRKAMKYSNVVINMVGRDWETMNFKYKDVNVTGARTIARLARECGVKRLIHFSSLNCETPEGLGILPDGSQFLRTKYQGELAVREEFPDATIFRPADIWGQEDRFVKYYAHHWRRFFQWVPLWHRGEKTIKQPVYVSDVAQGVINAIKDPDTAGQTYDLIGPKRYQLGELVDWLFRVMRRDEEWGYRRTDLRWSPMFQMRISATQKFSPSWPIAYLNWDKIERDHITDVPTGNPTLEDLGVTLTDMESRMHWELRPHRAAAYYDEELGEFAPPVPPKTVSANARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLZ4</accession>
    <name>A0A1D2MLZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">39S ribosomal protein L41, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12786</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000894">
        <property type="protein sequence ID" value="ODM93895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MLZ4"/>
    <dbReference type="OrthoDB" id="408933at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019189">
        <property type="entry name" value="Ribosomal_mL41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09809">
        <property type="entry name" value="MRP-L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM93895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="201" mass="22944" checksum="5EABE0647A29DEE9" modified="2016-11-30" version="1">MSSLIAFTRTGSSGTAGTVGGFLFPNLIPCRQISVSSSLYGKRNIRKFFLGNKRGRDYIGKLKWKEKLLPGIQFTVKASGFHYDGVYHKVPEMIPDIIVPDLTDFKLKPYVSYKTADIYQTEFTPENLFESVYKNKIVRDFKNNKLDDQGNPLEPNEMEKLTPEEAWIIAKNPAAISLAKEPKFWECLDQSLIDEDLQRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMY6</accession>
    <name>A0A1D2MMY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000806">
        <property type="protein sequence ID" value="ODM94430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMY6"/>
    <dbReference type="OMA" id="CISPRIG"/>
    <dbReference type="OrthoDB" id="10535344at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="102" mass="11566" checksum="C451739544B0DE43" modified="2016-11-30" version="1">MIGELIIPIFLLILAVVLLLGALKNSAEKIRLWLILWIVFIIICVVFQVFNIWSHQAVNPRTGSSLVGFLLFIYQIWVVYAYLTELRCGPAGLTYCPTQITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN18</accession>
    <name>A0A1D2MN18_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_12244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000805">
        <property type="protein sequence ID" value="ODM94437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN18"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM94437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="19069" checksum="68B4D48704889025" modified="2016-11-30" version="1">MRMGAGVVFRTKSSLVDTGFRLSYTSEPVINEKYEGPDVILNNATESVATQIDLPINSSYSGEIHFSIIVATSNSKVISDENTRLKLTLDEQFNNVDRCRTVARVYKWDKIDFYGEMVEGLVEEWVFCADNHKDFLSDYGLLLVVFWTDGVHVGARGSLSTEMVKVGVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNL2</accession>
    <name>A0A1D2MNL2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphodiesterase</fullName>
            <ecNumber evidence="8">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000769">
        <property type="protein sequence ID" value="ODM94680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MNL2"/>
    <dbReference type="OrthoDB" id="74705at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1300.10:FF:000003">
        <property type="entry name" value="Phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000032">
        <property type="entry name" value="Phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0140">cGMP</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="10">
        <location>
            <begin position="513"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="945"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="590"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="590"/>
            <end position="594"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="630"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="741"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="741"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="794"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1571" mass="176901" checksum="D134DDFB711326CE" modified="2016-11-30" version="1">MRIKASRSLVDSWLLAHSISQPPGIGPSALSGNGGVVTTLVAATGTIAASTVTVVHSSSSGDVSLQQPQKHNRKFWATTPVRKISAQEFEKGGLLKPMVTTTIDGTPTFLSPPTPVGSRCSLVDRKSREELQSLDERELLFELAKDICDELDPRVLTLKILQHVGVLVSADRASLFTVQGKKGCCNRFLVSCLFDVSSQSTLEDMEKKEEIRIPWGSGIVGYVAKSGVTVNIPDAYQDDRFNQDVDAKTGYKTRSLLCMAIKDKRGDCLGVAQVINKRNGLAFTRRDEVVFQNYLQFCAIGLGNAQLYQQSQLENKRNQVLLDLARMIFEEQSTIEHMVYRILTHTLSLMQCQRAQVLLVHEASKGTFSRVFDLDCNDLVDSDAETRRSPFEGRFPINVGISGFVATMGETVNISNVYEDSRFDPSVDTVSDFCHKNILCMPIKNSDGRIIGVIQLINKFDGLPFSMSDENFLEAFAIFCGMGIHNTRMYEKAITAMAKQRVTLEVLSYHATAPLEEAVCLSDAMIPSAQHFRLHAFDFDDEAMTDEDTYKACLRMFMDLDLVKRFNIEYDVLCRWLLSVKKNYRKVLYHNWRHSFNVSQMMFAVLTTTKLWQVLGDIECLGLLIACLSHDLDHRGTNNSFQIKASSALAQLYSTSTMERHHFDQALMILNSQGNQILSHLSSDEYSRVIRVVEDAIIATDLAVYFKNRGAFMELVDNESYDWTRDDHRDLLRGMLMTACDLAAITKPWDVERRIAELVASEFFEQGDLEKQTLNIVPIDMMNREKKDQLPAMQVAFIDSICAPVYEVFAKLSPKLSPLLEGVQINRHNWIQIISQGHILDLEPIKTIESSKMRLLSVVLVSVCLPGILGVDYGVAYAPAPQYSSYNPPAPQYNPAPYSSPPYYPTPQYAPTYQPVYTPTYYETYDTQVDYKEANSTRHCGILPTVHSQYGYVKDRVSFGQYPWQVQILDNYNNYKCAGGLISPRHVITSAYCVDNLDIYSLRVRVGDWDIQSDKNYQEVYKNYELTVCKKHPFYPIPGYYGYDASASYPVVILELYADVDLDQYPHVEPLCIPEYYYLSKSYTQEYSYSYGYGSQYGGGSPQPQPNAAQDKNEEGADKDLECIVLGHQESTLEKIEYQSSSPAPQYGYGYAPPYSYESYEYSRTPRRAKLHKIYSYTPQYSYGYGYTPKIDTWEAEYYYDACHADLGSPIFCLVEGKYEEEQYYAAYPPTPTYTPQYTPQYEPQYSSPPYYSPAPTYTPPYSPAPVYSSPPYYSPAPQYDYPKYKRYAQYSPAPPTYNPPYYSPAPVYSSPPYYEESYKYPIKYAEDLNREYRRAVLYGVVQYPTQCAYGYGSTGNKITATPAKELVAWIENVLHTPASCSSVPTASPRARRLSVLLSSDYKEIYKFHWIFFEAELLSALPSQGDRIMPPAPTTTKMLTASTNGTLLKSHDDFHLDDAVANGKSTAVNGSSQSNGAVKRTGGKQEVAAAGKELDMHGDAKVEIVTGETDQFFVHPPNLQLLRLAFMAATLGVGRQGWCANLLCGGKSHPTNGVGQLCVIAPKFPEHCRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPB5</accession>
    <name>A0A1D2MPB5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000733">
        <property type="protein sequence ID" value="ODM94919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPB5"/>
    <dbReference type="OMA" id="WYELWIV"/>
    <dbReference type="OrthoDB" id="10570159at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="230" mass="25670" checksum="C444E176D2C5E796" modified="2016-11-30" version="1" fragment="single">TMAAPGTDYETKIYCCSNTTKAESKILASFDIFCSVLFLLYSTWFCELLKNRPEEFKNTTIYDNSTLRDFHFLLDLEDQQQNFFVAGLLVWCGWNVALGGTLLFAAEKEKQGLLKVWFGITLLEVLFGVFLVVLALWNMKRRVLISTTTIMVYLYKWYELWIVMGLIRDLHSGSTVFAKGIDDGPNPAFVIESPTPEHDPVYTIEGQGGTGSGPGGGGSTPKCSDALEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPY0</accession>
    <name>A0A1D2MPY0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000703">
        <property type="protein sequence ID" value="ODM95159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPY0"/>
    <dbReference type="OMA" id="EMENCVI"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="69270" checksum="553F40B6AE72CDCA" modified="2016-11-30" version="1">MEPVTTPNPLLLDVVLDNVFPMLDLPTLLNCRLVCKCWCENSGLKTTIREKSSVSLRCIFLHTSTTKENISNYFQPNNGIIYSRYYFEHISYQNTLVSKVFEVMGKTISILQLHLDLNQLKMNQFRELIYERTPNLEELKIYNLSHEEIYYKQLFPELSDPNDLPKLLNLKRLELQETRSPIVTFMTEFMRTLPNLREITLKTDVCSDWEEQAEMWRQNSAIAKSVIEGLQFSEVFKTLKVFKCGKLLPYHVQTLLEMGERGMMLEVLELHVPPKEAEETFTRLLNTQSTSLKQLIMFEQRVPHFRPRRILGHPPTDQDFILKLPVKMEQLELLQFSKNYKAWMVPMKPVDYARQTPKLKTLCLNGYDGFGCISDYFGVSSQATCMVTSLVSHDHVSDSKIANLMFQSFPHLTKLSIRYPSPQFLTALWSSCPRIRDLTLILTDSLVCPYLDDVITGVDTRTIGYYLGRVKSYGQMKRLKEMGSQQKVACSIMNLTGLRRLRITVDHNENDERQALSDATAEFALRRMDQLRLLELYTSHWTLGLTSCVFFSHPCCERLKQDLKLTVIRFSPGDTESQEAALDYENENAVEDNLYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPY5</accession>
    <name>A0A1D2MPY5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000709">
        <property type="protein sequence ID" value="ODM95127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPY5"/>
    <dbReference type="OMA" id="IWNANIM"/>
    <dbReference type="OrthoDB" id="9978031at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.20">
        <property type="entry name" value="2'-5'-oligoadenylate synthetase 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="479" mass="55196" checksum="2C012C4D5C7E993B" modified="2016-11-30" version="1">MSQKNGRKRVLEETDYDLRRFGESLKCHEKYQKDAERLTSKVLQTLRSKSKYKLGKHDFGGSYGKNTDVIDPDLDIVVRVKNCQPPFEKVLNDFEKVLRSHEGYLQIRSGDYKKSKRSLNFFFTNGIPVDLLPAEDVKEDELDDLLGEMEENKQNAYYHGPALVEDQVGFLKSQNSFTHTVVRLSKFCFKSWYLGGESCRGGSAMMELIAVAAAEKELTKKYASEFQALRGVMVMLGNLDTLKLAFSRVDDEDDEHREWERVKPSELHRHNTKWLIPDVVGNRGILNRPCFIIDPANPFQDYLEDKSDEVIGKLKNFACTTRDRLDRLLKESKNNGEDDEFMRKLFRPIPKDLTKENDKSLSLPDDILLTCDERCNSIYNKVKIWNANIMEDLKVRQAVKVLKKNLITVVHSTVKGNPDDVTVDDVTDAVEELIENNLQTDLEDANQWEEHSDQFDVMIKIPYVIRGKGYAVCLSMAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRP2</accession>
    <name>A0A1D2MRP2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450 9e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_10963</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000630">
        <property type="protein sequence ID" value="ODM95713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRP2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRP2"/>
    <dbReference type="OMA" id="DESWRIM"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM95713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="334" mass="38068" checksum="92C474C3FF0DA8CD" modified="2016-11-30" version="1">MRHIYVKDFDHFQDRSTFNASKSDILFKKMLLFLEGARWKGMRSRLSPTFSTGKIKRMFSIFEKSSQRLCDLVKKQVGPNGGDYDICEAYPKYAIDVIASSACGVESKAFEFTEPGGPLSEFETMAGKFQLKIDLAMFFKFMVIMLAPKVAKFFGFEGMQLEPQMYFLSVMKRVMEHRRKTGERHDDFLQLMMDAQQGLLKAEENSKETLEVMMGTEADSIGNAKNSFTSSDELTDEDIVANAVMFLNAGFDTSQSVLIFAAYSLAKEQDVQEKLYNEVKSKMDANGGNLTYDGVLDMNYLDMFVNETLRMFPPAAKTVRRCVKDYQIPNSNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSL2</accession>
    <name>A0A1D2MSL2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vitelline membrane outer layer protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000578">
        <property type="protein sequence ID" value="ODM96109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSL2"/>
    <dbReference type="STRING" id="48709.A0A1D2MSL2"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841:SF0">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03762">
        <property type="entry name" value="VOMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
        <property type="entry name" value="Vitelline membrane outer protein-I (VMO-I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904485" evidence="1">
        <location>
            <begin position="28"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="117"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="588" mass="65860" checksum="FF019CD059C858B4" modified="2016-11-30" version="1">MILHSRSIDYSLIVLAITLSLFKNGITEAPTHFDCITSGASKTGVAKFAFPSNCENYIYCVKGKAYLQKCPPGTAYSETVKDCDLFDTVAACNDDSNSNAIRYNKPIAGEKYEGKDVNDCSLRDSGLYPMLFGDCSEYVFCKSNRAYAKKCPFNLLFDMERLECLMPADAKCWKPTGPTGPNKFFPLHIIEYYPNFEDENEPLVATMANPDGPIPAQKECLYKHRPHAKKFDTTEDGIVLTSPVLKNDGNWLDWKYCEPGTYVNAVGSFRRSKMQNGKTDNAGIISLAVICQHPDQMGKVGEVNTTIFDVAPNSPKTDSQFSRFFHCEDGAAATGFQLNSEPDQGPKDDIGTANVRLICSCGPPAVKPYWIEGVYSVDANRQGEWTKERGCMPRQALCGMQVQMMPYENKVNLAAHDNTGLNNIKMKCCNIPNPVDSCMPIEREVLVATCDNTASSQAQNCEFDGQVGVDYDFANFERSAYFYESTGFTLEHQLAKIQEKMSGSDLHCGMGNCLFQWDNATSIVWKKMVRGLLKTNVVGGWTSEIFQIVGQCGIYMMYTNRFMRMDTDTLNRVRINRDYWDFNQDTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT73</accession>
    <name>A0A1D2MT73_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein piwi</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000610">
        <property type="protein sequence ID" value="ODM95895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT73"/>
    <dbReference type="STRING" id="48709.A0A1D2MT73"/>
    <dbReference type="OMA" id="HISIIFR"/>
    <dbReference type="OrthoDB" id="445936at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034587">
        <property type="term" value="P:piRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02845">
        <property type="entry name" value="PAZ_piwi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="1">
        <location>
            <begin position="28"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="319"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="585" mass="65741" checksum="5C7924B4A12F744B" modified="2016-11-30" version="1" fragment="single">MWYVTSIRHHEDKMLLCVETTHKVLRMDSVLLVIKGLERSFGANQNAFREAVKKELNGTIVMTTYNRKTYHIDDIEFDKSPQSMFERKGEQQTLVDYYRSLTIKDLKQPLLKAKSKQEGLACWEKAADPGDILLVPELCQSTGLTDNMRANFSLMKELSKYLHQAPQEKGPRLDGFNKRMREHPEVRFTRIQVNHHIKSELVNWGMELDGKLVELKGRILAKEVVSFAKGTHQVDDKGDFTMAFRSQQMLTSVNLTTWVIIVPQRDFAGVDNLVRTMTKVAAPLSMAIGNPKQIIKVPDARSGSYLSAMEDALNLKPQMIFVILPNNKAELYNVVKKRLAVDKGVPSQCFLAKNVTSKGLMSIHQGRRSDECQAGRRALDSEASLKSCMFVGFDVYHGAKGSKGGSVGAMVATFSANFTKYFSTTSLFKTNDELCETMLADLIMLCIYACFILNSAATISKRSTASFRSESSCIVTVGEGQLKAVYNIELTKLSEGLMKMYANGGRSPPLLTFIVVSKRVNTRLMMMKMNLQNPPPGTIVDEVVTLPERYDFLLDFLCCRQGTVSPCSYNVLQDENNFDADRIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTZ2</accession>
    <name>A0A1D2MTZ2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein heavy chain, cytoplasmic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Dynein heavy chain, cytosolic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_10275</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Cilium membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000542">
        <property type="protein sequence ID" value="ODM96402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MTZ2"/>
    <dbReference type="OMA" id="NERQMTR"/>
    <dbReference type="OrthoDB" id="14187at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000235">
        <property type="term" value="C:astral microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060170">
        <property type="term" value="C:ciliary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902850">
        <property type="term" value="P:microtubule cytoskeleton organization involved in mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein 1 heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000122">
        <property type="entry name" value="Cytoplasmic dynein 1 heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000002">
        <property type="entry name" value="cytoplasmic dynein 1 heavy chain 1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000996">
        <property type="entry name" value="Cytoplasmic dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000003">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000517">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000003">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000004">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000373">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF13">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="11 17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="1073"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="1377"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="1723"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="2027"/>
            <end position="2193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="2304"/>
            <end position="2376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="2501"/>
            <end position="2556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODM96402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="3700" mass="422158" checksum="B4A731BADA04A086" modified="2016-11-30" version="1">MPHFEDKGNVSLLVAGVRQEGMSLVWESYKLDPYVKKLSEAVFQFAEKVDEVLSVELQTSVDIKSLETSAYSAKTFGEILAKIQKAVDDLSLKQYSNLTKWVQQIDQEVEKRLAVRLESGISAWTKCLEGIVDNEDNDTDTEAKITHKLGGEPEVTRRVEVGDANDSTNFMVYPAVEEVRQQLFQKLFAWQAICTSHPRIQSSRYQVGLEKGQAATYKGLLASMPAGNGTLESSYRAIEAKMTEVTNYVNEWLCYQSLWDLQPDQLYGKLGENITLWLKCLADIKQTRSTFDTAEVRRSFGPVVIEYGKVQSKVSLKYDSWHKDALAKFSALLGSQMTSFHTEVAKSRTDLENQSIETSSTSEAVGLITYVQTLKKKVLEWEDKVKIYKEGQRILERQRFQLPSNWLHIDSVEGEWSSFSEILKRKDSSIQTQVASLQAKILSEDKVVEGKTNTFLAEWEKEKPVKADLKPSEAIRQLTLFETRYTKLKDERGNVSRAKEALEMAGVSSETEDRFVVALEELQDLKGVWSELARIWEQIDEVKETPWLSVQPRTSSKTKAVCIIRTCQTVDSSYAKVNTLIIELKSEALKERHWKSLMKSLRVNWVLSELTLGQVWDVDLQRNEKILRDIIIVAQGEMALEEFLKQVREFWQTFELELVGYQNKCKLIKGWDDLFTKLREHINSVAAMKLSPYFKVFEEDATAWEEKLNRILALFDVWIDVQRRWVYLEGIFLSSQDIKALLPMETSRFQSISTEFLGLMKRVSKSPKILDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVSSVILTEDQGTIIGIASREGEEVKFLNNVVYTDRKVNEWLSGVEREMRFSLATLLAQAVNEVAQFNEKIDQKLFMEWVDRFPAQLVVLAAQIWWCDGVEAAVGNKPKLETVLKRVDNTLTVLADSVLHEQPPLRRKKLEHLINEFVHKRTVTRHLLNIGVTHNKSFEWLRQMRFYFDPNQPDVLKKLSIVMADAKFNYGFEYLGVQERLVQTPLTDKCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWVVLMSLIVSKNECCLPYLSKSKRFKKLSNLRKKEKKKEVSGLQVELVGKNVKVSVEMAIFVTMNPGYAGRSNLPDNLKQLFRSLAMTTPDRQLIAEVMLFSQGFRTAETLAAKVVPFFRLCQQQLSAQSHYDFGLRALKSVLVSAATESKDKGVAVQRGEQIEESKIAENLPEQEILIQSICETMVPKLVAEDILSSFHSCRMYSLELATHQLKWMLLKDQIKAICNDEYLVCGQNAWMEKVLQLYQIQAISHGVMLVGNSGTGKSTAWKVLLKALERLEGTEGVSYVIDPKALSKEALYGYLDANTREWSDGLFTHILRRTGKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLALPPNVRLLFEVQDLKHATMATVSRCGMVWFSHDVLSTEMLFHNFLSRLQNISLDDGEENDQFTQRTTTTKEPGTVDGVSPALRLQQFSASLEHIMDFTKMRALSSLFCMMNEAVRQIHSYNASHQDFPLEADAVDRFMSKSLIYGMLWSFTGDAKLKVRHELGEYVRSITTIPLPPPNATSPIVDYEVTVNGEWSLWSMKVPRTDVETHKVASPDAVVPTLDTVRHESLLATWLAEHKPLVLCGPPGSGKTMTLLSALRALPDMEVVGLNFSSATSPELLLKTFDHYCEYRKTSNGVVLAPIQLGKWLVLFCDEINLPDMDKYGTQRVISFLRQLVEHKCFYRTSDHSIVRLERIQFIYGTFNRAMLKLVPSLVTYAEPLTNAMVEFFLKSQERFTQDMQPHYVYSPREMTRWVRGIYEAIRPLDALSVEGLVRLWAHEALRLFQDRLVWDDERQWTNENIDVVALKHFPTINRHEALERPILYSNWLSKDYVPVDREELREYVKARLQVFYQEELDVPLVLFDEVLDHVLRMDRIFRQPQGHLLLIGVAGSGKTTLSRFVAWINGLQVFQIKVHNKYTAAEFDEDLRSVLRRAGCKGEKICFILDESNVLQSSFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAARDGLMLDSGEELYKWFAGQVMRNLHVVFTMNPSEQGLKDRAATSPALFNRCVLDWFGDWTNTALFQVGRELTMKVDLENTSWRLPLEFPVAFDEINPATLTHRDAVVNAFVFVHLTLHKANKRLAKRGGRTMSITPRHFLDFINHFVKLYNEKRADLEEQQLHLNIGLSKIAETVEQVEEMKKSLELKKKELKEKDELANNKLKEMIGRQQQAEQRKVQSKTLQVDLERQTKEIAKKQEDVTKDLEKVEPAVREAEQAVQGIKKPQLVEVRSMANPPAIVKLALESICLLLGENANDWKAIKTVLMRENFISSIVNFQTDYITDDMRDKMYQRYLSNPDYNFEKVNRASLACGPLVKWAIAQLSYSEALKKVEPLREELRSLQNAAQTNQAEAQQVTDDIERLERQIIGYKEEYALLIAQAQAIKTDLENVQSKVERSMSLLKSLGMEKDRWEGSSEGFKSQMSTILGDTLLSAGFLSYAGYFDQHYRQNLFSTWCEHLTRACVAYRTDLALTEYLSHPDERLRWKENSLPDDDLCTENAIMLKRFNRYPLIIDPSGQATEFLMQEYKDRKLSKHPFGRLVRKNLESALRFGNPLLVQDVESYDPILNPVLNREVRRTGGRVLISLGEQEIDLSPSFVIFLSTRDPTVEFPPDVCSRVTFVNFTSQCLNQVLRAERPDIDQKRSDLLKLQGEFQVRLRHLEKSLLQALNEAKGKILDDDSVITTLENLKHEAAEISKKVEETDIVIREIDSVSQQYMPLAQACSSIYFTLENMHQMHFLYQYSLQFFLDMFNSVLYGNSKLVSVKDHTQRLDIITKDLFKVCSDRVTRGMLHIDRLPFAILLSRIFSKGIFELAFQMFLRFKEGVLPSAKMSGPSFLSQEQIEGMLRLQMKVPAFKNLTSKVDNSDFSTWIRHPTPETNVPILWEETGGGDMAESTRTVYKLLIIQAFRPDRVVAMCALLGEEVLGSDFIPTGDVDLGNIVDTEVTSRTPVLLCAAPGFDASGRVDDLAAHKGQTLVSIAIGSAEGFTQADQAIASAVKSGRWVLLKNVHLAPQWLLQLEKKLHSLQPHATFRLFLTMDIHPKIPVNLLRAGRVFVFEPPPGIKANLLRTFNTVPASRMMKAPNERARLYFLVAWFHAVVQERLRYVPLGWAKHYEFNEADLRVACDTLDAWIDATAMGRTNLPPDKVPWDALKTLLSETIYGGKVDNEFDARLLSSFVHRLFTPRSFESEFLLVANAEGGDISMPDALRRDQFLLWANGLTHRQTPAWLGLPTHAEKVLLTNRGAEMVSKLLKMQVVEDDDDLTAKEQSGDIEGHVGAPAWMRTLKVSAEEWLKLLPEKLTPLRRTADNIKRPLYRFFEREVAAGCNVLETVQRDLNSVILICQGERKQTSYHRMLISELVRGIIPESWGGRYSVPRGCTVINWINDFAVRVEQLITISTTVHLNGAESLECGLEGYSIQKRILQQQDNVLHKRMDGLKLQGAVWKEGLQLSADVLSDMPSVALTWVKVDPNVNIHDGKICLPVYLNSTRDDLLFTVDLKIVNKMDKYSFYERGVAILASTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUG0</accession>
    <name>A0A1D2MUG0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transport and Golgi organization protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10118</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tango6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000526">
        <property type="protein sequence ID" value="ODM96562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUG0"/>
    <dbReference type="OMA" id="DSYVYLM"/>
    <dbReference type="OrthoDB" id="39591at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019451">
        <property type="entry name" value="Rtp1_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019414">
        <property type="entry name" value="Rtp1_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039600">
        <property type="entry name" value="TANGO6/Rtp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057347">
        <property type="entry name" value="TANGO6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20959">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20959:SF1">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10363">
        <property type="entry name" value="RTP1_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10304">
        <property type="entry name" value="RTP1_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25267">
        <property type="entry name" value="TANGO6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TANGO6 N-terminal" evidence="4">
        <location>
            <begin position="83"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase II assembly factor Rtp1 C-terminal" evidence="3">
        <location>
            <begin position="790"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase II assembly factor Rtp1 C-terminal" evidence="2">
        <location>
            <begin position="1016"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1070" mass="119909" checksum="83FDE9BEEDA26001" modified="2016-11-30" version="1">MKGITRTLLAFKFINHTCHELALFTKLTRTPSSEDAISSTSKLNDSPETVLRNITEFCLKKIDFLDSSKDLLHDDGETASYSSWRLTCVILSLLDKLKVCIEAVELLQTDEEKSIHVLSIQSQIIVQKSVELVIGFGILPYLLPGVGVPEKLRKMNPSVRHFLSDARIASPYDQFLRLSHTLEIILICSSSPSLNALIVPKYACDLLAGLLQICKSPIARPKTEVVQHKPGALSAEQYDNVMMIRGTLQTVMTNTFLDIVPKATLINSLFLIGAAEKPRWISNACNELLCTMILSKHGLISVSTTMIESAGRSDTWKLMRIISNLMKNALDKSAKPTCHLNLSSLAEQCLVMVKQNEDTFSKHSESDTAHCGSATNSSKKNGSLSFRLKQGTNNNADLIRVGMFCGLMLMDLDFQLVKSLFWDKLFCHALKLDKCQGQEQAYMSGTGMGGNVECNSVSVSIGNFATSATYGELLLSVLKPMNVSLPLKLLQPVWSLFFQIFVACERYLKKPVQEPNVAAAAEQLHHKLRDVLILLFEIYGSGLGQNLSLSYSNSNSAASANSSVSKGNNFVQAKENVDLCDFCMMLLLNQDSEGIPTLNTFDLQLDSDDDDQTDVKIVRLRQELVSKTSDYNQVFEKHLDISCLCLSSDILKNERMKGIWPQLFRQLLAWGTNKHSYKTNLKNMSFKSDELPTRLDGDSVTVCLNDCQRFITFKLLGELGDEETILEQFTNTDSVEETLSFLELLLSKFTEEACANLEDAFDTSQLVMYALGIIGRREKSRSGTVLKTRFNQAMEDASSPMVPVKGHGILELRKLIEERNAEALENEARVLKVFQDNLPNEDSYVYLMSIQGMAALGLKFHKTVVPALIKEYDFANCDENSECYERSMYQSLSNEEKMETRMKVGEILVKVIQKLGDFAPSYRAPLTNVFFRLMRDEEPLIRASALSNLGELCHLLKFTLGQVLTEVWFCVESILRTEKNVHVRRAALHLLVLLLKGVEKDLTVEGILTDSVVSQHLRDVRRLLTHIEQTEVDLVAKTHCQLALQELQLIVKKLLTPSTSLNYKIRVLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV16</accession>
    <name>A0A1D2MV16_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA delta isomerase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_09950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000508">
        <property type="protein sequence ID" value="ODM96738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV16"/>
    <dbReference type="STRING" id="48709.A0A1D2MV16"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="24376" checksum="5F345002327856F5" modified="2016-11-30" version="1">MSSESQEFLCSFIVNGRLSTRHFSLSSNLQTDNVLFSVENGVRKIVFNRPETKNALRFDMVEKLGNALFESNSDSATKLVTLTGTGDYFTSGNDFSNWDTTHQTIAEMKEKSRKSVLKQLVLGLIECKKPIIALVNGPAIGAGATVVPYCDQTFASDKVYFSTPFTAIGVVPEFCSSYLFPKIMGYSKPLMKAKELIRGPEREKLKQLAAYEMDRINLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV40</accession>
    <name>A0A1D2MV40_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase II subunit RPB4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000490">
        <property type="protein sequence ID" value="ODM96913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV40"/>
    <dbReference type="STRING" id="48709.A0A1D2MV40"/>
    <dbReference type="OMA" id="HRKTQNE"/>
    <dbReference type="OrthoDB" id="2186918at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.40:FF:000010">
        <property type="entry name" value="RNA Polymerase II (B) subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="4">
        <location>
            <begin position="23"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="141" mass="16076" checksum="42B9631FD19B9399" modified="2016-11-30" version="1">MAANATFGNEAQEEDAADLLFPKEFENAEALLISEVSMLLEHRSQQNENSEDEQALSEVFQKTRLYCARFGKLKNNDAITRVRTLLMQKKLHKFELVSLANLCPETAEEAKALIPSLEGRFEDEELRQILDDIHTTISFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MW63</accession>
    <name>A0A1D2MW63_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A</fullName>
            <ecNumber evidence="8">2.1.1.220</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_09763</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine(58) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10365"/>
            <dbReference type="Rhea" id="RHEA-COMP:10366"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74491"/>
            <dbReference type="EC" id="2.1.1.220"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an adenosine in mRNA + S-adenosyl-L-methionine = an N(1)-methyladenosine in mRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:55392"/>
            <dbReference type="Rhea" id="RHEA-COMP:12414"/>
            <dbReference type="Rhea" id="RHEA-COMP:12415"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74491"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="8"/>
    <dbReference type="EMBL" id="LJIJ01000489">
        <property type="protein sequence ID" value="ODM96915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MW63"/>
    <dbReference type="STRING" id="48709.A0A1D2MW63"/>
    <dbReference type="OMA" id="PCIEQSL"/>
    <dbReference type="OrthoDB" id="1925287at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160107">
        <property type="term" value="F:tRNA (adenine(58)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049470">
        <property type="entry name" value="TRM61_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF2">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017269">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 8 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="10">
        <location>
            <begin position="72"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="122"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR017269-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="308" mass="34776" checksum="28A3B348F408953F" modified="2016-11-30" version="1">MSFIERNPIIKEGDTVILFLSVNNHYPIEVTKYKKNKSGNYVENKFQTIYGHFDVMELVGKKYGTKFHLPRGWAYVLHPTCELWTKTLPHRTQIIYTPDISLIIFGLDLAPGSIVIEAGTGSGSLSHAFIRTVYPTGHLYTFDFHEKRADQAREEFQKHGLNSWVTVGHRDVISDGFDVEKPADAVFLDLPKPWEVVPHVQRSLKRGGKLCTFSPCIEQVQKTVEALKRSGEFVMIKTQEVLQRSNSIQYRILTSLDFSLDEAESASGKLVPIKKEQCKFRTLIPPPQSAGHTGYITFATFVPGVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWD4</accession>
    <name>A0A1D2MWD4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Histone deacetylase complex subunit SAP18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_09303</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the tethering of the SIN3 complex to core histone proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SAP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000449">
        <property type="protein sequence ID" value="ODM97370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWD4"/>
    <dbReference type="STRING" id="48709.A0A1D2MWD4"/>
    <dbReference type="OMA" id="TYRMREI"/>
    <dbReference type="OrthoDB" id="440566at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.550:FF:000001">
        <property type="entry name" value="Histone deacetylase complex subunit SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.550">
        <property type="entry name" value="ASAP complex, SAP18 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017250">
        <property type="entry name" value="Hist_deAcase_cplx_SAP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010516">
        <property type="entry name" value="SAP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042534">
        <property type="entry name" value="SAP18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082:SF0">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06487">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037637">
        <property type="entry name" value="HDAC_SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR037637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM97370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="151" mass="17008" checksum="51B9D912790B8C74" modified="2016-11-30" version="1">MATLESVIVEDVNKETEKAIDREKTCPLLLRVFCSTGRHNSLQEYSNGSVPANELQIYTWIDATLKEISGLVKEVNPDARRHGTVFDFSLVYPDKFRGYRARSVGTTVSGQKTPDDNKTLSQLRFTIGDYLDIAITPPSRVIPMRRPGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWR6</accession>
    <name>A0A1D2MWR6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000447">
        <property type="protein sequence ID" value="ODM97398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWR6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="23627" checksum="0AC0529D3CA2C5A8" modified="2016-11-30" version="1">MALNMTNFTEIDSIIPLVELEEEEDEEPVYIGFIESSLAKMIPKFFKAIVTLLMCGFLLGLTFFLITLWKRGCRRHSKLEGEAETNGAPLHSVVVTPPKDEDGDVVGSKSEIPAGSSQNKSKHIKVPKHSLMRRASGPFGSEALSFVGEQYSMKDLEKEKHHFIHPHQYPRSGFHSSSSAHSADVHGNDAPVENEEGNTTKSKWNCFRGNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXI3</accession>
    <name>A0A1D2MXI3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter G family member 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000420">
        <property type="protein sequence ID" value="ODM97678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXI3"/>
    <dbReference type="STRING" id="48709.A0A1D2MXI3"/>
    <dbReference type="OMA" id="NEMAITH"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038:SF3">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 20 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43038">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="8"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="510" mass="57027" checksum="D7931BC1C330168F" modified="2016-11-30" version="1">MHDLADATWDAGSISILGSPPFLKRCEFDSKKLGYMPQDLALQPLLTIQEVLMLYGRLYGMSMHDILSRLTFLQSFLQLPDKHRTIANLSGGQARRCSLAVSLLHSPDLLILDEPTVGLKEIYIVGLDPCLRQNIWEHLESLVDNLQVTCILSTHYIDEARRSHKIGLMRNGRIIAEESPSNLIERYKTTSLDSIVLQICKRDAATKKARSQSNSSSIEELSSSPDNASKVFRVRGKLAKTKEQEQVVMNEDGKGVTFLSFSDFSKSSSNEHFTSFSKGLIGTGNKLTEKCMHTSLGIYRRLQGLIWATYMSSFRHPAFLWLTFILPLFSTALVQIVFGTKLHDLKFGIVDYDGSFHNVSFQDVQANCLESKFGQLYLSKISSGSLTLIPFVDEAHALQAVQMGDTWGFLSIPFNYTSNMQQRMLARQFSTNETLVGSIIGIHMDMSSYLGSLLILKKLSTAYETFLKELGTSCGLPAKELEIPLHYKPVYADTEGSTYAHHIVPGLILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYE6</accession>
    <name>A0A1D2MYE6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucuronosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_08665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132367"/>
            <dbReference type="ChEBI" id="CHEBI:132368"/>
            <dbReference type="EC" id="2.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.17" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000389">
        <property type="protein sequence ID" value="ODM98018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYE6"/>
    <dbReference type="OMA" id="TNTHYSE"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000021">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM98018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="448" mass="51665" checksum="E01AC04D293C2408" modified="2016-11-30" version="1">MLMRLEYGHRPLLLRLTYQLPKIGVDMCDKILGDPKIMKHFSETNYDVIVIDALFNECAYGLAYKMKAKTIVFGTSHPLAWMADALGYPSESWWLPEVHFSFDLPLNFVNRVWATLSIFYFNTIRHLAFPKLEAVLREKLEIPDMPSIPDMMANTSLMLTNTHYSEELPRALPPNVVSVGGMNCKDKSELKPIPKEIEEFINAGGEEGFILVSFGTGANITAAPEEIQTKFFKAFENTKIRFVWKWDGKRHPSIPANVMTVSWIQQQDILAHPKIRGFITHGGLLSMHESIFHQVPMIVFPVFAEQDYNGERLQRTGRGITLEITSFTQEQLEDAIHKLLYDQSYKKNVVEVSKRFMDRPQTPLETATWWVEYVIRHEDTSFMRPLAASLTWYQRRLLDVYAFLLVILISLLYLSVKFFKFIAGIALRKLSTEAKECDINRNVKVKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYX8</accession>
    <name>A0A1D2MYX8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000389">
        <property type="protein sequence ID" value="ODM98014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYX8"/>
    <dbReference type="OMA" id="EAYNIYY"/>
    <dbReference type="OrthoDB" id="10663724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="25576" checksum="7C7C34BFF05722B8" modified="2016-11-30" version="1">MTVSQGLFRIISCLSIVFGVGVLAVSGTLLNQALRYQEIFGYAGYGVNGFGLGGGPFYGNSHYGGGGFGGGLPGFGYGSVATEAYNIYYTSYRIVAVAAVGIVVGLVQILMSIMLCFTGERSVKGITATYICVSFVVLLALVAIFALAIYYQAIYTLYHYHTEQLPDGYNYHFNPEGQAFCAVTGIDVCFLLASMVGAVILAKKFDSYDGHETWTVHRASPSAVSDRSERGYIKAGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZU7</accession>
    <name>A0A1D2MZU7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Wings apart-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000362">
        <property type="protein sequence ID" value="ODM98344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZU7"/>
    <dbReference type="STRING" id="48709.A0A1D2MZU7"/>
    <dbReference type="OrthoDB" id="78088at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012502">
        <property type="entry name" value="WAPL_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51271">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904801" evidence="1">
        <location>
            <begin position="26"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="WAPL" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="91" mass="10055" checksum="5B435E6CF5A85E00" modified="2016-11-30" version="1">MENSLIAAYISLLLAYLIMDNPTAANQVRNSMPNGQYLPLMIFLKKLFNFMSITSSASGSIRGLKATAIALRFFAQADPKSDEELKKLIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZX5</accession>
    <name>A0A1D2MZX5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_08104</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000341">
        <property type="protein sequence ID" value="ODM98572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZX5"/>
    <dbReference type="STRING" id="48709.A0A1D2MZX5"/>
    <dbReference type="OMA" id="LSMIVWN"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF17">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM98572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="283" mass="33821" checksum="1B37035BCD77598A" modified="2016-11-30" version="1">MINITGNSDTFVDVYPIRNPEYLHVYEWENIELTTLRKWVGRNWKLSVYASAIYVVLIYCGQSWMKNRPAYDLRKWLTSWNIILAIFSFIGFLRTCPELFHVLTQPYGFYTSVCTRRGHNAATACWGFLMTMSKSLELGDTAFIVLRKQPLRFLHWYHHVTVFIYTWVTYEDYEPSLRWFMTMNMFVHAVMYTYYALKAMKIRVPRNWAMLVTVLQLSQMVVGVYINVYSLWIKRNGMDCVRRHEVIQLALTMYASYFVLFANFFYNSYLKHSTSLLLRKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N074</accession>
    <name>A0A1D2N074_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_08217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000352">
        <property type="protein sequence ID" value="ODM98464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N074"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="29257" checksum="2F7831F01C73D355" modified="2016-11-30" version="1" fragment="single">VILHCGKSPLNLSGAVIRFWTECLKFEVVGWAMKESEVLDKDVEHLLAQRFRWHACLRRMRRKSKFKPLLNGEDPYVDLSYGSTQELLERMPKGQELNKGTGHERLMLTCKTEEMKVISGLVQTLGLLHGGKESKKSFQLVPGRLDLIGIVAHDPNGLEVCYYSDKEVRLLTFNQLDPNEHLRRRISAYKKKVSEKKRGSRGRFTLVLCVAGRSIEMTTHRISQDITLLKVFLKVRYQLQLSFKESTKKLFLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1P2</accession>
    <name>A0A1D2N1P2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="9">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_07497</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="9"/>
    <dbReference type="EMBL" id="LJIJ01000294">
        <property type="protein sequence ID" value="ODM99203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1P2"/>
    <dbReference type="STRING" id="48709.A0A1D2N1P2"/>
    <dbReference type="OMA" id="VWICMEM"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043068">
        <property type="term" value="P:positive regulation of programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06618">
        <property type="entry name" value="PKc_MKK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000040">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000432">
        <property type="entry name" value="mitogen-activated protein kinase kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052468">
        <property type="entry name" value="Dual_spec_MAPK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47238:SF2">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE HEMIPTEROUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47238">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="73"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="374"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM99203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="520" mass="58809" checksum="FB53CAB23B2B6C78" modified="2016-11-30" version="1">MARRPGLTLNPPLNFGGDIASRRKNLGLNFANLADQRLTREQEETERKFREVDNRNGHITINGQTYKTTIEDMEHLGELGSGTCGQVVRMRHKPSNHVVAVKQMRRSGNNDENKRIIMDLEVVLRSHDCQYIVKCLGYFITDSDVWICMEMMSTCMDKLLKRLKQPIPEIIVGKVAMATVKALHYLKEKHDVIHRDVKPSNILLDELGNVKLCDFGISGRLVDSKAKTRQAGCTAYMAPERIDPPNKHSPTYDIRADVWSVGITMVELATGKFPYENCQTDFEVMTKILNYDPPRLSDKFSLEFRSFVEICLKKNFQERPKYKQLLEHPFIKKSEQTTVNLQTWLDVVSGDRRMYYPTSSFSFPSSNLRHSGRFYRSSTNPSSNYPSSSPSPGSSRSRYEDFALPNSPRAGTRADFHVLHSDSSSSLKTPSTPGTPSPNAPPDPPPRRSLQTPTNSSSSSSVNNLSSPSPTSISMANSSPSPDCPPPPVRRYFCTRLFFTPEPTRKRFFEFSPNGQNYPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1Z7</accession>
    <name>A0A1D2N1Z7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07418</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000290">
        <property type="protein sequence ID" value="ODM99260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1Z7"/>
    <dbReference type="STRING" id="48709.A0A1D2N1Z7"/>
    <dbReference type="OrthoDB" id="413313at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004245">
        <property type="entry name" value="DUF229"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974:SF1">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02995">
        <property type="entry name" value="DUF229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="132" mass="15634" checksum="3B4B051AA03967AF" modified="2016-11-30" version="1">MSDMNMSQSFARMWHVAAALTSRSENETKSTCLKNRVFDECPFVWKNYSERGYLTSFGEDSGKEGGIFVTYWKGFSKPPTDFYFRPYGVFTEEKLRKDWTDVCYGPRLAWEVLLNYAQKLAYIMNKEDQRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2Q1</accession>
    <name>A0A1D2N2Q1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000275">
        <property type="protein sequence ID" value="ODM99511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2Q1"/>
    <dbReference type="STRING" id="48709.A0A1D2N2Q1"/>
    <dbReference type="OrthoDB" id="443401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="2">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="135"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="532" mass="59011" checksum="364C6262E19FD0CD" modified="2016-11-30" version="1">MMDLSDESLDSFLNNNDESSVSQNPAMIVEHTESFQAWLSQVLKPLCDADPGALAKYVLALIKKDKSEKELRQSMIDQLDVFLQSETKPFVDKLFEALNNKEYLNAKQEPLQAKPESNEKANNSEVASGVKADKSSPASETEPTSSTSGPTAAVNSSTHSSSSGNEGSSKKGSNTLSVTPSALLNAGSTEASSHHNDSTGNKDDSKSRRDRRDDDRDKRRKRSRTDRDNRRTSRSRSTDRNKRSRSPRLERDRERDRDRNDRLRHRPRKSPPPRRYERDVWDRRRSRSPMRNRSASPRNRSRTPPRYRRPFNSSRSRSRSPIVRDRSRSRSRSRSPANKDKKDSLLPLPLGHSEGDQASKEISDKPLVQSVVVRPGAQQSENSDMKPGYNAVPQAPGVTGNRCRDFDEKGLCMRGELCPFDHGKDPVVLEDIVVPASGGGGNYGARGIVPGSGPGYTAPLVRPSIIGEYYPDSPSIEAPVGWGPGAPPFRPRHMARGRGGLLLRPQAMGPYPVPGQRQLISVPVVGVHQPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2Q9</accession>
    <name>A0A1D2N2Q9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000271">
        <property type="protein sequence ID" value="ODM99548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2Q9"/>
    <dbReference type="STRING" id="48709.A0A1D2N2Q9"/>
    <dbReference type="OMA" id="YPMRILR"/>
    <dbReference type="OrthoDB" id="514167at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019265">
        <property type="entry name" value="RTRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15924">
        <property type="entry name" value="CLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10036">
        <property type="entry name" value="RLL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="250" mass="28275" checksum="0009862BEC334E9A" modified="2016-11-30" version="1">MFRRKLQALDYPTTDGYQPDDESKFRELIVWLEDQKIRHYVVEQRTALRQTTSPTWRQALNKYLQDLELGGMVDTSTNSEISDVLLGMGIRYDYCDNVEKFSKASSDLVKAEQRQAPKIVAANPLDKLDFSSPDFISGVNTLADQLKVAKHANHLVTLEACAALVKTRYSKEAQKSGLHKQKTGNPFPFQEVDQSFDCGDYVLNHAAKILRLLFICDIRDLQTKINECIVAVQTVTANPKTDTRLGKVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3V8</accession>
    <name>A0A1D2N3V8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Janus kinase and microtubule-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000243">
        <property type="protein sequence ID" value="ODM99966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3V8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="208" mass="22857" checksum="DEAEE686FB4386FA" modified="2016-11-30" version="1" fragment="single">FFFQCGSSGLLETLPEAESEEEEFESISATVGKEDGLYRITRSPLVSSASPSSSSSSSSELSPQAEFPPEFTSLLQPSINGGKLEVAKSIEDFGMLQQCEVENQKISVLESIIRQLRDELKECKDQNELLEFRLLEMQELSASPRPHQTDGDAEDEEEDDVEPKLIVADSDRNPDTSKGVVACLPGSVIHILIVGTKLLSGYAKRFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N586</accession>
    <name>A0A1D2N586_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein msta, isoform B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000207">
        <property type="protein sequence ID" value="ODN00428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N586"/>
    <dbReference type="STRING" id="48709.A0A1D2N586"/>
    <dbReference type="OrthoDB" id="5952526at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="90"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="377" mass="41151" checksum="722F33DD7672E1AA" modified="2016-11-30" version="1">MTQTSDDSSTNSSSSATSTVIMDHHHGTSSVAAKTEEPKETSGEAVVVVVADAPVETVASSVADSTTTDNCVPEMDTNGETSTFSKAPQCAICSEPCICYCKSCKRVSYCSKEHQKRHWKQHRPECFPVAVQVNSVFGSSLVVTRDIKRGEVILREKPLVSGPLLCFSNDEDDRPYDYYCTAPRLDSESEKIFSVCLACHKILLDDASSSSSSSPAPTSCSKCGWPVCMECEKNPTHADQECKIFAESHLKPAALCDKVAQYLCVSLVRLLLHKNRDPTKWAQFMDVLNKQAPMKDGLNSHAQAKTSTARSSDLITKSLGSIIQDFSVTDVEIDQIVRTLRTSAFITDNVGNYINGLGLGPTINSESLYSPLKRRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5Y0</accession>
    <name>A0A1D2N5Y0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA repair protein REV1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000196">
        <property type="protein sequence ID" value="ODN00632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5Y0"/>
    <dbReference type="STRING" id="48709.A0A1D2N5Y0"/>
    <dbReference type="OrthoDB" id="6774401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="94"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="144" mass="15633" checksum="169F2A68597F0BAE" modified="2016-11-30" version="1" fragment="single">MSLLKMLPRPPSTMMEVNNSGKNGVQTADGSATNGTTNGTMSPSNNKVISGRRRFGENGFEEQGGYMAVKKAKLDNQFNCSTRVYGAGETGDSDALDIFTGVSIYINGYTNPPEPELRELFIRHGGTFHPYNSSRTKFVVATNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6I8</accession>
    <name>A0A1D2N6I8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tektin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the tektin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000183">
        <property type="protein sequence ID" value="ODN00880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6I8"/>
    <dbReference type="STRING" id="48709.A0A1D2N6I8"/>
    <dbReference type="OMA" id="CMEPISG"/>
    <dbReference type="OrthoDB" id="9886517at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048256">
        <property type="entry name" value="Tektin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000435">
        <property type="entry name" value="Tektins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19960">
        <property type="entry name" value="TEKTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19960:SF11">
        <property type="entry name" value="TEKTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03148">
        <property type="entry name" value="Tektin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00511">
        <property type="entry name" value="TEKTIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="519" mass="59252" checksum="E890AD65F3567190" modified="2016-11-30" version="1">MYCMNACNLPYSDVNKIDQGPRTKACGWTGECRGEGWISKTDRCSRPGVDSLLRTLPWRHALVQRPPETSVYSGMSKEYCLYDSGYAGDGCPTEPLKFPNLVTGFNVNAAHASRTALYTRYSPSDWQANNAMLYNGTDCTRNTAELVRAEALRLVRETDDKSSRGQMDSGKKLGERLTDINYWKQEIMKELDLKVHESHKLLETRQTLERMIKELDGPLHIAQENLYARESRQGVDLVHDAAEQALLCEIETIRNWQKKLCQQLDGINTHLAQGRASRHELERDLQRKEQAYQIDTGAAQLNNNSKDISFHSGIEKVDPTVSIPETWSGFTEALLKRSKLERATAQKVHAAIDNLLVQAANECWSAWNNSNNALTLRVAELLDAKNKITCHLSKVQQELYDMEKHMEIIRKSIEDKAPSLKVAQTRLERRTHRPDIELCRDEAQFRLVSEIQDINETLEQLQRKLVEVEAAHQQLLKTKACLEHDLKIKANSLFIDREKCLGLRKSFPISSFVTQRQTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6W7</accession>
    <name>A0A1D2N6W7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000176">
        <property type="protein sequence ID" value="ODN01013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6W7"/>
    <dbReference type="OMA" id="QAVQYGP"/>
    <dbReference type="OrthoDB" id="8197587at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905132" evidence="1">
        <location>
            <begin position="19"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="265" mass="27291" checksum="F11D6C925EB3D70B" modified="2016-11-30" version="1">MNSFAFVILSLTVSSAFAGAPAVLSSPAVLSAGYGPPAVQAVQYGPPAVQAVQYGPPAVQAVQYGPPAVQAVQYGPPAVQVQAVQAVAVKTAPVGRLIQRVSYTPPVFAHPVSPAFAYPAPTLAVAQPVLRQVVAQPVVHQVVAAPTRLVAQPVQHVVAAPAIQRVAVAPAPVAYAPAPVVHQVAAPVRVVAQPLVQHFQQYQPQYVAAPAPVAVQHQIQHQVFAAPVQHQVLATPVHHQVIAAPAVHHVAAAPAYATGIHGLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7N7</accession>
    <name>A0A1D2N7N7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Prolyl 4-hydroxylase subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_05403</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000163">
        <property type="protein sequence ID" value="ODN01274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7N7"/>
    <dbReference type="STRING" id="48709.A0A1D2N7N7"/>
    <dbReference type="OMA" id="ITNKWIR"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000011">
        <property type="entry name" value="Prolyl alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF244">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="302"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN01274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="441" mass="50696" checksum="F316E5B2B9F3398B" modified="2016-11-30" version="1">MVYYLHFLSDLAGEIIKKGEKLPSFEDFIGGSMALVGLQDTYALNLSEIIHGDLSTENAVQKSPYELSARDCLFLGKAAFNKGLYDRAVGWLEMALSRAKEEYEDETLLIPTATKEEILPFLETTRRVHDEVLEKRGPYGETWQTFEKPINGKLAKMRKYQKIKRYQPKIMVPLTPVEENENFKALCRGENLRSPKLDAPLRCRYLRRPNSVSILKAYKVEEMSLDPYIAIYHDFMSEYEMGYFKEHSTSRLKRSLHQGRDGRYIATDIRTSKQAWLNKDDGPLIDKISARIGDATGLEVFPENEASEIYQVANYGMAGRYSPHTDYITGDDHLHNPLELVRGNRIATFMVYLEDVPAGGSTVFPLIGVQVKPRKGAAVFWWNLRTDGRGDPWTRHAGCSVLYGNKWITNKWIRYHHQFRRIPCVKEPDNERTASFQTLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7T8</accession>
    <name>A0A1D2N7T8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000175">
        <property type="protein sequence ID" value="ODN01036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7T8"/>
    <dbReference type="OMA" id="DCANEFR"/>
    <dbReference type="OrthoDB" id="10605187at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905173" evidence="2">
        <location>
            <begin position="33"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="662" mass="75644" checksum="EED101FC12CF8C09" modified="2016-11-30" version="1">MNHHKYNIKDGKISVMILLALISFLMMSVVHCSDLNLQQSPLLDCNSETAFLQVHFKDGEPAYFRNWECPDGVWAEEMYQNREATCVCVKGAYAIASELCDEDFKILTGDNHCFDIKGQTIRKFIPLTGKSGLAGRANTVFRKDAPYFARLMSSTPTTSVAEPMHYVFRMNDPNEFTAYAKLSNGKAAKLKCYSGQPPSGKSSEPLIQIAKLPDCANEFRGPKPWCEDGALSGTYEWELSVGQSWSPKGGVGQPGSKDSCSPNGGNRQTPPRRHRKKRASGKSSPSVKQPDEPEPTCNSFDEAVMEAEEYDTSSDHFYQVDMIDQKQIFQPSSYHQKLVFEQNKRIGHQLRKFYLAKEGVFKTPRFETAEEFPEYEYIKLAKRIFVKICPGAALHVLNFLIRTFRLLYIDSSKNYPYPEKYNDQIDARITAALKQCATDADNQEIYFYENKTCPDMGVYATNQSTMTFFYGSNMTMPGSALYNSSMDAAVELIWKLTMVVHYYCLQPGQFVSFTDHSYFFVKLESILKNPLILFRWYYPGQFNQLLEFFLMSYDLRKFTQAVDQCVATVITPSNFTDYMLARPAEMLGWSAQSASKEKKLPHSGKSLIVDKPASRKRRFYLQDDMWNKQAYCMHSTDAPYKEVRTGTFLSCKKKPIWFDNTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8C9</accession>
    <name>A0A1D2N8C9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Smoothened</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_05155</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor Fz/Smo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000148">
        <property type="protein sequence ID" value="ODN01519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8C9"/>
    <dbReference type="STRING" id="48709.A0A1D2N8C9"/>
    <dbReference type="OMA" id="HCEPLRY"/>
    <dbReference type="OrthoDB" id="10064659at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005113">
        <property type="term" value="F:patched binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007417">
        <property type="term" value="P:central nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071679">
        <property type="term" value="P:commissural neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007389">
        <property type="term" value="P:pattern specification process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007224">
        <property type="term" value="P:smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015526">
        <property type="entry name" value="Frizzled/SFRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000539">
        <property type="entry name" value="Frizzled/Smoothened_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020067">
        <property type="entry name" value="Frizzled_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309">
        <property type="entry name" value="FRIZZLED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309:SF35">
        <property type="entry name" value="PROTEIN SMOOTHENED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01534">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01392">
        <property type="entry name" value="Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00489">
        <property type="entry name" value="FRIZZLED"/>
    </dbReference>
    <dbReference type="SMART" id="SM00063">
        <property type="entry name" value="FRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01330">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63501">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50038">
        <property type="entry name" value="FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905202" evidence="12">
        <location>
            <begin position="19"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="294"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="489"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="13">
        <location>
            <begin position="39"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="14">
        <location>
            <begin position="209"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="790"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="803"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN01519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="841" mass="94756" checksum="E9746E0F54B1929B" modified="2016-11-30" version="1">MGVHILLLSLLTLSVTESVRNNGPSGAFGESPMDNCRRKASKPCQAMQFSTCFGAKLPYAFTSSDLVNENFTQQQIQHEMKLWEGLRSVPRCWAVIQPLLCSVYMPKCQDDYIELPPQELCRITKNPCRVIEQAMKEWPSILKCEDNFKFPSGCKMSTDISELRFNKSGSCMEPMKEVESNFNYYEGFEGCALNCSNPLYSKEEHETVSRLIKYLGILTLCANGFVLATFMIDWKSAKVYPSVILFWVNLWYFFATIGWMVQFLPNTKEDIVCRKDTTIRRNEPDSGENIFCPMIFFMIYFGSMSALSWLSVFAYVWFLTCNAVGRIRERIDKKKLYFNVFAFLFPLVLTIICFSVGKVDGSSIAGICFVGINDSSARIALLIAPIGIACGLMMFYFWRGIYRLLSVSLSSSDFISEKGRAEIKSNATRVAIFSLALLGIVISSLVFQFKLMSAKPVWEKSLKDYFFCQLKLLDVAECELTEKADVSLVVGNVVVFFLGGLLMSSWAWTSASLRTWTRYVKRRCDSDESDAAQPHMQKHRLISQAFSKRHQLPAKGRLSLSLQSTHDDPMGFNKLLDPTHLCKNGDMEQSQQLNHTGTDADDINSEWAAALPHLLSRRGALVPPHSSNSVSCVSEDSRRPSCDSNMSELAARNLQSSGSIYDRSVYKKSRRDHWFRMSKRSRSGKVWNYPWRRGNGGSSSSLESNGGSQILPAITALIDKKLKFNGEEPHGTQVQNNLQPALKSPSKIYMMNGETQTSFEKLPTFPEAGKQKFSNTLSVDKATQSSLVSLHEIGTQTKKSATKKKEKDKKDKSKKDGKDTDCQTDKNLSEEDPVLKLLSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N955</accession>
    <name>A0A1D2N955_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dynamin GTPase</fullName>
            <ecNumber evidence="3">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_04901</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000139">
        <property type="protein sequence ID" value="ODN01790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N955"/>
    <dbReference type="STRING" id="48709.A0A1D2N955"/>
    <dbReference type="OMA" id="CAYINTN"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1240:FF:000001">
        <property type="entry name" value="Dynamin 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000172">
        <property type="entry name" value="Dynamin-1-like protein isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="16">
        <location>
            <begin position="37"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="15">
        <location>
            <begin position="645"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="593"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN01790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="737" mass="82399" checksum="984E9E65773371B0" modified="2016-11-30" version="1">MTKPCDMSRDTKIERMEALIPIINKLQDVFNTIGTDSIQLPQIVVVGAQSSGKSSVLEALVGRSFLPRGTGIVTRCPAILQLIYSPKEDREHRTSLEGTMDVEEWARFLHKPDRVFTNFDDVREEIERETDHKAGTNKGICSEPISLKIYSTKVVNLTVVDLPGIVKVPAGDQPEDIEDQINNLILSYIRNPNSIILAVSSANNDMATSESLKLAKEADPEGRRTLAVVTKLDLMDAGTDAVDVLCGRVVPVKLGIIGVVNRSQLDIQNKKSIEDAINDEAAYLQRKYPTLASRNGTPYLAKTLNRLLMHHIRDCLPELKTRVNVMISQFQTVLQSYGEDVKDKSQTLLQIITKFASAYNATINGTSRNIETTELCGGARICYIFHETFGSTLISIDPVSGLSKLDILTAIRNATGPRPALFVPEVTFELLVKRQIRRLEEPSLRCVELVHEEMQRIIQHCGTEVQQEMLRFPKVHENIIEVVTQLLRRRLPKTNEMVENLVSIELAYINTKHPDFHRETDSLLRASDHSVVNEQEKKRQQRPQMVPSSLHAITNGELEPPGPGAAKNWFGNVIGKSGDNSPMHNQMPGMPQQALMNGSDSNGPIGGMGDGPQKPPSPRKHVNLLQASDASTAGYQLSEKEMRDCKVIEQLIKSYFSIVRKSIQDSVPKAVMHFLVNYVQDNLQSELVSQLYKPDQIEELLAESEHIAQRRKEAADMLKALQKASQIISEIRETHLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9E2</accession>
    <name>A0A1D2N9E2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000135">
        <property type="protein sequence ID" value="ODN01883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9E2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905248" evidence="2">
        <location>
            <begin position="19"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="224" mass="24466" checksum="CD686030F6C9F35F" modified="2016-11-30" version="1">MKLKLTILFSTVLTSVLSAPHPVPQNAPAPGPFAAIGGLIQRLQSSFYEGSASIRQPQPSAKAQNLGNETLVRLQLPSSASSKPSTTTTTTTTTTTPRPVTNAFDSINAILDNLNRPSNNNNNNNNNNIDNNNLFGNPQPNLIDLLFTTTTPAPTTRSPFDLDGVGQGINAFLQAFIKTNIQKIFRQPGQDQQQTQQQDIRARSDSPPSIVDTFFNTLFRKRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9S2</accession>
    <name>A0A1D2N9S2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000130">
        <property type="protein sequence ID" value="ODN02001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9S2"/>
    <dbReference type="STRING" id="48709.A0A1D2N9S2"/>
    <dbReference type="OrthoDB" id="1552at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000004">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF10">
        <property type="entry name" value="SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp fold succinyl-CoA synthetase-type" evidence="1">
        <location>
            <begin position="31"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="205" mass="22372" checksum="DAB6BBFACD010F20" modified="2016-11-30" version="1">MWKNSIQTFSLSGRLFRQQKKEFLQSKRFLNLLEYQGKDILDKSGVAVQKFVVVDDASSISSKVNSFQVEEYVVKAQVHAGGRGKGHFNTGFKGGVHVLKDQKKVPDIVAAMLGNKLITKQTPASGVPVNSVMIAESVDIYEEKYLCFLLDRSSSGPICIASPAGGVDIEQVAESNPEKIKTVAIDVMEGLTPSAARRHCPIFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9U4</accession>
    <name>A0A1D2N9U4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Teneurin-a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_04658</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the tenascin family. Teneurin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000128">
        <property type="protein sequence ID" value="ODN02024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9U4"/>
    <dbReference type="STRING" id="48709.A0A1D2N9U4"/>
    <dbReference type="OMA" id="HEECEIT"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008045">
        <property type="term" value="P:motor neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008038">
        <property type="term" value="P:neuron recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000021">
        <property type="entry name" value="Teneurin transmembrane protein 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000013">
        <property type="entry name" value="Teneurin transmembrane protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057627">
        <property type="entry name" value="FN-plug_TEN1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056822">
        <property type="entry name" value="TEN_NHL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056820">
        <property type="entry name" value="TEN_TTR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051216">
        <property type="entry name" value="Teneurin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057629">
        <property type="entry name" value="Teneurin1-4_GBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219">
        <property type="entry name" value="TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219:SF69">
        <property type="entry name" value="TENEURIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25024">
        <property type="entry name" value="EGF_TEN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24329">
        <property type="entry name" value="FN-plug_TEN1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23093">
        <property type="entry name" value="GBD_Tenm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25021">
        <property type="entry name" value="TEN_NHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25020">
        <property type="entry name" value="TTR_TEN1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="Carboxypeptidase regulatory domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="258"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="421"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="484"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1221" mass="134562" checksum="10F0F71999BA0817" modified="2016-11-30" version="1">MGNCSRYPGTGCIVVEDAKVMARGDKHYPVIDLTSISPKTSEVEMVSPTSLVPEVTSKDFGGYNEGLSPMEILWGQVLTSRIQPYSYWTLELDMRDSAYANLNFSFPWGSNWALLFRKNALPSITQHDLMKIVKNGRIEHRNKIRHVRWALADSRPTFTTTNNNNSYPNLHNASTTRPNFINLHRVKRDSFADQSFLVFSEYLESGKWFLRLFNDDLLERKVSVLANIDANAEVRCPQQCTGNGNCVYGKCHCFDGFGGVDCSISVCPVLCSNHGRYSGGICHCEAGWKGAECDIPEAECEIGNCNGNGDCVAGKCVCRKGWTGAFCDKDALKATRGGGVKTAYLSLLFVIIGDCADPTCSEHGSCYDGKCLCNEGWSGILCNVPDTLLAKCIPDCSSRGEFDAASGRCLCQKPYVGPNCMEVACDKECGQNGFCNAEGKCECKPGWSGDHCEFLTCDSRCQEHGQCKNGTCICSLGWNGKHCTLAGCSNSCSHHGSCIMQDGWYSCKCSSGWAGEDCSIRLETNCSDDIDNDEDGMTDCSDSECCDDPNCRDHLMCMTANDPVEVLLRKQPPSVTSSFFQRVKFLIEENSVQSYAQKDEYSERRVSVIRGQVLSPDGLGIVGIRVSVDKSSRFGFTLTRKGGWFDMLVNGGGSVTLGFSRPPFRHLTRTVFVPWNEIVVLDPPVIMAATGAHARDGQVEEVKETSQPPCLQHDSEMLKPFVMSSWLPGMVGANPQNSLIFTETQILQQSIVIPGSDVHLLYHSSQSPGYLATVLMQLTGPEVPQDLSLVHLKITIEGELYRKTFEADPNITYTFGWKKRNVYQQKVYGVASARIAIGYQYSTCSRPIWTVQTVTLKGFDVDIADVGGWNLNIHHHYNFHEGILQKGDGSEVHLKELPRIVTTIMGEKGQQRSLLCEPCENKLLSPIALATGPDGSIYVGDFNLVRRITPDNVVYTVLQLSATKVSHQYYMTISPADGHLYISDPEKYQILRVNLMDQIEDPRVNYSPVVGSGLKCVPGDPANCGDGFPAKLAKLNHPKGIAITSDGSIYIADGPNIRYVDGHGIIRTLIGSHTHRGSRSGMIKTTDFESCRVKRKDMALVQLHWPSNLALNLVENKLLFIDEGILFQITDDNQLERVFGCDSSDKVVRPILDLAFSPKGQLYFVTEDSNLYTVKRQGEVLLVRTDKISPYGHNITSASLSAGVAVGERQRNNLDAGLCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NA92</accession>
    <name>A0A1D2NA92_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000122">
        <property type="protein sequence ID" value="ODN02173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NA92"/>
    <dbReference type="OMA" id="FMWELED"/>
    <dbReference type="OrthoDB" id="10520485at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="192" mass="22162" checksum="87B759463EE8377B" modified="2016-11-30" version="1">MCLSQWCRCGPSVAKPVHVISILDLISSVVFVTYEATNFGVLTGFIQPYSERNCSVNCTTTLKNYIPEYWTFNFETFTTMTLIVLVFLGFIIEGFLYSKLKTGRRDKIHLFCKKWFECRVALLLITVFMALAKALRGFYILEVDGVIDVITKFYRIVTLYIVKCFMWELEDTVGVVYTKPPRPRKRGSLALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAL2</accession>
    <name>A0A1D2NAL2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Citramalyl-CoA lyase, mitochondrial</fullName>
            <ecNumber evidence="4">2.3.3.9</ecNumber>
            <ecNumber evidence="18">3.1.2.30</ecNumber>
            <ecNumber evidence="19">4.1.3.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">(3S)-malyl-CoA thioesterase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23">Beta-methylmalate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Malate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">Ocin01_04372</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="27">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway. The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite. Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate. Also displays malyl-CoA thioesterase activity. Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. Also has very weak citramalate synthase activity in vitro.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(3S)-citramalyl-CoA = pyruvate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:22612"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58668"/>
            <dbReference type="EC" id="4.1.3.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>propanoyl-CoA + glyoxylate + H2O = 3-methylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47628"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:87810"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="4"/>
    <dbReference type="EC" id="3.1.2.30" evidence="18"/>
    <dbReference type="EC" id="4.1.3.25" evidence="19"/>
    <dbReference type="EMBL" id="LJIJ01000117">
        <property type="protein sequence ID" value="ODN02292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAL2"/>
    <dbReference type="STRING" id="48709.A0A1D2NAL2"/>
    <dbReference type="OMA" id="AWLFCPA"/>
    <dbReference type="OrthoDB" id="1773at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047777">
        <property type="term" value="F:(S)-citramalyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106064">
        <property type="term" value="P:regulation of cobalamin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000014">
        <property type="entry name" value="Citrate lyase subunit beta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040186">
        <property type="entry name" value="Citramalyl-CoA_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11105:SF0">
        <property type="entry name" value="CITRAMALYL-COA LYASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11105">
        <property type="entry name" value="CITRATE LYASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 27" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 25" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 25" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="26">
        <location>
            <begin position="70"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00055540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00061542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00066460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00072098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00076231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00076788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00083020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="ODN02292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="371" mass="41387" checksum="865038C67F69008C" modified="2016-11-30" version="1">MAHFRPLLCLPSNAFVSAGGRNITGGHVAEVFGGNSNKKQINVFSKLLQYSSYSTDNSPSEYTRKYIPRRAVMYVPASDLRKIAKIPTLGVDSIVLDCEDGVAVNKKEEARTHIRKYLDNYSKNSASRPELTVRVNSVQSGLCQQDLETILPARHLPSAIHVPKVDGVDHLKWFTETATKILGKERNIHQKINLIIFVESAMSLLSLPHICQTAWDLSTKSHFVPDAVVFGSDDYCADIGATRTNEGKELVYARQYIVSVAKAFKLQAIDIVYIDYKDIDGLRKQAIEGAQWGFTGKQIIHPNQVPICQEAFSPSLEKIEWARELIQGFEKHQKSGKGAFTFRGQMIDMPLVLQARNIVQLAEIVEKATAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAW4</accession>
    <name>A0A1D2NAW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Homeobox protein XHOX-7.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_04273</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Msh homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000113">
        <property type="protein sequence ID" value="ODN02393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAW4"/>
    <dbReference type="STRING" id="48709.A0A1D2NAW4"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048598">
        <property type="term" value="P:embryonic morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050674">
        <property type="entry name" value="Msh_Homeobox_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24338">
        <property type="entry name" value="HOMEOBOX PROTEIN MSX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24338:SF0">
        <property type="entry name" value="MUSCLE SEGMENTATION HOMEOBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="40"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="42"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN02393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="96" mass="10965" checksum="CDF50F7B81501088" modified="2016-11-30" version="1">MSIFNISNSAVIETRTKNPDDPSAPPKIPSPVKCTLRKHKPNRKPRTPFTTQQLVALEKKFREKQYLSIAERAEFSSSLNLTETQLYLTCFLLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBB1</accession>
    <name>A0A1D2NBB1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04143</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000107">
        <property type="protein sequence ID" value="ODN02539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBB1"/>
    <dbReference type="STRING" id="48709.A0A1D2NBB1"/>
    <dbReference type="OMA" id="FLANAPW"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="11">
        <location>
            <begin position="58"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="29907" checksum="62A5C1D9044D2085" modified="2016-11-30" version="1">MSLYVRKLSSYFVIKLGQLSAVHPKPKALSTSTRAEKSSKMNGNGNGSLGGRGALIVLEGCDKAGKSTQCRLLVEALKKAGKPCHLYAFPDRTTEIGKVIDEYLRCTKNLSDEAIHLLFSTNRWEVMPKIRELLLNGESVVLDRYAFSGVAFSAAKGTLDLAWCMGPDVGLPQPDLVCFLNLSKEAASKRGDFGRERYEKTEFQDKVKSIFLKIQDPAYWKIIDADRTKEEVQSELFQLSIAAVDTSENKPILKLWDSKSKKKEAEAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBT8</accession>
    <name>A0A1D2NBT8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial</fullName>
            <ecNumber evidence="5">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">E2K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_03960</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000098">
        <property type="protein sequence ID" value="ODN02701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBT8"/>
    <dbReference type="STRING" id="48709.A0A1D2NBT8"/>
    <dbReference type="OMA" id="SMWSEQV"/>
    <dbReference type="OrthoDB" id="5391403at2759"/>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000006">
        <property type="entry name" value="Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="17">
        <location>
            <begin position="83"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="152"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN02701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="449" mass="49193" checksum="7CA0266CB02A1516" modified="2016-11-30" version="1">MLKVTIGRSSRKYLGQCASLWNTRSGSSKFSQWAVTTRNGIATRVPRSAVNLIISELKVAHESPRWLAGARYFHVSCPMSSDVKIVVVPQFADSISEGDVRWEKAVGDSVNEDETVCEIETDKTSIPVPAPGAGIIEEQFVDDGATVLSSKMHQLRRHHHPTSSGNKAGPCSRCSPPPKPAAAAAGPPPTTTTTSPKTFRHQDKVPPADPTKEITGTRTEQRVKMNRMRLRIAQRLKDAQNVNAMLTTFNEIDMSNITEMRKTYGDAFLKKHGMKLGFMSPFVKASAYALTELPVVNAVIDDQDVVYRDYVDISVAVATPKGLVVPVLRNVEQMSYADIERGMAALAVKARDGKLAVEDMDGGTFTISNGGVFGSLMGTPIINPPQSAILGMHGIFDRPVARNGQVVIRPMMYVALTYDHRLVDGREAVMFLRKIKACVEDPRNLLLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBZ1</accession>
    <name>A0A1D2NBZ1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Endoribonuclease Dcr-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_03916</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBZ1"/>
    <dbReference type="STRING" id="48709.A0A1D2NBZ1"/>
    <dbReference type="OMA" id="DHTHRAM"/>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070578">
        <property type="term" value="C:RISC-loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004530">
        <property type="term" value="F:deoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031054">
        <property type="term" value="P:pre-miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000004">
        <property type="entry name" value="Endoribonuclease dicer-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044441">
        <property type="entry name" value="DICER_DSRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20932">
        <property type="entry name" value="Dicer_dsRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PAZ" evidence="14">
        <location>
            <begin position="158"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="13">
        <location>
            <begin position="423"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="13">
        <location>
            <begin position="669"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="326"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN02768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1110" mass="126740" checksum="CA027E04AF810A82" modified="2016-11-30" version="1">MCVAPEIIEKSSIIVANKPVSLYEIKIKIHKYSGDPRAETLYEFKERGHTFGVITNANLDDLPTFNLNANYGTFVVKVKKVKTTDSCIMLTEEEICLLEAFQQFLCDSLYEIKNPVLTTDGRHFLVAPIVGQSVNQAINWDLVRKCLELDEDRLLTKPDEDVLEGMKLTSQFENALLVPWYKNDQSLELLCSLSILDGSSALSDFDDLHKARTFQEYYSKKYNVQLRHPELPLVVCRSVGKQLNFLTKKVDGKVRRKEMQRSIMKVIPELANIHPVPASLYVQGRLLPSIFQRINRLLVANKMRQDVASYFNWDIGSGDNSVALIPFTNDSTSDDDSSSDAENSMELQQQSSSSEQTSPVKEKKKFFNLETINPFEITWDLLYQAEKPSPKRNSRDTKYCMPTPPTMKSDIRLKTIDEVRVQSYDFDQETDFDKEKGPSMNTIMEAITLSNAQDNVSLEKLEVMGDSVLKLLVSLHLFRNFPTWDEGKMTLLRTKLISNLHLYQLGKNKQIGELLSGSIFIPDKNWLPPGLAIPQIFSEYVVNEGLDYDIYTRLQKSTIEEMKSMNSTDKFKELIENVQGALKKNSEHTNYSHSKIGDKSVADCMEAIIGAYYMNGGIDGAMRIMEWLGLRAPLVDGSVVNYSRDTTLMPVEEERNSIRPRKQNLIPYLNDLERVIQYKFKNPWLAVEALTHPTFVGNRVTPCYERLEFVGDAILDFLVTNYILQNTPITDPGEITDLRAALVNNVTFGSLSVRYGFQTYLKYTSKPLGDYIYKFKEYQEENKHEVTDPHKLYSDFDCPTVKEIEVPKVLGDIFESIAGAVFMDSGMSIDTTWKVFYRLMEKELVKFSKNIPKSPLRELHEFYPGKVNFRKYESEANPKNNKSNSWSKFKIVYLQVPDCEKFIVGIGATVKQAKQAAAKYVTLNHENRSIEVTHIYNKNPFIMDSRFLLVAPLALTCLFVLSQIGQSLSQEEVEIHGYHFHTYFFQTNERNTQEALAFRAAIQNQIDGGFLENCRLNRVNMAPVGPHPIGSYETCCNKTSVSQALTWFMQNHGNLSILLHPLTRYEVLDHTHRAMFLGEKLPLDVSVLSEDLAENLDLCLPIEGNHINSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC05</accession>
    <name>A0A1D2NC05_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000095">
        <property type="protein sequence ID" value="ODN02788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC05"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="500" mass="55418" checksum="D2343D9CBD5758CC" modified="2016-11-30" version="1">MSDSETALAVAAAIAALRDDEDEEMTQVVSQSTMPPPAVPGSTAEEGEGSKAAEEPEQVVEKPKPKLKVMSCLICTTPITTENTQMGSSNPSEEYERMMRVACRLLCVDNHPLLKRWKFRHSEEPKKLCCDACCEVIFNLGSLQSIIDRTRLAINKKLDWILKTVSDSAAEESDEIEKVFFAGRSDIFRSEVLEVCKRKKNAKNGLADDSDEEEELVNSSTQTDVSGDSGVNDVRTKAGLKFFDERPERPERPSYSFDDASMDTYSDHNDDMSFSNTYDNDKDDTTTSFSTPKSEPPKRANAKKTPASTSSSSSSKQPSKRGRPSKRPAKYDEFSDDDIEILEEKKTNKPKGRGQPPAKSSRMDARELVKVEYNSDAMAGRPKRSTAAKRPNYQVLAGDDDDEYSSGYKRSSSGTDYLSKNKKPATGRKEVTLSAIPIVKDASGKTYFEGVEIVRTEKSITCKHLGCYYVVDGSGYNAFERIKAHIHETHIGEGALPDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC64</accession>
    <name>A0A1D2NC64_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Brefeldin A-inhibited guanine nucleotide-exchange protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_03850</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Perinuclear region</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
            <location evidence="3">trans-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NC64"/>
    <dbReference type="OMA" id="EVMCAYI"/>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000143">
        <property type="entry name" value="ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.20:FF:000002">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="12">
        <location>
            <begin position="769"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN02842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1899" mass="214154" checksum="2645F5272D717AA1" modified="2016-11-30" version="1">MVCGVLSTKEMFIIRALEKILSDREIKRSHHAQLKRACEAALEDIKSALQVIQATSPTSDQGIAGDNASAALPLPKSETSIPIDSEKYFVPFELACQSKTPRIVVTALDCLQKLIAYGHLTGNCSDSTTPNRKLIDRIVETICGCFIGPTTDEGVQLQIIKALLTVVTSQHVEIHEGTVLLTVRTCYNIYLASKNLINQTTARATLTQMLNVIFSRMENQHALSRHSVSDTSVGSASNFACKESGGQDECNGNEDSSEKDNETDPAAELTPTVDKDITSEEVDSEKDNIEPVVNNEVISESSEEVQVEKDDTNASSNNNNSDSASSKVLNGSGGHSEENADDNENKVDEAQEQEEKSKNAQDQEVLESALVNGDENHSSPSGDDEDRPNVEVVEKDASPKVHIPKYRFRNLPPMKLRRTCWKICWKKWMNRHSSQEKLIPRLHLLYLKILLPPSNFISSPNTPTITRVPSQESMDASADNDSASAHFVHILQKDAFLVFRALCKLSMKPLPEGVPDPKSHELRSKILSLQLLLSIVQNAGEVFKSNPVFITAIRQYLCVALSKNGVSSVPEVFQLTLAIFLALLANFKTHLKMQIEVFFKEILLPLVEAPGSSFEHKWLAVQALTRICGDAQCIVDLYVNYDCDLSAANIFERLVNDLSKIAQGRQGIDLVGSNAVQEKAMRVKGIEGLVAILQCMVEWSQSLYVSTNSQSNLGKKTPTLDSDFVNPLWNSEDQSMYCVIKGSERERNAIINDEELEVKKMESEYNPEQFEQIKQQKDIWEHGIELFNRKPKRGITFLHERKLLGETADEVAYFFHTDERLDKTIIGEFLGDPDKFHKQVMYAYVDQMDFKDKDFVTGLRLFLEGFRLPGEAQKIDRLMEKFASRYCECNPTNGVFASADTAYVLAYSIIMLTTDLHSPQVKHKMTKEQYIKMNRGINDSRDLPEEYLSQIYDEIAGNEIKMKGTSKLGKQSNLPNDKRRRLLWNMELEELAATAKSLMESVSHCQASFTSAKHLEHVKPMFKLAWTPFLAAFSVGLQDCDDPEISNLCLDGMRCAIHIACIFHMRLERDAYVQALARFTLLTASNCQLVEMKSKNINTIKTLITVAQTEGNYLGSAWLDILKCISQLELAQLAGSGHRTGKEVSKSALTWAALGGSSVENSNDPMSLNLNLLDPSVKESIGETSSQSVVVAVDRIFTGSTRLDGDAVVDFVKALCQVSTDELTNPHHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVLGEHFNRVGCSANEEVSFFAIDSLRQLSMKFIEKGEFANFRFQKDFLRPFEVIMKKNLSPSIRDMVVRCITQMVNSQSSKIRSGWKNIFSVFHLAAADIDANIVDMAFQTTNKIIGELYDKSLVTLVDSFQDAVKCLSEFACNAAFPDVSMEAIRLIRHCAKYVHEKPQLLVEHSMDEITVAEEDRIWVRGWFPILFELSCIVNRCKLDVRTRGLTVMFEVIKTYGENFQSHWWKDLFQILFRIFDNMKLPEQHQEKAEWMTTTCNHALFAIVDVFTQYYESLGPLLMDDIFTQLSWCVQQDHEQLARTGTHCFEHLVISSGSKFSPVAWNSTCNFIKTVFKSTQPQQLLSYKPTETNHVEEVLRRPSITSAAEAALNSPLPEQERIFSVLLIKCVVQLELITTVDNIVFFPATSKKEDAENLALAQADIDKLSGFDQQKEEQGMYTFLSNANLFLLLDCLSEAHRFATVFNLDNEQRNMLWKAGFKGQTKPNLIPQETQSLATSLRILFRMYLDESRAESFEEIEKRLILTCKGALEYFLLIPSNSHRDTWTNLLLLCLTKVLKLPEERFKTHTNHYYPYLCELVCIDLKAELKAVLRKYFMRIGPAFGICNAIPQCLTPSANSGNPSISSIGSSNGQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NDC8</accession>
    <name>A0A1D2NDC8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kibra</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000080">
        <property type="protein sequence ID" value="ODN03268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NDC8"/>
    <dbReference type="STRING" id="48709.A0A1D2NDC8"/>
    <dbReference type="OrthoDB" id="5919042at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="364" mass="38531" checksum="5DDDD7C97F274256" modified="2016-11-30" version="1">MSAPMLARGNQVFKSVERASEAAKLPGDSKTMTTLLEDERIQQLFQLPTAIDPHGPKGKEAQKMLKLLKKTSREIYKLRKSKTPRGQPDMISFKEKITFFTHNPVAMSAFAKDSDNVEREESASQQASSSTSVPYSSCDPNGSGTIILEEEEEEDEDEGEEEVSSSVEEPSTSSSSSTRPSFFPHPGQSSSIKSINPAGPSCINKFPSSSPTVKPRISKSAASYSSTSSQTNEASPSPCSSDSNKETESQCSVATHCSDNSNLVPSAVASVSSPASSTSCPVSSSRSHQNSGPAFAHPGGNHVDVNRDSSKLSKVVAGAASSSAPVAEPGSSSTESNVHTAKIDKKLPSKESNSNPHIEYVVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NE22</accession>
    <name>A0A1D2NE22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">E3 ubiquitin-protein ligase RNF13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_03184</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000071">
        <property type="protein sequence ID" value="ODN03499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NE22"/>
    <dbReference type="STRING" id="48709.A0A1D2NE22"/>
    <dbReference type="OMA" id="GFSCAIC"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000429">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF20">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="305"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="356"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="480"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="512" mass="57472" checksum="FDFA8FF0822B5307" modified="2016-11-30" version="1">MDTANQSQYCDRRLRRLLNQPLWFYVPILLILVTSSSATVYVVSEISNETVIAVNDMPARFIPERYAFYGMQGYLVYADPPTACTKVKPPPTPYAPSLDYPISWILLAKRSPDCHFQTKIENAQISGYSAIIIHNVGSNDTEVMGVEDPGKLMIYATFIGEYDGWMLKNYTFPSPFFLRIRNEFSVNSYLLPFAVIVGICIIVMLLFMVRLLWQQVVRWLRERRRSRRRKLPASALKKLPIHKWTKGDPYETCAVCLDDFVEQEKIRILPCYHGYHIQCIDHWLTKGRRVCPICKRKVIVADERFSDSDTETEDENAPLIPTTSTSQNPPSGASTFIQNHINVRVIGIGSRRLLTRNRQNPVNDSDASSISSGLSHSAADDQERGLTHSTTSTRPSTSAGRNSHSQSVFAEVHQSTEMLRKKLESQKQKKPDQSASSSGDCVQDSHEAGLDNSAYALECSSRDNDRDSNSVLDDAHNASVVPSEQLVVVVDECNSDGPAESNQDETDHSAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEK4</accession>
    <name>A0A1D2NEK4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEK4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905453" evidence="1">
        <location>
            <begin position="31"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="252" mass="28170" checksum="6C2BAFB48679AFDC" modified="2016-11-30" version="1">MSSLTLRRNFCVRVPSLLLVVFCILPENRTLHILSPSESGENPLEGLEWKWITEGCKIEVPGFDLIAYIGMGNQQTCMDSIRQNPNASIISEIPHCENQESYKGCWSTVMDALNTCVQTVKDVAGAIYFGLDSELLCDEAWITVVSNMRSNFEENPCQRDYSNINCEMDKLSSMDAKNLCLRFRSNSACDLDSVHNCTSQSDTGLYGEVYEKARHKLNCQSSIESNSGDIISGFLSMYIITMIIPTNIALKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEY5</accession>
    <name>A0A1D2NEY5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Alpha-mannosidase</fullName>
            <ecNumber evidence="10">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_02889</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LJIJ01000063">
        <property type="protein sequence ID" value="ODN03792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEY5"/>
    <dbReference type="STRING" id="48709.A0A1D2NEY5"/>
    <dbReference type="OMA" id="WIYQINR"/>
    <dbReference type="OrthoDB" id="2016903at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10810">
        <property type="entry name" value="GH38N_AMII_LAM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.50:FF:000002">
        <property type="entry name" value="Alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.50:FF:000003">
        <property type="entry name" value="Alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.30:FF:000003">
        <property type="entry name" value="Alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.110.10:FF:000001">
        <property type="entry name" value="Alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="entry name" value="Glycoside hydrolase family 38, central domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050843">
        <property type="entry name" value="Glycosyl_Hydrlase_38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607:SF3">
        <property type="entry name" value="LYSOSOMAL ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="Families 57/38 glycoside transferase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Glycoside hydrolase family 38 central" evidence="11">
        <location>
            <begin position="334"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN03792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1014" mass="115160" checksum="8043EBDAE53EB1C9" modified="2016-11-30" version="1" fragment="single">SCPKTKPGFINVHIVAHSHDDVGWLKTVDQYYYGDKNHIQWAGVQYTLDSVVEQLQKNPNRRFIYVESAFFWRWWRNQDEEMKETVRKLINNGQLEFIMGGWSGQDEGCTHYSGIIDQMSLGLRYLNDTFGQCAIPKIGWQIDSFGHSREQANLFAQMGFDGLFVGRIDYQYKSYLSRNRQMEMIWSGSPDSLGKPSWLFTGVLYNYYLPPDGFCFDITCDDEPINDDPNLADYNVDEKVEDFIRIAKAWAAPYRTNHTLMTMGSDFHYMAAHTWFKNLDKLIKYVNMRQVTHSSLVNVLYSSPSCYLQEVHKAKKVLNIKTDDFFPYSNDPHAYWSGYFTSRPTFKYYASQANKFLQVCKQLAVGTFNGKPPQSIIDEVWNLSEPVAIVQHHDAITGTARQHVTDDYSLRLGKGMESCEDVINKAFRKLQPAVSLVSSNVSVPNLTSPYRFCHLLNISSCAPTEEMKDFIVTIYNPLARDLHNEYVRMPVPTPGWDVYSQNGLIQTQIVPIPQSVQQIPGRSSTAFYELIFAIDILPGLTLTNFRIIQNLSSPTNQLNPVFTGGQANTSAASDGEYLFKNSKGVIVVLNKTTGFLKTVKQGSLELPVNQNFYYYLGMAGNNSKFAWRASGAYVLRPNTTKSAGDLPTPVTDRLLSYSIYEGVHVTEVHQVFTSWISQVIRLYDKSDLVEFEWLVGPVPVEDGYGKEVVTKYTTPMKTKGVFFTDSNGRHLIRRERNKRETYPFSKFEKVAENYYPVPSRMLISEKDYLALNGQTVVVLNDRSQGGTSMRDGEVELLIHRRLIYDDAFGVGEPLNEKAFGKGLVVRGKHWLLVCGEGTGIPISRNREVAQNIFMEKVVAFADAKVDNISNSQIAAHNNILLKPQSTMITALSKLLPPNVHLLTVEPITTSTFILRLEHFYEVHYDDMDNSSPVKISLKALKEAIPAIKSIKETSLGGNQWIEDVKRLEWITANEKRYGNAEGSFSSLDDSDSPLKSSEFIVLQPMQFKTFIVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF86</accession>
    <name>A0A1D2NF86_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DnaJ subfamily A member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02774</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000060">
        <property type="protein sequence ID" value="ODN03887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF86"/>
    <dbReference type="STRING" id="48709.A0A1D2NF86"/>
    <dbReference type="OMA" id="YGMEGMA"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="135"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="135"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="379"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="413" mass="45482" checksum="A5CE24D9D1D95E45" modified="2016-11-30" version="1">MAARGGVDSKLYETLGVTRGASESEIKRAYHKLAKEFHPDKNPAAGDRFKEISFAYDVLSDQKKRDIYDRYGLKGLQEGAGSREDLFGGFGGDIFSEFFGGSGMFFGGGGGHSRTRKGEDTLKALKVSLEDLYNGKSFKIKHTRNAVCGECIGSGTQSGKSAKPCQDCRGAGVKMQYRQLGPGLVQQIQTVCHKCSGQGNVIADKDKCKTCEGKKVAQDAKEIEVHVDKGMTHGMKITMSGEGDEEVATPGVQPGDLIFVIQQEAHSLFERQGDNLIMKHTLTLSESLCGFQFVIRHLDGRDLVITRTPGHVVPSDSIQIVENEGMPQYKRPFDKGHLLIRFKVEFPQNHFKDEQTLKLLETLLPARPEFVMPTGDNVEEVDLNDHHPTDYNATQESDDDDEPHGARVGCAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFC2</accession>
    <name>A0A1D2NFC2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aryl hydrocarbon receptor nuclear translocator-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000059">
        <property type="protein sequence ID" value="ODN03927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFC2"/>
    <dbReference type="STRING" id="48709.A0A1D2NFC2"/>
    <dbReference type="OMA" id="CVARPFR"/>
    <dbReference type="OrthoDB" id="7788762at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11391">
        <property type="entry name" value="bHLH_PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050933">
        <property type="entry name" value="Circadian_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001067">
        <property type="entry name" value="Nuc_translocat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23042">
        <property type="entry name" value="CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14598">
        <property type="entry name" value="PAS_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00785">
        <property type="entry name" value="NCTRNSLOCATR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="71"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN03927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="619" mass="68530" checksum="ADAC7351EA6352F7" modified="2016-11-30" version="1">MRRDKLNTYISELSTLVPIVAMATKRMDKTSVLRLSANFLRIHLSLKQNQKKETTNKYAPNGLEAQLSSVLLDSMEGFMLIVTSSGKIVYVSDTVEKLLGHSQLDLMGQSLYTVCHNGDVELLRHHLQPSKPFDPTKDNDPESAEAVMECVPRSPSFYGGRPEEAMSGLSSGERRSFYIRLAERTMARGDPTRHVTVHMIGVLRPPSKKDDKKANKKKDCSSTTAGDEHLLVCVARPFRNKGITELSLMEAIQDEYVTRHLPDGRIIYTDHRIAFVAGYLTEEVMGMSAFNFIHQDDLPWATVANRQMFSSVEGQGYSVYRLRSKTGTLIYLRTRGYLEFNKTTQKVESFVCINTLLTSEEGDKELEKERERITPFITFQQVTTTSTNASSSNVLPSTPSSESIVSKIVTTLTTTTVSRKEKPQSTCTKDPNSSILPRSSVVEIAELPSIEEPSNAMSLITSPKLLNPGVVEHHHVNGDSLVDSQDMSVADAVPTISSPQVSTISMIHDMLDGATVDQIIHIPVSTTLSNGPTSLLPANVVAISEPPVQQSTRRDIMPTRLKRSFSEIEELMVTTSAKRAIVPTAFITSYGPLHHSPQLGSKWGTETATMIFDQHNNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGA6</accession>
    <name>A0A1D2NGA6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 35 member G1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000048">
        <property type="protein sequence ID" value="ODN04298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGA6"/>
    <dbReference type="STRING" id="48709.A0A1D2NGA6"/>
    <dbReference type="OMA" id="HLLMTWS"/>
    <dbReference type="OrthoDB" id="6502282at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="78"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="239"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="394" mass="43744" checksum="BE90D4C6D7E546F5" modified="2016-11-30" version="1">MTILDTESGEYSAEESGEGVIMSSEHTPLLFPSLKPTLNYRDLHGVHYGTRENSKTVDGRKADGFGQTPVRKPCRKYLGILLAISASFLLSLTTLIARVLIEYHPFNEALWRFLGILLPSVPVLFWSSFSSKEPVFHTVYPLCDREKLKTLLVIFVRAFCGCTAVIFQFYALNYIEIGDVTVISFTTPVFVSILAYFFLGEKLGIVPVLIAFVTLIGIGIIARPPILSGTQEFDPLNLIGVALALGCMGFATFTYVALRWLKPVHYALVTFFYGLISVIECGICAISIGVFQFPLTLEHWLLAFGLGALAFAGQSLFTLALKFEDAGPVALIRTCEVIFTFLWQIMFLGQLPDAFSVIGAFLILLCVLLTTLRKLVMELPDESPMKARFQFLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGQ5</accession>
    <name>A0A1D2NGQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_02226</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000043">
        <property type="protein sequence ID" value="ODN04444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGQ5"/>
    <dbReference type="STRING" id="48709.A0A1D2NGQ5"/>
    <dbReference type="OMA" id="ENGHEQH"/>
    <dbReference type="OrthoDB" id="330772at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039853">
        <property type="entry name" value="Pinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707:SF0">
        <property type="entry name" value="PININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707">
        <property type="entry name" value="PINN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="10">
        <location>
            <begin position="107"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="355"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="126"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN04444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="410" mass="47900" checksum="147315F1CD421AE5" modified="2016-11-30" version="1">MLRNRANRNSQDYGDSHFAERTRRRRIDEYDDAEPMDKRQRLDGGNLANKNSPMVIGPRIRPRLSSEDEEYRSGGGGGGRRLQSRIVSSGKEKSREEVLAEQSKDKKGRDRNKRMFGALLGTLQRFKQEETKLKAKEEKRAQIEAKLDEAAKKERDEVRTKRTQLIRERKLRITEIKRLEIKRNRLSDLAAWESKTKYLANFIRTEAKPHIFYMPKKLNPIMECRLEQSKQYVTELIASKRKLVLEDLEDFEQRSKRYWERRLDGRETRRADPMDEDIEEELKEIMKTDDLTGDEDLAVDAEVEGEVEDFKVTVFTANDANEGNQIDEDNDVSETITITRQQSPDLEEEKDAIKIVLEPEDNGEIPTEKIIDEEDDAENGHEQHNDEENESPAQSENEEELEQTVENDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI17</accession>
    <name>A0A1D2NI17_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ankyrin repeat domain-containing protein 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_01757</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000033">
        <property type="protein sequence ID" value="ODN04920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NI17"/>
    <dbReference type="OMA" id="CKIMVPS"/>
    <dbReference type="OrthoDB" id="427518at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058018">
        <property type="entry name" value="AAA_lid_TANC1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058056">
        <property type="entry name" value="WH_TANC1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF10">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 29-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25520">
        <property type="entry name" value="AAA_lid_TANC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25521">
        <property type="entry name" value="WHD_TANC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="6">
        <location>
            <begin position="46"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="TANC1/2-like AAA+ ATPase lid" evidence="7">
        <location>
            <begin position="229"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="TANC1/2-like winged helix" evidence="8">
        <location>
            <begin position="313"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="553"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="586"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="619"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="652"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="685"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="723"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="756"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="789"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="822"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="855"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="888"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="921"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="954"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="987"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1020"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1053"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="489"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1137"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1424"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1144"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1195"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1227"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1239"/>
            <end position="1253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1444" mass="156913" checksum="F61F23EA448F77CA" modified="2016-11-30" version="1">MAHSLLEGKRFFCREWVFSKILHCLETLQRRVDEDGAGLNNGRNGILIVGGPGAGKTACCSEMVRPTAEHGKQLQLRKRLLAHHFCQSHDLNTLSLAEFIYQICVQLLESPLVEGYGEKVTEEDLSLKSIAEDPDAAFKKLIIFPLLEIECPQQACFLLVDSIDESYNSSQLPCNSSSCKGSFSNTISELLGNHCHLLPSWLILVCTARKQSKYIGKLFSGFRKIGLDDLRKSQVIRDVQQYILSRLDQDFALRQHIRRETAEMLNQLHIKSNGCFLYLEKVLDGISENFIVLREIREIPGTLYGLYLWLCQRLFTKKQFSKVQPVLCILLVSRQPMQESEILACLISRHPAITKEDFAKRMHVLRRVLIKSPDGYQFLFHHSFSEWFLDVKYCTQKYLCQQQDGHIMKAIWLASRASELNSCEVADLVYHLSHSTKLFGDLNQEVPLFLLSLGIKVLNEDFNLHAYDVKVVKLLAACGVTKQTVRTVPSKLEGSREPTRNGSDTCLDEGGGEAPCENSDDPAIRTCVTEETNEAESPAKVDVIGDVNQVDYNQRTPLHNAANDGNLAVVQFLISHNVSLEAVDRHGRTALNLAARQGHATVVRELLSAGVDVDHADNDGWTPLRSAAWAGHVDIVDILLAQTAQVDLTDGDGRTALRAAAWGGHEEVVNSLIKAGASPSLPDSEGRTPLIAAAYMGHADIVERLLSAGADVNHADSDGRTALSVAALCVAASQGHLKVVNLLLERSAEVDHQDRDGTTPLLVAAFEGHKEVCELLLEYEADVDAVDKAGRTPLWAAASMGHAAVCELLLFWGAYVDHIDGEGRTVLSVAAAQGNVSVVRLLLARGLDEGHRDNAGWTPLHYAAFEGHQEVTEVLVESGARLNETDNDGKHALLLSAQEGHITVLEALLNLGAVIDQRSHDGRTALRAAAIEGYRDIVQLLVSRGSDVNYRDADGRSTLYLLALENRVAMAQFLIRCGADVEARDVEGRTPLHVSAWQGHFEMVELLVSAGAEVNAVDNDRRTPLQSASWQGHSEIVRLLCERGSKIDHTCNQGATALCIAAQEGHLECVRALLEWGANPVHSDRCGRTPIRVAMKSGHVSISKLLEEIALARSKTMLAKGLNVADWDGLGTRHGGESLDPCKPSSSNFQPGFYPSSDNPACGTTESHFLPQGSTPDGEKRRSITSIVGGVGAPSNMTTSTKSSHNSNSEQSGSPGMLSRQDRSRRSTSGSNNNDSNSKQTGLSFTQQVQQLSRMKGRPGSRLLSPLNEPQSPIYASPPQSPSSDSINDDRMSPHSAFPRSDNAGRGSHNSGDFSGADIGGGKSGSPLLSNGCSVQPFAFTRDSHMKIILGNSSSENSGNGKNPRKNGLTYNANSSIISATSAIRSGLTALKAGVMEAAVGKKGQQDDSPLVSAASMAVPNLVRKKPVKSDGNGVVPWKRETPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIF4</accession>
    <name>A0A1D2NIF4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Xanthine dehydrogenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIF4"/>
    <dbReference type="STRING" id="48709.A0A1D2NIF4"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN04992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="64" mass="7096" checksum="B2F6701FBE05AE31" modified="2016-11-30" version="1" fragment="single">NYKLILPVDIPEDLRVTLLLKAPNPYGVLSSKAVGEPPFNLSVIFAIRNAIDSAKRDVGNNVWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIH5</accession>
    <name>A0A1D2NIH5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_01564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIH5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="237" mass="27397" checksum="8FF37BEFDCE4861A" modified="2016-11-30" version="1">MPGKKEPSEKEPFVPPVVKKYRVEVLNVSQSNAVVWVGNAGHSMETTLNGRAMGSKYWEIEFTDVPDIKIYGPSGKKSFGLRESHNMCNSFVIQDACIICKNQNPLQPRHTTANPEIYGTKQEQHIEILKNSSRKDSNYFIGDEWHNITGVLESGGILTWKLVISQVPQMITHQWCKIDELGSRRNKFSVVGSRKFVDGEEHEDIQIDYCDQQFEINDNWELLRNGVRQKLWKWDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK22</accession>
    <name>A0A1D2NK22_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein unc-13 D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01033</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Late endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the unc-13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000019">
        <property type="protein sequence ID" value="ODN05628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK22"/>
    <dbReference type="OMA" id="DINAPIC"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099503">
        <property type="term" value="C:secretory vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014770">
        <property type="entry name" value="Munc13_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052095">
        <property type="entry name" value="UNC-13_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45999:SF2">
        <property type="entry name" value="PROTEIN UNC-13 HOMOLOG 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45999">
        <property type="entry name" value="UNC-13-4A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51258">
        <property type="entry name" value="MHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD1" evidence="8">
        <location>
            <begin position="59"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="MHD2" evidence="9">
        <location>
            <begin position="291"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="418"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="593" mass="68161" checksum="22CED38E97F8D8EB" modified="2016-11-30" version="1">MRLLGVEYFDITYLVYDEKYCEIVKPIVAEICGSLKPLDLKNDDGCCQDKDVSMGTTLFELYLAVKQFSDLSSKVQGNTSDLCIHGTFHNWFHTTVAQWLDIAWFKAMNRIRRAVQLDTLKPLDDFNKITTSAVDTASIFHQIEIFWNQLSWPEVEGSYSFIAKILDDLCRCTIFYADLMCKKVEEMEKIADEKYHISDELCFAINNIERVAEEMQPISEKLGMNSIIEQLGEKNGPSVADQCRRTLITVMENANENINNKIIDILEKVGLKMRPVIQKLLLEGSETDSEEYGVEKLVKYLDKNLIKLNNKLTPATFDKVFAIIWENASVALRYLINTNIEVKRRPPSFFKQIHQMLQILINFFYPEGPAKVDLVYNSNIQEIEKLIGFYGASSTELILKYYQDRHKVQSQKTIKNSDLGSLTIRAHYCEDIRTLRVELLNARNLKPHDANGQCDPYVKVKLVPKEFFPSAPIFKTKIKKKTLFPLFDEIFSVPLSPDELSTGGIIMFTLKDHDLFGRNDFLGECFLPLESIPFTTSDTKLQDLPQKLLPMTLPKDPNSITLQTLESRQWDRSAAEFVKKERTKMIVSPNAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NK36</accession>
    <name>A0A1D2NK36_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Stress-induced-phosphoprotein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01077</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a co-chaperone for HSP90AA1. Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Dynein axonemal particle</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000020">
        <property type="protein sequence ID" value="ODN05597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NK36"/>
    <dbReference type="STRING" id="48709.A0A1D2NK36"/>
    <dbReference type="OMA" id="MYSAREN"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120293">
        <property type="term" value="C:dynein axonemal particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000004">
        <property type="entry name" value="Putative stress-induced-phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000010">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000002">
        <property type="entry name" value="Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000027">
        <property type="entry name" value="stress-induced-phosphoprotein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="5"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="9">
        <location>
            <begin position="137"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="233"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="308"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="368"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="402"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="436"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="9">
        <location>
            <begin position="497"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="199"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN05597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="548" mass="61533" checksum="307161FEDC39BEBD" modified="2016-11-30" version="1">MSDQANALKEKGNSALNEGKFWDAIKYYSQAIEVDPDNHVLFSNRSAAHAKAGNYADALKDGEKTVELKSDWGKGYSRKGAALAYLQRYDEAIACYETGISCDPNNAQLRQGLDEAKEAKNRQNAGPAPNFANPFSDPAILIKLKNDPRTSKWMDDPEYLALVRELQTNPKALGTKISDPRVMTTLSVLLGMEIADGPEEMDTEEAPPRPATPPPPKKETPPEPDIPEEKKAALKEKEAGNVAYKAKNFDKAIEQYKKALELDPTDMTYKLNSAAVYFEIKKYEDCVKECLDAIELGRENRADFKLIAKAFLRAGNSYKKMGDFRNAKVFYEKSLSEHRTPETRSLLADVEKLIKEQERKAYINPEKSEEEKEKGNELFKKGDYATAMKHYTEAIARNPEDARLYSNRAACYTKLAAFDLGLKDCDKCLELDPNFIKAWIRKGKILQGMQDAGKAMTAYQKALDMDPNNAEAAEGYQQCMSALHSNPEEMRKRAMADPEVQAILRDPAMRLILEQMQSDPKALQDHLKNPEIALKIQKLLDSGLIAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL51</accession>
    <name>A0A1D2NL51_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gustatory receptor for sugar taste 64f</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000012">
        <property type="protein sequence ID" value="ODN06008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL51"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="145" mass="16552" checksum="7D1695A99C987844" modified="2016-11-30" version="1" fragment="single">AVLTYRQVGALCDKINSMFSFHLLALYIASLTFYSHSLVQTLTSLKNVNGSSHWFLYLFFNFYFWNVACKVHSKALAASRGWIKQIQTCSTLGMEEKLDLILFSNEVETNSVGLHCKLFMLTYRLMTSMCGSILTYAVIVHQSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMU3</accession>
    <name>A0A1D2NMU3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcium-activated chloride channel regulator 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMU3"/>
    <dbReference type="STRING" id="48709.A0A1D2NMU3"/>
    <dbReference type="OMA" id="IRINHEY"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905760" evidence="3">
        <location>
            <begin position="27"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1018"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="933"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="933"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="980"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1046" mass="116343" checksum="08CF2E333FA0D2F9" modified="2016-11-30" version="1">MTFTQYFRKIGLVALAIICASPSLDAISLDENGYYDIVIAINEKTAQNANEKYLENLKNGVQDLSDALFESTTGNFSIRSADIVLPEHWQIDADAFATTQHYHNADIRINHEYQAPEVINPTLCGYPGRYIELPYNFFDLPDIGPYGLTGKALLTLWARYRWGVHDEHGYPDDPSFPYFWKKYRLPDQPETDPEDYQVTNCANTEVKGKFQNLNGEICEASEDGLSPPPSDCRFVPDEVNQTATSSLMSFHFINSLTRFCDKDTHNKRAPTRQNLYCRFLSVTEVMEQSMDFKAVKVNHTNIRTPIVYRIVKQVSKPLLYILSDSVFVPPETVINGVAAGLDTIFNDTQNWNVLASTAVYPSEARTDSYDTLYPLNFPWFERDKFVESFRSSFTIGRTGFRTFAAAIQDIGNAIKERRHKAGAIILVVKFGGDYDYFLPAYESEVLATILEQNIQVFALEGRDDYVMEPALQRLTQLSGGSHFSVGTGEDDETNVASIMSAIDATLKAGAVPPSRYRVAHKGTIMYNSDNTGTPIPISVLYGNVKKVSFFLSLLNTAFSSSFAITKGPDSVDQLPSFAETYIWGKSEFSITHHLAEIEQNFDEPTDWEYSYNCGGFECFSMMVVIVELEEAPASPLPGDEIEITISTSVEEDSISDLTVESAASLKGTEFGIYARLEKNGHPINSPDLEVTAHIHFFSDQGSFDGLYPKIVPLVDDGAGSPDFTANDGIFSGSILPISYPSGDQGAYQIFVVAKLRPKASPRSPLPIDQVSIKCGSGYLGCYSETVTEPFVKFADLRRRIVFKGTDSFYPGLLAASSRILDFRMKPHPSFQNGYNLIWTQPKVMTEYGAVRAEEYEIFYTEDFNKLFTTVTDLSKVVGLELPSVVGQERTHMVTIEPGLKYYYVIRAHGQANAPTPVLSNVLFIHAQNNYPDTTPRPTTTFTPAPTTPTTTLPPRSTVTTTLPSVTSTVPTSTDDEITTTRRTTTRTTPTTTSTTPSTTTLPVQTTTKQSKNWIKSTAAIAIFTTFGVVLVAMFAGGFIYYRIIHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMZ7</accession>
    <name>A0A1D2NMZ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar complex protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00089</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000002">
        <property type="protein sequence ID" value="ODN06589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMZ7"/>
    <dbReference type="STRING" id="48709.A0A1D2NMZ7"/>
    <dbReference type="OMA" id="GCLRYYL"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="756"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="768"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="790"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="815"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="831"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="849"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="865" mass="97939" checksum="1B9F0083021B1D96" modified="2016-11-30" version="1">MGKQRKDPRKEQELEIAEADVDEVGGGDVEIDEIDDFDHFLETLDDSSDSEGDDDEADPSQEDGLEVETSDDDDEDENMEPEEDEDLNEDEEESEENDEDEQESSDDQVNAEEGEEGAPLQNGIGGLGGASSESENDEEETGKKGMTAKKHKMDLQKLQETDPEFFNFLKQNDAELLDFNDSDDDGSDSDEEDALHKPPETLEEASDSEAEEERFDGTTEEHKSKVQKHLKKGIVDINVIAHWESQLSGTREISVLGDVIDALQCAVDSLVQGEESGGKWKVTGSANFNALIRLCVKEVKGFCVRFLCGNNNVAISEKNFDQKPFEVRDKSKQKWTRLRPKMKSYMEIIIQLFKCLGNPDAVASVLKHCLRMSGFWALFATKSYKMLRSLVNIWSQKEDACRVLAFLAIIRITNYSKDVFLLHMFKQMYISYVANCKFTSVNTWPAINFMRSSLVELYLLDTSLAYSVAFPFIRQLAIHLRNALSPNAVQSDGKLKKSEASRVVYSWQFVHSLHLWVDVLAQAGSNEDENLKLLIYPVVQICMGTIKLIPTKKFIPLRFHIVRMMIKLQDKTGSFIPVLPLITEVLRLTEFSNKGSKFSVRPIDLSVCLKADASESGYTKAVSENTFETILAYCKAIGTDLGFPEIVTPTVMYLKTFVKKQCKNIEVIKKFKALLEKIEANTKYINEKRNKALEDGTVTLADKKSHKILQVQMQTTKPHPPILAYAAEYFKVNQKVQIKSIKPALETREEKLIPKPTVLKQSKGKRANSKDNEFDKPMFESDSEEDDAEFATKLDDVAEAETEKKKKKKRKIPADEDNDDEDDVETQQPEKKKKKKKVKAKKAKKIELEASDDVQDELVDFELSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0G6</accession>
    <name>A0A1D2M0G6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ras-related protein Rab-36</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01009011">
        <property type="protein sequence ID" value="ODM59406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0G6"/>
    <dbReference type="OrthoDB" id="413584at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM59406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="193" mass="21936" checksum="F54AD5B2160B4D8B" modified="2016-11-30" version="1" fragment="single">GSKKQQITEFTPAYDESNNSLWLESIHAKLPDLFSDVNVDLEAYLNYIFLSVQKCYSQGQTVFVWGYGIPQVRNASNVLLLRTIEDRNIIVTVFDASNLESLSTCQRWMDDAVAPRSPRLKSHQLSLRMANLLQAEYWPISSKSGENVETIFPAHGLSWLLEIGLANETIVHPSQRDSINGQKRLCKLDHEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2K9</accession>
    <name>A0A1D2M2K9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_19482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005915">
        <property type="protein sequence ID" value="ODM87200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2K9"/>
    <dbReference type="OrthoDB" id="8195376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33198">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="14014" checksum="B1EC12DA3A248D68" modified="2016-11-30" version="1">MIPEATGSNKKDVNVRVAVTTVSLSCEDAVELYDTFTWENPNDKENFDLIYMPEAGESEPVDRYLTDLRKIADHCEFTDKPRRLRDQLVFGIRDDRVRERLLREPDPPLEKVIEKNQQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2S7</accession>
    <name>A0A1D2M2S7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E3 ubiquitin ligase complex SCF subunit sconC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005714">
        <property type="protein sequence ID" value="ODM87266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2S7"/>
    <dbReference type="STRING" id="48709.A0A1D2M2S7"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component dimerisation" evidence="2">
        <location>
            <begin position="72"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="125" mass="13887" checksum="23CADBB01E861E5D" modified="2016-11-30" version="1">MLDDLEQEGDDKVPIPIHAVNAETLDKHDAQGVEIAEFAPQVSAWDQSFLDVDQKTLFDLIIAANYLDIKGISALAARKVADTITGKTAEEMRAILGLENDLAPEEEDQIKKENAFLMTEKSFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M2X3</accession>
    <name>A0A1D2M2X3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose dehydrogenase [FAD, quinone]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_19389</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005657">
        <property type="protein sequence ID" value="ODM87294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M2X3"/>
    <dbReference type="STRING" id="48709.A0A1D2M2X3"/>
    <dbReference type="OMA" id="EHETKEY"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM87294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="363" mass="40135" checksum="2E30F6555D4DAFB6" modified="2016-11-30" version="1">MTVIIALNTILRVFPDRFPIPLPASAVIVVALTIAINSWVAFDRAKDFVTQNNIINLSTKHCQDQSFDYIIVGGGAAGMIVATRLANASRGATVLILEAGGDPSLLNELPSMDFFLLNQPANTWIYNTTPQAYACGACDDRKSLSTAGRMLGGSTSTNFMMYVRGNREDFNRWQYEDAGGDPQWSYKAVLPYFKKSEDYNGAHVNQSDSGVYHGRGGLLNVGTHDYMPGTDQFLAAAAEKGYRIGDYNGRDQEVFSSIDVTTQNGWRESTYRAFYRDTGKPENLCIRKYAHVTKINFASGNIGQNGYRPRAVGVTYTRHKKEYTVYARKEVILSAGTILSPKLLLLSGVGPAYDLQAMNVRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3S6</accession>
    <name>A0A1D2M3S6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bacillopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_19062</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004959">
        <property type="protein sequence ID" value="ODM87619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3S6"/>
    <dbReference type="STRING" id="48709.A0A1D2M3S6"/>
    <dbReference type="OrthoDB" id="7775224at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="45"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM87619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="140" mass="14722" checksum="A2437BBA3876D83B" modified="2016-11-30" version="1">MTRQIAHLIEPVDMKNVEALADEHQWGVVKIQAPEAWQELGTLSGEGVIIATVDTGVRGTHEALKDNFVGEYGWFDPSTSTPEPTDNNGHGTHTTGTIAGGKGIGVAPGAKWAACRGCASQLAGKAIFSHVETFSLAHSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4C8</accession>
    <name>A0A1D2M4C8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spectrin alpha chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_18846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004588">
        <property type="protein sequence ID" value="ODM87835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4C8"/>
    <dbReference type="STRING" id="48709.A0A1D2M4C8"/>
    <dbReference type="OMA" id="AMEHIRV"/>
    <dbReference type="OrthoDB" id="6018565at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000020">
        <property type="entry name" value="spectrin alpha chain, non-erythrocytic 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000032">
        <property type="entry name" value="Spectrin alpha chain, non-erythrocytic 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014837">
        <property type="entry name" value="EF-hand_Ca_insen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08726">
        <property type="entry name" value="EFhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01184">
        <property type="entry name" value="efhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="36"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM87835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="143" mass="16463" checksum="8BFF2CC4A3924806" modified="2016-11-30" version="1">MQEHFDKDKSGRLNQQEFKSCLRALGYDLPMVEEGQPDPEFEAILDSVDPNRDGHVSLQEYMAFMISKETENVQSSEEIENAFRAITSGERGYVTREELYSNLTKEMADYCVSRMKPYVDPKTGHPIPGALDYVDFTHQLFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4G2</accession>
    <name>A0A1D2M4G2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Neuromacin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004536">
        <property type="protein sequence ID" value="ODM87856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4G2"/>
    <dbReference type="OrthoDB" id="9988549at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038456">
        <property type="entry name" value="Macin_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM87856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="85" mass="9416" checksum="B9C62DE04AEEB79A" modified="2016-11-30" version="1">MLEFSKRRVKIAMKAWSLVRGWSSGATGVLWRDCAGRCRTCMGRESGQCVSGDFGCGATQQCQCSGGNVPRSTSWWDMQTCRWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4L9</accession>
    <name>A0A1D2M4L9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_18831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004550">
        <property type="protein sequence ID" value="ODM87851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4L9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903458" evidence="2">
        <location>
            <begin position="23"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM87851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="331" mass="36731" checksum="EF67F66A07FB43DA" modified="2016-11-30" version="1">MFNKMLPLLLFVLLIVLEQTQGQPVDDDNTPTKRWKTIGTQVFLSRWMAQDSKTATTLASSQPGIRSGGKQTNTQPTTTATTPFPYRETTSSTLRNDESSTALEFQDISPKFNTEDVSGFINIAATALLKNSGTTNSNSWLNNVEAEDTPPVVESSIVADIQEAFKNPQTFLSTVIKTATQVFSENQDTLQESRSIDVNVETTKQPATTIRTYQEEPNKLTATTTPFTVDLTAKIFEKLQTSVESILPLFKPERENEQTTTTKLGNSQGFDIEGILKMFNIDGSKASLIIDFISKNNINVLEVLRDSNVSLGEVLEIFRVEISAVRKLKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M4Z9</accession>
    <name>A0A1D2M4Z9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_18636</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004195">
        <property type="protein sequence ID" value="ODM88046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M4Z9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM88046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="72" mass="8096" checksum="48D32DCC87ABEBCE" modified="2016-11-30" version="1">MAIPTGKLVVESNDPRINYNLLPGETLLTCPYNYYHAVLPIKFNKHVLKLQPTSLQGSGQRWTGTVVWNLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6R0</accession>
    <name>A0A1D2M6R0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase CHIP</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">RING-type E3 ubiquitin transferase CHIP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_18027</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01003338">
        <property type="protein sequence ID" value="ODM88655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6R0"/>
    <dbReference type="STRING" id="48709.A0A1D2M6R0"/>
    <dbReference type="OMA" id="KDIAHRQ"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045862">
        <property type="term" value="P:positive regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16654">
        <property type="entry name" value="RING-Ubox_CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045202">
        <property type="entry name" value="CHIP_RING-Ubox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041312">
        <property type="entry name" value="CHIP_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18391">
        <property type="entry name" value="CHIP_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="9">
        <location>
            <begin position="229"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM88655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="305" mass="34651" checksum="DBA76CD81FC95A46" modified="2016-11-30" version="1">MASSQGAPSRGCKRSFSEMTAFDLIEEGHRHRSASNFVESMRYYSGAISKNLKIPTFFTYRAAAAFMLNRFDEAATDSRRALELQPEMVYGHFLLGRALCSMNKFDEGLCHIQQAIELGKQEGGYYDQNMIDVLIDWQKQRLEIFAVNETAKEQDLKSFLSRLIQDDKKAEICKINSPTCSRFVVKEDGETFETEVAKAQQRVEERAEANMTELHDLFMKLDISRANREAPDYFCGKITLDVLRNPVITPSGITYERETIEEHLSRNGPTDPMTGEPVTVAQLIPNLALQEAVNDFVQNNPWALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M770</accession>
    <name>A0A1D2M770_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003138">
        <property type="protein sequence ID" value="ODM88830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M770"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903549" evidence="1">
        <location>
            <begin position="20"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="73" mass="8150" checksum="7CDE2A2F6FF93E43" modified="2016-11-30" version="1">MNYLLCMALTLTLTTQLNAVPVRIKYDVSGAVWNEMISSTGNDGKVNMYSDWRAATVKLQQLDVSPDRAVRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M843</accession>
    <name>A0A1D2M843_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Orexin receptor type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_17525</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002852">
        <property type="protein sequence ID" value="ODM89157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M843"/>
    <dbReference type="STRING" id="48709.A0A1D2M843"/>
    <dbReference type="OMA" id="WAFLEST"/>
    <dbReference type="OrthoDB" id="10036964at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243:SF233">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="65"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM89157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="180" mass="19984" checksum="F2BEFB5F2619743E" modified="2016-11-30" version="1">MELLEGCNQSDFLINGTPFTAESKIPETGDDELLTKFIDDAALPLYLRITCLILFVVIFTVGTVGNIMVTLVISCSRDMRTSTNIFLVNLSIADLLVLVVCTPTALIEVTYHPDRWVLGFYMCKFVPLLETTVANTSVLTILAISFERYYAICRPLKANYICTKSRAAMICLAAWVLPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8E9</accession>
    <name>A0A1D2M8E9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit DAD1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_17414</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002760">
        <property type="protein sequence ID" value="ODM89267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8E9"/>
    <dbReference type="STRING" id="48709.A0A1D2M8E9"/>
    <dbReference type="OMA" id="HIILHIV"/>
    <dbReference type="OrthoDB" id="445566at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005588">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM89267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="112" mass="12351" checksum="FFBFFF29FF88D355" modified="2016-11-30" version="1">MTSVVGVVKNLLGAYEAQTPKKLKVIDAYLAYVLLTGIVQFVYCCLVGTFPFNSFLSGFISSVGCFILAVCLRIQVNPENKSLFLEISQERAFADFVIAHLLLHLVVMNFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8U1</accession>
    <name>A0A1D2M8U1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coatomer subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_17333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002707">
        <property type="protein sequence ID" value="ODM89352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8U1"/>
    <dbReference type="STRING" id="48709.A0A1D2M8U1"/>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="2">
        <location>
            <begin position="220"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM89352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="296" mass="33037" checksum="3BFA535585984D16" modified="2016-11-30" version="1">MIQWMDADPTGGWGDEDLPAERHSQGDGEATLAAGGGWDMEDDIELSPDLQVSGTVEVVFEQSLKGISVPQRWTNSSKYAIDHVYAGSFESTARLLYDQIGVVSIEPFRQLFLAAYLKSRASFTALPNLPALPFYPMRNTKEAAPAVGNPLSDLVQKLQGCFQLTTKGDFPEAVDKFQSLLLSIPLTFVENKSDLTFIQELVILCREYILGLQMELYRLKKNPVDEHAMEYDEQNPFSVCAVTYKPIYRGKPEVKCPFCRATFMPQFEGSLCVVCTVAEVGKEDVLGLRISPIQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M8V4</accession>
    <name>A0A1D2M8V4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002663">
        <property type="protein sequence ID" value="ODM89408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M8V4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="83" mass="9478" checksum="93ADFFFF1D2C1383" modified="2016-11-30" version="1" fragment="single">KRHPVPPPAQGEECHCRVELTFDEQQYLNISSCTKVVQNVDPAEINVSSCDGTYQFVVDYKPSRKVVRKAQEKYESETTDSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M959</accession>
    <name>A0A1D2M959_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ectonucleotide pyrophosphatase/phosphodiesterase family member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002616">
        <property type="protein sequence ID" value="ODM89479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M959"/>
    <dbReference type="STRING" id="48709.A0A1D2M959"/>
    <dbReference type="OMA" id="LEANEGW"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903652" evidence="1">
        <location>
            <begin position="19"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM89479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="426" mass="48335" checksum="FF70AF04979D9678" modified="2016-11-30" version="1">MHIARIFLAALLVHISVSVPLKNISDHPVVLVVSFDGFRYDYLNKVHTPTLNELKKRGVSVPYMEPVFPTKTFPNHQSIATGLYAESHGVVGNTFFDLKYNRTLNVNDSEFWNYSPDVLPIWILNEIAGGGRTSGCLMWPGSNQPYGFKNDSLPTYYYPTYNASVPWEDRVDIVISWITDKTKPANLVFLYFEEPDTHGHAFGPNHQETLNEISNTDNRTAYLIRKLKEVGIFDKINLILLSDHGMEAVTQDKIINITALIDTSLLKARYGSTPVVQLIANEGKGEELFTALSNHSKNYGFKILTKEEARYRFHYGQSRRILDYVLIADSGYAFDDFNLLLAKYNKKLNLTDDPAREYGVHGYSPEAQTMRGFFIAHGPAFRKGFVHQPIRNIDIVPLIGKLLKFPSVPSNGSLEWVVDMLKFSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC90</accession>
    <name>A0A1D2MC90_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_16174</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01001929">
        <property type="protein sequence ID" value="ODM90504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC90"/>
    <dbReference type="STRING" id="48709.A0A1D2MC90"/>
    <dbReference type="OMA" id="FPGRCAN"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000032">
        <property type="entry name" value="Phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="17">
        <location>
            <begin position="294"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM90504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="579" mass="65086" checksum="F7E3237BBB94075F" modified="2016-11-30" version="1">MPTVNVARDLLFERLNRKYTEEEFDHLCFQFGVELDEVSADEKDPTITIYKIDIPANRYDLLCVEGISRALSIFLGDIKPPLYKAVKPAAVIQTIVKPSTQSVRPFIVTGILRGVRVTKNIYNSIIDLQEKLHHNICRKRTFVAIGVHDLSKLTPPFTYSADPPTAIKFKPLNQTKEFRADELMEFYQADNHLKHYLHIIKDFPIYPIIRDSTGVVLSMPPIINGDRTKVDLEGKEEKTMDLFFEATATDITKANIVMDTLITMLSEHSSTKFEAEATEVVYEHSGETVLLPGLSTRSQEIDVKETNSVVGIQLKAEEMSTSLTRMGLKSTVKNKGTISVEVPPTRHDVIHVCDIVEDVAIAYGYDNIVAELPRTPTVAKQFPLNKITDLLRENVAQSGFTEALTFSLCSVEDECEKIRQKRAEVEKKLAKISNPKTLEFQTCRRTLIPGLLKTIQANKKMPLPLKLFEISDVVIIDEKEEVGARNERHLAAVFYNKNPGFETIHGLLDRIMALLEVGEKDYGLEACDGNPTYFEGRGAEIKVKGKVIGTLGVLHPEVCEKFELVNPCSALEINLEQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCG6</accession>
    <name>A0A1D2MCG6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Decapping nuclease</fullName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_16016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01001858">
        <property type="protein sequence ID" value="ODM90670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCG6"/>
    <dbReference type="STRING" id="48709.A0A1D2MCG6"/>
    <dbReference type="OMA" id="ACTPYEN"/>
    <dbReference type="OrthoDB" id="5853397at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="3">
        <location>
            <begin position="42"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM90670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="386" mass="45107" checksum="F2070DC089966AE2" modified="2016-11-30" version="1">MELEKEREIREPRKRTHAIAFDKFNITMERISENTPFPSFSKPWVAGCFSLDGDRKYLEGPQFLKFCHMPTTPAVKYDLNKQAALIRSLYTDSNEEESRRQTSELLHLLFWARKHKERFKRWRPHFVFYRGLMTKLLGTPYENQDGWKIAAMMRTKTIYLRELDTPESAASRQKFNSKPFLRKTAEWGRAFEYFLLSDEPESQPDPNGVKKEECNIVFRTKLGSHDLLYAAEVDGIIVKDGNEGNPKKQPELIQSSELVEIKTTRQFPSSEMPHKFRRFNLRKWWCQCFTAGISQVVVGFRDDDGMVEEVKSYPVDQLPKMGADWSSTVCFNFLDQFLSEIKRIIADDVTSVFILEFRPQKHSLQGVLQISVTVEKDSDKYLPSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDM4</accession>
    <name>A0A1D2MDM4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001690">
        <property type="protein sequence ID" value="ODM91049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDM4"/>
    <dbReference type="OrthoDB" id="8257766at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="139" mass="15638" checksum="84F28A77010437FC" modified="2016-11-30" version="1" fragment="single">MTRGFEPGRVSMNRLRQPSPGVIDFIRIRNGVEVETSRHTITLTDNQSFIFFTNCNLQTNRRSWDIMSTQPQLSAAVRRRIEQHATAQGFARENFAFMRYDSCRPGVVSGQGGQQEGNRNQRGSSSGGSNISGGRWNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MDS3</accession>
    <name>A0A1D2MDS3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uracil-DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001662">
        <property type="protein sequence ID" value="ODM91125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MDS3"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="451" mass="52178" checksum="5FF0EA7587F1F34B" modified="2016-11-30" version="1">MAEAFFKKIRDIGRDNYEKKFPKFTTLFKVLFDIQKGTHEYENVITWLNAAADDAYGFAPKEYFSNKINKSEIKNGIAAQLHTFLKENGFTEEILKTNIYSFWKALHWMCCQLQEYTRDENIFAFMTAQKISDVRVAIVGQDPASDYDFTKESKRSTGFAFHGVECPSTKNIIQFSIDEMNAIPHYVTIQDITKQMEKVTFLPDTSSKYLTEAKEDGNPKTPHGTPTSSNTWKPRNVLPKLANPTSDLGGWINQNVLLMNSMLTCKEICQQSSYWKYITDFFLDHIRAINKEHLWFSVFTWAHEYPKAVKQKKPEVDKGQQAEIKGKQAADKKDKGVKGNTGKNAKDKKGKNVKDRKDNNADDEVVTSYYADNEKKHLCIKVCHPSLTKERCRAMKCRLGRGKSWPVVQPFTKANRHFYDNQVWDHIVDWSARLTESVPDMNRKEDIIMFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFG2</accession>
    <name>A0A1D2MFG2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal peptide, CUB and EGF-like domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14962</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001445">
        <property type="protein sequence ID" value="ODM91726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFG2"/>
    <dbReference type="OrthoDB" id="8298994at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="3">
        <location>
            <begin position="16"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM91726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="129" mass="14289" checksum="F15B653584F99A05" modified="2016-11-30" version="1" fragment="single">AAYPPVNNKTGLLRKCGEVLGGSTGSINYKTDMSFEPNDRCIWVIVPQPGPRSKIMIQVSSIGIYDSDDHLYMMQLVDANGEELPNAPNKTKLVRYQIYEARSREVYIVFYSDSSSQGSGFSLTWSVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MFI5</accession>
    <name>A0A1D2MFI5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cadherin-23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001431">
        <property type="protein sequence ID" value="ODM91750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MFI5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM91750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="286" mass="32011" checksum="0AC39C3B53E6D4D4" modified="2016-11-30" version="1">MVHTFGISKLPTPMPNATTDIFCSDIGHFTLPKNNCIQVSNRVVSSEFVFAGQFCDSACLAEIEGAKSYAAQLHDNTNQDIDQLILRMTNLETRQKTYDAILERVVNLEYDLVNNITKLEKRISDDVAYVFTEIDAVRARVSTLESNEIADDFAFGDLSFQVSNLEKNLKGNTTQLSNQISNEIIGLNTVLSDYIASVNRDLNSRIDKVQASIPSTSPGNPTPFPPTTQVGSAMDVYYNLTRRIDNLEFGKISNLSADNNIWRQNFRVVNATFEKLKKNNYFPTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGJ0</accession>
    <name>A0A1D2MGJ0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heterochromatin protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14682</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001358">
        <property type="protein sequence ID" value="ODM92002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGJ0"/>
    <dbReference type="STRING" id="48709.A0A1D2MGJ0"/>
    <dbReference type="OrthoDB" id="1918685at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00034">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="106"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="169" mass="18779" checksum="A274F77281771999" modified="2016-11-30" version="1">MDSISSLSLGSEEYTVEEILKKRIGADGKPEYFLKWEGYGHDETLGTSGKYQCRALTSHAKIPSTEPSSNQRKKPSGRADEVKSRDYREKNESDDKPNVSGFDRGLEADEIIGANNENGGINVLVKWKGENGVEMVPSSVARFKCPDVLIKFYEENFTFAMSSSQNGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGQ6</accession>
    <name>A0A1D2MGQ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NACHT and WD repeat domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_14629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001341">
        <property type="protein sequence ID" value="ODM92054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGQ6"/>
    <dbReference type="STRING" id="48709.A0A1D2MGQ6"/>
    <dbReference type="OMA" id="HTANERN"/>
    <dbReference type="OrthoDB" id="2325716at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052752">
        <property type="entry name" value="NACHT-WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057588">
        <property type="entry name" value="NWD1/2-like_WH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871">
        <property type="entry name" value="BETA TRANSDUCIN-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871:SF14">
        <property type="entry name" value="DUF4062 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25469">
        <property type="entry name" value="WHD_NWD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NWD1/2-like winged helix-turn-helix" evidence="3">
        <location>
            <begin position="473"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM92054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="610" mass="70086" checksum="736E1618EB517026" modified="2016-11-30" version="1" fragment="single">VVDMRWGVRDEATDDHMTTELCMREIVNCQRLSMGPNFVVFLGQKYGYRPIPTYILATELTLLKETLQQMGVDTHLLDLWYKVDKNAVPAMMILQPISTILVNFNNKRYQTERYACSQIAKSRPGNLWDTLNKMQKLLRKAAHMCNVNGKMDHDAMHNYFMSVTEREVINGVLNVQNTKTSCIAYKASNFIDIINRGIDAEAARLLGNLRDERLPNKIEASNMQKYTIEWMGREGISKDTHDEYLSNFLAHFYKSITKLVDRAMRKEDSSAQGVIVTEILQHLHACNNSVKQCSCPMLISLCQQISYNFMLPMEDIPDDLVPLTAHFKQLITYGTAEQPLIVFLDSVDQLTGASGANKLTWLPSKIPKHCKIVISCVNEPEEPEISRDYVLLRRILDAEDHFIEVTSLGEKLATQVMRKWLIAACRDVTNYQWRVVCNALAECSLPIFVKLVFAETCRWKSYSKPNDTLLATNVMDSIFKLFERIEMQHGKLLVMHALAYVTAAKSGLSETELEDLISMDDKVLDDVYQYHLPPVRRIPPLLWTRIRNDLPNYLSEREADGVSVLSWYHRQFRDAAKERYFKDEAMSIYFHSSIADYFLGIWGGGNPKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGZ4</accession>
    <name>A0A1D2MGZ4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">Ocin01_14504</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="LJIJ01001303">
        <property type="protein sequence ID" value="ODM92181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGZ4"/>
    <dbReference type="STRING" id="48709.A0A1D2MGZ4"/>
    <dbReference type="OMA" id="CFEQDTC"/>
    <dbReference type="OrthoDB" id="306218at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051827">
        <property type="entry name" value="Cas4_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36531">
        <property type="entry name" value="CRISPR-ASSOCIATED EXONUCLEASE CAS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36531:SF6">
        <property type="entry name" value="DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 20" id="KW-0347">Helicase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="18">
        <location>
            <begin position="9"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="19">
        <location>
            <begin position="432"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ODM92181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="578" mass="65662" checksum="1361572F0DB639B8" modified="2016-11-30" version="1">MTDRLDSLTDLKKEAKTICTRPQMLERAYGIGLTDDELEKLQTSVAEWVARFMRVRFFGPADGKHNNFNFMDVLGVEDNIWTPTFGLKGKIDATVLIKKDGQLMTTPLEFKTGSTKSQKRQPIKSDHVGQVSLYTLMMSTKYGPIQEALLYYISDDSMSIHPPRNLELQQLLMNRNKLVRSTTLSEGDLPYLPRPDGIDYEFKCKTCEVRNICTLQIRKNKRPENELMNTEKALLANCNLSDEEFDFFEQWMKVINAETEEVEKRYNDKNLWTLDPEVREGSGTCIANLKLVGDSVPWEDSCGKAGFLASFEKKGSSSQFLANLKVNDFIALSSNVEVCINYGVIVSLRDNEITLFLDQTLHKEYKSGNFTYSVDKINTTSPIASQYGYLMKLMNDTPEAERLRQYIIMKKQPNFKKLLLPDPQLQQIVNDLNTEQSRLNWKSQSTDSFLFVKGTPGSGKTASIVRLLKALVYAKKSVLVVSYTGMALEHILKKFKEDNDEFIKINSSSAAEDSLRSHTTKELSNSVTSIAELTELYNKPVVGTTLLSLKHPIFQVRRFDYCIVDEASQALPTAVFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MH59</accession>
    <name>A0A1D2MH59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001284">
        <property type="protein sequence ID" value="ODM92251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MH59"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="636" mass="71339" checksum="F43E0514E10BC3F6" modified="2016-11-30" version="1">MSEVKGGTKKTVAMAESQEASPDPGRDCTDPMLNSVVLQTLFKYGSIEEIKTYRQVCRIWNEESLPRIRSRGWVKLVSSKFETDGLYFEDYLDGVNGADAVSDPFQFRKHPYNNFKLSNFKISLVDGDYGRQLEFWSKCGPKMKQLKISNSCFRSVEDFHAALFRFVPNLKSLKLKDTTVAWSEPGEDDENTIDLKDAPPESTVNSLQVLDIKTVGILPSWNWFFRRYPKIKSFTVSNLLTNMPGFVMAPLTVSKGYELEEILKIMAILARDCGISWELEKLDVLFMCGAHFENRHCELFGHLKLPLSTLCLHIGHFASAPAFKFLLETCANTLRKLVAYREDDRDHEIRQGFPFGVQLDALSELCLTGRGLRPNLDFLPFTPNLKSLILAQDIGSSLIAASSHVSGHETLGVISCRKMESGGRGSRGAKTVIGNTDFPGLEHLVCSNLEELIISGRDEKVCSSGHVAALCRLMPNLKKLMLGLGNDGFRVTCEGWKQLEVLVVQPFEVDQIGLTGNDPLQQQRLPNLSDLTGLRYFGMGVEIFGRPNTHLSNESVLNAIFPLKNLEAITAGYEADVDKMSVEIRDQLLSKFPKFIWKSSVRVYEWSGFRASGDTDESSEDDSDDWSDVEENSNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHC8</accession>
    <name>A0A1D2MHC8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hemocyanin subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_14329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001254">
        <property type="protein sequence ID" value="ODM92353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHC8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="83" mass="9176" checksum="4E9676AC5264DD4A" modified="2016-11-30" version="1">MDEDIIHLDDPNFSRNIIIPEMLGIYNRLVKGIKTGKLVGQNGQKVSIWNAFGMDPLANTVEATSISVNPCIMTLLESIIMDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MHT9</accession>
    <name>A0A1D2MHT9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_14288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001243">
        <property type="protein sequence ID" value="ODM92394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MHT9"/>
    <dbReference type="STRING" id="48709.A0A1D2MHT9"/>
    <dbReference type="OrthoDB" id="6428908at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF18">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM92394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="504" mass="56333" checksum="E8B98AECEB2346E2" modified="2016-11-30" version="1">MMSILDDDTLRLSLAIDDDSHLGGLSPPSLHLIEPKVYLRVSGESGMIRPANKDNEVLSSRTSSQKVEPRARELHEDDHEIEEDEETEDDDMNDNYHHHYPYIESYREKYTKPDLHHPFATSPTEDDSSSSIEAPASTKPKQVWSEIIAQVTTPSSFNEINSSASEHRLADFHFRANLPSYFYNKYSSYSEEDLENVADFDDDHSKYFVKTKPRSVTASGSNIYSNFYYEPPSFSTKSVPIPVKTDRKQFVFASAKPPTNNHDEEGSQHLYVDDHEEDAISHSHNHEDDHELPQQDATIMTTTLPNFTTPQKPYDAEGSSSKIQVDQNNASNRPLDATTSQSILSKVIINNDPDSGTTPQYEEKSETTTTTTFLSGTSTTTEATTTTTDATSIPGVPGIDYPILDEIPQTGFDCKNQRYKGFFADIDTKCQAWHYCDFTDGHSTFLCPNGTLFSKSSSLVIGGSTLIVIRQGSYTSSMRGCIGISNHQSRAFRRISLGSMWTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK05</accession>
    <name>A0A1D2MK05_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Gonadotropin-releasing hormone II receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_13421</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001035">
        <property type="protein sequence ID" value="ODM93261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK05"/>
    <dbReference type="STRING" id="48709.A0A1D2MK05"/>
    <dbReference type="OMA" id="KMNASSC"/>
    <dbReference type="OrthoDB" id="6435638at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097003">
        <property type="term" value="F:adipokinetic hormone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032870">
        <property type="term" value="P:cellular response to hormone stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241:SF59">
        <property type="entry name" value="ADIPOKINETIC HORMONE RECEPTOR, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241">
        <property type="entry name" value="NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 8 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="119"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM93261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="349" mass="40907" checksum="789F5F75E51375A0" modified="2016-11-30" version="1">MSLKEETLPQFYVSFSVETLSLLPHKRGFTIENSREYFKLPQMTPNSSIFFNNISSKGMLDLEISMSENYTEIFFEFWNNLSIFENSSERRLPIDMRFNNGHLLSVILYPILMTLSAIGNIAVFSVILRLRLKGKLNRIHLLVLHLTIADLLVTFLMMPLEIGWNYTVSWDAGDGLCRIMSFFRIFGLYLSSFLLMCISIDRYYAVIKPLAIYEANRRAKWMLAFAWIGSIIFSLPQALIFHVEVHPEFRWYQQCITFNSFPSRNVELAYNLISFFFLYVLPMLTIIFCYARILAELYRVNSQKQNDDMLRRSNLGVLGRAKVRMLKMTVIIVATFVFCWTPYNVMSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MKG4</accession>
    <name>A0A1D2MKG4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fatty acid amide hydrolase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_13209</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000976">
        <property type="protein sequence ID" value="ODM93473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MKG4"/>
    <dbReference type="STRING" id="48709.A0A1D2MKG4"/>
    <dbReference type="OMA" id="EPWRPEM"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017064">
        <property type="term" value="F:fatty acid amide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052096">
        <property type="entry name" value="Endocannabinoid_amidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45847">
        <property type="entry name" value="FATTY ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45847:SF6">
        <property type="entry name" value="FATTY ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="4">
        <location>
            <begin position="233"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM93473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="718" mass="79049" checksum="561A30C555A25816" modified="2016-11-30" version="1">MSGGLKMLSGSDMSPSKDNLIISSLEDVHITSDEVNMDISVEISSKNGGGPDNKESHQKPNKDKVGIQSSPHLDDVTVTQQKNLINNGSLRNKEQQQQQKKKQQQYNPFLVAQPPSLTMSKGRDEKVQLDREEHNSVIGHEVIDGNNGTATTEGPMVVEVDPVMDELDRRSCCESERSRLDRIMRKKQDERSAEFSRMQSKFRLEGDNKLILNLGWEELVQALQKRELTATAVLEAYKAKALDATLKYNNITDFIPQATQWAKELDSLPEPKGPLHGIPFCVKDDTNVEGLDTTLGYAKRLYQPATETAVLVRTMMDLGAIPFCKTNVPQTLFTYGSDNPVFGCTVNATNPKLSPGGSSSGTGSLVGAHGCMFGTGTDIGGSLRIPAHFNGVASIKPTVGRLSNMGIVSSLPNLVGLTAVPGVIGKTPSVVTTVFKGISENLRQHKYDPQVPPVPWADEIFKSKEKLRIGYFYSLPYFPAMGDTQEVVQRAVSSLESLGHTLVPFTLPDQYSYMRTIGRFLLADHSRHFNKSWKGERIAKSVALAYLGSWIPVSLQKMIGSMMNCRIFPFLYSKRTSVLFGAGACSSTDLWDAQGDKVKVTEQILEEWNRLNLNAVICPLFPFPAPPVNLPGLLPTAVVYAMIWNLVDFPAGMVPFGRESGKNIDSYDDEGDNALKMAKKGIKESIGAPIGVQVVSLPFKEEVVLRVMCELEKFSYKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLW4</accession>
    <name>A0A1D2MLW4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Syntaxin-binding protein 5-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_12756</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat L(2)GL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000888">
        <property type="protein sequence ID" value="ODM93928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLW4"/>
    <dbReference type="STRING" id="48709.A0A1D2MLW4"/>
    <dbReference type="OMA" id="ICITTEK"/>
    <dbReference type="OrthoDB" id="19944at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045159">
        <property type="term" value="F:myosin II binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15873">
        <property type="entry name" value="R-SNARE_STXBP5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000001">
        <property type="entry name" value="syntaxin-binding protein 5 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013905">
        <property type="entry name" value="Lgl_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241">
        <property type="entry name" value="LETHAL 2 GIANT LARVAE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241:SF25">
        <property type="entry name" value="TOMOSYN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08596">
        <property type="entry name" value="Lgl_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="14">
        <location>
            <begin position="237"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM93928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="302" mass="33512" checksum="1198043AD59EA113" modified="2016-11-30" version="1">MLCMAFLDCNGNPLPTNYEAWRDEAKERSTETPTKGLSTGSRQSPTQLSLDSSGSLGGGDKHFVILVSEKQSRVLTLPSQTCLYKQQLCENSFVIKAEVTTVKDAPCLVCYVSNGHLMILSIPSLRQLVDVDFTPLADLRIAKTFCISALGHGMYLSSPSEMQKFAISSEFYKIMDTLLGELFMEREMPERPKENFFTGLFGGGVRNVDREELFGEASGKSSRSVAKLIPGPAAPPGMEQAQMRAGTLAGEVSKTRMMMVERGQKLGQLEDKTEKMMNEAETFSTAAHQLMLKYKDKKWYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMS2</accession>
    <name>A0A1D2MMS2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 9e2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_12357</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000823">
        <property type="protein sequence ID" value="ODM94329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMS2"/>
    <dbReference type="STRING" id="48709.A0A1D2MMS2"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF102">
        <property type="entry name" value="CYTOCHROME P450 FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM94329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="274" mass="31424" checksum="F29CDE57BAE8180E" modified="2016-11-30" version="1">MSQGLKARMNGEEKRNDFIQLVVEARKGVLKGVGADELSSFEKEAQLSGGVKGKNNYLDDDTIAHAQLIGNFLFCWLHNDRQHRYVFGICIGSASGSSRKIREEVDKKLFKDGDDKEIDYDELNKLTYLDMFISEVLRKFPPLGRLERKCVKEYHDPESGLKCPKDTLVVAPLRALHNDTQYFEHPEKFYPEHFSPENKAKRNPYCYMPWGMGPRNCIGMRFAKIQVQSAIVRLVHSFNLETTENTPLPMKAKAMGFAIQPPDNLELKLTPRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMX8</accession>
    <name>A0A1D2MMX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 4c21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_12268</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000808">
        <property type="protein sequence ID" value="ODM94416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMX8"/>
    <dbReference type="STRING" id="48709.A0A1D2MMX8"/>
    <dbReference type="OMA" id="ETRKHHI"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODM94416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="537" mass="61293" checksum="27FC0C5F5CEA8A60" modified="2016-11-30" version="1">MGSVPTISEQAYSLGQANTIYYYAFRAVCTFILFSLGVLLLRKHKKSNVETLSVSNKRLPGPGHHIFGGIANMLALSNTKIFLKVMESWCSKYGPVFEGVLGTKRVIMINSPEYVQKLLGSKDSNYFDKGFIYEPFKPFWNDGLIISTGAKWKHRRKLLDKHIFSFRTLTSNMQIFNDEADRLVDSLRGTNCETGVKISHLLKTATLNAIIKATSGKLVAELEPEDAGKISFTEMVDMAKPLITKRMTNPWLLIEPIWQMHPLSKVQKFISKMASVQIRKAIDESEENNKVSLKQDLLAEGVPVEGILEETVTLLSAGYETTEGALQFLLFLLALHPNHQELCREEIDSLPGNGDDNIDYRDLNKLKYLEMCINETLRLFPVVFFIMRKLKAPLRLGNPFVKHLFNFIKLLISKMISLLFLEDDLELSAGTEVAIFMPGIHKNPEIYPNPNEFIPERFSQEEIQRRHKFSFIPFSAGPRKCIGYKFAIMEMMCLTAKLLRHFVISTMDKMEDIIVLPHVTLTLEKPINFIFEKRNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MN21</accession>
    <name>A0A1D2MN21_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_12298</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus</location>
            <location evidence="5">Golgi stack membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000813">
        <property type="protein sequence ID" value="ODM94383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MN21"/>
    <dbReference type="STRING" id="48709.A0A1D2MN21"/>
    <dbReference type="OrthoDB" id="8250797at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046920">
        <property type="term" value="F:alpha-(1-&gt;3)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000004">
        <property type="entry name" value="Glycoprotein 3-alpha-L-fucosyltransferase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929">
        <property type="entry name" value="ALPHA- 1,3 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929:SF145">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE FUT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="6">
        <location>
            <begin position="299"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODM94383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="500" mass="57990" checksum="4C932AE0D67A82E9" modified="2016-11-30" version="1">MTRCYLKRSAKTAIFIMIAFIMVFAMIDTRNRYNSYVMSIESDPFHSVATAVRRRDNLRLVLNKTDDASNQVIIGDNELDSQTGPTIDNEAMIGDGHLPSDNGSLTLRFWDLANNSSRGAKTRGIFTESNHLPYLWRPEKPHLSRDDDRVLAQLILAMEATNISLSGRLTKMKTIYLPDSFRWWSKTKWRSPHVLQDEDCPGNPGILRKCAFSQDRDSMDALITVRDAFHTRDFTVPSHVLRFYFMLESPIFSHANLKRSNDLMATFYRGSDVNTPYGKWVYHDPAIKFKTQEKDYAAGKSKMAAIFTSNCHPWNNRMGFVRELQKHISVDVYGSCGQMNCPRYNQRECYDMLKKDYRFYLSFENSNCRDYVTEKLFMNAYENDVIPIVLGAHPEDYKAMCPEKSYIHVEDFPNPVELAKYMKHLANTPDEYNSYFRWKDTGRFIDTNFFCRVCAMVHYADIIPPPERKTDFRWNSDAALTNKLCLPSGAWYWNASSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPI6</accession>
    <name>A0A1D2MPI6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_11769</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TFS-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000734">
        <property type="protein sequence ID" value="ODM94916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPI6"/>
    <dbReference type="STRING" id="48709.A0A1D2MPI6"/>
    <dbReference type="OMA" id="DACDPFR"/>
    <dbReference type="OrthoDB" id="44867at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000001">
        <property type="entry name" value="Probable Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="13">
        <location>
            <begin position="7"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="14">
        <location>
            <begin position="190"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="12">
        <location>
            <begin position="309"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="147"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM94916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="351" mass="38961" checksum="DAF031F083F94C12" modified="2016-11-30" version="1">MSEGMLREVLEIKTKMEGLLELQPEKDKIPQVDPQSAIALLKTLTNMGVTLDVLASSKVGMIVNSLRKKFPDKEVQTLGKSLLKKWKKLIEVPASSPDKSEANAKVEVGEEKSKKRKAHAPSASAGSAPKLLKIKIKEIRKPDYLKDSNEIPEASGTPALNDKASGCNTDKKELQSSSVSPCCSSESDAVRVKCRELLLVAVKGDENYPEGSLDPQELVEQLEDSIFKELKGTGFKYKSRIRSRIANLKDPRNPDLRVMFLEGRISPVKLSTMTAEEMASDELKSLRAQFIKESIENAQLATIPGTKTDLLRCGKCRKRNCTYNQLQTRSADEPMTTFVLCNSCGNRWKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPR3</accession>
    <name>A0A1D2MPR3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_11632</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPR3"/>
    <dbReference type="STRING" id="48709.A0A1D2MPR3"/>
    <dbReference type="OrthoDB" id="10004641at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050457">
        <property type="entry name" value="ZnFinger_BTB_dom_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46105">
        <property type="entry name" value="AGAP004733-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46105:SF5">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BTB" evidence="12">
        <location>
            <begin position="42"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="197"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM95057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="231" mass="26307" checksum="8CF9642F5EB7B889" modified="2016-11-30" version="1">MRGDAIATSSLLQQHPYRINSSEFQRSVIGFLADLHESKAYTDVTLYAQGKLLQAHRIVLAASSGYFKELFSTMDQEQTSSRSARDVKYERSAAVKEEVEEEEQFEDDEEDLLEEETDTLDPSRLLATPLVNMEVLDDSSGNLEEPYDNGLMDEEQSGNVIRMLTRGSDEQNGKPFVCTKCGKTYNSNKSLWRHKKFTCDEKIEFKCSCGKTFSRSDNLRRHVVVAHQNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR00</accession>
    <name>A0A1D2MR00_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000685">
        <property type="protein sequence ID" value="ODM95321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR00"/>
    <dbReference type="STRING" id="48709.A0A1D2MR00"/>
    <dbReference type="OMA" id="IFSAYEQ"/>
    <dbReference type="OrthoDB" id="432381at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052775">
        <property type="entry name" value="IUN_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190:SF1">
        <property type="entry name" value="SI:CH211-201H21.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190">
        <property type="entry name" value="SI:CH211-201H21.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="2">
        <location>
            <begin position="91"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="434" mass="47919" checksum="5124105C84A6076B" modified="2016-11-30" version="1">MPISHLLTDSFFQEQQKRVQNIPSLQHNSSNLHMHFEENVTAHRELIETDIYGSPTRNHHDEPLKHTVKDASNNSVNFALATSSEVSENVVLIDTDGGCYDAWALFLALASSGKNLRIVGITTVNGCTTVNNAVKNVSRVLQTVGKKIPVYQGADSPLLGTSGSKTPRPPFFGSDGFGDPTNLPFLPESPAVEAEPAAVGIIKLAEKYKGRLSIIALGALTNLAMAVKLKPKLKNYIKEIFILGGNSEGVGNMTVASEFNFFVDPEAAQVVLENFTSCPLYILPWETCMRSAASTYDFRMNSIGKLGTPAIHLLNKIEETILSKYHDKWIAPDAVVVACFIHRQIMSKTEQYHCTVELQGAHTRGMMVVDKNFVRQKPANVILISEVQLEDYENMLMAAMGGHYLQDKAIPLIRSQAKQEHAPISYLNVDQNYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRM2</accession>
    <name>A0A1D2MRM2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein Wnt</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_11038</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Ligand for members of the frizzled family of seven transmembrane receptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
            <location evidence="1 9">Extracellular space</location>
            <location evidence="1 9">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Wnt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000640">
        <property type="protein sequence ID" value="ODM95646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRM2"/>
    <dbReference type="STRING" id="48709.A0A1D2MRM2"/>
    <dbReference type="OMA" id="NDHMPDI"/>
    <dbReference type="OrthoDB" id="5945655at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005109">
        <property type="term" value="F:frizzled binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060560">
        <property type="term" value="P:developmental growth involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007517">
        <property type="term" value="P:muscle organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19333">
        <property type="entry name" value="Wnt_Wnt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2460.20:FF:000001">
        <property type="entry name" value="Wnt homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005817">
        <property type="entry name" value="Wnt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043158">
        <property type="entry name" value="Wnt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018161">
        <property type="entry name" value="Wnt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027:SF91">
        <property type="entry name" value="PROTO-ONCOGENE WNT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027">
        <property type="entry name" value="WNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00110">
        <property type="entry name" value="wnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01349">
        <property type="entry name" value="WNTPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00097">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00246">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0879">Wnt signaling pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM95646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="375" mass="42560" checksum="3BA2A39D6EB3C920" modified="2016-11-30" version="1">MKIYDLIAPNYCKLIMGIAKVGEPNNLIVNTIRGGANIGNNYLEPAVQAVLRKKQQRLVRENRGVLEAIAKGANDAIVECKHQFKNRRWNCPTKSFWRGKNLFGKIVEKGCRESSFIYAMTSAAVTHSVVRACSEGSIESCTCDYRLHNKYSRVMTPDQNWKWGSCSDNIEFGYKFGKDFVDAGEKARDMRGTMNLHNNEAGRIHVQSLMRRQCKCHGMSGSCTMKTCWMRLPHLREVGNSIKDKFDGASRVQISNAGILRDVRGGGRGRYKFQLKPYNPDHKPPTKKDLVFYEDSPNFCERDPRYGVSGTYGRACNVSSMGVDGCDLMCCGRGYTISVKQVVERCKCTFQWCCQVECKNCTVTRTFYTYIKITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRZ4</accession>
    <name>A0A1D2MRZ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000635">
        <property type="protein sequence ID" value="ODM95678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MRZ4"/>
    <dbReference type="OMA" id="ENESACP"/>
    <dbReference type="OrthoDB" id="8251770at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="950"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1506"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1586"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1685"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="838"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="880"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1196"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1238"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1286"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1325"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1589"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1615"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1637"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1688"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1721"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1760"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1789"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1863" mass="206412" checksum="486D7F3C07ADD7BF" modified="2016-11-30" version="1" fragment="single">MEVVADQTPTPTQQTEEVEEQDGEESEREWWRPPVPPETYKWEEVRRQRQKGGYPWTHLDKDEEIDVDDYLDENLYEPVNPPPLYGNESYLSKDLQVPKAEERTIEIPPEIEILTSEGLDGLDKPDPHDHGFDGDREWQNISASEDEQGTANRSSFTAGLRKDAGEPRPTTPKSVGFADEPITHECPDEPDQEVPDDMQTDAEPGSSVKHGRRKTPFDILKSKAADAADHVKQKIRSAIPTRPKVKEGTLKKGRRRGKAKHGETEEDEQEVPEDAEMKDAVEGGEAAEQVEEAMDVSESKAGEEEGAADEVEESKDEEKKRQKAEEKEEKERKKAEEKLAKQAAAEEAKKAKLEEKLAKAREAEEARQAKAEEERKKQEEKKEEEARKAAEKAAKEEEARKAAELKKEEDAKKAAEKAAKEEEARKIAAAKKAEEDARKAAEKAAKEEEARKAAEIKKAEEEAKRIAKEEAKKAAEAKKAEEKAAKEEAKRVAEAAKEEERRAQEAAKEEERLAAAAAEPEKVVEEVQEQTMDTTEAAAEGEQPAEGDGGEAGDEEGDTARPHTPSGTTKRRYIKQRKNPIQLPQIPNPITMLRNQVEDYRNKLKRSRTPPRGRGQRKQRRSRSADASRSPPREPGDEEEEGGEAAAPAEDTAMETQQEEAAETKATKSETKPAEAETVKEDTQQSSAPAEAEEEKPPEEPATHTGTITKRRQPAAKEKLDKLGAHLKGIGAKTIGVASQATGAIGNTMKVVGKDLQKLGSKGIEKCQSAVGEIKAKQSAAKNKEVQGEEVEEEVIEEIPPPEIAPPKRTFRFKRRNESQEEGDEDDEHFYENAQEISQERQQREDDLQRNRLLGRADRDWESPMDRAQSRDMSEERFSGNVSSRDSPPGSSLASSTIAPPRRPGVLEEIDSDEFFLRERGISEGEDEEEVNRFLVEELRQAFRPTMSNALAGFDLEPPLVPPPRPDRPSRKPARQSAEEEATPTSYQTFPPERPKRKGPQGYVSKFMKENEGEEEDEEYMGSNEEVRGSSDDMKEELEEGDEGIQMVKDKLSEIDRELDEGATSSEPPQQPTTPLDDYEDDGRYEPISDKPVKPLRTKKKAPKRPPTPPSFYYNTIAANEWLRELESQVQDNEPAAPVRKRRGSGKSGSQPPSSTGDEELKPKVEDTPSTEQASDTITAATEAPRAESAHEGSSFAGSSQVSGLNENDYIDEAGYAIVQKDNLPRTVPRKKKKRTNADSAQGPSGSRQGEEAFMSLPHRQFQAVPPSRPNRTYSTLKPKRPPRSKSGSRNSLESKSPASSRRGGGAETDEPRPSTAIGIMQGRPLPPPPRPSRSPAPLNDLDQSSIEQALGVRHYANFEELEPRQVEEIFTASNIPLLGPRTEVLATRPTEVDIACQTDPVPDDEFLLGLSAPESPVLDSSRISTQSQPTQPPPPFVFPTRLHLEQLEVDFLRVNDLTAQSIRVEHLQTPQLEVHSLTATGPLVVSRIQTQSLSSEEVNCSRLSSDKVELPSVPPPSFYQLSSPDDDVLKPGSEQELCLKTEEQEEKENESACPPEFLESVHNLMGYVDSTNDMKSSHVAEKILDKQLNVTESTQTTNQPKSNKRDASVGTHNTPIVTRQTVVPQQQQNNLSQEPTQKKEPPKDEGEVAVKQQLCITTFPVTARGRNEEVEEETVVVGSYTLPYSYIPTQSPSLSRTGSTEGSQQRSTEPMSTPLPPPTSDSTPTGTPTLGPTSVAEGDVLSVKFSIPVERGSTGQGITGTRPTPPRSQNASHQSRLQDSATSQAESLKGEAEKPEKLHQARQPSPRLLTCKSFKIFTTSQILSANRATPPLRPTPHWRHLLLPSHPLTASSTLHQHPHPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS24</accession>
    <name>A0A1D2MS24_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aldose reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_10779</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000610">
        <property type="protein sequence ID" value="ODM95887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS24"/>
    <dbReference type="STRING" id="48709.A0A1D2MS24"/>
    <dbReference type="OMA" id="LWNDSHQ"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000006">
        <property type="entry name" value="Aldo-keto reductase family 1 member A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="319" mass="36396" checksum="2C43A20205BE3E9C" modified="2016-11-30" version="1">MTHEKVPKIELNNGTVIPAFGLGTWKSLPNQVAQAVKDAIDIGYRHFDCAFAYQNENEVGEAIKEKIEEGVVTREDLFIVSKLWNTFHRPDLVEPSIRKSLDNFGIEYLDVYLMHFPMAAQEGDSLHPVNEDGVMIASDVDYLDTYIAMEQLVEKGLTKSIGISNFNKSQIERILENCTIQPVINQVECHPYLSQEKLIEYCKSKNIAVTAYSPFASPDSPFRQPGDPDLLQDPVLKSIANKHNKSVPHICLRWILQKGLIVIPKSVTKSRIAENMEVFDFELEDEDMVNINCLNRDWRAVTAKIMGEDHKYYPFNDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSC1</accession>
    <name>A0A1D2MSC1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Myosin light chain kinase, smooth muscle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000633">
        <property type="protein sequence ID" value="ODM95694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSC1"/>
    <dbReference type="STRING" id="48709.A0A1D2MSC1"/>
    <dbReference type="OMA" id="DNITNCC"/>
    <dbReference type="OrthoDB" id="428111at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000107">
        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="28"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="130"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM95694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="223" mass="24990" checksum="581B87D98C9BC994" modified="2016-11-30" version="1" fragment="single">MSTETDEMEISIEAPLMQRPASRDYQDPIFIQPLKDLIVNEGDKVVLECKTTGRIKKLMWLKDGLEIVNNPDYKTDFLDGSTAMLTIDEALQEDSAIFTCRAFGEGENVMVETSGRLTIREPVTSLLLPPQFLPHAPVSIGEHGKSHFLQLKVEGNPLPTVMWFKDGQCIDTSPDYIITFNNGLCEIQFDELVKDMDDGVYICVGTNKLGDCETQVELQIRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTB3</accession>
    <name>A0A1D2MTB3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000574">
        <property type="protein sequence ID" value="ODM96138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MTB3"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376:SF235">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="932"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="965"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="1071"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="483"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="614"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="777"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1142"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="252"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="777"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="794"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1142"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1162"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1176"/>
            <end position="1196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM96138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1312" mass="152291" checksum="68A3B8DAB581C908" modified="2016-11-30" version="1">MAFKPEQFVVKVEPPQSEDEWEGQNQDEDSLLTSADSESFGGGTVIKIEVEPTTYSSSDAEENCDDDDGSRSPQEENSDDDGDWKPEKKPDIRKSKAGRPKKKSISQESKKYGRGTSNKGLTLEELKAKRALQARQRRQRKKLEMTEEEQERKVEERKYAKATSNKGLTPEEIRAKKRDMQRKRRERIRAQLTEEELEELKRKEREKKRLSRARFKLEEEGGEVESERRTRPKGSFAESASEDDFVKKEGKDDDDDYEPHEDSEETPRKSRKDMSRAELRKKWREEALARRRRKRAEMTPEQREEVLRKERERKRELRGSSSGSGRGIKKEGGLSSDAQERRRREAEARRLKRLAMTPEQKEEAKQADKIRRMMRHAALTEEEKAERKMKAYMQVTAKLSTLSKEELEEIKKKKAERARLRRQKMEKSERRVLYERSKRWRQNLQGEKLERAKEQLKQAYYRKMERAKNDPELMAKIKREWKQGYERQKDPTRKKRLKPGETEEMRLERRREKKRQDMKKFNLKRRLERQRLLESGVPLEEIRTREETPEQRERRCLRNRMYRAKQTLRDQLIRQGVSQAVIQERLAELVANWVPSRAEFRPYKPKALKPLEPEDLKILAEGPKPKRKSTESAFSTPSKAACITQPDTKPLTNLTPFKTPSTSTVHPVPAPTSYSSSSSGAHDLSYQHHQPSNTLSNYQSHFLNYAPSTSAPTPSTSSAYHQNHTPFFSAIDYEAQSYCSSSQDDCSAASIPPHHLLNHLLLQFSGNLTATSVSIAHPSPSLSPTSASVLAKPKSNRGRPRKSRAKPKPPPGVPVPQIFRGGKHANTVRDQMCQICGYRYSKFYIADHMLCTHNPNYQNGKCVLCNAEFSSGRKFYYDHWIRVHKVKEIETNPDGSPKEMYMCDECGAGPFYKKGTFYTHKHYTHGNYETDVPCEHCKKIFKTARSLYTHIRRYHKDVKKSVAFWNCLKCEEAFSAQTDLKEHVKTKHPDSYFTCPDCDVFKYTEANMKFHWYKCAKRDKSKEVKEKGKKEDEIPSIEKIQVPCEICEIKVQLSSLTRHYKDIHGIIEELFKCLKCPKTFKRREFWVAHLEMLHSLDIDDIRDEIYKYNVSDRSALEIKNKEGGHKGLPGHLWAGGEWLKKKKKTGGKRGRPPGRGRVTGRGGKRTTTRRRIHSSDEEEDEEKFNLDSESDPEFVLEEPKISTSRRGRRKGRAVRFSGEDIETEKRLVISISPLTEEEIRRFVGKKAEEPSCDDDNAGKEIEIEDSASCEAPKVKVEVADNEVADAVSPLALDFELGESVEESLPIPDFFME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTQ7</accession>
    <name>A0A1D2MTQ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lachesin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_10222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000538">
        <property type="protein sequence ID" value="ODM96457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTQ7"/>
    <dbReference type="OrthoDB" id="10012075at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="61" mass="6804" checksum="7AC8FD39BF95931F" modified="2016-11-30" version="1">MSTSAVDGPVLNLTRINREHMGEYSCVADNGVTPHKQRAFIVEVHWHTFRSFIKLPVGVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVF2</accession>
    <name>A0A1D2MVF2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aquaporin-12A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_09778</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000492">
        <property type="protein sequence ID" value="ODM96891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVF2"/>
    <dbReference type="OrthoDB" id="9894770at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051883">
        <property type="entry name" value="AQP11/12_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21191">
        <property type="entry name" value="AQUAPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21191:SF16">
        <property type="entry name" value="AQUAPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM96891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="19650" checksum="FFA0E41122262E43" modified="2016-11-30" version="1">MKHIEGIGTEGNDYYRRFEFVMVLIWSEAFGALLAYGYLVNLIWANAHLWEFWDKENNYHFHLFKTANEWQASIAAYPAVAAFVEGIFSLAQYILPIFVTKVGLEGNPALLLINSGKAIFAGIGAPFTGGYFNPIVAFALEYKTRGHTLLTKTMVYWIAPILGTIAGIACRKKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVW8</accession>
    <name>A0A1D2MVW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000461">
        <property type="protein sequence ID" value="ODM97223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVW8"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904632" evidence="1">
        <location>
            <begin position="32"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="268" mass="29983" checksum="8AB8EFD440847AAE" modified="2016-11-30" version="1">MRVTFLPTPQFRCRVLLFFSLISINSDIVKSLSEMQPCHDSTKGDGKHTNITLTNIDDALDSLYKAIKTNASFEEECNDSVEINSTEISLVRLMEKFEIRRSFYSQGLWGNCAEDGAQKLIEDINTLKNIATGDNGTSAGMSITLCDRDQLLECHPTFKKCQCITDDRDFRNIVSEYWDNEEEISAKDAKGKSLGRDGCVLVTGSNCPVANESPFLCIPGSNCLTKKGLKPCVLHNLRDSISSRSKRSVSSRYSFFKDTYPTIHCQCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWL5</accession>
    <name>A0A1D2MWL5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Annexin A13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_09235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000441">
        <property type="protein sequence ID" value="ODM97447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWL5"/>
    <dbReference type="STRING" id="48709.A0A1D2MWL5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032509">
        <property type="term" value="P:endosome transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF233">
        <property type="entry name" value="ANNEXIN B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0041">Annexin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904656" evidence="4">
        <location>
            <begin position="18"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM97447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="374" mass="43177" checksum="D5E838C07A96AEBD" modified="2016-11-30" version="1">MLVVISFLLILLTCVCSESAPNELDDVATEDATFINTILEDHDIQFKIARLATSRSYSERIAISREYERLHNTSLIEALLLTSLSGETGKLIQGLFSTSAEFYAMEINRAVIGLGTDEKALNDVLCCLDDLTVDEIRYEYRRLFGRSMDEDIIDDVSGPYEQFLGDVIAMRRLPWANARQIALMVTDHYINAANGSVPDPWFFSRSPYATIRKVSNHLQNVIGMNFPDYFSILRDEYRDDLTQLLCAIASYSQNPLRYYTNLLWNAYEEGDNKRLTRIIVSWTNSKRKLEYLMADFELLAKTRRTDAWMIQAYPSDSEPLHRYIIQKLLFGEAIEADVKANMESITERFPAFFPIREDFRNHLRDIVKVAMFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWQ7</accession>
    <name>A0A1D2MWQ7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">O-acyltransferase WSD1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_09213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000439">
        <property type="protein sequence ID" value="ODM97476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWQ7"/>
    <dbReference type="OMA" id="GMICISS"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009721">
        <property type="entry name" value="O-acyltransferase_WSD1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650:SF1">
        <property type="entry name" value="WAX ESTER SYNTHASE_DIACYLGLYCEROL ACYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06974">
        <property type="entry name" value="WS_DGAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="O-acyltransferase WSD1 C-terminal" evidence="2">
        <location>
            <begin position="377"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM97476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="513" mass="58126" checksum="DEAE933B52181EAF" modified="2016-11-30" version="1">MGSGISHKLKLVEQSTSQFLIKMNKLVFAVEQLILNSTFIFITLSYLIPWWIPFHIYRWVVINIFARYYQSEDFGKALSPYDSIWADEDFTKYTPKNSLICTFTLEGDIKLEEFRSIFKKNVLEAELKSSASKVRYPELQQFQVNYMGHKFWKNDPNYKIQSHIFEVSHHPACQLRLASVHQDALNKLFTPKRSPWDVTLYRNYENDDGTDKTLVLARFHHSIADAKSIMKLFVECLGQQKLTTAQPQNVEEKGFINELFDFLNFPCQYVFQIVPFVIKSVASFHHPWCTTVFVSDSQSFSHVVGLTEPLSLEDMKSVAKKFGERVTSSSVMMAMITGAIGKMGKRLREEEVHCAYILPKPDHPPTLGTHACAGGVMLPTTEVSPEKRLFKCQKLFSEMKASGIERYSNFLVWQLGTLINVVRKLIARNICNPVGITNIAGEAKGFSVGKHECSEFIFSAGTLTGCAGVAFCTSSYKNKLRIAVMAKESILDKIGVKKLAAAIGEELEILKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWV9</accession>
    <name>A0A1D2MWV9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">cholesterol 7-desaturase</fullName>
            <ecNumber evidence="14">1.14.19.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_09143</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>cholesterol + NADH + O2 + H(+) = 7-dehydrocholesterol + NAD(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:51644"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
            <dbReference type="ChEBI" id="CHEBI:17759"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.19.21"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:51645"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>cholesterol + NADPH + O2 + H(+) = 7-dehydrocholesterol + NADP(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:45024"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
            <dbReference type="ChEBI" id="CHEBI:17759"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.19.21"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:45025"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Hormone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Steroid hormone biosynthesis; dafachronic acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cholesterol 7-desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.21" evidence="14"/>
    <dbReference type="EMBL" id="LJIJ01000434">
        <property type="protein sequence ID" value="ODM97536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWV9"/>
    <dbReference type="STRING" id="48709.A0A1D2MWV9"/>
    <dbReference type="OMA" id="ENAADPY"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="UniPathway" id="UPA01020"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170056">
        <property type="term" value="F:cholesterol 7-desaturase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045605">
        <property type="entry name" value="KshA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19298">
        <property type="entry name" value="KshA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Rieske" evidence="17">
        <location>
            <begin position="74"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODM97536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="404" mass="46779" checksum="3EE7BC8DF96BCDA6" modified="2016-11-30" version="1" fragment="single">EYLAIAVIAAAVAYCVWLLFYRPFDFFRDFTELGFEQISNKRKYGSDAKKRYIINECRNRREIGDLPPVYPNGWFAILESDEVLKSTVKEVDVLGLNLVVWRGESGKCYVSDAYCPHLGAHLGVGGLGNFEGCSGKLVSIPNVNPVPPFANLKMWPVFEAYGFVYIWHHAENEEPSWWPDAVPEVESGQWKYRGRSVFRVACHIQEIPENGSDSAHFNVVHSSPFTTGSNPDESQLKKNFIKHVWSASWAPNSDLDRKHEALMRVTHFIKLFNKISCFHFTVDVHQIGPGIVLMYFETVLGKGILIQNVTPLEPMLQRVMHRFYSSPTFLHPIALLIMYGEVVQISKDIRIWNRKKFLRNPVFTKEDKQIRAFRRWYSQFYSENSLKWLPNTGSTLRHEKLYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MX52</accession>
    <name>A0A1D2MX52_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BOS complex subunit NCLN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_09149</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nicastrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000434">
        <property type="protein sequence ID" value="ODM97538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MX52"/>
    <dbReference type="STRING" id="48709.A0A1D2MX52"/>
    <dbReference type="OMA" id="WSTSRHC"/>
    <dbReference type="OrthoDB" id="5913609at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016574">
        <property type="entry name" value="Nicalin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31826">
        <property type="entry name" value="NICALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="12">
        <location>
            <begin position="213"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="533"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM97538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="554" mass="60519" checksum="776D16ECD51F6158" modified="2016-11-30" version="1">MWFDQGNELFDVCRTSFFAYLLLALPIFVSISPTCLASKEFSAFRLQQFELHGSSYGTSGSLLNLETRILPGSPMVSSPRRCYVVRLVDLTVNMYKDLLTAQVAGIVIIVPADLSSISGEIRDQIQELEQAMLADFTTVPVYFIQETQEVNQVYQTIKESAESLGAASTALQTLFHHVHGNGVQLVSSLGSPKVMSDAQILSIQGALIGTKSSRSFPILISTHYDSMSPAAELSFGGDANGSGAVSLLELARVFSHLYSTRGTQKYLEDQVDSSDQSDLQDTRLVVCLDSLTTNPDKLFVHVSRSIREGTMLNTFINNLKKAAIHLEPSLTVEVIQRKIRTENLLSWEHEKFHLKKINAITISSSESPSLVKSSMLDVKDNVDTENLAAKTRIVAEALAASLYNVTEVGTAFSGSLGVSDESVNSLLEFVTSQPRSAQLLAGKQNKFVQSLRNVLARYTHETSLFTMKPDKRDANLVFYDGTSGTIVAYDVKPAVFDLVLSLAIAAYIGAVYLAIKNFSLIYDSLSYKLSSSNHHTSSTTNGTSGSHTSKVKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MXC2</accession>
    <name>A0A1D2MXC2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_09217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000440">
        <property type="protein sequence ID" value="ODM97454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MXC2"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904688" evidence="1">
        <location>
            <begin position="21"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM97454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="94" mass="9707" checksum="98EC30626E64FFA0" modified="2016-11-30" version="1">MRVTTSILVLIGVAIGSTAAQDCWTTGCQPNDWATKGCDQYNRDESRRERCWDNRGVEGNKYTCCARTGGGGGGGGGGGGGGAALVNCNEFSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY80</accession>
    <name>A0A1D2MY80_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000390">
        <property type="protein sequence ID" value="ODM98006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY80"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="68" mass="7428" checksum="98E5146A1611BC98" modified="2016-11-30" version="1">MYVFLHILCPSIKNVVMAIRAKKKNRKAQQLKKLAGGGNPKGRGSPRGRDVNHSRIGELEKGCAPVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY94</accession>
    <name>A0A1D2MY94_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peregrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_08671</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000389">
        <property type="protein sequence ID" value="ODM98009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY94"/>
    <dbReference type="STRING" id="48709.A0A1D2MY94"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000007">
        <property type="entry name" value="Bromodomain containing 1, isoform CRA_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="314"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="368"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="11">
        <location>
            <begin position="655"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="11">
        <location>
            <begin position="800"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="11">
        <location>
            <begin position="941"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="76"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM98009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1032" mass="118428" checksum="3BA92191C58303A8" modified="2016-11-30" version="1">MPGRRKTNRFSRYLQKRSSETKEETVKESSSSAAGNLQEGDEEDDNVGEGKVLLVIDGVKFCEDVLTDLDYLMSGEENENKVPEGRPSELLEQDVNPSLLAVPPSVSTPLKRSSPLSPTFQENVLKSTRSSRTPQQQQQGVESFPLVATPPKSDVVTRRKRKRLRISSETESEVQEEHSPAKKHRQSRNPIPTPKQTSQKVTVKPTSSDDTFALPVANFRILEDYKLSDAVPPDPDIYLTTTVMSKEDRCKDVQYELDEQDIAWLYDRNVWRAMFKLRPVAPEEMELLIDRFEKEIYYEMHNSGLMEAGEAEEDAVCCICLDGESDNWNQIIFCDLCNIPVHQDCYGVPFIPEGSYQCRRCSISPNLTVECIFCPNKEGAFKQTVDGRWAHVVCALWIPEVRFSNASLVEPVDDIDDIPASRWKLSCFLCKTKGVGACIQCLSQKTCYTAFHVTCGQAAGYGMKLEVNENTEVGVKLVPSCDKHTNPAERVLTMKKVEAIDRVMEEKRATARKCAKLMIRQERVNVVKELIQFHGRDAFVKRLKCYWKLKRDSRSGAPLLRNLELMWCETQYPPQPPPLCIRGPDGKLLVEDTMEYFVNCLKNYREDLTKIRTYAGVQKLYSVNFKEFIDVTCQIYALKLQSSNPIYHEVIKKLDKKDTRGIFSEPVLEEDAPDYFSVISQPMDLSTMEKKAKDGQYQNLYELEADFNLMIDNCITFNDETTMFHKTALKMREHGKKIFQDARNKSVKQLGLQELFNEPMPSNAREVSDEAKTETKVKLEESVSSSVLQPMLNDLLERLAKNDKQEIFSEPVDPDEVPEYNTIIKKPMDFSTMRNKINNQKYSSVEDLEADYFLMLDNCMQFNEDHTSYFKLAVKMKKLGERIFTDIKPQIPSLMHVVKDEIKVEKDEDLNEDPAFKQEHVEMQQNSKEHQIMVKVLKELIALDEQEIFTEPVSIEDVPDYLTIVQTPMDFSLMQKKQSSGEYSSLDDLEKDFNLMIDNCKLFNGNRTKYYKIAVVMKEAGDAIFINARENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYC9</accession>
    <name>A0A1D2MYC9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lachesin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000386">
        <property type="protein sequence ID" value="ODM98049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYC9"/>
    <dbReference type="STRING" id="48709.A0A1D2MYC9"/>
    <dbReference type="OMA" id="VNQISWI"/>
    <dbReference type="OrthoDB" id="10031887at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF45">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 12, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="65" mass="7747" checksum="A0155A78B1F370CA" modified="2016-11-30" version="1">MPQIFFGSLQISWVRRRDWHILTSGKTTYTNDERFHVLHADGSDEWTLQIKYVQKRDAGTFECQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZ49</accession>
    <name>A0A1D2MZ49_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein eva-1 C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_08600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000383">
        <property type="protein sequence ID" value="ODM98084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZ49"/>
    <dbReference type="STRING" id="48709.A0A1D2MZ49"/>
    <dbReference type="OMA" id="CDSEVIQ"/>
    <dbReference type="OrthoDB" id="5970528at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22829">
        <property type="entry name" value="Gal_Rha_Lectin_EVA1_EVA1C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.740:FF:000003">
        <property type="entry name" value="Protein eva-1 homolog C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000922">
        <property type="entry name" value="Lectin_gal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043159">
        <property type="entry name" value="Lectin_gal-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46780">
        <property type="entry name" value="PROTEIN EVA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02140">
        <property type="entry name" value="SUEL_Lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50228">
        <property type="entry name" value="SUEL_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SUEL-type lectin" evidence="3">
        <location>
            <begin position="72"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="164" mass="18286" checksum="DFF6C22E6382A8E2" modified="2016-11-30" version="1">MQIRMALASFVKTQPSLHSILIRKLTLPFVILRASTTSVMYKAMADERKSNLYAQYNGSYNPTCSEFKSVIGCDSEVIQLKCNRSSRLAIYSANYGRTEYESVQCPQPKGVSEESCLSSFATENVMQMCHGKRRCALGVNPSTFGNPCKPESKMYLKVIHTCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZZ6</accession>
    <name>A0A1D2MZZ6_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative treble-clef zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_08053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000339">
        <property type="protein sequence ID" value="ODM98617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZZ6"/>
    <dbReference type="OMA" id="RIDFCPS"/>
    <dbReference type="OrthoDB" id="6506929at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026049">
        <property type="entry name" value="C2orf42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029269">
        <property type="entry name" value="Zf-tcix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13518:SF1">
        <property type="entry name" value="C2ORF42 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13518">
        <property type="entry name" value="PUTATIVE TREBLE-CLEF ZINC-FINGER C2ORF42 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14952">
        <property type="entry name" value="zf-tcix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative treble-clef zinc-finger" evidence="2">
        <location>
            <begin position="15"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="632" mass="70169" checksum="702B370B52E63733" modified="2016-11-30" version="1" fragment="single">MPQRQDKWKDLFAGLGRPTKRGIRKCPKCGTVNGTRGNSCKNKACDVVFRNNGASKKTSTEACKLTLNIPGLQIFSVRLRDRGPDYRNFVQLPLSPVSDDKHEANPYSQCYVDTCRRNKVVTCGHIEAAQRCFSESQPLSIDHSTISSPNIPQDQQQLLSIYLQEANAVVVQRVSKTSFVVRSETTLKHQLGYLHIMFFKQNKEDGTVDKKFLCTCKPYKVQQNRDNETQTNTTDGLDIGSKFCVHYHACLCAFASDANLSSEFACFLAQANPDCTPTLFNQLHLVTLPQGTGSTLVDGIDTSNPMTVQGLEGVLSDQIIVTNVDDSLSFGDASGLDLDDGNSQVCQIFTNAQNAIQLASAFSNSENMHQTVNIANTACLHHLILVDQKKTSCFNDGTMEVATLSATHSVHPLTVTNHYEIANKPSPLKGSIVNKGFQSQTITFTTPATTTVSPTPTPPLSSEHEFNSPATVDGFDRWLAQVNERLNTAMNFQFSGKPEPIVYFISSEFFECLKDRITSGVKKKRLPNQTVIIARTHKPPAGTFTKHVWKITNLTHVQQIFYNQVELMAYFKSGPPPNETDRKNQHIKPHLHSTFLKVGKNDPNAIDNVPFVIEWIPDILPQSKLGELTLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0E6</accession>
    <name>A0A1D2N0E6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000332">
        <property type="protein sequence ID" value="ODM98710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0E6"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904837" evidence="2">
        <location>
            <begin position="24"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="324" mass="36500" checksum="2F37E788D3BC5793" modified="2016-11-30" version="1">MLKILIFTAVSSIFAAAFSEITAKEISAAIVPELKVVGVLGQSVNITCKSERDYKLRSCRWERLNTGVNRYFININSHGISEGGLEEFHAAMWECFLIGKPVDHSWIGRLTVELTRFEPYFLNTADFNITYDEASSAAQNITCCVANAAKIPVHFQLDFGNDTFSKYDLIRKEKDITCATTTYKFFPQNNENEDSYIQIKDNEKYAMTYVSLEGDNYRATVKVKNVNEEDLNRKFKLRISNAHGDKELSFQIVSPDPGDESDTYWLMILIGIGAMILCLVFFAVLFVIISKKLNSGGYAPTVVRYSNQANRDSEIATVNSVGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-11-27" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0H2</accession>
    <name>A0A1D2N0H2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000322">
        <property type="protein sequence ID" value="ODM98786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0H2"/>
    <dbReference type="STRING" id="48709.A0A1D2N0H2"/>
    <dbReference type="OMA" id="HSIQNDG"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM98786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="375" mass="42150" checksum="B68C7CA23A4A44B8" modified="2016-11-30" version="1">MNKYRQLDSFIILGTFLLTISTVVEGAARMKQIPLRSHKISVSGHSSGAVAATQFYLSHSDLIDGIAVFSTMQYHCAGGGIVRLVPCLRGRKNVSESVDKAREYDRDGLIDPLENLKARKHYLHHGSRDVIIHFDNGVHAYEFFKQFSDNVRFHQSDSNHAVPTKHCGIHCMYGTVGSGCSKCDFSAVFEGLNYIYDGTLQEPTATTCRAAQPNDGIKLVDQSEFLFPFDSNVSLNPEAVLYTPRQCRANSSMCTLHVAFHGCRHSIQNDGMEYIKCSGYIEMADANNMIVLFPQIKQSRVDTITLFHCWDLHGYTGPLYGTKLGSQNQVVYNMIRRIMNGYSNDNEIRHWKPLAVVNEVDDEEDHNKKKVVAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0S9</accession>
    <name>A0A1D2N0S9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Helicase domino</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_07813</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000315">
        <property type="protein sequence ID" value="ODM98872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2N0S9"/>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140096">
        <property type="term" value="F:catalytic activity, acting on a protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010557">
        <property type="term" value="P:positive regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000529">
        <property type="entry name" value="helicase SRCAP isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.850:FF:000012">
        <property type="entry name" value="protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1 isoform X3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSA" evidence="16">
        <location>
            <begin position="720"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="1114"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="1854"/>
            <end position="2004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="165"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="309"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="501"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="618"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="885"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1503"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1557"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2036"/>
            <end position="2061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2455"/>
            <end position="2481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2715"/>
            <end position="2740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="165"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="461"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="502"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="549"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="564"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="618"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="894"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="917"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="966"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="995"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1013"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="2462"/>
            <end position="2474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="2715"/>
            <end position="2724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODM98872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="3016" mass="333856" checksum="B514698124896A7D" modified="2016-11-30" version="1">MGMRVTMMGEVVEEATVTQQQQQQSNQQQSQGTDVAFPTLPVNNAAEDDDDEDDEDDAENYHQRLCSLSMRKKSGGGGGVSSVGGSSSVASDAGDIKSSSSFSHSKLYRLINLPRRHLAKRRTLVRKHRQVLQGISLKVQLKAKREFEVKFLEAVYVRNALFQSLPHSSSSTSSPSLSGGSGTGASSLGLSLSSPSSSSQHLGNNAGNSSSSSSGGKSVVGSDSSNTSVHHGKLFEQSDEKGDSSGKDALQVDDSDAVVPQCSAISEYRPYSGVWFNCLKSKAMNKREPDHLLKTTYDNYVQNEAKRLWLSKQNKKTKKGSKSPDTTEPTSKSSEAPCPPASGEVEQSGVTPSPVGGSSSSSSSSGPSKPLSDNNASKLVASTPSTSASLSPAVTAATSVSSTEVAIVPQTAGAGATTAQQRASSPTSLPRSRASLVEKEKDQEQLGAASSPLRREESSKTTELSINPSTPSAVSSSDEITLCQTVVTCISKEELEKGRRPNANYLSTTLSSLNTNNNGGGGGDASGGNSSSSAPAKKQGSDVSKPGSVLSSNASDVSVKSVISENTDSSSSASTNVSCSSFNDKDSTSILSVATNANNPSMSGNIPNLTNTLALALNHNNSNNNSSATNNNSNSNHSNNNGNNSNTNNNNNNNSDTNASSSSSSSNAANHTGAPTKSNRKLGGGPKPPKKYSEKMKAEASVLQRIAELQKEGMWWEKRLPKVWEPAKVKSHWDYLLEEMHWMAADFANERKWKRNAAKRCARMIEKYYHDKDLKRQKAEKEEEARKRKTASNIAKLVRQFWSNVQTVVEFKEQTIIESMRKKALDQKLSYLVNETEKYSEIVAQTFTAIAQKTGIESVEGKEASDVPASSAQASSVATTIVKEEVSSPAPVTEENDDEFVPPSDSESDVDDTIAEEEAKEKVDSSDHVHEIQELEEENNMSIEDLLAKYSKYLHDPESYQEPQAPQQPPPPPPEPKQEPERRITRGRVQPARQLRSTARTTRLQAQTKVAESDIETDVDDDETTCTEEDSADESASEAEKTNDDLASLLKSISAADTDQKMTTEDETNKLADLAESFKPKGNTLSSTTVVTKVPNILRHTLREYQHIGLDWLVTMYDKKLNGILADEMGLGKTIQTIALLAYLAEERGNWGPHLIIVPTSVMLNWEMEFKKWCPGFKILTYYGSQKERKLKRSGWTKPNAFHVCITSYKLVIQDHQSFRRKRWKYLILDEAQNIKNFKSQRWQLLLNFHSQRRLLLTGTPLQNNLMELWSLLHFLMPNVFQSHMEFKDWFSNPMSGMVEGSQEYNEDIVRRLHKVYYKAKILMWVSPSLNMYTCIYALFSDFLKVLRPFILRRMKSEVEKQLPQKYEHVVMCSLSKRQRYLYEEFMSRTRTKETLNQGNLLSVINVLMQLRKVCNHPNLFEPRPIASPFQTEGIEYKVPSIVWNMLRGIYQDSFRTCSPLFTITNAKYTYDRDEADRIGELTPLFAYNPDEERRYVVMNYEQRSDGEQPPVKRPKRIINLNKNEPPPCPQLQKPLNFFLSSGKPDAAVKDPEFVEALGGGPRAPNKVVKEEGSQKNKSVLKNHTKSKASGSGESVEKGPSLVDLSDSENSRSSGDSDFEVVVVRKRKTPVTRFNIMSRLAMMGCSVPDFELDYIQERRLRDRKVVVDNLNKVNWSRCRVHSFVGPRLIENCRVVDSLPPVRLTSRRTGVRVPRREHLRDFENNGYFNLGFGEIMKIIRVRQEQPTLFDHPLVMWSTTKHLESVVQTPESRLQELMDVLTRYVMYIPAVSAPSLEGRFYRPPCSSMYLEHVQQLENYRKNFTKPTEIVHPVMSRMLTQFPDPRLIQYDCGKLQTLDTLLRKLKTGSHRVLIFTQMAKVLDILEAFLNYHGHTYLRLDGATKIDQRQMLMERFNADKKIFCFILSTRSGGIGVNLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSEKTVEENILKKSNQKRLLGELAIEGGKFTTTYFKQNTIRDLFTINEKDDVAKRLSTWNTEQTKPLSTVEEEDESTTFDPSDLMKSPEKKHEMQMIECALAAAEDDTDVHAAQTVHAEAEAEMAEFDENVSLDALDEQGKSGPNKFEIEFQQVFERMTDVERYAMRLMESTIDDWSKETVAQAQKDLEEQKLAWELQQQRSVQEIKMDIDDDSCNTEDLLTYSRVESTSQVWVAQFGSCEQDMSFMIYEPPTPPQDEMDVYFDTTHGYLYDYAIMNESQLPPVYVSKHPKKAPTPVSPVAKPGVAAGVVGLRLLRKRRSLPRNLFRKLWTLIMMRLSPKVARREDPIFAPKSLFDRPTPAMAKLRRDLRLQRYSCRPPSASPKATLGPGSITFPIVTPGTPKTPPPPTPTDSMEWLIAEDFSLLQTVRNVLELPPNLLVVNLAQTPNWDFGAEAVNMVGFSQRTQKQCKWRYENVVAPREEGKLLFDPPSSSTDPTSPSSGKKKKTKTFIKIAPPSPSKAARNVKVSQLLAQDNNAQYRNIFCSKFDTIKSIANKRAPTTKPITVNPQMKSNKHAQVFAEHGINYDNPLPATVIAQARYDRIQMERKKLEMQRQQAAIAAAAATSGTVTPNLTGVPAQIISSGPVVQAAAMAAATANVPTAPKPRPQFTSITIPGTMPPIVLQGTPNANEALITRDAHVSISNMLAQQRRQDLTAQQQQQLLQLQQKQIAQVQTLSQQQAAQQQQQTGSPSPTPNVTILNAGPIGTTQSPQIVRQATPVQVHPSNQPQTQTVVLATGLAQALAASVGQPISVSSSAISTTTTQLSSTVNTTPSLPTVARHLQPTISTQPQQLQRVPTLTMQDIVSSANTQRIQAGLITTSASQMQVGGQPQQTQPTLVSLTPMLGPNNPQLATKIIQNPQGLATLIKRIQVVAATAPPTIVSSSSVTSHQQATVSLPSISTIQSGNTYSTVPIVPSTSSPVVTLSTAGTISKTTLGQPTVSMAISSPNVSAATASAVLSQPSQQRQVQAGFLLTLAFGGHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0Y5</accession>
    <name>A0A1D2N0Y5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small integral membrane protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_07781</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000312">
        <property type="protein sequence ID" value="ODM98898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0Y5"/>
    <dbReference type="STRING" id="48709.A0A1D2N0Y5"/>
    <dbReference type="OMA" id="ACTDTEC"/>
    <dbReference type="OrthoDB" id="10054061at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020309">
        <property type="entry name" value="Smim-14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31019">
        <property type="entry name" value="SMALL INTEGRAL MEMBRANE PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31019:SF1">
        <property type="entry name" value="SMALL INTEGRAL MEMBRANE PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11027">
        <property type="entry name" value="DUF2615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="101" mass="11252" checksum="69572B7EB6B1E24C" modified="2016-11-30" version="1">MDGGGDGGFDPCECVWSHELATRRLINMIQQRQDYCAENECYTELPGGPNSEPSTALFFMGFWFLMALVLFFLRPKATVPQDKSQDQTGPNYDPPAPPAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N121</accession>
    <name>A0A1D2N121_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD repeat domain phosphoinositide-interacting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07716</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000306">
        <property type="protein sequence ID" value="ODM98983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N121"/>
    <dbReference type="STRING" id="48709.A0A1D2N121"/>
    <dbReference type="OMA" id="CAPSINN"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM98983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="257" mass="28361" checksum="FD3A5F9C9CF15E04" modified="2016-11-30" version="1">MKLQLNVFSNFQRLVVCLEEMLYIHNIRDMKILHTIRDTPQNPKGLLALSVNADNSYLAYPGSASTGQVQVFDAFNLQAKIVIHAHASPLAALAFNMSGSLLATASQKGTVIRVFNTNSGNRLYEFRRGMKRCASIYSIAFSSDDAFLAVSSNTETVHVFRLEAPAEVKEETPTPTASWMEWVKSSLPSQVTEVWAQGRAFATITTPFHDVRSVVAVTTVPGSEEGKVRVLVASYDGFLYIYGLNPRRRRVSAPEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N123</accession>
    <name>A0A1D2N123_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CDK-activating kinase assembly factor MAT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07687</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000305">
        <property type="protein sequence ID" value="ODM98996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N123"/>
    <dbReference type="STRING" id="48709.A0A1D2N123"/>
    <dbReference type="OMA" id="HIMEAYQ"/>
    <dbReference type="OrthoDB" id="5963at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061575">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004575">
        <property type="entry name" value="MAT1/Tfb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057657">
        <property type="entry name" value="MAT1_CAK-anch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00570">
        <property type="entry name" value="cdk7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25811">
        <property type="entry name" value="CAK-anch_MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17121">
        <property type="entry name" value="zf-C3HC4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="MAT1 centre" evidence="7">
        <location>
            <begin position="70"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="MAT1 C-terminal CAK anchor" evidence="9">
        <location>
            <begin position="285"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM98996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="368" mass="41534" checksum="245926B7F275DD9A" modified="2016-11-30" version="1">MGFIQLRLDSVTMDDNLACPRCKTTKYRNPSLKLLVNTCGHALCDNCYLFWRVSGLWDPTPSLRLPSPTLEDPAVEKEVDIRRRVLRDYSKQEADFPSLREYNDYLEQVETIIFNLANNIDIIETNKLIEQYKKENKEQITKSRTRKPTQILLLEAIIEEENRRSELRHMESLHSAKEEKIRKQKNHEALIDDLMFLESDAKAIVESHKATQAHQQVEASEIKPLPSQLGISSLSSSAPQPAYQQATTFTSGIGFGGSASFLPLPKGLGEVPLFVYKAFLLEIGGPPPPSLEQLKYPSSGKEGHLQHIRPATEAEIAGGYHHAIACRRALQDAFMDIAMQPKLLKSRSIQNESESESTTKEEVEMDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1H7</accession>
    <name>A0A1D2N1H7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_07922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000326">
        <property type="protein sequence ID" value="ODM98755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1H7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="664" mass="74340" checksum="6C34C8547D5792A3" modified="2016-11-30" version="1">MGNNKQHQATKGGRVKKQSSTVLSIKRKKMIMKFKSTWITGHLEDTKEVLETKMRTQGWKEMLFENLSVEDANIRYNDVDRWIKKHHWITVPDAVPTGFTINDVQNSGVTVYSNFHSGSQQPEQHYRRNMPLLQRKPPVPPTSYSDLVAEENDEDNDDEDNDQSFHTPSAYAANTFVETADEDHNENVASVFDSSDDEEEHAIDLRIDHANNPLSTPVSRKREILDRFLGITSNQIEVDDNNASTSSAYVNPTAVNTQQDDFRFSQPDEITSARAPMGNASQGTFQEDLTTENNTEELQRVFFSQDDNYSQCQQTDQIPGTSASAYGEVRPPMGNTSHDTFQQGVTTGSNTEGEQRVYFSHDHNYSQYQQPGQMPRPPVLAPMPSLRITPRVHFEGLIRPRPKLVRAPTPSRQGPRIPHGMKNQRNPAPSSAPNSDMTNTSSSQPPYGQQDGRGIDEPSTLPPFNETFRPTSLFHTATHGIWLNPLNRVSRRQPPLYNEVLNRRYLQAQRLRQQAPGFTMSSEQTGSGPPGFCPGGLEQNTTNYQGQAFAGLRFKVIRTIVDFSDPKFKVHLIPSEKAAKATLVVEAMTAVCKKIPALRPAVDYLQSLIGPMRRAWKNELLPLKYNNAQSTIISDMKHETTQGAVANTTTSNSVQVEGTGGGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2H0</accession>
    <name>A0A1D2N2H0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquilin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_07580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000299">
        <property type="protein sequence ID" value="ODM99105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2H0"/>
    <dbReference type="STRING" id="48709.A0A1D2N2H0"/>
    <dbReference type="OMA" id="EVRFQTQ"/>
    <dbReference type="OrthoDB" id="9450922at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14399">
        <property type="entry name" value="UBA_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000001">
        <property type="entry name" value="Ubiquilin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000095">
        <property type="entry name" value="Ubiquilin 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000077">
        <property type="entry name" value="Ubiquilin like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="4">
        <location>
            <begin position="20"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="576"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00074668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM99105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="627" mass="66040" checksum="A44A0D5E34437418" modified="2016-11-30" version="1">MAEQNDNSAGADSTSMKELMNITVKTPKEQHVIEISTTASVSEFRTKVAAKFNQAEEQLCLIFAGKIMKDAETLLHHKLADGYVVHLVIKSSARGPQDPSSSTSSATPNATAPSANTTNNASSNQSTPTAPNPGNLFGAFGLPSLGALSGGGLGGNMQNLHDRVQQELMTNPDMLRQVLDSPIVQSMMNSPEIIRTMLSANPQIQQLMERNPELTHVLNNPEILRQSMELARNPAAFQELMRTQDRALSNLESIPGGYNALQRMYRDIQEPMLNAVQERLAGNPFAGLVDSTTERNPQQGVENRNPLPNPWAPQSPNSPASATGNAPGSGSGGGGNAATTPTGGGGTAGTGGGSNNLLQFMMQNNSGMQNLLSTPYTQNLLDSLIGNPDLAQQLMGANPLFAGNPQMQEHLREMTPRLLNQLRDPEFQQVLSNPAALQAIMQIQQGIEQLRVAAPNFARNLGFGAPLVPPTAPSATTPASAATPAATATTPASDTQRSENNATPATGVASPNVTSSTGNAATPTAPNPFANLGNLNRDTLNQFMSTMISSLAQQSDVAGGAGLAGLLNNSQGPQVPPEERYSTQLEQLSGMGFVNREANLQALIATFGDINAAVERLLGSNQNFPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2H8</accession>
    <name>A0A1D2N2H8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein msta, isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_07550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000298">
        <property type="protein sequence ID" value="ODM99115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2H8"/>
    <dbReference type="STRING" id="48709.A0A1D2N2H8"/>
    <dbReference type="OMA" id="ICIAYRI"/>
    <dbReference type="OrthoDB" id="5952526at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="34"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="71"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM99115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="577" mass="65844" checksum="E75384376818A89A" modified="2016-11-30" version="1">MEATVDVQESSNKSQTQATAKETKEESNKDQQNCAVCSSIATKCCTGCREIHYCSQEHQKQDWKVHKKQCSPFILKTSPEFGRHFVAARKLKGTTLILEELPVFCAPRGMIDDFETPLCLSCCIVMNVESEGARKCSKCGWPVCSLTCEKNDYHSKNECELFSKSKLSFYPTGYSVYEVYKVVEIIRGLLIKEKQPETWKKILDLQYQTELGSKTIFDDLKSVREAFKLEDLGTDDEWHRILGIMNVNNFTMAGQRATTSISYEAFLYLKTSMFAHSCAPNCWWCVTIFPEFKITVYAAEDIEKGEIITVPYTYLYSSFGTHMRMELLKGNGDYICKCRRCVTKTELGSYTSALKCLNCESGFLLPENPTDSNSEWKCGEEKCETVLESKLFDVRIEDLITKLEECDTVPALEKYIEDNKGVTLHANHWLITEAMDTICKGEPRNTSSAVEALAEKDKLIQYCEHILKVKNIVAPGISLERARLINLLARLRYERLDILTSNKLETNDEKIEEEAHFILVLYDEALKFYINDRTQTPTKKIGLKASIIMSDMVYIKTKYVPSDDTSSEKGNPDEKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2Z4</accession>
    <name>A0A1D2N2Z4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sorting nexin-27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07258</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Early endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000282">
        <property type="protein sequence ID" value="ODM99424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2Z4"/>
    <dbReference type="STRING" id="48709.A0A1D2N2Z4"/>
    <dbReference type="OMA" id="PNEFPHN"/>
    <dbReference type="OrthoDB" id="10036828at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13338">
        <property type="entry name" value="FERM-like_C_SNX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01777">
        <property type="entry name" value="FERM_F1_SNX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23070">
        <property type="entry name" value="PDZ_SNX27-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06886">
        <property type="entry name" value="PX_SNX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000210">
        <property type="entry name" value="Putative Sorting nexin-27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000061">
        <property type="entry name" value="sorting nexin-27 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000003">
        <property type="entry name" value="sorting nexin-27 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037827">
        <property type="entry name" value="SNX27_FERM-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037833">
        <property type="entry name" value="SNX27_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037835">
        <property type="entry name" value="SNX27_RA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12431">
        <property type="entry name" value="SORTING NEXIN 17 AND 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12431:SF19">
        <property type="entry name" value="SORTING NEXIN-27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="8">
        <location>
            <begin position="109"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="9">
        <location>
            <begin position="249"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="508"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="536" mass="61048" checksum="CF97B514AD1B7CAC" modified="2016-11-30" version="1">MSDDATNGATNPNPWSPRVVTIYKSETGFGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLEGGAAEAAGIRKGDRILEVNGVNVEGATHRQVVDLIKSGGDVLTLTVISVSPQEAERLEPNEETTNFPSYDYSEKRSLPISIPDYQYKYNEKTGERYVTYNIYMAGRHLCSRRYKEFSNLHTNLKKEFVGFNFPKLPSKWPFALNDQQLDSRRRGLEQYLEKVCAVRVIAESDIMQEFLTDDEQGSTTKVDLKILLPDREVVSVNVPKNANADDVYRALVMKSHLSPEASKYFYLFEIVEYNFERKLAPNEFPHNLYIQNYSTATSTCICIRKWLFTISREVSLANDEQITTYFFWQAVDDVNRGHIKAADRLYQLKALQDASRKHEYLKLARQLEGYGSIVFPHCPCDSRKEGHVIAIISAANFELQACKEDGTLESQIIQFSWSSIIQWDVDDEGMAFAFQYQRPDKPARWVKIFTTYFHFMNDCFERLKEEVICGKKDNHHHNLHSNSNNATGKGSHAQAEDELASTTPSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N327</accession>
    <name>A0A1D2N327_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-soluble NSF attachment protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-ethylmaleimide-sensitive factor attachment protein gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_07008</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000263">
        <property type="protein sequence ID" value="ODM99683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N327"/>
    <dbReference type="STRING" id="48709.A0A1D2N327"/>
    <dbReference type="OMA" id="ANRACCL"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000477">
        <property type="entry name" value="gamma-soluble NSF attachment protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF2">
        <property type="entry name" value="GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="281"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM99683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="317" mass="35392" checksum="59F7728AC537CF49" modified="2016-11-30" version="1">MAAANAKKIEEAQEHIKNAEKCLKTTLLKWKADYDIAADAYNKAAACYKSTKSYQECKDCLLKAADCYKKNNSLFSAARCYDQAGLVCKELGQLEEIATFAERACIMYQQHGSPDAGALCLDRAAKMIETQFPERAVDLYKRGVDVVMIEDRPRQASEFCAKFSRLLVRLKMYDEAADAIRREISLNQQSENIPAIGRLVVALVLVQLAREDYVAAEKAFKEWGNNCEVEEIVAMETLLRGYDEEDAEVARKALHSPFIRHMDVEYAKLARDLKLPQGIVAPSKPQVRENAAPSYKSVADAAQQDDDDGESQQGGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N344</accession>
    <name>A0A1D2N344_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_07209</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01000279">
        <property type="protein sequence ID" value="ODM99474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N344"/>
    <dbReference type="STRING" id="48709.A0A1D2N344"/>
    <dbReference type="OMA" id="QMGCTAE"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034458">
        <property type="term" value="F:3'-5' RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="33"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="512"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="476"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM99474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="537" mass="60867" checksum="263EC2999A6C557E" modified="2016-11-30" version="1">MDATKFATFFGNVPSFTIPGRTFPVELFFSKNAVEDYVDAAVKQALQIHLHPNPGDILVFMPGQEDIEVTCEVLAERLGQLDEAPPLAILPIYSQLPSDLQAKIFQKAPDGIRKCVVATNIAETSLTVDGIMFVVDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGSCFRLYTERQYKDELLVTTVPEIQRTNLSNVVLLLKSLGVQDLLQFHFMDPPPQDNMLNSMYQLWTLGALDNTGRLTDLGRAMVEFPLDPALSKMLIASVDMGCSADILIIVSMLSVPAIFYRPKGREEDADAVREKFQVPESDHLTYLNVYNQWKTNNYSSSWCDQHFIHVKAMRKVREVRSQLKDIMDSQKMQIVSSGTDWDIIRKCICSAYFHQAARLKGIGEYVNCRTGMPCHLHPTSALFGMGYTPDYVVYHELIMTHKEYMQCVTAVDGHWLAELGPMFFSVKETGRSRMDKKREAIEQQRDMDAEMKIAEEEMKAEKERELLMEKQKAKKFDIVTPGRNEPNTPRRMPSRFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N3S4</accession>
    <name>A0A1D2N3S4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_06779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000247">
        <property type="protein sequence ID" value="ODM99912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N3S4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="77" mass="9013" checksum="B5D4242DB61757FF" modified="2016-11-30" version="1">MRIPCRLRICALHTTRDLVEDPMNSNHTRPTVVNNCKKKFVHMEYGSKKPTAIYMSRCRKIPRTSSTFNMVSKYPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N458</accession>
    <name>A0A1D2N458_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coiled-coil domain-containing protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_06619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000236">
        <property type="protein sequence ID" value="ODN00068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N458"/>
    <dbReference type="STRING" id="48709.A0A1D2N458"/>
    <dbReference type="OMA" id="KPHNETT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="191" mass="21483" checksum="1A02A6FF76E324A4" modified="2016-11-30" version="1">MVVYTGPAQNMSEEIIPNFSVTDDLLSSKDKSDEVDDEPVGHLEEESKRRKDRLKALRQKLLGEQEEVGTKKIDAPLPKPVFRSYNPQDGDLQNAAMPKAAPIDIESHVADSLEQSSVTKLVEDVDLTNLAPRKPDWDLKRDVAPKLARLERRTQKAIAELILERLKNSQDLAVSVELSSDPRMRTVDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6E9</accession>
    <name>A0A1D2N6E9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endocuticle structural glycoprotein SgAbd-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05853</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000185">
        <property type="protein sequence ID" value="ODN00824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6E9"/>
    <dbReference type="OMA" id="PKAKICA"/>
    <dbReference type="OrthoDB" id="6597363at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905109" description="Endocuticle structural glycoprotein SgAbd-2" evidence="4">
        <location>
            <begin position="17"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="148"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN00824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="39173" checksum="B6158F7D25D37CF9" modified="2016-11-30" version="1">MKTLTLVIAFAALAAAQKPLKGGKHKPAYIATSPGSGLHGGESSPYQASAPQHAPQSHHGSYGGGGSPSYSSGIGKTSAKATYPLLLSDTRTLNTDGTINFNYQADNGLHQGETVDKDGTRRGFYSYPGADGKLITVKYTAGKNGFVAEGDHLPTQPQSAPYSPKQDSNDNYSPQQGSHGGHHGGQSSGFGGGGGGYSSHSPAPQHHSGAYRPSHHGGHSGGGSALGIGAGSGGNHFSHSSGGGGGGGHRGGNLPSFPQFTNHYEATFGGLGGSSGFGGGSGGGGGASPSYSGHQGGGGGGGGGSPSYSGHQGAPAGGHAHHGGASLSGHGGSSSFLQGLGSSGHGGGSIPDISSLGSSYSGPMFTASNPYQPHTTGPVNAGFDLGNGGQFTINFAPGVGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6W1</accession>
    <name>A0A1D2N6W1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Vesicle-trafficking protein SEC22b-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_05683</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Golgi apparatus</location>
            <location evidence="13">cis-Golgi network membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Melanosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000177">
        <property type="protein sequence ID" value="ODN00998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6W1"/>
    <dbReference type="STRING" id="48709.A0A1D2N6W1"/>
    <dbReference type="OMA" id="RKMAFAY"/>
    <dbReference type="OrthoDB" id="1719357at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044565">
        <property type="entry name" value="Sec22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45837">
        <property type="entry name" value="VESICLE-TRAFFICKING PROTEIN SEC22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Longin" evidence="15">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="16">
        <location>
            <begin position="134"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN00998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="186" mass="22000" checksum="F5FF23AC88350D21" modified="2016-11-30" version="1">MVLFTMISRLRDSLPLAASMQNDEEYERSLVEYQQQAKMLLRRLNQQSPRQCSIESGNYLFHYLIDNDVVYLTLCDKNFSKRLSFSYLEDLAQEFTAQNGKKIQSVSRPYFFIEFDTYIQKARKNVMDSRSRRNLSSLNTELQDVQRIMVQNIDDVINRGAVLADMDLKLKIYQCFPKSIRKMQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7B9</accession>
    <name>A0A1D2N7B9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Beta-1,4-glucuronyltransferase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">I-beta-1,3-N-acetylglucosaminyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Poly-N-acetyllactosamine extension enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">Ocin01_05502</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>3-O-[beta-D-Xyl-(1-&gt;4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1-&gt;3)-beta-D-GlcNAc-(1-&gt;4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-glucuronate = 3-O-[beta-D-GlcA-(1-&gt;3)-beta-D-Xyl-(1-&gt;4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1-&gt;3)-beta-D-GlcNAc-(1-&gt;4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46860"/>
            <dbReference type="Rhea" id="RHEA-COMP:15023"/>
            <dbReference type="Rhea" id="RHEA-COMP:17482"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:142405"/>
            <dbReference type="ChEBI" id="CHEBI:177336"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000168">
        <property type="protein sequence ID" value="ODN01168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7B9"/>
    <dbReference type="STRING" id="48709.A0A1D2N7B9"/>
    <dbReference type="OMA" id="NMKGKFD"/>
    <dbReference type="OrthoDB" id="6479716at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043189">
        <property type="entry name" value="B4GAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46420">
        <property type="entry name" value="BETA-1,4-GLUCURONYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46420:SF1">
        <property type="entry name" value="BETA-1,4-GLUCURONYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ODN01168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="471" mass="54522" checksum="40BD28A9BECE10B6" modified="2016-11-30" version="1">MEPIFALSLSIPVRLAFRNFPLITLILTVTLMWLMVIHQEKQGQPEFDSSSDFNTDEHRQAQDLEKDTNGFIFTSFSSESRCTLQGLLPELPFSRSRFDNKRIIRIFDYVRTGKSWENLVNQYSICLATQSSLDRIKHIPELLKTWRGPVSLAVYITNEEEWLMLNLYIRFLERCYPSFGNQVSIHLAVPSSLDQFCFKEGVLEKWEANQATIENKYQCHEVHDFMNLLISTFPITEKAKLALKEVYPQNHMRNIARKGCATDWTFSTDIDIIPSEGLAENLQEFYDSLKENRINCEKCAYVIPTFELEETQPFPKTKRELIACYESGAARQFHGKYYSTAHNATNFPLWASTNLEDGPVTLSHNVTSSQTFLYEPFYVSSDLIPPFDERFLGYGFTRNSQFQAAFYAGWNFTVLTPVFNIHPGLQTHKTVISPKKEGVGKNVRKEQTSRNYQIFKKVLKEMKLKQAEGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7H1</accession>
    <name>A0A1D2N7H1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000167">
        <property type="protein sequence ID" value="ODN01191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7H1"/>
    <dbReference type="STRING" id="48709.A0A1D2N7H1"/>
    <dbReference type="OMA" id="RENTIGC"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN01191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="506" mass="55579" checksum="C7A150D829283CC8" modified="2016-11-30" version="1" fragment="single">FKGPLNVIKDKITLSGYSAGGAMAQMLQISYSSLFSGIAVFSHSYYRCGPANGDIDDYDRYCTTLFNFTASQMWDPKMVHQDIQEYFNKSLIEDPKNLMGKRLYVYTGLRNVLFTPRTSLNILAVYEPYIGSLDNILTRVQDATQLLPSNTYGAPCTQNTEETHFIGNCGFSGVTEAMNFLLFDNYDRKEAFTTFNVSRGNVSEFNQTEFTKDLADHNMDEIGYYYIPQQCKQADKQCYLHFYFHGCFVGREFNGPAHIENSGLLELAERKGIIMIFPQAKSSPKNPIGCWDTFGVAGKYYATQQGPQVSALKRMLDKILNLQPTPSIQLLPPGPPLDVKALSSSRLSIAILPPNNSTTTSQIPVSFSNSTITQLLANNSSRLVLLITPTGAQLSVANSSTPQLPPLGNSTITQVTQLSAPTNSSRLIATVFIRRPASSSSTSSTSTTTTQLPASNSSTTPPTAVSSGKLKSLRNGRQTISNTYLPPKESSGPSLKKARLSKYYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7L2</accession>
    <name>A0A1D2N7L2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_05734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000180">
        <property type="protein sequence ID" value="ODN00946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7L2"/>
    <dbReference type="STRING" id="48709.A0A1D2N7L2"/>
    <dbReference type="OrthoDB" id="6426920at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN00946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="984" mass="104888" checksum="0538C8A95835CE52" modified="2016-11-30" version="1">MYHIFRVPGSETWWDTSLESLTPNVVYVPIKFAPNRNQYQSLGTSSSLDGSSTSNTPCLTQSRLVDAPAPSTSSWDLQNNRQTAVQLNESYKSVSSVTSGASSYLGRSTSSSLEQTHGSVRAISPTLPVAYPNAIITKSPTVEGSQDRPPRRGGDRKKKSSKNVLRETVINPQDMPGYKGTEKDIDKLLEFVEGNQAKSKKNSKDKKKEVKPKGNEKQMLSKAASLDENTLEYGSKKSDESLSRSRNSKEVEKKNATNITKSSTALSVGAMTIHTKQQQSTESTNSREEIPTGKTKSISTPLVNGTAGPLATKNGNGGGNGAKPATPNVKPSVSPKSQQSVEKPPAPEDEVAPTAKTEPSPPPIQPVVSKPSKPVSVKKTEDDKTGKLDESDGPYVLVQSKKKKEKKKSQQREAEAFVRPTADQQRRDVARARRSTAERRKSVGSVPGSENSECSDDDDSVRSLPAGECTPRERIPKPCSSSGGTPQTSYADIARMSRDESGKPPSTPITILSSASASSKTPPSSTKSTSSSSSSTSGAPAVTSDSAFPALSPPSAEKTAPINNAVWPCRPRIESETSTKEKSTPGHTTKSPDLASKEELSPLEASSLPLPAQSDISKCSSKLSTDKDSSTISKPVAEPLVSKPLDLQSNVKEVGGDEKSPQGPLRKAESTAVSTLESLRSSENCVDGLQLNNKSRKTEEKKGKSNKVSEEGVNKTASIKGMENGDISSCHQEPVVFCGGKFDSSQLPAGQNIGFEFGFGVIEALNDNVVTVDLTPSPNANPTPVELPQLVLAQVENKTASERPTRSQEQVSNPKTTENCWDKALKTDKTSKFQSSHEKQTVMSSTKSKGTSNLQGELTEAQPSSSLGQKGSQPQPNMVASATNSTPAPVPSTECKEVKQQETLSSASPANLQTEAVTGVSTVVDGKAAEMLSQGKLDVAQLFVPSTAANIPESLYLSRDFMDTYAEGLANLSRQGKVTYHRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N8A1</accession>
    <name>A0A1D2N8A1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Esterase SG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_05379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000161">
        <property type="protein sequence ID" value="ODN01305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N8A1"/>
    <dbReference type="STRING" id="48709.A0A1D2N8A1"/>
    <dbReference type="OrthoDB" id="6846267at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="120" mass="13300" checksum="96D7E1B38AEC7F2A" modified="2016-11-30" version="1">MPLPEIADDQEVSASSSIFSEVLMLEPHVDTRFGGLEGYIMRTTAGRRIYAFEGVPYAQPPLGFFRFRPSVPIEPWGGMREAKKPGPECLQLSPPKVLRVVGNEGNTNSKPADSFYNDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9Q9</accession>
    <name>A0A1D2N9Q9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Centrosomal protein CEP104 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000142">
        <property type="protein sequence ID" value="ODN01716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9Q9"/>
    <dbReference type="STRING" id="48709.A0A1D2N9Q9"/>
    <dbReference type="OMA" id="SARFCEY"/>
    <dbReference type="OrthoDB" id="66599at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048739">
        <property type="entry name" value="CEP104_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21038">
        <property type="entry name" value="CEP104_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomal protein CEP104 N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="326" mass="36989" checksum="6021A51BFCF0DD2B" modified="2016-11-30" version="1" fragment="single">EEAAFPSSELERHGPGVNGWRSAKSATFPQELILQLESRAKLGHMQLLAHQYIIPETIELYIGEFLGEQDGTGEQSSSYSNKIDLDKAHFILLGHVTMSRNDSTGFKARELKSISMECRGSLVKLLIQNNYTNKYNRNQQQVALVAINLLGEKLEDDDEMTKSASQITFEEMSQSERDRSLFSPYEDLAFTMYVDIEVQDLIRKMDHKKQEAVLDERFDYASKLKSSIEHLRKSGELLAKYQLEKQIAASREDFQRAKEKKTQMDTYRDNLYKTLRIKQLLEPNGRVPENDEPGKVLGISGMTRSVTELSLPPTTSSAASTPGINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NB18</accession>
    <name>A0A1D2NB18_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 18 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_04407</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000118">
        <property type="protein sequence ID" value="ODN02265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NB18"/>
    <dbReference type="STRING" id="48709.A0A1D2NB18"/>
    <dbReference type="OMA" id="WIQREKW"/>
    <dbReference type="OrthoDB" id="1845386at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007040">
        <property type="term" value="P:lysosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="10">
        <location>
            <begin position="14"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="636"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="11">
        <location>
            <begin position="870"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="822"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN02265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1033" mass="118029" checksum="EA818688622ECBF1" modified="2016-11-30" version="1">MAHHQQPQAKRELPIFSKSKVNFIPNSPITHLCVSSNRIAIAMLNKTILKIDPKDPEHPEEINLQKYDIDAKLSNMFLDPTGQHLILTFSPKDSLNPAEVMYIAPKDPKPKDVVALKGHIITAVAWNQDFESPFLLGTSKGAVFEGEILNGDVKNLKQVYDICKGNSTVICGLEFFFLPRSTKCYIFIATSKRLYQFKGNIPYREERPMFTGIFNSYINKTSEENFKEFGQNSPTGNWTGQAGNKLSILHSPNLPYPRAIAYLSDSGLMVFNHVSLFICNTVVGIFRLVENGNYVLSPPVTENGDEDFLNSMVPVSYPKSSEEDYNAGNSQSVCNLPRSLVVTDYHVLLLLKSSVKAVSILNEGLMYDDNYNEVQGRPLNIIKDPIRGTIWCYTERGVFRYTVNEEDRSVWKIFLDKGDFVKAREYSKHDADKLEVIHLKQADHCFANKEYEISAMYYAMTKASFEEVALKFVQIDDSHALKTFLLKKMSTLKSTDVTKITVLVMWLIEIYLNELGSLRDFGKQSTAEYNTLREQFLVFMSQPLVKLILLNIYVQDCVLKNKKAVYDLMASHGDQENLVHFTVVMKDFDEVIENNIANGLYGPALTTLQKQKDAQLYGKYIPVLLDKDPKATIDALISGGRMHNPIKLLPKFSSKLDNDTAKQITRYLEHCVNTLRFVDLPIHDYLISLYVYYYSEDSLMNYLEGQGTDVNRVRYDPKYALMLCLEKQLHYASIHLYTILGLYEEAVSLAIQVDLELAKTTASKPEDDVETRKKLWLKIAKHVVKEKNDIKQAMEFLKQCDLVKIEDILPFFPNFVTIEHFKEAICQSLQEYNQHIQTLKREMDEATKSAEVIRDEIHAVRNRCAVIRATDQCTLCENTLLIRNFYVFPCGHKFHADCLMSEIFPTLSQPRKKLLQELQAITLNQEALSTSSTGISSRDQLKSSIDDIIASECVYCGDNMIKLIDIPFIPQSDYEKVQKEWDPQKTRDGLFNLDPPRGILHRDSSHPLLCFARVVCVRGPERSYRDPMSSLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBC0</accession>
    <name>A0A1D2NBC0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 13">Adenylosuccinate lyase</fullName>
            <shortName evidence="13">ASL</shortName>
            <ecNumber evidence="7 13">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_04122</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="7 13"/>
    <dbReference type="EMBL" id="LJIJ01000106">
        <property type="protein sequence ID" value="ODN02549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBC0"/>
    <dbReference type="STRING" id="48709.A0A1D2NBC0"/>
    <dbReference type="OMA" id="VQENAMK"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03302">
        <property type="entry name" value="Adenylsuccinate_lyase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.60:FF:000001">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000005">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 13" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="14">
        <location>
            <begin position="456"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODN02549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="564" mass="63593" checksum="3A97FBEB32974539" modified="2016-11-30" version="1" fragment="single">EDYLFLSGVFNAIQAIQVIRLVTLPSFCKSRSYLYSVISFYFFSRSVHTYNPSSLPEDETADIFVMSSSTSDLVAFPGEEAARADLKEYANYRSPLSTRYASKDMLYNFSDLKKFSTWRKLWYILAKCEKELGLEITEEQLNEMRTNIFNIDFKLAAEEEKKVRHDVMAHVHTFAECAPKAAPIIHLGATSCYVGDNTDLIILRDGLEILIPKVARCIHRLSKFAKDQRAVPTLGFTHMQPAQLTTVGKRASLWLQDLLFDERNLVRAKDDLRFRGVKGTTGTQASFLQLFEGNETKVTQLDKFVTKSCGFAKAYAVTGQTYSRRVDVDVVSALAALGASSHKICTDIRLLAHMKEVEEPFESTQIGSSAMAYKRNPMRSERVCSLARHLMNLVGNAFQTSAVQWMERTLDDSANRRITLSEAFLTADAILETLQNIFEGLVVYPEIIKRHINAELPFMATENVIMAMVKKGGDRQVCHEEIRVLSQKAAGEVKQNGKDNDLVERIRASKYFEPIKDELDSLLDPSTFIGRAPSQVDEFLKEEVEPVLQKYSEDLLGGTAVLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBQ7</accession>
    <name>A0A1D2NBQ7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_04003</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBQ7"/>
    <dbReference type="STRING" id="48709.A0A1D2NBQ7"/>
    <dbReference type="OMA" id="MPEWGYL"/>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000023">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000068">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="419"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="953"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="977"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1018"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1059"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1093"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1137"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="23"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="14">
        <location>
            <begin position="266"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN02682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1197" mass="134207" checksum="3E8A3962CD145ECB" modified="2016-11-30" version="1">MSAYTRLSQGDGSYTQEIGDGATVKGYRTNGLKLTCFWIISTLFCGIPYLVARWLVEWRLKLTCVPSDLRSSDIVVITEEGGDATVCDVKVESISFLPDEFATSRNGVQRQNSRTRLCDAENGDSVIKYFEFQHEKYIWDDKKDAFRKIEGLVDINCQQIVDEFRGLGAHRRTQLRQIYGFNEIYVEVKGYLKLLVDEVLNPFYIFQVFSIILWSADEYYYYGACVVFISAGSIVITLYKTREQAQTLQEMAMKGTDLLVCIRNPNNEEEEINCRDLVPGDILLIPPEGLTMPCDVVLTQGNCIVNESMLTGESIPVNKSALVSSEELFNCDIHKKHVVFCGTEVIQPRFYAGNKVSSVVVRTGFATQKGQLIRSILHPKDVAFKFYSDALKFVFLLFCMAAVGMVYCIWLYVDRGATWYIVLVRVLDIVTIVVPPALPAAMTVGTLNAQSRLKKKKIYCVSPTRINFCGKLNVVCFDKTGTLTEEGLNLLCVVGVNEVEEEDEREFLEPVYNPEQLPIASQLLRGMATCHSLTYVKGNIVGDPLDLKMFAGTGWNLEEPNTGAETSRFDLLTPSVVTSGDVQLGIIREFDFTPHLQRMSVVTNSINREMVAYCKGAPEKIRPLCKSVPDNYDKVLDSFTMKGFRVLALGFKRVERMSWHKLQKVKRDVIESDLTFVGFLIMQNSLKPATIPVIKDLNSAKIRCVMVTGDNMLTALSVARECCMIPSQDNVIIVEAFEDGTVEYKMAATHYEAIEEDEAPGASNTAIINNNGDLVRTPGDGEEEQVPLVEYQPVTATRRLSKRFSIDSNAEDTVIDMEKLIPITDVVHDVLEGSNYHFAMTGKSWTCLRENCSRTELQRILAKGAIFARMSPDCKQQLVESLQEIDYTVGMCGDGANDICALTQAHVGISLSEAEASIAAPFTSKIADISCVPKVILEGRCALATSFSIFKYMALYSMVQFASVLILYTNLTNLADLQFLWIDLVITCTVTIVMGRIQPVTTLVSKRPMASLVSFSNVFSILSQILVCVAVQFGALMMLKSQRWFVPVQPTTGDDLETLCWESTTIFSVSSFQYLIVAVIYSKGPPFRKSFYTNVEFLLSCIVLTGCTAFLLVYPIGFVGRWFDLEMPTLETQSFRFILIMFPAINLVASFIFENFVSGSKIVKRLGKLIWKQEPKSQYKLLLNEIENDKYWPPVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBS2</accession>
    <name>A0A1D2NBS2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="14">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_04000</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">E3 ubiquitin-protein ligase that is required for specification of R7 photoreceptor cell fate in the eye by mediating the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk). E3 Ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Acts via the formation of a complex with ebi and phyl that ubiquitinates the transcription repressor ttk, a general inhibitor of photoreceptor differentiation, in a subset of photoreceptor cells in the eye, leading to the differentiation of cells into neurons. Also involved in external sensory organ development.</text>
    </comment>
    <comment type="function">
        <text evidence="14">E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of some E3 complex at least composed of sina, ebi and phyl. Interacts with eff.</text>
    </comment>
    <comment type="domain">
        <text evidence="14">The RING-type zinc finger domain is essential for ubiquitin ligase activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="14">The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the SINA (Seven in absentia) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="14"/>
    <dbReference type="EMBL" id="LJIJ01000099">
        <property type="protein sequence ID" value="ODN02697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBS2"/>
    <dbReference type="STRING" id="48709.A0A1D2NBS2"/>
    <dbReference type="OMA" id="TSIAQFC"/>
    <dbReference type="OrthoDB" id="4788989at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03829">
        <property type="entry name" value="Sina"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.210.10:FF:000002">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000041">
        <property type="entry name" value="E3 ubiquitin-protein ligase SINAT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018121">
        <property type="entry name" value="7-in-absentia-prot_TRAF-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004162">
        <property type="entry name" value="SINA-like_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049548">
        <property type="entry name" value="Sina-like_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013010">
        <property type="entry name" value="Znf_SIAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45877">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SIAH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45877:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21362">
        <property type="entry name" value="Sina_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03145">
        <property type="entry name" value="Sina_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21361">
        <property type="entry name" value="Sina_ZnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51081">
        <property type="entry name" value="ZF_SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0844">Vision</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="SIAH-type" evidence="16">
        <location>
            <begin position="138"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00062579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU201113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN02697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="339" mass="36881" checksum="32F61D926DF2E2F4" modified="2016-11-30" version="1" fragment="single">DPILDLECRGRKGESVPNSSGAIRSGFLISGLSLAVVESQRSLRLLRRKMTSALSSGAKRRGGPPTPTTPDATAMQKTELACFFECPVCFDYALPPIYQCASGHLLCADCRPKISSCPSCRGPLGNIRNLAMEKVAQTVFFPCKHSTNGCGTLLLHTEKLEHEENCEFRPYSCPCPGASCKWNGSLEHVLQHLLSCHKSITTLHGEDIVFLATDINLPGAVDWVMMQSCYGHNFMLVLEKQDRGDGQHFYAVVQLIGSRKQSEKFAYRLELNGQRRRLAWEATPRSIHDGIASAIQSSDCLSFDANTAQTFAENGNLGINVTISMVGTISDPSVPGASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCC8</accession>
    <name>A0A1D2NCC8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Viral IAP-associated factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_03739</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000092">
        <property type="protein sequence ID" value="ODN02913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCC8"/>
    <dbReference type="STRING" id="48709.A0A1D2NCC8"/>
    <dbReference type="OMA" id="FCEIRAN"/>
    <dbReference type="OrthoDB" id="45518at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02988">
        <property type="entry name" value="Phd_like_VIAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051498">
        <property type="entry name" value="Phosducin-like_chap/apop_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809:SF3">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="4">
        <location>
            <begin position="56"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN02913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="241" mass="27465" checksum="31AB499BF7A2C116" modified="2016-11-30" version="1">MQNPNEDTEWNDVLRSKGILPPKPKEAEITEDQIVKMLDTTIMERTEGSRRNLEGLSLDELDELEDEEEERILQAMKSKRLQEMKQDMAKKKFGQVLEISAQDYVQEVNKAGEGIWVILHLYKQGIPLCSLLNQHLAQLAMKFPATKFIKSVSTVCIPNYPDKNVPTIFVYYEGEMKKQFIGPIALRGMNLTLEELEFILGTTGAIPTTIKKDPRKKVKDQMMSNLGVRSKEGESSDDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCN7</accession>
    <name>A0A1D2NCN7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat and LEM domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCN7"/>
    <dbReference type="STRING" id="48709.A0A1D2NCN7"/>
    <dbReference type="OMA" id="MENCFAY"/>
    <dbReference type="OrthoDB" id="1601181at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034998">
        <property type="entry name" value="ANKLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46427">
        <property type="entry name" value="ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46427:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22945">
        <property type="entry name" value="LEM-3_GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="92"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="547" mass="61315" checksum="55ABF1C6F7555ACE" modified="2016-11-30" version="1" fragment="single">MDDAWEFKRKQVSSFFSPGPRAKSKSPAESNNNNLRRKSIRFSFVNNNESMSTSATAGDDDMCDALESFNKERVLEILRRKNIDVNRRLPNYSLSYLHLAVGFSENDPDIVEELLKHGGDPNNSEDMEDELSPMHVSIMHDFDKITAVLMKYGGDPNKVNGDGKSCYRLAVENVEEVMENCFAYFFRESRDFRKSIAVSHHQYQPSSRKQTFLHESGSDGFYTCESQLINSDCGSEHLHSIARKLFPERYEYLMTEDESCSDDSSTLEGRKKLTTIPEESGSGFSSSPGFSYFPSPSMNPAMARGITSMTAPHLQYLTDDSISITSELSCVNSTPPVTPMPTEEELQKLRQQMNQLNVPVTPHTYNVISKFNESESRLQALLTPKTGSCNFSSDLQAGNHLKTGVINSSEKFEKFLLSIFYIGKGCGKRPLQHLVEAKDKFVAMGRGPLKGGEKIDKILEIWKSGLGVIVLSVYHHSSEREANVNEACMIDAVGLVELSNLKKGSYAGTVASSWPQKTKNQLGAFLLYKCFCTFVVSEHKSFFPEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND12</accession>
    <name>A0A1D2ND12_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleosome assembly protein 1-like 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03541</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000086">
        <property type="protein sequence ID" value="ODN03140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND12"/>
    <dbReference type="STRING" id="48709.A0A1D2ND12"/>
    <dbReference type="OMA" id="AAECKQN"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1500:FF:000001">
        <property type="entry name" value="Nucleosome assembly protein 1-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="333"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="394" mass="44889" checksum="2F8ADD0F84577A52" modified="2016-11-30" version="1">MSDPEKATPAADTSAEVDEVGEEEEEGTKPNVLSLPPGLGLDAEIQDIPAEVERRIKALKKIQVEITQIESQFFSEMHELEVKYAPMYTQFFEKRREIVLGKYEPTDAECDFSLSGDDSDTGDVNELVNKLKLESEQKSGKKEEGGEKKEAATVSGVPEFWLTIFRNVGMLSDMVQEHDIPIIKHLNDIKVEMTTEPMGFQLFFDFSPNEYFTNSVLTKKYEMKCEVDPQDPFSFEGPEIIKCSGCKIDWNKGKNVTIRVVRKKQKHKQRGSIRMVSKTEEVPSFFDFFNPPEVLDDIDVDEETQIKLTSDFEVGQYIRERIVPRAVLYYTGEALEDDYDEEEEEEEEEEGDDGEEDDDDDVPHGHGQAAGGGKGRYNRKRDNSSAKQNECKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ND91</accession>
    <name>A0A1D2ND91_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Kelch-like protein diablo</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_03610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May have a role in synapse differentiation and growth.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000088">
        <property type="protein sequence ID" value="ODN03055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ND91"/>
    <dbReference type="STRING" id="48709.A0A1D2ND91"/>
    <dbReference type="OMA" id="PTNMRGM"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000001">
        <property type="entry name" value="Kelch-like family member 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017096">
        <property type="entry name" value="BTB-kelch_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632:SF3">
        <property type="entry name" value="KELCH-LIKE PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632">
        <property type="entry name" value="LD33804P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037037">
        <property type="entry name" value="Kelch-like_protein_gigaxonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="45"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN03055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="624" mass="70043" checksum="FD5968261A1121B0" modified="2016-11-30" version="1">MAFAVEAIGDFSKMSNNHTIHFESPSHTGVLLCGLNSLRTKSLLVDVTLVAGGQAFEAHRVVLASCSDYFRAMFTTEVRESRQKEITLEGVSAKGMHFLLDYAYTSRLALNLSNIQDVLSAASHVQVNTVVEACSGYLEAQLDLENCVDIVTLAETYSLHELKKRVYRFICSNLMKFSHTTDFQRLSEGQLEYILSCDFPVDCTEADVLHILLQWLEFDTARIPYAVKLLSKIQFQEIPPDILTQMWDYSILQCLTLSAQSHSVYKIIVSQMQVDQSAFLQSKKLLKSLVNSRGMELAIIKVGGFGIAGVTNEVTYFHSSIGRWKRLTTIPHVEQCNFGMAVLNNQLYVVGGCFNQCLQENIHPFGFCYSPSFCKWTTIAPMLTERCRFTLNVVQDKLYAIGGASENVEDIAEPAAAAAETESCSCEKYDPVTDSWTAISPLPSSRTQHAGAAWAHKLFVSGGLEQQDVVSSSLLCYNTLTNEWEVKSPLLTPRADHSMVVYKDKLYVCGGWCEDEATGNRFLVNTIDEYDILKERWVVVSEIPTPRYHAGITIVESKLYIVGGFHSDATFDRTTGVIEVYDLESGEWSTVERYPQDIWEHLCATLYIPRCRDDMDVIPEMPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NEI2</accession>
    <name>A0A1D2NEI2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heat shock 70 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02997</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NEI2"/>
    <dbReference type="STRING" id="48709.A0A1D2NEI2"/>
    <dbReference type="OMA" id="SWIDCNS"/>
    <dbReference type="OrthoDB" id="7752173at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000134">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000024">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="621"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="582"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN03678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="661" mass="71877" checksum="AFD6E4CF9DAC22C7" modified="2016-11-30" version="1">MQPKKAAIGIDLGTTYSCVGVFQNGKVEIIANDQGNRTTPSYVAFNDTERLVGDAAKNQVAMNPKNTIFDAKRLIGRKFDDPKIQQDIKTHWPFTVINDNGKPKLEVDFKGETKRFNPEEVSSMVLVKMREVAEAYLGHKVTDAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAALAYGLDKNVGNKGEKNVLIFDLGGGTFDVSILSIEDGIFEVKSTAGDTHLGGEDFDNRMVDHFVQEFKRKYKKDITPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLFDGIDLYSSITRARFEELCADLFRGTLEPVEKALRDANKAQIHEVVLVGGSTRIPKVQKLLQDLFNGKELNKSINPDEAVAYGAAVQAAILIGDKSSEIQDVLLVDVAPLSLGIETAGGVMTKIIERNCTIPCKQSQIFTTYSDNQPAVNIKVYEGERAMTKDNNLLGSFDLSGIPPAPRGVPQIEVTFDIDANGIMNVSAADKSTGKSEKITIKNDKGLSKEEIERMLADAEKYKKEDEMQQERIKAKNQLEAYLFGVKQAVQDAPADKLSETEKQEVLDKCNENLKWLDSNALAEKEEYEDRLKEMEKECQPIMMKMHGAGAGGAAPGGAGFPGGFPGGFPGGAAPGGFPGAGGASQPSAGPTVEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF30</accession>
    <name>A0A1D2NF30_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Acyl-CoA Delta(11) desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">Ocin01_02805</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The histidine box domains are involved in binding the catalytic metal ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000061">
        <property type="protein sequence ID" value="ODN03861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NF30"/>
    <dbReference type="STRING" id="48709.A0A1D2NF30"/>
    <dbReference type="OMA" id="IREKCGR"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="15">
        <location>
            <begin position="142"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ODN03861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="452" mass="51565" checksum="B0344BC153316AD6" modified="2016-11-30" version="1">MPPDGSTAIMGRSQTATEDSRIPHSHPDDTMDSEPAIPSTPTSESDFEKGDTSASQSSPQLSRVEAKMQSQPEKLLKSSADSTMTQRKVASSPQDEKKEGEVDIMDIPATVDIVWRNVFLFVYLHVFSAYGLYLLFTGQVLWQTVIWTALIHTCGALGITAGAHRYWAHKSYKAKLPLKLLLVFMQTVSFQNSIHEWSRDHRVHHKYSETNADPHNAKRGFFFAHMGWLMCRKHPAVKEKGKQIDMSDLEAEPLIMFQKKYYTPLVLMTSFVMPTFVAWFFLGEKFLTAWCFASQLRYCFNLHCTWLVNSAAHLWGDHPYDKAINPAENKGVAIFAFGEGWHNYHHVFPWDYKTAELGRYRYNFTAAFIDFFAWIGWAYDLKTVSDKMVRDRVRRTGDGSWRHEKESATLTEVTDSLASSMGMSHGGPWGWGDESIPLADSQMTQNLYPLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NF74</accession>
    <name>A0A1D2NF74_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcium-activated chloride channel regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_02903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000064">
        <property type="protein sequence ID" value="ODN03755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NF74"/>
    <dbReference type="OMA" id="SLMHFHW"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13361">
        <property type="entry name" value="WW DOMAIN-BINDING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13361:SF1">
        <property type="entry name" value="WW DOMAIN-BINDING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1908"/>
            <end position="1930"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="3">
        <location>
            <begin position="29"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="3">
        <location>
            <begin position="956"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1837"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="859"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="889"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1837"/>
            <end position="1894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN03755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1952" mass="213630" checksum="ADE3C3C975432CA2" modified="2016-11-30" version="1">MLSRHLKGLLFSRLYAELRRFKSSFRVFSNRMWVTTKSRFYLKSVDLLVPSHWNADSALSATTQSFQIADVRLSPNVTYPHAENPNVCGQPGNFIELPDSFFNVANSGPYGLHWKSLLHTWALYRWGVHAEHGYVGDSKFPYAQRDLHSQEWAVTGCSDEKIAGRFLDITNPDSSCESDSSLPNTCRFVPETSGQNATTSLMHFHWVESVTDFCDENNHDKYAANKQNALCDHKSIWEVIRETPDYLAVTAQRNQSAPNVVFKTVKHSATPLFYVLLDRGLVQAPIAIANKVPRALATFITNNALRPTVAAIGAYPGPDNSPLSDLVDWSEIGTNTNAFLEAIGYLRADGPRARDFSRALVAVANKIKQKNHPNGAVVLLVKYGADVANFGNYLPESEVLNAFNEGNIIFNALELNFPNHTGFSHLGNVARGTGGGYTVVDNTGEVEMNINNVLGYVRRTLLTEYTKLYRDWKILRKESMGVASTIPVPEDIKGALEIFVSSSNPNLSQSNFTVTGDNYGAPNPSQLSFTYRRTLDWNEAGSKYTYKLDVPRAQLNGSNQVNVRLACTNGACSSNVLARAEFTGETTRVKIDVLTSLENGHANLSSGQPITIYSKITKNGLPVRDAIVIATLTETNSLRVHSFRLNDDGEGSPDVQQLDGIYSAYFAPEYDGSYRLSVNVEGNPTWRSKRSTTKLEESSFIRLLPIDQGDVGCGAGNCDAEVIEGSFSQTVELTATISVVQASAYIPQPTKIFNLVPVDRPDLNQVHLYWQSPFIPGRLQSVTSYEMRSASTRADLVSNFANQTLVPLPPNFRPKQPGYPETFQIPRPTSTTYFAIRSIYRGRESTLSNVASYIVITPTDPTEPTTLRKTGSNKIHSKVPTTYTIQVRPTTPSGPTTTPSGPTTTPSGPTTTSSGPTDETTPIGETSTTAPPSDSSTTEPSSTTAAAVIRSSESSITLNENGGYNIVLAFDENLPEPTSGGGSFIVENVKTLFETFSPKLWEATKGRFYVESVDILVPSSWNVENSTDATTQSYDQASVRVSPTAERPYTENPNACGKPGQFIELPLEFLNSSEPGPYGPHWKALLNLFATYRWGVHEEHGYVGDIRFPYVYKNLSSNEWSVTGCSDQPVDGLFVDFGIETPQVCSELETLNSSSTCRFYPISTTATTSLMHFHWIESVVNFCDESNHDKLSPNPHNSKCDHKSVWEVLRETEDYKAVTSPINSTIPEVAFKVVRHNPKPVLYILLDRGKIQGSLALAQIIPRGIINFLADPRRASNVAAVSSFPGRNNDVIQRDVAWSTIGLEIDRFADVIGNLRVDGPLERDISQAIFAAVDDIKAKAHPNGAVMLVIKYGADVNNFGNYLPESDIIQALNEAGIIFNSIELGIEESGSSPVAHIAELARQTDGMYTTLMHNGVAENSVRFVTNYLHQILDEHFNDLTKNFRTVVKTTVTSGSAVNFRVPPSSANQTGTEKVQIYFSTVDGSLIKQNFTVMGASSTGGWGPLANVNFKKSQDWSVERSKWTYLLELRSSAPFAEISIQACNTCQGTYLIRTDIRSETTENVTITTFTNLDETSTDLSNNEPIIIYAKVLKSGITVVNALVDAVITDTATNSRQEVRLLDYGEDSPPDEFEQDGIYSGYFVPNRDGNFSVSVTVRGDYHVIKAKMAAILQRNSRLLPIDQLDGMECHGASCKVENLPQDFTATSELGVRIRINGTTSYIPSPTKVTSFVVFPAASQPSMLSLSWAAPTVPGRPLESASSYEIRKSTSPAALIGDFENQELVPLLPTFVPGAPGYWQTHSIPRPTVTTYYALRSSYRGTNSKISDVKAFEFVGVPEETTATSTTSGSTPDSSTSTTTSESTPTGSDTTTTSSWPTTANPSSASPPSSSSSTTPAPEEDKPFHKTGGGIALITILVVAAVAAIAAGIFYFWRKRNTDKVKINPPPETQVRASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFE2</accession>
    <name>A0A1D2NFE2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_02972</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the otopetrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000066">
        <property type="protein sequence ID" value="ODN03696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFE2"/>
    <dbReference type="STRING" id="48709.A0A1D2NFE2"/>
    <dbReference type="OrthoDB" id="6429739at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015252">
        <property type="term" value="F:proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004878">
        <property type="entry name" value="Otopetrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21522:SF62">
        <property type="entry name" value="OTOPETRIN-LIKE A, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21522">
        <property type="entry name" value="PROTON CHANNEL OTOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN03696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="156" mass="17927" checksum="D80852836E1994A4" modified="2016-11-30" version="1" fragment="single">TSLFIITSALYCKLAVIICLAFLLSEVITLNVPLYFFEVIFTYLYGGSILFFLYVFCYLLHDSSQKKRQRNKEKKDKEAKKDEEVASDAAASKSGERKQSFLQRILLQEAGWNNDKNGFLEIDYHFSLYFVGVIITTVAYGTGTEYEFQESSSKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFG3</accession>
    <name>A0A1D2NFG3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000057">
        <property type="protein sequence ID" value="ODN04010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFG3"/>
    <dbReference type="STRING" id="48709.A0A1D2NFG3"/>
    <dbReference type="OMA" id="FISLMRW"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="536"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="647" mass="74169" checksum="F4F9F72A3CFBE168" modified="2016-11-30" version="1">MFNKDANCNSNPILRIVCVEKCPDPDNGEPWSVTKAKQRGDNEETIKRVLVCKYGVDKSKFTVDQLVEPKRQLCASYILPAKTKNVSKWKWRRNPVKNVKSIIASRCIPKLANIDEFVRTEGMDKGTLQLGVDYIIQFFNAKENMEYVFEDLRASWVFILGLLVVGAIASLIWICLMRCFAGIMVWLSLLGMIVVLSFCCYFSVTRYHELKSVNDTGEFSRAANPEFFVSEEELKEQLDTYLKLQTTWLVFAIITGTLLGILLLIVLFLRSRLFIAVALIKQGARAVSDMSFTLVWPLVPWVMQVAVIGWFLLVGLYLATASEKVYNVTRNCTCNGVEFIENQRCEPERFNKTIQKCLEACQDSACAFQQFQKLQNGLWFHLYNFFGLLWLLCFVNDMGDMVLAGCFAGWYWTLNRSKNLSTFPVGSSFLRTARYHLGTLAFGSLIISIIKFIRYFLEYVDYKTRQYQDNPVAKAVMWCMKCCFWCLEKFMKFINRNAYIMVAVYGKNFCTSARDSFFLLMRNALRAFVLDKVTDFLLFMGKLVITGGVAIGSFFLFTHSIGDGVNDTIPQLNFYLIPVIIVTIGTYFIASLFFSVYDMAVDTLFLCFLEDCERNDGSAEKPYYMPKELMQVLNKKNKPPSANGKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGE8</accession>
    <name>A0A1D2NGE8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hyccin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02357</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Hyccin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000047">
        <property type="protein sequence ID" value="ODN04340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGE8"/>
    <dbReference type="STRING" id="48709.A0A1D2NGE8"/>
    <dbReference type="OMA" id="HAIYYAM"/>
    <dbReference type="OrthoDB" id="18937at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018619">
        <property type="entry name" value="Hyccin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31220:SF1">
        <property type="entry name" value="GH21176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31220">
        <property type="entry name" value="HYCCIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09790">
        <property type="entry name" value="Hyccin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="44363" checksum="5FBDA7DF4279A500" modified="2016-11-30" version="1">MTDGIVSEWLAEWNNVSQDPHSEKVSDFADSVLANEDLFQAVTHVLEENERFRPLYGDVIATLFALYRSPEKKLRLFAAQFIPSLIYVYLHQIHTQKKCIALETLLRGIYEFESSSEDGPPSGFRIPNVNLPSIYHDPGGVSTSWVSDSDLDRLNARTVKEITRPTLVLSDERIRAPQRLPLCTEVWWIFNYRLPDLPKASVPMQLKTISKLVTQGFHQAGSQSRIQPPIRVVLSSKLLIEMVHTVFFSVYNGAPTLAEQTLEEMSMRAEHQLWADAMLVCNAVRDYLKSSELPVQVEVSRFKKSIITNASFRTKKLPDDIPIVESDNATHEEPGSGETSALSAGLASFKSKSKIPHILAKMKRNSVVVITEEGDVETIASPPSSERKKSIDATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGT8</accession>
    <name>A0A1D2NGT8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cubilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_02513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000052">
        <property type="protein sequence ID" value="ODN04176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGT8"/>
    <dbReference type="STRING" id="48709.A0A1D2NGT8"/>
    <dbReference type="OMA" id="ACCHHRI"/>
    <dbReference type="OrthoDB" id="6431754at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905544" evidence="4">
        <location>
            <begin position="19"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="343"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN04176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="401" mass="45233" checksum="1ED081282043BA30" modified="2016-11-30" version="1">MLFGILMWIVISLGPLQTSPEFVVHEIEACCHHRIALKCSGDEHMKIAVVQARYVIDSEEQIPATASSSHRHYPFSASRQNETIVLPPPSSSASNNPPLSRNPRTISLWDLDIKFVHDLINENLPHPVHVNAPPWHPSHISHFEDKKRFQYRRVTIPPVFNKDGLNFTATRVIEMPPYQLKFLDKDTIWREPLFSIGESESSIMSSDSYVPNKNSGSGGGVGKRSHHQEPPTPNEQVPSTETNTESGAYDDGVGECWSYQALSSTSATFTTDSSKIKPPWHFKDLRAYFNQRCSGRSKCTVELVRGNQPDPDVTKLCHLLPEGKVTVKYLCYNSTSEDVHSRCNVDVMPANEGFLHNPGYPDLYPGDEPCQWRLHVPQQKILLVFFDISLRGQYIAFLSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHD4</accession>
    <name>A0A1D2NHD4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000039">
        <property type="protein sequence ID" value="ODN04622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHD4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="247" mass="27544" checksum="4598E8F201284418" modified="2016-11-30" version="1">MSLSYKLDKGHCLFCPTIKIKLVVVVMPAPSSMLGRHANSLNSANGNGRVDSTSQPPPRNSNGLSEVGASASAVASTTSFYDEVFASKLVSESKTLLWEIKDFESVFGQQVEKAMNFEFEVGRLGSMERHLPRRSRWKVMFDGQSDMPGFPPALRVLLLSPENKTIFYRLEACIVNGSSTEKECGDERLKLTSIHFQEGRNDCDTFDNLHSFALGRADFVSNVRRYIYEGSLFVKIVMKVLEDSSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NI64</accession>
    <name>A0A1D2NI64_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-serine ammonia-lyase</fullName>
            <ecNumber evidence="3">4.3.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">L-serine deaminase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">L-threonine dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_01734</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000032">
        <property type="protein sequence ID" value="ODN04947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NI64"/>
    <dbReference type="STRING" id="48709.A0A1D2NI64"/>
    <dbReference type="OMA" id="KCTIFLP"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF2">
        <property type="entry name" value="CATABOLIC L-SERINE_THREONINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="9">
        <location>
            <begin position="9"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN04947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="328" mass="35713" checksum="3D77574882D5CA1A" modified="2016-11-30" version="1">MGSEAKVIYARTSLMYSKPLSDIIEREVYLKLENTQPCGSFKLRGLSVLCQQKLKNGCTRLLGTSGGNAGLSLAYTAEKLNVPCDIYVPTYVPPRMLKKLRSYGANITIIGKDWQETNAAAMELLKNRPEIGFIHPYEDPLIWEGHSSMVHEIKEDLRGRKPSCIAVSVGGGGLSLGIMEGLEAVGWKDVPLLCMETVGSECFNLSLKTGTHFVLDELKSIAKTLGARSVTAALLDRVEKFNVVSKVLPDKDAVLGCVRLADDHGFLVEPSCGVTMASVYSKVLPEALESRGYRTDNGPIVLITCGGSDISHEILKDLADMFDISLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIN5</accession>
    <name>A0A1D2NIN5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transport and Golgi organization protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000030">
        <property type="protein sequence ID" value="ODN05120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIN5"/>
    <dbReference type="OMA" id="TMEEPIN"/>
    <dbReference type="OrthoDB" id="191601at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="338" mass="38122" checksum="FC6B2811DCC0B1FC" modified="2016-11-30" version="1">MCIMFMYVSNCGKKPRNSKLCKPATYKLIMASNRDEMYTRPSKSAYFWDNSDSHILAGQDLKELGTWLGISKHGKLAVLLNVNGCSPPSGLGKPSKKKQGENTSRGSLVTGFLRSPSGLAAWTYCTSLCQDPENLDIRKLYKPFHLITIDIRGRHCECDCTKTTTDASSIRVTHLTNTKSCPDERSVPRYMTPFINACQYYAFGNSVVDKPFKKVSAGRDEFKNLVSKYCGEEASKANNQSLKNELVEFLRCREQHFPDPVCNEHAQSNGIPTEILAQLSSRFVTVPQYGFGTRSQTIIIIDTDNNVRYYAFTMKEPINPEDPVWEESEFKFKLSPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NIQ5</accession>
    <name>A0A1D2NIQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Triple functional domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_01532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000029">
        <property type="protein sequence ID" value="ODN05158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NIQ5"/>
    <dbReference type="STRING" id="48709.A0A1D2NIQ5"/>
    <dbReference type="OrthoDB" id="10256089at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13241">
        <property type="entry name" value="PH2_Kalirin_Trio_p63RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051336">
        <property type="entry name" value="RhoGEF_Guanine_NuclExch_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055251">
        <property type="entry name" value="SOS1_NGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22826">
        <property type="entry name" value="RHO GUANINE EXCHANGE FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22826:SF106">
        <property type="entry name" value="TRIO, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22697">
        <property type="entry name" value="SOS1_NGEF_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="4">
        <location>
            <begin position="437"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="609"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="374"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN05158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="749" mass="81526" checksum="06A66003108AD08D" modified="2016-11-30" version="1">MGMFLGPLRKKSKGFSDDKEKRKKCKEKKNCTANKNLGENKLNWDDETVVVVVEDGGGTRTEANCNKGKEENGCMKPILRSALGNKRKKNDGSSGSGHGIFRDLVVNGEESLNVTVVGRCESWSAGTKLPGNLHSLQSGKVYQDKNKLGASSGGLIDDEHPFLDRAHSAAAVFFGSSNSKSIKSTSVSPAHSSSNCGAKTLCSSSPKTPIFANDVNRHLYTTLVGVLASKSPHSHDADSGSSSGYGSCSCSKLPPTSPTAVTSGTTSDMGNRPSGQSEEEALGAIRPSRSCSGDVGLSDHGAAPPVIPAQTGEDAEDEVELPPPMKPISQQLLEATANAKTTEESQTKREQHENVERLNELSLNEPSSTSKVLSSPDFPGPSSSGVSENCVKTGNGSVTSGDMGTIGEAGGSSLTDATGGAAESPVAENETALAIKKRTYVIRELVETEQDYVRDLREIVVGYMAIMRDPNSEIPMPEDLRGGLERCVEHPEEIGLLFSKHSRRLHMYVVYCQNKPMSEFIVSEHIDTYFEEIRLKLGHKLTLCDLLIKPVQRIMKYQLLIKDILKYTERIGNKDEIESLKKACDVMHVVPKEANDMMNVGRLQGFDGKITAQGKLLLYGPLLCSEGTSALNFKGKELQVFFFEQSIILSESVGKKTQFSNPVYIYKGHIQVNKMSLTETVDDGDPCKFILRSTDPKKPNLSFVCQTSSKESRDEWIGQLQQILQTQKDFLKAIQSPIKYQKNKLTKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLN4</accession>
    <name>A0A1D2NLN4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Ornithine aminotransferase</fullName>
            <ecNumber evidence="6 11">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_00467</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="6 11"/>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLN4"/>
    <dbReference type="STRING" id="48709.A0A1D2NLN4"/>
    <dbReference type="OMA" id="VCEGNFH"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODN06180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="439" mass="48192" checksum="ABFD13D99E61D45C" modified="2016-11-30" version="1">MFRSLRILLSSEIAQVSCIRTKASMAKPVVATSNGGGLKSHQIFDREDKYGAHNYHPLPVALCRGKGVYVWDVEGRKYYDFLSAYSAVNQGHCHPRILDALKDQAEVLTLTSRAFYSDVLGEYEEYITKLFGYDKVLPMNTGVEGGETACKLARKWGYMKKGIPADQAKIVFVEGNFWGRTLSAISTSTDPSSYEGFGPFMPGFKIIPYDDLNALEEATKDPTVCAFMVEPIQGEAGVVVPHHGYLKGVRDICTKNNVLFIADEVQTGLARTGKRLACDHENVRPDILILGKALSGGVFPVSAVLADDPVMLCIKPGEHGSTYGGNPLACKVAMAALEVMEEEKLAENAQFLGEFLRQELSKLPPQVVRLVRGKGLLNAIVINQEFDAWDLCVRLKENGLLAKPTHGDIIRLAPPLVINKQQIDEAVQIIGETMQSLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLT4</accession>
    <name>A0A1D2NLT4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000010">
        <property type="protein sequence ID" value="ODN06169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLT4"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN06169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="8872" checksum="AF33BA3219476765" modified="2016-11-30" version="1">MFFTGVNFHSKNRKKSETKPVVCSFPSVTVPLCFFEKHTCGKVSHLFETSENVERLRSDCRTLNTAHFFVSTLEGNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NM54</accession>
    <name>A0A1D2NM54_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000007">
        <property type="protein sequence ID" value="ODN06317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NM54"/>
    <dbReference type="OMA" id="FIIHWNT"/>
    <dbReference type="OrthoDB" id="8265277at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="38037" checksum="6DB5143102978BF3" modified="2016-11-30" version="1">MKPLFFQKMEFFRFGLPLGVALILSALVETTISAYEVYMDVGSVFIIHWNTPLWELLSTWTVMLLNTILFLQVIADVLCLWYGTIFKGNWIALLSWIVMTSISVLTLSVVWVHHVVSERSSGNALWSAIYTVTLYTLFYVYLMFIAIQCLPHLRDQLLEEIQPIGKGFSCLWRYFARNAAVGARLLLTAEVILNVYFFLSRKLPPVLFDRFYSGHEDDDSVPILLEEYYIRALRLVIAFVGIVFVHMDKQKWMKMWCMAYAVPLVASFIIFFYMAFQWIAEHEVLTYGFFIFFAVNISFRFIVFLVCLLYSNPHDSNPFSFVTEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMJ7</accession>
    <name>A0A1D2NMJ7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Venom metalloproteinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000005">
        <property type="protein sequence ID" value="ODN06439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMJ7"/>
    <dbReference type="STRING" id="48709.A0A1D2NMJ7"/>
    <dbReference type="OMA" id="ACANSEE"/>
    <dbReference type="OrthoDB" id="7771573at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905762" evidence="3">
        <location>
            <begin position="17"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="4">
        <location>
            <begin position="160"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="597" mass="66634" checksum="8A7557973E673A3E" modified="2016-11-30" version="1">MKKLILVFVAFACANSEEIRPEPEINVVSQLEYDVTSDLGKQYNLKLTKAEGASVLHPNIKVISVGKDNESGFLSFDSWTPSKEELRVAEDVYVDANNLAAVHIKHENGKRSMLGVVDGMKFEEKNGAATLLPPPPQNRTDYIDIGRKLTASKQGGSVNAVVEVVLVLDKEFGDIFQHDRRRILDYFTVYFWDINLRYKTLPSNSVSFRITGIIVISSPSGQPFIEEARASDGRAEFGRILERFSFWVYKQMSSFPKFDMAVAITNTRLEWGGGLAYMRAACSVDNGSRRHWGTLVFNDGGNWQSMTVGAHELAHTLGAPHDDDPGFPGGCQAKGYIMSGGNENLKWFFSTCSDRTIGEFVRSNEGACLRRIDENGSPAISSDFSSVLAPTMEEQCKRRLNNPNAFMKEEDKGNCKTLKCWVPRAEGGWLIWSLGAELDNTPCTGGRCFRGRCRKQGNLIRNVGDGRCLRATNPFEFMAPVDLVACPEPRSAGTPLDRFVLTDESIGRTLATPWSSRDASENGDKCVYTGYEEGGSMWTDRCNSQNSWHGWEFISVGNGEFMISHRNTKRCAKPNGAYIATYSNCNRNDFSMRWRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NMQ5</accession>
    <name>A0A1D2NMQ5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein LURP-one-related 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000003">
        <property type="protein sequence ID" value="ODN06531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NMQ5"/>
    <dbReference type="OMA" id="LEMKGNW"/>
    <dbReference type="OrthoDB" id="97518at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="238" mass="26867" checksum="3B3009A87399DEC5" modified="2016-11-30" version="1">MEPMDLGGSSGAHSSNQDVRNGPEEAGSKDNLLQNEYILRQLPEMICGTVQRHCTPYATTLHIRKRFFTRKVHSDIFTMKSEKCLYKCVTSADGVRDIRTIMELATGLPALNFKTNKFRFSNRFSLRLGDSYHQIGRCVVLQTLLKTKFIFDFVDVLSMDKRRIFIKIRQWSRSVLLYLGDPKEGGIPIAHLYPPGTASLRWGSFPNYGYDVDIAPGVDVALVIGLILVADDYVNVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0C7</accession>
    <name>A0A1D2M0C7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_20245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01009293">
        <property type="protein sequence ID" value="ODM59386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0C7"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM59386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="21" mass="2431" checksum="72008C2D7E941BCD" modified="2016-11-30" version="1">MKTTLHQNSMKMTKFMSFPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0R0</accession>
    <name>A0A1D2M0R0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01008612">
        <property type="protein sequence ID" value="ODM77881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0R0"/>
    <dbReference type="STRING" id="48709.A0A1D2M0R0"/>
    <dbReference type="OMA" id="IFQHANG"/>
    <dbReference type="OrthoDB" id="6590017at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47160:SF5">
        <property type="entry name" value="MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47160">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="85"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM77881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="322" mass="37238" checksum="BDE8C05D11BE4F65" modified="2016-11-30" version="1" fragment="single">TISESPQFPILSNIFNYPATLVKYQLTTKDWRTFYCLILDQVTDRILIFGTMKKSSSIWNIPLNGMRRAPFKVAPLLFDQLYTIHVSRFGKVIPTVYALLPNRYESTYVKMLNALKDLAPNLNPRSITTDFERAAKNAFKVVFPVCTQHGCLFHLGQCFWRRIQTLPEKVRKALAELISDPFYSSSTDIEDLVDYVEDNWVGGNRRGRERPPRFAIEEWNCHSRVIEDLSRTNNIVEGWHRGFQSQLGAAHPTIWKFIEAIKKQQSLNELQMEQQLAGESPQPQRGRYQDLTIRLKAVVEDFENRPISDYLTGIAHNLNLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M0Y3</accession>
    <name>A0A1D2M0Y3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_20057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007928">
        <property type="protein sequence ID" value="ODM86625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M0Y3"/>
    <dbReference type="OrthoDB" id="1740355at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="181" mass="19890" checksum="63F0A6BD1BA95EF0" modified="2016-11-30" version="1">MARTGNFKWRGSHNCHGGHWSKEETHEALNGTTLLENMDGLIPAPAAPGTTDNNGHWNPYYWNHRWEERELVWHLELNGLPVVGCASSACWQSDLLACGDFFACPTRADGSSPDCSKPQMSFPTSGEKAGGETPGTMKSLRVWHAAKDHPTFLHGNSGPSCNTGQLSADQNFIAVRIHNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M196</accession>
    <name>A0A1D2M196_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ascorbate ferrireductase (transmembrane)</fullName>
            <ecNumber evidence="11">7.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_19960</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.3" evidence="11"/>
    <dbReference type="EMBL" id="LJIJ01007492">
        <property type="protein sequence ID" value="ODM86722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M196"/>
    <dbReference type="STRING" id="48709.A0A1D2M196"/>
    <dbReference type="OrthoDB" id="7733414at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140571">
        <property type="term" value="F:transmembrane ascorbate ferrireductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF24">
        <property type="entry name" value="DOMON RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="600"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="653"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="460"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM86722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="742" mass="82950" checksum="6D682CDA6368170F" modified="2016-11-30" version="1" fragment="single">LRSPLPNSNLVPPSQAVPEVSTSIGLKMSPGHGLLLVIFLFILGILMSPREYCSSEEQDMVVDSFCVSSGYNDKFYFSLGEDYMKSGINLKGFIRTHYGVHDGTLQPLKRSMFATLYAINTGNRFLAGHLAIKILINKDNFPNAAFRLAYLQMEDENTNAVGEFLQSPPCNGSFTATKVSTLFFNPCSQANPSDNQVPIALTYLWPDKIANKDVKEAVEGELGGAKVWELLTFARFSHTSCNKPKKVRIRAYVTNDNEIRLFPDGHYAVYRSRWVHPDWVGAADIVHPHEQDSCSLVEIADSEPGDKAPTPAPPVIPWIKMVDYSKTQGQNDPSWKTKHCKPIYHSLGFDYYGKNIEDWPIAFGKVGVRNLEDLKKTPSFAGRCKERQVGGNVDESVKNSYMHDCSAGLTENDNFTKYSEYLEKRKGCFESRDCLCQCRDTLDVYALGKGRPKCRGYIPKPRAGAAPGSILFLGYETTGPAGVSILTGRKAHGIVMTIISMTFVPISIMISRYFKETWLPRAHLQIVQVWYMVHVFAAFFTICLYVFGMTAMLRSRILLGHSWVTAAIYHRLLGQVTIILFVLVAVLGPLRPTSNSPFRMIIMMAHALLGGLYYILGMITVVLSQWIPGSPSADDTTCIYFTETFMAKSTYRVLPLVAGWLIIDFLFHVLFTVLQCMLDSRAGYKRKLLIPLLSILKGGEEHSTKGSKLRTLLFIIYCVLNVGISFTLIGFMIGSKEAVKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1D0</accession>
    <name>A0A1D2M1D0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tigger transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_19905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007298">
        <property type="protein sequence ID" value="ODM86776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1D0"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="2">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM86776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="97" mass="10891" checksum="9B71846A5A715A06" modified="2016-11-30" version="1" fragment="single">NSSFFVRLISNKMSEKVKRKSFSLADKLKIIQKFEDKEGIKSQNVQFNADFKKSSEVPVSETARSRHIPVNGPLLQEKAKEFASLDGIPNFEASNGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1N2</accession>
    <name>A0A1D2M1N2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01007043">
        <property type="protein sequence ID" value="ODM86831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1N2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="225" mass="25637" checksum="9BEDD2E417792CAB" modified="2016-11-30" version="1">MSFAQNYLEISSSVAMQQLLKTRSETDAFCEKCELAVINPICKVYLELLSAQLRLSWELERLGKLLENSQSDQQEGDTNLEILVGQLGIENVEQFEEFRKLLAKKCELKRNEAIPNVLLMSRCDEGRIVPSFWDYDEDLDHSLHDPFDTQSLSENRDDDEVETKPEIVIVIKTEPETLQNFENRNTELDTDADSPTASNSVRLPQTSPTNGEVSWRKLTILPGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M1R9</accession>
    <name>A0A1D2M1R9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinaldehyde-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_19775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01006817">
        <property type="protein sequence ID" value="ODM86907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M1R9"/>
    <dbReference type="STRING" id="48709.A0A1D2M1R9"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="55"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM86907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="197" mass="22732" checksum="AAE4E838B75CB74A" modified="2016-11-30" version="1">MHPGVSTRLISPQDDSLLLIYLRGRKHRVNQAFDTLKRKAEVRFDEYPEVFPEEVPDALSNLAKRGVYGLTKTRDKFGRRIICFNTGEWNPNELPFEEFGGAATHFYDKMILDKDVINNGLIIIQNCGGMGLKHARQYTLHNMLLILNVFCLAYPIKLKGLYYVNVPSYVKYLFKIIQPFLSKKLKERMVIMGTGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M3N8</accession>
    <name>A0A1D2M3N8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450 4d1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_19116</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01005049">
        <property type="protein sequence ID" value="ODM87566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M3N8"/>
    <dbReference type="STRING" id="48709.A0A1D2M3N8"/>
    <dbReference type="OMA" id="PFLECMR"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM87566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="202" mass="22987" checksum="B9D468AE030325F1" modified="2016-11-30" version="1" fragment="single">MADYLDEGLITSNGDKWQARRKLVAPLFSYKCFYHFIDIFNRHSKDLIDELDVMFKNGEDGPKSIQNTLMGNALKIICEAAMGVDASVSSAKDFDKFFKDAIKGKEYIRRKCLSPWFKVELIWKLHPFLECMRKMSKLSKISSARLSTNHEKNLHSKKKMVVSIRVTLQNKTVMEVLLGSGLTDAGIREEAHTLISAGHETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M507</accession>
    <name>A0A1D2M507_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_18677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01004268">
        <property type="protein sequence ID" value="ODM88004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M507"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903476" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="69" mass="8021" checksum="1524E253C2FCB4F2" modified="2016-11-30" version="1">MKSLFFLIAIFVTAFISSIQCLDLESAKEQPCFKIKKTVPLITDDWVRSTRAKAIYYPLMSRLDLYRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M6S9</accession>
    <name>A0A1D2M6S9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylglycine monooxygenase</fullName>
            <ecNumber evidence="1">1.14.17.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_18050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a [peptide]-C-terminal glycine + 2 L-ascorbate + O2 = a [peptide]-C-terminal (2S)-2-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O</text>
            <dbReference type="Rhea" id="RHEA:21452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13486"/>
            <dbReference type="Rhea" id="RHEA-COMP:15321"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
            <dbReference type="ChEBI" id="CHEBI:59513"/>
            <dbReference type="ChEBI" id="CHEBI:137000"/>
            <dbReference type="ChEBI" id="CHEBI:142768"/>
            <dbReference type="EC" id="1.14.17.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
        <text evidence="7">Binds 2 Cu(2+) ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.17.3" evidence="1"/>
    <dbReference type="EMBL" id="LJIJ01003358">
        <property type="protein sequence ID" value="ODM88631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M6S9"/>
    <dbReference type="OrthoDB" id="10044505at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004504">
        <property type="term" value="F:peptidylglycine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000720">
        <property type="entry name" value="PHM/PAL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10680:SF14">
        <property type="entry name" value="PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00790">
        <property type="entry name" value="PAMONOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase C-terminal" evidence="9">
        <location>
            <begin position="149"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600720-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM88631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="269" mass="30147" checksum="230FE992382937E3" modified="2016-11-30" version="1" fragment="single">FILHNRRVTVTFGVLDLSILIPYGKPDMPDAYVCTSLELNSRYNQYIVKFKPVADMGAVHHMLLYGCTEPGLSMNKCGTAVICSEGQQRILYAWAKNAPSLILPEDVGFEIGGKSGIASLVLQLHFGDPHDMPTCGIWQTVTEQRQKKLAGVYLLATGGSVEPRATTFLESACIMKEEKTIYPFAFRTHSHSLGKVISGYRVRVDEFGECKWSLIGKKDPQLPQMFYPVEHYIPVKNGDILAARCTMESNRKRMTYIGYKATSNIYSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M702</accession>
    <name>A0A1D2M702_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003248">
        <property type="protein sequence ID" value="ODM88749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M702"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="172" mass="19044" checksum="347C9A7B40B36CD7" modified="2016-11-30" version="1">MEMCGEETQSETTSNATNTGRFVKEPEFAKVFPCFLRVFEVKDPPWFEKAFVFCSECSRQLTVVSELEEVMKEVERRLKESEKVVQDKLKGSETSSSRVEFTGGTNAIGKLGNKTNGGTQGREPEHGSSTIVSLLTYQEKQPAYVNVEVDPSVAEDLCGESEVADAESVTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M7B0</accession>
    <name>A0A1D2M7B0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_17835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01003117">
        <property type="protein sequence ID" value="ODM88848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M7B0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903553" evidence="1">
        <location>
            <begin position="18"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM88848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="150" mass="16545" checksum="0DC9A4D21A1842F5" modified="2016-11-30" version="1">MNTGTFLLIIGLALCAAVLFDNKADDRIPKGHLKFKLKNLKGMEDLFEQIKDLGLTRYEVEKVTKIAMATAKPGAIALTLDSHDPHYSFNFGGVTFKFVHGVMTPFEFMQRNGMVICNVDENTIKCRSTLDNGLFEGPTLDGQGVVNLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2M954</accession>
    <name>A0A1D2M954_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tripartite motif-containing protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_17168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002575">
        <property type="protein sequence ID" value="ODM89516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2M954"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM89516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="447" mass="52067" checksum="43C37449AF9DB5B6" modified="2016-11-30" version="1" fragment="single">MTGRVPCVEIFPLEIWECIIRNLRNSTPVLRNCRRVCHDWRNIADKVLQPRGLPWNPEFSRSTGDDEETFREQMQGTRFYRSSSIDEFIQFAGTRSLQLGPNPFPLRSIVIFPMCHEAASLYLKVPLLIAQFGEQVWHCTYYVNECFPQSILALPVIFQMPNLKSLTLLAFSWKRRGIEEELKRLDISPNAPNNLSQVNILGEHSIIPLRTLILPYYGNQLKQLYFFCEDDEEEVKMINKKGYSYKIGTNLPILERLKIFQPNTDLIQSLRDCSKLKELSLRTKHNKDVKIKLENLMGILNTLAEPLSTLHLQIEPETLGVNQAFTQMEKEVIDPSVKFPHLTSLSISYSLFINSPFFEAIISKFDNLEKLLFVDCDVDTELSGRAQVRRNEEEMSQLEFSRMCRPVWLLVPKSVNRISLRRWCRDEEDKATTYYVTCERDIVKNDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MAF1</accession>
    <name>A0A1D2MAF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic initiation factor 4A-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_16718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01002268">
        <property type="protein sequence ID" value="ODM89966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MAF1"/>
    <dbReference type="STRING" id="48709.A0A1D2MAF1"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="84"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODM89966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="477" mass="52756" checksum="4D4C4DDB5C5A1858" modified="2016-11-30" version="1">MVESKDIDIIDMAGGDADAARLKMKGFSFDEEEDFDEIIVEETGMFPEAMQVERLEDMNLKEEILDILRKSNISKPTFLQQWAIVPCISGRNVIFSTPPNCESQKAFILAITSLQLVDTENGFCQVLLLSSNYSRAIGLFKLLHPLALSLGISCHLSVGGGRGMTCKDEVSKLKAGRTHVVIGTPGRVLDMLNRDALQVSGIKAILFDEGQVLFKPLFRLSIRKILGHFDKPQIVISSTSDNDIQCSNLEFGDFIVFKVRQEQAETPCNEKEKTAKPEQALAVALTATLDPKKHFYHVISMTETRVSGVYSLFNKMGITHAAVLTKLRDGAQEVVKMFLEKGHNVFFLDSISKLKSCREILKAFLAGPSGVLVAVSSDKLFSGGFCFTLGMDPFPAIIYYDLPIRASDLHDRCCVTSNNGITVIEEKTKKQSLMKLRKFEKNCDKGILVEEFKIQQPSPPVITASNGDGIKTSPADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MBM9</accession>
    <name>A0A1D2MBM9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001983">
        <property type="protein sequence ID" value="ODM90406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MBM9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1030" mass="119140" checksum="8E9FDBFDADA323AF" modified="2016-11-30" version="1">MSEEKPEDKFGAVEAEANRNIVARPGTPVEPPGEDPIPDLIPEIWCFIFQKLSTRDQLTVLNTDPAWNEMLKSQKTNILLPLVLPHLLKYLDRNEILTCRLINPDSKEEVDKTLQTIWTSPDESFKVVSEDNFHQKKLRGQVLGISEEYRFFSTTEKLDDFKTALSLTDHAFASSYNPFLVRGMSIDIDSGSRNLATGSIYDEDLCSFQSFLSQFGHHVWRLECNLDYNYGRQILGQGIQKMFWLLKHTPNLRVLEIISDFDPEEDPVRLKKAILLQAPNKLDQLVHLDISEMNADLIATQIMQPFRKQLTTFVCKGTWFEGMEVATLKSFLPKVTNLGVAGLYSGTLKKLAKIEWPVEMLYITEGDDPPDPDEVQIEYLFRSISLLRGTLKQFELLIDLDEFEMPESLHQALFEELTYLKMFVTRGENMKVGWFWAWVQATFSHVTEIQLQIQGPVQTYMEEAKIQFGKMPKLKKIVLLSEGEDDEKMGKAVILRPRPRYETSTRSRIGIWLAIGLGELDYCASGHIKIQLKMSQKTPEDKVGGVETEVGGSDGTSPGSSCVESPFPVLVPEVWCHIFEMLPRKDLVSVLNTKMQWNELLSSKKTKILFPLVLPHVVEYLERTDFLSCRLINKASKKAVDEVLQKTWSSSEETFKVHFEENFHRDDFRVEVEEISELYDFSETEQVNDFKTALNLTNDSSQNPFILRGIISDIDCEASDPVTRSIYDDDLRSVQTFLSQFGHHIWRLDCSLNSTTTPRLLKYGVLKMYYLLMYLPNLRVLKISSDFHSGQRSDGRLTQFPELNQLVHLDVSEMNAEMMATQFMLHYREQLTTFICSGRWFETMELDTLKCFLPNLTRLRVEQLYVNTLPKLSEVDWPVEFLQIDDPDASEQVQIKLLLRTIGNFRETLTQLELYVDLEKVTPPEICATDKWIFEVLPKLKMFITNGSNMKVGWFWDWVQSTFKYTKEIHLMVTEPFAVYEERSRSNSLFEQMPELEQIVLWYDNENEALGKSIIKRPRFTAEQNLQIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MC50</accession>
    <name>A0A1D2MC50_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_16103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001902">
        <property type="protein sequence ID" value="ODM90577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MC50"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903800" evidence="1">
        <location>
            <begin position="21"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="117" mass="12931" checksum="383EF2BF7150ACB6" modified="2016-11-30" version="1">MKQVCAILFLAACVFATAFAFPAAFEDEADYLRTARQIIQGRVSRSPQMGYYGSYPVTTTIVVMAIQITLGDAWEMAMSTSIWLAITAIISNNINLILTCKWDTTTAKRITQNPISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCG7</accession>
    <name>A0A1D2MCG7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
            <ecNumber evidence="3">3.1.3.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Inositol polyphosphate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">Ocin01_16041</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83420"/>
            <dbReference type="ChEBI" id="CHEBI:83423"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:43561"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43552"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83416"/>
            <dbReference type="ChEBI" id="CHEBI:83419"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:43553"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57627"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:77144"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77155"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57895"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77156"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:20630"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:10685"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:25017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="EC" id="3.1.3.67"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:25018"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PTEN phosphatase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EC" id="3.1.3.67" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01001871">
        <property type="protein sequence ID" value="ODM90639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCG7"/>
    <dbReference type="STRING" id="48709.A0A1D2MCG7"/>
    <dbReference type="OMA" id="XHLLSER"/>
    <dbReference type="OrthoDB" id="16692at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043491">
        <property type="term" value="P:phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051896">
        <property type="term" value="P:regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14509">
        <property type="entry name" value="PTP_PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000029">
        <property type="entry name" value="Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045101">
        <property type="entry name" value="PTP_PTEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF81">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10409">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22785">
        <property type="entry name" value="Tc-R-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="22">
        <location>
            <begin position="14"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="21">
        <location>
            <begin position="103"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="C2 tensin-type" evidence="23">
        <location>
            <begin position="193"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="312"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="363"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="433"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00051341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ODM90639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="469" mass="52627" checksum="D85A26DBA6B59C7F" modified="2016-11-30" version="1">MTTVIKKMVSKNHCRMQQDGFDLDLSYILDNLIAMGYPADKLEGMYRNNIEDVSQFLELKHSAHYKIYNLCEERTYNASKFKTGIVVKYPFVDHDPPPMKIIPVFCEDVHEWLNRDANNVAAVHCKAGKGRTGLMICCYLLHSGQCKTAKEALEFYASKRTHDGNGVTIPSQQRYVGYYEYLLRASSDVKYWPRPVNLTMIRLEGNLMKHSNIVFRLTLTSPEIIYTSSSIKWKKCSGKKFSTGSTSSTSTYSHQRQPSYFNIELEDGLMLIGDVKLEIFSRPVKILRKLELCHGWFNTFFVNMESTLPLQNRQPQAQPVHSSHHRLQSCSGSSSKQDNLGSDNSSSVKAKFTKIEQEKLGKPSCTKSIDQAMTKDTSLKPVDRDSPSSSLKNSPKQHYTIIFSKDSLDKANKGKVGKAFSGDFAVHLILTDPSLTSGDSDSSTSRRHHSHNQSGGGDGGDTADLEDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MCM2</accession>
    <name>A0A1D2MCM2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001809">
        <property type="protein sequence ID" value="ODM90746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MCM2"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008903826" evidence="1">
        <location>
            <begin position="22"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM90746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="170" mass="19606" checksum="1999EE9B1143EFE9" modified="2016-11-30" version="1">MGKFLLLLGVLVIYATYLVHSEEEELYPNWQCHPGYDSSTESDEKGEGWVRWIMNKCKTEMDQFATYAPERICLKSCILQWHYITVWYGNGEYDSKLKAENEIAERLNYTFPDNTESRDKIAKSIHADCADLGSKLPVTTTCEERADFFACLEKAWSCSEEESTEKPAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ME88</accession>
    <name>A0A1D2ME88_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein msta, isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_15347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001589">
        <property type="protein sequence ID" value="ODM91338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ME88"/>
    <dbReference type="STRING" id="48709.A0A1D2ME88"/>
    <dbReference type="OMA" id="CLERNAL"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="15"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM91338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="349" mass="40380" checksum="2D0846298628929E" modified="2016-11-30" version="1">MLLDNISDFLNDCGYDLEQEIIRISGVINVNAFSTVKSEFQGRDCVRIVQCIYPWASLLAHSCVPNACWSIDNTKELRISIRAATTIKKGEIITIAYNLPETMSGTLHRLISTEDVAHFLCRCKRCSDKTELGTFASAIKCFDCENGYLLPESPTTPDSEWECCGCDSLQAVPKIVLFLNNIEETYENITRRQYSRDIEVKKLELLLRQTGDLLHENHYILQEFRMRIINLQIHSLDHVNETDLERFINHCKFMLKIADVLMPGFSKTRALLQFFLSQGLLRKVSRKTQDPEENEKEIADLYKEIHYLQTRALLYFNNQHSFSLRSEAESNQFAVCIKRQLKNLESYIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEK1</accession>
    <name>A0A1D2MEK1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bromodomain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_15369</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001595">
        <property type="protein sequence ID" value="ODM91314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEK1"/>
    <dbReference type="STRING" id="48709.A0A1D2MEK1"/>
    <dbReference type="OrthoDB" id="8063680at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="116"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM91314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="328" mass="37968" checksum="B69D1B098A0F19DE" modified="2016-11-30" version="1">MQIQAKAIESLLIKDYNRDRITGYNKTRIQDTRQPNSQPYQRGEHGGYDATTSTQVARSGAVTCDEPVAGPSRLSQLQQLFPAKGTATPSQTPSEPKTEMDKPTELPYEGSLPFVVRQKAAQTFLNPIDPVELEHSDYFDFIKHPMDLTTIRQRLRNQFYQSASECVSDFQRIVCNVHVYNGHESQAFDDAELLENIFMESLVKMPQPEVEWTRRRRRAQKASDSDASTDSDDEALSFAELRRLKQVQFLSRQRFDEKNIIFSWKILQRSCSRLVCTEDDGMVEEVYACVDRQIKLAEKQKEWLAIDTMKKFARKLRKEKDHHDSDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MEX8</accession>
    <name>A0A1D2MEX8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14-like protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_15237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001545">
        <property type="protein sequence ID" value="ODM91444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MEX8"/>
    <dbReference type="STRING" id="48709.A0A1D2MEX8"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="45"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM91444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="260" mass="30119" checksum="D6FD5A8D8289BFE4" modified="2016-11-30" version="1">MDQKLTTMGQEQIGRTLLIIGLIVIGEWSHLVQSVTTEQDLTLTAKEKRALDQSVIFLNLDFIGKPIVTANFGDWDIRKLAISGKISSLNRHIDRGFEMVTDKVRKLQESGKVVAQWDFIINMENYNLVQQGCLQCLPMYLYLVNTYENHFPAHADKIMLINTPAIFELVLNIIRPIMSPLTRQTLKVYNTNKEQWQKELFEIVDRNELHQSTVELGKFNLVQFATPTFRTTLCVYNLIFLYFLMSLLKLLIVLLVTFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGU9</accession>
    <name>A0A1D2MGU9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">La-related protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_14486</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001299">
        <property type="protein sequence ID" value="ODM92195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGU9"/>
    <dbReference type="STRING" id="48709.A0A1D2MGU9"/>
    <dbReference type="OrthoDB" id="435402at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="52"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="148"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM92195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="268" mass="29356" checksum="6EF7F0C2F28AAB8A" modified="2016-11-30" version="1" fragment="single">LPFSSSRRANVSVRDIFPHVTTLAIELLHSAEKTQQVVPCEESSSTIMVDEDKARVELQEKIVVTIEDLFSDENLAKDDFLRGHIGRHKEGFVSLKLVVAYKRVKAVSKDLPLIQAALQGRSHKLQMNVLSTKIRRLEPLPPYLEKELEKEKKKKKKESKVEKSNSAALAPPENEDGGDSPTPPGKVEGSGVAPSPPKTSQWLQKRLDAKLKSPSKMTGPLGSAPPGKALKAENSKLSQNKQVLELQRIPSQDSISFFPSAANIGGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MGX4</accession>
    <name>A0A1D2MGX4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative tyramine receptor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_14526</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001315">
        <property type="protein sequence ID" value="ODM92161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MGX4"/>
    <dbReference type="STRING" id="48709.A0A1D2MGX4"/>
    <dbReference type="OMA" id="CDIMCCT"/>
    <dbReference type="OrthoDB" id="5955450at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004989">
        <property type="term" value="F:octopamine receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000248">
        <property type="entry name" value="5-hydroxytryptamine receptor 1A-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002002">
        <property type="entry name" value="Octopmn_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF174">
        <property type="entry name" value="TYRAMINE_OCTOPAMINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00664">
        <property type="entry name" value="OCTOPAMINER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="14">
        <location>
            <begin position="58"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="239"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="364"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM92161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="514" mass="56689" checksum="AD81B3F23888737F" modified="2016-11-30" version="1">MPSTEQAHDYFDNGLWTGNSTTFAEPGCDSWGAPRHAEWEAALTATVLSLIIVLTLVGNALVIMSVFTYRPLRSAPNFFIVSLAVADMTVAILVLPLNVAYSILGRWVLGKLVCEFWVTSDVLCCTASILHLCAIAIDRYRAITDPVNYARKRTLQRVLFTIAVVWIMSFLISSPPILGWNDWPSDFNADTPCQLTRQQGYVVYSALGSFFIPLVLMTGVYVRIYIATRRRLRQRARASRLSAMARQKNAVDIGSSSRKNGGGGGGGSGEPGERDRSSISSIENNGNDGSGDHCLDRSNDDTIQLKKGRKEKKGANATSASNHRPSSSIENETAKNSTSVGSGSVKGRLHTQLTVGELDVSSKLNPANLSEDSVTDAEFQQPPKQHTSSFRDTTHSGPLTKCHGSSRGNKKSTRQPSQQVSQFVEEKQRISLSKERKAARTLGIIMGVFVVCWLPFFLMYVIIPFCKSCEEPSDKVVNFITWLGYLNSSLNPIIYTIFNMDFRKAFKKLLYIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MII5</accession>
    <name>A0A1D2MII5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001151">
        <property type="protein sequence ID" value="ODM92783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MII5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM92783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="15006" checksum="1C0DA4FF4DB42DBB" modified="2016-11-30" version="1">MSTAKEFSINSAFHAFPGIIPQIVVHQSAKMFKFVVLAACVAFAQAGLISTPGVALASGPALGAPLLGRVSVNPTEVNVVKQQVVVDHPEIRYRAVPTVVQTQPIVQTVQVAPAVRTVQVSAPAVQTVQTVRIIIMTHCSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MK04</accession>
    <name>A0A1D2MK04_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_13381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01001028">
        <property type="protein sequence ID" value="ODM93298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MK04"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM93298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="70" mass="8183" checksum="5E33A3D4D72894D9" modified="2016-11-30" version="1" fragment="single">YALSVLSKQWVLDHQSMLNLHQLRYREGAITEDDNALRSNHSSLRNFGKIILKDVEPEEFKILMDNCPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2ML07</accession>
    <name>A0A1D2ML07_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000927">
        <property type="protein sequence ID" value="ODM93729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2ML07"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="503" mass="56017" checksum="7685EDAD3AFC7A11" modified="2016-11-30" version="1">MASTFLELEAEAAQTDVESLDGTSLNNSSVTQYPASSETAFGENDFEEDLSALVESQFPPTNGDKTEKDVQGWVDKANDDGTGKLPDIPCSSSSEFQFTSEDIEKMGAALLDAIQNENYFSHGAWLQADEQEVPNGDPVHTFIDDVNKRLPLALMYLIKNIIAPPVTGFRCDATMYTEVLYHAAKAMTGPNSCPSHSAFQKNVNFKALARQASLAGGYFSELRISFRHGFSKNKLPIVRAVEEFVNDAINKAYDTENAVLFTRYTQIPEIVHDCNEKKGLRYGPDQLAKYANRLQKAVHVDMVGRSLDFLAQSGFMLKQIYIDRAGSCLSSNESALSHQFRSSSYAESYLSSQGSTSTQNDLGSPNLHEGENIDPHEMQYAQDFELDQEGFQDLSPEFRGPLQEINRGNGEYDSPGGSWNSQGSISPPQYSIPTREQQQAVDADDIDDDDNENWLMLVNAPELELINVNIAFNPANRHNDSSDDEEPARRRPRLELEENDYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MLY6</accession>
    <name>A0A1D2MLY6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_12819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000901">
        <property type="protein sequence ID" value="ODM93861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MLY6"/>
    <dbReference type="OMA" id="WDGLAVC"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM93861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="541" mass="61531" checksum="AE7C5D5E68810E69" modified="2016-11-30" version="1">MVNIQPLGRPIKIRFGAKSETTVCYHGWVSTSPYQNLRVKITTAGATPRGCCVKITAENSPGEIETECTSAKNNYRNGGSCAEDVADESPHTLKKRNATRMVRNSFGETSIVRLNPEEESYFDVIGDTGKILPKRQAEDYDADAGSSSDITPNPNLINFGEDGDGEIIGKSRVRYIDPVDEDSGPASVITPRKLGIKQPREPETYRFQLLKKTIDIFLKVVPDDAVPHSMIQTAYDIFYYLYEELDPMIHNPPGMQKKAMEFLENCLAAEPVLNFTTYGCPREIKQLVVDEYVMKKLETYYEGQPEELNNVLKSLEHVEIRKDRRYVVELYDIYVEINWKVADFSNGDGRSINLINFINKVVLNFHLRLQMIIYRFSKAKDLRYARGILGTSNLKIRMQQLDKVAAVGHSLSRYNGTYWLHRPNVDPMLMYAEDSKISSGGSDGTREESRLAFAKHLMQEDEQFSEETLQSRRSSSEVVRHLSYPFHFPEKLPPGELIWDGLAVCLHAKYSNRRSYFLDSKQWGLTPTLQELGDLFPLSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MMP9</accession>
    <name>A0A1D2MMP9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vascular endothelial growth factor receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12328</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000819">
        <property type="protein sequence ID" value="ODM94346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MMP9"/>
    <dbReference type="STRING" id="48709.A0A1D2MMP9"/>
    <dbReference type="OrthoDB" id="3256376at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000554">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000586">
        <property type="entry name" value="Receptor protein-tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF600">
        <property type="entry name" value="PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="156"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="453"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="622" mass="70929" checksum="AC01DF0C3690E30D" modified="2016-11-30" version="1">MIRLFLWIMSGSQNLVAVFLYILLFKAANQKIIKLLKVYMGASAIHILTVQATAWVYAIYFSVNLPNARYTAILIDGIFKTYLIYGAYSYIQEITEEAKMASAFRELTDYEIHEFKNGQERPTSNLDFDMKPFLDRIQYVQYKKETFEISLLELQIDKRSPLGCGAFGTVYRAVLCRNIAAQNIPVAVKTTNPTSNNVEHFKALLSELKVMTIIGNHKNIVNLIGACTEDIKKRKLYIVVELCAFGNLQNYLKSQRGTFVDLTAGDSAFIKISRYSESVPNVYAYNSHISVHLNNDDDFASTKDLAKWAKEIADGMEFLESRKVIHGDLAARNVLLTEHKVAKITDFGLSRQLYNYSVYVKTENSQLPWRWLSLEAIMDMSFSTQSDVWSYGVTLWELFQLGETPWPGYKFGLNFVKELKHGMRLKKPTYATQNIYQIMMSCWDENPKRRPTSPLGCGTFGTVYRAILCRNTEGKNIPVAVKTTNPTFSNVEHFKALLSELKIMTVIGNHKNIVNLIGACTEDIKKRIHIISINYKNNVRKYLIHISIPVNNDDDLTSTRDLKRDSGWYGLSRISGVVHGDLAARNVLLTAHKVAKITDFGLSRQLYNYSVYVKTQNVILKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MNB4</accession>
    <name>A0A1D2MNB4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Orexin receptor type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_12165</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000796">
        <property type="protein sequence ID" value="ODM94516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MNB4"/>
    <dbReference type="STRING" id="48709.A0A1D2MNB4"/>
    <dbReference type="OMA" id="ANITNCT"/>
    <dbReference type="OrthoDB" id="5987936at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF15">
        <property type="entry name" value="OPSIN RH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="66"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM94516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="162" mass="18876" checksum="A371E2E49FC4266B" modified="2016-11-30" version="1">MADYPDVTSEDLDDGNGTTNCTLYQNEYCESPEDYEDRLLSYIYPDHYEWALIVAHIVVFIMGLVGNALVCVAVFRNTSMRTVTNYFIVNLAVGDFMVILICQPPTVIWDVTNTWFLGEAMCKIVLYFQVRKKNHKNVSLLRRYRMLMELNYCHKSILCMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MP59</accession>
    <name>A0A1D2MP59_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat and protein kinase domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_12040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000776">
        <property type="protein sequence ID" value="ODM94644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MP59"/>
    <dbReference type="STRING" id="48709.A0A1D2MP59"/>
    <dbReference type="OMA" id="MHINIEI"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="143"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="178"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="211"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM94644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="373" mass="40899" checksum="36F137E5F08E63B8" modified="2016-11-30" version="1">MKSLNFWHLQSNYLVAVQNGDVDRCKALLAGGVDADQMFKINSQNIPAICIGVERGAYALVELLLRSGVAVNSRDSRGRTSLHVAIEMGYDAICQLLLQNRADPNAADNMLISPLHLAAKRGSSSQVSSLITFGADVNRKDRSGKSPLHCACTFPAANPEVVQLLVDSGAAVNDLDLSGYSPLLCALLNSKYDIVRILINHGANVDVMAGHGNTPLHITILSNHPTKWDFLDLLLKKECNMHQCNGLGQSPIHLACLKQDIDSLRILISAGANPNTVDRLGITPLGYCISNGMEKFAHLLIDGGGIEDLDKLNLTRMSAGFRKKLLQRFRNPPSLLEQSRRSLIGHLGPYYRDWANQYRDEVPKVLHPFMGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPD7</accession>
    <name>A0A1D2MPD7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_11826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000739">
        <property type="protein sequence ID" value="ODM94856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPD7"/>
    <dbReference type="OMA" id="RICEQNF"/>
    <dbReference type="OrthoDB" id="27842at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="15"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM94856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="509" mass="58203" checksum="8E2F8BC5492D8499" modified="2016-11-30" version="1">MEEEDSTEDADPTSPSTVEDLPVELLLKLFHCLDSNTINTASLVSKKWHTVIDEMVGRKLFIGRQCQFVPQDQDRYLHQYVDISKISEIGVVECFVGEVTDPNQTQTLLTYLVTRLKKVIYGDQTTEFKAPYLLKSIHFDGPIPCQYFNSMMKTLPNLMHIELHMTSFCSLQTSSLENLGWKRLKSLRIWGHRLTDGIFTTFYPADKILPNILVLLSNYFPALSSYSIEYPFDIRDEKTLTQNIFIFLKRHPYLSKFKICVNISITDDGSEFETAADREWIREAKTTSKRLNLKSLEIIISSMRKVRLAKLWMAFVEQQKSLETVTILSFRIPPLMMSTICVNNWQTLKKLFISRILMSNSNNNGRNVQIDCNDLTRCVKLTNFTCEGMLSNFTEPGLISTRSLPKSIVHLEIGGLPLLHSDAHGLFFDLPELKNICLTDVGNLGRFGVAVETIRQTIALRRIMIVTIYRSVCVFVFFSPFGGIFSILLSSRQAFVNSKKGPYDYILGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MPG1</accession>
    <name>A0A1D2MPG1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BTB/POZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000750">
        <property type="protein sequence ID" value="ODM94792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MPG1"/>
    <dbReference type="OrthoDB" id="6426401at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044714">
        <property type="entry name" value="AtSIBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672:SF1">
        <property type="entry name" value="OS08G0103600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672">
        <property type="entry name" value="OS08G0495500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="184"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM94792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="348" mass="40294" checksum="D3E5F45A2BE39A2A" modified="2016-11-30" version="1">MSVFLVKQKTFKAYDFIHANPNRPNLKRWKTSVNKVCLLQSMMAYSHNSTLLRGNVWPKLEKLLERKPSPNLTTRFREQVRISAAFLIELAKERKVEVVMTVEFQDKNWIFKFTINAKGNGVFFKRMTDKEKSEFTTAIMSGEGKLTIELIFGEAAEPTPVRPLFAQEQITSIARKMLDEQIQCDLQLISQDGTVFPCHKAFLAVHSTWFHQLFQNKPEEKVWKISMTLEGLRAFLNYVYYVDMEVPKKDLRVAVELLKVGNKYSIVPLEKDMKNLLLEFQTSAMSVEVALLLFCFARKVKGYDLLKMKAIKLMKWNLTKVSELKDLQGILGNDSDTVKELELMGLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQ78</accession>
    <name>A0A1D2MQ78_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Muscle M-line assembly protein unc-89</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">Ocin01_11621</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000717">
        <property type="protein sequence ID" value="ODM95048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2MQ78"/>
    <dbReference type="OMA" id="WLPMSIL"/>
    <dbReference type="OrthoDB" id="2570713at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030017">
        <property type="term" value="C:sarcomere"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040017">
        <property type="term" value="P:positive regulation of locomotion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060298">
        <property type="term" value="P:positive regulation of sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045989">
        <property type="term" value="P:positive regulation of striated muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000425">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000107">
        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000031">
        <property type="entry name" value="Myosin-binding protein C, slow type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055251">
        <property type="entry name" value="SOS1_NGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633:SF3">
        <property type="entry name" value="STRIATED MUSCLE PREFERENTIALLY EXPRESSED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22697">
        <property type="entry name" value="SOS1_NGEF_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DH" evidence="8">
        <location>
            <begin position="717"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1245"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1553"/>
            <end position="1642"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1647"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="2179"/>
            <end position="2269"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="2569"/>
            <end position="2643"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="2649"/>
            <end position="2739"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="2766"/>
            <end position="2864"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="3073"/>
            <end position="3327"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="3501"/>
            <end position="3595"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="3583"/>
            <end position="3882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="549"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1073"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1496"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2361"/>
            <end position="2386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="3445"/>
            <end position="3468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1085"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1099"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1208"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="2362"/>
            <end position="2377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="3445"/>
            <end position="3464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ODM95048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="3935" mass="440945" checksum="BA73AD168C450A4D" modified="2016-11-30" version="1">MSNFCRITGSTRGLPKTNHFFPILPPISPAEAKKYKNPACRITSNYNPNHNYIPIKSYLDVTHVSKCTITRNSLFKYKHFQFIVPKMNSKSANQYFYMLDSKVLLIPDEIEMQLARGIITDIQISNHTIGFKYNYKVKEYDLEVLSELMEDNLLFKTCKYTDDIHPGKGLKCVKKRNVGKRKGSIAALTQLFSDKEKKAEMDVLKSEEKIRPDHGKIAKVKGKLDERRKSVQIAPDASMEEDLAPPPLKYLLHSGEVVEEINKENAPTVKASVQGHTVVGGKVIDGLFTPGMVAKGATDKFIPGVMVDSHFTPGQMLEVSPGNKKFIPGQVIEIQGANKFVPGQLILEDDTGTFKFVPGRVEQGEFYPGEIVETQEGLKFVCEMFDANEFELQTFELENPVLFEVEDVKTLMETANVVPIEFNECCEVIFEQAVFEKRVDERVINNAKEKLKERAIEDLLEAIEFARLLGKHAIASELEGVLQADEETRSAVLSDSSVKLLLTQLVVLKGIIGGRVAEVGEEELGKAIYKSNVVAKVLVDEGVIRGSVENSHSNGSLDRNSDGTGVPSSGTVEAEELREESADPMDRTVIKQTFSSRSVETHDGAVIEFQSHHAVTEYRSSTTAAGEMLQEASALSATKRQRLGQQKPASLDLDSIPPESVELLDTTPAKHKLSLARQMRHKSGSSVSSVGSEKKSKIILKSGEEMLADSTLTFKNERDLILYELLETEEEFVRELEFVMGCYYKEIETSVLFNKYRDLLFEDFKLIYQFHSTSLLEAIRYYSDDPKMIAKSFLRLERDFEPHVRYYQDHIKIEEVISNDLDLLEFIEDLSVSKRISDTKSLADHLKLPLQRINDYVLIFKDLLDVCARIHDDEHERDVLSRVLEFLVAIPQKLDDRKFLNSIEGIDAGVLGKLGRLLGHDWFVVTEKASPSSSEGSKNRYVFLFKQKLLITKVRRISDHRSVFILKQALHLPEYEVEQIGKGFRLWKEAREILFEASEKESGVQSWVAEISKYTKREGAEILDVNKIVILDAASSKSETSEDETIAAKGVSIVEIQDSDAFVEQFSNENVQVSKATESEKVVDTPTNKQISTDPSSAEPEKIAAKPAADKSEPHQAPKEQEKVAEPQKKGSVKKSEEQEKGKPTPEPKKGSVKKPEEKAKAENPTESQDTPKKGSKDEEPQKPVSRQNSSSEAKKPVDSKPPTGSQRVDRQKSEQEKAKMADDEGAPNPAQLLRRRSSVIMAKPAVESSLKFVEPIQSIECEPGENASFRLKVSSPSTIITWLKGNRPLEDKLADRVKIESKGAVHSLTILNVNDNDGGLYTAKVCELVGKDGDISEPVSCSAVLVVHELTPEERAQKIAERDSPQFLVKFKDTELLKHTTVNFMFLIKGNPEPEVVFKRNDKVLASEGRVSISPHGVGKYEMKIEKIEDSDQGTYTVVAKNKHGVSEVNAVVKVVDEKDVFNEGTAIKPDGEGAERKGLLKPGEEPIFTWFKDGKTFEPGETSKSSSRTRRTRLRSCSNTSSRKMLGRISCSAELTVQGGINQLLKEPSAPSITAKLTDTEVSLGGSAMLELKVTGFPKPDISWFKDKTLLEAGGRFRFLYEDDESIALIIKNVNYQDEGLYKVIAKNDLGEATTSGNLVIRQPPKFMKKMTDTEMMAGESFNMEVEVEGNPKPELKWYKDGQLIVSSERIKFTQSKDGQKYIMSIERVTLDDTGAYSVVASNAVGQMSEFWNVLATMPARFTERLPGNVVCDKGDKGFEYVVKTAGVPDPKLEVKLCGKELKYEKLDHQVYKIKVGDITELKDYDLVASATNQFAKDETVCIFNVNRPVKIVDGLKEVIVKEHGEATVGVKVDCYPKPKSVKWFIDGVEIGGKAYDTKEEAGGVYKLIVKDAYKDTGCRYDVKGLSAVSRLEFNTVQELNVTLKETTPTPKGIWYHNGQEVTADARIKISKKSTETYTLTFDCVKYEDAGEWSFKAVNDIGEVSTKTTVIVEGKPQITSPLPNSMRILETETYDLSVNILDYCEENVKIEWKSNVDTTFKPIIACKKDGNEYHSSVTFVPNRKENYFKVVATNKYGETESLCQIDWIALVPPKILTPMKDSYTIQDGDAFKFESEVEGVPKPKLVWLYNGEVINEQVNAVEGVVQKGTVGEYTLQAVNVAGEAISKTKLNLLQTNPTLSNLSENYAFKEQEDDLVLSVDITGSPIPTVTWLHNGQPIDLNDPRVSVTTTPTKSTLVVKNAAKADKGAYSAQVSNQNGTAEGKANVAITFVPEIDGKITYPDLVTKNTRFELKATVKGEPFPEVEWVHPTGKTIKETEAGVHELKVYPDGSVILAIESAQMTDGGVYKLGRGVRQELTRRNRRANRNRQPARTRPRINPPLPPQIKLIEGHPLTLRTTVKAHPIPELALKFEDATLPYEQRTIENGLEFEHKCEKVATSGTFSLKATNSEGATESECRLIVIPRLKEGALKAPEFANELLDKVVNEGDELLIIAKVDGNPIPEVEIIVNGKQIDVRDILEFDGNNLKYRIPDTRMGDAGEYKIVLKSSEGQAESKCNVKVNKVFKAPEFLQKFTDQAQVPTRDCKFGAKVSGFPIPSVKWLKDGNEIDTSRSDKYKLKHEDETVLLQVRNCDDSDIGAAGCPRTEAPYFLKTIGSTEVYPGMQSKFTACVGGNPEPDFEWFKDGNRMHEAQGSRIQFVRDGIGAGLIKLIINDTNIGDIGEYKLRIFNDLGQASCAALLKFDTPGAVPLGRLLHWYSDLRPTALPDRPVITRMDEGSVTLSWKSAIPNVHSQHPCTYTLEISPADGNDWKPVYTGLQNNYADVAFPSPSLDYKFRVRVQWGERYVSEPSPYVITNSTRTPPVPEQRAETQYGIRNTPASVQFAVYGYPKPTLSFRFNGAPVTLNHTYTDNGIVTIYLNEMNEQKIGCYECIATNSHGISTQPIELRLTDIPRFLEHLKETHVCARKNGRIHCVVTGIPCPTIRLYKDWNATPRPFQQVQIDENTVSVTVLFEDTLLRDEGMYSIVATNHAGSTHSSALVRIHEDETSYNWNSYGVRPRVLRLRKTDPDEFYHFGNLIGRGTQGTHYHVVETRTGTAWAAKRMLIDESNSLHRHMIETEIENWACVNSPHVVRLYDGFFDNRTFTLINELCTGGDLFGYLIYELEDFDENTVKGFVEQILKGVRDLHETKLWHCSLQPLDILLTHKKSRYIKLTDLGVSRFNDPQPNRYSHPEFASPELISQSGINWKTDMWSVGVIAYILLTGHHPYVGLNDQETMENLKNWNGQINETHLSRLSSNAIDFLRCLLRITANERPSACEALEHAWFRTSESRMVNLFNESHVKYYTHLRAWQSNADSIDRFRRNPLEVAYKHVSKMVYPPGYDWVEEREVRVITKSDYSFPRPYVEIDDFVSESHYQSGDDTYLLQLRDTDFPARLRQYMKVAANASPRSRSTSRTATSTGTSLPPERRARGLRHEVGSRMDIQAEAEAIISMKREGREPCFRERPRSISYAEAYDQDLSLNVVVDGDPGAPDVQWFRGDTLLVADDPVHRRRLEVTTTVDNTLVRTELLIRKVKNTDLTVYKCTARNKQGQITWKFRVALLPDSLRLPSPNPALSYSLEKTPTPLSTEVHSFESVSTPEVVVKGCFTSVLKSGPRVYKLSTNEEYDIARKLIHTHVLGGEYTQAIQIGSGVACSYNTSVVGLLDHLVGLGSYTEQTVVSVVEQILHGLSYLHWCGVAGVGLGACSYGVDKQGVVKILDLSAAQKINKIGVASEAIGKRTNVQANLEFISPEALSSTDTQVCPQSDIWSVGVLIYVLLSGASPFRGENEDETKQNILFVRFRFEHLYKDLSQEVTRLIMLIFKRSPMKRPSAEECFEHRWFHPTESLTKKRQKVVFPVDKLQAYAESVALDEELSSTAAESNGVLQAFYTAHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQW8</accession>
    <name>A0A1D2MQW8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Huntingtin-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11238</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLA2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000671">
        <property type="protein sequence ID" value="ODM95443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQW8"/>
    <dbReference type="STRING" id="48709.A0A1D2MQW8"/>
    <dbReference type="OMA" id="FQMSVEM"/>
    <dbReference type="OrthoDB" id="8178130at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043325">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17006">
        <property type="entry name" value="ANTH_N_HIP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1410.10:FF:000006">
        <property type="entry name" value="Huntingtin interacting protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000012">
        <property type="entry name" value="Huntingtin interacting protein 1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035964">
        <property type="entry name" value="I/LWEQ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002558">
        <property type="entry name" value="ILWEQ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030224">
        <property type="entry name" value="Sla2_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407:SF15">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01608">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00307">
        <property type="entry name" value="ILWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109885">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50945">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="6">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="I/LWEQ" evidence="7">
        <location>
            <begin position="745"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="321"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="451"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="754"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="989" mass="112004" checksum="B26BC1BD0D451E0C" modified="2016-11-30" version="1">MSRATCLSKAINSNESPVKEKHIRSAIIGTYQERGASTFWDCVFRLPLKENPVVCWKFCFVLHKVLREGHTNVLKDSQRYRLMIQEHGRFWGHLKPGYGTLVKLYCDLLNIKLNFHIRNQRIPGNLELTDDELIQCTGDNEDAFFQLSVEMFDYLDAIIDMQHEIFKTMETSRSNSMMYSGQCRLTPLIPCIQDSMVLYDYTTKILFRLHATRTNQMFCLELSPDLLEGHRQRFLKVFAGLKQLYEKTMSLQYFKNLIEIQQLPKNPPNFLLQADLENYETRKVTVYNSMDDTQSEAHSDSFSDLVDLQESNGSNSPDPAAMARERRIKELEEEIERLKQQLERIREEAKVRIHQMRFEIQELTAQLAEKSSLLAERDKKIDELSKHECKIPNDFALRVDTAEKNAKINEDKFGKMKALYTNLREEHIDLLRKKGGCDKELTELRKVVEGQTEMGALVEDLRKEKEELESTLLKQLKVKESECEQMQTTLVELKTQIETVEATKSDLEKGLTSEMEQLKEEMKGLLGLKSKLETSKQELGAQLEDVTKKFHDISKELLNAKTANEAYEAQIGGLQSQMNENMRNMESESIRRYNELLNACIEQSQFIIRKNIEDLEHPLLTGGSGALDTFVMSCHETDKFIRDLEAATGKGYDSFVGLKSVLEQVPLFTNHVCNLLIHAGATSQTSADIQKGDEMLSDCRNLGGSVLTLYSSIKQRLPDNSLNSSYDEVREKLATLLATARGLGTTFSGKTDAADVLENELQAMEQAIDEASKRMEEILSNSRASHTGVKLEVNEKLIDSCTTLMNAIRLLVQRAKHLQKEIVSQGKGSASVKEFYKRNHQWTEGLISAAKSVGSGAKFLLECADKTMTNPGGGFELLIASSQDIAASTIQLVVASQVRADRSSENLALLKNASTGVKTATANVVATAKDCAQLIEESDEMDVTKLSTHNAKRLELETQAEVLRLQSELEKARMKLAALRQHHYHNSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MQY4</accession>
    <name>A0A1D2MQY4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Gamma-aminobutyric acid receptor subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_11405</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ligand-gated ion channel (TC 1.A.9) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000689">
        <property type="protein sequence ID" value="ODM95288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MQY4"/>
    <dbReference type="STRING" id="48709.A0A1D2MQY4"/>
    <dbReference type="OMA" id="IKRIWVP"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022259119" evidence="11">
        <location>
            <begin position="19"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="12">
        <location>
            <begin position="27"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM95288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="417" mass="47164" checksum="0062CAD8CA7E4B82" modified="2016-11-30" version="1">MALLRNLIYLLILQAVSGQEAPKKLTEFLKKKFADYDSAMRPNHGGTPVTVTVSGYVLDISPIDEKSQDFTVSLYLRHEWKDARLEFTETEAGQDKIQLTKEYADKLWKVDTFIVNERESKGHDLLTENVFTRISTDGTVLTSSRFTIRATCKMELGWFPFDRHTCPLLLESYAHTTKDFVYQWKADSNGNIKTAVGVAPEVTSIQFNIPAVNCRKESETVGSVIYSRLAVEFFFIRSATRYVHQVYFPAILVTLLAFVTLLHETGTTKSRLQISILLEGLLIVLIALSSSNMPPVNYQTALDFYLMICLLTVLFVVAVNVAFCLVINTTTNDTNGIVRLRSVYDNNHVEDEGKEVLFDTGANLSPRTNRIFTLLVKLRLGIPLVFIVFNVIYWMVVLIGSSSFPEDFMILGKNVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MR17</accession>
    <name>A0A1D2MR17_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_11330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0538 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000683">
        <property type="protein sequence ID" value="ODM95341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MR17"/>
    <dbReference type="OrthoDB" id="937at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018794">
        <property type="entry name" value="UPF0538"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18444">
        <property type="entry name" value="UPF0538 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18444:SF9">
        <property type="entry name" value="UPF0538 PROTEIN C2ORF76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10209">
        <property type="entry name" value="DUF2340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="129" mass="14277" checksum="D9ED731995072A7D" modified="2016-11-30" version="1">MASSSNATLTIRVIRSFEHRNWKPLVIHNINLDMTFGELQALVNDKLVSSSFPPPFKKLVHYDAFKLETSPSMNNSKSSNALISLSNSTPVLELGISGPLALSSEQISHESEISYFNCSEFIEYSSSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRC9</accession>
    <name>A0A1D2MRC9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Helix-loop-helix protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_11229</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000670">
        <property type="protein sequence ID" value="ODM95451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRC9"/>
    <dbReference type="STRING" id="48709.A0A1D2MRC9"/>
    <dbReference type="OrthoDB" id="9946827at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001707">
        <property type="term" value="P:mesoderm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11390">
        <property type="entry name" value="bHLH_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000090">
        <property type="entry name" value="Salivary gland-expressed bHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040259">
        <property type="entry name" value="Mesogenin/MesP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20937">
        <property type="entry name" value="IP14615P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20937:SF3">
        <property type="entry name" value="IP14615P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="263"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM95451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="487" mass="53424" checksum="A1F47265419365CD" modified="2016-11-30" version="1">MKYPISLSATDRTSSVITKELLLPVVQDNSLVNNPKVNVIRHIVTAQASRGPEKNCTIPAKISETLQHPLFEKSDIKTESDSLKMEEMKPEKGIPIHTVVSSSSTSTLSSSSSSVIRTLESNPVNSSYEVMRNVGSSDSSSTQHNENAGPNPNATLIRAPQDEYIFTHQNLMPAPIYTTNGQQQLQHHHFQLISHGHGTQLRGSTMGAGNTGPSPHIYGRSDVLGFPSAIHIERFPNPETLTRHWRSTGQIVEQGQSVDMLPDYKKSACDRERTRMRDMNRAFDMLRQRLPYTKPPGKKLSKIESLRWAIRYIKYLQSLLDCPSSSSQVGSSAGPSTGHFVPVMYDTHHQGVVNMSPQHQQSIFGSAAAAAQTLQAASTLLPHYGHPHAYQTSYLCATDPTPSTNLCIVDQALGSNAGLDGNTSSGGDYINLQQPSSDYTIQTLSSLSSTDQSSTVHQHDGFYQVTSKILYNNISLAIVFLYNSMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRH9</accession>
    <name>A0A1D2MRH9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000662">
        <property type="protein sequence ID" value="ODM95508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRH9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="67" mass="7435" checksum="B28D3DBF20AEEC6A" modified="2016-11-30" version="1">MYCILLWVGKPGCMGHSEQTKTFSKDDKDHRVDVESYSATVTQPCSTSTCDLMLTGAGPTHLQHRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MRT8</accession>
    <name>A0A1D2MRT8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein SMG5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_11156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000658">
        <property type="protein sequence ID" value="ODM95524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MRT8"/>
    <dbReference type="STRING" id="48709.A0A1D2MRT8"/>
    <dbReference type="OrthoDB" id="5920073at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM95524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="128" mass="14482" checksum="747819A493C5887F" modified="2016-11-30" version="1" fragment="single">MGDNKNGEDESRKSVTTAKKLYGSITELSLQIDSLSSRCLEIDDLFSHDLQAKRVTLKDCCESLFNVCPKTYGSLAREKLWRTGLYDAVARARKMQKDRKWTPAQLGLVKTHLQSGIGVLQLYVMKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MS56</accession>
    <name>A0A1D2MS56_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Prolyl endopeptidase</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_10739</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of Pro-|-Xaa &gt;&gt; Ala-|-Xaa in oligopeptides.</text>
            <dbReference type="EC" id="3.4.21.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="LJIJ01000603">
        <property type="protein sequence ID" value="ODM95949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MS56"/>
    <dbReference type="OMA" id="LDPWFSH"/>
    <dbReference type="OrthoDB" id="248387at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070012">
        <property type="term" value="F:oligopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.120:FF:000001">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000005">
        <property type="entry name" value="Prolyl endopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051167">
        <property type="entry name" value="Prolyl_oligopep/macrocyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881:SF2">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904452" description="Prolyl endopeptidase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="10">
        <location>
            <begin position="27"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="9">
        <location>
            <begin position="507"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODM95949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="735" mass="83131" checksum="91E2E99DC3F03FB5" modified="2016-11-30" version="1" fragment="single">AKMSSIRILLIVALFQYSLGAQKFKYPELRRDESVVDDYYGMKVQDPYRYLEDPDSEETTKFVIEQNKLTEEYLSQNSVKESIEKKLTEVYNYPKYGVPRRYGSRYFSTMNTGLQNQDVYYVQDTLDSQPQVFFDPNTLSEDGTVHLSDFEFSDDGELVALALNSKGSDWLTIRIRNVSTGEDYSETLEDIKFSAIAWTNDNVGFFYARYPKLAAKFRSSLGTETVQYGNQKLYYHRVGTNQSDDVLVAEFEDPLLLIGYFEVTENGNYLIIFPSKGSGETMVYYAALKEPMRTGIRGKLQVLPIVDSLANDYSYVTAEGSVVYLQTNNGAPNYRVVGIDLNKPEQMYWTTLIPEHNKNTLDWAYVVNEDKLVLKYLEDVKSRVEIRSLHNGTLIQHLQIPLGAVDSFGGKKSNTEFFFRVVSFLTPGIIYRVDLTTAPYEAKVFKEVKVNGFDPSSFTVKQVFYPSKDGTLVPMFIVHKKSLKMNSNANTFIYGYGGFNINIVPTFKPDRIVFLQNFNGVYAVPNIRGGGEYGQKWHEGGRLLNKQNVFDDFQAAAEFLIRERYTTASKIAINGGSNGGLLVGACVNQRPDLYGAGIAQVGVHDLLRFQKFTIGYAWCSEYGCSDNGNKTIFDNLYRLSPLHNVRLPLNDSVQYPAVLLTTGDHDDRVVPLHSYKLIAELQYRIGRSPRQTNPLLIKIQTSAGHGAGKPTSKKIAEYAEMYAFLVESAGFVFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MSV0</accession>
    <name>A0A1D2MSV0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Nardilysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_10528</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000571">
        <property type="protein sequence ID" value="ODM96157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MSV0"/>
    <dbReference type="STRING" id="48709.A0A1D2MSV0"/>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054734">
        <property type="entry name" value="PqqF-like_C_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22456">
        <property type="entry name" value="PqqF-like_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="9">
        <location>
            <begin position="212"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="10">
        <location>
            <begin position="365"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 middle/third" evidence="11">
        <location>
            <begin position="594"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme PQQ synthesis protein F-like C-terminal lobe" evidence="12">
        <location>
            <begin position="976"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="155"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODM96157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1168" mass="134286" checksum="314ECA324ADAAAF7" modified="2016-11-30" version="1">MAKARKRTEKSNKNSSVLKGLKKQNSSNRIRKSNPRQRKVGSNEKKSSSTKPSSPSCCASNGSKDDRSSSNSSRKNISSPPKQHYKIEDLGPVTKSPLDTHEYKAVRLAENGLKGFLVSTCEHPLDIGPDSTDGNKVNDSTCVYDKIEEFNREYGNLEPKCDGGNKNKDKHSPNDKSKFSKPSENRKKETMERRKKVKCRRGVYVSDDEMQNARNNLCSVVLFIKAGMFQDPEDVPGLAHFCEHAVFLGSENYPETEAFQSFVDGHGGFSNARTDQENTTFQFYIDFEHIQTALDIFVDMIVNPIFNPSAIKKELDALHSEYEIKHLMDDFRWLAILQSCAMDHHPVQRFGIGTKDSLTKCRELLDRLKEWQALHYTAENMILTIQGPYTVQDLEEMFVEFGSRIQGCGCRPRNPRTTLENYVGQQVFDKKKWNRFYNIVPTVDTKSLAIFWELDPKFGRNYHTKPVQYFSYILNKRDHGSLDWYMRKQGWILSLCINCPEFTFMSTQFHTIFGISFELTDEGFENRLQVVRIVYAYIKFLQMKKASKVIFRELQQINADIFHYRSDKNLIDPTVGYFFNTDSCLDCLRELLDVMSVINSPQDLLLSKFLLRQFDQELLDEFVTNLIPAKALIIFAAKSFEDEAVEREFWCKTKYFTTPMSDALLHDLEVTLPLQDFCFPKENLFAAVSLCFPEKKENIENCSYLQLYTAPKGCVFYGNEACKKGQLPSAQYLIDVFTPTIEDDADQRCIPSMDIFSRMLAYVLDLELGFALSSLVSFDVFKESTMLSIQLRGPSPRLPELAEIILRTIEGFGVFVNDNPAVFENLKNSQIGLYTSAMSESESCVENLANYLIVQRSLFLSDYVSFLQSYSIEDFTEFIQDFKSEMYVRCDLDGCVSRSQAGKVAQVLDILNFKPYPRKFGNLALNRALQLPLGERCLLVANKTKENQTSLVFNYYQIGEDLDTQTHLMLHIMFTTMENMIFEELRTNEQLGYTVELGISDVYGTMGLYVLVHGQADKHTCGYINERVDNFLLTYFNRALKRQQDYVTNIKEYLQEDEKLTWKEMTDFYHAYLLKKGSQYRKLSLQIQGNKLAKSQPKCADQINAKKKEFSSGVKLSKSGGISRHSYFLDLILKDVDEENGYFITDICAFKNSLFCFPNTHYHGVPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MT22</accession>
    <name>A0A1D2MT22_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Replication termination factor 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Replication termination factor 2 domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_10440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the rtf2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000559">
        <property type="protein sequence ID" value="ODM96250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MT22"/>
    <dbReference type="STRING" id="48709.A0A1D2MT22"/>
    <dbReference type="OMA" id="EFRWLHC"/>
    <dbReference type="OrthoDB" id="247013at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006274">
        <property type="term" value="P:DNA replication termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16653">
        <property type="entry name" value="RING-like_Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006735">
        <property type="entry name" value="Rtf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027799">
        <property type="entry name" value="Rtf2_RING-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775">
        <property type="entry name" value="PROTEIN C20ORF43 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775:SF0">
        <property type="entry name" value="REPLICATION TERMINATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODM96250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="327" mass="36088" checksum="6CD693946A49C176" modified="2016-11-30" version="1">MGCDGGTIPKRDELVRTKKKPEQKDKNSERAFRWKHCAITQQRLQKPVVSCELGRLYNKEAVLETLLNKAEVTPDVAAHIRTLRDVKELQLTANPMSSEASSSSAEVGDGYIDVQKSKWICPISGQEMNGTFKFSFIWSCGCVLSDKALKEMRKANAETSECLRCQKPFNFEDVIIMNPTDEEEKERQVEKMNTRRLLAKKNKKSSKKREAEVEAASGSSKATAPEDGLDGDVKVKSEPNKVVNGGASSSNGRVAPKSNGDIAVPVKKSKLSSEAAGSSAAAEKKVKDYSVAKDPNASETYKSLFTTHSTAQTQQKAHWVTYNPFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTH2</accession>
    <name>A0A1D2MTH2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000596">
        <property type="protein sequence ID" value="ODM95995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTH2"/>
    <dbReference type="OMA" id="CAPQNEY"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM95995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="202" mass="22704" checksum="365720EEA56DAB26" modified="2016-11-30" version="1">MVSLLVAIYFQKFLLPVYHGSTSDEVQAAPSLKLFLLCPIIFNSFQIVMAFNLLSAAGKRCEPIIAFAKSNTWFQFSTVMLALLIIKLFFVLWFSSQIPVRRKDIFGVSLIVLETVFKIFGLFIVKEFIDDLKSVLNVLPTPHYYCIYTTAPPPPMAPSPTVPNIAMPSIPYYPQSSTTTQTETNRPRVTISQNRNSAVITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTM8</accession>
    <name>A0A1D2MTM8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_10417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000558">
        <property type="protein sequence ID" value="ODM96261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTM8"/>
    <dbReference type="OMA" id="WRICTSK"/>
    <dbReference type="OrthoDB" id="10473562at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008904516" description="Ricin B lectin domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="49"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM96261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="185" mass="20615" checksum="3655BC454CFD0DD8" modified="2016-11-30" version="1">MKSIVIILGVIQAVFGQRIFPFPGFMTNPVACSFNGPQDAITLRGENFISNYGSNNCLSLKKYASNRNPIVLQQCSWMKYPTSDQLFFFRNGNGGTILKPTRGPTMFDSCVAPTFGQQLSAVQCAPKNSDQTWKFNQVRTNLYQIRQISSGRCLKAESRFDGANASLQACNVLDSMQLWRVCTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MTZ8</accession>
    <name>A0A1D2MTZ8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">POU domain, class 2, transcription factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_10263</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000541">
        <property type="protein sequence ID" value="ODM96412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MTZ8"/>
    <dbReference type="STRING" id="48709.A0A1D2MTZ8"/>
    <dbReference type="OrthoDB" id="6358449at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013847">
        <property type="entry name" value="POU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000327">
        <property type="entry name" value="POU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050255">
        <property type="entry name" value="POU_domain_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636">
        <property type="entry name" value="POU DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636:SF76">
        <property type="entry name" value="PROTEIN NUBBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00157">
        <property type="entry name" value="Pou"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00028">
        <property type="entry name" value="POUDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00352">
        <property type="entry name" value="POU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00035">
        <property type="entry name" value="POU_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51179">
        <property type="entry name" value="POU_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POU-specific" evidence="9">
        <location>
            <begin position="60"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="150"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="POU-specific" evidence="9">
        <location>
            <begin position="376"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="471"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="152"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="473"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="304"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="348"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODM96412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="583" mass="66804" checksum="B6B843FB9AC2590A" modified="2016-11-30" version="1" fragment="single">AVQVAAQMTQTLQQHLQISRAKLHQQSSPHSVENRRIQYHQETPNDDLVPTTSYMELPINETPDLEELEDFAQAFRERRIQLGFTQADVGIAMGKQYGRHFSHPTVSRFEALNLSYKNVCKLKPMLQKWIESMDNSLKNPCATTNPTTSSRRRITRTQIGTSQRVELTRVFIENPKPNSLQMIILAQKLGMRVAVVQVWFRNQFLIMCCSGRFVLASFGEAAEMSQTLQQQLQEIHVQEQQSDWHPPPPPYPLHLLQSECHKGHGQSNQSSDTANVINNEIPYELQIQLESLSPTSSYEWQNWDPSQPFQLKPPPPYPHHLHDHEHSNNTNKDLAFHPQNQQLSPIFTPQPAPCTTPPETPNVLPNNQLVLNPAIDETKNLEEMEQFAQDFRKRRIKLGFTQKDVGGALSKLYGNDFSPTTISRFEALKLSLMNMCNIKPWLEKWLEVTDNLLNKQVVVLSNPPTKSDLIRHKRRKRTKFATSLTTALQRAFTQEPRPTHGQLVALSDNLGIDREVVRIWFCNRSRAKERRLNPLCTFESPPPPIHQHDIFTFHGETQGSGVLLPRSSSPPPYSDNHLVIQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUF9</accession>
    <name>A0A1D2MUF9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein THEM6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the THEM6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000549">
        <property type="protein sequence ID" value="ODM96335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUF9"/>
    <dbReference type="OMA" id="LCTFQDC"/>
    <dbReference type="OrthoDB" id="265761at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00041112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="219" mass="25814" checksum="43488E5B680ED7CF" modified="2016-11-30" version="1">MEFSTLVISLIVILIVLLVIVYLIDINYFMRTIVVVLYAYFVRKSLSILDQSVVSGRVLPFDADTLLTHMNNARCLREFDFGRLDFLTRCGLVKYIICESPQKQPLYAVAHVIRYRRPLHMFMKYKIVTRAVHWDDQIMYFEHKIVTFKDNMVRCIGYSKAIFPFRIEDFLEKYHPGTEKPELPSDLEIWMNFIRANGLNSKKRNEADTDTEQEVWALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MUI0</accession>
    <name>A0A1D2MUI0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_10100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000524">
        <property type="protein sequence ID" value="ODM96582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MUI0"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM96582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="280" mass="31660" checksum="C5FF28429A096412" modified="2016-11-30" version="1" fragment="single">ITGLVILAVGIFSYWESDWRKLKNTPKDEISGWDRVDNDFPPFSLELYFLYPVTICFILSCISLLLSLLTDTRNLKKRAADFGYHVLASIIMLIAGTVYISSSMRIKKLELSWKDGSPMQLLLGLKICAGVLGILVLIVGLISHYESHWRKLYKFKPNRDVWDLVGIDYPKLSIEEYYVAMVIISLIFSLIGTIVYFVVDLTKGTAKLIDLGYHLLMAFLLLIAGSLYISSAKRIGKHEFGWADGSPMRLLLGLKIFAGALTIIQTILYCVVAFFIWKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MV75</accession>
    <name>A0A1D2MV75_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleosome assembly protein 1-like 1-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_10053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000520">
        <property type="protein sequence ID" value="ODM96615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MV75"/>
    <dbReference type="STRING" id="48709.A0A1D2MV75"/>
    <dbReference type="OMA" id="VSPITWK"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM96615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="370" mass="42250" checksum="CFFF03772B844DF5" modified="2016-11-30" version="1">MSAPEETPPVAQMEIAVQDAGKAEGDVKNDVPTIKSPVKQLWNLKFGEGESESITHPPEVERRVKALKKIQVELAQVERNFFKEVHELEAKYHPLYTKFYERRLVITSGKYEPTDEECEASWETASETEVKNNESKAEAAGGEIKKEPTAEAPVSGIPEFWLHVLRNVDRLSEMIHSCDEPILKHLTDITVELMTEPMGFKLLFHFSPNEWFTNSVLTKTYEMKCEVDLQDPFGFEGPEIINCKGCTIDWKEGKNITVRVVEKKQKHKKSGALRLISKEEEVPSFFAFFKPPLLPEEGTEDEDVQMALTMDFEIGQYIREQIIPRAVLYFTGEAVDYETSDLDDDDDDDEDDDTSRTTGENEEEDEENDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVC9</accession>
    <name>A0A1D2MVC9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_09931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000506">
        <property type="protein sequence ID" value="ODM96754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVC9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM96754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="236" mass="26380" checksum="3C4FB001344C6DDA" modified="2016-11-30" version="1" fragment="single">VLWFPPPKRSLQGSKNQIKLNMFFRGARNFSELASSAKIACESINNSLARDEIVVFVKGNRQFLQPLSNSISDSLKLGFVVSNHLLTFQDIEVLVQDANITYVPTDGFNSNTPFNGTYICKKGLEFIEFNATTTQVNTADFTAVPNAGYIRRFSDEVITFSCTANSLSILFLCNFDDRENTTLVYIYNEDRVKVAVLSVTPASTHVKGRCACVTADSKQLVKEWNFEFLGAHCGHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MVD2</accession>
    <name>A0A1D2MVD2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Crossover junction endonuclease EME1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09623</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000476">
        <property type="protein sequence ID" value="ODM97050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MVD2"/>
    <dbReference type="STRING" id="48709.A0A1D2MVD2"/>
    <dbReference type="OMA" id="TMENIEM"/>
    <dbReference type="OrthoDB" id="343092at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033310">
        <property type="entry name" value="Mms4/EME1/EME2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077:SF5">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MMS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077">
        <property type="entry name" value="EME1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21292">
        <property type="entry name" value="EME1-MUS81_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="81"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="188"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM97050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="619" mass="69191" checksum="A9694BDA65572BEC" modified="2016-11-30" version="1">MASSDSDIEVLDEVPCSYSSKPKPSRSERHLFTFSDGEDELPDIDEVPIKSGFSGSYKSKTKSSKPAAKKTKICSTVLEDGHASDVTDVMDEREDDLDSLPSISSRGSTSSSVQVAGFSGGRKETHYDNCVVFDVDDEEDEEKKVSLADKSKKSKPVYEDRQTQDMDDFFQDAGYASLADYLADVETNQKTGNSSSSTKLISGSSSVPSTSGATSSSTKPKQTKDISKPKEAPKRTRSSTENTSREKVMEYQVKASKERTKKKGKSPSKAEEVIKSVPVKKPKAGEGFKMIILQVAVEVMTDPLAAKLIEKEVQFKIIEQPELANSIFFERNQHIKMFGWNEEVHEKVVTQIEPFFMIVFNVEKGLQLLQSQVQKTEGLQTTELCLADWIKKILRKNPGKQLTLLIDGLESYIKKINRRVQKEYRDRVLKGDNAADNTKRKRKVDPSKEPIHLSRNEIQSAFIGVQLQTGINYRYYENPTELSNLLLQYTKSIGDAPFKVEKMNSMEFDWYAVSDCVGGIPVDDDGKGMRSLWLSQLSQFPGVGQESAIAIARVYGSPRELYQAYRRCSCADEGRSMLSNIQVTMGVGPLAKTRRLGPEASKKIYRFFTAMDGDRYVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MWX5</accession>
    <name>A0A1D2MWX5_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA wybutosine-synthesizing protein 3 homolog</fullName>
            <ecNumber evidence="3">2.1.1.282</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_09248</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36635"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.1.1.282"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TYW3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.282" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000443">
        <property type="protein sequence ID" value="ODM97431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MWX5"/>
    <dbReference type="STRING" id="48709.A0A1D2MWX5"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="UniPathway" id="UPA00375"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1960.10">
        <property type="entry name" value="tRNA wybutosine-synthesizing-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003827">
        <property type="entry name" value="tRNA_yW-synthesising"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036602">
        <property type="entry name" value="tRNA_yW-synthesising-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48418:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02676">
        <property type="entry name" value="TYW3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111278">
        <property type="entry name" value="SSo0622-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA wybutosine-synthesizing protein" evidence="13">
        <location>
            <begin position="146"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="93"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODM97431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="335" mass="36832" checksum="67EF54BB04710CCD" modified="2016-11-30" version="1">MTNSPNPHSKEEIGKQTNMAQRRKQQGNSTELVNVRFYENQQRQALTTSDFDEGEGDDLSSVTPQVREDVEYDTEMNPAAVRPAAGSLLTPTQNASEEDAQTENITTGAEADSFGTSSTATAAAGFETRTSSTARVSAPEESLPVSAPTDKSRKGSVDQRIWKLVNLINSQKDSFFTTSSCSGRIILYTWSTGESSEGPADEGTERSKGLKKGCKWLLVSHDEVQPEKLLEAYFAYDGQMDLSFKMEPCILHVQCRLLSDARKLVHVATESGFRNSGMVIGKENRITVAIRSAMGLEVPLSPPQSQLTTSKDKSSCISAEYLNIFSTNFRDEEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY02</accession>
    <name>A0A1D2MY02_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Forkhead box protein N1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_08741</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000394">
        <property type="protein sequence ID" value="ODM97933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY02"/>
    <dbReference type="STRING" id="48709.A0A1D2MY02"/>
    <dbReference type="OrthoDB" id="10070006at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20030">
        <property type="entry name" value="FH_FOXN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049624">
        <property type="entry name" value="FOXN1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46721:SF3">
        <property type="entry name" value="FORKHEAD BOX N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46721">
        <property type="entry name" value="FORKHEAD BOX PROTEIN N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="8">
        <location>
            <begin position="469"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="469"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="192"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="579"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM97933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="618" mass="68134" checksum="0837F0C0CB5B77DD" modified="2016-11-30" version="1">MDWNNVFGMEEGEGGRSAGGNFYVHSHQPGAVAVVSDDGVDVIPIDQSNVVLRSVEEMNAEHGGLEVIEILEGQPMPMDIGEEMSISTTEQERIVGEGESQSNPEGVEATVKQEELEDEDEEVSIDVVPDDEDENVSEQARVVQGDVSEQGNENVPEIPEDQDNIETVDTQLLQEGDTVQVDSVVLKEESIETVQTEEENEVKLVDNKQPADESPRKDSQTEEPSLVTCDMTAEVEEKPSISNMDVDNVELLAPKVKEHLENNTEFMEKNSTVPPVVLDATTGQTVAVLDAANYKPRFVSREKLRRKHPRYAGLSFREIVNQAVVEDKILPDFNEQVLPRKIVDRLRVSGHSIHKPSNAACVVDPSSVIPASIGSTGSSSIGSETDPECLATDEEESESELMQGSVAAWIIPDSIASRTPSPVEPDFDEPQFITTQVGSHTIVEGPPTKKRKQKHHEPQPHTDGKIYPKPAFSYSCLIAMALKNSKTGSLPVSEIYKFMCDHFPYFKSAPSGWKNSVRHNLSLNKCFEKIEKPGNGARKGCLWALNPAKIHKMDEEVQKWSRKDPLAIRKAMSDPENLELIEKGELKRDYSGAGASDDDEDEDFSEPATPLTPAQVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MY39</accession>
    <name>A0A1D2MY39_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase Ocin01_08732</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_08732</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LJIJ01000393">
        <property type="protein sequence ID" value="ODM97963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MY39"/>
    <dbReference type="STRING" id="48709.A0A1D2MY39"/>
    <dbReference type="OMA" id="ALGTREX"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03188">
        <property type="entry name" value="Methyltr_EFM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026635">
        <property type="entry name" value="Efm4/METTL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843:SF5">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="76"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODM97963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="234" mass="26057" checksum="F1966F8E93731464" modified="2016-11-30" version="1">MSGKASESEESGSKNAVAVEDLKPSELGTKNYWEDNFKDELNDFKNHGIIGDVWFGEDIMYKVVNYLSDCHLVTEESKIVDLGCGNGVMILELAREGFKNLTGLDYSENAIELSKTLVTTNEHDATFKMANLLEEPDKLDLGKYDVCLDKGTFDAISLCPDLPQSEARAKYFTNVVNLMTEQSIFILTSCNWTTPELISMSADYLKVQETIPTPQFMFGGKCGNVVSIVVFNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MYL3</accession>
    <name>A0A1D2MYL3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MRN complex-interacting protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000380">
        <property type="protein sequence ID" value="ODM98133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MYL3"/>
    <dbReference type="STRING" id="48709.A0A1D2MYL3"/>
    <dbReference type="OrthoDB" id="5960226at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032739">
        <property type="entry name" value="MRNIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049472">
        <property type="entry name" value="MRNIP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15863">
        <property type="entry name" value="MRN COMPLEX-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15863:SF2">
        <property type="entry name" value="MRN COMPLEX-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15749">
        <property type="entry name" value="MRNIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MRN complex-interacting protein N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="142" mass="16063" checksum="3E13CD6EA7FD4D81" modified="2016-11-30" version="1">MPQILHVLVCVECKTFQVHIVKKSSNKWNCKICNTKQSVQQVYTKGTGAECREVVQKLNQARGQLEENQKLQDLSVAQARQETAPFESFTDAEEPFCEESYESHSENYGYNSVAISSTQRSQSGILSVPPAQSKWQIFLEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2MZY5</accession>
    <name>A0A1D2MZY5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TD and POZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_08070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000340">
        <property type="protein sequence ID" value="ODM98603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2MZY5"/>
    <dbReference type="STRING" id="48709.A0A1D2MZY5"/>
    <dbReference type="OMA" id="YCHVSRT"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="202"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODM98603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="351" mass="39419" checksum="F1C713024AB23FA2" modified="2016-11-30" version="1">MSLPRDSRDSRDFPAVPSSSNGVEVLARNLCDTGFKYNWNIEDYLKGVDQEIDVDSPVYEINVNGLQTKWSLALRYWMDENGLRLTNPVVICLNLVSAVVTSPATSLVDYREQLQVRYQFGIWNPAVKQYEVCPVGIHTIEATSEPTKTLTSIGARDIIILDRHLSGKSIEIFCKIMLVREELEQHSLALDLWTKLRSGENCDVHIHTADGSLVPAHRTILMCRSPVIDGLIDKEGHIKLDMSTPLLTSLLQYIYTDRVDPLDSPEKLLKFAVQLEMPGLKNICEKALIDSITPRNVAALLLIADTFGCDLLKKSALGFCEENSSQIVKTVAWKVMEEVNPKLFEEVCQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0C7</accession>
    <name>A0A1D2N0C7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CD109 antigen</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_07991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000335">
        <property type="protein sequence ID" value="ODM98688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0C7"/>
    <dbReference type="STRING" id="48709.A0A1D2N0C7"/>
    <dbReference type="OMA" id="FAQVMKR"/>
    <dbReference type="OrthoDB" id="6359008at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.690">
        <property type="entry name" value="Alpha-macroglobulin, receptor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009048">
        <property type="entry name" value="A-macroglobulin_rcpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036595">
        <property type="entry name" value="A-macroglobulin_rcpt-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF146">
        <property type="entry name" value="CD109 ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07677">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01361">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49410">
        <property type="entry name" value="Alpha-macroglobulin receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-2-macroglobulin bait region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-2-macroglobulin" evidence="2">
        <location>
            <begin position="408"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-macroglobulin receptor-binding" evidence="3">
        <location>
            <begin position="1086"/>
            <end position="1177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODM98688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1234" mass="139510" checksum="F0D8D00B78355852" modified="2016-11-30" version="1">MDLEKVSEERLSTSVFRIRSEAYLTSGQRVDLGALVLNPVELERDEDDIYNEVANSRDYEEKEIKDVILKHQVKRYLEEAMVEMDLHLPKTAARLIVRAEYTDESGAVAVGELSAVSAFSPSQKFLKVVLKTADAIGVGQFVVLHLYANFAINHFHFLVVAKGMIVSHGTERLNSYWSLPKSFTVVVGQEMSPGFRVFVYCGTRKGEIVTDSIFIPVQNLYRHQAQLEINQAKDRSKDTLELRFVGAPAAYFGASVQRGVRHLMQAGNELTPAYVLNTLHSLEPWNKSLSRLVRRQRSGETPDQVHYLQSSGYAIDSYSALLQSSLIMFSDGFAPRSSFLTSGDECPEERCLTVQGCFRFIEKCDLINHCTDASDELDCDFIDEEDIQHFRVTRISRFADFYDPSDGDWAWTKENIAHGGDYILTRDTPGVTDSWYLNGFAVSKQFGFALIDSPIEYETLRPFLMVCDAPSSIRRGEHVGIIVMLYNKTPKEILVMVSMAGSDDYEFVHVGKDGLMNFDDKHPRFSSGEHQHLVWMGPESEVELRLPVKPTIDQGTISVEITATTQIRSQTVTMDIDVLADGVQIGKHTSLLLDLRNRAFMLKYMNIFVEELPEIPYDIITKYVHGSPAGHVIVSGDVIGPSASLLPVSMESLIGKEGKGTADRIFDLASNTWTLHYLRLTNQLESSVAKNTFKAMNKHFAQVMKRFNANVGWFKTWNLSKPCVWLTSWALQVFAHANFQDWENEFYVEQKIFSKALRWLLKYQNEDGSFSETRWYILHPLNKRMGYMRNMNMTSSNVTLTAHLVITMSQVMGNVDGQLRVEASIGKAKALHFLERQLADMVDPYHIAITAYALTIGDSTEKEFAFSKMHAVRRERAELVYWSPGEVPTNGIVYENQRPFLEAKNNEYWDAIAVEGTSYALLVYLTRDGISPIADSIVTWLNTMRLTDGAFISTVDTVVAFQALTEYANRARMREITDLTVYIEISSQQESEPPEPVKFAPDSVTATHVIDMEMVWGHVNIEGRGAGQAVVQLDLTYGIDWEPFKDTGPVDPFDLKIQEHFGGRNKSILEIEACFRWILLEESEVSGAAVLEVEIPSGYGLLQSDALRLVASGAHPTLKDSVVSPGKTSWFFEFIPPYWTCLNHTVYRWYPVANLTTHRQATIYEAYAPERFINTIYNDTSMRFLDICHVCGSFQCPYCPFYNVASELKRLSVATAILNFAILRYLHNVMIGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N0T6</accession>
    <name>A0A1D2N0T6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low density lipoprotein receptor adapter protein 1-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000312">
        <property type="protein sequence ID" value="ODM98903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N0T6"/>
    <dbReference type="STRING" id="48709.A0A1D2N0T6"/>
    <dbReference type="OMA" id="LPNCDLK"/>
    <dbReference type="OrthoDB" id="9994289at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051133">
        <property type="entry name" value="Adapter_Engulfment-Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11232">
        <property type="entry name" value="PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11232:SF57">
        <property type="entry name" value="RE46159P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14719">
        <property type="entry name" value="PID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01179">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PID" evidence="2">
        <location>
            <begin position="83"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM98903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="23342" checksum="9B164210D6C7F160" modified="2016-11-30" version="1">MEVNNSTSTTFVVKYLGFRTTSHLWGIKYTRNPVDEMVKQAKMQLTSDKQPLPLLKLQVSSAGIHVSPMPQNQNPSCPTGRFPIEAISYGVQDIVYTRVFAMIVVNESQKVTADSLPFRCHAFVCDSRETARKLTIELASAFEVYSKRVKGEGKDGGDARSTSSADGETDKGAVKKKKKFAIDLRSPEEIRKEAGAAGEGEPSEEFPDFSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1G7</accession>
    <name>A0A1D2N1G7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative helicase senataxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_07625</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000302">
        <property type="protein sequence ID" value="ODM99051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1G7"/>
    <dbReference type="STRING" id="48709.A0A1D2N1G7"/>
    <dbReference type="OMA" id="QFLCLEV"/>
    <dbReference type="OrthoDB" id="2285229at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="7">
        <location>
            <begin position="656"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="8">
        <location>
            <begin position="940"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="772"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODM99051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1179" mass="133428" checksum="1A35C0B4EE811A3A" modified="2016-11-30" version="1">MTTSKKAVDESDSDDSVQDVAGKRAENGRMTTSKKAVDESDSDDSVPDVAGKRKIASKPSVEELQPTSPPNEVESPMIVEKSPAAEKTTPRRIMLIDHPPLPRSAQRAQSKTRNFPVPHLVTKLNKLRPHGPQTESRNETLPQSPITDRDFSRLTKEEQKNIRSQKLKDVELKKQQERDEKSSKSPEKRIPTAKIKITSRNRNQGLMESIIGSKTKDNVEELSGNQDAAATKPSTTDTIRENGVNATAMRLLNLSGTIPATTPSVATASRNLDAHTFKVPSLPLSNTVSKGHNNQKSNQKSTSDNIQGEVKNQRSSNASEPPPVPGPSRAIKVPTPTTNQALLKPGARAILSPPGGIGNMMYKEKSGSSSVAAKQKDSCDWKTLISEEDIFLRMFAWRPVWLHEQKEHSEPPPVLKLDGDELVLRTAVVKYQTYEDYMYTYYPLLLSEIWHVISSDASKSIKSESFHQKSSEYRVRITGINREGFCHFARPKPGKPHAKDESWCNVVCESWWEHLNERNFKKDFVILTIFGKDKNNSQIEKKVFGLVVFDHKATMESIGGKVECDPRLKAKGARGYRFREMIQCRISKHFPIDMKQLGYITQISYIMPKIREFRGLNCLQSSKLFNHIVSPPKINNPWTSSYPPMSSHQMIRICHQLNSEQQSMVNYITSRVFSNDPELMLMHGPPGTGKTTTIVALVLQLIHSYRMKYKTGTPRILICTPSNAAIDEIMRRLIKAINDLPSTDRKINMLRVGDGCAKELEKYTVGFLSREKEEEKSTSKTLKIELESLNHEVEEKEKEVNRKRSDPNRCLIQYEALLCKLQEVKGRRESVLQDLNMNKKKGKPVAGEKSRNDVIKNTNIICSTLSGSSNSLMRNAFGKFISEEQKHFMCCIIDEASQTTEPETLLPIGLEIDKLILIGDPKQLGATVLSPEADKKNFFQSLFKRLFEHYDRPDNVVGLQNPVMTLRRQYRMHKEIVHFPNAFSYDGKLETYYKQPDGYLLRPYYFLNLRQIENVDEVELVKSVLEAIQQVLQTTQTTWTVGVITPYSAQKQSIRNALQDKTFSALKSIQVDTVDGFQGQERDIIILSCVRTEATGFLKSATRLNVALTRAKHSMYIIGDLNCLSKDNMWKCLIQDAARRGHTYKVNPDFRIHIKALSTDLINNLKNSEKQRDQNSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N1H0</accession>
    <name>A0A1D2N1H0_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_07526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000296">
        <property type="protein sequence ID" value="ODM99146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N1H0"/>
    <dbReference type="OrthoDB" id="191150at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF9">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODM99146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="299" mass="34227" checksum="63712D9D99220D15" modified="2016-11-30" version="1">MKPGSSRISQIFREENAKGTDKKAIMLKKSTSSIRSESGFHHAIEALLSLENASVIFMQRLLDYEEIQAAGIRFHEDTVDLAYQILNVQGTLLFLMEQHKIKCSAFIVYTKRSFENILYDVHGTVVLKFVGPSVIMSRMVSRMTITDNDDRLLGYVKEFGKRVNYSVYNARGERLFLVVSNSYIPSSSTPFSILYRGQNIGVIKFGWKHVYHDLPYIDYETTGVEFPADMDEREKALLIGCMMLIEFSWYSPLTKLRLSMLLVGLILASLGIIVIFFPFFVESTTQDPETASFFKVQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N282</accession>
    <name>A0A1D2N282_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000286">
        <property type="protein sequence ID" value="ODM99350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N282"/>
    <dbReference type="STRING" id="48709.A0A1D2N282"/>
    <dbReference type="OrthoDB" id="7207684at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46901">
        <property type="entry name" value="GH04942P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46901:SF2">
        <property type="entry name" value="GH04942P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12961" checksum="209EA38523A8790B" modified="2016-11-30" version="1" fragment="single">MMAKLRTITGSITPWLIAFTLCVSFMNSSAHVGLTFPPARKFDLDFLDNIRTKPPCGMPRGTIKTSLVSGSTFNVTWHLSYPHRGGYRLELMDSQERTLLDLTPKNGNESFIKGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2I9</accession>
    <name>A0A1D2N2I9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_07569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000298">
        <property type="protein sequence ID" value="ODM99125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2I9"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODM99125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="225" mass="25656" checksum="16D96E0747DAB4D3" modified="2016-11-30" version="1">MTLRLHFETNFGEMDMETQDLKSEEKGQEILSLIYALHNMKQKSSKSLDYKLKALFASPTEKVIKKANKLLRTVSTEVCPDDCEPLGLRDVEAFKSVLRKFGFGIMDALTHRACKKAIGAIAAFVKNWNSVVESSEEKFAQGYGKIYCSKLCITKLSDITNVFNGLRKQCKNDSFPEALSTFKEEHIIDYVLNSITYYNGATIIAKRKVERELTLNRRSWCVSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N2P5</accession>
    <name>A0A1D2N2P5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Delta-sarcoglycan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">Ocin01_07180</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <location evidence="2">Sarcolemma</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sarcoglycan beta/delta/gamma/zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000275">
        <property type="protein sequence ID" value="ODM99510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N2P5"/>
    <dbReference type="STRING" id="48709.A0A1D2N2P5"/>
    <dbReference type="OMA" id="SPHSICA"/>
    <dbReference type="OrthoDB" id="8881719at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016012">
        <property type="term" value="C:sarcoglycan complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060047">
        <property type="term" value="P:heart contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006875">
        <property type="entry name" value="Sarcoglycan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039972">
        <property type="entry name" value="Sarcoglycan_gamma/delta/zeta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12939:SF10">
        <property type="entry name" value="EG:4F1.1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12939">
        <property type="entry name" value="SARCOGLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04790">
        <property type="entry name" value="Sarcoglycan_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ODM99510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="330" mass="36022" checksum="2F1831AF60A47123" modified="2016-11-30" version="1">MRDQSVIQQRRHPQQNPQQQQHPGEMENEWLSSDETRKNFIAKYHEGCQVGLYGWRRRCLFLVLSILLLLVIVNLALTLWILKVMEFSADGLGPLKVIPGGIQLRGEAMVLDNLVASKIGSRKGQPIHIESSRNISLLSRGADGRVHNKLFIGDDKLEIMASGMKITDTRGRLLFSADRKEVLVGAELLRVTGEGGAVFHGSVQTPLVRPEAGNELRLESPTRSLNVFALHGVAIESRAGDLSATCLTELKLQSKAGSVKLDAPNIYLPRLQTASITGAKLPTAGGSVYPTSTISRSARPEVYQVCVCGKGRVFLAPPEGPCVADNDVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4B3</accession>
    <name>A0A1D2N4B3_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translation machinery-associated protein 7 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Coiled-coil domain-containing protein 72 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_06610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000235">
        <property type="protein sequence ID" value="ODN00072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4B3"/>
    <dbReference type="STRING" id="48709.A0A1D2N4B3"/>
    <dbReference type="OMA" id="KKGPMNT"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28632">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00031894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN00072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="64" mass="7022" checksum="A278739B5DA9A0CD" modified="2016-11-30" version="1">MSGREGGKKKPLKAPKKDNKEMDDDDLQRKQKQKEEQKALEAMKAKAAQKGPLTGGGIKKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4R6</accession>
    <name>A0A1D2N4R6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division control protein 45</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_06410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000219">
        <property type="protein sequence ID" value="ODN00270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4R6"/>
    <dbReference type="STRING" id="48709.A0A1D2N4R6"/>
    <dbReference type="OMA" id="HNHLDTS"/>
    <dbReference type="OrthoDB" id="10258882at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902977">
        <property type="term" value="P:mitotic DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003874">
        <property type="entry name" value="CDC45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507">
        <property type="entry name" value="CDC45-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507:SF0">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 45 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02724">
        <property type="entry name" value="CDC45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN00270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="384" mass="43907" checksum="3C347117A23341AE" modified="2016-11-30" version="1" fragment="single">AAPGSAEMLVDHYRRDFMDRIVGHRVVIITNQDVDAVCTVKILTALFKTEGIQYILLSCCGISDMKTKYDEYSSQSDKYILVNCGATIDVLETLGEPPKEKLFFILDYHRPINVLNYYNTTGQVFIVSVLEPEETIPDIKSTPYIVSMLRTWSLEGSRKLHQMLAYLGLPLVEVKQKYMNMSLDLRRQLVEMFSSETVVEKYKLPDVIFGSFVAEIGFRPKFNALDVQLSTLAVLEDPDATKSSEEKFLNAVQCLNVRDADNHKAGIEKAKTMLKQLNSQIQMMVEMKQVQEVGPFLFVQLTDSIIDFNYFKRPTTIPLLANFLQHAGIRSGKRKWRQSPWIIMIPYNKNTLLLLVFQLEPLSKPTRTYSLRCSVSSNLRCQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N4T1</accession>
    <name>A0A1D2N4T1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome b reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_06437</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000221">
        <property type="protein sequence ID" value="ODN00242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N4T1"/>
    <dbReference type="OrthoDB" id="907479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043205">
        <property type="entry name" value="CYB561/CYBRD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10106">
        <property type="entry name" value="CYTOCHROME B561-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10106:SF0">
        <property type="entry name" value="LD36721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="231"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ODN00242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="266" mass="29102" checksum="683F665F0FFDEF8C" modified="2016-11-30" version="1" fragment="single">SIATNAVNCILLIFVIIWVYQAGGFAKSATEPHAALMVTAMILFGSIASTAFRFAISCRLKTVKYIHAGIHSLAFILGSYGIWIKFDEKSKVKPNPKPHFGSLHSWYGLTVIIVYLLQARKRLIGGGLVFLLPQTPWPLRIGAKPYHKAVGVGIYNLAGIAALTGILLTITYRFPATILKPVAGYSPASVENVATMIPVLILISCVMTTYLILETRFRRKPPPVFQEPIVFEDVQPGEDNDVTTGEQGESNENKDSGLNVTNDEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N5X1</accession>
    <name>A0A1D2N5X1_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000192">
        <property type="protein sequence ID" value="ODN00680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N5X1"/>
    <dbReference type="STRING" id="48709.A0A1D2N5X1"/>
    <dbReference type="OMA" id="RPHAVHM"/>
    <dbReference type="OrthoDB" id="1918363at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="3 5" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN00680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="817" mass="92392" checksum="FE24520507EAE7E8" modified="2016-11-30" version="1">MRWSWWDEGIEQAEKLTAEIDATNELPRVQRNLRQVLEAGQQLLCRASQGVAGAPNAETKAAVFLGTKGVDITKLNDSLQPLYNIHTIEGGRDTISETNIESFLKLERTTALINVAETTASNILAQLEEKIMLQVDNEWKRERSEIASVMSGSLKPIEFDTQMYDRTVEASSILSKTAVTYAYEVDRYNQAVINGLPRPNLCERFELAAKNTNDRHLQELWTSIAEVTSGLGGEPLDKNALARIRSSDVYAKNFVSRAKKHLQQSFFSKLTREVWERLGETQTGGVPAVIPLIRSYIALKGLGALMTLEQGAGDAGPVWLIVYLCLRSGKAEEAATYMKENIGNTEFASILQAYSVTGILPYDVECKLRVDYRRAVRHTSHDCYQRAVYCILGGCDVEDDHSEVAQRLEDYLWIKLSVLRYNSDGAYSADFLTLPLFQEMIVEKYGEYYFDAVKQPYVYIQALILTGQFEASIEFMSRVSGMKSHAVHVAIALQEGHLLLTSDPKSPILFRSKDDPPGLRWLNYSRVIVGFARTLRGRNSKDAINYLHFLRSMKDKDGNDLFSICVSDLILESRDFEYLGHMNPDGCRTPGLLETMGINVLPIIVRCASESELRGLTEDAIILYDLASKHDDALRVLCRVIAKHVTELPLPESARQRIRKLAISFAERYQANPPKVTDMSVITTFYVLVDFMTFFDEVFSKRYETALTVIQKLKIIPLHESEVEKCVRDFHGFQEEIRMNVPDLIVATMETLYAKYKKLKDTKKSNYFAADNGGQDNQFLLEVKAQAKALVTYCGIIPYFMTGDTYTKVMQIEVQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6H5</accession>
    <name>A0A1D2N6H5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_06002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000192">
        <property type="protein sequence ID" value="ODN00685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6H5"/>
    <dbReference type="OrthoDB" id="6781779at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN00685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="327" mass="35829" checksum="8C762E0E9738FA44" modified="2016-11-30" version="1">MANEMLPTSLPPPSSPNVSSSSPFPLKTLGSSTSHESLAEPGTSENHHHHPYSSSHLVELPSSDEPAGGDGQPEAEGHHKCYVCLPPDKTSRDAEEILSIFPEETRQRIPDCASFGSHNAKHFEFKCPPEFVGCLLRIHGRNESRSCFKHPLNDCKTANSVEFCYCTGALCNQHRPEILLEESESDERQRAQLEDEKEERETRKIWQKGETDDEDLLGPHHVDIDGMQDDIGDYGSGSEPPPGVIHQYTSTPKPTLIPNLRPDTRTTTPKSTSGAPGSTIVMLSAFNIPCTSITIPATALVASLVPLLLPFIIAWNLSSLQPLVKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N6W2</accession>
    <name>A0A1D2N6W2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_05960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000190">
        <property type="protein sequence ID" value="ODN00706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N6W2"/>
    <dbReference type="OrthoDB" id="8291552at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN00706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="78" mass="8701" checksum="2ADD1A2C29EFEA25" modified="2016-11-30" version="1">MSNRDNPVLKTILGSFYGTGKGERWGKICMESSFMQSGDLSYRPPRYLYVNAFTEMNYFTTGPMSGTSGQLLETVING</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7J4</accession>
    <name>A0A1D2N7J4_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Phosphoriboisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_05460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000166">
        <property type="protein sequence ID" value="ODN01233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7J4"/>
    <dbReference type="STRING" id="48709.A0A1D2N7J4"/>
    <dbReference type="OMA" id="INQWPGV"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006014">
        <property type="term" value="P:D-ribose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000018">
        <property type="entry name" value="Ribose-5-phosphate isomerase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934:SF0">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN01233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="321" mass="35263" checksum="F297D371E4A2C2F8" modified="2016-11-30" version="1">MLRRLIFLGEVNGKQLLALGSVIHRDTHIHGSARKLFCGPLLQKVSAINMGDDQKSLLDKAKKLAAYQAVDDHVKLCKTSKCIITSSLIGWTSSGHREWNNAVYAVERIAQRAREENLNLICIPTSFQAKNLIISNGLQLSELDVHYPIDVTIDGCDECDQDLNVIKGGGGCLLQEKIVASASKKLIIVGDFSKESRYLGEKWKKGIPLEVAQMGARVVLEKLQKFTDSVGGSVIPTKVRQAVNKMGPVITDNGNFIVDFQFGDAMKTGELHNAQSVESWLKSIPGILETGLFVKMANQAYFGQPDGTVKSTHERIIKNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N7L6</accession>
    <name>A0A1D2N7L6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonuclease P protein subunit p20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_05427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000164">
        <property type="protein sequence ID" value="ODN01260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N7L6"/>
    <dbReference type="STRING" id="48709.A0A1D2N7L6"/>
    <dbReference type="OrthoDB" id="416729at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014612">
        <property type="entry name" value="Pop7/Rpp20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15314">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15314:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12328">
        <property type="entry name" value="Rpp20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN01260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="230" mass="25594" checksum="29353B7441E1BC34" modified="2016-11-30" version="1">MKVIMADDKSPPEVLEGARTASPIIKKQEYDNISETNTSTASSPRRVQNRERRGGQHKDRSSGTGVEGHQKRGGGGGSTEKEGKRVAPSSASVAEHQQLMGLEPVVNRRKRVDTNTQAPPKELIDIKQNDVFVSEKSHFVGQLSKCKKLFDKGHSEIFLHGLGKAIPRAINIAFELKKFYHNSVDYTVNTSTVEVYDDIICVDDTEQPPVQRSRNVSSVNIRIYRSVRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N835</accession>
    <name>A0A1D2N835_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_05267</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000152">
        <property type="protein sequence ID" value="ODN01433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N835"/>
    <dbReference type="STRING" id="48709.A0A1D2N835"/>
    <dbReference type="OMA" id="MAPQMIP"/>
    <dbReference type="OrthoDB" id="10005095at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017147">
        <property type="term" value="F:Wnt-protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07459">
        <property type="entry name" value="CRD_TK_ROR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05048">
        <property type="entry name" value="PTKc_Ror"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000116">
        <property type="entry name" value="inactive tyrosine-protein kinase transmembrane receptor ROR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000139">
        <property type="entry name" value="inactive tyrosine-protein kinase transmembrane receptor ROR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.20.10">
        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020067">
        <property type="entry name" value="Frizzled_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000001">
        <property type="entry name" value="Kringle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013806">
        <property type="entry name" value="Kringle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038178">
        <property type="entry name" value="Kringle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041775">
        <property type="entry name" value="Ror-like_CRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002011">
        <property type="entry name" value="Tyr_kinase_rcpt_2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF611">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00051">
        <property type="entry name" value="Kringle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00130">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57440">
        <property type="entry name" value="Kringle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50038">
        <property type="entry name" value="FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00021">
        <property type="entry name" value="KRINGLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50070">
        <property type="entry name" value="KRINGLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00239">
        <property type="entry name" value="RECEPTOR_TYR_KIN_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 12" id="KW-0420">Kringle</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="17">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="18">
        <location>
            <begin position="164"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="301"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="605"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="605"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="649"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODN01433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="767" mass="85886" checksum="242119080A28A955" modified="2016-11-30" version="1" fragment="single">MCAKRFIENRTIYVHSEESQIVIESKLQEALKVIQHSEDISARCSEFAIPSLCYSAFPLCPDNLGNTEENLNFVSPRRLCREECELLEHDLCRQEYALAKRHPLIGQQLAIPECAELPPLGSKESASCIRLGLPHLTRHCGGSHLLQRKGHELQRNCKGNGVWPWSHQLSFKSSDYAELMGGHNYCRNPGGIEQQPWCFSNSEHFRKEPCKVPKCGIFGYANTEFVDIAESKIWLPVTGGVAALLLMMFLICIICCCRRGRSKMSATKSVGSRGSMQGLEMSSLLRKSGQTKAPEIPIGNVQFLQELGEGAFGKVYKGEAILRPGDPLIRVAIKTLKASATPKTRQDFQREHELMAELKHPNIVCLLGVITKEEPRCMLFEYMSQGDLHEYLISHSPRNDSTHHQGNDYGSHKVLEPNEMLFIATQIAAGMEYLAAHHYVHRDLAARNALVGESLTVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPPESILYGKFTTESDVWAFGVVLWEIYSYGLQPYYGYSNQEVIEMIRSRQLLPCPDLCPPRMYALMVECWAEMPHRRPSFEELSSRLKQWLLPLLGPNSHFSQHLNYPMAAPGSLSCASNNSMSSHQSSNTGPTSNNTNSTNISNLAMQQQQQQAWQQQQQYPRTPQNHSGPQQSPSHCVAYQSTPIVHCPVNCGTPVGMVNGGRFSPQQTLHSFQQPGVGTPNMAHAHAHFHGNSGRVVTTHTHAHAHTHGYPQSIGSSNSAHSHSPYRVLMESKATNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N918</accession>
    <name>A0A1D2N918_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">Ocin01_04940</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000141">
        <property type="protein sequence ID" value="ODN01741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N918"/>
    <dbReference type="SMR" id="A0A1D2N918"/>
    <dbReference type="STRING" id="48709.A0A1D2N918"/>
    <dbReference type="OMA" id="HIFAEMA"/>
    <dbReference type="OrthoDB" id="6499751at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005700">
        <property type="term" value="C:polytene chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000078">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000044">
        <property type="entry name" value="Histone H3.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ODN01741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="136" mass="15328" checksum="5158ED279E6F9E1C" modified="2016-11-30" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2N9F7</accession>
    <name>A0A1D2N9F7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_04803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000135">
        <property type="protein sequence ID" value="ODN01889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2N9F7"/>
    <dbReference type="OMA" id="LICEIHQ"/>
    <dbReference type="OrthoDB" id="8251490at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006631">
        <property type="entry name" value="DM4_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07841">
        <property type="entry name" value="DM4_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905256" evidence="2">
        <location>
            <begin position="20"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN01889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="249" mass="27660" checksum="09021209AE35655B" modified="2016-11-30" version="1">MGKFRYILLASVLLAVAFAAPKEESESTEVEAKAEKKSTPAERQVDVVNEDWGTWLASNYGGVAVTGVALILILAGVGYGVYHFYYVQYGLGATGYAADNQYGQPHTFNQYPGQYPGGQYGAYTGRALDLGSQWNFTKVLEYIEIAQKTYEGFDWQDLNCQKRTLCELVQKQNEPWGETGRKLANSYVYRVMDALDGVPIPRVIQTYLKEYKEAISQGKNSSKDCGQVYANCKFSIKDVLAKSAAKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NAP9</accession>
    <name>A0A1D2NAP9_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'(2'),5'-bisphosphate nucleotidase 1</fullName>
            <ecNumber evidence="15">3.1.3.57</ecNumber>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">3'-phosphoadenosine 5'-phosphate phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Bisphosphate 3'-nucleotidase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Inositol-polyphosphate 1-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">Ocin01_04321</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1D-myo-inositol 1,3,4-trisphosphate + H2O = 1D-myo-inositol 3,4-bisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:70319"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58414"/>
            <dbReference type="ChEBI" id="CHEBI:83241"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:70320"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15553"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58282"/>
            <dbReference type="ChEBI" id="CHEBI:58469"/>
            <dbReference type="EC" id="3.1.3.57"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15554"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.57" evidence="15"/>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="LJIJ01000115">
        <property type="protein sequence ID" value="ODN02330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NAP9"/>
    <dbReference type="STRING" id="48709.A0A1D2NAP9"/>
    <dbReference type="OMA" id="QTEADRC"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004441">
        <property type="term" value="F:inositol-1,4-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000006">
        <property type="entry name" value="Bisphosphate nucleotidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000012">
        <property type="entry name" value="Blast:Putative inositol monophosphatase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050725">
        <property type="entry name" value="CysQ/Inositol_MonoPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028:SF5">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0452">Lithium</keyword>
    <keyword evidence="7 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="18">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ODN02330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="346" mass="37631" checksum="C6B2BE04F83D094E" modified="2016-11-30" version="1">MIPITDFHPNFIQFNYSLEESRSDPIPSINIITELHASVQIIFSSSAKPLFCGVRYYNTKMSLSESTAPLLLRLVSEACTTANTAGSIVRKVLLSGELGVVDKGVNDLQTKADRCAQQYIVQRMKQSFPKATIIGEEGEDVSENLDGLLSPATTPSEPLFPEILTKAVPEKLLEISEDNIVIWVDPLDGTQEFTKGLVGHVTTLIGIAFDGRPVGGVIHQPFYEADGVKGRTMYGIPEVGHGVMHVSKQPWQHLQPDDVLRVGGAGHKAVLLIEGRAHAYVFASPGCKKWDTCAPEAVLVSIGGVLTDMDGKPYRYSKDVQHVNEGGLLATAPGVDHSWYLKSIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NBZ7</accession>
    <name>A0A1D2NBZ7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Trafficking protein particle complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">Ocin01_03920</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">May play a role in vesicular transport from endoplasmic reticulum to Golgi.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Golgi apparatus</location>
            <location evidence="2 10">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000096">
        <property type="protein sequence ID" value="ODN02761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NBZ7"/>
    <dbReference type="STRING" id="48709.A0A1D2NBZ7"/>
    <dbReference type="OMA" id="YMVKFDD"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000005">
        <property type="entry name" value="Trafficking protein particle complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ODN02761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="23640" checksum="4346EBB58EB06B11" modified="2016-11-30" version="1">MQPNNDGSNGVGDPNANLSSMITLLQSKAKTSILDKSLSKGKNEVHLSCFALLFSEMVQYCQNRSNSVSELQNKLCDMGKQVGLKTIDLIVLREKNYKREVKLLNILLFIKSTVWKTLFGKEADKLEHSADDSRQYYIIEKDPLVNRFISIPKDKGSLNCASFNAGIVEGILETSGFPAKVVAQWHNGITYYVIEFDESVITRDKQLDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NC34</accession>
    <name>A0A1D2NC34_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_04044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000102">
        <property type="protein sequence ID" value="ODN02645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NC34"/>
    <dbReference type="OMA" id="RDECANS"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="923"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="720"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="923"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="953"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="1168" mass="125579" checksum="66854A5F3EC62C55" modified="2016-11-30" version="1">MNSERNPHLLSDPSGCGGGSGGGCVIGSSSGPPIHGYGSPQGSGVDMQEPLLMANHVQYQHLLGSNPQFPQQHLSTHHLQQQQQQQHHQRSFYGSTNYNSCASNNSANSSNDSSGAGVHTTMNQIRGNQNSYCNTNSNAISSSTNNGIFYESAEVVDQSQYYHQQQQQQQPHHHSHNNSHNQHHQQQHHHHHFHHQQQHFDNNMHLQKTGSSTNSCASLENNVNLSGECVGGDGGASGTNFYGFYNQSGQYGDYHQQQHHHQHHSQHHHDGVYNTAGDGSGVNRMHHQYYRQEGSSSGSTDTSANSVPVGHPNYFNSNIPTQNYPAVSGTSSTPPTRYGSPMIFPNNHSHQQQQQQPNTNYGTQQLQQQQQHPHHQNNMGQIPIRRNSIESFSSEPGDNMHSSYTARYGCSSTTNMNHPQLQQISNHNMFPTSGESTNTSGMVKRECMSAGGNVNDTMTSRGSPSINPMTPNSTPTSWSPHPPQGGYFPSSSPSNSCTSSSSPNPCSTNTPTPTIRTTFINSSYPQAGQSGVISGESANCRTNHGNFYSQQQHHQQQHPTQFKSCAYEQSQQHHDIKDGIQLVQSNSATNSLKAASAVKHRSLSLSMPLPSYLENNGSSRSELDGNFVNHHHRQIQHHHHHNHGYNPMMDGSQHHQQCTTTGGLIPPDQNLLTPNSDDDMPFRTASAGGQSDLDSSYETMGDEGCSSSTSASHCMPMNTSGNSACSGSGDNNNGSSMTPDLHSMSIDTNEPDCHHHHHHNHHNNDLPFSTSGPSCMQNHVQTSLSMGMLEIPNSTVALCTTNVDDLDDSSSDSSDELHNVISAVVENSSIETPENTMMGDEDDDDVIGQGEGNGDDNCPSESGGDVNRVVHYHHTATPDNQTDVNVISTTTTDDVDNDNCSESSMNNINSSFTADMFSSNDNGTGLNKNGSGSDKDGIDSNSFACIPEGTHFDEDDDEDNDDDDNASVNSSFSLQLKSCSNTTSSFSETDKDNVVSATTTTTSLTFGASFRTNCAGSGSGSSTSISGIGGGGSSINDKCAANNDSESSANSKNSSSCSSANNGNGMGNNSATTTTSSSCKAIGIIISSSNSNIITSDANGNRVSIPKGWKREILKGSSNENNGSNNNTSGVLYISGRTSQAPALFQQFSPYHHYHNSGRGELARGIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCB0</accession>
    <name>A0A1D2NCB0_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">von Hippel-Lindau disease tumor suppressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_03943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VHL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000097">
        <property type="protein sequence ID" value="ODN02725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCB0"/>
    <dbReference type="STRING" id="48709.A0A1D2NCB0"/>
    <dbReference type="OMA" id="MNQRVEQ"/>
    <dbReference type="OrthoDB" id="413400at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05468">
        <property type="entry name" value="pVHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.780:FF:000001">
        <property type="entry name" value="von Hippel-Lindau disease tumor suppressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.750.10">
        <property type="entry name" value="von Hippel-Lindau disease tumour suppressor, alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.780">
        <property type="entry name" value="von Hippel-Lindau disease tumour suppressor, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037139">
        <property type="entry name" value="VHL_alpha_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024053">
        <property type="entry name" value="VHL_beta_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037140">
        <property type="entry name" value="VHL_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036208">
        <property type="entry name" value="VHL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022772">
        <property type="entry name" value="VHL_tumour_suppress_b/a_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01847">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49468">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="von Hippel-Lindau disease tumour suppressor beta" evidence="3">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN02725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="175" mass="20484" checksum="71D9560E62DEDF8D" modified="2016-11-30" version="1">MSNQINPPENADQPQRRPELRSKTSTKHAYIRFINMTHRRVDVIWINYEGVRVKYKTLEAGEYFDVTSFVNHPWIFRDAETHTKLVVSSKEVFDVPEPVYLKLQNGRVQATRAIVAITTPLYSLHEWAIQAVLKNLREPADVNDLDIPNSLKQELRARCCYTIPMLQYTRRTNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCN9</accession>
    <name>A0A1D2NCN9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000089">
        <property type="protein sequence ID" value="ODN03023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCN9"/>
    <dbReference type="OMA" id="IAMIEIV"/>
    <dbReference type="OrthoDB" id="10440287at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN03023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="173" mass="20148" checksum="5E4AF454779E97B8" modified="2016-11-30" version="1">MCGIPYEKQARIIAIIEIITSLFGFSFVSIATLILGFSPDLRREILHESEDNFFNIVLHFSLPEKVSSVLIPIIYFVCEFSLAVFLYHSVSRRNYNYLRVWYIVTITICMTALYFFLPGVFFTEDSYYFIVVFIGSYAFTCYSVYVAHSFMTELRMEGLHAPVVAWEEDIDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NCP3</accession>
    <name>A0A1D2NCP3_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M-phase phosphoprotein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_03859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000094">
        <property type="protein sequence ID" value="ODN02845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NCP3"/>
    <dbReference type="STRING" id="48709.A0A1D2NCP3"/>
    <dbReference type="OMA" id="CERYIFG"/>
    <dbReference type="OrthoDB" id="20403at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019324">
        <property type="entry name" value="MPP6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13582">
        <property type="entry name" value="M-PHASE PHOSPHOPROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13582:SF0">
        <property type="entry name" value="M-PHASE PHOSPHOPROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10175">
        <property type="entry name" value="MPP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN02845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="284" mass="32013" checksum="16329C880F329AC0" modified="2016-11-30" version="1">MFTMSGIGAKLSRHVLGMKFMRKTKDQIDKERVEKVHREHFAPAESETSASVKGDAASSGFNKTPGIASRKNEPTTSKSSLTVEELWSYNQCERYIFGRQSFGGFNPVVENNVKKGIWKPFYLEESECQQDDSEEEEGIKKNQSDVDVSDEEMSKTYGSLIGTLAKRFTRKNKQGAGGKGKNRGNEADNSGQNGGKKPNKRGRFRKNKKEAGGSGDHNNQSSHQQQNRGWGSKGSKKRQRESTGSTNYEYQEERNSRPKRRSDDRNQDSGIPQKKRKFLKPSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFH5</accession>
    <name>A0A1D2NFH5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02706</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFH5"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="673"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="751"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="613"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="764"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="816"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="832"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="845"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN03982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="924" mass="97412" checksum="D5E2E4E5D6B947A9" modified="2016-11-30" version="1">MESALGKQSGNFTGKGESQLQPVFQMLRKSTPGGSSTTTTTTSGTGLLSSSPSTASSRDLYHHSPNRHHHAQYIRSSRGESVAQQHQRATPPTSSSCTLEARSSNSTPKRGANSSANNTNQSHLSRTSSGSDISGGVGGNSIPSGGGGGGGVILRSPSHHHRQQQHQQQQHCCGCACSSSSPSSSNKGSRDNLLRNVVTRNNSPTRAHSPIHHHQVQHSHSCCCANQHQQQNQHLNLNHSTLVHRIRDCPVDSHPRLLTTTTSSNVNPNNQQLWLFGKDEGLDDEEDPNDSVGVGDERVVRRQDVVSAGPSHGCHHPSPLIVQSGASAQYNAGGGGGAIGTPTNTNAGGFGFFKFQNPSSSVASPHPELLLPMDFIQVLIHQHAKTIVALQDLQREVSTLKDFRTSLLHSLPATAAPTAPSGLSDAVWTTGSAIGVGVSSATTAAIATAPSSTTGAVVGVVPNGSSSSAPKIPHPDSGFSTETKSTNQKSDAESDDELYSLLSLIQCKVQESIIRNDYLLTSHQNRTATSSHRSSSNHRRQGEKPKERLGKLDKVLGNCDKVEFRKDFISRDVIRGVLGAEKTELQRQLFFALVKIENLKSVTKEQKTVDSRVYALSQENEQLRYKLKEMEIELEGTKATLRILQKNSYSPASPSAAAALVVSAAKLSTPISPSSTVLPEAPCHTSTPHHLHPSSRLVVPTTTWESDSLDNTDPADYAIPGATAVATIASSSANSTRQRLIQKLSDIESISTNNSSSTHHHHSSSPTTNISRLSNNYCTNSSSSNSSNNSSGGNSTSSKKSPAPKPPVIIEHSIMNTTSSTSPSPSSNPNSATSKQQKSASPVGNKSMSSIKSNNSSIPIAVSRLKAKGGPGSTGPASNNNNNNNNVAGTGKTTPVGKLKPGSGLPPATTGNGGIGTIWANWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NFQ6</accession>
    <name>A0A1D2NFQ6_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-tocopherol transfer protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_02564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000055">
        <property type="protein sequence ID" value="ODN04108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NFQ6"/>
    <dbReference type="STRING" id="48709.A0A1D2NFQ6"/>
    <dbReference type="OMA" id="DSEEHYI"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="90"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN04108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="263" mass="30578" checksum="06F2F8E6363A6C6E" modified="2016-11-30" version="1">MDNEMISKERKVLGQLKKYIQTDPLFQDLEDLLTDDFLLAFVRGRKYDIDKATKTLHTFIKLRRVDYRDFFQRFLPSYIKHGFDTPIRVQGVLKNRDPQGRFVGIDRLGVWDPDRVTPEQGGMLLLMYGLDAIKSEQLQREGVVIIVDCLHISLKHAKCLNLSLLRMLAGIYIDSLPVKYKSIHLVNHSVIVDLFLPMIKMFMSRKLRQRIVIHSSLESLHEAVPREILPESLGGPLSDEDAFDSKFEQRIIDSEEHYIQLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG62</accession>
    <name>A0A1D2NG62_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein kinase ATM</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">Ocin01_02433</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LJIJ01000050">
        <property type="protein sequence ID" value="ODN04229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="48709.A0A1D2NG62"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000023">
        <property type="entry name" value="Serine/threonine-protein kinase ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="16">
        <location>
            <begin position="1834"/>
            <end position="2453"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="15">
        <location>
            <begin position="2563"/>
            <end position="2883"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="17">
        <location>
            <begin position="2910"/>
            <end position="2942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2853"/>
            <end position="2876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ODN04229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="2942" mass="335286" checksum="B6F5968F7540C9D9" modified="2016-11-30" version="1">MDPLQRMIAEMKTATRITDRKNAAQSFINYLNNDEDDVCETLDFNSVNPEKKASDRMTWTRLFAEVRDYFVKETEKGTMTHLNKLFYFSVIDQVFTKATSNRPWLQWSKVYDFILTHLQKDRHAALYGPSLISMLERFLSIEFYGTVIDATAWIELTNIILKCYKKYEISTVSILRCLNHCIARGSLYGQVISTLRSKVVNFYTKILQDDKNAIRQDIIPYLQGLTTLCALNAFEFRSILCKLGEDVIPSILQISSFSDEEETALIDFLMVQYRLHMPCDVDMNSDSFYAYDPQNWKEILRSVYSYCIDKIEDTAYKRNSLNKTDLKVSEELIQLAANCTKQISSSAFTENEDSEEGDGVLQKKKMRYKSFDTIINDVSRRPVSEGVLVWTSYLSVVLSDFPELVGTRPNLSSLIQLGNSMFNTSFINRREFYVYFLSVLRAEKYLLSQDVVSSFSDSWNTVWDLCIKSLSVCEDKSAAMQLLRNILKEIRPANIMSLLNLYMNNSMPPMECSLLLLADCLALCSLPVQLNTYNFASQAVILDEEIAATSCPRQAIIAWLMNASNQCANGMESLIATLMCSLVDTKKGEVCNKTAVSEIRMPHFKFIMKHRLAERLADALDMGFKDLPTLTISSNAHNVQSKYKQFISKLNLYLNIANIIDKYSMWENEGFGLQPVVQKIFDLGMLKLNNFIHECFTSELVNHPQQIAAVIKSTRVFMSNKLTVKMQRLLSSKFNQPTLEHLKKVFRSNLARYVERSVNNPHEAAVLFSDEELPSRLRVLQMSNAVELELITKKDRDCEKASTESLHALIDYGMICNHPLEFFNEILKDLHMEPFLSANQFLFDACADVIFKVSTMLPATGLEEIVVSIVGLLQKCCRGFFQLPYCAEKLWTLFKDITRVVAPVDLPDRTHFMILVGTLYNFLKAESKVTSSVYLKAFECFSELAKHDPSLTWTEFIPRGSAPCWVLEELHLFLKNQSHLIRMCVADTICNTYQHADPFDYSGGISSSQESGPEVTVTNAYQDRRKSFLKTLYTALLNTFDIECGLSPDEIREESVNRTSLALSCLTRLIFAFPYLQKQSIMNVFVIVKVKCIDVVLAQRALQYSSSSSTKTMCCYLSYILSTSLKLKHTVEDLPYQFFGSDNLVSFLTKFRYEICVEYFEQDKMEDLRKFAARFNTSVQSLTQECYGMLMARLTPGLAIHQYGLQSRGGLDVATFNETHKRLISELGGKDATETLMMTCLGDVVLNLISLTFDPVIVNEWGCLEVKLTEPVPPHYPETTIETCLKFLQAASPHSNVSVIGYLAKSSARSIYKILLALTVRIHEAHNDLEKYWRLHQLSFFINLLLNEPQDVFSSMKEYVCNFVFNTYLRLLKTQDGNEMDCIRFQQVLILLITKLVERITEECTDEMIAYFNPVVRGIVSAVVKNPVLMDSAKRLLDFLMKTHSLTFVSCIASLEPFPSSDVAEFQEYDAIQQDKKYGNFRHDWPLQKELEMCLKEIESSAASCTKERLRFLKDLLAKGKRDLERMVRNLETKRFSEECDKDPLHHIIQMLIGVTLTSHDEEVILEASRCLGEIGPVDLSVLVLPTHTNQVKINTSNDALIGIIKIIFSYITSDDIRLVTAAGEVLRNLFEYEECADLAKSKLYDAKLFKILLPFRCFQVQRLKQSMERIDTNMLETKLGLNEMNEYIDFRSWITGLSAGIIACFKGKSSLVAHLLPLCELRVDFCEDVLPYIVYLCLLGGNPIVKRVVTGYFRNFFSKFTTHYNNAADVTRSFTPSSSGTVGTCIFMNKLALRSLLRVIQFLRRHPMPQAMKGSVKLTPWDSNFWLDLNYLDVAKVAQFCGAYLTSILYVEIAATEMDIRHGTQQHYDDGSDEESQEQLYSQGLSMYSRNRSEVSKIEKLLLKAYTSIGEADATYGCGSARFTDVESSMHHMEQSMDWHRLLVLANGSSFDPESCQEAHVALSLKQQGLFNVLWAFLKGTESGETESGSEDDITQVQYECGWRLTKWNMNADKPVYVKDAVEPTSHTAFQVCIYEGIQAGLGGDTQNQLKSIKNGFRSVQTDLRHATLESSENICPFLSRLQMLRVVEDFFEKDLSNEQSLNEFVNKWKQQDRIPASDFKYQEPILFLRNVLLREYNSGKPIRNLDPEISESLLELISKARDAGRLDFADNLATAMASICKTSVQREFEVAKTNWARGKGDVARHILSRLIRKCNHEDDIFPSLLLLYGDWVSISHSERPSVILEKYLQRSCNLYEKKANAPLQEVSKANFVLAKYADAQYQNVSKYIGSEVFTAKQNHLQQARMEEEKMKHLMDLDSRRSAQIIRKQSSYDDEEINYIYKQRTEFLMLALRHYLRGLKASHEQDLLIFRAISLWLENGNDTDEKLVQQTTQIFGEETMPTYKYIVVLHQLSARLSNKSSKMNDLLKGILVKCAEEHPYHTLPVILTQASLHKDENLPKKTSNMKVQLTGRVKAAHDIVESLKANKRLKTLLVKMETVWVALIELANTVEAKRNSEGVKKNIPESIFKKFVHLEDVAVPTSTIPVLPSGNYTGSVVGIHQFGNAYGLVGGINSPKKIDCRGTNGLVYNMLLKGQDDLRQDAVMQQVFGVINKLLQAEPKTRARQLHIRTYKVIPLSQRTGLIEWVENTQTLGDYLVGPTTEPESGAHPRYRPNDYKPIQCRHLLLEARNCGDIEKKFSTYIQICEHFKPVFRHFFFENFKEAGVFFEKRLAYTRSVATNSIVGYILGLGDRHVLNILIDKTTAEFIHIDLGVAFEQGRILPTPETIPFRLTRDVIDGMGVCGIEGVFKKSCEMTMEVLRNNAEIILTVLQVLLYDPLYMWALTNDRVAKVQPSDTSKGGRKSRTSVEPVEDSVKERNNSAARVLLRLRQKLMGIEEEGGATGAISSGSSLSIDGHVSLLIQRAMDPEKLSRLFPGWQPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NG94</accession>
    <name>A0A1D2NG94_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Katanin p80 WD40 repeat-containing subunit B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">Ocin01_02722</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000058">
        <property type="protein sequence ID" value="ODN03976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NG94"/>
    <dbReference type="STRING" id="48709.A0A1D2NG94"/>
    <dbReference type="OMA" id="TYADIPN"/>
    <dbReference type="OrthoDB" id="10251605at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008352">
        <property type="term" value="C:katanin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028021">
        <property type="entry name" value="Katanin_C-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19845">
        <property type="entry name" value="KATANIN P80 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19845:SF0">
        <property type="entry name" value="KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13925">
        <property type="entry name" value="Katanin_con80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008905527" evidence="8">
        <location>
            <begin position="25"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="28"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="70"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Katanin p80 subunit C-terminal" evidence="9">
        <location>
            <begin position="508"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="197"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="420"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ODN03976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="671" mass="74814" checksum="E3E9AD1ACB5EF237" modified="2016-11-30" version="1">MMILNVGGFLLLLLQMWDIRKKGCIFGYKGHNSTVNSLKFSPDGQWIASGGEDNYVKIWDIRVGKVLSEFSDHTGSVTDVEFHPHEFLLASSSLDRTVKFWDLETFSLVSSSLADVPPIRCITYHPNGSCLFAASPDILRVHGWEPPETFDAVPTPWSRIQDIAVSQDQLVGVTTQLTNVSIYVVDLRRVHPVGNSKSMRASLSSGHSLRKNFNKERSSEFAESLNAMKASEESDSLPTDPEDEVNVPLNQRDFRQIFAPHRDCGANSSPADYIPDEEPSLATSTESESPRPESYSKTTKFRYVNSRESSRNRHSPENTPRRASVPNFVPGQVAHNHNNRNLSPGVCLTSRSRSPDCMSRQSSLSDDSSGPYSGRSTETHRSTQLDSGYNSHSQPPVHTGMANYTKLYFITVDHYVLSSPSESSLIPSPSKENVQYSSPAKTNPPLQPLPRSPERPLAHRYDFVPIPIDRPSGLAIDDFLPKKSAVAYDGGIHAVDVSEADVFTNLAREHQPILAVMATRQRNLRIIFNVWQTKDVKTAVEAAVNLHDIAVVVDLLGVLVLRPSIWNLDLCVALLPSILQLLQSRYEAHLTAGCNALRLILKNFASVIKTNIESPIQTVGVDISREERYNKSMECYRHLVAIRAFTLKRQTLQGKIGHTFRELHIHLSSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGH8</accession>
    <name>A0A1D2NGH8_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_02621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000056">
        <property type="protein sequence ID" value="ODN04066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGH8"/>
    <dbReference type="STRING" id="48709.A0A1D2NGH8"/>
    <dbReference type="OMA" id="EAYLGEF"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000001">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN04066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="168" mass="19711" checksum="47DDC9C3BC0C0110" modified="2016-11-30" version="1">MAATLRPYLNAVRHTLTAAMCLENFSSQVVERHNKPEVEVRASRELLLNPVIISRNEKEKVLIEASINSVRVSIAIKQADEIEKILCHKFMRFMMMRAENFVVLRRKPVEGYDISFLITNFHTEQMFKHKLVDFVIHFMEEIDKEISEMKLAVNARARICAEEFLKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGX7</accession>
    <name>A0A1D2NGX7_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">Ocin01_02213</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGX7"/>
    <dbReference type="STRING" id="48709.A0A1D2NGX7"/>
    <dbReference type="OrthoDB" id="6359871at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408:SF64">
        <property type="entry name" value="LINKING IMMUNITY AND METABOLISM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="311"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="15"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ODN04510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="454" mass="50501" checksum="9582B28FF5AB82F5" modified="2016-11-30" version="1">MGSLKVEAGVPKVSLPKLNCENVNGGQPKSASSTTILSEPAIPSSSSSSLMTERRDQTAKRSGPKITARARTAATPPSTHKLISNVSENCNIIVPCSGGMDTNQNEPDELDPLVKVEIEMEAPGVEDSIPVDYNTTYNTDLLDTSHYVYPNNSLRNISEMDVSSSSVNHNHIFSVSSNADYAASTSTSIFSSVINQSEKNYKCKTCGSCFDSIRGLNGHMAAHSIRSISTASPSVYRRNKSSFTCKTCGKFFNNTSTLNQHIIQAHSANLPYFKKTNSKIRKHIPCPICGKLVRSDCLPRHSLIHSGETPYSCRYCNRKFRDTTQQLHHEKSQHTMEVFFKDLPHGTTLADIDGIINDILAQMKKISDSSADKRYQCPYCPRKLLEGQKSCSRTHFLHKHFDKVQSLVKSRYGTNFPVDQHSMLMENVTFASDIQHNDEIQNQHFLDPLVTYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NGY2</accession>
    <name>A0A1D2NGY2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_02179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000042">
        <property type="protein sequence ID" value="ODN04472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NGY2"/>
    <dbReference type="OMA" id="MSRPENE"/>
    <dbReference type="OrthoDB" id="2157184at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="654"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="731"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="324"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN04472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="874" mass="97051" checksum="EA2BC299F73FA783" modified="2016-11-30" version="1">MDGSRTENLNINETLKELQQFVNETEARHNQESQDQQRKSITYDAPTTEIKGSGDNEISNKRNTSLSDDGIDSLMRKLDSLESAQNILEQVFNTGDTNDIDIDALIAQLPLADPTLELNVENGEDVSQRSFNSEIASIQKIIDGGDSSCSIKSEVAGGNNLLSTSQLTDVSTSSKKERAVDDVLREYEEFERSLSRASAIDESFRSDVSSLPPLSAYSSKPEDAINSVPVIKPPVLKSTVSPSIVATTSASFTIPTTTSNNNSQTRMAPIPTRDIYCPPGSAPQNKNVSTKTAKKITEPKPTTVPKSSTRVEVSHSTPGVKLPASSSARSTTSAITTTRTSRELNQEAFKPRNRKSMRSPRTMISPRQTPAENFMDLPTNSSRIGAGGDGYQAIRTGMSNFQDKSEYAVAEAMKTIEKLNAMVARQETLLEAYSNDNQKLWTQLKDSKTESQEKETKFQDVINSLQTEVATMKLNHLVSSSSTANSPRQAAVNKAELQRLREDAELKSQQLMELRKEVLLLHSKLTEARSPVKPKQSVVAVTFSQEKEREYQKNINVLNKQVRTLQNILYSKDQTAPPPAQQQNNTSQTILNKSRPLQRTKSDVTKQNASMHQQAMIKCVRNTGVDAKGLFGRRPGSPGGGININTSGVLQASLSCLEQEREEFENIIAEKNKLIFEKERMILQLKDNVETLKSQLPEDEVVDHGFLDELRSRVITQNKVIQTLKEHLSSYKKMETENILLREEKSILEQQILDLKRKLEMTQNLGKPENEVLSILSEKVDELNSRYYHREKQLDTLLNRLTLKTTTGGNNNSSNLSPLRLSLGQFSNNNCSLGGALSRGRTSGMYSADVLNMADFSPTTSFQLFNAVSDLPEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NH13</accession>
    <name>A0A1D2NH13_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase PLK1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">Ocin01_02117</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000041">
        <property type="protein sequence ID" value="ODN04529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NH13"/>
    <dbReference type="STRING" id="48709.A0A1D2NH13"/>
    <dbReference type="OrthoDB" id="408964at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.30">
        <property type="entry name" value="POLO box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036947">
        <property type="entry name" value="POLO_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="49"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ODN04529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="462" mass="52573" checksum="E09D81A7A25AE8C5" modified="2016-11-30" version="1">MLLKGENNSILKSTPKPGLFRLAWTREGIEGENGIYEIVDLSGSCEVKYFRGRYLGKGGYAKCYEVTQDISNKVLACKIVRKNLHLREPYQENREVMIHQSVKHPYVVDFHSYFEDDRFMYIILELCEKQSLLQLSNKRGAVTEPEARYFLRQICEGVMYLHEDENVIHQDLKLGNIFITSGMNLKIGDFGLAMELDRFECKQVGTPNYIAPEVVKRTGHGIKADMWSIGCILYTLLIGKPPFETGSLKQTLTKIKACDFEIPKGSNLSPEATRLILQLIQLDPSKRPTAREILMDDFITQGFIPDSLPALSLTEAPPFPSAEDQARLVLARKCAYTVSRLPKLYTTWFQTSRSVLLAFPNGTFQTINFSTQRKILLRPAMDAVAVSVLDSGQPKRSYKLDYTSITRKCAHVITIDLEYSVNNAEIVKPDRKLVKQLLSMKAEMNSLEKKILFKLLWLGTFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NHR2</accession>
    <name>A0A1D2NHR2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="17">LIM/homeobox protein Awh</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">Ocin01_01939</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000036">
        <property type="protein sequence ID" value="ODN04752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NHR2"/>
    <dbReference type="STRING" id="48709.A0A1D2NHR2"/>
    <dbReference type="OMA" id="DFGRHIN"/>
    <dbReference type="OrthoDB" id="10068367at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09379">
        <property type="entry name" value="LIM2_AWH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000023">
        <property type="entry name" value="LIM homeobox 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000027">
        <property type="entry name" value="LIM/homeobox protein Lhx9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF127">
        <property type="entry name" value="LIM_HOMEOBOX PROTEIN AWH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11 13" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 12" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="15">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="15">
        <location>
            <begin position="80"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="16">
        <location>
            <begin position="172"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="11">
        <location>
            <begin position="174"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="143"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ODN04752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="254" mass="29004" checksum="AF7F0A45FF58C69A" modified="2016-11-30" version="1">MKSQERTSPPPPVNFSRNVLCTGCGALINDRFLLQVNGLSFHSKCLVCVSCRVLLDNETLCYFRNSNVYCKTDYYRLFGTKCSKCSRSINPTDWVRRARTMVFHLACFACDACKRQLSTGEEFALADDKVLCKSHFQELFDLPNDTHHSSNEESCDGTESSSDATSSSRSKSKTKRVRTTFTDEQLQVLQANFQIDSNPDGQDLERIAQITGLSKRVTQVWFQNSRARQKKHLQKQKRKGCKEHTSMHINTYNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJK7</accession>
    <name>A0A1D2NJK7_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CHHC U11-48K-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">Ocin01_01250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000023">
        <property type="protein sequence ID" value="ODN05409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJK7"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022776">
        <property type="entry name" value="TRM13/UPF0224_CHHC_Znf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05253">
        <property type="entry name" value="zf-U11-48K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51800">
        <property type="entry name" value="ZF_CHHC_U11_48K"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHHC U11-48K-type" evidence="5">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="CHHC U11-48K-type" evidence="5">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="238"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="325"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ODN05409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="429" mass="50196" checksum="DC7CD963E0AF35FB" modified="2016-11-30" version="1">MTTEFILAPGEEFVQCPYNLSHTITNAKILIHLDKCRRSYLNGLSESAQKRAMRICRHNATHHIPYPEMKFHEERCKDAFSVVKYLAYHNSEEGNRDYEKEKTLRQEKESIKLEHQCSSGRAETKPNVSNAWDLEEEDWEAEDTGYKAGYDPKEKLKNEVVLYVPAGLTKSERKKFRLEVREKTAESSMTGEKLELPTALRYEHKPDLTALHIADTVKKEETPQEVEKVETISPQDYEDSRRQRRDNESGSSSRNRDRDRDRRSPDGDSDRNYTRSSDRDRDRNYPRSSDRDRERNYPRSSDRDRDRDYRRSSDKDRNGYQSGSSRREDKSYSESSRKDYDRGDYNERSHSPDGDAYYARQSGNDNIRSEAPRSQSPPPSTSRGSHYDSADETEVDMTFASRREKAEYIDDDFLGFDPFTKDDVQTVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJS2</accession>
    <name>A0A1D2NJS2_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_01171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000022">
        <property type="protein sequence ID" value="ODN05477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJS2"/>
    <dbReference type="OrthoDB" id="49113at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN05477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="210" mass="22649" checksum="647BEAAA30EF1832" modified="2016-11-30" version="1" fragment="single">FNAAIKHFRSNSLSSTTSRTSDSANATSSVNANVTTNSQSVSLPDDYSQNTQDFNSQNVLTKIKTIQRVLGSSATTDLCKWSLEATSGDSAHAVKLIRLKALLPESLLMDRTEHVVSVLEMSHWDVARAAAFLLNNTKSTHVTKLKMLAVSNDESNPVVVADNIGSGSSSISSNNNNIPPEPSPRSSNRDVTGSALHNSKENRFIRPTHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NJX9</accession>
    <name>A0A1D2NJX9_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA-splicing endonuclease subunit Sen54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">Ocin01_01158</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000021">
        <property type="protein sequence ID" value="ODN05537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NJX9"/>
    <dbReference type="STRING" id="48709.A0A1D2NJX9"/>
    <dbReference type="OrthoDB" id="408683at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024337">
        <property type="entry name" value="tRNA_splic_suSen54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024336">
        <property type="entry name" value="tRNA_splic_suSen54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12928">
        <property type="entry name" value="tRNA_int_end_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen54 N-terminal" evidence="3">
        <location>
            <begin position="92"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ODN05537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="616" mass="69228" checksum="6C5B3F449649750D" modified="2016-11-30" version="1">MKIVTGESTSKGTVSGLNVDRMESTASGKFSSLPYQKEKSNLVTSSLNYDECSSGSGIDETEFKTLREESEKIFARNQEECCAAFSFQEVLDTLNTKRVTRKSLLSHVELDPANCRLKLLVDRGNVRARYGYDVGKEAYLYPEEALYLLETGKAEIFCEHVSLSIQRARSLLLVSQREESNNSLFNCTVEEFLVYKHLSRMGYCLYRYISDSPITDNSMSDSLVEEDDHVRMEEDNGAVIEVGLKTNCTPDEVDDIIDLDAPAVSETDKTKRKGLKRTYSTTALQDENLSTESDEMMDSDLEYWNQQVCIASMDEDSCLHGTKVEPGGYTVDEADSDVEIVDEVIYRHGGVEIQEIAHTVGCLKENYFEMHDEPVPSTSRGVTSSQVVVDLVSSDDEEQDLKSYGSRIWSKFIPNSKIIFTVPPSSLIPQTMPDNDKIYELDLKDKSDVSDLELEFLVDEVSLNDDRYGSSDSPHNFNLSGSKSWKDWRQSVFREARNVMNDSLLASSEYINGEAATKKLFLWNETQNEPQTTFHDGKIVFEMYGPVGQGFSRLKALDEDPSYYIFITRHDEPIPDFGTIGSSVDGVPILMAIVCDSGENDIVFITADRSPLTSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NKD5</accession>
    <name>A0A1D2NKD5_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">Ocin01_00970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000018">
        <property type="protein sequence ID" value="ODN05711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NKD5"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ODN05711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="53" mass="6591" checksum="842E9FCA2C2CC0C7" modified="2016-11-30" version="1">MMMRMMTRRKIWTVMWVRKAHILMMRTQSMALHVAQLEFEIRAAGWEDLRVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NL15</accession>
    <name>A0A1D2NL15_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SITS-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">Ocin01_00778</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000013">
        <property type="protein sequence ID" value="ODN05937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NL15"/>
    <dbReference type="STRING" id="48709.A0A1D2NL15"/>
    <dbReference type="OMA" id="VWDEFLL"/>
    <dbReference type="OrthoDB" id="10070917at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06592">
        <property type="entry name" value="GH31_NET37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF4">
        <property type="entry name" value="MYOGENESIS-REGULATING GLYCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="5">
        <location>
            <begin position="141"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="6">
        <location>
            <begin position="414"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ODN05937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="56730" checksum="535A51A89CEC486B" modified="2016-11-30" version="1">MSYGGGTTYNQTWPLNTQIIPDSAFVTGDYTSTTTGAKYGGVIENYFLFSNGIAMHIDEDTPLFVGKQLCISAKNEYPYKFRENLELKYDVCVGNNIRHVHQSTFPTFYEKPTRSPDQDMILKPFWSTWNEFNANVNQSIVIQHARRILEEGFSTNSHFEIDDGWEECYGQNTFNSVKFPDPAGMVQELNELGFRVTLWTHIFINYECKELFNEAFSKGYLLKDKKGKSAFTTWWHGDAGVVNYGIDAFKFDAGETDRLPWEFVLTEGSELSYPNDFTRAYVDAVSLFGGLIEVRTGSRSQGLPIFTRMLDKGSRWGYDNGLQSLIPSLLQFGILGYSYALPDMIGGNNYKPSAELWIRWLQANAFMPAVQFSIVPWSYPENPELSEITKTILAIREENWNEILHAVNSTISDGSPINRPMWWVDPEDRETYNIDDQYMLGDNILVAPVLTENSTSRDIYLPRGSWFSNTGIVFDGPVWLRNYSAPIQDLPYFKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLF1</accession>
    <name>A0A1D2NLF1_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">Ocin01_00648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLF1"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ODN06071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="212" mass="23747" checksum="63234DF2F7AA2EBC" modified="2016-11-30" version="1">MDNTVVKNIVLLRPSGADFYHNMAYKELEVEHLDEEKILTFEYKGNRIASFDSVQQPCISVETEHLTGTTTLSLRDNKPVVVIQGRTNFVNFVLLRAVFPYSTVPVTSGYAEGLKIRFQPIILSKRWPALHRYNIIDEQRGLSLGVLLVPSGGTEMTLAFEETATETQKRIIIGVSAFIIADTFRVKQLANIGLLLLMVSILGLVALLLYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLG8</accession>
    <name>A0A1D2NLG8_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Synaptotagmin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">Ocin01_00614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000011">
        <property type="protein sequence ID" value="ODN06091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLG8"/>
    <dbReference type="STRING" id="48709.A0A1D2NLG8"/>
    <dbReference type="OMA" id="SPYVKIN"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031045">
        <property type="term" value="C:dense core granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030672">
        <property type="term" value="C:synaptic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048791">
        <property type="term" value="P:calcium ion-regulated exocytosis of neurotransmitter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048488">
        <property type="term" value="P:synaptic vesicle endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000016">
        <property type="entry name" value="Synaptotagmin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000182">
        <property type="entry name" value="Synaptotagmin 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001565">
        <property type="entry name" value="Synaptotagmin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF227">
        <property type="entry name" value="SYNAPTOTAGMIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00399">
        <property type="entry name" value="SYNAPTOTAGMN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="187"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="319"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ODN06091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="463" mass="52221" checksum="34380454478A0BEF" modified="2016-11-30" version="1">MPEVGEVWVLSFTEVLALYQALIRCYDDDGGPGKAARRRCTIHRLRKGSSKCEPQSNLSLTEPPCLPPEPPGPTLTEKVLEKAKDLGMRGAEMASEKTKVPIWGIILIFIGILILMLVCCCLCIRRQWRKFKSSEKGKGMVKGLAGNRFVGKFVSDKIQPDADTAALPMNMEEPEPEEEEEVKEVQKIGRINYKLEYDFNSTNLSVSIIACEDLVAMDSGGTSDPYTKVFFAGDKKKKFETKVHRKTLNPVFGETFVFKSIPFAEIMAKTLMIQVFDFDRFSKHDQIGEIRIPMCQIDLAVPIEGWKDLDPPVDEDSEALGDICFSLRYVPTSGKLTICILECKNLKKMDFGGLSDPFVKINLFMNGKKFKKKKTSVKKCTLNPYFNESFTFEITPEQLPKCHIVLTALDYDRIGTCDPIGKIAVGPNQEGKSLQHWQEMIGTPRRPIAQWHTLKDPEEFQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLQ4</accession>
    <name>A0A1D2NLQ4_ORCCI</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein msta, isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">Ocin01_00493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLQ4"/>
    <dbReference type="STRING" id="48709.A0A1D2NLQ4"/>
    <dbReference type="OMA" id="THADECS"/>
    <dbReference type="OrthoDB" id="3174329at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="61"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ODN06200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000094527"/>
        </source>
    </evidence>
    <sequence length="560" mass="64188" checksum="935258A335DDA75E" modified="2016-11-30" version="1">MDINGARTLDIKRIKLSPTDDKPKDASLDKNETDAENFKADDDDGNGTGDISLVYKALEDSPFELDGDPAYGLCLIAKRDLKAGELLHDDIPAFFGPSADLVQDYSTPLCLGCCVVMNDGNGENRCPTCNWPICGDDCDNVEHHKANECSLFVKHNVQFPPNVEIQPCYKAIAIIRGLLIKERNPEMWEQLMTLQWKTQLQLTPFPDFEEIKENFGLAEFGRAEDWTRVLGIINVNSYSFQRIEKKEGSPSFGECLFPIYSLMCHSCTPNCTWAIQYSPEFTMKVRPTVDIKKGEMLSVSYNHEFSKFGFYKRQEKIRERAEFECKCWRCRDARDLGTNLAAVKCFKCKEGYMLPEDASDFEMDWKCDKCPYVMSPEFISSFVESLYEQSDMAEDEAEETGESVVKIFEDFIASNSSVKVHSNHWVIAEAAHAIVKLQASNLSKLTLEELNKFIDFCKYLLQIKNVIAPGFSNERGMLHHYLARGYYMKVKLLLNSNTLKATLSQEEMESIYNVQKYALRFWKENPHYESLTENYKREPEYLMQEAEEIKLLLDGSDVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1D2NLU2</accession>
    <name>A0A1D2NLU2_ORCCI</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">Ocin01_00464</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Orchesella cincta</name>
        <name type="common">Springtail</name>
        <name type="synonym">Podura cincta</name>
        <dbReference type="NCBI Taxonomy" id="48709"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Hexapoda</taxon>
            <taxon>Collembola</taxon>
            <taxon>Entomobryomorpha</taxon>
            <taxon>Entomobryoidea</taxon>
            <taxon>Orchesellidae</taxon>
            <taxon>Orchesellinae</taxon>
            <taxon>Orchesella</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Genome Biol. Evol." volume="8" first="2106" last="2117">
            <title>Gene Family Evolution Reflects Adaptation to Soil Environmental Stressors in the Genome of the Collembolan Orchesella cincta.</title>
            <authorList>
                <person name="Faddeeva-Vakhrusheva A."/>
                <person name="Derks M.F."/>
                <person name="Anvar S.Y."/>
                <person name="Agamennone V."/>
                <person name="Suring W."/>
                <person name="Smit S."/>
                <person name="van Straalen N.M."/>
                <person name="Roelofs D."/>
            </authorList>
            <dbReference type="PubMed" id="27289101"/>
            <dbReference type="DOI" id="10.1093/gbe/evw134"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Mixed pool</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LJIJ01000009">
        <property type="protein sequence ID" value="ODN06179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1D2NLU2"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000094527">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <propert
[file cut: first 33554432 bytes kept]
[document cut: first 30735476 of 33525182 characters kept]
